<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LR86</accession>
    <name>A0A3R7LR86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003742">
        <property type="protein sequence ID" value="ROT62280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LR86"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="419" mass="46291" checksum="C070903D5F48F2CF" modified="2019-04-10" version="1">MILLFLMFLLSLLPLFTSLLLFFLFSSLVTAFPHDLSPSPPILPFLSTVLPLPSLSLALNVVFIHFFVTFLPLPPPAHFLSSSSSFSFSLFHPRHSPSASLYSLFSHFLFQRQSFVTLSSLYYCFFVHLLIFSSSSTPLILVPYISTLSSLTTLPSPFSSLSFYVSSLLSLLSPIRSPFLVVFLFPFSSPISPFPSPISLSFFLFLFSLILLFFPFSLPIFPFPISLLLLRFPLSLSLFPSPISHIPFSSLPFPLLSPLSPYPFSSLRFPSPCSLFPSPLFISPFPFYLPFPPCPLAFSLILSPFPGLPFPPCPLAFSLLPSSFPLFPSISPFPLVPSLFPLSSLPFPVSPLPLFLLSLSLSLLPFPVSPLPLFFSPLSLCLSLSRTYSLSLHLISCCRSSLQSEIPESVVASLELAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVY4</accession>
    <name>A0A3R7LVY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine-rich secretory protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003239">
        <property type="protein sequence ID" value="ROT64532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVY4"/>
    <dbReference type="STRING" id="6689.A0A3R7LVY4"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.740">
        <property type="entry name" value="Crisp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042076">
        <property type="entry name" value="Crisp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013871">
        <property type="entry name" value="Cysteine_rich_secretory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08562">
        <property type="entry name" value="Crisp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57546">
        <property type="entry name" value="Crisp domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="40"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="29848" checksum="C903E7131A6D1BEA" modified="2019-04-10" version="1">MPQFDSATLCDSALKAAAERRPKIFGNKLRLKSLEPGKYRIQKKLVQFHNFFRSKVKPEAANMLAMSWSSAAAVDAQRWADACQLLVHDSAEGREVEEYGSCGQNIFVSTHQVPWFFAVKTWWLEKDNFTYGGNNNDLHVIGHYTQMVWHATHEVGCGLAYCAHAYPRPFYNYVCNYCPMGNFMDTLSRPYKRGAPCSACPGHCKAKKLCTNSCPYGDLWINCKELDAAYHDWLCNTKTKEGLERFRFCRATCSCKDAITYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWC4</accession>
    <name>A0A3R7LWC4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase M12B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_017146</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003170">
        <property type="protein sequence ID" value="ROT64905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWC4"/>
    <dbReference type="OrthoDB" id="6493677at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13574">
        <property type="entry name" value="Reprolysin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="10">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="497"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="529"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT64905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="58391" checksum="8AB16EDAFA98192D" modified="2019-04-10" version="1">MEKNTLSSVSDWLFQNKATLPVYDVAYLMTGKDMADVESGMIQEGLAGIAWRGAACVVASGNKRSFNTGMGEDMGAYYVGVMTAAHEIAHNLGSPHDGKDGAEACSWDDGYIMSYIPGKANKLFFSSCSQKLMKEYMASDEAACLQSTQVGEKIPLSSKLPGELVSMDEQCQKQTGKSDAYASKSVSEDSLCVQLVCQWQVKVGYSIWTYTQSTGRPAAEGSACRSGGVCTNGSCQYWCLRVEDLHDSTSFPLSSISPLLSSLPPPLPLLLLSLLSPLPLPPLSFPFSPPSCFFYSLFPLSSFRSSPLLSSTPLISLSFSLPLSHVSLQLFLLISPPPLSPLLSSPSFLSFLSFYVLSPFLLHLISSTYSSHSTFLFRLLPIPFTLLLSSLHSLFRRSPFLLPISLLPSPLPLPPFLRSISLERTSWLIASYNLPPPLPIRLPSSLPSLPSPHSPPFLPSLPSSSPHSPPFSFSPPPSPHSPPFLPLLLSSFASFPPSLPPPSPPSSFPPPPPLSFASFPPSSPPSLHSPPSSFPSLSPHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXD1</accession>
    <name>A0A3R7LXD1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016256</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003040">
        <property type="protein sequence ID" value="ROT65768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXD1"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="143"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="5">
        <location>
            <begin position="444"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="859"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="884" mass="98466" checksum="0222EC5691F739C6" modified="2019-04-10" version="1">MTYFTKGILASSLPLAVREKVWRSCESVSIYALPGEFAKSVKEKSPTAAVHAGVVTQNEHTHKYDIQQDTRPTQQTGLNPQPPIHNTTPGPVQRHNNQHATTHYNTQRPITNRQHTLHRQYTAPRPSSSKPAITRWLPSPEQCFNCTRYGHIAADCTFPSSCPYHHTVARHNWANCKSFPEQSPSRLEEAYLYLTSNSPISQSANSTCLLPPPSAQHHIALPRDPHGRRARAIEVLAEYDVTIVYLPGRQNVVADALSRAPLPSPAELQACKSTPFPPSFAKRHEARTTAPVLANVANQPVDPPSEEEIRRAQREDPVYMDIIGKLERGEPLVPVRRLPVRQFYLADSGLLFRRATPKKIKGRRGLVRDVVVIPESLEPRVLQLVHESREAAHCGVYKAIQMARQRFFFPLLITKVKKHVKSCKVCPYFKGSTNQPAPALRYDVPDFPFEKVSCDTLSGFVTTRSGNKHILVFVDNFTRYCELVPVPNKSAKVVAKAFHDFIQRYTTPTYFSCDNGTEFQNEVMDNLYQSNGITERLNGSILTFMRSLVDTTSDNWDDLLLTIQSAINSTFHSSLGDTPHFLLYGSDKRLPYDLFQTRRKPEYSDSVGALVFRKVHTSDSMRPKLALALTMLVLMLLAMASPLLAEPGLPERLRAVPASKGTVSESLISPQDIDLILKQAASHKLHPLFTLTDRVPFYSTLKSFLTISGHTITTPPPTFMTACTQALPRLFVCNSRPLPLFSDDCSDAIITNHNIINECSFDSIVPTSRPFLLPFDDISVLYFFQPSTATVTCKEALPDVVVTGIYVLPISCEIVTTSLFIPASHSYATDISVRGLNISPMPGTGCARFRSTYHHSDTCQKSRASQPVNPDAPTPGRHLATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZC3</accession>
    <name>A0A3R7LZC3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_014584</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002820">
        <property type="protein sequence ID" value="ROT67349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZC3"/>
    <dbReference type="STRING" id="6689.A0A3R7LZC3"/>
    <dbReference type="OrthoDB" id="10034090at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11467">
        <property type="entry name" value="bHLH_E-protein_Da_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000001">
        <property type="entry name" value="Putative transcription factor 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051098">
        <property type="entry name" value="NeuroDiff_E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11793">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11793:SF13">
        <property type="entry name" value="PROTEIN DAUGHTERLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="496"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="206"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="419"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="567"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="609" mass="63406" checksum="0366AF3A05D3E1D8" modified="2019-04-10" version="1">MMQPIVNGYTGVQSPLDGAHAGVLSPPPQLSPQPVSPSTSSSMACGVTYSNERHAGSTHVTHMANGALMTRTMHMAPTSVHVRGHNSSHGRRHATLGPYPYSLRGGADHSTNGAALLHPLHQAYGSDDFNQDSPRYTSPKPGGLYGESYFMESGGSDVWGATGGGGTGAAAAAAAAAGAVASYPYPAPSMMGPTSHLTQPHYMPSHIPEPMGYDHMASGLPPMSSFRGPGASSTTGGGSVATSSPLYTHSPVPNHTQATATGNSADSIGKAMSSIYPGEQTPSSYSSNPGTPVSATSPPPLTSGAPSGAQQQWPQPHTPTSPHYERSLPMGSRIDERLEDAVNVLQRHAETSGGVPGAGSHLGPPTHGGSLPPYPSALDSHLGGPPNSTFTSLGSHSQDLKALGVPGLGDVKEKVEIKSEDLTSSHLPTTTVAGSMPAGAKGGKRSRSLSQSSLPHPLKPHGPPLLGLPTSALHSGSSTEDEECTDPETKALREKERRQANNARERIRIRDINDALKELGRMCMTHLKTDKPQTKLGILNMAVDVIMSLEQQVRERNLNPKAACLKRREEEKSDGSKLPPPHLPHPSSMAPPFPNLPGDHLSHGGAGPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZX8</accession>
    <name>A0A3R7LZX8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002750">
        <property type="protein sequence ID" value="ROT67842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZX8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="772"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="934"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="955"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1035" mass="112684" checksum="4A117800832C993F" modified="2019-04-10" version="1">MHGGERTTLPWVKIRRGHLGLKRGVHLVSHPCVREMRRKAGHSWWPVCTGCVWGGGGGWSISRPPSPTTQPATQPATNIHSHPTHHIHSHPAQHTTYTATQPSTPHTQPPSTPHTQPPSPAHHIHSHPTHHIHSHPSHHIHSHPASTPHTTATQPAHHIPATQPATPQPPSPHTTYTATTHHIHSHPPTHHYTATQPSTPHTQPPSPAHPQPPPSTPHTQPPSQHTTYTATQPSTPHYTATQPSTTTYTATQPSTPHTTATQPAHHIHSHPAHTSQPSTHHIHSHPEHTTYHSHPAQHTTYTATQPSPAHHIPQPPAQHTTTQPPSPAHHIHSQPAHSTPNTHSHPAPAHHIHSHPAHTPHTQPPTQHTTLHSHPASHSPSPAHHIHSHPSNTPHTQPPSHNQHTQHQPSTPPYTATSPAHHIHSHPAHQHTQPTQPSTPHTQPPSHTPTYTATSPAHHIHSHPAHTPHTQPPSPAHHIPQPPSQHTTYQHPAQHHIHSHPAQHTTYTATQPHTHTQPPSPAHQHTPTQQHHIHSHPAQHTTYTSTPPAAQRSTHTTATTAYTATHHIHSHPATPHTQPPSQHTHIHSHKPSHNTSQHSPAHHIHPSPPSPSTTTYTATQPSTPHTQPPSPAQPHTQPPPQHHIHSHPAKHTTYTATQPSTPHTQPPSPAHHIHSHPASHQYTQPPSPHTTYTAPATQPAHHIHSHPAHPHHIHSHPASTATAQQHTTQATPHTIPTPAQHTHIHSHPAPHTPHTQPPAQPPPPLPQPPSPSHTTLHSHPAQHTTYTATQPSTTYTATQPATPHTQPPSPAHTTYTATQPSTPHTQPPSPTTHNTTATQPAHHIHSHPAQHTSITQPPSSQQPSPYTDTQPYSPHTSHPPVPAHTTYTTTQPTPTITQPTQPSTPTYIHPITPPTSTHALTHPSLHPVPAPPHTQATPVPAPYTYTATQPSTPHTQPPSPSNIPQPPSPATPHTHPPSPASTPHYTAHHIMRQAPPQHPHTHLSNMDDLNRRAEIRKPATDPTVCQLRDQKVIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M162</accession>
    <name>A0A3R7M162_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative helix-loop-helix protein delilah</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M162"/>
    <dbReference type="STRING" id="6689.A0A3R7M162"/>
    <dbReference type="OrthoDB" id="10063280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11431">
        <property type="entry name" value="bHLH_TS_taxi_Dei"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF147">
        <property type="entry name" value="HELIX-LOOP-HELIX PROTEIN DELILAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="91"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="299" mass="32476" checksum="0E54C00B7A2FF214" modified="2019-04-10" version="1">MEKFEKKFVKEERGGELDSGRPDANNNNNHNSDSSSSSPEERPDAAKSPGPSGGKYQLRPRSVHARRLCDSDWSFGESLRHKPRAAPLSRYRRKTANARERYRMRQINTAFESLRGVLPSWVCSRRAASDMTKIATLRLASAYIRSLQDILDGSAPQDTCSWVLSAILDGPSPKQKAAPGDALSSKLSADVKPDHEASELAPTSVESDFVSLLCEAPSSQAFEDNLASFPFLTSMSDPDPVALLLGVPDPSPGCWEAGGGSGVSTGLPLSRDEGAALCPLVPRCPTLRNPINRKREEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1Z4</accession>
    <name>A0A3R7M1Z4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_017002</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003150">
        <property type="protein sequence ID" value="ROT65054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1Z4"/>
    <dbReference type="OrthoDB" id="6368960at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="9">
        <location>
            <begin position="147"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT65054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="42770" checksum="7D8B741B8D658DC8" modified="2019-04-10" version="1">MVKVGTWTPKLSLGLRGSLFQEKYANFYGAQVNVTSQTFIPKWKEKVVKLPDGREVLHYSGMDYQALVAIADALNFSAKVIPTASFEEATAKVEEGISSFVAVGYSIIPGRLERYDFTRAFDTYKTSFAMPNPKPQSSWYSLVYPLSYEVWLSIGAALAGTSLVLSLPSPGRPHPLNPFLTPQMTHYAEGNQWPGLCSIAQDLYKILLGQDLVQRFVRNLSTRLMISCWLAFSLIIGAAYRSNLTTYLTVPKEPPKIETIQELVGSVDRVLIPSYGKDWINFFLNSESEIYRKLGEIMHTGSTIEEDLSKLEHNHASIESHLLLNYIIAKDFTDAAGRRKLYVGKSYLLTTFSAWPIPHDAPYKQQLDKCLLAFTEVRGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7Q3</accession>
    <name>A0A3R7M7Q3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RCC1 and BTB domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002567">
        <property type="protein sequence ID" value="ROT69383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7Q3"/>
    <dbReference type="STRING" id="6689.A0A3R7M7Q3"/>
    <dbReference type="OrthoDB" id="5981550at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18498">
        <property type="entry name" value="BACK_RCBTB1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18298">
        <property type="entry name" value="BTB_POZ_RCBTB1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="70"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="231" mass="26532" checksum="B3B13C45A3F5A0BA" modified="2019-04-10" version="1">MTQNSKVYLWGHCKGQSVVGPLETGFSSLHEVFALWASPSVTYEPLNVTSFTRSSLAQAMALALDDEETADVVFVVDDRRIRAHRAVLKIRCQYFRNMFQEHWKENSLEEVEVKDYSFVVFRAFLQYIYTDTVNVSPEDAIGLLDLANAYCEEALKRHCERIIRHGITTENAAMLYAVAIKYEATELEEFCFRFALNHMTEVAQTEAFMALDELTVKNFIQRAAQHGAFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAM6</accession>
    <name>A0A3R7MAM6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N6-L-threonylcarbamoyladenine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_010147</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002283">
        <property type="protein sequence ID" value="ROT71533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAM6"/>
    <dbReference type="STRING" id="6689.A0A3R7MAM6"/>
    <dbReference type="OrthoDB" id="10254073at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd24132">
        <property type="entry name" value="ASKHA_NBD_OSGEP_like_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000038">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000295">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03722">
        <property type="entry name" value="arch_KAE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="11">
        <location>
            <begin position="29"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="130"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="294"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT71533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="335" mass="36589" checksum="896CA26B42390989" modified="2019-04-10" version="1">MVVIIGLEGSANKCGIGIIRDGEVLSNPRRTYITPPGQGFIPHDTAKHHQAHVLEVLHQALAEASITPEEIDAVAFTKGPGMAAPLISMAVVARTISQLWNKPLVAVNHCIGHIEMGRLVTGAQNPTVLYVSGGNTQIIAYLGQRYRIFGETIDMAVGNCLDRFARILMLSNAPSPGYNIEQMAKKGKKYLPLPYCVKGMDVSFSGILSYLEERADKLLKTGQYSKADLCFSLQETVFAMLVETTERAMAHCGSQEVLICGGVGCNVRLQEMMGKMCEERGAKLFATNESFCIDNGAMIAQAGYCMFQSGITSTLDDTWVTQRFRTDDVPVAWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCF2</accession>
    <name>A0A3R7MCF2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Laminin G, domain-containing 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001425">
        <property type="protein sequence ID" value="ROT78148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCF2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="507" mass="54910" checksum="3EE311AA8838C7F2" modified="2019-04-10" version="1">MHLNPETERDGVHDPRPRLSSLRCGRDGRRVRESGLTAAPRTCHVLFAAFFAAFFAPLFALPPSLPPSFAALFALPPSCNPLCHPLCATTLCPLCHPLATLFATSLPPSLPPLCHLFASTLFATLFATLFATLFATLFATLFATPLCHPLSLCHPLCHPLRHPLCHPLCHPLCHPFLRHPLATLFATLLHPLLPPSCHLFRHPLSPSSPPSFGHPSSPPLFAHPLCHPLRHSLATLLPPSLPPLALFAPLCTLPLLPPSLPPSLPPSFAPSLPPSLPPSITLFATLFATLFAPPLRHPLFHPLRHPLCHPLCHPLRHPLCHLFFLCHPLCHPLLPPSTLLPPLPPSSPPSSPPLLPPSLPLSAMPPSLPPSLPPSCTSLPPLFPPSLPPLSLTSLPPSLPLSLPLYPLCHYPLCHPLCHPLCHPLCHPLCHPLCHPLCHPLCQPSSPPSSPPPPPPSLPPSSSSPPGTSPHVTRSTCTESRVFEHGEDRLFGYGKDRELRFRLLFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MF68</accession>
    <name>A0A3R7MF68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative homeobox protein Nkx-6.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006732</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001850">
        <property type="protein sequence ID" value="ROT74749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MF68"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007417">
        <property type="term" value="P:central nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050877">
        <property type="entry name" value="EMX-VAX-Noto_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339:SF67">
        <property type="entry name" value="GNOT1 HOMEODOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339">
        <property type="entry name" value="HOMEOBOX PROTEIN EMX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="98"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="100"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="176" mass="20110" checksum="F26A5D9F73BEE108" modified="2019-04-10" version="1">MSSYLSHHTANMDQISVMNFQPFAWAFSHPWAPPVSPPPAHSFTPSRMSHKAKAFTIDALLGLDTQKDLPATTASPPASPLSLLQRESSDTGLRDAPGKLKRHRTVFTDSQLQRLEEEFQRQQYLVGPERRYLARQLELSELQLKVWFQNRRIKWRKNQLSATQDRDACVSPPTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJC9</accession>
    <name>A0A3R7MJC9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative E3 ubiquitin-protein ligase TRIM9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000577">
        <property type="protein sequence ID" value="ROT84238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJC9"/>
    <dbReference type="STRING" id="6689.A0A3R7MJC9"/>
    <dbReference type="OrthoDB" id="295536at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003649">
        <property type="entry name" value="Bbox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF15">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00502">
        <property type="entry name" value="BBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="261"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="44924" checksum="D075DB94777B4C48" modified="2019-04-10" version="1">MRGSCLGVGGGPAVWRHVRATKRSCRLAGGLVRGWGESAPEPAAVVNRQGFSVAPTIVSDGGGNTVSRVLQRSVQALLAEPVGGQQAGPPGHDPDPPDGGADSDKASVYSETDSGVVVASRPTSYVSSPETTVNNEGGDGQPAAGQQQGVRCPVCHKVSALGPGAAADLPRYTAMSRIIARQRGDPSLGEASASTSAPTGTPATLPPCQLCEGPPRAATTECQQCQVLYCGPCLTSCHPPRGPLATHTLGSVAPLGGSIPGAGEVCAAHGERPSLYCLVCRWSGCRECGPGHSQHDLQPLDNLAKTHKAELSESLQQLSGRAKSAHSHITNLKTFQDRVNAHCDALAAEVERQCAELMEAVSAARTRLLAQLAAERESATKVYRDQAAGCTRRLHQTTALVQFCIEGAPTPAAFMQRSNPLWTLFRAFCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJZ8</accession>
    <name>A0A3R7MJZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative collagen alpha-1(XXII) chain-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003389">
        <property type="protein sequence ID" value="ROT63722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJZ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051159">
        <property type="entry name" value="Hexapeptide_acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23416">
        <property type="entry name" value="SIALIC ACID SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="717"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="900" mass="103235" checksum="F62D32EC046DF6F1" modified="2019-04-10" version="1">MADGESPSAESLSSSPSESSPSAETSPSAETSPFFTIGRGRIESSPSAESSPSLHHRQKPSAETHHRHFTIGRIFTIGRIFTAEAEENLHHRRQKLHHRSPSQKLHRQNSPSAETSPSFTIGRSRIFTIGRGRTHHRQNLHHRQKLHHRQNLHHRQKLRRKPSQNSPSQKLHHLNRQNLHIGRIFTIGRKFTIGRNFSFTIAEIGRSFTIGRSFTIGRIFTIGIAETNFTIGRSFTTSPEVHHQNLHHSHRQNLHHRQNLHQRIFSRTSHRQKLHHRRIFTIGRSFTISSHRQNLHHRQKLHIGRNFTIGRNFTIASPSAESQKLHHRSTIGRIFTIGRNHRQKLHQNFTIAEASPSAESSPSQKLHIGRNHHRQKLHHFTIGRIFTSAEASPSESSPNFTIGRNFTIGRIFTIGRNFTIGRIFRQNLHHRQKLHIGRNFTIGRNFTIASPSQKPFTIGRSFTIGRIFTIAESSHFKESHHRQNFTIAETIAETSSSPQNLHHRRSFTIGRIFTIGRIFTSAELHHQNFTIGRNFTIAETSPSAESSPSQNSPSAESSPSAEGRIFTIGIFTAESSPSQKLHHRQKLHHRQKLHHRQNLHHRRIFTSHSPSASPSIHHFTIGRQKLHHRRSPSAETSPSAETSPSAETSPSQKLHHRRKLHHRRKLHHRNSPSAETSPSAELHHRIHHSAETSPSALHHRRTSPSAEFTIGRSFTISSSAETSPSAEASPSAEASPSAAETSPSAETSHRQKLHHRRIHHRQKLHHRQKLSSQKLHHRQKLHHRQKLHHRQKLRQKLHHRQKLHLGRAEASPSENFILAELHIAETGRNFTIGRNFILGRNFTIAETSAALTWWQQEVLERPTSREKRRQHDQPLVLPRNVFHDKDAAVGQTTHNLKRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML50</accession>
    <name>A0A3R7ML50_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001207">
        <property type="protein sequence ID" value="ROT79672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML50"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="44897" checksum="5BA760D4D7186129" modified="2019-04-10" version="1">MATGSGTRATCWSCPSLTTIRRLSLASILCEFGDLQAIQINPFLLQDNIRNPEVQCSGYPRLDLEAWREAEARSLHPQPLPMPFSQPEYRYPFLVLPSSSSSSSPYSFLTPPLSSSSDLPFSSSYLRFPSSDLRFPSADLPFPSSDLPFPSSDLLSPRPPLSLSAFLRPFFPPVPPSSEILGVSPSSSDASPRLILDFGSLGDASSVLDPSPQLHLNPCLALHLNPCLFILAWRFTSILAWRPQSLPGASPLSLGPEPLIVPEMPVPEIPVPEVPAMSKGDSSAALKSESQSVLESLPGREARQSTKSCLNGSSPQLIPESFLPLMPQHLPQSVSVPDYILRSMAKSSPQPMSEPSLSPLPESLSLCPQCLDPWPQPYVWILGSAHPWLSLCLSLAQPMSVLSLCLDLGSAYVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MP73</accession>
    <name>A0A3R7MP73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002916">
        <property type="protein sequence ID" value="ROT66627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MP73"/>
    <dbReference type="OrthoDB" id="6380771at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="44215" checksum="59A5F46EF49875CD" modified="2019-04-10" version="1">MTKKSEVRPNINHLSPPPAHLDVACSKPGVSWADESNRSPGRSHPLRSSSQSGRGKGRGAKGGRHASPVSDRNRRQVGRKRDNLPSKQRSRSPSGRQKAPGSSWDKREAKSSESFGKEGVASARNQSPERHGRNGSPWLEPVTPEKQSHGTREHSLTPGENASEDQERKDQSAKAKAAEEDKEKHPVDQKNHQTEPSNKKHESLTRVEDNDTEEEEEKDTSKTRNVKEGKKEDIDSSDLRHMLKRKIESTESGRGNSSSGKQDMDEKDEKRARRDKHEDRPRVLVRTKSRQSESTRKKHDGKPLLVTVASGENRHVMSGDVVNKRDEGKGSQRLSVHLRLGPAKTSWEEGKSGSVQGTWMQFLVWRDAMRLLPHVLGGSLTHFFCTWNLSLTQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MVJ7</accession>
    <name>A0A3R7MVJ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartate aminotransferase</fullName>
            <ecNumber evidence="10">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_010897</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01002382">
        <property type="protein sequence ID" value="ROT70795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MVJ7"/>
    <dbReference type="STRING" id="6689.A0A3R7MVJ7"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006533">
        <property type="term" value="P:L-aspartate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000026">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000160">
        <property type="entry name" value="Similar to aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="11">
        <location>
            <begin position="55"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT70795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="47025" checksum="C92C08C477580699" modified="2019-04-10" version="1">MAVAGPRTLNLVRQNQASIQHVCSRASSWWSGVEMGPPDAILGVTEAFKRDTNPKKMNLGVGAYRDDNGKPFVLPSVRKAEELIVSQKLDKEYLPISGSAEFCKHAITLALGSDSPVVADGLNVTVQGISGTGALRIGSTFLSKFFPGPKNVWLPAPTWGNHVPIFKHVNMDVNQYRYYDPKTCGFDFNGAIEDISKIPKGSLIMLHACAHNPTGVDPKAEQWDEMSKVIKERELLPFFDMAYQGFASGDVAKDAYAVRKFLADGHKICLSQSFSKNMGLYGERAGAFSIVCSDKDEAARVMSQVKILIRPLYSNPPLHGARIVSTILSNPELNSIWLKDVKGMADRIINMRTKLKENLAKEGSIRDWSHITDQIGMFCFTGMTPDQVEKLTKEFSVYLTKDGRISVAGIASSNVEYLAHAMHHATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N1Q4</accession>
    <name>A0A3R7N1Q4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative organic cation transporter protein-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006629</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001840">
        <property type="protein sequence ID" value="ROT74872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N1Q4"/>
    <dbReference type="OrthoDB" id="6348391at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT74872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="21381" checksum="1A3F2826314CD093" modified="2019-04-10" version="1">MFGVTIGAPFNGVLADRYGRKMTVAVGFVAYSALAIGSCWIPNLSALLLSRFLMGAVHPTIQKTGYILGMEVADPKWRTHIGIVLFLPWALGLMAWGGFAYLVREWRMLQLTVSLLCLAFLPTLWFMDESPRWLAVRGSTGAPSECCRGPPGGTGSPCPRGRASAPAQGRSQGRGNGTPAPRRPRPHRERLVQKAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N1X7</accession>
    <name>A0A3R7N1X7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001815">
        <property type="protein sequence ID" value="ROT75053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N1X7"/>
    <dbReference type="OrthoDB" id="6366139at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22139" checksum="76FB325E9498D76C" modified="2019-04-10" version="1">MRMPQEKGQESEDGKTEAKQELSGIVPDVAEFAPVENPGPLSLEHLGPDKELFIVRMPYGMVQPPKLANVNLTLDSKKKRSVQIDNHLLSVSAYESSTVGSTPSIFLPDDDGELHQVKLNIAGQIILKHEPQSSSDNPTIDINTLRAVKHQPPSDIQERNFLSRSITEKRILTTFKATGRKERKADIIEKKNCLYCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N5E6</accession>
    <name>A0A3R7N5E6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative agmatinase, mitochondrial-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_003573</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001484">
        <property type="protein sequence ID" value="ROT77747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N5E6"/>
    <dbReference type="STRING" id="6689.A0A3R7N5E6"/>
    <dbReference type="OrthoDB" id="9992747at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047971">
        <property type="term" value="F:guanidinobutyrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033389">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via agmatine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11592">
        <property type="entry name" value="Agmatinase_PAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.10:FF:000002">
        <property type="entry name" value="Agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="ARGINASE/AGMATINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358:SF26">
        <property type="entry name" value="GUANIDINO ACID HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="40428" checksum="4611D1714DF1F833" modified="2019-04-10" version="1">MSTKSAKRRLTRGLFGVVLRYFAHPAMLSKAASSVPARVAATGALRTSSHAADGGAKAFNQPLSPNYLTRAGGIASFMRLPVQDDTQGLDACLVGVPLDVGTSNRSGTRMGPRQIRTESVLLRPNNQATGAMPFESLNVADVGDVPMNIYNLPEACKHIRSHYSELVKDGCIPLTMGGDHTITYPILQAIKDRYGTVCLIHVDAHNDVSDTMLGAKITHGTPFRRAVEEDLIDPKATVQIGLRGSSYTVDAHAWQISKGFRIVQAHQCWHKSLEPLMEEVKAMMGDRPVYLSFDIDAIDPGFCPGTGTPEIGGLTPIQALEIIRGCRGLNLVGCDLVEVSPPYDFEGTTALTGANLLFEMLCVLPRVKYYDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NS11</accession>
    <name>A0A3R7NS11_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="5">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016839</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01003119">
        <property type="protein sequence ID" value="ROT65218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NS11"/>
    <dbReference type="STRING" id="6689.A0A3R7NS11"/>
    <dbReference type="OrthoDB" id="3200163at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="7">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="7">
        <location>
            <begin position="161"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="234" mass="25477" checksum="8AF3182AD7C61D50" modified="2019-04-10" version="1">MVYIHGEAFTWGSGNLYDGGVLASYGQVTVVTMNYRLGPLVQFKIDHRPTCSRCFTPFISVQSSIHFSILRTFVVYLTHNSPPSPSPPPPYPLALPPLSSLPSTTFPTLSLHHLPHHILPPPSTFSPSTSFTIPLPSPPLSLHYPLSPPPRFLNTSPSGSGRRGVAGNQGLLDQLAAISWVSENIVHFGGDPERVTLFGHSAGAACINYLVVSPVVVPGLWALWWRVWLVRSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NTE1</accession>
    <name>A0A3R7NTE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Insulin-like peptide 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002974">
        <property type="protein sequence ID" value="ROT66221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NTE1"/>
    <dbReference type="OrthoDB" id="10044229at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018533445" evidence="2">
        <location>
            <begin position="19"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="179" mass="20228" checksum="6F9972073C8714C2" modified="2019-04-10" version="1">MVMSMMLAVFLLCSTSLALDPDFVRQIESRTELEWQALWSEERLALCRAKLRQNLDAICGKDVFRRSSVERRRRRDKRDEGRDGSKPLPAESDEVPRANPSTPDTGQAPDKRRSPFLSVQQANLFVTTWVHDQGGRRRAGPLQAPSPVALHHHRVLHGRRLHLGRVCGVLPVVQPSAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P0F5</accession>
    <name>A0A3R7P0F5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6356350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF444">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="360"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="470" mass="51131" checksum="7470ABD98EEBABF3" modified="2019-04-10" version="1">MXHRVGSHELLAFLDSGSAVSIIPVSSLSKCNTPSACTPTPYIVHGASGSCLDVVGEVSLTIHLSDVPIPHPFVVINGPAVPGDILLGYDFMAKTGLHQIPRENVAVHFGRVYALTPPEEYGVDRTPLNHRKSSDPLSSRQRQGHHRSPDTSATTATLSGYTQPKVTPTWLQELHPTSGDLSTHMDPSVRFPLLQTSETTVLPPFTDCVVPVTIPDTSGTVLGARLRGHAPPIRMMDTAAPTFHTSTSPVTVPRSPDASAPSTAHVPDVTAVDFAEGPAILGGLFKEFPLILPSTERPIGRTNILEHSIHLQQDAKPVYIPAYRVPHSRRQAFEDQINKLLEDDHIEPSTSPWSAPMILVPKKDGSLRPVIDYRKLNALTIPDRFPIPSLRSLLQDVGKGHAVFSTLDLQSGFFQANGQGLASTYGILHTTGPLPVQVDAFRSQKFTNTFLPSYVHYHGRLDREHRVPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P4D7</accession>
    <name>A0A3R7P4D7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Fructose-1,6-bisphosphatase isozyme 2</fullName>
            <ecNumber evidence="8">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">D-fructose-1,6-bisphosphate 1-phosphohydrolase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23">Muscle FBPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">C7M84_021395</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="28 29" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="20">Homotetramer. Interacts with ALDOA; the interaction blocks inhibition by physiological concentrations of AMP and reduces inhibition by Ca(2+). Interacts with alpha-actinin and F-actin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Myofibril</location>
            <location evidence="4">Sarcomere</location>
            <location evidence="4">Z line</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 24">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01004485">
        <property type="protein sequence ID" value="ROT60920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P4D7"/>
    <dbReference type="SMR" id="A0A3R7P4D7"/>
    <dbReference type="STRING" id="6689.A0A3R7P4D7"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000005">
        <property type="entry name" value="Fructose-1,6-bisphosphatase isozyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006779">
        <property type="entry name" value="PRK09293.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF1">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0106">Calcium</keyword>
    <keyword evidence="17 24" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="15" id="KW-0965">Cell junction</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 24" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="26">
        <location>
            <begin position="65"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="27">
        <location>
            <begin position="257"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="25">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00037516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00038670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00040321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00042757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00043165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="ROT60920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="42054" checksum="33887C7D1DB39968" modified="2019-04-10" version="1">MPSGVKSGTTVSSSSRQITKAERCPERQQTLAFRLRNSRRDDLSETSPAPFKMTSTGQAIDTDSMTLTRFTLGEQKRVPHATGDLTQLLVSIQTAVKAISSAVRKAGIAKLYGMAGDVNVQGEEVKKLDVLANDLFINMLSSSYTTCLLVSEENKTVIEVEQERQGKYVVCFDPLDGSSNIDCLVSIGSIFSIYRKSTEGVPTVSDALQPGNQIVAAGYALYGSATMMVISTGNGVNGFMLDPSIGEFVLTDPNMRVKEKGKIYSLNEGYANLWDPAVSEYVHGKKAKKAGARYIGSMVADVHRTLKYGGIFMYPATSDAPKGKLRLLYECNPMAFLMEQAGGQATTGKMRILDIVPSDIHQRTPIFLGSTDDVQEIIDLYKKHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P8T9</accession>
    <name>A0A3R7P8T9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001344">
        <property type="protein sequence ID" value="ROT78721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P8T9"/>
    <dbReference type="OrthoDB" id="6359757at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="283" mass="31602" checksum="C7C7D88D533C5EE6" modified="2019-04-10" version="1">MIKQKPPSFSSVGASMSSGSGGSTKYMLGGSSAPIHHPTRYSVMGMGRVLDPSRLSHALRTPTPEASRYEPNFMLGPATAHDYPATTTSPSLLRRPPAATPSSRRMRPPSPKPHWRSESRYMSRPKLNSDKKHEARYMLHPPTPELPRTFENKYGSSGMEKGVGEKDLGTGSGLYDTYWHIPRATLWCSHKGCVYDSQPCKECQWKQDDCSSTCSSVNPPPTFTALDKYQPVRPRPKCHQCSCGIIFAITTVFSLLVLLLITGFILYIEMVLKYQRDNVKDRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9E2</accession>
    <name>A0A3R7P9E2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001280">
        <property type="protein sequence ID" value="ROT79179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9E2"/>
    <dbReference type="OrthoDB" id="6020705at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052212">
        <property type="entry name" value="PH-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12156:SF5">
        <property type="entry name" value="FI18040P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12156">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="47588" checksum="0CF6EC9F79DC4647" modified="2019-04-10" version="1">MFGKLQQPRAFGSTIPTPPGSSHLARTPSLTSVSSSPSLSPLTKTPSQTSLRSSKTDISKLQGSKSDLTKSESLSNVSRVTPKLDLSKVSSKIDCGDKSLLKRPPSVSSIDSMDGGTVSPRGPPYKAISTTPFRKPITPTPLKSSTRKSDPQAKLPIGSAGKSAASRDERTPSKESSPRSDMKKTSSFVEVAEQRERIAAREVKIGELENHMMDMTATVRLETEILERERQNLLSKIAKERGRLTVADRRLGELIRLGLTPTNGQCSPACSSDTEESGAPELVERLARLQFLDRSQEDLDRIHQVTSATPLGCNDGTLGRKTSATLMEIERNRQILLAKQGTMVIENERRRVEELKRRVADEVKAQWEEKKAKEQRDINCASLNSVGSEDSSLTSSDLHTESLSSDDVLEKRSSGESVGRDMPQVKVGHSNHLSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEV4</accession>
    <name>A0A3R7PEV4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022531</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cadherins are calcium-dependent cell adhesion proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000568">
        <property type="protein sequence ID" value="ROT84264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEV4"/>
    <dbReference type="STRING" id="6689.A0A3R7PEV4"/>
    <dbReference type="OrthoDB" id="6381129at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000031">
        <property type="entry name" value="neurogenic locus notch homolog protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.900.10">
        <property type="entry name" value="TCF3-CBD (Catenin binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000233">
        <property type="entry name" value="Cadherin_Y-type_LIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027397">
        <property type="entry name" value="Catenin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01049">
        <property type="entry name" value="CADH_Y-type_LIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="238"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="293" mass="31361" checksum="DF3750570DFAA6F7" modified="2019-04-10" version="1">MSAWAPCLHDGTCYDLHPGYQCVCGPGYTGENCQWAHDAYSGLPLSAPAALAALTLSFLLVVVVGVVVSLRLHRHWRRRERRDEPPGDTSPQEVVKGVKESPTTRLAQDVEQESFLERLKIKESQAQPALRKAGRCLWDKERISEKAEKGDSPCTTMAGKVTAKGVLCEGKSRTSGTVPEPLLPQDDLRAYAYEGDGSSAGSLGSAVSGLRSEVSDEGGIRPLVSDFLEVMDLLRNLPDKEKTPTSDSKTPAEGEGVKGSPPAPTLSKSPSKPSPRPPNPTVLPGNSEMTTAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF40</accession>
    <name>A0A3R7PF40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000508">
        <property type="protein sequence ID" value="ROT84706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF40"/>
    <dbReference type="STRING" id="6689.A0A3R7PF40"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="43100" checksum="D3E0C5AFE7F7E870" modified="2019-04-10" version="1">MQSLTLSTSFSWRHKPTGFTRHISLTAHALAAQFVTCYCGDDQVSVIHNRVSYRPYVIAVFLTTPLFLHPHLAPTPYSPPYFTPFHCQLTTSLLSPPPPRSTPLPSLHSLPLPANYSSLFSTLLSSPPHLAPPLTPLFPSLPLPANHSSLSPPPLAPTPTPPLFHSLPLPANRSSLLHPPPTRSYPLLPPQFTPLTYQLTTSPFSPPPTSLLPLLPLTSPLPLQLTTPLFLHPPPRSIPYPPLISLLPLPANHSSLSPPPHLAPTLTPPPLLHSLPLPANHSSLSHPPPPRSYPLLPPHFPPFHCQLTTPLFSTPPPNHSSLSSPPPPRSYPLLPPYFPFHYQLTTPLFLLPHLAPTPYSPSLHPFHCQLTTPLFSTPHLAPTPYSPSFPPSTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHJ8</accession>
    <name>A0A3R7PHJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT72020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6358812at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="721"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="883"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1144"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="405"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="549"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="757"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="818"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="883"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="911"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1085"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1144"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1325" mass="146254" checksum="EB7848FDDA8DD2EC" modified="2019-04-10" version="1">MIHIARQSMAKMRNVFWLPLSHYHHHTCSPLPQPLLTITPVFLAAARRQQQGGPVAHRSLIQQRTSRPDSRRAAQDVLQWDTPLEDSAYKTRLEDGKEQVLSNDSTKAGQTEERGCSPITVLEARPEVDHVATRPRSRAGSHTITTTTSWGAPVTTTTSIEVDDDQSARCVQLTLHSESRVTLHAPGGVWEGLHGVEQQPEHQDEEQQPHEDKHVGDNDVPAEASPDAGPENKSEGETLTEQDFYDDIHQAKDAHELESKETECAIPALSGDDSAYLASEATAPSAHRPTTLMITSNSNESTDDAECTANDLTKLGREDDIPKELKEETSVTEMEDLEEQGMGELAVSERPPGSESGAVPRPERPARPAPRTTTLVKVKVEKRPITSHLLVRERSVHEHQPTVHVPSVEEEVRGLMQEVKEATSQIKQEVKELRQADTPTPDTPTPLREFKEFLNREEEQELERLPTIKEMCRESEEDASGTVGGEHLRGHEHLRLDLDVPTLGRPIPVQAVQRSGDDSSHPDSGYSTLEGYYAVGVDPYHTSKYKSCSEPVPEGSPSEPSIKSELESPSSLVDSSDLSPVDSASATEEKGRRFHAENLSSGNITSLAVNMPVGTQMETTTLGVPGGQSPIGEMNGQDIQDALTDVEDLNMDGESPIPKQKQLLLLPEKETGAVTDTEDMDLSGDENDIIPEKANLPTIQDLGVLPEPTKEVINLTEGYAREASPLLLSDSDSEREDVQNRHKKNIKKGEKMSELEVPGDDEPEGVTDVEDMVASGDEIEEQVQVEDSLPDHYLDQGEGVSNQEKMKAASPKPKVFKHHEDSSDDEKRSKKQVRRRSKASLTVQPKEDGVAMYDTGAITDSEDVAASDTEDIADIVAAPLKKKESSIIPEPHAEKIRISETEEAPAKDSEGETDEEGFQLDDNEDEKPLVPRKRVVSEPIEKVVKEALEVEEPCEAALTDTEDFDLEDKEEEEVISDIASRIPTEGEIYTIKELESEYGQVTKKEIVKDADAELKELIREAEAGGLTLQEALNCEALTDVEDLDDDEPGKPKPKIAPSKKVQKDETATDEESVDESDIEEEIRKPPKRTRHRGKRLPLVPQVSEVRFVETDQGPLSIIITPDNLDNNPDQVVKDKVTGVVFLESEEKEEATTDVEELQSSDDEGQKRRASILNAPQLTTEPATDTEDFDVDAVEVDRPLSPLPPDLNYNVLSSPKREIIHIKEDKYGVPQVTIRKLQKDELLVSDVEDMAMTDTEDIEVSDAEALRLVGATTDSTAEFELPDTGKIEVSSTMKQKNQALHVDADEEGGSTDVEELQMTKKIQTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PI13</accession>
    <name>A0A3R7PI13_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RPB5 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_014735</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively. In RNA Pol II, this subunit is present in 2-fold molar excess over the other subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002834">
        <property type="protein sequence ID" value="ROT67209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PI13"/>
    <dbReference type="STRING" id="6689.A0A3R7PI13"/>
    <dbReference type="OrthoDB" id="248779at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1340.10:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020608">
        <property type="entry name" value="RNA_pol_subH/Rpb5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007129">
        <property type="entry name" value="PRK09570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01110">
        <property type="entry name" value="RNA_POL_H_23KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="10">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00064429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT67209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="193" mass="22308" checksum="274D342D6D6EE8FA" modified="2019-04-10" version="1">MQLCHDRGYLVTQDELDQTLDQFKEQFGDKPSERHPARSDLIVLVAHNDDPTDQMFVFFPDEPKVGVRTIKTYCTRMQEENIQRAIIVVQSGMSPSAKQALVDMAPKYILEQFLESELLINITEHELVPEHVVMTAEEKTELLQRYKLKDNQLMRIQAGDPVARYFGLKRGQVVKIIRPSETAGRYISYRLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIG0</accession>
    <name>A0A3R7PIG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008637</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002086">
        <property type="protein sequence ID" value="ROT72970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIG0"/>
    <dbReference type="STRING" id="6689.A0A3R7PIG0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="41397" checksum="2CEFC94FB3306F05" modified="2019-04-10" version="1">MLACLPPPLYVSVYAACLPSPLSMLACVPYPLSISVCLVSVSPYVSVSPLPLSLSRQRVSPPPLSVSLSPLPLSLSLSSLPSLSLCQPVSPPPLSLSACLPSPLSLCQPVSPPPLSLSACLPLPLSLCQPVSPPLSLSACLPPPLCQPVLPPLSLCQPVSPPSLYVSLSPPPSLCQPVSLPLSLCQPVSPPPLSMSACLPSLPAVSPPPLSLSACLPSPSLCQPVSPPLSMSACLPPLSLSACLPSPLSMSASPLPLSLCQPVSLPSLCQPVSPPLSLCQPVSPLSVSLSPSPSLYVSCLPSPSLCQPVSPPPLSLSACLPSPSLYVSLSPSPSLYVSLSPLPLSLCQPVSRPLPRQPVSPSLYVSPLPLSPFLHVSPRTVDGWAKLFDIWDLNLEEVGDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJS0</accession>
    <name>A0A3R7PJS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative vacuolar protein sorting-associated protein 13C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_012993</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002627">
        <property type="protein sequence ID" value="ROT68842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PJS0"/>
    <dbReference type="OrthoDB" id="6373482at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056747">
        <property type="entry name" value="VPS13-like_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25033">
        <property type="entry name" value="VPS13_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Chorein N-terminal" evidence="6">
        <location>
            <begin position="274"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="VPS13-like middle region" evidence="7">
        <location>
            <begin position="1020"/>
            <end position="1897"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding" evidence="8">
        <location>
            <begin position="1998"/>
            <end position="2511"/>
        </location>
    </feature>
    <feature type="domain" description="Intermembrane lipid transfer protein VPS13-like C-terminal" evidence="9">
        <location>
            <begin position="3096"/>
            <end position="3217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1520"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1831"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1524"/>
            <end position="1533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT68842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3239" mass="361009" checksum="3B8C0089A2949916" modified="2019-04-10" version="1">MVTMQNLHLFTFYLFPFLFRLLLSIFISLFPYSLLPSFPCLLFVPSLLPVYSLHPCPFPFPPPPFFLSHLFLPLPSPTLIQSLFLSSHFSLSPFLPLLILGLYSTSYPYIHPPSPFHPNPSYPVYSSPFPLIKFLTIPLPSLLILPPPSFRSYPSSYFLSTTFLLAPSIITPPPTFSSFTPLPLSLPFLPSPYTLSPPPPYPFPSYPLPAPGRQLPSKAVTTEASPRTSTTHLLSHTLNYHRLYFVYYRLVPSAIVYHRLSITYRCLPSFAFNNHRQWFVTAVWHYAYNCNLENIQRIHRNWSWKHIREHRARCRSYKAVYKLKLENKKLTPEQVKEIEDGERALDVFNITLMRRQAEMEVEREGALRKQEQQQQKGWFGGWFSWGGQKQDEKDAAEGSLVKKLEEAMGDEEKKNLYEAIGYSETGIPPEYPEEFEDIQLEFLLKQLVLIITDDENEGANVTKAKLNTVTLDLKRRSAADSVRVVTSVQSFVVEGFSTDGSPPELVTSEDTSKEKPLLQVLFETNPMDKSCDQRVKLEAQPLQLVYDAATFNQLRDVFAPPKNISLQQLQAAALNQLEVVKERSVTGLQAAIDNHSVLDLNIAIAASHVIVPENGVYSKDCSALVLTLGSMTMKTVPRKRDAPALTDLVTRGMSQEEVVEVVRSSSYDHFTIELVDTQAVVAMSGEDWRSTLSSKEPTPLHLLQPTTLHVDLLKCLLTDDPNLAKVKVNVSLPNVTLSIVDERLLQLAYIAHSIPQPEQPEQEEDEEEHFDQDTDLNMNVILEDAAIARLEKVKLNPDGQQQDTPQFTKLELSFSLKETSLELKRATGKTYQPLMKLSALSTSVEVVQRTFDLTASVILGGVLVQHLDGCDRWLLSTPLAEGSSEEALLTIKFTQVDPKCPEFESKHASTLQLLCVDVTNLTAQLEQTAILSIIAFAEQLSNKLGEVAPTQPTEEKAALEPLQKVGDEMLDKKTQSKPLGKLKRKSLVKGKKKDIKEITTLRVLARLGRVSVVIGLANRDVAQVEVAGLVANIMMQGKDITISSRLKDFTVIDPGSEALHPKIVEVMDAEAWDANVKVYGEATEGHNYLDMNRVNTSVALTFGCARIVFLNKFIKDVLSWINTFQSAKDAVASASVAAAAAAQARMQEAYQECSRVSLALTLRAPLILIPQDSHSLSGLMVDLGEISIRNKFVLGEDRNELGYPSIFDEMTLELYNVKVSRVVLSVTGVAEQEHGLLQPISLDISVKRNLTISWYKKKPELEIQAMLKPIKMVLSEEDLRVTLKVLQDNLGEQGDVSLSEVNVPQVDREITENAQDVEMFLAQHGHRYTKIRFTFTIESVTLSLLTSAQGTKESLLSEDESMESLTSSSFKELSPQPGTSDALALPRVSLGDTRGSRRSLPHVTGDVAMQESGSVAHGRELAEFSLKVVTLKGEMCSDGSLSANLVLFDCILQDTRPGQEGHITRMMRRKPQTGKNGMIDLTYRQGPSGDTFIDMRISGFVLLLHLPYLLRIQRFFTDNLPQKPQEPSPPPLAAPKAKDFKRQKSGISTIDMEKHTANLMTVRFRVEQPDIAIVKDVTTEDTHCIIMHAEVNGDLKTTASQQSVNASITKIQMYTCCYNPSRRKETLSQILNPCEIGLVSYSTPSHAQHLDVTISRVDLRVSPITIELLSSLTMALTALEEPVKAEVEEVKEWVDLWDPRPLDISQFDFLAVEEASEAFGVEPTEAVSPVKQGPGGELAVVAMECFLVTIETGSGTSPIPLIKFQSSVTLTASGFFSKKLNVNGDLSIELAYFNSRLAVWEPLLEPVEVVNRSAFPDHAPWSLHFEMSQEMGTNGPKSPGKSCPTSPIASPESDEVDFEELQVPLPATTISVTAKDSLHLTVTKTFMEVLTTLSKAFADAYKRNLTARDTHLAPYRIINQTGKNVSVAVRQSGFQVAAEGGENVEEVMVESGAEVDLFEIAPQTPKHKRVASLVADYQAVQDRSITFRIADLGCQCTIPVSRADKRYFQVEHTRGGEKWGLVAAISVESGCKIITLSSCVQITNHLDVTVEVYYMNERGNEVVHVVSLKPGEMASLPLHAVYTLTAELFFSVEGHSVCIIPFIWRDLQNSPDLVQELQCVPRDVDEYHSSPFFIAAIGDVEQILWQNTSRRTMTSALYKIYLKPKVVLHNLLPVPVSVEPPGTMCTNVLMPGASVQLTKAQLGMSYLNLQILNYQGCDWVCGKPLAEKPQELSVWTFESRGDIMGGPLQLDLGMMASAPGSTMTLNLYCPFWMVNKTGLMLTYRSDAPSNYVVHEEGNGEAVMFSFKSKAFFGKKKVTVKVEDSEFSEKFSLDVVGSSGSVSCKSPSRTYQVGVDIQLGNSGLTKIVVFTPFYKILNKAPFDLEVMEAEFPHAEWFTVLSGECIGWWPIGNGRRIHVRIRGTSEMTAALRYDQPLSTLLYIPNKYGGISAEVNLMDGGAMVQLDQFSEGMTPVLIINHLTNTTVSLWQHNNDNKKVHVKPQSIQHYTWSDPGGLLQLVWACGAGKITQHSLDKDERGQMNDDTVHWVVFLFGNQRCLLFTDEIEIASAALNAVESERINQELKFSLSSIDLSLVDDVRKKEVAYMSLASSGVVWEYRKIKGRKYRPFTQNQTNELEVCHNLYQAQLKTFSGGAPIQSHYVIRDNFEVDFESMKIFKPFHKNIRRTFQPGIWFELRTSPHQRQIHLKINSLQIDNQMTDVMFPVVLARVPTPRSVMAETVAKPFCEVSIVQRLTSPSFSQYKYLAMLIQEFHIKVELPFVYAVLEVLFPSNDVSDNLYSMEEFEEDNKLVRETLTMRAQSQAISGQKDYYDLLHLSPIKMHLSFSLSGSESGASLPVGGQVIHLFLESVGVTLTEVQDVVFRLSYMERQNKWMTWGQLTQEMISHYRGQFLMQLFKVVLGLDVIGNPYGLVVGLTHGVESLFYEPIQGAIEGPGEFAEGMLYGLTNFMGATVGGAAGAVSRITGTIGKGVAALTLDDDYQRRRREAMHRKPADGIESLARGGKGMVTGVFDGVTGVFLKPIEGAKKEGVEGFFKGMGKGMVGLVTRPASGVIDFASGSFDAVMRATEAGEETVSRRRPSRFIGPDNVVRPYVQHFAEGAKLLRELEKGRYAETDVYVGHAILTENRSMLIATDKRIMCITRNDILGHWKVDWLHVYEDLSEPPFITPKGLRLSVRQEKKRVLGVFGGGDNSKLVPLKDPEEGKAFLTAVIEAYQKTNCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PV12</accession>
    <name>A0A3R7PV12_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Receptor ligand binding region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000688">
        <property type="protein sequence ID" value="ROT83415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PV12"/>
    <dbReference type="OrthoDB" id="10012363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="725"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="776" mass="85175" checksum="DECE9C9BC056B1CE" modified="2019-04-10" version="1">MPLRSHPHTDPLPRRPTFLTTRPPGHFRRVVKITCGFSLLLVLYQPPSFTPSSFRLPEDGQDEQLVADDAEGGHLQRWAVRVSAGVIGLLLMAAAGMLLRAVDHRYPASRLWAASSGAKLSIGVLLTDTPLDKDLLRAALRAAREQHSASARLSDIHVKQAQTHGTALGAIDAFKKLWNEGVKIFLIGGENSDILRALCKHIESSGHAGLLVSPEAMVSRDVCPCLVSLSPAQEAVVVVEAGRFLEAKVSHVVPVVTTSEAGQLTHLVEAAEARNLSVTPAVLLDPQHISLAQLKERLAEYPNAGVWISLGSDLPHLFAEMSYLVCGRLVMIHAHAAQRARLLRHPLAREAAEKCGVCSAAWAGSTRVDTSARRRLLDDLQPEDPLFASLAYDITGLALAALTVGRDASLPELRAQLLNHDSLNGVTGSMKDGRRSGWVARLRLVAQRLVGWAVLQDTPWLLEGSTQVASEDEGPWATVQETHAPTHMVTQEEILDIINRGRCNRSARVEVTAHDPLTHRAVTTSWSPAEAPYLLLIPNGSPNGFTIKAWCHERDGIPSIEVGCHGASKHSEALVCAFATMDRGRRVVRSILTKHVFPFRRQQYHRQKAYQEQINRRQDYYQLQGQQHYEQHGQQQGYHEQQQQGYHEQQQPATTATAGYTSSNSRATTSSNSRATTSSSSRATTSSNSRATTSSNSRATTSSNGKVMSISITRTNSISIKIINSHNISNKTTRKTKRNSTNRKRKNRKNRRSKTRPKCKQTVPSAAVLSAKLSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PV19</accession>
    <name>A0A3R7PV19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023388</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000686">
        <property type="protein sequence ID" value="ROT83432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PV19"/>
    <dbReference type="STRING" id="6689.A0A3R7PV19"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000006">
        <property type="entry name" value="DnaJ subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="52073" checksum="89070B9EED7B5196" modified="2019-04-10" version="1">MVKIEQPSELEDMISRVLGDGLEGLVLKKANGEYEPGKRHWLKIKKDSIYGGAMADTLDLVVLGSWYGTGKNKGKLSVFLMGCYDKRSEAWRTVAKEDGQRLLQDPRPVKDASEGDIKRAYRNMALKYHPDKNKSNDAEEKFKLVAEAYEVLSDKKKRNIYDQYGDEGLKGGMPGGRSTGGTHFTYTYSGDPRATFEQVFGTNNPFSHFFNMGVDGHGTHDVFEDMLVGGGSHVGVKTRRTFSFNPHDNNPFSRFFNMDVDGLDGDPPRFRENKGRNQDSAVIRDLYVSLEEVFTGVTKKRKITRNVLLTADGRSTLREEKILTIEVKPGWKEGTKIIFEKEGDQSPGKIPADIIFIIRDKPHPLFKRDGANLVYTAKIPLRDALRGTLVSVPTLTGQRVALNFNKETTKPQTTRRLQGYGLPYPKNPTRKGDIIVHFDIQFPLNFSESTKAHVLKSLYLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVU5</accession>
    <name>A0A3R7PVU5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-actin monooxygenase</fullName>
            <ecNumber evidence="4">1.14.13.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_002655</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-methionyl-[F-actin] + NADPH + O2 + H(+) = L-methionyl-(R)-S-oxide-[F-actin] + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:51308"/>
            <dbReference type="Rhea" id="RHEA-COMP:12953"/>
            <dbReference type="Rhea" id="RHEA-COMP:12956"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.225"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mical family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.225" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001350">
        <property type="protein sequence ID" value="ROT78643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVU5"/>
    <dbReference type="STRING" id="6689.A0A3R7PVU5"/>
    <dbReference type="OrthoDB" id="20799at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120501">
        <property type="term" value="F:F-actin monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000004">
        <property type="entry name" value="protein-methionine sulfoxide oxidase MICAL2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050540">
        <property type="entry name" value="F-actin_Monoox_Mical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057494">
        <property type="entry name" value="Rossman_Mical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23167:SF54">
        <property type="entry name" value="[F-ACTIN]-MONOOXYGENASE MICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23167">
        <property type="entry name" value="CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25413">
        <property type="entry name" value="Rossman_Mical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0440">LIM domain</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="FAD-binding" evidence="16">
        <location>
            <begin position="241"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="[F-actin]-monooxygenase MICAL1-3-like Rossman" evidence="17">
        <location>
            <begin position="393"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF25413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT78643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="672" mass="75233" checksum="67F61DC429478B34" modified="2019-04-10" version="1">MAVCLAFPLSFSLPPPFLPSFLPLLFSSFTPPPSFFLPFLLPLIFSSLSPPLLPEAKKGGGGRQGPPPCSCLALPVIGGGVAAATGSPLCQRVSQQLLRGRLSLRNRSGESVVHAGWCTTHTRRPRSLFSSVAPPGITVDTMYNSGHHHHHHKQGAPVSPDSAAAADVFEQLCTASTFKSVLYHYRLLCDVLRLKPTNFRNFYPKLKSKLRSWKAQAIWSKFDKRSSHKCYNHGKACTNSKVLIIGAGPCGLRTAIEAQLLGAKVVVVEKRDRFSRNNVLHLWPFVINDLKQLGAKKFYGKFCAGAIDHISIRQLQCILLKVALLLGVEIYENVSFEELTEPPEDQNEKIGWRARLSPADHPANQYEFDVLIGADGKRNTLHGFKRKEFRGKLAIAITANFINKRTELEARVQEISGVAFIFNQKFFKELYAATGIDLENIVYYKDETHYFVMTAKKQSLIEKGVILRDLQDTQQLLHPSNVDRNALMEYAREAADFSTSYQLPHLDFAVNHYGKPDVAMFDFTSMFAAENACRMVEKRGHKLLSGLVGDSLLEPFWPTGSGCARGFLSSFDACWMIRSFSSGKMMPLEVLAERESIYRLLAQTTPENLSKDHSSYSLDPASRYPTINLRAVLPFQVRTLFNTDDPVHLEEITNPHLVNNDELPKKRKRRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWR1</accession>
    <name>A0A3R7PWR1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative spindle assembly abnormal protein 6-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001764</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001233">
        <property type="protein sequence ID" value="ROT79500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWR1"/>
    <dbReference type="STRING" id="6689.A0A3R7PWR1"/>
    <dbReference type="OrthoDB" id="49058at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007099">
        <property type="term" value="P:centriole replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10142">
        <property type="entry name" value="HD_SAS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.20">
        <property type="entry name" value="Spindle assembly abnormal protein 6, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032396">
        <property type="entry name" value="SAS-6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038558">
        <property type="entry name" value="SAS-6_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44281">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44281:SF2">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16531">
        <property type="entry name" value="SAS-6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle assembly abnormal protein 6 N-terminal" evidence="8">
        <location>
            <begin position="38"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="626"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="165"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="252"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="350"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="434"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="585"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="644"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="654"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="693" mass="77327" checksum="B740E4CA44EB772E" modified="2019-04-10" version="1">MEILGGKSGGEVLANCEVCIKFIEAGCAVAAATFRRLRLLVELRGRSSGTSKELLVRLTDDSDPFFLFTCIVCEEDYHSLRQSQGLLIDFSAFPHKFVELVNTCIRESDKDSPKFVLALRCSDSGGDHAALEVVEVNIFKHLCHLSLTLTPASTQLKLSHLAECCKALKAEVKFKEREAEENAKELEHQLRSTQDILAKTSREAQELRSELNHQIALSSEKQAQLINQEKDKLLKVQSDADRRADRERRDLEAKMSHRIDQLQAKVSSLTAQNSELMEKKQRAEGSVKELRSRLSSAEGNLERCRQELGHTKKINAHLDKDYHSKSSAVRDLESRVSHLEGELRSKDTSLGHTQEMLESLQQQKRSLEEAVEEKQQKLAKRENSIQMLYAELQKSLDVIKKLQKKIKEEHMTSNVRGAALMEQDKLVTEKDSKVAELSEQVQQMATKLSQLTLDNEKLQSENREAKEKLLEHEKTLETNEKVISWLNKQLNETEIAGAVIKRAPLTEAYLTSQSHGVQGPRFPPTGLPAELAHSTPLSNTLRSLPTVSSSGRSAGGHSTMSSLRTFGHIPPIPEEISPRTSHVSPTEKDISPVDKENMQGLDPKYFEPTGVSAVQVHGLLRANYQRTTHRDTGSQPKVSVADGKQGERREGRGGRGGATRGGRGRGLGERKVTDATRKFGTSTSRASNYFPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWW5</accession>
    <name>A0A3R7PWW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Carboxypeptidase a1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_020158</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003863">
        <property type="protein sequence ID" value="ROT62033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWW5"/>
    <dbReference type="STRING" id="6689.A0A3R7PWW5"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF89">
        <property type="entry name" value="PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="193"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="115"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="603" mass="67486" checksum="D61A887079F896EC" modified="2019-04-10" version="1">MCSSLPFSPPPCCCFPRLRPPPRPAPSPGSKGSSSAGAEGPQVDPRSQDYVGWKLLRIFPSSRPLLTALVASLRNSSQAVVVQVSQEELLADVGLPPKASLEGVLSSALPSPLPPLRSLDAPDAAHVTPGREDQPRAEKKLDECQGAESPAGEVSLTRSKRRFSLDFLNWKTLPGFVEEKAKLDGSEPLAWDDYYRYDSIRRFALNLSASLPHVEYLDIGRSFEGRPLFALCFASKASDMKKLFKKKLLKLRRLRTKRGRDPDLAVLQKRNLVTRKRKTSKPYVLIEAATAILPPPSPFGHSNRSPLWLPFFIRIFLLCDLFPLPPLLLFPPSPSLILASFQFSIHAREWIAPAVATYLAQELATLGRKFLKRVTVILAPLTNPDGYEYTHTTDRYWRKNRRTTPTPSCPGVDLNRNWGVGWGDPEGSSGDPCSEVYRGPESFSEPETQALRDLALVWMEKIRLYVSLHCMGRVILHPWGFTRAPSTKQRQLARIAKVMAKHLHRNNQTFVFGQTSHVMYTASGTVEDYMHGAGVKYAYTLELPEDSFELEPEKIIPISKAVWNTFLCTLGEIIKTDGIRSFCKTEKATGKLRKKPATKRKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PX37</accession>
    <name>A0A3R7PX37_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative eukaryotic translation initiation factor 4 gamma 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003764">
        <property type="protein sequence ID" value="ROT62213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PX37"/>
    <dbReference type="STRING" id="6689.A0A3R7PX37"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11559">
        <property type="entry name" value="W2_eIF4G1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="12885" checksum="1FDAD275CF910012" modified="2019-04-10" version="1">MVTEREQELLAKFKPVLQAFLHDHLPLQVTAIYALQVFTYTNNFPKGMLLRWFVNLYDLEIVEEDAFLTWKEDLSQDYPGKGKALFQVNQWLTWLQETEEDDEEDDGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXA5</accession>
    <name>A0A3R7PXA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial import inner membrane translocase subunit Tim17-B-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_010467</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000233">
        <property type="protein sequence ID" value="ROT85606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXA5"/>
    <dbReference type="STRING" id="6689.A0A3R7PXA5"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT85606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="171" mass="18007" checksum="6E66DD0AAB719F2C" modified="2019-04-10" version="1">MEEYSREPCPWRIVDDCGGAFTMGVIGGGLFQAIKGFRNAPSVSLSRRFTGSLVAVKQRAPIVGGQFAVWGGLFSTIDCSLVYMRKKEDPWNSIISGAATGGILAARNGVATMAGSAVIGGVLLAMIEGVGILLTRFTSEQFKPVAPGEMADPSVLGPPQPLSLNQDPNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3Y4</accession>
    <name>A0A3R7Q3Y4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative fez family zinc finger protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_013875</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000273">
        <property type="protein sequence ID" value="ROT85452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3Y4"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24390:SF159">
        <property type="entry name" value="GROWTH FACTOR INDEPENDENT 1 TRANSCRIPTIONAL REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24390">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018713976" evidence="9">
        <location>
            <begin position="26"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT85452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="237" mass="26777" checksum="8750231A8A6FD6BC" modified="2019-04-10" version="1">MVSAFLCKLLHSLCWEAIGIGSGRSFMVGLGVCAPRKGGDFTLACSSGSFSKPRIQERSRPRHCHLPVAAGNILSNPPASSGRRRKNAHCHLCDKRFESRYKLKMHVNTHTGARPFTCDVCGKGFMRRTTLNAHRTIHDASQFSCPTCNRPFKRSSERLIHILLKVCLRKQRILRRTTSGWFCDVCNEGVPQPEEHRCPVKGRRRQCPVCGMDFGGQRDHKMLTHVRQDHPEFLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q416</accession>
    <name>A0A3R7Q416_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000257">
        <property type="protein sequence ID" value="ROT85533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q416"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018782280" evidence="1">
        <location>
            <begin position="48"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="42610" checksum="E8D88DD156367C3B" modified="2019-04-10" version="1">MPLAFAWSSSVRFVGASLPSCRRSVPRRWALLARVLLVLRLQTKTHAQSHVHANKWTHPPPWPPYPAAYPLPAPAYPPLPLLLPPSHSPSLLPSLSHSPFFTRIFFFFTPLTGAPSLLRPPFLFTGRGVRSPLKLFVYGLCLRCVTPPVPRAECARRSRPRLAAPGECLGCLAALALVTCACCTFRGSSVLYVLLLAVWFFRSFSRFPSLFFSTLPSSSLHSSFPSHPILSLPFPSFLSFFPSIPPSLSSLSLSFSSLLLSLLPLFCFVLREGSKRGPLFLPGRWEVLVFTPFLPPLLLPPFPFPPFLLSSSPAILPLLPLSPPSQCRVQAESESSLTEAARAPLFTFRLPGAMNPAPATCPGRCAPPTCPRPRRLRAARVLSRPCAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9Y1</accession>
    <name>A0A3R7Q9Y1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002160">
        <property type="protein sequence ID" value="ROT72410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9Y1"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="27542" checksum="8688DAB46A7DDC39" modified="2019-04-10" version="1">MSTLVRVHPGPALWTRRQAGHLASPTRQSRDSFTWNNTYVDAPRKKVFVLLQPELGAMQHWVALLLVAGSSVSILARPQFGRFGGFQQGGSGAGYGGANVGFSGSTSNKPGSGSSISSSNKPRRDADSKSGACDICSGGSGVQVGGSGGATGGAGDGAHGEESEAAEEPQEELVMEVHGEDKSEAAEEPQEELVMGAHGEGKSVGVGEPQEELVMEAHGEVSLEAAEEPQEELVMGLIWRTSGGATGGASDGGEDKSGQRRSHRGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBU0</accession>
    <name>A0A3R7QBU0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ets DNA-binding protein pokkuri</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_019358</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003553">
        <property type="protein sequence ID" value="ROT62775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBU0"/>
    <dbReference type="STRING" id="6689.A0A3R7QBU0"/>
    <dbReference type="OrthoDB" id="6408625at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000516">
        <property type="entry name" value="ets DNA-binding protein pokkuri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000061">
        <property type="entry name" value="Ets DNA-binding protein pokkuri"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003118">
        <property type="entry name" value="Pointed_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF201">
        <property type="entry name" value="ETS DNA-BINDING PROTEIN POKKURI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02198">
        <property type="entry name" value="SAM_PNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00251">
        <property type="entry name" value="SAM_PNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00345">
        <property type="entry name" value="ETS_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00346">
        <property type="entry name" value="ETS_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51433">
        <property type="entry name" value="PNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNT" evidence="6">
        <location>
            <begin position="102"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="ETS" evidence="5">
        <location>
            <begin position="246"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="348"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="48121" checksum="2C9FADAB2AB89A26" modified="2019-04-10" version="1">MKVPPLNLTPDINRVGMALPFSPDLLWRYPLSLPQSASPSSPMLDVKNQMPTHLGEWLRGFQRRDLFFGGDFEDYENFVFIRVCGLGEIFVWLVDLVFEERVVPFVFLFGFVDLCCAADPRMWSREDVAAFLRWFEREFELPTIDLSKFCMNGKALCMLNKSDLADRAPGAGDILHNTLQFLLRDAPQPLPPPGRLRSAHSGSQSDSEDSTRDSSSPQRSPLPPTSAAGMSTGPNEEPVETGTNGRLLWDFLQQLLNDSQQRYSRYIAWKNRETGVFKIVDPPGLARLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPSELKSIKNISMLRTTPLQSPRAKDAPTPVQPAPMEEEEGPTDLSMASLHHQYHAPPPAPMETTQVQDLSREAHNLSVSIKSEEYLEQSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCK9</accession>
    <name>A0A3R7QCK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein APCDD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006983</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001885">
        <property type="protein sequence ID" value="ROT74506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCK9"/>
    <dbReference type="OrthoDB" id="5985602at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017147">
        <property type="term" value="F:Wnt-protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042425">
        <property type="entry name" value="APCDD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029405">
        <property type="entry name" value="APCDD1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31021">
        <property type="entry name" value="ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31021:SF1">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_56, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14921">
        <property type="entry name" value="APCDDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01352">
        <property type="entry name" value="APCDDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="APCDD1" evidence="6">
        <location>
            <begin position="36"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="277" mass="30179" checksum="23FF27C84977CF9E" modified="2019-04-10" version="1">MTSTAYAIDEMTSSIYTRDVVTSSIHARDVVSDCAVCGLVGRSNERSPAHLHAGPELPLLLAGSWASHRCETRPYGMFLTRHIAFSPTDNDWKMTLRYYHDPECSRPSFTLAAHGSYARAAPSPYAYDFHVTRMVLTPDDADLANALNSYKGKECGRPGSWETGKPQDITPTGGCQAVGVRVPVVEKEILRSGVDENGGMWLALGQTATTPLQVGGLARPTSWGPQLIRCRHYSPRDIDNNLQPMVGARTAYSAAHDHAQPLFSIVVLCLLVAIRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QDZ7</accession>
    <name>A0A3R7QDZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005788</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001747">
        <property type="protein sequence ID" value="ROT75682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QDZ7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="831"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="731"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="859"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1142" mass="122150" checksum="3DE9B7D54F06D992" modified="2019-04-10" version="1">MTNTLTQDPLRRRLQKPHQRRQVVRNLDHESLFAGDLDFGFAKRLSEESEPVSDGRRVVGHPRVTQFLLSLSTPTLSPTHPFSPSSHSTSPSLLLPSSLSSPPSLHFFPSYPSPSPFHPPSLSPSPFPLPLPPSPPSPLSLPIPPFCSPPHSLTPFPYPTLSPPPYPTLSSPSPHPYLPYPHSPLPHPNSSLPLPHTSSPSPHSLLPLPTPPSVPYPTLSLSSPYSSPHTHSPRLPTYPITLLSPLSPLPPLAHTPHLPHPHPPALPLHSPPSPLPHTLPQALSPSPTLPHPLTHSPPSLTSPTLLASHSPLPLTQHSPLPPLTHSLSLPPPTPHSSLPPFSLTPLALPLPLPSLPLPTSLPFPNTHPSLPSPSTPTNLRQLDGKSHSPPPLTKPHSPPSPYLHSPPPPPPPTFATRRRTPTWRGCLHQRRQLSPQLHPSSPFPPLPPHSPLPPLTPHFPLPHPLPPLPPSPHSPPSLTHTPSPLPHPHSPPSLPPSPPPTTFANSTENSHMARLSSTSVASACSVFSPQLHQHSPLPPLPTLSPPSPYPTLPLPPSPFPLTLSLPPLTPTLPLPHPTPSPPSLTHSLPPYPTLPHTPLPPPLPSSPYPTSPLPHPTPPLPSPPPSPTNLRQLDGELPHGEAVLHQRRQRLLRVSPQLTSIPLSLPLPHTLPSLPLPTLPSPSPHSPPSLTPHSPLPPLSLHPTNLRQLDGELPHGEAVLHQRRQRPLRVSPQLHQHSPSLPLPHTLPPSPLPHTSLSLTPLPSLPYSPLPFPLPLPPPSPLPPPPPTFANSTENSHMARLSSTSVASACSVSRPNSTSIPLLLTHTLPPSPYPTLPSPSPPLPPLSLHPPTPPQPSPTRRRTPTWRAVLHQRRSACSVSRPNSTSISLPLPTLSPPPLTPHSLSLTPLLPSLPHPTPLPPLTLPLPPSPHSLPFPHTPSPLPPLPSPPLPPLSPPHQPSPTRRRNSHMARLSPPASPAPAPCLAPTPPIPLSLPLPHTLPFPLPTLPSPLTPLPSPPSSPHSPPIPIPLSLPSLTPLPPLPHTPSPLPHTPSPPLLPSPHPHNLRQLDGELPHGEAVLHQRRQRLLRVSPQLHQHLSAGRVHVREILVLVRGGVLLQEGFSPHLEESLAQLRGGGGNGGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE55</accession>
    <name>A0A3R7QE55_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001721">
        <property type="protein sequence ID" value="ROT75864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE55"/>
    <dbReference type="SMR" id="A0A3R7QE55"/>
    <dbReference type="STRING" id="6689.A0A3R7QE55"/>
    <dbReference type="OrthoDB" id="3246549at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="145"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="178"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="679"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1147" mass="126964" checksum="4FB50E625851F3A5" modified="2019-04-10" version="1">MSETEATRRLASAVEAGDEEAVSAALQEGADCDSLCPPDDPECRGGTLLFKAVVRGHAHLVPVLMRAGVDVNGRGQVGYTALHVAAACGGSSMIPSLAKGGADVDCMSSGGFAFSPMHMAAYRGDEAGIAALLASGANIDVCTPRRFTPLHTAAQYGHDHLVTLLIESGCDRHARSSTGMTALHMAAMQGLKSTAKLLLKYGLDPNARDENGHTPDNCADVWGMNDIRWWFLKLQDSNPTSIPRRKLHANSQEVYEYDHGSLSSNVRLQEWFTLKDVIPRTRDGHYQDSRGHTLLHLAAALGHQKTAEVLIEMCGVYPGVLTHRGQTADELARQNGHFQVAEALIQARKRDETGKTPEELYGELLSAISTGDDVKKASALVKAGAPLEPTGEYSTHSLVLAVTSNRPRMVSFLLAAGASVNITFHRLNLVQVAWLSPDVTAMVSMLITRHMENVLQEEKTLCEATELRDGIDFLLDALRSRTPWKAAWPAQSSGKPQQQQLLTSLMVEAARANCSLTALFLQQAGALAHGHDVCSGMSPMAAAVQEGHQRLIHFMAKTTASLYIRDTTGQLPRDSLSPSQRQELEKMIYEQEMRVLNHQKEKTKDEEEKELFRRIQDLHRDLYQRHLIPGVTPSETPMSEKDIVRRTLLVASQLGLVQLPFILITKGVISVNEEADPITGTTALHQAAAYGHKNLVALLLNLGADLTLKDTGGHTPAHLAAMFGYSLANKQLWSLQMREKLICRAGTTPSDICRNFGLYLKKYRKSGEINELPDTNDPQMVFQNHFQSLTLSKLIEMTAEDSVNFSSGEAAEVKDAVMAELEVIKGKVAEKNPMFNGSLKLLGSSRDNTRLFAPDEFDVNLVISHLPEVKVEICEFPKPKAIATGHKLCIKVGSEDPDFEKKLRATVWKDTFYNLTYEALKHHRFRDPRLSLVPPGVTRTQVGAAIQMAWQGSECPLLLISVDLVPVIATPWPPDFPKPYLTPAQAEKETLGITNIDDSQWRFSFAETEAVVLQGLSPEERRVYMTCKTLLYTFKAERWMPREVKNRYSWWDCRPWKIATPPGFALKNCFFRRLEDKRRRGEKWEEGALVSLMADVFRLMCHRFQNGADEADSLVPSKVPAYFGGDFESPKVGFGAVQIVKFLESIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJE5</accession>
    <name>A0A3R7QJE5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Carboxylic ester hydrolase</fullName>
            <ecNumber evidence="6">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01001076">
        <property type="protein sequence ID" value="ROT80740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJE5"/>
    <dbReference type="STRING" id="6689.A0A3R7QJE5"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="7">
        <location>
            <begin position="6"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="7">
        <location>
            <begin position="189"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="53437" checksum="F7CCBE719F26220F" modified="2019-04-10" version="1">MQQKHMREYRMSEDCLTLNIYTPLPESRRRRTNASELPVLVYIHGGSFYSNGGRLYPGEKLASEGIVVVTINYRLGPFGFLSTGDGWSRGNWGLLDQRMALLWVRRHASAFGGHKDKILLVGNSAGAASVILHLVSPLSQDLFSRAAALSGCALAPWSLQSRPLHFAQQLAAGMECPVSPSSELDGLWLAFAPVVEGDFEGAFLPRSPRTLLEEGSLPPIPLIMTLTKDEISIWFREASPSTLSPSSENRTIELSRAEDWMDIIMKQKFPDLEPRALAAVLHAVRAAYIYRNGYTTKVPVKIISELISDLGLRVPCVEEAGLLSHWTRLYFAEFSYVSPDDVRVGSQKWIGSYHESDLQFVFGQPFLGLANTLRGPKDRSVATTIMSVIISFAHTGVPELGEMEWPAYNLSHLVHLELSEQLSLSHNLVQHSLCFWQRFIPLLTLFPMKPPEEEPNAAPPFATPPVSLLLLSSFLHRAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKL6</accession>
    <name>A0A3R7QKL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002430">
        <property type="protein sequence ID" value="ROT70416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKL6"/>
    <dbReference type="OrthoDB" id="412780at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="30088" checksum="9408972FB124ED33" modified="2019-04-10" version="1">MIVVTVILIFLIFLMSGIYQEMLRREALLLNATQSNASLYLADDFDDAWLGEFVNKNLTLNLNNTSGSNETSESVQIKVIIQPDWEVVEGTFEHFKDENFEALLIAVGVPFVVRNMIVGTTPTVHIEHVQKGDDYYYDIEGDYLADEDQAEVPEPEYQLLITTSTWMRSSEERVRPGYSFHKTDYDGSPSKNTYKFVSPRVLLHRKEKEKMNTDIIRKFDEEGFVMVQLRMGFLQDKLFIIADILDGLLFQICGSVRIGFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLN8</accession>
    <name>A0A3R7QLN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLN8"/>
    <dbReference type="OrthoDB" id="6330989at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT71395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="207" mass="23242" checksum="4403E19CF2A48B10" modified="2019-04-10" version="1">MSDAEDIDYFVLGFEDFDESARLLEDDFFQREPLVGLLLFTCGTFQDSKKKYWLNVSCFLFMKVAAACRIELHNTTDLIDMMDAKAFEYFLLKPENQDEVAKLIEEDYFPREPLCRGFHVTASASSGMTSRKLRECLASGVSFGARDVSTGALAGVRLSYTKAKAEAGSAKPLGERKTEYEIKVCGLCDEIRSKVNIFEESDAEAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SKY0</accession>
    <name>A0A3R7SKY0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Integrin alpha 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the integrin alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003118">
        <property type="protein sequence ID" value="ROT65225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SKY0"/>
    <dbReference type="STRING" id="6689.A0A3R7SKY0"/>
    <dbReference type="OrthoDB" id="6362691at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000413">
        <property type="entry name" value="Integrin_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220">
        <property type="entry name" value="INTEGRIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220:SF83">
        <property type="entry name" value="INTEGRIN ALPHA-PS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01185">
        <property type="entry name" value="INTEGRINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 6" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018376379" evidence="5">
        <location>
            <begin position="20"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="4">
        <location>
            <begin position="31"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="4">
        <location>
            <begin position="330"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="4">
        <location>
            <begin position="398"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="4">
        <location>
            <begin position="458"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="559" mass="61173" checksum="11489998E32150AD" modified="2019-04-10" version="1">MKAMQSVIVALVLASLTSAFNLEPRESIILSDTARGQVPGGRESYFGFSVALHYLARENEAWLAVGAPRANSSYYNPDHITEPGAIYKCNLRSQECEELFIDDEGNTGARAPSSEFRYMDLKNGGWLGGALDSQPTYQAGRQSLGVCAPRWKNQLYQGTYLMNGACYWLNSSLPNEPAHKKLPLIQFSKQTFPIGGRRLFFYSHGGAGLSVHFSDNPTEMIVGAPGVFNWQGTVIRFKDAGLPPIGEISRRRRRRRQTLVSEHQMFSSQFVPNPYYTSSIKDFDLLGYSVTSGHFLSPDEIHYAAGATRGGNSLGKVLLFSFPPVEEMRLYVIYEWVGTQIGENFGASLVSADVNGDGLSDLVVGAPMFFTADASDMGKVVVYETSVQQGETTIEKSERRYHGSAKAGARFGTTLAACGDLNQDGFQDIAVGAPWEDGHGAVYIYLGSPQGLRSRFSQHLLPQDFSAPFSGFGMSISRGIDIDQNGYPDLAIGSFLSGHAVVLRSRPVVDVRATVSSRPTSVALNATSLQLVVCFDHSGYNVPSQIGEMEEPEEFIVWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SL76</accession>
    <name>A0A3R7SL76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016493</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003077">
        <property type="protein sequence ID" value="ROT65531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SL76"/>
    <dbReference type="SMR" id="A0A3R7SL76"/>
    <dbReference type="STRING" id="6689.A0A3R7SL76"/>
    <dbReference type="OrthoDB" id="3800937at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051764">
        <property type="term" value="P:actin crosslink formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030838">
        <property type="term" value="P:positive regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11779">
        <property type="entry name" value="SH3_Irsp53_BAIAP2L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013606">
        <property type="entry name" value="I-BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027681">
        <property type="entry name" value="IRSp53/IRTKS/Pinkbar"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14206">
        <property type="entry name" value="BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14206:SF7">
        <property type="entry name" value="INSULIN RECEPTOR SUBSTRATE 53 KDA, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08397">
        <property type="entry name" value="IMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51338">
        <property type="entry name" value="IMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="IMD" evidence="5">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="167"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="265"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="400"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="602"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="664"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="753"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="443"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="666"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="709"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="777"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="787"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="815"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="918" mass="101051" checksum="3AB36B7BAA045790" modified="2019-04-10" version="1">MNLRNEPEQVTALGEEHQRVWAPAVTQERRRYGFILERQCSLAKHYLAYHGKGSSLLQHTLDKWQEVSKTRETLPDRIQCMLPTSRPRDTEGIYSTPLCLDDDAMSVTSQMRKARSVDASCLDLSSIVDEMPSRPITRARSEFNLDHRTTPDTLMHRRSMAVPEDSSRRAMARALYPYSPSGDNQLSFVEMDLIALIGEKNKGWQYGENLRTQRCGWFPVAYTELLHEEDDSALGFPPWRLYHKNHISTGDLCLIPPPSSPLLHGCSSTMASQLNSRGSVEDPQPTPAGAEEPPAGPGLSQHAHAQPYHRFPSKHRPSIASMTQVSWLESLPQVRAASPAAASHASASTSASSVPVPQSSSSAKSSHVASSQETLRTCTSMSSSVNTVLFNHAILEPPSARVSAPTIKKSTSQPQPHAKAGSNPFTSSGSLTTGSSMTLSRSFTTGAGSSHLSTRFQKRGSGNASFHSSDDSGFSNESGSIRPPMNPEADYSDDDLNGLVPHSMNSLSSRWLRSSTTPPFNTEPVSLPCLLSPESCHSSDQQSFQYIAGDQDATMTLPTPGRKSKSDSVKHRDLSLPSLSIDHFVTLARRKTTRASPCAQKIAAQRERGRSQERGRRTVRRSSSLLCLGMDSCRGIPDDLQSADYEDVWSEDWRHSSLVDVSLDIPDPPSFQPPAPPTPASTRPTVDYSIRPPMPLPHDDPNPSPRSCSNTRQSESSQQNSNSSSGNSTLTGSDEEDNEEEIYMVVSDHRCEMRKTQMRKQVSRSLTWASPAHRRSPPPPPLPMSNPPSSAASSTSTKVTQIRRSHASPRRPDASQPSSAPHSTPPSQAAETPPLPPRRTQRPPCPLPKESRRQPVDRLLMPWQYGSEVNILNYSDYMNRRLKYPEGVSRIDQQSFTTGNLCGPWYDLWADDPSVADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMN4</accession>
    <name>A0A3R7SMN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_014378</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002801">
        <property type="protein sequence ID" value="ROT67556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMN4"/>
    <dbReference type="OrthoDB" id="6353409at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF38">
        <property type="entry name" value="IONOTROPIC RECEPTOR 100A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018680511" evidence="11">
        <location>
            <begin position="34"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="640"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="12">
        <location>
            <begin position="359"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="591"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="612"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT67556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="666" mass="73747" checksum="42FC330E0D102FC0" modified="2019-04-10" version="1">MSAWCKKPRDGGRKWWMKEISLWFIFTASVAHASQTAACEDFRPRAASAVLERASQPRSSFILITDGSAFSISLTKDLGERGAPGGVSVLTVAGDASANQTRINLLGVIQIGRQIQKASWRSTVVVASSDLLFLTVFAEAADEGRLVGSETRVLVVTSLALPEVRSLLGQSWVFSMCNAMLLNLPRDAADSRHNLFAHLPYGPTGPHLSRVASWTSASGLKFKSEVPLFPPKFDNFYGAPLNMTVHPFPPYWMEVESGRPDGSTVKRIAGRDYTMLETMAQALNFTISVMPDADWEEVILRVEQRRAFMSPMKLAIMPHLLKLYDFTTVIEPATLGFSMAKPTLKPRWQSLYYPLTDGVWASILAVLALVPVALILITKAGARMGSQSIRSMQRLVLEVAGSLVSQSSSGRGYDTSSTQVLLATWLIFSFIVSTAYRGNLTAFLTIPKYPDRPETLEQFIRTGAKATYPPDVVDFYNNFKKSDSYLYTTLASRMTLVPNFQVGLQEAIDLGQGYFYERMSLKLAIEEHFTSADGSTRLYVAGQNILPAYCAWPIPWGVPYKEKLNQFIMAFQAAGLIEKWTEDILKEARQESTAKQRRNANRKKEVQGTASDETDSDDDSEDSSSQGIMALTLTHLQGPIFLLLLGLLVSSLVFCVEILASWILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SP38</accession>
    <name>A0A3R7SP38_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012743</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SP38"/>
    <dbReference type="STRING" id="6689.A0A3R7SP38"/>
    <dbReference type="OrthoDB" id="6368475at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000033">
        <property type="entry name" value="Endoplasmic reticulum aminopeptidase 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="11">
        <location>
            <begin position="2"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="10">
        <location>
            <begin position="148"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="255" mass="29564" checksum="A117AC101E1E6465" modified="2019-04-10" version="1">MDEELIKGERYTLQMEFLGYLNDQLRGFYRSTYRDDDGTTKYLAVTHFQPTHARRAFPCFDEPALKATFEVHLARETWMTSLSNMPLARVEGQEGWVWDRFERSVPMSTYLVAFVVSDFSYIPSTSGKDTLFRIWAQPSAIRHAEYVSEVGSKILAFYESYFNVSYPLPKMDMVAVPDIAVRGMENWGLITMIDRSILYDPDVDSANHKDTLLEVVAHELAHQWFGNLVTPRWWDDLWLNEGFATFVAYIGSTYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STC7</accession>
    <name>A0A3R7STC7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_007349</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001928">
        <property type="protein sequence ID" value="ROT74155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STC7"/>
    <dbReference type="STRING" id="6689.A0A3R7STC7"/>
    <dbReference type="OrthoDB" id="19132at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042051">
        <property type="term" value="P:compound eye photoreceptor development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002009">
        <property type="term" value="P:morphogenesis of an epithelium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061061">
        <property type="term" value="P:muscle structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048477">
        <property type="term" value="P:oogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045466">
        <property type="term" value="P:R7 cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000091">
        <property type="entry name" value="Lola, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF82">
        <property type="entry name" value="PROTEIN TRAMTRACK, ALPHA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="182"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="521" mass="57987" checksum="48478EE8FCD8CADE" modified="2019-04-10" version="1">MRQRHVLELIGSTTSPRVFQPRFPLMRTFPYNTLISPHSHVHQPLRIDISSIFVLKPESPLPIHPTVGPTLLHLTICSSFYPPNQRSIRESKSQPFYPVTESNGVRAMHLSPPHPPHPPPSYPPLSPPSAHSPCLPRELKHDKVSSGVRMAMSPQQFCLRWNNHQSNIISVFEQLLQSESFVDVTLAVEGMTLKAHKVVLSACSPYFQAVLASHPDKHPIVILKDVRYTDMRDLLDFMYRGEVSVDQDNLSGFLRVAESLRIKGLTEVNEKKRLENSSSAYLMPQAMPGAAPPGVAPGVVPMAPLTPLPGDPPPLKRPPLSPSATYGAKRRRGRPPKISEPDDLSKEADTKVGREAIGERMSLLPCTPHHVAIALHSPFPLLPFHSLPSSSLVSLVSFILFSLFLNFSFLPVRRVSSTLSFTHSHSLISFFPSLSSRFTLFFLASKASFHSHFLTFLLLRFLQFLSLSLSLLALFLLSLSFSFPTSSIPSSSPPPPSPTLPPYLEPDHKHIFTHRTKQVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SV56</accession>
    <name>A0A3R7SV56_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">lysozyme</fullName>
            <ecNumber evidence="2">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001631">
        <property type="protein sequence ID" value="ROT76628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SV56"/>
    <dbReference type="OrthoDB" id="6337871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031640">
        <property type="term" value="P:killing of cells of another organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008597">
        <property type="entry name" value="Invert_lysozyme"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05497">
        <property type="entry name" value="Destabilase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51909">
        <property type="entry name" value="LYSOZYME_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="6"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="38"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608597-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="813" mass="87650" checksum="7FDF674D4C8B624E" modified="2019-04-10" version="1">MPENVCQNNGWGEVCGPWSITKPYWTDAYKPGGDYYTCVASWDCNEATVRAYLKTCRTLTLRVRPTHALMSVGHGASIRTTPRTTGISASEAATSSRIVGILGACRAATSSRMWGILGASRTATSSRIVGHPRRFWAATSSRIVEHPRRFWDGDVIPYRGASSALLGRHVIPYRGASSALLGRPRHPVLWGILGASGRATSSRIVGILSACRRRRHPALWASSALLGGHVIPYRGASSAILGRPRHPVSWASSALLGRPRHPVSWGILGDSGAATSSRIVAHPRRFWAVTSSRIVGHPRASRLRRHPVPWGILGASGRPRHPVSWGILGASGAATSSRIVGHPRRFWAATSSRIVGHPRRFWGGHVIPYRGASSALLGRRRHPVSWRILDASGAATSFRMVGHPRRFWGGHLIPYRGASSALLGRPRHPVSWGILGDSGAATSSRIVGHPRRFWAGHVIPYRGASSALLGQRRHPVSWGILGDSGAATSSRIVAHPRCFWAARHPVSWGILGACRAATSSRIMRHPRRFWSSDVILYRGASSALLGRPRHPVLWGILGASGAATSSRIVGYPRRVQGGDVIPYCGASSALLGRPRHPVSWGILGASGAATSSRIVGHPRRVQGGDVIPYRGASSTHLGRPRHPVSWGILGASGAATSSRIVGHPRRFWGGQFIPYLGASSALLGRPRHPVSWGILGASGAATSSRIVAHPRRFWGGDVIPYRGASSVLLGRRRHPVSWGIVGACRAATSSRIVRHPWRFWNRDVIPYRGASSAILGRPRHPVSWGFWGGHVIPYRGASGAATSSRIVGHPRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SW04</accession>
    <name>A0A3R7SW04_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaoptin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003231</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001440">
        <property type="protein sequence ID" value="ROT78067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SW04"/>
    <dbReference type="STRING" id="6689.A0A3R7SW04"/>
    <dbReference type="OrthoDB" id="1111193at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001164">
        <property type="entry name" value="GH01279p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1113" mass="127064" checksum="D87B6A88B11E8BA9" modified="2019-04-10" version="1">MGAHSDAYGALGNYISDLTTEDFDGYERSLQTLVLAENSLTILPEGIFRTLENLKTLNLRGNNIMTINPRAFQGSSSHLAHINLANNLLTTIPFEAMSEVRNIQTLNLARNMITQTYEVLYTGSLSMDTLVLDFNQIESLQPYSFQNFGNINRTSLRGNPLTHISEDAFKDAKIKELYLHDCDLWSISEKAFGGLESTLQLLELSYNNLSSIPEKAFDKLDALRSLSLSNNKMSLDPTEAFNGFRYTLQYLNLLGDNMGSIPMDKLKEMRNVRTLGLSTLPDKSLSKEDFRGFGPAMEKLYLMKNGISAISGHAFEHVPGVKILDLSNNNIGTIDNEAFVNIGSGLEELRLSSGLSMSQLPPQPMQYLTHLRELDLSNNNLQKVVGECFRNMRRLKKLNIQDNKIDSLSRNHFQGQYHPYLESIQLSFNSIKKIEPQTFHDYRNLKYLYLDDNQISKISRSGFSNLESLEHLDLEGNNIRHLEYEAFQNMPKLRYLDLSFNEMTNLNLDAFDQVGTLSSLTIDASHNRIPYLKLNGSTWNSYLSIKMIDYSHNNITWISRDYFESVRSSILHLWFHHNNLRNVSANVFGTFPHLQLLDFAHNRIEQIDHEAFRETRHIQYVNFRHNDISDLPTSLFENHQRLRHFDVSFNHLRGIPDSLFKTSPLEIFKARNNRFTKFPESSLHRCAETLRVVDLAYNQITSLTDSMMGRFDNMVSIDVSHNHIKTIEARAFRGTGRLVALDVSHNPIKDLPGFTFDGLQESLMNLSVANTSLSAVPDFDLPRLMHLNVSHNILSFLPSVTMANLSSIRVLDISYNELPVPANSAWQMLPRLRELYMQKNPIRSLTNTSFTGLERLEILDIRDFPLQVFEAGCFTSLTSLRRLYMTTHPQINRFNLARALHNVPSLQELILEVDGTLNSELMNYELPYRLTNITLMGPRMRKISPTALQEIRARELQLTFYRTHMEEVPRDVFKNLGRVKYVAVAAENNTMTKLGEPSTTGYPGVPNSVFLTDLRMHNNQWNCDCGIGWIEGWLKKWRQSVCVDNGRLEEYLRCQDTVHRLRQTPCNNKRKSIMEALKTDLECGSTAGASLVAPSPLLALLLVGVPLFLMGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYD3</accession>
    <name>A0A3R7SYD3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">DNA topoisomerase</fullName>
            <ecNumber evidence="3 8">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000126</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="function">
        <text evidence="7">Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Weakly relaxes negative supercoils and displays a distinct preference for binding single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3 8"/>
    <dbReference type="EMBL" id="QCYY01001015">
        <property type="protein sequence ID" value="ROT81135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYD3"/>
    <dbReference type="STRING" id="6689.A0A3R7SYD3"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000001">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.140:FF:000002">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056452">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 3-BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23546">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPO_IA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="10">
        <location>
            <begin position="169"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT81135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="800" mass="90418" checksum="D6A6EA76C4CACEAA" modified="2019-04-10" version="1">MKSVFMVAEKPSLAQSLAEILSNKKCNSRKGFNGACSVHEWTGSFCNQSVRFKMTSVCGHVMSLDFPGKYNNWDRVDPAELFRCPTEKKEATAKLRMPEFLSKEARGCDYLVLWLDCDKEGENICFEVISCVESSMNRSYREQTIFRAKFSAITDRDIKAAMNSLIEPNENESRSVDARQELDLRIGCAFTRFQTKFFQGKYGNLDSTLISFGPCQTPTLGFCVERHDFIQSFKPETYWVLQVKVAVTEERQMNLDWERGRIFDKDVANFFLNLVKEQKRAKVVRVTMAEKTKPRPLALNTVELMRVASSGLGMGPQQAMTLAERLYTQGYISYPRTETTHYPENFDLKGALRIQEGHSDWGSTVREILRDGIQKPKKGHDAGDHPPITPMRCADRNQLDHDSWRLYEYITKHFIGTLMPDCIYLSTTICISIGAENFSVNGKQLLDPGFTKVMDWLALQDEEKLPDVKSGDEFAVLETRLSERQTSPPDYLTEAELISLMEKHGIGTDASIPVHINNICQRNYVQVSSGRRLVPTSLGIVLVHGYQKIDPDLVLPTMRSAVEEQLNLIALGKADFNAVLRHTLEIFQLKFQYFVNNIGGMDELFEVSFSPLSASGRPLSRCGKCRRYIKLVETKPIRLHCVNCDETFAVPQNGIIREFHENRCPLDDYQLLMWSGGAKGKSFTFCPYCYNNPPFPDMAKASGCNLCSHPTCEYSRDNTGVSQCMECPSGILVMDAASGPKWKLACNKCDVIINIFQKASKVQVLSDTCEDCGSQIVTVDYKEGSTKLRDGQLTATELLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SC59</accession>
    <name>A0A423SC59_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020383</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003985">
        <property type="protein sequence ID" value="ROT61808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SC59"/>
    <dbReference type="OrthoDB" id="6378979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000003">
        <property type="entry name" value="Transposon Ty3-G Gag-Pol polyprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="4">
        <location>
            <begin position="169"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="5">
        <location>
            <begin position="387"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="698"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="737" mass="83542" checksum="A007AB384FAF2C5E" modified="2019-05-08" version="1">MEVANTSPINTHGERSRTLSLEGEPAQRFQWIFLVADVPQLIIGADFLAHYGLTVDLQGMALIHQSRARTHAAPAVVSTPLIYTVLPRTCAFKNILREFPALTKPINQATQPRHEVRHHIVTHGPPAHSRCRPLAPDRCRSAKAEFDHMMQLGIIRPSSSQWAVPLHLVKKKDGDWRPCGDYRHLNTITAPDRYPLPHLHSFSHELSGCMVFSRFDLVRAYHQIPIAEEDIPKTAVITPMPFGLRNAAQTFQRFINDVNRGLEGVFAYIDDILVASASEADHARHLRALFGRLQEAGVVINPGKCLFGAASLSFLDHTFTSQGITPAQEKVTAIRKFPKSAPEKQLRKFLGMFNFYRRFVPKCAQLLKSLHALIPPNRASRNTKIKWTPPNNEAFEACKEALAFATLLNHPLPEAPLNIAVDASDTAIGAVLQQQQVRHFLPYLEAKEFHILTGHKPLTFALHSRTRRQSPHEERHLDYISQFTTDIRHIRGADNEAADALSRVTIAAATHADDAVDYHLVSSEQRQDASMIPLIEGQTSLSLERVKIPNSRDDLLCDVSLGYPRPYIPPSLRRRFFEAYHQHQGIQATQHLVHRMPEDQSLQAYKISLPDVPYPRRKVPTHPHRYSETPALGRRLQLHPDDDRPLHQMTRGYAYPRHHRSDGRQDLPQHLDLPFRHAGYRHYRPRRTVRVGTLAPADGITRFQENQDDRLPPLRQRHGRATPPAYEAGRPTPPCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFA9</accession>
    <name>A0A423SFA9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TEP1-F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_019284</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds covalently through a thioester bond to the pathogen surface resulting in pathogen clearance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a TEP1-N chain and an TEP1-C chain non-covalently linked. Forms a complex composed of TEP1-N and TEP1-C heterodimer, LRIM1 and APL1C; the interaction stabilizes TEP1-N and TEP1-C heterodimer, prevents its binding to tissues while circulating in the hemolymph and protects the thioester bond from hydrolysis. Mature TEP1 and to a lesser extent full-length TEP1 interact with SPCLIP1; the interaction is induced by microbial infection.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003534">
        <property type="protein sequence ID" value="ROT62853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFA9"/>
    <dbReference type="STRING" id="6689.A0A423SFA9"/>
    <dbReference type="OrthoDB" id="9998011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1930:FF:000001">
        <property type="entry name" value="CD109 isoform 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041555">
        <property type="entry name" value="MG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF136">
        <property type="entry name" value="CD109 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17791">
        <property type="entry name" value="MG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0882">Thioester bond</keyword>
    <feature type="domain" description="Macroglobulin" evidence="8">
        <location>
            <begin position="105"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Macroglobulin" evidence="9">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="493"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="555"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="590"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="607"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="633"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00057615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00063781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00078071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT62853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="699" mass="77895" checksum="1591D60B36E8E1C8" modified="2019-05-08" version="1">MWERRTYSVVAPRILRPNRDYHVVVSTHGTAKPVKVNVEVGGQQDSGGVILNRQLADLQPDSSQVLNFQIGDLGPGQYNLTVSGYEGLTFSNTTALQYVHKSYSVFIQTDKSIYKPGDLLQFRVIVVNPQLRPSVTGAIDVFITDGKGHRVKQWKRVFTNKGVWSGELLLAEEPVLGRWNITVDVLGQTTSRFFEVAYYVLPKFEVVVDLPEYATFDQKEFTATVNAKQHTLPVPLTAFLPAPRARYITGPGVASPRARGLGGVRPPSNGAAVTWSRLQYTYGRPVKGEVTLQVTPTYKYGYLQAPYDDPIRVVKQIKGKTDITINLEGDARLKGDYARELEVTAYVQEELTGRVQNSTAHVTVYRYPYRMSLVRTSDSFKPGLKYTAYLKVSYQDDTPVTSGEVTVRHTFTRDAEGFIETTHEIPASGVVTLDFQPPLDDDVVSLALEARFQELTQWLGEITRAQSPTDAFLQVTLLTQEPKVLPVHVVETDPLGRRRRRPDAHHHQTGRRGGGRGPERHAAPHLLRVPGAGARRRALRPDAAGPPGDHAQLQVHRHRRHGPARPPRRLLRAGRRRTRGRFPPLHRLRSHPESRVCQRVSEDCGRGRRRGHHRHHEAQRLRGRPGGGPAVSHPRERKPSDAGRRDTRAGGLRPGPREPGGVALPAPAEAGAVQLARHHHRQRRLPGASLARVASRPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFD5</accession>
    <name>A0A423SFD5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TWiK family of potassium channels protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_019251</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003530">
        <property type="protein sequence ID" value="ROT62883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFD5"/>
    <dbReference type="STRING" id="6689.A0A423SFD5"/>
    <dbReference type="OrthoDB" id="297496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF334">
        <property type="entry name" value="FI03418P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="43"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="180"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="349"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="349"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT62883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="47914" checksum="CC6BDD08BEBF5B1E" modified="2019-05-08" version="1">MNYMANLFWFYVDKNWTLDSFNATVYKDLKKLESFIISAVQNYNYDGTVMNWDYSWTFPNSLLLTMTIMSTIGYGHISPVTSWGQLFCIIYAIIGCPLLLVFLGNLGNSMAESFTYIYSRCCCRWCRSVRNLSELPPRASKKQRKLLIDDEVGKEEYMPTEHVRYFLFFLDVPITLTLVVLYVYIMLGAVLFSVWENWDLGSSSYFTFVTLSTIGYGDMVPGTALLSNEDPGTAGLKMAVCIAYILLGQCASGWLKAVPSPLLTSPPVPPPVPLDLLLPFCRPPPCSPPPPSLPLLTSPPPPSPLTSSPSSPGMALLSMCLNLMQEQIVEKCRWLAREIGLTGKNTVEEAKGTDKKALDLPAGDKKKPKDSKDVEKAPPKDVEKAPPKDVEKAPPKDVEKAPSMDTLSVPSSAGSRTSLLKSPTHSIPGALEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGS9</accession>
    <name>A0A423SGS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018794</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003449">
        <property type="protein sequence ID" value="ROT63343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGS9"/>
    <dbReference type="OrthoDB" id="6357120at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="913" mass="100417" checksum="5BD85A26FF341E30" modified="2019-05-08" version="1">MEMMCPAGQMPKFTGSDMTQKISADMEMTCPAGQMPKITGSDMTQKISADMEMMSPASQIPKSTYSDMTQKTDTDMEITCPAEQILKIPGSNEMTQKLLSDMEMTCPAGQIPKLNRNETFQMASLGSELTGPAVNKKRRKSILRTATSSHEAEASMPKEERTVMFNLDPQFHCSLISNAEENNDRQMSEGKQVLGDSQGDAQQGSLVGESQKVEKRLVLQSFLEVPVREGDSHEKQGEEQQTNALRTMKNVECNEGNENAGNFTKGSGKRLQGVSPDESSLKVFLSEEGPKCSLSVISAVGQVDEDNKTQNITSDMNVTCSEGASKINHVEVTACPAGQTSEVTGDVTKEEQFDQGLNKEHNKEMQSISNGESVTLDESLDGINLVMENSGDNAETWLHSEPALKEKPLESSYCVSEMKQQSQSRRKSLAADAMDSVLPLMSSFMERISMMNHEQSQLEETILKEMTLVEEQGKEVTLSAEHTKVMLHSVEGELEDMRTTSVCNEVHDPVEMQNSHINNSIQGYQTTLDDSEGTGTVKLHLTSLEPTATAMTVKDIPQTLGMADTSVKETKNILVEEDCLKTTRSTESHENSLTERMNENSMQLDSDPGNAEEKKRVHDTYMAEEKESEMVTEETTEVSSYPSSCDVRPTTVKRSAPSETMAQSILTVSLENSALQINSSLIQQCNMSVSQNLTHDNTSLQCERCCSTEGCIVFQSKNAVWTVSKVYNGGRCLSLKHTPLELDLQLSQCDNHWTIVTALWKPQTSEIQNKCGRLVMSVLGCRVGAAVTRLSGLVFCEAKEALAHVVTAFNNVVDLILEMKILAALHLTSFESDSVKVTLFNLNAHVSVDVTVRVHPPEEAPEHPYTLQPAAKVTIGNLRCQTLDEAMSEVSSGPRQLLRLIQAANSIVRNMSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHB2</accession>
    <name>A0A423SHB2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018562</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01003425">
        <property type="protein sequence ID" value="ROT63549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHB2"/>
    <dbReference type="STRING" id="6689.A0A423SHB2"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000051">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="10">
        <location>
            <begin position="157"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT63549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="365" mass="40636" checksum="BF135CEDCCF69979" modified="2019-05-08" version="1">MGFGAEDQYTTRTPPLRSSPLSLSLSHPAFTKVGFVGARGKGTGGPSSAPHVILRHPPITQSPGAAAMPSVGPELVHATSISFLRDLATSVVCVLPFAGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDTMGWGENDRGVSFTFGAEVVAKFLHKHDFDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKKFPYGGLNTGRPVTPPRGAANQKNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHS4</accession>
    <name>A0A423SHS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">A disintegrin and metalloproteinase with thrombospondin motifs 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_018383</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003392">
        <property type="protein sequence ID" value="ROT63715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHS4"/>
    <dbReference type="STRING" id="6689.A0A423SHS4"/>
    <dbReference type="OrthoDB" id="10035764at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04273">
        <property type="entry name" value="ZnMc_ADAMTS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF275">
        <property type="entry name" value="STALL, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0401">Integrin</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="3">
        <location>
            <begin position="271"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="696"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="936"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="939"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="437"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT63715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1141" mass="128921" checksum="B394DC8084FCD9C2" modified="2019-05-08" version="1">MTLITYYLISKRVFFQVLGEEDVLSEEELQLVFGRRETVPKYNLVVPRVSGDGWHPRRSARSAPEAPTLKFDALGRSFNFKLQRNTELISPEFVFMQRNGDEADIMDLDERNYEMYYQGVDDTGDSNIAVELSNNIRGVITSASDQYVIQALPETVTRRRRSIEPERERDDDALPTHIVYRRESHDEECPSESHSRRRRSFISDTEEISRMEAQQEESRAALGAREGRRSYYDSFEHVVDEQLRSEWHRDNRYGPEGHEDTRARGFRGEDLYIETAVFVDKDLYRHMQDNFPRDTEDQVLKVVLAMVNAVQLLYNDDTLGHRIKFVLKRLEILYKDPTDLHRPYDIDNLLTNFCSWQRKENPPRDSDPLHWDHALILTGLDVFTINSKGRVNSQVVGLAPVAGMCTPSSSCTANEGRHFESVYVVAHEIGHNLGMRHDGLQAGNNCDPGRYLMSPTLGSGKITWSSCSKRYLDDFLSTPQAECLRDSARPLRDPLNHEQYSPPGQRFSADQQCMLKHGVGSIHAASQPLADICQDLHCLSTEIPTPGHRILLSKEPPAATESVDGVLSSGSTGLSLSERRCRTCHGEYRYRVCSAVQKCSAGRRRTVQDFADDTCRDTARNSAFLTGLAARVPARGPSQCEVQCETSGKGERSSGRSFPDGTVCASPSRLPSYCVAGVCTVEFRCEADALYGADPLTCRPDMAPPTPPPPRTSHANTRRTPRPLDTPRPSLLQDTARLACGARGFLRLRVVLAKGIQLVSRDCRSHRCTGINRNIQICNPSNSGCERIQSTFEYASEVCRRYMTEVDQLSGIGMQLSSTKDDPDRACTVACQDARLNYRFYRVNGGDGWFPFGTDCARGTAGRSAYCLNGKCLDFSNEGTPLRNTIFTEYERQRSLDMEPIERAYPLEVNPYHEDFRQPFYQESSPQQTYQWQTQHVQQPHRPRQSTWFRGRRKRDVTSSSHPISSTISDQLLMSLVDELNSTLMSKETSSKVTPDSIDFQNPLFVGEQVTENNTFTLNPNSFELKPFNPSNLTSEGGVDEEVQFDALQEYRWRLRVSPCSVSCGKGVEEVLLLCVQRDREDLPVADRRCAHLSPPASVGFRPCWREEPCPRRPPDEGLSASPVGRWVLGLLEGIVDTRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHS9</accession>
    <name>A0A423SHS9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GT23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_018389</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003394">
        <property type="protein sequence ID" value="ROT63709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHS9"/>
    <dbReference type="STRING" id="6689.A0A423SHS9"/>
    <dbReference type="OrthoDB" id="2014825at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046921">
        <property type="term" value="F:alpha-(1-&gt;6)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045573">
        <property type="entry name" value="Fut8_N_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027350">
        <property type="entry name" value="GT23_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19745">
        <property type="entry name" value="FUT8_N_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51659">
        <property type="entry name" value="GT23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GT23" evidence="8">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="168"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for donor substrate binding" evidence="5">
        <location>
            <begin position="30"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT63709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="39401" checksum="162F0130F322D86D" modified="2019-05-08" version="1">MRMTEGFQEYVEKLGARLGFESPIVGIQVRRTDKLRLESRFIGIEEYMEIVHDFFNDLEVRGTNVTTRRIYLATDDLNVIQEAKKKFPNYKFVFNEDSVASASLGRRGSVDNMKYLMADILFLSRSDFLVCGMSSNICRLAYELMQTLHSDATRKLVSLDLPFCIHSQSAHEVEARFPHTPRSGREIALQKGDRVVRSVYYYSKHRNSLDGFWHGTNRRTRKTGFYPIYKTVEVQSLADTPSFDWIDRSEDYLVTKSSRWWRRRRPSMSHRWWRRRRPSMSHRWWRHCRPSTSHRWWKRRRPSTSHRWWKRRRPWSRPRATDGGGAGDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI97</accession>
    <name>A0A423SI97_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003362">
        <property type="protein sequence ID" value="ROT63873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI97"/>
    <dbReference type="OrthoDB" id="6369184at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052129">
        <property type="entry name" value="Spermadhesin-Link_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46908">
        <property type="entry name" value="CUBILIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46908:SF4">
        <property type="entry name" value="TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019040392" description="CUB domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="30"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="268" mass="30070" checksum="A45A7312B3D543D8" modified="2019-05-08" version="1">MIVSALFLGVVAAVGGANAFSERALETLPCGTTTMNPGERVAIQSPNFPQNYDTSYRCQYEITCNPMESTYLEFICPTFELESSTDCLNDRLVVTYHGSREEKCGTDSPDGTITSDGWTRLTFASNAATTAPGFRCYIWCREQTTTTSTTTSTTTTSTTTTPTTTTTPTTTTTPTTTTTHNYHTYHHHLHDTYHDHHTTHHTYHNHHTHHNHTYHNHTPDNHTSHNYTHHSSLLDSEACTNYSHASAGFSHRPDKRQETFNTNVHKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJK3</accession>
    <name>A0A423SJK3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative serine proteinase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_017693</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003260">
        <property type="protein sequence ID" value="ROT64349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJK3"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF278">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR 88EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018982441" evidence="5">
        <location>
            <begin position="19"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="6">
        <location>
            <begin position="43"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT64349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="44295" checksum="E7C9AA46F1B86069" modified="2019-05-08" version="1">MRVCVLLPALALLSRASCQCLSSSDTSPPPRLQILKKTTPFSLDLLKKALPPTGNFFISPFSVWSALVLAYFGSRGNTKAELEQVLRLTNREDTLALFRALERRYDSQEANQNYTINSANRIYFDQSIPVRECVGKVLDDKVKLIDFNRPDAAAADINAFINAETRGKIPKLIEPSFVKDAKMVLTNAVYFKGFWKYPFNPQRTHKDNFFINPKAALQVDMMSQTGISNMVIGLGEASRPGAGDALQGRRRVHGGAPPAKWESQGGGQAGPTPEAQETRVSVLKAMPSVPVRVKFPKIIVESALEDELISTLKNMGIRDLFSSAADLTDFTHVRGLMVNGAIHKALIEVDEEGAEAAAATVLVMTKSSMTPKTTFTCNRPFVFYIKDNEANNILFMGVYRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMI2</accession>
    <name>A0A423SMI2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear fragile X mental retardation-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003083">
        <property type="protein sequence ID" value="ROT65458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMI2"/>
    <dbReference type="STRING" id="6689.A0A423SMI2"/>
    <dbReference type="OrthoDB" id="6382250at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="12399" checksum="A4F95989D83C2D75" modified="2019-05-08" version="1">MKNEIMKKHKLHQKAKKTKSKEDWDGFKEQRNKVTTMLREAKLEYIGAHPEEDVDKILAEAAMQGNIKDEENKGEASATSEANVDSPAVPEGEGAKPRPWTRQRRTGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMR2</accession>
    <name>A0A423SMR2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tetraspanin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016592</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003084">
        <property type="protein sequence ID" value="ROT65451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMR2"/>
    <dbReference type="OrthoDB" id="6363129at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF544">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="40393" checksum="4A6756FF1B39C6D9" modified="2019-05-08" version="1">MVLFPSSSFLPFPHLLLPPSSTHVQVSLHLPKHSAWAGQGNYSGNEAALGRRPSIRWNKILFHEAKQDRKRSSSGRVAPPALACSERETDMTDSFTSIGMCSQMTGVAVMVVGVWCVTGDGRDVMLALAPTPADTPTLIHLAYGLVGAGGLVLLTSILGVWAALKENKCGLGMYVTIVVLVITGEVAVGVLGVMYQLRAVSSLGESLTTRLKALYGSPGHETFTLAVDYVQYQVRELASRRRRAQEFVGVCLGSFMLQSLCLCSHRALLHKGKVIAAIASRTVTHRPRRLLAHSGHLLVRNRNLLSALALGEASRKDDGRTVAGISTLCLSRFQLAALKSQPLAARWSENYLPLIHLDAWRRSRNENGKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNN2</accession>
    <name>A0A423SNN2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003040">
        <property type="protein sequence ID" value="ROT65769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNN2"/>
    <dbReference type="STRING" id="6689.A0A423SNN2"/>
    <dbReference type="OrthoDB" id="6350022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="4">
        <location>
            <begin position="57"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="789"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="814" mass="90443" checksum="98AA7361176BECA4" modified="2019-05-08" version="1">MNLTPVPLEIRGGVPVLNFEFTDLPIREFDLPTPSPVSGSHSPPQRKALENEVQGMLDMNLIKRSNSPWASPMILVPKKDGSFRPVVDYRKLNAVTIPEPFPIPNLRLLLQDIGSGNLVFSTLDLAKGFLQVPVAKESRPLTAFSTHMGHFEFLRTPFGLRNSPLTFSRLMSIVLSEDVPFVWAKETEDSFLQLKALLANAPVLAFPDFELPFVLTTDASSVGLGATLHQKVNGKLRPIAFASRTLKPAERSDPHGRRARAIEVLAEYDVTIVYLPGRQNVVADALSRAPLPSPAELQACKSTPFPPSFAKRHEARTTAPVLANVANQPVDPPSEEEIRRAQREDPVYMDIIGKLERGEPLVPVRRLPVRQFYLADSGLLFRRATPKKIKGRRGLVRDVVVIPESLEPRVLQLVHESREAAHCGVYKAIQMARQRFFFPLLITKVKKHVKSCKVCPYFKGSTNQPAPALRYDVPDFPFEKVSCDTLSGFVTTRSGNKHILVFVDNFTRSLVDTSDNWDDLLLTIQSAINSTFHSSLGDTPHFLLYGSDKRLPYDLFQTRRKPEYSDSVGALVFRKVHTSDSMRPKLAPRFDGPYRVLEMLVLMLLAMASPLLAEPGLPERISTSSLNKLPPISSIPYSPSQIAFLSILPLNPSSRFQYRTNISSISSLPFDDISVLYFFQPSTATVTCKEALPDVVVTGIYVLPISCEIVTTSLFIPASHSYATDISVRGLNISPMPFHLSFPYSYSLVLSLYIPISHPTPPLAPLFLHARARHGCARFRSTYHHSDTCQKSRASQPVNPDAPTPGRHLATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRT7</accession>
    <name>A0A423SRT7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002875">
        <property type="protein sequence ID" value="ROT66935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRT7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50184">
        <property type="entry name" value="VWFC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFC" evidence="2">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="516" mass="55058" checksum="E5515C70117EC517" modified="2019-05-08" version="1">MDTHLARCSAGCEHDGRLYAVGETRYLGKCEEQCRCGADGKFSCGPVACAPGLFPAGQHSQEELCIELRNRPDTDECCVVVACVNSLTRPSLLTSPASSPLAPAAEEEQPLGQAVRALSGRTAGGEDLAEPITEEEYQRRLKDLEHELNKNSKKKTPFTKPTEKPAVEDLASSSSDDSSNATAVEGVESMVDVTEEVPQDDESLAEVTTTIPETPDEKGEPAVIVEIDHHGEEIHRITVQEAVDVVTLAAAEEEATTMAPTEDEGPAPEESVGDETVSSVMAAKEEEAVTSAVLAEGEDAPTPAVPVEEGTTTETSVMEEMPADKKEEAAHDMKEESTPADKEEATPADEKEEGTPAEEEEASASPAATAEEQEGLTTEAAEEVATTTPAPAEGEEVPVSFREAKKAPEDANVTETVAEEAVGLKEKPCINPPLPLYCYACQPLSYHLLLPAKPLPYTPTLLSTSTQLTLIPLDITKPKHLFPNLYGLTLRPASIPYLTPTLVRSKLTLTATYSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STD2</accession>
    <name>A0A423STD2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_014471</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002808">
        <property type="protein sequence ID" value="ROT67474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STD2"/>
    <dbReference type="STRING" id="6689.A0A423STD2"/>
    <dbReference type="OrthoDB" id="103349at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004065">
        <property type="term" value="F:arylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.550">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050738">
        <property type="entry name" value="Sulfatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693">
        <property type="entry name" value="ARYLSULFATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42693:SF49">
        <property type="entry name" value="SULFATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14707">
        <property type="entry name" value="Sulfatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="8">
        <location>
            <begin position="54"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT67474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="621" mass="69407" checksum="736558D600503BA4" modified="2019-05-08" version="1">MRDACPRPVTRPSELGREERTRGSQLAVMARWRAWFLAAAAAAAATVSAARRPPNILVILADDLGIGDLGCYGNDTIRTPHIDKLASQGVKLTHHLAAAALCTPSRAALLTGRYPFRYGLVGDDANRAAPVLLHVASRAHLPLDEVTLAKALSAANYSTALVGKWHLGVQCGFLGRSCPGPLNHGFDTFFGIPVTLFFEFRGPYAFWKFDFSQPSYQRLLGTWVVAMASIALGKKYLGWRTRTVILLLLLSNVFFFLYWFRVAHIGFNKECLWGVSPWMHRMANSMILRQDKVVEQPIQLDGLSQRFVKESREFLAQRAEDERPFFLFHSFAHVHTPMFSAPHMTGVSKHGSYGDNVEEMDESVGALMDALREFGLEDNTIVYFTSDQGGHVEAMDFEGRRIGGHNGHFKGGKAMGGAEGGIRVAGIYRYPGHLPAGTTLDTPTSLMDLMPTVLDLAGLPSVHDLVPRTPRKDLDGESIADLLKGKSLPARPPRIFLHHCRKHIHAARLVTDDHVYKMYLYKHKWFPGTTQCGWGHTVGCSCAKAMMHDLTEQPELYDLVRDPYEDHDPISPETDEYKKVVGALMQHLDQWNRSVHYPTPQLASRLDIAWLPWRQPVCFNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STY0</accession>
    <name>A0A423STY0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Solute carrier family 23 member 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_014272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002785">
        <property type="protein sequence ID" value="ROT67650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STY0"/>
    <dbReference type="STRING" id="6689.A0A423STY0"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11119">
        <property type="entry name" value="XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="595"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="726" mass="77670" checksum="D01B9C4D29BD186F" modified="2019-05-08" version="1">MSTPTAAPPDDPLLARKSSSTPSVAPAGLAKEPGCKKGSSDLLYAIEDNPSWCECIIFGFQHYLAMVGGTISIPIIISSYLCLEESNPARGVLVSTIIFMSGVITFLQATFGVRLPIIQGGNFSFLIPTIALLTTAHAPCDALPLANMTQAEREEAWQVRMREVQGSIAMSALFQVAVGFTGLIGLLLTWITPLAIVSTVSLVGLSLFDVASKQGSGHWGIYLLTLGLLILMSQHMRDVRVPVPFYERGKGFVMVKCQPFRTTSFLIAIFITWAVCGILTMSGTLPEGSAARTDLTMPMVARAPWFYVPYPGQFGMPTTSVAGTLGMLAGVLASIIESVGDYYACARISGAPMPPTHAINRGIGTEGIGCMIAGLWGTGNGTTSYSGNIGILGITKVGGGRPLCQALLPYAGPLCVGEEMVSLSTSLSLYGLSPSSSLCFSFVLPLSLPLPLLTLFFFPHTTPLFLFPYTTSLFLSSPSPFLSSSLHRPSLSPLFSSLRRPSPSLSSPLHRPSSPLSSSLHRLSPSSSSTQVASRRVVQVSAIIMIVCGMFGKMGAFFVTIPEPIIAAVFTIKFAMITAMGLSTLQFVDLSSSRNLFIPGFSIFFGSLWMQDHGDAISTGAPLFDQTVMVLLQTSMFVGGFLGFLLDNTIPGTDEERGLVAWKEKLQTSAEGGDDVINTCYDLPFGMGLIKRAKWMRYIPFCPRYKGISKDILPSCRKSNKNAAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVA3</accession>
    <name>A0A423SVA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002717">
        <property type="protein sequence ID" value="ROT68124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVA3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="46773" checksum="B3CDD70E433CEDA0" modified="2019-05-08" version="1">MSLVSVCPFFVSLSLCRRILCLSLSPFLCLLSLFRFFALSVPFVCPLFFHFLVSLSFSFFVSLSLSRLLLSSLFVSLLCSRFSFSHFLLSLSLISLSLSASLCLSFPLSLLSPFPLSLSSSPSRVFSILLPSFSHVLSFFLFIFHSLLSQYVVYAVCSPCLSEYLSGLSVLFFLPSSLSYSSLSLLPPFLLFSKNSSLPSFAFLLFLPFFSLSLIPSPRRVSSAFLCLASSFSYSLPIPSLSSASLLPPSLSLSSRPLPTTLSLSSLSLSPISLLTLPSSSLLSLPLPPLHSLISLPCPLPSSLFFSPAFLVCFCLSLFSLSLPSSLFLSSLPPLHFSLIPALPSLSLLLSSRLSSPPLPTLPLSLSLPFSLSPLSPLSFLPSIYLPPSFPPLSLSLSPHGQFLKTAFFVRQSWLEEWQLCKPVSPFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXN9</accession>
    <name>A0A423SXN9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Trypsinogen 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_012955</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002624">
        <property type="protein sequence ID" value="ROT68893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXN9"/>
    <dbReference type="SMR" id="A0A423SXN9"/>
    <dbReference type="OrthoDB" id="10059102at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000077">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018970738" evidence="8">
        <location>
            <begin position="16"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="30"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT68893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="266" mass="28259" checksum="1C9C1EABF7C2DF3D" modified="2019-05-08" version="1">MKTLILCVLLAGAFAAPSRKPTFRRGLNKIVGGTDAKPGELPYQLSFQDISFGFAWHFCGASIYNENWAICAGHCVQGEDMNNPDYLQVVAGELNQDVDEGTEQTVILSKIIQHEDYNGFTISNDISLLKLSQPLSFNDNVRAIDIPAQGHAASGDCIVSGWGTTSEGGSTPSVLQKVTVPIVSDDECRDAYGQSDIEDSMICAGVPEGGKDSCQGDSGGPLACSDTGSTYLAGIVSWGYGCARPGYPGVYAEVSYHVDWIKANAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXR5</accession>
    <name>A0A423SXR5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002611">
        <property type="protein sequence ID" value="ROT69044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="729"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1595"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1997"/>
            <end position="2378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="729"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1292"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1303"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1603"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1624"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2005"/>
            <end position="2016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2026"/>
            <end position="2369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2391" mass="240339" checksum="CE105FE4A81CECB6" modified="2019-05-08" version="1">MESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSKPPLQLLHLAPAPHFSNYHHSGLYSLKLTNLFNLHQLLFGATTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTLLLIQFLFRTHHFFYLSKLLIRFNHLLLEATTSTASSSSSTSEETTMSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSRLYSLKLTNLFNLHQLLFGAHHFYFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTLLLIQAPHPIQPPPPPKPPLQLLHLAPAPDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTESSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDLLWIRLQLAPAPLRKQPPLQATPAPPLPQIPPPLWNQVPLQRYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDLLWIRLQLAPAPLRKQPPLQATPAPPLPQIPPPLWNQVPLQRYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTESSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSIQPRLPSNPPLLQLIFCGFDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYY4</accession>
    <name>A0A423SYY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative sialin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_012426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002568">
        <property type="protein sequence ID" value="ROT69372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SYY4"/>
    <dbReference type="STRING" id="6689.A0A423SYY4"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="160"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT69372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="201" mass="21704" checksum="4F5B756FE978DA61" modified="2019-05-08" version="1">MSNTSAILVTRLRNTIFHPRDSGYKSRVDDPDGAEGEKTHGIYHISGEDTGENVHKEADADGGGCWGVRYTLCLLLFLGITQIYMTRVCLSIAITGEFDWDATTQGLILGSFFYGYVAPTSWRAGGRGPGWAPRVRAGRGPVVPPDGGVAAVRLRVQGTLHRQQGPAGPRAGRHLPYDSHDDGDLDSPPRPSSGRNHRLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZJ0</accession>
    <name>A0A423SZJ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Heme transporter hrg-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_012141</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002540">
        <property type="protein sequence ID" value="ROT69637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZJ0"/>
    <dbReference type="STRING" id="6689.A0A423SZJ0"/>
    <dbReference type="OrthoDB" id="5954402at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026218">
        <property type="entry name" value="HRG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31525">
        <property type="entry name" value="HEME TRANSPORTER HRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31525:SF1">
        <property type="entry name" value="HEME TRANSPORTER HRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16954">
        <property type="entry name" value="HRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02095">
        <property type="entry name" value="TRNSPORTRHRG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT69637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="153" mass="17296" checksum="F5CCC1CE9C4D107A" modified="2019-05-08" version="1">MARRGGCCMYFNLVMAVIGTFGGWSAFVVFFFHFTNHQAGIWAFVSGTYAAMTLFIHILYKRHTLETWYTPENLIQIRLLGLLGLLAGLGAFGAYVGIAISNHEDMPSMTNIATSHYFMAIWAFLSLKWGASLMGFSHVYRKRLLEEYHPLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5N2</accession>
    <name>A0A423T5N2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002246">
        <property type="protein sequence ID" value="ROT71797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5N2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="42706" checksum="5256BF09168F4A71" modified="2019-05-08" version="1">MSWSVWFRCSFLISFLSFASLADFRSFLLFLSHPLPRSAPRHSPLHPTSHATQSHLFVRLTSMLMRRWPYFSLRLAFLCFSATFRHSFLSFGTIYIPFPLTNLSLSPFPLFPHFSPLQLICTWRPIQVSPSLASFLFFPSLLLARCFSISSLFLSSTSTLPRSLPFFPPLLFLLLLNFSSSLFSLLFSLLLLLPSLSFSSSSYFSPPPPSLSPSLLPSSPFTFFPFSPFSPISPKMIFRSSFLIQFPFALYYVLPYYSSSSASSFPSSSPASSFFFSSYSLLSLQPSFSYLSPPPLSILLISSSSHTPFPLSASTPLSFLLFTLVVLDSLVRFLAHSPRSLSVPSLLLRTFSSILTFLLPNSSGALGMLDSSGFLTLLCHLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8C6</accession>
    <name>A0A423T8C6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002121">
        <property type="protein sequence ID" value="ROT72694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8C6"/>
    <dbReference type="STRING" id="6689.A0A423T8C6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="58536" checksum="B3590B09E26FBF0C" modified="2019-05-08" version="1">MTLSYRTSTHRSPFPQQDSLQQDSPTWSTNTGVSRPTVSHTIRFPLHIWDSLPSPILTLSSPNRDSLHSPIQDLSSPIQDSLLPHKTLSLPHTGLPPHTGLSPSPIQDSLPPPYRLSPSPIQDSLPPPYRTLSLSSYRTLSLPHIQDSLPPPIYRTLSLPIQGLSPPPYRTLSLPIQDSLPSPIQDSLPPPYRTLSSPYRTLSLPIQDSLPPPYRLSPSPIQDSLPPIQDSLPPPYRTLSLPHTDSLPPPYRTLSLPIQDSLLPHTGLSLPHTGTLSLPHTGLSPSPIQDSLPSPHTGLSPSPIQDSLPPQTGLSPFPHTGLSPPPSGLSHTGLSPSPYRTLSLPHLSHTGLSPPPYRTLSSPIQDSLIQDSLLPHTGLSPSPIQDSLPPPYRTLSLPQTGLSPSPIQDSLPPQQDSLPPQTLSLPQTGLSPSPIQDSHTGLSPSPRTLSLPHQDSLLPQTGLSPSPIQDSLRTLSPPPIQDSLPPPYRTLSLPYRTLSLPHTGLSPSPRTLSLPHTGLPPPPPYRTLSLFLRNFPPEAVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9R0</accession>
    <name>A0A423T9R0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_008448</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9R0"/>
    <dbReference type="OrthoDB" id="6376466at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000075">
        <property type="entry name" value="Putative zinc finger protein 536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="27"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT73132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="140" mass="15293" checksum="C85D2FF0D0BEB3E9" modified="2019-05-08" version="1">MPHLTKEVKGHSGLVCGQLLQILENTGGSSKEPLKPSAADDTSQVLLGDGSGMSGVPQMPSVPGQLDDSGMSPHSSRPPMRFFCPVCPKGFRSKLDVERHLRTHTGEKPFQCPYCPHRSATKGNLKAHMRHIHMDVRLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGG9</accession>
    <name>A0A423TGG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001758">
        <property type="protein sequence ID" value="ROT75558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGG9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="19484" checksum="2241BEF74B6E2ACD" modified="2019-05-08" version="1">MLTFPSDSEYGHLQEISGAQVRPTTMSPSRPSALLLLLAAVGVGVGVGAESANSLSVIEASRLLALDAEIVRGLRAYLEEEEERRQREEAEGDPESHTPEHPWIPAPLASIRRYIHEFDAVTEGHVGANFEPGGNEGVPSADPLRTLVIARRLGRDWPALRDAHFRNNMSWQAMVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGX3</accession>
    <name>A0A423TGX3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005754</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001745">
        <property type="protein sequence ID" value="ROT75698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGX3"/>
    <dbReference type="STRING" id="6689.A0A423TGX3"/>
    <dbReference type="OrthoDB" id="6365100at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="75"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="175"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="235"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="316"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="352" mass="38914" checksum="449B63E7E7584672" modified="2019-05-08" version="1">MGSGLSAETRNLISLSQAGDVEGLQEALESLPEDSLKPLLGKVTVLSYCMSMSGYEAIVRLLLEKGAKVNAKNKDGDRPLHSAVRGGSEAVVKTLLRKDGIKIDAADGAGRTPLHLAAEKGHNRIIQMLLKNGANVNAMRNDGWSALHEAAYNGHWTTLQQLRDQGGKVGGLSKTNDTPLHLAASQSHPLAVFTLLASGASTCQRNTDGKTPLNVERTNTFPGQYDKILSQCVSLTEATQNWQAAEEEKLKLQREKEHLQKEQEQKDLEAIKRNTEVINLQNETLALRRDLGEKEKHIRSQQDEHHRKVQEITGNYERMKTEAAESQAMNKNLEEMLMTKDEEIRSLQVRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIC0</accession>
    <name>A0A423TIC0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heat shock protein 83</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_005288</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001690">
        <property type="protein sequence ID" value="ROT76137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIC0"/>
    <dbReference type="SMR" id="A0A423TIC0"/>
    <dbReference type="STRING" id="6689.A0A423TIC0"/>
    <dbReference type="OrthoDB" id="5426351at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000001">
        <property type="entry name" value="Heat shock protein HSP 90-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="12">
        <location>
            <begin position="83"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="272"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="742"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="176"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT76137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="772" mass="88172" checksum="D99C7BE7B8016017" modified="2019-05-08" version="1">MAATSPGRFPSNGAHVMPNCLVLAPSPDSRWLLSQQRLFLCQSTLKTHSKMVEETMSEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKIESGKDLFIKLVPNKDDRTLTIIDSGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVVSKNNDDEQYIWESSAGGSFTVRHDTGEPIGRGTKITLHLKEDQTEYLEERRVKEIVKKHSQFIGYPIKLLVEKERDKIVPDEDEDEEGKEKKEEEEDKDKPKVEDVGADETADSLLAKAKRTKTIKEKYTEDEELNKTKPLWTRNADDISVEEYGEFYRSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKQKNKIKLYVRRVFIMDNCEELIPDYLNFMTGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKALELFEELMEDKDSFKKFYDNFSKNIKLGIHEDSTNRKKLAELLRFYTSASGDEMSSLKDYVSRMKEDQKQIYYITGESRDAVSNSAFVERVKNGGFEVIYMTDPIDEYCIQQLKEYDGKQLTSVSKEGLELPLDEEEKKKVEEKKKMLENLCKVMKDILDKRVEKVVVSNRLVTSPCCIVTSQYGWTANMERIMKAQALRDTSTMGYMAAKKHLEINPDHTIIETLRQKADADKNDKSVKDLVMLLFETSLLASGFSLEDPGVHASRIYRMIGLGLGIDEDDVPPLVEESNPLDDLPPLEGDDEDATRMEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TK90</accession>
    <name>A0A423TK90_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001601">
        <property type="protein sequence ID" value="ROT76855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TK90"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="579" mass="61836" checksum="76C0159E6785E5F9" modified="2019-05-08" version="1">MTSVPSDHLQSFLLHERVSSVPPPCPLVAGGYTFLPGCVQHLPGVRADMTRRSLHFRLAQSSRDSLQSHPSSSAAPLAVLTVLRSTNQFGMFVAWSHPYEPRADSASRIEPPSVKSGRIGGCLSPLSLPPAHSLLSRPLLLPSLPSEPHSLETGEHLLFLHLSPLSLSPSSLSNLSPPPLLSLSLPLSLLLSLPLLLYSLIVSLFSPKVPSHSADIFSLSSSSTFLSSVHFLPSSHLSSSLHILFAVGSPTLPSLSTLSLALRLFLFLLPSSSLLSLSSPPSSPLPPTSHSLTHLHPLFTSVSSSPLFSLSVRLLLAPHTSSILRPSSRPSPLSSLARRSTTVISHLTCPHFFLLPSILFFVSPLLSLASPHPSKCRFEFSASVSLLSRGAGVRWPRVASGGGAMHAQVSGGLPRAPGGPAQRASGCIESSRKSGCDNEVPRLQPQERREAPRVARLNALGCNVAKRWRCATAGQSAGIIADRACRAAHTDKEAVVALISSLGNVCAKGPRRCGARAWLSADTASAGLLLPPPVPPSLYFFLFFRSGYSFCFFSLASIAYSYSSRFFFSNSRLSFLIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRV0</accession>
    <name>A0A423TRV0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized aarF domain-containing protein kinase 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002101</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001279">
        <property type="protein sequence ID" value="ROT79188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRV0"/>
    <dbReference type="STRING" id="6689.A0A423TRV0"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF1">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="194"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="146"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="54635" checksum="005B8695464C7EC4" modified="2019-05-08" version="1" fragment="single">PILIKLGQWASTRRDLFPDSCCRQFAKLQRSVKPHSWKYTKYMMKKSFGPDWRKIFVKFDNNRNPVGSGCVAQVYKVWMSAEAITDEEILTEILSEMEDDVSDSFEGMHVIGFRSLLGLDDGEEVKQKRIIEEWREKRDQMRREAEEKERRRAGIEKEEQNEWQEGVHDKSLPLEEAPPEDLDGLSLWQLRFCTLCVQEFAEVMSYQIDLKLEAENLELFAENFADNPYVRFPRILRPYVTRKVLVETFEEGEQMIDFIGTTGEDKPAELKKRLAEIGVDALLKMVFVDNLVHGDLHPGNILVQNNSAKEEGSNAASGDVVKFMMVDVGCDTFVMHVEPDPNPLRICLLDCGVASRLKEKDLANFKAVFRQVVFGDGESVADLFLNNSEHCCKDPEAFKAEMTSLVNSAREDTIALSQIDVGVLLQQVLGILLRHQVRLESAFSAVVLAVFVLEGLGRTLDPNMDILERARPILVTGKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVP4</accession>
    <name>A0A423TVP4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001116">
        <property type="protein sequence ID" value="ROT80472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVP4"/>
    <dbReference type="STRING" id="6689.A0A423TVP4"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000007">
        <property type="entry name" value="RNA polymerase II subunit A C-terminal domain phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="290"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="474"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="474"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="557"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT80472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="582" mass="65961" checksum="B5D52B2C1FE0E611" modified="2019-05-08" version="1">MLYTKETFRELDAIKKTGFEYKVTQIFLKIGTSIYPRRRLCEVVPYHFFRHTGDINAPQGLQKKENDDQKGYDFENLRLSGDNTEASDGEEGDKKNYSSDSDSDKESKEIVSDSNKESVVNTDKTSDKLDTVSTENVEGSKSNEVNSKTTDVQDTSIVTNKEKDEGSTEVQSNSVESMNVDTETRENGTKEVTDDKENADLTDNKESEESKNSKETDITEEANVKIQDADDGEAGKQKDFIDVADNDDFLLYLEDILKKIHRAFFKEYDKLPQGSTEKDLPDLKRIIPSIRQEVLKGVNIVYSGVVPQQMKLRDSKAYFIATSFGAVVSERLIVRAKGDSEKEDASKKMNYTTHMVAANVHTEKVHRARKHKSIKIVTPNWLWTCAERWEHVEERLFPLSSETEKDIQRLPPHHCYCPDTLMLRSQYDTEDAIPGPSSRTRTPSGSMLEDVNPLMFFSPDEKNNMANEVEQILSDESDDDDGPGNEDNEQESDDEDDEDDEDDSEDDEITPSNKKFKRIEDQDSNSQFSNLRSEDEKEEDSPLPSEVFRQGGGLPSDDSDEGMMDDEGDLSRMGADLESLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY25</accession>
    <name>A0A423TY25_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000988">
        <property type="protein sequence ID" value="ROT81367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY25"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019413278" evidence="1">
        <location>
            <begin position="21"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="42938" checksum="373067CDC3F8CAA2" modified="2019-05-08" version="1">MPHLPRPPLFFLSLPLPISFFPLLSIPSPSSIPFSSYLSPSFLYSLLPHLSPPLPSFSPFSPPPHLLHLLLSPQIHSTLLTSLSLPFPSSLSFLHTPHLSFPSYSFPSILSTSSSLPPLSHLLTLLSLLFPFPLQVVCHRPPPPFPLSSNLVLSPPALSSAPSIPHPPSFLHPLQPTLDPISLPLSLTTFLHVSTYHTPFPLSIFNLPLFLNHPPSLPYSSSSLLSCFSFLFPFSRLPSSSPSFLHSSSPSPPPCPSSSLPPLFLLSSSPPLSLFPLSSNLHLPPSLFPPFSHSSPFSPPLLLFSPFLHLLTSSPSLFPHSLSTSSPPLSSPLSSHSRPPPHLLSFSPLSSSSFLLSLPLSSLFPPSPLNPPRPHIPYLSAVHHNKDDRPRFYVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY61</accession>
    <name>A0A423TY61_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endoplasmic reticulum lectin 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ER lectin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_025437</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000978">
        <property type="protein sequence ID" value="ROT81404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY61"/>
    <dbReference type="STRING" id="6689.A0A423TY61"/>
    <dbReference type="OrthoDB" id="239053at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0430">Lectin</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MRH" evidence="9">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="21051" checksum="197F016300F43288" modified="2019-05-08" version="1">MCIHPEKVYKPGRRYVSHFYSGGTTCDLTGRPRQVEVKLKCKESQSPSSVTLYLLEPETCEYTLGVETSIICPLLQHADTLGLFTQSQGKEEAEGTIDPAILVEEIMQSQHPEGEVEEVEEEVEELEVVEEQQVVIVEEKVVMLVEEEGVEEGETGDEEGDVKGERLSQKEKSKGETQPSGTPREEGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZA0</accession>
    <name>A0A423TZA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Elongation factor 1-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_025060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000917">
        <property type="protein sequence ID" value="ROT81777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZA0"/>
    <dbReference type="STRING" id="6689.A0A423TZA0"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001857">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="5">
        <location>
            <begin position="5"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="192"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT81777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="271" mass="30005" checksum="AD3FB1C4E4C99EB3" modified="2019-05-08" version="1">MGKEKIHISIVVVGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKESSEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETNRFYVTIIDAPGHRDFIKNMITGTSQADCAVLITNTAVNRAAREGLFAPTATFRERRSARGNSLPQAFSGQLAEFTCRGRKDSGIPVHKAAISSGPSTVTCLRHGGLATTADATWRDPPPPRVSFNGDAPRRPTPAPAPPACLEPRDNIRRVWRRHRRESRHVTFTAAIKCEPVSHTRLCLPEARGLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U022</accession>
    <name>A0A423U022_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">I-connectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024764</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000886">
        <property type="protein sequence ID" value="ROT82067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U022"/>
    <dbReference type="STRING" id="6689.A0A423U022"/>
    <dbReference type="OrthoDB" id="6381907at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000425">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="110"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="256" mass="28396" checksum="16CCA8E4007DD419" modified="2019-05-08" version="1">MEPPKFIKPLHPQIVPEGEVAILEAEVTAKPEAEFKWYRHGQEITHDEEIEVQITSNNNKSSLVLGELFEDDSGDYTVTAQNPVGRASSTATLLVEGEGDEEAEPPSFDPPLTPIRVMDGEEVRFRCKVKGKPMPKLTWLQNGRPIAHHREVRLTQTPDGKAGLQILEVFPEDAGDYTCIARNKAGEARTTANLAVESYEYVPDSEAATTTSVSEKNIFSGPVSEEEETIEIEKTQTLTIQRQAPPRTSVTDLNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0S1</accession>
    <name>A0A423U0S1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Islet cell autoantigen 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000848">
        <property type="protein sequence ID" value="ROT82303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0S1"/>
    <dbReference type="STRING" id="6689.A0A423U0S1"/>
    <dbReference type="OrthoDB" id="2126778at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019904">
        <property type="term" value="F:protein domain specific binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051049">
        <property type="term" value="P:regulation of transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000068">
        <property type="entry name" value="Islet cell autoantigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010504">
        <property type="entry name" value="AH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024114">
        <property type="entry name" value="Islet_autoAg_Ica1/Ica1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006723">
        <property type="entry name" value="Islet_autoAg_Ica1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10164:SF4">
        <property type="entry name" value="GH23156P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10164">
        <property type="entry name" value="ISLET CELL AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06456">
        <property type="entry name" value="Arfaptin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04629">
        <property type="entry name" value="ICA69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01015">
        <property type="entry name" value="Arfaptin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01237">
        <property type="entry name" value="ICA69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50870">
        <property type="entry name" value="AH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AH" evidence="2">
        <location>
            <begin position="54"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="565" mass="63828" checksum="0A81F06FEF59AB7D" modified="2019-05-08" version="1">MTQQIHSYSGQSYDRWVERNSNSSAFGKVQKQFWFTKSAVIRKLGKKEDEHVVASDAELDAKIELFKAIESSTKDLQVLLADYQNKICIMAQEENAMGRLLKEYGKQDRSRAGKMMTAVGKSLSYTAQQRVALRNPLVRLFQEVDTFHTRAVEDTLITVTEMEKIRTEYRGALMWMKDISQNFNPDQYHQLEKFREVQATVKQKKAKFDRLKLKSLQKVDLLAASRCNMFSHALIVYQNNLITFSDKTSKTLNNVANNFKGYQPYDFQVIKELAEPPRRLEDDAKEEEENYKLDEDDNTFFNAEYHDDPDKKKQQNREKQGNRRTNKKVNGEKKSDSLLNLFDCADGEKSEELVSLGQVDREAPPSSKDKESDSSTSQIMDFLTNNPEVPDTEKDTQQMLKELFDSPVHQSLPVFGSTEVASGAAITPTKSNVDGGLLQGLNGLESDPFSLLQNQSNQQMQNMFLPSQLLDFGMQSWQQNTAHNTPNQPGVAQANVSNTKGSSPANSLSQSRHTAGGAHSAPSLNAAQKQEASKLDWYKVFQDIDPLADPANAIFSQASHDDKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1F3</accession>
    <name>A0A423U1F3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin repeat and SOCS box protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024302</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000810">
        <property type="protein sequence ID" value="ROT82529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1F3"/>
    <dbReference type="STRING" id="6689.A0A423U1F3"/>
    <dbReference type="OrthoDB" id="6378323at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070531">
        <property type="term" value="C:BRCA1-A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031436">
        <property type="term" value="C:BRCA1-BARD1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="302" mass="33301" checksum="84B3AC89AAAEE82E" modified="2019-05-08" version="1">MNNQVDSAHYILRSQSVHARRGTCRKRTQAMASLRLILCAAFAVVLLVSIGCGERQMTFERQGQADTALHCAAEEGHEAAAKKLIVKGADVNAKDKDGYTPLHLTAGNGHRAMVEMLIGKGAEPNAKADGGDTALHIAASQGHLHVLFTLVKLGAATKVKNGQGMTPKELLKGTSTTANYDMEIFKGISLIEIMEKYLAAEKGKASLRRENMSLQNKHKKELKSIKEDQRKRDADSQKMKKEIGALKDKIKAIEEEHKAELRNVAENQQEKEAEILRMQNEIVGLKETVASRDEKIKSLEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1Q4</accession>
    <name>A0A423U1Q4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000795">
        <property type="protein sequence ID" value="ROT82635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1Q4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="88868" checksum="DBB3B2CA50A237F2" modified="2019-05-08" version="1">MPGRGRPLRATRSSSQPSSRTSSPDHRASLIVVQGSDSQVQDAVRAVESEVTIMEEMVQRMTELIAQNREELLRRMEEMARTSEDRLQRLEDHLQGRTAPTEAVVSRSNGSQVPSAVQPEEPPADAPLPHNRQGASPPATRSSSPIHHVATREDLQEWQQQLEERERRLQRQERALQNQQLPGYRREEEAQPGLSYVRTAMSQQRITFDQQPSLISRDVIPYLVSRDSIPHFKGETSACEPLKRNQEVESYIRAIENLVRPATDDAYIRAARASCRGRAETIINSESFDGIQDWDTFKRQLRRKFRGTYSASDFFKVLYDHGMTERQAPMDFFLEVEASVFQGYRDHRGAVGEPSELIRRVFLAGLPSTLRDLLVLKDDCSPIQLAETARSFGTPGMASGTAVPTLATSLRTTSKRTTTSFDVALQTGHLVLETVMTCSLLPPHRHLLSLFPRLQYHGVMYGVNIIEVQPTAPGNAELLPVSLHHQPTLVSVVEGAVTCLVSAPFREARKEGFPTSLATLQEGTRTRSITVQTEPVQTTAAVTTPAVGGRPVVALSVDGKTLLCFIDTGSQVTLVKPSALEVIDPAKKLRHYASSKILQGVSGEPFHPAAEVTLSFNIKRSCATSPPIVADLSFHGDVLLGTDFLRRQDFHFADGSPITSWTAHPGRLVPDSGLSHLWERSTVFPSPRAITNSCNQPSGTQLPGIMYLLSGLALRTNSTSLREERQNPGGAAAGRDRCPVSSGCTLPRGLGSSTSATTEHRFLLQAEEESAFTTASAVTELKHFTKSLSLDGSVEEMEWDDFCRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U578</accession>
    <name>A0A423U578_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_022955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000631">
        <property type="protein sequence ID" value="ROT83873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6378913at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF12">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018981833" description="CUB domain-containing protein" evidence="4">
        <location>
            <begin position="26"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="97"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="314"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="363"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="363"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="549"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="607"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="642"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="694"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="740"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="787"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="808"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="820"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="844"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="865"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="914"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="984"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1023"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1035"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1054"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1078"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1122"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1141"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1161"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1182"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1200"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1224"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1237"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1249"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1466" mass="153922" checksum="E5CFBE5E36E00723" modified="2019-05-08" version="1">MSASALSSLLTATVLLTLVLPGVRSMSVADVGADGEELGRNSKFIFTLVKFPNVKCGSGLDAGTCVTGAECTARGGSVVGSCAKGYGVCCKITLTGCGGTVTRNNTLVLSTDYPSYYNEAKTCEYKVQFDDAPGHVCQIRYQHISNELVAPSSVGVCENDKLVFKEDTKSTYFCGKAPDNYQWNVATSGTSSPHTFTITTDSSSSNRRYAILVTWIPCSVRVPGTCGMYFEGITGSITSYNFNNGYYLAGLNYGICFRKEQGRSPSPFYSPPASAACSCSSIIFNPQHRSQLNPPFLLLPPLIAPLLTQKPQLTPPSPAAPFFTRTRQPTSHRPPPTFSPATQKPSFTPPALCSIPFCSTPDPPLLTAPHPPPMPPPLSRKQKPGAPPNHHLLTAPHCGSGSCSPAHPPSPAPSPSPSQHRSPASTRQPPLLLPPSPQPEAHSTPSSCSLPLLSRNTEAQLTPPSSCSLPLLPATKKPSSTPPLLLLPPPSPATQKPSSTPPPPAPSPATQKPSSLLLLPPLLPQHRSPSSTPPPPAPSPSPATQKPSSTPPPLLLPPLLPNTEAQLTPPPPPAPPPSPRNTEAQLTPPPPPAPPFSRNTEAQLNPLLPPPPQTQKPSSPPSSCSLPLLRNTEAQLNPPPSSCSLPLLPATQKPSSTPPSSCSLPFSRNTEAQLTPPPSSCSLPLLRNTEAFPLLPPPAPARTQPPPPPAPSPFSRNTEASANPPPSSSLPFSRNTEPSSTPPPPAPPLLPLPPPSSCSLPLLPQHRSPAPPPLLCSLPSPATQKPSSPPPLLLLPPPSSRNTEAQLNPPPLLLPPPSPATTEAPAQPPLLLLPSPFSATQKPSSPPPPPPLLPPSHRNTEAQLTPPPPPAPSPFSPQHRSPAQTPPLSSPSPFSRNTEAHSTPPLTPAPSPSPATQKPSSPPLSCSLPLLPATQKPSSTPPPPSCSLPLLPQHRSPAHPPPPAPSPFSRNTEAQLTPPPSSAPLPSSRTRASPAHPPPLLLLPPPSPANTESPALPPPPRCSLPFSRSTEAPAHAPPHPLPHPPLLPQHRSPAHPPPPPAPSPSPANTEAQLHPPSSCSPPFSPTQKPSYPPPSPSQHRSQLTPPPPPAPSPFSRNTEAQLPPPPPPAPPPLLPQHRSPAQPPPPPPAPSPFSRNTESPAHPPPLLLLPPPSPANTEAQLNPPPLLLLPPLLPQHRSPAHPPPPAPSPSPATQKPSSTPPPSSCSLPLLPQHRSPATPPPPPAPPLLPQQRSPLNPPSSCSLPLLPQHRSPAHPPPSCSLQPEAQLNPPPCSLPLSRNTEAQLNPPLLLLPPPFLPQTQKPSSPPPSSCSLPLLPQHRSPAHPPSSCSLPQHRSPSSPPSPPSPRQTTSIGGPTDVLRLPMGRRLNLVNDPSFPFSPILCPTLTSSAMYRNPSICFYPSEMVSDQTQGPFFINVYTAVDTDENRNTFVTDTRAGYQFDWEHNTCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6X6</accession>
    <name>A0A423U6X6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative periaxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000536">
        <property type="protein sequence ID" value="ROT84468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6X6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="911"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="933" mass="105702" checksum="A02D8379E9C129B5" modified="2019-05-08" version="1">MPTLTSCRNHILFCSTYTIYLYTEPFLCLPNTFSFPANPYLPVPNLFISLPRSLSIILNRTNSFLSPYQPSFSYRTLPFYLRRNVRLSLPNPFLSYRHNKSPPSFISTEPFLSLPYPSFRSRPFHSPTDPRFTWPNPFHSFTINPPFLPNPLPLDLAQPPSLFLNPSFSYRTLPFPFFFFFQPFLPRTNPSFPTEPLPFLPTLPFLPTFASPLHFRTEPLPFLPNLPFLATLPFLPTLPFLPNPPFLRQTLPFLPTLPFLPNPSFPTKPFLSCQPFLSCQPFLSYLTLPFLPNPSFPANPSFPTKPFLSYRTLPSFPPTLPFLPNPSLSYQTLPLLFPAKPFLPTEPFLSYRTLPFLPTLPFLQPFLSCQPFLSYRTLPFLPNPSFLPNLPFLPTLPFLPNLSFLTEPFLSYPFLNPSFPPNPSFPTEALPFLPSFPNPPCLFLPNPSFPSFPLPFLRTNPSFPNSETLLSCRTFLSCRPFLSYRTLPFLPTLSFYRTSFLQPFLSYRTLLCLPNLPSYRTLSFPTKPSFPTEPTFPCFLPYQTLPFLPDPSFPTEPFPFLTETLPFLPNPSFPTHASSFPTMPSFPPCPILSTMPLFSYHAPSFPTSPSSFPYHAPSSFPTMPHPFPPASFHFLYLPPSYHASSFPTMPLFLPCPIFLPCPLLFPTIAPSFYHAPSFPAPPFLPCPSFPTYPSFLPCPILSYHTPSSPTIPASFPTMPHPFLPCPFLSYQAPSFPTMPHPFLPCPSFPTMPPPFLPSPLLSYQAPSFPTMPPPFLPNLLFLPSPFFPTMPPPFLPCPSFPTIPSFPTMPPSFPTMPLLSYHAPSFPTMPPPIPTMPPPYPSFPTKPLLPTRPSFPTMPPPFLPNPSFPTKPHSFLPCPSFPTKPILSHALPPPHPPSPFFYLFSRCPVGVLHLFVFFPFPLFIFLFLCCALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U970</accession>
    <name>A0A423U970_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000350">
        <property type="protein sequence ID" value="ROT85249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U970"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="641" mass="69662" checksum="E26AB68C42AB22A0" modified="2019-05-08" version="1">MSVAFSQLHSTQHQHTASHIINSISQHLTALSVAFRSISSSHSIHSISQHAAHSITSSHSSISQLRHSISTAQHAHSISQHLTASRKTRQHSTAPQQHLTASLHLHSISTAFHSISVASPRHLGRVDSISRYLHSISTASQHLTASQQHLTASQQQYHISTAYSTAQQQDSTASHSNSISKHSTASHSISTASQQQLNSISTASQQHLTASRKRQHLNSITALNSISTATSTASQQHLNSIQSNLNSLNSISSISSRKTRQHSTASHSITASQQHLTASRKTRQHLTASLSDTEPTQTFNNISRCISHPCNTVNHISNHTSPFFASHNLTSPFFTSNLTLLPSRPVTSSNLGFSFLAQSLEPHFSLPRPVTSSNLSSPFLAQSHLRTSLLPSSPSHIFELTLLPSSPSHIFEPSPFSPSHIFEPHFSLPRPVTFSNLSSPFLAQSHFELSSPSSPVAFSNLTLLLLLPFTSSNPLLPYSPSHFEPHFSLLASHIFEPLFSLPRPVTSSNLTLLPSSPSHIFEPLFSLPRPVTFSNLTSPFLAQSHFRTSLLPSSPSPFSKPLFPPPRPVAFRTSHFSFFFPFTSSNLTSPFLAQSHLRTSTFSLLLPVTSSNLTLLPSSQANSPPSPPPGVSAPTSPESKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U995</accession>
    <name>A0A423U995_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_018267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000337">
        <property type="protein sequence ID" value="ROT85280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U995"/>
    <dbReference type="STRING" id="6689.A0A423U995"/>
    <dbReference type="OrthoDB" id="6371339at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="260"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT85280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="57452" checksum="37F50A8805B56AE9" modified="2019-05-08" version="1">MDGILGDLPFCAYVDDILIFSRDPNEHLQHLRVALKRLHNNGLVVRQDKCQFGATSVEFLGTRFRQQASHPFQIAHIMEPLYNSLAGKPKKLEWGLSNKSVRDHQDCPCISYNSHLPHTRHSTYPYHRRKLHCYHQPLVHAFSKPGDAWSDRQQRQLSSIAEFGCSIKYTPGTITSLQWKDVHIGGEGRTILCDVSTGRPRPLIPKSFRRKIFNLIHGLSHPSGRTTARLMKDKFIWHGMNKDIKQWARCCVACQMSKENFGSPCAGLDISVDVVGPLPPSDGAQYLFTATERSTRWPEAIPMQHTTTARDCAEALLHGWISRFGVPDDITSDPGPAFTSQLWTSLGELMGSTIHHTTSYNPEANDSEHLTKLRHAVEKYRPCTQTHSTSPQYLPKLIHSCKYVFVRNDAHRSPLTRPYRGPYAVLERNPKAYRLSIGGKSDWVSIDRLKPAYLEEKEPTPTTPLADNPAHTVPPSNAPAHVSHPEDKPFQISSRSGRLIRQPNRLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9P8</accession>
    <name>A0A423U9P8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_014660</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01000283">
        <property type="protein sequence ID" value="ROT85417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9P8"/>
    <dbReference type="STRING" id="6689.A0A423U9P8"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="7">
        <location>
            <begin position="13"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="8">
        <location>
            <begin position="212"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="302" mass="33811" checksum="07946878AE723CD2" modified="2019-05-08" version="1">MPTVTQLSYTDGQAQRQVEFRDTPVVHKGPGSIYVEKVMLSSDPDEFNLIKILLRQTRRPEIGDKFSSRHGQKGVTGLIVQQENLPFSDHGMYPDMIMNPHGFPSRMTVGKLMELLGSKAAALEGKFNYGTAFGGTSVKDIMEDLVKHGFNYQGKDMLYSGTTGEALKGYIFFGPVYYQKLKHMVMDKMHARSRGPRAVLTRQPTEGRARDGGLRLGEMERDCLIGHGASMLLLERLMISSDAFDVDVCNSCGLLGYSGWCHYCRSSANVSSIRIPYACKLLFQELQSMNIVPRLRLQNYCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9S9</accession>
    <name>A0A423U9S9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000271">
        <property type="protein sequence ID" value="ROT85462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9S9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="473" mass="51332" checksum="4588F958ED6E7F9E" modified="2019-05-08" version="1">MLAGLSGTRPRGSGLISFLPPSLLVFSSSSLVFLSVSCLPSLLSSFLRLSCFLPPSLLSSLSCLPSSVSLAPSLLSVSRLLPPSLLSSFLRLSCLPSSVSLVFFPPSLFLPRLFLSSFLRLSCILPPSLLSSFLSLLYLLPSFLLSCLLPSVSLPSSVSLVFLPRPSASFLVSLVFLSSVSLVFLPPSLLPSFLLLLSSSSVLSCLPSSVSLVFFFRLSCLSFLLSLVFLPPFSLVFLPPSILSPFSISLLSRLSLPSSVSFLPPSLVFLPPSLSSFLISLVFFLRFSVPSPSLLSSFLRLSCLPSSVSLVFLPPFLLSSFLRLSCLPSSVSLVVLPPSLLSSFLRLSLSSFLRLLSSFLRLFVFLPPFSCLPSSVSLVFLPPSLLYSFLRLSCLPSSVSLVFLPPSLLSSFLDLSNLHISSLFISLFLSFPHFSLHRLPPSFLSHFLPSLFLYLYFPLSFTFTIALHSSYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9W7</accession>
    <name>A0A423U9W7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inositol 1,4,5-trisphosphate/ryanodine receptor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000259">
        <property type="protein sequence ID" value="ROT85514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9W7"/>
    <dbReference type="STRING" id="6689.A0A423U9W7"/>
    <dbReference type="OrthoDB" id="300855at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034704">
        <property type="term" value="C:calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033017">
        <property type="term" value="C:sarcoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005790">
        <property type="term" value="C:smooth endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005219">
        <property type="term" value="F:ryanodine-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014808">
        <property type="term" value="P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006941">
        <property type="term" value="P:striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014821">
        <property type="entry name" value="Ins145_P3_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015925">
        <property type="entry name" value="Ryanodine_IP3_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399">
        <property type="entry name" value="B30.2/SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399:SF8">
        <property type="entry name" value="B30.2_SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08709">
        <property type="entry name" value="Ins145_P3_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol 1,4,5-trisphosphate/ryanodine receptor" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="28912" checksum="311BC76CBA71A3D7" modified="2019-05-08" version="1">MVCLSCTATGERVCLAAEGFGNRTCFLENIADKNNPPDLSQGVFVIEQALSVRALQELVTAAANEEVSPPLSFPRPFLSPSPPIPFPRNVPENRQAKFCQHFPRLKETPFYLARIRRRFKNKVGRENVDTEVTALLKLQGGESGSSVPRRRTVPSTCNGTGETPKGCSIRQRLEGREPASDGFDNGQEADTGGRLECIPLPPPPPASPQMNSPKCQPGGVTWLFTVPTDPPVPSGSSHGVHTAAGFLPNENRRALRERGCSIFIPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-02-13" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3G2YPU5</accession>
    <name>A0A3G2YPU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Heat shock protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_005222</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2018-09" db="EMBL/GenBank/DDBJ databases">
            <title>Heat shock protein 40 (HSP40) in Pacific white shrimp (Litopenaeus vannamei): Molecular cloning, tissue distribution and ontogeny, response to temperature, acidity/alkalinity and salinity stresses, and potential role in ovarian development.</title>
            <authorList>
                <person name="Chen T."/>
                <person name="Lu T."/>
                <person name="Li H."/>
                <person name="Hu C."/>
                <person name="Ren C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="MH932106">
        <property type="protein sequence ID" value="AYP27278.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3G2YPU5"/>
    <dbReference type="STRING" id="6689.A0A3G2YPU5"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000014">
        <property type="entry name" value="dnaJ homolog subfamily A member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000005">
        <property type="entry name" value="DnaJ homolog subfamily A member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="14" id="KW-0346">Stress response</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="12">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="13">
        <location>
            <begin position="122"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="10">
        <location>
            <begin position="122"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="365"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="AYP27278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="44369" checksum="8A7FD78CECD28C09" modified="2019-02-13" version="1">MVKETGYYDILGVKPTATTEELKKAYRKLALKYHPDKNPNEGEKFKLISQAYEVLSNEEKRAIYDQGGEQALKEGGTGGGGFTSPMDIFEMFFGGGSRRSREKKVKDVIHQMSVSLEELYNGAVRKLALQKHVICSKCEGQGGKKPPEKCPSCRGTGMQVRIQQLGPGMVSQVQSMCGECRGQGERINPKDRCKTCEGRKVVKDRKILEVHVDKGMEDGQKVVFSGEGDQEPGLEPGDIIIVLDEKEHATFKRVNSDLTMQMHISLVEALCGFQKPIKTLDDRTIVISAIPGEVIKNAEVKSVLGEGMPQYKNPFEKGRLLIQFLVDFPPHISSDRIAKLEKILPARPEVMIPDDCEECELAEIDRSQRSRRHNMMHDDDDDDHGPRQQHLQCQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LR50</accession>
    <name>A0A3R7LR50_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative centrosomal protein of 89 kDa-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003764">
        <property type="protein sequence ID" value="ROT62209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LR50"/>
    <dbReference type="STRING" id="6689.A0A3R7LR50"/>
    <dbReference type="OrthoDB" id="6369898at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097539">
        <property type="term" value="C:ciliary transition fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033545">
        <property type="entry name" value="CEP89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36170">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 89 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36170:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 89 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="280"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="43721" checksum="427496051A419D74" modified="2019-04-10" version="1">MADERAVIMRYHLKYGRIREENIGSTKKDLSHDSIYKLGALLTAYDEIILERDEALKSNLEKFEKLMVNVDAVTAENEKLHQRVQKLQQEAPMGSEEAEMVAADAKLLLEERELLLQEVRTLHQQQQEESICYQQKVAKLQQHLEDSEARVATLSSELDSLRTEAGQLERQCKKIQQQLQESVSKEEHQLAVDECQRLFEKLRKTYTEESGDLKGKMRAVKQEKQNLAEKLTDSSAYVHNLSVQVSGLKGSLRKTESRVKRREKALQVVQTTARVAQTRLKSLSEVCSKLLEDREKLLEALATQRKETDELSKELTLRSAAVGALSQKLKEERINWSSKMAECEGGRQAAKAAWKRSTKENSHLRTLIAAKDDTITSLIADYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRT4</accession>
    <name>A0A3R7LRT4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003563">
        <property type="protein sequence ID" value="ROT62691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRT4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003882">
        <property type="entry name" value="Pistil_extensin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01218">
        <property type="entry name" value="PSTLEXTENSIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="43491" checksum="231A1C330F154B46" modified="2019-04-10" version="1">MCILINISRYKHIQYIKLNIYPPLPTYPTHPPPLSPLTSSPPHITSSPPSSLPPPPHPPLLLPHSSLPSPLSPLPLIPSPLAPTHPPPSPPLPLSPPLLSPLTPSSPPLLPLPTHPSPPPLSPLTPHPSSPPSPPPPNPLPLPLPLSHSHSLPSPLPLLLLSHPPTHPTPHPLSLPPFPPHPSPLPLPSPPSPHRPTVATQTFSSDAPLLPHTYPTSRPPPHILLPPLPPTPHPLPPSPPLPIGRNYGSSSHTPTLPPLLFASPSAGERATRLRLCAPTTRRAHTPRGLSAASCHKDHASPPQPPRARLAERRVRNMFKVWLHFLSSSSSSAEDIAPDQHVFRRKRRRAAIAPFPPRCDPVRGTPSAPPAEHTARVAPAGGKQRVVVTTGGRYYRWSFKRRSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSR6</accession>
    <name>A0A3R7LSR6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020238</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003912">
        <property type="protein sequence ID" value="ROT61948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7LSR6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="935"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1237"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1419"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1681"/>
            <end position="2080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1256"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1420"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1514"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1596"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1683"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1721"/>
            <end position="1733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1738"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1756"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1806"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1837"/>
            <end position="1860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1866"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1888"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1933"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1954"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1990"/>
            <end position="2012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2024"/>
            <end position="2053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2068"/>
            <end position="2080"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2164" mass="245680" checksum="23A517194604D74B" modified="2019-04-10" version="1">MTSTAALTNSWAPGQVVEDRKHFPRLSFLKSELRVSYEYLSSAYRNVDPEAAFAPRLPGRKFPKFWKTSRLRCRKGAKKPATYREYKEHYEFLIGSRIQLIEDVIAILHPGHVTSEAWAIKEDENLPSGLSESLSSGLSALSGDFWLEHVRRAGHGVQTRKRRNHRTLYLVFQTPSRDELRLLFFVQRVYPRQDIPQFSLILLLTVGIAGGIGLTSTGLTDKDAYDLKRIIVYSFTLTLVLVAAEPRRRQGIMATKGIAILLAALSVCLTCLWKLEKEVFLAKQKELGLQSLEIEKTISRIPRWFATDEYIAALQCIVPQHPWYLPDFSVSQRQLACNEESLEIYQALSDEAEDTAAHVSRVVGTICSILVGTLWASSDSSASAPWPASRIRRSRRSTRKTMSSPSRCTRPTRRRRTTSSSLRAARPSSSPRTRPTRRRRTTSSPERRLVIPFALHEADAEEEDDIEEDDIVIPFDEADAERRRTTSSSPSRCTRPTLQEEDEVEGEDEGDAEEERGDAEEEDDIVIPSRCTRPTRRRRTTSSSLRAARGDAEEEDDIVIPSRCTRPTRRREDDIVIPFALHEADAEEVRQEERRRGGGGRHRHPFAPRGRRGGGGRHRHPFALHEADAEEEDDIVIPFALHEADAEEEDDIVIPSRCTRPTRRGGRHAEEGGRGDAEEEDDIVIPFALHEARREEEDDETRPTRRRRTTSSSPSRCTRPTRRRRTTSSRRRGGGGRNEADAEEEGHRHPLRAARGRRGGGGRHRHPFALHEADAEEEDDIVIPSRCTRPTRRRRTTSSSPSRCTRPTRRRRTTSSSPSLHEADAEEEDDIVIPFAVHEADAEEEDDIADAEEEDDIVIPFALHEADAEEEDDIVIPFALHEADAEEEDDIVIPFALHEADAEEEDDIVIPFALHEADAEEEDDIVIPFALHEADARRRTTSSSPSLHEADAEEEDEVDAEEEDEVDARRRTRPTRRRRTTSSSPSRCTRRRGEEDDIVIPSRCTRPTRRRRTTRRGSTRRKEDEVDRRGGGGLPRGRRGGGGRHRHPLRAARGRRGGGGRHRHPLRAARGRRGGGGRRRVTSRRRRTRSTRRRRTIVIPFDEADAEEEDDIVIPFAVHEADAEEEDDIVIPFAVHEADAEEEDDIVIPFAVHEADAEEEDDIDDEADAEEEDDIVIPSRCTRPTRRRRTSSRGRREEEDDIVIPFALHEADAEEEDDIVIPFACTRPTRRRRTIVIPSTRPTRRRRTTSSSLRAARGRRGGGGRHRHPLRGARGRRGGGGRHRHPLRAARGRRGGGGRHRHPLRAARGSRRRRTTSGRRGGGGRHRHPLRGARGRRGGGGRHRHPLRAARGRRGGGGRHRHPFAVHEADAEEEDDIVIPFALHEADAEEEDDIVIPFALHEADAEEEDDIVIPFALHEDAEEEDEVDADDIADAEEETNRHPLRGARGRREEEDDIVIPFALHEADAEEEDDIVIPSRCTRPTRRRRTTSSSPSRCTRPTRRRRTTSSSLRGARGRRGGGGRHRHPLRHEADAEEEDDIVIPFACTRPTRRRRTTSSSPSRCTRPTRRRRTTSSSPSRCTRPTRRRRTTSSSLRARGRRGGGGRHRHPLRVHEADAEEEDDIVIPFAVHGPTRRRRTTSSSPSRCTRRRGGEDDIVIPFALHEADAEEEDDIVIPFAVHEADAEEEDDIELEGEEVVDEQEEDDIVVRSSSPGAGGGGGGRRRAGRGRRRHPLPAQELEEEEVVDEQEEDDVVIPRRRSSRERRSSTSRKRTTSSSPPRRRSSRRGGRRRAGRGRRRHPLPAQELEGEEVVDEQEEDDVVIPSPAQELEEEESSTSRKRTTSRGRGGRRRAGRGRRRHPSPAQELEGEEVVDEQEEDDVVIPSPAQELEEEEVVDEQEEDDIELEGEEVVDEQEEDDVVIPSPAQELEERRCRRRAGRGRRRHPLPGAGARGRGGRRRAGRGRRRARGRGGRRRAGRGRRRHPSPAQELEGEEVVDEQEEDDVELEGEEVVDERKRTTSSSPPRRRSSRERRSSTSRKRTTSSSPPRRRSSRERRSSIVIPSPAQSSRRRRSSTSRKRTTIIEEEEVVDEQEEDDVVIPFVVVVIPSPAQEEGEEVVDEDDVIPFPIHEVVVDDEDDVIPFPIHEVVEDDVIPMRSWRTMRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTM8</accession>
    <name>A0A3R7LTM8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_018017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003332">
        <property type="protein sequence ID" value="ROT64074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTM8"/>
    <dbReference type="STRING" id="6689.A0A3R7LTM8"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="107"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="27976" checksum="BB42E52BCCC02A57" modified="2019-04-10" version="1">MNHYITILVPGFNVETVEYKNISFTVWDVGGQVKLRPSVEALLPEHRRRRLRVGQQRRREAAGGQGGAGRHRECWGRPRRRPSSSRPLLFLLESEEVAGVPLLVVANKQDLPGALSVPQLSEGLDLRRHDRPWHVQPTCAITSEGVYEALDWLARELAYTGTPGASPYAAGPQRGHGRGIRTREDPNTGRVEHKDAFEVTDELSKQSQNQKMDLTEEENAGFTKKQSHFAFFLSSPTQRDISDEDFPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVF7</accession>
    <name>A0A3R7LVF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003310">
        <property type="protein sequence ID" value="ROT64174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVF7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="41915" checksum="42C6D83C572B5F4C" modified="2019-04-10" version="1">MKLDSTLSSPPGDARKPRLDSNPRLTPGEARLEPSPTARRSSTRTLASPPGEALEPSPHRPEKLDSNPRLTELEPSPHRPRSSTRTLASPPGENPRLEPPRSPPGEARLEPSPHRPEKLDSTLDRRTRLETLASPPGEARLEPSPHARRSSTRTLASPPGEARLEPSPHRPEKLDSNPRLTAGEARLEPSPHRPEKLDSNPRLTARRSSTRTLASPPGEARLEPSPHRPEKLDSNPRETEPSPHRRRKLDSNPPQPPGEARLEPSPHRRRSSTSPHARSTLASPPEKLDSNPRLTARRSSTRTLASVCLSPPGEARLEPSPHRLDRLTARRKLDSNPRLTARRSSTRTLASRSSTRTLSSVCLSPPGEAQTHAETYRLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M007</accession>
    <name>A0A3R7M007_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Actin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012584</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M007"/>
    <dbReference type="STRING" id="6689.A0A3R7M007"/>
    <dbReference type="OrthoDB" id="6331703at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="41323" checksum="68B9E7429E7F8DFA" modified="2019-04-10" version="1">MCDDDVSPPNGKGVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEESPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDTGDGVTHTVPIYEGYALPHAILRLDLAGRDLTAYLMKIMTERGYSFTTTAEREIVRDIKEKLCYVALDFESEMNVAAASSSLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESVGIHETVYNSIMRCDIDIRKDLFANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQSMWITKEEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M071</accession>
    <name>A0A3R7M071_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_018356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003386">
        <property type="protein sequence ID" value="ROT63742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M071"/>
    <dbReference type="OrthoDB" id="6376360at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT63742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="64886" checksum="FBBEFC9D66A205B8" modified="2019-04-10" version="1">MFKRKTKVSIVILSFVVYFCHQILVPDSKISFSEGRSLLAGSAWDPGELNKEQEGQCRALFKISGVYHPKNNHRSGAKSSENVPSWYTGSEFVEMAKRRVRTFLEDISRRPGGPSTQDYRSLGSDLPRLLYYRREKAESSLRGTLASSLTKSDEELVPVSRMKRPLDTQKDTEKVFFMDRFQTTDGDLPFVPCRVRRYTRTDINACFRKRLEKKKQFTMFFLGDSKIRNMVVEFLNTTSYLDYTVFRKNESWPWTVYRAMLEDEDIRFSDFEVTAASHPGLRVIFKFRRFWEWRDIDSSDEVKILKKWAEGTQPVPDLLVVGYTSWMFYTITHRLQYDPNFQLDVLDILMRVHEVVVPLLQRVADRTRVLVHADTRLRPHSQSKKPHHRLAMNAVFQDFMEDWSEMMFRFFEKFGRTRLTKRRRLVARRMPLEGGLEHMFHVVEEITSGGRPSAGFDDAPPPQRTQVDAVRDHLLPDSNGLWWWDTSLPLNMAAITECSDLHNRNLTHLPQYSDPVLRCEDHHHSGTATLHFEVHMLLNLLCNSHLAVSPRFCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1M7</accession>
    <name>A0A3R7M1M7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ras-related protein Rab-34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003188">
        <property type="protein sequence ID" value="ROT64794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1M7"/>
    <dbReference type="STRING" id="6689.A0A3R7M1M7"/>
    <dbReference type="OrthoDB" id="413584at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="133" mass="14627" checksum="DD79137613FB8F73" modified="2019-04-10" version="1" fragment="single">MVVFDVTNVVTLAHTAQWLEEAREANINSCPLVFLVGTKRDLMSEGAYNQIEAQARRVAHGLGAEYWAVSSKTGDNVEALFMRLAALTFNRDVLQEVKGCDTRKSSGTVKIGERLDDTYETAKKSKCASGHCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1W7</accession>
    <name>A0A3R7M1W7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative intraflagellar transport protein 27-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002402">
        <property type="protein sequence ID" value="ROT70654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1W7"/>
    <dbReference type="STRING" id="6689.A0A3R7M1W7"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="21492" checksum="8DC15B91A8B30D29" modified="2019-04-10" version="1">MTMNNIIRTKCIVAGDSTVGKSSIVQSFLTEGSQFPKNYNMTLGLDIQTRLINVPDTSYSVELYLYDFSGKEFYRDLVLKMSSQPSLVFMVYDATSESSFKKVVDIYTQIKEETKMSTLKGVLFANKTDLTTRRRVSPKAGNDLSQSLGLMYFEGSAKDHAGVDEPFFYLVNEWFKMYTDKTQSFKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2C4</accession>
    <name>A0A3R7M2C4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011903</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002509">
        <property type="protein sequence ID" value="ROT69857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2C4"/>
    <dbReference type="STRING" id="6689.A0A3R7M2C4"/>
    <dbReference type="OrthoDB" id="6364028at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="215" mass="23578" checksum="DB98FD0689BBDAE4" modified="2019-04-10" version="1" fragment="single">RLLTQAARLTKGRHGAQRTRPLATRPVPHARSLTLNVLSGSSGASVNAQDVSGKSVLHTAVRQGSPMVGLLVDRGASVVCRDSKNGRTPIHIAAELGAKEILEMLLQKCPKGVDIKDGNRMTPLHFAAERGHHNCCQILLRHGASPLARNKLNETALHIAVRNCYKLTCEILLSHEHDLNKQRHNTDSRRSYALRLAKNSMPKRSCSSCWRGGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3D1</accession>
    <name>A0A3R7M3D1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3D1"/>
    <dbReference type="OrthoDB" id="196393at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="606" mass="65415" checksum="3642C9E48104FEB4" modified="2019-04-10" version="1">MEFHGVTKMQIPHNPRIWTEPGLFFSFPLFPWSPFSSPFYLLPIFFRYLSSRHLYFLSLSPFLFLLSLVLSPSNSLQLSSIYLLLPFLLFPSSPSRSFSLTSPSIYFPVPPQLPSSILFSHLFSPPLPSIFFPSSYSLFRFPSPPVPSLAISLSSHHLSSRHFFLPFPSISLISLSPLRRPSSVHGLYVKEITEGRSVFGLFSPTSELRLILRQDHFVNGQVKLTCSSTISHVYQEYSHVAITMTGFKTVAPSQKLYGKASGGGEQTRVKAQLTCRKLAPSSLPPLSSSAGNSCPPLSSSAGNSVLSLLFCRKLCLLSPLLQETRALLTPSSLLSAGNSLLSPLLQENSSPLLQALSSSAGNSPPLSSSAGNSCPPLSSSAGNSSSLLFCRKLMSSSLLFCRKLMSSSLSSAGNSCPPLSSSAGNSCPPLSSSAGNSRPPHSLLSPLLQETLLSPLLSLLPHVLFSLLSSAGHSRFLFCRTFTPSSLLFCRKLTPSSLLSHRLHVGRQLIPGHHIRHTPDGEVVLRQRPSSGQDISLQDSSAGGTLCPIKTSFSFLPGRCVCHALASLYRLGRGSPSPVPLTPRWRLLPRAGPGGLPRGGILFHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4A8</accession>
    <name>A0A3R7M4A8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Histone-lysine N-methyltransferase Suv4-20</fullName>
            <ecNumber evidence="3">2.1.1.362</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_015136</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61992"/>
            <dbReference type="Rhea" id="RHEA-COMP:15556"/>
            <dbReference type="Rhea" id="RHEA-COMP:15998"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60348"/>
            <dbReference type="Rhea" id="RHEA-COMP:15555"/>
            <dbReference type="Rhea" id="RHEA-COMP:15556"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="2.1.1.362"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.362" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002883">
        <property type="protein sequence ID" value="ROT66829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4A8"/>
    <dbReference type="STRING" id="6689.A0A3R7M4A8"/>
    <dbReference type="OrthoDB" id="6627536at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140941">
        <property type="term" value="F:histone H4K20me methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1700:FF:000001">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000006">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025790">
        <property type="entry name" value="Suv4-20_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51570">
        <property type="entry name" value="SAM_MT43_SUVAR420_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 17" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="16">
        <location>
            <begin position="125"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00071597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT66829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="255" mass="28852" checksum="3E2C110ACCD3B6E3" modified="2019-04-10" version="1">MVVAQGGRLMRGGGMATTGCGMTPKELSDNDDLATALVLDQYLGFATHKMNVRYRPLRGSKEELGQIIEDFIQHQDYEKAFKQLVSGDWMPWTFFITKNKHLQAAFKEHVFRYLRVFDKDSGFVVKPCYRYSMEGCVGAQPGSGEYKNEQIGYLVGCIAELSEDEETQLLHPGKNDFSVMYSCRKNCAQLWLGPAAFINHDCRANCKFTATGRGTACVKVLRDIEVGEEITCFYGEDFFGDNNSYCECLTCERYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5G2</accession>
    <name>A0A3R7M5G2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002141">
        <property type="protein sequence ID" value="ROT72513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5G2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="41466" checksum="8EF82CCE8AB1157E" modified="2019-04-10" version="1">MPLSLVCVRSFSLSLLRLFFVVFSLSLSLSLSLSHLLLSHPALSVSSLIASLLSFASPPLPCPPSSLSVMLLLSRLSLSLCSSLLSLSLFVSRLLLSLSTLLSLSLNLSLSPSSSLTLMVCSVAACTCYFSPLDGGLSLVPLCCRLLVDPPPRFLRLASASSSFLSLSSLSSHLLSSRSLFLSGSLLSSSLSSLRLLSLSLSLVSSHLSLFSPSLFALSLSLHPSSSSYPDPYLVVLIFFPLGACMSNSSPLFSLLSPSPHPSSFLLLLPSLNCSPSLSLSLYRRISSRLILCSLSLISARLSSLSFRSSLALSHFLFRACSRSASLSSLPPTSRPSLLSLLLPLIVDPHRLISIYNWSVSSCFVLSPSLSFSLSFRACLPPPIASLNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M698</accession>
    <name>A0A3R7M698_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_008453</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M698"/>
    <dbReference type="STRING" id="6689.A0A3R7M698"/>
    <dbReference type="OrthoDB" id="6376466at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000702">
        <property type="entry name" value="Transcription factor E4F1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001732">
        <property type="entry name" value="Zgc:162936"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051497">
        <property type="entry name" value="Dev/Hematopoietic_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45993">
        <property type="entry name" value="B-CELL LYMPHOMA/LEUKEMIA 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45993:SF6">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13909">
        <property type="entry name" value="zf-H2C2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT73137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="101" mass="10993" checksum="0BCF5980CE5222BC" modified="2019-04-10" version="1">MWAAPLPGALVPAPPPRPEGGLDNSSLRPHVCQYCGYSFCRPSQLATHIRIHTGEKPYRCTVCSYSAAQKGNMRRHMHLVHGIVVESNFAPSSLGAPKETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8E1</accession>
    <name>A0A3R7M8E1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein mS26</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">28S ribosomal protein S26, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_011915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002509">
        <property type="protein sequence ID" value="ROT69869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8E1"/>
    <dbReference type="STRING" id="6689.A0A3R7M8E1"/>
    <dbReference type="OrthoDB" id="5988811at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026140">
        <property type="entry name" value="Ribosomal_mS26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21035">
        <property type="entry name" value="28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21035:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14943">
        <property type="entry name" value="MRP-S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT69869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="229" mass="26543" checksum="B0E7E6EA0FB34372" modified="2019-04-10" version="1">MLPLGQTNILTAGYIGKIWYPVGEVAVSLGGVQSVRWRKPRWLPTAKSRLFTIPKRPVIPVEETREIQRLYNNYRTSLRAVRHHLREEYLRTSATSEVALQQAAEEEAEHQRLMEYNRMENERIAALREIRIKKELEDDLARVAASKQKLAEQAAIKQEEALRIITETQELVKTFIKRENLEKAIEHALANPVDYNSAIDHEGHIYRGRNTKVQDVPEEDREKLARASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MA11</accession>
    <name>A0A3R7MA11_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-induced degradation protein 4-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001692">
        <property type="protein sequence ID" value="ROT76120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MA11"/>
    <dbReference type="STRING" id="6689.A0A3R7MA11"/>
    <dbReference type="OrthoDB" id="62at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="24049" checksum="77D8EEEBF23DEB7A" modified="2019-04-10" version="1">MPVKTEMASMDPPPPANSGQPGVTRSLLYNGSRFQGHQKSKGQSYDVEVVLQHVDEANSYLCGYLKIKGLTEEYPTLTTFFDGEIISAKFPFLTRKWDADEEVDKKHWGKFPPFYQYTKNFNSDSFDYNVLKDSEHVFMRWKEHFLVPDHTVKDINGASFAGFYYICFQKSTATIDGYYYHRTSEWYQSLNLTHVPEHSVQIYEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDM0</accession>
    <name>A0A3R7MDM0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Metalloendopeptidase</fullName>
            <ecNumber evidence="10">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_001440</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01001185">
        <property type="protein sequence ID" value="ROT79816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDM0"/>
    <dbReference type="OrthoDB" id="6378629at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="13">
        <location>
            <begin position="103"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="12">
        <location>
            <begin position="396"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="12">
        <location>
            <begin position="891"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="609"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="662"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="614"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="662"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT79816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="969" mass="109270" checksum="09798C4CB68C8BC0" modified="2019-04-10" version="1">MWTKRFTQIFATLSIPWRRGFTQILAHIILWTRGFAQILARIIPWRRGSPDLSTYNVDEMYLRGDTEDSGPVEEPFEQTNPDVVDGKNLFEKDIMLTEAQWEQVLARKGLAAESRRWPEDASGTPRVKYPLRRRQSPSIPYPLFPTPSNPLSENVDQQAVLAGIAHWETHTCVRFDLITDANQPHLMFRQLSGCWSYIGYLPEYFPRGQNISIGLNCGMYHIIPCDPVSVEKSIPLGTVAHEIGHSLGWYHEQSRPDRDLFVHVNSQNVQSGRLGNFHKQSDTEVNNQNVPYDLRSVMHYGGTYFSINEHLTLATVDPRDQGLIGKRVGFSHMDILIANRMYHCIDKWLENCGLTADPCQNNGFTGESCTCVCPEGTTGTNCETVTGDYHAAYRSACNELITSPTTISSPNYPNKYPAGVTCAKWIKAPENMIPKVTFTDFRLTACANKWDFLEIRTNDLFDGDFYCENQIAAGTSFVGTSRELILMFYTRSNRGYGWEADVTFFDPSTTTTTTPEPTTTTTTYYYNDYQSHNYRTTTRDLQLQLQSLQRLQLQSLQRLPQLQSLQRLPQLQNLQRLPQLQSLQRLHNSEPQLLPHSRAYNDYHKELQRLPNSTTTPEPTTTTTTPEPTTTTTTPNPQLHNSRAYNGLQRDLPQLQSLQQLQSLQRATTTTTTPEPTTTTTTPEPTTTTTTPEPTTTTTTPEPTTTTTTPEPTTTTTTPEPTTTTTTPEPTTTTTPEPTTTTTTPEPTTTTTTPEPTTTAPEITTTGPTNDNASCTLYSFDDKVDWTSPYFGVADYPNDFKCGIVGYYDGPLMAKYTFNTFQLEGKSRRRNELCHDYVDIPIPYSRSMRFCGSQTGYQNVPNFRFSTEFVTDSSITDVGYNISISWEITDCHTVIQLSKKDSRGTISSPNYPSDYPDQAACEWWIVAPAGKKVTLQFRDVQVNNPDCEAFYIAVDRSGSGNYLPENSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFG4</accession>
    <name>A0A3R7MFG4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Star-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000157</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001020">
        <property type="protein sequence ID" value="ROT81103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFG4"/>
    <dbReference type="OrthoDB" id="6357215at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="121"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="469"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="689" mass="78257" checksum="2D7D2A2CE6E8F269" modified="2019-04-10" version="1">MGSRLLRKVLVFKESPCAGGCFVFLLMIAFSLFMSLSFVMTDNESNTFLEQLRGPPGAEDPRVLEVLKKHYLLPPPVSMPYNLTSGDATSRYFLKLVGWDFIHRHVRQLFAQQRGGFFVEAGALDGQFISNTLWLEKERGWTGLLIEPDALSFRHLQWRRRRAWISHSCIAPGQHPREAAFESMGRTKKGLLESGHWLYRANTREYNEFSSIADDISRTSFKSYSKVQCFPLASYLAALNVTKVDFLSLDIQGGEWEVIHSLPLDRITIRAMVVEHLNTRVDLEEARNFDAVFAAYMKELGYRLLDLDAKANYVFVLEKDAALAAAAAAAGSQGKAGEARRRTTMHLRPLSWQSNCRNRVHSRCRRVVLVVAEVVVAAAVLAVCVVSRRYYAVSCTSLDRLKGPLAAEDPFVLETLRNHYLLPPPSGSYNLTSLDKKDRLIHDRLGWDFIHRHVRQLFAQQRGGFFVEAGALDGQFISNTLWLEKERGWTGLLIEPDALSFRHLQWRRRRAWISHSCIAPGQHPREAVFESMQSRVHVPTSVWMFRSNTKEIDTPFAAIEDELGFFSSKSYSKVQCFPLASYLAALNVSKVDFLSLDIQGGEWEVIHSLPLDRITIRAMAVEYFNTRADESRRMARDEAFVSYMKDLGYILLALDDLANYIFVLARDPALEPSLDPRSNTTLARNESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGB0</accession>
    <name>A0A3R7MGB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Repetitive proline-rich cell wall protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000909">
        <property type="protein sequence ID" value="ROT81870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGB0"/>
    <dbReference type="OrthoDB" id="6423516at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36162:SF20">
        <property type="entry name" value="GLUTAMINE-RICH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018570026" evidence="2">
        <location>
            <begin position="24"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="882"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="915" mass="100482" checksum="01667DA0546F2741" modified="2019-04-10" version="1">MAMRVSLVRTCLMVTVLQALVSADVNTTDPSQTNSTKPLHPTPTPSGAATQGLAQTPTSSPTQTPKDTDDVPAKNTTHKSEEPTQKQRPASQPSLSTRPATREPSSAPAGLEASLDEPTPPLPLPQPLRALQGRTLPQREEVAPRKRSLLPTRRGQGRPQQHSGSGSSPLASDGPRGHAGAARVRRAEVLRLLPDGRRQTVNYEADHTKGYMSEVEYNNEKTGARPIGTGGRPIGIGGRPIGTGGKPTGTGGRPTGTGGKPTGTGGRPIGGSGRPSVSHGPPSGGNRFRLPTGSSNQIQTRPNNINRYQPPAGSTNTKFQPPSSNNNIKYQSASGGSSPTQSSAGGINRYQAPQRGSTPNKPPKDTGSQYQPPQNTGSQSQPAKSTITKLKPAKDFGNKFQSSQNDGNQYQPPQENDNQHQPPRPVGNQYQPPKDVGKKNQPLKDVSNQYQPPQEVGNQLEPPQEVGNQYQPPQSFNQYQPPQEVGNQYQPPQENPGSWQPYQPPQEVGNQYQPPRHHRRSWQPVPTTTGSGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPQEVGNQYQPPQEVGNQYQPHRKLATSTNTTGEVGNQYQQPQEVGNQYQPPQEVGNQYQPPQEVGNQYQPPQEAGNQYQPPQEAGNQYQPPQEVGNQYQPPQEVGNQYQPPQEFGNQLPQEVGNQYQSPQEFGNQLPQEVGNQYQPPQEVGNQYQPPQDIGNQYQPPQDIGNQYQPPQEAGNQYQLPQDIGSQYQPPQNVGNQYQPPQDIGNQFQQPQDVGNQYHLPPVVNTQYSAPTNIEAQYQVSKSDSIRYQNSRAQKQVVADEYQQPKESSSDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGB1</accession>
    <name>A0A3R7MGB1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001052">
        <property type="protein sequence ID" value="ROT80906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGB1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="712"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="902"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="971"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1010" mass="110102" checksum="DB5E9DCF1153F522" modified="2019-04-10" version="1">MEPRQTCDTLGKSNKGRIHSAEDTPVKTSGSTLHEHTPVKTSDPLCTKTPPVKTSGSTLPEDTPCEDDPLCPKTPPVKTSGSTLHEDTPVKTSRSTLPEDTPCEDVRIHSARNTPVKTSGSTLPKTPPVKTSGSTLPKTPPVKTSGSTLHEDTPCEDDPLCPKTHPVKTSGSTLHEDTPVKTSGSTLPKTPPVKTSGSTLPEHTPVKTSGSTLPETHPCEDVRIHSAQDTPCEDVRIHSAEDTPCEDVRIHSARHPVKTSGSTLPEDTPCEDVRIHSARRHPLIHSAEDTPCEDVRIHSAEDTPCEDVRIHSAEDTPVKTSRSTLPKTPPVKTSGSTLPKTPCEDVTIHSAEEPPVKTSGSTLPKTPCEDVRIHSARRPPVKTSGSTLHEEPPDPLCTKTPPVKTSRSTLHDTPCEDVTIHSARRHPCEDVTIHSARTHPCEDVRIHSAEDTPVKTSRSTLHEDTPCEDVRIHSAEEHPLIHSARRPPCEDVTIHSAEHTPCEDVRIHSARRHPCEDVRSTLHEDTPCEDVRIHSARRTPCEDVRIHSAEDTPVKTSGSTLHEDTPCEDVRIHSARRHPLIHSAEDTPCEDVRIHSAEDTPCEDVTIHSAEDTPVKTSGSTLPKTPPVKTSGSTLHEDTPVKTSGSTLPEDTPCEDTPPVKTSGSTLHEDTPCEDVRIHSAEDTPCEDVRIHSAEDTPCEDVRIHSAEDTPCEDVRSTLPKTPPVKTSGSTLHEDTPCEDVTIHSAEDTPYTPCEDVRSTLHEDTPCEDVTIHSARRHPCEDVRSTLPEDTPCEDVRIHSAEDTPVKTSGSTLHEDTPCEDVRSTLHEDTPVKTSGSTLPKTPLSTLHEDTPCEDVRIHSARDTPVKTSGSTLQETPCEDVRIHSAEDTPCEDVRIHSAEDTPCEDVRSTLPKTPLTPCEDVRSTLPEDTPCEDVRSTLPKTPPVKTSDPLCTKTPPVKTSRSTLHEDTPVKTSRSTLPKTPPVKTSRSTLHEDTPCEDVTIHSARRHPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHJ5</accession>
    <name>A0A3R7MHJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative rhodopsin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_024118</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000783">
        <property type="protein sequence ID" value="ROT82707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHJ5"/>
    <dbReference type="OrthoDB" id="2105199at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="8 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="522" mass="58230" checksum="8C87B2077939E9D3" modified="2019-04-10" version="1">MFSLWPPGCSIYGGGVGLLGLVSIVTLSWIAVERFIVIRTSSATSKWRITRFSQEIIIFIWIYCSALALPPFFGWSAYVPEGLMTSCSWDYITRTASNRAYYVYLLLGGFVIPVAAIICCYSYILVALFQHSQVLSGFRSCSLWALPVASGFESLSWRRMLYFLQEMRWSAPARRNDLRTAQMVLTLIMLFTISWSPYATVSLIGQFGDLSLLTPWVSTLPALFAKASVIYNPIVYGMSHPHFRSSLQHLFSSVTSTHQQMHHKPSTAARHVSVNSVLALPDESPRRHWHSDSAGIPAYYKAVNLRKASVTTATANGESYACLLAPDVTALANGDCPNLSEPDLLRHDDRVIPAHLVTYTAYHREKRRFLRSALFCSESSLERYDRRHQSQRYGRHTYVGGGGGLMPTTTPNCVLEQTGPDTWDHVALLEPSLPLRHDSGNLSVGSASPDPRRVSFSTVCSRSPRLSISKLNGARPHRHNNCCQCAASDLAQTVTVATMNNRRRSSTIHVCLRGNLHQFMDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJF8</accession>
    <name>A0A3R7MJF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative limbic system-associated membrane protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJF8"/>
    <dbReference type="OrthoDB" id="190835at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF41">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="158"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="265" mass="29504" checksum="B89FBF3024364F2E" modified="2019-04-10" version="1" fragment="single">MYLEVSQRYSPHTRQDPTQHTSKQQIRHWAHNKLYTTETHYTPGSHGVVILSSACLILCLRRAGFTLEQGIPHFNTKPYFLPPVATNVTALEGQSAYLHCRVASSGTRRVVGPLLDVRPDLRVSTKAFIEMQTGEMGGCEFSQARDSGAYQCQVNTDPRISMLFHLTVTEAATLMDGSNQRYVRAGSDIQLSCRTSVASQPPGLLYWYRDAEILNTGGRVDIATELENETKSRLLIKGARVSDSGNYTCWPTKFLPASVMVHVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK18</accession>
    <name>A0A3R7MK18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Squamous cell carcinoma antigen recognized by T-cells 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002514</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001336">
        <property type="protein sequence ID" value="ROT78776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK18"/>
    <dbReference type="STRING" id="6689.A0A3R7MK18"/>
    <dbReference type="OrthoDB" id="360390at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008669">
        <property type="entry name" value="LSM_interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF25">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05391">
        <property type="entry name" value="Lsm_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="683"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="506"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="747"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="594"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="647"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="790"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="805"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="821" mass="94115" checksum="1066166550615A0B" modified="2019-04-10" version="1">MKVEEIRKQLDGNELYYDGHVNLITVLRELMELEEARKAREKMSEVYPLTPELWLDWIRDEQKICSTPEEREYIINLFERAVKDYTSVQVWMEYVMFMLGGGDYTATRAVGEKALTAVGTHVAEGLLVWQVVLLVEKQRPGTVQSEEDMKAQEKQQKRIQGLYRRLIRVPLLNADYQHLMEEAAEFFEGDFDVHMKADLEKTKQKLNEKIPFEEKLLQAENDTNKLATYRLYIQHLQENDNPAAVQSLYERAVLDHCLDASLWEEYVKFVIRQFPGLDYLVLPICERSQRNCPWSAALCELHISALQLFHVGEETKTLMKKVKGALEKGLGSGLQSGSEATRMWMAYLVFQRRLIKWDQEHAAELDALRESGQQAITMIDSYFGESGDIESEIPRFFARIEAEFAKNMERAREIWNDIIMRRNNNFKNVSLWLEFINLERCYGTEKHCRKLFRRALERVWDWVESIGSAYLRFEQETGTIESMEEFQKRYEDRMFIVNKKRAEDAAKLGEGNENNQERRQQRDKGKRQDKKRQAFVQAKETENFKAPHPVSKYKQDTQNRKVGTSHEGSNGNDAPQSVESAVIPRPPGFKDIVTPPPGFKSDVPPPPGFKDTITPPPGFKDTVTPPPGFKGSSSPPPGYTGSSSKAGKREREDYTDTEPELKKLKVAELHGVRVKEDDSEDLCTVFLSNLDFSVGKEEVVPIFTNCGEVKDFRLVKDYKCRKTAEKVVKAMDGTEIEGKIISVMISDPSNKKKPNEGNVSTTSAVKNSEKKVPGSRGKGMFNLMPRSLMRATTSTAGPTSSEPETPVKPKSNEDFRKMFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK47</accession>
    <name>A0A3R7MK47_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C-type lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001326">
        <property type="protein sequence ID" value="ROT78839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK47"/>
    <dbReference type="OrthoDB" id="6344175at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="110"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="260"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="42324" checksum="3092A17A29AC4EA8" modified="2019-04-10" version="1">MDNNSIAPRCTHPALSEHRISIYLSSQVVQPFLVSDIPSMALWGSLPAREASSLLARCTCLASVTLCCLKKEYLASLRCLLLSNAYALSPLFSFSRFLLICECPQGFTHLGDGCYLFGQDPFVQSEAEDFCLGVGANLVSFDSCGAFGHVSRYLEMAGLATQGLGFWVGASRVDDKWTWSDSGDDLPYGAPLWDPFRTLEDAHACALLSATGGYLLSEECSQVALALCEVPVPPSAAGPSPAPKPERTPREACPEPFTAVGERCLYVNDNFLTWDAARASCQGLASGYVTDLAVLDTCDAFSLLARHLDGRNSAYQDWLWIGARDFEETGAFRWVSGEYVSPGVPLWCPGQPNAFEGRQHCAMLWGSNFYYVADDDCSDIRKSVCEVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK89</accession>
    <name>A0A3R7MK89_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative glutamate receptor 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_002329</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK89"/>
    <dbReference type="OrthoDB" id="6117597at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="11">
        <location>
            <begin position="169"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT78933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="35159" checksum="2E1BBF1C625D721E" modified="2019-04-10" version="1">MRIRTEAERKVFEKYFIGKESKKKWLLIFSDEFLRLLQPVHLPLDNQITIANFTIDGEGASLWESYQVSSYNAKRLLKVGHWRRARRCPDAHLDCLSFSNEVDEGLPSSDGSTPTSPRAAALLSIPKEVKTALLTMDSGVLLAPADDPVQRRKDLTGLHLTCTTIDYLPVIALEEGPVGSVRVGGLLGKFFLTLKEITNFTYTCRRVKDGEWGAAVDGHWTGMIGEVSDGTAEIAVAPLTVTQKRSAVTRFIPSADVVTKWLCFRPRHTALSLETSPIELKTVVTPFIQLGFSVLVALGILAAECFSRRSGIVSQGNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKT2</accession>
    <name>A0A3R7MKT2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_014327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01000280">
        <property type="protein sequence ID" value="ROT85431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKT2"/>
    <dbReference type="STRING" id="6689.A0A3R7MKT2"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="4">
        <location>
            <begin position="48"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="5">
        <location>
            <begin position="436"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT85431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="491" mass="52343" checksum="7AEEA1FFFF54A4AC" modified="2019-04-10" version="1">MAALRVTCSSSRLVTPLRGVLPSPCAGIATSSAMSGKDGVRKEQDTFGELEVPNSKYYGAQTVRSVMNFPIGGETERMPLPVIKAFGVLKKAAAEVNQEYGLDPKIADAISKAADEVISGDLYGEHFPLVIWQTGSGTQSNMNTNEVIANRAIELLGGELGSKSPVHPNDHVNKSQSSNDTYPTAMHIATAVEIHNTLLPGLEALHKALDAKAKEYADIVKIGRTHTQFSGYAQQIEFGIQRVKACLPRVYMLAAGGTAVGTGLNTRVGFAEKVAAKVSQLTGLPFETAPNKFEALAAHDAMVEVSGALNVIACSIMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAITMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMVANVLRSIRLLGDSCHAFVNNCVVGITANQERIDKLLHESLMLVTALNPHIGYDKAAKIAKTAHKEGSTLKATALKLGYLTEEEFDKWVRPEDMLGPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MUM5</accession>
    <name>A0A3R7MUM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Down syndrome cell adhesion molecule-like protein Dscam2 isoform X6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_011609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002464">
        <property type="protein sequence ID" value="ROT70131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MUM5"/>
    <dbReference type="STRING" id="6689.A0A3R7MUM5"/>
    <dbReference type="OrthoDB" id="5982258at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001049">
        <property type="entry name" value="Down syndrome cell adhesion molecule-like protein Dscam2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="63"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="272"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="371"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="51758" checksum="15C9BEA84ABBE706" modified="2019-04-10" version="1">MTYHFLIGGSNWSRPRGRHLGPRDPGRRRRVCRQPSPRTRPELSKATPQHTQDESCEGIREGPRLLQEPPPLLTFPNTRGAALTCAASATPTPTITWVTADGAHVDSVAGLRAVRGAHGNSTLTLHPFRPDQYRHDLHAATYRCLATNSVGTVTSRPVSVTAVVMQRYEVGVSDTAGEVGGPAVFTCDVPPTVSRHVTVTSWTVDGRTFRPSTRPDGRYWVLPSGELVVRGVTATDAYTHVSCTTSHAFDPAPHSSNAGRAIVTGDTMLSRPHLLLRRDLVRPWTREDFLLPCVARGYPPPTISWYHEDGTRGRVALGVGGSLAAGSGRARVVEGQLYLTGVTTEDSGHYLCVANNSAGTDSYRVNVQVRDRLSASVEPSLQRVDLGRPTRLTCRVSGTPVTSVTWYKDGRPIPPLPRITTYDRTLHIGQITREDGGMYQCLAKNDEDSTQAAAQVDLGEQLRAGTQVTGSAKGQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MY47</accession>
    <name>A0A3R7MY47_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transport and Golgi organization protein 1 isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002142">
        <property type="protein sequence ID" value="ROT72495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MY47"/>
    <dbReference type="STRING" id="6689.A0A3R7MY47"/>
    <dbReference type="OrthoDB" id="6372603at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035459">
        <property type="term" value="P:vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051500">
        <property type="entry name" value="cTAGE_MIA/OTOR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23158">
        <property type="entry name" value="MELANOMA INHIBITORY ACTIVITY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23158:SF33">
        <property type="entry name" value="TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="45"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="140"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="273"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="394"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="494" mass="55535" checksum="16D1D0F518941373" modified="2019-04-10" version="1">MSMATRIKGFGFSQVSKECLKQLRLTSDDDHATPDEEKLSAIFDVIRVKAELQKVTNERNDLQEQLEDAEIAQKNLEEAMASIRSEVAGLRDHHDLAVKEKEEALSKLAVLSQYFEEKEAQLTKELESQEGLRVDAEGSAAAVAKKIQNYELEIASYKTQLDSLRKELDDQEQSYKSQIASHEQKAHDNWVQARAAERKHEEQRLENNQLKSRLAMMQKEKEESQQQSMGIIKPTAKRVDANGSMSSPGPILDGMVDGNHSGPPSLHREVDSPPIPHPLHGPPPMLPLMFPPGAPIPPGVPPPHGLPPGVPPPPPGLPHGLPPPFLPGEPPFMGPLPPLPGGRLPPAGGMSSPPFRRSGSPSYEHRNDRYSPRSDRSHFSDGRYSPPMLRRRPHSPDSHRNRSPDRRSDRTRSPDMRSDRMRRSPDSRGDRRSPDRRSGRRSPDRRFTRSPDGYVRHRSPPRHFYDDPEYNDDPRLHSHLKGKKTSTPVGPNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N8A6</accession>
    <name>A0A3R7N8A6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_001303</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Stereocilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N8A6"/>
    <dbReference type="STRING" id="6689.A0A3R7N8A6"/>
    <dbReference type="OrthoDB" id="10261302at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032420">
        <property type="term" value="C:stereocilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007605">
        <property type="term" value="P:sensory perception of sound"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052420">
        <property type="entry name" value="Espin/Espin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153">
        <property type="entry name" value="ESPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24153:SF8">
        <property type="entry name" value="FORKED, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1009">Hearing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="3"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="212"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="265"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
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        <location>
            <begin position="449"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
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            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
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        <location>
            <begin position="514"/>
            <end position="527"/>
        </location>
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        <location>
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            <end position="559"/>
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        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT79964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="701" mass="76134" checksum="018935FFDA4C9957" modified="2019-04-10" version="1">MDNSVTPVYLAAQEGHLDVLQYLVESAGGRLDLRAKDGMAPLHAAAQMGCLNCLKWMITEQGVDINLRDGDGATPLHFAASRGHVETVRWLLKKGASVSLDKRETEGGREGRMEEGGGWRGFVPEPETSTGVKKVIKSDCFSFYFELHVLQLLVQHGTAPDYATDSDSTDSGSHHHHCTCHQSSRSKRKGSECSLTGSDSCTSSCESDCHSSGNSSDSGVHHEPFYLHPPTATESESKQKNQKNSFFLNPLTDLKEASDKYNKDKIEKAKSGDSSDEKSQEPFYLHKPEAATYQPNRVQELFGTKSVRNSVKQIESKNQSGKKTKSTENGSPGERRESGSSSGSVKENGNFSRNSIRRSEKKNGAFEYSSVNSDKKKGKVNYEDRKLPKIPSTSQAVTSSFKVKADVHSGDDSASVSSGDHDHHYEDIDPALVASRAAARESSGRARDPASASSPSRRSSSSSRTSPREGSSKEEREEEGSGEAARRKQRLQGLDDLIADPPQPPPRPPPPTFPALLPRTAPRLLLDTPPPHSHYPFFFHQPPPPPTIPSSSPSLLLTQPRPPPHPRPTPSPSYKGPAPRLLLDTPLHPLPTTLLLPPPPPTHPPYLLPPPPPSLLPPTPIATLLNGLACPLQESPHQTTTCEGRHCTTHQHDLTSVPVDMRPAYPATCIVLEPSAPHCALGTNCLQKRRVVSSLTSGTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NAS3</accession>
    <name>A0A3R7NAS3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000891">
        <property type="protein sequence ID" value="ROT82054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NAS3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="162" mass="17729" checksum="6F9D1819DF182949" modified="2019-04-10" version="1" fragment="single">RVISSSAGKLRKGRAPGEMERLTDKVRDTVATHMPSKGNSGGQKKKRRKKGGGGGGGGGGKDRSTDPSKHTRLPLSRAPHEPHDPSKKQENQPQARRRNGRWRRAGPPPRRSRSGRGGPTGATLRRLAPGPHARARPTRRMPTRHKPKTTTMVHRPSRARPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NEH5</accession>
    <name>A0A3R7NEH5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynactin subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_021402</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000449">
        <property type="protein sequence ID" value="ROT85060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NEH5"/>
    <dbReference type="STRING" id="6689.A0A3R7NEH5"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="16">
        <location>
            <begin position="27"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="76"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1026"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="200"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="903"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1173"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1031"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT85060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1267" mass="142227" checksum="9860B5E7F3194970" modified="2019-04-10" version="1">MSEKPIRVGQRVEVNGKDSLGTVAFVGSTHFSQGKWVGVILDEKKGKNNGSVQGKSYFQCDDGYGIFVRQSQLVPLDTEEEGEDGSAETTPSASSSATTPASDKPKSSLKRKVEPTSLKRKPTGNPVPQKPDRLRLPIGSAGKSAASRDERTPSKESSPRSDMKKTSSFVETNFVETLTPQYTPGAPSSAMQTLEDKMAAMQMQQEMENLRGEIRDLNEKLETLREQLLEFKSKIMESQAQLQREMQKAKQDAREAIESKDKHMEDTQELTENVEMLTLDKEMAEEKAETLQLELDQAKERIEELTLDLEILKTEMSGGGGATPTDGDSEATSFKVRQLEQQNSRLRETLVKMRDLAAHDKHELQKLQKDMETKKTEVTELNRSRVKLTSQVAELEQTISDLQEQVDAALGAEEMVETLTDRNLNLEEKVAELHETVADLEAINDMNDQLQENARELELELREELDMANGKIREVMREREASNEIIVDQESTIKKFRELVQKQQEQNIELRQALEKETNKPIATPSEIIDFKKMFIETKAHSKAIDMELRQLEVAQANQHVAYLTQYMPDNFMTRGGDHDAVLVLLLVARMVWKAEIVIGGLRDKYPAPDTIDRNTVLKSHSVEQYAFASRLLQLLYALQALLHQYEQVLNTCNVEVFLKLGTLYGEMASHERNIDFYVDLLRKDQLDENTPMDALEKTVGYFSTVYPAHLAAEKINQSLYLTDVARVLSSGTDAASTYSSAILTMLHPQHESSDVALVCRDIVNASKDIQGAVKRIRRRMPQDGSVGPLSYPQDVQEALTSAIANMNNSTRALRHVSKACQQQTSLLADNENGILGEKLKEFIHQATDLIYGREDLGPESLRLSLSRTQNDINRVANTLEKGEYDFDGSVEERTVQPVVLRAQALKDEMKDTEHIKYKLENKEQDLKDLKLTLKQKNEELSEMTVRRDLAEKKLSTATRDSDLTIEKLQRKLDDTLMMLRRKEKEYDETMDHLQSDIESLETEKGELREKLKALNKKTLYEALSKSSPLTGVSPSSPTTPSAAGGAPTVGGGVVRDSPMLLQQINDLRTALNHATAAAHYNTAHRMHRQLAALKPIKIHHLGSGEEKRDKTKEEAFEGEKKSIDHINQLTRQASHIQKEVHNMITGVEVVDLSKRRAGTLPCTDLASPAHHLINYNNRINNLRSQITLLQDEITKAVATMKPGGSVETALSTFPSPQLTKAMGEQDLVCVGRLKVPASTSTETSKEPVPVILQPNHLKKLHLQLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRE1</accession>
    <name>A0A3R7NRE1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein OS-9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_017397</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Lectin component of the HRD1 complex, which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). Specifically recognizes and binds improperly folded glycoproteins as well as hyperglycosylated proteins, retain them in the ER, and transfers them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 as well as hyperglycosylated HSP90B1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the HRD1 complex, which comprises at least SYNV1/HRD1, DERL1/2, FAM8A1, HERPUD1/HERP, OS9, SEL1L and UBE2J1. FAM8A1 is stabilized by interaction with SYNV1, which prevents its proteasomal degradation. OS9 and UBE2J1 recruitment to the complex may be mediated by SEL1L. Through this complex, may interact with ERLEC1 and HSPA5. Interacts (via C-terminus) with CPNE6 (via second C2 domain); this interaction occurs in a calcium-dependent manner in vitro. Interacts with CREB3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OS-9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003214">
        <property type="protein sequence ID" value="ROT64655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRE1"/>
    <dbReference type="STRING" id="6689.A0A3R7NRE1"/>
    <dbReference type="OrthoDB" id="239053at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.130.10:FF:000002">
        <property type="entry name" value="protein OS-9 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF5">
        <property type="entry name" value="PROTEIN OS-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018539161" description="Protein OS-9" evidence="12">
        <location>
            <begin position="19"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="13">
        <location>
            <begin position="100"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT64655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="416" mass="47267" checksum="84433F528CDAEC62" modified="2019-04-10" version="1">MIFHILVVVGTLLATGNTLNTVLNVEEITSIHYAVDIIEQPVSREQHLEGEVISVVNKHGQEFVCSLPSVTPTDADSKSDENILDQLVDISGLLKPMETAPCLIKTVDWWTYEFCYGSVIKQYHLEDNKASGPILILGKYESEYNWKNSSETKNRLQRFHSQFYVNGTKCDLTGEPRRTEVRFHCEDGVGDYIQRVDEPESCRYVVTVATTRVCHHPYLRLQAVRTPHAVTCAPVISEEQYLRYVDYQERKTKEEENLKEKWLKQNEERTHESEMGESQSVLEPVKSDTADDDELKMSIKIFRLYPVKKQKNAQASEAKEDVMGVETQITLEENDLEMKVEDINLSTETEASGNGQINGEYGTDIDKNTDIPETTGEAETKDLFSGQDNLHIVQYSNTAAAARLSSFSSFFFSVHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NSE2</accession>
    <name>A0A3R7NSE2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Matrix-remodeling-associated protein 7 helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NSE2"/>
    <dbReference type="OrthoDB" id="5983600at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026622">
        <property type="entry name" value="Mxra7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057534">
        <property type="entry name" value="MXRA7_helical"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21845:SF2">
        <property type="entry name" value="MATRIX-REMODELING-ASSOCIATED PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21845">
        <property type="entry name" value="TRANSMEMBRANE ANCHOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25473">
        <property type="entry name" value="MXRA7_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Matrix-remodeling-associated protein 7 helical" evidence="3">
        <location>
            <begin position="87"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="17288" checksum="4378E96669DAD214" modified="2019-04-10" version="1">MHHHPPSPYTTSPQTPHTTHPFPHHPITEAARSSCTAIIIVSWILPFNSSIRNRKTKIKIKIDEPEDDEQELQRLLDMAHHAPGDVKKAQRRALERNIETHMSDEQRQAEREAQSQQLAAIFKMMKEQEEKFGETTIDEIKDQMKLYCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7A4</accession>
    <name>A0A3R7P7A4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003524">
        <property type="protein sequence ID" value="ROT62930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7A4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="39361" checksum="B582B413DEA0A1CE" modified="2019-04-10" version="1">MLSGLLLGSAFILSCVCPVLCLSASALVPSLLSSSSLPPLLALSLLSLSLSVSFVSSPLVSPSLSLSLSLSLLSSLVSSLALSLLARPLSLHLSLSACSLSSRSPLSSSSLPALFRSSLPALTPSSAYPSLRSFPAPRLLPLLPLFPLPSRPSPSFSPLPLSPSRPSSSPSQIPLPSVPLSLSFSLSPPVLSLVSVSLSLLIVVSCVSSLSLSSPLLLLSHSSRSLSRLSPLSSSLSLLSPLLSEGFVVAMGVSRRILYRISLSLSLPLSLLSLPSPSLSSSLLSPLPLSLSLSRLCSLLLSSHSSSPLSLSLSSYLSLRPRPAVLSCAETFSLFRGNSRARDGNHAPLISPPVTLIRCGYADMPRCPNTQNGLWWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P8Q8</accession>
    <name>A0A3R7P8Q8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA-directed DNA polymerase from mobile element jockey-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003346">
        <property type="protein sequence ID" value="ROT63998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P8Q8"/>
    <dbReference type="STRING" id="6689.A0A3R7P8Q8"/>
    <dbReference type="OrthoDB" id="418748at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47027:SF28">
        <property type="entry name" value="ENDONUCLEASE-REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47027">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="35"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="54063" checksum="5BDF8C0D0FEF5826" modified="2019-04-10" version="1">MKMKNGKAVGPDNLPVEVWKSLGIIGIEYLKQELNKIMEEKIPDEWRKSTLIPIFKNKGDIMECGNYRGIKLMSHSMKLYERVQESRLRNIVEISEEQFGFMKGKSTTDAIFVLRQLQEKFREGQQELHSVFIDLEKAYDRVPREELYWCMRDKGVPEKYIRVVKDMYECCVTEVKCAVGTTQSFPIQVGLHQGSALSPFLFAIIMDSLTKDCRRKAPWNMMFADDVVLCAREKRELEEDLEQWRYALERRGMKISRSKTEYMCLNGTSTGSVEMLQRQLPETMAFKYLGSTLETDGGVGAEVNRRIQCGWNNWKMSGILCDKSIPSKVKGRIHMLVIQPAMLFGMETVPLSTRNTKRLEVAEMKMCRWACGHTLKDHVRNEVIREKLGITHITEQFRKARLRWFGHVKRRDEEYAGRRVLEMAPPARRRKGRPKLRWMDCLRKDLEELEATEEDALTGKPGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAA3</accession>
    <name>A0A3R7PAA3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDP-glycosyltransferases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_001311</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAA3"/>
    <dbReference type="STRING" id="6689.A0A3R7PAA3"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000050">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018793261" description="UDP-glycosyltransferases domain-containing protein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="968"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1013" mass="114275" checksum="A8B331B574F09DA9" modified="2019-04-10" version="1">MMKWAVLTLALMGVAWAELAPPERSYKILMLLPVSSKSHRNVFLPVAEGLADRGHKIVILANHPPALNHPNVEEINHGLSEFNTEAMDLFAMRPDPAVVFKVLQDALPIIARKLYKIPKVKELYDRRKEFDLLVINHMFNEVVYPFAHEMPFITVATPGMDSRQSAVFGNVLNPAYAPTFMNAFPLPMSMIQRFLNTIAHIRIAATWRYFDVLPSVQKEISSQFPDLPPLLDIERNQSLALLNSHFTVTGVLPLLPSQVEVGAMHCRPGKPLPEDLESWISGAGSEGVVYFSLGSMAQGQSMPKKYRDMFVEAFKQLKQRVIWKYEVALEGVSDNVLMRKWLPQQDILAHPNVRVFITHGGLLSTLESFYHTTPVLAVPIYADQPKNGMNIQASGLGLMLVWEELTVELIVNSLKELLNNPKYRATAEEVRSALRDQPQSPKDRAVFWTEYVIRHKGAPRLRSPAATLSWSAVEMHWADPSSPLCLQSPRSSYCTNKMRVALMVLLVALAGVSLGKLAPLEKPYKILMLLPAGSKSHKVFFMSVADALAERGHKVVMLSGYPASSKNPNVLEINHGLKEFDVKNMNLFDFRNDPTGGFSILVDILPAMAKKLYKIPQVMDLYHKRKTFDLIIVDQLMNEMIYPFVHERTYMTIAAFGMDACHSAVLGNVQNPAYVSGMLEEYPSPLGLKHRFLNLMQHILMPFYLRHWSLVPKIQKEISDIFPDLPPLLDIERNQSLTLINSHFSMEVAVPLLPSQVEVGAIHCRPAKPLPKDLESWISGAGPEGVVYFSLGTVARGTTMPVVYRDMFVEAFKRLKQRVIWKFEEKLEGVSDNVLIQKWLPQQDILGHPNVKVFITHGGLLSTQESLYHATPVVALPIFADQPKNAMAIQKHGLGVVLVWEELSVDLIVNSIQEVMNNPKYKRNAEEVMSVVRDQPETPRERAVFWTEYVVRHQGAPRLRSPAAKLSWVEFLMLDVLLVLHVVVYVAFCVLSRVVRAVKGKLFPGKAKKRKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCF0</accession>
    <name>A0A3R7PCF0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_025061</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000917">
        <property type="protein sequence ID" value="ROT81778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCF0"/>
    <dbReference type="STRING" id="6689.A0A3R7PCF0"/>
    <dbReference type="OrthoDB" id="3176202at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000322">
        <property type="entry name" value="GDNF-inducible zinc finger protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="330"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="395"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT81778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="48364" checksum="746CA9BEB7753D2F" modified="2019-04-10" version="1">MSHLNSHVTIHSQEKPYQCSICSARFRRKDCLGRHLNTVHYNREYLQEPSPRDESGDVAEQSAFFQNFASFFTPSEDWKEALPLTVEINAGDFPVCLDTDNNSDAGEGVTETQDEEPDPPKDQREAAKLSVSQMGFYECEVCYQIFARECGLRTHMEVHSEIRPFACPHCKERFPHEASLIEHCRMHIDPAKNVMKPQKSPSDQEHPDTISAELRRFHKLAAETVASSEKLSRCAVIANKNIELSADNSKYVGPAEGVEGSQNEGTDLTGEVKNLLSQRRPYECQTCHASFKMKHHLKCHMVVHSDIKLFQCPQCSKAFSWNHTLKRHIKVHTKSPKKPRKSPSAQRPEKTIKQEEPRLAPDEEPDSTLPILTLQDAAADGFKICEDDLLMNKALEVKEEPNEDTGDSPINVKSAERDSLNGNVSRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCH1</accession>
    <name>A0A3R7PCH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000911">
        <property type="protein sequence ID" value="ROT81845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCH1"/>
    <dbReference type="STRING" id="6689.A0A3R7PCH1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="483" mass="51709" checksum="E5248DB904EC4EE5" modified="2019-04-10" version="1">MASPPVLPTLPPWPPVAESPGDQLFLLSPVSVLSCLSLSLSSFSFFFIFHLSSFSSFSFPSFFIFSLFFFSSHLSLPSFPSPPVSSFRTPSSRLLPILPSPNPAIFPSATSPPSAYISPLSPSVSHSLPHTSNSFSHSFLAPSPLSPHSFPSLSPLLPLCLIPPSPLSPHSFPSLSLCLITPSLSLPTPSLSPPQLLLCLPFPALLSPTPPPLSPHSSPLSPFLPFSPHTSPSVCFPLCLPTPYPLSPHNPPLSPHTFPSLSPLFPLYPPPSPPPLPFLSATNTCTGFSGSLFLSSFRPTRISEDVKNDLEMEEVEKPLLLLCFLFFSISSTCHLRFLLHSLSSSTTSTRPVHLSQSLHVPHPPPSPSPLSLHTKHKTTVNTTSLAHDIPSPLPYSSGPPPNFSPYPLPCLALVPQPCLDLAPQPCLAFPYSPSLPPSPPPFPLALLPFPLALLPSPSPPPFPLIPLPSPNFPPFPPSPLPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDU3</accession>
    <name>A0A3R7PDU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000742">
        <property type="protein sequence ID" value="ROT83075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDU3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="650" mass="68895" checksum="DC2725011896966C" modified="2019-04-10" version="1">MVTLQGSSPLPLVLWRSASPQPPSSSSPASPALPSVAMVTTHAINNTSDQQISPSSLRVAASTPSPQPLQHSSPSPPPSASPPPGPSGLCWSARGGGEVALTPDHRGNLWAVTTSSLGSHVAPGRVWVLNFTSLTWHHLEAPRTDARDAAAPPESSREGADPPLARAASTPPAAPAPPEDATPKGVPVASESAPLALCSWSKGIIVLYALNGSATTWMFSVKTGKWLETTHSKFPPAAAALEASWCGARHDAIWFLTSKRQKAAGPARSSSASVQGTSQTLWKLDHLGKWSRLEVTQAKGESHLESPATVLQSWTDARGNLFLLQEHEAPESKVSVVRFDPSSGEKTLTGLKGGARDGAWIPGSSGELYALFPRDGASWVATYDYYSGDVISTEKAAMPMASESLFVKVDGVIHTTIPACRHLPPMPPHLQEPSPPDMRFSHISLSRVCAPGEMDFPAGRPSQGVIQGPRKADVLSNVQAPPKNRYVSDTRAAAPAQSSSNHLDVEGTRDGAATTTLQDHGGEPGVSRTTGKSADIIMVRDDQEMRTWPVGPHQMNRSHTHDSIIFFSLSLSIFALVGIVVFVRRCVRCPPSRGLGDAPEDRGKPPSPLPVLYSIVPDDPAYETSATESPCISHHALYDSSPYADLPNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF47</accession>
    <name>A0A3R7PF47_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000505">
        <property type="protein sequence ID" value="ROT84743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF47"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="497" mass="52484" checksum="BA3AA429A16DDE3A" modified="2019-04-10" version="1">MSDITDGGKVPLPPPHNILLLPPQYPSHTPQHPSPPLPYNTLQPSPSHFHCPVSLPALVLSPSLLLPSPRLSPSPSPPRPSFSPRLSPLSLSPRPPLLSPSPLSLSLPPPLPSLLLPRPLSSPRLSLSPSPSLSLALSPSLPRPLSLALSPFSPLLSPSPLALSPSLPRPLSFSPSPLSPSPSLPRPLSLLPLALSPSPPLLSPSPLSFSPLSLSPSPLPLLLALSPCPSLSPLSPLPSPSLLLPLALSLFPSLSSLLLTSLLALSPSVYATPPLTAYRPIRTLRGSLIRSSLSSLSSPFPCSSRLPLPSPPLPLSSFSFFSSLLLPPFTLSTRLPPSSSSSLLPSSSPHPLRHFPSFFPSFLSPFLLPSIPALHSSPPSSLFPLTSLLLFFFYPLPNLTLTPSFLLPPVLRHFPLFPPSSRTPQAFPSSFLPSSLSALLSLSFPLPFSFLSLPHSFSNLSLLPSSSSTPTNPHPPPHMAVTGGQSAKLPLIILCFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF72</accession>
    <name>A0A3R7PF72_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RWD domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012186</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002546">
        <property type="protein sequence ID" value="ROT69598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF72"/>
    <dbReference type="OrthoDB" id="167315at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902073">
        <property type="term" value="P:positive regulation of hypoxia-inducible factor-1alpha signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033235">
        <property type="term" value="P:positive regulation of protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23819">
        <property type="entry name" value="RWD_RWDD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd24164">
        <property type="entry name" value="RWDD3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038840">
        <property type="entry name" value="RWDD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15628">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15628:SF1">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="6">
        <location>
            <begin position="6"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="254" mass="29081" checksum="5820CC2047B92311" modified="2019-04-10" version="1">MDDILEEMQAIEAIYCGEKEFELLSQGELSVMFSVTTSPTHHPDLRISLMFTLSVESYPEEVPPFSVQCTSLSRQECEDLKKSLKEEAELLRGSPMVLNILTALQDKQLKVAQTIIADSARPSINDAKVYVLQLDHMRNKTRYVKTIQRWCRDLSIVGGLVFYSRWIFLILQGDEESIKTYIQRNKTQVVDVDSSGRPCKERLLSVLHIGDHPVMLTEFSTCDFKNITDLKEWMMDAKLVDIYESVIAPVVIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGD1</accession>
    <name>A0A3R7PGD1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016368</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003060">
        <property type="protein sequence ID" value="ROT65665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGD1"/>
    <dbReference type="STRING" id="6689.A0A3R7PGD1"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="31"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="105" mass="11348" checksum="9B626F70E75BF2A2" modified="2019-04-10" version="1">MLRLGAQQLLRYGGGRSMVLGGARTQSSAPEKIEVFIDDKPVMVEPGTTVLQAAAVAGVEIPRFCYHERLSVAGNCRMCLVEVEKSVKPVAACAMPDEGWAQDRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSQ3</accession>
    <name>A0A3R7PSQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ca-activated cl channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000968">
        <property type="protein sequence ID" value="ROT81465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSQ3"/>
    <dbReference type="STRING" id="6689.A0A3R7PSQ3"/>
    <dbReference type="OrthoDB" id="6366627at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="1">
        <location>
            <begin position="37"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="28203" checksum="7F63A96FC8D86FCC" modified="2019-04-10" version="1">MAPNCETCHNQLSTNEYLARLYSFSVANPASLSPQTVLTSWSTGLYTATDGGLSLRSAMVLLPSHWSTRACHPPVSGRPPAPPTQPAHMLISPPHPVFADAPWTQQSGGCGRQGDFIQMGVGFLESANTSSAHAVRAASQLVGEWGKYRWGLFSEAGYAGDNLYLPWYRQGPDWAATVCTDAHAGPPPCHPDHAHHCSWPPEAHRNATSSLLSLPNLPQVTKFCDSKTHNREAPTKQNVLCGRRSAWEVMLEHPDFKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSQ9</accession>
    <name>A0A3R7PSQ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-glucuronosyltransferase 2C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005539</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001716">
        <property type="protein sequence ID" value="ROT75894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSQ9"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="241" mass="26984" checksum="A38BBE93BA0A91E0" modified="2019-04-10" version="1">MELPPPDIPNVTEVSTGSRAVQQVNMFEGSRTPLRVYRWAMRVSEVIGRAMWTNEEVKALWQRRRDFDAIVVIGYANEVAYPFLLDFEGLHVSLCTPGVEYLQVAQLGNRLPLSVVPAIFLPFDENMSFLERLVNPLAQLLTHYLYKFMVLPTAQRVVEEFFPGIPPLEDLSQGSQLTLINGHFALDTPVPLLPNQVEIGTINAREPQPLPERPPQQVISSSTVLPPNHPLSSNTLGTLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUA1</accession>
    <name>A0A3R7PUA1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">alpha-amylase</fullName>
            <ecNumber evidence="6">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_004123</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01001548">
        <property type="protein sequence ID" value="ROT77237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUA1"/>
    <dbReference type="STRING" id="6689.A0A3R7PUA1"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000020">
        <property type="entry name" value="Pancreatic alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12" id="KW-0868">Chloride</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alpha-amylase C-terminal" evidence="15">
        <location>
            <begin position="122"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT77237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="212" mass="23824" checksum="CE2530101D98652C" modified="2019-04-10" version="1">MHRANSLVFIDNHDNQRGHGAGGDMILTFRVPKWYKMANAFMLGWPYGYTRVMSSYYWDQWWENGQDKNDWVGPPHDDSFNIISPSFNADGSCGNGWICEHRWRQIYNMVEFRNVAHGTDMNDWWDNGSNQIAFCRGNKGFLAINNDGWDLKETLQSTCLPAGTYCDVISGSKDGGSCTGKSVTVGGDGKAYIEITTMEDDGVLAIHANSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PW83</accession>
    <name>A0A3R7PW83_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022248</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000528">
        <property type="protein sequence ID" value="ROT84556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PW83"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="558" mass="60278" checksum="7C8B816C17E9FB83" modified="2019-04-10" version="1">MFDEGSETTPAPQEKTKGDEWGKNSQAATGAVTYHARGRASSCIFQCTFCCRVPVSWSQPSRLRESSCGRVAHPGCATASAASPRPTCAHPPLPACAHPPMSRARAGKGARPRAPRGGPPPARGPLPALVRDLVAHRAVGHAPLLPAQELLPLVDRLVEFRVLRRLGLGCDLVRHRSFRSLDVLEVQRLIPAGGLPLRADEIALVLSILVSGLVRPVPFGKPRLLHEGVLRGPRAPAVAPDGRELQDRETRPQERPRPTAPSCPHVYTLAQRHTSRAACQDEAVRRTAHRCQRGDTHASAVRPALPPRADTILRKLPCTFKRRRPGATRRLSRAIKVSSLAGRRRLARTEARRTTADKGARLTPLHFTATCHSSLPEDPRKVHARELLLCPDAPAVPERPPLRGITPGPASQSHSPNPPTQRSATPPPPLLLKAITSSILPSPPLPSRPPFPASRPSLPLPLPPLPPRPPHLAPSCPLPFLCPPSLALLPPPFPLPSCPALDPGASLALLSFSSLWSYECFLIIFLHFLFFLFSPSLASPPPSFPLSDFPFLSFSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2K8</accession>
    <name>A0A3R7Q2K8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="7">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_015067</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family. USP14/UBP6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01002879">
        <property type="protein sequence ID" value="ROT66875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2K8"/>
    <dbReference type="STRING" id="6689.A0A3R7Q2K8"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02657">
        <property type="entry name" value="Peptidase_C19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000119">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000032">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="9">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="10">
        <location>
            <begin position="106"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="377"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT66875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="507" mass="57781" checksum="28EDBE1B7D06A963" modified="2019-04-10" version="1">MTVFSVNVKWGKEMYPGIELDTAEPPMVFKAQLFALTGVQPHRQKIMLKGATIKDETWNGVKLKDGATVLMMGSKEEDVPVEPTEKTAFVEDMTEAERNTALELPVGIKNLGNTCYLNAVIQCLKTVPELHSSVTEFKPKPPGREGESSSNLLTLAVDSGSLLTLAIQECYRTMDSGKTAVPLVLVNLFRTTFPRFAEQGEQGMYMQQDASECWNELTRLLMQEVPSKDAEKTDKKFASSLIDQYFSGEYSCEWKCIESEEEGVTHNTDKFQQLMCHINQDVKYLHTGLMAKMEEHIDKRSPVLDRDAKYVKKSKISRLPAYLTVVMVRFFYKEKGAVNAKILKDVKFPINLDVYELCTPELQKKLQPIREKYKDMDDRKLEEDKAKRRGKPISEDKKPKTKKLPYSFEDDLGSNNSGYYQLQAVLTHQGRSSSSGHYVSWVRWRGDDWLKCDDDEVTPVTEEEILRLSGGGDWHCAYILLYGPRVLEVLDEDEKQPAAEEVKMETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9W0</accession>
    <name>A0A3R7Q9W0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004337">
        <property type="protein sequence ID" value="ROT61129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9W0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="527" mass="56517" checksum="B6548C3443BADE40" modified="2019-04-10" version="1">MYIFSFCFYFLSGFIFFVYIFEFFYFFSIISFSLSCCLICFRYCTFLPTSSFTSFPFLSLTPFPSSFLLSFLLLYLLTLPTYSSYPSSPPHPIPFPSTPPFPSISTTFLPSLLSIVLFSPSFPPFVPYSFPPLLPLTLRFFNSYPVLPLPPPLPPTSTSTLPTPPFPPSLPPPPPPPLPTPLSASPPSSPSFLTFSSAAQHPYPHPHSLPSSLSLSSASPPLPPLSYPFPSLPPNLTSSPPPSSLSLSALPSSPSFLTLFLLPPNTLPHTPSIPPPSPLSLSASPLPLSLPFLPFSFCRPTTLPHTPSIPLPLLSLSLLSPPPSPSAYPTTPSIPLPSLSSLPFPSFLTLFLLPPNNLTPHPLHPPPPLSLSASPPPSSPSFLTLFLLPPNNLTPPPSIPSPSSLSLSPPLPPPPPLLPFLPFSFCRQHLTPHPLHPPPPPSLSLSASPPPSPSFLTLFLLPPNTLPHTPPSPSLPSLSLSASPPPSSPSFLTLSFCRPTPYPTPPPSPPPPLSLSLLSPPNRIAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QA38</accession>
    <name>A0A3R7QA38_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative neuronal acetylcholine receptor subunit alpha-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002137">
        <property type="protein sequence ID" value="ROT72553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QA38"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="45141" checksum="2280DCE832A27C2F" modified="2019-04-10" version="1" fragment="single">QAYDLNQVRRLHHDLFNNYNMHVVPSSQTIVKFRMNIKHFDMIEDTQALMVDSWIVNEWVDPRLKWDPEDYGRVYKISVPHTMLWKPDLDVYNNANVGKPLSYGNTLLIVFHDGRNYPPPLSLPNYSFSLSQTYSPLSLLKLFPPSLSPNLFPFLSLPELSPFSLSPKKLIPLSLSQTYSPFSLSPKIIPPSLSQNYPPSLSPPLSLPKLSPLSLSQTYSPFSLQNYSSSLSPKIIPPSLSPNLFPFLSLPELFPLSLSLSNLSPFSLSPKIIPLLSLSQTYSPFSLSPKLIPLSLSLPNLFPFLSLSPNYSPFSPNYSPFSLSLPNYSLSLSPNLFPLSLSQNYSSLALSKSSPPSLSQNYSHFSLSPNLFPFSLSLHSSTSTNCKQLMGRTSPVACGTFSTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBU9</accession>
    <name>A0A3R7QBU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003551">
        <property type="protein sequence ID" value="ROT62791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBU9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="641" mass="70699" checksum="91374F98EDE600BD" modified="2019-04-10" version="1">MTVYKRRCNSPQTMPRWSAHTAAVVRNPDDRPTGTPKTMGNFRDWFADRILSSPSHPALCSTLRPALCSTLRASFLLPSQTCSKFTLWREHTRKLCAFVSYHHSLNAGAQAQALHGLRGALWHRTTLPERSQTTTLCGPYLHADRTTRILRGRREKLKPTLRSNTETTPNSCEGQASAARFPPAPASKNQQGERGEKERKKRETRGQAACVALCQLNIDQVPRSHAPYSLKPHLLSLPFRSSTVAFSAQTSSFNERPSLASWRRSGGGFPKTPNSPGARLLQGHPRQASTSAKEAAPEDQTEISKHVSPRTPTSALPVQGCSPRVHAPTSAPPGPWHPRRRLANGTWRRGSALGVGVQEFREAWHAAMRRAVADSIRFRSVPVRSPASPTPRQRRRGRNYKLADQIFLPAGLLRQPHGRSTDAEMLPGPILRGPWTRPECQTEMAQSWHSVCPSAASSCPSKRARDLPWQSVRPACPAEVESIAQEHATRNNTRIVARKSRAHHFATPDQTRPKWRTSLASCAAAASLLRGYSRLSREGRRRGTARTHLCRGTVAPSLVIKAVRSWRRPCGAQAGSRGSGAGGHVSPASRTRHCVTRPPDTASSDKLITFSKKLFPESRATLPALPRSDPELPRARATDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGW1</accession>
    <name>A0A3R7QGW1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transformer-2c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014972</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002871">
        <property type="protein sequence ID" value="ROT66972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGW1"/>
    <dbReference type="STRING" id="6689.A0A3R7QGW1"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12363">
        <property type="entry name" value="RRM_TRA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="102"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT66972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="22771" checksum="B5AB8F569B29E83A" modified="2019-04-10" version="1">MSRSPQHAVANGASPVRERSRDPSFSRSRSRSRDRRETYKHSSRSSGSPRYREERYREDKYSSSRRRDSRSPSYSRNRRSNRSPMSNRRRHHGSREDPSPSNCLGIFGLSLYTTERQLHHLFGKYGHINEVQVVLDAKTGRSRGFAFIYFDHVDDATEAKDQCTGMEIDGRRIRVDYSITERAHTPTPGIYMGRPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHC4</accession>
    <name>A0A3R7QHC4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Catalase</fullName>
            <ecNumber evidence="11">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_002403</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01001316">
        <property type="protein sequence ID" value="ROT78899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHC4"/>
    <dbReference type="STRING" id="6689.A0A3R7QHC4"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 11" id="KW-0349">Heme</keyword>
    <keyword evidence="7 11" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 10 11" id="KW-0408">Iron</keyword>
    <keyword evidence="4 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 11" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="13">
        <location>
            <begin position="24"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT78899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="520" mass="58849" checksum="37579AA362220423" modified="2019-04-10" version="1">MPRDKCAEQLNDFKKQQTAPDNLTTSHGCPLADKLNSLTVGPRGPILLQDIQLLDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDISKYCKAALFSEIGKRTPIAVRYSTVGGESGSADTARDPRGFAVKFYTEEGNWDLVGNNTPIFFIRDPILFPSFIHTQKRNPATHLKDCDMFWDFISLRPETTHQVSFLFSDRGTPDGYRHMNGYGSHTFKLVNEKGEAVYCKFHYKTDQGIKCLSSKKADELAGSDPDYATRDLYNAISSGDYPSYTMYIQVMTFEEAEKWKFNPFDLTKVWPHGEFPLIPVGRLTFDRNPKNYFAEVEQIAFSPANMVPGIEASPDKMLQGRLFSYNDTHRHRLGANYTQIPVNCPYRARTRNYQRDGPMCVDGNQESAPNYFPNSFSGPQDCRKHTAPKFSVSADVDRYNSADEDNFTQVGIFYRQVLNEAERQRLVENIAGHMVGAQEFIQDRAIKNFTQADPEYGANIRRAIDKIKMSQASSKTQHIHALAASSNGAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMP7</accession>
    <name>A0A3R7QMP7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">V(D)J recombination-activating protein 1</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_022783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="2">Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RAG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01000608">
        <property type="protein sequence ID" value="ROT84031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMP7"/>
    <dbReference type="STRING" id="6689.A0A3R7QMP7"/>
    <dbReference type="OrthoDB" id="10038928at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097519">
        <property type="term" value="C:DNA recombinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905347">
        <property type="term" value="C:endodeoxyribonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990238">
        <property type="term" value="F:double-stranded DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002250">
        <property type="term" value="P:adaptive immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033151">
        <property type="term" value="P:V(D)J recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024627">
        <property type="entry name" value="RAG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058552">
        <property type="entry name" value="RAG1_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058553">
        <property type="entry name" value="RAG1_pre-RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058554">
        <property type="entry name" value="RAG1_RNase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023336">
        <property type="entry name" value="RAG_nonamer-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11539:SF0">
        <property type="entry name" value="V(D)J RECOMBINATION-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11539">
        <property type="entry name" value="VDJ RECOMBINATION ACTIVATING PROTEIN 1 RAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12940">
        <property type="entry name" value="RAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26024">
        <property type="entry name" value="RAG1_DNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26025">
        <property type="entry name" value="RAG1_pre-RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26100">
        <property type="entry name" value="RAG1_RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="1 2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="753"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="945"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1021"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1089"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="945"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="959"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1089"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1143" mass="128275" checksum="1402F8C40ACFD37A" modified="2019-04-10" version="1">MDAGDGDTHAGDGEETRHLNKAEQYTDADKEQSSSTVINADKERDSDTVTAEGEQGKPCDAGSMREDSEQVNSKIVHGIPSDGEVVKEEPMSPEHQKGDTRDAEESGTEKQTVKINENEEIERREDAANKEHELPVQQEGTEEASDQAQELVGDDEASEDTHMYKLGKICRICAEMTVVFDGPKKGVPKHEIVKHVRKVWNVDLSDEDPDIYPVNVCQYCERKIKRLYLKVSKKKKCEFYRDKPADFVAHTAQNCSVCLLKDDQPDSPCNPAAEEAQQVGTVEARVGSQGEGSQANKIILPSTEPRRNPARKRGWTDHEAETPQFVSVGCQTEEDGTSENMTGLEEHDYTQDEALSQFLVIPKKFGGRTPYHKLSLTAVNAKYIRQDRLKPLIAHIDKFCQVQKENKIDAMFFLLMEALRDAGDRVRETQVEDIWCRKNNVGMSLTDEECLAKRILLKQTKDQYRKEYSYYKEKLEKAVLKPPFIIDKLEKTYFPEYLEFFVTEGETGPIIYQHEKRSHPSYFAISGSAESNSKLDSNYAGVVGARWHYFDAVAKTLEELAHSLENEIHELDDDSCIQVDLLDYCEEKRDLTNFGDKNDSAATGRCSQSKMMTYFFGIQTMQAIIDNKIHYIYKSNPNNVQFRPLMKALVAEGNTLRPTIRSIEEERATMSEKVFYITLPGGTPLRFMVYFANATLEIRKDYRNISGLTLSSFKKVPAVINRYGNICLELKRSWLATSPRLIHVGRVTNCRTKCSRCGEQGHNVRKCTVKSENVSGDSVIHHRKRKKQRSVPAHSYPVALTQNTYSQVYVKDSKIVDLCNPHPHPQQPQQHQEPEEQDPLSQLTTVANPMDQGNAVIRSDEQILWTCPSIGGGSQPLSGTALPATQVLVPSSVSTNAEYQTGSHRSQAQASQGTSGPVYVWTYTVVQPQHGSSQQPAQQLSLIPQQNPQQGVTQQSQQLSVIHPQSGQQGTSQEQITVVHQQPVHQGAAQQIAVVHQPAGQQAANQQTQQLSVIHPQTSQHAPVHPSHVVPHQQQARRTSQEQQAQHVTLIQQQAGLPQAQPLTLVHQQPTTQTSQQISVVHQPQTSQQLSIVHQHQTSQAAASLVHQQPNQSQGTQHQTESSQSQSPSSELRVTPNHWYVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMZ5</accession>
    <name>A0A3R7QMZ5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002125">
        <property type="protein sequence ID" value="ROT72645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMZ5"/>
    <dbReference type="OrthoDB" id="6356174at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051560">
        <property type="entry name" value="MAM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282">
        <property type="entry name" value="APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282:SF101">
        <property type="entry name" value="MAM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAM" evidence="1">
        <location>
            <begin position="32"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="1">
        <location>
            <begin position="193"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="44914" checksum="5B69BA85DA6D50E2" modified="2019-04-10" version="1">MNEEGIIALDELLLHEAPCSVVGPTDAPDTRMICDFEEDLCGFKLEDEHGKWIWTYPNSPDNDFPHPSRDHTYYTGYGHYLAAPLEDDREGVVGRVVSPEYSQERHEKQCLVFWYIHNGNTDRDVLEVYVKHGLTVFPRAAWRENANHMYTWMRANIAIPSGRSHFSVIWRAVQRKRDNKGVFALDDVEILEKECPNIVGTCGWQNLNQTENVTDETDWIQSSGDDGLNGISPPDDHTGDTKGKFLYVDGKNGTTGTAVLESQLLTPEQHSDFCFSFWFFIDGVPADEISISSVVSMAPKKSFGSMTVLARGGLRANCTSAAEEPRQLPSSPWTISPSRGSLSAKRPLSFTTHNSGHAYALGMYLYPRRLLWDDTHWAGLWDFNEDNSALNHGAGRTPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWK1</accession>
    <name>A0A3R7QWK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative prolow-density lipoprotein receptor-related protein 1 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001061">
        <property type="protein sequence ID" value="ROT80826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWK1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="571"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="596"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="666"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="884"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="895" mass="96531" checksum="B2390E544E97D08F" modified="2019-04-10" version="1">MVLGKDELILAAASPSSEATTSGGATSSPSEAAISPSSEATISGGSASSPSGAAASPSSEATTSGSAASSPSGLRPHPPRRLLPREVRLPLPLGLRPHPPRRLLPREVRPPLPLRLRSHPPRRLLSREVQPSLPLGLRPHPPRRLLPREVRPPLPRGLRPHPPRRLLPRECGLLSLGGCGLTLLGGYYLGRCDLLSSEAAPPRRLLPREVWLPLPLGLRPHPPRATTRDLSLWGCGLTLLGGYYLERYGFFSLGGCGLLSLGGCGLLSLGGCGLTEGEEAAPPEVVASEEGEAAAPEGEEAAPPEVVASEEGESVAPEREEAIAPDEEKAAPLEVVASRRVEAAAPEGEEARSPEGEEAAAPEGEEAQPRGRGGRSPRGRGGRSPRGKGGRSPRGRGGRTSRGSSLRGGPRGRGGRTSRGSSLTLGLRPHPPRRLLPREVRPPLLLGLRPHPPRRLLLREVRPPLPLGLRPHNPRRLLPREVRSPLTLGLRSHPPRRLLPREVRHFFTRGIRPPLPLGLRLHPLFGGYYLGRFGFLSLGGCGLTLLGGYYLGRCGLISLLGCSLTLLGDYYLGRCGLLSLWGCGLTLLGGYYLGRCGLLSLWGCGLTLLGGYYLGRCDLLSLWGCGLTLLGDYYLGRCGLLSLWGCGLTLLGGYYLGSAASSPSRAAASPSSEATTSGGAASSPSGAAASSSSEATTSEVRPPLPLGLRPHPPRRLLPREVWLPLPLGLRPDPPRRLLPREVRPPLPRGLRPHSPHGLLPREVRPLLPLGLRPHSHRRLLPREVRPPLPRGLRPHPPRRLLPREVRPPLPRGLRPHPPWRQLPREVRPPLPLGLWPHPPRRLLPREVRPPLPLGLRPHSPRRLLPREVRLSLPRGLRPPLPRGLRPHPPRRQRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWY7</accession>
    <name>A0A3R7QWY7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001001">
        <property type="protein sequence ID" value="ROT81226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWY7"/>
    <dbReference type="STRING" id="6689.A0A3R7QWY7"/>
    <dbReference type="OrthoDB" id="203908at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052100">
        <property type="entry name" value="SV-ATPase_mito-regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44054:SF1">
        <property type="entry name" value="SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44054">
        <property type="entry name" value="SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="250" mass="26437" checksum="C3FFB47E9D229371" modified="2019-04-10" version="1" fragment="single">VEEGPAPAPPLKGQVTVLVKACGLNFYDIYVRHGLNPEIQPPCTLGLECAGVISAVAEDVQSLKVGDHVAVHCPQAGACTQQITVDEESVIVVPRDISFEVAASFTIAYQTAYFSLFHLGGLRPGGAVFIHSAAGGVGWAATQLAKTIPNVTVLEQPQSKHEAMQENGVDYAIHHGQDYEREILKVRPQGVSIVLDSLAGAEFTRSQNLLEPLGKVVLIGAKGMMRGSIQSACILKPGGTQKMSLLSLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SL31</accession>
    <name>A0A3R7SL31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003093">
        <property type="protein sequence ID" value="ROT65381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="782"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1210"/>
            <end position="1847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1860"/>
            <end position="1896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2103"/>
            <end position="2122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2156"/>
            <end position="2338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2435"/>
            <end position="2461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2500"/>
            <end position="2531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2548"/>
            <end position="2570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="676"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="920"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1265"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1329"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1343"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1356"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1384"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1413"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1463"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1624"/>
            <end position="1634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1644"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1679"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1696"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1725"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1803"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1819"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1884"/>
            <end position="1896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2105"/>
            <end position="2114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2168"/>
            <end position="2188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2189"/>
            <end position="2202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2227"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2249"/>
            <end position="2262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2281"/>
            <end position="2293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2304"/>
            <end position="2318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2438"/>
            <end position="2461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2550"/>
            <end position="2570"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2804" mass="307879" checksum="7E8715972F262784" modified="2019-04-10" version="1" fragment="single">KRLKDGEGEEAGVSLAAVTPDDSALAPATAPDTSVIADVSTLNQEPELDVDRSDQVDVEASQVDEELIQNLTQQTPSQWMDVSDVDLLNVMAGLADGSQIVSPDDNDAILSTQRPSGSCATNEVTIQNHPSEGREDEEESDEEETRHMTQRIWDSILPAKEEEEEEKEKEREDEEGEINDSQKSSTHEDSLRDQSLLREDKDIEDLVEGPGCSLPQLDGAIDCVRLPKSEARTKECALRETFVPSGSAQTVERNTVIMNIAQNCDSKVLSKHCDNFLSGNKQKCDREKSESKEAISLKRKSLPRTKEVYSKKKIERKLSSETSDEEVFTIPQFDGANDIVFHSRKQKTSSNSSAQHTGQGSLSQRPSLPQMQYTSNSKSITAREAIRENILKKKRGEVSQVVHPTQHRRQDPQVPQQRQRCNSQPVPYPSAPQAPVPSSHNNRVPASMSSSVPSDINMDRMLGRRMETSSNMASGQFMQSSTAAREENYSRSNARNQFSMKTDSMGHTDRREGNIASGVSQGFQRVSQSQERSKSSKKNRKGQRSEFRDPTVPSHVSSKTSDSMGMAGPINITPIASGMPQEFPGIGKALVVPALVTNKRVNVTNSHVMLSPNMVMQNSGNVIFNQSSFESGNSQQSPSVMMVQPTIEHENSGGRRHAQMNNPLRHTTESSDRSTSKSASSSSGSFRPSRSSKYAEGGHQGFSGSNLAGAPGPLKSIMRQHSDQSVYSPISDESDIEISSTKNAVAPKSSESAAEKSSKQSDILQQALQALDMSLDIDIEPMDSENYNVQKESLSATASQSRPSPVGRHSRTSNQNQQSVSHSMLDPAKSSGAEGSSSRFENSKWSSQESERSRSHHSKTNQSKSTTHGEHSSYAREMEGRHLSQKARGKPSKSEVQSVKRSEREAKAAPTGQTLRTNEVSDSSSSSSHSESGSERQGGSDSSRSSSPESGIRTQKLQAVRERHMTTPITQSRRFSRVASTDVFDMDYDMTPQTPGSDLPVHDPVTNPAAGVLNQVPKSQKNKPSHAATSSKKSESAVPHRKMSDCDNPDWFNFDCPPTPGDPVSSKHGFSEPSSLVQKTDAKKVNNRQTSAKAQSSSGETAQASNGSSESKRKSKRKMARLFGSFSPPASSSGSTPTQEEGLQVTNIKPVNVEPFVDTFDSDDNKTPERPQTPGREVRDDHTFRTPSSSQKQHSHDYIYDYYMNNFPERPLTPGGNHEVQNIFSNDSGDDAARNPYQQFESIFDPDLMASSLPERPRTPGGGSSPTSMCQSLSQPSDISSLYLPDQQFKSPSHARMNLFPASPVPVEPEPVVKESPKTQRFPSKSNLPKHSSQPSHSSHNHPPSDRKEHEKKENYSTLESGLSPKGTQFSSRNRASKEEKKALQLSKSAAKSMDSSPFIGIGKVPAPLSPLREPHTSKSKVEVESRSRYPSEQKRQARQNVHGRAGGEVETISEQQNISHLKKGEEEVGHGMEYEEMQKSKKSKTHLESMKHRGRSAMHHSFSEVLEDPDSRRKNQPFQNTALEGEAVADRMQGNVLRSEGTHRPSNQQAASLASRKDRGNIPRPSSQAGSHFHAPQGSHQHHPDSRSPPRSRYQQHMDSRHAQHGNRFRQSGSGSRGPSAENLPQQSNTTEISPGRHRPKFSQGNRQQVSPGNKPGPPQANRSMSGNRQPPPQLERSQISSSNRAQSSQGSKSLVSPNNKQQFLQGKRQQMAPGNQRHLQQDTHSQATSHMQSSSSRWSKPHNYNKAVETSSQQDTEEIDFSPHPDVSSQQGKKAHRIEGHFVPPQRLRQGQDISTKDNTKSGWNKTENSSGFKSGRPMERNEPQPFRREKSAGEEMTKMRSLKSIPSLASTFCKAKAPGRETNPQSQGFPHKEASGFTNITERREEKKDGRDILDHDDFNLPFIDTSLPLMSPIPCTPAAHRDDFCSVSDTGNNAFPLMDSIQPPMSPMAPTPRHQPHEDINLRLQPLSPVEPIVNLSASMTPQSSAPFILPSAPGPVMSPIPPTPVRTTSPVRMSPMPVYPSMLGPIVSPIANTPTHSIGESFSILSPVPSTEDMSSHHAHPFGSLREAAEHFTVQVAMSPMPQTPAHIAQMPQQLPLGKNPTSTAQTPAMSPIPPTPAYSETDDFSLPPMMSPMPVYPSVGPLVSPMPHTPSHYGVESNEPPMMSPLPSLPSAPGPVMSPLPQTPSYAPQPYVSQSPLYMPYTPHAHAPQTPLHTPEASVHTPETSVPSVLDTTSTQAIASSPTVQSESSAQQTSTSPIHATESHKQKLPSLQQSPEDRSQFDEDSHLKSGTLAHPQDSKTFPSNTQAITGSQTPVTPHPPHSVSPLHGPMTPLHPPMTPLHGPMTPLHGPMTPLHGPMTPNQGPTTPLHAPMTPLHAPMTPLQPPITPLQAPLTPISSAQTPHTTPVTSDSLQSQEHTLHKASQALEGAVVSETSTQSNETVTSVPTSIMDEQNPNRPALLSANVSDMETAEVPQVNTAESEASMQNVPLFTLDKTNITPAPPSAVQLDLPANDSQKDSSCSTQPPQLPPVLLHFLEQEMQSDAENKENESQNATKDNEVASDTDKSGNARFFDFTHCADHTYVFDFTHCADNTHFSDFTHYSGNTCFFDFTYCADHIYFFDFTRCTDYTYFFDFTHYADNTHFFDLTHCAGNTYFFDFTHCAGNTHFFDFTHCADNTHFSDFTHCASLTCADNTHFFDFTHYAGNHSFTSSVSKFITINGTGTIFISTEADYNFSSVHLCSHVIAFCQCPVRVTISTCIITICSYNFRINRNFFTFIKHSSNFTIYTSITPHASRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRZ2</accession>
    <name>A0A3R7SRZ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Myotubularin-related protein 10-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002158">
        <property type="protein sequence ID" value="ROT72428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SRZ2"/>
    <dbReference type="STRING" id="6689.A0A3R7SRZ2"/>
    <dbReference type="OrthoDB" id="271628at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14537">
        <property type="entry name" value="PTP-MTMR10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030564">
        <property type="entry name" value="Myotubularin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010569">
        <property type="entry name" value="Myotubularin-like_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807:SF110">
        <property type="entry name" value="FI17948P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10807">
        <property type="entry name" value="MYOTUBULARIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06602">
        <property type="entry name" value="Myotub-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51339">
        <property type="entry name" value="PPASE_MYOTUBULARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myotubularin phosphatase" evidence="2">
        <location>
            <begin position="181"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="680" mass="77120" checksum="07981FAB169A56F1" modified="2019-04-10" version="1">MLNYKRPVDVPEEVDNGKVEPNLLPGEIKIAEANNVLKFAPLKTNKTGISGTLFVTNFKVSFVTSLPVDSKEAELHERSLQSHYLGVHDVCLSEVDLVYQISEGSTKKKRLLYNAPLPARVSGLQLVLKNLRVFNFCFKFTPAGEDVRIGQALLHHAFPPSIDHLFLSCGHPSPFTGIPEFCLAQDWEKELQRTRCPNWRVSKHNEFFNLCSSLPTVVVVPRDLLDAQLEQAAQHFQGTRPPVWCWGALGGAALVRMAQISPNISDKISVTKSMGTLQRRKLEEESQQQENRMMGLVHRCHPKKLQPTIIDLDQKLPSLKDVNISYIKLRELHTPDDPTQFWEQDRHYFSRWESSRWLSYVSKCLEVAQNAASAIAHHNSSVILQESEGRDMSAVISSLVQLLLDPQVRTLRGFHSLIQKEWVALGHSFCSRLGHTRNQPEEQSPVWLLFLDCVHQLSLQHHAALEFTSEYLLALWHASHCSLHSSFMFNSVNAKYSAKAVLQRENPQQPVYLRPVWSWWAEDHDWLGSEQNGSSESVKGRRSAARDLFLNVHYIQNLMESLVVSGALGRLRDPVSSAHHTWHRIQYLLGDSGPLPYDPNAPLGPLQIDASLRVDVALSSLKPWHECFSGWISEPSVTINEIDSLSRQSTTTVQHWEHVRQIYYTIKSHLSETLTNGVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ST20</accession>
    <name>A0A3R7ST20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001993">
        <property type="protein sequence ID" value="ROT73763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ST20"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="44480" checksum="90EAB12EDE8AA08E" modified="2019-04-10" version="1">MADLSFRYKTFFSSPPQVGVPLSFRRQQEPGQLHLYRPFIFRGRPTNSQTRRFRTEQPLLTKAATTKDRHSSGRVGNSREECGRPSHGAGLLEWPRARRRTSLRTASPSAWKPSAACRPEGSLSSSDLFLEYLSHFALGSRPIMSDRSLPLLPPSFPLLPLLPSSPSFSPSLQVLFPPAASYPPPSSPCPLFFLLSPSSSPLSPFPFLSLLAFESPFNPASSLSPILVLSSPLLPPPPLPPLFSTHLLSSHFLLSLLCIPPLLLFLPPIPPLSPSPFSFTLPLSLLPSLPSRPNPLLLLPSPFLLLPPPPSLSPPPPPSSPHFLLPLPFFPSTSFSSPPSPSPPSPLSPLFSSSPSPPLPLPSLPSSLAPLLPLPLLIPLLPSSSLLFLWRSFLFLPQELGGAPAALQHDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZ13</accession>
    <name>A0A3R7SZ13_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acidic mammalian chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024337</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000817">
        <property type="protein sequence ID" value="ROT82482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZ13"/>
    <dbReference type="STRING" id="6689.A0A3R7SZ13"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000003">
        <property type="entry name" value="Class V chitinase CHIT5b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF390">
        <property type="entry name" value="CHITINASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018597997" evidence="7">
        <location>
            <begin position="22"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="8">
        <location>
            <begin position="59"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="416" mass="46876" checksum="9DA9A771B9222936" modified="2019-04-10" version="1">MVVVVVVLWTCVAYVLWQCSAGESHARIYIDDLLKRHQKLISGSEPNTQTENIVVDSNIKRVCYYALPHVNTTVATLSPRDIPPDLCTHIIIIGAEIHDNKIVPVEENDLKVFAEVVALKEVNPSLRVLLCLGGDFSELVRDPTSVAVFAYNAQQFLINYNLDGIDLDWEFPAWPAWKKNVLEKKWFTYFVLQLNNALKLAAHPSFLLSIAVGTPKPIVDHCYEVDQLAKYVDFVSIMGYDYHMYQSYLPFTGHNAPLAERHDEIGYFSTLNIEWATQYWLQKGMPKEKLMVGIPTYGRTWRLLSGAWHNVGAPAVGTGMLGGSLTYTEACIFVKEGATAYFDDESKVPYAVRGRDWVSYENPASIRAKAEWVKTSGVAGVMTFDLNSDDYAGLCSRKKFELHNIIKDTLSDIPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZT8</accession>
    <name>A0A3R7SZT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023432</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000693">
        <property type="protein sequence ID" value="ROT83392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZT8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="578" mass="59457" checksum="03E29CF5748CFC97" modified="2019-04-10" version="1">MPSCPMALLPRLPCCPMPPSDAPPCPDARCPPCPMPSCPMPSLPRCPAPMPSCPMPSLPRCPPCPDAPPPDASLPMLPCPPAPPMPSPAPDALPARCPPCPMPSRADAPPCPGNAPPRPMPSLPDASCPDARCPPCPDAAPCPMPSPARCPPCPMPSLPRCPPSMPPCPDARCLLPDALSCPMPSACLPMPSLPRCPMPSPCPPARCPMPPCPMPSLPDACPMPSCPMPSLPDGPPCPDADALPAPMPSLPSLPDSLLPAPDAPLPRSLLPRCPAPMPPAPNALPARCPPAPCPPARCPPARCPLPRCPPCPMPDALLPDALPAPMPSLPPARCPPCPMPSLPRCAADALPARCLSLPRCPPARCPMPSLPDAHPCPMPPPARCPPARCPFPAPMPPSRNAARCPPCPMPSLPDALPARCPPCPMPSLPDALPAPMPCPPCPDALPARCPMPCLDPMLPCPDALPCPMPPLPRCPALPPNALPAPMPLPPRCPAPDALPARCPPCPMPSLPLPSCPCPPAPCPPCPDALPAPMPSLPDALPPDASLPDAPMPDALSAPSPMRCPPLGSFPFAREKQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZZ8</accession>
    <name>A0A3R7SZZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemocyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023279</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tyrosinase family. Hemocyanin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000671">
        <property type="protein sequence ID" value="ROT83548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZZ8"/>
    <dbReference type="SMR" id="A0A3R7SZZ8"/>
    <dbReference type="STRING" id="6689.A0A3R7SZZ8"/>
    <dbReference type="Allergome" id="12159">
        <property type="allergen name" value="Lit v HC"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005204">
        <property type="entry name" value="Hemocyanin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF5">
        <property type="entry name" value="FAT-BODY PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03722">
        <property type="entry name" value="Hemocyanin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00209">
        <property type="entry name" value="HEMOCYANIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00210">
        <property type="entry name" value="HEMOCYANIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="2">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="649" mass="73484" checksum="D3B14B22C9D6CDDC" modified="2019-04-10" version="1">MIVKLHALRVYIDGTTGSLVTISTMRVLVVLGLVAAAAFQVASAGSYSDGGAAVQKLVQDLNDGKLLEQKHWFSLFNTRHRNEALMLFDVLIHCKDWASFVGNAAYFRQKMNEGEFVYALYVAVIHSSLAEHVVLPPLYEVTPHLFTNSEVIEEAYRAKQKQTPGKFKSSFTGTKKNPEQRVAYFGEDIGLNTHHVTWHMEFPFWWNDAYGHHLDRKGENFFWIHHQLTVRFDAERLSNYLDPVGELQWNKPIVDGFAPHTTYKYGGQFPARPDNVKFEDVDDVARIRDMVIVESRIRDAIAHGYIVDSEGKHIDISNEKGIDILGDIIESSLYSPNVQYYGALHNTAHIVLGRQGDPHGKFDLPPGVLEHFETATRDPSFFRLHKYMDNIFKEHKDNLPPYTKADLEFSGVSVTELAVVGELETYFEDFEYSLINAVDDAEGIPDVEISTYVPRLNHKEFTFRIDVENGGAERLATVRIFAWPHKDNNGIEYTFDEGRWNAIELDKFWVSLKGGKTSIERKSTESSVTVPDVPSIHDLFAEAEAGGAGLAKFESATGLPNRFLLPKGNDRGLEFDLVVAVTDGDADSAVPNLHENTEYNHYGSHGVYPDKRPHGYPLDRKVPDERVFEDLPNFKHIQVKVFNHGEHIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T042</accession>
    <name>A0A3R7T042_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000650">
        <property type="protein sequence ID" value="ROT83684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T042"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="479" mass="51341" checksum="5D76F47907684110" modified="2019-04-10" version="1" fragment="single">RSLHSAPTPPSRSRTAIPFSPTPAIPLRHRHPASRTPPFSFPTTAIPCLDTVILAPRHRHPPSPTPPSAPDIPLPTPMPLPTHSRAIPLPTPPSRSIPPTAAIPLPDTAIPPTPPSAPDTRHPLSHRHSRSRHRHPAPGSPAPDTAIRLPPPLPARHRHPAPDTAIPLPDTAIPLHPLHRHPAPDTAIPHPAPDTAIPLPTPPSRSDTHPAHRFTASRPPPPLRHRPPRSRHRHPDSRHRSIRSRRTAIRSRSHASHLALRRPPSPLPTPPRHRHPAPGTAIPLPTPPSRPTRHPAPTRHDTAIPPPTPTSAPDTAIPLPTPLDPAPDSSPPSAPDTAIPLPTPPSRSRTTPHIHTPSRSRHRHPAPGHATPLPTPLPTPPPTPTPAPDTATPLRHRTSPDTAPLPTPPSRYRHRHPAPDTAIPLPTPPSPASDAAIPLPTPPSRSRHRHPPSNVPLTPGSTLAVTIPADITADIIHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SA18</accession>
    <name>A0A423SA18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysialoglycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004422">
        <property type="protein sequence ID" value="ROT61016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SA18"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039330">
        <property type="entry name" value="CAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37354">
        <property type="entry name" value="CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37354:SF1">
        <property type="entry name" value="CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="944"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1066" mass="123073" checksum="CFE90854F623B542" modified="2019-05-08" version="1">MSPRRTPKRWPISPKDGQGEVYEPKKDAKEWSISREGRPREVYEPKKTQEVVYKPEKDGQGEVYEPKKDAQEVAYEPKKDVQEVAYEPKKDGQGEVYEPKKDAQEVVYKPEKDGQGEVYEPKKDAQEVVYKPEKDGQGEVYEPKKDSQEVVYKPEKDGQGEVYEPKKDVQEDCQGEEYEPKKDAQEVAYEPKKDAQEVVYKPKKDGQEVAYEPKKDVQEVAYEPKKDGQGEPEKDGQGEVYEPKRTPKRLVYKPEKDGQGEVYEPKKDFQEGEVYEPKKDAQEVAYKPKKDGQGEVYEPKKDAQEVVYKPEKDGQGEVYEPKKDAQEVVYKPEKDGQGEVYEPKKDSQEVVYKPEKDAQEVVYKPEKDGQVYEPKKTPKRWPISPRRTAKGRYMSPRRTPKRWSISPRRTAKGVYEPKKDAQEVVYKPEKDGQGEVYEPKKDSQEVVYKPEKDGQGEVYEPKKDAQEVAYEPKKDVQEVAYEPRRTPRGGRPREVYEPKKDSQEVVYKPEKDGQGEVYEPKKDVQEVAYEPKKDVQEVAYEPKKDAQEVVYKPKKDGQGEEYEPKKDAQEVAYEPKKDAQEVVYKPKKDGQEVAYEPEKDGQEVAYEPKKDAQEVAYEPKKDVQEEAYEPKKDAQEVVYKPKKDCQGEEYEPKKDAQEVAYEPRKDAKRWDAKNKPKKDGQEVAYEPEKNAQEVVYKPKDGQGEVYEPKKDAQEVAYEPKKDGQEVVYKPKKDGQGEVYEPEKDGQEVAYEPKKDAQEVAYEPKKDAQEVVYKPKKDGQGEVYEPKKDAHEVAYEPKKDAQEVVYKPKKDGQGEVCEPKKDAQEVAYEPKKDALEVVYKPKKDSQGEVYEPKKDAQKVAYEPKKDAQVVVYKTKKDAQGEVYEPKKDAQEVAYEPKKDAQEVVYKPKKDGQGEVYEPKKDAQEVAYEPKKDAQVVVYKPKKDGQGEVSLYEPKKDGQEVAYEPKKDGQEVAYEPKKDGQEVAYEPKKDAQEVVYKPEKDGQGEVYEPKKDAQEVVYEPKPVFRLHSGGERARRIVSVQSSDVLRGPLAWSRRRNEIWEERAKGKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SD99</accession>
    <name>A0A423SD99_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative receptor-type tyrosine-protein phosphatase V-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019991</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003784">
        <property type="protein sequence ID" value="ROT62176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SD99"/>
    <dbReference type="STRING" id="6689.A0A423SD99"/>
    <dbReference type="OrthoDB" id="6430956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050713">
        <property type="entry name" value="RTP_Phos/Ushers"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46957">
        <property type="entry name" value="CYTOKINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46957:SF3">
        <property type="entry name" value="CYTOKINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="648"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="704"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="742"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="924"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="35"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="136"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="350"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT62176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="957" mass="103006" checksum="56E021228A533639" modified="2019-05-08" version="1">MEILKKGLDAVRMSRGTYPASFIDVLRMMIENFAPPQPLEASCSSTPPAEHSIVVTWSAPNTFCNVSAYNVTYIGDVLWSDEEQVGTLQTSEEMANLSSLTSWTKYHVCVAGIVLDDFVGEQSCCDAVTQEAASGPPALFNVSGTSSSSISVFWEEPRAQNGKIDFYQLQFGGESVQVENATEFTLTGLAKNSKYIISLKFLGLQEATTCFNATGVTGRHASATQKAVEPAGTRRAERLLPASLMHGDPWSPEASVRVAARGRPRKDAEGKAKAANVGAIVASVLSGLLIVGVGVAAFIYRDKLRNVIARKTSKREPVQEHPLSTTSTAVGKDQLRSYIDGLQEDTQRGLEEEFARLKQQCPKPSTYDAEMDVNKPKNRFSNILAYDHSRVRISKREGAAQSDYINANFIKDHAGRPGFVATQGPTEDTLDDFWRLVWEQKVYTIVMLTSLMEKGKVSRPGEPGRPRCSSCSSWVVGYRGFCSSWVMGYRGVLFRSGGLFIPWGTGVFVHLGPGVLFILGHGVRGVLFILVMGYRRFCSSWVMGYGGFCSSGSWVQGFVHLGHGVQGFCSSWVMGYRGFVHPGSWGYRGFVHLGSWGTGGFCSSWVMGYGGFVHPGVGVMGVTGGMSSAGSWGTGGFVHPGHVHGVQGVLFILGHGVRGVLFILGHGVQGVLFILGHGVQGVLFMGSSSWVMVRGFCSSWVMGYRSFVHLVMGYGVFSILGHGVQGFCSSWVMGNGGFCSSWVMGTGFCSSWSWGTGVLFIWVMVRGVRGFVHLGHGVRGVFVHHGSWGTGGFVHPGHGVQGFVHPGSWGTGGFVHPGSWGTGGFVHLGSWGGVTWGKGVLVHPGSWGTGVLSSWVMGTGGFVHPGSWVQGVLFILGHGVRGFLFILGHGVQGVLFILVMGYGFCSSWSGVTGGFVHSWSWVRGFVHLGSWVQGFCSSWVMGYGGFCSSWVMGYGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDD3</accession>
    <name>A0A423SDD3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chloride intracellular channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003758">
        <property type="protein sequence ID" value="ROT62227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDD3"/>
    <dbReference type="STRING" id="6689.A0A423SDD3"/>
    <dbReference type="OrthoDB" id="1935530at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03198">
        <property type="entry name" value="GST_C_CLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43920:SF5">
        <property type="entry name" value="CHLORIDE INTRACELLULAR CHANNEL CLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43920">
        <property type="entry name" value="CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="21712" checksum="64FA2FAC2235FBEF" modified="2019-05-08" version="1">MEVAPSPRSSLLSRSNFEATPPPILIDNGLAVLENDKIERHIMKNIPGGHNLFVQDKDVAQRTENIYSRFKLMLLKRDDTSKNTLLSLLRKINDHLGERGTRFLTGDTMCCFDCELMPKLQHIRVAGKYFADFEIPDELEHLWRYMYHMYQLDAFTQSCPADQDIINHYKQQQVKLKISRINQEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEE0</accession>
    <name>A0A423SEE0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative tripartite motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003633">
        <property type="protein sequence ID" value="ROT62556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEE0"/>
    <dbReference type="STRING" id="6689.A0A423SEE0"/>
    <dbReference type="OrthoDB" id="295536at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12889">
        <property type="entry name" value="SPRY_PRY_TRIM67_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000178">
        <property type="entry name" value="E3 ubiquitin-protein ligase TRIM9 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF15">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="55"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="2">
        <location>
            <begin position="128"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="323" mass="35368" checksum="CF3FE8C07DFE173B" modified="2019-05-08" version="1">MEAQEILEERVNAMSRDWDQSMVSEPRVPPHFNLTLDDKTLLTAIQQLTFIQLKPPGTPSMIPEECSAENNSVTIAWAPHHTSCVTGYTLEIDDGAGGAFREVYSGEQTVCTIDGLHFNSIYRARVRAFNSTGNSPFCEPLCLQTAEVAWFTYESSHPDVTISATGFTVSCDSYEHRVVLGSVGFSRGAHYWEYTLERYDGNADIAFGLGRIDICKEMILGKCGGSWSMYIDSERSWLMHGGEHFNRTAGGVRAGDTVGLLLSLPEKTLSFFVNGELQGYVSLAGVTGVLYPAVSLNRSVVLNLQTGLHPPQALVETPVAAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SF16</accession>
    <name>A0A423SF16_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003546">
        <property type="protein sequence ID" value="ROT62810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SF16"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="433" mass="48049" checksum="01C43D2ECF6906FE" modified="2019-05-08" version="1">MLAGIFFNPSLEFWSRWVAPLFPFLSSSLFLFIYACHFPGRPKFLIKASRPCHESDPARLSETALARCHKGSFATSPLGLASIIPVFFHVFSFPHSPSPLSSPLSIILTLISSPFLPSSIPPLLFSPHPFYLPSLNYSHPYFISFLYIFYSPRVLRFSPPLLPHFQLSSPLFPLLFLHLFPSSPPHPPLPTSSYPHSYFLSFLPSSILLLSSLHPPSPPLPIIPLLFPLLSSHLLFSSSPPFTPLSPTSNYPYPYFLSFPSIFYSPPLLPSPPTPLPHFQLSPRYFLSFPSIFYSPPLLPHPPPPFPHFQLSHPYFLSFPSIFYSPPLLPSPPPPPTSNYPHRYFLSFPSIYSPPPLSLLVPPGHHKGKPVSRGQRGSAITWITSGLVMTYPTTPRGAGCNIPRDLRASEVNGLGGASVLVNEKGSGSYSIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ00</accession>
    <name>A0A423SJ00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003311">
        <property type="protein sequence ID" value="ROT64161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ00"/>
    <dbReference type="STRING" id="6689.A0A423SJ00"/>
    <dbReference type="OrthoDB" id="8931646at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14809">
        <property type="entry name" value="bZIP_AUREO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039165">
        <property type="entry name" value="CREBRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21552">
        <property type="entry name" value="ADULT RETINA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21552:SF2">
        <property type="entry name" value="CREB3 REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="507"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="653" mass="70458" checksum="C837A14F499470E1" modified="2019-05-08" version="1">MGVDSGMVGGVPIPRGPCNRNPQTHHFPDLSSMALQMDDHSPIPNQQSGNSLGPQWDSNTHFSTLYQDSTGGLSPVGPNSPSLWPPQSMDLDLDIKLEPLDDLLGVDDLLPGHPLGLQSADDALLDDVNLDDLLMPEQFSNAGLEQPNSPITMVTVHPDEVLGMNKGFSTPTSSFHCPPTMAQPVKAESSSLYSLLASSFPPQGGGWRDPLLTSSSLPGQPPNQQLGSIEECPSSNQQQNISQQQQQCSNHSSGSTSALQELLLRSPSTPLSPHSVSSQGAPSPQEPPMGQSVPRPSSLSAANPLLSARLSSSAPTHNFSLEQAWQRREPRQHLLSTGSLAEEFGGSASSLSTVGGILSPAAHDLSIDDAVDSEDESDNEHYDSESDNDSIVSEDTSSISGSSGKKERYFWQYNVQAKGPKGQRVCISQQQRDPHSLPSIMDPVFSPLCSIQGIKHSGKARRGDGNDLTPNPRKLVNIGRELDKLNKTINDLTPVSELPFNVRPKSRKEKNKLASRACRLKKKAQHEANKIKLYGLEQEHKGMLLLLEEARGSLIKKVESGGTAHMPTNHHQALPGTPPQNHQLSVSQHIEKIAKLRSKLRIAGHTTEFVNRVIENCQNGDQSGGLEEITKTFNDTNLANSPTSNGNNGFSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SL93</accession>
    <name>A0A423SL93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative cubilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003165">
        <property type="protein sequence ID" value="ROT64941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SL93"/>
    <dbReference type="OrthoDB" id="6366701at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF37">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="130"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="26233" checksum="BD5DA040835215E9" modified="2019-05-08" version="1">MCALYGGRCLPSDAWVCHALGRPGACGGGSDVCCDECPFKTRSQCLQNNGICKSSCAPDEQALQGGCRGESCICCASCRITPGCQARGGSCVKGVADCPSGFVDAAGCEGEQCMCCLPPPGTTTEAPPVCSGVKEINSTYGVISMGSEVSLYESNLDCEWRIEVSPGHELTLVWLRLSIEYQTECSFDFVELEVQGGSGESSKYCGYDIPSPPTTTHTNPVIVRFHSDSSVTSTGFVLLHYVTPTGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNX9</accession>
    <name>A0A423SNX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">I-connectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016128</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003018">
        <property type="protein sequence ID" value="ROT65893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SNX9"/>
    <dbReference type="OrthoDB" id="6381907at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040017">
        <property type="term" value="P:positive regulation of locomotion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060298">
        <property type="term" value="P:positive regulation of sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045989">
        <property type="term" value="P:positive regulation of striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000147">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000425">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000080">
        <property type="entry name" value="Myosin light chain kinase, smooth muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000119">
        <property type="entry name" value="Sallimus, isoform P"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001163">
        <property type="entry name" value="Sallimus, isoform Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000697">
        <property type="entry name" value="titin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000962">
        <property type="entry name" value="titin isoform X1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF4">
        <property type="entry name" value="MYOPALLADIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="19"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="166"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="266"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="399"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="537"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="675"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="812"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="946"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1090"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1523"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1625"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1736"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1835"/>
            <end position="1922"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="1936"/>
            <end position="2028"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2042"/>
            <end position="2132"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2143"/>
            <end position="2233"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2249"/>
            <end position="2334"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
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            <end position="2476"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="2512"/>
            <end position="2600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1427"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1499"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2360"/>
            <end position="2382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="3123"/>
            <end position="4258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2625"/>
            <end position="2661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1438"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1500"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3125"/>
            <end position="3137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3147"/>
            <end position="3162"/>
        </location>
    </feature>
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        <location>
            <begin position="3187"/>
            <end position="3210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3211"/>
            <end position="3231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3317"/>
            <end position="3329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3359"/>
            <end position="3368"/>
        </location>
    </feature>
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        <location>
            <begin position="3373"/>
            <end position="3491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="3556"/>
            <end position="3576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="3586"/>
            <end position="3597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="3604"/>
            <end position="3615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="3622"/>
            <end position="3633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="3716"/>
            <end position="3754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="3843"/>
            <end position="3858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="3934"/>
            <end position="3947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="3964"/>
            <end position="3989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="4134"/>
            <end position="4160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="4258" mass="477660" checksum="786E2B0BE97DB4B0" modified="2019-05-08" version="1">[encoded data, 4258 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SU85</accession>
    <name>A0A423SU85_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SU85"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="384" mass="44344" checksum="40564CF3B6DEB87D" modified="2019-05-08" version="1">MECTEDREIQELRRQLQQRDQELAEVRRLTPSVQHTMTRCQDHLQQPPVINGSRSPLQPLPRSRPHMPVPEQQLYLERQHTYDPQTSLPQQFQPRSLPQCPQSAHPSSQLSGTPFSYVFTRETVPHFKGDTSASQPLKKNQAIESWIRTIENIVKPATSEMFIQAARANCRGPAELIINSPLFDSITEWYTFKAALRSKFRGTYTSSDFYKVLYDIRMTPSQAPMDFFLQLEGHVYQGYRDHREAIGDPSELVKRVFLSGIPAWLQDFLSVKEDGSPTQIAETAQCIWNSRNGIRHSDTSPAEENPYHPNRPPWGRDLYAMPVAAERSSPPYHRPPVKERCCEHHRVRTHGTSECRAKAEILDPQSPRRRLQRSRTFGERLPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVF4</accession>
    <name>A0A423SVF4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Krueppel-like factor 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013668</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002706">
        <property type="protein sequence ID" value="ROT68216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVF4"/>
    <dbReference type="STRING" id="6689.A0A423SVF4"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000007">
        <property type="entry name" value="Basic krueppel-like factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF158">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="331"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="361"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="96"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="49360" checksum="6C1DF0991CAE73A3" modified="2019-05-08" version="1">MSFIVFLFIGCAQHRFSFPSRSFPFLFFHPFPLPRPLTKALSPAAPSAAAWLLLARPLARAGRASPRARPRQRPFARLRVARAHHLRRLVRRHGLRRRPLHAAPHGAGEPLPHAHALPQPHGALPSLHPPGQPHALPPAPSMGRPATSMPPMCELAEGAMVSPLAAHAALPPTPPHHDPKYDYGAAGHAGGAGGYEAPSCRLKAEFGDFPHALGPRTGVKRAFPEASASQAKYACMGSQYRREEAAYAGVGAPPPLQYMGASAHQGATPQYVLPPTPPQYPAGPHTLHPLPAHHSDYAATSTGWTPTHTSYGAYTQYLDFSACPPAKVIIHKCPYEGCVKTYIKSSHLKAHLRTHTGEKPYTCKWKGCGWKFARSDELTRHYRKHTGDRPFQCRLATSRSEAPPAQGAAGLRALLPALSEARLRRPDLGADAPVGLSARSIWRFGAIESPRETSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXY7</accession>
    <name>A0A423SXY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012923</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002621">
        <property type="protein sequence ID" value="ROT68928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXY7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41730" checksum="1A1478EAA47726EF" modified="2019-05-08" version="1">MRACRPRDLGNYAKKSPYMAARRPYPAPLNLKTSRTLPPQQAFPNFHYFPLFSLLTSIIFPRDIIIAGILALGVVTINIRRHIRRHFAFVRVISLSFAASSEAITTSSLAAWRVTTSSTSDGVRIHQPPKGSRPLSPRPERSHPPNAPPPRRIASPSSEGPAAPSGCHSLPFPSLPFSVFVSLHFPSPSSVSPILPPFFCFVSLFCHLSIPFSFSSLSPSLLSHLSSSPPLLRPDLASYGLLAVAIGTHSAPFPWSYGRKLWVADTKRRGDGWTKTEKKREKMQQNQMEVMLTHKPTPSFRHLQQERNFPHRSTTKTSPHRSNRNGTPIALQRDVPPSLYNKDVPIALALQPTPPSLYNEDVPRNVPSLYTTKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZK1</accession>
    <name>A0A423SZK1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbohydrate sulfotransferase 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002545">
        <property type="protein sequence ID" value="ROT69609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZK1"/>
    <dbReference type="OrthoDB" id="6138663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019564158" description="Carbohydrate sulfotransferase 5" evidence="2">
        <location>
            <begin position="29"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="41044" checksum="121FAA06A76636D3" modified="2019-05-08" version="1">MMMVPRPVRHFGQLLIALLFLLGIKTWSNSSFEVTQEKGRDAILRKSTNLSGGASLPRAPPEGAAPPAPTSPPAGSTVLVLSSVGRSGSSFLAELLSQRPNTFYSFEPMHYYEKSTRMALSPRLAWDIVEALSSCRLEEHWLRTTARRGLLRSEAGAICQTTDAELAVSCGGESCRNRSHLLVKTIRMRVSWLPELLLRLGPGLRVVHLVRDPRASFSRILHIPRKCSFPQDLFMVDTVKKLFPGAMASVKYEDLCLDAEGVATDLWRFISGDSTAALPPSWARYIQVHTAPSKAGRGAYNTWRDSQKEAEQWRQEIDEDLLLGVEKSCGQVIELLGHNKFHSLANARNWSFPLRRTPRALYSHIDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T287</accession>
    <name>A0A423T287_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011349</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002437">
        <property type="protein sequence ID" value="ROT70368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T287"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001480">
        <property type="entry name" value="Si:cabz01071911.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000931">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BTB" evidence="13">
        <location>
            <begin position="35"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="248"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="350" mass="38969" checksum="BAA5BEBFE8AB4FF9" modified="2019-05-08" version="1">MGETAPDTQLHLRWHSHATTFTTMLSELHHGRAYTDVSLVCDGGIVRAHRAILSLCSPYLAVVLGACPDTDAPLLLPEVPVQDVLYLVSFIYRGQVDVHQQHIASFLNTAKQLHVLGLEEGDRLVDSPSKSEGSSSTSGNVTPDGRIDLNFYLQQAIQSASMPCPLCKKEFKSQSGLRDHIRLHTGERPFECEFCQMNFARASHLKRHRRMHTGEKPFMCRICGKDFSRGDKLKDHLRRHEAEDKLNKIRKQIYHPEDGTAETETEGSVATVNASPQVLTPKSNNTPPDSAPMPPAKRPRGRPPKNSQAHAQYQQAMSQVPSMLVPQSESYMPHMLGVTSIGECILRPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4Q7</accession>
    <name>A0A423T4Q7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Heparan sulfate 2-O-sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_010309</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfotransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002302">
        <property type="protein sequence ID" value="ROT71383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4Q7"/>
    <dbReference type="OrthoDB" id="10019582at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007734">
        <property type="entry name" value="Heparan_SO4_2-O-STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129:SF20">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE PIPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019469102" evidence="11">
        <location>
            <begin position="22"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="341"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT71383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="442" mass="49061" checksum="6F80A8C2880761B8" modified="2019-05-08" version="1">MGILFLLFGIFGYLFVGSQVAETIGEGQSERGSPEEPSDSAKRRVEKSSIESEERPQRNQSEVPQQEAKSAEGEEGGPEGEDYAVLEPPEEVASRAEVPAKVGDVPLGAPRRKVYGAPSRDYEEKMIKALVKEAYMKVTGEGGDEELQQAPAYTLKVEPSSRNVTPADSQLVFFSAVPKCGSSTTGHLFKKLSVLNNYYSLTPQQRIQPVIDEEQQKTLLENLFSLSEKVPVAYTRHLYYFNTTRLGFPRAAWVAIVRHPVERLISQFYYARIPSRYLENKLLQGRMPSAEFMNMTLDTCVPQRDPRCWYREGSRQMLQLSFFCARTPTARPWAAGGRCKWPSTMRRTSTAQSESWRISISPTGSSRSTCRVSSLAPPSAILGTALTPPPSLRRHRKGPFQQPGEQAVCQELDPPHDGELPEGGPRPLPLPEAETPPSGPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T607</accession>
    <name>A0A423T607_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative WD repeat-containing protein 61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010017</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002268">
        <property type="protein sequence ID" value="ROT71658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T607"/>
    <dbReference type="STRING" id="6689.A0A423T607"/>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="226"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="310"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="345" mass="37960" checksum="3A752E7063E55AB6" modified="2019-05-08" version="1">MSGALFSLLHKRENSHSEGIWACAWGHYVPKDKSKESTSEDKEQENGEENKENEENEKDRDNLPDTEQRYVVSGGLDDLVKVWRWTGDGVEGELSAMHTLEGHSLGVISVDVNAEGTMAASSSLDSTIRLWNIHSGEQLQTIDCGPVEAWSVVFSPDGNHVASGNHAGKINVYAVDGGRHVTTLDTRGRFTYSVAYSRDGKYVASGAIDGFINVFDVESGKLVHTLEGHAMTIRSITFSPDSQLLLTAADDGHMKIYDVKSSHLACTLSGHGSWVLSVDFAPDKMHFVSSSSDHTVKVWDFAQRNCVHTFKDHHDQVWCAKYSQDSSKIVSVSEDKSIIVFNSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7K4</accession>
    <name>A0A423T7K4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intraflagellar transport protein 122 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_009192</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002158">
        <property type="protein sequence ID" value="ROT72427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7K4"/>
    <dbReference type="STRING" id="6689.A0A423T7K4"/>
    <dbReference type="OrthoDB" id="10255582at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045184">
        <property type="term" value="P:establishment of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007507">
        <property type="term" value="P:heart development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008589">
        <property type="term" value="P:regulation of smoothened signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000003">
        <property type="entry name" value="intraflagellar transport protein 122 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000005">
        <property type="entry name" value="Intraflagellar transport protein 122 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000176">
        <property type="entry name" value="Intraflagellar transport protein 122 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056153">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056152">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057411">
        <property type="entry name" value="TPR_IFT122"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056838">
        <property type="entry name" value="Zn_ribbon_IFT122"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF4">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23381">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23377">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25295">
        <property type="entry name" value="TPR_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25144">
        <property type="entry name" value="Zn_ribbon_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25143">
        <property type="entry name" value="Zn_ribbon_IFT122_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT122 first beta-propeller" evidence="14">
        <location>
            <begin position="13"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="55"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 first beta-propeller" evidence="14">
        <location>
            <begin position="196"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 second beta-propeller" evidence="13">
        <location>
            <begin position="303"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="Intraflagellar transport protein 122 homolog TPR" evidence="16">
        <location>
            <begin position="564"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="IFT122 zinc ribbon" evidence="15">
        <location>
            <begin position="998"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1057"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF25144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF25295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT72427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1208" mass="137550" checksum="672BC926F1F3901E" modified="2019-05-08" version="1">MRAVPTWVDKVHDRDKVEQCIYDLCFKPDGSQLIVAAGNRVLVYDTTDGALVQPLKGHKESVYCVCYSKDGKRFASGSADKSVIIWTSKLEGILKYSHNDAIQCMSYNPVSHQLASCALSDFGLWSPEQKSVQKHKSTSRIYSCAWTNDGVYLALGLANGVVSIRNKVGEEKMRIERPGGTNSPVWSMAWNPSKDEPVDVLCVADWGQNLSFYALSGKQVGKERPLGFDPCCVNYFSKGEYLLVGGSNKSCLLYTREGVKLGTIGEQSSWVWCCAARPDSNFVAIGCQDGTIAYYQLIFSTVHGLYKERYAFRENMTDVIIQHLITEQKVRIKCRDLVKKIAIYKHRLAVQLPERIIIYELYSQEASDMHYRVREKINQRLDCNLLVVCTNHIVLCQEKRLQCLNFSGIKEREWQMDSLIRYIKVVGGPANREGLLLGLKNGQVLKIFLDNAFPVSLLKVPAAIRCLDLSSSRNKLAVVDEHNTLLVYDVKTSELLFQEPNANSVAWNTSCEDMLCFSGNSTLNIKASNFPSHQQKLQGFVVGFSGSKIFCLHIYSMSTIEVPQSAPMYQYLDKKMYKEAYNIACLGVTDGDWEALAKASLEGLEFNIAKKAFTRIKDLKYLELIHSIEERSHKGEADNGLFLADILSYEGKFSEAAKLYRKSGSDQSAMNMYTDLRMFDLAQDYLGSDETVDRKQLIKKKADWARNINEPRAAAEMYLSAGETHKAIDIMGENGWIDMLMDVGRKTDKADHQTLSLCAQHLRRLGALTHAAEMYKKMGEMQSVVELYVEVQDWEEAFLWADKHPEYRQLVYVPYATSLAEQDKFLQAQKAFHKAGKPDEAFRVLEQLTMNAVNENRYDDAGYYFWMLSMQCLDIAAEDESEYEAMMTKFKDYQKKASMYYVYHTIQRYMDEPFTSYMPEALFNISRFLMHELMVSHPTGISMFSTLYTLAKQARNLEAFKLARHVLDKLQTLRIPLRFQEDVELAALKIRAKPFHDNEEHQPLCYRCSTTNPLVNNSGNQCVNCCHPFVYSFVSFEILPVVEFVVEEEITDEEAVHLIQQSGSGKTDRVGSANEGEEEQNEDNRWKETESGDAQALMLDGSPSHMQNSDPFTSNLLGFYQGGSEFQPVTLSRQALAAMEPHDVIICRWPKPLRFQFFKNIMPDVPITHCTHCNKMFHTDDYILQVLQKGHCPFCRTPTMENADNHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7X6</accession>
    <name>A0A423T7X6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative lachesin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_009051</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002136">
        <property type="protein sequence ID" value="ROT72556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7X6"/>
    <dbReference type="STRING" id="6689.A0A423T7X6"/>
    <dbReference type="OrthoDB" id="10012075at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000328">
        <property type="entry name" value="CLUMA_CG000981, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051170">
        <property type="entry name" value="Neural/epithelial_adhesion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231">
        <property type="entry name" value="CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231:SF253">
        <property type="entry name" value="DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="9">
        <location>
            <begin position="14"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="9">
        <location>
            <begin position="110"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT72556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="247" mass="27035" checksum="A6C21D92BFA185D7" modified="2019-05-08" version="1">MHIFIIVFSPLVPPTIDDSRSSGDVTVDEGKDVSMTCEARGDPSPVIRWVREGGERFNMNTSQTVDEYLGKTLFIPGVSRNHSGAFLCIASNGVPPSVSKRILLNVKFPPKILDEHASGRVGAALLGVATMTCRFQAQPLTAVRWFKGPREVKGQSASAAVETSKGQGIGEMVSLLTINVEAAIDYGRYRCCLVRNSLGSAEKYFDVYVFTRDVLPNTQEQKLSEVSKKCQVVTQPPFVPWRTLPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8K9</accession>
    <name>A0A423T8K9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002111">
        <property type="protein sequence ID" value="ROT72800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8K9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="975"/>
            <end position="992"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="992" mass="112028" checksum="0890A4E4BC28C0E9" modified="2019-05-08" version="1">MGAESEARESSERTETEARESSEGAESEAREEPSRGEESRVGSEESRVGGEGEPSRRRGRAESEARERAESEARESESERRAESEARESEVERPSRRRVRRRGRAESEARESRVGGEGEPSRRRGRAESEARESRVGGEESRVGRRGRAESGRRGEPSQRRGESRVRGEGEPSQRRGREPSQRRGRASQRRGRAESEARGRAESEARESRVEREPSQRRGEPSPREPEARESRVRGEGEPSQRRGRAESEARRAESEAERAESEARESRVRGEGEPSQRRGRAESEARESRVSEAESRRGEPSRRRGRAESEARRAESEAREKPSRRRGRAESEARESRVGGEGEPSRRRGRESRRRGRAESERGESRVGARESRRRGRAESGRGRAESEARESRVGGEGEPSRRRGRAESEARRAESEASESSRGEGEPSRRRAESEARESRVGGEGEPSRRRGRAESEARRAESEAREAESEARESRVRGEGAESESEGEPSQRRGRAESEAREKPSQRRGRAESEARESRVRGERGAESEARESRVRGEGESRVRGEESRVRGEGEPSQRRGRAESEARRAESEARREPSQGEGEPSQSEGEPSQRREGEPSQRRGRAESERPSQRRGRAESEARESRVEAREPSRRRGRAESEARESRVGGEGEPSRRRGEPRESEARESESEARRAESRRGRAESEAERVGGEESRVGARRAVGGERAESEGEPSRGERASRRREPSRRRGEPSRRGEPSRRRGEASRGEGEPSQSESESERGEPSRRRGRASRRRGQRRVEARESESRRGRASRRRASQRRGRVRESREARERPSQRRGRAESRRGEPSQRRGEPESRRGERVGGEGEPSRGEGGRVRVRGEESRVGGEESRESRRGRAESEARRGGSREASPRRAESEARESRVRGEESESEARESRGRRVEARRAESEARESRVRGEGEPSRRRGRVRGEESRVRGEGEPSQSQSRVRGEGEPSQRRGARESRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8S5</accession>
    <name>A0A423T8S5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fukutin-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002099">
        <property type="protein sequence ID" value="ROT72857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8S5"/>
    <dbReference type="OrthoDB" id="444255at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052613">
        <property type="entry name" value="LicD_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13627">
        <property type="entry name" value="FUKUTIN RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13627:SF34">
        <property type="entry name" value="RIBITOL-5-PHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1145" mass="126052" checksum="ECAFE848A16F6D9B" modified="2019-05-08" version="1">MKPHVSPQRMSKAASARRRARRQASGRGSREGQRSRSVCPEVYFGSHHGWPFYQRGMEAKKECQGVPPLYDVLTVLLPARHWPEQQLRRVRQAIAKEYRVRLVIISKGGITVEDMGGVRAARVAGLSAADDLNEAVKLVETPFVLLGESLAHFSNQSSLERLVRVLDDLDHVQVAGGAARDAQGHWSHGCLQQHMANYQAKYTMGYYHSKYECMYCDDLLTPFVTTTKLLRSLAFSAGLSGQALYRDWFAKVRGAGHLAVLCPDVMFFVGDHVNMTADDWLPVARRWALEKVQAFDGREHFFTCEALDISCSDLMSIVDSFLIPPCCLARIADRVGRALEAAEERNLDYELQAGTVLGAVKFGSVLPWDIDLDVNIECGTQAQWMAVANAHLAGKDCSLKVYEANVYFSVICPKYMVEFVCYARLSRGVLPDEYRNVPTRIEFGGAGRGLEQPPDSTAGTATASRSYGTRSTGGSFPPLKWAGQRAATTTPASGGAVGSPHTTPVSTDPAPQRVEGDPRSFGAGSEESEGAVDEEDTAADEAEGRPREEGVACPPASPSQPCPKCPESEALQVETRRRIARAVADVQGLISRVAGQEGRPGTVTAVDGEWGAASGRVAAELDPRLAATSGAVRERSARLPGLEAPWSVREGAHVCPEAYFGPHFDAPFNQHGMEPEACQGVPPFASVLTALLPAQTWSQEVVTFVVAKIRKLYDIPIIVVASDLGLGGRLGGDARVLVPPPEQSLAEALNDAVGMVETPFVLLGESLAHFSNQSSLERLVRVLDDLDHVQVAGGAARDAQGHWSHGCLQQHMAIYQAKYTMGYYHSKYECMYCDDLLTPFVTTTKLLRSLAFSAGLSGQALYRDWFAKVRGAGHLAVVCPDVMFFVGDHVNMTADDWLPMARRWALEKVHAFDGSLHHFSCELVGISCKSPLGIIRKAFLLPLCCRRLMERYLTHILDYGAAKNLSHELQAGSALGALKMGSYLPWDYDMDVVFECKDFKEWMAIGSLLRSRNSECRATITQHNKYITLYCPNFFLELYCHRYNSTSSAFLPEELRDTPTTIWYAGRWARVTANPGLYSRNKLGLDDLKHAAHWRTLKVTSVGKQKGGYESPGVWRRCRTPAHHACLDRFPADGNLPFLFPFLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8T3</accession>
    <name>A0A423T8T3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008722</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002095">
        <property type="protein sequence ID" value="ROT72871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8T3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="67724" checksum="46059B6858901D98" modified="2019-05-08" version="1">MPICLQFSPPAVSACILSSFYAIHLHAVLILLLYPPACSPSPAVSTCLQSSSCCPRTVSAAAQRHPGRQGLGVPDVARSKVGVKGAPHTAGVASRNSLSPSSSCIRPERCCFVASPLYRERLFYLPLKASLTHPLSYSLPLTLSSLSRSSLPLYVHLSLLLSSPSTLFHALLPSLLPLCLTPLAPQPLSPRQSLGLTPLHISLDHLFISLSLFVPSYRGSVISLSLASFTSFYLSLSLCLLLLSPLPSSLSLSTSHLSPSLPTLSSPSLSHLPSSSPSPSVFSPSHFSSPFSPPPILSPLLPSFVSASLSSIPSLHSLTPSLLLSSPLPSPLNRSYPTRLLSFRLVITALLVILALTSRSPLSYLLPLFSLSSLSPFFFYSLHFSPASLSSSSLSLLSNSLLLFHSPFLYSASSHLAPRVLGFTPSLSPLLSLIRSSPSLRLPLSRPSLSSSSLSLAPDSRLLISQPTSPSSLLSLSRPLRSSSLVSPHLVGLCPLVSFLPDLSSPLSLLSSLNTTSSPLPLLSSCSPLLLPRSPSPSLLLSPLSYLISSSLGQSSSITHSISPPLISVVSLLLSSLFSLPPNLTSPPYLILLSPFPCSSILFPPIFMQLASVFSLSSPWLSPRVHAREQHSRKRNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAS8</accession>
    <name>A0A423TAS8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative UDP-glucuronosyltransferase 2B18-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002018">
        <property type="protein sequence ID" value="ROT73556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAS8"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="140" mass="16364" checksum="7873D6B548A5AFF3" modified="2019-05-08" version="1">MQSLYVLPLCLLPAKNAWLRSMRFGRIHLSWGDVTEESFRESILEVATNPEYHRRISRISRLVHDQPDSPKERAVWWLEYLLRNEGAAHLNQESFARNLSWPQILLLDVLLLTIFILALLGLIVWFVLRRINSSGKSKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCT5</accession>
    <name>A0A423TCT5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative zeta-sarcoglycan</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_007212</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <location evidence="2">Sarcolemma</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sarcoglycan beta/delta/gamma/zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001915">
        <property type="protein sequence ID" value="ROT74279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCT5"/>
    <dbReference type="STRING" id="6689.A0A423TCT5"/>
    <dbReference type="OrthoDB" id="8881719at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016012">
        <property type="term" value="C:sarcoglycan complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006875">
        <property type="entry name" value="Sarcoglycan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039972">
        <property type="entry name" value="Sarcoglycan_gamma/delta/zeta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12939:SF10">
        <property type="entry name" value="EG:4F1.1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12939">
        <property type="entry name" value="SARCOGLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04790">
        <property type="entry name" value="Sarcoglycan_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT74279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="123" mass="13144" checksum="BBFE2201FDD65EBD" modified="2019-05-08" version="1">MPTSFATSWISRHFSSKREGGAVFSGSVQTSHVTAPISESLLLESMTRSLEVSAPQSVALESRAGNISATSLRDFTLRSTGGMIKFDTPNIFVRGLRTSTTETNDAEAALPGVYQASRLSCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIE6</accession>
    <name>A0A423TIE6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PWI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001678">
        <property type="protein sequence ID" value="ROT76231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIE6"/>
    <dbReference type="STRING" id="6689.A0A423TIE6"/>
    <dbReference type="OrthoDB" id="163257at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="PWI" evidence="3">
        <location>
            <begin position="28"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT76231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="181" mass="20230" checksum="3F6D0F3B489F2E9A" modified="2019-05-08" version="1">MADAGFFRGTSAEQDNRFSNKDKKLMKEMKFSESLTKKVDMTKVRLEVIKPWVTEKITTILGIEDDVVIEYVFNQLEAEKQVMPKGVLVPGDGGPQPATCSRLPGWPSLHVGSSLRGLRLIGQGTWRGWMPRYPMDNAQAYCLGDSGHSLEPRRGIRAWMTLGVMSLGCLGIYIIFILQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIT5</accession>
    <name>A0A423TIT5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Trafficking protein particle complex subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005021</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001667">
        <property type="protein sequence ID" value="ROT76374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TIT5"/>
    <dbReference type="OrthoDB" id="27962at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058568">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26283">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="5">
        <location>
            <begin position="257"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="6">
        <location>
            <begin position="550"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="7">
        <location>
            <begin position="722"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 fourth Ig-like" evidence="8">
        <location>
            <begin position="1217"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="975"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="977"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1017"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1357" mass="147923" checksum="BA488390492804DF" modified="2019-05-08" version="1">MRSSVSVILSNPPPDTTMSYPDYCTNPHHHQTLLVLVRQVGSQLKSRSFQKLYERISRVGHVKVSDSNGSQRPVWVTYRREYPVENNDWGDFQTHRRVLGIITIGQVGSQSDLNDICKQHESLKVKYSSTLYDSRCIILGLNPDGTIYEADSRNPSRGTSPEPNGGIDGGSHPPTINGHAQSTHIKKISAGSTDRDSGVYETVSSEDKPTDSDSHSESPQGMSEGMMDLKIDTNHVNGSDSGSESTSEVGCCDDSKMDSPRDSAVDSAPDSAHDTSQSSISTSASQSSRLSLQPPSNFKTRALFYPTSEHAVNIESQLQEFVSSLFWVLESKRLDKSQEKLERPPLLCAPFERKDFIGLDMDSRTNKKRCVGRLRKQLADLTLQAGLPTEAIVHYSHAADTLRNCNDWLWLAACFEGLCAASVVMLYPNLRRSFGLQRYSSLGVGGNQGGSGGIGNRSRNGAVNTNSLPTGLDPIIVKQTSKHCLSPDDIIDKYREAIVHYSKYRNAGVVETEASIKAVHVLIEQKRYLMAAEFLSNVVFINLQLSDEEKIARFNALADLYHQIGFHRKASFFRRVAAMRCVAPQNQQPDWGQCYRLLLQTLEGYKISLDPLEFRKDGSQGWPALQVQILQELVGTSRRMGQNALCTRHQAFLVCAMLPHLSESERKETANMLESLSARSGSGPAPLVVQDTGVIIPAVNFLNIPICRSVRVQPPAVGRKAEKKLSQEAEEDTGPFIFSPFSSLTSNTQRAQGKMDFDWVEGDVCEVILDLENPMPFELKVTSMMLITEGAQFESWTSTVVLKAERGPQPVTLRGRPQGAGELKITGYSSTVMGVSSNCRLKFIPHMKIPFYTINVVSALPFIQILTANSNTGSLGSERAVSEESGNLHLSLSAGETQECSVVLHNISSQPVEEISIALESKMDKTLLSQVFQYSEENIQAQLPIQPGGKASVTLYVYASSDFLCPSRMMDESLETSSLVSGSEPPSLVSGGPSSLPSRQSVATSSTRGARTRRTDSSASLLSSRSGSSVRSGSSSSTQAPSSTARTRTTLNTSACTGRTLEATMQVKYSGGSGLLADYCRSTQVTVTVDVTPSLLVTRWDVLPAELPHQCYVVLDLLNCATHEMDLHYTPTKHILIEAGDSCRVPIPIDRCPLATLTQNGSDSESGWGWSSVLGNHVASLVELRWTQGPCDTPGRASLTGITFPPATHDLITMAPIHWDVQVDGQDVVGGTENTGVVGRTLELCVGVTNTSGAPLPPLSLRLTAFQDHQNGTLNYRLDAKMTTTGATKLTTPQLAEGEEFRHCCGLVFFTAGVYKVEVTCSPAAAVTQTSFYENITPAHQHAWKFAPPLEITVTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKI1</accession>
    <name>A0A423TKI1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Broad-complex isoform A-NZd</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_004410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001585">
        <property type="protein sequence ID" value="ROT76966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKI1"/>
    <dbReference type="STRING" id="6689.A0A423TKI1"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016199">
        <property type="term" value="P:axon midline choice point recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008406">
        <property type="term" value="P:gonad development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035167">
        <property type="term" value="P:larval lymph gland hemopoiesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007526">
        <property type="term" value="P:larval somatic muscle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045476">
        <property type="term" value="P:nurse cell apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007464">
        <property type="term" value="P:R3/R4 cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045467">
        <property type="term" value="P:R7 cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF111">
        <property type="entry name" value="LONGITUDINALS LACKING PROTEIN, ISOFORMS F_I_K_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2" id="KW-0221">Differentiation</keyword>
    <keyword evidence="3" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="6">
        <location>
            <begin position="31"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="56473" checksum="49ED9D6320B6FF34" modified="2019-05-08" version="1">MDGSQYCILWNNYHGSLVNTLSGLRREGDLVDVTVVCGDGNKVRAHQLILAACSTYFRDFLRDNPSKHPIVLLPMEIRYPELKAMVDFMYTGQVCVNQERLQAFIRGARYLRIKGLEDNADDSDMEDLAPDMENDKPPLGVSTGGVSVSVGSGGESGATTTVKGRRVKDHRYTQHVELGDSDENREKWEVVDRKPVILPRAQPPPPPGSGMRRRRRARSALRKRAMHLSNHIVCYEQRTDGSDGGHERSEPINKIRRLGSPGHFHDNDLDICTCTSRKIWSVRDTEALLRVWRETLTQVPPSYFIRSMALCKRVARRLQGRGIQKNWRQCQVKMKNLRREVRLYKESVGRNNSRKPSEVATACEKLLPDIEDIFNKEEEIRREWYQMRAEERLKAEGRLVDGEAAPADILAQVAVLADSDLCDEDTDAQECVAGDGLETEGEAGAFTEGEGFTEGEGGFEEEVDTHTHVVHTQDDTAVHHIVEDVTLQVVTKQEPQSGTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TM28</accession>
    <name>A0A423TM28_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit beta'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_003845</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cytoplasmic vesicle</location>
            <location evidence="1 12">COPI-coated vesicle membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="12">The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001515">
        <property type="protein sequence ID" value="ROT77505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TM28"/>
    <dbReference type="STRING" id="6689.A0A423TM28"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000001">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000008">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="5 13" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="11"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="138"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="181"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="13">
        <location>
            <begin position="225"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="15">
        <location>
            <begin position="319"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="16">
        <location>
            <begin position="595"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="926"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="942"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT77505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="993" mass="111144" checksum="030FD676B793AB0A" modified="2019-05-08" version="1">MPLRLDVKRKLTARSDRVKSVDLHPTEPWMLASLYNGNVHVWNIESQQLVKSFEVCDLPVRAARFVARKNWVVTGSDDMQVRVYNYNTLERAHQFEAHSDYVRCIAVHPTQPFILTCSDDMTIKLWNWDKKWSCQQVFEGHSHYVMQIVINPKDNNTFASASLDRTVKVWQLGSPQPNFTLEGHQRGVNCVDYYHGGDKPYLISGADDSLVKIWDYQNKTCVQTLEGHSQNVSSVSFHPELPIILTGSEDCTVRVWHANTYRLENTLNYGLDRVWCISALKGSNNVCFGYDEGSVMVKLGREEPAMSMDVSGKIVWARHSEIQQANLKAMGDAEIQDGERLPLAVKDLGACDIYPQTIAHNPNGRFVVVCGDGEYIIYTAMALRNKAFGPALEFVWALDSSEYAIRESNFNVKLFKNFKEKKSFKPDFGCEGIFGGYLLGCRSSSTGLAFYDWESQELVRRIEIQPRQVFWSENGDYVCIATDENYFILKYSTDAVTKARETKEGLTEDGIEDAFDLVGEVQEVVKTGKWVGDCFIYTNSVNRLNYYVGGEIVTIAHLDRTLYLLGYIPKDNRLYLGDKELNVVSYELLVSVLEYQTAVMRRDFNTADRVLPTIPPAHRTRVAHFLEKQGFKKQALAVSTDPEHRFDLALSLGELEVCHQLAVEAGSEHKWRLVADLAQQQGDLQTAQTCLLRAHDYPGLLLQATASGNAGLIKEVATEAESQGRNNVAFLSHFLTGNLKDCLELLIKTNRIPEAAFFARTYMPGEMSRVVGLWKTAAGEKIGQSLADPAQYDNLFPGLKDAVKSQQYLQQTTKPIPAASAASVPGNHERNIIEEMRAAEASGAFVYIAPEGEEVEFVDAPQQPEKGIDSLNEEVLITPSAPVMPVSMPVADAPEPLVPTPAAPPPAAVPTPELIDDDITKDVGQELREEVDAFSNPDEDDWGSKEKEERLEAAGSASSSTVPSRKMFDWDEDEAEDWGFQQSKGELGYKVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMT9</accession>
    <name>A0A423TMT9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001478">
        <property type="protein sequence ID" value="ROT77784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMT9"/>
    <dbReference type="STRING" id="6689.A0A423TMT9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="43603" checksum="BBD3083B537114E7" modified="2019-05-08" version="1">MHLPLLYSLPAFSLSSVFHFFLHLSFPILSLPTPSIRKLPLPPPHAHSPPLPPIPLPSYPLPSHPSPTPSPPPPYPIPSIPHPPFSLSSPHPTSSLSPFFLLPHPYLPSFTPTPLPPSPTPTFHPSPTPLPPSPTPYPSSPTPSPSLPTPTFHPHPPSLPPSLPYSIPPPPYLLPHHYFHPYPPPSLPSPYIPTPPTLSLLPSPLHPPPPSLPSLPTPYIPSLTHPLSSLPPSPTFHPSPTPSPSLPHPYIPSLTHPLSLLSSPYLPSLPHLSPSHPPPPTFHPYPPPLPPPPSPYIPSHTHPLSLLPHPLHSIPHPPSLSPPSSLPPIPHPPSLPPHPLSSPPPPPYFHPSPTPSHSRHPYIPSLPPSPSLPTFHPSPPLSPLPPLPAPSKSGVTQSMSLRESQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRJ8</accession>
    <name>A0A423TRJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative formimidoyltransferase-cyclodeaminase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001294">
        <property type="protein sequence ID" value="ROT79080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRJ8"/>
    <dbReference type="STRING" id="6689.A0A423TRJ8"/>
    <dbReference type="OrthoDB" id="48036at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005542">
        <property type="term" value="F:folic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.670">
        <property type="entry name" value="Formiminotransferase, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037070">
        <property type="entry name" value="Formiminotransferase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051623">
        <property type="entry name" value="FTCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12234:SF1">
        <property type="entry name" value="FORMIMINOTRANSFERASE N-TERMINAL SUBDOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12234">
        <property type="entry name" value="FORMIMINOTRANSFERASE-CYCLODEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="39258" checksum="854134AF0600E405" modified="2019-05-08" version="1">MNNSFFRPQVLPPSSLARPHSPTFPPRLLTIRDPAADACLPSFRTARHQHLPPESEGRGREAEASGVAERLTKTVPGSSFFLFGAGDPAGRGLVARRKEVGWFRRPVTYHALAHDLGSAPTERYGLTGVGAIPYMMNVNVTLDSADVALGRRVASALRATSPGGLPGVQSMAFPHEGRVEVACNVDLLPASEAPASHSMKASLGGRYFYTPPEQIEARVLEEAGGVGVVGTALSLPTSTSHPPFPSPSPPLPPLTSPSLPLLLPFPSPLPPLTSPSPSSPPLPPTPLPPSAARRKFLSLIPLAGEGIHGTDNVRGAEKTSVGRALQTPRAHAYLGTYCGRARTPSSLHVFHTRPHTPGLSSCYSSAVMGGAQGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT36</accession>
    <name>A0A423TT36_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_001691</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01001223">
        <property type="protein sequence ID" value="ROT79580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT36"/>
    <dbReference type="STRING" id="6689.A0A423TT36"/>
    <dbReference type="OrthoDB" id="10252502at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="565" mass="63956" checksum="9358F2F9FB03DBC7" modified="2019-05-08" version="1">MSTYTISEKVRNFAIYTRLVTLLLQIVSNLIIPDHQADAFVSPQDPEVKSTWGDEIVQFLLGGLVRWDAQYFLHIAQYGYTHENTLAFFPLFPLAVRYLAHVISIPLQFVCSHHSILLISAVLLNFYLFIKTAAVFHRLSLVVLKSEILAYRAALLFCINPASIFFTAPYSEGLFAFLTFSALLTNERRSTSVAALPFGLASAGRSNGLVNIGFILYRKLLDCSNYYYKIRNATTESGQLSLLIVVILTFNYTLIPLFIGCFLVVLPFVIFQTWCYFTYCHKDGTSSTLAPHLEMYVRANFLHSPVMGEAEWCDNTPPIAYSYVQDKYWEVGLLRYYEIRQVPNFMLALPVVMIVICHAALYMVDNPQVCWGLGIPQPVGDKPSSRRKQALTWPEEGINSWRVFVYTAHSLCLCAFCVLCIHVQAPSSPAFIHRPSLSVRGRRPWRLALPLPLSLRHSRPRPHLQGSVAAGLVPITWAREASRASRSDVNKGRSVFPTSTMTTSCATHDSIPVFPFKPGDERLQFLARREIGSEYIARCPVVPRARFGLWQRSPRRRHFLAVNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTT9</accession>
    <name>A0A423TTT9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative pancreatic triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001403</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001179">
        <property type="protein sequence ID" value="ROT79873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTT9"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016272">
        <property type="entry name" value="Lipase_LIPH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF185">
        <property type="entry name" value="LD47264P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000865">
        <property type="entry name" value="Lipoprotein_lipase_LIPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00821">
        <property type="entry name" value="TAGLIPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Lipase" evidence="8">
        <location>
            <begin position="45"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000865-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000865-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="48352" checksum="DFDBBB36439A96AC" modified="2019-05-08" version="1">MDAEDGDVTLEILPESGRGHRRLGEGSPAPLRPSGRQHQAGGRCYGYLLHVLAEFCDVNLRSVHLIGHSLGAHLMGYAGQYVKTIRDEQVGRITGLDPAGPYFTNTPPEVHLDPTDAAFVDIIHTDMPSEGWEISKLGHPEALGHVDFYPNGGSLQAGCQGSVHSHIENDRSVAEGVLSYIGCNHQRSHEYFTESVNSRCGFLGVVCESWEAYLNGSCWGCVEDQKEKRGRCLSMGFSATPLTLVPQPGTSHAAIPQPAGNENSDSSSDARASNSTEGERRANDSASETRAPHVTEVPATVPGFPVKVFLGTAGQKPFCAEQYRITVMTSEASAGSSDGDLARFTVGLHGRGGVHPLPAPESFSPPVGRVLSLRVFYEEDNGVLHSLIWRFSKPHLFVEAFVVEELSTGAVARFPFCGEKMEAGHSHTLYPDRQCPPTPLALEEEANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0D9</accession>
    <name>A0A423U0D9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000872">
        <property type="protein sequence ID" value="ROT82167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0D9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="765"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="850"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="891"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="996" mass="110484" checksum="0E113F32DCF8536B" modified="2019-05-08" version="1">MMRQLTSDRKTKVKEKPKTKREGDKEKKETKLKGKDDKEKGEAATKNKKTAKKRSNSTNKPKKKSEFLASENAGIKLLYIHQGEDTLPKDKEGKDKASKNRLGSSRREESRNGLLHRQQEKEARPRVLRTNVSKFGSSNSLSYESSPYSSPSPSSTPTRGHSERRDKRQQKYVIQGDSSDSSPTSTINRGRSRTGFYAFNDLHFSRSSFSSSDSSSLNKKGVVAGKKSPRPVSFSRTSEATKGKAKGPKDATTIPPSPLSPANYPPRIIYTESESSKPPAKNGLQKDKTRPKKDAKEKEDRSVSRWSGGDSGIDLFNLVGSAVSTVSSTASGSFMFDSTTSFSSFSPCCSPEQKSLGVIAIQNPIYEEQRSLKRSEIIKTANFGLNSAGNDQAEEVRVQIHHSENGGGDPQLQLAENRPRAKDFIFNHTSYTIQEEDQKEEEDGGDGNCTVLKQSSTELPPPPVSQPLKSTNPGSSSSLARVGSPQQKKDERPDSDSDAPPPPLPKNPPPPPSDVSFQDSRNTLESPVQDASCRTTPVSFPSKSHGQNTTEASQARVPAPQVAMLSDYEVNLRARDREPKVKFYMKGEGKIGDAHDAPVKNFEILILDDQYEVESSEENWILRQSPYNKMSPASSTASPPPQPPPKKAKKTKTGTLTRVKNSLENLLQNQSSKAKQEETANDSSKQKSEQNSLRKNKEEKENNTDIENGTFRLRGKDISRPFPLIRISPPDSHVEREHHEDTVSLSSESILPTWESYEISREIKKGNSFSDKHSQSTQDKHTNIEKGSNQPVENGYGSKMSNAATNKRLEKDSNFRRELPKESHYILETPAQMPKMPVRQVAQRDASKLLNDNLSKVNPNERPGRPLPNEGRRVNDLKKYFTCGINTCPKPRKGILKKGQEDGPSAPPVPQKTQRKNSVTYSLPPPPSPATAARQVEAEVDKVLRYEIEAKLRAKPPPLPPKGTARRTTIVKKRTVNLRVESFPLNTKPRSGLDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5B0</accession>
    <name>A0A423U5B0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative epithelial chloride channel protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022911</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000626">
        <property type="protein sequence ID" value="ROT83907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5B0"/>
    <dbReference type="STRING" id="6689.A0A423U5B0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019296641" evidence="2">
        <location>
            <begin position="20"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="3">
        <location>
            <begin position="24"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="782" mass="84593" checksum="69485C59A2C45DC2" modified="2019-05-08" version="1">MIKLAWAVTCLVVWAGVSQVSVGVRLENGRYEDVVLAVDPAMGTDVISITDLEKKVKTLLQATSDSLHAATEGRLSLGSVRVVLPQTWNAPDDLLEDPVEGVSWGSADIRLEEPEKDYRGNYVSHTPHTLQPGQCGVPGRHITIHTTLLDADYAEANYGSQGAVMAHEWAHFRWGVMEEHGFPGDGVFPVHYSRGGQDELPTSCFAGDLEGKFETEKGEACDPGAASPACYFLPSGSSTNGSLMYLTHLSESAAIISDLVKSKIQDLSRKFQSFAVGMATCRLVGENVELIKKREFSPVADVNSLDEFMPAVSDRESNKTVPLGRAVAQLVPTWTDHTPGTLLMALVYNHENPPEEEGQNAPPGRPQGTSRTPPWAAFCRRPAAAFTAPRTRPLIIIHLLEDFERYFSSSHLDDHICDIACGSEDAEKFNFFCGNFDGGIYASYKTTNIAGSDVGYEFKVSSTSQQSHAATVTWSTVEDIDNPMVHVDLWSSEDRGFKAVIPESAGLRLFCEVVHPQGYLEGLTIAAEVTINSVEPFVVTFVDEELGEIDTRRSDSIWTAIIPGDYPAGSELIVTKLAINHNPDIYSPLSTGNTVGAPDRPLGRPLLRQLPRGKTLQRSANQPETPPKVVGLEPAEQQVEEDMVKVAFKWGGAAETRTARTNPDSYMIRYSTDLYGLIDDFQSAKEPLEGTGTAPGSATEPVVSLPYAELVTREVYLSVAAERKGVVVSVAVAGTSGNCYCGNGTTGEATTTPPMTTTDSASANALCQLLFPAVVLAFLTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U697</accession>
    <name>A0A423U697_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_022577</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Recycling endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000578">
        <property type="protein sequence ID" value="ROT84236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U697"/>
    <dbReference type="STRING" id="6689.A0A423U697"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055038">
        <property type="term" value="C:recycling endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002090">
        <property type="entry name" value="NHE-6/7/9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF187">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01088">
        <property type="entry name" value="NAHEXCHNGR6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0967">Endosome</keyword>
    <keyword evidence="10 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="12 13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 13 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019134665" description="Sodium/hydrogen exchanger" evidence="16">
        <location>
            <begin position="26"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="17">
        <location>
            <begin position="59"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="525"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT84236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="639" mass="70215" checksum="FCA2B88096794405" modified="2019-05-08" version="1">MAGVGGEGPLFLALSSSFLLQSVNGKPSTGTDLEIDEKYQNTHRIDSLNILLYTFLLILTVVTIWIFKYRRARYLHETGLAVIYGLIVGAILRYSGDNTPVSHMVVDPKEPQTYHGDAPPDTLWLKYGGNINASQNRTYAYSFRGEIPESLEDEIVQKATFDPEIFFNILLPPIIFSAGYSLKRRHFFKNLGAIFTFAFLGTTISTFVVGGLVYGFLWLLSSSFSFIDCLLFGALISATDPVTVLAIFSDLHVDVNLYALVFGESVLNDAVAIVLSSAIESYGSASGGFETSAFFLAILNFLWIFSMSFLIGSVMGCLTAILTKFTRLKDFPLLETALFVLMSYSTFLMAEAADLTGIVAVLFCGICQAHYTYNNLSAESRVATKTLFELLNFLSENFIFSYIGVSMFTFDHHKWDVGFISIAFVAIIAGRFMCVYPLSFLLNLGRTPKIPINFMNMLFFSGLRGAIAFALAIRNTSSTARKAILTTTSLIVIVTVILCGGLTTQVLSWLGIPVDVEDDETHHLNTSFQPIRNGPGAEDGGEGPVEGTSSSSSKYEKAWLFRIWSQFDVRFMKPFLTNSRPTLLDTTPLCCAPLARLLTTTEQLTQNITNPLYDGDLGLGSSSSVPTRVSVAGSRGQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6F4</accession>
    <name>A0A423U6F4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000569">
        <property type="protein sequence ID" value="ROT84261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423U6F4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21698">
        <property type="entry name" value="PROTEIN (PUTATIVE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21698:SF4">
        <property type="entry name" value="PROTEIN (PUTATIVE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="524"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="640"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="685"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="788"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="863"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1880" mass="195267" checksum="FF784B33733FB9F6" modified="2019-05-08" version="1">MKARAKPDGATLQDRLLQHLPQCPPQCLPQFLPQCLPQYPPQCLRQSLLQCPPQYLPQCLPQCLPQCLHQCPLSDCLSAPLSAVPTSMTPSAPALVFPSAPFSVPHSVPASLFSSVFPSLSPQHLNSVPPSAPFSVPASVPFSFRAYLNDPLSACLNVSLSTFLSASLSTFLSACLSISLSAFLSTFLSACLSISLSTFLSASLSTFLSACLSISLSTFLSASLSAFLSASLSTFLSASLSTFLSASLSTFLSASLSACLSLPLSTFLSASLSTFLSASLSTFLRVSLSTFLIACLSVSLSTFLSASLSTFLRTSLCTFLSACLSASLSTFLGASFSTFLSVSLSTFASACLSVFHSTFLSASLSTFVSASLSTFVSASLSTSLSASLRTFLSTSLSIFLSASLSTFLSACLSVSLSNLLSACLSVSLSTFLSASLSVSLSASLSVSLSAFLSACHSVSLSTFLSAFLSVFLGTFLRASLSTFLSACVDEHLLSTFLSVSLCSFLSVSLSSFLSACLSVSLNTFLSASLSTFLSACLSVSLSTFLSASLNVSLSTFLSASVSTFLSTSFRASLRASLSVSLSTFLSASLSTFLSASFSACLIVSLSTLLSASLSACLSVSLSTFLSASLSTFLSACLSACLSACLCVALSTFLSASLSVSLSTFLSASFRASLSVSLGTFLSASLSTFLSASFSACLIVSLSTLLTATLSVSLSTFLSTSLSTFLSACLSVAHSTFLSASLSVSLSTSSAPFSVPPSAPSSMFPSAPSSVPALVTFLSACLSVSLSTFLSASLSISLSTFLSASISTFLSTSFRASLSVSLSTFLSASLSNILSACLSVSLSTFLSACLSVSLSTFLSASLSACLSVSLSTFLSASLSTFLSACLSVALSTFLSVSLSTFLSASVSTFLSACLTCLSAQHLPQCLPQCLPQHLPRCLPQYLPQCLPQHLPQCLPQCLTQCFPQYLPKCLPQHLPKCLPQHLPQCLPQHLPQCLPQHLPQCLPQCPPQYLPQCFSQCLPQCLPQCLPQCLPQCLPQCLPKFLSTFLSASLSTFLSASLSTFLSASLSTFLSASLSTSSVPPSVPPSTCLSASLSTFSVLPQHLPQCLPQCPPQCLPQCFPQHLPQCLPQCFPQHLPQCLPQHLQCLPHTFLSASLSTFLSASLSAPFSACLSVYLGAFLSASLSTFLSASLSTCLSTFLSASLSTFLSTSLSACLSAPLSACLSAPLSAFPQHLRQCLPQHLPQCLPQHLPQYLPQYLPQCLPQRPPQCFPSAPSSVPPSAPSSVPPSAPPSVPPSAPFSVLPSVLACVSLSTFLSACLSDILSTFLSASLSACLSASLSTSLSASLSSCLSACLSAPRCLPQCLPQCLTQCFPQYLPKCLPKCLLSTFLSASSAPSSVPPSAPSSVPASVPPQYLPQCFSQCLPQCLPQCLPQCLPQCLPQCFPQYLPKCLPQHLPKCLPQHLPQCLPQHLPQCLPQHLPQCLPQHLPQYLPRCPPQYLPQCLPQHLPQCLPQHLPQCLPQCPLSACLSVSLSTFLSACLSVSLSTFLSASLSTFSASLSACFSVSLSTFLSACLSAPLSTCLSVSLSACLSACLSVSLSTFLMPPQSASLSAPFSACLSVYLGAFLSASLSTFLSASLSTCLSTFLSASLSTFLSTSLSACLSAPLSACLSAPSVLSLSTFVSASLSTFRSASLSTFLSTSLSTCLSACLSAPLSAFPQHLRQCLPQHLLQCLPQHLPQCLPQHLSRCFPQCLHVFPSAPSSVPASVISSAPSSVLPQCLPSVLPQHLPQCFPQFLPQCLPQCPLGACLSACLSAPLSACLSALLSASLSAPLSTCLSTSLSAPLSACLSASLSTFLSASLSACLSAPLSASLSASPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U947</accession>
    <name>A0A423U947_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000373">
        <property type="protein sequence ID" value="ROT85222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="779"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="937"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1155"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1446"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1518"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1655" mass="202311" checksum="8EE43DE51F0C167D" modified="2019-05-08" version="1" fragment="single">QTQEQQTDTKNRQTPRTTDRHQEQTDTKDRQISRTDRHQEQTDTKNRQTPKNRTDTKNRQTPEQADSRTDRHQEQADNQNRQIKNRQTPRTDRHQEQADTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQADIKNRQTPRNRQTRKQTDIKNNRHQEQTDTKNRQTPEQADTKNSRHQTDRHQEQADTKNRQTPRTDRHQNRQTPRTADTKQTDTKNRQTPRTQTPRTDRHQEQTDTKNRQTPRTGRHQEQTDTKNRQTPRNRQTPRTDRHQEQTDTKNRQTPRTVDTKNRQTPRTDRHQEQTDTKNNRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTSEQTDIKNRQTPRTDRHQEQTDTKNRQTPRTANTRTATPRTDRHQETDRHQEQTDTKNSRHQEQTDTKNRQTQEQTDIKNSRHQEQTDTKNNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQQTPRNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQADTKNRQTPRKDRYQEQTDTKNRQTPRTDRHQEQTDIKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTSRTDRHQEQTDTKNRQTSRTTDTKTDRHQEQTDAKKNRQTPRTDRHQEQTDIKNRQTPRTDRHQEQTDIKNKQTPRTDRHQEQTDAKKNRQTPRTDRHQEQTDTKNRQHQEQADTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDIKNRQTPRTDRHQEQTDTKNRQTSKQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDAKNRQTPRTDRHQEQTDTKNRQTQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNSRHQEQTDTKNRQTPRTDRHQEQQTPRTADTKNRQTPRTGRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTSRTDRHQEQTDTKNRQTPKQTDTKNSRHQETDRHQEQTDAKNRQTSRTDRHQEQTDTKNRQTPRTDRHQEQTDTKTGRHQEQQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDIKNRQTPRTDRHQEQTDTRTDRHRTDRHQEQPTPRNRQTPRTDRHQEQTDTKNRQTPRTADTKNSRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTSRTDRHQEQTDIRTDRHQEQTDTKNRQTPRTDRHQEQTDTRTDRHKNRQTPRTDRHQEQTDTKNSRHQEQTDTKNRQTSRTTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTSRTDRHQEQTDTKNRQTSRTDRHQEQTDTKNRQTPRERQTPRTDRHQEQTDIKNRQTPRTDRHQEQTDIKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNSRNTKNRQTPRRTDRHQEQTDTKNRQTSRTDRHQEQTDTKNRQTSRTDRHQEQTDTKNRQTPRTDRHQEQTDTKNRQTPRTGRHQEQADTKNRQTPRTDRHQEQTDTKNRQTPRTDRHQEQTDIKNRQTPRTDRHQEQIDTKNRQTSRTDRHQEQTDAKSRQTSRTDRHQEQTDTKNRQTPRTDRRQEQTDIKDRQTPRTDRHQEQTDTKNRQTPRTDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB24</accession>
    <name>A0A423UB24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000156">
        <property type="protein sequence ID" value="ROT85900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB24"/>
    <dbReference type="OrthoDB" id="200110at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029090">
        <property type="entry name" value="DUF4659"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33663">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33663:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="22552" checksum="A21EFD9ECC1A5C4A" modified="2019-05-08" version="1" fragment="single">MTTAKKRVNIACLRKSNRELSCLWSPRISPGCQGPLLRTPPRRLGAQSGRVFKKVQEDRATFAPFVTDRRFLRVIFHSHHIAILTIHHHFIILTPATLIENCHITILTHVALSHSRSEVTMKDPGVKLDLYNYDLPQYESCPYILTSPRSLEACKRLGIKPVELLQKSREEFQAAHPEMSLEEALVAFHRQERNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXK0</accession>
    <name>A0A3R7LXK0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pachytene checkpoint protein 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016114</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003017">
        <property type="protein sequence ID" value="ROT65916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXK0"/>
    <dbReference type="STRING" id="6689.A0A3R7LXK0"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048477">
        <property type="term" value="P:oogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19508">
        <property type="entry name" value="RecA-like_Pch2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000662">
        <property type="entry name" value="Pachytene checkpoint protein 2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23563">
        <property type="entry name" value="TRIP13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0221">Differentiation</keyword>
    <keyword evidence="8" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0896">Oogenesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0744">Spermatogenesis</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="161"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="416"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="55752" checksum="08A7590198B19780" modified="2019-04-10" version="1">MAQNTSLEKPILHVEILQRRRSVMAKDVLMHEVDTILKNMGKTYVDSHIKEFPNSGLQEHILHIKICEVQDNADVKEVELCNVMPRYYVYQLECDGPGIEELNEGEEEIPAATYWILPAAEFDNYWENLVFDTNIKEELLNYIRTTLLFSDRKICESIISWNKVVLLHGPPGTGKTTLSKALAQKLSIRLEPRYKYAQLVEINSHSLFSKWFSESGKLVQKMFTKITEMVEDPQSLVLVLIDEVESLTCSRASCSNGTEPSDAVRVVNAVLTQLDQLKKYPNCLILTTSNITGTIDLAFVDRADIKQYLGLPSKGAIYQIYHSCIIELERTGIIVDSERLFTLKELTLIKMAESKVTQPSLLLMKIAEQSQGLSGRTLRKIPFLAHALYIHAPRVSLYDFLFAMEKAVQKQLKDREKISQPSPQLLPYSNLIPTPHPQFRTHPPPMPLSPNNHRPPLPSRTVHPFPIPTPISFYSPPPPIPNLTPPPAISPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXQ9</accession>
    <name>A0A3R7LXQ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002820">
        <property type="protein sequence ID" value="ROT67353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXQ9"/>
    <dbReference type="STRING" id="6689.A0A3R7LXQ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="45931" checksum="4133211439E0FC29" modified="2019-04-10" version="1">MADRELDGARKKRGTEMTSEALLKTPTKSQSRFTKPPLRCAAASPPPLGRCVAPPSAAASNRCVAPPSAAASAAASPPPSAAATSPPPSRCVSAAASTSRPLRRPPPRPPSPPSPLQCVPPPLGRCVAPPPSAAASPPPSAAANRPPLGRCVAPPRPLHRPPLRCIAPPPSAAASPPPLHLGRCVAPPRPLPPPPRPLRRPPPRPLRRPPPCRCALGPPPLGRCVAPPSAAATPPLGRCVAPPPAASPPRRCVAPPPSATASLRCVAPPLGRCVGPLLAPPLGRCVAPPPTPLGRCVPLGTAVVSPRCRSASPPPRPGRCVAPPPSPLRRPPPSPLRRPPPRPLHRPPPRPLRRCAPPSATASPQPPPPLGRCVAPPPRPLRRPAPPPPLRRPPSAAASAAASPPPSAAASPPPPRPLQPKSSAPSWRRVLFPVPFNTKIFTTEYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M158</accession>
    <name>A0A3R7M158_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002482">
        <property type="protein sequence ID" value="ROT70034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M158"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1010">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1480.30">
        <property type="entry name" value="Designed four-helix bundle protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="454" mass="53970" checksum="E459946851FEB4F9" modified="2019-04-10" version="1">MRSTDIGRDIVDKISEEVNKISDEVDKISEEVDKISEEVDKISEVDDKISERSDKISDEVDKISDEVDEYRGEVDIGRGRQISEEVDKISEEVDIDEVNKISDDIGRGRQDIGRGRQSTKSTRYQVDKISEEVDKISERSTRYRTRSTRYRKISDEVDKISDEVDKDEVDKISDEVNKISEEVKKISDEVDKISEEVNKISTRYRKRSKIYQVDKISDEVDKISDEVNKISDEVNKISEEVDKISERVTRYRKRSTRYRKSRRYRKRDKISEEVDIYRKRSTRYRTDTRSTYRKRVDKISDEVNKISEEVDKISEEVDKISEEVDKISTESQQDIGRGLTRYRTRSTRYRSQRSEESTRLSERSTRYRDVNKISDESTRISTNKISKRSSTRYRKRLTRRSKRSTRYRNEVDKIIGKEFEVKISDKIWSTRYRRRSDYRGQQDIGRGRQDIGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1P5</accession>
    <name>A0A3R7M1P5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_017236</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1P5"/>
    <dbReference type="STRING" id="6689.A0A3R7M1P5"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050321">
        <property type="term" value="F:tau-protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14337">
        <property type="entry name" value="UBA_MARK_Par1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000156">
        <property type="entry name" value="Serine/threonine-protein kinase SIK3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="256"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="300"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT64828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="50769" checksum="863C9F0C5B57992C" modified="2019-04-10" version="1">MLMDDALSNCLRVAIKIIDKTQLNPGSLQKLFREVRIMKILDHPNIVKLFQVIETERTLYLVMEYASGGEVFDYLVFHGRMKEKEARAKFRQIVSAVQYCHQKKIIHRDLKAENLLLDSEMVIKIADFGFSNEFTPGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPARRASLETIMKDRWMNIGYEDDELKPYVEPTIDLDDIKRIEILSEMGYSRAEIEDSLKSQKYDDVYATYLLLGRRSSDLESDGSRSGSSLSLRNTCLTPRGQESSGAAQSPSHSHRGVHRSVSATNSKPSRRASSGGETILSHSVTILLPNCSISAFHPHPLPSFPAPILTNLIHWPAHALCSASSAWEARIDILVTTLTQHNCPPGMLDTALRLERKKGLYTLTLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M246</accession>
    <name>A0A3R7M246_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002528">
        <property type="protein sequence ID" value="ROT69705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M246"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="412" mass="44667" checksum="8CC73D2040982122" modified="2019-04-10" version="1">MSEPSFPACCRSTRQAAIRRQDRSCVSSASPTRRLRKSPTIHRIVMYHVKGESKDTNYVRRQLGTDAEGRGLHFRQSPWRSASSPALKQQHVYGSNRLFRFIIISPSASTSTASPFSSSLSHSAPPSPPTPLQSSSARQEDQEVTLVSPASMADATSDAINNANEKGTLTIPGHAEVEALLQAAVLASVAVDPIHHAVLLARALVVDDGGLGPPEEALAALARDDTIVDAGGLVAAHLAGNDLNLGCGRRARARSLVLESRREGRRGRGRKSRTSHYHSPLPPPPPLLPTHTFQRPLHRLARLLQPFHITRTSHSSIGFLASSRPSRVTPIAALKQYLVTRPTRISFPIQQSALILRSYNFTRPVSPCDVIIELRATLGSAMTSPLTRTNQSQVSQASRAMNPASHLLRLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M256</accession>
    <name>A0A3R7M256_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002525">
        <property type="protein sequence ID" value="ROT69720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M256"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="528" mass="56043" checksum="19B9C0E96D6F9D54" modified="2019-04-10" version="1">MTLPPILLPFFPTTLLLSFFLLPMTLPPILLPFFPTTLNPILLPFFPTTLPPILPGHAPFLSQATPSALPSAFSRLPSSLFSSSNCLPFCPLFFFLSISFSSFSSLLFPFSLLSSPFSLLPSPSVSLSSFSPLPSPSTSLSPFSPLPLPSPIPSPSIFFLSSSLSLSLLSPSPSLLSPLPPSPLLPSLLSPLPPSPSLPSLLSPLLSFLSPLPPPPFLPSLLSLLPPSPFLFLSSLLSPFSSSLSLYLPFSPLPFPSISLSSFSPLSFPFSPLPSPTISLSPPSPSPPSPFSLLSSPLSLHLPFLFLSSLLSLLSSSLSLYLPFSPLPSPSISLSLLFPLLLSPFLSSSLSLYLPFSPLPSPSISLSLLFPLPLSPFLSSSHSLYLPFSPLPSPSISLSLLFPLPSPSPSFISFLPFPNPSPSSLSHLLPLFPPSLIPPHLPFPLSLHLPFSLLFPPLSHLPPSPFLPSLPSPSSLSPLPPPPFLASLLSPFPSPSTSLSPISRLPFPISFFYCPPPLPSLLSLPLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2N2</accession>
    <name>A0A3R7M2N2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002466">
        <property type="protein sequence ID" value="ROT70116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2N2"/>
    <dbReference type="OrthoDB" id="6338307at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="219" mass="23388" checksum="AC0E35C7D8D168A6" modified="2019-04-10" version="1">MVRELTGQSTVPSDVKMLRIVSLAVTLAVCVARPNQWDDQLGLFPADGGDSQPILPRAVANPTTPNQILDAVLEGAIAYMEALGWCGSKNVQNGESNLPFQVNSDGSSSENFSITKANVTGLCSLRRSKSASFNADQSVLSGSVVVENARANADYTNIASYTARSGHDLLESASNLDGNNMKDVHSAGFRKALREILEKTMASNVKVQINKSIQDMKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5T1</accession>
    <name>A0A3R7M5T1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002003">
        <property type="protein sequence ID" value="ROT73696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5T1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="417" mass="45118" checksum="58F7292982B14BDF" modified="2019-04-10" version="1">MVNIPGDAEQSDTVTLEDFTDEFDERHGIGDFGYSCDDFDIFPSVSMDVCAVETPAGEGIIPKGNLEHLGSDADEDTAQELRENLRGARLTAKEAARRAQQGWARDYNRRVRQRFEPAVGDLVLLRNFSRPGGPARALGPRWSKPARIVKRIGPVNYMVSSLLIFINISFSVPLSFPLTFFHLHPPAFPSSLAVPTSLFLFPLSIPIFPFSLYTPFSPLPPSLPSSPLHPFPSPSFLSHPLHPCYSLPSIPLQPRYSLLSSTSSSSPLHPFPPPLSLPPTLLSPSPSSLHPSSPSPTPLLLLLSSPPSSPPTPLLLPPLLSLPLLLPHYTPIPPSSPPIPLLFLLSSSSLSPTTLSLLLLPPSLSPLHPFPSSPLHPHPYPSSTPPKPLPIPPPSPRNPLPSPLPPAPHLFQPIISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8Z4</accession>
    <name>A0A3R7M8Z4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001678">
        <property type="protein sequence ID" value="ROT76232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8Z4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="647"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="787"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="858" mass="94096" checksum="65BE1A46771CC698" modified="2019-04-10" version="1">MYLHQFISRSELLVGSSTYFPRKELLVGIFPPLSTSFPREGSSRRIVHLFSPEGAPRRDLLPPLSTSFPRKELLVGIFHSFHLFSEELLRRDLLPPLSPLFPERTPSGISTSFHLFFPAELLVGIFYRLFPPLFPGRSLLFRPSSLFSPEGALVGISPRKELLSGFPPLSPRKEAPRGDLPRLSFSPEGSFLVGIFTSFHLFSRKELLVGISPPLSPLFPEGAPRRDSSTSFPGKELSGGILLTPLFHLFSRKELLVGNLPPLSTSFPRKELLVGIFPPLPPLFPRKELLVGDLHSFPPLFPGRSFLVGIFHLFLHFFPPEGAPRRDLSASFHLFSRKGPRRIFHLFHLFSPEGAPRRDLPPLHLFSPEGAPRRDLPPLPPLFPGRSSSSGSSTSFHSFPGRSSSSGSSTLSTSLSPKELLVGISHLFSPEGLLLPPLFFFPGKELLVGIFHLFPPLFPGRSSSSGSSTSFHLFSPEGAPRRDLLPPLSTSFPRKELLVGIFHLFSPEGAPRRDLPPLSTSFPRKELLVGIFYLFSFPGRSSLFHLFSPEGAPRRDLPPLFLPLFPRKELLVGSSTSFPRKELLVGIFHSSTSFPRTPRRDFYREGALVFSLFHLFSPEGAPRRDLHLFHLFSPEGAPRRDLPPLFPGRSSSSGSSTFFRKSSSSGSSTFFPGRSSSSGSSTSFPRPRRLAQGFQSASKSTESKRGIGESPPPPPLTSSPSFPNSSTLLPPPLHPPSPTSSTLLPPSPPPPSPTSSTLLPQPPPCHSSENRPKTPSALRTVPPPSSPGTAHPSTSNPTLSKNPHPTPKEPPPPLKPPHPTLKAPTPPQEPHPTSKEPLPTLENPPPKPHPTPKKKTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9H3</accession>
    <name>A0A3R7M9H3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001628">
        <property type="protein sequence ID" value="ROT76637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9H3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="39799" checksum="1E1AE375AD359042" modified="2019-04-10" version="1">MIFSFSNPFTTSYPPHPTTHFTSSLYLLPRPQPPPFSDPSLRPPHPPVPSTLPLPLPFYPPLLSSTLTLLSIPTILFSFPAHSHPPPPPPPPTPAFSYPFPTSYPHHPTTPLLPSSPLPLPPSTPHHSLTPSLRPPHTHLFLYPHLPFLRPPYATCSSTPPSPPLHPPLRPHTLFLHSTPPLPRAPSSAPTPPPPPASPPPHPSPPLRPLLCALNPPPPRPHPAIILAPPSLRPSSAPPPPPPPPSPPPIILAPPSPAPSSAPHPPPPPPHPRPSSSPLPPLRPLLCAPPRPHPPSPRPSSSPLPSLAPPPLRPHPRPHPRPHPAHHPRPSPPLRPLLCAPTRPTPAHHPRLSSHVTSICLYGHARSSLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCM8</accession>
    <name>A0A3R7MCM8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001292">
        <property type="protein sequence ID" value="ROT79087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCM8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="521" mass="58361" checksum="E0F051A9AB234DB4" modified="2019-04-10" version="1">MYTPYAPHTYRPSPPTNVLAPPPLLTHTHTPSPSSANVYIHPPSPLYTHPPPPPTNVYPPSHTTSLPQPNKYMHPPLHTYTPPSPPRNVYTPPLYTHTPPSSCATRIYTPTPHPQTQYTPPLTHTSSLLPHRTKVYTTPPYRTHTPSLLLQCKRIYTPHSTPTNVYTALLPPLHTHTTLPLPTHKRYIHPPHSSTVSLSLPPQTKYASLLPTYNPPHLSTHIRAPARPLQCYTPHSTPTQRIYILLSHLSPPHPPTSTYKRIYHPSSTHSYSSSRPPPAKKARPSLPPSIQTNIPLVLPHPQRRLSPSTTFTGTHLPPQPTKRNIHRPPRSTDHTLTLPYPQTYITPPLPLQHTTFPRSPSIANTPYTPPRRHQHKRNIHRHCLSKQQHVRSLPQRAQTYIYTPTPSTHTPSPVPPPLATYTPPYLGCFFPRPARSPPFATLPTHALCFSPPTPPNKTTHAHRLSASTVCALRPLPTPLSDRDEKTRDIILPCITAFISSWCTQALALGCGLPNKHHIQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHF1</accession>
    <name>A0A3R7MHF1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024985</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000910">
        <property type="protein sequence ID" value="ROT81852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHF1"/>
    <dbReference type="STRING" id="6689.A0A3R7MHF1"/>
    <dbReference type="OrthoDB" id="19174at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070531">
        <property type="term" value="C:BRCA1-A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031436">
        <property type="term" value="C:BRCA1-BARD1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.730">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="84"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="428"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="429"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT81852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="497" mass="54973" checksum="09AF4E2B25BA8233" modified="2019-04-10" version="1">MAEMLLAKGADANAKDEAGYSPLHLAALEGHESTAETLIDNGADVNAKEANGYTPLHLAGQAGQAATVEALIGKGADVHAKDDAGHTPLHMAAEEGHVAVVEALTAKGAYVNVKDEMGWTPLHWSAQNGHEAAVKALIEKGAKMNGTNQDGQTAMHIAASEGQLHVLFTLVKLGAATKVKNGRGKTPKELLKGTSTAANCDMEIFKDISLIEIMEKYLAAERGKASLLKENRVMQNDHKGELRSIKENQRKRDDSSRKIKKEVGALKGQIKAIQEEHKLELRYATEDIQEKDAEILKMKNEMIIKDERIMSLEAKPHEEMEDGTEEPREGESEVASENTMMNSNVAVLQDTIKLIQEQNTKELLSLRNAQHLKEAEAASQLREAQEALKSRNKRVKTLKRQMQEKETANEQCNSELKGKENQISQLEGQLEKKESKIKTLRSRLKERDDQIKKLEESLEALKKEPTVSPEEESEDESESYESSQAESEDEPPKQKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHG6</accession>
    <name>A0A3R7MHG6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Myosin-I heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004753</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001624">
        <property type="protein sequence ID" value="ROT76663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHG6"/>
    <dbReference type="STRING" id="6689.A0A3R7MHG6"/>
    <dbReference type="OrthoDB" id="312459at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF561">
        <property type="entry name" value="MIP31562P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="7">
        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="44323" checksum="8E6A80E00732C50F" modified="2019-04-10" version="1">MSCIDIFACDHCKVINAMLRHAGLPPEQSRITFQGPEERNYHVFYQLVAAAQNNKKSQTSSICGQRVSTLPESVWVHHIDGVDDVKRFDGLRLAFNVLHVPPEICDGIFGTLAAILWLGNLEFVDIDGEKCELSTSDKEVLTIVAELLNLEEEDLLASFFSARLTSRGNITRIPLKLAEARENRHAMAKALYSRTFAWLVDHINKCTNPGQDQTRFLGVLDIFGFENFATNSFEQLCINYTNEKLHKFFNHYVFALEQEIYRQEEIKFSHITFTDNTECLELLEKPPRCILKLLSEECRMPKGADKSYLTKLHQEFDSHPNYIKGEDRKKVGGGIWYQPLCRYVRCIKPNKSKSADSYDELMVLDQLRYLGMNDIIRIRKEGSLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHP6</accession>
    <name>A0A3R7MHP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heat shock protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000893">
        <property type="protein sequence ID" value="ROT82036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHP6"/>
    <dbReference type="OrthoDB" id="6350208at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="485" mass="53685" checksum="4B6627407104E54B" modified="2019-04-10" version="1">MSLLQSFASGQPVSESGVKCCNCGGVRRPWDMFLPITHRGSFFQDSFFSNLHQHFHATVRDILNRWCDSDLKLTDPWDDVNARHTDILDRYRQLRSRNLKEENQAVAVTSDDTSRKESEAQHKTTIIPIQMEETQDKKVSEGTSSESFKCEQCSQTQTSVNGGKQGVSVPIKNYDQPSEANKSQPKQTQITQESVPSSSSSRLIPIEIEANEANVNASANTARLSQTPSSDFQLKSSENDKMFHMDPFPGHFFPITRRGLFFSDSFFQDSWNDFQKAVREVLARWGDQSSLLDDLTSYRNLRSRDLREDTQAVTSSEDEHQHKHSTLQIEEVFSPISIDGSEKKLTSPGATKDNSHAALQNSQGSPMAPWTKSPGATAAPTCQQTSTNQTSNPLNKEDPYVLVTAVPARVEAVPDSAETPKPSSSSAPSKSASVKPKAFDRKGREGSEEEEKVDYKAALKPRTAGGKFPIKISGTVIGSDSAKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIH0</accession>
    <name>A0A3R7MIH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CUB-serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_024247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000801">
        <property type="protein sequence ID" value="ROT82585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIH0"/>
    <dbReference type="OrthoDB" id="414661at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018625554" evidence="4">
        <location>
            <begin position="18"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="34"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="156"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="379"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT82585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="606" mass="64420" checksum="BC25DFEEFDF3D125" modified="2019-04-10" version="1">MRSLLLLAAVAFQAALASPMGAPLLPETRAALLCGNYSINPDQSLFIKSKRFAQDYPKNHDCSYTFHCTDYAASLLLNCTRFELQGGDCTKDFMHVYDENSVDDRYCGTDGPQNVVTGDNFLGVRFKTNGDSVRKSGFFCKVSGCRCGVAQRSSRIVGGAETEVGEYPWQVGLYTTRLQTPYCGGSLVNNLYVVTAADCVDDGAEFQIILGEHDYTKVSRVYVRTPDQVSIHPGYNAQTKDNNIAVVRLSSPINLNADIPVKPVCLPEPSADFSGRTAVATGWGLMAEGGLESPVLREVELTVLSEADCPAGSSATLCAGEPEGGKGTCNGDFGGPLLVDVGGQYVLAGVTSHGTGCARAGQPGVYTDVSSVLDWMLPIIESDGKSWTDHINNNPWTVAILSKSSGQQVCSGAVINTYNVLTAKDCATGAVADLQVKANAQDLTSEVTRIVNRDVASVSSSGDLAILKLTTPLSLTNWEGIKPACMPAYNPDFTNTPAVQSGYGRLSAGAADSAQLKKVDGAFIWCSGLASNRVCFQPFQEQGFCGADKGGPIVAERDGRQYLAGIALKDNGCTTSSGMLFQEAARVASYYQWVMDSSQDGRFCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJE5</accession>
    <name>A0A3R7MJE5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Neural-cadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_022547</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000568">
        <property type="protein sequence ID" value="ROT84280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJE5"/>
    <dbReference type="STRING" id="6689.A0A3R7MJE5"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF438">
        <property type="entry name" value="CADHERIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="29"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="97"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="6">
        <location>
            <begin position="224"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT84280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="46423" checksum="AE10297A5D8C17D6" modified="2019-04-10" version="1">MKIVNQFDGLNQLGPPQVVERSGWGWEHFGVRAEGAVGHLHARKTLDYEDETHRRGFKFMVQVTDRGRGGWEDARHTDTAWVSVKLRDLNDNPPAFSRSHAHVTVQEDAAPGTVLAALTAQDPDMSPARPIKVSFFHARRHDAGANACTDGQEGVEYHVESAWDSLNVNADGEVRLWRRLDREAPGGAEGVARIIAVDHGRPPLSATATLTITVTDVNDCPPRLLPPTVVHVTESSPPTRLATLAATDLDVWEMGHGPPFNFSLAPSNPAHVKALIKLKFRQNLDSGRGGAEVWTTGSLDREEYRRLDVQVWLADAGGMSTTEVLTVVVDDINDNLMRPASKNVYLCKPRTYRILAVRAASTGAGGRCPLPCVWAVRRRNAGGVVVLRYRSLDGDRRCPCSGALRPRAHGWRGRCGGLSATPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJN1</accession>
    <name>A0A3R7MJN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002768</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001370">
        <property type="protein sequence ID" value="ROT78513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJN1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="258" mass="28350" checksum="6A34D53709CC9CCD" modified="2019-04-10" version="1">MVVLLIPPHLRPQHSPHNSQTTGHTLPLLHKASRRDKLLTQHPLHTVPHLHKVGTDIRRQLRLQFSQHQVVEGTAVMNKTVPTALEAMDRHLQALHMVVNPMLTSQLLLPKEILEDRRQHKEAMAEALHLEEVMVVHHLLGGGQGGGYNSGLGMAPPPLSAPPGCGGMYGSPLKQSPAPIPSCIVPTELLMSKVLLTGEIKGEVITKSPGSAQESFSEVMSQRIASDVTVCHQTKSNFNAAQGHLVLNYNFRELYRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKT6</accession>
    <name>A0A3R7MKT6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Cytochrome b-c1 complex subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_001895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits. The complex is composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein UQCRFS1, 2 core protein subunits UQCRC1/QCR1 and UQCRC2/QCR2, and 6 low-molecular weight protein subunits UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and subunit 9, the cleavage product of Rieske protein UQCRFS1. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and cytochrome c oxidase (complex IV, CIV), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001252">
        <property type="protein sequence ID" value="ROT79376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKT6"/>
    <dbReference type="SMR" id="A0A3R7MKT6"/>
    <dbReference type="STRING" id="6689.A0A3R7MKT6"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1090.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000022">
        <property type="entry name" value="Bc1_14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT79376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="116" mass="13978" checksum="7E4E4A4EA7F44D5C" modified="2019-04-10" version="1">MAAAATKSVGFLGQLSNSMKRFVFRMSGYNQYGLFHDDCLYENDDVKEALRRLPQNLKDDRHYRMHRAIHLSMTKTVLPKDEWFSYEEDHTKGRYLQPYLQEVITERKEREEWNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMH5</accession>
    <name>A0A3R7MMH5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">snRNA-activating protein complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001064">
        <property type="protein sequence ID" value="ROT80817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMH5"/>
    <dbReference type="STRING" id="6689.A0A3R7MMH5"/>
    <dbReference type="OrthoDB" id="6367122at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="337"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="48726" checksum="34004D02A5919F7C" modified="2019-04-10" version="1">MEVDDSDYENELGPVPESELQKQVDVAKIVDRAFEHVKHNQAAEEVADIIAGTEGLCSLEGVAVQDPLPPEIQARNFRVSHTSSGVGSDGTGSRSIHLRYSGTASFEVQNFAASGETVDDLLNASPSLETLHKLNSTLQKRFEEKLVKLERILQTNLARQAQLKDEISQDKANLEQEKKGDAREKAPFRVSNFCVPYFKNRSGMNAPKNEDAKFKLDNGCLDLYTTRARQWKAKEKEALKESVHKEWKQQLIGSKELKLRELQRKLRNAADPNSAETILEEMTEDLERQIRNLQSTPAESLTPPPHAKMDWEKIAAQAFDGHRTSDECSLQWENLLHPSINTSDWDPKEDMIIQELVTSSKHDVPDWNKIASKLMTQRTGYLFRTLVSFLMKWKAGKCTAVMPPTSRTERKTMLGHTCSLPSFTEGYGKSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MU79</accession>
    <name>A0A3R7MU79_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative peroxisomal membrane protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_023984</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000077">
        <property type="protein sequence ID" value="ROT85999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MU79"/>
    <dbReference type="STRING" id="6689.A0A3R7MU79"/>
    <dbReference type="OrthoDB" id="860at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="20985" checksum="E99A8C1E6016E33D" modified="2019-04-10" version="1">MLAAVILDKGIRSYNGCLFTRPLLTKACTSACTAALGDFLGQLITKQPKTNLISMARYASFGFVVTGPLAHYFYKMLDKIVPPTAYGAALKRLLVDRFTFAPLVLLLSLYILSRLEGKSHETCAKEVKAKYWAALKMNWKVWTPVQYININYIPQQYRSLFANLVAVFWIMYLTNKRRQATAKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MW35</accession>
    <name>A0A3R7MW35_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative synaptotagmin-4-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002339">
        <property type="protein sequence ID" value="ROT71134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MW35"/>
    <dbReference type="STRING" id="6689.A0A3R7MW35"/>
    <dbReference type="OrthoDB" id="5915960at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048791">
        <property type="term" value="P:calcium ion-regulated exocytosis of neurotransmitter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF351">
        <property type="entry name" value="SYNAPTOTAGMIN-4-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="138"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="285"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="48487" checksum="625B5EEA0F924855" modified="2019-04-10" version="1">MPEATSSTMWAVVGASLSVAVLIAVVAVWAMQRFRHRLRAGKQMEGLRLVISKSPYDPGQQVLVPTQVGWRRDSVADGMLAHPRTQRPQPLTSPQVESASRRVEELKASKKFSSTTSLNIDIYDEEATQENSQADFNVKRNPYVEFTLLWVSSNSTFTVYVLRLTNLPPKYVGCSCSVIVRLVRPKVTVSKTSIRLQNVGLNPEYSQVFTFPDVSLQDLQLSDLKFEVIARRSGHLLNKPVAELLVPVSKVNLVADKPVTALEPLCLRKKDSAYSTNGRRPSDANWGEIQVLAQYKETGSSQGRVKIVVLKAQSTVVGAKNSGEYHVEVIMRRGEETLVVNTTKAALGLKPVWNAPFIFDVSQEKINEHWIELNLIRLGWTKRKVTLGQAFLGLGTTPRGSQHWQSIAECPGREQLSQCYRNFTPKNRPSNFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MXP5</accession>
    <name>A0A3R7MXP5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002197">
        <property type="protein sequence ID" value="ROT72162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MXP5"/>
    <dbReference type="OrthoDB" id="6350022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018683624" evidence="1">
        <location>
            <begin position="33"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="50641" checksum="579B177C83C392B8" modified="2019-04-10" version="1">MPKLSPRFDGPYRVLQMRTLLHLLSLLHLSAASLPANYLPRPGAILEDIGTISFVSSYVEITISLDVLSSFYNTASTHLSLITQYRHAISTDTSLTPPQVSSLLSFLSLSQADLTPFKDRLPRPHPRRQRRGLFNFMGDITSYLFGVATHDELDARFGDYERALSSVAGKFKATFGAIHTISDTVNSLNNVTRQLSIYTDTNAQLIAREQHFTLLLAHVSLYQSRVRLFVDHLNTLTHDLILAVHGSVMPSLIPPSTLDSFIRRISAETRVHSFPLPLNGSFYGLSPDHDVILRSLDHTSLSFISSSALSSCSSVLSRFHACFDVFPPEHSYFHSSCHKALLSNGDVQSSCLFNQLNSTNPFLLTLPDLHLLYFFSATHVSISCGSNHADREVSAAFLLPRSCQLSARLISLRSSHSFPFRLLADYSHTPHNVPRPPCHQCLAPFSQRQEATLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NBA2</accession>
    <name>A0A3R7NBA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative solute carrier family 23 member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024384</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000822">
        <property type="protein sequence ID" value="ROT82425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NBA2"/>
    <dbReference type="STRING" id="6689.A0A3R7NBA2"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11119">
        <property type="entry name" value="XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="307" mass="33482" checksum="EB642FB0CEC27F93" modified="2019-04-10" version="1">MADNPTFEIEEGATLPQKENGATLPQKENGVIQPQLDAEAPPPPPSPSPEEEAKDALTSELLYTVDDVPPWYMCIFLGLQHYLTMVGATITIPFLLTPLMCIDDNDPARGKLVSTIIFVSGIVTLLQATFGVRLPIIQGGTFSFLVPTIAILTTTFEACRDLPLATMTEEEREEVWQQRMREIQGAIAVSAIFQVLVGFTGIIGILLTWITPLAIAPTVALVGLSLFEVAADKASLHWGVSFMTMALLILFSQYLRNVGVPVPTYSKDKGVSFSSVYIFKLFPRRLVGEQQGTDGPHHGPARQLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NFX2</accession>
    <name>A0A3R7NFX2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative serine/arginine repetitive matrix protein 2 isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000010">
        <property type="protein sequence ID" value="ROT86092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NFX2"/>
    <dbReference type="STRING" id="6689.A0A3R7NFX2"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08312">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="7">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT86092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="80" mass="9266" checksum="2FEF113EAD6D703A" modified="2019-04-10" version="1" fragment="single">MYNGIGLQTARGSGTNGYVQRNMALIRNTKNKIDFRTEEELQKLEDQRTRGPNAEIREHARKRALELKCAEMEDVMREQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NSZ2</accession>
    <name>A0A3R7NSZ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003017">
        <property type="protein sequence ID" value="ROT65908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NSZ2"/>
    <dbReference type="OrthoDB" id="6377435at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36910:SF3">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="609"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="635" mass="71763" checksum="E767B9F69E95FEFC" modified="2019-04-10" version="1">MTLPTSLSINDEARIPLSTQGDHDTEGLIAPTSTQTQESQAPEITYYEASQDQASDSVPQTPQEAVTFEQETVAYGQTPQEPVFEEGLQENQEPVTLGEGSVTFEQTPHEPVTFEQRPQDVTFEQVPQELATFDEVTSEQLPQRPVTFEHESQNTVTYDQVPQEPVTFDQVPQEPVTYDKEPQEPVILDQVPQEPVTFDQVPQEPVILDQVPQEPVTFDQVPQEPVILDQVPQEPVIYNQVPQEPVTLDQVPQEPVTFDQEPQEPVTLDQVPQEPVTFDQVPQEPVTYNQVPQEPVILDQVPQEPVIYNQVPQEPVTLDQVPQEPVTFDQVPQEPVTYNQVPQEPVTFDQVPQEPVTFDQEPQEPVTFDQVPQEPVILDQVPQEPVIYNQVPQEPVTLDQVPQEPVTFDQEPREPVTFDQVPQEPITLDQVPQEPVTFDQVPQEPITLDQVPQEPVTFDQVPQEPVTYNQVPQEPVTYDQEPQEPVTLDQVPQEPITFDQGPQGTVIFEQGPQEPVTFEQGPQEPVILEQGPQETIPFEQNPLAPTSFEQGTVVSEQGPATFEQGTVTFEQRPREPVTFEERPEVPFHSRPNPQSPFSPDQPAQEPFSFEQTFPESHTFQQTSQDFPRAPPLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NYV3</accession>
    <name>A0A3R7NYV3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011047</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="QCYY01002401">
        <property type="protein sequence ID" value="ROT70658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NYV3"/>
    <dbReference type="STRING" id="6689.A0A3R7NYV3"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000004">
        <property type="entry name" value="Glycoprotein 3-alpha-L-fucosyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="108"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="245"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="536" mass="62324" checksum="98965995D51DF07E" modified="2019-04-10" version="1">MGVLLRNHVSWTLRKVVLLVFCLGCALHFLLGEKEDIIGMVRINRAKEEVCSCHVSREAMETETLTKRAQNATTKDWRNLTAEELGSLSVLGRYLYLEEPLGAPQDRTFLILIWKKGLYMEQRTVYEFTSERKDPFARCTLRNCKLTYEDEDVRIADAVVFPLHTTPGPQDFPNRTRASQRWIWLTDENPFHTFMIAEDKDISHYNGYFNWSMNYRMDSDIPVPYGRTLKLAEGERPNNTIDYFSTKSKLAAIMGSNCGGQNGRWEYVYELEKHLELDTYGGCGKLQCPGHFAVDCPALNQYKFYLAFENGDCPEYITEKVWWNSFHKGVVPVVMGGPKESYRKILPPNSFIHIDDFETPKDLAEHLKALSTNRQAYNDLHAWRSEYRVSNEHAYFQSPIYHYCRICEALNHNDPKPKMYNRLQDIWKVDGHCPPPTWKDRLDKANQRFQDRRRVQTATRKSLSSSAADLASRLLLRRGRTKRKAVTGDLSVHSRAVLEAKDQYRLGVSRARLETETFVFRCWKPKISIAETFMLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6C7</accession>
    <name>A0A3R7P6C7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001613">
        <property type="protein sequence ID" value="ROT76753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6C7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="12549" checksum="5DA800BDF158F513" modified="2019-04-10" version="1">MQFLRRFKFPPYDHRGDGHFGHHDHNRSHHDLSDNDRCSLAKVVERTQQFPSTGGPRKRIQNRRPFCSPAVHWKDIQFVLYSKSLQDEINCSCAPGGACSLCSSRVVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PA16</accession>
    <name>A0A3R7PA16_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003168">
        <property type="protein sequence ID" value="ROT64931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PA16"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003882">
        <property type="entry name" value="Pistil_extensin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01218">
        <property type="entry name" value="PSTLEXTENSIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="623" mass="65000" checksum="A304270A1CBBE039" modified="2019-04-10" version="1">MHLPQFLPHASPGSSTPQFLPPRVPRPMPHSPTSLPHASPAPCTPHLLPPPSPGPMHSPTLLPTSPGPCTPPPLTYVSPPMHSPTLLPTCSPAPCTPPPPPTCPRPGHALPHLLPNVFPGPCTPHLLPHVSLLHDSPTFLPHASPGPCTSPHRLLPHASPAPCTPPSPPHVSPGSMHSPPPPPPGPMSPGSPLPPPPQRSPPCTPPPPHVSRPHALPHVLTHLVPRPHALPYLLPHALPGPMSSPPAPCTPPPPPPRFPPGPMPTPPPPTPTFPRPHALPHLLPHVSPGSPCTPHLLPHVSPAPFTPHLLPFPPAPGTPPPLPHASPAHALPHLLPTRVPPAAPCTLPTSSPHASPPLPHALPQPPPHATPSPVAPHALPHPPPHAPRPDSPTPPPRSPGHATPHPPPLSPPHALPTSSPRVPSGPTHSPTSSPTRPPAPCTPPPPPPRFPRPIKRPPAPSPPPPPPRFPRLHALPHHHTPRFPGPMHSPTSYPIAPGSMTPCTPPSYPTVPRPMHSPPPPHGPPGPMHSPTSSPTCSPPHALPYLLPHASPPHAPPPPPPRCPPPPCTPPIPPPRVPAHAPPLPRPPCTPPTPPPRVPRLHALPPPPPPSGLEWNLRPHIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PC95</accession>
    <name>A0A3R7PC95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000936">
        <property type="protein sequence ID" value="ROT81669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PC95"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="722"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="894" mass="96640" checksum="21B3FC7CF62E04EC" modified="2019-04-10" version="1">MVVIRPSSDCTLLLSSASSCLPLRLHSSPHRTARRPLLSEFLPPLSYSSTYCSFTISILSSRINERTQFLIVVRTSSPSESSRLALLSLSTSHPRISDHPTDLICPSILTSLSRNKESFSLVFSLLGRNGLLRPQIFLLLPQCSHPPISFSLLCHSPAPLSHLRCNYIITQSSHESIINSHVLRTTSRYAAFRTSSGAGLRTFTTSRCARFTTSRVRFTESSVRRGLRDVSGTACRLRTSRVPRFTDVLVRGLRSARFTDVSVRRFLRFTDVSVRGLRTSLRCRFTDGLRTVSVATYGRLGRGFTDVSGTRFTDARLRTSWYARGFTDVSAVYGRLAVYGRPVRGLPDGGSDVSRLRTCLQTSPFPSSPPPPFPSPPSPLPLILLFPLLHSCPSFPPSPPPNLSFLLLLSSSSSLPPSRSSKPLLSPPPFLPPYSPPIPSSPPPNLLLFPHSLLPPIPPPSRHLPHLSPLRSPPPPSPSSCPSPPSQPPLRSDRLAFRQSSPPSTHPPPPPPSPCAPLQGPLALPPSPASPLSKPPRPPLSPPLPSSLPFPPPSPSQSFLQSEENFDISYFPLFSTPHFATPFSFSTFSSLASFLAIPFPYFPPLPLPTVTIPLLPRPPTFPLPLSNPLYFQGGREESAGAGGFSSFCFHPLSFPCFSSSSLPLPPNPFLSLSSSGAQCPSPPLPSLPCLLPSSLVSPLSPCTFPLVSPRLHVNLPPFSVPFFPFFLSLLFSFLFLAAPSLFLSPHNPAATSLINFSSAFSLLPYLLCCVYSRPQTSANYSLSSPRNLPLFSSIPLPLICPLFTPLPSNCFLLSLPPPPFYYLPSTPPLSTVPLASPPFSLSPCPPPPSTGLLPPLSTALVPPTPLVSCPLLSPVPLPIPLSFPYPAPSSPPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCH4</accession>
    <name>A0A3R7PCH4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative TRIO and F-actin-binding protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002907">
        <property type="protein sequence ID" value="ROT66662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCH4"/>
    <dbReference type="OrthoDB" id="9943385at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="804"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="995"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1181"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1234" mass="143012" checksum="C91EF0CA5BD9ECB4" modified="2019-04-10" version="1">MSRRQPKGDDPRKTTKGGRPKEDDPRRTTQGGRPKVDDPKKTTQGGRPKVDDPTNQGGRPKVDDPRWTTQGGQPSEDDPMRSIQGGRPKEDDPRWPTQVGRLRKDDLRRTIQGGRPKEYDPRWTIQGGRPKEDDPRRTTQDGRPKEDDPRGTTQRTKGRPKEDDPRRTTQGGRPKVDDPGRTTQERRPKEDDPRRTIQGRRPKEDDPRWTTQGGRTTQGGRSKEDDQGGRPKVDDPGRTTQERPQGGRSKEDDPRRTTQGGGDDPRRTTKGRRPKVDNPGRTTQERRPEEDDPRRTTHGRRPKVDDPRWTTQGRRPKEDDPRWTTQGGRPKGDDPRKTTQAGRPKEDGPRWTTQGGRTKVDDPRKTTPKVDDRRPKMDDLRKTTQGGRPKEDDPRWTTQGERPKEDDPRWTTQRGRPKMDDPRKTTQGVRPKEDDPRKTTQDDLRKTTQGDDPRRTTQEDDPRKTTQRRSKEDDPRRTTQGGRPKEDDPRRTTQRGRPREDDSRRTTQGRRPKEDNPRRTTKGRRPKEDDPRMTTQGGRPKEDDPRKTTQRRRSKEDDPRRTTQGGRPKEDDPRKTTQGGRPREDDSRRTTQGRRPKEDNPRRTTKGRRPKEDDPRRTTQGGRPKEDDQRKTTQGGRPKEDDPRRTTQGGRPKEDDPRRTTEGRRPKKDNPRKTTQGGRPKVDDPRRTTQGGRQKEDDLRRTTQGGRPKEDGPRRTTQGGRPKEDGPRRTTQGRPKVDDPRRTTQGGRPKEDDQRWTTQGGRPKVDDPRSTTKGRRPKEDDPWRTTQGLPKVDDPRRKTQGGRPMEDDTRRTTQGGRPKEDDTRKTTQGGRPKVDNPKKTTQGGRPKKDDSRRTTQERRTKEDDPRKTTQGGRPKEDDQGGRQGGRPRKTNPRRTTPTEPRRTGRRHKEDDPRSTNQGGRPKEDDTRKTTQGGRPKVSPQRTTQERRTKEDDPRKTTQGGRPKEDDTKRTTQGGRPKEDDPRRTTQERRTKRTTKKDEPRRTTQGRRLKEDDPRRTTQERRTKEDDPRKTNQGGRPKEDDSRRTTQGGRPKEDDPRKTTQGGRPKEDDTRKTTQGGRTKEDDPRKTTQGGRPKVSPQRTTQERRTKEDDPRKTTQGGRPKERRPRRTTQGGRPKEDDPRKMTQGGRPKEDDTRDDPRRTNQRGRPRKTTKEDDQGEPQRTTQERRTKEDDPRKTTQGGRPKVDDPGRTTQERRPKEDDSRRTTQGRRPKEDDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD55</accession>
    <name>A0A3R7PD55_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Gamma-aminobutyric acid type B receptor subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_014766</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002839">
        <property type="protein sequence ID" value="ROT67168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD55"/>
    <dbReference type="OrthoDB" id="17569at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06366">
        <property type="entry name" value="PBP1_GABAb_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000063">
        <property type="entry name" value="Gamma-aminobutyric acid type B receptor subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF46">
        <property type="entry name" value="METABOTROPIC GABA-B RECEPTOR SUBTYPE 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Receptor ligand binding region" evidence="13">
        <location>
            <begin position="12"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="241"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="314"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="254"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00073785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT67168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="42893" checksum="CDC457F3F12661A9" modified="2019-04-10" version="1">MPKGPEALESLFQVSFGSVSPALSDRQTFPRFIRTVAPDSSHNAARLAFLTRHAWSTVATISEDHDMYTLALNELVPALESANISLQATVTLSSEDLTEHLHTLKEKDCRIFIASFSPELARKVFCQVYHLRMQGPGYAWMLSGEAQDSWWKTTQGTNCTRSQLAEAVQGAVLVTAHGSIVGEEEAVSGLTNTEFLQEFNQTGQNMTSYVTHTYDAVVWPWAMALAPPRFVSKILEDKDEAEVKGRAKGDVKRGQRRSTHRRHSPAKREVSHHQEKVTGMSQCSSTSQKEDNTEKPTMSWILSRLAKLQQFPLEPHRKWESQRKPSHREPGGEDSANGIFKTDSRRFQFADFDYSRDDIADLILERMQELRFRGVSVSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF00</accession>
    <name>A0A3R7PF00_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022323</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000534">
        <property type="protein sequence ID" value="ROT84473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF00"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12154" checksum="7E08ECE66A34EF74" modified="2019-04-10" version="1">MPILVYTCVVEEFPGWNLGVCLHCRSGRKSGAAVGKELHLGLVRKDLLESRRGRSPPIRMRRKVVKKVLSVEQAEGRGARVRRSIGRKELKKDARNIITAHESAGGSLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFJ8</accession>
    <name>A0A3R7PFJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002466">
        <property type="protein sequence ID" value="ROT70120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFJ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="44196" checksum="CC93E933FE6C0938" modified="2019-04-10" version="1">MATIIHHSHRLPTSHHLPPPSRYHQTHITLTISTIPSSYPFVLNAHFRTAPPESAWRRRGAVLRAGLPPLPLHAPEPAPAATLRSRNDITRNHTRPLPPILSNPLLHFSPLYSLYPSTHSPPLSLSSIPLYLLPNAFPPPFFSTPFLHLSPSPIPSLPFFTSPLPIPSPSPLPFPYSPLPFFFTSPHPQFPIPLSFTSPYSSIPSSHSSQPSLHPPLPLSTAHTSEGCVVDQGLRLPIVEIRFCTFKPPGFWLPSSPSSPPQLLPLSSPHPPPPSPLPFPIPLIPFPYSPPCPLHPLTPARLSRVGHVAASLVAAAFETSAVVTIATNGKDMDLEKSKCPTCFISSVRHRLTGVSWELGCGGDEGAPGARGPGGQVDPRGNRGKWAFVRARRQSKDCPFSFPDATRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJM2</accession>
    <name>A0A3R7PJM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007524</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001955">
        <property type="protein sequence ID" value="ROT73992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJM2"/>
    <dbReference type="OrthoDB" id="6363637at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="40856" checksum="A2BD78651F9685BC" modified="2019-04-10" version="1">MDNMYYFAGISWVFGGVVGVLVAGGLPYSVLQIACSPVSHGGHGGDRDFMVVMLYVNPAAAPFTKPPFPTVCFWALMASAVREQGKVSVSAGGIVKEMGVGECGRPRCPCHGEVELVTIARTSGAFCPTCASSGWWADIPQPQDKLQALLCSIGQWTAPLLVGASSTSSVAQPALTKGDAPKGGAETSKGVSSSTIPSTPLDEEDTFTLGGVYIGSLESHIRTHQAFCSGMNVRSQGCQTGELEASPPVIEWRIQMSTEELSRASPTLEDVATQCSFAGEGEWPRVSRSPSQRSACQVLQVSGEVCVRDARARLAGRTRVEAGRSLPALLLVLLQMLLWLPLPISALTLYFSSCSATWAWRVLLVVLTVTNLSPALTSAVYLVAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PK09</accession>
    <name>A0A3R7PK09_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001906">
        <property type="protein sequence ID" value="ROT74364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PK09"/>
    <dbReference type="STRING" id="6689.A0A3R7PK09"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF1">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="366"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="623" mass="68077" checksum="E5FD0261B2E32618" modified="2019-04-10" version="1">MPMPGESHSDAPAAVPLQVAVQSSALPDSANGHAGGDSPKALNCLECKKAATIVCGGCWQAGYCARDHQLTGWVKHRPKCRPWRIARSSVLGRHMIATRDVAAGELLLEDPPLLLGPKNITEPVCLGCYRPVDGSYVCRGCSFPMCGSDCEASEDHQVECKAVKESGVSVKVTVFGEINSMYECITPLRILSLRDSNPMVWNKLLSLESNLDKRGGTEVAAITQQTVVDIIHDRLRLEDEFDAELIQKVLGIIDTNAFEIRLPDSSIQGIYGNAAILEHNCVANTHRTFDADLNLVVRAAVPIKRGQHLSSCYTDPLTTSFTRQDHLRSSKYFTCQCDRCLDPTELKTFLSALKCSDCATKQAAEKATAKKAADSQPVGRGLRGARRGGVMNRVSQFQTGGGRGQASGGAEGGAGDEGPGPWIVAEDPTSPSSNWRCLACGHSSTDDYPSKITDVVAEEAEELENSPTVATCEAFLEKWGHLFHPDHAIFLNIKYALLHLYGSEEGYELDSLSPIDLTRKEELCRQVLKVADILLPGITRLRGSVLYELYQALFYKARALFMVGAASSEQARRLAMSAMTALKECVRVLSYEPEVQPEGQLGLEAKEEVKQLEEWIKDEGWKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNW0</accession>
    <name>A0A3R7PNW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Neuropeptide GPCR A20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_009092</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002140">
        <property type="protein sequence ID" value="ROT72524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNW0"/>
    <dbReference type="STRING" id="6689.A0A3R7PNW0"/>
    <dbReference type="OrthoDB" id="6351933at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF9">
        <property type="entry name" value="LEUCOKININ RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="100"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT72524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="19591" checksum="EAAAD0DE86CC1A8B" modified="2019-04-10" version="1">MAEHLDTPGTSLPGGVAFQSPQPPDADQILQRCREEVHYLYYTTNDTRILADFTLCEDCNITNEELEILELSGVCRPYDFSYMPLIYYMYASIFVIALFGNLLVLYTVVTSRKMHTVTNFFIANLAVGDLLIMVFCVPFSVASIIVLQYWPFGEGLCIFVNYCQSLVMEEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUP9</accession>
    <name>A0A3R7PUP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001507">
        <property type="protein sequence ID" value="ROT77590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUP9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="63235" checksum="A4BB529E7080DCB0" modified="2019-04-10" version="1">MRPFQKTFPEDIPRKTFQKIFPQKRKTFPEDIPRRHSQKTFPEDIPKFPEDHSQKTFRRHSRRHSQKTLSKDIPRRHSQKNIQKTFQKISEKDIPRRHSRTHSQKTFQKKKDIQKTFQKTFPERHSQKTFQKTFPEDFPEDIPRRFPEAFPEDIPRRHPRRHSRRFPETFPEDIRIPRRHSQKTFPEDIPRRFPRRHSQKTFRHFPIEDIRKTFPEDIPKTFPEDFPRHRRHSRRHSRRHSPERHSHSQKDIPRRFPKDIQKTFQKTEDILERNSQKTFPEDIPRRHSQKTLSKDIPRRHSQKTFQRHSQKISQKTFPEDIPRTYSQKTFPEDIPFPEDIPEDIPRRRHSRRHSEDIPRRQFPEDIPQKRHSQKTFPEKTFPQKNIPRRHSQKNSQEDIIERHSQKTFQKTFPEDIPRRFPRRHSQKTFQEPRRHSQKTFPRRHSQKTFPEISNIPKRHSQKTFPEEDSQKTFQKISQKTFPEDIPRDIPRRHSQKTFPEDIPEKTFPQKTFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUT9</accession>
    <name>A0A3R7PUT9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001493">
        <property type="protein sequence ID" value="ROT77684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUT9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="632" mass="69795" checksum="48598CB2361131D0" modified="2019-04-10" version="1">MTLLCPSPHLSVAFPPILPSLSSLPLPLPLSVHLSLSLPSLSPFRSISPFPSLPLLPHSRSISPFPSLSPLSLPSLFPLPSLSHSSLPLPPFPSPFFPFPSLLLLPSFPPLFSLLFLYLSPFKVHLPPSLHPSSNPASYTPPPPATALLSCCVLKKGWKGRLGSRRWHSLDPSPLPSSLPSASFLLPFSLLVPTSLFFFPPLPSTSLLLPFSLLVPTSLFFFPPFFSPLPSTSFSSPFFASRSFLFLLPSLLLSLLPPPFFSSLPSTSFLLPSLVLFPSSYFFSSLPSISFLLPPFSLLYLYLLSSPLFPPPPFFSPPLPSSIRSSLPSPFPFSSRPPSSLSPFYLTSFPYPFSFLLLSSNPPQISRLLPSLPSFRFFSFFHIPPPSLPPFLISFSSVLRFYLLLSFLIFLPSPFPSPYPKLIQFPFLLSSSFFFLPFPSFTHISCPLLSSLLSPTPHISNPFDSLFFRLPPLPFLPFLPLAWRAALEGSFGRTAWGAREASTRNLRPFIDALFYLHSVSPSLAGGRVRGGVECAWRQSLRPNRRSPTRRSAVQHAQLRWTTPPPLSEDKRQTARQTAKFHQDHVPSPPNLNTPSPTPFSPPHPFLHPPSTQIPSTAKHVSTPPSPFLSRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVA5</accession>
    <name>A0A3R7PVA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003183</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001430">
        <property type="protein sequence ID" value="ROT78095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVA5"/>
    <dbReference type="OrthoDB" id="6390783at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018526263" evidence="3">
        <location>
            <begin position="18"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="258" mass="28211" checksum="EBEFE8089937BF00" modified="2019-04-10" version="1">MGTHILVLLLTAKLVASTKLCSEWASTIDDLADEVSQSKWEKIYILFVSEENDTTFNIRFSSSQSVDLNIPEAYVYYVGEVYHEGAVFGDCAQISPVCNTYFHFWDKNHLVGEFVTNSFSISSQSPLYYLACGSLLQRFPPAPLRRRNLSLPGVEPTEPQASRPSVEPTEPQPNVSLPGPGPKQPKDQDHQCAAHTIGLGIVGAALVFLLTFVCVAGWRARRAAESPKLGAAKGHSTASGHESENSIYGMMEMGQTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVC8</accession>
    <name>A0A3R7PVC8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001426">
        <property type="protein sequence ID" value="ROT78143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVC8"/>
    <dbReference type="OrthoDB" id="6355343at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="25121" checksum="22FF2988439FBE4C" modified="2019-04-10" version="1">MATFDDAELYRHPQYVEGLVHWHERFREPISPALKEEVYANFKFSWFWKDHQNKKRIQQILDERYNFVPERPYVASRAFYQNVTRVRVTCIYCTCDLLTYDILQAHNAGRKHKKHFEGVEINGLGQSGSHRTNELQQMANASGAINRDLSASGHKSPVNELKPLMALELSTVNHRQTVGQHNHSDASVPQTPAVARRKTHAPTTVWRSAKKRKSSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWE6</accession>
    <name>A0A3R7PWE6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001273">
        <property type="protein sequence ID" value="ROT79213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWE6"/>
    <dbReference type="OrthoDB" id="444119at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="143" mass="16146" checksum="9A1AD235B6D2A2D2" modified="2019-04-10" version="1">MRAFWGLEALPENASPLVSSGTSSSGQGALGGKETNEPRRLPPNRFLDHVNQVYFNGQLDLDKKAFLGNSFRLGILNGDGDVTYPSGARRRKPKGYPPYLRKEKAKRREEGREEMPQKEGRGEEVNYVGPRSVNRMQYELDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZG3</accession>
    <name>A0A3R7PZG3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000894">
        <property type="protein sequence ID" value="ROT82030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZG3"/>
    <dbReference type="STRING" id="6689.A0A3R7PZG3"/>
    <dbReference type="OrthoDB" id="6350214at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT82030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="416" mass="45952" checksum="96CA80BFF9D98397" modified="2019-04-10" version="1">MKLIPNLTHIVVLNLSMTETIDQVLELIGLNCPEIRELDVSHTAISERGLPRLCYDEATERPLCQKLTKICVLGCVHHPAAGELPAAKLTKICVLGCVITPRPVSFLLQYIPTLREMDYDNVSSPICVLGCVITPRPVSFLLQYIPTLREMDYDNLPPSPSATFPFLPFLLSAHPAITLAAHTFPKIKIVQSRLQLRRENPMTSFFRPRELRHFPPFRPKFGAAAIAIMAATRTQDNSCLRGGESAKNSWSRVIKKEDNLDCFWGVLIACYWVYGVFNVMKEWGLTPANIGTCEKLHLRVLTSTNEVVDPEDVDTAIELCPYATNFTLSNAYVDNDVLYKVMRMENLTHLRITNSEGLTLDFHEGVLPVLTVKGHQLHSLLLVNFTTVDVAGESGVTEGWGGGRGGGGVGGGVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q205</accession>
    <name>A0A3R7Q205_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Na(+)/H(+) exchanger beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015547</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002936">
        <property type="protein sequence ID" value="ROT66412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q205"/>
    <dbReference type="STRING" id="6689.A0A3R7Q205"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF126">
        <property type="entry name" value="NA(+)_H(+) EXCHANGER PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="11"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="11">
        <location>
            <begin position="233"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="572"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="635"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="77523" checksum="9071AB4D8FAF18DF" modified="2019-04-10" version="1">MQGFHQIHWLSNKIPESCVLIILGVLLGVVVFFTVDDGNGTSSCSFNFEVPHFTSDKFFFVLLPPIILESAYSLHDRAFFDNLGTVLVFAVIGTLFNIFTIGPALYGVAQGGLMGTIAIGFTETLVFSSLISAVDPVAVLAIFQELGVNKDLYFLVFGESLLNDGVTIVVYTTLTSFVTMEVISAGQYALAVASFFIVVFAGAVIGILFGCVTALITKYTAEVRGVALITIVMNHYRMKKIGLQEQFITAYGGLRGAVAFSLANMLDQTIDPRRIFITTTLMVILFTGFIQGISIKPLVNLLRIQKKRSDHKKLNEEINDTAMDHIMAGVEEILGQHGDFYLRELIIHYNDKYLKKWFVKPCSESKLTRLFEKIAISEHYAHLYGPVAMIEDKVKPLVTKSSASKRVRTISVSPSHNDEILLQPNLTLEDDEDDEFEEAETKVIQPAEPVELRRKPSYLPIRRSRVASESSATEPQAQRSHDAQALRKAFRNNPYNKLHYKYNPNLVGEEDQELAEHLHRRHLNARRMTRLASCSRLPVSNIAESLRPKTEMIFGHLEDGVAELVQRHRERRSTMSLRRRPPSLQACFSSPEPGHPMVPSSILRELREVSEPRSSLPDIRDCDSHSRLSATISMRGERQQFFPDRSEGEKTTSPEVTFQNEKLEELVPMVATSNTQPSSPKKPDSENEDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3M7</accession>
    <name>A0A3R7Q3M7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000405">
        <property type="protein sequence ID" value="ROT85193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3M7"/>
    <dbReference type="STRING" id="6689.A0A3R7Q3M7"/>
    <dbReference type="OrthoDB" id="19014at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="338" mass="37747" checksum="BF075BB5F7DB66FE" modified="2019-04-10" version="1">MQHGANLHARTKNQETPYDICEDAELRERIMQLINEQETKRLHEQTRRVRRAHSNTRTQSVRRTSIREKTLTPKKEAQEEARIRLQLENKKKPLQEDSPALGGLRAVRERGDTAVLTTFPAVIPANNINNNNNATKENFLVEEEEEELKKENKEKEKEDTGKESTIHEEEENRALPPPAVVVKKEKELVTRSSSGSSSLNGGDRRETNSQEKEKVEELVSTPPVPPPRSSSTSRPDIIATTGTVSGGNVNGSGMVTHSGEGGTDLKKQRAMSRASQNSYTLAPASSTYSLSTPEYDSRSHGRNPEFTASSVRVDTVTYRPPPSPSLTPRKFVETQQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q6Q4</accession>
    <name>A0A3R7Q6Q4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA helicase</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_011818</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002496">
        <property type="protein sequence ID" value="ROT69945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q6Q4"/>
    <dbReference type="STRING" id="6689.A0A3R7Q6Q4"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18044">
        <property type="entry name" value="DEXXQc_SMUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004483">
        <property type="entry name" value="SMUBP-2/Hcs1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048761">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00376">
        <property type="entry name" value="IGHMBP2 family helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21138">
        <property type="entry name" value="SMUBP-2_HCS1_1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase SMUBP-2/HCS1 1B" evidence="13">
        <location>
            <begin position="17"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="11">
        <location>
            <begin position="201"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="12">
        <location>
            <begin position="429"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="499" mass="55142" checksum="EB1BE400E8E54019" modified="2019-04-10" version="1">MTKEKAQLSRNDWIALHCSLLEEERKAEVSAAQSEVEGASLKVLEARGVVLGHLVISERSTGLYGRPMITFVPARKDAVLPANNFSSGDIVGVCDSGSGQQCATGVVKYVSQKNIQIVLDDDADELDSLSDDTQLRLNKLANDVTYRRIKSGLTELDKLINGPAAHTVSVLFGESPPRSAAPSLPPQLTGADGKIQLFNKNLDNSQREAVEFAIQRSDLAVVHGPPGTGKTTTIVEVIRQHVKLKSKVLACAPSNLAVDNLVERLAAAKVRVVRVGHPARATPLTQRYTLDCLMHHSDESQLLKDIHRDINDQLKQLKTAKDRGKRQHIRREIKTFRKELYEREMRLTKQILMTSDVILATLTSSSNDGPLKLLREDFFDVVVIDECSQAIEAACYMSLLRAPKLIIAGDHCQLPPTIVSKEAAEKGLELSLMERVINQCGEEVVRMLTVQYRMNTDIMQWASTAMYQDRLVAHSSVASHLLHQMQGVTTNEDTGTVHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJU2</accession>
    <name>A0A3R7QJU2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_012004</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002520">
        <property type="protein sequence ID" value="ROT69772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJU2"/>
    <dbReference type="STRING" id="6689.A0A3R7QJU2"/>
    <dbReference type="OrthoDB" id="10251242at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050362">
        <property type="entry name" value="Cation-dep_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509:SF93">
        <property type="entry name" value="CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10509">
        <property type="entry name" value="O-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT69772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="258" mass="28388" checksum="182E1D8408E578D4" modified="2019-04-10" version="1">MLLQLINEGRQTYEVALRKSVVLLSDSDTVPLDRSLKMSSMKSYYNADPLVQYCVKNSLRLTDVQKRLNDVTLQHSRAAMLGAPEVLQLNSNIMQAIGAKKVLDIGVFTGASSLSAALALPPEGKVHALDISEEYTNIGKPFWEESGVADKIRLHIAPAAETLQKFVDGGEAGTFDYAFIDADKTSYDRYYELCLTLLRPGGVIAFDNTLLDGAVVDPSKDTPNTVAIRKLNEKLKDDQRINLSFLKIGDGLSLCFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRD7</accession>
    <name>A0A3R7QRD7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative acid sphingomyelinase-like phosphodiesterase 3b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001777">
        <property type="protein sequence ID" value="ROT75389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRD7"/>
    <dbReference type="STRING" id="6689.A0A3R7QRD7"/>
    <dbReference type="OrthoDB" id="348678at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045473">
        <property type="entry name" value="ASM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF57">
        <property type="entry name" value="METALLOPHOS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19272">
        <property type="entry name" value="ASMase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sphingomyelin phosphodiesterase C-terminal" evidence="4">
        <location>
            <begin position="233"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="44705" checksum="B5355633D6A841E2" modified="2019-04-10" version="1">MIESPTGGSGPDPSQPGTFGDYECDAPLALVESAVDAMKSLHPDPDFILWTGDDTAHVDDKYFSTAKVVDIITSLTNVPPKENELQTQVADLWKDWLADEYGQFKFSGSYSRDISNTSVSVVALNTLIWYKSNQETASVSDDDPAQLFEWADATLSDLAKRKRKVYIMGHIPPGTFERYQQKKEGFHWYQDRFNKKYIELVQKHAAVIKAQFFAHHHTDSFRLFFDAANATHPISYMLLVPGVTPWRSSLSEETGANNPGIRLVTYDTDTGLVKEVSTYYLDLTQANSNEKANWKLEYNFTTEYHLKAINPTTLYNLTKTMKTNRALFDRYYTANTVSLEDPEVCQAQCQQLHWCAITEVDYERFYQCNAASSMSSWAAGTLAAVGALVLRHRQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRQ1</accession>
    <name>A0A3R7QRQ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRQ1"/>
    <dbReference type="OrthoDB" id="6374816at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="687" mass="76855" checksum="61C6291A0D5362C1" modified="2019-04-10" version="1">MTTKPCFSSGCRLVTENLSSMGNYGKEKPSTSSKGFEMPTEPLPKFVGNNPDSSAVGTGLSSPSRSRQPFSYWVHASPSSGKSTHQQHSPPRSPKLLPFLRQTPRPGRNQFTELPSSYPVTFPVYAGRASISREFFSSDSTAKSSEESSHELNASRTDIATNVYEHPSPISISPPEVSTTMPSPFLRRSGNTQENIKMKRFKGTGHRWVWGKSGRSTTTAPQLTTDSRLDTRVADTYALPHKVPERHFPVAYGGDKNFVHHPQHVLASPDEEYNSVEGEDSPFLQDTQASFTNEPNYNQMLSNRDAIDRDYTHVYHPTSSYSYIQPDHHNYHNEPVNHNYHSHPDDHSYHSHPDDHSSHSHPEAHNYHRKEKPHHPIETKFSLTFPINKTMSVRWYKALTMNASFTDIHNPFKPFLQFGFSSGMEPVYHPHTGYNTLHGHHTPPYKRLIDISSGDTPGDRHVSENPQDSSFDIFNILPKIGLSFARGRERVASAFDPFGSIMRGWDSLKNLFGASDETGEEVSETPYAPEYIPTTEDQPSETYLQSNDVHDPYIGPYTKKPSLQFYETSVDDQLPIHMGKYKPPAIYIPVDGMYDSSAATLFKTKEPYSSTARMHTTHTDAYAVPQGTPFPSAGMNSAMTRLNTGLPSYDRVTHAGIFWPHGVGSGGGGDPFHVVKAPNISQSTRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QUL2</accession>
    <name>A0A3R7QUL2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001321">
        <property type="protein sequence ID" value="ROT78851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QUL2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="580" mass="62620" checksum="8E4CFE6C19B735D1" modified="2019-04-10" version="1" fragment="single">HPTIPPPHPPPPPLVPPPHPLLSPCSPLPPSPSSPPSPPPPCSPLFPPPLTPYPLSPDSSLYPFPPPLLVIPSHTPLFSLFLISLFSFIPSYPLIIPVSNHSSHPPSPSPFIPSTSFVPFASFSILLLSLLPHSPFCLILPSTSFLPLHHSPFCLFPFCLSLPPVSFSLLFPFLLSISPSLPLFLPSCLFYLLPHSCFHLFLPTASPPSCLLLPSVSFSFLPHSPFYLFYPSTPSPSPLSPLLLSSPPASFSHLPSLSLPTLSPISLSLPHASFFPSTSLSLLPLLPSASLSLMPLSPIYLSLPHALSPLLSSCLFLPCPPIYLSLLLPLSLPSTSLSLLPLSPISLFPCLFLPSTSLSLRLFLPPFSHASFSIYSLSLSASLLPIYLSLPPASFSHLPLSLSASLSHLPLSPSCSFSHLLPSCLSLPSTSLSLLSLPLPLLSLLPLSPIYLSLPPASFSLLLPPAFSALNRGPLAQPHSLSADETPGCVGSFSLRSGERRVPLTRLETDKGKRWETNSNGWWFLDEMKATRIIGCFGSFSLSVLVDTPISSFSLIKHQISQLTRRSRYRQTLHRSLYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QUW5</accession>
    <name>A0A3R7QUW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative obscurin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002126</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001284">
        <property type="protein sequence ID" value="ROT79156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QUW5"/>
    <dbReference type="OrthoDB" id="10012075at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF3">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00406">
        <property type="entry name" value="IGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018597993" evidence="2">
        <location>
            <begin position="21"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="233"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="283" mass="31379" checksum="B46B75B99727BC04" modified="2019-04-10" version="1">MAALLLRYLVLGFTIAGGAGKEMRPPMLQRPGVLLGPSPRTTSITATSSSSSSSSVLSPSSSSSSYIPSAPDPLSPASFVEAPERLQPHSRAQEEEDDYLYEDYEEGDGEYEDEQEEEVKVKVREPFFGTANSTTTTVFLGATATLDCTVHDIANESVTWMRRVDDMLELLTWDTHTYAKDKRYSVASDSGVGWRRWRLLINGSQVEDQGQYRCQVATQPPKILAVTLVVTEPLVQVVDERGTKVVDKHYNSGSMIELKCVIEKVPFPHLTVNWLRGSTIRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWK7</accession>
    <name>A0A3R7QWK7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="16">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MCM7</name>
        <name evidence="18" type="ORF">C7M84_000404</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="16"/>
    <dbReference type="EMBL" id="QCYY01001058">
        <property type="protein sequence ID" value="ROT80844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_027210876.1">
        <property type="nucleotide sequence ID" value="XM_027355075.2"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWK7"/>
    <dbReference type="STRING" id="6689.A0A3R7QWK7"/>
    <dbReference type="GeneID" id="113804228"/>
    <dbReference type="OrthoDB" id="3207464at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000004">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1640.10:FF:000007">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000288">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 16" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="17">
        <location>
            <begin position="334"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT80844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="721" mass="81685" checksum="3D16A021ABC3A656" modified="2019-04-10" version="1">MASKQRDYDQEKEAIKRFLAEFHTVGDDGRKSFKYATQLVELAHREQVSLTIEIEDVAEFDPDMAEAIVQNSRRYLNLVSEAVYEMLPDYKQRETVARDALDVYIEHRLMMEQRTRQPGDVRDIRNRYPPELIRRYEVYFKAPSAQKPVAIRNVKASHIGKLVLVRGIVTRCTEVKPMMQVATYTCDQCGAETYQPIQSSSFMPQLLCPSEDCRVNKSGGRLYLQTRGSKFIKFQEIKVQEHSDQVPVGNIPRSLTVMCRGEQTRLCQPGDHVAITGVFMPLLRHGFRAMMQGLLSDTFLEAHRIVQMNKTEDDELGADELTESEIKQIAEENFYDKLAISIAPEIYGHEDVKKALLLLLVGGVDCNPNGMKIRGSINICLMGDPGVAKSQLLSYIDRLAARSQYTTGRGSSGVGLTAAVMKDPLTGEMTLEGGALVLADQGICCIDEFDKMADSDRTAIHEVMEQQTISIAKAGIMTSLNARVSILAAANPAYGRYNPKKSVEQNIQLPAALLSRFDLLWLIQDRPDRENDLRLAQHITYVHQHCAQPPTQFKPLDMKLMRRYIALCKKKQPTIPENLTDYLVSAYVEMRKEARNNKDMTFTSARTLLAVLRLSTALARLRLVDAVEKEDVNEAMRLIEMSKDSLNHTEERTGRAQTVTDKIFTLIREVAGENRVVKLGEIIERCTSKGYKPDQVNECIEEYEELNVWQVNQARTKLTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJ79</accession>
    <name>A0A3R7SJ79_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 8">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="QCYY01003452">
        <property type="protein sequence ID" value="ROT63304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJ79"/>
    <dbReference type="STRING" id="6689.A0A3R7SJ79"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00326">
        <property type="entry name" value="alpha_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5025086900" description="Carbonic anhydrase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="180"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="196"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT63304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25273" checksum="8708EFD08E806B84" modified="2019-04-10" version="1">MAFKEAVFLLLLFQTLNREAAATHWTYKGVEEWAEESPDCAGKRQSPVDISEPKAFVAPPFLFKNYGLINVSLQNNGHSLSVRLHPQQEQQRPRLAGGGLSGTFDLDGFHFHWGSEDSRGSEHLLGGCAFPAEMHLVHFKENNKTAPNPYFCRYKSVKEALKYDDGLAVLGVWLVPGRDSDSSAREDLGGGSTSDSDSKSTTRKTLEDDGTSDSDFKSTTRKTLEDDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQ77</accession>
    <name>A0A3R7SQ77_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative neuropeptides capa receptor-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_011162</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002412">
        <property type="protein sequence ID" value="ROT70555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQ77"/>
    <dbReference type="OrthoDB" id="6347360at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001594">
        <property type="term" value="F:trace-amine receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050569">
        <property type="entry name" value="TAAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24249">
        <property type="entry name" value="HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24249:SF307">
        <property type="entry name" value="TRACE AMINE-ASSOCIATED RECEPTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="244"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT70555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="559" mass="62886" checksum="81C87F6EB74BBC2F" modified="2019-04-10" version="1">MLRRKPCPFSRENIKTAHTLTRVKAQFIYTDCKIGFIARPGCLTMGKPQGCLKSHAVRSILLMVITAVCFARPCSSLHNHGNDIATRNRVSDRLIANRILPPMHFREKAKGSHQRPATNNNQHQQITTSPKAQVNRSVFSSLQRPPTLPDSAVLSALPSRRLLSTIQDQIQTDDDLYKFIAIHDDFLILCNHPPPTFSNKFFYNEHPEKHGLNGVWNFLPFSCRVGEVCLIVLVACVATGGVVGNLMVIVVLLRISSRNEESNMLRLSLAVADFLTCAFVVLPSLYEHVKPFLTPTEPIIVHRVEEMHDIIPGETVDRTDVYFPLRFFQGLTFASCSIVSLLTLFLLSAERFVMTGRGLMYKHYITPPRVRQAMVISWVIGWVNSSLMTIFGRTVATVTWMTFVKIPIGLSNFAHEDLVVYTCYIIQIFLLSISIPATVLLSILSIKNFVQEQNRVRESSEGEMALTTYAGKQRRPNTATETFVAGFCRVNAKARAAADTWWCICKGMRPVKIECLNYGLQDSDSSRARTPHISNINPPCGVVSGRGMVPQRLRLWLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRA4</accession>
    <name>A0A3R7SRA4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Hairy/enhancer-of-split related with YRPW motif protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_010028</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002270">
        <property type="protein sequence ID" value="ROT71647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SRA4"/>
    <dbReference type="STRING" id="6689.A0A3R7SRA4"/>
    <dbReference type="OrthoDB" id="6371181at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11440">
        <property type="entry name" value="bHLH-O_Cwo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000079">
        <property type="entry name" value="CLUMA_CG001539, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050370">
        <property type="entry name" value="HES_HEY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003650">
        <property type="entry name" value="Orange_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10985">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07527">
        <property type="entry name" value="Hairy_orange"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00511">
        <property type="entry name" value="ORANGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158457">
        <property type="entry name" value="Orange domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51054">
        <property type="entry name" value="ORANGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="166"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Orange" evidence="8">
        <location>
            <begin position="248"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="301"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="301"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="40683" checksum="C5AE04641E00C4BB" modified="2019-04-10" version="1">MTCWGQSCEWWAECGAPPLPPGCWHPLPPHHALAAAAPRSRISAVSLLQGDRVTEGGATGCVLREPRLAFCRFALLPSFWVLAACASRKSSARGSEFAVRAGPIAGCAEEQAASEAVLLQRMCKRALKDLLCHVFWHVIPQVEQKARLVVASSERGGGAHGSTFFYDPLSHRIIEKRRRDRMNNCLADLSRLIPTYYLKKGRGRIEKTEIIEMAIKYMKHLQAHACNQMENCEVTTKQEWSGNQMEQFHLGYQECMSETMQFLVESEGFFSGDSLCVRLMNHLTKHCEKILNSEGYVMRQNGASSSSSSGYHANSSSTGSSSDGNGNSSSHASESKDTLVTGLIVGPPKGRSIAAAGPERPTQGNFFSNGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STQ6</accession>
    <name>A0A3R7STQ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001870">
        <property type="protein sequence ID" value="ROT74629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STQ6"/>
    <dbReference type="OrthoDB" id="6375801at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="42971" checksum="1749C2FAAE63B5B5" modified="2019-04-10" version="1">MDNVIMCDPLGEEDITVEEDPLGYNEELEVKDEPFEFFDDPSCWPSHRGANCNDDDDEEFPGLEILSVDDIAKDDGDDSNHLELIEMIEVGGPDTCSSAADLSLPEEVPSSSSVADTLAEESHSPSQFSTDLDKEKLDALVKREANILKTQERREKEMNQLINLRRRVRRQELKIKQVGGSLLSNLDTGQDPLKDKKLVDVPPLALGADGYGETPKGKRKVGESSSSVGRADAKADSMKDVLQDAEKETELRTQLCTLRDSKEILTYNLWERNSSGTVNSKLRSASEPVAIVAAKFLEELSLLKSHIQRIFCQFDSARSARERALDSWDEVTFHLDCSPLPIYPYPGQENGASEPVTMLTALSGYIWSHSWGMFALGVPRTLPQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVK2</accession>
    <name>A0A3R7SVK2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001554">
        <property type="protein sequence ID" value="ROT77220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="613" mass="65544" checksum="DD32DCE7A5D0E28C" modified="2019-04-10" version="1">MTRLAPTLGFGRRGQPEGIFRKASRAARRNLSLGKAGQPKESFPRQGGSPKESFPRKAGAARRNLSSARQGSPKESFPRQGGAARRNLFLGKAGSPKESFPRKAGQPEGIFPLFPQGGGSPKESFPRQGGAAEGIFPSARQGSPKNLSLGKAGQPEGIFPSPRRGSPKESFPRQGGAARRNLSLGKAGQLEGIFPRQGGQPKESFPRQGRAAHLSLGKAGQPKESFPRQGGAAKEARRGSPKESFPRQGRAARRNLSLGKAGQPEGIFPSARRGQPEGIFPSARQGSSKESFPRQGGAAEGIFPRRNLSLGKAGQPEESFPRQGRAARRNLSLGKAGQPKGIFPRQGGAARRNLSLGKAGQPKGIFPSARRGRRNLPSQGGQPEGIFPRQGGGSPKESFPRQGGAARRNLFPRQGGQPEGIFPSARRGQPKESFPRQGRAARRNLSLGRGSPKESFPRQGRAARRNFSLGKAGAARRNLSLGKGAAEESFPRQGRAARRARRGSPKESFPRQGRAARRNLSLGKAGSPKESFPRQGRAARRNLSLGKAGAARRNLSLGKAGQPEGIFPSARRAARRNLSLSRRNSXXXXXXXXXXXXXXXXXXXXXXXFLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SX23</accession>
    <name>A0A3R7SX23_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative gamma-aminobutyric acid type B receptor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_001884</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001251">
        <property type="protein sequence ID" value="ROT79401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SX23"/>
    <dbReference type="OrthoDB" id="2150267at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF46">
        <property type="entry name" value="METABOTROPIC GABA-B RECEPTOR SUBTYPE 3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="669"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="752"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="828"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="851"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="701"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="545"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1053"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="561"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="580"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="605"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1063"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1219" mass="132734" checksum="260374D66E4EE462" modified="2019-04-10" version="1">MLKVGPISFDCPDRVGVTAFYQIQGGAPVKVALYHPEGESLDLSCPGCHALVWPGGEVPASRVFKLRVETVDPAAFILMSSLATLGILMALAFLAFNLTHRRLKKFVSLPLPPLFVLSALPFLSSYSSLPFIYLFSLSLFILSFPPSLLHLNISVNDSLFFSLPFIHFFLSPSPSLLFIYIVHRALLFPSHFIFSPSLPLPFPSLLSIFFPLSSVYRPIRFLHTSFLSLPFSIPSLPIPTLTPPPSSPSPSPFPFPFLPSNYHPSSLPFPSLSIPPISHPHLPSPSLIPNLISPSNSHPHLRPSYPPIPTLIFLPSPPITTLLSPIPSKFLTLHHPSPSLQFLTPSSPPFLSPPIPTSSPSPSLQFPPSSPPFYPSNSHPHLPPFPPIPTLIQFPPLPSNSHPHLPPLPPTFHPHLPPFYPPIPTLISPFPSNPRPNLSLPFSSNPTLISPSSPPHPHSLPSLHSTLISPFLPPIPTLISLLSLQFPPSSPPYPSNSHPHFPSNIPPSSPPLLPPIPTLISLPFSNPTLFSSPIPTLISSPSPPIPTLPLPPSPPIPPDLSPFSSLSLAQFPPSSPPFYPSNSHPHQFHPLPPSPSPSSPALRASPPPRPPPSPNSHPLPPSLLLQSPASTLIPPFSQFPPSPPSPSPPIPGLISPSFPQVHQALQSRLNNTTVVGTVLVYTAVILLGLDHATLPSPHYFPVVCTARAYLLSAGFSLAFGSMFTKTYRVHQIFTRSNSAGVVKNKLLKDKQLIGVIMVLLVVDIIIVSAWMGVDPMTRHLHNLTLEEHREVVFQPQGLLVSVGVYMAWETRHVKIPALNDSQYIGMSVYNVVITSIIVIVAANVLGERTTLAYVIITTLVFVSTTTTLCLLFIPKILTILRKVEEDPIVESMGLKIQSNTRRLLTEDKRERFYRVEIQNKVYRRELLKLEQELQKLGTTAGGSPTLPLAPGGKLLVGVLGSTAHPPSLRLLTPSFKSRLVKRSPLKSRIGRNEEEEGGEEGIVELRYTLNFSTPVLHEADLPFSMSSRGDLPLCVNSRDLPFSISTHIQHGPRVSFQEDLKSGKKSKKKKSKTSSRSAGNSRSSKDIRLKMEWSACLSDEKLSPPMVEYKVSDLGLLCPLRRMKMAKGEDEKLISEGSAAGEGMGNSYCSAAAASALNHRWRAQVNQPEASKIKKANTTSSTFSSMTTEPATVASGVARSNAHVFSTVIVHRVGGNVHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYK3</accession>
    <name>A0A3R7SYK3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_025216</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000944">
        <property type="protein sequence ID" value="ROT81636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYK3"/>
    <dbReference type="STRING" id="6689.A0A3R7SYK3"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="159"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT81636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="50904" checksum="2DCA87F64314560B" modified="2019-04-10" version="1">MAALRAGFLAQNLYRTHFSKVSRFNYLYAALFHSSPPLNAEGMPLKMPSLSPTMMEGTIVKWLKKEGDPIQPGDALCDIQTDKAVVTMDTEEEGILAKILVPEDTKDVKVGTLIAVLAPEGEDWKTIEIPAGEESAASATTAEDTPAAAAAGGGHAHGNYGPSVRLLLEQYGLAAEQVPPGGPHGILLKGDVLKYIKEKSLQPLPVSAVPPPEVPKPAVAAAPVAPAPTPAVPAPPPTIGVSEDGYEDIEVTSMRRTIAKRLTQSKSGIAHSYGTLECQSDKLLALRKQYKNEGINVSVNDLIIKAVSVALTKCPEMNCVWQGDQLTYASQVDMSIAVATPTGLITPIVRGADFLGIEEIASQVRDLAARARENKLKLDEFQGGTFTISNLGMFGISEFSAIINPPQCGILAVGSGIVKIDENGSPVTCMRATLSYDRAGVDDDTAAAFLEELKNILENPVTMMVGGYKSQVDHPLAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYK5</accession>
    <name>A0A3R7SYK5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000936">
        <property type="protein sequence ID" value="ROT81675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYK5"/>
    <dbReference type="STRING" id="6689.A0A3R7SYK5"/>
    <dbReference type="OrthoDB" id="6379292at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045323">
        <property type="entry name" value="CCDC34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025259">
        <property type="entry name" value="CCDC34/181"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23247:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23247">
        <property type="entry name" value="NY-REN-41 ANTIGEN L15 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13904">
        <property type="entry name" value="CCDC34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coiled-coil" evidence="2">
        <location>
            <begin position="191"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="332" mass="38674" checksum="F18792941A89DA9A" modified="2019-04-10" version="1">MIDDFFDDFFDDKGTNASVKSVPENEILKKTNAKELSDIVNQTRKLALQVENKNSSSDKETTYSESFEEVDKDSESREKTTDSKSASSKTETSSENERTRTPDSTASHSKSQISAQTSSQRDSSVSPEELDSQKTGTYSIEEGELKDIAREKSEGSDRSLSDDETLPSSRSQDISVSTVTERPPRGLSRLKLRSQNEVTKWLQKKRKEEIQRRRERKRAEELKLEEEEKKTREKQKLKRRARAAYREWREMKDQEEEESKRRQQEEEEEWAKAQQRRLATSSQAYVSWLNSHPRFSRRYDSRAYSGGRVVTYYDRGRPSSPTMVNPVPWRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T178</accession>
    <name>A0A3R7T178_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000427">
        <property type="protein sequence ID" value="ROT85159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T178"/>
    <dbReference type="STRING" id="6689.A0A3R7T178"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000300">
        <property type="entry name" value="FAD-dependent oxidoreductase domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF23">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13738">
        <property type="entry name" value="Pyr_redox_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="507" mass="57282" checksum="AA102EC443A74BC3" modified="2019-04-10" version="1">MRDQHNQEFVCRYVVVATGLGVPNSPSFPGSELVEGYEDVSTDPRVFEGKNVLILGRGNAAFETADAIYGNTNMVHMVSRSRARLSWNTHYVGDLRAINNGLLDTYQLKSLDGLLEAGVEDMALERRAGRIYVQFPWEADSLRQIQAKKERGEEIPTENDFDNFSLREGYDYVIRCLGFKFDFSIFNNSSMPSKSIKKTKYPAIKFSYEADRIPGLYFAGTVAHSLDYRKSAGGFIHGFRYTVRVLHRLLEWRHEGQRWPVTSYSTRDLLNVLVKRINEASAPYQMFGELADVILLREGGRRFEYLEDFPVHLLARLEAVTGRDAGPLVVVLMEYGPDFSGPDKDTFRVDRATGDPLEAHRSNFLHPVFYYFRRLPTESEMLHKMGKSALPKPERVHHVLEDFLTVWTAQQSHILPLRRFLEYVIGRDLRHHNAHVCLSHSFTNGRPPPLCPHGGSVGGWAIHPVAPTPTGQLQGVARPARPANYTLWSRPSVRATPPAPLAAAATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S931</accession>
    <name>A0A423S931_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004595">
        <property type="protein sequence ID" value="ROT60729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S931"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="303"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="977" mass="111069" checksum="F3A71E3D452A84A5" modified="2019-05-08" version="1">MKWTSRFLGASRLGLAFRYLLLAWIVPSKTTSFIQMPVGAYTKHDICFGKYFKAITTFGKLVLTSSFLLVYRTLDTSDGTMSVKDYCLQKLGWSNTKFRETFNTSERDILIKDPHANDFTCDISLAFKLITTILGNIIEPLKKDLRDLKNMRNRVCHEDVDMDETELKDRFSNLKVVCRNILEGVGTLAAEDTSTLVLDIEKGLQDLAEAKLDVLDVESYLHDVENFRKEKHSKMITEGRKELMDTYSKLKILNPCTWLSDNKFISFAVDKIFTEVKLMEGVRRVMMNDILNITSLKQRFIARLIIISGVMGAGKTSLHRYILDEWCKRSLTVIGLSAIDMVIAIEMKTVSSSSLVQFLREQLLCRTCRSFSENDIIPILQDMNILFAIDGMDEANSHGKALVREITHKFTNSHIIVTTRPEHSLELMQMAEDHIVLHIEGFDHESQIQFVEKVFASIYSQNTQGREAEKFLEYLSTTCKPLMSHFALPLTLALLLVLWFDDSTKMSSITTITRLHHKIIEMCQQKLVARLEAKGDGHAVSLTRKVRRWVLQLGKVAWNMMEEDLLYISEKHANELMDICEKEGLDAIQTMSAFLNCEINDTITGNRHHFSFHHTSAIEFLAAMYMADISASQGSLGTTFDEIDCTGYRDLLMYLAGLLKMNGTLNMKLASQLKYVFLYNMKVCPSDYTIWWNLLREGENDQSLCQMVGSIVNQADVLTVNSWDSQETTEAKMNILKQTGGAPAEVVINVHYKTAFNSCPELQNIVSLLAAAEKSKVKIYLENDFHATAETEVCDHYIVPLLKVNRLVELKGHIGRDFASNLVSAANVQSIFVRVSDIQALVKLGESMRKHRRWKVKFMPSRRWTLKYVEIFLDLKKDTEVSLIPDLKYHGTLVVKLSGISDASATWAGAVLKRLSNQYTSVILQACQITASGMEQLIGEIKGVKIKVFRVMSDYTISRDEVKHLAKKSNINIGWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAN1</accession>
    <name>A0A423SAN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004269">
        <property type="protein sequence ID" value="ROT61259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAN1"/>
    <dbReference type="STRING" id="6689.A0A423SAN1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="479" mass="54806" checksum="A899A2681B1C629F" modified="2019-05-08" version="1">MPTHILPYSPISSHTPPIPTHIHHILHAHSYPPIPTHILPYTPISSPYTPISSPYTPISSHTHHILPYTPISSHTHPYPPMPTHILPYSPISPIPPISSPYPHTHPYPSHILHTHIPTYSHSYPSISSHSHSYPHTHQYPPIPTHILHTHHILPTHTSHIHHTYSPISSIHTHILPYPLFPLISIHILPSHSYHSHTHPYPPIHTISSHTHPYPPIHTHILPYPPISSHTHPYPPIHTHILHAHSYPPILTHILHTHPILHTHLFPLISIHILPCPLISPIPTHILPYTPHILPYHLFPLISIHILPYTPISSHTPPISSHTHPYIHTHILHTHIPYPIPPIHPISSHTHPYPPIHNPYPPIHTHILPYTHPHILPYPPISSHTHPYPPIHTQYPPMPTHILPYSPISPIHTHILPYPPIPTHIHPYPPYPPISSHTHPYPPYPPYPPYPLISPYHPYPPIPTHILPYPYHPYHQSLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCU8</accession>
    <name>A0A423SCU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003880">
        <property type="protein sequence ID" value="ROT61994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCU8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="46420" checksum="20D82918DD70590D" modified="2019-05-08" version="1">MRAIEHATGKLATSKRRHISRYYFFNVKAPPSFLPFRPISPPLPPLLPSPSSPYAHGFTLSCRRTGPTVPSPLSRPLSPTYHPCLLSSFSSSACALLPSFRTSYVSPPTLPPTSPLPFLSSSLRAHSPHPCPCLLSLFPASSLSPPHSLIPSSPVAFSLSPPSPSPLSLALYSPPPSLLIPIFAGLLFSLLPSKPPSCLSLSSEREIFLYSPSPSPLSPLSPFLSPPTSPLLTRASLCPYCYSLYARRPTLLFPSHFSLSSPLPPLPLSHFSLSSPLLLSFLSLPLSSPLPLLPLFRLIFSFSSPSRSLPPSRSFSPFSPASLPSLFSPLFPTISALSSLLLPLPDLTLFALVSSSLATSLSLPLRLSFSPSPSSIALLLSFYATNSAFLFSFLFLPPPLPLDSPLPSFFLDAIPTPPSSLLRIHLTINDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCZ7</accession>
    <name>A0A423SCZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003845">
        <property type="protein sequence ID" value="ROT62076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCZ7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="50383" checksum="07D1F3175399D0AB" modified="2019-05-08" version="1">MSGKKACCRKVQANFNCNCISFLRSPLFLSLSYLSSSSSSTPYLSPLLSPRLPLTVFSPLLPTLYPSSLLLPPPLTSISISPSSSPVYLSLFSLLPFPSSPLFSLSSPILFLLLQPLISLLSVPSSCIYPFLLSSPSHHSPFSLPCLFLPFFSFLSSLFLPHCPFLPCLFLPIFPSSLLPSLSFPLLLNSSLWPHPPLVPSILCLLYPPLISPYPLTLFSLILSPPFLTLSPLFSPPLPILFLFLFYPLLVLSPFSLLPMLSLSSLLPSPFSNPYPLPSSLLPSPLPTLSSPLPLTNPYPPSHLSPLTNPYPHLHPPPNNPYPHPFISPPLPLTNPYPLPFISPPLPPYQPLSSPLHLSSPPPLPTLSSSPHLSSPPLTNPYPPPPASSARTGPPLEKFQINSPFRIHGRPVASTEASIHNPVAPQRLEFGLPKATEPTSGPHHVYCNEPMTGDIAEGERASSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDH3</accession>
    <name>A0A423SDH3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative spermatogenesis-associated protein 5-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019908</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003746">
        <property type="protein sequence ID" value="ROT62250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDH3"/>
    <dbReference type="STRING" id="6689.A0A423SDH3"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="4">
        <location>
            <begin position="135"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase AAA-type core" evidence="4">
        <location>
            <begin position="363"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT62250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="45520" checksum="EF170DD94E0D42DA" modified="2019-05-08" version="1">MSTKTKCSEKGEKKSQKKNARKRTKDSGNESLNSTLQPEITAKVVLIPKEMLQDKTLEGISRVHSLTVCIKGLAEQKGFLNHQFVTLTTKGETLPAHLLIDSKIKENVAIIKDETSKSLCEGEDVIISSQCSRLFAEEIEDVKSKFLGETEQNLKKMFDKAVDRAPCILFIDDIDILCSSRDRKGSTGIVTALLHLMDGVTGNSSRGVLVVATASDPKSLDAALRRPGRLSQDVCLQAPTEVDRKDIFEKLLYRVPSDLTDSDLHILAASTPGYVGGDLRRVIMEAIVQADGKAIDREMIQTAITAVRPAALLASNTVDREVQLSDIHGYGQLKHHLQESVNLTLCHSAIFQDCGISPPSRFFLFGPPGCGKTSLVMAIATKFHLNVIPVKRSTVLGKYFGESEQNLAKVFQKVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SER5</accession>
    <name>A0A423SER5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003560">
        <property type="protein sequence ID" value="ROT62717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SER5"/>
    <dbReference type="STRING" id="6689.A0A423SER5"/>
    <dbReference type="OrthoDB" id="6353679at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="29"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="48295" checksum="F56B6B81723B14AC" modified="2019-05-08" version="1">MEKRKCFYLKRQAPHDGQSAIIPFKKDEVLIGRSIEATHVIPHQLISRRHAVFKRESDQWTVSNLSLNGVFVNGNSIPKAEQHAINVGDIIQFGQPATFVYRFGLKEIPSRAGSSSSQQPDIKRMKSEDDRKSALANNLNLEREALEEQLKKSDAVQQRLQTERDELLLSLQSQKDDLQQKYQQEKEALEKQFSAGSVQQQVMLQEKEALAQRLKDQVSELQNRLEEERKTLEENVRKEEEQRMRILQEKEAVLHRLEEENANLERQMQEERKKLQERLQVTEEHKEELQQQVEAKENEIRVKEEQQRKAEWERQKIQEELTLEQIRLLKELERVKDALTEKEKNNSALSSELKQKEEELNERLVRSQWQLKLQRHLKRNNLCTAASPQLSFKCTGFAAHVLLSMDRVQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIF7</accession>
    <name>A0A423SIF7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_018034</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003335">
        <property type="protein sequence ID" value="ROT64048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIF7"/>
    <dbReference type="STRING" id="6689.A0A423SIF7"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043050">
        <property type="term" value="P:nematode pharyngeal pumping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14336">
        <property type="entry name" value="UBA_AID_AMPKalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000079">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000055">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049020">
        <property type="entry name" value="PRKAA1/2_AID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21147">
        <property type="entry name" value="AMPK_alpha_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="323"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="365" mass="40945" checksum="A0B2D26FCA5DF005" modified="2019-05-08" version="1">MVSKIKREITNLKLFRHPHIIKLYQVISTPTDIFMVMEYASGGELFDYIKQKGKLKESEARRFFQQIISGVDYCHRHNVVHRDLKPENLLLDHNLHVKIADFGLSNIMVDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDVWSCGIILYALLCGTLPFDDEHVPTLFKKIKSGVFQIPDYLNQSVVRCLLHMLVVDPMKRATIDDIKKHEWFQKDLPAYLFPPPHDHDSSVVDQDAITEVCDKFQVSASEVQNALLSEDQHNQLKIAYNLIVDNKRFADANALYSSIVSQNNPPIFTSTSSSKRVSDCGSVKAVSAEEGKQSISAFYTTGSPPPAPPTPSFSPSDSSSVPFRPHPERIARKYSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKB4</accession>
    <name>A0A423SKB4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytokine receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_017371</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003210">
        <property type="protein sequence ID" value="ROT64688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKB4"/>
    <dbReference type="STRING" id="6689.A0A423SKB4"/>
    <dbReference type="OrthoDB" id="6381660at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004896">
        <property type="term" value="F:cytokine receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23037">
        <property type="entry name" value="CYTOKINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23037:SF35">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019260750" evidence="10">
        <location>
            <begin position="25"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="151"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="11">
        <location>
            <begin position="438"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="597"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="713"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="792"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="602"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="794"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="869"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="894"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="926"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="979"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT64688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="988" mass="108704" checksum="EA9549B1CDD804A3" modified="2019-05-08" version="1">MKSLCHVDAWKTGLLFLLASHAASQDSRRSASILRNDFDRKVCDSPSPTSAEPVEDDLSCVSLSRRKLKCQWQTANQRDAKMYLYNYTPTWNPEEPCTCVEDWCASCLGLCCLWKVSPYDPTAPEIMIVTATATQVCNVTFNHSIIVRPDPAADVKVNQTGSYRELEVSWETPPFLLEFQPGLFYSVGYRPKNVSAYGLLEWQNETGSYHGRSATVRLASLHGGVDYEVRVRLRSGARPPPAPDGGDDGWWSTEASGNAVTLQGAPEVAPAVGVGTFEVESDADSGRRAVALQWRPVPALLHNGPGLEYRVLVTDRTNNTVRNLTENGASVRIDNLNENMRTRRYELRWPAKENLTYTAYVCTDGLSSSAPCKSNLYWKNLGSASAVNLTLEELNVTDSVTPDEVRFALSAETFAEDSSGMAWDSCIHPQQYNTQHSAPEIITNYDSTTNSVSLRWRADCAARGGVIEEVQAIWCEGRDSCVEAGNGIPRKIESDVFSGVVVLEGLREGSAYTANLRLRYRDGLSGWSSPLPFATKSSALPTWLIVTIVIVAIAVTVVVLSAGVYSRRRIEVIVREVQREIILPEGLVDQHYLSERAREQRQPQPLDSRSNKNVQAPSSQVLPLDKMHLQSLSSGDRSRAQNNIEEKKILIDQNGYVLPVFNDVGEDSQRGVHKANNIPAFTSLPPSGYVEDSYGGLTGPNPSTSGELPPIAAARKSKPPAGHVAVEPRSSNVNINSHEKEGILVKNERGASPGYVVLPTKTSRDLGVVMDGGDQGKSSTGYASLPLVDLLAPAEDRNCRGPEAESPRERGRGRRVRAEEETQEVAKEPEKRHSPKSPEGGDSPSRGQERPSEVAQSRGGRSRKSPGARGRDPGKTPQEETVAKGPERRQSPRGPRRSPRKGPRRRLLPKGPRMETVPKSPRRSPRKPDIPRTDHDTQELSRGADLVRKSLQKAAETSDNKLAMRASRRIPRNPRKPEETEEVPQEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKU1</accession>
    <name>A0A423SKU1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable U3 small nucleolar RNA-associated protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_017185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003175">
        <property type="protein sequence ID" value="ROT64868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKU1"/>
    <dbReference type="STRING" id="6689.A0A423SKU1"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT64868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="160" mass="19190" checksum="BC37CB21785ECF13" modified="2019-05-08" version="1">MSSLRNAVKTQREHRERHQPQSRQHLGALEKKKDYKKRAKDQNRKKNALKLLTKKALNKNPDEFHYHMVNSELKDGVHYERVKDEELAVGHVRQDLTYITHRRTIERKKIEKLKAQLHLLETDSEKPKNSHVLFVDDEKEGSYVCVGRRGHRWHDIMQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SND6</accession>
    <name>A0A423SND6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Exocyst complex component 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Exocyst complex component Sec10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016286</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003048">
        <property type="protein sequence ID" value="ROT65736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SND6"/>
    <dbReference type="STRING" id="6689.A0A423SND6"/>
    <dbReference type="OrthoDB" id="125856at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048625">
        <property type="entry name" value="Sec10_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20667">
        <property type="entry name" value="Sec10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec10 N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec10-like alpha-helical bundle" evidence="7">
        <location>
            <begin position="89"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="650" mass="73582" checksum="ED579F29525E2FC7" modified="2019-05-08" version="1" fragment="single">VREGRVNTGQNVAQLLDNNREAFQSFQDLDSHINSVATKVVHLGDQLESVNTPRSRAVEAQRLMNHFREFLLPGPLVSEVFTDKLKIYEAADVIQKLHLIAQELPSGKFENAKQKIGEKYDEIERSLIMEFVKAHRAGDKDRMKEIAAILSHFKGYSQCVDAFIEEAQHVGPMGVAVGALRSRDLFLEVVPLCHRSETLINEVFTNPDQVMGKFVLNIFQGQLQEYIQARLDNKSVPEMYLRNLHDLYCQTVKLCTELQRFNLGNDSQFLSKLTKSIFQRHLSSYISVETRYLREKFNLILNRYYDSKGHQKKNIQSGGINDIRRNIQDVIGTKANINIGPAAENYGGETFLSEEVAISLLQETKQAFKRCQMLSTQSDVHNNAVQIFDLLTKALLIEHVDYAIELGLQVIPGGEVRTPPEISFLEVVHQSSSMMNLLDKLFSDSLVPLIISTPKHGDCLQKKKQMGTNLEQKLDLGLDRTLSAITNYVRHVLTTEQKRTDFKPDNDDILIANVTPACQRVVRWISVVAERVRDTLDGHNVESALLELGLRLHRTILDHLMKFEYSATGAMAVICDVNEYRKCVASFKIPLVNSLFDTLHTLCKLLQVSPENLKMVCSGDQLSGLDRTVLASFIQLRSDFKTAKLGNQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSR6</accession>
    <name>A0A423SSR6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein SET</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002829">
        <property type="protein sequence ID" value="ROT67241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSR6"/>
    <dbReference type="STRING" id="6689.A0A423SSR6"/>
    <dbReference type="OrthoDB" id="19419at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000002">
        <property type="entry name" value="Testis-specific Y-encoded-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="30"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="285" mass="33233" checksum="B7F5637104BF2FA8" modified="2019-05-08" version="1">MSDTGASPAKMRKLEHPEEAHEGREYDPETQKALEEIDMCQNEIDQLNEKASEEILKVEQKYNKLRKPSFEHRSKIIQRIPNFWVTAFVNHPQISAILEEEEEECLHYLTKLDVEEFDDIKSGYRIKFYFDENPYFENDVLTKEFHLGSTGDPASKSTEVKWKDGHNLLERFRQRVQQGEKGGTGRKRNLELRSFFSWFTDHGDPSADEIAEVIKDDMWPNPLQYFLVPDIEVENGEGDDDEEELEDEEVDDSVVVVEEEIEEVDDEGVEEEEEVHGEEDGEADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STA6</accession>
    <name>A0A423STA6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin fusion degradation protein 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002810">
        <property type="protein sequence ID" value="ROT67426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STA6"/>
    <dbReference type="STRING" id="6689.A0A423STA6"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.50:FF:000001">
        <property type="entry name" value="Ubiquitin fusion degradation protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000002">
        <property type="entry name" value="ubiquitin fusion degradation protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="5">
        <location>
            <begin position="16"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="6">
        <location>
            <begin position="116"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00071119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT67426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="303" mass="34631" checksum="14B63AF15EED7281" modified="2019-05-08" version="1">MFSFNMFGEPLQPRPFNTQYRCYSVSMFPGADKQSVENGGKIIMPPSALDVLTRLNIVYPMLFKLTNRRANRNTHCGVLEFVADEGKVYIPYWMMRNLLLDEGDLIHIESVSLPVATFSKFEPQNVEFLDITNPKAVLENALRNFACLTTDDVIAINYNDRIYEMRVLEVKPGSAVSIIECDMNVEFAAPVGYQEPERMDSAAALPEDTEEEMLPEPTGFYSFQGSGNRLDGKKKNLQLPQEELLKKLPRQRGIPDYDYEIGFIKFWRKLPKVNNTENKPEEPDEFESFAGEGTSLRQAKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUA1</accession>
    <name>A0A423SUA1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Collagen alpha-2(IV) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014175</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
            <location evidence="1">Extracellular matrix</location>
            <location evidence="1">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002766">
        <property type="protein sequence ID" value="ROT67733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUA1"/>
    <dbReference type="STRING" id="6689.A0A423SUA1"/>
    <dbReference type="OrthoDB" id="10071882at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005201">
        <property type="term" value="F:extracellular matrix structural constituent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.240.10">
        <property type="entry name" value="Collagen IV, non-collagenous"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001442">
        <property type="entry name" value="Collagen_IV_NC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036954">
        <property type="entry name" value="Collagen_IV_NC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050938">
        <property type="entry name" value="Collagen_Structural_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456:SF6">
        <property type="entry name" value="COLLAGEN ALPHA-1(XXIII) CHAIN-LIKE ISOFORM X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456">
        <property type="entry name" value="SI:CH211-266K2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01413">
        <property type="entry name" value="C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51403">
        <property type="entry name" value="NC1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="7 11" id="KW-0176">Collagen</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Collagen IV NC1" evidence="10">
        <location>
            <begin position="499"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="529" mass="51851" checksum="6CA01EB070A09810" modified="2019-05-08" version="1">MGRVGAKGERGFDGAPGLEGLPGTKGELGEDGRSGDTGRRGDPGRPGSKGEPGLPGIPGRKGFDGRPGAAGRDGSKGAPGAMGVSGYKGGKGEEGDRRRGQPGVAGKQGMPGFPGQPGQPGIQGQAGRPGGRGDPGIRGDEGSQGLAGNPGQVGSPGRKGEDGRPGVAGVRGQKGEEGLMGIPGQAGTQGRPGNRGQDGRKGIPGDLGRLAISASTGTRDRGARRATRETPACEAPPETTEPTRATATKASQVYPAMQVSPASLGPRGCGGGGQGFPGPRGRVGLVGERGVPGLPGVNGKKGEMGAMGLPGTAGIRGEPGDAGLPGPHGGELDPPRPGPQGTNGAPGAKGYPGRPGERGPAGPTVGGTPAEAGEPGFQGLAGDRGFDGLPGGRGSKGFRGDEGRKGDVGRPGIPGRPGEVGTRGRIGQPGLARRAKPGQKGLGGRPGKVGRPGRSGQKGRPGEFGPDGPLGDKGLPGGSLPGLEGPPGDLGASCVEVPSLTIAIHSQTLEVPDCPVGWDSLWIGYSLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SX49</accession>
    <name>A0A423SX49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002642">
        <property type="protein sequence ID" value="ROT68713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SX49"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="44778" checksum="E687DCF297B9B434" modified="2019-05-08" version="1">MKNKARFLRLNHILNIRIFPILPFFCLPLYPLFLIPHPYSLLTYLSTLFRLCHFIYPLSFNHSLYSINFFPPLPPRLLSPPLPFPPLPSLPLSSLLLPPSSLSHSSSFFPLPSSPPLLSSSPPPLPPPPSFHPTPFSPLPSPFLPLSPPPLLPHLLPLILPSHISPPFFPSPHPPTPLSILLPPSSSTSSLFFSASPSFFYSPSSPSLPSFSIILPSSPLLLSPAFYPLILSSPFPPPIYLSSVPLFSPLLSLLSPQPQFLLPIPPLPFPLIFLSPSPPLLLPIFPPLYPSFLTLFSPLPSLPPPNLPSPYSLSLLSPTFLLSFPLTLVSPPSLPLHFLPPLISFSRLPFPPSTSSPLSSPLLSLLPFLSHFPFLPLSSTTIITTNSTSTTITTNSTSTTTATPPPHSILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZD1</accession>
    <name>A0A423SZD1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002544">
        <property type="protein sequence ID" value="ROT69620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZD1"/>
    <dbReference type="OrthoDB" id="9974725at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="134"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="26972" checksum="47A24C4E5AFEE5D1" modified="2019-05-08" version="1">MVSTCHSWMQWIWNRLCGNTPARPRLTPFRREKLLYEFNTFLDENQDGVLEECDLKLAVERLCRRYSWAPDDPRALRAKALMRDLWLSLRLHVDEDQDEKVTRAEWLSLWADVQRVSERTRLTHSKESPTIPSWMREYFHYKFLLFDVAGDGVLDEEEFVYVMAQHGAVEGVAKKSWFLMTQGRRLLRQDSFERLCEEFFLSDQPTDPGTFLAARLYFLPGEQRTGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T055</accession>
    <name>A0A423T055_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NadR/Ttd14 AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002512">
        <property type="protein sequence ID" value="ROT69849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T055"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070300">
        <property type="term" value="F:phosphatidic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045494">
        <property type="term" value="P:photoreceptor cell maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.320.10:FF:000003">
        <property type="entry name" value="Uncharacterized protein, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053227">
        <property type="entry name" value="TRPL-trafficking_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34932:SF1">
        <property type="entry name" value="TRPL TRANSLOCATION DEFECT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NadR/Ttd14 AAA" evidence="1">
        <location>
            <begin position="9"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="471" mass="53576" checksum="EB16746D6EA86DD9" modified="2019-05-08" version="1">MRVVKVYRVPETATLLLSGGIKFSDLSEDDAVVFQENLLKSMMQIENTFFSLAESCSKNCLVICDRGTMDASAFIPQERWEEIMKKNGWNPVDLRDTRYNQILHMVSAANGAEAFYSTEDHACRSENMDLAQRLDNKAAEAWVGHPYFDVIDNSTDFDTKMRRMISVVCQKLGVDTGDRLKTNARKLKFLVKGPLPDDGLFPTFQDFSVEHIYLRTNSRKMQARLRKRGKNGHHSYTHTIRKPEQLGQIVEVKTAISQRDWNNMSAQADEHHYPIYKIRRCFLHNNQYFQLDIYQKPCHQRCEGLILLETYSTLPSEELQRRLPSFLNIEAEVTGRPDYSMFNLSLRDEWGVTNKFCVNIAEEDDVSACGSCPGSGLDMHLHKPRPLAATTKLSFSHQANLDSAGKFASLSPPASEMMVNDRKDIILTSDLMIKSVEDAHNCFITNGMDVDSPINVINGPVKVTNGFFPEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1S8</accession>
    <name>A0A423T1S8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002436">
        <property type="protein sequence ID" value="ROT70375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1S8"/>
    <dbReference type="STRING" id="6689.A0A423T1S8"/>
    <dbReference type="OrthoDB" id="10015491at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000437">
        <property type="entry name" value="Beat-IIIc, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="268" mass="29672" checksum="A709A391EF693610" modified="2019-05-08" version="1" fragment="single">VAAWRPLRLKSVTVPSHQITGASVELECNYELEDDVLYSVKWYRGENEFFRYVPADSHPMQVFDLPGVSVDTALSDSRKVTLRTVSLQSSGKYKCEVSADMPSFHTESRSSEMLVVDLPDEVPTISGGQAKYHVGDEVHVNCTSARSRPAASLMWYINDDQAESRFLVEYAPENDTDGLETSRLGLRFIVGPRHFPQGELRLKCTATIAAVYWQSSEESVEGQLPQTGPALESKGVYTGDSVRFLPNAWLAAVGVVVARALLPFLPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T823</accession>
    <name>A0A423T823_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002131">
        <property type="protein sequence ID" value="ROT72591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T823"/>
    <dbReference type="OrthoDB" id="6158299at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="520" mass="57533" checksum="1DD5727559580903" modified="2019-05-08" version="1">MRQRSGPGGAQAEDQPGRVLRGERAASGRRPETESVRGLGVASQPQVLLGHDPRGDHNPVSHSTAETVNPNVASVRATTDRVFHKPPIAEKPRVTSRIARGQHGNLKGQQHLVRSYGGKQCTIVSTISRLLEEESDATTTGSSGSSEPSSPEATLKLVTPRVIRLAKQYEEGLNTNSQNIHIYNNQGSAESSPESLRHEDRNSKSYIMDEYEVTSGYNSDAISDHEYENIRVLTQGSSDVSSKHGKDESQDEEEDNYVVLRAVKENQETGNWVDVPEDQHIYSNVEFASGLMVKEVDEDTEKESETSTEEKDEKETSSTGSKSSLHGEGKNKVLETNLDALDSSASENQMLSESLRTALNVPRSRHNINLIMETDGDHMTENFEEFTLDSLELEEEHDDGDRGRGKENLPISEQRRCGDGAETKLDNKMREEAKNDGNANSASAAIVISSGQYEKFLEATGLSQKSILTPTRMFSNHRSMLKPRDIKHRNKLRAAFTTLSTLEETPGSGGVYKYWTEPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9Q6</accession>
    <name>A0A423T9Q6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ras suppressor protein 1 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002057">
        <property type="protein sequence ID" value="ROT73168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9Q6"/>
    <dbReference type="STRING" id="6689.A0A423T9Q6"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000159">
        <property type="entry name" value="Ras suppressor protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="4">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="17799" checksum="C5C4DB4EEA469E7B" modified="2019-05-08" version="1">MSKAARKALDEARETGNPELDLQEKQITSLEELPGLLSLEHITRLTLTHNRLTKVPAAIANLINLEILNLFNNIIEELPTSISSLNKLRILNVGMNRLDELPRGFGSFPVLEVLDITYNNISEGDSLPGNFFMLGEPLGGSSSRSWSTGSFGHKILFASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA82</accession>
    <name>A0A423TA82_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_008191</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002031">
        <property type="protein sequence ID" value="ROT73354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA82"/>
    <dbReference type="SMR" id="A0A423TA82"/>
    <dbReference type="STRING" id="6689.A0A423TA82"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="7">
        <location>
            <begin position="72"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT73354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="194" mass="21596" checksum="B4B01FAC7A5CAA3E" modified="2019-05-08" version="1">MGVPSLTEWPPWNTAGTPFTRRSGSAFGDWAVRKQSIPTGKVPILMVDGRPLAQSLAIARYLAKEVGLVPKDNLEAAFGDALADTIAEMMAAFYKNKMSSVTEDEKERKFNEEINPNIIRPLLGDLNKHLADRSWYSSGQMSWVDLMIAVEFGGLRKSYPKLLDDFPKVAGHVDKVMALPSISAWVKRRPDTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAC7</accession>
    <name>A0A423TAC7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6358939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1264"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1403"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1453"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1192"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1219"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1264"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1316"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1430"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1457"/>
            <end position="1469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1579" mass="172818" checksum="00D581B2E20FB265" modified="2019-05-08" version="1">MENSEMLPGSVEGGGPSAISVMVTTITTPTTLSTRETLNNMDSVRRRSSPIKLVGLGGLERQNYCCGHWFPSSKSYHRHLAEKAASDLTHEMKLIEIGMIRCTNCSMWVHMDSMSGHLRKVHGIVKVAKNTKVLPTNTGKDVMGISGETLKSGTNFVIKVSGQAGARNTNGDVSAVANSSGLKLVTTSSGSLYQKVQLQQAVNSGSSKLLLPKTGPSNSIPLVSLGPRIVMKSAVKAVAANNSVPISSGSKIIPLQSSGQVIPAARTMAGMTTVQIAGGTMLASSSGTSQTSSVPTSFVQSKKSANLNGQNFGRLIKKCATLKPKNQPVVDVQPPDSNSLEAYSKMKDRGKASISGDLNLKPAQSKKSRKQVLQPSVEPEASLLSVSPSVLKLKKKGRKLSGDTEVFAEDKVSSPKPSVNHKGYRRKLKDNPIENNTPKSSKQNTKGVRGGMKKKRGPGRPRKERVIETPDLSEIDSLFNEVDKEDAENEPYLMTKEEENIPTVELDLFTLPSLNEQVSVLLTEPQNPNFKVYASMDAIFVGDSALGDVTNQIGYVTDANNVVYVNPSHFLFPNVEDLENFVPSPIVTMKGNKIGVSPSKVCKLNSSKPVAPTMLRENKFVTSSHPREASSSEPNVERVSIEERESQFPSAKLKGSERVPTSAVSELDQTGLLSVKPLRKTNADPIRSEQTTPETVALGTASDSSFREILCPSTSDMLNSINLDNSSLRNLQTESAEKIVEKREVPVVSKVAQSEGEDLFFACKNTIEMPVNICEGDGEGDQSQDGFAVSEDSLLCDSSEKLEEKPAYTSETAKLLLSSLETITGASSENKDARDQIITDCKDWTDEVVSTQRDSVPETSELDVNLENKPAERESIMSPVEKSETCSELEAIEEEMGVDNQSESTISFVDTEPTEPRDSDRKVNTVIPRRRSRTRSADVTLGPVKPSLQNIETVNKKQQLRTRARQKSDSAVLHETHEKIQDLSTLKELRLSEIDVEKRLELAGENEKTVLDTVEEKESVLSSDTNVLAQNHIDTPVPEAVVQSGDLQDYPMTPKDSSTEIVSDLVSVESTVVMPAVVEDPVVDQSAKPASVDTGRRKVGRPRKKRRGKLLQSLDVKVLKDSVEAEPSVVPVSREEVEQNIPENVQESRPVRERRPSSKLIESLSFESTKKNKSPRAALDHQSLTNPDSDEFTDKQQEQEISQEERISRISCVPTPLLLDDKDNEVLDKDYVSPVRGADLSPSREWHGRGAKLKAQVLIQDQQAGVTDSQILPSSLETSPNPRGSPGSAGQDTVPRLQQPEEFLPSHSSPPKTHISKSPISPRSLKSPRSPSHDDREWQARRAKLKAQVMISDQQSGLSDFIVDSAEEDSAAPEIASPPVKKLKLDGSPGATRDIRSFFSVCKSPESATAEQPDSPLHVSPAIQSPPAPRSHKKRINRYSNKKSDIRSFFSVDTAGKRKLKSPPHHSPKTVRISDGVQSKSPKSSPRKQDVKAVQKLHQTYEKLEKEAFDIAAPALPSNLQNFEGFERCSRQSGLRAKSLLRLVSLLDMKRWYHLGKFPLPVDHLCDWNEEVLNSNIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDL7</accession>
    <name>A0A423TDL7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006971</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001883">
        <property type="protein sequence ID" value="ROT74522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDL7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="56091" checksum="5821DCBC6394D5FE" modified="2019-05-08" version="1" fragment="single">MHEREPCLLPLSRAISEVKENSFPSHIPSFIQPIAFSHCLRPIQEPLFSHFSSEIKEVNKFLPFAYSLSLSAFLLPLLVRSGSKKIHPLRLFPLFYQPLLLPLSRAIRGVRQKHSLRYSLSLSAFASPTSRRSGKEVRKFLPFAYSLSLSPLASPTSRPIRGVRKFPFPSPIPSLYQPLLLPLLVRSGSKLIHPLRLFPLLSAFASPTSRPIREVRKFLPFAYSLSLSAFASPTSRPIREVRKFLPFAYSPVFISLLLLPLLVRSGNLCFSHFSSDQGSKKIPPLRLFPLFISLCFSHFSFIREVRNPPLRLFPLFISLASPTSRPIREVRKFLPFAYSLSLSPFASPTSRPIREVKKFLPFAYSLSLSAFASPTSRPIREVRKSILFAYSLSLSPLASPTSRAIRGVRKNIPFAYSLSFIALCFSHFSSDQRSNLCFSHFSADQGSKKIPSLRLFPLFIAPSFSHFSSDQEVRKSIPFAYSLSLSPLASPTSRAIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFS5</accession>
    <name>A0A423TFS5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trehalose-6-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001785">
        <property type="protein sequence ID" value="ROT75322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFS5"/>
    <dbReference type="STRING" id="6689.A0A423TFS5"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000113">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000324">
        <property type="entry name" value="Putative Alpha,alpha-trehalose-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000150">
        <property type="entry name" value="Trehalose-6-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011071">
        <property type="entry name" value="PRK14501.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="827"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="897"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="907" mass="103798" checksum="A59420D146674876" modified="2019-05-08" version="1">MDVVRNPTVHRFSQSGRILLKRRLSFERQREQRQDRKQSSARQKYHETEELVYIDCSEQVLNKMIVNATSPMVVVANRLPFIVQKNAETGQFERKQCAGGLVTAVAPVVVETNGLWVGWSGQHLEDGEHDIPEANPNDRSPTAGLKSRQVIPVRLPQKQFDDYYNGCCNATFWPLFHSMPDRALFQSDKWEAYRQVNEHFAKLTVEAVVKLAETNPNSVPLVWLHDYHLMMAANSIRDRCDRLGLQIKMAFFLHIPFPSWDIMRLFPWDDELLQGILGCDSVGFHVEDYCLNFIDCCQRRLGCRVDREQMLVEHNGRTVSVHPLPISIPYDRFVSLAEKAPQVVKNNEQEQLLLGVDRLDYTKGLVHRIRAFETLLQKHPEHIEHVTFLQVAVPSRTDVKEYQELKEDLDQLIGRINGRFSTPNWSPIRYIYGCVSQEQLAAFYRDSSVAVVTPLRDGMNLVAKEFVACQVGEPGVLMLSPFAGAGTSMHEALLVNPYETDEFAEVMHRALTMPKDERELRMQQLRHREREHDVNFWLQSFLKSVDCLADNNLTPGRLLPLREEDFSQFLASYVKESSRLALLLDYDGTLAPIAPHPDLARMPEETRRVLERLAHMPDVNVAIISGRSVENVKSMIGIEGITYAGCHGFEILHPDGTMFIHPVPHEYEVQLEQLKKQLEEEVCKYGAWLEQKSSGITFHYREVPKDKQSEVMTHAQKLFQDNNIKLHQSHMAYEARPPVTWDKGRAAIYLLRTLFGLDWCDRVSTIFAGDDRTDEDAMRALQGMAVTFRITTLPNLRTAATYRLPNTDAVLTMLKWVEKRLSSRLPVTNGFRSRKTSMSSIGNNSPPHPPSSPTRRSRSNSQSPSPTEPNKQMMVMTDQVYHQLISRKNSPPRVSVSPVNTPTRSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH40</accession>
    <name>A0A423TH40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_005702</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001737">
        <property type="protein sequence ID" value="ROT75761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH40"/>
    <dbReference type="OrthoDB" id="435402at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08033">
        <property type="entry name" value="LARP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000158">
        <property type="entry name" value="La ribonucleoprotein domain family member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002344">
        <property type="entry name" value="Lupus_La"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024642">
        <property type="entry name" value="SUZ-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF140">
        <property type="entry name" value="ACHILLES, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00302">
        <property type="entry name" value="LUPUSLA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51938">
        <property type="entry name" value="SUZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="6">
        <location>
            <begin position="193"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ-C" evidence="7">
        <location>
            <begin position="562"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="428"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT75761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="605" mass="66073" checksum="ACFE29C70EFCD58E" modified="2019-05-08" version="1">MKGTNGRERRPAAGAREDWDARSGEDPQVAGLQGDARPINGLGRTLSVSVPPQWCREQGLPQSRSQAVLSWLIPCRAPPPFRRLSRGAASSGVAARRVMLSLLSRFVIGSECEESLRESRDSCASSSGPEDTDEELLNPPMPVINIDPTELAEEAIDAQRRARDAKGDNSDSLEDISNDSAIEREAEPLPPLALPGKDVCRCIVELVEYYLSDENLVKDMFLLKHVTKHREGYVSLKLLASYKKVKRLTKDWRVVAHALRASSALEMNPEETKARRRHGLPQELEEDTRPFRTIVATHIPKELANMNNIAEYFAKFGEMVSLQVHKPGGRALDEVRLVERLHPGSSATVCALVEYEKVHCARQALRAIANSAEGEMRAVEMPRKKREMGSLLGIKSQMDNESCYFSASDASEPASPVYRARHVRLMSPSSSLASSPSVSPIPLRRRGAPPSLSPESSPPSPYGHRRGPPTPCSSPEDSAAVRFLLSSDSFGPLPPRSDVPSSLPLPRRHMRAAAAPEPTWRRGVNSSSSSSPDGPAPLSPWLRRRVLARAADGSGGSALSSPSASPALRRRNDSPMPLPDNVERMPRGPDGTRGFARRSLLNAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJD9</accession>
    <name>A0A423TJD9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-terminal kinase-like protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">SCY1-like protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum. Involved in the maintenance of the Golgi apparatus morphology.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001636">
        <property type="protein sequence ID" value="ROT76596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJD9"/>
    <dbReference type="STRING" id="6689.A0A423TJD9"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="6">
        <location>
            <begin position="346"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="576"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="587"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="650"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="671"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="710"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="732"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="780"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00040972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00056114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="817" mass="90444" checksum="601AC88EC86DD9A4" modified="2019-05-08" version="1">MWSLFSRDPTSSFAYEIGEAVEHTRSVWKIHRGKKKQNGDEVSVFICEGRDGTTAQLDIAKAAVKRLKTLRHPCILTYIDSLENEKLVYLVTEPVTPLLTWLKDSALSPSHRTNAVSWGLLQVTKGLSFLNNDGKLIHYNVCGSSVFVTPGGEWKLGGVEYASSDSSMFPVKVLPELEVYNPPEKVNPSKMRTTTMWAADMWGLGCLIWEVFNGHLDESFSLKNTQKLPKNLIETYAKLVGTNPGARPNPRDVVEDLRKPGQFFRNDLIETLLFLEEIQLKDANEKHKFFANLTPKLENIPNYIATNKILPTVISAHEFSNVGSVVLSPLFKIGKLLDEAEYQRQILPTVVKLFSSSDRATRLKLLQQMESLVEYMDPKTVNDQVFPQLATGFSDSNPTIREQTVKSIMFLAPKLNYHNLNIEVLKHFARLQLKDEQGGIRTNTTVCLGKVAQYLHPDIRQKCLTSAFTRAMRDPFPPARIAGIMAIAATQQYYPLQEVVTKILPSLCHLTLDPEKSVRDAVFRVLKGFLSKVEKVSEDPSLKEVMEAEVKSAAATSQTTWTGWAVGAITSKFYKTSSGGAQPQKQTSTSSSGTVTPSTKTSSLASTPSQGRASSNTPTSAAPNEDDKSDYEDWENSEWQSMDDGLDTKPIQSRTALPKSTTVSEALADVGDMDGGDGWGDDTEEWGSLEDTQHGDSLGGGELEPESKFRSTASYNWESSGPAEDTDDFFSSLVSGNEGKSGSVSQRMTNMSLQSPTSGGWDDWDAKSPAESSNTGGNSKSDEQRRLREEKRLQRQKEIEAKRAARMGPMKLGAKKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJM8</accession>
    <name>A0A423TJM8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001623">
        <property type="protein sequence ID" value="ROT76671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJM8"/>
    <dbReference type="STRING" id="6689.A0A423TJM8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004879">
        <property type="term" value="F:nuclear receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003071">
        <property type="entry name" value="NR4A1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01285">
        <property type="entry name" value="HMRNUCRECPTR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="591" mass="62042" checksum="BC3395F9AB907B80" modified="2019-05-08" version="1">MFECASLNPVRPHSTRQPHSTQTSSLKPTILNSTILTHPTTSPPNKTSLNLTILTTPSPPPNPTILHHLNHPHSTNILSLPPSLSSSLNSSTQPPLLTTPPPSTHKSSSPHNPPTIPPSLPPPTQPSSSLNPQPPPQPTIPPHPTTSPNPTILPPPTQPSLPPSPHNLPNPTIPPSPHTSQPNHPSLTPHPPPTQPSLPHPNPPPTNPPFPPSPHNLPQPNHPSLTPHSSLQPNHPSLTPQPSLPTQPSLPHPPSPHTSPTQPSLPPPHPPPTQPSLPPPPQPSPTQPSLPHPTPPSTQPSSLTPTLPQPNHPSLPHPTTSPNPTIPPSPHPPPTQPSLPHPTPSPNPTIPLTSLTPHPPTQPSLPHPHSPNPTIPSLTPASPTQHPSLPHPTTSPNPTIPHSPHTSLNPTIPPSLTPHPPPTSLPPSLPNQPPSPNPTSSSPPNQPSSLPTPHLPQPSSLLTPQPPPTQPSLPHSLTPPHPPLHPSTPHPPPSSTLPHPTIPPSLTTLPQTPSLPHPTPSPKHPPSLTSPLPLARDNPPPPPQILLTADSCPPHLDCPRSLSWLMCGRCLPAQGGFVARGGITSWLIILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNV9</accession>
    <name>A0A423TNV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001425">
        <property type="protein sequence ID" value="ROT78146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNV9"/>
    <dbReference type="OrthoDB" id="6335033at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="27912" checksum="2D54B68272E0DBA3" modified="2019-05-08" version="1">MPHTLARRCRSFSLSQDVPVLASLPLAASPLFEEYLRRGQSDLTMYSTPWLLFLVLTAWDSRPSRAFIFPSLPQDVCNRHFSISNDTDLNKLTGEWVTVASTRKVFPCHRFSGKVEGANTTLWPKGTPETNISPLPPPPPPSGARPRQTGRSLVRGFARSRPVQELRLLLSAVHYSPREGRPQRPPGGRAEPLLPGARHGLHPDLLRHGPQPVQERPGDGLHVRRDYDLLNVDELRNEVLPTSPERNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPE0</accession>
    <name>A0A423TPE0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase-activating protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001399">
        <property type="protein sequence ID" value="ROT78324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPE0"/>
    <dbReference type="STRING" id="6689.A0A423TPE0"/>
    <dbReference type="OrthoDB" id="6345076at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057323">
        <property type="entry name" value="RHG40/28/18_ubiquitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14963">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14963:SF1">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN CONUNDRUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25442">
        <property type="entry name" value="Ubiquitin_RHG40_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="396"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="706"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="726"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="804" mass="91580" checksum="602F5881FC3FED55" modified="2019-05-08" version="1">MESFASVELEDYFNEVRTISRRTSQSNSQSEEEVRSHEGESLLQDSASAGSTLLIVANSGSGEEEALKRRVRTLNATIRRKKQRQKPDIRNFFANTDNSSTGTRSRSATPDSLDSVSPPRTPPDPHPKSWVDPYLSRSRGSLDSGNHSLVTSPSVITSPTPFADHHHHHHHHHHHHQADHHHHHHQDHLPTRSHHGVSRRYSPPSDSATRSPQWQDDRPLHMYRAPSLDMLPKVGTGHLSSGKELRRQRSYARDIARDVKSFHSKQGHRDPGAGVSVHRLRAHPPRALQGQEAATGVSVYYEDGAGSRVDSGFSPTDLGFKVIYSKPDEEFPDLVVETSRCGQTRMDWLDESDLGRLTSLALLELDILFTEHNIHHRWRKLKKRKQNKEESGVFGVRLDSLIERDRSFLEESPLETKVPLVFYKLALQLERQGLRQEGIMRVPGHRSQIEQLRRALDTHFYTSPGTADSALRNATPNDVAALIKTFLRELPQPLLTHTYMPAFYKTHRIKDMGERILALTMLILLLPSSHRDTLHAVLELCARVVAFEDENKMTLYNIAMIVAPNLFLPSNQRSKLNLRSEDKEQQLNYEMTYANVTTQLTQMMIKYRDVLWTVPQRLVSQIRRIYQAEALKQSNYTPMRRLLTRKSKETIQRPIENEVDYQEGVLRVSAPQFNKCNYPVKLDPLMTAKDLLTRFIEELTVLPENPRRVEGRREQQYKRGSGGNGSPPSTAPSSVSSPQFYACLLTGSLKKAVEQHALHERGGNIGDRRLDSKAKLLTIYQDNPNAEFIVKCHHHGGQTSRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPN0</accession>
    <name>A0A423TPN0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">60S ribosome subunit biogenesis protein NIP7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002898</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NIP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001388">
        <property type="protein sequence ID" value="ROT78393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPN0"/>
    <dbReference type="STRING" id="6689.A0A423TPN0"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="95"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="20462" checksum="3EB8F0BD5613BA80" modified="2019-05-08" version="1">MRTLSDDETALVFTKLSKYIGSNIKSLLDRSDGLYCFRLHKGRVYYVKEDVMKVAALLPRENLVSMGVCFGKITKGKKFLLNITALEFLSPYCQHKVWVKEASEQNFMYGNHIYKSGLFRISDNTPKYAGVVVYTHNDIPMGFGVAAKSTSECRHANPMDIICFHQADIGEYIRNEDTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRA5</accession>
    <name>A0A423TRA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative basic proline-rich protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_002298</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001306">
        <property type="protein sequence ID" value="ROT78990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6157510at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033562">
        <property type="entry name" value="PLPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406:SF41">
        <property type="entry name" value="BRUMMER, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1210"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1253"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1335"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1369"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1424"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="1036"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="490"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="1040"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="1069"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="200"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="400"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="743"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="929"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1455" mass="160497" checksum="D6E50D780AB8F515" modified="2019-05-08" version="1">MDRRGSYRDETAVTNGRRGSSRDVLQDTERRPSIRDELTVEKSRRSSFRDVPQESERRASIRDEVPDTERRGSFRDANERRASYNKSASQDVERRGSFRDVPQEAERRGSFRNDAATDKRRRSSSREVSLEAERRGVQGAVVHSKESDVVHSRTPHRKQNGVAHSGTPHRKQNGVAHSGTPHRKQNGVAHSGTPHRKERRGSFRDAPQETERRGSFRDAPQETERRGSFRDAPQETERRGSFRDAPQEAERRGSFRDVPQEAERRGSFRDVPQEAERRGSFRDDIMVDTRRLSSSSGSFRDVKERRASYNRDVSQDEERRDSFAPDGERRRSIRDEILEAERAERELEERLDGDHSRPVSRSSMLRSPIPIIDIQEPQPDNPTTPSESENESELDAEFNLEEHSRSLEYRKSLSDILPDTQAMPQLVTYQQVLDEDNERPRSRSSVGSDAEGEQREPARDWIKPPTDRGPRLSIGQGMFNLLVRRFSSAGTDDATPADQSTKAQEEEVSRSPRGSVSNLDVRKLSRGSAVDQEVSRSPRGSIGAQVSKSPRGSFADQEVSRSPRGSIGEQVSKSPRGSFADLEVSRSPRGSIGEQVSKSPRGSFADQEVSRSPRGSIGEQFSKSPRGSFADQEVSRSPRGSIGEQVSKSPRGSFADQEVSRSPRGSIGEQVSKSPRGSFADQEVSRSPRGSIGEQVSKSPRGSFVDQEASRSQRGSFGEGMDKSPDSVMDQETYWSPRGSIGEQESLSPEDSTRGQISSSPRVSIGEQGSKSPRGSFVDHEVSRSPRGSIGNVGVSLSPRGSIGMQVSKSPRGSFVDNEVSRSPRGSIGEQISKSPRGSFVDNGVSRSPRGSIGEQVSKSPRGSFVEQEVSRSPRGSIPTLSQKSPRGSFAEQEASRSPRGSTAGEVASRKSSTFRDSHENLETDLPEEDRYQDHVSHDQRDSISHEDPGFSLTASLTSFIRRLSGGTIVTDIISNTDNSLQEIDTSHTNGKVHHETPSKENLPLETMTANIDTLEVQPTRDTEPPKKAVQDITTVTFCGCGFLGVYLVGAATYLQDNVPSLLRGHLAGSSVGSLIATCVACDVPLQILRENLLSTARMSRKYILGSFNPFFSLEDSLLQCTLRALPEDAHIRASGRVFLSLTRVSTLANEIVSEFNSRDELIQALICCCFLPGLSGYSVPSFRGRSFRPPTSLSSPSNRSRSFLSRYPLSLSLFLSLLNAFFAHLLFSCLFLFSLVSLFMLSVCLSGWSSSFLLFLLSLSLFSVSLSLSSSLLSFSSSLSRLISLSLSCSSPYLTLSSSSLPLSLLPPFHPFFISFRASTTPLPNHSLALLLPLSLSAFFFFFPFFFLLLFFSLLLSSPLPTPSSLPLFVFSLSFLSFLSSFPPSFFSALPPPLPSSLSPRFLLRSCSPLFLSHPSPLASFPLPPLSLSSSALLLFSTFPTLLPSRYRAALPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRB5</accession>
    <name>A0A423TRB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001310">
        <property type="protein sequence ID" value="ROT78963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRB5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="554"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="594"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="650" mass="70252" checksum="B45F93D7CBCE7247" modified="2019-05-08" version="1">MLNISSPARPPPPPAIPPSHPLPPTLATPARPRPSPPIPSPPPSAIPPIRPRHPHPPLSTPIHPPAPPIARPLAANHVQNLIPPHSPPPPVRHSRPNRRESRVVVFSLTFKNTIRVTSCLVAPGGPLEAPATLGSPTTRLEAPATPWKPPATLESPATLGKPRANPLEGPGDPLEAPGDPLEARRPLKPRRPLEAPATPWKPRRPLGSPGEPRWKPTATPWKAPGDPLEAPATRWKAHGDPLEAPATLWKPRATPGSPGDPLEAPATRWKPPLGDPWKSPGDPLEPRRPLGSPPDPSDRWKPPATRWKPRRPVEARRTRWKPRRPPRRPVGSPSNPLEAPATVGSPGDPLEAPDPSHPLEARPPRPTRWKPGDPFGKPHRTVGSPATRWKPRRPVESPRPVEAPAMEAPARPRRRRWKPRRPVGSPGGPEAPADPWKPPRWKPRDPLERRRCDRWKPGRPVGSPGDPLEAPDAVTRWNPCWKPPRPRGSPGDPLEPRREPFGKPRRPLGKPLEARRPLEAPGDPLEAPATPWKPGPVGSPGDPLEAREARRPVGSPGDPFGSPGDPLEAPATPWKRPPGDPLESPGDAVGSPIGPLDSLGSPGDPLDPLEGPGGWKPGDPLEAPATRWKPPATRWKPRAVGSPLEAPATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRE6</accession>
    <name>A0A423TRE6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001304">
        <property type="protein sequence ID" value="ROT79011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRE6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031983">
        <property type="entry name" value="DUF4786"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16027">
        <property type="entry name" value="DUF4786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019492091" evidence="2">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="13520" checksum="8759E25D6EBFB35A" modified="2019-05-08" version="1" fragment="single">MQTRPSVYRCALLGLRFRLSVCLALVLLGAASSAAPLSSSGALQVLQQLGLDRGTGPAPSIVQGQGKRRGDSPIYYIKLPPLPYYFVNNNIQETVEEEEEEVVEQAVPQPQLPQSQAEASSPLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRU7</accession>
    <name>A0A423TRU7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001282">
        <property type="protein sequence ID" value="ROT79161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRU7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="42051" checksum="34050B72D433BB77" modified="2019-05-08" version="1">MQANPPPSLPLFTRHVPALLRPFGPGTGCAIGRKAACFTVSPPPLLLTFLLFSPTPPPTPPSPLLPPPSSSSFPLPLLPTPPHPPFLSAAQVGDSWHRLAIGRKAACFTVSPLLSSSHPPLLSPLLLHSSLPTLPSFLLLLPLPSFPLLPTPHSSQLAQCNRTSRPSPFSPLPLPHLLLSPLSTFYPSSFLSLLLYSFIPPPLSSQSFSKFPYIPLLLPLPFSLSLSSYLPSFPIPLPPSSFPSSSPVSLYLSVFSSSFSPFLSSLPSSLFLPILLSFIYLSSPIFYPLLRLFPFFQIYFSFDQPLTRPSPSPLPFFFFSFFSPLSSLHLPFSFPSFLLSFPSPLSSPFPSLPPLLLPSLPFASLTPFSLSLPPSLSPSLPSLSPPSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXQ1</accession>
    <name>A0A423TXQ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001001">
        <property type="protein sequence ID" value="ROT81234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXQ1"/>
    <dbReference type="OrthoDB" id="6352060at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.30">
        <property type="entry name" value="Haemolymph juvenile hormone binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038606">
        <property type="entry name" value="To_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="13400" checksum="B73FE77FD7F03F23" modified="2019-05-08" version="1">MSLRVPLLTALTQDYSLTGVHDGTPTEAAGTGQLKFTNFDLKVDFKADSYSLDPMSVCMQPGSFSIDLGVESIESNLEGAGEVNDDINTEGPALLEGVEAQINARSDDIEQLVNGALCVQLEYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZR9</accession>
    <name>A0A423TZR9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Paramyosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_024895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000903">
        <property type="protein sequence ID" value="ROT81950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZR9"/>
    <dbReference type="STRING" id="6689.A0A423TZR9"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="7" id="KW-0518">Myosin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="12">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT81950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="126" mass="14665" checksum="60E6E89FF6F29A19" modified="2019-05-08" version="1">MRKGLEVTYKDLHTRLEESEAAALKTGKKAVSDLEARIRDLEASLDDETRGYADAQKNLRKCERRIKELAFQSDEDKKNHDRMQDLVEKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U084</accession>
    <name>A0A423U084_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase</fullName>
            <ecNumber evidence="4">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024723</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000883">
        <property type="protein sequence ID" value="ROT82101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U084"/>
    <dbReference type="STRING" id="6689.A0A423U084"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056452">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF20">
        <property type="entry name" value="DNA TOPOISOMERASE 3-BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23546">
        <property type="entry name" value="Zn_ribbon_TOP3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Topo IA-type catalytic" evidence="5">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="35787" checksum="59E2F2F9464B7326" modified="2019-05-08" version="1" fragment="single">MRCADRNQLDHDSWRLYEYITKHFIGTLMPDCIYLSTTICISIGAENFSVNGKQLLDPGFTKVMDWLALQDEEKLPDVKSGDEFAVLETRLSERQTSPPDYLTEAELISLMEKHGIGTDASIPVHINNICQRNYVQVSSGRRLVPTSLGIVLVHGYQKIDPDLVLPTMRSAVEEQLNLIALGKADFNAVLRHTLEIFQLKFQYFVNNIGGMDELCGKCRRYIKLVETKPIRLHCVNCDETFAVPQNGIIREFHENRCPLDDYQLLMWSGGAKGKSFTFCPYCYNNPPFPDMAKASGCNLCSHPTCEYSRDNTGVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U436</accession>
    <name>A0A423U436_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000683">
        <property type="protein sequence ID" value="ROT83461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U436"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="47721" checksum="FAE61B2D374CB110" modified="2019-05-08" version="1">MLPTHSSGSPSFLPLPLSSSASSSSPPPTFFSLSSLLSSPSLPSFLSSPSFSLFTSPSLFFLPPLFTFLPSHPSLSPLLLFLLTSLIPPLSLSFPSFSLFASPFSTLSLPPLSFSIPLSSPPPPLPPPLSPPPSPPSPATPFSPSLSLLPSFSLLPLSSLLSFLTLPFSTSLPPSLTSPLPSLPYFPLSLHPPFPLFPLFPSSLPPAPLPPLSGLTLSPSSTAPPIPPPSSSPAACAPSSPPSLLLPAFSLSPLLPLSLLFSLSPSTLPIFSRPSLSLQPSPRISPLPSPPPPPIIPLTCPFVPFLLLFLQSPPSPLCLSPHSPPSISLSSSRLLPSSPSLLPFPPSSHLPSPPPFFPSLPFLSPPLPSCLPLFPKPSPPLTLPLSFPPPFSLPLLSFPSSFRLPSLLSFLYFPRLFNFLLLLLLSPSAFLLPFPLHPTHLFLSVSLRIFPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5X6</accession>
    <name>A0A423U5X6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Thioredoxin-related transmembrane protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_022700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000591">
        <property type="protein sequence ID" value="ROT84124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5X6"/>
    <dbReference type="STRING" id="6689.A0A423U5X6"/>
    <dbReference type="OrthoDB" id="7869097at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052454">
        <property type="entry name" value="TMX_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46107">
        <property type="entry name" value="DUMPY: SHORTER THAN WILD-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46107:SF3">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT84124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="231" mass="25698" checksum="1C3BA4D72CAFA199" modified="2019-05-08" version="1">MSSPLYLFCYYFYSFAPWCPACKALKPIWQDFATWSDDLGISVGQVDVTNSPGLSGRFMVTALPTIYHVKDGKFRQYRGSRDKDEFMSFVEERRWREVEEVPAWKSPASFQMSVVSQFFKLSMVLRGVHSVLVEDYLLPTWGSYLVFALATILVGALLGLILVCIIDFVFPPKAPGPAPVVTSAGLKADDDEEDLVEDTKAKSSLCIPPPLLPASPTQSPFVPPFTTTPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7F4</accession>
    <name>A0A423U7F4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000520">
        <property type="protein sequence ID" value="ROT84616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7F4"/>
    <dbReference type="STRING" id="6689.A0A423U7F4"/>
    <dbReference type="OrthoDB" id="1702031at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="697" mass="74196" checksum="993B5AD18E13D8B0" modified="2019-05-08" version="1">MPFLHQHGTAAASDPADLAVPRARRGPRSVLNSTASTKPRVEPSKGTPPSEGGGAKGDQGAELQKVVEKKEAVECPKDVGSGVAIDEGESTGESDFESDEDCDTSIVKGDGGETDEEDESTEESKKGTGKENGTESGGGKGGKGESGVKDETKANKTKTTNETLNGVKNESKSDVKNGTLSRPKVKPGSGKNRTGDSDSSDIESTEESDFEQTTEDEEKERAKSEKKAKQAEEKQNKGKTTEDGTTGNRSMKVADQAKKTETTKGGENDEKVKEVADETNESGTTKDGENDEKVNEVADETNESGTTKDDENDDKVNEVADETNESGTTKDGENDEKMNEVADETNESGTTKDGENDEKVNKVADETNESGTTKDGENDEKMNEVADETNESGTTKDGENDDKVNKVADETNESGTTKDGENDDKVNEVADETNESGTTKDGENDEKVNKVADETNESGTTKDGENDEKVNMADETNESGTTKDGENDEVKKMADETNESGTTEDEENDEKMKEVADKTTKNGENDEKICVISLRPCPNPPSLSPSHIPLPSSILPSLLPGLLPSSPPPFLIPIPLPSSHSSSLPPYSLHPTPSHSPCSLPLCLVDISHSHLYPPLPHPFLIPLVDVIYISPHSSPLIPPLTSTPPSPLIPPSSPHLLIPSQNPLPLTAPSLNPLPFTPSPPPLITTSLYPLPSPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7Z3</accession>
    <name>A0A423U7Z3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative enoyl-CoA delta isomerase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_021970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000490">
        <property type="protein sequence ID" value="ROT84833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7Z3"/>
    <dbReference type="STRING" id="6689.A0A423U7Z3"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000084">
        <property type="entry name" value="Enoyl-CoA delta isomerase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="272" mass="29810" checksum="9681C79B9054A0DE" modified="2019-05-08" version="1">MATNQEPDLVEVVKDGIYIIRFNRPKRKNAFNDKIMLGLGPALERAASNPDAVIAVVTGTGDYFTSGNDLSNFTKGASGSGGASDKKGEVNLELLAQATVGSFNRLVKAFIDFPKPLVAIVNGPAVGIGVTMLGLCDIVYATNRAVFHTPFVSLAQAPEGCSSYLFPRIMGQGKAAEMLVFGKKMNAEEACKLGLVTEVFPDEHMDQVWPRLHQWAKLPPIAMMRAKGLIRSHLKDKLHEVNDLECKRLAESWTTEEFMTSLMKFFTKKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTA8</accession>
    <name>A0A3R7LTA8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_019873</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003730">
        <property type="protein sequence ID" value="ROT62328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTA8"/>
    <dbReference type="OrthoDB" id="6350208at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF13">
        <property type="entry name" value="HEAT SHOCK PROTEIN 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00299">
        <property type="entry name" value="ACRYSTALLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="479"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="103"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="347"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="578"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT62328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="641" mass="71807" checksum="2A6E68DD8E09B480" modified="2019-04-10" version="1">MAPVPHSYDLKVSAREASPCQCEEPSKRRWDVALPISRRGSFFQDSFFSDVHDEFDATVRRVLARWRDTDFSLRDCWDDNCRYSDILKRYRQLRSLNLKEEDQAVTVTSDTSGHKEDQSHQKTTVVPIKLEEAESSSASKTSDKNEASSVENTSEESNCSRKPICETIKKESINIPSRAKEVPTVNSVQPRSVEIDISKECINDDVCGVEKQGNVKTTERTNPDITDESNLVCKELDSTGLEISRQRFWDEFLPITRRGSFFQDSFFSDMHTKFDAAIRKVLNRWSSNELEWTDTWDDVGFHYKDILERYRELRSRHLEENLAVTVTSDKTGHKKCQRKEAVVPVQLESKEEEAVRAGHGGSPADVLVSPDEAEKKGSSADLLSPTSDDDDEEGYTFIVRRPGNSYGVSFGDDEDSHAWKRESSAGDSRSKCALKSSGLDCESRNLAIVRKGLFADDCCFENVRRNYSQAVRQVLEKANEWSCGSDALDKYRKLRQQKIVMDVLDFLGGDVTVRLVEGKELLVEGQAERQDGGRVSRVSFVRRFALPELVERDAVSCVLSSDGILTIVSEKKGDALASATAGVPSRMESYPGMGRGGGLKGAGDFEDSGSQDSEPVPASSISCAISTSLHWFPESCNFYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVX6</accession>
    <name>A0A3R7LVX6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016084</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003015">
        <property type="protein sequence ID" value="ROT65928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVX6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="43531" checksum="3DFF5EC9EC3F20BA" modified="2019-04-10" version="1">MLGPPFTPEALVWHCLPHALGAFRSRRGDRSSRTPTEPRARSKEERAAVGGGRVRRRWRGEPRCAEARLRLAKGARPKPPKRQQTGRRSTERQQYTAALASLAHALHPWASFCVSDLFSTSFFLLVLSSSHLFFFPPLSSSFLFFLPLIYSSFPLFLLLSSFLFFLPLIYSSFPLFLLPSPSRSLSLSPLFFSPSFFLLLLLFLPPIYFSFPSFSFLLLLALFLPTLYSSFPLFLPPPSPSLSPSYLFLFSPLSSSFFSFSISSPLSFFLLLLLLFYLLPYIFFFPTFFFQLSLLSHLPLPLLPSITPSFVSLSISLRRPPLFLSFALPPPFHLSLFPLPPQLYPHTPFSPFPSHSPLSRTSFFTLPLQSTVSIPSPRSFSSSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVZ6</accession>
    <name>A0A3R7LVZ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">116 kDa U5 small nuclear ribonucleoprotein component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">U5 snRNP-specific protein, 116 kDa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_016050</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003012">
        <property type="protein sequence ID" value="ROT65958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVZ6"/>
    <dbReference type="STRING" id="6689.A0A3R7LVZ6"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04098">
        <property type="entry name" value="eEF2_C_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04090">
        <property type="entry name" value="EF2_II_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01683">
        <property type="entry name" value="EF2_IV_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16264">
        <property type="entry name" value="snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04167">
        <property type="entry name" value="Snu114p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000004">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000029">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000009">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000574">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1430.10:FF:000001">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031950">
        <property type="entry name" value="EFTUD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044121">
        <property type="entry name" value="Snu114_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035655">
        <property type="entry name" value="U5-116kDa_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF6">
        <property type="entry name" value="116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16004">
        <property type="entry name" value="EFTUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="73"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT65958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="919" mass="104005" checksum="5664480C1722DDFC" modified="2019-04-10" version="1">MAVVLHEDKQYYPSAADVYGPEVETIVQEEDAQPLTQPIIQPVKVKKFSHVEKDLPATSYNLEFLADLMDNPTLVRNVSLVGHLHHGKSTFIDCLISQTHPEFRSKEDVPVRYTDTLFTEGERGLSIKATPITLVMQDVRNKSYLMNIFDTPGHVNFSDEVTAAMRISDGVVLFIDAAEGVMLNTQRLLKHAVQEHLAITVCINKIDRLILELKLPPQDAYYKLRHIVEEVNSLLLQYTDQENPKTISPLLGNVCFASSQYALCFTLKSFAKLYAQHYGYDLPLEDFARRLWGDIYFNPRTRKFTKKPPTSTSQRSFVEFILEPLYKIFAHIVGDVDTHLLPLMDELGIHMSKEEQRMNIRPLLKLFMTKCIGDFEGFVDMCVQHIPSPQANGKEKVETTYTGPLDVELAENMMACDPEGALVVHTTKQYPNEDATAFHVFGRVLSGTLHANQDVRVLGEKYTLMDEEDSRILTVGRLWVHEGRYSIEVNAVPAGNWVLIEGIDEPIVKTATITDLPPSSELHIFRPLKFNTQSVIKIAVEPVNPSELPKMLDGLRKVNKSYPLLSNKVEESGEHIILGTGELYLDCVMHDLRKMYSEIDIKVADPVVSFCETVVDTSSLKCFAETPNKRNKITMIAEPLERGLAEDIEGEVVQINWDRRRLGEFFQTRYDWDVLAARSIWSFGPDHSGPNILVDDTLPSEVDKNLLSSVRDSIVQGFQWGTREGPLCEEPIRNCKFKILDAVIAEEPLHRGGGQVIPTARRVAYSAFLMATPRLMEPYYFVEIQAPADCVSSVYTVLTKRRGHVTQDAPVAGSPLYTIKAFIPAIDSFGFETDLRMHTQGQAFCLSVFHHWQIVPGDPLDKSIVIRPLEPQPATHLAREFMIKTRRRKGLSEDVSINKFFDDPMLLELARQDVTLNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LY99</accession>
    <name>A0A3R7LY99_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002931">
        <property type="protein sequence ID" value="ROT66462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LY99"/>
    <dbReference type="OrthoDB" id="6374727at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.20">
        <property type="entry name" value="Pheromone/general odorant binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21250" checksum="1618958F95EE6FF6" modified="2019-04-10" version="1">MLHDPELPGQGGGHSHTSLAVYKADETLDEVPTSRAVIIMKSLATLFTAALLLAFAGAKEHYVHQVCAGAGPECLSKASTCGEKMKPNAEYKQQFHEAYLLCEAKSDESKDESPESSEDSLDDEFGEHSKCIMEETGFMTGWEMNRDTIKAYISTLNLSEELKTALDTAADTCENPTVGDVFAFDKCLLAACIEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M058</accession>
    <name>A0A3R7M058_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002726">
        <property type="protein sequence ID" value="ROT68019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M058"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="44990" checksum="86F0E4A7D428F4C5" modified="2019-04-10" version="1">MSECDEEKIGCEFNSSTITAPGMNMFGLPCKHRQPDGHKGLASQSEASIAGVVYQARAVNPRGEQHDARANAEMTCDDIARGENHPLGLSKRPYINIKSFYRKMNHVLHSHSPATRSRRSCMMPPIPDHVGMRSRAPPPPPPLRLPSQMWLRVKIAVECCRCAWLVYVWPLLPPPSLALSGAPPISSFGPSVPSTSLFIPAPSLFLHLLFIPGLFIPVHLLYVLPPSLFLLFHLPLYVLTLVLTRPLPLYSAPSTSPLVIWLLPPPILVTSLPLLFFSLLVLPLPSPRSCPFHPPLFPPLPLHPSIHLLLPPFIPAPSISLFIPAPSTSPSFLNLPPPAPSTSLFIPAPSTSPSFLPLPSLSYPFHLPLYPCPFHLHPSSLPLPSPLSLLQPLPSSPPLPSSSFLPIFKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6F7</accession>
    <name>A0A3R7M6F7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008317</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002046">
        <property type="protein sequence ID" value="ROT73264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6F7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018674965" evidence="2">
        <location>
            <begin position="31"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="39893" checksum="5828DBF29AC73A5E" modified="2019-04-10" version="1">MTCHGTLPTGYAMTLPWRVLCCLPLHFVCSSPVAIGHNPGHFSLSDTRRHLLPVTINHNLPSDSPSNQPFIQILPLSSSPSPMISHHHHPLPHPLPLSLFSLSPSLTHEARGRDPQHTRPTAQRPQGARRSTGGEWEGSNGASYRLAKEQLNARIPKTSLRVPASIPNILFAFTIFYFPSRFTLPTPLPQLHPPHPSTSTLPTSPPPPPPIPPPSPLSTSPLPQPPPSPPPHPSPPTSTPSPLHLPTSPNLHPPPISPNLHPPHLPKPPPSPPPPTSPSPSPTSTLPPPQPPPSPSPNLHPPISPNLHLPTSPNSTLPLPQPPPPISPNLHPPTSPNLHPPQTSTLPTGNLHLPPPLKVLANRKHPREILAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MB62</accession>
    <name>A0A3R7MB62_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002229">
        <property type="protein sequence ID" value="ROT71912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MB62"/>
    <dbReference type="STRING" id="6689.A0A3R7MB62"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="446" mass="48519" checksum="47EB2B7A0A3A09C8" modified="2019-04-10" version="1">MLPFLFPFSLLISYHSPFPFHVYLIFFFLLLPLLPLLPPLSLSFFISLFFSLSLYPSSSLSPFLSLSFFLSPSFSIPFFYSLSFCQSLSFSFSTPFSSSLFFYPSPSPSSSPSSNPSLSPSLSFFSLLFSFSLSLSSFFHNLSLSLSLSFFSSSFSLSLSPLFLSPPPSPSPYPSLSSPPPSPSPYPSLSSPPPLPLPLPPYPYPSLLLFLPLSLSFFSSLSLSLSFFSSLSLPSFLLLLPHSIPYPSLSSPPPYPFPISSLSSPPPSPYPSLSLLPIPFPISLFLSPPPSPYPSLPSPPPFPYQSPSHFTGTTTWPLAALHRAGHLREVIIPRAKEGHLDITAAVPYPLPLNSISPPSTLPLPPPPPFNPSLSPTPLPIPSTLPLTTNPFPPYPLLFIIPPLSPLPLTLPSHLPPTTYPSSLPYPFPLTLPTPLPSSNPQPYPYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBI9</accession>
    <name>A0A3R7MBI9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isocitrate dehydrogenase [NAD] subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001407">
        <property type="protein sequence ID" value="ROT78263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBI9"/>
    <dbReference type="STRING" id="6689.A0A3R7MBI9"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="7">
        <location>
            <begin position="50"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT78263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="41608" checksum="2C6F60E2242CC1DE" modified="2019-04-10" version="1">MAAIGRKALLSINTLRPLVACFHTARGLHGVAPLTSAIQAPVSKPEGRTTATLIPGDGVGPELCQVVLDVFQNAGVPVDFEEHYLTELYARRSESLDDVVDSIKRNRLCLKGILATPDHSSDGELKTLNMKLRDELDLYANVVHVKSLDGINVRHKNIDMVVIREQTEGEYSALEHESVAGVVECLKIMTRQKCRRIAKFAFDYATKHGRKKVTAVHKANIMKLGDGLFLKQCEEVAAMYPNIEFSNMIVDNCTMQMVSNPHQFDVLVLPNLYGNIIDNLAAGLVGGAGVVAGASYSSDSVVFEPGARHTFSEAVGKNVANPTAMLLASANMLNHINLQYYGDMIRNSVDRVIRVGKVRTKDMGGFATTTAFANAVIANLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD77</accession>
    <name>A0A3R7MD77_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF243 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002046">
        <property type="protein sequence ID" value="ROT73253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD77"/>
    <dbReference type="OrthoDB" id="6378257at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004145">
        <property type="entry name" value="DUF243"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03103">
        <property type="entry name" value="DUF243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00690">
        <property type="entry name" value="DM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF243" evidence="2">
        <location>
            <begin position="170"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="38411" checksum="3D32E73BE3E2E0BD" modified="2019-04-10" version="1">MITPRVTIEQSILYSTQHDTTPPFSFFSKVLLAVLLTLGSGAPQGYTLDKPSRPGLTTGPGFSAGVGIASGTGISTGSGFTTGSGLTSGGVSAGVSFTAGSGGLSHGSGGFALGSGLTSGAGVSTGTGRLTDVGSAGGLIGDGFPSITDAIAAGCREGEILHVDGTCVVPEVSRKVFVVDVPQQQQLSGPPPSVPPPKVDHNILFVRLPEEGLAPEPIVVPPPRQNNIVYVLNKQNEQAQRVIEVEAPPPSEPEIYFVNYDDGENPTLPGGIDLLTALGSAAETGGEVIGALGGDGITGGIAGVSGLQGGVTGQGVIGGSGLIDGVVGGAGQGGISGVSGLVGVTGSGQGAFGGAVGTNIGTNGGFGITVGSSGGQVRPGSQGNLVTPSGLYSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEU4</accession>
    <name>A0A3R7MEU4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001888">
        <property type="protein sequence ID" value="ROT74480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEU4"/>
    <dbReference type="OrthoDB" id="6375777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="594" mass="64876" checksum="F376F390A85C0829" modified="2019-04-10" version="1" fragment="single">NTYSACNYYIYNHASNHTSNYHNFYNHASIYYFHDFYNHSSNYHDFYNHASNHHNIYNHASNHNFYNHASIYNHANYHDFYNHTSNHHNFYNHASNHHNFYLLQPRQQPHKLLQPRQQPPQLLHHASAQPHNFYNHATTQLLQPRQQPPQLLQPRQQPPQLLQPRQQPPQLLQPRQATTTTSFYNHGTPPQTSTTTPATTTTSTTTPATTTTSTTTPATTTTSTTTTTTASPHTTATTAATTPTAEEAGSQDQVEWLILSDDDPAPSEVAAAPLVPPEVVISSGIGFGSSNNNNNNMVKNDAALGTRVEDAASLASDDVVSVVEVVMPTHEGAAAGSDVGAVEDDQVMSVVEVIMPGAEGSVAEEGSDSAGTTAAEGNAAENTLKDAAAMEDEIGMETDSVASVVEVIMPGEGGTDVGDQNGDPSADVAGIVEVIMPTDGDKAPMDVVPEDLDNAPVTEAIEAATEPNKETDAEGDKPTVAEEPESNDQGTEAEDEIIPLTPEEECGGAFLKVRENIICGSRLRGESVFEDKNFEDERFRDVERVSIRTMENASRRLRFSFDYATDCPVPKTTTTPAPVRKTVTLLQYLLGWYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFC5</accession>
    <name>A0A3R7MFC5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001041">
        <property type="protein sequence ID" value="ROT80995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFC5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="505" mass="54985" checksum="8602A508C63954B4" modified="2019-04-10" version="1">MSCLLIFLFVYAVSPFFGLVFSTSVPFSSLLLPVSSHLRSSSSPSLPPFLPFPKSPLSLFLLLSRFQSPLPLFLPLSLPQSLLSFSSSLSLPFHGLLFFSFPSLSLFSTVSFSSPPFPQSPLPLSLFQSPLPFFPPLSRFHSLLSLSSVSTVSSPSLLPLSFSSVSSPSLPFPQFPFPLFLRLSLFQPPPLPLPPCCKTLDRHSMHNGRMFFFPLTLPSFIFSFFSPSLLPSSFHSLLSLSSSFIFFSFSPFPLSLLLLPLSSPSFLSLSSPITFLHSFFSSFFSFYLSQLSPSSPFALSLLTTLFIFFLLSISCSLSFIHITLSHYAVSTPSLPPLPSHTPPSPTMLFSPTPDPSSHTSPHILPSSSLPLPLSAPSSPQYPPLLNPQYPPLPWILVLLPSPLSAPSPQYPPSLDPRPSLPSLVSTLPWILVLLPSVSTLPSSSFYPQYPPLPWILVLLPPPLSPLLPLSIHPFPGSSSFLPSPPSLPLLPSVFSPSLDPLSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGV7</accession>
    <name>A0A3R7MGV7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LolA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000983">
        <property type="protein sequence ID" value="ROT81399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGV7"/>
    <dbReference type="OrthoDB" id="6345442at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058831">
        <property type="entry name" value="LolA-like_dom_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902:SF1">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25898">
        <property type="entry name" value="LolA_2nd_metazoa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018673930" description="LolA-like domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="LolA-like" evidence="2">
        <location>
            <begin position="265"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="718" mass="80958" checksum="55AEDE0610D5ABBA" modified="2019-04-10" version="1">MVRPGMVRMVAAIVTVLATVDASQRKTQYCDVIPDALDPPPHPEVTNQYTCSMEVVSDAPENPGDPNMRLEMFVKEVYDEPGNMFSMQIASKYYVERYILNWNTKQMLFIHTSKNSNEVRECVPRPLSEGVIFFPPILGSGQNLSVSHIVGPGAVLGILNWNETHYKGEYSFRGMTADRWDWCGLKEFENETGSHNISMATYWSSSKWSMPVMPTAEASIPLGWEVEVHEPQGGGSHGYYTVETLVHNIMDFSPGVVDYEEFRIPEGLFCEGMVPLEGHPFPDFSKDRLFTFSMEMRDSRVKDFTWADGWYDFEKQLYRIDHEIMSTPRERITATEVFDFNDGLAFTFGKKIARCRITIVNDTRTDWSDITGIGHLWADSPNAFFGSDLVNYTYYGRRFERYMEGDEWRASRSDWPLDVTGGNNQMLWQWTFANKNVTTVTSLGDHLYVERQVPIGLSVTALHDFQTSFGHVAKGSSFEYQIYDFNLESSAKFDLYSDGGDFDVYNCYSANWRDHLKFKLDVSSWPEIVNTALLTSSRFNEYWQVLLAKTGTVSTLRITRVKTIVEESNEVWIEFVLLYRHPEIGELDSELYSHLTPGFTAHTLIATAINNGEISFGGQKPGGGEFSLEAVRGSLALVVDADCTTTTAQPPTTHHTGPTNATTPYVPPGDNVIYTSGDLVAGVGVGLSVVGTGFRASRRTFLVVVKRLHVTLMNCCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHE0</accession>
    <name>A0A3R7MHE0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Uridine kinase</fullName>
            <ecNumber evidence="17">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_004802</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">May contribute to UTP accumulation needed for blast transformation and proliferation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 17">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="17">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Interacts with RNF19B.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="17"/>
    <dbReference type="EMBL" id="QCYY01001635">
        <property type="protein sequence ID" value="ROT76604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHE0"/>
    <dbReference type="STRING" id="6689.A0A3R7MHE0"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043771">
        <property type="term" value="F:cytidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000010">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000200">
        <property type="entry name" value="Uridine-cytidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 17 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="19">
        <location>
            <begin position="115"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="20">
        <location>
            <begin position="343"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00056790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00065923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT76604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="62136" checksum="945C9C977A3FD4CD" modified="2019-04-10" version="1">MSGRFKQDPPSSASSDSGGEDCIVPPMEEDESNAEMGENEGSQGPSSTRTISSTTPQTSNQNTLRSPRSRRQRTTSQSQTSRSGEPILRGRRRTIYTAGRPPWYDCQGQLVEPFVIGVCGGSASGKTTVAKKIIEELDVPWVTLLSLDSFYKVLTEKQHDDAARNEYNFDHPDAFDFELVVKTLSRLKEGKKVEVPIYNFVTHRRETKTKTMYGANVIIFEGILAFYSHDVIKLLDMKVFVDTDSDERLVRRLRRDIAERGRELDGVLKQYFKFVKPAFDYYIAPSMVHADIIVPRGGDNEVAINLIAQNVMTQLQQRGFKLREKLAHANFGIVRPSSLHLLPSTPQIRGLHTFIRNKDTPRDEFIFYSKRLIRLVIEHALALLPFTDVTVETPQGIPYEGKRIATEKICGVSILRAGETMENALCEVLKDVRIGKILIQTNLDTGEPELYYLRLPKDIKDYHIFLMDATVATGAAAIMAIRVLLDHEVPEDHISLCSLLMTEQGVHNIAYAFPKVRIVTTAVDPCVNEKFYIVPGIGNFGDRYFGTEPSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI72</accession>
    <name>A0A3R7MI72_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023534</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000705">
        <property type="protein sequence ID" value="ROT83277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI72"/>
    <dbReference type="STRING" id="6689.A0A3R7MI72"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="493"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="571" mass="64394" checksum="9C493D1C33EE2C9F" modified="2019-04-10" version="1">MVTLRLVSSAYRTANCLDRCEFEIRNTDALVVYAEDILSFQRFFDPGRLGAAAQEVTSLHVICSKALLGETVTAFQASWAPLTSRLLRLHLQQCRIMSFSPQAFQEFQCLTSLVVDNRNEGSPFVSSHGGLRGLPSLASFTLTRVRLRYIGRDLFQNASKHNLLKVYLNHNYLTKVDEYTFCGMRRLSDLDLSHNRLSNNRVDFLACIPSLYLFNISNNSIRELEKSAFSRNPMLHVLDLSHNNFTSVNTLIDLVNNTKSLKKLYLSGNPLVCNLTSLSRLHHLASQADIHVVDWEVMLCLQNEEWVSVQDLLFPYGFRRLFRVWHVAVVVTVFLVCFCCCLGLRYHADHPEVASQTALWQVIHRCFVGAATRRHSQAMQTKLPQTNTCISILHCTEGEHLAGPRYEEVIGELKHKRSITVKDVGTQSPFAIKRETESNDDIANAIRSEEAQEVCQSTYISYKTQLEPDSQQNAQRPESAVLKVLDGLEASEGDLRQEGGARSPAEQECQSEERSNEVDFEDDLPLSTSADGRITSHPSPMYATREHGPANDTRTPPRPSVTVLKLPSLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIQ1</accession>
    <name>A0A3R7MIQ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024092</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000780">
        <property type="protein sequence ID" value="ROT82741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIQ1"/>
    <dbReference type="STRING" id="6689.A0A3R7MIQ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT82741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="44065" checksum="5BE7626DB683A687" modified="2019-04-10" version="1">MAQATPFHPTLRRATCAGPEALTAQVDRQGSGNPWRQTRTWSGLAICQAAGLGDKRSFDLTFVFPLGRVSDLSPLFPLPLSLFFSLCSSPPLSSFSFSLFILLSPLFLSLALSRLFLASLTPHSPPLFPTSPISLSLPHFSPLPLFFPLPHLPSLSLFSPPSLLPSPLSLSSSLRSCLPRSFSHFLCSPFPSPTLYLHSLSFSLRSFSLPPTPLLLSSPLSLTPPLSPVLHSSSPLPSPSLLLPSPSLLPSLSHSFSPLSLSLLLPSLSHSFSPLLSLLLPLSSFSPLPHSSPLPHSFSTLPHASALPLSFSPLPSPSLLLPSPSLLLPSLSSPLGPCCSIIPRTANERNSVMTTRGKVHPPSRKTLNPINAYNNFESNAVAGSDAGPPSASGKYPFLCLINLVVNRDKATVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML01</accession>
    <name>A0A3R7ML01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001228">
        <property type="protein sequence ID" value="ROT79538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML01"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="49090" checksum="82C4B158A17E3F73" modified="2019-04-10" version="1">MSPIQPSQAYTPQSPGDTHTEDTHQVIQTSPETTHAKSPDDTPVGTRTAVSPRHTRTDTHQSPRQTPEITHTQVTRSRTETTHVRARVTRRATGDTHTSHQTHRDYAHWRESPKTRNTAEDTCTHPVNQKHTRYTTHTVTRDTHKTRDTRTDQSPDTAQTHTTHHQHNQNTHPSVVTRHTRWIYHHTSHQTQPENYLHSAVHQTHTETNTHCSQTRQTPEEHKHAVSTRCHRARDTLSRKRSRQSPSVTRLRKSNPDTPETHTGQSHRHTRRHATAEYTDTLDRHTRTQSPVPRWRQQHHQLTRHNRRHTPPVTRHTGSEDTHKCTKTHAKSTHGSHQTRTAVTRHTKTTAQASHQTHQRHTPVTRHERRGDTHPAINQRISADMTIHRHHAEKRHALAVSVQTHREHTPPQSPAHDQSPRHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MXE5</accession>
    <name>A0A3R7MXE5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Molting fluid carboxypeptidase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_009743</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the digestion of the blood meal.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002232">
        <property type="protein sequence ID" value="ROT71902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MXE5"/>
    <dbReference type="OrthoDB" id="6352895at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000040">
        <property type="entry name" value="zinc carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF140">
        <property type="entry name" value="FI02848P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 16" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M14" evidence="15">
        <location>
            <begin position="264"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="560"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="604"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="13">
        <location>
            <position position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00057299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT71902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="739" mass="81350" checksum="9BD48BB87D784CFA" modified="2019-04-10" version="1">MQEIDKASTFNITTRLLLPCPSGSQPSSSNKGEFVIEYTLELVKDSSKSASCLDLTIVLIHGSSVVAGCGPNVAASSLVGAWSVTGVLVPRSPAHLRAHGPSEESVFASLPRLQYVGRACAAFPTSRERAMANGRPNQLLFLSSLTFLLVNALPYEPNAKYNGWQVLQVRLEGGTPEALVQEFHDLEDPHELQVLRVSRVPDGSDSGLAEVAVSPTSKKDITDLLDARGVNYTTALSDLALKLAVDEPSLRQRDLLRGTATFERFMSFDEIQAHVEELPNLYPGQVTVRELSRTREDRPILLVTIHSGSDKKSPVIFVDGGMHAREWASPAAALFLVGRLLESPDLTGDVEWRIVPVLNPDGYVYSWTSDRMWRKNRGVTRSVQCTGVDINRNFDYHWGESGSSTRPCSSIYRGMSASSEPETNALMTAVLEERKRVKAYVSLHAYGQFVLYPWGFRRSTPKNSAELEEVGKGMAEAIRTVEGKDFAVGSSAKLLYPASGGSDDWALGVAKVPLSYTMELRDEGVAGFVLPPNQILPAANEAWAAMKSLGEYVAKRPTRGAANLRPANFGPPRPPRRAEPPRGGAPGGPRGAARLPRGLRQPRGQRERRERQQGRKLQRRGVLGRRNILVSECSGASPLTGVKCPVSFSRQRHEVARCIATRWWRVAEEATPFLALPRKRQLSQGPGHRNQQYGDKVTQTPLWRLTRCRPSSQQTTAFITVCPDRLHYFLVGLQMPAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MYE4</accession>
    <name>A0A3R7MYE4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002124">
        <property type="protein sequence ID" value="ROT72662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MYE4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="439" mass="47765" checksum="9AA530680B650319" modified="2019-04-10" version="1">MGSVPLCLPPSVGLVVVYRAEIRLPWCYGPNSRASHIWCDYYVASWNAILLYHPLLSLIYSNFSDCPSRLPCLLQLPCRPAKPFWRDIFTTSPVSLCQSLLREAYLSASPSSAPSDQLILSALTSVVTIPIYLSESTRGLSTCDVQTYSILLAISSKTHLLSFFDYSPFHSVPSPLLPFPSASLPCLATFYPLLPCPLPCCTSPSFLLSPPCPLPLLPLTLSSCTPSHFSHISPSNSPPYSPTRPLPPLSLSPYSHTYSPLIPILPPPCPPLPLFPSPAHFLSPSLSFSHSFPYPPLFLYSLLLYSPPPYSLLPSLSLSPPPPYPPPRPLSPISPPIPLLPLIPPPLPYLPSSPSLSLSPPPPILSPNQKDFISSHDAPHYAYSSPERQQSGFVLSGTGCQESAASRLSQVCIPDAQTPRRLVSGPLIKPRRILQCPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N9P4</accession>
    <name>A0A3R7N9P4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative EF-hand domain-containing protein D2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000241</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001036">
        <property type="protein sequence ID" value="ROT81013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N9P4"/>
    <dbReference type="STRING" id="6689.A0A3R7N9P4"/>
    <dbReference type="OrthoDB" id="6572480at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040365">
        <property type="entry name" value="EFHD1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13025">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13025:SF6">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="134" mass="15126" checksum="121C72CBA55C6DDA" modified="2019-04-10" version="1">MEQLPRADCFASFHPEYSEEELNKLYSLFCRYATPNTKKGHISLDSFKKLLEALQLTQTHLEAKETYDKAAKDGKLSLDEFMKLVKDLESKTGKINLDLVIKLAAQEEVDVDNVGVGGAKRFFEAKARILEQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NLS7</accession>
    <name>A0A3R7NLS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004084">
        <property type="protein sequence ID" value="ROT61606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NLS7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="46824" checksum="6A4E62AC8D5CE64C" modified="2019-04-10" version="1">MEFYLLTLSSSFFHLQPPSPCSSFFRLFHSFLTFLSLSSLSPNIFRLFIIMESTFSLLFLLPLLPPAPFIHSFDSLLTLSLFFFISLSPNPLAPPPSSHLQLPPFFILSSLSTFLHFLLLALSLLNIFRLFIHMGILPSHPPPPLPLPPTSHLPLYSFFRLSSHSFFFLLSLFPNVLHLESIHFSSSSSSSFFLPLPPCIIFDSLTLSSFLLSLFPNVYILLIHGILTSSSSLPPSSPPPFLHSFVSLITPFFSFFLLSLSPMFFPLFIHGILPSLPPPPLPPSSSHPSFSSFLSFSLSYLSSSFFLLSHLVSPRSSILFFLPPSSSSSSFFLPLPFPSFLPSLFLTTFSSFSYLSLLIFFLSPFKPLLSLLLVFLSSVRLSILSFLSLSISFPISFFILSFLYLSLPLLPLLPYLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NN54</accession>
    <name>A0A3R7NN54_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Beta-1-syntrophin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_019774</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the syntrophin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003703">
        <property type="protein sequence ID" value="ROT62382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NN54"/>
    <dbReference type="STRING" id="6689.A0A3R7NN54"/>
    <dbReference type="OrthoDB" id="409749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070161">
        <property type="term" value="C:anchoring junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016010">
        <property type="term" value="C:dystrophin-associated glycoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06801">
        <property type="entry name" value="PDZ_syntrophin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000052">
        <property type="entry name" value="Syntrophin beta 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015482">
        <property type="entry name" value="Syntrophin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10554:SF12">
        <property type="entry name" value="IP02644P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10554">
        <property type="entry name" value="SYNTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="10" id="KW-0965">Cell junction</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ" evidence="14">
        <location>
            <begin position="62"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT62382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="14955" checksum="16A2FAA79434BD46" modified="2019-04-10" version="1">MGEKVGNAEVLVGGTWHQARLTLEGDLLFVTLTDLDDLNLQGSDGEGGPSDVPEPIASQKRVVQICKSDNNGLGISIKGGRENKMPILISKIFKGMAADLTENLYVGDAILSVNGEDLKEATHDEAVRALKRAGKVVTLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7F7</accession>
    <name>A0A3R7P7F7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative G-protein coupled receptor Mth-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_019068</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 2 family. Mth subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003500">
        <property type="protein sequence ID" value="ROT63067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7F7"/>
    <dbReference type="OrthoDB" id="6134459at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15039">
        <property type="entry name" value="7tmB3_Methuselah-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.180.11">
        <property type="entry name" value="Methuselah ectodomain, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052808">
        <property type="entry name" value="GPCR_Mth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023311">
        <property type="entry name" value="Methusela_ecto_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="472"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="547"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="601"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="9">
        <location>
            <begin position="426"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="796"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="806"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="818"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="851" mass="95504" checksum="25FB6E5E80773A78" modified="2019-04-10" version="1" fragment="single">AADATEATSESGASTPRGPPSTTDSEPLTVVRKCCPDLHVWDLASSTCQISQDLQFIVPTFAMDIYGIYTEANLTRDQLQLRTGKVTCSSPWQLEETTNTFKVLETGQLWVVDFEAYYELDMYCLETFAENASAPASPHWLGAAVCHTQTPIEPFDASKITVRKCCLHNQVYTADSSCIPRANVTSEDWRVPLRPAGAAAGELAHVDVRQQPYADTHEVVASFQVCKRDEMGIEVHDFHVIEQTGKLYIPQLLREFSHDEYCIEDFFTDDVSIPTAYICVSEAERQQLHLSETPGCDSGSCVRKCCPFGKILDSMGRKCVDARDTYFNVTVKMEDGSQRLLSDIEFLTEYPDCKLQLTYEEEDVQLLQGMNLSYVSYSQEECDPRIENIIPQDNYCIDQVLYPSGMVKQGAAFCILEEPTAEKSDVRIIYSVFLGISDLFILISFIVYLTVPDQNKRGLNKNVKLAHSVLGRILLCFLFSMFFAYLFLIIINLFSDPIYLASKSACIGVGVCLYMFFMATFFWLNVLCFEIWWKCSRQESSSGRRWVWYQVYAWFGPITFGAISLIMDLTPSINSCYIKPNFGKYSCFFSDTLTHSNGAKWAYFFGPVAALLMADLIFFLLTVRSLLVTVQQSHKGTAQKQAKQRLKLCFKLFLVMGISWFAEIIAYQFGPSSFGYISNIFNCSQGFIVFLIFILKPKIMEAVRARLCGCCGDPKPAKLRGMLPFTSMVLTNSATTDEFSLSNQQLSLARSNVHNQISTISNSSNDMVVPPMSHHLPKHLPLSLCQPTELHAKIHNRPSSEFPSEGELRASSERSNSRDSSPSSSRPSTPRTTSTRGSLSASCKSMDEVTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9J6</accession>
    <name>A0A3R7P9J6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E3 ubiquitin-protein ligase PDZRN3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003225">
        <property type="protein sequence ID" value="ROT64588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9J6"/>
    <dbReference type="STRING" id="6689.A0A3R7P9J6"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051971">
        <property type="entry name" value="E3_ubiquitin-PDZ_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15545">
        <property type="entry name" value="PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15545:SF8">
        <property type="entry name" value="SLO-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="50886" checksum="31BA6C564A5E225B" modified="2019-04-10" version="1">MHALDAQMADIAHQCEQLEASHKTGPRSPEPPYKDALRRAESEHIYESIPDVSESDEPIYCRTSSSSGGQREDRRTVEKQQSVERWEERDSSSAYNTGDSTGSTHRPPPTLELSLGQDPALRQSTLTLCPPTHDQSLQVSLESDTYSAISCDSCRRCMRLPPLQHSLPQKTTNGRGLEPDHAHPNTPQHGHSSQKAESESNRNYVTFLPAQTMYTNAANLQQTIWLQQQLFRQALHRGSTAPSTPTASHRGGLPPRAPPRTPQDEPVKMEWKVKRRPDGTRYITQRPVRSKLLKERALKINEERAGLTTDDDAMSELKLGRYWSREERKRHLEKERERRRRHEMRRQQQQQQQLVHHPTPDDPPTALRTCTLENGVHQALWRDHSIRRKTSSTSDNAHKKLSSSSRRRVDVEEAAYGVRTPVHPANPPVPHHTAQQMMKGLLSVTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PC73</accession>
    <name>A0A3R7PC73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_025237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000950">
        <property type="protein sequence ID" value="ROT81610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PC73"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="533" mass="59163" checksum="545D6F57AE7CDCB9" modified="2019-04-10" version="1">MMSSEGEFEELEAQLPGEIPLTRSRLHTLITGGFRGRLRCHPQSRPLPQFSPSFHHLFPPQAHLLYLWLTHLRTLRHLLPHPLHLPLPHFASSFALFITLSFTVLEFSMSVPLIPSNSTHSFAPSPSPSLSPSLSFTSLSPPTSLSFLSTANHPLPHFLIFVSLLPILSPCPSFSISLSHLHFPPHLLSISLTLLHSFSSPPPPPSFSPSPPPPPSIISQRKAAHFPPEPATHIRGGKSVLLFIDVFRTRLVSARVSQTLTRCLSVWLALSSHLSGSVKDPSRSFISLSPLFTTASSIPPFFLNSILTLPSPFSFSLSRFSLSHYYPPLSSFPFPFIHLPLTPLPNPILPSSSVPFPIIVLPSPFSFFMIPFFPLPYPILPFSPLPNPILPPSPLLYPILALPFPSLFHHPFPPSPLFYPLLFPFPFLTRSSIYSPLFPTRSSLPSYPFPYPILALPSLFSLPPSLFPLAPILSSLSPLLPIPSSLFPLFPHRTPLPFSLFPHLFPSSSFIMTMVHYRSLSLLVRLGALDIWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEC5</accession>
    <name>A0A3R7PEC5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-binding serum glycoprotein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002712">
        <property type="protein sequence ID" value="ROT68158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEC5"/>
    <dbReference type="OrthoDB" id="6380971at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.30">
        <property type="entry name" value="Haemolymph juvenile hormone binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010562">
        <property type="entry name" value="Haemolymph_juvenile_hormone-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038606">
        <property type="entry name" value="To_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11008:SF9">
        <property type="entry name" value="PROTEIN TAKEOUT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06585">
        <property type="entry name" value="JHBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00700">
        <property type="entry name" value="JHBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="25689" checksum="E8A17E31DB482F47" modified="2019-04-10" version="1">MTEQSAAEEGGAVSAAGEEAIRSLLASCRESMKGEPGRTTAGVIPLDPLSVETQIITHQHPALTISVKLSNMALTGLSEFVIEEVKVNVQLLTITVSLAYDTLLLDGEYELQGKLVKVIPISARGPFTVTTNNAKVTLRAKLKECRGRLEVRDLTSDLILEGVRCRLAQMTGGALVSKVLNSLLTDLLRRERPRLAHELSAALKTLLNNELKNFNLGVSLQLLQTSDRLMRRGSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG59</accession>
    <name>A0A3R7PG59_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Nuclear receptor coactivator 6-interacting protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">PRIP-interacting protein with methyltransferase motif</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_003678</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="20">May form homooligomers. Interacts with CREBBP/CBP, EED/WAIT1, EP300/P300, NCOA6/PRIP, PPARBP/PBP and SMN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Cajal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000015">
        <property type="protein sequence ID" value="ROT86083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG59"/>
    <dbReference type="STRING" id="6689.A0A3R7PG59"/>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000066">
        <property type="entry name" value="Trimethylguanosine synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="457"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="270"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="23">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="510"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00057179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00064494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00079339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00081504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT86083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="939" mass="107090" checksum="F5C5B088B41034C9" modified="2019-04-10" version="1">MNVPTFIKTEWWGHGRAILRFSATEASRENAEATSQDKGGGIIECYVSSLIISEYTKKGPKKDAEQDEERPCGEAVEEVKTETYPPDVPIEIWQDWLIHWEAWKEVYISLSWVHKYKKLCKPDYIEWYDSYIENYPDVLPLIIEGLGEVTEDLEFLHNCPQEQEDSAMEIEAQTQEGNESKTDFSNSDKSNSNLKTNEGEEKKKLDALYDKHSEERYWIHLRRFLLLSGITKTDKLEEYFNRSANLKYSDTENYSTNMGALEEESCYNTSENSSALPTTDNNPKTVDTSPMYTNEGGFSSNKNTRKASRKSYDDSYECEEHVEKKFKSAGEEQQITNNEENENECILQTKVLEQERSDVTFDMDDVSQVKSIECKRGKKKKPKRAGLSNTSGLAWTLQILQEHSVGTNNADGNETHIENLKHPETQVDLPIDSSGTGLNDKFNKNIFPVISSSLDEKNPKAEVSPVNEEATSTKPNNCKDSTIDNTSSLGEYNSDIQTLQDSEQMVTSSEDNKNEMEKQKSEEFDGSKTPGLLKKIVGTFLMHGVKILYPVIADPLYGMIRLILPFQPSQPSVRDIAPDLNSQDLRKKWYPRRIFNMAQKKFSMWLKPVAFARMAGYGFKDLHLEEFEEYEELRESQAVYQKVEEKGPGDLHLLTLNLYDIAAESKNMTEEPSKRTHITFDEDGNPNIDETISTSVYMPADMEYNCTEEEIWDQLTQEHTRIMYKVVAISPSDVPEAVHKYWVQRYRLFLKYDKGIKLDTESWFSVTPETIAIHHAYRCRCDVVVDAFCGAGGNAIQLAATCNHVIAIDIDPEKIAMAYHNASVYGVEHRIEFIVGDFFKLAPFLKADVVYLSPPWGGTQYMQEKVYNVKALDGCINCETLISTAQKITKDIAIFLPKNSDLYQIIELAGLENCVDIEYSIMGNKVKALTAYFGDLVYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGE2</accession>
    <name>A0A3R7PGE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_010752</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002367">
        <property type="protein sequence ID" value="ROT70948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGE2"/>
    <dbReference type="STRING" id="6689.A0A3R7PGE2"/>
    <dbReference type="OrthoDB" id="10064773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005272">
        <property type="term" value="F:sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045902">
        <property type="entry name" value="SANBR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20946">
        <property type="entry name" value="SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20946:SF0">
        <property type="entry name" value="SANT AND BTB DOMAIN REGULATOR OF CLASS SWITCH RECOMBINATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="634"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="693"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="634"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="693"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="728"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT70948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="790" mass="88144" checksum="2C7710331D9B75B2" modified="2019-04-10" version="1">MYHHRCANSCVWSENTEGDADATRSSPRNTTTPKRPGGVDIRCSLFNTTQKVCMKKIAADDLDGVLECDCPLPCRETQYRSQVTSTRANMLHYELLHKLRKNVASFCSDKMDTVVLHVYLDSISYELIDESPTYTWDTLLCNLGGSLGLFVGVSMLSILEVLELLVDLCILTFSQKKRGRKDKKEWNQDEGELVKVQTQGEKNVNFAWVLEGSVGKCSAKCASQTELQVLREELQHLKMAFARRSAGLHPAVYGILAQLDNHPALTPSHPAPPAITRSRTPTPRQLESRRQISQHFRVAAAVVKRGQTEDHVPPTLEPKTAVSILISADFLKMAPLVEEVLQYVHDNINLILEAQVNLSCLSDAILTRLAYLFTHWELESLRDRRQNQNKLYAKFLQGLCEAYPSPARGIFKTASTLYRQGKNSRGKLFGDPGVSSITNYWRVHRVWKPRDSGRGAPGGLRARQYLHHTTTDKYTSYRAPLAALSSGSEMKFCRHQPPRRRFSDVDLLLASDTYPCCGARALKFSPLPVRNVRCLASDHTVQLSQGESDIWGPIPLIYDDLLTFQLLVCIDPPYQLTPESKNVLWTGVPLVPPNKAERSFLDRSWLAHFSHGERDSHAAVRPGLPENTAAAATTGVNLGVGTGVSSESSSDEEEGGGRPGLTPRLRANLMRRANRARRSVNCEVMAEPSLRWDSGRSTRHNQDAQREKETRLLRDLRRGSPWRPPTPTTRATAPTRDTAGVRTADASARTAPTPASTTGWNPSGTFRAKVQAISRIKMRLRHRAAFSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ38</accession>
    <name>A0A3R7PJ38_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_013761</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 21">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 21">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMTC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002717">
        <property type="protein sequence ID" value="ROT68132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ38"/>
    <dbReference type="STRING" id="6689.A0A3R7PJ38"/>
    <dbReference type="OrthoDB" id="10032188at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013618">
        <property type="entry name" value="TMTC_DUF1736"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052384">
        <property type="entry name" value="TMTC_O-mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08409">
        <property type="entry name" value="TMTC_DUF1736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 16" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 17 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1736" evidence="18">
        <location>
            <begin position="180"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="384"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT68132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="47009" checksum="24B6F5D0E6EAAE08" modified="2019-04-10" version="1">MGSFERLTHWLWNQNALLDHLVNVGLHMGVTVLYAHTLLTALRLSHAQALVSGLAFATHPVHTEAVTGIVGRADLLAALTFLSSFLSYHRSIQPETKNREGLWLWWAGIWACVGVLCKEHALMVLGVCIAWDLVCTSPSIKQRLWDRAGLNTVMPLSRRIARMLLLGLGVVFLRLLLMRTSPVFSDQDNPPSFARSRFTSHNTWLLLCPSSLSYDWQIGAVPLVSSVCDLRNLCSFLLYAGLVLVAKASFRLRQERGAEQSSVLAGVPSWASGGEVGILSAREDPAAAPFGTPPHLVPQDCQKELGLEVEGSAVRVSVGLGLAFPFPALVPPSFLPSLVAVISFPSSLVHPTLPVSPHSPLITLLITTYIFSLLSAVKLWWSYPSAHNNLGTILMQQGKYQEAEWHFSLALQSHPEHFPARGIWRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLC8</accession>
    <name>A0A3R7PLC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative transcription factor Sp5-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_011472</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Sp1 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002447">
        <property type="protein sequence ID" value="ROT70263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PLC8"/>
    <dbReference type="OrthoDB" id="6360012at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000014">
        <property type="entry name" value="Transcription factor Sp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000026">
        <property type="entry name" value="Transcription factor Sp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF170">
        <property type="entry name" value="FI01014P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="245"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="275"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="123"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT70263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="42910" checksum="0D4DD2B7D8FE8362" modified="2019-04-10" version="1">MQRPRARMTFGDLPVCPTNSHHIQGGKEGGEGRRRNGDLVICAVCHDLEPISCNKAKGKAGEIPHHFSLLIASTTISIISMYACGTLTESQLPHCLCPYHRRPTLAAHFAHVSTPVLPQHHYNAIAPPMLSPPPRNPSRPRRNRTHPPAGTLPPTTPPSHAASTYHFHPHQYASLALGGVAHVSPAVPQSVPSAVTHDAIPHQQSNIAALLTAHSSLTVRRCRRCRCPNCQDTSRDASAAKKREHVCHVPGCGKLYAKTSHLKAHLLSHSGERPFVCHWIFCNKAFTRSDELQRHLRTHTGEKRFQCEECGKRFMRSDHLNKHVKTHQNRRARLASASAEGDDVDVELCDDEEFLSVTLPDSPVSETDFQEPNDVIGNDQIQSISQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN17</accession>
    <name>A0A3R7PN17_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009934</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002256">
        <property type="protein sequence ID" value="ROT71748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PN17"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="461" mass="49038" checksum="FD2C9CEEA48D12C2" modified="2019-04-10" version="1">MCTFQSACACVPPVVFPPPCPPLISLLQLSPLSLALLSLPSILPAPLTPVLQLSSPSLLTSSPLSLSSSSSSLPSLLSPPSPLSLVLLHSPQSSPPPSLLSSPITPLTPPLSHLSLPRPPVSLPLHSSPPPLSPLPSSLALPSLPSSLPSLVLPHSSPLSPLPRPPLPSPHSSPPPPLTPLTPALQSLFVDLLLKRLFVPVLHLPSPLCCPPSHRSPFRLSFLGYIPFIPFLNLFFHSLLSSLFNLPFILFPISSFSFLPLLFHSLPISFLFLLSPPFSLSLHPLSPPSLLFHSLPILFLLFHSLPCPLSPPPLLFHSSPALSPAPLFHSLPILFLLPSPSFTLSSSSFSSLPHLSLSPSSPFSFLPLPFSLSPLSPLPRLSLFPHPLFPPPPLSSLSPHPLSSPSPSFHFSSSLLLPLFHSLPLPLSPSPSSGSPFLICSLARPSLLSIYRPLPGAFHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUN9</accession>
    <name>A0A3R7PUN9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000737">
        <property type="protein sequence ID" value="ROT83105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUN9"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="416" mass="46027" checksum="7E9F34BA0D8D9F91" modified="2019-04-10" version="1">MSGYPTRPPLHSRTAVQEHQRALYPIQPAEVPVIESAALLTRTTSFAGASLRRQEAVAGGTRSKTRSSMALTKSLLIRLSLAWHSPLNSLALYGHVLLVLLCAAFLAVMAGVGALDDEIRCVDQRTQEPVREQWLLALCTQYSGTEFQGRRRDALSYSLFHYLVMFMLALNLVPSAVRSHLDHRQMQKFLRTFGDNERQAAASTRDAAAQGRVSFVSLLVMAVNVVVLLTSSHMTLLDPSSYPFEQYLGETMSQFGHVFPGTAQCRVQPSMMLGAYTDTYGCHFPLSQHYRHILLAMLIVVGVGLVLSLLTFLIDAAMVFAGPSASLVYTACRDPGLERRVARQWTRDELEALRLVRQKTDMDAFVWILSQLDFEEDPVEVVVAGEASSASTEGDLERSVRLELDLSLGESSSDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVW3</accession>
    <name>A0A3R7PVW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001346">
        <property type="protein sequence ID" value="ROT78689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVW3"/>
    <dbReference type="STRING" id="6689.A0A3R7PVW3"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="2">
        <location>
            <begin position="85"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="20737" checksum="9BCD17A1E5EF7180" modified="2019-04-10" version="1">MQKFTYDTSVSAANFTLILQTESAMPEHQLPVTLEEIPEEEMARYPVRRTKGVKTFVRTKPGGVLMPATYAHLAKRFYNLELRSDDVVVAAYPKSGTVWTAEVVWALLNPHALDTLEAKPHHHRATLLDMELPKQSPRKLKDKQSSPAKRILSLPRRSLAGGVMSAPAGRSGSVPQDPEDTPSHQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVY2</accession>
    <name>A0A3R7PVY2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000566">
        <property type="protein sequence ID" value="ROT84293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVY2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="40868" checksum="8A37CB44859D850C" modified="2019-04-10" version="1">MRATWPSAEEPGLWKELGIYFSLNLALPFPPRQRSAASLPFPPRKRSAAAALACFPPLPSKKAVCLFPSPPKKSSAASLQKAGLLPSPSQESALPASLQERKKALCLLPSPSLQESALACSLQESGSTYFPPSKIAVRLLPFPSLQESGLPTSLPFPPRKRSACFPPRKRSAYFPPFQDSGLPASLPFPPRKRSACFPPLPSKKAVCLLPSKKAIAVCLLPFPFPSKKALCLLPSLPSKKAFFLLPSKIATALCLLPSPSLQESVLPASLPFPPRKRSAYFPPFQDSACFPSLQEKRSAYFPPSKRSACFPSLQESQRQRLPASLPFPPRQRSACFPSPSLQESLCLLPSPSLQESLLPASLVVADALFSSIKEHYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWG0</accession>
    <name>A0A3R7PWG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000485">
        <property type="protein sequence ID" value="ROT84865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWG0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="42062" checksum="F01343FFE6044862" modified="2019-04-10" version="1">MCPLSKISVPSLLFSPLPLPSVYLCVLVFRFCPSLRLPCPSLVFPLAFSFPLSIVWCPFPFLASHIRSSTFRSSPLYITLPFSLPSVLTLLVSSFPFLPPLAPLSSSSSPFLLYPLPISGVALSLFSSSLPLNSSFFLSFLFSLSKSSPTHPRFSKKSIRLTLFLPHYLVHPLVGLFRFSFASPFSFLSPSSPPASLFLSALSSPFPSLCLSFHSHFFRLPSLSFSLRSFLSPPSPFPSLSLLLLPLLPLRLRFFYPSLFPLLHLIPLSIHHFLLESLFPSLPPLLSSSFSLLPSLLRLSFPPSSSPSLFPSLTVLYPIFFLFSFPPMLSSFRYSLSVAFLRFVCVSLSVGSSVSLLLPLRQPSVIRPELCIPPPPVRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWW8</accession>
    <name>A0A3R7PWW8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposon Ty3-G Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_018263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000337">
        <property type="protein sequence ID" value="ROT85276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWW8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="45253" checksum="CB78B26478E4C748" modified="2019-04-10" version="1">MLPTRSYILVPAGRNPVSPEKSHRPPNEGRLCVGGNPEQLFPRVAAWLDNQDQNQDVEYENLKSYLLQEFTLSVSARAQKLLSLPHIPLGDTTAHAAWNEMQALATLPDLDPTTNKPRRVGLDAGAVAAAPSPSVRSALHEADDSPINDLIKKAAISSMLPEHLENLTQPTLHPPRTSLTSMLLTSDDPTHRFGAGAHKCLPGCQWPKTCNGATTPAKVATQNRDAGTSTHLTTQHRASLLRTPYLVANSSHSRKQNSFLDTTSNVKLVAANGSPIPMYGIQTIPIQAAGRSFTWDFIIADVKTPLLGADFLGHHGLLVDVANPSAKSTQTFFDQNSVSSLDSQPNMEYSITSKRQALRYTQNSGFYLQRSFKQLNKLTPKWNGWASVKKASSPWASPLHLVRKPEGTWRPCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZF6</accession>
    <name>A0A3R7PZF6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-1-syntrophin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003255">
        <property type="protein sequence ID" value="ROT64415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZF6"/>
    <dbReference type="STRING" id="6689.A0A3R7PZF6"/>
    <dbReference type="OrthoDB" id="409749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016010">
        <property type="term" value="C:dystrophin-associated glycoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041428">
        <property type="entry name" value="PHsplit_syntrophin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015482">
        <property type="entry name" value="Syntrophin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10554:SF12">
        <property type="entry name" value="IP02644P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10554">
        <property type="entry name" value="SYNTROPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18012">
        <property type="entry name" value="PH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Syntrophin split Pleckstrin homology (PH)" evidence="1">
        <location>
            <begin position="82"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="190" mass="21570" checksum="4C8783B18778C429" modified="2019-04-10" version="1">MVSPNASALESLAQWFPLVNPILVVPSFYITVKYLREVTPYFRKASVMADIGWELQSGFLGAENGFLNSDEDRSSPVMTNGPDTRSLPLLFCHLTRNYKCDEQYSLELHSPDRLHSLMIKCPSEADITGWYNALHSTLDRLMQSALQHANKMLGDVLDKATIHHIGWLKLKVDQGKEEWEPQFCLSQTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q232</accession>
    <name>A0A3R7Q232_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000610">
        <property type="protein sequence ID" value="ROT83994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q232"/>
    <dbReference type="OrthoDB" id="6376847at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="44773" checksum="CC78D3556525DC48" modified="2019-04-10" version="1">MTDAAPQQPSAEGRRFSYVMGGPDPFDQADKGWLGVAEVTEDKPPPKPIPQISTEEKWVNVSDVIRRQREEQARQEAKQKKLRPPPDPEESRPRAPSDDDGAARRGNRERKEEYSDRLRKREESDDYQEDAPGVDAITESMLQFALAPGLMVKDRGLARRSSLPATPTAYGRLDRSSFWTAAGRPPRRSSFTEEEDERPPPQHRPREQHVRRGRSPRRSFSEDKETERPHYREPSPDYDLEETSPRSAYRREYEPGRRGHRPHDPYYEDDRRHRYPDDDRGYDQDPRSYRREDPNDDWGYDHDPRSYRREDPNNDYPGGRHPAESRYDEDYYPRQPGYDRGAYDDSPERYYEGGRGRGYLRQHSDPRHGRGSQAYGHPQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q373</accession>
    <name>A0A3R7Q373_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014564</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002818">
        <property type="protein sequence ID" value="ROT67362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q373"/>
    <dbReference type="STRING" id="6689.A0A3R7Q373"/>
    <dbReference type="OrthoDB" id="6349011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03177">
        <property type="entry name" value="GST_C_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03045">
        <property type="entry name" value="GST_N_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000034">
        <property type="entry name" value="glutathione S-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000007">
        <property type="entry name" value="Glutathione S-transferase 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF9">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01153">
        <property type="entry name" value="Main.4:_Theta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="60"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="148"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="30994" checksum="54D8D9B335A23F35" modified="2019-04-10" version="1">METPPPPPHTHTSMPSHSRAAHVASFPDVSPELRARAADSRPSDAEQETPTARFQPSAIMVATLYYMKPSPFTRPVLLTMKALGITLELKEVNTFKGEQLKPEFVAINPQHTVPTLVDGDLTVCESKAICTYLIAKHGKDDDPLYPRDPKVRARVDSLLYFDMGTLWARFSGYFFPIRSGKATPETSQESLGKLHEALGWLDGFLTRGRFAAGTDHVTVADLVLVANVSGFEAGGILPDKYHNIRAWLDRCKKEMAGYEEANGEGVKFFGEFVKTTLKGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q871</accession>
    <name>A0A3R7Q871_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002348">
        <property type="protein sequence ID" value="ROT71057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q871"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="21403" checksum="9D848C1CDDFC8B25" modified="2019-04-10" version="1">MRTAEMLEISSLCEGRSASPAAGPSRPEAGAGRRARVSPSPTSRSWSGPRGRGGFLVADAVQVDSALGRRPVLAVLLGRAPRQPAGAHQGGAPRRHLDADGAAGRRDAKSRDAEPDGGADGGGRERRESSGSIGGFASIAGLQKEACPYCPHLTQKFEGVPMMRHLLVSHPCKPAFPCDSCWRVFVKRASFKSHQQKCQAQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAG8</accession>
    <name>A0A3R7QAG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002102">
        <property type="protein sequence ID" value="ROT72845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAG8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="55721" checksum="3B77B46E47565725" modified="2019-04-10" version="1">MPPKVPPPQRRASVEPETKDKASILIFHVISVRRLPSSPLPTPPSLPIPPHPFPLLLLPTPLLPLPLPPSLPPFPLTYPLPTPSPPHPSPPTPIPPPSLLLPPPPPSSLSRRLNTDISPSSQKIKTRSGRGDCDTAAASSVVGGMRVVVRKPLDLVPLLHFLLSLLFPFLSLSYSLSCLSYSLSSSLFLSSLSYSLSFLFYSLSSLSYSPPLSLSYHFPLSLLFPFLSLLFLSSLSLFPFLSLLFPFLSLLFPFSLSYSHSSLSYSLSSLFYSLSSPPSLLSLTLSSLSSRLSSLSPHSSMFVPLSFFFPVYPFLLRLSTLPLPFSSLSFLLLPSLSLPSPPLSVLSSLSISSFSLSPPSVQSTFLLLPSPLSSPSSSLSPPSSSLISLPSFLFPRTSPFAPFPSKSHRKTKNNFILPPNFLLTSKLSPSFTCLSSNVRHLRAHCKPSSDPPFLRPPPPPGTQPPPVTTWGNHLPPPRTHLSSPDLQRHQEFGGAGVRATEPRCDYKRGRRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAY1</accession>
    <name>A0A3R7QAY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Prophenoloxidase activating enzyme III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020031</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003812">
        <property type="protein sequence ID" value="ROT62135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAY1"/>
    <dbReference type="STRING" id="6689.A0A3R7QAY1"/>
    <dbReference type="OrthoDB" id="6368658at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000028">
        <property type="entry name" value="Serine protease easter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="71"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="331" mass="35988" checksum="7647AC6EB7983F7B" modified="2019-04-10" version="1">MRVRVVLAVKMVMMQSIQRVHVTVSAICSVTEGRALVCCEDTQPVISPGPSLRGRDLLPRECGQTALVDRIIGEPAPLLSWPWMILLRGRNAEGRRRFFCGGVLISERYVLTAAHCVHSGATLSLESVRVGEHTVGQDPDCQKNRCAPSPQDIAVEQVVVHEDYGTPCLNCNDIALLRLATPARIDNLYVTPVCLPVDPLRDLGFSARDLKTKRAWVAGWGATEALASRTGTGTFSNVLQHGNLPISDRFCQFDLQNYPDPDMVLCAGGEDHDACNGDSGGPMVISNNGRTRRFVIGVVSLGPAVCGAPESSGIYTSVIYYMDWILNNLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBQ4</accession>
    <name>A0A3R7QBQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001975">
        <property type="protein sequence ID" value="ROT73888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBQ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="17930" checksum="3E34EDFD60D803F5" modified="2019-04-10" version="1">MTDLRSVHSSRERRQIRNLAEAFVKVSVLGASQEAFEGAACWQRWVLVWQSASGCGSGKGPRHSLPECCAKSFALKALRCLVENDCLIIARRNRQGERQRTDVSRSQRKAKGGERRAGKIVSCLHRRQRKLRQSIVCRPSIFSLSPFLHVLPRSLIPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE85</accession>
    <name>A0A3R7QE85_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003219">
        <property type="protein sequence ID" value="ROT64638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QE85"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10529">
        <property type="entry name" value="SET_SETD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46462:SF3">
        <property type="entry name" value="UPSET, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="3">
        <location>
            <begin position="211"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="491"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="739"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="792"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="947"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1021"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1088"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="745"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="859"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="947"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1140"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1215"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1235"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1305"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1327"/>
            <end position="1355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1510" mass="165341" checksum="9D969E1F89A2205B" modified="2019-04-10" version="1">MSTHVDCMEIDRENIPDEYLCEACEPRMIDRFKARALQIRRRQEIKAHLARLSSSDSDDNMPMCNKSRASLSKVQERKVVKKKKVKQIKDMKNGRKGPLSLLKKSSSVSCNNNIVPGSEERDRRMLVKTRRRKSSSMSGGEGVSDDSCGGPVERLRAWVEGYEVAVTNHYSPELRARVQAARINGVSPDLRASTQGAVLGHRCKVMENPNPLLDVFDSKILVAATRLTVNTAITEFQGKYLLASQWNAQQPVMGQQYLPYVLQYHMPKEGLTVCVDARTYGNDARFTRRSCRPNAEIRHVVERGSLHLYLVATRDIEEAEEVTLALETANSTLDLVCCLSEEHDCNAPQSQKVEALSPVHNPPHKKNGLLNNKKTIKKQQLQLQLRTSKRTTSTESRSSDNLTTTTCQSTTPVTPVKQRRVSGCGKSPAKSPCVSASSSPEELSKDTVVSAPPTLAVTPETPKAMDKQQQQKMTREERKIAAYMKAFERMEKAAQRRQEMEKKKEEDKSKDPKDKDKKHCDGDEEDWEKTSSADEGNRNTPVAERSRRKGKKGRGKGSPQKRNHRLDTTASDLTGDESSCASVGLMSPLGGSVEGIALNFNSPPSGNSNVMGFRFPKTKKALMNEWLNETVDPVMPVGSPSGVTEVHSTGVPTCYMRSPATPLRRSTSVNQVVPGTVLNLDLPGGSAKKRWLRQAISEETESPQLNGLCPSPNSRPGGCMIVHPNRLPNWRDLQTPLKKRRLARESMSSEQSSTPPSTPVHSTSMEEDKMMEEMEAELAAGGVVKIKCEEESVAEDQSLQGEDHTGDAADTKDSLAIKEESTQETTVGKRESDMGCGSISVENVDERTPKEEGETDGSTGEKVEENKEKEGVDVKSEIGETDGNPEKAFRDAPKAEVGSVKPETQGRMIKSESGGDAAECGSSFQKTVKNELESLIATDCRIIVKKEKEVSEVSDDREKEGSDERTENVGNIEEKTPTQCSRPERKQSSKKPVSVKMEVLNDEQVKQEAVQEKPEICAGEVVGIREQSGSSSEREEQEKELVRANVHHCMVVKEGSTKTNAKAEQVLSRETCIKQEVKVEVDVQFNTSVKIEERDNIPQTQSQGSEETEVTECISKPAKETSPAPEEVLQREKSLGLVCSPSSSVLQGRRQSSQSDSDDLPVIERAQTPEGFHHKALEPKGPRTPEGPAPTSPEESSLMPDSPRTPESCSIGQDRSPEREASPERTSRARVRGPCTPPSTPPPQQDDSLDGESEREREQQDDCDKSIKSALHAKAAPVKRKLSILEYRKRKSVSSESETRGANGPHTSGSCAPSPVTLPSASITQEPLSSPSAASPAKTSCASAVDSSPDLSLSPIRPLSLSLPAVLDDKLTKDEGKREVESTTQRGDAAAEVSKDIIGSSKNNTGIVATSLPGITTSTVTAPTGTASQDVKWNAAPTLLERQRENLTARLRREFGLCISDDDEDKSGLRLGCVSVVGRPSPPLLPSPFDLLITPFATGQKAFRAPGWDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QIV8</accession>
    <name>A0A3R7QIV8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Mediator of RNA polymerase II transcription subunit 20</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Mediator complex subunit 20</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED20</name>
        <name evidence="7" type="ORF">C7M84_000963</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001132">
        <property type="protein sequence ID" value="ROT80315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QIV8"/>
    <dbReference type="STRING" id="6689.A0A3R7QIV8"/>
    <dbReference type="OrthoDB" id="1854899at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013921">
        <property type="entry name" value="Mediator_Med20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12465:SF0">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12465">
        <property type="entry name" value="UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08612">
        <property type="entry name" value="Med20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT80315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="135" mass="15337" checksum="22D98FC40E4249D8" modified="2019-04-10" version="1" fragment="single">VTLSADLLFDFILPRFDHMYQSKKNLKIESKGSRYEIGDFVVKIGTVTMSGHYKGILVEVEYLPCAVPALCWTLMREFMQSFMGSCVNPQAPPYIQNRFHDIHAAQDTVQQYVEKFNEFRDGSTYSGAQANAPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QME1</accession>
    <name>A0A3R7QME1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002202">
        <property type="protein sequence ID" value="ROT72125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QME1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="490" mass="56394" checksum="3B7A9C77EAC7CDD8" modified="2019-04-10" version="1">MYHEFSLAILNFLEFPLPHFNVSGGGGGTHLCPRLLPPSPPYFQYLFFFPSTVSSFSFFPFQPFSVSLFFPSTLSYLFFFSFPPLFVSLFFPFHPSYLSFFPLPFRLSSFFSPSTLFVLFSFPSTFRISFFSLPPLLVSLFSPSTLSYLFFPFPPFRVSLFFPSDPSGISFFPFNPFSSHSSFSLFPPCISLYISLSYSFSLATFSRIFVSFLSLPPPFRISFFPSRYPFVSLSFPSTLSYPLFFSFHPFVSLFPPPPNPFRISPSPFPLFSPPLFSVLPSLLLHLSLLFFLLSFSLFFSSFFFSLTPFFVVNALSLSLFPPSTLLRILFFFPSTFRISLFSFFSSSTLFSVIIFFFPFHLSFRLILLFLLPLLPQSFPLPPFSLPSLSVPNLSVHLFLLSRFLTSFSLLPLFFFFSSPLLPPFFVSSSFFFPFPLFFVSFVLFPLPPFRISFFPFTSPFLVSLFSSFPSLSHPFRFIFFLFPSTLFVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMT0</accession>
    <name>A0A3R7QMT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative zinc finger SWIM domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009106</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002141">
        <property type="protein sequence ID" value="ROT72518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMT0"/>
    <dbReference type="OrthoDB" id="10013584at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031462">
        <property type="term" value="C:Cul2-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048370">
        <property type="entry name" value="ZSWIM4-8_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22619">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22619:SF1">
        <property type="entry name" value="ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21055">
        <property type="entry name" value="ZSWIM4-8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZSWIM4-8 C-terminal" evidence="5">
        <location>
            <begin position="447"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="184"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="511" mass="54437" checksum="C09BBAA8E8B5D18A" modified="2019-04-10" version="1">MFELAKTVLNRAGGNISTSLFTQPSSSQNHRGPHRPLHMCAFQIGLYALGLHNCVSPNWLSRTYSSHVSWITSQAVEIGSPAVSFLIDTWEGHLTPQEAASIADRASRGRDAATKFLSAFMPHALNPNEIQRAIIQCKEQSDEMLESACFAVEGAAKGGGVYPEVLFSVARRWYELYEARTRHQARHQARTSGGQHAGDQQQQPPIPPMDAQSQPGLHPPVSVGMNGNGGAGALPGVAGYPVAAPPSSVPYALTGIPYQLGYNYIQGLPTSVSCINPQMPMPMYIQPPGVPFSGAQGVSQPLMPPPSMQYFPPVSIPSTLPQGTLPGAGGMGGGLPGGQQNLGPQPPPLGAGPPPLPQQPPLIQGNTPPQQGFYPLPYSNAVGNGGVSTAGFIGAQPTALLSWVRAQGPHMVQPSPHQPQLPPPPTSQPQQQVPGLVGGQQVNNNGSMNYLLSTYRVGMLALETLGRRVHDDRPQAKYARNPPYGEDVKWLLGVAKKLGQQYLHQFCMFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPP9</accession>
    <name>A0A3R7QPP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007466</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001948">
        <property type="protein sequence ID" value="ROT74047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPP9"/>
    <dbReference type="OrthoDB" id="8998425at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.230.10">
        <property type="entry name" value="Lipovitellin, beta-sheet shell regions, chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015816">
        <property type="entry name" value="Vitellinogen_b-sht_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="184" mass="19582" checksum="10812A26729FEA51" modified="2019-04-10" version="1" fragment="single">MPKGTALSSAQAACTESEFTCVSDQECISLDWVCDDFPDCNDRSDEEPEIDCSTFDPGAASSSAGSSSSSSSSGGSSFNTNTDDDDDASSPVEETPDAPEASSGLSQEDTSEEEEEPEILPEKCSLSKCRSRGKMKFLDGRTYHYKYQTQTTTQVVGSSPKNTTISMEAALALNVLTACEMELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRH4</accession>
    <name>A0A3R7QRH4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001760">
        <property type="protein sequence ID" value="ROT75522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRH4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="668" mass="71324" checksum="53010F81779E5D47" modified="2019-04-10" version="1" fragment="single">AISPLPPLLSFLPTSLSFLFFPSPVFLPTHLSFPSSPSFLSRLPSPLTSLHSSPLLAFPLSLSTPLPAFPTHSLLSTLFPPLSPLFSLLSPLLSFTFSSFTFLYPFPFSPTSLPAFSLPLPFFPPSPRPLTPLSLPPPSFPLASFSTLPTSYLSLSPPYFPTHPSPCFSFPSLSSAPPQFSSHSPLFLPLPIPSPLSFPLFPSPSLFTPSPHFSNTRLSSSPPLPTPLPTFPSHPFPALFTFLSPLSSLSPLFFTPFLSPLPSHSSSPFPLRFTSPPLSLPPLPFSTHLISHFSSPLPTFPYPTSFTPYPSPHFFLPYFLSPFFNFFPLFPSPAFLLTLSLFPTHSSPLSLLPSLASPISLSSPPFSHPSFFPLLSLPHSPPPLSPIPTHLSPHFSSPFSPLPPSFPLSPLSSSPLFLFPPLFPLSLLPTHPHPTFSSPFFRLSPLPTPSPSLSPHSPHFSSSSSLPFPTSLSPLPSPTHPSSHFSSPFSPLSPLPSPSLLISSHAPHSSSPFSLSPLSHPCLPLYLSHLSLSPLTPLFLSLLSSLPSPTHLPSPPLFLLPSPFLPLSTSPFSLPFSFLPLSLPFSLSPLSPPLSSLLSLSHPSLPSPSPLPPLSALPFPPLGSLAGAEHVADGSCAAICGSRSAPAATRHPGPGRDLFLLPVLSPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRK4</accession>
    <name>A0A3R7QRK4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001752">
        <property type="protein sequence ID" value="ROT75610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRK4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="442" mass="47005" checksum="B0CF8B7C23B5F4F3" modified="2019-04-10" version="1">MIINIDDTNATEAEKKSAGKRRGKNKQKRNAVRTALTPPPQHFLHLLNPLLDHRRLSSLFLPSPPSPNSAGTLQNVFPGIASLKRTHSPSPVSWSPFSLPSPVLPSFILPSGSPLLKLPSSLLLSLLLPVFSPISLVNLLSPPPPPLPISLSQPPSSPLPSPSLPSCFSLPNSLRLPFYRLRSPPLFQFSLSPSPLPLYPPPRPQTPDPPSPTQPHPHPAPTPSIPHPDSRPPSPLPSIPHPDPSPHLDPSPIPHPLLPHLDPSPPSSSPIPSPPSPTQTPDPSPSIPHQTPRPLPPPPPTQTPPPPPPQLHPHPSPPDPSPPSPTQTLPSIPPRPSPIPTQTPDPTQNPIPPLHPPPRPQTPPLHLPTPPPPSIPRPSPSPLPPSPRPQPRPSPPSPPRPLPSIPHPPDPPPPPIPPPDPSPLPRHSQLARAPSLPTSPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QTB1</accession>
    <name>A0A3R7QTB1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">thiopurine S-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_003980</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.</text>
            <dbReference type="EC" id="2.1.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.67" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QTB1"/>
    <dbReference type="STRING" id="6689.A0A3R7QTB1"/>
    <dbReference type="OrthoDB" id="276151at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008119">
        <property type="term" value="F:thiopurine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000101">
        <property type="entry name" value="Thiopurine S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025835">
        <property type="entry name" value="Thiopurine_S-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10259">
        <property type="entry name" value="THIOPURINE S-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10259:SF11">
        <property type="entry name" value="THIOPURINE S-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023956">
        <property type="entry name" value="Thiopurine_S-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT77365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="25923" checksum="B2598EAC0D8CD780" modified="2019-04-10" version="1">MSSDERVKYWDSAWSEGRSHWHANDINFALEGYGRLLLPGPHRRVLVPLCGKTVDMKWFYDNGHSVVGIEGVEMPVKDFYEENGIPYTTEELSWGKLYSSSDRRLQLYCCDLFEAKPEELGKFDAVWDRGSLVAIYEEDREKYSQFIKSVLAPDFRYLVNLVQYKANELFSGPPRNIPNELVLQLFGDVCEMNVLETVKWDKEDGPMYEYGRQEVVVLLTPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QZE8</accession>
    <name>A0A3R7QZE8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000516">
        <property type="protein sequence ID" value="ROT84659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QZE8"/>
    <dbReference type="OrthoDB" id="6365772at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="435" mass="47957" checksum="936EE0C43E8F3453" modified="2019-04-10" version="1">MSAYSRRHGRDCGDEQVGLPGSSAAAIMRSAAGGVGGGRRRSQGLGASAAGRTPSSGLLFLESLPTGAFSTRVLFSVALTSSLLRDYDNSSSRSVLARLRKMEAMKVLTSLLVLTLTGPTLGYPYTRGMPSRTSGRGREQMLEGGLGEYLGGYMQDQQYALPEYQPTYRHGYAAQRPRINAEALAALLPYLTGANDDYAYDYNTYSDDEGTWYDDTANADIAEPVESDDAALFQYLINHRNGRYSLEDLENLEREAEMEDNTENQLHALLAKKISKKANMPVLGSRQVGAAPLPAVSLRGQKEEALDIPATSIRRPVFARQITTQPEEQTASESAQVSNDKRSVVSTAKPEEEKTVSSTPVSAVTDKADESTTMSPYMLNRYDAFLKYLDRERKVRQQQDFEQELQQEMRPPQKRFITDQEALTQQLASLKKSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QZI5</accession>
    <name>A0A3R7QZI5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor TFIID subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000495">
        <property type="protein sequence ID" value="ROT84808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QZI5"/>
    <dbReference type="STRING" id="6689.A0A3R7QZI5"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22932">
        <property type="entry name" value="HFD_TAF6L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000030">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.770:FF:000001">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="8">
        <location>
            <begin position="9"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="362" mass="40671" checksum="8BD904C9CCAAF824" modified="2019-04-10" version="1">MAEDCQVAPSFPTESIKVIAESIGISAVGDDVAKELSEEVTFRLKILIQDGMKNMHHGKRKRFSTADFDNVLKLKNIEPLYGIHPGEHIPFRFASGGGRELHFLEDKELEINEMVSSSTPRLPLQMTVKPHWLAIEGVQPTIPENPPPITKDAQKKDSVDPAAKLSAQQENKDQKHIHGRGMKSIETVKVKQLATHELSAEQQLYYKEITEACVGSDEPKRGEALHSLAFDPGLHQMVPRLCTFIAEGIRVNVVQKNLALLIYLMRMAKALLDNQTLYLEKYMHELVPSVMTCIVSRQLCMKPDMDNHWALRDFAARLISQICKNYNTTTNGLQTRITRVFSRCLNTERTPLSSVYGAVAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SHW3</accession>
    <name>A0A3R7SHW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003942">
        <property type="protein sequence ID" value="ROT61900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SHW3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="659" mass="73221" checksum="566C144F97CAC8D3" modified="2019-04-10" version="1">MIANQLGSDGVHTVERSLNQFLFFSWRSQAHLGGGGDVGGALSLIPPSSHFLCLSLPPSSPYSISSPPFLPSLIPFSDFLSPSILSLLSDSFLISLYESFSPSLLILLSTSHPPYLNQLSDSLSPSILILLFISLPSFLMYPFFSLSPSIPILLFISLPSFLMYPFLFFFSLSPSIPILLFISLPSFLMSPFFFSLSLLPSPSYSSYLSPPSLCIHFFSFFSLCLSPSIPILLFISLPSFLMYPFLFSLSLLPSPSYSSYLSPPSLSERRLMRTARARRVNTGECPHVAGSGRRGSLGRLWGTGWHSLVPFSKMLLLLFRSLFLLSISIPFPSFLSSFTFNPPVSLSLLFLLIFLSFYSPLHPFPFLLFSSISLPPFTISYYYYLPFVLLSFSFRLLAVPSHPPPSIPPKQLCSTLLPHLTPSLHIFYYYLPFVSFRSHCCSLSPQPPYPLDSCVLLSPHLTPSLHIFLLLPPIRSPFVLAAVPSHPPSIPARQLFLLSSPSHSFPSYLFIITSLSFSFRSHCCCLSPPPSIPSRQQCSTLLPHLTPSLHIVLLLPPIRSPFVLAAVPSHPPLHTLKTAVFYSPPPSHSFPSYLFIITSLSFSFRSHCCCLSPPPPYPQDSREARAGGARRRVLSVSRSRRRRRRDWRRVSGPGGASPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBL6</accession>
    <name>A0A423SBL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative glycine receptor subunit alpha-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020608</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004090">
        <property type="protein sequence ID" value="ROT61595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBL6"/>
    <dbReference type="OrthoDB" id="6351594at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019216975" evidence="6">
        <location>
            <begin position="31"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="739"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="845"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="891" mass="100464" checksum="E59AD4D9CA60D7BA" modified="2019-05-08" version="1">MHDRGKYIPTLRIMFLAIAVLSFQAEVALADIPAYGFYASIPPLANWTWLQKEIVFPPSTSEATLCINVELHKSHPNNAAILTLNQSFVAGVENDKYKIYNLGFPMVFPRTVSPWQWVLLCYFVGRTTGMAIDGEPLRIEEAEEKLRQMDLTIPYNLTVGIPSTYYDDLSIVQSIGGRVTIPRIFLRRLDKQEMLTLAGCGEVPGEDLGNGVWQVIGGGNVKIGTITSTSNFSEYLVSDTNAANGENKYIMMGYAYLNYYEARDYCIAYGGNLPNVSESSTWDFFVKVSMQNYTSLLSVWANDCFRFMAYEGNYDIMPYRCLDDLKALACEVPKTQRFEIRADNDAEEEAFYLLPYSFKPAFLALSGRQIQTDGNLLTLLDSDGQKVASAVNNGLQPVGRFEWKYENEEKRVFTFTACSKDEFTCSNGLCIDLNKRCNGIEECSDGSDEECSILLPLPATYRKERPHKFFTDLNLTVAAMDVLEVDVYENVIRVNTEFRTSWRDGRIHLSQISATASENVIDAADIWVPSMELNNAVFKDILSHLRRSEVRDVVLAHRETSGTILTQEGLEGYTYNANQDAFLELVEIFEASYKCHFELGLFPFDVHVCSVNISLRQFSRSFKAVFRDIDVSTAPKSKKLPLITPSKFCYIPHADDNGDITKVTFQVLLRRRYASYVFTTFSPCLVLTLIGYMTQFFSHENFSDRIMVTLSCLIVVAALFSQIAATVPASASHKAIDVIFLIIIVRLFLVVLHHSVLFLIRRSVMKAKEEALESGMEGGGAVPGPALYQAPKKFLLPPWTGQGPVTPAMVHKGHNPPSAWAELDPMAKKGKQQESNKEVRAYDEIFNIFSISFGMLVDVLWISLYYYSISSERDLVMQEFEKCLETMRAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCI3</accession>
    <name>A0A423SCI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hrp65 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003964">
        <property type="protein sequence ID" value="ROT61875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCI3"/>
    <dbReference type="STRING" id="6689.A0A423SCI3"/>
    <dbReference type="OrthoDB" id="10067824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12945">
        <property type="entry name" value="NOPS_NONA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000043">
        <property type="entry name" value="paraspeckle component 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012975">
        <property type="entry name" value="NOPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08075">
        <property type="entry name" value="NOPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="36"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="110"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="238"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="36532" checksum="C8EC27AABCDBCCDE" modified="2019-05-08" version="1">MASPEDRVLERLKALSGPMIDLVPREENVRKFSNHCRLWVGNLPLDIKEDDVKELFKPFGEFDEVYFDKNKGFAFVRMDYKSNAEKARQELHLKDYKGRQLKIRFSSPGTALKVRNLSTWVTNELLEKAFSVFGELEKAVVITDERGRATGEGVVEFCKKPAANLALKKCQDGCFFMVASPRPVIVEPMAVVDDNEGMSEINVNKRNPEYIKERQQGPRFAQPGSFEYEYGLKWKQLYELFDKKKDSLERELNDEKRKLEEQIEYAKYEHDTEMLRERQLRMSGQALMLPLYPPPPRSGILETRKSVEPGGGKILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDB0</accession>
    <name>A0A423SDB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative endocuticle structural glycoprotein SgAbd-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019954</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003764">
        <property type="protein sequence ID" value="ROT62207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDB0"/>
    <dbReference type="OrthoDB" id="6372059at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="256"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="273"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="481" mass="55071" checksum="C39FFF0D33B1E10A" modified="2019-05-08" version="1">MQIFWLLLASSACAQQTVRERQQSNLQDQQFSQPAVTPSRLSQQPFLGQDSLVQPLPVVQQSFGQQTPGVLQAQQPARQNQLGRLRLEELRRQQEIQRRQAAQRQLEVRRRQLELRRQEENRRREAARLQLERERQRQEATIRGQERQREQEELRQRQQNLRQQEVERRRLQANIPTLDDVRDGPFQDGTYYFGFATGNGIVREEGARLTGPYTHEVTGSYSYTAPNGEVITMEYIADENGYRAYRARPGRINPVIPPNRIFETPPYRPPTNSPLQNRPFTSIANRPRPNTAFRPATTQNTNLPIIGNNQQNFNTQNTPRPQVFSAPITPRPQVFSAPNTPRPQVFSAQNTPRPQVFSALNTPRPQVFSAQNTPRPQTFSSQIIPRPQSFNTVQPQTFSNNANANFNNQDIQLPQTFSTNQPANTFSDQNVQTFGTNTFSRRVGLDEILTVPEEEYDYGGTLTQAVLGARPPSTFDSVLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SF89</accession>
    <name>A0A423SF89_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003531">
        <property type="protein sequence ID" value="ROT62877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SF89"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058831">
        <property type="entry name" value="LolA-like_dom_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902:SF1">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25898">
        <property type="entry name" value="LolA_2nd_metazoa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00473">
        <property type="entry name" value="PAN_AP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="918"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="3">
        <location>
            <begin position="787"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="963" mass="108292" checksum="D0538EB52808072F" modified="2019-05-08" version="1">MHSSPIHPSTAHPPAHPSIDPSHPSTHPSHPSSKHPSAHPIPSTIHHPPTIHPTIRHPSIPPTHPSSIHPSIHPIHPSPHPSIHPPTTHPSHLHQPILPPSLLPPHPPIHLIPSPPPEVPWQMPEITWFPGEDDRIPVEFEVEMQDMSELYQYHVLKFVPWVEHHHLLEVPRGLSCEGLVGVVSDLPVPDIPSHFSLAEEVVSNPMIDGVSLGSQHLDKVKFAYAEDLSLVRLDVVPPNYITALTDHVVEIVHDFNTGAQYIIDREFGNCSIDRIPDFTFDTHFGGMLGTGGSMLGPNELFHLDDTYAYVGERSTREVGSDMWTSTRDDIPDPEVGWEENYPKAVLEYYFSQGVEVTPTNKVPVKMPIRGDLFTYNRSNPLQVTGMMTTNFYDFKEVALYTETEFSVEECYERWSDRWSYLIITFPAAHKNQFQAAEKKPDLFKHKVLELIISRGDISPVRIASIDVSEGVSGLIPNTTDADLIIVSVKLLERAPYLLSFRTPSDEPNKFPGVNEKSFEGVHTEDCARFCLEERGFQCKSFHHCDDRICFLSSLDTADGEPVDTVNKCYHWISSVDNQTFVDLPSSEVYSVILDAIRHGKFMFSIPYKNDTVLYEASMSFHYRTPDPLDPIRMQFTLEARSMTIVKVDYIQEDMAILDECLALCVGWKAFRCETVVHKPIDKQCMLLAAHYHDINSTYIKPESDSWIHSRSYLADYSPVFGGVALNTSGPTYENVDHLEACARYCSQETSISCQSFEWCHELRLCHLHQEHFLDVVDGGNYEVHTSCIHFSKRNDQLFSRYPHQGLPSDSNRLVAFKTDVSSCAKLCIEESDMTCQSFDFCTECGDDEYSVCGEDNSGSTNLCFLSSHHLGEDGVALTAATSCEHYSRDVFGDVDYPTWVSRQRKSDKPYTSGDMTGLAFGMIFLGILVAVAFLFGMTYAKPTSVPKDFSISFVNLKSGESSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI39</accession>
    <name>A0A423SI39_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_018270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003371">
        <property type="protein sequence ID" value="ROT63824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI39"/>
    <dbReference type="STRING" id="6689.A0A423SI39"/>
    <dbReference type="OrthoDB" id="6381385at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT63824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12099" checksum="DC663E267182444B" modified="2019-05-08" version="1">MAEQDFVSNNMMGNGWIGLNDRGTEDDWVWSDNTKVSITNWNDGEPNGNAGNENCGEMRADTGKWNDLPCHLARVFACKSKASATPVSPVQPTTTPYPDCEWGMGGERED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ01</accession>
    <name>A0A423SJ01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase-activating Rap/Ran-GAP domain-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017879</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003302">
        <property type="protein sequence ID" value="ROT64196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ01"/>
    <dbReference type="STRING" id="6689.A0A423SJ01"/>
    <dbReference type="OrthoDB" id="2499658at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF27">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00780">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="CNH" evidence="5">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="456" mass="50933" checksum="C61EF83DD3C07EDE" modified="2019-05-08" version="1">MRRDSKIHVFRLSDFECEDERVKTKADLKDHRLERTKGCHLYAISRPGGSHLRMVGLGRTSWGLWVVAVNKKLLVLQWRHSAAWTAWCPASDTDTVDGFQFIREISVAESPSLITLVDSPLVSSAGGLSDNKICIGYKHQWDLVSERTGEIIKLHHIDASKVNLVAALDIYEDDEAELLLCHNNTCHFQKLTEECSNEFDFQWNSVPEAIVCAFPYILAFTQDSIEIRLIINGNLVQTMVMPRLAFITSKSDIFFATTAPEFFTLRRERVRVDRLERDPSLSPPPSPHGKELTVLDRDAVKPFRIYRIPFRCLTGATTCERRCPTPSAPLHPPVLGDGEDAPGSGGAAGADVCSGRTGMHLRVSDQRYASRSCTASPTTTLPLAGLPGLPPSLGLPPRELVQGLPLAPAHLPEAEGPHQLPHHVIHQTPNNMPHYITYHTINDRLIDIKNRRYTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ86</accession>
    <name>A0A423SJ86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003291">
        <property type="protein sequence ID" value="ROT64241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ86"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="58711" checksum="624D990DEEA51981" modified="2019-05-08" version="1">MKGKRAPSHTTFPFAATLSLPIPPHLLYLHIHICSKGASTSTFAQKFINLSISFSSSTPSLHFFHLPHQLPCLPSTPLFFFSPFFLRSTTLLIFTNLLHFLHPIHFLHFVYFLCLLYLLHLLPSSSSPLPPLHPLSSSPPPPSSSSPPRPSPSPPPPPLPPLLAPPPSFSTFYTSFTSSISPTSSTPTSCTFSTSPNSITSTLHLTSNILSTHYISSNLPPPPPKPTRILHIIHFFHLHYLPLLPISSNFPPVHPPFHPIFSTFPPLHPPLFPPSLLPPNPPPLPPPPFFHLPTSPPSSTSPHLFHLLIHSIFHHRLSQPQSNPQRPPTPHQLPTSITATLPTPLAFLLSCYFPHQLPYLLPSPIYQHLHPTIPTLTSTPPILTPTSTSNNPSPPPSPLHLHILPFPPSTSPPPPRTPSLPPLPLPTSPTPPSTSSPPPSLLPPSPSPTSPPTNPSPPTPPTNPTLPTSTPPTPPTPSTSPPPPLLPPSSSPPSYPPLLLPHALTRSSSSRLHQERLRGERACLGASSDLRVSSGLYFCLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK51</accession>
    <name>A0A423SK51_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Thrombospondin II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_017440</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thrombospondin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003222">
        <property type="protein sequence ID" value="ROT64617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK51"/>
    <dbReference type="OrthoDB" id="6357843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000002">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017897">
        <property type="entry name" value="Thrombospondin_3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008859">
        <property type="entry name" value="Thrombospondin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05735">
        <property type="entry name" value="TSP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51234">
        <property type="entry name" value="TSP3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51236">
        <property type="entry name" value="TSP_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019106790" evidence="12">
        <location>
            <begin position="20"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="32"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="10">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="10">
        <location>
            <begin position="183"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="10">
        <location>
            <begin position="276"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="TSP C-terminal" evidence="14">
        <location>
            <begin position="315"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="238"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT64617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="539" mass="57698" checksum="72579E1C234A7630" modified="2019-05-08" version="1">MWTSVWLLTVAATQMPGAAILQAAVTVLVNQDVDECLVANGGCHAKAKCTNTAGSRTCSCLAGYTGNGQVCVVLKASCPVGFAGEGADCAPDSDLDGYPDTELSCSSKYCRKDNCINRPNSGQEDADGDKIGDACDADADGDGHNNNKDNCPLVANSGQSDKDNDKRGNLCDNCPDASNPSQSDIDGDGIGDKCDDDIDNDGLLNAADNCPKVANGNQADGDGDGIGDACDNCPKHPNAGQKDKDEDLLGNACDDDVDTDSDGVEDSVDNCPNNQKDTDGDGRGDACSNDLDGDKILDSDDNCIANPSVHSTDFRHLQMVALDPQTASTPPVWVVYDNGAEIHQTVNSDPAIAVGDHVMGDVDFEGTFFVEDTSDDDFVGFIFGYQSNAKFYVVSWKKGPQNWFNKAERGVTLKLVNSNTGPGTKLRDALWFTGSTANQAKMLWHDGSIGWKPKVAYRWLLHHRPDIGAMRFYLYQGTKQVMDSGNIYDGTLKGGRLGLYCFSQEEIIWSNMEYKCANGVPQEMFNDLPANLQNQVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKK0</accession>
    <name>A0A423SKK0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative nitric oxide synthase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017327</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003200">
        <property type="protein sequence ID" value="ROT64722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKK0"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048270">
        <property type="entry name" value="PNMA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45823">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45823:SF1">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14893">
        <property type="entry name" value="PNMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="43576" checksum="D36F12CD8B7506DC" modified="2019-05-08" version="1">MSKIPEPGSESGAVGEAQVILVGNGGEERAAEAGKQAPPGVMDLFRKVMSKLDKTGEDMNRLSEAMRKNHEELSYLSPDLTPPLSPSAPASPVPQCLQASPRDCQRWRKPSEFDGKVAWEAYLAQFELLAGAQGWDDHEKALQLVSGLRGAALEVLAHLTSQQRTVYSHVVGALQRRFGHHHQAEVYRARLKARVRAKGESLPQLAQELETLVRHAYPAAAEDMVTVLTRDYFVDALQDRELQLYIKQVHPEGVQVALARALELEAFLCTSVLGAAVEVPRKFYPNREFRARRTQVGESPVEQCGATQRVSLTGFQGICWRCGKKGHRWSDCPRGRRTRSPERKPISAFQPYCGSCGPYGHFSVACTASKDMQVGNEEGLDAGANSQPTLIGSYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMV0</accession>
    <name>A0A423SMV0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ankyrin repeat and SAM domain-containing protein 3 isoform X11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016507</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003078">
        <property type="protein sequence ID" value="ROT65522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMV0"/>
    <dbReference type="STRING" id="6689.A0A423SMV0"/>
    <dbReference type="OrthoDB" id="6338611at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24184:SF11">
        <property type="entry name" value="ANKYRIN REPEAT AND SOCS BOX CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24184">
        <property type="entry name" value="SI:CH211-189E2.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="165"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="4">
        <location>
            <begin position="269"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="52316" checksum="0F99DF504A421273" modified="2019-05-08" version="1">MADLEETWTERNFYDRPLSVWLQDEYGDEDFLLLDIFTAASIGCSQRVGDIIKKDKKAVGYKNKGGWTALMYASYYDHSDVVKLLLEANASVHLTNNARCNALMLAVMCGNESIVETLIKAGSILEARDNWDWTALFHAVNSGHHSVVDTLLRHKANPNSCERRTGMTPLMYGAQHGNSSIVMTLLKGGALVSLTTHQGHTAARIAQDADYPAIAAIITKWGLQGENGPSLPDGPAAVEARLSQQAQLPPRGRGNVVPSVDSARVIPTDLETLLNQIGLGSYMSVFKEQDVDLQMFLTLTDQELKECGIHKLGPRRKMTSAIARWHSNAPLWNSLECAYADKLEVEMQELGVKLTEAMETIQQTKAQVYQEHNLRVVTEGWIVEARGRLHDCHQRCQMLLEQMSVMRHCASVLSAQFSLIQPTLISPLVESIGVATAHIDALLKLTDPSVARGPSNPSSPRRNGHQGSYPNTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWJ8</accession>
    <name>A0A423SWJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002657">
        <property type="protein sequence ID" value="ROT68562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWJ8"/>
    <dbReference type="OrthoDB" id="6361750at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="552"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="610"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="752"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="841" mass="92837" checksum="FBA564D474E5B386" modified="2019-05-08" version="1">MRLNDGAFVCSTMGLAFVVLNDGLSCANDGASMLNGLSCPACNDGAFVCSWGFRVLNDGACAQRWDGMACVFRSAVRAEAPTGTKPRANERANSAINGVGKAAPERKIGRRGRQVGVVLHRRDLERNICVEIERRKIRTYGGGKPCRFLRQERCVQSLVSFHPSASSDPLFLRSFHFLSPIFLGLSLQHFRSRYSSRGTHTWNQVLSCSLPALTTFNMRMTLVLVVALALLSSASAQRPSRLQQMVRGFMDDMSDMASRIGTGMLKSINNRPGVARENRPGFPGRKRQRPVPLDDLPARQSSDNLVAPNDPQRPRPVVRQERPRLTFRQFVDGTMAGLRNLFPRLTRRNFHRSARDVQVSPPDYSPPDLNYDSGTFDLHPDPIYVHQPSPSHPTVQVTVNVYNDQNPTKDKDAPDEAPTHAPEYDLTVTHHTNHSFSVTHTPKKTDEGKGQSQQTLYPTTEHSVSSYVGNMHASPSNSYSVRRSDVFPETEWHPERHQRSEEILSPEQMQFGAQSLDMIYGYYFGDDNNGQIHDSKPLGSFRRQHVQLNRNVNDRQDFDAADEGQGYKDGFLHGFNQGFESGVKVNGNRGPSNNNKDPNHSHNSNPYNTRGSNGNRGSNNNFASQYNNNNNPSYSGQVSSSNSMVSQFSESGGEGTGTAGCGVRCLWDDLMNTLDHYSNNGGTEASKVTGASPSGGVEGHVVHQQHGSGGAYQGPSNVPQAALNPYAGNADSNTPGVSTVNTKTQNTNSYHQSMSSGRGPSQRQQSFGYRGRPFGNRRPPPGAPQFHSQRDELLPPGPPYSSHSYDLGSHDGRVRSGVGGQSREQQWNLRRRWDTHKGKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZA3</accession>
    <name>A0A423SZA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZA3"/>
    <dbReference type="OrthoDB" id="7659889at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="301" mass="32830" checksum="BEF3B48CB63992FD" modified="2019-05-08" version="1">MVMKMNIFMWFPPKYEIAFLSTCSLSSLLNTRTYTASTTRRLHKCRRGSAATERPLGCEVWCGRLASARVSPPVMEGQGRAPLTLWAFVTRYDLTHTDVNGECNDNKPLVSLAMRPEWTARDVQRELKKTLKLDQSSVDSSLVLKVRNGEGMLLPMTPTALNSTSKQPLVVEVCAPHQHVTGTESDMGALPASFRKTVEGLISNYETRVRASPFPEENLAPSHSRPRSHSAPQPPRSLPRPRGGEGAVFARVPSRFAPRGKRDASTTPSPSCRVASATQTPLGNAGGGRDGEKDGKHGLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZW9</accession>
    <name>A0A423SZW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Opsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_012020</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002522">
        <property type="protein sequence ID" value="ROT69741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZW9"/>
    <dbReference type="OrthoDB" id="9996086at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00577">
        <property type="entry name" value="OPSINRH3RH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="73"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="351"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT69741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="43233" checksum="8B620BE5AA9FA180" modified="2019-05-08" version="1">MSTGAFNATDPAAYRGGGVSFGYPQGFTLMDFVPDDVKPLIHSHWSNFPPVNPMWHYMLAGIYVVLGFLSFFGNGVVMYLFLSKKRLRSPANMFVVNLAFSDFMMMLSQFPMFVTNCLSGGYWSLGAFACRVYGFLGTVFGLTSLVTLVAIGYDRYCVIVKAFDGGHISSGKAFVIIVLCWAYSVAVSIWPFFGWNSYIPEGILTSCSFDYLSHDWNVRSFGIFLFVMCYCFPLTIIIFVYSQIVGAIRQHEKALREQAKKMNVENLRSNADAKKQSAEVRIAKVAVANVFLWLLTWTPYAYVVMIDSMDQTKVTPLVSALPALIAKTASVYNPIMFAISHPKFRLALQEAMHGSASTKRRTTTRNPRRRKRRTQNNSLKRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T080</accession>
    <name>A0A423T080_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="4">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011868</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002502">
        <property type="protein sequence ID" value="ROT69910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T080"/>
    <dbReference type="STRING" id="6689.A0A423T080"/>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF32">
        <property type="entry name" value="AMP-DEPENDENT SYNTHETASE_LIGASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="291"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT69910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="938" mass="103772" checksum="10CDF51F13B0F5C7" modified="2019-05-08" version="1">MHNTELQSTLRRSLAHSCIINPSQRQGRSAHADPTSGPRLAISRQPLIGRWPSVTPESNEKYEPKGFIAEIASERRREPRVSVPLFLEEVPYSRNTLPPLVSVEVNGLEVAALIHTACHVSFISATLVGELSMRQDVIPDTSVPPSPLSSGTGVPWLVEGKLRYVELSLRGSKHVTQLHVARDLPSDLVLGVDFLKKAQVRVNFPENCIFLPNGGQETKVRFNGLGREWQSGWAPESREMEENFDEYRNGPDQVLPATHNKTWEADGVVKLYIEEEGAMAGAPFSVHTLMQDRARDYAKHPALAVKREGAWRYWTYKEYFEESRTVAKAFIRLGLERFHGVCIMGFNSPEWLIANFGCIFAGGLCAGVYTTNSPEACRHLAENCRAQIIVVEDNACLNKFLAVKRFLPEIKAIIQWSGVPGAPGVISWAELMAIGLAEKDAELEDRLSLAAVNQCCTLIYTSGTTGPPKGVMCSQDHLTWGSSQYQANTNHELCTEVFVSYLPLSHLAAQMLDVYLACTIGATVYFAQPDALKGTLGQTLQEVRPTCFLGVPRVWEKIYERMQEAGAQVGGVKKAVATWAKYHGLNYFNALRDGRTLSTYERACNSLAKALILNKVKAAIGFNRAEKFVSGAAPISKDVLEYFMSINIPIMEGYGMSESLSICSMSYPEQDRFRLGSVGKALPQCYTKLAPVDGCKPDEGEICMKGRSVFMGYLHMPEKTSETIDDEGWLHSGDIGRFDEDGFLYITGRIKELIITAGGENIPPVLIEEAVKKELPFVSFAFLCGDRRKYLSMLLTLKAETDDTTGEPQQILTPACQALFKDLGCDVQTVAEAVAEVKENPSGPLAKAIQDGIERYNKSGAVSNAQKIQKWALLPLDFSQPTGELNNTLKLKRSFVQEKYKDIIDSMYIPNKSLDVASRAHDKGDALPDLDYDSNLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T090</accession>
    <name>A0A423T090_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vigilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002503">
        <property type="protein sequence ID" value="ROT69897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T090"/>
    <dbReference type="STRING" id="6689.A0A423T090"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="237"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="305"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="394"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="466"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="590" mass="65373" checksum="68C7F4BAC76A192C" modified="2019-05-08" version="1">MGSYFTGICSRNRPYLRDLEVDRLSIKSLEVSPSSPPSPHPPKFLHASDWLMSVHALANQNAGASRRHAGKTNNWHHQLLQLKFSKCFHPSPPHPRATREARSFDEHLRKEMSPRSELSFASHSSPDLEDDVAFAAQMCKVKDVVRKARPAPPRRRAERPLPAVKASADSVVSLPLYVAEEDRRRFLQQARKAAEKYGVKLVRPHAGNLVAPFLVQGQREAARAFIQHTEDCVRGRSDETASPDIAPEHYGKAIGKGGARLKYITEKYGVRVSVPKDRESPIAVSGQSESVRGAVREMEELVRQDLLKRRVALPVKVLPEDIGVVIGKGGCHAAQIQEEFGVRLRTQSHEHPQSPLVVEGPLDAAERAVASIQLRVAERRRLNEAYAEERRRREELRGTIPVRVEPGRVGMAIGKGAFRVRHVAQRHRVRIQLPERNKPDGQILVTGLKDDARAAVAELELMAKLKLRPEHVLVPLRVKSEEHILVLGPEGCRAAWLGREFGVRVVRPSADGPLMLEGGVEAVARAEAHVEGVIAQRRLATRPSPLPLPTLPVSLATGGRASLPVVQYWWLYALANPRAASCVPNPAILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2A7</accession>
    <name>A0A423T2A7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011091</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002404">
        <property type="protein sequence ID" value="ROT70627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2A7"/>
    <dbReference type="STRING" id="6689.A0A423T2A7"/>
    <dbReference type="OrthoDB" id="10024839at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037863">
        <property type="entry name" value="RHOGAP6/36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12635:SF7">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12635">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="195"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="783"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="798"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="823"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="839"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="854"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="901"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="970" mass="107115" checksum="4E2DF51D5326208C" modified="2019-05-08" version="1">MKGVDGGNTWSSVTGRVVSLENTSLLQFTEIERLTLQQLAIAKLQALNLGCQIRVPREQSNASAQKKRRPYLLKRKALTTGFFDSKKEEAKDGVASGQVFGLSLSKCLENERSRIREAAERAAAAAAAAAATPVSSVGEDGDAPLSRKSSHAGSQASFSSLIEGTKQSTTGSLESLNLERKRPSLVGGDLLPPGTTMPDLLTVEPSPQIPSLVNKCLKHLETNGMHTLGIFRVSSSKKRVRQLREEFDTGQEVWLNEECCPHDVATLLKEFFRDLPEPLLTRELYEPLIKTQKIRNRKLQFEALQHLIQLLPVPNRDTLYSLLNFLATVAENSVDHHTNTGETLQGNKMDSSNLATLFAPNILHTVKPGTETMSTSDMATHAEERIDVINVIRSMIDHNKELFQVSSELLDETYQHLMDTHPEALDLLLRRRCTGPDELDLDVETSSSVFEGSECSSSLPRSPTDLTHHHDFDRLRMSLEEGEGMRMLRREEVVHEGAAVAPMQQSGRRRYPDEEEDGRGRRRDKGADVPVSSASEERGWFRKREKSSSRELDRTSEERQPEKSRWFRKRDKSSSRGSEDRNFRREDSDRRRDKGKSKDEASVTGSDRRKGTDASGKGRSASKEKVESLGLRNQEEEDRGQHRKRSSSDQSVNQERLQVPEPTVRRLSSPEIDNSGVITASLRIPVPLAQGGGPLAFAQDKEIPFIEDSSTSDDKKNRQRSSPHKGGGSPRNDIARQRSGSSDSYLGQPITGTMSFQPLTKKGGDKQSHDSVLSSSSADVYTLSPSPRNTPLSDVYASGTSSPLSGAGSPPLWLSPDSGTPGLSPPNSPPPQPRRRGESSNNPIAHSVTHTFGTKPPATPSKSKSSSSVASHGLFPIGRSKTADNIKTVTHHTEGSGTTSESRDEIARETRGHRDYGGGRRYTRRRYTGERHPTGHLPDMSASNVSEGQTQLWKRWEIIASDPTEPETFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2T3</accession>
    <name>A0A423T2T3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002395">
        <property type="protein sequence ID" value="ROT70723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2T3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019561147" evidence="1">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="277" mass="27237" checksum="97CE2588A7F57341" modified="2019-05-08" version="1">MNALTLVCAFAAVAVCSAGVTHSSVLSHHVALPHSLPHDPVGVQQVPVAAVGHHAPLVTVKHHGSPLLHVAPSVHKTSVVHHAAPVAVPHAAYGAVSHSVPVVAAHGTVGVSHSAPVAVAHAAHGVSHGAVAVSRPVAVAHAAPVAVTHSVPVAVSHAAPVAVSHPAPVAVETPRSYGTFPASTGPLATVAHVAPVVHAAPAVASVAHVAHAAHAVAPVAALSHAVAPAAHVAHAVAPVAHSGVYGYSSPLRGFSYGYRTGPSVTHYAPVLSHAGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4B1</accession>
    <name>A0A423T4B1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010348</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002307">
        <property type="protein sequence ID" value="ROT71340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4B1"/>
    <dbReference type="OrthoDB" id="10037824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056707">
        <property type="entry name" value="DUF7805"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF3">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25090">
        <property type="entry name" value="DUF7805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="115"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="876" mass="96906" checksum="02B86025C8CCD6DD" modified="2019-05-08" version="1" fragment="single">VRVAHHGRLPRRLHADRGAESGRAHTRLLVGAAWGHNVYYSETSAVTLMLRVFNRIEESGPPTPGSFLLRAVAGHPVLLKVTYRFFKKEKACCATACPTTQLTAARTSPKPLFFCDKYFRELRHRKENCKVQSPNYPGLYPRNLTCYYHIRQTRVPDGKLALIRVFQRNPHLIYIKDRNAPHLSRERRMRVGSACHVLHDYLIAFDGSTTRTPVLATICKGGAPLSGITSSGPDMLLVFQASPFDFPFQDSPRRRIFGFELDVEVEFVDRESTAYVRRGADATTMVSSRGQRSGYLQAPAHSLLPNTTCSWRLLAASSEVVWLYFVHYRHALHAEMPPPAKCSNTLTIYDGDAAGEEPDALSLEKKPAGDADNTTAAPSVLGRFCRPEKLPRVCSGVHAPGPHSAPCSPAESYVSRSPALTLTLRYAAGTAPAHVEFLARYEFVDKRQWGDPTPGGGPCDRTFTLRPDRLFASPRDVFLFGRGGTRRLQCVYTFKAAKHQRIALRILRSRMGSACSTFYRQASQRFECSHGGERGAPAIWVREEPWTGVPLTRACLCNTSHSAPFHLVSYTSRLDLVFSVPAMTAAHDYTDFFFEGEYSMLDAGPTLRAAQCDESARRLSGRHGNFTVGGWPSDHCSGLPRLVTATDGSFLFLRLHGHVASESNCGVAARINVYSAGGLTPIASVCPGQRQEFTHVFSNGWRHPEELLEESFSWHNKSASQQSRRQHSQTQQETRDLLVEYVGNSTGRYMVTWVGVWRPLQTAPLSPAGADLCPHRCPEIQACLPKELWCDGDAHCPSGMDEGAGACGFLAALPWVYLAAGIILLTSLVALLVAVVLHRRRTLAGKADAAEVVENNSHSVKSATHDLLLPLEKESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4X4</accession>
    <name>A0A423T4X4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002281">
        <property type="protein sequence ID" value="ROT71549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4X4"/>
    <dbReference type="STRING" id="6689.A0A423T4X4"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="20154" checksum="7B6EE3D850039E67" modified="2019-05-08" version="1">MALRAPAVQLDEASREVGGGSNFTYYPPDSRLVVVDPNPNFARYYHAHKESSATFAAKGERMDMVPDNSVDAVVMTLVLCTIDDPGRILQQIIRGGKFYFFEHIREFDGERHRLRQKLQDLLTTTGIAPYFLEGCCLNKDMLPAIGAAGFSKVSAERFYAPIDNFVYQLVKPCLRGVAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T601</accession>
    <name>A0A423T601_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002227">
        <property type="protein sequence ID" value="ROT71932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T601"/>
    <dbReference type="OrthoDB" id="6409159at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.220.10">
        <property type="entry name" value="Ganglioside GM2 activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036846">
        <property type="entry name" value="GM2-AP_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="195" mass="22019" checksum="DF986A18EBDF20CB" modified="2019-05-08" version="1">MKIQFGEKGEVPWDVLLEAVQNEQRQQESEQFQNRKSLCSRIRKRCCDSWLTLAILVSVVLAAQAWVLLYFTMGCASVYKLGCDYSDEAWVLLSLRWLSKLRVSPDPVLIEGNITVDLNSYLGVNVDAPISADVKVERRLAGLGGWRCHALLVLGHVTMKMCASWFHFLLLSLVQTHSLGSNCHADVHSQRDIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7F4</accession>
    <name>A0A423T7F4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002165">
        <property type="protein sequence ID" value="ROT72377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7F4"/>
    <dbReference type="OrthoDB" id="6379141at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="3">
        <location>
            <begin position="531"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="704" mass="78189" checksum="3F40E5EC2AF7BFA8" modified="2019-05-08" version="1">MLVTNLPPELLLTVGNLLNDQRNATYNELKEAILRRAAPNPLTTLSSFLSSDTMDNRTPSEILRYFQRLLTRTSMTFTPDVMHSLFLKRLPADIQQILLVSDAPLEQLALKADVIIAAKTRAPSVATVFATAATVGIPYSPGRCTVRGCTEIIHTGAFTLPASLPHPFAAAQRTELQAPFTVKTPVPFTRTFREMATTETECASFPRTSSAFTVRPGCLFLPPFPHRQGGRGAPSQRFQWIFLVADVPQPIIGAVFLEHYGLSVDLQGKALIHQSGARTLAAPTLPINRATQLRHEVHHHIVTHGPPAHSRCRPLAPNKCRSAKAEFDHMMQLGIIRPSSSQWAAPLHLVKKKDGDWRPCGDYRHLNMVTAPDRYPLQHLHSSHEPSSCTVFSRIDLRFINDVTRGLEGVFAYIDILVASASEADHARHLRALFGRLQEAGVVINPGKCLFGAASLSFLGHTVTLLGIIPAQEKVTTIRKFPKPAMEKQLQKFQGMFNFYRKFVLKCAQLLKPFHVLITPNRASRNTKIKWTPPTNEAFEACKEALASATLLNHPLPEAPLNIVVDASDTAIGATLSPRQLQYSAFGRELLSAYSALRHFKPYVEAKEFHILTDHKPLTFALHSRTRCQSPREERHLDYISQFTTDIRHIQGADNETADALSRVTIAAATHADVAVDYHLVRSEHRQDASMTLLIEGQTSLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7P7</accession>
    <name>A0A423T7P7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Glutamate gated chloride channel alpha 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_009142</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002151">
        <property type="protein sequence ID" value="ROT72472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7P7"/>
    <dbReference type="OrthoDB" id="6368456at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="17">
        <location>
            <begin position="118"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="456"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT72472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="566" mass="65896" checksum="98C125E43F37172E" modified="2019-05-08" version="1">MKGTVSHGAWTDNSCRKSFKYCPVCRLVVPNYLRFRGICDSNLYDDRLILTGVKNNKPYFRGYYRSQAISLALTQCESDEFTCNNGNCIPLHEVCDRRAQCTDKSDELNCTLVLRPEGYQPSLPPEAPLSEGPLPVILNITIDSFKEIDAINSRFIVELQIRMIWKDVRLHYLNLKSDRQLNLVLEEAAREMWVPAVDFLNAENNAKSRVDSNSKITIMRTGAKEPDNVEMSREAMIYDGRYSFIRISRKYTATFACTFNFFYYPFNTDFCKMIFRVNRNNKPYVKLIRYGPGVTYDHKDKLNEFFIGRMRMVTYNSQAPYSGQQIIVEMQHLYGSQILTMFVPTTIISLIGYGTFFFKWYDFTNRIMVSLTVLLVLTQLFSQTTDMLPKTSYFKLIDIWFFGSITYTFVVIVVHTAVEYMHVYDHEIEDLHEKLQRAANFYREITPTPTPGISDAVRRFSDSDEPQSKREKKFSRNYLLPVVMKARLLWKAMQRPEAKGDRNPNFWPIVVDKLGNIVTTLVYILLNLIFWTVAFAQHVHEPLMDLDDPSYVDSVENATNRVWPVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8T8</accession>
    <name>A0A423T8T8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Paramyosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_008715</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002094">
        <property type="protein sequence ID" value="ROT72880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8T8"/>
    <dbReference type="STRING" id="6689.A0A423T8T8"/>
    <dbReference type="OrthoDB" id="6350306at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000025">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1160">
        <property type="entry name" value="Vasodilator-stimulated phosphoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="7" id="KW-0518">Myosin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="13">
        <location>
            <begin position="2"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin tail" evidence="13">
        <location>
            <begin position="258"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="348"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="21"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT72880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="580" mass="66339" checksum="D0F034C9AE440FB3" modified="2019-05-08" version="1">MTLSSQLEETKKSVENEGKERATLLGKFRNLEHDIDGLREQLDEECEAKADLMRQLSKASAEAHMWRSRYESEGIARAEELEAARMKLAARLEEAESQIEQLNMKNLNMEKSKQQISTEIEGMLISVERAQALADAAEKKQKNFDRVIGEWKMKVDDLAAELDSSQKECRNYSTEHFRIKAAYEETLEHMDSARRENKNLGDEIKDLMEQIGEGGRSLSEIEKSCKRLDIEKEELQAALEEAEAALEQEENKVLRGQKSHQRILENMQASLEAEAKNKAEALRMKKKLESDINELNIALDHANKANFDVQKQLKKSQGELKDMTLRIEDEQRLASEYREQCSMAERRAHAVSGELEESRTLLEQSDRARRQAESELSDANETISGLTNKHGSLAAAKRKLEGEMQSLQADLDEMLNEAKGSEEKAKKAMVDAARLADELRAEQEHALGQEKMRKGLEVSVKELQVRLEEVEGTAHKSGKKALAKLEARIRDLEGQLDDETRRHADAQKNLRKCERRIKELSFQSDEDKKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKYRKAQQELEASEGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA27</accession>
    <name>A0A423TA27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha 2 macroglobulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002040">
        <property type="protein sequence ID" value="ROT73304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA27"/>
    <dbReference type="STRING" id="6689.A0A423TA27"/>
    <dbReference type="OrthoDB" id="6348147at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.690">
        <property type="entry name" value="Alpha-macroglobulin, receptor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009048">
        <property type="entry name" value="A-macroglobulin_rcpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036595">
        <property type="entry name" value="A-macroglobulin_rcpt-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF171">
        <property type="entry name" value="PREGNANCY ZONE PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07677">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01361">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49410">
        <property type="entry name" value="Alpha-macroglobulin receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019073923" evidence="1">
        <location>
            <begin position="29"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-macroglobulin receptor-binding" evidence="2">
        <location>
            <begin position="291"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="43282" checksum="7760B95D65131C4E" modified="2019-05-08" version="1">MGGLQGKGSPVPLTAYVLIALLEAGAPADAPIVLQTTRCVLGDMTRDPYTIALKAYALALAGHPRYTAVLLQLLELAVEDDEGMYWEVQRMFYRSNSLAVETAGYAIMAMMANPERYLLDARKIVKWITTKRNGYGGFYSTQDTIVALQALASYETNTYEGKLDVVATVTSFSFRESEKVQQSQQFQQSQKLQYKRSVPTVGNLVHEFIINEDSKLLQQQVSLPDFPTYVKISMEGQGCAVMQAVLRYNVPVAEPSDAFSLKVDGDNAPGRDCARKRIRACSAYILPDGESNMAVIEVNLISGFIPVKDDLKAVVRRNPKVIKRYEVDGSKVSFYIEEFTAEEVCVAFNILREVEVENTKPGTVVVYDYYEPDFAVSTTYAFPYVEGCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA71</accession>
    <name>A0A423TA71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative proline-rich extensin-like protein EPR1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002033">
        <property type="protein sequence ID" value="ROT73344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA71"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="698" mass="73361" checksum="63D8F8676D555941" modified="2019-05-08" version="1">MGGWVGGRLEVLLLLLGVVVGGWWMVVVGGRLEVLLLRGVGMDGGRSLTLTPVLINPPALITCLTTCPPPVLTTCPHHLSSSTHLPSPPVLTTCPHHLSSSTHLPSPPVLINPPALTTTCAHHLSSPPALINLPSPCPHHLPHHLPSLPSTHLPSTPLTTCPHHLPSPPALTTCPHHPPALTPAHTPALTNPPALSQTHLPSPPATTVLTTCPHQPTCPHHLPSPPALHTCPSPPALTTCPHHLSSSTHLPSHLPSPPALTTPHHLPSPPALTLPSPPALTHLPSTTVPSPRCPHHLPSPPALTTSSPTALTTCLTTCLSLPTCPHHLPHLNHLPHHLFLHASTTCLLTHPALTTCPSPPVLTTCPHQPTCPHHLSSSPTWPLTTFHHLSFIPTCLTTCPHHPHHLPLTTCPHQPPAPHTCPLQTHLPSPPVLTTHLPSTTCPHHLPSPPVTHQPNRLPVTTCPNPPVLINHLPSPPHHHLLTTVSPLPSPTLPFTTCPSPTALTTCPHHLQPTCPHHPPALTPALTTCPCHQHLPSPLMSSSPHCPPPALTTCSHQPTCPHHLPLTTPALTTCHQTPASPPDLNLPALTTCPCPHHLPSSPPALTTWPAPPLSPPALPPASPPALTTCPHTCSPSSTYLPSPPVLINPPALINPPALTPALNHLRPHQPSPALTTCPHQPTCPHHLAACSLMAPAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAA9</accession>
    <name>A0A423TAA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">A-kinase anchor protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_008168</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAA9"/>
    <dbReference type="STRING" id="6689.A0A423TAA9"/>
    <dbReference type="OrthoDB" id="28045at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035023">
        <property type="term" value="P:regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.900.10:FF:000004">
        <property type="entry name" value="Rho guanine nucleotide exchange factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041020">
        <property type="entry name" value="PH_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051632">
        <property type="entry name" value="Rho_GEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13944">
        <property type="entry name" value="AGAP007712-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13944:SF21">
        <property type="entry name" value="CYSTS, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17838">
        <property type="entry name" value="PH_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DH" evidence="11">
        <location>
            <begin position="181"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="611"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="851"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="932"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1039"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="336"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="758"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="79"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="867"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="935"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1051"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1075"/>
            <end position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT73396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1105" mass="123756" checksum="C4E8C7DFE79C1C41" modified="2019-05-08" version="1">MAQRKITRGTLRSTYEKIKSRSLNDLSEIFLERPKARDGGAGEPRPEKGEWASPASSHEQAKEGREQRKESKRKKKDRRTSVDESRAMLEQEGEREPKEACRRTDAADGAARSEDLGSPTQDDILEVNSASMESLDDGNEEPSLDDIDADPELRLLDKEPELWVHTVEKEVVDKLTEKQVKKQEHIYELIITEKHHCRMLKVMQKVFAEGMARELNMQDSRIKRIFPCLDELITIHCSFLWRLRQRQRSNKYIETIGDLLVDQFLGDNAQGLKDAYGQFCSQHQDAVSYYKDILKTDRRFQAFIRQKSNHPLMKKKGIPECILFVTHRVTKYPLMLEALMKYSKDQEEELSTLKKALDLVKDILVNINAQVAEKEREQRLLEIYHKIDAKSSALYKEQKFKKSDFFSRSRKLKFEGSAILSQQKGKPILVQVVVLSDLVFFLLENNQKYYFFSPDSKQAGVIPLDKLIVREKAGEGSRAIYLIYSKNTAEIEAIDQCPDEEDMGDNSSENSKLQEANSEKIREILGILQHKDKDLARICEDKMNAVTELLELLGNDEFPPTPQYRALLDEHHLDHNAARDLQINSLMEALRLVSGACGWGSNLARSVSSVGEHQSDAYVSPSLPKRAETFGGFDNPNKDASGHPQKQSGGKKKKDSRMSLTSTGTGESDIIESLKNRRPSGSTLAVRSSQDNLSIVSTLSGDSSSQQQHQAVAAKLIYWLQTSLVLSQHHLTQFDMLRSKLVVGGASVDGRFRHSQKLEELRNIQEQISHERAQWMKERDAQEKWIAEKKIELQKKEEHLRSEQQDVQQQRELLYRKLEALKAQGIILSPTLTVLTTTPPTHAVHEEHLAGNVSGSAGDGGQMTQGSPHSSPTSTAAPTRPRTDHKHRNSTASIANLIKRDSNQSLPTHLISAANQQKASISVKQQLPMKLAKLGSSSSTGSSSSSGGGGASSPNQDRLDHHRSHISPGASGGVQQMLPLKLSQGPNEGKGSRITVGTSAWLLLHHPLSPHQVHPTNAQGRPLPRYRMGLQLSVLGTRSHCHHHRPGARATRTNTYPKLTSKPSVPTTRANTTPEGSQEGSGVGSSTRPGQRIKDPDTNQDIIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBK1</accession>
    <name>A0A423TBK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative SH3 domain-binding protein 5-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007663</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SH3BP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001978">
        <property type="protein sequence ID" value="ROT73859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBK1"/>
    <dbReference type="STRING" id="6689.A0A423TBK1"/>
    <dbReference type="OrthoDB" id="446789at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007940">
        <property type="entry name" value="SH3BP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19423">
        <property type="entry name" value="SH3 DOMAIN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19423:SF1">
        <property type="entry name" value="SH3 DOMAIN-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05276">
        <property type="entry name" value="SH3BP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="291"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="370"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="507"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="90"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="315"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="545" mass="60678" checksum="7CC8EB72CFC33537" modified="2019-05-08" version="1">MAAVEEEQLDPRVQIELEKLNTATDDINKLEAKLEEANNVFRTTLTESTARLKALAKKLGSCIEKARPYYEALELARSSQLDCQRAAVQYQRANALHQAAKETIALAEERFVNSRHEHWQFDSAWQEMLNHATIKVMEAEAQKAASEREHMRRAAAFTQAEQRVQQLQRGLKSSINKSLVYFEEKANVQSQLQAQKERVQQLQRAITASKTSYAQSLRSLEQISEEIHEQRRCRLPREPGVGAEITPPEPDDNQTFDHSAKTFTPLEEITAQEEKYWESLREKLEKLKVDNGEQAASAEDEASDSECFDGRERTVTGSSCTSNPELERGLPMERVVSGESSAASESDEAQSPTEGKDLCLEEIIILDTTEDPELKLGSDKECVGSQADAEIKGEEEPMTSRKSPVGGDAIMIISLDGSCDESNANKSPREERTTGMAPTDGYSNDKGSDMIYSDNGIGNELVQEGFKENMNTTSLLSGYISEDIASNKNGKDDLEDTEVEEIILELDDESEEEETRECNSASPPPTMCQPIKGLSIIPEGIESHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCP1</accession>
    <name>A0A423TCP1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Phosphatidylinositol 3-kinase catalytic subunit type 3</fullName>
            <ecNumber evidence="1 8">2.7.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_007286</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12709"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.137"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:12710"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.137" evidence="1 8"/>
    <dbReference type="EMBL" id="QCYY01001922">
        <property type="protein sequence ID" value="ROT74215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCP1"/>
    <dbReference type="STRING" id="6689.A0A423TCP1"/>
    <dbReference type="OrthoDB" id="67688at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016303">
        <property type="term" value="F:1-phosphatidylinositol-3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08397">
        <property type="entry name" value="C2_PI3K_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00870">
        <property type="entry name" value="PI3Ka_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00896">
        <property type="entry name" value="PI3Kc_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 3-kinase catalytic subunit type 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 3-kinase catalytic subunit type 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057756">
        <property type="entry name" value="PI3-kinase_type3/VPS34_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002420">
        <property type="entry name" value="PI3K-type_C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008290">
        <property type="entry name" value="PI3K_Vps34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF7">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00792">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000587">
        <property type="entry name" value="PI3K_Vps34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00142">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51547">
        <property type="entry name" value="C2_PI3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2 PI3K-type" evidence="13">
        <location>
            <begin position="36"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="PIK helical" evidence="12">
        <location>
            <begin position="279"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="11">
        <location>
            <begin position="620"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="416"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="418"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT74215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="902" mass="102815" checksum="BC463ED35EC439A8" modified="2019-05-08" version="1">MEPDTDKFWYVRSCDLDAEIQVKIGNLDGKRDNPNYEALLKDSLLKYSGLYQAGCSDLYVTCQVICDGRQLTLPVRTSYKSFSARWSWNEWLTLPLKFRDLPRNALLALTVYDSLGPRRIERVGGTTISFFGKQGVFRQGLHDLRLWPGRVGDETTPGKGHDRGKDQMVRLAKLAKKHRNGQMMKVDWLDRLTFREIEVINEHEKRSSNAMYLMVEFPRVEHEGVIYSVVWWERGGEVEYRHRSAGSVVRMPDPEIGLENLQEAKHHRLARSLRSGVTDRDLKPNLAIRDALHTIVDYPPTKQLTSDEQDTVWKYRFYLSSQKRALTKFLKCVNWKLTGEAKQAIELLNRWAPPDADDALELLGPGFTHPEVRRYAVKRLSHASDEDLLLYLLQLVQALKYEAIEGSSSLLADVEGGGVEKVEDRGSEKGEKGMTTTTSNDSDQDPKTDSMETQKISPTTPNQTQDSNQLRDPKLIASMDIDPKGLDLASFLIQRATKNPTLANYLYWYLIVECERDEPGLKHEAKVVEMYEWVVRRFRAALWAGGRAARATRRDLARQTHFLEQLVALVKVVAKESNRVRRIEKLQSLLADPAAFKVNFSAFNPLRLPLDPEVIVTGIVPEKATLFKSALEPSRLTFVDVEGKEYVAIFKHGDDLRQDQLIIQMLTLMDRLLRRENLDLRLTPYKVLATSSRHGFVQFVESLSVAEVLRTEGSILNFFRRHAPSETGPQGISSEVMECYIKSCAGYCVMTYLLGVGDRHLDNLLLTKDGNLFHIDFGYILGRDPKPLPPPMKLSKEMVEGMGGQQAESYHEFRRLCYTAFHQLRRHANLILNLFSLMVDANVPDIALENDKAVKKVEDKFRLDLSDEEGASFVQGLIDDSVNAVVAVVVEQLHKFAQYIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDN3</accession>
    <name>A0A423TDN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006914</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001877">
        <property type="protein sequence ID" value="ROT74579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDN3"/>
    <dbReference type="STRING" id="6689.A0A423TDN3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030020">
        <property type="term" value="F:extracellular matrix structural constituent conferring tensile strength"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1082">
        <property type="entry name" value="COLLAGEN TRIPLE HELIX REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="26268" checksum="B64445D7138527A1" modified="2019-05-08" version="1">MHTEATIAASRQLILTATLQGEKGERGIRGRRGRLGSPGLSGAIGDLGLPGWPGSPGRPGPRGLPGFGIKGEAGAPGLPGPPGPPGPPGLLAFDSGHSDTFSSAKLRSNPRKLQGPPGPAGPPGPPGPPGSPGQGRSGRINTIPGPPGPQGPPGPQGPPGPQGSPGPAGLPDWPGLPNRGQEQLEEHSGISHGIQVPYIPGSLGKINSEEVTSEELNPEEVILEEVTSEERNPKEVTSEELNSEEVTSEELDPEEGILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-09-13" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF04</accession>
    <name>A0A423TF04_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleotidyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006437</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001816">
        <property type="protein sequence ID" value="ROT75038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF04"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.90">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12731" checksum="A2C5981F5B3D48AB" modified="2019-05-08" version="1">MDIHVKNDFFAKLIPHRVDAGVKQNVKRNAETVCDFADRLQKTFHNQNFLAGADVMHSGSAYEGLSVKPKTDFDVIVVLALKCLEDDFEWAGERASGRRTKGIADSFYLGGLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGS6</accession>
    <name>A0A423TGS6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001740">
        <property type="protein sequence ID" value="ROT75714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGS6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="48314" checksum="4DC681EE3E6B046B" modified="2019-05-08" version="1">MLDLPLGGEEDSNARPSPWRRRFRCSTFPLEAKIQCSTFPWRRRRFSSTFPLEAKKIQMLDLPLEAKKIQLDLPLEAKKIQMLDLPLAKIQMLDLPLGGRFQMLDLPRRRFARPPLGGEEDSDARPSPWRQRFRCSTFPWRREDSDARPSPWSEEDSDARPSLWRRRRFRCSTFPWRRRFRCRPSPWRRRFRCSTFPLEAKKIQMLDLPLEAKKIQMLDLPLGGEEDSDARPSLGGEEDSDARPSPWRRRDSDARPSPWRRRRFRCSTPLGGEEIQMLDLPLGGDSDARPSLGGEEIQMLDLPLGAKKIQMLDLPLGGEEFSTFPWRRRFRCSTFPLEARIQMLDLPLGGEEDSDARPSPWRRRFRCEGEEIQMLDLARRRFMTFPLRRRFRCSTFPLERRRFNARPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIL5</accession>
    <name>A0A423TIL5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative nucleolar GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005177</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIL5"/>
    <dbReference type="STRING" id="6689.A0A423TIL5"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1190:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="169"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="55090" checksum="AD8A8CA768B9B1EB" modified="2019-05-08" version="1">MSHYNFKKITTVPPSKDFINIMLSKTQRKTPTVVHKRFKISRIRRFYMRKVKYTQQTIHDKLTAILTEFPKLEDLHPFYADLLNTLYNKDHYKLSLGQLNVARHLVDKVASDYTKLLKYGDSLYRCKQLKRAALGRMVTIMKKQGPPLKYLEDVRQHLSRLPSIDPNTRTLLLCGCPNAGKSSFINLITRADVEVQPYAFTTKSLYVGHTDYEYLRWQVIDTPGVLDRPFDEMNTIELQAITALAHIRAAVIFFLDVSEMCDMEIGQQLKIFESIKPLFVNKPLIVACNKTDVITLRELKEKSPEKFNLISALEEEKIPILEMSTLTQDGVMEVKKEACDRLLAQRVDLKMRTKKADSILNRVHVAMPALRDRKRRAPYIPEQVKKIKIMEEEGMVPSKRLERHLEEELMDDYSLDLNKNKDLANEEWKYDKIPHFWNGHNIADFIDPDIEKVEARGLMDISAMNSSLTPPVMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJR9</accession>
    <name>A0A423TJR9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">I-type lysozyme-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001631">
        <property type="protein sequence ID" value="ROT76627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJR9"/>
    <dbReference type="OrthoDB" id="6337871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="890" mass="93602" checksum="2CD77E1B4C3711A6" modified="2019-05-08" version="1">MPENVCQNNGWGEVCGPWSITKPYWTDAYKPGGDYYTCVASWDCNEALLPKEVRTNPTLNYTQRVRPTHALMSVGHGASIRTTPRTTGISASEAATSSRIVGHPRRVQGGDVIPYCGASSALLGRRRHPVSWGILGASGAATSSRIVEHPRRFWDGDVIPYRGASSALLGRPRHPVASSALLGGHVIRIVGILGASGAATSSRIVGHPQRVQGGDVIPHCGASSALLGRPRHPVSWSILGDSAYRGASSALLGGHVIPYRGASSAILGRPRHPVSWRILGDSGAVTSSRIVGHPRRFSGCDVIPYRGASSALLGRPRHPVSWGILGASGAATSSRIVGHPRRFWGGHVIPYRGASSALLGRPRHPVSWGILGTSGAATSSRIVAHPRRIWGGHVIPYGGASSALLGRPPHPVSWGILGASRHPVSWGILGASGPATSSVSWGILGASGPATSSRIVILGASGAATSSRGASSRFWGGDVIPYRGHPRASGRRRHPYHGASSARAGRRRHPVSSSAILEATSSCIVGILGASGAATSSRMWGILGVLGRPRHPVSWGILGACRAATSSRIVGHPRRFWGGTSSRIVGILGASGAATSSRIVGHPRACRAATSSRIVAHPRRIWGGHVIPYRGASSALLGRPRHPVSWASSALLGGQFIRIVGILGASGRPRHPVSWGILGASGAATSSRIVAHPRRFWGGDVIPYRGASSVLLGRRRHPVSWGIVGACRAATSSRIVRHPWRFWNRDVIPYRGASSAILGRPRHPYRGASGRPPYRGASGRPRHPVSWGILGASEAATSSHIMGHPQRVQAGDVIPYHGASSTHLGQPRHPVSWGILGDSGAATSSRIVGHPRRPARHPVSWRFWGGHVIPYRGASGAATSSRIVGHPRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMD0</accession>
    <name>A0A423TMD0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001503">
        <property type="protein sequence ID" value="ROT77621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMD0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="867"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="615"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="922" mass="100051" checksum="24214E95EE9FBB72" modified="2019-05-08" version="1">MGSCAVRPPPRTQPQRAVGEALEPYPLRARWWGSLAVAAAWLSLLPAHAHGRRQEARRQVRRALNAILGERARGAGVGGAGGNRDDGKRLRRRNIPKVLDVAASPAAGTGLREAVKSVRKAVDAGRIRLKSILKKVTLQQLLKICDLVEAAGEPLPPDATCAKRVSQCAWGSRAVRSQDPLACLSVGFTVPLPGSSASPARNTGALEVTHHGRGASGKGPQKDHEEATSEQCEAYLSDAEVEYVMGPPRGEEAEEPQVVAAAEGTPEENKAHFQHTNESRPNVKKPGSIACDFTLDISGLNPFDDCDDQTDGDDTISPSDQHSKQDKATLTRKVSSGCEGGNAAPDCLAFPVSGPGNCSPRGLEDSENRDPEAFCKDVEPAEERPVVAVMKPLPPNANGMQRYIIEHIIQQTSPCKGGHHFISLDSFVSEKTNKHNSVDAGSQRTIWSYEDEMLYQMNEMDGGFPSLGQGQTQKEVKVRTESSAACTNSSEEASSALSQSVSIISDKAANDGYKWIGNVAEIGGKTDIQQGDGQPVGDNLSQELCFTPQARQDTSRDDVDVHDDSYIIPSFASSLIPSRPTDPLGRHMPILNLTPPLTPSFSWAPKAKPPDAYSGTGTEGSSHCLPSSDLKSTGGRDEEVPHTPHSHNDEGWTCRKVTGTENMICVRLDARHRVGESTLASIFLVCLLEQDDGRVTEMLFTVPVPWFLKYTGIQTSGEGSFSKVLDKLHPQASFTRGHASKTSTVQQHRNMQQSYSAARGSPPKDPAQEREIDLLASYVLLGSPKLHDASSILEMIEEISPLPKELASNDSKRKFRTAIEFEETETRTKRARGTARIDKEVRKISDTPAHPVSLAFNVRTPSWILGHSFRPGPNSDPGHLHRKAPPSSPKLSRKVISHGRVRQFGARKPRHGGRSAKKRLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNJ4</accession>
    <name>A0A423TNJ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-oxoprolinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_003267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001445">
        <property type="protein sequence ID" value="ROT78044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNJ4"/>
    <dbReference type="STRING" id="6689.A0A423TNJ4"/>
    <dbReference type="OrthoDB" id="3643at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120013">
        <property type="term" value="F:lipid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049517">
        <property type="entry name" value="ACX-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365:SF2">
        <property type="entry name" value="5-OXOPROLINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="5-OXOPROLINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19278">
        <property type="entry name" value="Hydant_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="681"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase A/oxoprolinase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Acetophenone carboxylase-like C-terminal" evidence="5">
        <location>
            <begin position="181"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase B/oxoprolinase" evidence="3">
        <location>
            <begin position="366"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="Glycolipid transfer protein" evidence="4">
        <location>
            <begin position="847"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1040" mass="114970" checksum="903BD2D55FA5A46E" modified="2019-05-08" version="1">MFVVGPDSAGAHPGPVCYKKGGPLAVTDANLVLGRLLPHYFPKIFGPQENEPLDKDSVIKAFKKITNEVNAHRSTQQLNIEEVAMGFIRVANEAMCRPIRALTQAKGHDTSQHALAVFGGAGGQHACAVARSLGMKTVMIHKYAGILSAFGMALADVVHEAQEPCAKNYDPDNFVYFESRLSALENECVEALMGQGFSRANIACEPFLHLRYQGTDCALMVTPLKEKMQGRQKSYCYVDFQSAFLERYKREFGFVIDDRDIVVDDIRVRGVGKSQISIEDTLPQATEEPLLETVTKVYFEEGYQDTNVYLLECLAPGHVIPGPAIIMDKLSTILIEPGCTGHITAQGDVRIEIGSLKKHIIGTELDAIQLSIFSHRFMSLAEQMGRILQRTSISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQYQLQVLGDSLKDGDVLLSNHPSAGGSHLPDLTVITPVFRKGVRKPVFYVASRGHHADIGGITPGSMPPHSTSIHQEGAVFLTFKLVDQGVFQEKKLIEALNAPGKIEGSSGTRNLRDNLSDLRAQVAANHKGIQLVNELIDYYTLDVVQAYMGHIQTSAKLGVQDLLREVGSRVRMKTGSSSLHAIDYMDDGSPIELNVDIDVERGTAVFDFRRQELWREYEGLPGARCSGTSSLKESPVQGARMPRLVLRVLVLFLMLFLLVPAVMMIVWLLVGLATSPVVYPLENIDVEADDLSLLAEEPAYALVEEFLESSEDSEVMRLQLASAMEEASKDIQQIVASVSDEADSAPLNIDVEEEVHLLKDIMSGTLEEHDPHRPEEASEGEAIHPSQMKPTMLQLLYVNILRCRSHGDIVLAEYIRMYRLLNAFLSNFGSFAAVQTQMLEDRIRNLEIRHQGVNREEYQSLSSMIRFEDAAGTVGDIDPVSGTILFTCLQRHLQYLSLALHAIIPLPRDEPLLHPFESAYRTVLASHHNWFVEKFYLVGLAMLPSKEQAVAHLRASQGEYVSMEDLMSSLRLVVRELDELTEATEVVLETSGVLGRIPTQVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNL5</accession>
    <name>A0A423TNL5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat domain-containing protein 27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001448">
        <property type="protein sequence ID" value="ROT78022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNL5"/>
    <dbReference type="STRING" id="6689.A0A423TNL5"/>
    <dbReference type="OrthoDB" id="411646at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048812">
        <property type="term" value="P:neuron projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF2">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="1">
        <location>
            <begin position="243"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="45644" checksum="A86515DB93E8206A" modified="2019-05-08" version="1">MERYDEDLNENSFFQVLRGEYVEVFERAVEAGWILCVPRAGALPKYALAQDDILGHILVPSDELPETHFRTLTDRGVVVKGNLLTLENEVSNPHSVHILFDEVFYDEDMRKYKVLCLEDPLYASHALASSSSCDLVMLFSLRDCIDLLWTEGGGEEALKRLDSLVQQFLDKNPNLEEETLQNLRDLVSELFSEAIQVTLSDHRLKHKTKEDQYLLDSIKLSVETYLLHGIYKKLMKGITACTSGDDARLNRIIRNLSDLQVRDLDIDPKLSSSLTKSKFEIVNIEGYSTPLGKLGCLKRAISIVVSQGGVVSSDELLPILMFLVVKSNLPNWFAHLSFLKLFRFSAAGADSGEQSFNISSLEAAIQHISSGALFGNTSPEADCMLQVESNSLAQSMEEALGYNGGNELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNQ2</accession>
    <name>A0A423TNQ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenylate cyclase</fullName>
            <ecNumber evidence="4">4.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C7M84_003208</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001435">
        <property type="protein sequence ID" value="ROT78083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNQ2"/>
    <dbReference type="STRING" id="6689.A0A423TNQ2"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000001">
        <property type="entry name" value="Adenylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009398">
        <property type="entry name" value="Adcy_conserved_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06327">
        <property type="entry name" value="Adcy_cons_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="768"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="19">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="19">
        <location>
            <begin position="855"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="100"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="543"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="646"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1075"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1124"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="555"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1134"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ROT78083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1152" mass="127569" checksum="A51FD44EC1A1E57C" modified="2019-05-08" version="1">MRIGIHSGAVLCGVLGLRKWQFDVWSYDVTLANHMESGGIPGRVHVSKATVECLNGVYEVEPGHGWTRDQYLKDHGVETFLIKREEPLRPRRRGPRFSRSRLWSEDERNTSASQSLREARIGSNATTVSNSQLQRLPTVPTTPTTPSDDKDDDSVNSSPATPDHTDANHNGNHIGESAMSHSSSSSSTSSSTTTPTESADDKEKASDGDASDSNSPTPSPTPLEDENTTDWTPEIPFGNLKYYAGVWSSAAHYSLALRKQKKFSSQTSLEMDWEDEAFLEEEFPEGLEDEDEEAEVTQFTNPTSTFTQEVDNLMDNSIEIESNKRMRAEHMNPFTLTFKDPEMEEMYHQVRADLLKSNVVCTCVIWVLIAVCQAIVVPENSRSALVLPFLVASTLLAAGLLLVMSEEFPRLPKTLRRLSTRLARATLGRKVFVCALIAIIAVPSMLTLILVCDDLNCCTSCHVDNQTYGIPLSLMHVANPTNIEISPPPGQGDTVVKDSADKAPLSLLLSHAPRHVVQESSYTEDAGNHYHAGNKLGHELFLQPQEGGVVPRGRSGRESLRERRSVNHGAGHREAESWAYQPHADSGDVFPSLSVASGTRTSSDESFAVLQRYRSLTLQKSASEQASGVQTDGPKRIRRRGSKLLVGGSEHDNNSFSGASAAGFQTDMPKTTRKTPYPDVEETSSTAQPDALEECCRTMYPQYFVYTWVLCMVALASFLKLNYLVKTIVLVFMVTCYGVLILKFRSLFYMHDGEPDPSHSVVTPSSVISLPARMGVLLVLFFFMVTYHGRLVEITSRLDFVWKQQAVRELADMGECRQYNNQLLKNILPDHVASYFLSEDRKGEELFSKAYDNVGVLFASIPNFTQFYSEDVNRGMECIRLLNEIIADFDELLDEDRFSCIEKIKTIGSTYMATSGLNPTAKDAEDCHAHLCALVDFALEMKARLEDVNKHSFNNFKLRVGISHGPLVGGVIGAKKPVFDVWGNTVNEASRMDSTGANDTIQIPKETAQILNFRGFRLQCRGKIAVKGKGEMDTYFVLGRKASARANFTRHPSTYNSLAAVVYGMVQARKKQTIKRSNTTVRRDRQRKVSPSEGNASCSGVGGGGGVRDITPGLTRRATRLERTVTSHHNLRSLAKDDHRPEASAKSQEEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRW4</accession>
    <name>A0A423TRW4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rabenosyn-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001275">
        <property type="protein sequence ID" value="ROT79205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRW4"/>
    <dbReference type="STRING" id="6689.A0A423TRW4"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.20">
        <property type="entry name" value="Rabenosyn, Rab binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052727">
        <property type="entry name" value="Rab4/Rab5_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021565">
        <property type="entry name" value="Rbsn_Rab-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510">
        <property type="entry name" value="FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13510:SF44">
        <property type="entry name" value="RABENOSYN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11464">
        <property type="entry name" value="Rbsn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rabenosyn Rab binding" evidence="2">
        <location>
            <begin position="278"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="325" mass="36851" checksum="0FAE1997BB435C93" modified="2019-05-08" version="1">MTSFLAGISGLRRSGSQGSLNSLLSVMDSMTSEQHFRVCRHCMVRLQARDNQVEQRTSKPTLSLYYEKLMEYRSLLERLLPQYVQMAESLSAGETTYNLQDAEELRMKILKTGDNLNSMAQKIRNLGIGSQDVTDGAASSIPLGARQELLQRRIFSTSSGFLKEHILSLPKLPTFHELKETQERRRLEAEARLAAEKEAMRQAEERASEILRRRDKESKDSPRTTPNRSSSSNTPSRSSSSTPVSFSTSRKKQSDEVVVDTGWGPNLCPPNVTETDDPMIQQMNNLRNYIKQAREANRYDAVATLEANLKELQGEYKKQQRLMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWX7</accession>
    <name>A0A423TWX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001047">
        <property type="protein sequence ID" value="ROT80940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWX7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="39749" checksum="0F6B5368A743843D" modified="2019-05-08" version="1">MQMNVPLPLASPTLSPLLSSSPHSPDLSLLLLSPFSFPSLSPFPPLSSSPTLPSSLLFPSLPPSLTLPISLLLLTLSLPSPSSPSLTLPLLPSPLLSSLLFLPSLLSPLPPSLLSPLLSSPHSPLSLPLPTSLLFPFPPPSLSSLPSYRPFPLILFFSSPHIYYIFPSASLSFLFSFIHSFCFPSFVGHSTQILYLYLLFPFSLALFLARSFPSLLLTPFLTSSLLLPLSLPLLPLSLPLPLTCRFPTSLPPPIPFSLPPSLPPLPLSLLHPPSPPPFSTSLPPSIRSPCFLSSSPPLPNSSPSLTLSLPPPLPPFSLSSSPLFLTLLPPSPSSHSLPPLLPFNQLPLSLPPPPLSLPPSLPPFALSLLPPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1C6</accession>
    <name>A0A423U1C6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoinositide 3-kinase adapter protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000813">
        <property type="protein sequence ID" value="ROT82513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1C6"/>
    <dbReference type="STRING" id="6689.A0A423U1C6"/>
    <dbReference type="OrthoDB" id="6351770at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005104">
        <property type="term" value="F:fibroblast growth factor receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005068">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052446">
        <property type="entry name" value="B-cell_PI3K-Signaling_Adptrs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017893">
        <property type="entry name" value="DBB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16267">
        <property type="entry name" value="BANK1/PIK3AP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16267:SF11">
        <property type="entry name" value="STUMPS, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14545">
        <property type="entry name" value="DBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01282">
        <property type="entry name" value="DBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51376">
        <property type="entry name" value="DBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DBB" evidence="2">
        <location>
            <begin position="113"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="701" mass="78029" checksum="19E97C1DAA0D15B8" modified="2019-05-08" version="1">MELLQRMTLKSAKLQIVILSPHFMEHIANHARSELGHVFKPKKVLCLLLNVDNSSFTPAHLSVLYSYKEWQHLTVRSEDMSFVQEVIHKATSILINSEVYSGYRDESLARFKVIPRKITLTHSQVYIIMTDEVKEEVVISVNSANKEPVIIKKWRLQNPYTLSFQMPESYLETSALLYIEVSVNGKSQGSRQVKCERNMDTLSQILSNSKNPIDLMCQALNLNPLNNDLDLCLAKNFSMRIPPSRCADDDNEKGSSVFPTWIHFSAYYGLKTFTWALLEAPGGRCALSIPNCDGDTPSLLAFKSGYLTLAQALETEMICSKSRGVSSPQRMKKTGIKKTHTATYNNPPPPRPLRSNYDTLPAPRLVSPSNSPPAPSGASSESSVSVTPPPTMTPPISSPQLVEEDNSSSYIEEGCHASQQSLPSLPSALNNTDFVLDPKSHSLKEVVESYLNMNVTGRHGKHEECKNFYTEVTKFIKDKRENKTDESSSEVDSSKGTTDASNQEPSTTVMADQRSEDTVSESESGATYMTASDITDSTNRPTTNLVRHFVGLLGGTASDSEEEKNCHSTVANGRIGARSHEPSPVSAAEAFSPTIEVSIVRKLSLNDGAQNAAIKERPPVPAPFPVYSDDEEDNYLDPTRINTPPRYQILMNQKPLSKGNDIQYYKFGVDHPPRRIALKILKPQKRDEEDEDNYEDLNDMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5U3</accession>
    <name>A0A423U5U3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000597">
        <property type="protein sequence ID" value="ROT84080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5U3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="440" mass="48760" checksum="3ED465B06BF69617" modified="2019-05-08" version="1">MGAQDTYTASRCGVGFMGAQDTYTLHVWGLDSWGHRTHTPLHGEGMDSWGTGHIHRFTVRGWIHGGTGHIHRFTVALDSWGAQDTYTASRCGVGFMGHRTHTRFTVRGLDSWGHRTHTPLHGEGLDSWGHRTHTPLHGEGDGFMGAQDTYTASHGGTGHIHRFTVRGLDSWGHRTHTPLHVWGLDSWGHRTHTPLHGWGLDSWGHRTHTPLHVWGLDSWGTGHIHRFTVWGLDSWGTGHIHRFTVRGLDSWGTGHIHRFTGVGLDSWGHRTHTRFTVGVGFMGHRTHTPLHGVGVGFMGAQDTYTASRWGMDSWGHRTHTPLQRVGVGFMGHRTHTPLHGGGWIHGGTGTHTPLHGVGMDSWGTGHIHRFTCGGGFMGAQDTYTASRCGGWIHGAQDTYTASRCGVGFMGHRTHTRFTDSWGHRTHRFTHGAQDTYTASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U656</accession>
    <name>A0A423U656_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000584">
        <property type="protein sequence ID" value="ROT84193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U656"/>
    <dbReference type="STRING" id="6689.A0A423U656"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
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        <location>
            <begin position="86"/>
            <end position="120"/>
        </location>
    </feature>
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        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
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        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="499" mass="54450" checksum="BE882FBD439CE306" modified="2019-05-08" version="1">MQRGQPRRQLPLRPSQATSPTTPTSQATRQLPLRDIPGNYDFISGNFPYDTSISGNFPYDTYISGNFPYDTYISGNFPYDTSISGNYDTPSQATPLLSQATSPTTPPSQATSPTTPPSQATATAALRHLHLQFQLTTRHLGKQPLRHTTPLRQTTPNSLRTGQLPLSLRQLPLRLPVSSLRHLRQSSPTTPHLSLPLRTNLRLSPTTPTSQDLRHLSSQATSPTTPPSQATSLRPTTPHISGNFPTTPPSQATSLRHLIIYTTSSGNFPTTPTISGQLPYDSISGNFPYDTSISGNFPYDTSIQATSLRHLPSQATSLYDTSSQATSLYDTSILRRTFTTRPYISGNFPYDTSISGNFTGNNFPTTPPLRHTIISGNFPYDTSISGNFPTTPTHSLRHLHLRHFPLHLRQLPLRHLHLRQLPLRPTTPTSQATSPTTPPSQATSPTTPPSQANFPTTPPSQATSPTTPPSQANFPTTPPSQATSGLHLKTSPTTPRQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U684</accession>
    <name>A0A423U684_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000579">
        <property type="protein sequence ID" value="ROT84230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U684"/>
    <dbReference type="OrthoDB" id="6363954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="677"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="722"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="753"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="847" mass="93855" checksum="6B307D28BDBDC8C5" modified="2019-05-08" version="1">MSNNPSSNQKSQALAPGSILTVNTTRTRGTKFLLNQMLLENQQKEQHNSQATPPGSRISTPVYACSPVTRFIKIVPPINPPENCNIVLPKKKKRKKAITLTQHLVEIDPVQNREDLEKDPVPSKEAPVEEVIEKENSEELNNSILLPFGRRKKRKRKRKKKDCAQESPTGDEVYDVNMDESRDIIAVDMEVDKGEDAPEKHTENIRVPLYYESKDTKGKNKSTKNILKRQVENIPTDKSHSSHSPKNITPSLPQPSTTKTVPVTQLESSLSSQNSSELQSTSSQSSIVLSSDTPPPEVTKENSGTSELTAGTQTQAIFQNKEYQGHGSSQKRDTDVLSLPSPEILVYCSGSESDTPEQRSSVKTPKHIPERKRTITRKQSKESQSPKQRRKETANEAVQNVITVNIDESSPEEQHQKDLASLNVKSVVPVDENTLPRKVTTSQARTTSDTNTPKMKPQSSVWIQKATRADLSTPSQTSQPFPEISPCSEAEYSPLLPASQNSAFQTPRNRGKLTKLSLSQRKKILNNALSQDSGSPAVAKVKRKLDQPTPHNVSEGFMPSCSPELENSEVGQFVGSKKLRVRFWEKDDDDEEVRVLKIQQSEPPAKDVVFSMSLLGTVPETSHEKSPVATTAVPKTFQPKHTSTQIEKQKKKSAQEVHKGKETVKIKETHPPNIIPETSESSVSSSEQANSSSSLGEVPKIIPDTKKSKNEESRNMKLRSASIEKRVCSKTSSEKQGDKKGSESACREGDTQSKNSSESSELSRTSENPSTDSSASTEMLRPVGKTCLQSIVYVLQTHFGGSLTESFNVLHRNSFNLLTSIMELQSLHPEVEDALYGDEEEEEEDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6M8</accession>
    <name>A0A423U6M8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022477</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000559">
        <property type="protein sequence ID" value="ROT84346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6M8"/>
    <dbReference type="STRING" id="6689.A0A423U6M8"/>
    <dbReference type="OrthoDB" id="9978460at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="17471" checksum="C85DCAE5F9A446F6" modified="2019-05-08" version="1">MALKRIAKDHEELQSHPLENLWACPNEDKDDPYIWQVTMLGPPETPYEGGIFFLDMYFSEDYPWMKPKVQFSTAVYHPNVNSRGEVCLDLLTNNWRPDFTISSVLLGLYSLMADPSPEDFLDLEIANEFVDDRERFNETARDWTKKWAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9W9</accession>
    <name>A0A423U9W9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative nuclease HARBI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_012889</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000262">
        <property type="protein sequence ID" value="ROT85497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9W9"/>
    <dbReference type="OrthoDB" id="2430314at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="137" mass="15481" checksum="09B0B15D2C845652" modified="2019-05-08" version="1">MAAAFDELECLEALEDLDAADQHDIPRRCITDRMNLFHSPHDEEFIKRFRLSKTTALNLLDKLQIQGTRDGRGSPVPPRLQLLITLPWMATGSFQLTIADTFDVSQQLVSNCTAQNSPSHCISATRLCETTIERTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAK4</accession>
    <name>A0A423UAK4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000199">
        <property type="protein sequence ID" value="ROT85741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAK4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="19304" checksum="5EA15FF97F03EBD1" modified="2019-05-08" version="1">MPLLVLSRASRESGVTLIPRPVEGEAEGKGRPAYNLLRLRDSAVGSAATTTMRFLAFVVSPALAVALRRRQVLGLLWRRRSPRRSRRRRWRLRRRIRRIELEDFSEKLHAHHMTNAFSVSKLPLVIACSAPINLECLLKMRFLAFLDLLLAVVCFGHVTLSAKAAGLGVEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAT9</accession>
    <name>A0A423UAT9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyubiquitin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000182">
        <property type="protein sequence ID" value="ROT85795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAT9"/>
    <dbReference type="STRING" id="6689.A0A423UAT9"/>
    <dbReference type="OrthoDB" id="6369678at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="101"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="221" mass="24824" checksum="5B509A5D89F1A103" modified="2019-05-08" version="1">MHSHIQRQAAGIMPLGMNRATMLIYIREKSGKTTPVEVAASDSVEDAREKIEQKGISLTGWNLIYFGKKIRRTQVLSDYGIKHKDTLYLREELQGLGAPGFLLTVAQSSGNVVKLVVSASDRVIDIKQELTREGAPGVDRQRLKAGSVELQNEKSLKDYDITGDAVIWMEDADERKSKEARKRKKVLTDKLKKRLVAVVFVIVAIIMLIWAYVNGKIQINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSV9</accession>
    <name>A0A3R7LSV9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_020115</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003855">
        <property type="protein sequence ID" value="ROT62052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSV9"/>
    <dbReference type="STRING" id="6689.A0A3R7LSV9"/>
    <dbReference type="OrthoDB" id="6378246at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000140">
        <property type="entry name" value="Histone H1.0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF36">
        <property type="entry name" value="HISTONE 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="9">
        <location>
            <begin position="14"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="87"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT62052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="212" mass="22594" checksum="537F1016029FAC54" modified="2019-04-10" version="1">MAERAVKKAGETAGRPKYSQMVAAAIRALKERTGSSRQAILKYVVGVYGIEDEKRAGVQVRLALKKGVAGGSLVQVKGTGASGSFKLAKVEGKAEGKKPAAKKDGTKTKKELSKKPSAKKTTVKKPAAKKTPAKKVSAKKTAVKKPTAKKTTVNKATAKKGVAKKESLKKSTKEKVSTKKTTLKQPSSKKIIKKSATKKTEKKHTNKKLAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUQ3</accession>
    <name>A0A3R7LUQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003175">
        <property type="protein sequence ID" value="ROT64865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUQ3"/>
    <dbReference type="OrthoDB" id="6358748at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="55807" checksum="4FD1E34E9A2B0CB4" modified="2019-04-10" version="1">MSTRDDEREPLLPAPCHAFVRQRSIRLPRNRHPGSLKGWPAHSGTDSVLANDRSPRPTDLTPTDARYSVSGCQFLPPRPAPSRSSEETPRRLSQEALRPTIIGHDSNGRVASMQRQAPSLSPLSDGALRYLETIRQTQQYSQLPRRNSYKDIAPTRRGATPPPSDRFSRQSGSLRGTVSRYSPQGNESSSPRAPPPSAADDLCFRQGPWSPTLPRRCRSATREPESPERSPSFTQTWMQRLGRRSLSPSPRTLTPQGSPVLGRRSLEGSDTTPEGAFKRHGSLPITRKRSLERNWRSSSLRHPRAPTGELKSNRQTLSNSSQRESEACFALLPTPPSDTASPQSPLTSLANTLSNYTGSSSPHRASVSSSHFRDAQDSGSSTGSSTDESPSTSGGVNGCGRSSSFEAGSISSFKSILLRSSGMVLLRSSNQHSPGRLVCSFHVVWSVHSRSYRISSIHTACPSPPSPLPSPWSELRLTRCHYEPEKPPLQPPSYSPLEKEKMDGLRNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUX7</accession>
    <name>A0A3R7LUX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003387">
        <property type="protein sequence ID" value="ROT63735.1"/>
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</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2Z2</accession>
    <name>A0A3R7M2Z2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003027">
        <property type="protein sequence ID" value="ROT65854.1"/>
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        <source>
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    <sequence length="698" mass="78856" checksum="370B1EA1DDD9301F" modified="2019-04-10" version="1">MSDYGFQPTYLLPFLFHSHHSSSLSIIFSLPPSLSPHLSSPYPPSTIYSLYPSPFPFHSHIIFPFLYISSSHFSLVPHLLPYPHYLFTPSHSHIHLPFLYTSSSHSFPHSHTFLPPTLFPYHPFLPIPPLPHILPFSIFPIPIYSPYPLFPFHSHLPFSPSCISPEYHSPSPDFIKIFPIPSFVASSPIISSLFFHNVILSLSFSFSLFSLSPFSCPSPTIHQKTSYSLFRCLIPLSLLSSSQRYFFSLSSFLSFSLSPSLSSCPSPHSSKTSYFLFRAHPPLYLFSLSPKRSSFSLSPLFLSSFSSLSIVHSPDSSNLPISLFRCLIPPLSLLSSSTTFFFLSLSPSFPFKLSIPLIHQKLPIPSFVASSPIIFSLSSTTSSSLSFSFLPFKVVIPLIHQKLPIPSFVASSPHYLFSLPLERSSFSLFLLPSLSSCPSPSFIKNFLFPLSLPQSPIIIFSFSQNVILSLSFSFLPFDAQKAISHSNIDSVPSLLLPSPLFLHLSLLLSLSLSFLTLLLSPFSFSLSFLTPLLFHSFSPSLSFSFLSYFPSLSFSFLSYSPFVSFFLSFSFFLSPFLLSFSLFLSPFSFSPSLSFSFLSYSPYFSFSFISYSPFISFFLSFSFFLFPFLLSLFLFLFHFLLPFYFIISLHLSLFLSFLTPLLFHYFSPSLSFPFLSYSLHFYFSPSLSFSFLSYNPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC15</accession>
    <name>A0A3R7MC15_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
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        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
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            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001468">
        <property type="protein sequence ID" value="ROT77828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC15"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
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            <begin position="78"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="794"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="817"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="841" mass="93515" checksum="B7D4E0E113DBE08F" modified="2019-04-10" version="1">MPYICSWLIRVYFSSLFCSPTSPPLLLIHVYFSSLSSVAFAHPWKWKCVLSLSLFCCLLLLPLLLIQTNIMYFHPWSTFSPLLLIRVYFFLFCSSMSTSPPSFAHPYFSYHSTLPSLLIHVYFSPSFAHPCLLSLLFLLICLSVSSMSTSPPSFAHLMCLLLLLFCSSSTPPLFCSSVSTSPLFAHLSTLLPLLLIHVYFSSLFCSSMSYFSSLFCSSMSTSPPSFAHLLLLPLLLIRVYSSLFCSSMFSSSLFLLIRVYFSSLFSHPCVLLLPHLQVYFSSLFCSSTGSSSPPSFAHPCLLLLPLLLIHVSLITFLPLAHPLIRVYFSSLFLLIHVYFSSPSFAHAHLHVYFSLPLLLIHVYFSSLFCSSMSTSPPSFAHPCLLLLPLLLIHVYFSSLFCSSMSTSPPLLLIHVYFSSFCSSCLSTSLCSSLFCSSMSTSPPSFAHPCLLLLPLLLIHVYPCLLLLPLLLIPVYFSSLFRLSPPIRSKIAIPTCLFAHPCLLSPLFCSSMCTLLLHPCLFSSPLLFSIHVLLLPLLASMSTSPPLLLIWSTSPPDHVYFSSSFAHVSTSLLLLKSVYFSSSFAHPSSPPSFAHPCLLLLPSFAHPLSTSPPLFAHPCLLLLPLLLNPCLLLLPLSLIRVYFSSLFCSSMSTSPPSFAHPCPSPPSFAIHFSSLFCSSVSLLLPLLLIHVYFSSLFCSSMSTSPPSFAHPCLLLLLLLIHVYFSSSLIHVCLPYFAHPIPILLIHVYFSSLFCSSMCTSPPSFAHPCVLLLPLLLIHVYFSLFCSHTMFYSSSLFAHPCLLLPLLLIRVYFSFSLLLHFRVFLLCFFISPSSTSIRIVPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC25</accession>
    <name>A0A3R7MC25_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001346">
        <property type="protein sequence ID" value="ROT78686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC25"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="551" mass="61654" checksum="62D613585F5462E5" modified="2019-04-10" version="1">MEDKHQVVKNDNEPGPLVPRRCTLRLDPRVLVSVASAVGPRVGSFRNPSGGRQHEIRRFLLVLLHASLVLVLAAATLAGGGGAALASGSRAKKEVANNGPTPSYRLFIKPMRRSSSPQAARERTPPPPSPPHDPVQYDYTEATNRYLYKYDTTASRARANSTNVRHAGQGGSAPFGRREQVGGGDDQEEQYFRVGQESARQSPNPRSFDEAQRHFDSILGDSDDSVSTSLGLSPAEQRLTHANRSVQWNGRRSMDGDDYSLEEEEVLEGVSMDDPEALLPDPTGPALSLLEKRLHHSSIRHRKSRRNFVRTRKSPKMHSRAHNGEYPDQSHRGPRRTETRGLRDRVGVRAAVPQHERPGIRGVHISSTATSLPWSSGAPNLENKFRATGDIPTEDTNVVDEEDDAQETEREGKTTHVDIVTKFLRIVESQHLLGENCTKGTDFNLGEGVVDRYAQERFRLEGEIAVNRANLYTRLWKYSPEQVLASQYLLHAEVLTMVELDEDIFAAGNCYDKYEYEDYLLFCPFAYRLSRGQHPRQDLAVEYKVLLSNTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD24</accession>
    <name>A0A3R7MD24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002057">
        <property type="protein sequence ID" value="ROT73171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MD24"/>
    <dbReference type="OrthoDB" id="6378171at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16021">
        <property type="entry name" value="ALP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004245">
        <property type="entry name" value="DUF229"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10974:SF1">
        <property type="entry name" value="FI08016P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02995">
        <property type="entry name" value="DUF229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="935"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1508"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="756"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="935"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1564" mass="168995" checksum="A10348550314F592" modified="2019-04-10" version="1">MLHSGCETVNPHLRAHTRLWRTLGAWTTSCSAGARHGPQRHPHPLPAPRRLLVARVLPAAAQHVLPVGQDVQDNTDFESSFDPDAFFRQHRHLLAESDHSTELEKSLYDRRKGIAGTYSTLESKSPSGFTSAHDTHLYAGMTTPYDELTYEETLFEVKVDRLQPRAPSLRGAKAESSIPPTSEEEAALQVFLKNRQLKAQAEAAKHEPSKTKSEVEALKKAKEERNYSKRNTTSFGAAAPAWRRRRAPTAPAPSPAARASASAAAHHHHRLDARDGRQPGRPPLGVAHQVVHRGAHQGVERQIRQEVAEEASLVTRRAPQPQDALPRHDARAAAAADAEDSSSKEYILREIAAVLAAKGYLPGAQAAPGDGAPRRRTPPFQKGASVRGRQPAPARHRAAGVQQLSRVQRYKSVSPRSTPPRRAQGGRPLQRQHLRSHKEPKREPAAQDSSLPKTSGSLASSGDAGDAKRRKRRSTGSRSSLTSLLRAPETSSSDTELDNSFRSRRPGGSGRKGGAVGVTARAASLEGGAGHGTYALPSIVVSNQAIPVARVGGASRRAPGFRPRLAPPAGLDGRQEKQLEAIYSALSTAPAAGAATKSASGIRAPAAVKARRASRRPDGRGASAVARSSSGAAPAEEGRPAAAFVGQVAHEARGRDQRGQDAPGRVLPAGDSGRVAGRGQQGEAGRPAHAPGGPRAHPVVPGAGGGQPRVPEPRREHAHVPDRQRNGDVAGDARGGRPAPERGAREQAPPSEGTLASHAPAGSAQAAEATAGITDSGASATEAAKASPEQFDEGGASARPSRTLERRSSLASRPGSPQHQSPARQSLGQASATSQPHEDRSQADYFVMDHVTGNGGGGGEGRRQRKRVSDAGGAGRRRPVSMKNCGWRSRVSHSSLSRLNRYRCCYSVCMGEAVARGVNHAPEYIMDIKVPSLNSSSAASSTAPSTPGNYGHKSTSDKNGALTSANGTTLYYHPQALHDHLDYFLKRPSLSTTSYVSVETENERAIREHKLINSNVYFDFVTNTSSDLGGDGGPDGSDVRCCYRAIYRVEQKPEVYNAAADGRWRYSPWCAPLEGERTAIREDAVLVYCNMSHVVVYKNEDPEDTERLSVIIFGTDSASRLNMRRHLPKTYQYLTEELGAVDLGGFNKVGDNTFPNLVPVMIGLSSAELSKHKCVPTKEKFDDCPWDSPWMGIFNYMHNGFVTPPTDYGRAFFLASEKEIGREKHGNSNFCQGPKQSLQVVHDYSLEIARTFRSRPSFSLFWSASVSHDNLNMLRHADQPHLEYLKKLQEMGALNRTALFFLSDHGMRWGTIRSTYVGMLEERLPYVLVYLPPWFRERHPYSPPYLTSLPHAHTHRSLPQYTPITLPSPHPLPPSPLPSSLCPFPPFFFFSLLCFSLPPLPSPPNPPFCPHPFHHYPPFSSSPPSSLLSSPVILPSPCPFPSLLTLSPPSSPSSPLYLPPLPSPYPFPPSSPLPFLLPHYPSPSSLSSPPSPPSLLLPHPLLPHYPLPLPPPSPPSPSSSPPPFPSLLSPLPPPLPYPPPHNPPFSPAPLPPPHKYVLTRAFPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGC6</accession>
    <name>A0A3R7MGC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001741">
        <property type="protein sequence ID" value="ROT75711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGC6"/>
    <dbReference type="OrthoDB" id="6348647at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="21196" checksum="B637475E4DDA7EBB" modified="2019-04-10" version="1" fragment="single">TKCATCEDSYKRAVDDNTFEIRELDLPDGMCTNDTAYLISTPDRCCSNSCQCKYVHGSECRHNYLYDNNLIRCDYFLPDSCPNQHCCGCCLNCNVRICSDCLRKEGATCRRTCQWNEYPISVQCHSPYCQCCRKCEMESSCQASGGRCVGHPSFCRSGYYLSKRGCNGDCYCCYPPVQHTGYIDKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGX1</accession>
    <name>A0A3R7MGX1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Glucosylceramidase</fullName>
            <ecNumber evidence="3 6">3.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_005258</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a beta-D-glucosyl-(1&lt;-&gt;1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose</text>
            <dbReference type="Rhea" id="RHEA:13269"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:22801"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="EC" id="3.2.1.45"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:13270"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.45" evidence="3 6"/>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGX1"/>
    <dbReference type="STRING" id="6689.A0A3R7MGX1"/>
    <dbReference type="OrthoDB" id="2160638at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006680">
        <property type="term" value="P:glucosylceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069:SF23">
        <property type="entry name" value="LYSOSOMAL ACID GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0746">Sphingolipid metabolism</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 30 TIM-barrel" evidence="8">
        <location>
            <begin position="136"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 30 beta sandwich" evidence="9">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="27759" checksum="47805550B79B7679" modified="2019-04-10" version="1">MDNLCQAGAATQWFPYLLPSPPVNGFRSGDRDASDRSRSDARAQPPLQKMNCASTSIEAHLIFRSGGCARASGARFVTCISVATPESTTPSLNWAVIICLGPVNVHQAPGWSNLCVEEFSVVPVLQTQVHGRGSFPFAVDVALGKWERLESYARYIIEDMNHWVTGWMDWNLALDMQGGPNWAENFVDAPIIVNKEADEFYKNPMFYAMGHFSKFVKEGATKLGLASENQKKLDATAFRNPDGSTAVVILNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNC3</accession>
    <name>A0A3R7MNC3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AP-3 complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_015918</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002992">
        <property type="protein sequence ID" value="ROT66085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNC3"/>
    <dbReference type="STRING" id="6689.A0A3R7MNC3"/>
    <dbReference type="OrthoDB" id="302453at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026740">
        <property type="entry name" value="AP3_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056314">
        <property type="entry name" value="AP3B1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029390">
        <property type="entry name" value="AP3B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14796">
        <property type="entry name" value="AP3B1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24080">
        <property type="entry name" value="AP3B1_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037096">
        <property type="entry name" value="AP3_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01355">
        <property type="entry name" value="AP3B1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP-3 complex subunit beta C-terminal" evidence="13">
        <location>
            <begin position="738"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="634"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="666"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR037096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT66085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1023" mass="113333" checksum="77EA2FBF639B084C" modified="2019-04-10" version="1">MYSQPLNPDSYMAQVRGTTISENNHIQTIEFVVPIQVSQDAPRHEDLKQMLDSNKDGLKLEAMKRIIGMVAKGRDASDLFPAVVKNVVSANLEVKKLVYVYLVRYAEEQQDLALLSISTFQRALKDPNQLIRACALRVLSSIRVPVIVPIMMLAIKDAVSDMSPYVRKTAAHAIPKLYNLDPEQKEELIQVIEKLLSDKTTLVVGSAVMAFEEVCPERIDLIHKNYRKLCNLLVDVEEWGQVIIINMLTRYARTQFIDPNAGEGLEEKEKPFYEDEQEEPEDADTLSKRPKTMDPDHRLLLRNTKPLLQSRNAAVVLAVAQLYQHIAPRAEVSQVARALVRLLRSHREVQAVVLTNIASMSTRRKGMFEPYLKSFFVRSSDPTHIKALKLEVLTNLATDANISVILREFQTYIGSSDKEFVAATIQAIGRCASNIREVTDTCLSGLVSLLSNRDESVVGESVVVIRKLLQSETVGHKDIISHMARLVDNIKIPMARASILWLLGEYCDKVPKIAPDVLRKMAKTFITEEDIVKLQILTLATKLYLTNPKQTRLLCQYVYNLAKYDTNYDIRDRARLTRALVFPSQGHEDNKLAKHAKKIFLATKPPPVQQSSFKDRDQFQLSTLSHFINARASGYQDLPPFPDDAPDPSVRNVEMPAPVTPVFKSAHQKKKPQKRTRGKAKRKSGGGGRKREASESSESESSSDEESENSESSDEDTKKKKSKEKMSNKSKATQGGGNRTNLDLLLDLDDIPPAMDTPLLTPSLGGLLTPTPTAQPAQPLPPGASIQPASAKFVPTTTHELLNRFTGVGLSVGARFTRSPHLYSPKMTSVELTFTNNGTEEIRDISIGRKKLAPGMSLHEFAGIAVLNADTTLYGTLGVDFNDTTQPAVFDLIAGGRTFSISVTAPIGELMTPLAMSEADFNLNQGKLRGMNELSGTAKLPSEQKNIKALVDHVYEIANLLQVQSSSDNVLKFGGQTVSGKVLVLLSLTVPEETAECSITINCEKMVVSSMLLKELQSALTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPT7</accession>
    <name>A0A3R7MPT7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002869">
        <property type="protein sequence ID" value="ROT66987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPT7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="354"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="46885" checksum="1805E6CB0823A076" modified="2019-04-10" version="1" fragment="single">MRVGGGLLPPLSFLPLFLPPSPSLLPPRLVLLSLSPFPPNPSSPFTFLLSTSPFPSSYLFPLFRLPLSSLLSTFLLPPSLSSPSLPFPLPSSSPFPTSSPSPSPPSPLPHPFLPLPPLPVPPFPSPPLSHPLPPPLRLPLSPIPSSSSPFPLFPSSFLLPSLQPSFPLLFLLSPSSLSLPLRIQPLSSSLLPPSSLLFFSLPLRLQSLSSSFPFSSLPPFLLPLFLSSSSFPLSSLLPSPPASNPSLLHFFSFHLPSFPSPIPLFSFPPLPLSPPLPPSLSSSPLPASPFPLFSLPLRLQSLSSLFPLFPLSHPLLPPSPFPLLSLSPQSPPSSFPPLPLFPSSPSPNPPPSSFPSSPSLPSSPSLPSSPSPQSPSLPLSPPLPSLPSSPSPQSPSPSPPIPFLSLSQSPSPSLPSSLSPLLVTFVCAIDQHSLFYTNWRLLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQL8</accession>
    <name>A0A3R7MQL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Proton-coupled folate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_014469</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002808">
        <property type="protein sequence ID" value="ROT67472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQL8"/>
    <dbReference type="OrthoDB" id="419734at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF37">
        <property type="entry name" value="GH08173P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT67472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="41440" checksum="B8F574076F0C5888" modified="2019-04-10" version="1">MYRSIFETSIKVIFVLYLGSWSDRTGRKVPLVISLLGLLGEAAVFLANALSPSWGVSMALLSSVPYSLSGGTHALLMLAFAHLADTSGRRERTVRMGLLDAAYYLGSPVGMALVSPLLNAGGYTAAFGTAILIYCVSAAYVLLRIRQTGRQRELQNGPESACDLSHLSEAVAVTCRPRHQRATTHILLLILAMLCDSMPVWGEGNVKYLFTQRALDWNHNQYSHWGTFSSLLSVAVLVVVVPVLSGVLGVPDGWMGVIGAVSRTAGSLCYTFVTSPSLAWLMWMGAVISSAKNLAPVSIRSLLSKLAGAQDVGKVYAVMATAESILPFAAAPMYNAVYTATNETRPATYNLLSAAFYSCLFALILGVTLSLGKIASRTSSGERQPANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSZ1</accession>
    <name>A0A3R7MSZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Myosin Va</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021217</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000441">
        <property type="protein sequence ID" value="ROT85130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSZ1"/>
    <dbReference type="STRING" id="6689.A0A3R7MSZ1"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009888">
        <property type="term" value="P:tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004009">
        <property type="entry name" value="SH3_Myosin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51844">
        <property type="entry name" value="SH3_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 7" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin N-terminal SH3-like" evidence="9">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="8">
        <location>
            <begin position="66"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="160"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="460" mass="51868" checksum="2A64A5AB54BF1B06" modified="2019-04-10" version="1">MSVRELYVKGARVWIPDPDQVWRCAELTKDYKNNIVAVVYDDAQTEDLVVKNDEELPPLRNPDILIGENDLTSLSYLHEPAVLYNLQVRFCNQNAIYTYCGIVLVAINPYDEMPIYGPDTISAYRGHSMGDLDPHIFAVAEEAFTQMERENKDQSIIVSGESGAGKTVSAKYAMRYFATISGSDSETQIEKKILASNPIMEAIGNAKTTRNDNSSRFGKYIELDFTPSYSIMGANMRTYLLEKSRVVFQAPDERNYHIFYQLCSAAEQGKLPHLKLRKPMRFHYLNQGLQEGPMVASKPRKGHQDNFHYLKQGSSPHIDGVDDAEDFIETCKAFSLLGINEGMQEQIFRILAGILHLGNVVLEEGNGDSSAISTGDKSLKTVSELLGIDLEDIRKWLCNRKIVSGREVFTKPMTLTEAVFSRDALSKHIYAKLFDWIVTQINKCFAAKAKPYRFIGVLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N2G1</accession>
    <name>A0A3R7N2G1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative serine proteinase stubble isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005989</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N2G1"/>
    <dbReference type="OrthoDB" id="93664at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="775"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1060"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="153"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="569"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="615"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="682"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1154" mass="119849" checksum="BA04CE795EAB4E4A" modified="2019-04-10" version="1" fragment="single">ASQSSADPAQVTLRFQRPSTKQDSAMTRLKWSSLWAGCLLAVVGLTAAHPFLYMRGTRHGYGRNIRPLPCVSKGGETGVCMFAWDCMKANGTHLGTCIDRFYFGSCCKMAHARPPPGLNEIPSGGGSGGTKPMGVDASGQPSAENDGSSESQESPGDSDAASGSASTSGTGSTSGEAEGPALAAGTGSTAGAEGVGPTGGVETPASTGEVDGSTSTGTGAGSTEESGDASVSGAEGPASTTGTGEDGSTSGVESPASTTGFQDGENAGEVDTPSSTTGTGAGPASGSESSTSTAGEGADSTSGPEAPASASGTEDSGSTSGVDSPASTDAEGTGSTGSSDGQGFDATPTTEVSVAVDPAPSQPDLPAGTQDSVDEDTTVAPGSGASSPDVTESQATSPSMGTAAPVSPPATESPTASEATIVIETEKPQTMTTTMLQAGSDTERPPTTEEAGAATVSITVSGDAEDGGEGTQKPTEVPALAAATLPPITSEEPVIIPVTTFAEVSTTKPEEPVSQPFFPVFPAAASEKPEEVTTLVPPPESGTEKPDEQVTLVFPSGPVATGKPSTLAPTTVDTTEPDTTTSSSEEEEEMSEPTTPEPEEGDDSSEMPEIDVEATSEATAPETTSKPAAETTVMPATAEATEKPEEPAVATMKPEEPAVATERPEEPVVTTMNPEEPAMATEKPEEPAMATEKPEEPSVATEKPEEPAVMTEKPEEPVVSTEKPEEPVETTVASGEGSVTTLAPTVTAEQELLERLNNSKAKDICGKPVYPTRRIVGGSEATFGEWPWQVSLRQWRQVTFLHKCGAALVNENWAITAAHCVENVQPEQLLLRLGEFDLERSDEPYAFAERKVQIIATHPQFDARTFEYDLALLRFYEPVNYQPNIIPICIPEDDYDFIGDTGFVTGWGRLYEDGPLPSVMQKVPVPVITNEECEAMYRVAGYVEHIPHIFICAGYEAGASSGNFLLPQEGSHWKRCLDRLGHSRVCSAFFSLQDGPLHARMQEVEVPVISNDECARMFLRSGGIVALPRIMMCAGYAEGQKDACEVLEKALHPLLPICTGRPPAPTSHSPPSDEPPAPPPNQTTPYHHPFPSDIPQAALLPQGDSGGPLVIQRDGVWNLAGVISWGIGCALPNQPGVYTRISEFREWIQKIVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N411</accession>
    <name>A0A3R7N411_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_004691</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001617">
        <property type="protein sequence ID" value="ROT76713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N411"/>
    <dbReference type="STRING" id="6689.A0A3R7N411"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040214">
        <property type="entry name" value="BRD10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056522">
        <property type="entry name" value="KIAA2026_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31095">
        <property type="entry name" value="RIKEN CDNA 9930021J03 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31095:SF3">
        <property type="entry name" value="RIKEN CDNA 9930021J03 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23450">
        <property type="entry name" value="KIAA2026_hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="230"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="641"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="739"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="936" mass="106331" checksum="FD43545A4F780F83" modified="2019-04-10" version="1">MGDTDPGRGCPPALLSDVESTGNNVNNNNNPSAGRGVAPHAEQNGRGELERKQPVIEDVGDAASRTSEESAESLSSMNSHLAWREGPKPQSKAQPSYRMVADHSRHTNIRKESSLLYSRRDEEKSSFGLYSGMSDIISGSPQSAAPSPTPSSCSSTPSLTPNKSTVASGGLPRPNSTFGSSLVYKGSGGGLLVHHPVTPKKRVLTKTKTDHLSEELNLGYRILMELMSDYQKGSNAPFMEPIELDTDKNKDYLEVIKKPLWLKKIKEQLLDGQYKTITELIGDLRLMLENAYRYFGPVHSISKKGLRLEHMMEQKIALLPKEIREQCSLEKTSGQPPEDITQKHRNKRAKISVNGDNFFSYVMHRVRGCRVQREKELKRRKMEAMRQAKRDRELEVIQWEKDLLKEPLHSQMRAMWELPQIGHFIYLTLKTLNIYEVPQYELERMLLMPRASRTLAMLLTSLLSSPQQRQKLNEKPYMPYKVWARKLAHKTLLWYRCFSRENQNSQKVFDQMGIEPQFWNICGPTNPFERQLFHEMTYHQRVWLLKSLCDFLLHNHKTVQEVIAEHTEADQREYHLGRDRDGNEYLHFPQFCGQDLRIYRRAQVPSPEIKVEEEEHKEGSILPIEKVREFKKMMKRIRSKYEEEAEWEGSRGKKRKRKRGRNREVDPEEEVSFHNRSRPGNLRQRPRARYKDQYEDLGLSSDDEPPRPKFKGRRARASAAAEETGEEGAANSPAPPQQEGLTRAQQKNPRTRRGGKKKPTCEICGKTFQNIAALKGHRAVHTKEKVHAQLATPPMAPRLGSDDDHDVLARRTGDIVAEGPRAVAHVVPLVVKGVGTVSCCASRREEPRSGSGEEVYGRLESWADEGEVPRTPVQLDPDLWRVIQQMDGSLKAHSGSSIADACCGVMVLACNTCGHRNQMIYDFGDSSGAHSKEGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N504</accession>
    <name>A0A3R7N504_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_003923</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001526">
        <property type="protein sequence ID" value="ROT77422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N504"/>
    <dbReference type="STRING" id="6689.A0A3R7N504"/>
    <dbReference type="OrthoDB" id="6367814at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="215" mass="23122" checksum="E02E2E59563292C4" modified="2019-04-10" version="1" fragment="single">IKQLARPQNYRPVLLLAAVFILRELGGQHVVFSYTVYLFQKAGVGLDAFVCTILVGVVRLVFTVVSAAVVDRVGRRPLLIATSFVCGAAEVVGAVFLLVDVPGSSWVPLAAVLVFVSSYGLGIGPIPWTLMGELIPTPVRNIGSSLCNLNFSLFTFVISFVFPYLMEIGLGYALLVFASANAILTLLLWAFLPETRGKSLSDLENAFQSSPGHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7I0</accession>
    <name>A0A3R7N7I0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thrombospondin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001972</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001260">
        <property type="protein sequence ID" value="ROT79305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7I0"/>
    <dbReference type="STRING" id="6689.A0A3R7N7I0"/>
    <dbReference type="OrthoDB" id="14563at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008859">
        <property type="entry name" value="Thrombospondin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05735">
        <property type="entry name" value="TSP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51236">
        <property type="entry name" value="TSP_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSP C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="229" mass="25871" checksum="2A23333028046091" modified="2019-04-10" version="1">MNDVDFEGTFFIEDTSDDDFVGFVFGYQSNAKFYVVAWKKGPQDWFNKAERGITLKLVDSATGPGPALRDALWLTGTTPNQATLLWHDGSIGWSPNVAYRWQLHHRPDIGTIRFYLYRGNNEVMDSGNIYDDSLKGGRLGLYCFSQEEIIWSNVKYTCEDGVPQEMFDDLPQNLKDQVLNTTGISTRSLFTIGGMGALDRSLFQEPEGENGNRASNGKPRMNWVQKPCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N9E1</accession>
    <name>A0A3R7N9E1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001067">
        <property type="protein sequence ID" value="ROT80800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N9E1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="504" mass="56874" checksum="48D7FB41D49270FB" modified="2019-04-10" version="1">MIILTPLLVSLPHTHSRFHTHKKNSTLTISRVSPSHSLPLLHSPSHSLTLYTPTFTLSLTLTHASTLTKKTVPHYITGLSLTLTHALTLPLLHSPSHSLTLSHSQKKTTLTISSHSLTTLPHTHSRLYTQFYTLPHTHSRFHTQKNPTLTISRVSPSHSLTHSHFYTLPHTHSRFHSQKNPDPHYITCLSLTLTHAFTLPLLHSPSHSLTLHTHKKNPDPHYITCLSLNSLPLLSLSPSHSLFYTTKKTRPHYITGLSLTLTHAHYTLPHTHSRFTLPLLHSPSHSLTLSHSQKKPDPHYITCLSLTLTHAYTPSFTLSLTLTHALTLPLLHSPSHSLTLSHSQKKPRPSLYHVSLPHTHSHFYTLPHTHSRFHTHKKNDPHYITCLSLTLPHALTLPLLHSPSHSLTLSHSHFYTLPHTHSRFHTHKKNPTLTISWVSPTHSLTLLHSHFYTLPHTPSRSHTPTFTLSLTLPHALTLPLLHSPSHSLTLSHSQKKPDPHYITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NFI6</accession>
    <name>A0A3R7NFI6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative histone-lysine N-methyltransferase PRDM7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_005488</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000171">
        <property type="protein sequence ID" value="ROT85839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NFI6"/>
    <dbReference type="STRING" id="6689.A0A3R7NFI6"/>
    <dbReference type="OrthoDB" id="10572323at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF66">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21549">
        <property type="entry name" value="PRDM2_PR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="313"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="63"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT85839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="585" mass="65247" checksum="7F76B93DE20BB7F2" modified="2019-04-10" version="1">MPFTSSISVEKSDGVLAFAGAPRGRRSCAKGNVESKPREGKGNTMISKAFSIHSLKQLRRTFRTGPQAPGVLRQQRKRRNGLVAPTARPPRVPDDEGNDEWTPEKERSSRHASKSGSVGGGRNGGHKRKAEWSAPAWTGRRENYDDAPLSVDQVDIIPLWTPAKLVAGAKGAVKIIPTTADRSNGDSAAEYVKPEDKGVFSIPMSQLATDTETVTMKELPAETEPPGVRSDEEGRGNSCFSEEKSKTRYPRRCSRRKVFYEENITKDDDFMYCAGCDEEKEGECPYHPLFLILDNPVVRDGSEKDRARLTTPWPLTVYDSKVKGAGKGVWTNAHLPANLVFGPYEGRVLSGPPEAGKESGYGWKIRGAGTRNRCIDAVDIAVSNWMRYVNCSRTRAETNLSAFQYKGQVYYRTDSAIRRSRELMCWYGADYGKDLGLSREPSKWKPAKKDVKDRQCEWCGLVYSSKDYLTLHLKVSRKSVRTYTPPICSTRGSSSNSGSTKQCLREEAPQFPEKAPHESLLFCPLSNFQPLFCLYFDHPPRTVSLNNQSALVLFYLFGVSLNDYVNITPILHLCARPITNSVNMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NFK3</accession>
    <name>A0A3R7NFK3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nuclear receptor corepressor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N-CoR nuclear receptor corepressors family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000162">
        <property type="protein sequence ID" value="ROT85865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7NFK3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000026">
        <property type="entry name" value="Nuclear receptor corepressor 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051571">
        <property type="entry name" value="N-CoR_corepressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031557">
        <property type="entry name" value="N-CoR_GPS2_interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992">
        <property type="entry name" value="NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13992:SF39">
        <property type="entry name" value="SMRTER, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15784">
        <property type="entry name" value="GPS2_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="6">
        <location>
            <begin position="444"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="795"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="6">
        <location>
            <begin position="798"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="802"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="148"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="525"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="860"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1124"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1314"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1536"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1663"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1779"/>
            <end position="2160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="567"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="603"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="624"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="877"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="929"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="963"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="985"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1148"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1321"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1358"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1443"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1663"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1827"/>
            <end position="1845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1938"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1961"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2003"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="2078"/>
            <end position="2092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2101"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2131"/>
            <end position="2143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2160" mass="237685" checksum="614AE9ADB224DEA1" modified="2019-04-10" version="1">MKRLRLRSFLAVLAPRAGRDRCLHDGSPYKTPISPPMASRAGAGGYPAYPPSGDTHGRYIQPPPIQQQPPFVAYPRDQSHYVRNTDRPMMLPHGPRRPTIMGNYGPYTHSHPRTDMMSIVPGNPLAISTTIDSSKRMKLSQQMKPLVVDTSENNHSSRESTYTPQVEAISPTLPSDPRDESPLRTTKDDLLKRIEKVDRDIAKAESSIAKLRKKEGELEAAAQKGEGGKTEEEDTKEPKHQSLAQIIYADNRKKAEESHTILDKLMPPTEEPSVLPLYHQPTDTEVYMENKRQYAGFKRRLMEYFKKRHADKNSRDAHLTQTYSKLMTEWLKKVEKVENSKKHKEKVAKNRELFEKVFPELRKQREEKERFSRVGARVKSDAEMEEIMDGLQEQENEDKKMRAYAVIPPILLEEKKRQHRYNNRNGLIEEPIAEYKDHKNINIWTEQEKEIFRDKYLQHPKNFVAIGSYLERKSVSDCIQYYYSTKKKENYKVLVKRRIRRPRKPNNPPVVEVVGVNVTGVTTRGSVAALRGQQTNRQGPPTMTGSLNNNSNSNQGSSGESEQTQNYPVNNTPGGEVSANSLPATTENSPVPSPNHAATVGVSQGNESSNNSGTNTAPAISNQEVREKDKENLSNSDKPREKTARRERLLKEDDKTKDTQDSSDDDNAAEHGKGGPHECVVCNAQLEHFGQSRPVAAGQASRYGLSEAHLPPNPRVCTSCKCRATRVRVRQCPIPTCPTPKWRGKRLRPLPSRWADLPPQVKEPIIKEFQIPSDCTKCCSACHNRITRKLGPDAEEPVDPSRWSDEDLDALRSALREVGCHWSKVAERVPSKTEGQCKSFYFNFKKKYKFDEIVAEYRKARGKGDGPPTVTDEEESGSSTSSCDEGPLPALPTGPDSDTTSAPSPGPAHQNNIDEKREAAGPGEGLMKEPPPPVAPQPPSVREDYDSSATASADEGQSGAGRDSPERLHTPGRYNDPRDGLPPSDASTFDTQDTQCEGLDLSVRKRDRSPPPKQRPRAPRPPDHFHHPPHRTSRTSHQPPPPRPPRRCPDLPLTVRGGAELTITNKEPPPQAHSNSAHEPWAYADPRNKSPSAFISDARALPHPASSIMTNVAPSGAQPLVYATHVRPQHTQSSKSKPSMAPPPPLTVRSQHSAQQPVSVASRISVKAEKPLHVGSITHGTPVNPPPIVSVPITQPARFDMMPKSGMGKEGGSITQGTPMHHEQKRISGNLYKDVVGVVYEPRPGSGVEIIPRPSLNPQYEREHSYRGRGRPISLAPPTTTYPYTNYPYATRPPYSESQISSRQIIANDYITSQQMHGRRAVSEKEALVSPRGRDHSPQSDPRDHRTLPGTTSVSRIMEARPVDPRTIDIRTVDHRPPELRGIDHRMAHSMDPRIYYPGGPPGGPPGHGSYQPPAQPSAPVYHPVDRVSRPPPSPASARDATPTPPTSDPAPSPHDFRSPGVSTPTPPPRVGVIQRRPTGSKLTPHAVPPPKSISPQLEPNRYSPRHPSGSDNFHAFVDIAVAQRSNVGYAMPEMRREARPPSHHENRQLEGFEKHFTDSVRNVRTIDRDKHDGRVPPPQGERGYYEAVDRHRIAKNPDGKANLEAEVARDMAACFRKDDPKNAQAQKHRNPDETMTAANLIDRIITQQINHNSGDCGTGGGGGGGGGGCSGGSSCGTSGAGGERGGSAGGGGGDQRTYRRDGEVALQVVELDKRVRSPAAPMNKEEVVMVEDGPEPRPPNPVNHKEGLGASLHAASHHPGSQPKSMQAHLDQMIHRELSSGDGRKMGGPHMPYSRSFEILRTEGRPLVGSGGPPAVTVSQVGYDPWKMRGHDKESGKERLESRSPHRPPPTTAPPSSHHLSAQHLAPDERKIIRIAQSVSPRPDHKMRTPPAAPAGSFPVEPISPPTSSAQPPADLNHTDPNPPWQRKRPYPPPPQSKEEVFEYVRCKIAQVMRTPETQESDKQRVHDDRRPRSGTPVSQHQQQQPPPPPPQQSAPQQNAHYDMEDAAKKRARLEAAERPPSRPRSTGGDMVRDRREEAVAAAAAAREEAANSPQSDEMVIDESPRDAHPPSKTGADMGGNKPGGPKGGDCGGDRPSYPPANTVSGSQYPYTYTGFRGHGGPPGAPPPATTASTTSSNANSGRHAQGYEPSVEPVSDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NP66</accession>
    <name>A0A3R7NP66_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003501">
        <property type="protein sequence ID" value="ROT63054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NP66"/>
    <dbReference type="STRING" id="6689.A0A3R7NP66"/>
    <dbReference type="OrthoDB" id="5582218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045817">
        <property type="entry name" value="OPA1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19434">
        <property type="entry name" value="OPA1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PXA" evidence="2">
        <location>
            <begin position="74"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="591" mass="66501" checksum="FA0851DC8D78E213" modified="2019-04-10" version="1">MSRWLRGYTTWTIFNNFLREGPTSYPLLAKCFSIVERVVEKGHGISPDVPEKGIQSSPVHTLRGAGVLQITGSGELVIQELEITAASLHSILVHPWYSHVSPDNHFSYQIKDILEDILISMCQRIKQSGNVTAVASGIIQVYIQHYRQYQRALRKISKKHKDSEPLSSAGVQELQAKYKPLHPALKSPETLRTYYRKLAQILLQHYLPVEMIRCNLILVSLRDLFAQNVLQAFVDLLCDTQWLNTVLAEILSEVSDGATGVGGAGGLGGQSTGQEASSEVSDVSKILQQASNSEKLQAHTSLLEAIEEETLSELQQLDPAVALQSDAQQSQEGSSPKSEDDSEAKSAESEKFENAEALVQYVRSSSLEKESKEDEDYRTVSSALGTLLSTTAGPLLPDNSAMQYQPLVTKMWESPVDDKCFVDMSSLRRKKNPFSRNVVEEWKNNFPRTRELDRDELFEKARGEILDEVVNLSQVSPKQWEDALSKKMWDKMVTHIFENIYLPAAQTENSGTFNTTADIKLKQWADGMLPKKCVEVGWETLEDEFRKFMERAKNSKDHDDIFDSLKACVVDEAMRRHEWEDKAADVLRVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRK1</accession>
    <name>A0A3R7NRK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRK1"/>
    <dbReference type="STRING" id="6689.A0A3R7NRK1"/>
    <dbReference type="OrthoDB" id="265955at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026319">
        <property type="entry name" value="ZC2HC1A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049899">
        <property type="entry name" value="Znf_C2HC_C3H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555">
        <property type="entry name" value="C2H2 ZINC FINGER CGI-62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555:SF66">
        <property type="entry name" value="ZINC FINGER PROTEIN 474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13913">
        <property type="entry name" value="zf-C2HC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52027">
        <property type="entry name" value="ZF_C2HC_C3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2HC/C3H-type" evidence="7">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="420"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="50689" checksum="05B5B787E3DFA639" modified="2019-04-10" version="1">MEAGERETTTQPSASRTGASRTRTHARGVERVRVEDGPVLFSLLSLFSFFNLSILDLSTLNSLSLVLSSFTLLLSLSQSLSLSTKAPASPLEASAGERRPPADQEDEEDILVSLFAFSLSSSSFLPSPSPSLVPTLPPHLPSSPTHLLLPSPSPSSPSSPSFLPPQFPPSSQPILLHFPTSYSSPFLPLPSPTSSSSPPSVNRPDTSTNLNASLSVSKPTIVCYICGREFGSSSIKIHEPQCLKKWRIQNENLPDDLKRPEPKKPEVVYDEEGKVDKEAMAEAAWKTHLETLVACKCGRTFFPDRLIVHQKACLKEAFRSYLSTTSRVSELPVSKFPGFEAPCLEVPGPGVSELPVSNFPSPFLSNFPGPSSRASRVSSSLELFLSKLVRLALSCPSGDSDSGLAPWTWMCRRTTRLKRSAFPVTSPPPPSLPLPHTSTRIHQLRRTSQPSEIQTPTLLIRDNHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P886</accession>
    <name>A0A3R7P886_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_018455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003402">
        <property type="protein sequence ID" value="ROT63651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P886"/>
    <dbReference type="STRING" id="6689.A0A3R7P886"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="8">
        <location>
            <begin position="117"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase RNase H-like" evidence="9">
        <location>
            <begin position="326"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="201"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="472"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="511" mass="56380" checksum="C027A115521EE300" modified="2019-04-10" version="1">MPLHPPFPHRHGGRAHWKLPRDAINVYGERLETSFSDRRPQPTIPMDLPPGRSTGLPNHGTRSATTFETHGPPATLSLPSARPRQMSQRQGGVRPHEAVRDHTPFQQPMGGPLHLVKKDGDWRPCGDCRHLNTVTAPDRYPLPHLHSSHELSGCTVFSRIDLVRAYHQIPIAEEDIPKTAVITPFALFEFLRMPSVSATPLRPSCVHERRDSRALRGSSYKSTTSPSSPAPQRQTTPVISAPLFGRLQEAGVVINPGKCLWRSFALFLGHTVTPQGITPAQEKGQQKHQNQVDAPTNEAFEACKEALASNHPAEPPLPEAPLSIATLSPRQSRYSAFGKELLAAYSAVRHFQPYVEAKEFHILTDHKPLTFALHSRTAANVLTRSATWTTSHSSRRTSVTFVAADNEAADALSRVTIAAATHADDAVNYHLVSSEQRQDASMIPLIEGQTSLALRESRSKLTRRPSLRCLPRLPRPYIPLPSASDSSTHTTSIEASGHPTSHPRQSRLAWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9V9</accession>
    <name>A0A3R7P9V9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001218">
        <property type="protein sequence ID" value="ROT79621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9V9"/>
    <dbReference type="OrthoDB" id="201213at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02429">
        <property type="entry name" value="PTH2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042237">
        <property type="entry name" value="PTRHD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12934" checksum="4DAC153614CA387C" modified="2019-04-10" version="1" fragment="single">MLQKTMSGAALGLVQYVVVRSDLMTNLAWPVGAVIAQACHASTAVAHLYREDQNMQRYLADLDNMHKVVLGIESETKIRNLSEKLQEAVIDHKLWIEQPEDTPTCLVTKPYPKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCE4</accession>
    <name>A0A3R7PCE4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_020920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01004247">
        <property type="protein sequence ID" value="ROT61315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCE4"/>
    <dbReference type="STRING" id="6689.A0A3R7PCE4"/>
    <dbReference type="OrthoDB" id="1191041at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF21">
        <property type="entry name" value="DEAD-BOX HELICASE 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="27"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT61315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="19395" checksum="F0D7AD7854C99122" modified="2019-04-10" version="1">MGLDDRILEAIARLRWGEPTLIQEKAIPYVLEGKDVLAKARTGSGKTGAFVIPTIHKILEWKRSATEQMVQAIMLAPSKELCRQIKENLSQLTTLCKREVRFIDVSPTVPLEAQRPLLVDKPDIVIGTPMRILAHLNEGNLMVKTSLKMLVIDEADLMFAFDHVKEIQEILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE01</accession>
    <name>A0A3R7PE01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative condensin-2 complex subunit D3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023574</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000711">
        <property type="protein sequence ID" value="ROT83248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE01"/>
    <dbReference type="STRING" id="6689.A0A3R7PE01"/>
    <dbReference type="OrthoDB" id="10263978at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026003">
        <property type="entry name" value="Cohesin_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF1">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12765">
        <property type="entry name" value="Cohesin_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="8">
        <location>
            <begin position="934"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="371"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1169"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1174"/>
            <end position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT83248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1221" mass="139305" checksum="8CA730600F7A28D4" modified="2019-04-10" version="1">MAVDGRAQQVLDLLLKFSVDKLDSAWIKNVIDADFTEVEDLPPEFEDLHCSTNFSGLFGAVIGSCRQWIDTMPALNDDSDRRTSTSNLNKSTEEERGEVETHTRFWIDLSENVNLKGLMSLLFFYIFRGQRYDAKEEDRELGIQAASLYFLLLSVPGSNAFRVFHPVMYLKALDILRLTTKLRVGAVSPKKGRQGGVRGSQRKSHEELMADMEDDDEAEITMLTPSEANKLIRSLNILLNDFLRLSQRFSLKHSPESMDETISILVDVSRSETHNAQGIFVGRHGPATVTALAYNAYVALQSICNPIHGKVPDKAEFRQKTAQSVVEILRYLPIQLYTKLMKWFFKFSHNEKAGHRLFLLEVISKMLGEEERQAEGSDNRPVQNSTQEVQPPLRTIREGQEEEEESEDDNSSSSFDNVRVDHSVNVPPDRNILSHKFLLSIIFSRCRDSGATVRSKALALLAECTFSTNPTIMLAMKQIFFRSRPTVFTTPHIENNNINMESPLELEDEDLDLPNASLVVSMLHRRALDDKVTVRKSALQVLENLMRIDNEMLTDKNIEVLVEHCRDPALIIRKQMVTSLTTLVLCYPEHSGVMSRWIKGVLPLILDPEMKVQERVVEVLDQLLFKPMLPHDHPKGNLPESKLPWHVLSGITKHSFHKFFNKAIMMWSKTEYVRPQIASIARTHIGNKYNEEVWTLLALLSNHITVKNIAFAVDYFEEHCQGESQVGAYTLQQVLKVLSNSIKHVPNDRAEALQKQLLEPVNNFLVGVELISSMMDTVTLLSYKLHGDEAEGQKDIEKWVAPLLKMCDDHLKHILFEKTDPIDKEGEELLFRHLFTLGEASMLCPHKVNKRMFLMLQSIIFHQSGVQRTGSAIIPSSQTQSSQPTAITFIPTTRVQALAVVTLGKMCLQHEDQAKRIIPALGKMLDSSTCSSLKINIVFTLSDMCVRYATLVDPLMPQVTACLRDPDLQVRRTTLTLLINLLQEDYLKLKGSFFYRILQCLTDDQEDIRSTVIFYITERLLKRFPKILCQHFIECIFHYNCYEEHESYNKFTQSTSEKELFSLAEEHHREDRHMIYRFMLDHMPDDQRFTITQRLCQDVLGGIVDGRIKLTPSSLPMLQDTLTVLSSDEIKLASLKSRPEDADQPTDQAEQAAMAGMAIKKTIISQSKRFPVRRSSDDQTGRHGAVEVSRRMRKNLRAWRLRKKGLTEFRKRSTGLCAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEV7</accession>
    <name>A0A3R7PEV7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein virilizer-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018337</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the vir family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003383">
        <property type="protein sequence ID" value="ROT63758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PEV7"/>
    <dbReference type="OrthoDB" id="2011702at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031801">
        <property type="entry name" value="VIR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026736">
        <property type="entry name" value="Virilizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23185">
        <property type="entry name" value="PROTEIN VIRILIZER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23185:SF0">
        <property type="entry name" value="PROTEIN VIRILIZER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15912">
        <property type="entry name" value="VIR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Virilizer N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="165"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="195"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1289" mass="149780" checksum="BD52AFDD531EE915" modified="2019-04-10" version="1">MYELLFFDTFSHEVSDKVQLDLVQFPRPVQVTEVRAIPLGARVQADFPGGVRLGATNPSQFEIEFFVNDLSKRGAGTFESVGTLQYNQHGNIQMDFEKKVPTDGLLLRGSYNTITLAVYGHLTKVQREPTPPKSTKRGEVVPHPPPEKVNTHDRIRDWLEDTQECRKQQPFSHDPSEDAQPEWDSKPPRSPVEYEEPKQWEEEHVEHNRDYDRERERERERDQRTSRGENRERERERDRERDRRRSAERSRSRERSWERSERSSSRRESRRESGREGDRERDRDRERERDRDYERDRDRERDYERERDRDREREKERERERDRDRDRDRDRDREKERERDRERDRARDRDRERERDRDRDRERRHSRESRDRFEEERLSTQEPLPSRGRRSIEEWDERRSERSDRSGRRPRTPLDSLPAPGSPYRGDNFSEEGSRGGTPREYREREARERERDVEDVEGFMYEEIMSDEEDIPEYPYTEEWLMEEWEDWLKPFSQDQFHLMEMNHLVSPTLTEYQVEHQKWKYRFEMEGPDLEEEPTQASKLESLLIETASPTSLRSRSLHGDCAEPEIRHVKAGVRLTHLLLQCSCEVTKQLLENNIMDKLYDLYHKPHMALSIKLLILKTIDAITRTELGLRYLLGEPLEADVEEKKPQKNGYELILELLSNVQQTRAKVALSAIVRKVHLLEVCQKLYEDTKALLLHLPPLDDDNRIKEEGPPEDDSMELDDAENRVVLPSNWSNNIPDSLIQAIKSCLQEIIRVYKYADQLLAQPHRWLPGSKQFQLPKNPHDPYPQLYLVFDHADLLNSLAVLLGALAAVQNGTLISEMKNLVECMLACGHGLNYMASHPRATATIARSLIQFGEDGREEGNDDNFLHQLGLKIIHIFHALQQLDALAQLTSSHNTDYSQSVTHFNMLTSLLLSSAGRQAIISARNTNFKDLTAIVPLVQTYLLLQSFPLGSQHITRAQDLQQEVISILLVYTQPVYSKAEGEEVLAKSLWTKMMSEIFKFLLTAPHTFMGVISLIIELLPLPLPIQTRTSLSEEESSQIINLRKLWSAHLYCLSSNIHEIIMRLGLASFPPLMHLLRRMCVALSDLAAPMALLVGRATLDLVMQAHRVDHRASGDDFGPCSLQTGRVLNMLALLVSHAPTKAAVLHLLQGGSPTLSATPTKGDDKYMGLVALWCRILNVAASGSHAHIQAQDCLLTIIQYLCDHENAMHVAQECTMQEGETQEPNTTSLTLSGLPSKDTLIPIIDALIDHLRNPHSSHQSIQQVLRALMRLMEHDYGFYHVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF81</accession>
    <name>A0A3R7PF81_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002540">
        <property type="protein sequence ID" value="ROT69638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF81"/>
    <dbReference type="STRING" id="6689.A0A3R7PF81"/>
    <dbReference type="OrthoDB" id="6363917at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026797">
        <property type="entry name" value="HAUS_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16151">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16151:SF2">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1122" mass="125024" checksum="D0FDF80B8B558AED" modified="2019-04-10" version="1">MASLHPPLDNAQDAGQVLYTSLLVLGLDAAGLEWSLRTPVNQKMFTRMNKKLGEHILHFLFVCIDRDKASKVFRDCWPLLDKRQESQFYKATFEWYKSLQQNYGQPVPTVVAKTFMSPGGPKFITILRTLTRIAHHATCTREDPERNILNFPTISRCPEKNRAMLTLLRASKQAHQREFILRQKIEQNVLKKVQEKAKELSGMYRSLCSQSDKAAASLQDALRQNVRLTQHQKETLPSRPLSDVQKEIQEDISKMNSEAKRLWDRVEVFRQVEESSWKILSPLLNGTTSLSHIDGSMYSVQVPDMIYKEHAAEINKLGLQGLYQEDKLDLLSLVQYANLALKSLLQIVQKTHSQAKPESTEELNVLMGRVASWNETVDQLTTKLNTLLPELMESVAVHRQHITLPVPTLESIEQDGKPNLCPPTPPLCLVNTPVVANGGPKYAPLMLTPGVHKPHARGPQKEANTTPSRMLSTHTMTRAARRSPKASVLYSSETHKDDSVLIVAGEEAKVAEAEEGLPVEMLTVDCRVRYQRKKQEELEALLEKYQPQKNREGKKTVIPKRTKIPKENKKPLENNALSDCSNRGTKKVLAQVEMNLKETNMKNGNGLAAGPDYGEDLDSSLINRLAEVVATDDNDSGAAELMAESLSCANSKEGSALDSGCAEGSSSETLLDAIEKMSITPRKKSESKLPQNRPGSAKKYGTPFRSITSQLSNSYTETPDISKGSEVTQPANLQVIKLIDFTPCGQPATNNCTPVGTPTRDPFKTPIQKQAAVGKNTDVSRQLLASLSLDKKEENAQEVPKDLMTRMSLLTQSPVRSAAIPQGSKILAKFSGLELQEASRDTRQKIPDSTETSRGAAIVELRHHAKTNLCSLIEQMQKMKQVHQEAEGIKESRPRVGSKSNFLSYVEKLKAEKNQINSGSESKHLLSLTKDIEINTDKKEPQSDAMTWNERSSVKETADKILTDNKTDFLNNMTRMQDLLGDDDDDEDTLTGSCCESKIFEETLEKEIFTNSRDIEKMLFKTPGRRSSYLSEDSVFDTLTDAILVGEAKSSILREEGAKAEARRESISTRRQSLASTGRMSVGSNRRLSDVFSVFQNRTSAECPGILDVSDSCLLSTSMDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ19</accession>
    <name>A0A3R7PJ19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cyclin Y</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ19"/>
    <dbReference type="STRING" id="6689.A0A3R7PJ19"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20540">
        <property type="entry name" value="CYCLIN_CCNY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000123">
        <property type="entry name" value="Cyclin-Y-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012399">
        <property type="entry name" value="Cyclin_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14248">
        <property type="entry name" value="CYCLIN Y, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028934">
        <property type="entry name" value="Cyclin_CG14939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="89"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="29633" checksum="F5E5DABA3F819C94" modified="2019-04-10" version="1">MLFQGGTGSEPNPEEVSEDPQCNLQHISEREPDDLDQDPSLHPTAGPLFLTKSKQVIENGLVRRRSRSHREGVPPDYDRHNPEHRHIYKFVRTLFNAAQLTAECAIITLVYLERLLTYADIDMTPGTWKRIVLGAIILASKVWDDQAVWNVDYCQILKDISVDDMNELERQYLVMIQFNINVPSSVYAKYYFSLRTLAEANDLTFPAEPLSKERAQKLEAMSRICEGKYAEQLCRNGHKKWSSLDNVHAASRRSVAILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJM9</accession>
    <name>A0A3R7PJM9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oplophorus-luciferin 2-monooxygenase non-catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001954">
        <property type="protein sequence ID" value="ROT74007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJM9"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="17102" checksum="E0E97D771F5FCC68" modified="2019-04-10" version="1">MCVWVARAREPTGAVSVEPGVDALLGQTQRTFSDLPHLRICSLLNRLSEIPAGAIEFNGNGFLFLDQNNISKIAVGAITGLGDGEVQLNENSLTVLDEDVFGAFLSAGATLEIDDNPLGCGCEIAWLVTNSAYMSLISPGASCYDGELLANLDPTIYEDFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNS1</accession>
    <name>A0A3R7PNS1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002160">
        <property type="protein sequence ID" value="ROT72409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNS1"/>
    <dbReference type="OrthoDB" id="6404151at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="739" mass="67014" checksum="3E0C6B1C7166B9EB" modified="2019-04-10" version="1">MRKRVSKTSPACDVCGQGSGHFPGDGHNHGHFPGDGHNHGHFPGDGHNHGASGSFSGSASGSFSGSGSDSGSASGSWSGSASGSGSGSGSGSFSSSWSGSASGLSRHRRSGGLGSWTGGSTSNKPGSGNNGGSWNNGGSTSNKPGSGNNGGSWNGGSTSNKPGSGNNGGFWNNGGSTSNKPGSGNNGGFWNNGGTSQRGSNKPGSYRPGRSVPQRRTREAEKLKSKLCPLCALGNLASGSGSVSGSWSGSASGSASGSGSGSVSGSWSGSGSGSGSGSGSGSASGSWSGSGSGGSGSGSGSISGSWGGNGGGSGSGSGSGSISGGGSGSGSGSGSISGGGSGSGSGSGSWCSGSVPSLEAWFRIWFHLWRRFRLVSGGGSGSGSISGGGSGSGSGSGSWGGSGSGSGSGFRIWFHLFSKVQDLVQEVVHGAVLAVVQDLVPSLEAVQGSISGSGSGSISGRFRGGSGRFRIWFLERFRICSGSGSGSGSGSISGGGSGSGSNSGGGSGSGSWAVLADLVPSLEAIRSGSGSGSWRSGSGSGSGSISGGGSGSGSWGGSGSGSGSGSISGGGSGSGSGSGSWGGSGSGSGSGSISGGSSGSWGGSGSGSVSGGGSGSGSWGGSGSGSGSGSISGGGGGSWGGSGSGSGSGSISGGGSGNCPGSCGGGSGSGHQVGGSGGGVAGAGSGSYTNKPGVGGSGHQVGGSGGGFGGAKGTSWSTAGAFGSNGAGGIGVKVDVRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQA9</accession>
    <name>A0A3R7PQA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative monocarboxylate transporter 1-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001994">
        <property type="protein sequence ID" value="ROT73761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQA9"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF306">
        <property type="entry name" value="RE01051P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="587"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="624"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="682"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="743"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="780" mass="84708" checksum="F98AA22261281F61" modified="2019-04-10" version="1">MPPHHTQMPPTIAHTHPTIRPTTPALPPPLHTFTHKHKRCPKVEAAPPGDSERERDKVSGGGFVSRVEMRGRPGLRSTTAHDTHTISLVGGAAPSSPSPPSPHHHLASTAHHGRGAMVMAGRTHNSNPPPGGGWVDASDAAAPDGGYGWVIVAANALLQMVLISTVAGFGLVLVESLSRGSSNAQVACMLALLVALANCLAPVSTGLGCYYSGRTLTLFGVILVAVGLLLCSLASSVVWQCLCYGVVGGIGLSLALPHGFMIGQRYFSGRRVQANALSMIGGSLGFMVMPPLLGYLLEEFTPRGGFIIWAGVVLHGALGAVLLHPVEWHLKSAKKEEQDEGGAQRNGAASQVRSDVSGSKRASKRDEMSEYDGFEDNKQLTPEDDDSEESDEEEPSTLPGLRMYQDRLPYVCAGRGMGLASDRPWKNPLTDTLQTNEYLERPRTVSIERSMEILPQIPEEAEEDDLFESFDQETGNERIEFLNRENDHRHRPVSFVSTKSADSFASVPTCETMFRSSDIFNQFGSALSAKTEKLKDRAQEEASKTLCQAIANPYKSRKQPLKPRVCCGMRLPRCREVVPFHILRHPLFVVAALSNVINRIAWIIYIAFLPALAVSHELVTEAPFLLSIFAASELLAKLLMAGVGDRGWMERRYYHILANFNGALAAIAVTLAWDFRSISLCVGWFGFSMGIIIALAQVLLAENLSSSHLSQTHGIMLFLTGISGLVIIPFAGWMSDIVGSYMIIYYVICGLSFVPCLLWGLVPCIAHHQGQDLKTPTDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSD9</accession>
    <name>A0A3R7PSD9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone H1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_000113</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001015">
        <property type="protein sequence ID" value="ROT81122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSD9"/>
    <dbReference type="STRING" id="6689.A0A3R7PSD9"/>
    <dbReference type="OrthoDB" id="1110759at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="6">
        <location>
            <begin position="147"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT81122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="297" mass="32649" checksum="7AD5F51EE00510EE" modified="2019-04-10" version="1">MRLLPRSNPRQLQRLACKNRDADLRSANKVASHAEVTHAHLHARKGRRASPCTRPQRARRRLQHNNLANNKEKHSLGPPPGHLAWGAPAGDSLLFRPRLREGDAEDAKDEAPEPPKKRASRMSVPKAAKSPKKAGAGVKKKAPKKKQHPKTLDMVVEAIENLGDRKGSSVQAIKSYILQNFKTVRADMLKSMLRRALASGLESGVVTRPKGQAETQAMSGRYLLGKAAKRDEDEEVMPKESKRVQEAKARAKAKKVAKKKAAAKRSPAKKVAKKPVAKKASPSKAKKPVKKGKKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTV9</accession>
    <name>A0A3R7PTV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microcephalin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001594">
        <property type="protein sequence ID" value="ROT76914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTV9"/>
    <dbReference type="STRING" id="6689.A0A3R7PTV9"/>
    <dbReference type="OrthoDB" id="2384350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17736">
        <property type="entry name" value="BRCT_microcephalin_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17751">
        <property type="entry name" value="BRCT_microcephalin_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022047">
        <property type="entry name" value="Microcephalin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14625">
        <property type="entry name" value="MICROCEPHALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14625:SF3">
        <property type="entry name" value="MICROCEPHALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="921"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="801"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="890"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="813"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1167" mass="125907" checksum="68BF68E73E99BB2B" modified="2019-04-10" version="1">MKRGGKGSTRQSQDMHSVLFNQKSLTNVDSVVVPETPTNLTCARPGAAPSTSMMSVMETPENEVGCGAQGLPHTRFKAQAGGKSEVPTDSSSDRDEIDDSTVLDITPDLKLGKRRNLMSILESEDSFARSLKSQRTKNSSMLSGVQATSQQQQPEEDDFNLFAVSPVKKSRRRKSAAHVIMPFDLNDSESLTTKLRTIEEGQHRARRPVGGPGVEGPGSEKRQTAARGGRATGRRKSLIVPLSTDSSEDDEVILNTQRKNSKPRGSHPKEGPKKNRSCSRETVQNKGGTERSTISKGSTNSGINNGIWSAQNRSSDATKIFDSEDLELTPIKTSSQEISIRNIIADLESQPAAMDETLPQALPAGCGVAGMSFQNFSTRSFRLLQAQLPEEAGGAEGGEKTAGGKGGAGGTHTDWMEPSEASESAATEPDVTVILRGVIAYVEVRMGSDNRSQVIKEQLKVLGAEVRDRLSPDTTHPPPDPKGQRRAAAAALVTLRRKRRREFVSPRTDSVQRKRVPVGQESPLCSTDPKRRLKCSSEDSSSDTGVEGSCGGGKSMQQDAVSRTTTAVAVRGMDTEKDGTKSSESLALLLSDSSQDRSGSSEEAVLGSRRSSSRRRKYGDNTQDSGSEESCAVKKKSSSPGKRAISLVNNFVSGNLEGTVVAGPAHGEVNTEQEGSTEPGGNKMRRQSILKKAESMGKQGGKEKRKSVSIGGADILEVEVLHSPVREKAVNQRLPPTLSSPSFGVTSSQLPSSLPASQLRGHRLFNMDPVAPSQDLIVPSTPEDPKKFLRRPYTDLVIRGSKTQRTALKNQKGGSLSSLPLPRNPSPGRRAAGSSQVKKSTRGASTVPVRRSMRLNAAPVKKKSEDEDVFMGSEEEEEFLARSRIPLLPRPRRSTEEFQHAGELKAKGKRGRRPKGDSLPSLYVSSVHSKEKTSLLPVIMKLGGFRVTSVIDASTSHVVCGEARRTLSLLQGIARGAWVLDSSWVYESLELGRWAPEEAFELFMAFPGAKISRLQKQERGRKGNYTQTLFSGVGSIYVSEGCTPPTDQLRNLLELTGAKVVSHSRSANLAIGLPPSSSSAPSGSSGTRPLKVTHLSEKVVLGEGLAYLAWIHEPWHSLGQPHFPFPSTLHFISPPSLRLSTSDFISTLPPLPIPTLFQVPLSPRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWE5</accession>
    <name>A0A3R7PWE5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000491">
        <property type="protein sequence ID" value="ROT84829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWE5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="64442" checksum="124A840BD85532CF" modified="2019-04-10" version="1">MGSPSASPDSPPSLSLSSLPPPCLNPLPLTATLPFLIPPPHHPIPTPSIVSIPPPHHPHPHPPDLHLQPNQPLTNDKILDVKPKLTPTPTPTLSSNPGHSRPRREEQGDTAPPSVATLPPAVGTQGYFRCLKEVPRCPSSGLRVRACAVRGAMDYSGPGSLADIEAAHAMSDEEDRCNDHWPPLESRSCHELAPDVAGPDHRPRTPAATKRTMEHDSDTKSTPSSPAAKTFKLVKLLLITVRQTTLYLALHLKLCPFAPRDKYVKLVFQENPSNDVKIRWLSEVTRQPAFCLDRELAEVKMSAVTSRFVYISRQREDMIDKDSIDRPRKFPTYLITRYPVGVEPSLAKELPGVYTVRRFHQNGTPINRLVVTWSLREPPPPAVNFTFLPCLPPCELRRMKDEQPWCFKCWGIGHISRYCSSSDKCAWCAAGHATRSCPYRTPPTPTAAVASTSTSDTSPPPVPDTSQWKCPRCHMPGVNVWHGCAKQSRIALPQYSTPPQNATPPPPTAPPYSPQADSAEVVALRKAVASLEVRCTALTARFDAIDSRIDNLVSQQATSASTLASLVESHQVVITSVTALTEKLDAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWX4</accession>
    <name>A0A3R7PWX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Cytochrome P450 2L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_017766</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000328">
        <property type="protein sequence ID" value="ROT85293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWX4"/>
    <dbReference type="STRING" id="6689.A0A3R7PWX4"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF397">
        <property type="entry name" value="CYTOCHROME P450 2U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="533"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT85293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="588" mass="67017" checksum="D39DA71D48D1DF64" modified="2019-04-10" version="1">MTTRTRSQLAAPIPSSSPRATHDDWPVTPPASQWMVRRLSLSRKLGRWAKEGISLDPATATLKTCWSRFCSASRSCSSCISGATDRRLSRQIPHHRLRIRRQRQREKTAAEVRRRVQHPLRRRRPGVPVQLQAHQGSLRQDRVRGQTQLEGVIFSSGARWQASRRFLLRQLRDLGMGKSSMDAAVAVEAKALVEDFRRIAGSPTTLPDSISLVTLNVVWQLVASRRYNLDDAEMLRFLRLIRVFQEDVVFLVLPEFFPWLNYIPAPLMRRLSRQDWLQKSAKQANDMMQEVVDQHRASLDPDNPRDLIDCYLLEMERQKDSPSVIFNDTDLRKNIFDLFSAGFDTTSNMTRYVILYMAAHPDVQRKVQRHIDEVVPRGEVPASRHRARLPYLDATLQEVHRMASLVPLGVSHAAATDVRIGEYVIPKGTPVSACIGLCHKDPRYWDEPEEFRPERFLDEEGKFVGSECEGFTCPLGIGWGTPGVRVHGLCTRTSELDDEKPEEFRPERFLDEEGKFVAQREGFLPFGVGRRSCLGEALARMELFSFAAALLQSFTFAPPEGRKVDLGYTMLPGINVPKVQELLILPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXU5</accession>
    <name>A0A3R7PXU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative thiopurine S-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_021881</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000047">
        <property type="protein sequence ID" value="ROT86019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXU5"/>
    <dbReference type="STRING" id="6689.A0A3R7PXU5"/>
    <dbReference type="OrthoDB" id="276151at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008119">
        <property type="term" value="F:thiopurine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10259">
        <property type="entry name" value="THIOPURINE S-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10259:SF11">
        <property type="entry name" value="THIOPURINE S-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT86019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="263" mass="30478" checksum="87BE18EB71AAA291" modified="2019-04-10" version="1">MCDHEPRPVDTRAICEQEAEVVEAADPWQEFYGDSLFLKRDWDLEDWRSYYDKMPGWDGCEGTGVGVSHFAEEVFRRREASRAFFPLCGRTEDMKWPPPSPGPTTWTPVVGLDGVEKPVRHFFEKHQDLEHSVEELEYGKLYKSKDRRLQVFVCDIRDIALVVLGKFDVVVDCGAFTSIHPRDRAKYVETVTSTLQKDYRYFLEVCHGAPPSATGQPNSISFREVKREFGPSRKLKFLSTEDISEEWAVDTFFQTYLVMEPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZA9</accession>
    <name>A0A3R7PZA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003281">
        <property type="protein sequence ID" value="ROT64272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZA9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="43964" checksum="F5D19D8E796BF03F" modified="2019-04-10" version="1">MHLILFFRLLTPRPPLHLYFPLFLFLHSSSSPFFSLPDPPPPPPRLSLNPPTPLGLGTSFPPHPCPFTHLTPPPPPFLVLFPIFFSLPGQFPPLHVPSSYSWFFFLIPVLSLPDRPTPPLILPPPVFPIPYPTSNFVLLYPNLTPSFPRFLSSPSPNFAFSTPIPRIRLSPTPIHPLNFVLLYLYPPPPPSLSFPHSPGSVPLTSSFPIPDFPSRRPSAIPVLVLFPLSCILLPPPFPSATFVFSLSPLPLSRLHSLLLCLFALLPSSIDCHTVSSPSRFPSLYPSSSSFFAAFSSPLYLPLPLPLFCSSWKSQHLGSRLRAVMQGKLVLTIRCYLSRCGKLYSFLTLHVPTPCVLHTLIKSRQGGPETICSFVLESHGRLRRGRWMEGWGWGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q072</accession>
    <name>A0A3R7Q072_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000799">
        <property type="protein sequence ID" value="ROT82599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q072"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018697265" evidence="1">
        <location>
            <begin position="18"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="169" mass="19183" checksum="430D534C7A494EEC" modified="2019-04-10" version="1">MVLFLALSCLLPGLALTMSVEGRAAPDLSTYNSVEERVQPDLSTYNSVEERVHPDLSTYNSVDERVHPDLSTYNVDEMYLRGDTEDSGPVEEPFEQTNPDVVDGKNLFEKDIMLTEAQWEQVLARKGLAAESRRWPEDASGTPRVKYRFADACVRMCFRVMHTILPFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QEL2</accession>
    <name>A0A3R7QEL2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tetraspanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017135</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003168">
        <property type="protein sequence ID" value="ROT64930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QEL2"/>
    <dbReference type="STRING" id="6689.A0A3R7QEL2"/>
    <dbReference type="OrthoDB" id="9972904at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000301">
        <property type="entry name" value="Tetraspanin_animals"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF252">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002419">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002419-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="209" mass="22917" checksum="714C95B6D8B9EA2C" modified="2019-04-10" version="1">MLAAGILVKVEVYKYVEVSAEFSATAPYVLVATGGFMLLLGILACCCTAKGQPVLLYIYAAFLLVIFVIMIGAGVSTWAYRKHLKNSYEDGLTRAFTEYDRTPTMTSAVNTLQNVLRCCGIQNASDWVAMPYGQSHDPPYPPSCCREEQENICVALHPHGCYSTVIHFLESSTGVILISALSFACFQFVGVILACCLARNINRAKYEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFI6</accession>
    <name>A0A3R7QFI6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003027">
        <property type="protein sequence ID" value="ROT65850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFI6"/>
    <dbReference type="OrthoDB" id="549017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="121" mass="13718" checksum="05D7332894B30C58" modified="2019-04-10" version="1">MNMKNFRLNYPDVYFLMVGKSKGSYNDILLDISKDFFTNNVLEQEDFATVVSKRVLESKRRECPSVFGSSQASVPLWLVPLCDWFLVFGPFTVIGSCLWFLCSDRFLVFGSSAKDPSAFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QH39</accession>
    <name>A0A3R7QH39_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Ribophorin-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_014726</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the oligosaccharyltransferase (OST) complex. OST exists in two different complex forms which contain common core subunits RPN1, RPN2, OST48, OST4, DAD1 and TMEM258, either STT3A or STT3B as catalytic subunits, and form-specific accessory subunits. STT3A complex assembly occurs through the formation of 3 subcomplexes. Subcomplex 1 contains RPN1 and TMEM258, subcomplex 2 contains the STT3A-specific subunits STT3A, DC2/OSTC, and KCP2 as well as the core subunit OST4, and subcomplex 3 contains RPN2, DAD1, and OST48. The STT3A complex can form stable complexes with the Sec61 complex or with both the Sec61 and TRAP complexes. Interacts with DDI2. Interacts with TMEM35A/NACHO.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endoplasmic reticulum membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the SWP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002834">
        <property type="protein sequence ID" value="ROT67200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QH39"/>
    <dbReference type="STRING" id="6689.A0A3R7QH39"/>
    <dbReference type="OrthoDB" id="432292at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055375">
        <property type="entry name" value="Ribophorin_II_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055374">
        <property type="entry name" value="Ribophorin_II_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056790">
        <property type="entry name" value="Ribophorin_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055373">
        <property type="entry name" value="Ribophorin_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008814">
        <property type="entry name" value="Swp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12640">
        <property type="entry name" value="RIBOPHORIN II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05817">
        <property type="entry name" value="Ribophorin_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23861">
        <property type="entry name" value="Ribophorin_II_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23860">
        <property type="entry name" value="Ribophorin_II_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25147">
        <property type="entry name" value="Ribophorin_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="17" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="601"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="634"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II N-terminal" evidence="13">
        <location>
            <begin position="54"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II second" evidence="15">
        <location>
            <begin position="296"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II third" evidence="14">
        <location>
            <begin position="408"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Ribophorin II C-terminal" evidence="16">
        <location>
            <begin position="559"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF25147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT67200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="661" mass="71470" checksum="A375B74DE4F2D2CD" modified="2019-04-10" version="1">MTVPEAEPSFYIQGLCPVRLLTLPSTGNRSMRRGALVILALLGVSSALSPSTYLTPADKERLKLVLDPAWSLSDLAQVLYASAGYKHLGQPIPNEQGVCNFVKSSAGDGATVETLFLASSAGKALGCPVAATAASKQAVSDAIREGASPLELFHAVTAATNLGVEVDVAKVLRATQMALKKDDSVLSLGYAFHVGSQLRGEVSSIFERIEDAIVQADEVDGRMLQFEGGLSITALVLSGAYKLAENSNKAPPIKPDQAVKFANYLMSRKSVQVPKGVYYLLEAVSMFTSNRFHIPVAITLASNVAVSADAPRVQVRVTDLKGSSLGSLRVVADSATRDSDEVVIVSKEELSPLAGQDGVYEFDVMSRQPERGFYRLVVSTVTSDSRLVGHMAAQLTFKVLTAIDIQGVEVGTADSDRSTAPSLQKLTYPNKLPSELLADQHQRVLLRFIVRDLASGRSTEVHQAFVKITHIESKREIIFVAETDSNDVYKFDMDVSNNVKEFGGVSGSYSMELIIGDASISNPTLWHIGDVSLSFPEGSVSSPSQDYTYKARPEIQHEFRKPDPRPSTLVSLTFTILCLVPLLLLLAMWAKLGVNLANFPLSLSSVVFHVGLAAILGLFCLFWLQLDMFTTLRYLFMVGVVTFFSGNSMLSNIAANRKETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHX6</accession>
    <name>A0A3R7QHX6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative cysteine proteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013855</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cystatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002725">
        <property type="protein sequence ID" value="ROT68025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHX6"/>
    <dbReference type="STRING" id="6689.A0A3R7QHX6"/>
    <dbReference type="OrthoDB" id="6357437at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00042">
        <property type="entry name" value="CY"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.10:FF:000004">
        <property type="entry name" value="Cystatin C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000010">
        <property type="entry name" value="Cystatin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046350">
        <property type="entry name" value="Cystatin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018073">
        <property type="entry name" value="Prot_inh_cystat_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46186">
        <property type="entry name" value="CYSTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46186:SF2">
        <property type="entry name" value="CYSTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00031">
        <property type="entry name" value="Cystatin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00043">
        <property type="entry name" value="CY"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54403">
        <property type="entry name" value="Cystatin/monellin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00287">
        <property type="entry name" value="CYSTATIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0789">Thiol protease inhibitor</keyword>
    <feature type="domain" description="Cystatin" evidence="6">
        <location>
            <begin position="159"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Cystatin" evidence="6">
        <location>
            <begin position="308"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Cystatin" evidence="6">
        <location>
            <begin position="452"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Cystatin" evidence="6">
        <location>
            <begin position="590"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Cystatin" evidence="6">
        <location>
            <begin position="812"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="741"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="925" mass="104051" checksum="FAA276F788DDD5D0" modified="2019-04-10" version="1" fragment="single">CAETEDDNDFNVWGIINPPQPTGAEVPVQTLPQGISEQQLGLEAFNYVDRGSDSKFRGELVSYDIGRILFDPVLNMTQVQVNVEYGFNLCLRSPDEKTDPRVCPRDNHRDHYVCSVTVVHNPNQIASLDVVPVVEDDDDIKCERRRSVDEELVVPVRAPCLGCPQAAPLNDPTILEIADFALKEYDRASNEDELHMILRLVKAQTQVVAGVKYYLTIELAETHCKKQLTGVDVNRTFCPQDVTEETEICDLHVVDQPWVPSRDLVASQCYDKDDYPTSTQDEFIVPVALGTGLGASPSVGTTFRTSPPTHSGQKPLEINPQTLEIARLVVAEYNRREDDDEYYKFVKLHEASSQNVGGTMYRVVVELAETNCHKLDPTLGNGEHCIINPSEDHEVCKAEVLVQAGAPAPGNQRLVSFACDDLDDYLRETLMPTLSSVDLMDHPFLNLPQGRTNIPGAQPVALNDSKVHEAAAFVVEQYNLRGDEDELYVLTNVVSANMQQAQGITYLLEVELAETHCKKYLPIADPSRCVLDHGEEREICQAEVMMPSAPGQAKQLTKLYCDERDDYYLNKIRGKIFQKSGADPSTFRTGAPGGQWIEMDVNDRSLKKLGIKIADEFDFRSDEDNLFIFQKALKARKQVTSGVRYHVMVELVETICPKYKRRINKARCAPDIGEDHMICEAIVMVQPWLDRQDVMNLHCTEKEHYHDGDESFEVNLPSVHPTAHARPVFKSQFMVRDSIESEESNERFYDPSGRTTFGSDESFEDDSDELTQHGGAKRFYEPSGRTNIHRHDSDEDDSDELPSFRGKRRALGGPGGLSLVDVNDSGVQENAKFAISSVDSLSDDPFARNVEVLEAHKQVVAGLNWHLKLKVYWTTCRKGEQVDIDACEKDTERPSNICNAVVYEKPWMNFKKVTEMKCRPENAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKA8</accession>
    <name>A0A3R7QKA8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_011548</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002456">
        <property type="protein sequence ID" value="ROT70179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKA8"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="66"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="322" mass="36138" checksum="D8F1327F053AAAF4" modified="2019-04-10" version="1">MTDANAASLEVAEREHPPPEGTTPVPLPEGLLANDAHYLYKGCVFPGTILRSGMFEEVMNFEFRSTDVIVGSFPKTGTTWTQEIVYMLTHGCQKSKPEDGTLETRFPFLEFPFPGVRAVAAMEGPRCIKTHLPRHLLPKSFASSGAKVNDLRDYVTRNPRDTAVSYYHFTQLLTVASFKGTLSDYVELFLEDKAMYSPFMPHVLGFWEARRDPNLLFVTYEELHQDALKAIRRIAHFLQASPFSVEASEEQLEYVAACTSFASMASNPSVNYEHWKDSGFCHKDKGSFLRKGKVGGWRRVSAPSRSRPSSGKRAIVKVSLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKC8</accession>
    <name>A0A3R7QKC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ-like protein subfamily C member 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011499</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002449">
        <property type="protein sequence ID" value="ROT70217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKC8"/>
    <dbReference type="STRING" id="6689.A0A3R7QKC8"/>
    <dbReference type="OrthoDB" id="18010at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055225">
        <property type="entry name" value="DNAJC11-like_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22774">
        <property type="entry name" value="DNAJC11_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNAJC11-like beta-barrel" evidence="3">
        <location>
            <begin position="99"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="DnaJ-like protein C11 C-terminal" evidence="2">
        <location>
            <begin position="356"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="494" mass="54937" checksum="7E3A4792564150F1" modified="2019-04-10" version="1">MTEDMEELQDDGEDYYTFLNISRTATEEEINNICVSVVLYHPVSLPDREERRLQQRTNPKSSVTMTVNATDLFNIYDEESPYMDLRDIFGLPHIEISGMSLNQSIEAPLTSRDTAILSGNLSSHNGNGSGGINCSVRRITSEKGWGELELGAGNGLNIAFKGFRNFSRGVFGNGSVLTHFTPNGLRVGTVATIANQLDKHTVGYLTWKAGMQSGMNTMIIRDTASHHIVFSAYIGIPHTYAALSFTHKMPDNDAKVKLTGKAGTFGAIFEYGAEKKVSQNSSLAASLSLGVPTGVQLKVKLHRASQTYGMTILLCEEILPAPIMYGTMVPLVSWLAVHKLVIQPYLRQRKQTELQKQRENNKSRLLEKRREANAAVDLMRETVKRIVDQEEARKGLVILQALYGQLVTEGTQQDGCEVSEEVVDVTIPLQCLVKDSKLILQESSKCSLPGFYDPCPGEDKNLRVRYLFHAVTHEVTIKDTESLRIPKQSHRLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRP4</accession>
    <name>A0A3R7QRP4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Muscle LIM protein Mlp84B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_005723</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001738">
        <property type="protein sequence ID" value="ROT75744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRP4"/>
    <dbReference type="STRING" id="6689.A0A3R7QRP4"/>
    <dbReference type="OrthoDB" id="1679758at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042805">
        <property type="term" value="F:actinin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008307">
        <property type="term" value="F:structural constituent of muscle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060537">
        <property type="term" value="P:muscle tissue development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09326">
        <property type="entry name" value="LIM_CRP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000001">
        <property type="entry name" value="Cysteine and glycine-rich protein 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF35">
        <property type="entry name" value="MUSCLE LIM PROTEIN MLP84B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0440">LIM domain</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0517">Myogenesis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="9">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="9">
        <location>
            <begin position="109"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT75744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="188" mass="20433" checksum="68E21BD2148F6707" modified="2019-04-10" version="1">MPFKAPENPKCPKCGKSVYHAEARVVGDISFHKECYKCSMCNKMLDSTNSNCHENILYCKTCHGRKFGPKGYGFGGGAAGLSMDTGAHLEKKKRNELAPYKPPKAKAGEGCPRCGGKVFAAEEMLAKGKSYHRTCFNCKNCRKPLDSVVHCDGPDKEVYCKVCYGKKFGPKGYGFGHGGGTLQCDPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QV73</accession>
    <name>A0A3R7QV73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nose resistant to fluoxetine protein 6-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001248">
        <property type="protein sequence ID" value="ROT79421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QV73"/>
    <dbReference type="OrthoDB" id="207378at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="361" mass="39970" checksum="69691A9510558922" modified="2019-04-10" version="1">MLWIIVSVQYEVATDYITNTVDALRCLDHCWYTAVDMQLLLILPLLLLPLGLHRVAGLCWLGAVSLGSILTPMSIILVHDLPPVPLHVMSESKKFEYMWRVYLTPWCRAGPWLAGVWTALALYDRALAKVKIPKLAVFLGYLAAISLGLGLVLGLYPYNHVMPDKSYVDNPAMSAAYGALARPVWGLCVAWVVFTCHTGNAGVVNKVLSYPGWRPLGRLTFTMYLTVPLVQLWWSSVQFQPVYYNYLEKLFQSAGVAFIAGVVAILLSCLVELPLRTPSLLLILTPPYPSPLPHLIPLPLPHLLPSPSLSPTYLLPLPLPPPPTYSPPSPHLLLPLPPPPSSFYSPSPLPFWISPFVIART</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QW00</accession>
    <name>A0A3R7QW00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001130">
        <property type="protein sequence ID" value="ROT80322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QW00"/>
    <dbReference type="STRING" id="6689.A0A3R7QW00"/>
    <dbReference type="OrthoDB" id="995477at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.310:FF:000001">
        <property type="entry name" value="RNA-binding transcriptional accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.650:FF:000001">
        <property type="entry name" value="S1 RNA-binding domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.310">
        <property type="entry name" value="Tex RuvX-like domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF10">
        <property type="entry name" value="S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12836">
        <property type="entry name" value="HHH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="716"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="770" mass="87411" checksum="B7499697B21D5E4E" modified="2019-04-10" version="1" fragment="single">MSTNNALEDSIVILEEVEGTRPLAGGTGIELEVLYDGQAEEVQHVAQKTGRGEVGGAGTLKYRKRIPDNDVEIVFEWDPAKVIAERQSVDEWVARNVISMFDQENTLPFIARYRKERTGNMEVEKLREIQNAYSQLKHVQERVLKILKGDRKRLPEDRKASLLRATTMHEVEHLTAAYKGSGKRTYAERARELGLEPAALEVMQGTHNKFSNRQELYSLMDLNKEGLRTIEEVEQGLQHIIADVISKDPQVLDCVRQLMKLCKPVLECNKARKQMKRDQGKMVSRGPGPSDDLCAKYENYFEYKNLAWNTKPHSMLAMNRGEHQGVLSVKVAIPDNTYVHFFNYCQQKWLGMAPPHYYRTQLVMMSIEDSWERLGEKLLTTTIYPFRGNQHLQVEDWCKDHNARTLREIVHKYRCELFAIGNGTGCRETETYLTRLIAQKCFDPYNVQYTIINETGASQYSVSPEARTEFPGLDPNHISALSLARRLQDPLLEYIKVHPMHMGVGMYQHDIPERILHASLDSVMTECVSFVGVDINSASEFVLRKLSGLNKPRAANIVEYRKTKGPFINREQLKSVKGIGPRTFEQCAGFIRIMPETLEMEINKTPQGKKRAEKEAVSPLDRTMIHPESYGAAMKFLSIVGVRSQDIGADHFIRTVRHFMPTTTLDALSEQCETTLPTMQLIVEGLTQPLDYDIRAQFEKPLFRKGITSIDDVALGTKLTGTVRNVTHFGAFVDVGLGNDGLVHVTKMAGVRLELGNIVEVSVISIEKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWP1</accession>
    <name>A0A3R7QWP1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001047">
        <property type="protein sequence ID" value="ROT80941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWP1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="43053" checksum="E1B79038EE3E6C1E" modified="2019-04-10" version="1">MSQSLVAASGEFPVPLPASLDRCVLPPFSLPPPFLFCYSGTSPVLPPIPTRTPLPPLPHSNPLPSLSLLLPPLPLNSTPSPPLPLTRPLPPLPLTPTPSLPCSLGPPLPLTRTPSFLFTHSTLSLPLPSLNPLPLLPSLDPLPPFPSLDPFPTLPYTRPPPSHPPHSEPSPFPLFPPPFPHSTPSPSNTNPCAAPSPAMVFREGPGPHSLPPPFPHSTRLTPPSPQTPFLTSLSRPSLPSLQINPSLPLPLPFLSRRPPLLLPLHSTPSFSFPSLRPPSSPFPSTRLPLPPFPPSPSHSPPPSPSPSLDPLAYPPPHSTPCPLPPLPPPHSPSPHSTPSFSFPSLDPLPLTRPLPPRSPSLTRPPSPPSPSSLPSLGLSDPASRRGEPRAVLAEGKLGMDWWWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIU9</accession>
    <name>A0A3R7SIU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003532">
        <property type="protein sequence ID" value="ROT62863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6621371at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="876"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1134"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1160"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1225"/>
            <end position="1285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1350" mass="145253" checksum="6A02638C737F004C" modified="2019-04-10" version="1">MSPITPFPPPPIHPSLHSPPSLHSPLPSITLLPSITSFPHYLPSIPPFPPLPSFLLPPFPPFPLSPITPFPPFPLSPITPFLPTPSLPITPHFPPCSDSPHPRFLRIPSLPFPPHSHSPPPPIPPFLPTPFLPPSPPSSPLPLPPSPPILPFLPTSSLPHHPHSPPFLPTPTPPLPPHFPLPLPPHSPTHSLPPSPPISPCSDSPLSADHEPVAGAAPLSHQAAFHKISIRPKRTHGAPRMRRSTQIGGQRSLPTTPEVNEDASTKSGTPSKVPTSVSPSTPTELTSHIAYDEDSSPSHEQHISIERRDSEKKDKEEKKDEPLLQRLFGSVRSGRRRSRGNGDDSRENSVSPLRRGGDQRASREKRRDSSGSRFSMLGRASTKAHNDSHPLPPSGRARDPSRERPYKESSSSPPQTPRSSSVEGRLESTGPGQQSAFQISSYEDRPSRPFSGVRKVKSFREVAGQPETQREPIHRKVSSQSNVEERISISSKISRISASFESLDNESDSKLTHTANSSGTSSTEILSTSPQRSSTDSLTSTQIPGVFIRQHSQNQHRVGITKHQDQFQQSHYLQQGNQDSGSGPLSLDSSISLHTRESDEHMRKASSVDHVSYVIGSWHPVKDSEVPDPVVHKTTEIKQTLVSKNISAEIKPADRVSPKQALRSHSLQGDDAGHPVSGTDESEPEGERTPRRPLKKEPSMKRVPPREVEPDPVPEFMRIQLNRVESKGQSVVYETEQEKGIKVDGKDKEIPRSQADLSVKETSMTELSDGAAVYRSESKDGKSSSLNKRGSAQFSKGSLRDVSPSSGNVEIVDSDSNVEGTTPDSTVERVVLRKPLVSERAPLMERASSMSSQGTSSKNEQPELFKVFARRSFKVKDIEKEKSQESDNEEEENIEETSEVSEVTVIPTRAPVASPASPIPSKETALPATSISLTAGHQKPSLNTISFNRKSVGNPALAFCPPPITNTSTAAPGSPKATVLVVSGNTSPLPMSTDVTSNAVSTSRNISNITTTSSTMISSSASRSITTITTPNNASVNKPVTAPIHGPTVRSSNAMVTSEAGVTVTTSNSSIYSKIISRSSSVTATNEVNKNEQESAPATPPPAKLSVSGRSGSSIVWPPRPQPQEETQPAVHLSHTSHTNVAGLQSKKVSRSPSSVSESEDVKPAEVTESKEGPVEISPLDIGAARRRFMSGGKDRPQAPATPPSQNVSSVSTAPVPSSPGTVSLLSKPSSAPATETRSAAPSFTVTVRTQSPSSVAHTDSQAPTTAVTNTLAENTVNTSVSGSPGKSEHGVAQQAAEDWRVLVRQRREGRLKQSKTPDTEEIIIETRPPVSRNSKVLEMANNFQKLQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJY3</accession>
    <name>A0A3R7SJY3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peritrophin-1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_017895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003305">
        <property type="protein sequence ID" value="ROT64188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJY3"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="6">
        <location>
            <begin position="205"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT64188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="322" mass="34753" checksum="D4F5A26C9029BC38" modified="2019-04-10" version="1">MRFIPNISSECERQIDPKKPSLIFPSALISYFRREIRPRGLRNLISCLSVATETSSKRMWGFNPSPRRLLFDVTPRSYKQDARPTNAFERIVLNTRSSFNVRHLSVYLHLGNRLVVCLSLLVVAGVSHGLPAVVTAPPQVAAQCPYTPGPILCCCPIVSGEPQLPLSPATPTVVPVSPICPVNRAATAGVSHGLPAVVTAPPQVAAQCPYTPGPIPLLLPNPVDCGSFYMCSWYGTALLQHCPPVLHFNAKLQVCDSPEHANCIERTTAAHVSSTTTAAPVSNGTTAVPVSNVTTAVRSPMGPHYDKPVPVPIWPHLFRIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SP43</accession>
    <name>A0A3R7SP43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative BCL2/adenovirus E1B 19 kDa protein-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_012758</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NIP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SP43"/>
    <dbReference type="STRING" id="6689.A0A3R7SP43"/>
    <dbReference type="OrthoDB" id="5857140at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097345">
        <property type="term" value="P:mitochondrial outer membrane permeabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010548">
        <property type="entry name" value="BNIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15186:SF5">
        <property type="entry name" value="BNIP3, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15186">
        <property type="entry name" value="RE48077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06553">
        <property type="entry name" value="BNIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="126"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT69101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="284" mass="31769" checksum="63A23EF4A88F899F" modified="2019-04-10" version="1">MFKEQNSYTRSPRCYGGTTSVPTLAPSPSLAPILRLGASQSMVSDVIARAELLPRPRLAICSRRRAAADVFEWNLSLHARVPLVWLGFNMQEESWVDLSNQPSSPDRVTPLPFGNGEEYLRLLREAQKDSNQSSARVSLASSRRDTPRDSPHDSPKSPPNSPNTEMATDPEEAAVLKGVYINYYNKEGDFIRVEKNTETDWIWDWSSRPDQTPPKEWRFSHPRKGVSRGASIRRVMVGNSSLFSRDVLYTLLITNVLSLILGTGIGIWLSKRSGSNVISTLPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQM0</accession>
    <name>A0A3R7SQM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative octapeptide-repeat protein T2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002373">
        <property type="protein sequence ID" value="ROT70894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQM0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="49857" checksum="DB9332F93CC5E96F" modified="2019-04-10" version="1">MSVYKVARAGLLIAHKGFPRPGGRRFPRQEQRSRGQEAGEPVPRPGGREGAEAAESRGQEAEIPRPGAGGVPRPEAADSRGQEQRSPEARRQRSPEARRQRSPEARRQRSPEAQEAAESRGRGAAESRGQEAAASPRPGGKRIPEARKQPRGQEAADSRGQEAADSRGQEAAESRGQEAAGPEEAADPEARRQRVPRPGGSGVPRPEAAIPEARRQRIPEARRQRIPEARRQRSPEAKRQRSPGARRQRIPEARRQRIPEARRQRSPEARRQRIPEARRQRIPSPEARRQRIPEASEESRGQGQRSPEARRQRSPRPGGSGVPRPGGSPGPGGSGVPRPGSGVPRPGGSGVPRPGGSGVPRPGGSGFPRPGGSGFPRQEQPPRLLLLYLALNPARSRRPLAVPARRDEGRAPARASRARASLTRKQIIDPLRMTSRRCNGLCWLCEGRRGVPRECQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVB0</accession>
    <name>A0A3R7SVB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Haloalkane dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004622</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001609">
        <property type="protein sequence ID" value="ROT76807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVB0"/>
    <dbReference type="STRING" id="6689.A0A3R7SVB0"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051340">
        <property type="entry name" value="Haloalkane_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002043">
        <property type="entry name" value="PRK00870.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42977:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42977">
        <property type="entry name" value="HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="95"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="353" mass="39623" checksum="E604378A490A79E2" modified="2019-04-10" version="1">MSNAKHLLKRLVLFPLIILTSQLLHIAKQFILTIIDLFVQKKHPGVVRTPEERFQGLEALGYTFKANYVELPIGGGKTLPRVHYIDEGPSDAKETILCLHGEPSWSFLYRHMIPVFTKEGYRVIAPDFIGFGKSDKFTYPDAYNHDLHRMTLRLLLDNLGVSNVTLVCQDWGGITGLSVVKDSPHFFSRLVVMNTGLPAGTQLSLSTIARITPFLLWRSLAQLFGTALPVYHVFKKAVRNAQPAVLEGYSAPFPSSEYKAGAAKWPLLVPLTSNTPVAVDMQETRDFLRQKWKSPFLIMFSDRDPITRGQDKTFLKLQPHATCKTVHGAGHFLQEDKGEEIASHIVSFINGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0K5</accession>
    <name>A0A3R7T0K5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000572">
        <property type="protein sequence ID" value="ROT84254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0K5"/>
    <dbReference type="STRING" id="6689.A0A3R7T0K5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="425" mass="45534" checksum="13A4F26E201764D0" modified="2019-04-10" version="1">MPPSSLSNFHPSPSSTLSYHLSLLIPSRRLPPLSNYLRPPPPFLLSFRPPSAPACKHSSRKHAYTWEVLCGRLCCFPYSPSPLHPPPPPPPLPLPPVCRSRAPYLPPPLFLPPSSCFTTLAPPPPASQLLVPPPPPLSSVAAPPPTASSHLATTHPICRSPSPPLPFSPLPTLPFPLCLSSPFFFSLPLSPLPLPSFPPFPSTYLPPSLSLPPFPSASPTLLPFTYLPACPLSLSCFCIFAFRETRSRLAASPLPLPPQPSQHRPSILPRVFPVSPYPPRPSSIAPPPSRPSSIAPSPRFFLASPHPLLPSFLASPPPFPAVVPNIAPSPFSVLPSIALLFLLLLSIIPSPSLLLSIAPSLFRPSQYRPPRLSPSSPRPSFLASPPPPVFPSSPASPPPSYPTSPHRVRVGSRLAGFETDLVANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9W2</accession>
    <name>A0A423S9W2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004476">
        <property type="protein sequence ID" value="ROT60948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9W2"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="469" mass="50576" checksum="FA3FDE74523D6E7B" modified="2019-05-08" version="1">MGQGQPPKFQCVENGFFADYYRNCMIFYSCDNGVKTTRGHRGKGPQKGASRERDLTRRGIEGKGPHRKEHRGKGTSHEGASRERDLTGGGIEERDHRKGIEGKDPHTKGHRGKGLTGRSIEGKGPHTKGHRGKGTSQEGASRERDLTRRGIEGKGPHRKGHRGKGPHTKGASRERDLTEGASGKGPHTKGHRGKGTSQEGASRERDLTGRGIKGKAFEGASRERDLTRRGIKGKGPHRKGHQGKGTSQEGASRERDLTRSRKGEIKGKDLTGRGIKERDLTGRGIEGKGPHRKGHQGKGTSQEGASRERDLTGRGIEGKGPHRKGHPGRGTSKEGASASRSSGKSFCSSSHRHRAAVAKIGRSIIGRIVGGWITIRGIRIRGRRNRKRDLTGRGIKGKGPHTKGHQGKGTQQGASRKGASRRAIEGKGPLTKGHQGKGTSQEGSSRKKDLTGRSIKGKGPHRKGRHRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAP7</accession>
    <name>A0A423SAP7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004263">
        <property type="protein sequence ID" value="ROT61288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAP7"/>
    <dbReference type="OrthoDB" id="6371339at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="28"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="302" mass="34411" checksum="FF3E5EA0367DB933" modified="2019-05-08" version="1">MQMVRAALYSLSAQEGSRERAEMQCRPPPSGPLELVSADLMDLRASVGGYRYVLSIVDHHSRYLQLVPLRNKTAETVLRGFYDHFITLFWTTRQIMTDNGGEFANEQWQEVCRQLEIRCSFTIAYHPSSNGLVERTNRVVKDALAMLVADKPGRWPLYLTSVRLAINSAIHRSVGDQPLYLLTGKMALFPRGLTNQVTTDTNLRVQQLAKARQLAIAASLRSREANAQAHNRKVRSTWQPEEGALVLRRDFTGGALQDRWQGPCRVIKQIGPVVFEVKDLQPPYRIVKQHRDQLKMYLLLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAV9</accession>
    <name>A0A423SAV9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004209">
        <property type="protein sequence ID" value="ROT61350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAV9"/>
    <dbReference type="STRING" id="6689.A0A423SAV9"/>
    <dbReference type="OrthoDB" id="10259057at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017156">
        <property type="term" value="P:calcium-ion regulated exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF234">
        <property type="entry name" value="SYNAPTOTAGMIN-15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="380"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="530" mass="58295" checksum="6CCD8CF7BD3C32E5" modified="2019-05-08" version="1">MPLNEIEALLSRCHLLSVLPDERRYLQTKQKKKTCNPVFDEHFGFHIPLRCVSERSLRVSVFDGGRHKRQAAIGHVIYPLAQVPADSAAAVAASNGSTTNNIIVRDLSREDETVPNNDLGEILVSLTFNDNLHRLSITVFQAKGIKVRLPPSLTPTPSPLLPLCNTNAPFPRPLLPHSFSNSSPTPSSTPSHLHPPHFYPQLLPHTLPHTLSSTPSTMQHKHPPSPPPSPPRPPFPLTLPMQHKHPPSPLPSLPCPPPPSPLPHILAHPFPPHPPHATQTPTLTPSLTFLAHPLPRPPSPSPPPPPFPSPPHPCNPYSPLPPPLPHPTPHRHPYPPPPHPFPLAPPSPLPPRPPPRNPTHPFPPRPPPPHATLLSPFPHPLAPMQPLLTPFPLPPPPRPPHTTPTHPLPFPAQVNEGEVVSWVKVSLMNQRRAVKTKKTAVVAANDEPQYNESFHFRPPPALEGVHITLQLYVASSSNSKGQFESEVSGRLVGRVTIGSFMFARGRALNHWNEVLSTPKEPIQFWHSLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH52</accession>
    <name>A0A423SH52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tripeptidyl-peptidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018542</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003420">
        <property type="protein sequence ID" value="ROT63568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH52"/>
    <dbReference type="STRING" id="6689.A0A423SH52"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048384">
        <property type="entry name" value="TPPII_GBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048383">
        <property type="entry name" value="TPPII_Ig-like-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022229">
        <property type="entry name" value="TPPII_Ig-like-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046940">
        <property type="entry name" value="TPPII_Ig-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF14">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12580">
        <property type="entry name" value="TPPII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21316">
        <property type="entry name" value="TPPII_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21223">
        <property type="entry name" value="TPPII_Ig-like-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="4">
        <location>
            <begin position="36"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl-peptidase II first Ig-like" evidence="6">
        <location>
            <begin position="319"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl-peptidase II galactose-binding" evidence="7">
        <location>
            <begin position="456"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl peptidase II second Ig-like" evidence="5">
        <location>
            <begin position="580"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="827" mass="91286" checksum="7D55D344CD5F1754" modified="2019-05-08" version="1">MASTTEPLGEFPFWGLLPRKETGVVSLLSKNPNFDGRGTVIAIFDSGVDPGAPGLQVTTEGKVKVIDRIDASGAGDVDTSTVVEATDGVIAGLTGRKLKVPEAWVNPSGKFHIGVKSAYTLYPQRLRERIIKERKEKQWDPVHKILLAEAQRKLQLLENNKSNGSSNGASPNSLIDKMTKEDAETRVSLLNSLEKKYNDLGPAYDCVLYHDGDVWRACIDTSERGELESGIHLGEYRITHQWASLTSADQYNISVNVHNDGNILEIVGMCSSHGTHVASIASANFPDAPERNGVAPGAQIVDRAVEHMLQHCNSIEDKVRFMVECGSERKKGIHLRNWLADKPVDMSVTVEPVLLDDTRADANQKLSFCMEMVLTTNAPWIRSPSCLQMSYTARSFQVSIDPRGLERGRVYFASVKAYNASNVEKGIMFEVPITIVVPVIDLLHGYKYTCPAEVFRAGCVRRHFLYVPVESTWATVTLKSSHSEKCQRFTLHAVQLKPDCSVKTIEFYKVVNLGCNESSTFVLGVRGGYALEVCLARWWSSLVDGQVEIDVEFHSLRPSHEEVTLFCSDGVQRVDVRAGLRPEEVSPQAYLKHHTQVLTPTESKVEVLGGLRDTIPGGRPVYQLILSYNLSVSKAAEVTPKCALLSDVLYESAFESQLWMLFDHNKQLLGSGDAYCTKYSLKLEKGEYTIRLHVRHERPDLLEKLSDLPLTVLTKLSQEVKLDVFTSFNAAVTCGKKAQSLSLGTGAVQPLYLTAPSLTDKTLKGLGLTPGQALLGTLSFAKDEQVRKAVSNHKFGPIRTMPVRAQACPLSNNFPCPPTPLPSFIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHC6</accession>
    <name>A0A423SHC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003408">
        <property type="protein sequence ID" value="ROT63626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHC6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="49958" checksum="49341326F6A76514" modified="2019-05-08" version="1">MPLCQRAINLIVGAARAFGSIRRLEINKLLSRTLQTAWPRESSAMPVAPTPCAWVLLGNALLSSSSPRWSSAIPASSPPSARGVELSSLLSPPFPSLFLPYPLFPPLPLFPSPPTPFPLPPLFFLIFSLPLPPFSPLSSHFLFATSSSLFFFFSFLHSFLLLLFSLLLFLFLSSLSFFLLSRRLSSPFSFRFLNLLFIIFLASFTPCSSFFPFSPFYHYLPSPSSSFLAASLFPPSHSLVLTSSSSFFFSFLYSFLLLFPSSFCPYLPLSIFLLSRRLSFPFLISSLSFFFFSFLHSLSPSSFCPYLLSPSSSFLAPSPHPLLIPSSLPPLQHIFLAFFIPLFSFSLLFVLIFPSPTSSFLAPSHSLSSLPSFLLVLSLSSLSLSSSLAPLLTPHPLNSSSLPLPPFSPPLPTPQFLIFSLPSSSFLAPSPHPQFLSHVPQRLPRNELKRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI22</accession>
    <name>A0A423SI22_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003375">
        <property type="protein sequence ID" value="ROT63815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI22"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019063614" evidence="2">
        <location>
            <begin position="20"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="58989" checksum="1F21B0F4D09FC0A7" modified="2019-05-08" version="1">MYILTFSLLFLPFHLFISSHPPDLSFPSFLPSLSPSSPPSPSPPSLSHLPPSLLLTLSSPSSPSLSLLPSLPLLCSLFFVYILCVSGPSLSLPPSFPPLPASFFPPSLSLPPSFPPSPSLLLSHPPLPPTLLSPSFHPPSPLPLSSFPPSFSSLLFSYPLLSSHPLPLHSLLPTHPLPLPPSLSPPLPPTPSLPYQPLSLLPFPPSIPPSLCSLFFVYILCVSGPSLSLPPFLPSPLPPFLSLPSSSPLLLPPSPPFFPRPSPTLSFPTYPPSPLPTHPIPPSNPPSPLPLPIPHSLLPSLSLSHPPLCVAFSSCIYCGVSGPSLSLLLPFLPLPPFFFPNPPFPPFLSHPPLPISFPPSLCLSSLLSPILASLPLPLLLPFSLSHHPRSSPLPPFPTFPHPCSHPIPLPSLLLSALPILLFCVAFSSCIYCVFRDPPSPSLIPFLLSLPSSFPPSFLPSSPSLSFPPPFPLLPFPPPLPASLPTPSPLPSLFPTFPFHPTPPPHPSPPFPPTSPSPSLSSTHPPFPSPPSPPSLCSLFFVYIFVRLGGPVSGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI70</accession>
    <name>A0A423SI70_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003362">
        <property type="protein sequence ID" value="ROT63865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI70"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="461"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="580"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="599" mass="65043" checksum="0240A6A2708C494A" modified="2019-05-08" version="1">MIRGGAPSRLSPALLSLSLSLSLSLSPLSPLLFLLFSLLSLSLALLSPLPFSCASLSLLPPCFSCFSLSLLSPLLSFSCSSLSLLSLALLSLLLPPCFSCSSLSSPFLLRRSLSSPLPSSPAILLLFSLLSPPLGFLSCCSLSPYLSLLLFSCLSLLLLENSILFFFSLPSRSLLPLPLPFSLPFLCLAFLSFDSLAIFSSLPFSCSSLSPSLPFLRFSCPSLSPTLLFPSLSLFLLSRFPFPCLSLSLYFPFSCSSLFPSLPLLSLVLSCVFSIFCSLTPLLCSSLFPLSCVSLLSFFSFLPFPSLLRFAFSFPLSVSLVSPAFAPFSSNYPVLLFPFLLPFPLLLIMLSSPISPILHPSLSSPLLFSSFPRSLTFLLFSCYLQITHTPFPSSLPSLLLSLTLLSLSSLSLGFFLSPYPPFSIPLFPLFPFSFLLPFSLLPFSCFLPLPLSPIRQSSLPFLPFSFLLPFHLSPAFLLLSSSPHIPHSLFLSSLSSPSPFSYPSISLLPFSCFLPLPISPIRQSSLPFLPLLLSLTLLSLSSLSLAFSLSPYHPFSIPLFPSFPFSFLLSSSSLSPSPTLSLYTTILNLLSIVLKYILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJJ1</accession>
    <name>A0A423SJJ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative major facilitator superfamily domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017747</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003273">
        <property type="protein sequence ID" value="ROT64313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJJ1"/>
    <dbReference type="STRING" id="6689.A0A423SJJ1"/>
    <dbReference type="OrthoDB" id="370281at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="605"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="637"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="775"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="805"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="127"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="138"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="851" mass="92821" checksum="87469559465E2D14" modified="2019-05-08" version="1">MGGTFGKHGSWVVDHSMDDIPLDFMNGGTRHGSIATITAGPHPPPNTSSSTSSCSHTSTFILNPPSHLISSISYLDLQPGLILHLILVLSTSFTTSPSTYFSNLRLNLRPNLPLTLDLIPLPNLTSTSIPPHPRDPPHSSTLTSTSFSTSPSTSFPTSPSTPTFTPPSFSTSPLEPPFPTSPSTPTSTSTSSHLTSTSSLPTSSPRPFLFHLTLTSFHLHSPTSLTSSYLTNPFPTSTLDLLSHLTLHSHLTLDLLSHLTLDLLSHLTLDLHSYLILHSHLTLDLHLNPSSFNLTLDLFSTSTLDLLPQLTLHSHFTPASTSPFEPPPRRDNTPDEYSLVLETAAERKARKRSHWVAYTTMFVMSIGFSIVLSGVWPYLHELEPSLEKGLSVGFACITTVLVFILGNGMYSMLHLFQGMGYLSCFYAMIVSRFIVGISSANVTLCRSLPGWFDNPKGEDSWDCNHCSCTGSGLRRGASLSLPPPFPSGIQTIVTIAIPEPVDTGVDWFVWDKFTAAGWTAALLGLINLILLLPCIFQEYNIAEKERAMMNAGRKDQALRLPKPDYVSLTAILFGFFITLFIYVLLETLAEPFMVDQYGWTDDKAMVVVGIALSGGGFLSIFMFVLSGVLSKKYDERLVMLVVGFVPLMVGTFLFLPWGPGTIPIQVCRNETMNLTTTVDMTTSTTIGTPPASLLEGDLVDTWHFGDINLLETEAGGLTCTPGCPEKQHWCENTPQLPIPQLIVAYIIVILGYPVAQSLGQALFSKILGPKPQGLWMGVLTGVGSFSRIMGPIFVSYVYTNLGTRWTFGILTVSMVLAEVVLMAVFPRLVPMKVPTLEELRGYDGPAASEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK71</accession>
    <name>A0A423SK71_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 31 TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017493</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003233">
        <property type="protein sequence ID" value="ROT64559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK71"/>
    <dbReference type="STRING" id="6689.A0A423SK71"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="4">
        <location>
            <begin position="126"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="4">
        <location>
            <begin position="168"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="242" mass="27432" checksum="567179C11DA60D69" modified="2019-05-08" version="1">MFARDQPPGNVSWVEEVERGCGGCVDGDVGKRVWMWMWVMDVEVDNGMWGMVGENLYGVHPMYLVVEENGSSHAVLWLNSNAMEAETMPLPGLTLRSIGGIIDLFFFLGPTPEQVVAQYTSVIGRPFLPPYWSLGFQLCRYGYNSLENLTSAVSRTRRHGIPQLPAGEYPVHEAGVANDVYITWPEGEAPDENFGAGDVMLGYVWPDNRTAFPDFFRQKTRDWWTEQIVDFHKTLEFDGLWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN36</accession>
    <name>A0A423SN36_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fibrinogen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003063">
        <property type="protein sequence ID" value="ROT65647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN36"/>
    <dbReference type="OrthoDB" id="6145874at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.215.10:FF:000001">
        <property type="entry name" value="Tenascin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020837">
        <property type="entry name" value="Fibrinogen_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF424">
        <property type="entry name" value="FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00514">
        <property type="entry name" value="FIBRINOGEN_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00053344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="294" mass="33756" checksum="A13CF2931F5962E9" modified="2019-05-08" version="1">MPLLSGSFHVGTSCHDIQSTQGATKSGIYLIHPPNLVQGPWKVFCDLESEGGGWTVFQVRDDVEPHENFMRGWEDYKVGFGDFDREFWLGNILLWSLTNVDNETNYELHIELEDWSGNKRFARYRGFRVGSERDAYRLYHANVYFGNAGDSLYSHNGLPFSTFDVDNDNRDGDFVERSCSRLYKGAWWYGNCHDANLNGWYLGGPHRSFADGVNWYTWTGYNYSLKRTVMKFRPQSSGPIPVGFDTFIIANRRRRMDDPFSEEKATPAGETGRLDVPEMMSSRNTLTRLDAGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRX6</accession>
    <name>A0A423SRX6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002874">
        <property type="protein sequence ID" value="ROT66947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRX6"/>
    <dbReference type="STRING" id="6689.A0A423SRX6"/>
    <dbReference type="OrthoDB" id="6374606at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054465">
        <property type="entry name" value="Integrase_p58-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22938">
        <property type="entry name" value="Integrase_p58_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="140"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="50231" checksum="C19530723F171F78" modified="2019-05-08" version="1">MSTTGAEGGTAKGLGHRTSSAVDGRQSGSSKLGSLATKNHWHEWDALKMKDGVLHRKWVKADGCVKFWQVVLPKELRARLIQEVHDGVANGHIGNSKTLSRLRQGFGMRKDVREWCKTCATCNAKKGPAKKGKAPLQLYQVGTPMERVAVDVTGPFPAIAAGNRFILVAMDYFTKWPEAYPITNHEAVTVAEVLVNQFFSRFGVSGELHSDQGREFEAAVFRECCQLMGIRKTRTTPLRPQSDGIVERFHRTIVQELAEYCSEGQTEWDRKLPLLLMAYRSAEHEATTFTPARMMLGRELRFPLDLVTGRPPYEEFPVASSDYAVELQQRLEEVHHQVRGHLKCAGESMRRYYNRDARAVKFKVRDLVWLYNPQKKGMSPKLQSPWEVPYTIIEYGTEVTFRVRRRPGARARVVHGDRLWSIIEMATTPGAPAWRKLKTHARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423ST72</accession>
    <name>A0A423ST72_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002814">
        <property type="protein sequence ID" value="ROT67396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423ST72"/>
    <dbReference type="STRING" id="6689.A0A423ST72"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="486" mass="53697" checksum="4E8888E401ADDA9D" modified="2019-05-08" version="1">MGTSNFYSPQPHNPSRKQIFPRSPFLLLSLPFPLDIFLSLCLSPLPSPFLDPQSLMPVAPSPPPHPPFLPLRVIFPTPLPFYFPSPTLYSAPLISNLFPRSLSFHPFPSSPFYYNSPLWQFLFSPLTQNYSFTPPPTPSPSISPPQHSFSSPTLSLFPYPALLVELHLCCPPFVHPFPSPPFLSPPLVLSLLIADPNPYLPSPSSPPLPLSFPCSCLFFYPLTFLSNKFPSLTSPYSPLPSTSPFSLFTPPPFPFFLPLLALPAHNPTLTPRPIPTPTPPPPLPTPPTPLPTIPSPFLSSPTVLAPQPQTNSTTYPHPPTSTPPLPHAPSSHPHHPYHPPPPPPSHPRPILTPHHPYHPPPTPHPTPIPREPQRCVSGDRTPTLILIVPNLHNSAQIGAATLNAYWKDASDLRDTSILGIANGRSLRVPHKNTKQNRSLTRNSPQHRLVRHATQRIRPQAEATRRKYEAEPTATRPIGVISHRART</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STQ6</accession>
    <name>A0A423STQ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002799">
        <property type="protein sequence ID" value="ROT67569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STQ6"/>
    <dbReference type="OrthoDB" id="1915375at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031985">
        <property type="entry name" value="DUF4787"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35455:SF1">
        <property type="entry name" value="AGAP005842-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35455">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16029">
        <property type="entry name" value="DUF4787"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="142" mass="16127" checksum="833E00C28BF5C85F" modified="2019-05-08" version="1">MAETGTAEVVNSRTKCWREMVGEVWSVLVAASTVTWIAAVLGMLRVTEAHANTVTYTFTQFPYKESVANEKLWSEYEVACAQSPRCLELRGVQHTRCVRQCVSPSCYLDIYTHDELEEGEIDVRLSSFKGCFLQRMSGHRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUV6</accession>
    <name>A0A423SUV6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium-and chloride-dependent glycine transporter 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_013939</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002736">
        <property type="protein sequence ID" value="ROT67958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUV6"/>
    <dbReference type="STRING" id="6689.A0A423SUV6"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF236">
        <property type="entry name" value="TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT67958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="269" mass="30156" checksum="E248850FD38734D9" modified="2019-05-08" version="1">MAHDLGVDIEDVAASGPGLAFIAYPEAISRTLPFPQLWASLFFFMLFTLGLDSEFALLETVLTALYDTFPSTRNQKFKLTALLCVSCFLMGIPMCATMGQYIFYLVDSFGGGVGVLLIAIFELVGLHWVYGVRRFSEDLKFMLGYNPSMFWKVCWVFIAPVTLILMFIYSAVTWTNPKYGDVEYPDWAIGIGWFLAAVSVAMIPLVFVLVLLKKLFTGDIRRVFSPASNWGPGDPEARQELLALKHGLNMSETKFGIDNPAMDPRYYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY36</accession>
    <name>A0A423SY36_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002599">
        <property type="protein sequence ID" value="ROT69137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY36"/>
    <dbReference type="OrthoDB" id="6361686at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="28492" checksum="2617246245A30B63" modified="2019-05-08" version="1">MLESGRCFLLRIFCRAAKKSALVSRPGRVLCPPPLPLSLPPLSLPIALPFRPLSLPSPISPSAPPPFPSSSSTHPLSAPLLPSLYLPIPLPASLSSASPHLPVLSPALFGATMQVRLSTTPRAQALLLLLPLVLLAARANAQAEEAPSAAPEPPARHRSATFIPNVFPDEEVETDVPSADENTIGQSPCPRGESGAACRQELASSTFNCTTDSCMQCRDECSTMEPSLWPLCCRDHFLCCRPLASACQQCDTPELFPFCGATFKRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T378</accession>
    <name>A0A423T378_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras-like protein Rab-2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002364">
        <property type="protein sequence ID" value="ROT70982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T378"/>
    <dbReference type="STRING" id="6689.A0A423T378"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="201" mass="22189" checksum="52707831C674CF23" modified="2019-05-08" version="1">MSHISVNFLVVGDTGVGKSSIIASFFGEKIQPIHLPTHVLSASHCTFAFSSKEVEAYICDLPGSEHFRPIVSCFYPGAAAILLVFDLINKHTFNNLPRWMHDIRETLPAHSVVVLIGNKSDLEKARVVSRAEAQIFADRFHLRYFEVSAALGLNVGLAFDVAAGLVLDKVEERDGATSEEDKAVSSCDMGEEERLIWKKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3R6</accession>
    <name>A0A423T3R6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative Golgi reassembly-stacking protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010534</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GORASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002336">
        <property type="protein sequence ID" value="ROT71147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3R6"/>
    <dbReference type="STRING" id="6689.A0A423T3R6"/>
    <dbReference type="OrthoDB" id="3318at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000026">
        <property type="entry name" value="Golgi reassembly stacking protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000056">
        <property type="entry name" value="Golgi reassembly-stacking protein 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0519">Myristate</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="10">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="10">
        <location>
            <begin position="111"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR607583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT71147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="46350" checksum="F2BBAB98E8FA6450" modified="2019-05-08" version="1">MGGSHSVEIPGGGMEGYHVLRVQENSPGQLAGLEAFFDFIVAIGNTRLDQDNDTLKELLKSSIEKELKMTVYSSKTQTLRTVSITPSNLWGGQGLLGVSIRFCSFEGANENVWHILEVEPNSPADIAGLQAYTDYIIGADSVLHESEDLFSLIEAHEGRPLKLYVYNVDTDACREVTVTPDTQWEGLEAWDVGLATDIFIAFLPSVMCPKHHSPLNQSLFLHHQNHCYRWPLEAYTTSFTIHSNSYSPPAELPASVTSPVVPAPTPYSQAPIATTSYAPVQAPVETPIPNPASIASPLQTPMQPPMQVSTEIPMQPMNFQPSPMPQPSPLMMGGAPTVPVMAPPVIGGSEVLLITTYGHPPVPPTFAAPSMPSIPGMPVTTPINLPGMPPITVSATLPPESFQGILATHLPLLSHNQFSRLLTNPLSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCC0</accession>
    <name>A0A423TCC0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001936">
        <property type="protein sequence ID" value="ROT74095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCC0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="47167" checksum="BB4F218EC60912A5" modified="2019-05-08" version="1">MRTESQPFPHVSSRSSLAQEVHTCCGTRVTLYRLIHALLFGKFRVPFIPSPLLSSSYLYRGILWVIGLLSLFLVLLPLLSLLSSAVSPPPTLLSISLSLSLPSLRHPLVCSSSLSFSSSFLNLRFVCIFFLRSLGPLRLLCPLSPFLLFRRIRPSSYLSFFSPSRVGSVLHLLFFVLSCFTCIRLVSMFAPASLLLAMAPRRTPFHPAHGPALSSSDLNSDARNRSSSYPAAGIDIDRFAVLPCSRLDDQDQSTTHGILRRALVGTSVVSSPISRDFAFSAPIGIFLRPRPVSTLSSVSSLTSRQSLSQLSQSDICALPVIPVIIPIRVRSSPPVCIHNSHWSGASRSFRSGPSIEASFLVLGHALLVFHTYVPVSRFLSGLLRVHVHAYGYWSAPSRNLEFYSLPSPADTPRMTSLRLLISACYASSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCI7</accession>
    <name>A0A423TCI7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001936">
        <property type="protein sequence ID" value="ROT74097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCI7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="469" mass="52715" checksum="47060194877B8515" modified="2019-05-08" version="1">MKPKDRTPTKQRGKRSETETNAATDTENEKVRDAFLGPLLHGLIARGKLQTRDEQAKKVMQFSPSLQERAETVWLSRITVCYFSSFHNIFFHLISPFFLEIHPFVYTSFSLPYFLPPLALSSTHHLIPLLPIPPPIPSLLNLLLLSLPLLFSHPYPHFPSHPFLNSLPIPSLSITPFLLLHRYLFLLLCSLSFLHSNFSYNPSSFSTFFYPFASPLLSLLLFSFLIICLSPHTFLSRLTPPLFLSSSLPLPLSLLLPLFSFSLIITLLNPDNPLTPFPSSHHPTSLPSLSSHSSLLPYIPLTLFLPSPIPTPPLLSSLPFLPPSHFPSPSPFFLLFPSLSPSFYPPFPFLPSLFPPIPFPLFQTFPFPFFPITSLTLLHTPSPSYLFPLPTHPFPFLPHPNPSPALAHLCIIHKQTTKGNKRPPLLNKIVYKKCAGFIEFDSPSAIVFTGFDTILRESNNISKTNVDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TD70</accession>
    <name>A0A423TD70_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001899">
        <property type="protein sequence ID" value="ROT74428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TD70"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="604" mass="64405" checksum="169309206D607EE3" modified="2019-05-08" version="1" fragment="single">SPLTNPALPHPQPPYPAQPPHPNHPLPCPTTSPSTTLPLPYCLTLHLPCQATSPPPYPAPHTLNNPTPYCLTLNPVLPLHLTSTTLPCLLPPPPCSTQPPTSSSTTLPTLYLTSTLPCPAISPSTLPCPVVALPPYPALLSHPPLIYPQPYPAPAHVALHPTLPLTLYPAPPSPYPALATCPPSTLPCLTSPSTLASQSPSTLCQHVASTSPSTYPSSTSTLPCPATSPPPYPQPRRLHPTLPSHVALPPYPAQPRRPPPYLPSHVALHPTLPTTLHPYLPATSPSTLPCPPRRAQPPSTLPLPSHVASTLPPQPRRPPPTLPSHVALHPTLPSTSPYYLPSHVALHPPCPATSPSTLPRRPTATLHPTLPSHVALHPTLPSHVALHTYLPSTFALPYPAPRRPAQPRRPPPYPPSHRPASHVALHPTLPSHVALPTLPSTSLRPCPATSLHPTPAQPRPPPPAQPRRPPPASHVALHPTLPSHVASTLPCQPSTHLPATSPSTPSTSPSTYPHLHPTLPLPHPQPLCPALPPRPPPYPAQPRRLHPACPSTHPLTSHPTLLSHPPPCPTQPRRPPPLPDRSTWIPRSPWRSTRPASPCCRRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDA5</accession>
    <name>A0A423TDA5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001898">
        <property type="protein sequence ID" value="ROT74435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDA5"/>
    <dbReference type="OrthoDB" id="6343044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="453" mass="51622" checksum="C39AC3285774464F" modified="2019-05-08" version="1">METQGKWLWKKTETEKFYEPFAISYQLTIVTREPLLEEQVIRALTHCQRKVPILKTCFGERDGDIWIREMTQEIIDYELLPDDTKDADLHDKIQQYSFNKETGPLWCVKLKPEFNVSPDAVFGEGVAGFPHRYSLFLGINHAVTDGTSNVIVCGFIVQILDDILAGKEINDEEQLGIYISDEKTKKAIEEQVALVKGNPELQSKLVADWQVLQGRRSLLKTVFKGVGEEKGRSLYRTQNLDAKTTAAFIKRCRAEGITVNSAFAAIANFTVVDLLVHGGFERDSYSIRSTHVVNARRYLEGDTSQYLGCHIMLLNPIFETPRNFSENFWNSAKSIHEEIHSKIKSGYPLQLEGVSDLVSKTPYCNPIFEFEYTTTNMGDITQKITEGGDHVQVLHLLRTADLCKVPCTCNNFIHTLRGHLTHTIVHNSAYFTPHMAEMFCEKVFHYLRACLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDN0</accession>
    <name>A0A423TDN0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CUB-serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006925</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001877">
        <property type="protein sequence ID" value="ROT74590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDN0"/>
    <dbReference type="OrthoDB" id="6358852at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="3">
        <location>
            <begin position="102"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="237"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT74590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="47194" checksum="96ECB6C165C389DC" modified="2019-05-08" version="1">MIPLALQCAWSDASARIAPKSRGVKLGTVPLAVRHRLTQWCVGPRQVTLNPGQAQTYPSGGVGPRQVTLNPGQAQTYPSGGVGPRQVTLNPGQAQTYPSGGVGPRMAPHFENRGSSKTFQSKNYPNNYPGGKKCTWKFRTSTDSKLSIECDDFQLQHSKNCKKISSAYCGVKGSLTVSDKSSKVTVLFKTNKKKSNTGFSCSVRASVPDSQTTTVDPEPTSECTGCGQVNRANRIVGGEETEMHFSIPYYYCSMTTSDYVLVGDHNLYSASEANSQWMEIAEIVNHPSYDSNTLDNDIALIRLKTEIQFPSDNKIAPVCLPTAGEMYDSVDATITGWGAQQEGGETLVDQWWWKKTASGSWWELCRGVMAVLDLIGPESMPELHNICNGFLTHKPESVSMEHTCSYKCPDDCPYNCPDACPYYCTHACPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDZ4</accession>
    <name>A0A423TDZ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytosol aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.1</ecNumber>
            <ecNumber evidence="5">3.4.11.5</ecNumber>
            <ecNumber evidence="11">3.4.13.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cysteinylglycine-S-conjugate dipeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Leucine aminopeptidase 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Leucyl aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Proline aminopeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Prolyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C7M84_006856</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="22 23" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-cysteinylglycine + H2O = L-cysteine + glycine</text>
            <dbReference type="Rhea" id="RHEA:28783"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:28784"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>S-benzyl-L-cysteinylglycine + H2O = S-benzyl-L-cysteine + glycine</text>
            <dbReference type="Rhea" id="RHEA:62568"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:145802"/>
            <dbReference type="ChEBI" id="CHEBI:145803"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:62569"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an S-substituted L-cysteinylglycine + H2O = an S-substituted L-cysteine + glycine</text>
            <dbReference type="Rhea" id="RHEA:60444"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58717"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.13.23"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:60445"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="4"/>
    <dbReference type="EC" id="3.4.11.5" evidence="5"/>
    <dbReference type="EC" id="3.4.13.23" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01001869">
        <property type="protein sequence ID" value="ROT74631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TDZ4"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 22" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="21">
        <location>
            <begin position="1978"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="71"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="583"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="725"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="848"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="907"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="986"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1037"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1217"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1256"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="427"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="611"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="848"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="926"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="988"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="1152"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1163"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="1173"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1274"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="1389"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="1546"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="20">
        <location>
            <begin position="1642"/>
            <end position="1656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ROT74631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2138" mass="233143" checksum="D4BECDED969841F7" modified="2019-05-08" version="1">MKRLSPASSAFSNRTPKETTYPLVASRNRRPKGTTDSPRLPAPEIAPKGTYALFLVFGSLNQPPKERTALSLVFRFSKSPPEGPRQTSPSPRLSASSGNRPAPTTAPREEPHPSPRLGFSKNRPPPPAPREGPTPSHLRLGLLLNRPPPSRPEGTTPLSLVFDFLEKRPPLYRPTRRNTRPLPSSFASFSKSPSKDTTASSSSSASRNPAPTKEPQPLAQPLSSFASRKSPAEGTQRRSPQSFRFFNETRSLKEPQPLRRLRLLANRPPKESKPSSSYSASRNRPQPPPTHRSEPRRPLLWETIHAVSPRSGPSRNRPPKDSTPLLLSPSASREIRPPKETTPLSRPRLLKSPPEGNPTPLFSSSALRNWPQKETITPSFLVFGFSKSTPRRKPRLILLVFGFSNRPPPPPEGTTLPLLLIETPSLASSNTRGTTPSPRLRFSKSPPKEPRPLLVFGLLEIAPRRNHALSSSSLLEIRPRRNHALSSSSLLEIAPKEPRPLLVFGFSKSPPEGTTPPPLLVFGFSKSPPHPAPRGKPALSRLRLLEIAPEGTTPSLVFGFSKSPPKEPHPLLVFGFSKSPPKEPRPLLVFASRNRPRKGDKKSEDLRNNTSLSSSSAFSKSPPKGTTVPSSSSSASRNRPPKEHALSSSSASSKIAPRRNHTLSSSSASRNRPRRNHTSPRLRLLEIGHRRNHSPSSSSSASEIAPKTTPQSPARLRLLEIAAPKEPHASPSSSVLEIAPPPAPRRNHARLPRLRFSKSPAPPPLPPEGTTPLLVFGFSKSPPEGTTPSPRLRLLRNRARPKEPRPLLVFGFSEIAPKEHALSRLGFRNRPEGTPTLFVLRLLNRPEGTTTLSSSSASRIAPKGTTPSPRLRLLEIAPFGFSKNPHHPKEPRPLLVFGFLEIAPEGTRPLPRLNASRNRPRREPRPSFSFGFSKSPPTSRPNPSFSSRFLEIAPKEPHALSSSSLEIAPEGTTPSPRLRLLEIAPEGTTPSSSNFGFSKSPPEGTTPSPRLRLLEIAPKEPRPLLVFGFSPPKEPRPLLGLRFSKIAPPPRPPPPKEPRPRPRSSLLENRPQEGTTPSPRLRLLEIAPRRNQPSPRLRFSKIAPQRKEPRLSSSFASRNRPRRNHASLLVFGFSKSPPPPPPEGTTPSPRLRLLRNRPRRNHTLSSSSASRNRPPPPRPPEGTTPSPRLRLLEIAPEGTHTTLPRLRLLEIALAPEGTTPSPRLRLLEIAPPPPPEGTTPSLLVFGFSKSPPKEPRPLLVFGFSKSPRRNHTLSSSSASRKSPPEGTTPPSPSPRLRLLEIAPEGTTPSPRLRLLEIAPEGTTPLSSASRNRPRRVLPRISSPLLGFSKSPPKEPRPLLVFGFSKSPPKEPRPLLVFRFSKSPPKEPHAPLSSSSASRNRPRRNHALSSSSASRNRPRRNHALSSSFGFCEIAPEGTTPSPRLRLSRNRPRKEHAPLPRLRFSEIAPKEPRPSSSSLLEIAPPPPPEGTTPSPRLRLLEIAPRRNHASLSSSASLEIASPEGTTPSPRLRLLEIAPEGTTPSPRLRLLEKPPKEPRLSSPSASRNRPPKEPRPPRLRLSKSPPKEPALSSSRLPEIAPEGTTPSPRLRFEIAPEGTTPSPRLRLPKSPPKEPRLSSSSASRNRPRRNHTPSRRRTSRNGPLVVVCVGEGGGVVCVIDHRVWTHHSPLLQLRKSSLCAAADIGAVKKGKSRVLYGVSETFPVVAVVGLGPAEKTVDVLEERDEAKEAVRTAVAAGCRSLEEAGMSRIQVDPCGDAEAAAEGAHLATFKYQELKAKKKPVPTLECLLDRGAVLAEGQNVARRLMETPANILTPTNFAQEAVNNLEGLGVEVLVRGYEWAKERNMNAFLSVTRGSVEPPVFLELTYRGADYSEKPLAIVGKGVTFDTGGISLKPSANMDKMRADMGGAACTIGSLLVAASLRLPINIKGFIPLCENMPGSSATKPGDVVVASNGKSIQIDNTDAEGRLILADALHYASQHKPRAMIDMATLTGAMAVALGAGAAGVFSNSSILWQLMHRAGATTGDRVWRMPLWKHYSSQVTDFGLADVHNLGKYSRDGGSCTAASFLQEFVTCDHWMHLDIAGVMENKDEVPYLGKGMSGRPTRTVAHFAELLALGEGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TES5</accession>
    <name>A0A423TES5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001832">
        <property type="protein sequence ID" value="ROT74931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TES5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="23038" checksum="DB1736B07F6BFCE4" modified="2019-05-08" version="1">MIEGTAGAKGKGEQSSDAEAETCCSYTGKGYGIDCKVGGIGRQMFLMSEGISWRMWQSGGTKAVGLKLKLDFSFAWGKVGERRERSQFLGRCEIVLRSAARSVSHDLKDKDVVQGGKNEGAVPSAHENDSPGLNEGKALRVRAAYNGEVLKNYRFWTGKLHFSCPCSYNCIALRFRGRAADEATGVTPLEAALFALDDLSQASQRESVGIAVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFR6</accession>
    <name>A0A423TFR6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-lipopolysaccharide factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006173</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001790">
        <property type="protein sequence ID" value="ROT75296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFR6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024509">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038539">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11630">
        <property type="entry name" value="Anti-LPS-SCYG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0044">Antibiotic</keyword>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019165450" evidence="3">
        <location>
            <begin position="21"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="148" mass="16604" checksum="3CE03558C1E9A04E" modified="2019-05-08" version="1">MRPSVMITLLVLVLAAQCTARKKEKILKEADQQPLGHWMTKSVTFMGHSCKTEVELGFSHWTGYYQCTFSCDPWTDITGKASSPSKLVAAEECMQDFVNKAVNSNLISWTDIEKQGSWVVAVAGVTRRCESKCGSLQTQDIDDFQRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFS6</accession>
    <name>A0A423TFS6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[histone H4]-lysine(20) N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.361</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_006168</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60344"/>
            <dbReference type="Rhea" id="RHEA-COMP:15554"/>
            <dbReference type="Rhea" id="RHEA-COMP:15555"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="EC" id="2.1.1.361"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.361" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001790">
        <property type="protein sequence ID" value="ROT75291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFS6"/>
    <dbReference type="STRING" id="6689.A0A423TFS6"/>
    <dbReference type="OrthoDB" id="5560686at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140944">
        <property type="term" value="F:histone H4K20 monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043516">
        <property type="term" value="P:regulation of DNA damage response, signal transduction by p53 class mediator"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10528">
        <property type="entry name" value="SET_SETD8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051760">
        <property type="entry name" value="KMT5A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016858">
        <property type="entry name" value="KMT5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047266">
        <property type="entry name" value="KMT5A-like_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46167">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE KMT5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46167:SF1">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE KMT5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51571">
        <property type="entry name" value="SAM_MT43_PR_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="14">
        <location>
            <begin position="348"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="260"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="171"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT75291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="484" mass="52463" checksum="3C54BEFB8B6F1FD5" modified="2019-05-08" version="1">MVSHPTSQRNSSPRSSARGNMAKGKRRTDRSSKDENAVLSHLDGPKGPKDSRLEAKVVNGSLSNGKLGHTASTTQKETKITTYFSPSRSPPAADDAEGPRGETHGGDSCDMNPELSSAQLSRTHPSSAPSTPTKMMNGHAESANPVTAFTTPPKRTVCTRSQALKELQLQSSPTAPSSASVPSSPSQAGATATTPMGPSTPTSPTPASAGEDGSSPHTGPPTPHKIQALNEERLRLDSPLSPSSALSKLKLSLTPKKLTFNGKTTKARKKLPVQSNTTRTVTHAKPEKPAKSTTTTKTQANGEAKSNLRSTQMTEYFPIRRSERKPKTTLLQERQKAIEERIISGSEEGLTVKHFGAKGRGVITTRKFAKGEFVVEYIGDLIDMQEAKEREKIYAQDASKGCYNYYFTFQNQQYCIDATEESGYLGRLVNHSRNGNLVPKAVEVNGRPHLILLAKHDLEPSIELLYDYGDRSKEALEHHPWLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI60</accession>
    <name>A0A423TI60_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001689">
        <property type="protein sequence ID" value="ROT76142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI60"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="PKD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="231" mass="24962" checksum="0DB289C96E839E78" modified="2019-05-08" version="1">MPRPPPSSRALPSAPARGSADGRQHLHSRCRPSRRGGGGQGHSAGPSRTPALRAQSIVAERDVVLPLLPFGLREERTRNVSINISVAEGSHLDPLALELEEGVELFSRPDVDAQNGGGGWVAEFLCNWRRPGRYRPRVRVSNPLGSETVSLRTSILVQSIPQAVVLMRPVAEVGQEVVFHALSNGTDVRYDWTLPRGEVLRDAAASSFLPLKPITPITPPFLVTLPSPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI78</accession>
    <name>A0A423TI78_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleolar protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_005226</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI78"/>
    <dbReference type="STRING" id="6689.A0A423TI78"/>
    <dbReference type="OrthoDB" id="285729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019002">
        <property type="entry name" value="Ribosome_biogenesis_Nop16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243">
        <property type="entry name" value="HSPC111 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13243:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09420">
        <property type="entry name" value="Nop16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT76158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="24858" checksum="8E14F34CE01EB133" modified="2019-05-08" version="1">MRHHGDSDFARMGVRQRKKMRKQFRYETNRKREFNKGKKTKIDIEVIRKVWDKSKSTHTNMAQLGLEYKLNKIMPPNEMETDVQKKDIVDEGKQKAVVETLEGQVKNQVAKTKLPPRLTHSQRSYIRYMMQRHGTNYYAMSKDPKNYYQDTPKQLEAKIKSYMDNPRYYIPEMRKKGLLPAKLAEKKQKVQDKKKKAQKKKFNSKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKS2</accession>
    <name>A0A423TKS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001571">
        <property type="protein sequence ID" value="ROT77056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKS2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019415658" evidence="2">
        <location>
            <begin position="21"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="42935" checksum="32132D90237D3F19" modified="2019-05-08" version="1">MSVFLFLSLPILSLLSGSVSFLFFLSLPPSDSLCVWSGPCFFFSFDLSSCVPVRSVSFPLSDSSSVVSVGLSLSLFSPQILLFVSVCSVSFSPFSFHFSLWSVGLSLLFSLSDSLSWCLSVLSPFSSFFFLGFSLCLSVCLFLLFLILSLCLSVCPLSFVFPDSLLCLSVLSLSFFSSLPRFSLLSVGLSSFSFLLILSVSVGLSSSFFFSLPILSVSVGLSLSFFSSDSLCVCRSVSFFLFPISLPDSLCSVGSVSFFLFPILSVSVGLSLSFSFSLCVCLCSFSFPILSVSVGLSLSFFLFRFSLCLSVCLFLFFLFGFSLCLSVCLFSFPLFDSLCVCRSVSFLLFLSALVCRSASFFLLFPILSVSVGVSLSLFLSLPDFSLCLSVCLFLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLN4</accession>
    <name>A0A423TLN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Trypsin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_003974</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLN4"/>
    <dbReference type="STRING" id="6689.A0A423TLN4"/>
    <dbReference type="OrthoDB" id="6368789at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019240728" evidence="4">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="41"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT77359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="286" mass="29816" checksum="9361A11646783960" modified="2019-05-08" version="1">MASQTLLAVLTVAMMGAVSQAAPPHLNGSLPFVWQKAASRIVGGVTTGVNEWPWQAALMYSSQQFCGGSLINDRYVLTAAHCTEGMKAADLTIRLAEHRLSTSSETSVVSRSVSQIIEHPDYQPGERHSVASVHAATQPTYAGKTATVTGWGTTSSGGSSSDTLREVDVTVVANTACQSNSYGSAIKDTMLCAGSTGKDSCQGDSGGPLVFKDGGGNYDQIGVVSWGYGCGARGYPACTPASTATSTGSKPTQEMVFTAEECVCSLATPTLPRPPVRVVRKKANRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMX1</accession>
    <name>A0A423TMX1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001479">
        <property type="protein sequence ID" value="ROT77777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMX1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="527" mass="59707" checksum="66B723D0E6B04798" modified="2019-05-08" version="1">MGSIASKAFRRASSITVIIDVFRARASKRWRRGAILFLFIILSFSSSSSYILPVFSSPRLSSLLLSFTSFLFFPPTCFQFRLSLLSTLLHFHRFSSFPSSSSLLSLSFYFPYTLFYFFYIFSFLYISHIRFSTFSPIPLFPSIFRPFLSSFLSSSLLFFLFVSPLYSSFSLVPSIPSPTPFLSPSSLPFPSLSPFRVPSFLFVLSPLFPSSPFPFSLPPFFLHFIIPFPSSPILIPLSLPLFSFSALTLFPLSFYHPFPSPLFLCPLLAPLPVSSIPFIRSLRLLPLSLCFLHFPLPSFHLPLSFILVSPLFYFSSLPPFHFPPPLSFFPPPFPLSPIVVPPLPSFHFLFPSSRYLRVSSSPYLFSPLSSFPLSLFSSLLLFPSYSRVLLYPPLPPLSAFLLSPPPYPLFSFLLFPPLYHLFACPFSPYPLFSSLLFPPYSRILLYPPLPHPDYRVPSLLLFTPLPPLSSFLLSSLSPLFPHPSLSSSSPPYYRVPSLLLFIPYSLASPTTQDLSLLLTCFAWRQCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNS3</accession>
    <name>A0A423TNS3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynamin-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001430">
        <property type="protein sequence ID" value="ROT78106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNS3"/>
    <dbReference type="STRING" id="6689.A0A423TNS3"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GED" evidence="2">
        <location>
            <begin position="126"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="23750" checksum="8FEC623129090C27" modified="2019-05-08" version="1">MTRFMGEQGLPRPALPLEPAASAANKDGGANNQNWFSSLIAGPRAETTAPSKEQSRESSPSATPTHQQLALSAFDTIINPDQGVEVGKVPTPPEGGILSPQKPVNLLPEVPMQQTRKLTERESKDCEVIERLIKTYFYIVRKSIQDKVPKAIMHFLVNHVKDNLQSELVKHLYRTEEIDTFLSESPEIAQRRKEAAEMLKALQNANVHYWGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TP43</accession>
    <name>A0A423TP43_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD-dependent protein deacylase</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Regulatory protein SIR2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003054</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sirtuin family. Class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001410">
        <property type="protein sequence ID" value="ROT78235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TP43"/>
    <dbReference type="STRING" id="6689.A0A423TP43"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01409">
        <property type="entry name" value="SIRT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01967">
        <property type="entry name" value="Sirtuin_ClassII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026587">
        <property type="entry name" value="Sirtuin_class_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003738">
        <property type="entry name" value="PRK05333.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="97"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="214"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="240"/>
            <end position="242"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT78235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="30177" checksum="73FB77ECC6E96686" modified="2019-05-08" version="1">MQEFVDNHRKIFVLTGAGISTESGIPDYRSEGVGLYATSNKRPVQFKTFMDSAKARQSYWARNYIGWPRFSTFQPNITHLTLAEWEKKGKIQCVVTQNVDRLHHKAGSTKVHELHGTAFNVICMSCSKMVDRHSFQSRLRILNPHMSSHSSEIRPDGDVELTEEEVNQFQVPPCKHCGGIMKPYIVFFGDNVPKDRVERVKQELSESDGLLVLGSSLFVYSGYRFILQAVDMGIPLCAVNIGTTRADKHLDFRISARCGEVLPQIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRE8</accession>
    <name>A0A423TRE8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001301">
        <property type="protein sequence ID" value="ROT79030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRE8"/>
    <dbReference type="STRING" id="6689.A0A423TRE8"/>
    <dbReference type="OrthoDB" id="6381127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="33"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="140" mass="15908" checksum="56CD843EC3532C48" modified="2019-05-08" version="1">MRRDVQERCRTCEVYCARNGPVKKNRAPLQLYQVGAPLERVAVDIVGPFPVTTQGNRFICVVMDYFTKWPEAYVLPDHEAETVAEALVSNFITRFGVPCELHSDQGREFESVVFQECCRLLGIKKTRTTALRPQSDGLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRH8</accession>
    <name>A0A423TRH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001295">
        <property type="protein sequence ID" value="ROT79057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRH8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="48349" checksum="F949CBCA11ED6F17" modified="2019-05-08" version="1">MGVREGGQGRGKGGQMSRTQHVARNEGHVRSGRGQSTEWAWSQEADGEPDASISRLEMLRDALGTRPRETAAAGLEQTYDTAIHPIIFSSSPFPRPYYRLFSPPPCPYYRLFPSFPPYYRASPLTAFPLPSPPGPLPLLFPSPSLSLLPAPCPYSSPFPTSLGFPLPSPPSSTRFSSPFPPLPPCTGVSSPFPPPLTSPFPPSPTIGVSLPSPLSHGVPTTRVSSPFPPSLTTGVLSFPPSQYRLSSPFPPCPYYRLFLSLPPLSYYRRFLSFPLSLLPAFLSLPPLPVSLHPSYYRVSSPFPTTTLQSFPPPTTRLLPAFLSPSPLSYYAFPSPPLLLPGRRLPVYPHAAAAKTPRAPCRGVLALLTRNPPPPPTRFRGAAAGARSSEPFPRPSRERQESSRLSHGRRPVLGVVMRTRPDTSWRHNLHLMPPRPPSPAAAVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT50</accession>
    <name>A0A423TT50_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001213">
        <property type="protein sequence ID" value="ROT79634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT50"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="40879" checksum="3C00FA855C87B626" modified="2019-05-08" version="1">MPLSTSSFLLLSLSSSLLLLSPFLSSLSSFLLISPSLSFFLLSLASLFILCLFLSLFFLLLFLSSFLLIPLSLSFSSMPNIPIEPVLTRLNDFRYANDPRPQELNAIVALNPCGHAAFGAELQDVLLAPDVERHEDVLGAELEVRHEPRHQDRARRACSAQGVGSSPHASGDMTDSESALADGLADPPGLDADRNRPLQLLSAMPLLGEFFITAALLLLTGVVWRPRLFRLPPKAPRPPGAIQGAELNPELLLDLEGVASAFSYGDADVFGKDLHWEDHALLEHVLQDELLQLLDGPAHIGGQARYDDGRFPVLGNVNPDAVLFPYVTDAGAALADGLAVVRWRDVRGSAFRVADLSFDVRELFEHQRTVLFLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY36</accession>
    <name>A0A423TY36_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000994">
        <property type="protein sequence ID" value="ROT81292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY36"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="53180" checksum="2957AA45DE928756" modified="2019-05-08" version="1">MEGLCRFALSSPFFPPLYLLPPESPFSSPPFSLFRFWVSPILIFLLSTLFWFLFHSLFLFVRSASSFLFDYSFPLLFRSFFLFLFSLDLHLLPSALPPSFFLLSFSALHLLSPPLPPTNPSSLSLSPSPFPLSSPSKFLPTIPFPLPPSSSLFSIPFPSSISFPLFSPLLLPLSLLSKVFTSIFPHHSSPRFSILPLILLFSLLHSPSHPFLLSSLSSPLFICYPPLSFPRLSVSPLPPPPFLLPSHSPVPSPPPTLPTTLPSPSLPLSSPPLPPLHRFLPLPLLYYSSPLPLFPPLPISTRPSLSFSPPSSLLPSLSPLSLPPPLPSRFSTTPPPSHSPLHTSPFPPSLPPPLPLRTLPPLLHPSPSHPPSLLPFPSPLPLPSPLSLHPTLSPPATLPPSLPPFPLPLPSLSPPPLPFPLPPPPSLPPPPSPFLLPSLFSFPPFPPSLPLPPHPSPPPPLPFPPSLPSLHPPPPLRRRRIHSDKSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYR0</accession>
    <name>A0A423TYR0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000951">
        <property type="protein sequence ID" value="ROT81587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYR0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="554" mass="60517" checksum="35AEDEB5461337E6" modified="2019-05-08" version="1">MQDNTVPSSRTVTSSHPHPAPADSLYKDLLGYSETLTHPPHPPTPTPCNPNYAPMHQPLPDALRSPFPTPFAAPHRSAGRRRVLSRVLLAELLFGSVPGVREAGAHKAACLPPLSTPMSALSRLPSLDPPNPSHFPSSTPQSPPSPRPQSPPLPFPRPQIPSSSLDPHPSTSPHPPPPPSHSVPRLSPHSPELRNHTTPTPPFAQSPVSLSLSRRPLIPHSERPPLTHRSPAPCSHQPQTPLDLDPNHADPHSLPTWPPLDPSATPSLLHPSDRLPLPTHTAPPLQQATPNLSRSTSSPLGRRLPWAPERIPASDKNRMKRGNRPHGLFFGGFLTGGKEARGPARSPAAHAFPADYPEENLSRREGGHTTWRATGEPPGKHGHQDHRQRGPFALLEPGSSAREPYSPYKQGTPPPDQLNCRRHRRARRGFLPARRETPSFPCSADQQRLRLRTNCRKQRAEPFNKAQSLRLAGGAGLAQQKCHREGTGTMRYPFTSGSRNSAAPSPTEKRDSKINLGSRLTCCFGNGAAAQRRALMNPSREAYFQPLEILSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4N7</accession>
    <name>A0A423U4N7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000652">
        <property type="protein sequence ID" value="ROT83673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4N7"/>
    <dbReference type="STRING" id="6689.A0A423U4N7"/>
    <dbReference type="OrthoDB" id="10069510at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19708">
        <property type="entry name" value="bHLH_TS_dHLH3B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000015">
        <property type="entry name" value="T-cell acute lymphocytic leukemia 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040238">
        <property type="entry name" value="TAL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13864:SF15">
        <property type="entry name" value="T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13864">
        <property type="entry name" value="T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="136"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="29945" checksum="3B06A4D135C67DE2" modified="2019-05-08" version="1">MVELKKAQAAGEFAFFRGTRLAQNIKVEDENSPPALGGCVGGCLGGCVGGCSGGDSKSPLPHLASVPRCAKAWPGRAVKVTSQAREQRGCLRDVHKCLRDTSTCDGNEASDGGVVLEVGLGEANEERGVVGHHRNIRKVFTNTRERWRQQNVSGAFAELRRLVPTHPPDKKLSKNEILRLAIKYINLLNSVLEWQRRQDDAGNGQRGSPLSPREACIAASTTSLRYRHHLHRPSSPQVISPPPEEGPQSTAARFHPYVLAVRVRPGLTLLHPQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5E4</accession>
    <name>A0A423U5E4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000618">
        <property type="protein sequence ID" value="ROT83944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5E4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="39261" checksum="E8119DA6D607165B" modified="2019-05-08" version="1">MINHFRRASLTPGASVLQGRTAAGRGGCSPPALAPRVPQQGLLSLLLDPADLLLEGAHLLLFKVLPHPSELLLEGADVLLPAPNPQAARIRARVGLHLVPGGEPKEFALAVCQELGQEVLSGRDEVAAVGAPSRGQPAQDVLDLLLELLEVALASENLDIRVVSVHVNPDPMQILQLLDPAASEADDGAAPLLSQGHGEPVAAVRAEAVAPFLFRSLAGDPGSFRSHRKDYNKYKLLGFSGHFRRASLTPGASVLQGRTAAGRGGCSPPALAPRVPQQGLLSLLLDPADLLLEGAHLLLFKVLPHPSELLLEGADVLLPAPNPQAARIRARVGLHLVPGGEPKEFALAVCQELGQEVLSGRDEVAAVGAPSRGQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6H8</accession>
    <name>A0A423U6H8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Diacylglycerol kinase</fullName>
            <shortName evidence="10">DAG kinase</shortName>
            <ecNumber evidence="10">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_022520</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.107"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01000566">
        <property type="protein sequence ID" value="ROT84296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6H8"/>
    <dbReference type="STRING" id="6689.A0A423U6H8"/>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20851">
        <property type="entry name" value="C1_DGK_typeI_like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20845">
        <property type="entry name" value="C1_DGKbeta_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000013">
        <property type="entry name" value="Diacylglycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000016">
        <property type="entry name" value="Diacylglycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10330:FF:000003">
        <property type="entry name" value="Diacylglycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047471">
        <property type="entry name" value="C1_DGKbeta-like_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF48">
        <property type="entry name" value="DIACYLGLYCEROL KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="13">
        <location>
            <begin position="212"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="13">
        <location>
            <begin position="277"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="DAGKc" evidence="14">
        <location>
            <begin position="386"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="631"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="638"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT84296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="761" mass="86198" checksum="62D9461E0DB4C4E9" modified="2019-05-08" version="1">MHFLSLLFLLCSSPTISLSIFILFSFPIFEIRFYLYIISFFFQIILIYLLFYPLFSFLFSRLSLSISSSSTLSLPHIPFFPPCFSSLPPNSFPLPPLSPLSPSPFLLSTLSILPSIFLFFHPSIFLLFHYFILSSFSPSTLPILFHLTLLSLFPSFIFSPLPPSPSSVFLLLDPFHFSFYFFFHPFFLLFHPFHHSFHLSLLLSFNMKEDGNHVWRLKHFSKPAYCNLCLNMLMGLGKKGLSCVFCKYTVHERCVQRAPASCIATYVKSKRTSQSMLHHWVEGNCPGKCSRCKKTIKSYNGITGLHCRWCHLRLHNRCASQVKPDCTFGEHRVHVLPPTSICPIVLDRQRSISKEKKGIPRSDSTPAGLSEGTVSTPMSFQITPLPGTHPLAVFVNPKSGGRQGARILRKFQYLLNPRQVYNLAKDGPLAGLQLFKDVPNVRVIVCGGDGTIGWILEQMDKVQWSVAPCVGIIPLGTGNDLARCLRWGPGYEGESLHKVLKKIEKSTVVMMDRWHIEVSEQTGTHEDMDEVADKIPYNIVNNYFSIGVDAAICVKFHLERERNPEKFNSRMKNKLWYFEYATSETFAASCKNLHEDIDIMCDGVSLDLSNGPSLQGIALLNIPYTHGGSNMWGDNATKKRTKATKSKKKKDRERELSTSSFTSADLSNAIQDIGDKLIEVIGFENCLHMGQVRTGLRGSGRRLAQCSSVVIRTRKKFPMQIDGEPWCQPPCTIHISHHNQVPMLMGPSTCRRKGFFSFMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7P3</accession>
    <name>A0A423U7P3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Estrogen sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_022069</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000505">
        <property type="protein sequence ID" value="ROT84724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7P3"/>
    <dbReference type="STRING" id="6689.A0A423U7P3"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="60"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="265"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="358" mass="41095" checksum="9EC180F6A66968B2" modified="2019-05-08" version="1">MALKLPVTVKDLPEERVQQRKAQGLNPLQAIVYTEPGDVLLPEPYKRAAEKLYNFKYRSDDIVVTTYPKSGTLWTMELVWAMTHLDQFQLPQKKHTNERVQAELAKVRPGPIDEECLTLQLAEAATAPRIIWTHLPLKLLHPDLLNTCKVVYVARNPKDICVSFYHFLMELKGRFFSGTFENVLDAFIADNLLYGPYWDHIRQARQQKDNPNFHMMFYEDMKTDILQELRKLSTFLGLQLDDAMLLKIADYAHFDRMKSNSELRPKLLRRQPLRGQAGRRLGPDRDPGGRGQDGPLDSRERQRLGLYLQIPMNGMRPCLPSRRASRESWPRCVWWAAPVTSSGSLGLLVSASLPGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U845</accession>
    <name>A0A423U845_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dpr6, isoform D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000479">
        <property type="protein sequence ID" value="ROT84883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U845"/>
    <dbReference type="OrthoDB" id="5969816at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF36">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 9, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00406">
        <property type="entry name" value="IGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="257"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="46111" checksum="60A5596C7B1BC539" modified="2019-05-08" version="1">MRSEDSFAGRAVRDAASLSPPSSIEVDYIPQQVDTPPPAPEDPGATQGEGVKKHLLQLNDIDTSDPRWVLTELFQKPSEAKVSKKLHHYKHHNKQRRKHRQHTGSRYHGGQYYSGQPPRQQQQYPPLISSDDEVLERHSLKHTGAPAHHRHDSLHHRTTLHDSKDYHQHRRHRQYSRHDDPEDDGSFDEQLYDHESREDQDEVKFTVGNGDYYSGGNTINALTEEDFKNIPGGEPRQYWGPTGGSGHAGQDPKGVGPRFDRSLPRNVTVQAGKSAVLACRVLDVSKTSQVSWMRHGDLHILSVGKYRYSTDSRISIKHNSEQHEWLLRIQDVQEQDAGRYECQVSSKPVLSFIVNMEVVANHAAPDEAPTSKQGQDFIKLLTRQERLCVPASREGRGLLERSFCMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA84</accession>
    <name>A0A423UA84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000234">
        <property type="protein sequence ID" value="ROT85603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA84"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="482" mass="54928" checksum="A36AF5F68E33C3EA" modified="2019-05-08" version="1">MSAPSLSFLAPISLYFWPALSSFYLQGNSLFLRPPKQLPFSQNLPSNSFFSDLPSNSFFFFLRRSASNPFFLRPPQALPFFSDPPQATPFFLRNLPQELLSEPPQANFLFFSDLPSNPFFFLRPPQATFFSPFFPQTSPSNFPLFLFSQTSQAIPFFSDLPKQFLSSSRTSPKQFLFLRPPQAIPFFSTSPKQFLFSQTSPSNSFFSDLPSFFFSDLPKQLLFLRPPQAIPFFSDLPKQLPFSQTSPSNSFLRPPKQFLFLRPPQATPFFQTSQATPFFSDLPSNSFFSDLPKQLLFSQTSPSNSFFFSQTSPSNSFLLRPPQAILFFSDLPKQSFFSQTSPSNSFFLRPPQATPFFSDLPKQFLFFSLFFSDLPKQLPFFSDLPSNSFFSQTSPSNSFFSQTSPSNSFLSASQAIPFFSDLPKQFPFFSSLQADLKAISFFLRQAPFFSDPPKQLLFSSDLPFLFFSDLPSNSFFSQDPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAB9</accession>
    <name>A0A423UAB9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000222">
        <property type="protein sequence ID" value="ROT85659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAB9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="140" mass="14844" checksum="3D76E3A6E9F1180B" modified="2019-05-08" version="1">MIIFRNGFKKVFSGCCPFIQYEREPPDVTRIQTTRFSCSGSPETHHRVSYDGSVHISMRTYVSEGGGMGAGGNCGRSSHGPLRLCNGANLRRATNGANARNYGGTGTLGGSGGSPMSGSSYTTTSAKKNAKFPSVAYQYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LU68</accession>
    <name>A0A3R7LU68_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-2-hydroxyglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="8">1.1.99.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019063</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-malate + A = oxaloacetate + AH2</text>
            <dbReference type="Rhea" id="RHEA:67460"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15588"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:67461"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.39" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01003500">
        <property type="protein sequence ID" value="ROT63062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LU68"/>
    <dbReference type="STRING" id="6689.A0A3R7LU68"/>
    <dbReference type="OrthoDB" id="5332616at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051990">
        <property type="term" value="F:(R)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2190:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000002">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000001">
        <property type="entry name" value="D-2-hydroxyglutarate dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051264">
        <property type="entry name" value="FAD-oxidored/transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43716:SF1">
        <property type="entry name" value="D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="12">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT63062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="46538" checksum="2633A1515FA0EDF8" modified="2019-04-10" version="1">MVRGASSVLLKPKTTEEVSAILSYCNQHKLAVCPQGGNTGLVGGSVPVFDEVIISMALMNQVESVDSWSGVVVCQSGCVLEALDQHVAEHGLMVPLDLGAKGSCHIGGNVSTNAGGLRLLRYGSLHGSVLGVEAVLASGEVIDCLSTMKKDNTGYDLKHLFIGSEGTLGIVTKLAINCPPRPTAVNLAFLGLQSFDDVLQTFRDAKSKLGEILSSCEFIDRSSLECVEENLKLKSPIEPHPYYMLIETSGSNGDHDEEKLNTFLEYVMTSGQVTDGTVATEPSRIQHIWSLRERIAESLIADGYTYKYDISIPLPHFYKMVEDMREHLGSSIIRCCGYGHIGDGNLHLNITSKEYEKEILSRIEPTIFEWTARVKGSISAEHGLGFKKRNYIHFSKSDGAIGLMKQMKKIMDPNGILNPYKVLPDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZA3</accession>
    <name>A0A3R7LZA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003504">
        <property type="protein sequence ID" value="ROT63017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZA3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT63017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="45955" checksum="D9FD413E8195405B" modified="2019-04-10" version="1">MTRPALLSSSPTAGYSRGNLVSLSPLPSFSFSLPPPFSLSISLCLPLPPFPSSYLLSSLHPLSSLLPSLSPFHIPPSPSPPSPFFFSLPPHFPSLSVFPFLSSPPTTPPSLFVFSFPLFPLPSLFYLSRSSFLSFPFPSLSPSLSVSFPLFPPPFPLSISLCLLFPSLSPFLPSLHLSLSPSFFPPPFPLHFSLCFLFPLLPLSFPLSISPVSFPLFPLPPSFHSLCLLFLSFPLPSPFHLSLSPFLSFPLLPSLHLSLSPFLSFPLPFLHLSLSPLSLSFPFLPSLHLSLSPFLSFPLPSLSPSLSVSFPLFSPSLPSLHLSLSPSSLPPPFPSLHSLSVLLSSSFPLPSLSPSLSVSFPLFPPPFPLSISPVSFSSLFPLPSLSPSSLCLLSSLSPPFSLHLSLSPPPSTAIKKAFKLRLTHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2G5</accession>
    <name>A0A3R7M2G5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002498">
        <property type="protein sequence ID" value="ROT69931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2G5"/>
    <dbReference type="OrthoDB" id="6155811at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018560372" description="CUB domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29221" checksum="8D02E8DE57AFA20F" modified="2019-04-10" version="1">MAVFGAPLLLVILALWGGQVSARQNMSRDECIADGGACVSPGNCMTPNRAAETCNGGSVCCNPTGLEAFKQTLELDGFEVDLRGWDPCSDRKCRKWYRGYWTPNPADCINKRRLVMHCVTNTTDLWCCAPPCRRKQICKELWGYCVPRKSHCPSGNTSHWMCGGKMCFCCLPPFPAPPCPWPAPSISICDHAIYNLAGEGDAVHVHSPDYNHPYENNLDCSLQVIAPSSCQIEVYLCEVSLEKCFFDTLTINNICTVEVSPNKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2L6</accession>
    <name>A0A3R7M2L6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">39S ribosomal protein L50, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016433</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003068">
        <property type="protein sequence ID" value="ROT65570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2L6"/>
    <dbReference type="STRING" id="6689.A0A3R7M2L6"/>
    <dbReference type="OrthoDB" id="9939609at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31542">
        <property type="entry name" value="39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31542:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="21526" checksum="890D9BEA41644D6F" modified="2019-04-10" version="1">MAASITKLRLLQSSQNLKNILNYRPLPIFQDVRHCSRSPVVAEEDGHELKDRRLDFDAASLAARGYLRSQKSYNPPKDVETQVLQLCEKTLNSTEPKTTFGDAATKYKLLSECSKKLKHKVPNSIMHKINNIEELMMFYKTPIDVTVPLDMMKNMDLPKNLHVIYNYTRFHPGMFSFCCCIFFMMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5G3</accession>
    <name>A0A3R7M5G3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin fusion degradation protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002780">
        <property type="protein sequence ID" value="ROT67673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5G3"/>
    <dbReference type="STRING" id="6689.A0A3R7M5G3"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000002">
        <property type="entry name" value="ubiquitin fusion degradation protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="2">
        <location>
            <begin position="23"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="210" mass="23923" checksum="1E878A376EEBC9B8" modified="2019-04-10" version="1">MMRNLLLDEGDLIHIESVSLPVATFSKFEPQNVEFLDITNPKAVLENALRNFACLTTDDVIAINYNDRIYEMRVLEVKPGSAVSIIECDMNVEFAAPVGYQEPERMDSAAALPEDTEEEMLPEPTGFYSFQGSGNRLDGKKKNLQLPQEELLKKLPRQRGIPDYDYEIGFIKFWRKLPKVNNTENKPEEPDEFESFAGEGTSLRQAKSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5L4</accession>
    <name>A0A3R7M5L4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative alkylglycerol monooxygenase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_008988</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5L4"/>
    <dbReference type="STRING" id="6689.A0A3R7M5L4"/>
    <dbReference type="OrthoDB" id="6354873at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050479">
        <property type="term" value="F:glyceryl-ether monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006643">
        <property type="term" value="P:membrane lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051689">
        <property type="entry name" value="Sterol_desaturase/TMEM195"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21624:SF1">
        <property type="entry name" value="ALKYLGLYCEROL MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21624">
        <property type="entry name" value="STEROL DESATURASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="8">
        <location>
            <begin position="127"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="44038" checksum="545F95884C6C3490" modified="2019-04-10" version="1">MNASVNESAAPGSLFAEALPGGAVCKGDVCRGSMWHPGIEDDPATIPRYTLQGLWWLVWLVGVEYVALWWQGARLPDLHDNIMSLVHGTLYEVSKLFVRGLEYGVYVWAWNKYSIFPPLGNSFLEILCVIVLVDFGFYWFHRASHEIMVLWAVHQVHHSGEEFTVSVGLRNSPLQRLFSWVFYLPLAVLGVPPAHMLAHVQFSALYQCWIHTETIRTVGPLEYVFNTPAHHRVHHGCNKYCLDKNYGGIFIVWDRLFGTFQPELPDQEIVYGIVYQPSAFNPLYHQVFYLAGALKKARSMSTWGDFVAALVKGPSWAPGSPWTGWEEDKLDEVIADAIVFLGQWVSVWGALAKCDRSPVHLARHSTQGLSIDLDSLCLSGDPRSHATSVTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7C0</accession>
    <name>A0A3R7M7C0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012752</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7C0"/>
    <dbReference type="STRING" id="6689.A0A3R7M7C0"/>
    <dbReference type="OrthoDB" id="6368475at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000033">
        <property type="entry name" value="Endoplasmic reticulum aminopeptidase 1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="11">
        <location>
            <begin position="2"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="10">
        <location>
            <begin position="146"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="271" mass="31021" checksum="F576EB2FF7536965" modified="2019-04-10" version="1">MDEELIKGERYTLQMEFLGYLNDQLRGFYRSTYRDDDGTTNCDPFPTHARRAFPCFDEPALKATFEVHLARETWMTSLSNMPLAETRPGRSGGLGVGPLREERPHVPYLVAFVVSDFSYIPSTSGKDTLFRMWAQPSAIRHAEYVSEVGSKILAFYESYFNVSYPLPKMDMVAVPDIAVRGMENWGLITMIDRSILYDPDVDSANHKDTLLEVVAHELAHQWFGTWSRPLVGRPAHSTRDSLLSWPYIGAHMYEWRVLPPYKGGVLEKKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9R1</accession>
    <name>A0A3R7M9R1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001606">
        <property type="protein sequence ID" value="ROT76833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9R1"/>
    <dbReference type="OrthoDB" id="6071166at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="530" mass="57764" checksum="8F0B907F47E5EEE3" modified="2019-04-10" version="1">MQLIFPRFSLLFFASFFSHYPFLLVFSFPFFALSSPINPFSSYFLLLCSLFSHYILFSSLLSPPPAGLIFLDSNPPHILLSFLYSFFSLPFFTLNPFFPLIQFSLSLSLRSGLEPPHIPPFPFLLFSSPFLSLLFLLPLILFLLSLSSPAGLEPAPDTPLSLVFNFDVMRRFKSMFVYLTTSHRDSEPAITATVKFGANSSFFDDVAVTSAWSESDLIPTGPQNLTFDLRKRPGASLQVTLEVRAMEVSIQEIYFDSTPHFTCRGGGGLQRRGKRAGAVVGWGGGWLRRPTHGKAPSPRVSAARRPTRWNMKSLMEGVGCRGFAAWMMGGGAPRPTYEEGSCLLYDDLQKTPLVSTLPHCRPRTPDSGATPVYATPTLRPSSTFPSAGASFSPIPRPVTLASLPRPPPIPPPPEKCDRQMQVRSRPQVFRPWGPSVTGPWLTSVYRQEATPQVASLTTPIYAPTLPAHQVTRTQILASGAFSTLSVGVVSGNADAQLDDEGERSSPPPPAATNHSDGSRGGAGCHASGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MA76</accession>
    <name>A0A3R7MA76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NIPSNAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NipSnap family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001672">
        <property type="protein sequence ID" value="ROT76331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MA76"/>
    <dbReference type="STRING" id="6689.A0A3R7MA76"/>
    <dbReference type="OrthoDB" id="10262843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051557">
        <property type="entry name" value="NipSnap_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017">
        <property type="entry name" value="NIPSNAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21017:SF17">
        <property type="entry name" value="PROTEIN NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="66"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="NIPSNAP" evidence="2">
        <location>
            <begin position="185"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="239" mass="27400" checksum="DA94F9712977F0FB" modified="2019-04-10" version="1">MATRAMLLRRAAFFSPSSSHLLHARCLSTTGHTAQKDSWLNKLLVRKIEPTKESHSRMLSDKEVIYELQTHNLKPGTGEEYLKNYATYVKAVADKPMHLELQGSWTVSVGDQDQCVHLWKYAGGYSAIDGANKILTSDSDLTSLIKDRNQFLRQRSNQFLLPFSFWPPVTPRDGGNIYEIRSYFLKANNEAFGGFFSQVGRLYNVHHIWCYKSLSDRKENRESAWRKPGWDEACAYTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBJ6</accession>
    <name>A0A3R7MBJ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBJ6"/>
    <dbReference type="OrthoDB" id="10056059at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="279" mass="30419" checksum="484356DCB3FD2851" modified="2019-04-10" version="1">MMAGSALECEEVRRLQHDVVIEEGEEFSGCGSEQETNTDRASRPLARESPTLLTYPEFHAPGTSSPLYPEKYFTLPAHLATQRISLPQAHSGAMPRFSSAAPAHVVSSQLLFRCNTSHLSLSQRTRGASSLRCRSFIIRPAPAVTHTTQDRSGRPRLRLADVEPQPGAMSYTIRGRISLHRPTPPTPAPTLLPTPAPLCVPNIYELYKGYLDDGALDPKAEALCLTAKISGTRERGRPRETHKDGLTLAPIKKMTPGELLHLSQDRGTSGIMEANVPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBY8</accession>
    <name>A0A3R7MBY8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_002692</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001357">
        <property type="protein sequence ID" value="ROT78602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBY8"/>
    <dbReference type="STRING" id="6689.A0A3R7MBY8"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050129">
        <property type="entry name" value="Zn_alcohol_dh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43401:SF2">
        <property type="entry name" value="L-THREONINE 3-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="5">
        <location>
            <begin position="44"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="339" mass="37278" checksum="A80163F1B6F5B941" modified="2019-04-10" version="1">MPVVMNTGEEAQAEASGGNTDDMARLVKQVSIESPTHKLKECIFNFETPMPEIPPAGARVKVRNAGVCYRLRSASSSSSIKSVDSLHCGSPLHHSVRDTALFPGYEVAGTVEALGVEVTETDLQVGDRVIVYPYEGHPPGYAEYIAVPDVQYLIKVPENMNLSTAAMLPSGALWAMNTVFSAHNHVEKVLSEKGETGQCKILLVGTGGLALWAMRIARFYWPQKRDRIVIAVACLRDEGISIAQEYLRVNVVQWNEDLYEEQLVERTKDACGGPVDIVIDFSATSRSIRRALKCLAPIEPPPHTIFSADRANEALAKIGRGYSWKGNLEFPEGYEDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCE4</accession>
    <name>A0A3R7MCE4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001315">
        <property type="protein sequence ID" value="ROT78909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCE4"/>
    <dbReference type="STRING" id="6689.A0A3R7MCE4"/>
    <dbReference type="OrthoDB" id="6339846at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="56"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="155"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="496" mass="53945" checksum="5AF0256308FAFB5C" modified="2019-04-10" version="1">MFLESVPVYFCLHHPYLFRDGVTGQSALQVAARYGAGNVVQALLSRRAEVDSSDNWGKTPLHEAAWYGQDDVVKILLQNNASFALHDKSGKVPLHEAVWFGRTAVVQALLEHGADVNAVDDNGLTPLHYASELESARILETLLDGGGEPNARDKEGMTPLHYAAWFGHEEVLTVLLNHEADMTVQDLQGHTALHYAVEHGELGAVKVLLEAGADIDAQDNNGNTVVHLACRSPEPLLMVPLLLLRCPRLTARNVIYKTAADVALDDGLSHLATLIDESNPVRCGGRLVAVSGGALAVTPLQPLTCNSSWALATRSLAHEDCWHRGQLYRHWASWYDGCRESKCVHGHLLQEPYTGTSCCQVGEDVYPENATWSQGCHHYRCTSGNATAIAVLTVCCSRGKNVYADGETWPEGCYRLLCKSGDVLTAGRLTSCCRVAGELHGQGSRWTNGCLLLRCQDGRVLHDAMTDASSSWAALLKQWFHTTIRSGGKGCSLAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDY0</accession>
    <name>A0A3R7MDY0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Actin-like protein 6B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001162">
        <property type="protein sequence ID" value="ROT80040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDY0"/>
    <dbReference type="STRING" id="6689.A0A3R7MDY0"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000375">
        <property type="entry name" value="Actin-related protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000043">
        <property type="entry name" value="AGAP008687-PA-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34118" checksum="76CBA77EC99900A2" modified="2019-04-10" version="1">MPLWNARGKRERLCELLFEKYQVPAFFLVKSAVLAAFANGRSTGLVLDSGATHTSAVPVHDGYVLQHAIVKSPLGGDFLLNQANSYLVESGVDLIPPYMITDKQVVKEGDRPKWTKKNNLSEVTTSWHNYMKREVVRDFQQTMLHCSESPYEEEAINSIPTEPYEFPTGYNMEYGTERYRITESLFDPSYIKGVGSTMLGMSHVVSTSIGLCDIDLRPSLYSGVIVTGGNSLLNGFVERLNRDLSSRTPPNMRFKLISATGSTERRFGSWIGGSILASLGSFQQMWVSKQEYEESGKSQVDRKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEA3</accession>
    <name>A0A3R7MEA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001938">
        <property type="protein sequence ID" value="ROT74088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEA3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="42727" checksum="36AE99D48ABA155C" modified="2019-04-10" version="1">MADGVSPNYTYTIPRSPPSSPLPLPPDNAPPSSLPDNAPPLPPSPPDNAPTPLPLPPITPHPHPSHSLPLPPPLPTSPTSPPQNARLSIPNHVTRSAFTYSRHRHDLSCGFMNARPRRSRDLCVAPGNECEACWRETPNYSSTNSLIFLIFLPTLPHIPPNSASYSSYPHALPNPPLIISPLSLNSPSSPHPHVASSPSQTRISTKPAFLVSLTPHNFQIFPLYHFILISLILPYPPFIPFSLISLTPHNFQIFPLYHLLLTSLILPYPPSPLIPFSLISLTPHNFQIPSYHLLSPPSYCHTLPLPSSPSPSFPSSPSHLKTPSFSLTTPLISSYIPNTTILPQSSSSSHIVHVPSPPLLPHTLKLLHSPSRLPSSPSYSLSLILPRLPHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MED8</accession>
    <name>A0A3R7MED8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial import receptor subunit TOM20-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001770</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001233">
        <property type="protein sequence ID" value="ROT79506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MED8"/>
    <dbReference type="STRING" id="6689.A0A3R7MED8"/>
    <dbReference type="OrthoDB" id="2154253at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016031">
        <property type="term" value="P:tRNA import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.10:FF:000001">
        <property type="entry name" value="Mitochondrial import receptor subunit TOM20 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.10">
        <property type="entry name" value="Mitochondrial outer membrane translocase complex, subunit Tom20 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002056">
        <property type="entry name" value="MAS20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022422">
        <property type="entry name" value="MAS20_rcpt_metazoan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023392">
        <property type="entry name" value="Tom20_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12430">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12430:SF0">
        <property type="entry name" value="TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02064">
        <property type="entry name" value="MAS20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01989">
        <property type="entry name" value="EUOM20RECPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00351">
        <property type="entry name" value="OM20RECEPTOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47157">
        <property type="entry name" value="Mitochondrial import receptor subunit Tom20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT79506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="11791" checksum="2E3301DCD6CC399C" modified="2019-04-10" version="1">MRSRKTAKSSAAGGKSVNWPNLKDQEAVQKFFLAQVQAGEELLAQGEVEAGVEHLSRAVAVCGQPQQLLQVLQQTLPPQVFQMLLQKLPAVGESILQAAGGPKVSEEDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MF87</accession>
    <name>A0A3R7MF87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ficolin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001147">
        <property type="protein sequence ID" value="ROT80168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MF87"/>
    <dbReference type="STRING" id="6689.A0A3R7MF87"/>
    <dbReference type="OrthoDB" id="6350391at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.530.10">
        <property type="entry name" value="Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018642268" evidence="2">
        <location>
            <begin position="25"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="314" mass="35180" checksum="F18B96A129D4ABDA" modified="2019-04-10" version="1">MRVTRPHAGVLAVVLIVALPFVASNNTNTSASAGGEGSVTVSVRKEGEVTGLLLFFGEGQEVTINGEQPETKCIRISNQREIEVRVIQDGVPQGESKSPQGRRGAAGGKREVIAQMELKNCLEVQNLGHNKSGVYTISPYELCPEHQVDVFCDMDTDGGGWTVIQNRDLSQGDFFRPWVDYVNGFGDLSHDFWLGIKHIHALTSQSPYEVRLDMTDFDNISRFATYDGFSLSDEAHRYEISFGEYSGGTDPAPDVENCAILWESVWWFKSCYTAHIEDEEQEGPNSKWLEVMWGYWRGYNYPPKKSEIKIRPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFT2</accession>
    <name>A0A3R7MFT2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box only protein 28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004588">
        <property type="protein sequence ID" value="ROT60744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFT2"/>
    <dbReference type="OrthoDB" id="8180181at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039719">
        <property type="entry name" value="FBXO28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252:SF1">
        <property type="entry name" value="DAMPENED, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13252">
        <property type="entry name" value="F-BOX ONLY PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="55419" checksum="CA460AF8429F4FCF" modified="2019-04-10" version="1" fragment="single">TCKRFEQIGSNILNAAFQRLQHLMSQRFQAIKGQMPRRESARRKHPLVREHDIVETLHMRLMLLQMSFGKHIERKHCCFFAGDILDEVHRILWYIKNTPTLGRAYKVTDELFDLSSMAMEYFKEHIEPRLPEITCFGSDFLDITTRYSDGCSVRPSGGSARVSEPEDDIPEFDTLPPSNMVLRKRIRRIRQGMRRYNTQLVALKRELKSCKSKLTDQHKQMMEYATRMDEYDKKFEESSRKFSTVLQELNKCKTELQYWRSKSPAHPLLCYGCGQAVGEGANQQLQAGVLMQGGDETVVFVPLAKASSQEGGESATPSAVFGRGSGRSGLCAMNGSVRNLERVFDLELSPSETSAVEPASHSKVVPETLPLAGVPLALSSVSPTSVSSPPIAPSHTHSAPPGTLPHVHSQPYSAFHTCGASHQTEQHRWDSSQECAEDLSMSRPFKHDLYDDGECGTLKRRVSDEESDNCDTSDDTVGRRVKERKRIKLDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGW5</accession>
    <name>A0A3R7MGW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative progesterone-induced-blocking factor 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGW5"/>
    <dbReference type="STRING" id="6689.A0A3R7MGW5"/>
    <dbReference type="OrthoDB" id="299638at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026205">
        <property type="entry name" value="PIBF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18950:SF0">
        <property type="entry name" value="PROGESTERONE IMMUNOMODULATORY BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18950">
        <property type="entry name" value="PROGESTERONE-INDUCED BLOCKING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="338" mass="38859" checksum="DD83170F45DA3F0D" modified="2019-04-10" version="1">MSGDASAEVSVPTDLTVTSDGESEDGFAASRRHARELQALASDRAELQRTVEKQRLELQNKKAQIAAITAQNESAVASAIAQKDDIISAKQIQANRLEAELVRTREELSTIKERAARELAQLAQKCATFQETQKKLTFRHEELRSSLTNLQISESEYNRLRRVSAQQLTLQQFTALRVYELVWPLKIKVNELETVKSSLESSLAAKDLDLKARSDQCRKQQQELEDLRSKSEHYASQLLNLKEEQRSDDYKARNYHRVKSERDQLEGERETLTRKSTELELLVATLKKERSLLEERFGELKDINPWRQNMKRPSELQQPSLKKKPIVCWTECPQELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKG8</accession>
    <name>A0A3R7MKG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017991</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003329">
        <property type="protein sequence ID" value="ROT64087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKG8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="51472" checksum="27A9F796B16AD5BF" modified="2019-04-10" version="1">MLFPPAHLFPSSSSSISLIFPPPIFLLSILFILPPLNFISSNLFSSSLIISPPPPSSISFSSLYSLLHTIHPLIPISSSSIIISSSLFPSSSSSISSSSSHLFPLSSLFPPSISSYSSSSYHLFLLLLLIYFLLIIYFLSSPPLIYFPPSSPHLFPPPHLFPPHFLIISSSSLPIPSQSISLLLLPLISLSPPPHLFPLSLLLIHHYFLLLSSIYFSIIIIIYFSSFSHHHLFPPSSSIPPPPHYFHQSSSISSSSSSISSHHHHVIIYFLLILFPSSSSSSISPHLFLLSSSSISSSSSSSYSPSSLIYFLLSSSILLIIKSILPPHFNHHLFILSSSSSISSSSSISSLFSSYHLFFSSYIYFLLLSSILSSSSWEAVECGSEQDREQVKKCGRSHKSSDCEQKHTYFVMPHSHKCWIKWCAVTGRKPVITLMIHLGHTLDVTTSKQQCHDQENSFKIYNSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML85</accession>
    <name>A0A3R7ML85_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="24">Vitamin K-dependent protein C</fullName>
            <ecNumber evidence="23">3.4.21.69</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="27">Anticoagulant protein C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="25">Autoprothrombin IIA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="26">Blood coagulation factor XIV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="33" type="ORF">C7M84_017423</name>
    </gene>
    <organism evidence="33 34">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="33 34" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="33">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="33 34" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="33">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Degradation of blood coagulation factors Va and VIIIa.</text>
            <dbReference type="EC" id="3.4.21.69"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="28">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="33">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.69" evidence="23"/>
    <dbReference type="EMBL" id="QCYY01003221">
        <property type="protein sequence ID" value="ROT64620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML85"/>
    <dbReference type="OrthoDB" id="6286622at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007599">
        <property type="term" value="P:hemostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000011">
        <property type="entry name" value="Coagulation factor X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000009">
        <property type="entry name" value="Low-density lipoprotein receptor isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050442">
        <property type="entry name" value="Peptidase_S1_coag_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24278">
        <property type="entry name" value="COAGULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24278:SF19">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 28" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="20" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0356">Hemostasis</keyword>
    <keyword evidence="12 29" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 29" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-0675">Receptor</keyword>
    <keyword evidence="34" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="14 29" id="KW-0720">Serine protease</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EGF-like" evidence="31">
        <location>
            <begin position="307"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="32">
        <location>
            <begin position="388"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="30">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="30">
        <location>
            <begin position="591"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="30">
        <location>
            <begin position="85"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="30">
        <location>
            <begin position="607"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="30">
        <location>
            <begin position="634"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="30">
        <location>
            <begin position="680"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="30">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="30">
        <location>
            <begin position="703"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="30">
        <location>
            <begin position="725"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="30">
        <location>
            <begin position="736"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="30">
        <location>
            <begin position="750"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00036045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00037553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00038995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00040219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00041306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00042403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00042906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="31">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="32">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="33">
        <source>
            <dbReference type="EMBL" id="ROT64620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="34">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="930" mass="99409" checksum="C068044AF69106B6" modified="2019-04-10" version="1">MKTAVSSTKERAKALSPATTVSFGLPNFSFGGGGNGRQDGNNLGSFIGGAINGFINAQNNRPNNGNNNGGGGVTIINPFDLFRPNQGNNGNNQATTSSPATTTNNNQGTTTQNNGNVLGNFNIAGLPIQVTGQNGGIGISFGQNNCGRDNGGCEQECRIIRRRPRCSCREGYLRNPDRRTCSDLDECRQNNGGCSDICTNTPGSFTCSCRQGVLQDDQKTCSRAVEHCALNNGGCSQICSMNGGQFVSCFCQPGFTLGPDRKTCLQLDQCVSNNGGCQEICTNTQNGPTCSCGPGKVLNNDRRSCRDLDECQFNNGGCQQICTNTVGSFECSCRDGFQLVGNQCQFVIRPPVTAATTTTNDHSSPVVTPPPAVNGCGVNPKKSLFRRIVGGKPADPKDWPWMVALLQRVGNTQYCGGTLITDRHVLTAAHCLRPFSASEIKVRLGEYDFSSTADNSPTDFDVADIRMHESDKVIFKPFLLLFLSFTTSPSLLTTPSPFPSYSSHHHSTPLLAIPSPLPTPLPLPIFSILPISFFFLSPALKTFSLSPYLPPIPHPLSLPLPSSLTPLPTPFSSLPIILLLPLLPQSTPTLPLNSHSALPDPMPTSPPSLTLSPAAPLFPTHQPPSLSLSLPQLPNLPPPLPPPPTSPSNPTPSPTLLLPPPSHNPHSPSPLSLLPPAPSLPHSFPNLHSHLTSPPPPRPLSPPRSHLPSPSPSHFFPSQLHSFPTPTPTSPPPLTRPSRTAHSPPSTSRPLPPSPLPTPFPPPSCPPSPHLLPLPSRPRIPTRFAHRQRREPSRATARSEFISPVCLPPAGRSFEGNLGYVTGWGTIYFGGPVSQTLQEVIVPVWTQSECTAAYPGRIQSGMMCAGNRQGGQDSCQGDSGGPFLVQILPSRRWYIAGVVSWGIECARADKPGVYTEVSKYVDWIMNNAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQT8</accession>
    <name>A0A3R7MQT8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000677">
        <property type="protein sequence ID" value="ROT83492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQT8"/>
    <dbReference type="OrthoDB" id="10006218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="552"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="597"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="621"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="714"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="821"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="854"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="209"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="875" mass="99825" checksum="F59DD22FB97DD3BD" modified="2019-04-10" version="1">MQVCEVFPPPSPPRGEVPTPMISFATCLSQVKFQGLMQMVGHLGSCFLREERRGINGHVSVCWQLPRCSELSALHLSVRFKMMTSYRFLFIATLILIVVAVYLRVQSDKSGVLSASDLEESLNKFQQNLQESLKGPERTDLNKMSEVPFQKGERETTEEVVILDKKCSLRTSLDSDKLYRYMEKVTAKCEMPVMVGGTARTKEPYIWNEKWMCLDARFNILPGKCLVYSFGISTDWSFDDDMDKRFNCKVNCFDHTISKKDHNRSSNINFYATGIAAVKGAKVDRYINILRRLGHENATIDYLKIDVEGAELQFFEDVFTNTPEVLNNIKQIGMEIHPGKSENRKKLYLRYIQLLECLGFKLIFSHILNVPQTQFREKGEQSLSLFYLPFSPLILPPEFSHTSYIPKLSPSTYSYFLSSLHLLLLIYFPPLFYSHPFFSFSLLILLITHSSILSYISLCYLLSLSHSNLLLAHFLLPLLTYSPPLSILPSPFLSTSISSHPSGPLTSPFFLPTLYSLSSYLFFSFSSPLLFFPLPFSPFFSHFFFSFSLNKIHFISLFLLLLSFYSSSFFLISFPFYSFLCLLLFLSRISYTYPLDFSFFSMLRFHLSLLIFSYFPCSIFWSFFSLFPSLFLIIFVALLSLSSLSSKYPLACLYPHFLSALLPLLPLLSHLTPFLHSLLLPSSHLPSSSQISFPFSSSLQFSAPQSSISPLSSFLFSFLVLLVSFFFTLILFFLSPLDSPSSSLLFSFSSYSPSTTSNSILFFLFPPLHLLLYRLPSPFLSSLPLLLFLFSSQVSLLSSSTISLYLLLFSFSSLHIPSPHLALFLPLSLLPLQYILLPYSLFSLFLPFHYSSSSPIFILLFSSSPISFLLYFISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MU91</accession>
    <name>A0A3R7MU91_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transient receptor potential cation channel subfamily A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_011904</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002509">
        <property type="protein sequence ID" value="ROT69858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MU91"/>
    <dbReference type="STRING" id="6689.A0A3R7MU91"/>
    <dbReference type="OrthoDB" id="6364028at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902495">
        <property type="term" value="C:transmembrane transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF1">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="628"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="729"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="8">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="797"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="853"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="797"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="811"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="858"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT69858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="872" mass="98513" checksum="727D49287D8BD822" modified="2019-04-10" version="1">MTPLHIAAKKKLPECCAAILRLPYEEIFLTSASSDLDGRESVRGGADGERSRLSLDVSTESIRDTERTAKTKVDVNIKDNHDMAPLHYALEKQSVECCLLVIKARANVSLISSGMNRPLHLAAAAGLDRACSRILAKGASAKEENDMKETPLHLAAKAGSLACCRLIYRSGANCNALDKNGMTPLHHAARIGAEDCCRFFLAKRVNILRDCIGRTPLHIAAAEGHLSCCELMLTAETSWQLDVMDCHGYTPLFRAFENKWDDVFVFLLLKFQHRAPRNQHRPRKDSLRLLKSSGSGDLSHRISAAEQSTSQNDMSLVLSRCIQERRSKAVEGIVRSEFWGDALAPTAAHQSNFRLLIIHYPELAKVVLDNCVLSRPSCKVFLFYFLDDTFTVPTIEDLGLPDRPAWCPFTPEGWLEDSATLKDDSEDTWRNEHPLSLMAKHKRLDLLKHPLCQRFVSYKWERYIWRVFYALFLLPSLFVVALSVYGTMAYDWDYVLQEFNISRGQLCSSEGAGRGECRSPGGAAFRRSFAADECLAEGKAAGYGPNEVLAILRESQINLNLLEKFVWLMLLLKVGLEAQKLHHLRRTNLEKCLQLACYLTSAVFLYNWTECSQVTGVKEDLQWSCGSLAVLVAWFDLILMLGTIPTFGVFVFMINDFLRFMLKLFVIVLLQVIAFSFAFHMLLRGRASFRNLPRATMKIVTMMLGDLGYDDLFNNTESPLPYPMVSNLVLVYFLFLMVIGMINILTNFPQEVLDKAKKQTELMKLSRPLKAVLEMDSKFPLLRRRYTVGWVVDGPQKEDEVDGKQRKDGEEGSDSDEDALGEPHRCCSCRKEPSENLLLKILNEVSALSENLEDRRYFSPHRRSNSTRGSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N2H2</accession>
    <name>A0A3R7N2H2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Xylose isomerase</fullName>
            <ecNumber evidence="4">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006004</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N2H2"/>
    <dbReference type="STRING" id="6689.A0A3R7N2H2"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48306">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48306:SF1">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0859">Xylose metabolism</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="236" mass="27260" checksum="FE1F644FBF40E661" modified="2019-04-10" version="1">MSHMAQLYRMAAQYRDKIGFRGQLLIQPKPADPRRHQYESDAMSTMHMLRHFGLDKHYKLYIKPAFARLTSRPYEHDVYMAAAYNMLGCVDASDSWPEFNGTSDICAQDMRDATLVMKCVLEQGGLQQGGFTLGGRVRRESTEPRDLFHGHIMAMDTFARALRNAARMISDGSFSKSVQQRYASYKSGLGERVEKGSITFDECEEFVRKTGEPQPQSSRYEHYQNMFNYYVYPPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NBZ2</accession>
    <name>A0A3R7NBZ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative PPE family protein PPE40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000745">
        <property type="protein sequence ID" value="ROT83053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NBZ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="47599" checksum="9978BE0FDF1AA1B1" modified="2019-04-10" version="1">MLNLFNKCLSDKHTQACKKTCSTPQHTTPHRSTPQHTTPRHSTPQHTTPRRSTPHHTTPRRSTHTHTTPRRSTPHHTPHTRRSTPHTPHHSTPPTTQSLHSTTHHTPSLQSTTHPHPSLQSTNTPHPIAPLHNTPHPILHSTTHHTPSLHSTTHHTPSLHSKHTTPHRSTPQHTPHRSTPQHTTPIAPLPSLHSTTHHTPSLHSTTPHPIAPHNTPHPSLHSTTHHTPSLHSTTHHTPSLHSTTPTPHRSTPQHTTPPSLHSTTHHTPSLHSTTHHTPSLHSTTHHTPSLNTIQHSTPQHHTTLHSTTLHSTTPYNTPLTPYNTPLHNTHTTLHSTHNTPLTTPTHTNTTLYNTTLYNTTLYNTTHNTTTQPQLHNTTLYNTTHNTTLYTQHNTILHNTIQHNTTLHTIHIIHHSTPYIPHTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NWW4</accession>
    <name>A0A3R7NWW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Core Histone H2A/H2B/H3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT69000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NWW4"/>
    <dbReference type="STRING" id="6689.A0A3R7NWW4"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000047">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="3">
        <location>
            <begin position="44"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="17620" checksum="13F074291C6A1183" modified="2019-04-10" version="1">MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDPLPVLCCHGSAGSLRGLPGRPLRGHQPVRHPRQACNHYAQGYPTCSPYPRRARLRFWLLACLHTSKSSSSALFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P4W7</accession>
    <name>A0A3R7P4W7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001765">
        <property type="protein sequence ID" value="ROT75496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P4W7"/>
    <dbReference type="OrthoDB" id="6379273at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33198">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="646" mass="70817" checksum="DB263421C1E3E34B" modified="2019-04-10" version="1">MATPQEDHFQARNDDLGDGSDDSGEPNVLESGEADVPSLPPPLTPHPSSPSQHSPGNQELQYLLHYLQLLSMIAPKPLQVQQTSPDQQAPAAHQLSPVPPVATTSGSPHAPITVPVMATVDVTYQMFHQWRRKFEDYSVLMGLHSLPPATQHIYLRTCVLLEVQRLLHYTLAIPPDSSMPVVQVLDALQQYFRNLQNKALRRQELLSCKQTPGEPFSAFYASMKDLADELCTGDRTTCAATQLKMILLMGVREEELVQRLVSPDSQASLDDFITCCRTFESSSAAASAIVAAPSQLNILSSYKRNQRRQKMTATTKHTPQCCQSPPLTKNSPASCRSCTRQHAVGHCPAKNSTCPNCGYKGHWHRTPRCPAKDSECTTCHKQGHFAKCCKSTRKTSTNQTRRARRVSTGRTPKPVNVTLSYGSKSSQLLMLPDTGADITVIGLKHLDSLGIPRCSLSPPPATDVLTADGSSMTPALDCFETTLQLGQASCKAIVHVYECIQTPLHTYGHCVDLAIVSTDFPKPILSVTHVNRCAQQMPASAVSFPTAARTYFLQHFSDVLVSKTDLQTTPLKKMSGPSIEDSPSARSRRNSIPWCKGSFRPSVTSPPSGAIRWSWYPKPGNGVRITVDLTHLNFQVSRPTHPSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD46</accession>
    <name>A0A3R7PD46_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-amylase</fullName>
            <ecNumber evidence="3">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_020235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003912">
        <property type="protein sequence ID" value="ROT61945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD46"/>
    <dbReference type="STRING" id="6689.A0A3R7PD46"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-amylase C-terminal" evidence="4">
        <location>
            <begin position="77"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="27709" checksum="93844AB9EEC2BD48" modified="2019-04-10" version="1">MGVCFSLAHDYGFMRIMSSYYFDNSDQGPPGSSYGGTDDVPINGDGTCGGGWVCEHRWNAITQMVKFRNAVAGTQIANWFQEGDNVAFSRGDKGFFAMSKYGSFDRTLQTGMPAGTYCELISGCANQVTVNGDGTAQISIHNSDEPIFAICVGCDGNGPTVDPNQPTTTPGPTQPPITSGAHRTVVFVHKQTNPGQDLFIRGGIDSAHRPVRRVASRRHEAGLVRRAGRPGQLHGAGGLRFAACLDHQPGRGRWTPGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDU0</accession>
    <name>A0A3R7PDU0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000745">
        <property type="protein sequence ID" value="ROT83058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDU0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="106" mass="11997" checksum="7C8F7F201D696B1A" modified="2019-04-10" version="1">MNEVTLEVAAGLNSTLSQVTSALRWVLACLTSVLLDEEGQVSTRSLQQVRAFAIILVVNFVLITVFWYVYAQRISHTLSYNSLRIVEDILKRNTNFKINKDNPARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE26</accession>
    <name>A0A3R7PE26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002739">
        <property type="protein sequence ID" value="ROT67903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE26"/>
    <dbReference type="OrthoDB" id="6396562at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="290" mass="31927" checksum="C15EE215A4D12FE7" modified="2019-04-10" version="1">MRGGRLLPQSFAGGREPAEDTTPQTLPGVHAGRWKGGRLRDTAPREANAVLREKSLISRGPRRSRSSLPRRESDRLKMAAALLPGLLLLALSLGFPLASAENRALPRNLPSIMFLKPGQWSTSVIFKVLFEDAGVQNASFSLNMQWYAVELSRNENKTVVLRIPPHSVKEFPCCTGKELLNYHASYEGDIEWSEACPEDAPEDLLALCPTTESTSDSGNSTTKTEDLDAETKKILWIALPTGIGLLLVLVVALVCFLYTKSREYQPPTDVSYPARSRFDNGVASEEEDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFE9</accession>
    <name>A0A3R7PFE9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003217">
        <property type="protein sequence ID" value="ROT64647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFE9"/>
    <dbReference type="STRING" id="6689.A0A3R7PFE9"/>
    <dbReference type="OrthoDB" id="643377at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF140">
        <property type="entry name" value="IP22191P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="200"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="351"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="469"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="593"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="677"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="504"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="730"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="740" mass="82544" checksum="14E3A7806BA12348" modified="2019-04-10" version="1">MTGNSLVILSHEKFKMMQLTNLQRIYVSRCKLLQLDDAAFRGLTNLVELDLSNNELTLVPAAALEHVPGLMRLQLSNNPITKIKDGSFKGLKYLNTLEMTSCAIQTLEPRAFQGLDQLEWLKLDANQLQSIPHKMMLPKSLHGIDLHNNLWKCDCHLLQLRTWLVKYNVPSSIEPKCSSPPRLQREIIKNVHADDFACPPEVRPTSFYLDTMEGKNVSFECHVTAEPAARIFWRFNGQSLENSSFAYDESSSFYIFEESGTNDDRVSHLRIEWVTEAHAGVFQCLAENQAGLVISNFTLRISQPIVEPIEENFVMDHMVYIGVALVSLVALVIILLCVLIIRCCRRRSTTHEKVTGSPGVSGNGRPKEGQAPTTNNMPKYIQMGTPAPKVNGISSDPPPISVIDSSPYRSEPTGAPAHPNPDLISDAADDRGKPTKKRVSILGVEEVDACGQRTTRKLDDIIEEFEDGYDPTYDQLHPPSDHENHHSNRSNPYSTLPRRRDPEPTNPYPLTEIPPPEEVNQGSRFYDVDGFPVDYGLPRNGNGNGNGQGLSSSYNPLPTETIPVYATARRTRPGSAPRPELMHDQKYPEEYRLHSHDPHYHPPDGRYPQAYGLVPEKFSDPTNGSCEFCPPPPVHPDFTTEPGGRIGGDGCSFDNLLSSCGGGSQCCYAEQSGRLYDNSLPENYRPLDPEPPPPEGWGDQDQETVNLSTWCEHPESPGTRVLYSPDETYPDQQPPQGTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJF0</accession>
    <name>A0A3R7PJF0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Polynucleotide 5'-hydroxyl-kinase NOL9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_013311</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002659">
        <property type="protein sequence ID" value="ROT68510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJF0"/>
    <dbReference type="STRING" id="6689.A0A3R7PJF0"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057570">
        <property type="entry name" value="NOL9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057573">
        <property type="entry name" value="NOL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24419">
        <property type="entry name" value="Cupin_NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25467">
        <property type="entry name" value="NOL9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NOL9 N-terminal" evidence="12">
        <location>
            <begin position="129"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 P-loop" evidence="11">
        <location>
            <begin position="290"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="NOL9 C-terminal" evidence="13">
        <location>
            <begin position="519"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF24419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF25467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT68510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="659" mass="73995" checksum="141939C6629423CE" modified="2019-04-10" version="1">MVSQKKERQGKDLKQKKSLKNCNGSSPIKAMKGNARNGISTDDKEAKVDVQGQDKDIERIAGNANETSKKKKKKSLWTTPSPKKKQKTAATDCEVEEPDQSKGEAIGKDNSCDSDSEDAERKIITDVDMEEHYNVYFQGIARVHLIVGSVKISGYELEEGEEHTVYSLLSHSLLALEAKKGIDLSIKKDIPGVPKDWIKELMSDEIKEVIIVKMTHHFPPMAKLLYVAGWRDLVDRAKDPTYGLKSLHLISRGSSRRYPLYQEAPEWDAALENIKSSYRRGKMPCIVVAGGQKVGKSTFFRYLVNSLLSMQRSKGVLCLDFDPGQTELSLPTCLTFLHVKSPLLGPPYTHLTVGSNDSCKQILIGTSTPQFVLQKYLNAVQSLSTFSRNYESLPMVINTMGWSNGTGIDLILDVIRITQPTHVIQICSEKRQFNYPFFLNSETVEGHRGGIATKPGSSYLEHQMIPLRSVSVLKLSMCNSSSLREISVLSYFSKIISQEGKNEKSSMKGIVKIKWCDVVLHVFSTEVPREKILQALNASLVTLCKVDPNDIETVGPYYPKQLVQDADFKDIIGWGIVRGIDPLAQELYVLTDLSEETVASSVNAIIMPDLYLPTHSYTLFAENSKEAPYMEQPRKEDRVELVKDRVKKRSKYSVRNMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLN2</accession>
    <name>A0A3R7PLN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inscuteable-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002417">
        <property type="protein sequence ID" value="ROT70504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PLN2"/>
    <dbReference type="STRING" id="6689.A0A3R7PLN2"/>
    <dbReference type="OrthoDB" id="5796379at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045179">
        <property type="term" value="C:apical cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008093">
        <property type="term" value="F:cytoskeletal anchor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045176">
        <property type="term" value="P:apical protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008356">
        <property type="term" value="P:asymmetric cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009786">
        <property type="term" value="P:regulation of asymmetric cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21966">
        <property type="entry name" value="INSC_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.200.10">
        <property type="entry name" value="Inscuteable LGN-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045789">
        <property type="entry name" value="Insc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038205">
        <property type="entry name" value="INSC_LBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039921">
        <property type="entry name" value="Inscuteable"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21386">
        <property type="entry name" value="INSCUTEABLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21386:SF0">
        <property type="entry name" value="PROTEIN INSCUTEABLE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19427">
        <property type="entry name" value="Insc_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein inscuteable homologue C-terminal" evidence="1">
        <location>
            <begin position="103"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="591" mass="63788" checksum="AE787D5EFBB1314C" modified="2019-04-10" version="1">MEDQEVRVSEVFPGRLSRVGVRGSNSPVAGPALKPIIKSMAGASRGRLAGPNGSVSQWLSELRTLYEAECMNTLQSKSVPGESGRRCPSFPSTRDAVRAIQRRAHAVSTEFARLCQRLEWLELTRCPCCQVPGVHINTFLKSTLHHARGRPPARTEPIVIIFRSSLGRQSKVIEQICQRLTDVCGDDHTREADEQDTTRQVVQVVTALGHAFTKLVDLMLSREIKVVVAALEEPRSEKEVSSAVSHLTALGVDGGHICRLIARLGGVRALLSLCLEPRLRQVRVASLRALATVCCVVEGIVELEKAGGVEVVAEVLCDEASPEEERSEAAGVLAQVTSPWVEDNHRLAGLHDNMDAIVAALTGLAERTRSAEIFLLASAALANLTFLDGGCVGAMRRAGTARVLLRAARGNPSISIFTKDQIATVLANLAGSRGGGEEVVPRGRVVLLALLNTRPAPSHRLPEVATAERVQQKSAIALSRLCGDADVARKVAQQGGAERLVQLCKDEGERNQSDAVLVACLAALRKMASSLGSDELRDMDAAELVEPRLLDSFLTYSSRQESYTFPDVTLAFPTLIAPLPTHPVICWYKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMD9</accession>
    <name>A0A3R7PMD9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002330">
        <property type="protein sequence ID" value="ROT71211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMD9"/>
    <dbReference type="OrthoDB" id="6363632at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21881" checksum="3C1E870BB5CCBE29" modified="2019-04-10" version="1">MTKHKVSPTIDSQTDVEKRVSPTSLSARKGKSGISRDSSSVRNDAATVSITECQALKLPKRKGRKTVRKKIAVRDLFSTCVAPKGGSTSWYELREKLKQHRFEGNTQAAILSVRHPLSRLTSAYRRRDACDTPWEIESQEATRPWQAFTYDDQGIQFEMAEIKGSTILHEDPNPGGNAVAQLWNSLLLSSPTVVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNL9</accession>
    <name>A0A3R7PNL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Down syndrome cell adhesion molecule isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_003557</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001483">
        <property type="protein sequence ID" value="ROT77750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNL9"/>
    <dbReference type="STRING" id="6689.A0A3R7PNL9"/>
    <dbReference type="OrthoDB" id="6370519at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056754">
        <property type="entry name" value="DSCAM/DSCAML_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF56">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25059">
        <property type="entry name" value="FN3_DSCAM-DSCAML_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="12">
        <location>
            <begin position="66"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="12">
        <location>
            <begin position="266"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="12">
        <location>
            <begin position="357"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="446"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="12">
        <location>
            <begin position="583"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="12">
        <location>
            <begin position="680"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="542"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="790"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT77750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="868" mass="93645" checksum="329044034A119C12" modified="2019-04-10" version="1" fragment="single">YSVEVVEDSDPDRSVGKGSPAGGVRAEVRVTNVTPQDSAVIACTATNAYGSHTHNMELKVQDVPEAPRDLRVTREGSRSVTVTWAAPPSPNTPITHYVIHLKTQTVSWESNSVRQLRTEGSSTSAVLEDLLPAKVFQRGESPSSEPLSLRTDGEAPSAAPVTVRAVGVSSREVQLTWAAPDPDTWNGQLLGYYTPPPLFLSPVGSGRSFSFDTVGVTGGGEESWTVGNLEKFTRYVFVLQAFNAKGPGPLSTEVFATTLEDVPEAPPEDVTCCPDLDAGGGLLVAAPRPPRPRTHHHVHADLHAHGRPYRGRDRSATVGDLERYSNYSVTVAAATRAGVGVSSPPVVCATEEDVPQAPRTIKVVMNGPNSVIVAWAAPQRAHGTVTKYILYRRAPPARDPIRRILPPQTLWLEVTDLASNHLYEFWVTSATRVGEGPASPVVSATPSATVSSGIYSVGGEVRAGRGTDVVLPCQHVGRPTPTLSWRRDNAPVTHDSRYEPQLDGGLLIRDCQRSDSGNYTCHASNRHGSDHVVYHAHRHGFYPNHQTKNINPNHQDEQRPPYSSSTPPPFLPSSNSPSPPAVPPAAVLLHSMGSTSTSVTVSWRHVDDGGAPVRKLTLTWRPDPGEWREVTLARHLTQYTLGELTCGTEYHLYLTSHNKIGPGAASEVITVRTKGSRPSPPPQHRLISVNTTAVTLRLTSWADQQCPIAHFSVRFRPSNQGLQMVSGRLPGSQKEYALGDLAPATSYELSVTAQNPAGETTAAYNFITLGLTGVGCSELPLLLPLLTTHTPLSITGPPPPKKPREKKTNLDQGVRIPTEALTEALQKGAPDGGAVGGRWRRPGHFFQITRRDGQYNEPTTPRFPARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRK5</accession>
    <name>A0A3R7PRK5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000826</name>
        <name evidence="3" type="ORF">C7M84_000866</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001123">
        <property type="protein sequence ID" value="ROT80416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRK5"/>
    <dbReference type="STRING" id="6689.A0A3R7PRK5"/>
    <dbReference type="OrthoDB" id="6381127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="51215" checksum="DA34FFADD26BD294" modified="2019-04-10" version="1">MDLMGPFPLTERGNQYILVIVDFLTRFAVVRALPNKYAETVAEAVSEVFADLGIPQTVLTDQGREFRNEILKEMAKHMQFQHHKITAYHPASNGLCERTNQQVLNILRGMVDGKDQYWDLYLKDTQMALNSAYHKAIGDTPYYAMYNRDLKTSDLWWTRPTSFGGPPDEDFITARTQRSKEVYEYVRDNLLRAADEQCRIRQKKSKDTTVLPGMRVFIKAVKKKGDSKLSPRWEGPFRVVEQIRPYVYRIKHLQTEKMKEVHLENMKIALEASIPRSLAPEARRPYPQETHSDIRPEGTSEEEEAREEEYVMNFPTNDDGKGTSESNQDWAQESSEVDDLAQDVVAGDSNNADKANVSNNVNVLPSMNVDESDGLQTTDSYNIRHDTNTKDLSPKPEVATNDASASTESERSNNKTVHDELSEHGRRTSGRTRYPPGYYTRLHEGPQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRW5</accession>
    <name>A0A3R7PRW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006428</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001815">
        <property type="protein sequence ID" value="ROT75062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRW5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018701065" evidence="3">
        <location>
            <begin position="20"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="597"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="633" mass="72303" checksum="479CF9173DA909B9" modified="2019-04-10" version="1">MARTVRRSLAALLLSLATAIREFITSESSLTSDEWPRGDDEQIPPVIPRIGGDADDDDSRRMGCSNGFSSHPRKPTRSKKISASLPCSARGVSSRASRRNASARVPFDKKCNIQCNSSLPRTFWTLAGTPRRLPGTRNAFQKLRISSRIPAKASRGRSGGRVLHTAEDYAPSPTLFRNLNIYSSSSIFRVPFSPFLLSFLPFSLFLLSFLPFPFFLSFFLLSSIFLLSFPFYLLSSFPFPFFSSLLPFSDISLAYFLSFFFCLRLSHPLACLTKKPHLPFFVFPSPFFYFHPSLFHFPSFPLPFSTFLLSLFPFPFFFFPSSLFLISSFPFPFFFFPFLLFLFRVFSFFLLLPPPFPSFGVSYREASSIFRLSFSLFHLPFSVFLSRIFFSPSASAFPFFAMSYRETSSSIFRLSFSLFHLPFFPILSFLFRVFSFFLLLPLPFPSFAMSYREASSIFRLSFSLFSSSFLPYSVISFAYFLSISFCLCLSLLFMSYREASSIFRLSFSLFLLPFFPILSFLFRVFLSSPSASAFPSLPCSYREASSIFRLSFSLFFFLSSLSVISLAYFLSPSASPFPSFAMSYREASSIFRLPSPFFFFLLPYSVISLAYFLFSFCLLLSLLLPCLTEKPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTP2</accession>
    <name>A0A3R7PTP2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone-lysine N-methyltransferase ASHR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024503</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000845">
        <property type="protein sequence ID" value="ROT82329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTP2"/>
    <dbReference type="STRING" id="6689.A0A3R7PTP2"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="45"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="50005" checksum="3B3992968010CE38" modified="2019-04-10" version="1">MRDLISVRALSALQKKKRLVKRGDEILTSKPFCFVLENSVIGQYCETCLATARKERLLSRCKGCWRAWYCSDICRDLGESQHRHECQLFRDRPDYRPRDFARFLARLIRKLKDGGEDVVERIDARRSRRFRDLMSHSKEIEKDQKRLDYLAEMMPDLQVLLGKSNIPDREELIQIFGKVHISYLDTMNSREHRRTFLQDNYYFTCDCRLCRDERHARTASSIKCRSRACGAPVHVDESGTGWVDPCGACGFCKFPRGVAYEYIEVADYTRAELADLDEDNPTGLEVWRDVAEAQGALLHPLNLWRSKSLEALVTASVNMRQWSAALAPARENEAAIRHYYGAKHPYVGLYLMKLAKIELNNMEWHPALEHLQEAEEILEAGLGSNHPLVFVDLAWLLIQASEECRVDIQRSLMYGRAQRTSSGGRSLVANRGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUQ9</accession>
    <name>A0A3R7PUQ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000727">
        <property type="protein sequence ID" value="ROT83154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUQ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="44548" checksum="B7A8472FC42B98EE" modified="2019-04-10" version="1">MQGEEEVGPGGQQTGLERPPSPTARRPLLKITSFAIVEVSRARNGCKACDFWFSFPDLNADLPLHNMLLDFFEELHLTNDTPPGAPTDRTQNRTAASNTERELSITLVRGAPSKGAPDAEAAPSAVETESCSTQQQPVGSRDSAPHRSTHSMVSRAALSLSSSWSPKSRRAATRVTPADAEGPAQGPRVRRTPAPRSTCAVEFTHGPSQRAPCSATHLTSALATLQLFRRCSLRSAQPLATYDTPRSGLRRHHARPRCTRPSTLPWRSHGDDEDPGGGREKEILTEEWRRGGLRSDAETVHFFKPPLPFLRKIDQRRSMHVRGPFRLAFSLFSPSLFSLLSCPPTSTTSFPPAFLLSLFSSFTSISSLSSSPCLLSSISSLLLPFLPFSTTPFLLSSPLPPPPRVLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PW40</accession>
    <name>A0A3R7PW40_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002402</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001316">
        <property type="protein sequence ID" value="ROT78898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PW40"/>
    <dbReference type="STRING" id="6689.A0A3R7PW40"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="3">
        <location>
            <begin position="78"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="367" mass="40495" checksum="4BE3BD6382F6C544" modified="2019-04-10" version="1">MPSRSSKEASRAFRLKGASGATLEMPECLSYGFNTPPNYNDHEIYCGGYARQWEKRREVRPPRDNEGGGKYGRGVIVKKYKHSSIVNLGVQLTANHMGFFEFRLCPHNQPNKPVTNECLDQNVLQKADGSGTRYYPGPGAKTFYSRYRLPLGLTCKQCVLQWRYVAGNNWGKCENGTGMVGCGPQEQFRSCSDITITEEDGYADETPSYVPDYDDYNEVDTETQEGLPKVPEDTANHVGHIVALTLSFLLVVLVLFGLVVYFYWARDAFKGFMKSQAGRWSKTPPPVPTSAPQKSSIITISGPIGAPPPVPPRRQRSVSGGEPALNSDQREIRSISAPTRVTINGIAVRPSGADNGISQARLHVPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZQ3</accession>
    <name>A0A3R7PZQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">At-cadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_024550</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000849">
        <property type="protein sequence ID" value="ROT82285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZQ3"/>
    <dbReference type="STRING" id="6689.A0A3R7PZQ3"/>
    <dbReference type="OrthoDB" id="6352190at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034332">
        <property type="term" value="P:adherens junction organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016339">
        <property type="term" value="P:calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044331">
        <property type="term" value="P:cell-cell adhesion mediated by cadherin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007043">
        <property type="term" value="P:cell-cell junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF422">
        <property type="entry name" value="CADHERIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="88"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT82285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="272" mass="28140" checksum="958540E096372670" modified="2019-04-10" version="1">MESAAPFPRSFSQGGQQEVEYQLRGARGALAVSADGTVTLRGALDRESSDGGVVVAEVLAVDRGSPPLTASATLTVVISDVNDCPPTLATPTVIHVQEHARTPALLATLTADDEDVWALGHGPPFNLSLAPGNPAHVLDKVDLKFNPYLDSGRGGAEVWLVSSADREEHRTLQVGVTVSDAGGLAATYFLTLIVDDLNDHPMKPASKTVYLWKTQDGGSDAPSAACTCGGPRRLGPAGQGLPVEGGAAPALLARRGLGGPLRLRSGTTWPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q0D7</accession>
    <name>A0A3R7Q0D7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003096">
        <property type="protein sequence ID" value="ROT65341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q0D7"/>
    <dbReference type="OrthoDB" id="7715894at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="137" mass="15584" checksum="E8E735E39B3838D6" modified="2019-04-10" version="1">MAFHEIGGKCYFYGYFPLNWYRASEFCHSFGKGVSLACIESAKENFHIKQWLGVNGNHNTGVWVGGSDNGHVGRWAWFPTGQLVSYSNWGPSQPSGGDQHCMYLVGGLLGYQWADFHCDFDMHFLCEYGVNDLEPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-09-13" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q0Q3</accession>
    <name>A0A3R7Q0Q3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000755">
        <property type="protein sequence ID" value="ROT82970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q0Q3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018597494" description="Ig-like domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="30365" checksum="54AE045A94A9F988" modified="2019-04-10" version="1">MGVRDKKGLAVPLLFVLVRLVLAQAARVSDYGVSTKLHIVNGTESIVREGESNFVFCYAGVRNLRGRAPYTVVWTDPWGRPLLPLPGISLNARLFSVRENELRPNAYMVFQMFDEDLEGVYTCNLVFKNRLVSLRRIRLKMFRPSYRVVTLAPCLAVQEGGSALLPAPVVGSPPAPPVWSKAGGSLDPSEAQVVQAGLVLHAVQEPGVYRVQVPLGGGLVHQQETVVAVVRIDGRKDFPSDATSAATAGPCPPWDATKPTERSDSVSVANDVIADIQMHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1Y8</accession>
    <name>A0A3R7Q1Y8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002947">
        <property type="protein sequence ID" value="ROT66370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1Y8"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1Y8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="42565" checksum="D641E894E1686FD5" modified="2019-04-10" version="1">MEAKHYISPFPLPPLLPLLPTFSLTSSLYILLPFPTLAISYSLLPYSLTFSFLLPILPFLLSFSVILVSFYSLLILSPVSLSLFALFPSIPLFPLSPPFPSSVSLPLFFLSPPFYPFLSYHYHSPFFLPPFSFHPPPPFPSIPYLYSLLFPLFLVPSPLSYHSFSLSLFSTPFPSSPSLPPIISSPISLFSPSFSLRFFPLPSFPLFFPINPSILPVSLFPLLTPPIPLFPSSYPSKLPSFSIPSAPPPISPQPPALTLPLSPPYLQLFPQPPLSLSPPRPFLFFPLTLPTPRTPLTVLSSSPCYTIPLTSPYHHLSPLSPSPRPTLTLPSHPLPTLPSPCLPSLPLTPFPPLPYPSFTLPSFPSPSPLPTSSPPLPSPPPLPPGPPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4S9</accession>
    <name>A0A3R7Q4S9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium-dependent dopamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002944</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000014">
        <property type="protein sequence ID" value="ROT86086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4S9"/>
    <dbReference type="OrthoDB" id="10507223at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF295">
        <property type="entry name" value="SODIUM: NEUROTRANSMITTER SYMPORTER FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018549964" evidence="12">
        <location>
            <begin position="27"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="399"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="472"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT86086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="611" mass="68941" checksum="1216314CA2B7A231" modified="2019-04-10" version="1">MKLWHSCRFAFSSFFFFLALTPSVKGPHEGSVSTSWRTMADVELHPLEPGTDASSPPPACPDKEGCDDDGDGDGDEKAETWASPLDYLPMLLSVVVWELGFLQFPYFWYINGGAFLLLYALLLVLLGIPLLLLESFIGQFTSSNCIEVFSFIPAFKGIGYSHGLFLLLMTPYMVVYTSYSLFHLVYSFISIEQWNLCGGEWDSEGCVPEVTDMWNKTENYLDFPSLALDMPWRFLPAVFVTWVVIFFALFGGVRVLGKLMWVTAGTSIVLLLALFIRGATLSGAWLGVGDLFRLESYMLTDIRTWTYVVNRVFNSLNLGIGITTTMASYNKVRHNVVRDVLVVSAVKVALEIVVGLAVICLLQYLADRMQLPLIDVVDMGLYLAYKTLPAVFSLMPQPLLWTCVLFVLVFFLCIPFMVVSVQVLLECLLTLLPPRWRRRRWPLLLAVCGAGFLLSSLCCFEPGRYINNMIDWGLGIVGPKILCLLVVIIFAYVYGAGSIARDVEMTSNKTISYYFYFTWISVTPLILVILSVGLSTYIFDFYIPPLTRVVACYFLPVVVIYSLCYVFRDDCCKKLQFKAKPWGPRAAGDRAAWKRFCSEHPVRNSLVHRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QA34</accession>
    <name>A0A3R7QA34_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020853</name>
        <name evidence="8" type="ORF">C7M84_020854</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="6">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004200">
        <property type="protein sequence ID" value="ROT61372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01004200">
        <property type="protein sequence ID" value="ROT61373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QA34"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000001">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000003">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000004">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0041">Annexin</keyword>
    <keyword evidence="3 6" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 6" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="320" mass="35700" checksum="2C967B20A5E01B21" modified="2019-04-10" version="1">MSSLLPQEIPTVSAAGHFDPSSDAAALRKAMKGFGTDEAAIIAILSRRTSDQRQQIMLKYQQSYGRDLVKDLKSELSGKFEDTILALMTPLPLFLAKEINHAIAGVGTNERTLVEILCTRDNASLMLIKNAYYQHFRKKLEEDLHGDTSGDFRRLLISMCACARDEASCDPALANNLAQQLYKAGEGKMGTDEAEFNRILSAYSYPLLRCVFEEYRKIKGKTFGDAIDSELSGDLKLGMKTIYQCIENRAAFFAKELHNSMAGAGTNDRALIRLVVSRSEIDMGNIKQEYQKLYKKPLEKDIKDDTSGDYKRVLLALVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAI3</accession>
    <name>A0A3R7QAI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein S13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008714</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002094">
        <property type="protein sequence ID" value="ROT72879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAI3"/>
    <dbReference type="STRING" id="6689.A0A3R7QAI3"/>
    <dbReference type="OrthoDB" id="623277at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT72879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="12308" checksum="86D3ABAB0197D038" modified="2019-04-10" version="1">MKIFSSPGVLLRDSHGVAQVRFVTGNKVLRVLKAKGLAPDIPEDLYHLIKKAVAIRKHLERTRKDRDAKFRLILVESRIHRLGRYYKSRAVLAPNWKYESSTASALVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QB64</accession>
    <name>A0A3R7QB64_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative glycine receptor subunit alpha-4 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_008077</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QB64"/>
    <dbReference type="OrthoDB" id="9990982at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="738"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="804"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="857"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="12">
        <location>
            <begin position="28"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="484"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT73412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="881" mass="101574" checksum="C8139F08217878B9" modified="2019-04-10" version="1">MPASSTFIPGITLVVMSTVLILVLAQNDTENVRLPEPDEVSHVKFQTGKYDTVDSYMDNSTGFPTLTKFSLCVHIKYHHMALNNTLLSYFASGQDNELSFFTNSMDANTLQLYCCGDRVRNYLYYPIRMYTWEHLCVTVNLETKLITVVLNNDVREYTVQETKSDGNETKPLVIRGGGRLVLGQDLDSADGGFNIEQILPCEIADFAIYDVVLTLDEIRSFMACDNQIPYEPILYIDQQMSVLKAVGETAVSYIPEEEICATSSGYKLMFPERVTFWGNVAWCQMLKGTVILPKNEKENTEVYDKFFPYREECTDRWRTFYYFGTVRNVTTDKWFHYKDKSPIVYQKFDVQWNKIVSQYECAAVGNHLFKYTWFAIPCSSAMCSACNFTSSPRLRVRGLCDTSILDSAYYLNDYYNRRPLFDGEVHSRIFWSNNIWELRSRRHEDLSATMETKNSKVYPLGRHTWTIAGDKCTESKITLLMTPCNSDEYTCSTGSCIRKTSRCDLVIDCPDQSDELNCDVVNVPEGYSSTLPPPKITKDPLALAFSLRIITIRKFNLVGFSLVVDAVMSIKWRDSRLTFRNLRRNYRVNKVKDMYQLWTPKILVRDGSRSAADVQLRSEAVYVILEDSPLPDDITIVSEDDRYSGSNNTLVMETESTLEFTCQFQLQMYPVDRQNCFLLFTLPGLSKDFGLLIKDEDGVTFEGSRYLLEYELVGETLTEEMEGRFSLMQIRLEFRNLYGYYIGNTFVPSLFLVIIVYLTLYFDINDFEDRVMVSLTSLLVLATFFTQTSSSIPRTSYLKLIDAWYVALICQNFLVIVSLVVVENLRLRDKPMTTRVTPMGVKSYEGDEVLLYKKVNFFLKFVFPLMLFGILTSFFSFWSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHD7</accession>
    <name>A0A3R7QHD7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative choline/ethanolamine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHD7"/>
    <dbReference type="OrthoDB" id="422540at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681:SF1">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="75"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="347" mass="38495" checksum="6FFB13518E9D011F" modified="2019-04-10" version="1">MIPLIEGQTSLSLERVKIPNSATTCSAMSPSATHDHTSRLPSAGDSSTHTTSIEASGPPNISAAKSSGLASTKTFDSDERFQHIHIDIVGPLPSDDGYSYILTMIDRFTRWPEATPIRDITAATVARTFLSTWISRFGTPDTVTTDRGAQFESELWRQLMVLLGSKRIRTTAYHPCANGMVERLHRHMKQALTSSSSNRRWVDQLPHVLLNIRTSFKEDLQCTAAEMVYGTTLALPADFIVTAGNFEPGTFGKQLCERMTRVRSRPTRPTRQQDIYMPPGLQDCSHVFSDKTITIRRPKGEDTVTVDRVKPAHLHQPIKIAKVRFATAKLEGSAVAVPDWPSIENHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKJ8</accession>
    <name>A0A3R7QKJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002437">
        <property type="protein sequence ID" value="ROT70369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKJ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="46289" checksum="8B28A85176C27ED6" modified="2019-04-10" version="1">METPARPPPQPPFSTLSDGHDAGYEGGFGEGAAAGGGWGAGSGWGGAGSGGGRREGGGRSEGASGDEGGETRGERGVGRGVEGKEGGGRGAIGRASGDEGGETRRGGREREKNQRVGRPLPAALTAPQTTFSPRYGKTAPLPLPLSPSLPSLPFFLLSLSLLSPSSISPLPFSPPLPSSSSFSPPPSLPFFILSPSPSLPSSFSPPLPFLPFFPSLSLSFSSPFHLPSLLSPFFHLFLSPPLPLYPSSSFPFSPSSFSPSLLSSLSPPLPFLLFLLSPSPPFLLSLLPLWQVSPSPPSPLSSPLSLPPSLSPFPSLLSLLSPSSFLIPFPPPAPSPLLSPIPSKSPSPPLNSPLTPPPLVSYSPPLLPPSPLPINRPLPSPPLPLPSSPSSLATSPPPFPPSFPSPPSSSIPPFPYQPFLLTLPSLACLPPSSLLLPPLPRTASPATAPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPW3</accession>
    <name>A0A3R7QPW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative bric-A-brac</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007308</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001924">
        <property type="protein sequence ID" value="ROT74191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPW3"/>
    <dbReference type="OrthoDB" id="6356924at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF98">
        <property type="entry name" value="PRE-LOLA-G, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="32"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="265" mass="29670" checksum="077FE2AA9CA5EB75" modified="2019-04-10" version="1">MFSSDKVKLRWSDHSSFFAKGLAPFLEEEAFHDVCIACCDGTTLGANRLVLSICSQFFRQTLTLCKEMRPTILLPDTSAEDMMALLEFMYRGEAYVTEERVPYLLMAARKLQINGLGVASPPQTSIPVEPEMTPQLVASDLTDGERHSMLSTPTSTQLCSTPGLPSPQQTHSPTPVSTRSRSVKSSSQDRVECETCHRLIFSTSMYQHKRYHHGPLRDPASCCGQTFITRWDLNVHRKTSPNHNEMLPEAISSPEEPLIMNESES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QSH4</accession>
    <name>A0A3R7QSH4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RPB6 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004818</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001636">
        <property type="protein sequence ID" value="ROT76599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QSH4"/>
    <dbReference type="STRING" id="6689.A0A3R7QSH4"/>
    <dbReference type="OrthoDB" id="259769at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.10:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020708">
        <property type="entry name" value="DNA-dir_RNA_polK_14-18kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028363">
        <property type="entry name" value="RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006111">
        <property type="entry name" value="Rpo6/Rpb6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002207">
        <property type="entry name" value="PRK01099.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002208">
        <property type="entry name" value="PRK01099.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500154">
        <property type="entry name" value="RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000778">
        <property type="entry name" value="RpoK/RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="RPB6/omega subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01111">
        <property type="entry name" value="RNA_POL_K_14KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="130" mass="14828" checksum="E1565525DB3B2086" modified="2019-04-10" version="1">MADEEFDGDDVGDDFEEAEEDENLDDLQEGEEDENQMEILAAGEGNQVPTQKRITTPYMTKYERARVLGTRALQIAMCAPVMVEIEAESDPLQIAAKELRERKIPIIIRRYLPDGSYEDWGIDELIISDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWG5</accession>
    <name>A0A3R7QWG5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc finger CCHC domain-containing protein 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TRAMP-like complex RNA-binding factor ZCCHC7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_000511</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001074">
        <property type="protein sequence ID" value="ROT80753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWG5"/>
    <dbReference type="STRING" id="6689.A0A3R7QWG5"/>
    <dbReference type="OrthoDB" id="6342085at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="11">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00043023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT80753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="422" mass="47249" checksum="7E6A3C3729D520E2" modified="2019-04-10" version="1">MASFYDSDVSEDLQIEAVHKQQSNSLRDWHINASDYPVYQRGRYFTREVRCTRCRQFGHLEKDCPRVPHCHLCSQTGHTVRYMCPENCCFRCGGEPHGFCYNTSAAVRCHLCGFHGHQMQMCPDLWRRFHITTSGEEVQSPEFHKVRPLKEQYCCICAKQGHYSYICPHRHENSYYSQVPQTVISYSSPVLQENGKLTVSAGAEILEVPADVTKFSVKQRDAGRLIGRQGMVVKEVQKLSNAKVIINTKYGRCQVHICGSWKDRKLAKGIIEVLLGRIPVAHGGLRSRPEVLADAGSDPSGLATMMKAKQALACGLRCRPRRSLRNPALSSARLKKLGEIEGQVRSSETASPDIAPAHYGKAIGKGGARLKYIHEKYQVRVSVPKDKESPIAVSGRSGSVRGAIKSWGARPADVLKQRVFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVL0</accession>
    <name>A0A3R7SVL0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004099</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001545">
        <property type="protein sequence ID" value="ROT77279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVL0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="60730" checksum="33EFFF4B46DBD491" modified="2019-04-10" version="1" fragment="single">GSFARTRRNSPSKGFFCESQLSFQRVLFFLRVATLLPKGSFCEISFASQLSFQRVLLRDFRVAKGFFCEVSFASQLSFQRVLCEVSGRNSPSKAKGSFARFPSCRNSPSKGFFCEVSFASQFQRVLWSNSPSKGFFCEDFLRVATLLPKGSFARFPSCRNSPSKGFFLRGFLRVATLLPKGSFAFLRVATLLPKGSFARVSFASQLSFQRVLLRGFLRVATLLPKGSFASLVSPSKGFFCEVSFASQLSFQRVLLRGFPSCRNSPSKGFFLRDFPPRRNSPSKGFFCEISRRVATLLPKGSFARFPFASQLSFQRVLLRGFPSCRNSPSKGFFCEVSFASQLSFQRVLLRDFLRVATLLPKGSFARFPSRRNSPSKGFFCEISRRVATLLPKGSFARFPSRRNSPSKGFFCEVSFASQLSFQRVLLRGFPSCRNSPSKGFFCEISFASQLSFQRVLLRGFLRVATLLPKGSFCEDFPRVATLLPKGSFARFPSRRNSPSKGSFARFPSCRNSPSKGFFCEVSFVSQGTHALDTHSVQEHSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0M5</accession>
    <name>A0A3R7T0M5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosrestin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000564">
        <property type="protein sequence ID" value="ROT84307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0M5"/>
    <dbReference type="STRING" id="6689.A0A3R7T0M5"/>
    <dbReference type="OrthoDB" id="6500995at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF17">
        <property type="entry name" value="KURTZ ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00309">
        <property type="entry name" value="ARRESTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="191"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="351" mass="39484" checksum="988D7724D1C476C2" modified="2019-04-10" version="1">MVVKLQVFKKSSPNSKVTLFLTKRDYVDHVSHVDPIEGVLVFDPSCVQERNVYVQIALSFRFGREDDESMGYNFTKTMYLHTTQLYPPVKEFVPSEIQRNLISKLGNFAFPFLLDFPKLSSPSYVMQQGWEDEGSLMGVEFEVMGYIGATEHDMPKRSTARLLIRRLQECPKALYEAPVPRGSITKSFLTTAGNVSIEASLSKPVYEPEEDIPVKIAIRNDTNRDIKRLKMKVVQLSEVPMFSDRQTRDKTIIKYDDPINLAPGACTTRGVTLMCCVPSRTARGKVFLQGGLRADCDDVIAPTTILNPEVDKNDVFGVYVSYVVRVKASLGTLRGDCILDIPFVLAVPQEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9D3</accession>
    <name>A0A423S9D3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004534">
        <property type="protein sequence ID" value="ROT60821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9D3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="417" mass="46662" checksum="59BFE988CC126A15" modified="2019-05-08" version="1">MFASIGLLLSSLFFLLFYLFSLLFFTFLLPFLVPLSALSITAFSFILSLLYLLNPLVSVSFHPFLLPPYLFLFYLRSPLSSVSYPLSSVSFPLSYVVTPLSSCLITFLSSLISPLSSLSHFPSLLCLIFPLSHLSYFSSLFSLVSFPLTLLSRLISPHSSLSSHFSSLLYLISPLSYAPFPLTLCLISPHSSLSSHPLPSFFPCAIPIYSPFLSLPFFFLFLFSSPLSLFPSLSLYSLSPFFPFLFFPSLPLFPLSIFPFPFFPSPFIPSFPSLPFIPSLHFLSFFPLSPFIPSFHFSLSFFPPLSLYSLFPFSLSFFPLSPFIPSFHFSLSFFPPLPFIPSLHFSPLSLYSLFPFFPFPSFPLSFLSSQYHLAIAAVSCSSSPINIDCHIVPCPVGEASRVGRPLRHVWLQLTSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBD5</accession>
    <name>A0A423SBD5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Protein CBR-GLR-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_020716</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004133">
        <property type="protein sequence ID" value="ROT61506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBD5"/>
    <dbReference type="OrthoDB" id="6382689at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF38">
        <property type="entry name" value="IONOTROPIC RECEPTOR 100A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="13">
        <location>
            <begin position="294"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="196"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT61506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="42309" checksum="AFCEB619DB38736E" modified="2019-05-08" version="1">MAVFLYLAQADNTEGNLKVESQSLFVSDFVAFYGIKHVCLVGEEETNKSGVKAISLIAGSAPLSYFSIIKTGIGFYRQDQQLSTSVNNVNITTQTIMSAISSCNGLIVFNLATATDQELFKKLFRGSDTRKRWLLISNRRFHELLKPVYLPLNNKLTVANFSQDGSSASLWESYQVDPQFPQRVVHVGRWTNARPSSTHLTFTPPHSQSHSPLSNNSQNQIQNDKEEPVSEKEGGAETGNKASFTIHSTVSNGVEVRTKHLRFGVLEAPVDDPHLRRQDLTGVHLRCTTMQLPPMTMLENNIDGSVTVHGITGKFFDTMKSIMNFTYTCHAVKDGQFGAFVDGEWTGMVKEVIQGVANISVGNLAITQQRNSAVDFLIGTISAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDW2</accession>
    <name>A0A423SDW2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019778</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003703">
        <property type="protein sequence ID" value="ROT62386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDW2"/>
    <dbReference type="STRING" id="6689.A0A423SDW2"/>
    <dbReference type="OrthoDB" id="283091at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="11761" checksum="7B41AE5C8A81965B" modified="2019-05-08" version="1">MGRTAMGDVQKGKKLFVQRCAQCHTVEAGGKHKTGPNLHGLFGRQTGQAPGYVYTDANKSKGITWGADTLDVYLTNPKKYIPGTKMVFAGLKKKGERADLIAYLAEATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEG1</accession>
    <name>A0A423SEG1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003621">
        <property type="protein sequence ID" value="ROT62595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEG1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="467"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="527" mass="59195" checksum="FF30561821DA1690" modified="2019-05-08" version="1">MDPSFHLLFLARQLFSLFLSFLSSLFLSLLSSLFLYLLFSLFLSFLSSLFLSFLFSLFLSLSCFLSSSLSCFLSFSLSCFLSSSLSCSVSLFLSSLLFPVFSLPLSPVFSLPRFPVFSLPLSRPCFPLPLSSLSSLFLSFLFSLFLSPFPVFSLPLSLFSLFSLSCSSLSSSLSCFLSSSLSCLLSSSLSCLLSSSLSCFSLSRFLFSLFLSFLSSLFLSLLFSLFLFLFLFSCFLVLSFLSLLFLSSLSLCFSSSSLTSLPLFLSSLFFSSCVLLFLSFLSSLFLSFLSSLFRSFLCSLFFSFLSFSLSLFPVFSLPVFLVFSLPLSPVFSLFLSLLFSLFLSLPVLSFLSFPVFSLLLFPVFFCLFPVFSFPFRLSCCLFSSVFVSFLSSCLLFRLSFFFLFSLSSFSLVFSFPVLLSVFLSLSLFPVLSLPLFPVFSLLLFPVFSLPLFPVFSFPLFLSSLFPLFPVFLFPLSCFFFLPLFSYFSLFLSFLLLLSSFSPPVFSFPLWLFLAFLFSVCLCVWVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHQ3</accession>
    <name>A0A423SHQ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uracil-DNA glycosylase</fullName>
            <shortName evidence="5">UDG</shortName>
            <ecNumber evidence="5">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_018392</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01003394">
        <property type="protein sequence ID" value="ROT63712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHQ3"/>
    <dbReference type="STRING" id="6689.A0A423SHQ3"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF7">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="8">
        <location>
            <begin position="169"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT63712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="485" mass="55782" checksum="B4B153F292D72629" modified="2019-05-08" version="1">MITRLSRLLRKNLIFGPSNNSPPPLFAHRREMATQKLIANFFKPVNKRVSGETQDTQVAKKPKIAEEKENAEEGNNAPGSPTRSSAPELNTCLSPEQKDRMQKNKLKAEIKQTSRKFGALHENIGTSWFSALKTEFSKPYFEKLSLFLDGERKRSTIFPPAEQVYSWTHHCELRDVKVVILGQDPYHGPRQAHGLCFSVQKGVPPPPSNRSQIGACLCVDRGLRRTEKTWRPRNIREITSPRYLGPQDFAIKTEFFLDVWAFSPIRPLLRHRAGSAMDTNVDWPSFDAYRRHREAPSYRGPLPKNRTPYLYVISEPLLSTPHQPRRRDSRYPDKRRARYRLPSRRFLLNMYKELESDIEGFERPSHGHLIGWAKQGVLLLNACLSVRAHNANSHKDQGWEKFTDSVIKAVSDRNKGVVFLLWGSYAQKKAAVVDKKKHHLLNTTHPSPLSAHRGFLGCKHFSKCNEILKKQGKKPIDWNYLPLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIA2</accession>
    <name>A0A423SIA2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_018152</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01003353">
        <property type="protein sequence ID" value="ROT63931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIA2"/>
    <dbReference type="STRING" id="6689.A0A423SIA2"/>
    <dbReference type="OrthoDB" id="2019940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF54">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="19942" checksum="466DFA8CC4E08214" modified="2019-05-08" version="1" fragment="single">ANLKEFLLPALLSNGLVFKDQDSDVWKNFLVKKKESFGKLDPEDERARLSVTFTEFLKHVANTFEEGRIDRHWKTYGLLCSPCFFDYEYIVKTETQDEDLEFVFGRFGFPSDPHRAKKLRGDLATKMARDFRYYETVPLEVKQEIYNIYKADMEMFGYDLPDDFWETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK62</accession>
    <name>A0A423SK62_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003237">
        <property type="protein sequence ID" value="ROT64553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK62"/>
    <dbReference type="STRING" id="6689.A0A423SK62"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="579" mass="60772" checksum="44048D414012B4AA" modified="2019-05-08" version="1">MYTVVTPTNTPFHIAPSPISRKTSTLGFLGRSSSLLAPGTPPPPLTRPASSSTWPAIYLYLLAIVHLLLIPPLPPTCAPPAPSTLLPSTVTYTSTYTLAPLHLCIHAPATYTCLHSTNLLHLHLPATVHGSTFLEPASTSPPPRCTSTCLAPPPALHGPSSLSRTCHLNHPLSTSRSTSCTLPPPRLALLPPPRHAPPTPPRQHALPPLRLTRPLLRSSAGLADRCLPTSTSTSTTSLHSLSPSSIALLTSTLHFHLPSRSLDSTPASTWPPPLPRLQRSLAPPTSATCNLPVHLASRPCSSPPPRSHLALTPPPPPPPATVAPGQPRAALHLGTCHTTSTLLPPSATSTLTHLQLFHLQPSTPRSSAPPACTCAPRTTFQPLLLIAPPTLLLQALNASAPRCTSTSCNLYLTLPLPPLSPPCSTSTCTPPPPCAPAPLLTSLHISSTSALLYSTSTRPARPPAACHHHGSPLAIPPSWQPALSTSSNLQLGTSPHAPLHLPASHPSLHLPLRAASPLPPLLYTPPPLTSTHSTLHRATFHSTCQPPPPPPPHLPPPRCPPAASSTPRSGGSQQRREKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK89</accession>
    <name>A0A423SK89_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="16">1.3.8.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">2-methyl branched chain acyl-CoA dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">2-methylbutyryl-coenzyme A dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">C7M84_017400</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="31">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="31 32" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="31">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>(2R)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = ethylacryloyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65296"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156439"/>
            <dbReference type="ChEBI" id="CHEBI:156440"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="22">
            <dbReference type="Rhea" id="RHEA:65297"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48256"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:88166"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:48257"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57336"/>
            <dbReference type="ChEBI" id="CHEBI:57337"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.5"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:43781"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>2-methylpropanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:44180"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62500"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:44181"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24004"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57332"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:24005"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>hexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:43464"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:62077"/>
            <dbReference type="ChEBI" id="CHEBI:62620"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:43465"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>valproyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-propylpent-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:65344"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:156457"/>
            <dbReference type="ChEBI" id="CHEBI:156458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:65345"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 27">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid degradation; L-isoleucine degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; mitochondrial fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 27">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.5" evidence="16"/>
    <dbReference type="EMBL" id="QCYY01003214">
        <property type="protein sequence ID" value="ROT64658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK89"/>
    <dbReference type="STRING" id="6689.A0A423SK89"/>
    <dbReference type="OrthoDB" id="10262177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003853">
        <property type="term" value="F:short-chain 2-methyl fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046395">
        <property type="term" value="P:carboxylic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01158">
        <property type="entry name" value="SCAD_SBCAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000012">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000002">
        <property type="entry name" value="Acyl-CoA dehydrogenase short/branched chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF1">
        <property type="entry name" value="SHORT_BRANCHED CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 27" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 27" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12 27" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="30">
        <location>
            <begin position="57"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="29">
        <location>
            <begin position="172"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="28">
        <location>
            <begin position="279"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00049096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00051903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="ROT64658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="433" mass="47320" checksum="863D0A2D2D2F0C58" modified="2019-05-08" version="1">MAATFGRFSKALVTSSRGFLRPRWLHSASGVGPWQQKNVPQLEETLGFLPSPLTVLSDEELMMKETVAKFAREQVAPLVSKMDEEGCYDPSLVRGMYENGFMAIETEPEYGGCGSTFFVANLVIEELAKVDPSISLLCDLQNTLFNTLFRKYGTEEQKQKYLPKLATEMTGSFCLSEAESGSDAFALKTVAVKDGSNYVINGSKMWISSAPQAGVFLVMANANPSAGYKGITCFIIDAGTPGLSIGKKEDKLGLRASNTCAVHFDNVVVPEENILGEFGHGYKYAIGMLNEGRIGIGAQMVGLSQGCLDATIPYLLQRKQFGKALFDFQAVQHAVAYLATEIECARLLVYNAARLREAKQPFIKQAGMAKLYSSEVATRVTSKCVELMGGVGFTKDYPVEKFYRDCKIGTIYEGTSHIQLNTIAKLVAQDYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN86</accession>
    <name>A0A423SN86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative homeobox protein Nkx-2.2a-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016407</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NK-2 homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003066">
        <property type="protein sequence ID" value="ROT65604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN86"/>
    <dbReference type="STRING" id="6689.A0A423SN86"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF24">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX-2.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="151"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="83"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="330" mass="35971" checksum="98CC93F51DB70E44" modified="2019-05-08" version="1">MYFPTETRYGSDLPSYPDADDSWSHPNLQDEFRLNVDRTRQTLPTAGSSNYTEPHNGFGSEGTTGRYCSSLWAHTTQETPDFNVGVDSSFPSGICSPHEVPNPPSLQPRTQDPTTETNPQPAFPQPSPHLSTSPLAIPDPRSILSQDASVRYLSAPEREHLASIINLTPTQVKIWFQNHRYKTKKQRTDRSVELGPLTSPRRVPVPVLVRDGKPVPVHHPPPPQFNTTPSYTPSFLDVGGYYQQATAHMRGIPTPSLPHSTYASMGMMSAAAAYNSPGLQGQYGSHALTPAVTSSATLHYAAPPTMAEAPDPSFAPAQYTAPGFSYSAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQ51</accession>
    <name>A0A423SQ51_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Bip</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_015661</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002959">
        <property type="protein sequence ID" value="ROT66321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQ51"/>
    <dbReference type="SMR" id="A0A423SQ51"/>
    <dbReference type="STRING" id="6689.A0A423SQ51"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000153">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000029">
        <property type="entry name" value="Heat shock 70 kDa protein cognate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="646"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT66321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="656" mass="72917" checksum="16D65A7F9250E1EA" modified="2019-05-08" version="1">MFSSVYCIDGLLNDTMRCWTALAAIAAVMAVAATAKDKKEEVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTADGERLIGDSAKNQLTTNPENTVFDAKRLIGREWTDKSVQHDIQFFPFKVINKNDKPHIKVSTTQGEKVFAAEEIRHGKTVTHAVVTVPAYFNDAQRQATKDAGTIAGLTVMRIINEPTAAAIAYGIDKKDGEKNILVFDLGGGTFDVSLLTIDSGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRSLSSSHQVRIEIESFFEGDDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLQKKEIDEIVLVGGSTRIPKIQQLVKEFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEDDTNDLVLLDVNPLTLGIETVGGVMTKLIPRNTVIPTKKSQIFSTASDNQHTVTIQVFEGERPMTKDNHILGKFDLTGIPPAPRGVPQIEVTFEIDANGILQVSAEDKGTGNKEKITITNDQNRLTPEDIERMIKDAEVFADEDKKLKERVESRNELESYAYSLKNQINDKEKLGAKLSDEDKEKMEEAIEEKIKWLEDNPESDAEDYKTQKKELEDVVQPIITKLYQQSGEAPPPTEDGEDYEKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SU98</accession>
    <name>A0A423SU98_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SU98"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="554" mass="60045" checksum="BB602A2901BAF2CD" modified="2019-05-08" version="1">MDEKKHKKTTLPPFPSPLAFESSLPPSILSSTPSLLPFQSLSFPLPLPSSLFLPSASSFQRLSFPASLFSLRNSLSLPSILFFPPSPSPFSKPSRLFPLPSPLLQSSSFPLPPFSPFKPSFPLPSPSFKSFFSLLSLLLRVLSLPPFQSLFFLPSLLPFSSLSFPSSPPSSLSFSSLLPFQALSFPLPSSLPPSLLPFKPLLPSPSPFESLSLPSILSSSSLLPFKPFSFPLPLLLQSLSLPPSLSSSLPSPFQASPSLLPFKPLPSPSLPLPSLSLSLRISLPPSHPLFLPPFIFPLSFPLPLPSLIQALLLPILSSPPSPFQASSPSPSSLSSPSHLFKAFHSLHPLFLPSLLPFQALLPSPSLHPLFPSLLPFQPLLPFPLFLPPFSLSSLSFLSLSHGAWQLMIITTRGLPLPSNLRLHDRALLFAFSSPPPPLPPFPVLLLLLLLLTSFPPSPPPPPSSLFLSSFLPLPLPPSSPSPSSPFPLSKFFLSPPPLLPSSKFPPPRPSLLPSFPPLDHLLPRPPLRLRQGDDAPPGDTRRRRRSSPITKGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVB0</accession>
    <name>A0A423SVB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002717">
        <property type="protein sequence ID" value="ROT68118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVB0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="41268" checksum="AD1FCFEC64002D70" modified="2019-05-08" version="1">MKSICSTFTEAENINKTEAAVVTLSPGAVFRKTFSDAQESKFLKTSEEKEAALSQTSSSVDVLRRERIGEDLASGKERFSSLIPPSFLSYAFSFLFYSSPLPLVPPSISLFYSFLLFHSFRPSYTSLLLLSSFLSCFVYPSSLPILYFPTLSLHLLPFFPLSLSPPPTSLFSSLSPSSLSFPILTPSLSFPLPSPRPLSPSPLPTFSHPLLPSPTPSLPLALSHQLFSPSLSHPLLLSPTPSLPLALSHQLSSPQLLLTPSLPSYSFPVPLPPTPSLPLPSPTLSSSPCPSPPTLLPLTPTHFLPLPFPLYPLLPSPPPSHPSLPSPTTPSSPPSPNSSSSPRPLPTPCLSSFTHSHHSHPLLLPRHPPSNKLGVDAKDSPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVJ0</accession>
    <name>A0A423SVJ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002703">
        <property type="protein sequence ID" value="ROT68237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVJ0"/>
    <dbReference type="OrthoDB" id="6349430at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019269540" evidence="1">
        <location>
            <begin position="18"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="138" mass="15332" checksum="01CD06DA8A950309" modified="2019-05-08" version="1">MKAVLLLVALSLGLASGEPAWCTCAPFVSFEHSEIMVYNSHETTINDCVNDVIVCRNYCTNYFGTTTNNGDLWFYTSGNTVGGHLCDYVFKNDLMPFLMHKTVHGYYQVCGGAWRYGEVSSSEALCCELGEQTHCTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXG2</accession>
    <name>A0A423SXG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative L-rhamnono-gamma-lactonase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002624">
        <property type="protein sequence ID" value="ROT68879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXG2"/>
    <dbReference type="STRING" id="6689.A0A423SXG2"/>
    <dbReference type="OrthoDB" id="6364264at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052350">
        <property type="entry name" value="Metallo-dep_Lactonases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569">
        <property type="entry name" value="AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43569:SF2">
        <property type="entry name" value="AMIDOHYDROLASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="3">
        <location>
            <begin position="147"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT68879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="27694" checksum="F16DAAD9E2E45AE0" modified="2019-05-08" version="1">MADVGLDSHLQGPPCRGPVGGDGAFSRPRGRLRAVPQRLARRSHQNPRVGSCRLDPSHQQFESQLTALKKEVPILVGVRHILDLEPRPKYLELEEVAAGVRALHRHDMTFDLLLRPPLLEGATVPAECPKRGWWWITWPNPTSRTVSWTRGARTSPPSHAIPISSMVTEADCEKWKPEDLRPYVEHMIAVFGCDRLMYGSDWPVCHLARADYNTVFSTLRGLLGHLPEPQLEKIFCSNARNFYKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYH5</accession>
    <name>A0A423SYH5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Actin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012606</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SYH5"/>
    <dbReference type="STRING" id="6689.A0A423SYH5"/>
    <dbReference type="OrthoDB" id="6330814at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT69232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="43863" checksum="0F3AF643325BC8B2" modified="2019-05-08" version="1">MLSKGRGPRGTSTLINHRPTSDDEDLTALVVDNGSGLCKAGFAGDDAPRAVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWYHTFYNELRVAPEESPTLLTEAPLNPKANREKMTQIMFESFNVPATYITIQAVLSLYASGRTTGEVCDSGDGVTHFVPVYEGFALPHAILRLDLAGRDLTHYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFESEMNVAAASSSLDKSYELPDGQVITIGNERFRCAEALFQPSFLGMESAGIQETVHSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILSSLSTFQSMWITKDEYEESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYS6</accession>
    <name>A0A423SYS6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear transcription factor Y subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CAAT box DNA-binding protein subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Nuclear transcription factor Y subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012349</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SYS6"/>
    <dbReference type="STRING" id="6689.A0A423SYS6"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000110">
        <property type="entry name" value="Nuclear factor Y, subunit B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF9">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="12">
        <location>
            <begin position="49"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT69456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="188" mass="21106" checksum="7993F7E409435634" modified="2019-05-08" version="1">MEGAESDDIGASFLSSEQYMVEGHVGHGHQHDDEDKEDLPHLLREQDRFLPIANVARIMKKGIPKTGKIAKDARECVQECVSEFISFVTSEASDRCHQEKRKTINGEDILWAMNALGFENYVEPLKIYLQKFRESTKGDKPLDNTLESAYEVDFGNNMTTFATEHVSQSDIVCTYGPAGQVSQQFTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZI3</accession>
    <name>A0A423SZI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative CBP80/20-dependent translation initiation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002548">
        <property type="protein sequence ID" value="ROT69589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZI3"/>
    <dbReference type="STRING" id="6689.A0A423SZI3"/>
    <dbReference type="OrthoDB" id="565552at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008494">
        <property type="term" value="F:translation activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051367">
        <property type="entry name" value="mRNA_TranslReg/HistoneTransl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23254:SF16">
        <property type="entry name" value="CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23254">
        <property type="entry name" value="EIF4G DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019248366" evidence="1">
        <location>
            <begin position="30"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="303" mass="32882" checksum="782EAE95E5D64BDC" modified="2019-05-08" version="1">MTKRMRNSETPAGLLLLTLLSQCCQVCLKENSVNSLAETECLFFVLTGLGKDIEVELPHQMAKVMGAARDAFLTTVRVPAVRKTLLQLIEMHAARWQLPAPAVMYYYPGSGMYRRSHVETHGTRLPVKHVPRQRRCALGERPLFLVKPKALLCAPEGGMSYSDSFNDRPTLIKRFSILLSSDSPCGKARAVILKVMKWPAGGKEKPGGCGCSPRCSLDGSSCRELTRLTAYKVPTLAGSETGFSAGVAALSMWLKGGHSNCSLLYTPGPSPAVPMSCSPPFPPNPAVSCDQLRSSSRKDPTPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1J6</accession>
    <name>A0A423T1J6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002437">
        <property type="protein sequence ID" value="ROT70364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1J6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="525" mass="56406" checksum="A7EE7320BA208401" modified="2019-05-08" version="1">MLHVCQYVGHIEEPFKLLGLRGFQFGSFWATSVAPSSSGSSSWATSVAPSTSSGPPPGRPPWLLPVRAPPGRPPWLLPVRAPPGRPPWLLPVRAPPGRPPWLLPVRTPPGRPPWLLPVRLLLGDLRGSFQFGLLLGDLRGSFQFGLLLGDLRGSFQFGLLLGDLRGSFQFGLLLGDLRGSFQFGLLLGDLRGSFQFGLLLGDLRGSFQFGLLLGYNKYEADVARVRTPPGRPPWLLPVRAPPPGRPPWLLPPVRAPPPGRPPWLLPVRLLLLGDLRGSFHQFGLLLLGDLRGSFHQFGLLLLGDLRGSFQFGLLLLGDLRGSFQFGLLLLGDLRGSFQFGLLLGDLRGSFHQFGLLLLGDLRGSFQFGLLLLGDLRGSFQFGSSSWATVASSSGSSSWATSVAPSTSSGSSSWATVASSSDSSWATVASSSDSSWATTSVASALTTILISQICLVSSVVHWTLASATSATYSYVKTRISAERRECSRLSGFRNDGGNVRVKFTLKTRSGPCGTCPGSDRIELIPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1Y8</accession>
    <name>A0A423T1Y8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-protein ligase E3C</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">HECT-type ubiquitin transferase E3C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">RTA-associated ubiquitin ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_011166</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Interacts with 26S proteasomes. Interacts (via the HECT domain) with UBE2D1 and, less efficiently, with UBE2L3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UBE3C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002412">
        <property type="protein sequence ID" value="ROT70559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1Y8"/>
    <dbReference type="STRING" id="6689.A0A423T1Y8"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000002">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000011">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000014">
        <property type="entry name" value="Putative Ubiquitin-protein ligase E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="16" id="KW-0436">Ligase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="6 13" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="15">
        <location>
            <begin position="733"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="13">
        <location>
            <position position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT70559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1071" mass="121384" checksum="7BFEB5BE2E063539" modified="2019-05-08" version="1">MWSFEGDYRRKPQQRLGGASRARNIERSDLLSQLKSDREERERQRRREAATLTIQSWTRGMLSRRKTKQELRQQCDSVLAQAKSQGITEPAARKLIALLIRIYNAKDDSERLLQTCQLVVVEHQRLSGWVCASFHQWMYLLPRLANMALVSVTSSHEGQSAMPHASPLRLLQILMSPDSWKTKLSESNKQIFLLSLYSYLISKDYYNQVVHLMVTRVPDIYEPSPVAPTALADALLQLLLSPVSFALSLDESTLLSSVIDELCQEIFGKASHTQISNYVIPCLASRENFKLPVDKIVAVLGSRSSKFLKACPAPPLLYSLLMLVRSNADFSDSHALCDYLQAISDLLGGTTTYLLSEVNDVDSDSDDDDTMDSTEAIDPILRKLAEECVTIVNSTEHVGWLLSHVERQVSPEVLLHFSRLTHHLLTAPSLQLHQCRLLYSVVARRQLLRSMWVVLSGLQQGAPLPGNANTTTWTFGVRGAPLLQVLARGTPLASHERDTLIPLLSTFCATLTAVLSTLHDSEFLGDQDETGEQRFPKTTDNHFPFTVEELIKMSASLRDVCVGLVELAHPDVRMSALTDTSYKTMWAHCFKVCVGVVRQIHLRDTRRMFCPKGHWLSTRVSLPLGNCQTVSFVPRTSRRQRRLFMPQRWLTRDELETEGPPLSITEQRRATILQELPFVIPFESRTQVFSNLVADNRSRSQMRADFNEGPMINVTIRRTHIYEDAFEKLSPSNEPDLHLRMRVRLMNAVGLDEVGIDGGGIFREFLSELLKTAFDPTRGFFLLTRENTLYPNPGSHLIAEDYQTHYYFIGRMLGKALYENLLVEVPLAGFFVSKILGRSSSSVEFHHLDSLDPELCRNLLYLKTYEGDVQDLGLDFTVLNSDLGQNTIEELIPNGSNVAVTNENRIEYIYRMADYKLNKQIAKQIQAFKKGLADVVPLEWLQMFDWRELQMLISGASVPIDLEDLMDNTRYGGAYNTEHPTIVAFWQVLRGFNEGQKRQLLKFVTSCSRPPLLGFKELQPAFCIQPSGSEDRLPTASTCMNLLKLPEYRDQQTLREKLLYAITSGAGFELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3F5</accession>
    <name>A0A423T3F5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 17">Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase</fullName>
            <shortName evidence="17">GNT-I</shortName>
            <shortName evidence="17">GlcNAc-T I</shortName>
            <ecNumber evidence="14 17">2.4.1.101</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15 17">N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_010728</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 17">Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11456"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="Rhea" id="RHEA-COMP:14368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60625"/>
            <dbReference type="EC" id="2.4.1.101"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="17">The cofactor is mostly bound to the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 17">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 17">Golgi apparatus membrane</location>
            <topology evidence="1 17">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the glycosyltransferase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.101" evidence="14 17"/>
    <dbReference type="EMBL" id="QCYY01002364">
        <property type="protein sequence ID" value="ROT70981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3F5"/>
    <dbReference type="STRING" id="6689.A0A423T3F5"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003827">
        <property type="term" value="F:alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.20:FF:000001">
        <property type="entry name" value="alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.20">
        <property type="entry name" value="N-Acetylglucosaminyltransferase I, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004139">
        <property type="entry name" value="Glyco_trans_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052261">
        <property type="entry name" value="Glycosyltransferase_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10468:SF0">
        <property type="entry name" value="ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10468">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03071">
        <property type="entry name" value="GNT-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 17 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 17" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 17" id="KW-0464">Manganese</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU368119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT70981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="339" mass="39310" checksum="87D9027F6C3E20C7" modified="2019-05-08" version="1">MEDGSVKSHNINQQLDKLEDELSKQSKFYSSLLEKLRGLQRQQQEDHHVSNEEDDFRVIKDGPVLPILLIACNREAAVRRSIDLLLKYRPDQDRFPIIVSQDYDLDVAPDFYEYFSATYPILRSDPTLWCVSAWNDNGKAGLVDVKNGSSILYRTDFFPGLGWMMTKELWDELGPKWPRSYWDDWVRAPEQRANRACIRPEVSRTRTFGKKGVSNGLFYEKHLKQIHLNEVFVPFTKLNLSHLHQEQYDPAFEKEVQNSQVVSLTEVKSGRLTQGVKYKIVYHTKDVFKRTAKALGLMDDFKAGVPRTGYKGVISFFYGNNRIFLAPGNNWQGYNPSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T521</accession>
    <name>A0A423T521_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative organic cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010074</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002275">
        <property type="protein sequence ID" value="ROT71597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T521"/>
    <dbReference type="OrthoDB" id="6894481at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="44306" checksum="A9598DBDDD13823D" modified="2019-05-08" version="1">MYMVGMLLGAITIGDLADRFGRKMGILVSVMLLGGGGVLSAVSPNYYMFLAMRLLTGAGGVGLFQVTFVLAVEFIGAKYRTFCGIMIEVPFALGEAMTGVLAIFIRDWRWLQVAVTAPAFLLLSYMWIMPESVRWAGCLKGKRDVAVQIIQEAADVSREVPKHLLEDSNTEVPTVDGSLSVASSKAELVKEDPGEPEPKVTKSVIDLLRTPNMRKRSVNLFYCWAVCTLVYYGLSSNSGNLGGNIFVNFIATMLIEIPSYVFSFLVLDRMGRKGTLSFVLLLGGVACFVSGFIPEDFGAVIVTLSLVEVLALVLVPCVLAANLGGIVAPFVASLAHTYKPLPLLVFGGLSIVAGLLVVLLPETVGCELPQTIPESERFGSDQSIWYFSCCGKKRSEPVTEENAATEDQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T606</accession>
    <name>A0A423T606_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002239">
        <property type="protein sequence ID" value="ROT71853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T606"/>
    <dbReference type="OrthoDB" id="6354779at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="294" mass="32248" checksum="56464662DF3F4888" modified="2019-05-08" version="1">MQSVEPRDGAVGLVLKIAQLEVSFGGDPEASGYKDIFYLFTAVAILTEERESRQDYELAYKEVVPEGWLSFRLEVAPDYRLYRKAKDGTQVLLFERSLALPVQEVVISGSNITLGCDADWYAWRVDGESVVVPLTPGGNQLVAVYSNSHFTPTLVLGSLNVTLTAEQKNARDVDDGKALPPYMSHEFTIECSVASAGVGDGVVCGVKREGEVFQRLKMPTLPATVTLEGSGQPQYFFLQQPEPLLVVHPPSTTRPVSPRPPHPSTTPMSVGAKQQCRSSLHGWGSNLLRDPWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9W1</accession>
    <name>A0A423T9W1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protoheme IX farnesyltransferase, mitochondrial</fullName>
            <ecNumber evidence="3">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_008312</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>heme b + (2E,6E)-farnesyl diphosphate + H2O = Fe(II)-heme o + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002046">
        <property type="protein sequence ID" value="ROT73259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9W1"/>
    <dbReference type="STRING" id="6689.A0A423T9W1"/>
    <dbReference type="OrthoDB" id="5211at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000004">
        <property type="entry name" value="Protoheme IX farnesyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448:SF2">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT73259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="56507" checksum="46B79984AE1D30E8" modified="2019-05-08" version="1">MVWAQGLKTLVLASQNSSIGLVRSSQAPLLAWKAGLRIFPHRKYVHNRNLSPSIYQLSGLQDRDGTEESVKEVPVTRANGNGQSSNIKVLLIDKSKALKSLTSRETPILHDAGAGAIVDVRTREQERESTSDEKNEAVEVRLQVTQLLKNSRASVKTASNLQPYNEDIEYIDEAKDRWSQKTELVGALKPEDLDWRPQKLNISKLGTYYAGLAKSRLTGLVVITAVAGYAMAPAPLDPSTLLLCSVGTGLVSAAANAINQICEVPYDSQMDRTKNRILVRGLISPLHAMCFAAVCSTTGIAMLYYGANGLAASLGAVNLLLYTCAYTPMKRLSIFNTWMGSVVGAIPPMIGWTSCSGSLEAGAWVMAGILFAWQFPHFNALSWNLRPDYSRAGYRMMSVTNPVLCRRVALRYSLAMIGICTLAPAIDVTTWMFAVDSLPVNGYLTYLAWRFYQDADSKSSRKLFLFTLLHLPAIMMLMIISKKHYNKKESKDSALGEGGQRHSERQELTKEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA99</accession>
    <name>A0A423TA99_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002028">
        <property type="protein sequence ID" value="ROT73410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA99"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="42872" checksum="6F0DD81023706D67" modified="2019-05-08" version="1">MRYVTLHVIRPIKGDGAPVQKLAGKNGGFGRILRERGGRGYRRWGSRKKQKEIEELGEMKLGEIVVYLGVVIIRYRIRDHVTHEKARRSGKLESSRHHAYFHNPDCHGIHSLASHPTFALIPELHLTLTTTHIAIHLLAHQHRNTPHTPTPSRTPPPPVAYSLTLTIAVCTLIHRHSTPHPHHHHHSSLHRHLNHHRHQSTTSPPPQSTPSPPQQSTPSRPPQQSTPSPSPQQSTQAPLPPPPPQQSTPSHRHSSLHHHHRHSSIHPHITTAVYTGTIATTTATASTPSPPPQQSTPPPPPQQSTPSHRQAALHPHPHITITTAAYTGPSHHHRHSSLHPHTATAVYTLTLTITTAVYTGTITTTRHSSPSPPHTVYTLTLTTATTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TC33</accession>
    <name>A0A423TC33_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001947">
        <property type="protein sequence ID" value="ROT74054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TC33"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019483979" evidence="2">
        <location>
            <begin position="18"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="59968" checksum="A6E44419CF91B796" modified="2019-05-08" version="1">MLLWHPLSLLLPTPILSSSSSSSFFPPSSSTHHHLIFLSPPTAYHHLFIFILLLILLSPFLLTHHHLPMGPDPSTPTNRCSSSGLLPSPLLTILHHPCPLPLLHHTFHHRILLLSSWFLPSLLLTIIKNHLPLPLSHSYRSFSNSSLLLFLLLLTIIIKLVLFSFLPSSLSSYSYSFPPLLHHPHLPPPPSPTIIFIILLFFFLLILTIIFLLLLVLPLLPSSSSSYSSSSPPLHPSSSIFLPTSYFIFIIFLLSFFLLLLTFIIIFLLVLPLLPSSSSSYSLFFPPPHHPSLLFLLPLLPSSSIIFFLSSSSSSSSPSSSSSVSSLSYHHLHHIIFDSSSSSFLTILLLLSSPLYHHHHSISSSSFLSPPPPPSSPTSLHHLLFLLLPSSPHSSSVSSLSYHHLHHLILILPPPPPPSSHHLPCPPTPTIIFIIFFFFLLLIIIIFLLLPLLPSSSSSYSSSSSSSSLPSSSSLSSLSYHHLHHLILILPSSSPSSSSPLTSSSSSSSLSYHHLHHLLLLPPPPHHHHRHRLHILFHSRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCD8</accession>
    <name>A0A423TCD8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001936">
        <property type="protein sequence ID" value="ROT74096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCD8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="744"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="796"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="761"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="826"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="873"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1047" mass="110716" checksum="C4615D741E6BEA72" modified="2019-05-08" version="1">MWVEFKPPSLPHTQRNEPPLRLRTPSAPSTTPPNSLLLVSELPPLLPLQTPSAPSAPLLYASKSSLPPLPPLPSKNSLPPPLASKLPPLPPSLSLRLQTPPLPPLTLQTLLIPPSISASKLPPLLSFTRLQTPSAPSAPFHSASKLARPPLPSTPSITPSRSAAILPPLPPLLHSLQTPLPPLPPLPPLPPLHSPPKLPPLLSHSLHSASKFSAPSSAPSTPSASKLPPLPPLPPFASKLLHSLHPLKLPPLLRSLHSAFQTPSALLLPLQYSFRSLTPPLRLQTSLRSLPPSASKLPPTPSNSAPLRLQTPSAPSLPSTPPPNSLPLPPLRSKLPPLPPLPPLASKLPPTPSRPSSPSTKLPPLLHSASKTPSAPSTRSNSPSFSPPLVSKLLRSPLPPNSSGSLLSLHSASKLPPPLHSASNSLRSLHAEPLPNSLRSLHSPPNSLRLPSDPHSASKLSSAPSTPPPPPRSLHYASKLPPLPRSSTPASINSLRSLHSASKLPRSLSSVPPNSLRLPPSTPSTLASKLPPLPPLPPIRLPITPSAALHFRLLQTPSAPSTTLQNLLPLPPLRLQTPSLLHSASKLPPLPPLPPLFRLQTPSAPSSLHSASNSLAPSAPSTSALKLPPPPSTRLQTLPPLLPLPPLPFPPLPHSLHSASKLPPLPPLPPLPPLTPSAPPLRLKLPPLLTRLQTPSASHRLPPLLLHYASKLPLLLHYASQLPSAPSFHLLPPNSLRSSNRLKTPLLHSTTPPKLPPLPPLALQTPSAPLHSLHSASQTPSAPSLLTLHSASTRLQTPPLRPASHSAPPLLHSASKLPPLPPLPPLRLQTPSAPSTTPPNSLRSLHSALRLQLPSAPSLPPLRLQTPFPPLRLQSSLAPSTPPLASKLPPSLHSPPLPPLPPTPSTTPPNSLRSLHYASKAPYLLCLQLPPLPPASKLPPLPPLRLQTPSAPALHSLQTPLLQTPFRSLRSLHYASKPTPSKLLRSRSLHYASKTPSAPPLPPLPPPNSLRSLRSLHYASKLLSLASELPPLLRFQTPVIKTTDSVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDV3</accession>
    <name>A0A423TDV3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_006884</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001875">
        <property type="protein sequence ID" value="ROT74612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDV3"/>
    <dbReference type="OrthoDB" id="6376404at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF63">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT74612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="358" mass="41199" checksum="1E285205589F8E4A" modified="2019-05-08" version="1">MTFISISRSPKKLLRNFLLAFLIIFAVRLKLSKQKEAAAGRAAEVTDEPRVEVLGNRAALRVKPKTEQWALEMEEVPLESVDLEEVGLRLEERRSEIRRRCERFLTSEELQEAPNSREFLINKDYGLVWCNVFKAASSTWLYNFLLLAGISKKVIERSRTSPVEVARTKAYPRPSVEELRAFVASANATSFLIVREPFQRLLSAFRDKIEANHQAHYRSLRCHIQTKVGRRSRRGVDCQPTFPEFVDYLLEERAKGHAPNEHWAPYYSFCSPCQVAFDYVLRFESLSQEEAFLVAKFHSGGGSGLSVCGRGVDYETATRHYFSQLSEARLLALYAIYKRDFEIFGYDATPYFDYAKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF10</accession>
    <name>A0A423TF10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT74995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF10"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019488453" evidence="3">
        <location>
            <begin position="18"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="633"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="867"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="995" mass="109330" checksum="9E5470BB2660B34C" modified="2019-05-08" version="1">MMLWTLPLLLTALSVTADPLPIRPPVVGYAGLISPMRQAVLLDPKDILDEVAMQGSEPALTTTPPGSAEVTPAGSASAPTASALFQASRSVRPILFSRSDNGTRKRIRRIRPRLQGLRRKTGSGTLLSSAGVRTAVSQAAGLARRRSGVAAGQSRWGNSQGILNPRTAQQGVPVPVKEERNKSSVDDFLTRWRKIYSKGHTTSPPSTARPHQAWNEAITKKPNMEANMPSPTSPPRHRERPPYSEINRYNPSQIMEAKHPFAPVAHLSKMPSIHELTSFHFSDSNKITQDQDSGNVMQNTPSSTTTTEVTTTTTTPPPTTTSVVLLTSPRTQRPFENVAQEREILESIQSIFQTVDRDGQKTPSDEVEPPPAFDIFADSEATKGFRPSLRLTPEVEVQNSYSVYEEQANKRVPSYDTSNLGSWETSDAYTTDNALAHNAGPTVLVSTPPPGSDLTLQVGHSLPVADHSSAMAQQREAVSSNGNIIVGRPAALIQPPMNTPGRIVDVPAHPHFREEPMYIHNPPTEPTQPSILFSPRPIWQPEELGPLLQYIESTYDPKLSQNSQPSVSHLQSMINSGQAPNVFVNDHLVDYIRSRPHSKIPPLLSRLGQPPRQSIERASVDALDKSGLRTGGAFVALSGIALAFVLGAYFLFTGSVDQGRGSQDPIKARVEDAKRGLRLLMKGLDEYEEYLDTEKTEDEREESEEPDTSYDIPNILNRIWDNLSSTVNHILDYESHFNNGARTPVSSDYSSGETLFSYSRKPHVMSIFPSSEDSESLGNSGNLIYTNGGKDALSFSFSGSNINNSTEGSTARNNQTIFDIIAQLRQEYLDQREKEKEMKEVNTTTEAYITTADDSSTNEPETNPPTHDTEGQRSALNEERSTGISYEDPDELTTLSTPWESESTEGNGDDEYTVTDNLDSSTLQQEDDQGNVGDDMTTLTFAGRDTTTRTTPTTTPSSLAQKVIINNHLHVYHNPETDPPRSSAFLNNIPFRRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF92</accession>
    <name>A0A423TF92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Caspase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006397</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001811">
        <property type="protein sequence ID" value="ROT75111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF92"/>
    <dbReference type="STRING" id="6689.A0A423TF92"/>
    <dbReference type="OrthoDB" id="6097640at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097169">
        <property type="term" value="C:AIM2 inflammasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072557">
        <property type="term" value="C:IPAF inflammasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072559">
        <property type="term" value="C:NLRP3 inflammasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF3">
        <property type="entry name" value="CASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p20" evidence="4">
        <location>
            <begin position="360"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="608" mass="67069" checksum="2D94E03320575F32" modified="2019-05-08" version="1">MSKESPSTHSPAVQLSSEATASNDISDKDVGKRRNTKATTGEKSGRTSAEARVETPVAKISPIHVSVKRPRTPLSDENLGDPLEKRARIVTDTANEAQMKSRRVNALIRRNIGTKIAANGLFKRIANHSSLQTIKLEAELFKSVENGDSARVQELIQYTGAAVRRSKTSCTLLHAAASHNQADVVVFLLKLISPNITNEEGQTPAHVAAEKGHTQVLKLLVRDPDFDADKRDDLRNSVKTLLGGHLFKAVLEGNKKEAERLLAVGADPDSHGGKLVDGVLARELGVTTPRLLANALNMESIVTLFDKKASKRCSQTVESKSLPSSALSTVHIKVSTRQFRVRRATVIQGGADVYKMDKEARGFVRILNFSCFKDRSDLNLQQLDYDACIMSDVFDKMGYMCKTHSSLTVQQTKEVLKNIRDGDELTDVGCAIFVISGYGVNGRKILTTDMKFVDTDYILNLFKDSECPQLKNKPKLFIFNLFKSEAITSSRSESPKVVRLADLSKDMACIYSNSIGLDCVPNGKGTSFSWSLCRALADHSAEQELGDLYREFLKEYSKSSPSSSPELRLFGFTKSFSLIHCNLNDIPLGILNLVNHCLIFRSITIMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFA4</accession>
    <name>A0A423TFA4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cuticle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001806">
        <property type="protein sequence ID" value="ROT75153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFA4"/>
    <dbReference type="OrthoDB" id="6354620at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="458" mass="50772" checksum="05BEB81F94ED19EE" modified="2019-05-08" version="1">MAQERVRLLGRFLTSVCVERLGTIDLGQGHNWAGSHDVIDHEVYIADASQCPGEGHIRSKDEGSAQLVLPYTAPWVLPQAKLITTPDVKTDIKTIPLVSPYAHPFGHPFVASPYAFHHAAYPYILNADATLKATEFPYIFHKAEQEPAVEEARRRRRDVEIPLPYLHAVPTVTKQTVETKQFEPVDANTPADTTKIELTTKEHEISVPAVKYVQPVVNVKPVTYTALSHAVILVAASCCSAQLVLPYTAPWVLPQAKLITTPHVKTDIKTIPLVSPYAHPFGHPFVASPYAFHHAAYPYILNADATLKATEFPYIFHKAEQEPAVEEARRRRRDVEIPLPYLHAVPTVTKQTVETKQFEPVDANTPADTTKIELTTKEHEISVPAVKYVQPVVNVKPVTYTALSHAVLPYAHGLPYAHGLPYAHGLPYAHGLPYAYGLPYAHYPSLVGAPVIKIDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFC0</accession>
    <name>A0A423TFC0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006319</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001807">
        <property type="protein sequence ID" value="ROT75152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFC0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="48821" checksum="B0BE19BBEE1F5412" modified="2019-05-08" version="1">MIENRLLSPPPPSPPPGLTLVAYTYPPPSIPSSLLPPSFPFLYLFPPVPSHPSISLSLPSYSLPLLFPTIPSIPSISPSYSVHPSISSSLPLSSLPPHPLPFPPSPPSTTPSFPTSLFSPLPSFPSPTPPPFPPLPSISPPSLPTLHTLPPSLPPSSPSPPPPSLPTYFPPSLPPPPPFPSPLHFPPPSLPTLHILPPSSSSLSPLSPPSYLFSPPLFHNPTTLICHLIPANPVCFFAILSLCDWGLFSILFLLLFIFIFFHILCTHSLPHLLVFFHYFFAFYYSPIIFSPFLFPHFLSPFFPTFLFLLLSLSPLSSPPSPSFLPFSILSSSPLHISLLSSQSPLSPFPPLLLPPLLHPLFLSPSSFSSLSSSPPLPFSPLLSSPPPSFSTLSFSLPFLLLFCRTPFPSPLSPSPLLHHSHSLSPLTTNPPPSLPSPLHSPSPTPTPPPSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGX6</accession>
    <name>A0A423TGX6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001745">
        <property type="protein sequence ID" value="ROT75699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGX6"/>
    <dbReference type="OrthoDB" id="6365100at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="293" mass="33660" checksum="5FE313D7AADF4C1C" modified="2019-05-08" version="1">MMGRLKHKDAEIKEKESEINDLHEQMRSDQREMLDQQVKHVRVETENESLKELVKSLEVQLKGEERKKHELEVELKEMEDHLAQIKEQHTQKERSLRRAQRKKEEEALKEKEEMESLKAKLEEREQELRKINLQLGELQLKEPTFNGKSKEGLSEDNWTSGQGESPRAAKFSEANDAISNLQQAGSYEYSQTAGSSKHPQTPFPDKYLQAAESDNDKYLHTSSSDKYPQTEDLNNYPRTEGNGRHLQTPCNTKYPRGAGRGRGRRTSGKRGKFNQAAGRGRGWRAGNGEQATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THR7</accession>
    <name>A0A423THR7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL19m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L19, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005423</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001701">
        <property type="protein sequence ID" value="ROT76034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THR7"/>
    <dbReference type="STRING" id="6689.A0A423THR7"/>
    <dbReference type="OrthoDB" id="432645at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.790:FF:000002">
        <property type="entry name" value="39S ribosomal protein L19, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="294" mass="34371" checksum="152E380D0603EE8B" modified="2019-05-08" version="1">MAGTARQGVLCLARKFAGLELNSRRSAWTAVSKVFPYVSSTDHGGEKKKEVPHDFRVVYPEFIPDPKPEFRNRLREKLERKDMLNRRNIMEIPEFYVGSIMAVTVADFNASGKTNRFVGICIQRGGSGLRAWFILRNVIDHQGVEILYEMYSPLLQSVEVLRLEKRLDEELLYLRDALPEYSTFPLDMDVEPVLEGAPVPVNPIKVQLKPGPWHERWERKDLQGVLDLGLPERFYKRAKLHEKPWEKYDLMKEYRATIPEEEQADIFHEIAPHYPQLEASRRRIRRRRVQSARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI79</accession>
    <name>A0A423TI79_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative mucin-5AC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI79"/>
    <dbReference type="OrthoDB" id="5597713at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="551" mass="58953" checksum="6954B55FA8C50D16" modified="2019-05-08" version="1">MRLYLLRFLLPPAHSHPPIPHHTYPPFLLLAVAGDDEIVQSIQQELQHIGESLDELVLLVNPETTTTDLPSSTVSSDEPASPGSSSTTSASSGASVQSSTTDAPVETTKTQAPVETTETQAPVETTETQAPVETTKTQAPVETTETQAPSFDETKASSSEPSQPSSSEEPQTSTSEPSQSSSSEQPQTSSSAPTTTIPPTPVCITNETSSGNDADLCERLTSVLEDIEAVTSTVAKGTMGQAELDDLRNCSTRLDDVIEDMRNNTDFLASSVDVEELIARKDALDEVRKSEEDGDNVQDFFLLITTTTSPSPFLPTPSLSDHQPNTITATTTSPFLSSSPFPLPRYPSNHDPHYHIPPPLLRYHVLSLLTSAYYLFLSFPSLPPSPPLPSTTTTLPSLLLSLSLPLPSSLLSLSTTTTSPFLSSSPFPLPRPLPSSPPLPFRYHDLSLPLLLSLSIATSHPSLLPLLKVLTEAEKAVEDALSTDDYDPTLAIVLGVLGGLLGVGIIGYVGFTFYKKNKAKKARKNDNPMTSMERGSGQDNSAYAGSSNRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIV2</accession>
    <name>A0A423TIV2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mucin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001667">
        <property type="protein sequence ID" value="ROT76390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIV2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1086" mass="121192" checksum="B693742CCB232A97" modified="2019-05-08" version="1">MPHLTFDKSQITNLLAFTEQILPATHLYCHSVLYQTFPLLFPPRKPFPYPFPSPQTLPLAFSLPANRSLSLFPPRKPFPYPFPPRKPLFPSRKPFPYLFPPANVPLAFSSRKPFLTLFLPQTVPLPFSSPQTLPLPFSLPANRSLSLFPPRKPFPYPFPSPQTVPLAFSLPANRSLTFPPANRSLPFPSPQTVPLAFSSPQIVPLPFSPQNLPLAFSSPQTFPLAFSLFPYLFPPRKPLFPPANRSLTLFPPANRSLSLSLPANRSLTFSLPANRSLSLFPPRKPFPYLFPPRKPFLSLSLPQTVPLPFSLPANRSLTLFPPRKPSLAFSSPQTVPYLPSPQTVPLPFSLPRKPFPYLFPPRKPFLSLFLPANRSLTLFPPRKPFPYPFPSPQTVPLPFSSPQTVSLPFPSRKPFPYPPANRSLTLSLPQTVPYPFFLPANPSLSLFPPANRSLALFPPANRPRKPFPLFFPANHSLSFSSPQTPFPSRKPFLSLFPPANLPLPFPSPQTVPLPFSLPQTPFPSRKPFPYLFPPRKPFPYPFPSRKPVPLAFSLPQTVPLPFPSPANRSLTFSSPQTVPLPFFPPRKPFLSLFPPRKPFPYLFPSRKPFPLPFSLPANRSLLFLPANRSLTLFPPRKPFPYLKPFPYPFPSPQTVPLAFSLPQTVPLKPFPYPFPPRKPFPFSLPQTVPLAFSLPANRSLTFSLPANRSLPFSLPQTPFPSRKTVPLPFPSPNRSLTLFLPQTVPPFPSRKPSLTFSLPQTVPLPFFLPANPFSSPQTVPLPFSLPETVPLAFSSPQTVPPFSLPQTVPLPFPSPQTVPLAFSLPANRSLPFSPRKLPLPFPANRSLPFSLPQTVPLAFSLPQTLPLPFSLPANRSLTFSLPANPFSLPQTVPLLFPPQTVPLPFSLPANRSLFSPPQTVPLPFSLPANRSLTLFPPANRSLSLFPPQNRSLTLFPPANRSLTLFPPRKPFPYPFPSRKPVPLPFSLPAKPFPYLKPFPYPSSPQTVPLPFSPQTPFPSPQTVPLAFSFPANRSLSLFPPRKPFPYPFPSPQTVPLAFSLPANRSLPFSLPANRSLSLFPPRKPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ19</accession>
    <name>A0A423TJ19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001659">
        <property type="protein sequence ID" value="ROT76460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ19"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="105" mass="11366" checksum="3209D0BC2B10218C" modified="2019-05-08" version="1">MATSNGLGLKGKVAIITGATSGIGRGCAVDLARAVRGQVAVVQASGNLPRDGRWTAVHAAGSQMRHCVWVLAGRPIPQTRHNFEADSRWRKVEYQMFSVVSRRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKR2</accession>
    <name>A0A423TKR2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eyes absent homolog</fullName>
            <ecNumber evidence="7">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004321</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the HAD-like hydrolase superfamily. EYA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01001572">
        <property type="protein sequence ID" value="ROT77046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKR2"/>
    <dbReference type="STRING" id="6689.A0A423TKR2"/>
    <dbReference type="OrthoDB" id="167668at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001240">
        <property type="term" value="P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045739">
        <property type="term" value="P:positive regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028472">
        <property type="entry name" value="EYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038102">
        <property type="entry name" value="EYA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10190:SF16">
        <property type="entry name" value="DEVELOPMENTAL PROTEIN EYES ABSENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10190">
        <property type="entry name" value="EYES ABSENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR628472-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25595" checksum="132421B7A1C3A191" modified="2019-05-08" version="1">MRAVQSGSRRRPRAAGPSQALMAAFFLCPLPHQCSELRQGFLPRSFESTPPSITAWTCVPHCLPHTSISHSVCPLMLTGLMRLGAEIRTSLLDPENREKWHRVRQEIETLTDQWLTESMKCLQLIASRPNCVNVLVTTTQLVPALAKVLLYGLGSVFPIENIYSATKVGKESCFERIASRFGRKPVYVVVGDGRDEETAAKQLDFPFWRIQTHHDFVNLYKALSVCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMQ1</accession>
    <name>A0A423TMQ1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003558</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001483">
        <property type="protein sequence ID" value="ROT77751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMQ1"/>
    <dbReference type="STRING" id="6689.A0A423TMQ1"/>
    <dbReference type="OrthoDB" id="6360807at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="57"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="561" mass="59068" checksum="C628CDBEC8837F11" modified="2019-05-08" version="1">MAVLSPPHRLRQLEDGVVEWSSALSVKGVARGDYGNYSCVATNALGSHTASLVLVPPPTPATPTNLTVSRASSVVIRFRLLSAYWHRVNEEANLEDVDGGGTNSTTVSGLSAGLEYFFSVQAYNAQGRSQHSAPPTPVTLLGAVESASSPSTGEGGGPRVIRVPRLLLLIMTLAGTALLALNMAIIACFVRRRAVHGNRGVSASSSKNTTLEVFSTATSPTSPQGDGLPLTTTGSTEDSQKGALKGECQTDVDSCDQTKLLTYHPTGPAAPRVMGPLLADASRLERPARTSGQVLPVNGSVYGCSPVAQSDLVLSERSVAPGAANHPDVCPTSTATTAQYTHQHSNHLQQHPQQHQYIQLQQLPRHQYHQQLPQPQAPPNLIQNHKQQQLQHPNFAHHPSHTYQLADPAGASSQPEARAPAPATSTYATLNPRDLARSGDLMAGSGSVCSYATVAPRRQRPPTSRPSTLQRNATICTSEMEPGVAVAVGVAEGSAAGSQKEHQTSAEADRAPAASTTSRGLVRRASLFADFSWQSPLQPHCPLDPASSTRDPDGSADASNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPZ0</accession>
    <name>A0A423TPZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative WSC domain-containing protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WSCD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001368">
        <property type="protein sequence ID" value="ROT78528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPZ0"/>
    <dbReference type="STRING" id="6689.A0A423TPZ0"/>
    <dbReference type="OrthoDB" id="6351622at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF9">
        <property type="entry name" value="SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="114" mass="13207" checksum="FCDEF94EF7AB719B" modified="2019-05-08" version="1">MPERSYSYKLWFGLRVPSTWLLSFPRSGNTWTRYLLEAATGVVTGSVYHSKYLKGLGYMGEDDPLWWRTSLVIKTHSLLPLRIHPDYPVIAIIRNPARYLYQEGYTSSVDSPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSU8</accession>
    <name>A0A423TSU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein SMG9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001232">
        <property type="protein sequence ID" value="ROT79529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSU8"/>
    <dbReference type="STRING" id="6689.A0A423TSU8"/>
    <dbReference type="OrthoDB" id="79514at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039177">
        <property type="entry name" value="SMG9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14270:SF0">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="519" mass="57824" checksum="E3384A8EDAE349D1" modified="2019-05-08" version="1">MADVGDKATRNKKKIRKVYQKPDREFETFLPDSMRAPAIQVLGKPPHEYKGGSSTYPNHYEHPHPHNWEKRGGGRYHDDWDKRGSYGSGMLKISEGGRNTIFTRDAGRPPGRGQEADRGDPDGSQNVTTPTPVILSRARSNSENRSTSPNPSVTAVRKDSVPSVVTGGSSSSQQYQIASKPLMEASLTPERMMKGPARLLDETLNLCDDLASYLLDQSNFMVVALMGTQGVGKSVLASLFVDPETDINKMRSCTFRPESLEQLMSGCHGTNGIDIYITSHRLFILDCQPLLSPSIMDRIVTQEKKFTSDYNSTENLMEVESLQLLTLVMSIAHVVVLVQDSGTDPNLIRLLQTCEMMKPSSSSTPSSSSSSPSAPSGGDETQQYFPHVVFVHNRAPSHHFSPSTLKKLQGVYQEAFMGSCLENESRIGACNGLTYAPLAQTSCGSLVNLFLLPDLRSQPQSHVRFSEALREMRRQVLSLRRLPLTHLTLTEKSWYQYVCRTWESVRKWSLFVEYSRLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVE1</accession>
    <name>A0A423TVE1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_000821</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TVE1"/>
    <dbReference type="OrthoDB" id="408532at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000027">
        <property type="entry name" value="Beta-glucuronidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="12">
        <location>
            <begin position="253"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="13">
        <location>
            <begin position="840"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1128"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1130"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT80426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1684" mass="191316" checksum="F3BABC857E41BD4E" modified="2019-05-08" version="1">MTCSSDVAFNSVADKEDTVVIVSTGVYTLPAGKASIILGSLKQKDERLKNGTSILISGLPLGENCIVIPVVAKAEDVVKVLVCNFGRTPFLVHSKRTIANAVSIQDDEEEQLGRLPTDHWEKQRVLTRMSINAVVTEVKPDDVEEEDPLDQALQIDPCCVVKNGPVYDEKRFQKLLKALDADRWILKEDQRKAAESMIWEFQEAFNLKEEPLGRTNLVEHKIETGDSDRVYVPPRFIPYALRPAVEAEVQALKEQGHIRVSSSEWNAPIVLVKRKDKSHPRLCVDYRALNSQTKLEFYPLPLIEDILYQVSQSKWFSTLDLRSGYHQVPLDDDSIPKSAFTTHEGHFEYTVMPFGLSNAPRTFQRLMNRVFSGQIGQGLQLFLDDIAIYTDDIDRHLQVLKEALGRLIKAGLKASPEKTRLFQQEINLLGHRVGHGEVKAALDKLAAVKDFPTPKNRREVRRFLGLTGYYRRFIEKYAQKAQPLTKLTSEKQPFIWGSEQEEAFEVLKRSLLKEPVLRSPDFSRTWYISTDASKGAIGAILAQRYDGHFCPVSYFSRQLRGAELRYDVMEKEALAVIEALKKFKPLIWGLEVIVMSDNRSLQWLFHKAKDGNARVTRWALTAQSFGAKILYHPGKLNAAADALSRIEAPEGVDPEDIEKASTMIIDEAQNCRILMAVVANNLGGKTRQDEQEDDEEDGHPWSIDEMIREQNQDPLYSPVIKYLQTKNLLDKRKVDPNLVVEDYFLDQGLLYKQVRTPNSARDIKEVLCVPRTLVPKALALVHLAPLGGHGAEERTKFRARQNFTWRGMDRDIAEYCRKCITCAKFKGRAHPLTPLRRYPVPLEPFQMVSMDLMGPFPLTERGNQYILVIVDFLTRFAVVRALPNKYAETVAEAVSEVFADLGIPQTVLTDQGREFRNEILKEMAKHMQFQHHKITAYHPASNGLCERTNQQVLNILRGMVDGKDQYWDLYLKDTQMALNSAYHKAIGDTPYYAMYNRDLKTSDLWWTRPTSFGGPPDEDFITARTQRSKEVYEYVRDNLLRAADEQCRIRQKKSKDTTVLPGMRVFIKAVKKKGDSKLSPRWEGPFRVVEQIRPYVYRIKHLQTEKMKEVHLENMKIALEASIPRSLAPEARRPYPQETHSDIRPEGTSEEEEAREEEYVMNFPTNDDGKGTSESNQDWAQESTALLTGTLAEDSKWGGLYPRESGSREVKSLDGLWNFRLAPLHDPLQGFREEWFLRPLSKTGSVISMAVPSSYNDVTQDKALRDHIGWAWYDRTFYVPVRWQTDKQRVVLRLGSAHYNSIIYINGVAVTSHEGGHLPIMAEISSGLRFGKENLVTVAINNTLTPSTLPQGKIVYHNDPTKYPPGYFEQTLDFDFFNYAGLHRPVYLYTTPQTYIDDIVVNTDIDGSAGIINYKIFAATSGIGPQTEDNVGCSVKLLDNEGDHVTSAMGCAAVSDEHGVLDLYPQKIRGKGVDYPLIVKDFSLLKWLGANSFRTSHYPYAEEIMDMADQEGIMIVDESPAIGLNGFGEELMKRHIASCRNFRRDKNRPSVIMWSVGNEPKSYEPAAKEYFSAVVNATKEADPTRSVTCVLSVDKHTDLAGSSLDVILVNRYFSWYSDTGHLELIYNQTVNEFMEWHLLHNKPVMISEYGAGSIAGFHMVTIEPLNTGLCDTHLFPCLWTFFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWB7</accession>
    <name>A0A423TWB7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001076">
        <property type="protein sequence ID" value="ROT80736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWB7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="537" mass="60429" checksum="27CBF8C0711D55EB" modified="2019-05-08" version="1">MASFQLERTTEGVVEEENGPTVQRRRLLEPYSSCFVLFFFSFLIFFSLHSTYFFLLILSHFPPFYPSSPSLTLYRFSVPSPFLPPTFLSVFLPFPIPSSFFSFLFLLLFFLFRLSPSSPLPLSFPSSSLFFSFLPLLYPFFLPLLSPPSFFPFPPPLHSLPSFSPSSSSLLSFPSFSSSSPSLLHSFQSIFPSSLPLHSIPSFSPSPLPPFFFSPLFSPLFPPLFPSFSPTLSPLHSFPSFFPPLHSLILFSAFLPFLSTPPPFPSFSPSLLFSVFLPSSHPSPPSFLSSPPLPPLFFFTVFSLSLPPPFFVLLPFLSPLFLFSVFLSSPPHPFFLLLPFLSPSFFFPSFPSLLSPPFFPSFSLPLPLFFFSVFSFPSSPPPFFSVLLPFLSTLFLFFRLSPFPLYPFFPSFSPSPPLSFFRRSPFPLPPFSVFLSFPLPLFLFFRPSPLPLPPLLFSVFLPLSPPPLFFPSFSPFLSPLFFFRPSPLPLPPLAFFPSFSYNATYFSHDLPRLAHPQCPLSPRPHCQRAGAVGTGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXV7</accession>
    <name>A0A423TXV7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative G-protein coupled receptor moody-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_000017</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001001">
        <property type="protein sequence ID" value="ROT81232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXV7"/>
    <dbReference type="OrthoDB" id="6117944at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24228">
        <property type="entry name" value="B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24228:SF74">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="98"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="395"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT81232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="50633" checksum="94D64F5A4866E622" modified="2019-05-08" version="1">MKSQREADSCRNSTDFRGRVSRRRWRRFPLRRGEDPPACGERTAGYSEEADSATPTPVVAKLRISAMDQSAEPAPAQRWAMMLTAVFAVVIMFIGFFGNLLTVLALPYSRRHRKTTTWFVVNLAAAAGVVRVTILPVTAAHLISLYMTAHALLSDSACAYFAFCRYVTMLVGLLSIAAIAINRCVLITMPKNYPKIFTSTNTSVTILCIWLLSIVLLLFPLLEAYGKFGYNDSTDECDFVDNTALGQSPRNVMMFAGYFLPCGVIVVSYALIFYKARMSSIKMKAITQANSQSAANTTAQRPAVGLRSRDIRIARTIAVIFVAFLVCCTPVSVLHYLDKQIHMPTTLLLLHPLYWLQYCLNMFIYVIMNSQYREAYVHFVAKWWPGVRNISGRLFREPSSDSGRSQRATTPTSLLRFSTRRGPGKPHTSTQRQPPPDIFETDTRTPSLDPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2Y0</accession>
    <name>A0A423U2Y0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023747</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="QCYY01000742">
        <property type="protein sequence ID" value="ROT83080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2Y0"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000004">
        <property type="entry name" value="Glycoprotein 3-alpha-L-fucosyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="15">
        <location>
            <begin position="325"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="14">
        <location>
            <begin position="454"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="647" mass="74010" checksum="D1A6CD045E887028" modified="2019-05-08" version="1" fragment="single">MHLPLPPPLHLSLSPPLPISRLPLLSTPLSCFSPCPHRRQLVGSRDRGPSMMWGGVVLAKDLLGSELLTDFLDRYWQNTQAGPVWNPEEVSGDMAGGNLGPRAMFGEVEGLLRGTHVDIHAQVQEALYVDLAERQPYDGNGLSEDGCLHQHNIGGDYNTNIGYLDHTLNNPYNGAYGKELLRYTSNLMSWYTGTELDFQDATIEGLFAAYLECQQWLFRGHTQEPTTCGRHMTDALPNASPRSHTVERGRSDVVASPFKLLGQRSSEVTEISFRESYTPVQAVHVLARTEERETSENETEPESTDASEEHATDTEELVPTERPLKKILFWNDAYLDKHFGFGEGRDIFKEAGCKVDACFATSNRRMFPLMEVDAVLWHSRSGDLSLPRIRSPHTRYVLWVRESASYPGYIADFRHVFNWSYTYRLDSDFLNSYGTVIRREDPHAYPTYRNHATGKRKLVAWFVSNCRPPSGRDLVAKKLQDWIQVDVYGKCGPLKCRQNALCMQMLEKRYKFYLSFENSLCLDYATEKFFKILKLDIVPIVYGLANYSAIAPPHSFIDALAFRSAQDLAHYILYLDKNDTAYNEYFRWKPHYDLQDRQIHTANVFCDMCERLHSDNTTKTFDALEWFVHDSKCVTRDSERVQSFING</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7S2</accession>
    <name>A0A423U7S2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_022050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000502">
        <property type="protein sequence ID" value="ROT84763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7S2"/>
    <dbReference type="STRING" id="6689.A0A423U7S2"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF677">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="7">
        <location>
            <begin position="558"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT84763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="75206" checksum="975204B69BED5E7E" modified="2019-05-08" version="1">MGVGRPGAGITSPVKIVANIFISFIGAGMLGLPFAFKEAGIMEGALIMAVVGYLSVAAMLMLIDCKYAILSSGGRAGGRSIIMEKKVPLLPPDSSDDEDEDERHPPTPSTDLTYGDVGLYALGPGGKRLVDIAIVVSQIGFCCGYLIYLCKNLNLYIPRISQKVWLILLLPPLYLLTLLRHLNKLAVFSLFAQISNVLALAVVFWFDFSHSEEVPFQPNEFSIKGFPFFFAVAIYCYEGAGMIFSLEESVAEKKRDKFRSIFVCTMTGLTTLYICFGVSGYASFGPHTMDIITLNLPHSSGSVDFAAMVKICLGISLFFTYPMMMFPVTHLLDKTFGLQNAPHKGNMLRMVLVGLTGLVVSAVPNFGILISLIGATCCTLLAFILPAAFHLSIFRQRLTKRQWYFDMFLVVLGIIGSVVGLWDAFNRMSEGHDPLLEVNEFSQSTGRNNSLHSHVKIAEKQTVDVAQFTAATAQLSNNFSSLPPSLRAAAVKIEHISIMRLSLSLLWAAAAVCSAESRRSGSANAQCLGKLVVDLLTEIRDGFGCHAGTRCPPSFHDADGTCLYLDKTRYSSWIAARQVCFNMGADLAVFADANAFASALRYINGVVDRDADEVPYIYVGGSDEDEEGAWRWHTGQLMPGGAPFWGSSLTPGFSSQPDGGRLQNCAALNKMDSYYLHDGECDLLASALCQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB98</accession>
    <name>A0A423UB98_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000109">
        <property type="protein sequence ID" value="ROT85988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB98"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="148" mass="16474" checksum="F32A69184B44099F" modified="2019-05-08" version="1">MLHISRILSSFSRYERSMEANGDLGSPLLRRKVMCHTDTADDLVDYRVPLAIKALTQTPASFSPPPSPPIPALFTPRAKRIAREGSPPFSFHSRSPKQRTRNRASLHVGERVRITSAANVGFLSRFGPEQHSRSLALRIVSRDSQARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQ73</accession>
    <name>A0A3R7LQ73_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020737</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004141">
        <property type="protein sequence ID" value="ROT61485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7LQ73"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048407">
        <property type="entry name" value="Dumpy_DPY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003645">
        <property type="entry name" value="Fol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963:SF39">
        <property type="entry name" value="DUMPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22963">
        <property type="entry name" value="ENDOGLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21164">
        <property type="entry name" value="Dumpy_DPY"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="43"/>
    </dbReference>
    <dbReference type="SMART" id="SM00274">
        <property type="entry name" value="FOLN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00286">
        <property type="entry name" value="PTI"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="18"/>
    </dbReference>
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        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="26"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="33"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="92"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="196"/>
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        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="256"/>
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        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="311"/>
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        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="417"/>
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    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="690"/>
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        </location>
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="737"/>
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    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="861"/>
            <end position="900"/>
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    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="921"/>
            <end position="958"/>
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="1033"/>
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="1080"/>
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    <feature type="domain" description="EGF-like" evidence="7">
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    <feature type="domain" description="EGF-like" evidence="7">
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    <feature type="domain" description="EGF-like" evidence="7">
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="1352"/>
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="1395"/>
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    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="1832"/>
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    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
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            <begin position="2947"/>
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    </feature>
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    </feature>
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    </feature>
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    </feature>
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    </feature>
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            <begin position="95"/>
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    </feature>
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            <begin position="259"/>
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    </feature>
    <feature type="disulfide bond" evidence="5">
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    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="924"/>
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        </location>
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        <location>
            <begin position="1355"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="4078" mass="429935" checksum="6D9B5F6FA7D0C2D2" modified="2019-04-10" version="1">MNARNPCECRLDGRQHVLTLCSALLAVPKPEPPRNPCSGDPCGPNAACREINLQRVCTCLPGFVGNPPACRPECVVHPECPPLLACLNNRCVDPCKGTCGINAECRVINHNPICSCLGGFTGDPFVRCTPSPIAQPTPPPVVRPPITPDTPRPTSPMPPIAGTPPPIKDQTIVPSAVDPQGTPPPIVDLPEPPAPPKDPCVPDPCGSNSYCRQNGDRYVCECREGYFGNPEIGCGPECVLSTDCASRLTCVRQKCVDPCPTACGNGAQCTVVNHRAVCSCPQGLQGDPYTQCVVSPIVGTTPSPTPMQPTAKTPCEPNPCGQNAECKPVGLDERCSCLPGFFGNPYDYCRPECTSDPECPSYLACVNQKCIDPCPGTCGINAECLVVTHAPMCYCRPGYVGDPYQSCRPEPVTTPSPLDPCNPSPCGPNSECRTVGDRPVCECLSGYFGSPPDCRPECIVNSNCPVIMACVNKKCRDPCAGACGTDALCEVVNHNPVCYCRQDMTGDPFIRCIESTSPKPHEPADPCASNPCGLNADCSFVGGLVVCKCQGDMIGNPYEACRHPCTVNSDCPSNKACSRNKCVDPCIGACGINAECHVSRHRPVCTCPHDLTGDPFSRCVLVTPTTSVPDDPCSPPPCGLNAECKRRGTASYDCKCIRDYFGDPYTECRPECVVNTDCPSDMACRNLKCIDPCPGTCGINAQCNTVNHKPGCACLPGFEGNANDRCQVQAVTPSAPTSDPCALDPCGPYSSCRVVRNRPVCECLPGYYGAPPNCHPECTTNPDCPKYLACVNEACVDPCVGTCGVSADCQVVNHNPTCTCPRGYVGDPYIQCRLVELTSKSPVPTSPTTISTPTVPTIATPARPCASEPCGLKALCKPLGEYFECTCPPGMFGNPYVECRYECVVDSDCARNRACERNKCIDPCEGVCGERAECHVIMHRPVCTCVPGFTGDAYTACNPVKVTTGLPPSLPQREEPCQQTTCGTLAECHEEDGRPVCHCIEGFVGDPYVACRPHCSADSHCASGLACVNDKCIDPCPGTCGINAECRVPNHVPICTCPPGYTGSAYQRCFPKPDTSSESGEDLCEVCGSNAECRIVDGRPVCTCLPGFLGAPPNCHPECIVNRDCSTTEACNKQKCVDPCIGACGTNADCRVINHSPVCTCLPGYTGEPFVRCNRIPVAQPTLAPPVTERPDPCREGTCGPNANCRVQGTRGICTCIEGYFGNPYVQCRPECVINSQCPQYLACNNQRCVDPCPGTCGIDAICEVVNHNPLCSCPRSMTGDPFVRCEPIRAPPDPCIPTPCGPYTKCQVVKDRAVCSCLPGYFGNPDLGCKTECTINSDCPLSSACINRKCVDPCIGVCGNQAKCSVVGHNPLCSCPDGFIGDPLTSCRLKPDVPVDPCNPNPCGINANCEVKNNRAFCTCFPGYFGNPDVECRPECIINSDCPRYLACANQKCIDPCPDSCGINALCDVINHNAMCSCPRGYNGDPYVECRVAPPPPVKCSPNACGFNTECRVTNGIPICYCLPSYTGDPYKERVSTSAASIPALPASLVLWGQSVLSSAIALCADVLQASREIRRFPALPSRLPPNQTVLLTVTAHWTKHAQGGNVTTLHAVESITDLCASVFQDLLPPIVEIQTLPTSVTRPPIAVTTITHSPIAEYPTTEHPRPKTPSPRPPFLPPLPSISVGCKSNDDCPYSNSCINKLCVDVCHQGYCGKNADCSIKFDIPMCSCPPGTSGDPFIRCKAVATEAPPTTLAPLADTHSPLQEAPLNPVVGSTSPMPPPLAAASTTRIPDTAFIQPTTIHSLPPPITIGCESNDECPYDNTCINKLCGDVCSPSLCGEDAECHTLSNRPSCFCPPGTTGNPTIKCTAILTERPSTLHPPIAETLPPPPAVPVQPISSPSHTPHPPIADVGTPRPLPLPFDEPEKPLPPIIPPIAIACENNDDCTIDNTCYNRLCYDVCVLGICGEEATCTITIHRPVCTCPPGTTGNPTDRCIALLTEKPTTFSPIAETNPPTKDEPIIPEALPGSTTMIPLVDPIHKRPTTPIPLPPEPPTPSPIVVGCESTDACPSDNSCINKLCLDVCFPGFCGENAECQTVQHRPKCKCPPGTSGNPTIKCSAIAVDVLPLPIAEPKPAPPHEQVIPIAGPTTTGLPPLAEHVTRPRPDITVTQPVPPPVGCKATTTERVTTHSPMTDRPPQQPVVPIQPIAGPSSELPIPVAEEPTTRPPELPLTTHRPVPTPPMIPIGCTTGNPTDHCVALGTDRPTTVIPLAERPIPPSDANIIPGIGPSSTPLPPLAETSIRPTEPPLPSTTPSPIVPPIVIAWTTGDPTRGCYAELTERPLSPPSPIPETRPPQDEAPIRPIAESSSPGLPPLAELPTPRPKPPPVTTPPPPPTPGTTGNPTIKCSAMVVDTPSTPYPPIAGEQPVQPDSPISPISGSSTTGQPPLAEDTIRTTPAPLPVRPTPQPIVPPISIACTTGNPTDHCVALGTDRPTTVIPLAERPIPPSDANIIPGIGPSSTPLPPLAETSIRPTEPPLPSTTPSPIVPPIVIACENNDDCTTDNSCINNLCYDVCSLGICGDDADCRIRDHRPVCSCPPGTTGDPTRGCYAELTERPLSPPSPIPETRPPQDEAPNKTHCRIIKPGLPPLAELPTPRPKPPPVTTPPPPPTPGPIPVGCETTDDCPSDNSCVNRLCLDVCYPGICGNNAECQTHGHRPLCTCPPGTTGNPTIKCSAMVVDTPSTPYPPIAGEQPVQPDSPISPISGSSTTGQPPLAEDTIRTTPAPLPVRPTPQPIVPPISIACENNDDCDIGDSCINMLCYDACSLNFCGEDADCKTIDHRPVCVCPPGTRGDPQIGFVATVTEKVTTIPPVTDRPPQQPVVPIQPIAGPSSELPIPVAEEPTTRPPELPLTTYRPVPTPPMIPIGCESTDDCPFDNSCVNRLCMDVCHPGLCGENADCQTVGHKPSCLCPPGTTGNPTDHCVALGTDRPTTVIPLAERPIPPSDANIIPGIGPSSTPLPPLAETSIRPTEPPLPSTTPSPIVPPIVIACENNDDCTTDNSCINNLCYDVCSLGICGDDADCRIRDHRPVCSCPPGTTGDPTRGCYAELTERPLSPPSPIPETRPPQDEAPIRPIAESSSTGLPPLAELLTPRPKPPPVTTPPPPPTPGPIPVGCETTDDCPSDNSCVNRLCLDVCYPGICGNNAECQTHGHRPLCTCPPGTTGNPTIKCSAMVVDTPSTPYPPIAGEQPVQPDSPISPISGSSTTGQPPLAEDTIRTTPAPLPVRPTPQPIVPPISIACENNDDCDIGDSCINMLCYDACSLNFCGEDADCKTIDHRPVCVCPPGTRGDPQIGCVATVTEKVTTIPPVTDRPPQQPVVPIQPIAGPSSELPIPVAEEPTTRPPELPLTTYRPVPTPPMIPIGCESTDDCPFDNSCVNRLCMDVCHPGLCGENADCQTVGHKPSCVCPPGTTGNPTKHCLALVTDRPTTVIPLGERPQPPADVNIIPGIGPSSTPLPPLAETSIRPTEPPLPSTTPSPIVPPIVIACENNDDCTTDNSCINNLCYDVCSLGICGDDADCRIHDHRPVCSCPPGTTGDPTRGCYAELTERPLSPPSPIPETRPPQDEAPIRPIAESSSPGLPPLAELPTPRPKPLPVTTPPPPPTPGPIPVGCETTDECPSDNSCINRLCLNVCYPGICGSNAECQTHGHRPLCTCPPGTTGNPTIKCSAVAFDIPTTPYPPVAGEQPVQPDSPISPISGSSTTGQPPLAEDTIRTTPAPLPVRPIPQPVIPPISIACENNDDCDIGDSCINMLCYDACSLNFCGEDADCKTIDHRPVCVCPPGTSGNPQIGCVGTVTEKVTTIPPVTDRPPQQPVVPIQPIAGPSSELPIPVAEEPTTRPPELPLTTYRPVPTPPMIPIGCESTDDCPFDNSCVNRLCMDVCHPGLCGENADCQTVGHKPSCVCPPGTTGNPTDHCVALVTDRPTTVIPLAERPLPPSDANIIPGIGPSSTPLPPLAETSIRPIEPPLPSTTPSPIVPPIEPQEIQLEDVMLCSLKGLHLLSLLYQRFDHQRMRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSH7</accession>
    <name>A0A3R7LSH7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003988">
        <property type="protein sequence ID" value="ROT61795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSH7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="640" mass="66450" checksum="37DA7FD0C29D1D51" modified="2019-04-10" version="1">MNHSRKRLLGEERKSGPVLPSRGMEPLMPSLSNAMGGMPLGVVAQAELSPLFLHLPPIPSPPPPSLPLYLHTSSSFTPTPPPFLHTQPPPPLLPSLPPPPSSFTHTTLFPFPSSLPPPLLFLLRLFGLFRLKLQSFLTEGSAGHVLLPPPLLRRPPFSPPSSPPSQPSFHPSFHPSFPALLSSPPFQPSFPFQPSFPLLPASSQPSFPALLPALLSTLQPSFPALFPALLQPSFPSPPSQPSFQPSSSPPSQPPPALLPPSFPPSFPALLSSPPSQPSFQPSFPALLPSSSSSLLPPSPALLSSLLSRPSFPASHSSPPFPPSQPSFPFSPPLQPSSSLLSSPPSQPSSPALLPHPSPPSQPSSTTAPFLPGLLLPALLPSLPSPSPGLSSQPSFPAPSQPSSPALFLPSFPALPPFQPSFPALPSSFQPSFPSPSFPALLSSPPSPPSFPALLQPSFPALLPSPPVPSPPSQPSSSFPPSQPLLPSPPSQPSSPAPPLQLLPALLPSPPSQPSSRPPSPASPALLSHPSPPPAPALLSSPPSPPPLLPSLLLPSLPPFQPSSPPSSPPPASLQSSFSHPHPALPSQPSPLLPNPPFHLPPRHSSSPSSYRVPAALNKSSGSSFTSCDTSALLTIIITSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSU5</accession>
    <name>A0A3R7LSU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 70 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003863">
        <property type="protein sequence ID" value="ROT62019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSU5"/>
    <dbReference type="STRING" id="6689.A0A3R7LSU5"/>
    <dbReference type="OrthoDB" id="6351471at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000134">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="580"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="582"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="603" mass="66292" checksum="08153FFFA56969C9" modified="2019-04-10" version="1">MAAPAIGIDLGTTYSCVGVFEHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRKFEDATVQSDMKHWPFAVINEGGKPKLRVEFKGESKSFNPEEISSMVLTKMKETAEAYMGKAVKDAVITVPAYFNDSQRQATKDAGTIAGINVLRIINEPTAAAIAYGLDKKSVGQGERNVLIFDLGGGTFDVSILSIDDGVFEVKATAGDTHLGGEDFDNRMVNHFTQEFQRKFKKDLSSNKRSLRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKALRDAKLDKTSIHESYEAVAYGAAVQAAILRGDQSDTVKDMLLLDVTPLSMGLETAGGVMTVLIKRNTTIPTKHSQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFDLSGIPPAPRGVPQIEVTFDVDANGILNVTAVDKSTGKENKITISNDKGRLSKEEIERMVNEAQSYREEDAKQRDRIEAKNRLESLCFSIKSSVNEAGVCGKVSPDEKRCVEGKAEETLRWLDANQLAEKEEYEYKMKEMEEVWRPIASKLHGSGGCPGYGASTGNGPTVEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTB6</accession>
    <name>A0A3R7LTB6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Actin-related protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_018248</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP8 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003365">
        <property type="protein sequence ID" value="ROT63840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTB6"/>
    <dbReference type="STRING" id="6689.A0A3R7LTB6"/>
    <dbReference type="OrthoDB" id="5572108at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10206">
        <property type="entry name" value="ASKHA_NBD_Arp8-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000121">
        <property type="entry name" value="Actin-related protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="375"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="391"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT63840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="62897" checksum="C5F6E614BD728DCC" modified="2019-04-10" version="1">MDGVHGVAGHGHHLEAQASIIIHPGSRYLRLGRPSDSVPHTVLHAIARKRKKGLPVYSDPFVIPQAKLDREAVQELEECRLKVSHILQSSLMSDGSRRFATPPQQIAAYNKRLQPAQEETAEPSPPWVHSDKDFIVGDEILSLHPSEEYNIHFPFVRGDLNIHKSLGGSISAVLADLETIWGHCISNVLNVPIKDLKFYRAVLLIPDIYNRDYVKKLTNLLLNGLGFGGCFVLQDHVAATFGAGLGYACVVDVGDQKTSVSCVEDAISHPATRLRIDYGGADVTQVFHWLLKKSGFPHQVNPANKLDAMLLSKLKHEFCHVNLNVCGAQEKKFTVHTPGKMPISYTIQMGDELIVAALSLFYADLLKITGPKMMHTQKPNMGDPDDPFDENYLRETSRRGGREAAEAMDVGGGDAGDGGEEDIVVDDQPLPPSQIPSSSSARNDSLAFNSNEKLLSLEQAILTSIDRCQSDEMKRKMYSSILMVGGGAKFESLGKWLQSRLLLQIPVAYRPEQIEIITRAKDMDPCMTAWKGAALMTCLEGSNELWIQQAEWNKHGVKILREKCPFIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LY33</accession>
    <name>A0A3R7LY33_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rab-like protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002965">
        <property type="protein sequence ID" value="ROT66268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LY33"/>
    <dbReference type="STRING" id="6689.A0A3R7LY33"/>
    <dbReference type="OrthoDB" id="48625at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001656">
        <property type="entry name" value="Rab11B GTPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="24065" checksum="5FA066FBD85E8571" modified="2019-04-10" version="1">MSEEVNQEKDACGEDTKLDYDQKTKKGELAVKVICLGDSAVGKSKLVERFLMDGYQHQQLSTFALTLYRYRTKLENKDVLVDFWDTAGQERFQTMHASYYHQAHAAILVFDGTRKVTYKNLANWYKELRHYRPEIPCFCAVNKIDENEDIAGKSFAFPEKNNIPMYYVSASNGTNVVKLFKDAISAAYQYKKNPTDFTDQIMEELEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZC7</accession>
    <name>A0A3R7LZC7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CXXC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_019056</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003498">
        <property type="protein sequence ID" value="ROT63071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZC7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008327">
        <property type="term" value="F:methyl-CpG binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040388">
        <property type="entry name" value="CXXC4/CXXC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002857">
        <property type="entry name" value="Znf_CXXC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13419:SF0">
        <property type="entry name" value="CXXC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13419">
        <property type="entry name" value="ZINC FINGER-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02008">
        <property type="entry name" value="zf-CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51058">
        <property type="entry name" value="ZF_CXXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="CXXC-type" evidence="10">
        <location>
            <begin position="366"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="276"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT63071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="47828" checksum="87CB956E95078F20" modified="2019-04-10" version="1">MVLQPDSRVDLVSLCLPLYPLLSIFCVSFLPLLYHPSLSSRSPSSPSPLKMPNYLYQVAMPPHFAPARRGRRRPLVSCSVRVGMSSVPGPYNCLPETMELGEGLTGRLLDTHNLLFGDGYSDTLSSRIVGADGNSAYRPWEADHPADHRQPDHRLHPLAVSSAPIQVLTHTPAVPTASNQMSHYGHTMPTYSDSFGAGPPAHHVPPQHPVPHKLPPFAAFSPDRSVGSTTPSPLPSFNTLPSPHSRYPLVPAPVQAREIPTIQQQMMDERHIRMFESPQGSDPAPSSTTPAQASPNTQPPTGSGVRPRGREAGGSRGVPRELGKRRVRLGHGEQRPGVQRVLHRRQQLRCLQHPRRHGCLRLQKPVKKKRKRCGDCVGCQRKDNCGDCAPCRNDKSHQICKMRRCDKLTEKRSAQYGPSDYGSLPLFTTTQADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZJ4</accession>
    <name>A0A3R7LZJ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="3">4.1.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DNA photolyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Photoreactivating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_018906</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).</text>
            <dbReference type="EC" id="4.1.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003473">
        <property type="protein sequence ID" value="ROT63214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZJ4"/>
    <dbReference type="STRING" id="6689.A0A3R7LZJ4"/>
    <dbReference type="OrthoDB" id="496749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009650">
        <property type="term" value="P:UV protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000002">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.80:FF:000004">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000110">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032673">
        <property type="entry name" value="DNA_photolyase_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052219">
        <property type="entry name" value="Photolyase_Class-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211:SF0">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTO-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01084">
        <property type="entry name" value="DNA_PHOTOLYASES_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="15">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00083107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT63214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="47576" checksum="6454496681F4660F" modified="2019-04-10" version="1">MSRDQRVQDNWALLFAQRLALKNKVSLHVVFCLVPKFLDATIRHFHFMLRGLEEVEKECKDLNIEFHLLLGEAKDVLPTFIKEHKIGGLVTDFSPLRVPRQWLKDVKKAIPSNIPMCKVDAHNIVPCWITSDKQEYSARTIRKKIHDKLPKFLTKFPPVAKHRYTSKYKSKGVDWVEAEKSLEVDQTVKPVDWATPGTRAGLDLLNEFCLKRLRKFAESRNDPTINALSNLSPWLHFGQISAQRCVLEVKRYNKQLSKSVEAYVEEAVVRRELNDKRPYIYTRETLEEGKTHDELWNSAQIQLVTEGKMHGFLRMYWAKKILEWMKSPDDSLATAIYLNDKYSLDGRDPNGYVGCMWSICGIHDQGWGERQVFGKIRYMNYDGCKRKFKINAYVARYGGKQHRYIPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZM8</accession>
    <name>A0A3R7LZM8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell surface glycoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002622">
        <property type="protein sequence ID" value="ROT68908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZM8"/>
    <dbReference type="STRING" id="6689.A0A3R7LZM8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="578"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1233" mass="126893" checksum="16C22F7AD5223AB3" modified="2019-04-10" version="1">MLSGLPFLSSPAASVAVRASFPLLSCCLCCCQGFLSSPLLLPLLLSGLPVLSSLVASVAVTASFPLLSCCLCCCQGFLSSPLLLPLLLLRLPFLSSPLASVAVRLPFSLLLPLLLSGLPFLSSPAACVAVRASFPLLSCCCQGFLSSPLLFVRASFPLSSCCCQGFLSSPLLLPLLLSGLPFLSSPVASVAVRLPSSPPVASVAVRLPFSPLLLPLLLSGLPFLSLLLPLLLSGLPFLSSLFLCCSIAPFLSFPVASVCCRCSLSSPLLLPLLLSGLPFLSSPVASVAAVALSSPLLLPLLLSGLPFLSSPVASVVAIASFPLLSCCLCCCHCFLSSPLLLPLLLSGLPFLSSPAASVAVKASFPLLSCCLCCCQGFLSSPLLLPLLLSGLPFLSSPVALLLSGLPFLSSPVASVAVRASFPLLSCCLCCCHCFLSSPLLLPLLLSGLPFLPSPVASVAVRASFPPLSCCLCCCQGFLSSPLLLPLLLPLLSPLLLPLLLSGLPFLSSPVASVVAVAPFPLLSCCLCCCQGFLSSPLLLSGLPFLSSPVASVAVRLPFSSPLLLPLLLSGLPFLSSPLLLPLLLSGLPFLSSPLLLPLLPGLPFSSLSSVASVAVRASFPLLSCCLCCCQGFLSSPLLLPLLLSGLPFLSSPVAVRASFPLLSVAVRLPFLSFLLLSGLPSSPLLLLSGLPFLSSPVAVRASFPLLSCCCQASFPLLSCCCQGFLSSPLLFAVRASFPLSPCCCQGFLSSPLLLLSGLPSLLSVAVRASFPLLSVLSGLPFLSLRCCQGFLSSPLLLLSGLPFLSSPVAVRASFPPSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPVAVRASFLSSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPCLCCCQGLSSPLLLPLLLSGLPFLSSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPVAVRASFPLLSCCCQGFLSSPLLLLSGLPFLSSPVAVRLPFLSSPVAVRASFPLLSCCCQGFLSSLSLPLLLSGLPFLFLSFCLLLSGLPFLSSPVASVAVRASFPLLSSSVAVRASFPLLSCCLCCCQGSLSSPLLLPLLLSGLPFLSSPVASVAAVAPFPFLSSCCRFLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0N0</accession>
    <name>A0A3R7M0N0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Coiled-coil domain-containing protein 85C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012064</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Adherens junction</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCDC85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002526">
        <property type="protein sequence ID" value="ROT69710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0N0"/>
    <dbReference type="STRING" id="6689.A0A3R7M0N0"/>
    <dbReference type="OrthoDB" id="10056395at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019359">
        <property type="entry name" value="CCDC85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13546:SF15">
        <property type="entry name" value="CCDC85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13546">
        <property type="entry name" value="RE60986P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10226">
        <property type="entry name" value="CCDC85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="408"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="543"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="585"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="353"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="476"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="596"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="652" mass="70134" checksum="84C229F1440D6FA4" modified="2019-04-10" version="1">MPAAADQHLEHHMAYPQHQGKTGPPRPGPHHGPPHHSSHPPSGSYGPQSGHANHVGYNHHGPMGQHAMPGQRGQPGQHGPPQQNGPQINLGQLRSQIGSTAQLGAPGQHGHPGPPGPLGPAGQHVPLSSHGSSLSHGPQGSHGPHGVPNQRVPPGSHIQAVPPAIQHKGPAPHGQYGAHIPHSTNIGNSRGHLDGPANEVRQPPAYPEPPRYPGPQTVHEDIDKHMSQVAALNGQSAQTLKQYSGAQGPGGGVGINGGGASMNSGDLGRLEEELSQLNRKDLVARTLRAEGEARELQHSIHVQAGELRHLRENQQRLTDDNQELRDLCCFLDDDRQKGRKLAREWQRFGRYTASVMRQEVTAYQNKLRELDTKQQELIKDNLELKELCLYLDEERNNAACSHCGHPLITRDDGDGSSSSTNADEPSGPPQPTADSAPTQSQSSEIPLARSSSRERLLEDTLSRQRSPMNEQVMSYIRSLEARVMMLETEKQQLGEELAKMDRIHPEGEGLESQLANKEKSVGSRPPQPPPYSLSHHLRAVGLGLTNRTPLGPGSAESDDELLDGPPPPLVSRPTAVAAAMRVLEVQEQLEGASHPPAVPPPSQGPPPPPHSSNTGSQLSAQDAALADGEKALLRQMCNVVWKKLEEVPSQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0U6</accession>
    <name>A0A3R7M0U6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002649">
        <property type="protein sequence ID" value="ROT68639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0U6"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="561" mass="64271" checksum="B89E244587188330" modified="2019-04-10" version="1" fragment="single">MNYKKLEEDQKTEEAEKKYKQCLEINSTHKAARDALSALDRKLGRVPETEEVQTVLRDLVDMENEFKRKRNDSESSTKSSRPRSLSPLSKKMAQQEGQWQPPPNINTTSSYLSNTSVSSIGVGVPGQDYTYSVANWQSSTVAPNVGMVGSVPACYVPPPTAYQHFPVQGSSGVPCSNREDEEYKARVEKFLKDIEGSRPIEKKERSKKRYRKESESRSRQKHSRGNKLLLFHSREEEAIPGLDSLEEKLSAYFKKVEASQREDSSKDSEIQNENEMKNYKQGICMSLKPHQISVSTSSFKKVHPAFRESDEDLDENASHVIDMARKCGKFEKLQLSLKTSKSNLEMSEIMPADSKERSRSPKGRTSYSKARSHKSFSRSRSRSQSSTRSSKKSPDRRSRGRTRTKSKSPPYHYEHVDCHRKYKVKSTRENQSLDRGKFNNQNSSGFGHLMPHDFEKKIEAAKSRLGAEIDYEVVENTFNKSRPRRWNTNSSGSPPYSKFSRTKTPNRWDSSHSRTSGKWDNARPKTPSRWDSSRPKTPSRWDSSRPKTPSRWDTSRPKTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1F9</accession>
    <name>A0A3R7M1F9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Integral membrane protein GPR155</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011435</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002445">
        <property type="protein sequence ID" value="ROT70280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1F9"/>
    <dbReference type="OrthoDB" id="2133778at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030514">
        <property type="term" value="P:negative regulation of BMP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051832">
        <property type="entry name" value="mTOR-Rac_regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22829">
        <property type="entry name" value="DEP DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22829:SF5">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN GPR155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT70280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="31984" checksum="F927FDE45F0EAF0F" modified="2019-04-10" version="1">MSRGQRKGVHYGVFDCHCLALKLSSVANLETNLNLPPVGCENGLANWLRESSSPDTRAELLGTVAVCGYGQLEFLKMNTTEDGSAVGGDSTGVPFLEEDTTDLSSVAFSNLYPAVIECFVIILCGYLAGRGNLISQTESKGLNTFVGTFSLPSLIFMSMAQLDFSSVNWLFLLSICISKATVFFLVILITLLVHRPMDFGKAGLFAIFCTQSNDFALGYPIIAALYGKSHPEFASYLYLVAPISLVFLNPLVLYSWRSENATKATRMERKAVLLGEKRMVVRWSCILSETFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1G5</accession>
    <name>A0A3R7M1G5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cardiac muscle actin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012580</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1G5"/>
    <dbReference type="STRING" id="6689.A0A3R7M1G5"/>
    <dbReference type="OrthoDB" id="9922428at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="41750" checksum="5257C5E0855023B8" modified="2019-04-10" version="1">MCDEDECALVCDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEESPVLLTEAPLNPKANREKMTQIMFETFSTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAIMRLDLAGRDLTDYLMKIMTERGYSFTTTAEREIIRDIKEKLCYIALDFENEMAQAAASSSLDKSYELPDGQVITIGNERFRAPEALFQPSFLGMESSGIHETVYTSIMKCDVDIRKDLYANTVMSGGTTMYPGIADRMQKEITNLAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQSMWISKDEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M750</accession>
    <name>A0A3R7M750_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bromodomain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001972">
        <property type="protein sequence ID" value="ROT73895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M750"/>
    <dbReference type="STRING" id="6689.A0A3R7M750"/>
    <dbReference type="OrthoDB" id="21648at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05513">
        <property type="entry name" value="Bromo_brd7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051831">
        <property type="entry name" value="Bromodomain_contain_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021900">
        <property type="entry name" value="DUF3512"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881:SF27">
        <property type="entry name" value="BROMODOMAIN CONTAINING 7_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881">
        <property type="entry name" value="BROMODOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12024">
        <property type="entry name" value="DUF3512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="8">
        <location>
            <begin position="79"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="548"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT73895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="629" mass="69340" checksum="B45E4BDBCB2B885D" modified="2019-04-10" version="1">MEKIPLKLKLKLGSGGPSTPEQKKSEKVEEEVTDEPPSKKQHVDVSASSATPKDLVQGKGKNASAALTQLLEYLLKQLEKKDPQQVFAWPVTDAIAPGYSSIISQPMDFSTMKQKIEDNCYTTLKEFESDFELMCNNCMTYNQQDTIYYKAAKKLLHIGLKIMAPEKVLSLKRELPSMTTLSKEQLGFDINPLPSGGGEMEMAAEVEQEESMEVDVDSKEPLSKFEALQDDMTSEEILEQVQTAAGEAAEKLTLKKPASTLGFLRQRGDGTTTLSFLTGCEGNDPNLKEKPVSLGLLTGKLTQGSSTLHNYRDDKRNMAKPVKPLYYGSYSSFCPSYDSTFANLTKEESEMVYATYGNETAVQYAESICDFSQDCDMAMHLVDQLLNLLTHQQHSRTKSVIEERRRMQEEEERINSLLCPSGEMGSQYASGDQKGNSTVDFSALRTLSDLGIDTNFLGEFEEMEKRESVINSQLEENANLLESLAKEQKERLSRPAPTNLNNVPNPSSKELNLVEKVTDGLTMVAKQVTPGALAPVPIVRRAMGITMHPVTSEPSEQIEVDIEGTSSQEEATPPPSGSNGSQGDQKNGSTDLESQLRHILNQTDATSPPPVVQGSTDMTDKKLKEILGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7Z7</accession>
    <name>A0A3R7M7Z7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001879">
        <property type="protein sequence ID" value="ROT74536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7Z7"/>
    <dbReference type="STRING" id="6689.A0A3R7M7Z7"/>
    <dbReference type="OrthoDB" id="2156856at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.80">
        <property type="entry name" value="Hypothetical protein, similar to alpha- acetolactate decarboxylase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34988:SF1">
        <property type="entry name" value="DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34988">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117856">
        <property type="entry name" value="AF0104/ALDC/Ptd012-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="148" mass="15762" checksum="6E4C0206E6489A17" modified="2019-04-10" version="1">MASPRQEGQSSSLKVHMLRLTPGQEVKTSLEEYVAREAKNGVFVMTCCGSLTSATLRLAANEEGVTNKVKTFKQHFEVLGMSGTVGRGGTHLHVSLSDHDGRSFGGHVVRDLVVFTTMEIALGEPTGLALGRSADAATGFDELTLTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8L4</accession>
    <name>A0A3R7M8L4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT74996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8L4"/>
    <dbReference type="OrthoDB" id="6375802at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018571750" evidence="3">
        <location>
            <begin position="17"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="283" mass="30438" checksum="4DDAFE167E0235AD" modified="2019-04-10" version="1">MLFVTALLSLSTLCAATEDKPEAAMLRQFGPYGRSPDFQRNSRNDRRRPNDDYKLDDLYANHNFEKGDFDRFGDLGHGGQDFGDNYFGNDEGFPSGGSYRQQDNGVRSGGSFERISRPGLNRRAGYTDALDYGRRGIERSGGSSGNNGSIDVYSILALGLFAAFLGYIVYYYISVNGGGRSFEGLGGEGMTRILEDVTKGIERWALLELLPDALEGFDISSGYGGRGGYGAAEATAKRLSTPSPSSLSPPSSVSSRTSCGGASRTRRGARASGGEISARAWML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCA4</accession>
    <name>A0A3R7MCA4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001446">
        <property type="protein sequence ID" value="ROT78027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCA4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="881" mass="95244" checksum="352F156D2E2AE207" modified="2019-04-10" version="1">MFLFCLLFSDDSSDVRSEIAPVLAVGAVPYLWVLCHTCGCCAILYLWVLCHTIPVGAVPYLCGVPAGCCAIPVGAVPYLWVLCHTCGCCAIPVGAVPYLWVPIPVAVPYLWVLCIPVVLCHTCGCCAIPVGAAVAVPYLWGCAIPVRPYLCVLYHTYACCTVSVRAVPYLCVLYHTCACCAIPVRAVPYLCELYHTCGAVPYLCAVPYLWVLCHTCVLCHTCGCAIPVLLCHTCGCCAIPVGAVPYLCLCHVGAAAIPVCCAIPVGAVPYLWGAVPYCAVPYLWVLCHVVLYHVVLYHTCGAVPYLWCCTIPVGAVPYLWVLVPIPVGAVPYLWVLCHTCGAAIPIPVIPYCGCCAIPVGALPYLWVLCHTCGCPYLWVLCHICACCTIPVGAVGAVPYLWVLYHTCGCCAIPVGAVPYLWVLCHTCACCAIPVGAVPYLWVLCHTCGCCTIPVGAVDRKCCTITCGCCAIPVGAVLPVPYLCGAVPYYVGVLYHTCACCTIPVRAVPYLCVLYHTCACCTIPVRAVPYLCVLYHTYHTVRAVPYLCVLYHTCCTILCVLYHTCACCTIPVRAVPYLVLLPYLCLLYHTCACCTIPMYLTCACCTIPVRAVPYLCGLYHTCAGCTIPVRAVPYLLLLYHTCACCTIPVRAVPYHHTCGAVPYLCCTYLCVLYHTCACCTCAYLCVLYIPVLAACLLYHTSHSHCRAIVICTPFPHAEAHHCWAKPHAPSPRGNERSIRQRLRRTLTQRLFAKSTQYRETPSRQRRCGEPPCLRCSRGAARWLPALIPAAGLFASLGLRGLTKSRPNTQTGDDNVDEKDNSKSSQKSNFGVDAKLCRIAAGPLHLSPAQLARVTGGAGSNVVKHSRIKLSNFTLRTSSGQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDF1</accession>
    <name>A0A3R7MDF1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized oxidoreductase dhs-27-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001316">
        <property type="protein sequence ID" value="ROT78886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDF1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF58">
        <property type="entry name" value="CHK KINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="2">
        <location>
            <begin position="155"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="46261" checksum="AB52CEAEA2EA92CB" modified="2019-04-10" version="1">MASEPTSPTSPTTPTSPTDDHEATKEWLETILEGYHRSKNAEADLDLELREWTINPASADKEGFLSEQLSMTVNYVAEGEEHHAHLLAKLLPQDPFNRAFVIETLFDVREIKFYTEIKPELEEVERKYLTEDFLSSSWAPKLYYAKHKQASESILVLEDMCQHGYQVEDLTKGLSQDQIKSAITALANVHAAAVALEVKEKKPLKERYPYLLSMEQAVESFTCLVDRGLPLLLKFLESRKDYAAVREGLQKYQGQKMAADVFRKVLTPSEKINTLVHCDYWCNNLLFKNGEERTDCCIIDWQMVTYGRPAIDLAFLISTSLETGERRKHCPDLLSHYWEAFTSRLSKYGIGKESHKYSREDLEADFKAAQTMAGLVVVGSVDIALGFPAREERVLELLADLLKVGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDT9</accession>
    <name>A0A3R7MDT9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001173">
        <property type="protein sequence ID" value="ROT79948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDT9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="680" mass="73225" checksum="40C3112504C53FA7" modified="2019-04-10" version="1">MPKPFSAHPQLANASVPLVARLCSPVLLQSFHPWPSCSQRAAPPPYFRRTRSLGPPAQVPLPLLPPLPPFRTSAVCSFRPHPPPPHSTRASSRRPPPLFPTSALLALKRPDVPTPRDRRPCISPSRPFLPPRDNYVSGGAATLRPHKQQQYTHDALSQSVELPPCSRTDLTRPSPPYKIPFLTPRLPPARTLLPALLPLPSIPSQALLPPPSLLTSTRALLLPTLPPPTLLPTPTPPPTLLCRPRPSSARPSFPPPLLPPPFSRLTQFLPSDTLGSLPPHHRTHLFSPHALLPAFLTPLTCPPPTNTLPPPPPPAASARYPFLPNRSLPPQPPSPAAVLYPPPSSRPPLPPTRPPHGLLAPTYSSPTSPPPRVSSPHLLTPLPIPPPPSSPPHSGPPPSHSPASPPPTSHPPQPSLPPALLPQPHPPPITRQDLLPHAFPLPAAFSPYLPPPLLPPHAAFQPPFSLPFLPTTPPPHPPPRLLPHPSSPNDPPAHPPLLPRSQPLLPPHPIACLPARPFSPTFLPPAAITLPRPPPSSPPRPLLPEYLCEFCVVPLRLRPLARTLTSPPNPPPPPFSTYLIPSRPPSGSPPRLLARLFRPSSLLLPPPLRIPHPPPALSPRPSSPPSSPPPPLPPALLPYLPPPPPPPPSSPRPFPPPQPQFPPQFPPISRDFVSDQPMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHM4</accession>
    <name>A0A3R7MHM4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative mucin-5B-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020186</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003884">
        <property type="protein sequence ID" value="ROT61987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHM4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="756" mass="85949" checksum="65E6C4069E6BC599" modified="2019-04-10" version="1">MLRCTSHTTLRCYESHIHTTLRCYVTPYESHHESHHASLLRVTPRFAVTSHTTLRCYESHHASLLRVTPRFAVPSHTTLRLRVTPRFAVTSHTTLRCYESHHAVTSHTTLRCYESHTLRCCFAVTSHTTLRCSHHASLLRVTPRFALRVTLRVTPRFAVTSHTTLRCYESHHASLLRVTPRFAVTSHTTLRCYESHHASLLRVQSPRFAVTSHTTLLLRVTPRFAVTSHTRFRVTPRFAVTSHTTLRCYESHHASLFRVTPRFAYESHHASLLPHHASLLRVTPRFAVTSHTTLQCFESHHASLLRVTPRASSHHALRVTPRFAVTSHTTLCYESHRCYESPRFAARRRVTPRFAVTSHTTLRCYESHHASHTTLRCYESHHASLLRVTPRFAVTSHTTRCYESHHASLLRVTPRFAVTSHTTLLRSLRVTPRFAVTSHTTLRTSTLRCYESHHASLLRVTPRFAYESHHASLTSHTTLRCYESHTLRCYDTPLLRVTPRFAVTSRYESHHAVTSHTTLLRVTPRFAVTSHTTLRCYETLRCYESHHASHESTTLRCYESHHASLRVTPRFAVTSPPFYVLRVTPRFAVSSHTTLRCYESHHASLLRVTPRFAVTSHHASMFRVTPRFAVTSQPRFADFTPSSSLLNLPLPLFPSLPSLPFPPLVPKGLLSPRRPFAPRPILAPLPSLPSLPSLPTPLFSPSSAPLPLLPLTYTHFPPPSSVPHSPSSINSLHPSPIDSPFPPSPLPIILPIPPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJT3</accession>
    <name>A0A3R7MJT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ankyrin repeat domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_022191</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000520">
        <property type="protein sequence ID" value="ROT84600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJT3"/>
    <dbReference type="STRING" id="6689.A0A3R7MJT3"/>
    <dbReference type="OrthoDB" id="10257076at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="175"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="208"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="416"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="418"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="452"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="610"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT84600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="628" mass="67347" checksum="3BEC99B35B566169" modified="2019-04-10" version="1">MPLPSLLLSALFLYSLFIILLRVSSALRSSLHSFISIHSLLPTVILSLSLLFFSIPSSSFLVLTLPYFLLTMMPIPLFILPFASISILIPSPINTTVDTSFFLPQKDRPSRLPGTDTFLSSNSWRRTAATSTPETALLLPPADRTALHFAARNGHLSVVQFLAEKGGDLNARDCDGSTPMHWAGWSGHWRTLEALAASGADVDPVCNKGNTPLHDAASNGKLLAVGALIGLGASTSKKNKGGKTPQDLLGTTSADRVFSMAKESAAAEKERRKMQEEEMQKKYDFLQKKYDSKAAEAATLQKKYDSKAAEAATLQKKYESGGGGHPAEEVRLESGGGPAEEVRLESGGGRQPAEEGQVKKARRDRQRGEREAGAEREGFNAQIAGLEERIATLQSHLEEESRKNLALTTQIAEKESELTQAEVSPPFGSQGTAGVRAQRSQSSTQQVFHAALESELKRRDKKIEDLKSEEEDSLLKRMMVSAPRPDASLSPPRDPEAPGAGEPSAVGGRRRVRGAAGSGDTPPAAARDGAKAAAGGGDKPRQATGRKGKARKAPEDDEPLSAAGRDERPEAAGTRGKVRQRADRKAEGEVAAEGEVATRARWRGVASEESPQEDSDASTLEDESDESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK27</accession>
    <name>A0A3R7MK27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative RE1-silencing transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000487">
        <property type="protein sequence ID" value="ROT84846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK27"/>
    <dbReference type="OrthoDB" id="6347556at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="909"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1086"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1196"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="909"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1090"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1196"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1232" mass="138083" checksum="7C09F72B46AF7174" modified="2019-04-10" version="1">MEDHAEFASDWREATQRQGGRYTPSVLESTVDGSVVKGARRPYGSRVTPAELDSFIDMAIEIGSDEKDPLITLDEWGLKTEQHKYKCSACEAVSKTRLDIEQHIADMQKDHEEAVVVVLIGPEARGRSCPLCNDRFQRSHLFKHIRESHNTFFPLRCGYCVFMGQDHNQLRHHIRKKHGTSKYRIIDVSRILAENDESGEKSLLEDEDQSDEDIREDSAPQGNMLCPLCGKGLKTLRNLKKHVAQHSRQKQQCMLCPFTTTFPTQVRSHFRRKHPSHSPKWQKVTLDKGGSDALVEDVGPYLRLITRKYGVRQPKKEKKWMRQYRCPHCDYICSFNSSYNRHLRLHKGVKPYKCGYCDFHGREAYVVRKHCSKVHKGKEVLVENDKNFKAPYRFESRLKKENYEWTSCLGNEGLKSNVSPENESCQLNNGSDKELAGSRILSTSAMAAQSAVDCLDEKVLMAGSSASFAKKFECLTFKTLSVVAEDQVMNTLHVQQEQSQMRSSELEQMSEAVISSCGPNVPLVSQSVELNLKRTANLKRQMEKVVTDALGFEESSSKKMLNYDVVAITNSSLQTETNSAVSSNPEICNFRPNFELQPENQSVKVKTFKVKHAPQSKCVNVNEIWTDDKKLPNTELEPEIGNTNVNRVEASLDSKMCEPSFCSISSVSLDCDDGSDNTVVIELCATSNESFTVKEVRGFKKREKLSHKNSEESVSLYVDTKRMNKMHQSLPVQSEKAVASLSKDFSIIEPTTSKKNVNKLITSETTKIGNSEASPSNGLENTLHTHIAFLTDSLVQRLSSPISATPGVMTRDLLGLDYSNSDYFSSEKVRHMMKKKSGGRVKCNVCGVTTTYRAFYKHAKKHFHIKPFKCGYCSYRSIEKSKIRVHNTFCHPSRPCIILKLSPETAGITTDGTQQTSGKVGQPVEGRPPHRTNSVDDETFITFPDPVGSVKDSNATNICNKISPSNSNSCESQVSINKKAADKIVDHHSPSTTSTVVPNVSAGPSTFHCPICYKQLQFHTPSIRRHLYSHYGYKPYKCGYCNFTAIGQNEIRAHHVTHGFTTAPKVESSGITMPTGLASYVSELLGQQRGSRKPQRKRGQVAEHQLLDETSESEREPTETQQEPTDLMWTEMASKEELATIYFTPQEQPQQALVPTPNSEPQEGLDLPVEAGPLTQPLEPVDLYSEAAYAVQVLESGQNPGPGTSPTRQLDVGGHSYSQFDSDQVCVVYLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKC8</accession>
    <name>A0A3R7MKC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003346">
        <property type="protein sequence ID" value="ROT63996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKC8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="45075" checksum="21778655888B0FB2" modified="2019-04-10" version="1">MPYFSPHFLPITNKPPPKPHNPPYGHMTTHNRPPHHHNPLTPTPHRRNPSSPATPHRRNPSSPPPPHPAPTPHHTQPFLTPPTHNPSYAHTTANPSSPRPHTTLPPPPTPQPSFSRPRHTATTLLPRPHHRNPSFLRPTLQPFSSRPYHTPQPFLPPPTPHRRNPSSPRHTTTLPPPPTPQTFPSPAHTTATLPPRPTPQPFLTPPTPHTTLPPLPTHNPFLPPPRHTAATLPHPAHTQPFLLTPTTQPFLPRPHHTAKPFLLTPNTTTLPPPAHATPFLPPPTHTLPPPPTPQPFLPPPTPQPPQPFLPRPHTNPSSPRPHTTHPQPFLPPPFPRPRHQVAVFARPSAIRSVKGVLLLSQALSGLVASFVVAFPIHVISARGVFFRPSFTPPSPLPLIFLIPNDGLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MN04</accession>
    <name>A0A3R7MN04_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000029">
        <property type="protein sequence ID" value="ROT86050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MN04"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT86050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="536" mass="59404" checksum="4A0FA1EBBD034676" modified="2019-04-10" version="1">MVFGERVLVVQPDESNVTWKFGDINRGGVVDYREAAGVDCATPGRHSAGLAVLAYLVVAVGGQPNTGYVQVFLEPIPARGKCPHMLITWRRGSSPRIITSRAACSPRSSRMTQADDIRSGERQGPYPPAAPPPPPVARRVTRSSAPEQRIRCWRATGGAWVAGVLRAACGRGCHSTTHPDSRYAGKLDPWAAVTTQATKNCRQANRWRRLRLAGRQGGTQRRVVAFGGRVSPGTPTCPPRSLGAPQPAPDAQTWLEPMCRSGWRCVVSPWWSRAGWWRQPGGRQRGQPHTHHNKHRASRANQNFSPVITYVLRASGGSGWPFLVLRLATCMSISPARSQVQIPCKYTQKTHRESERRPTLLRYLNLPTAIPSYRWQHCPGFNPFPTISCHPLYNLCSTSTRTTFPLTPETFLILWHKHSYTIHLRITNKHQDFLPSFALPHGVCFTSRGSNLSVSSPLLLHVDEGVCWPAWCVSATLTLITWKSWARISIWWLTVGKIRSGRSVSAASEAINTYGQPSSRLRQGSPSTNCGSVEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MS41</accession>
    <name>A0A3R7MS41_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 10">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_013396</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 10"/>
    <dbReference type="EMBL" id="QCYY01002665">
        <property type="protein sequence ID" value="ROT68434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MS41"/>
    <dbReference type="STRING" id="6689.A0A3R7MS41"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT68434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="300" mass="32795" checksum="D883C07EFFBB103C" modified="2019-04-10" version="1">MTLRRATEMSGPRKFLVVGGWTPQADSSAENTRDSFSSFLSYARQNLPVEIGTTVPDGHQEEEAFCRDCHCHWEVVGRALSGSSDSQLKEAIVDAQQAGRKVIVRLCETSEDREEGRTDDVLFGQMKSLAASISDWSRVVIAFEALWASNTGVLATAAQVQEALAKLRHWLRANVSDKVANSTRILYAGSVSSSNCRELAQLEDLDGFLVGSAALTRRRSRDHFVARVSLVPVGDARGPQVDRSADPAASSAGMREEIGGDDAQSETIHLKGFHSCFGQNPVQMNIYRGLYVYKSLLSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N2U9</accession>
    <name>A0A3R7N2U9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001738">
        <property type="protein sequence ID" value="ROT75743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N2U9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="101" mass="11203" checksum="0E3AAADAB52AF24B" modified="2019-04-10" version="1">MASPHQAGSTAQDGHHRRGNGRPQARSPPRQPLRTAPSEGEREGRVQNIFRARSRGRRSPRKPGPGLTWSSIVVRRRVERQCPSEVEGAANHPLVFARVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7J7</accession>
    <name>A0A3R7N7J7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001256">
        <property type="protein sequence ID" value="ROT79347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7J7"/>
    <dbReference type="STRING" id="6689.A0A3R7N7J7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="626" mass="67493" checksum="B338223314F93850" modified="2019-04-10" version="1">MTLYSIIFLFFSFLILLSWNIHTLFSFIPLLLYCLIASPLSLSSLLSSLSLSLSLSLSPLSSLLFLFLYAPPPSFLLLSLFSSLLLLFLLLFLLLLSAFSFSSLSLFLFSLSFSFFLSLSPSLSPFSSPSLLLSFSSLLVSFSFSSPSLFSCLLSPLPSRFSFLFSSFSFSFSSLLLLSPSLSPSLSPFSFSFLSPSFLLLFLPSLSPSLPSFSSLFSSFLLLFLFSFLLLFLLLFLLLCYSLLFLLSLLRLLLSLLLLVFSFSSSSSSSSSLLLLPPSLPALSSSTPPTPPPLHSCCSPPPAPSLLLCPPFPPPPTSSFSCSFSTPFACTRTTNSPPSFLPDSPPSSPSTSTSPTSHSGTTSTPPPPPLPPLHTPRTSQLRLPGVLSVVVAGESPRCPPPSFSNASPVPIYIQRRMPPLSPPNPSPPFFAAYCLHSFTSSSVALLFPPPPYTSFSFILTFLLPPPLFTTFSILLLLFLLPSLHSLPPFSPPPPLSLFYLSILLLLLLRPPSPPSHLLLLFSLLLSFPLPSHLPLFPSTTSSTSLSFTTSPPSPPPPPRSSSPVLLLLLLLSTRPSFPSFSSSPSPPLSPPPPPRPQSPSLRATCCQAVSKALARLRCLTVYCHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NBD0</accession>
    <name>A0A3R7NBD0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_024341</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01000817">
        <property type="protein sequence ID" value="ROT82486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NBD0"/>
    <dbReference type="OrthoDB" id="6367049at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF54">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018618392" description="Carbohydrate sulfotransferase" evidence="11">
        <location>
            <begin position="28"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="108"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT82486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="467" mass="54726" checksum="93D15560B4C8081A" modified="2019-04-10" version="1">MAKLRWRPRFFLLVGVVLLASWAFVEEANRVPDMLRHTDLFDDWLLRNRNNISRYEIKKLGLEADSETYQRWLVFKLLDSLREGNVTGRIRDSRILDEYKQYQKWLSERTEGAGDPSGAAEGEGGHTEEQDYWQDPLAEDEEDVEYEDEDDEEESIELRLQKRRKSMLTSCAAREQTSATEVLASVRPRIGFFFDQKTSVCAVGKAGSSSWREHIHRVNGIPRDVLIPDDPRVKEFFEQPEEALYASIISSAKIISVRHPLTRLVSCYRSKFELGRPMKPYAPKKEAKFLAVKPQCARLADEVLHLLASRVTHTNDMIPEDTHVRLNLSEPINPAVKYDLTVYEGLYRLLKPHVLFSHFLKHVVHTHKTGTWNGHWGKYVELCAPCGLKYDYVVKLETMSEDLEYIFQKLGIPSNPNLRKNKSTRRKDFSKYFRYYRWISKELKREVFETFKDDLEMFEYTLPKNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NTJ5</accession>
    <name>A0A3R7NTJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002957">
        <property type="protein sequence ID" value="ROT66332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NTJ5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="41914" checksum="8CA79EDFE7AE579A" modified="2019-04-10" version="1">MTTEETDLKWLVGGSVSLALLSHPICLSLSLSSLLPPLFLVFHLPPFCTIFSLPPFYSIHLSFFHTSPLFKCLSLSLSNLSLFLVFHRPPFSFIIFLPLPSIPLSPFIPSSSIPHSLSCCSIYPPLCSVFYFFLFLTSSFVPIPLYPFLPCFHISYFFLPCFSLSLSSIPSFRTPIFILLFLLTSFRRSVFASSTFFYLLFLSFSSLSLPLLSISITPFICPPSSLLSLSLSLSLSPTLFSPSALSLSLSSLSLYSLLSRFSLSLRSLTSSIISLLVPALFSFISIHPLLLSFSSNASSLFPPFISTSLWRAVRWLRPLCFSPWRSAFFSPCAGRTVASRDVDTRTHIDMVPAELVSNTDVGTADDGYTPVSASQVPSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NU97</accession>
    <name>A0A3R7NU97_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002879">
        <property type="protein sequence ID" value="ROT66870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NU97"/>
    <dbReference type="OrthoDB" id="297496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="17491" checksum="3C243BC36AEE2CAB" modified="2019-04-10" version="1">MMSFKQWLALLGIYTIYMLIGAAVFISLEKDNEMAGREELLDLKGRVIDFVTGLDNESRPGAEVVLVDVGGVCGHDFLAAEADVPLTWINQLLDWPAGFLYCWIFGQDEAKNERKRTCLRLLPHHRSFSLSEVCRESAPVDLQRKWHRKKLAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NVG0</accession>
    <name>A0A3R7NVG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Solute carrier organic anion transporter family member 3A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014092</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002757">
        <property type="protein sequence ID" value="ROT67804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NVG0"/>
    <dbReference type="OrthoDB" id="5062115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF159">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 74D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="636"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="640"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="726" mass="79583" checksum="B90C33467B46F0E4" modified="2019-04-10" version="1">MPPPSPLPRAPASIVVHATRSPLSYLEGITAPSANPDDGRSQQPRDMLARPFSAASVEQRHFTLNGDVAKHVRHFERGEAPEGKEIRPKDIEKTSTKETYYGAMVGSVTRWEPGVGRDQQHLAVTDHVAGLDPPIIPLSLPTLSRPLPSHAHTPRPAEDPDGSVEETPCLEEHRRGRERTTSPCHAPLQPPASVRPESLPGLDAPANGRQHNHHRAPAPTTSSALEVHPGTAAHTSTNGTRKRPPPILPPALATPDTWAEPEETAPLTPATNGEVARRGLNGVVVKKMAPVEEAVIEEEVEEEEETALRHEEEVEEEEELKCGLGPCCTPVWLQKYASKQMFLFVFCLTSVLQGMYYTYVVSILTTIEKLFQLQSKTTGIILSATEMGQIGGALLLTYYGGQGHRPKWIGWGIILFAFFAFFSSLPHFLFGDTILKRFQDSTPSQDNPLESANTCEVPGWSAPELNASLAAAGNATNDSCDSPDSLSQVVMSILFLSLLGVGIGQTAAYNLGIPYIDDNIASRESPIYFAVTSGVRILGPTLGFVLGSFCTRLYVDPFQDPSITPNDPRWIGAWWLARGPLERERQTRFMTDRRSHVSCCRSLVLGHWHRHGTRRRPPCNAPGNHVRVLLITRKRGSSPQPIPYSTPQLQPPSTPLPTPEHSPNPTPTSTPHPQTPFTQPPLQTPTKPPSPLPPPPNPPQPPTPHPTTNPLLVPPKAWWWCPWRCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NYM0</accession>
    <name>A0A3R7NYM0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Complex I-39kD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase 39 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_011273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction. Interacts with BLOC1S1. Interacts with SLC2A4. Interacts with CLOCK. Interacts with RAB5IF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I NDUFA9 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002425">
        <property type="protein sequence ID" value="ROT70444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NYM0"/>
    <dbReference type="STRING" id="6689.A0A3R7NYM0"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="6">
        <location>
            <begin position="59"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00040720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00042000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT70444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="45360" checksum="744A9C5D41BE926E" modified="2019-04-10" version="1">MALQKNVFSLRYGLNARLGAVVAVQHRHSSDVRFLTRPEVSALKKGRGGRSSFSGNVATIFGASGFMGRYLCNRLGKTGTQMIIPYRGDHYDVRPLKLTGDLGQVLFIPYHLTDEEVIRKAVKHSNIVINLIGRDWETMNFSFEKVHIEGAERLARISKEMGVEKFIHISALNSNVEHEGYIVKGGSQFLKTKGLGEQAVRAAFPEAIVFRPSDVYGQEDRFLRYYAGLWRHQGRLLPLPKAGKGIWKQPVYVSDVAQGIINAIKDHEAVGKTYEAVGPRRYELVELVDWFHRVMRKDENYGYMSYDMKWDPFFKVKAMITEYCPSWPVNTLTRDKVEREAVSDTTTGLPTLEDLDVPLTKMEDRISWELRPFRAANYYDEEVGEFEPPAPPKYISAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NZ77</accession>
    <name>A0A3R7NZ77_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002369">
        <property type="protein sequence ID" value="ROT70935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NZ77"/>
    <dbReference type="OrthoDB" id="6374122at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="297" mass="32543" checksum="DA7878026A44B98D" modified="2019-04-10" version="1">MPPPPREAALASPASSAALSVSTDVARFLGSSMSSSESLAFFELLLRWGVLCLVVLLVDSAQVCQEVNVTCKTLLPISEEADHLVALVGVLPRQGVWGVHFELEREKQVLASFNMSRTEGKRGTTITYSDHLAVSCRNRAALEVPSPWPEDWFLCGVKFILFNISQHLIRVSWKADSAGYQDLATDVCNVNYLSDVSFSASSLRHLPTPMLSLRCADEEPGRSADEEPRDGSESESAVPPVFQLCVAGLIVLLALVLSAVDLFLILSLRKRLLTPTMTAIEAVGDDYVPRRRKNRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P2K7</accession>
    <name>A0A3R7P2K7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002003">
        <property type="protein sequence ID" value="ROT73698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P2K7"/>
    <dbReference type="OrthoDB" id="6347073at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="744"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="865"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="8">
        <location>
            <begin position="235"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="474"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT73698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="892" mass="101134" checksum="45207B299799682F" modified="2019-04-10" version="1">MGCPAIKTKCQRKTLLWNAIICLILAGPAVSVKVLNVEQNSGHAAVSGSLPPDAGAVLKDPRFPSAADYTACLRFQFAKLKKVNILLRVSTNATRPLLQLDLNVDQIRMVVDYQQRYVFLEKGLEARRWYAVCLLRERAALRVTATLDGQVVGVNALQETEAAKATDLSFGFVDPTLNPGGSFAGNVTQFNLWKRILNEEELKEVASCKSNVQGNSISWEDDWVFQSPVQYDLKQEDLCFRESPSKFQVFPAMDHGQSTYLCGALGGSLLTPKHMIEVTRLYLTAQTQRQDCDGIWVGATDEGEEGLWHQPRSGLSPATLPWAFGEPDGLRYENCAGIEPEGVTDENCEMKRCPICSMTERVAMTLRGSCEADLHNTKYTMLLKDEEFFFEGYGDYTISLKNGAWLWMNASRNETLAQMNPSRYNYPFGRQRWQLRSAVCGQEAGQVRQLLLTRCQGEQFTCDDGTCIDLNQRCDKKHDCLDFSDEVGCEIVRLPPEYKVFVHGLKGGNETLRIQAELNLENLRVDTHEMALETSLNLTLIWLDARLTFVNLKPRIRRRLQRLRGKGQHHVLRQGRPTGTDGALAQEVNLYSGSDNPIVSSNKYHASFTCNFDLSRYPFDQQTCDILIQLRDDVKWDVDGSLVQYVGASLLEYQLGTATILPELVTGDDSVHIPLTRRANPVLMSVYLPSLAMLSVALLTLFFVMNNFEVRCITTLTTLRLQINLYTDSLASLPKTSYFKLVDIWLLFCIFLTLLIIFVHAAVDVRQHSEKHRASERPPDLEEKMLAGSFGFRARLTASRNRVARRLRGPSLSPDVDKRRLRAWEAEVLGTPPQRTRWCLWCWRGGWCHRFWCCRGGRRMTARSVVWLGRFLVAVLFIAFNIYYWLTAYNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3Q7</accession>
    <name>A0A3R7P3Q7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adducin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021863</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldolase class II family. Adducin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004676">
        <property type="protein sequence ID" value="ROT60612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3Q7"/>
    <dbReference type="STRING" id="6689.A0A3R7P3Q7"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF21">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="2">
        <location>
            <begin position="41"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="160" mass="17183" checksum="236DF38BD317F4A7" modified="2019-04-10" version="1">MLSRRASAFGRRLARTFTSASAKPYAVPEGHWGANRAARLELAAAYRGLDQLGLNEGVCNHLSVVAPRADGAGEAMLVFPFGLHWSEVTASNLVMIDPDAGLVEGDTDPEVTASCIHLGIRMVRPEAKVIMHTHQPHVTALEITGALRSLSKKAKGWGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5I4</accession>
    <name>A0A3R7P5I4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras GTPase-activating-like protein IQGAP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003989">
        <property type="protein sequence ID" value="ROT61787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5I4"/>
    <dbReference type="STRING" id="6689.A0A3R7P5I4"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903479">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.506.10:FF:000004">
        <property type="entry name" value="IQ motif containing GTPase activating protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="338"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="768" mass="87794" checksum="3286ED0E14B7A81A" modified="2019-04-10" version="1">MVDGNDSAIVDILRSPDLAHLRIQKSHLLGVLTMLKKSYREKESSTVTCPWIPYSLTDGSKVYLNLANGGYQWEKPEEVVMAHQSRYLTLVDLEDAVMVIMQQEANNKRLDQLMVRLQARARGWLQRQRISRLKAAALAIQERQVVVIQRAWRAHKARVDLRSLTHQANPPLSVICKFIHLLDVSEKDLDEEFKLQRTKSDMVKTIRHTHQLETQVDELDVKIGLLVHNRITLQDVLPADKENVNPNVPETKTRRSRKGSKDTLKYGSMRTQRGLKAFKKESREKLLSYQHLFYLLQTQPHYLATLIFAIPPGKTTKFIENVIFTLYNYGANDRDNFLLLKLFKTALEEEIRCKVLRLSDIVSGNPLVVKMIVSFNRKGAGQASLRDMLGPLIHRILGDSGMQINTNPVDIYKSWINQLEMHSGQASGLPYTVNQDQALQYPEVQKRLAQAITTLKEVTLAFCDQITTNRDVIPYAMLYMAKVMRQALQRRFPHIPEKEILKVVGNLVYYRYINSAIVAPDAFDIVTVSPDQKLNNNQRRNLASIAKILQFAASKKGFGDEAITPEVPEPFIIECHEKFKNFFRHCCEVEEPETVYNVTQYSEANAYCQTHHLHHNPGPDERIIYRKSVRPTNSCWTMRRSLPQTATTLSMSYSLTLGRDPSSPCPRGRGSSRQDGKCVWHSSTSFDVTETAEEKDSKDSNKMFSRTKQLLVDVLRCVEGSSIGQLVTGPTLSPQEERYRSIIHTRTRQEHQAQAQPHGTQPLQLLPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5P1</accession>
    <name>A0A3R7P5P1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003931">
        <property type="protein sequence ID" value="ROT61911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5P1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="620"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="660"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="692"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="947" mass="100892" checksum="66BC1488C6F2296B" modified="2019-04-10" version="1">MIGKGEKLRARDARRTGTRVPSSRPHPANRHPSLLTPPFSSHAPPFSTTSPFTLTAFLTPLSPLSPTRLLSRPPSHAPFSPLSPHAPFYPSPPSHPSLLTPPSSPLFLTPPSHALSSSTPHLFSHPLVLTAPLLTPPSSPSLLTPPFSRPPLSHPSLLTPPFLLERPLLTPLSSRPFLTLSPHSPLLTPPFSPSLLHAPFFHLLSPLTSPPFSPLSPHAPLLTPPSHPSLLTPPSHAPFLTPSPHPPSHPFSPLSPHAPLLSPLSPHPTLPHPLSSRPPSHPSLLTPPSHPSLLNAPLLTPLSSRPPSHPSLLTPPFSRPLLTPPFSPSSRPLLTLSPHAPFLTPLSSRPPLTPLSSRPLLTPSLLSRPSPSRPLLTASLLTPPFSPLSPHAPLLTPSLSRPLLPPFSSLSPHAPSSPLSPHAPLLTLSPSSPLSPHASSSRPHLTLSPHAPSHPSLLTPPISPLSPHAPLLTPLSSRPPSHPSLSSHAPFSTPLSSRPLLTPLSSRPLLTPPPHPLSPHAPLLTPLLTPPSSPLSPPRPPSHPSLLLTAATTTSPSGVDRRPRQRGFRRLLVRLNCGISRSPSLRPSIPSLSPFSSLASLLSLLLALFRVWLSPLSLSLLWLSFSLLVLLFSLSLWLSFGSRSLPFSLSLLFSLLWLSFGSRSLPSPLSLLFSLLWLSFGSRSLPLLSRFSSLFFGSLSGLALSPLLSRFSLSSLAFGSRSLPSPLSLLSSLLWLSFGSRSLPSPLSLLSSLLWLSFGSRSLPSPLSLLFSLLWLSFGSRSLASLLSSLALFRVSLSPLSSLASPLSSLALFRVSLSPLSSLASLLSSLALFRVSLSPLSSLASLSLLSFGPSPLSLLWLSFGSRSLPSPLSLLSSLLRLSFGSRSLPSPLLISPRVRVSNMSRKLVGEAVITRGDYFHQLFLTFSPSISYSSPISPFPPLLPTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P966</accession>
    <name>A0A3R7P966_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003264">
        <property type="protein sequence ID" value="ROT64335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P966"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="43768" checksum="D7D8CFCDA02A76B9" modified="2019-04-10" version="1">MERRFACERPHGEIACKNYKKSSRAHHTTETGFFTIKCIFKVSACLFPSSSSPSFLLLFPPLLPSLSLSLYNPLSLSYPSLSFPLPLSLTPLISLPYPLSLPPSFSPFFSSFPSPSLFFPCLSPSLSFFPPLLFISIPPLLSVLSLLASPLLFPSFPSSLSITPTLHISFHHFFFPPPLFISLPSPSLSPSLPFFPPSPLSLFLPFPLSFSLFPSPLFSFPLSPLFSLLPLPFSSSPLPLFSSPLSPLFPSFPLPLSLLPPLPSPSFLSLSLLPSPFPSSPLHSPFSPSSLPSLLFPSPLLSFPLSFPLSPLFSLLPLFSPSPPLPSSSPSPSPSFLSFPLLSPPPLSFSHSLSLLLSFPLSPLFSLLPSPCFSLFFSSHSSEGHIRASRQRSFSFFFFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9B4</accession>
    <name>A0A3R7P9B4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9B4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="42481" checksum="1CEDA678484A1A3B" modified="2019-04-10" version="1">MHVQSSPKIVVVFVLFFLVCLIDLSICTSIRVCIYYFILIFIYLFFIFLSFIFICLLYFFKFSLFHYLSSHLLLSLSLPLSSSPSHLLPFSLPLSSSSLFSPFPSSPIFPLSSPSPFSPSLLFLNLPPLPFIPFSPSVLFLGLSLSLPLPPSFLSFPFLSLSPPLPPSHPSFPFPPFPFLSLSFFSPSLLPFPFLSSSSPFSPLLILFPFLSPSLLPFPFLSPSSSSPSSLPLSSPSFLSPSLLFPPLSSPPPFSPFSLLPLLSSSPFSPLLLLFPFLSPLLLSSSLPSHPLPFHPSPPPSSLPLSPFPLSPSPLPFSSSFPLSPPSHPLPLSLPLSPFPFSPSLPFPFLSPSLPLSLPLSSSVLSINQILSDRLPPTAAFHLAGWALMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAY3</accession>
    <name>A0A3R7PAY3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative D-beta-hydroxybutyrate dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003068">
        <property type="protein sequence ID" value="ROT65578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAY3"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF36">
        <property type="entry name" value="D-BETA-HYDROXYBUTYRATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="333" mass="36595" checksum="B5424EC18DBD3560" modified="2019-04-10" version="1">MNISIAICGLPSVTVLLHCKMLWTMDKASRLLFWCGLSLLLAGVSETVIPLSFWVTFSGAFLVLGNTYLLLASFKGFHVFAGCLRAGGGGAHQLRSSASPRLQVIQLDITRDEEVNEALREVKSLLSPRGDREKELWGLVSNAGISTFGAVEWTPLRTFREVADVNVFGHIRVIKAFLPLIRKSKGRLVNVSSAEGRFTAPFVAAYELTKHAMEGFSDCLRDYFSGTKLHTAERAGALAGSLWSAMTDEVRAAYGGGSFGRVVSSMQSVTNTGLVDLTTAVDAMVEALTQRFPQARYTCMDSSLYARGLVAQHLPEWIYDFLYITEARNAWYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD04</accession>
    <name>A0A3R7PD04_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">phospholipase D</fullName>
            <ecNumber evidence="1">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_020340</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003970">
        <property type="protein sequence ID" value="ROT61849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD04"/>
    <dbReference type="STRING" id="6689.A0A3R7PD04"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024632">
        <property type="entry name" value="PLipase_D_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF60">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12357">
        <property type="entry name" value="PLD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="9">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="9">
        <location>
            <begin position="553"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT61849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="710" mass="80644" checksum="4A87605DFB955A36" modified="2019-04-10" version="1">MSSEAHRTTEHDEAHTGDNDDPLPEEGTDSEDSPTVQETLSEDNKVLSSDEAQRLTQESLAEDAIIHLPEEQALDGTLSSGAGSKPKVIQVPNAYFPACRGGSVDFYHDAMSVPVPPFGDSEGVFAAIEKALLRAKDFIFVIGYSLWPDINLRREENSPTLGEILIQRASEGVEVKILLWREIIPIFKYAELRRKEIKEYFCDSEVELVFAARHKKPGAGFLQHKKAPFMWAHHQKSLVLDSGTGEILAFLGGLDITKGRWDTPDHQLFSTLDKEHKDDFRNLFIAVSPECGPRQPWHDVHMRVSGPVTRDIFQNFRERWEKERRRIANKEDVDDYYGSYDPEPTQIWSKIMTNAATESGGTQWVMQLLRSIEETSADFERKASPGLVDIEGCWVDQSIQQGVIEIIRNARGYLYIENQYFVGSSKYWEKEAKVEAKNPIPYEIVEKTIQKIRAGEQFCSYIVIPMLPEGNIEGHVCSRIAKKIMHGQLQTIQMMYRRLAKELQAIGSDAHPTDYLVFLCLGKQEAKPDYAAGGAKEPEPGAKEWKWHDLSHFMIYVHSKLIIADDCYLLAGSANFNERSFAGNRDTEIAALVQQTRTVDGAEEVVCDGQIHDFRRRLWAEHTWGLSEADSSLKDLASLEAIRRVKELSKDALRAYVRGAEENSMRLLRFPVDITRDGAIQAYDDLPFFPDFELMVIEDIMDEMTIEECM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD88</accession>
    <name>A0A3R7PD88_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative transcription factor hey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_020125</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HEY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003856">
        <property type="protein sequence ID" value="ROT62048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD88"/>
    <dbReference type="STRING" id="6689.A0A3R7PD88"/>
    <dbReference type="OrthoDB" id="6371181at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19748">
        <property type="entry name" value="bHLH-O_HEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000012">
        <property type="entry name" value="hairy/enhancer-of-split related with YRPW motif protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050370">
        <property type="entry name" value="HES_HEY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003650">
        <property type="entry name" value="Orange_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10985">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07527">
        <property type="entry name" value="Hairy_orange"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00511">
        <property type="entry name" value="ORANGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158457">
        <property type="entry name" value="Orange domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51054">
        <property type="entry name" value="ORANGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="11">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Orange" evidence="12">
        <location>
            <begin position="256"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="305"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="50824" checksum="A2E7B8A9AB93A586" modified="2019-04-10" version="1">MGVTREVSRSPRHDSGGWEAAPPGGHHRGHGTHHLTWRLPRGTAPPATASAGRFRLYAVLAYGPGKLRRGPPRGSPKCRGRCGSYSRRTQGRIFRSGRLRVRPGWRVGAPQAACRVRSLVCAAILCLNPVPCGELRPSTSLTANICNMKRTLSESECDDIYSGDEKDGDDCSSSGGVSRKRRRGIIEKRRRDRINNSLSELRRLVPAAFEKQGSAKLEKAEILQMTVDHLKMLHTKGLDALAYDPNKFAMDYHNIGFRECAAEVARYLVTIEGMDIQDPLRLRLMSHLQCYAAQRDLANKQAASSWGWGSSQPAAPAPPSYTPSSSLSGFQGHVLPTHGASTHHPSAGAHHTAAPAVGLDQSHGMSAFSAPSSSGNNDGGVSGCSLGSSQVPRLPTTGAGAPHVPAVSMATAAGQHTNYHLNLNAHAFPATNPAPTISNISLSANTSSTLNPAYNPGLQGGAPGVKPYRPWGAEIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEX8</accession>
    <name>A0A3R7PEX8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative ceramide synthase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_012715</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="ChEBI" id="CHEBI:57817"/>
            <dbReference type="ChEBI" id="CHEBI:67033"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:36548"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002601">
        <property type="protein sequence ID" value="ROT69128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEX8"/>
    <dbReference type="STRING" id="6689.A0A3R7PEX8"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000020">
        <property type="entry name" value="Ceramide synthase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="13">
        <location>
            <begin position="137"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="365" mass="43746" checksum="8D4F8C0BD40C7909" modified="2019-04-10" version="1" fragment="single">MAAWMWHKFSSWFWNPDVWLPPNYSWEDLVPNEKIRYANWSDLWTYPIFMAFLAIGLRFLVLNKLVYRHIALAVGLRDVKPRPVVPNETLEQLFLRSKKQPPENEICQCAKQLQWTERKVERWLRQRQAMTRVNKFTKFMECAWQCTYYTFIFFYGLYVMSDKSWLWDIRNCWYEYPNHSVDIDVWWYYMISLSFYWSMTFTHFFEAKRKDFWQMFIHHMVTIALITFSWTCNLTRIGTLVLIVHDCADIPLQLAKMSIYSGHKAFCDAVFAIFAILWIITRVGIYPLWIVYSTAIEAPTILPMFPAYYIFNSLLIALLLLHIYWTYLILRIIATTISKGNVEDNRSSSDPSEVSEDNGEEKKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF05</accession>
    <name>A0A3R7PF05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003343">
        <property type="protein sequence ID" value="ROT64006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF05"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="591" mass="66193" checksum="2AE185197DF077FA" modified="2019-04-10" version="1">MSLYTPFRKFHSPYRESCHTTSEVFHTPYRESFTTTHTYRVLPVHQQGSPTPTIQGLPPPTIQSPSTHHTESPFTHHTGSPSTHHTESPSTHHTESPFIQGVHHTGSPTPTIQGLPPPTIQRVLPHTIQRVLPHTIQGVLPTIIQSPSIHHTGSPFTHHTGSPSTHHTSHIQSPSIHHQGVTPPTGSPSTHHFFPFLLQDTHHTGSPLHTPYRESFHTYRESFHTPYRESFHTPYRESFHTPYRESFHIPYRVPIYARYKESFHAPYRESFHTPYREFPTITNTMQGAHLYTISGVLPCTIQGVLPPTIQGVLPCTIQGVPPPTIQGVLPHTIHNTIQGSPSNTIQDHTIQVPFTVFHTIQGVLPHTIQGVLPHTIQGGVPPPTIQRVLPNTPHTESHSHHHNREIQHPNHYRGHCPTPPTINRDPSHTIQEQSYPTHHTRAFRPSTKDPFQSPYRDPFTHHTAGHSAPPTNEQLSSSTTINTEVVLFTHHYRESFHPTIARESLSPPIHGSPLPHTIAGSFHTPSQGVLPHTISGSCPHTHTGEKSLPCGTNPGSSTPPPTQYNRESFHTNHTRSSLPTHHYRVVPSHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFG8</accession>
    <name>A0A3R7PFG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LMBR1 domain-containing protein 2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017323</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003199">
        <property type="protein sequence ID" value="ROT64756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFG8"/>
    <dbReference type="STRING" id="6689.A0A3R7PFG8"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="601"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="677"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="637"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="708"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="718" mass="80690" checksum="B47C52C00E7D8F90" modified="2019-04-10" version="1">MGVGPLVVEVLVTFVVAAVVLFHYGNWYRHHIVVTVAVLVAWYFSMLIVFILPLDVSNTIYQNCLPDVADPLKVQKLLPSTPSNLTNETSLLSDPIDDGSIANISVTTVAPSPVPPPIPGCHKPWSFVPAGVFPVFWRVVYWTSQFLTWLILPLMQSYTKAGDFTFSTKLRSALIDNAIYYGSYLLIVGILLLYIALTNLELDGAKLRAIAASASNTWGLFWLVLLLGYGLVEVPRSIWHSASTLHTLHHAYFRAAKLSQEKAEANEHVSDLLQSMRALGGSIGLGHPLRAHMDVIENKVPSELLDRVRQHPTPDSPHADVPSEKALVRLHKQLIKALQNQRRVETQWGLLVENIAYLEDTHRNAVSHDTSFKHSTPPRRHYLISYVYTPTVEWLWRCRIRGYLLRSVAVCCALVSVAVVWSELTFFSTSPTISLFAVFVNLAKASYDYFTIEVISSLTMAYIALCAYSTLFKIRVLNLYYLAPHHQTDEYSLIFSGMMLCRLTPPMCLNFLSLIHMDSHVIKVHTDETHYTQIMGHMDVIKIISDGFNIYFPMMIVALCLATYYSLGSRLLSALGFQQFMSDDDLTSDLIEEGKTLVNRETRRRQRQEDNAARRREFAERFGGGESSASMYRSARQRAEELVRPMKREDSSESAHLELLGGSDNIADYSSHTTTSSLTLEDEMEAGRGGARISGFSGLAQYSRARTHKPDKGLFDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHS7</accession>
    <name>A0A3R7PHS7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Solute carrier family 25 member 32</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Mitochondrial FAD transporter</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_014967</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Facilitates flavin adenine dinucleotide (FAD) translocation across the mitochondrial inner membrane into the mitochondrial matrix where it acts as a redox cofactor to assist flavoenzyme activities in fundamental metabolic processes including fatty acid beta-oxidation, amino acid and choline metabolism as well as mitochondrial electron transportation. In particular, provides FAD to DLD dehydrogenase of the glycine cleavage system, part of mitochondrial one-carbon metabolic pathway involved in neural tube closure in early embryogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>FAD(in) = FAD(out)</text>
            <dbReference type="Rhea" id="RHEA:76535"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002871">
        <property type="protein sequence ID" value="ROT66967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHS7"/>
    <dbReference type="STRING" id="6689.A0A3R7PHS7"/>
    <dbReference type="OrthoDB" id="428293at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015215">
        <property type="term" value="F:nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015711">
        <property type="term" value="P:organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000025">
        <property type="entry name" value="mitochondrial folate transporter/carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="114"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="221"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00079992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT66967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="321" mass="36088" checksum="E4CAF20DE5B6C3C0" modified="2019-04-10" version="1">MSRSKKYNNPFAGVRYEHLVAGVSGGVASTLILHPLDLLKIRFAVSDSSATATKPHYTGLTQALGQILRHEGIKGLYRGVTPNVWGAGSAWGLYFLFYNMIKSWFQSGNSKVHIGPSLHMVAAAEAGILTLVMTNPIWVVKTRLCLQYTDGTGKVLAESHRYNGMVDAFVKTYKYEGVRGLYKGFVPGVFGVSHGALQFMAYEEMKAKYNRYRNLPIDAKLTTLEYLGFASLSKLFAAVTTYPYQVLRARMQDQHAHYDNLRHCIKETWRHNGVRGYYKGLLPNIMRVVPATALTFVVYEHTSHFLLGLRLPEEPQQEEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPI4</accession>
    <name>A0A3R7PPI4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDENN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002075">
        <property type="protein sequence ID" value="ROT73055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPI4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="UDENN" evidence="2">
        <location>
            <begin position="126"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="726" mass="78844" checksum="1E85EFBF0C47581F" modified="2019-04-10" version="1">MFYLSFILFSLLPLLIFFDLSSLLLSPFANLSPSPLCLSPPFFSFAHFSSSPNSPFLLFSLSTRSSSYSLPYPLLSFPSPYLSLLLSPFSSSLPPYPSPPLSFLPTHSFSSSSLILTNLSLFSSFFALYSSSSPPSSLPFSPFAYSSSYSFPPPPPPLSLPLPFLTHSFASSCPPSSSSFSTLYSFRLPFLLSLLPFVFLLLSPFALLSYSFPPHSLLRSSSPPLPPLSPFPLPFLLLPSSAPLLSLPSPLPHLLSLILPLLLSPSPFLPSLFISPLPPLSLRLLLSPPLLLHSLLRSSCLLLSLRSLLLLTPFPLLPSLSLPPSFPHSLLVHSSPLSFPLLPFSSLPFLSSSLPFVHSSSSLPSPLLFPPHSLLRPSFPPHLFPSLFFLLSPFPLPFLLSPFVHSPPLPPHSLLRSSCPPLSLRFTPPSLPSPFLSLSPFPLPFLLLSFVPLLLLSSPPLSSSLTPSPFLSSSLIPSPFLSFSLLRPLLPPLSLPPPHLLFLSLSPLPSFLFSLLPPLPFLLFSIRPFSSSLPFASSLLSPHSSPFLTLFPPLSHFSLSSPPPVSFASPLLSSFLLTHSLRSFLSSSSFVHPHFTPFPFPFFSLFPLPSFLSPFVLLPFLPPLPPLLTPRSLLSPSSPSSLFPSLFPFLFLLSPFVHSSPLSLPLPSLLPPLSPFPLLPSLPPLLPPSSLRPSSSSLPSPPLSSHSLLRSLLGRVTHPRRILQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUL1</accession>
    <name>A0A3R7PUL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001514">
        <property type="protein sequence ID" value="ROT77507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUL1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="678" mass="73885" checksum="DB51E21A85387011" modified="2019-04-10" version="1">MTFLFSLFLFFFVVSKFFSIMLFSPLPSPIFFSIFFFPFPFFLYIFSPISSSPISSLLLLPPHFLLLLLFNLLSFLLLLLGHLSSFSPTFLLHLHFFSSSSCIYSLHHYLPHLQHSNSFLFFLSHVSLVFSTTPTSSSSFSPTSPSPFPHLSLSCLPSPSFPPSSPPSTPSKFSLFPHFLHLLHHHLLPLPHPRPYTRPKFSSSLLPSPPPPPSPPLSPLLSPYTPSNIPRPPPPTTTSSPSSPPTHPSNSPSSLLPSSSTTISPLSLFSAPTPSNSPLPPSLHHHLPHPRPTPSKFSSSLLPPPSSTTISPSPLLSPYTPFNSPSFSPSPPPSTTTSPSPSSPPLHVQISLFPPSSTTISLSSPPTHPSNSPSSLLPPPPPPPSPPLPLLSLHPSNSHLLSFPHLLHHPSPSPHPAPYTVQILLFPLPPPHSPSSPPYTVQISSSLLPSTSSNLPSPSSQPYTLQFSLFSPSLHSPPHLSLSLIPAPTPSKFSLFPPSLHHHLPHPPYTVQILPHPRSLLPPPHHHLPLPSSPPLTPSNSPHPSFLHLLHHHLPLPHPQHVSHAPPLRLKVMGAELGLWDFETRGSERWRFSLGLAAHPSFLSQAQRRGQRGGLSGDEGPPSCLRCLKTFLNGSREATQAGDMSTPSLTRRVSAMYTRTARSIRDASERRSCRAHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1N1</accession>
    <name>A0A3R7Q1N1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023161</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000657">
        <property type="protein sequence ID" value="ROT83659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1N1"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1N1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="51172" checksum="6A606B7B23232982" modified="2019-04-10" version="1">MKKASRQRPPRRSQRKGGGGPESEGVRRRPNCLAPPSDVFFQGLSEERCSARGGGGEVSLLKGEFTLPFEARNEIEENGSGFERPRPPSSIPSLSLPSLYTLPSWHSWLSSVLLFPSPIALLSNHLLLLLFSIHVLTFLSTSSFRFFLFFSRLHLFHLPTYRPPSLSSLPSFLSFSYLLPPPHSLTPFSYPFSLPPPSENLSFPPPPSPGRNLPSLPPQSLLLHPFSIPVTLLPPRPSLRPRPFSSYPPFLGPFPFSLPSPTLSPAPPPPPSLPASDLPNPSPPPTPTPLPPPSFAPPKSLPPHPPDSLLDLPLTLPLPPPPPSPSLFHPARPSPLLPPGPLLFLLRHSLLDLPNPSPPPPLPFSSPLHPCDPSTAGTPSTPPLPAIASSTSLTFPLPTPTPSPPSPPPLRSLHPSSTPGTPPSPPSSAHSLPRPPLTPSPLPPTPFSFPSSTPAIPTPPPPPGPLPLPPPPPIASLDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q898</accession>
    <name>A0A3R7Q898_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ras guanine nucleotide exchange factor K</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_010569</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002340">
        <property type="protein sequence ID" value="ROT71131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q898"/>
    <dbReference type="STRING" id="6689.A0A3R7Q898"/>
    <dbReference type="OrthoDB" id="6382519at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF70">
        <property type="entry name" value="NK7.1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="49"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="2">
        <location>
            <begin position="51"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="16"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT71131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="167" mass="18402" checksum="6261B2F231DF10B0" modified="2019-04-10" version="1">MAAAAELTFASRAGVSGDVKGAAKRKKEGEEDAPAGTGTAADAEGSTDRKKKKARTTFTGRQIFELERQFEVKKYLSSSERAEMAKLLNVTETQSGSWSFSRPYFRRSCPARTPFYGQAKKALGGTKIGVTRRLMLTLKHLLKYTNRERSTEFNGLCASPELIPNNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9S0</accession>
    <name>A0A3R7Q9S0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004412">
        <property type="protein sequence ID" value="ROT61041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9S0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="744" mass="78454" checksum="DB64F59E6638138E" modified="2019-04-10" version="1">MAKREVFSGLVSAILFHTRSYHVTSDSCAYIWSQPALVSFRSLCLSVCRFTLVKPLASKAVTLTPVLSIYGLVCTLPAPPPSPPSFPVSPLPDSPTPPGTLLPTPSLPPFLFGSSLAPSFLFPLIPSSHSTPLILLTLSSSLPLPPPSLLSSFFSLLLSPPPLTLSLPLISTLLSFLSSPPLTPPFTPSSHPPLTPSSHPFLSPPPLTPPLTPPLTPSSLPLSPPFPPPPPLTPFSHPLPLTPSSHPLFSSLPLTPSSHTLLFPHLLLSPPPLTPSLTPSSHPFSHPLLSHPPLTSSHTLLSPILSHSPLTPFSHPLPNLPSHPLLSHSSSHPSSHSLLSHPLSLLTPLTPSSHPLLSPPPSPPSSPLLSPPPSPPSLTPPLTPLLSHLSPPSLTPPLTPLSPPPPPLLTPSLTLSHPLRLTPSSSPFLSPSLSSPPFSLLSPPLFLSLSPLLSPPSSTTPFSHPSSHTLSHPLLSPLLSPLPFSHPPLTLPLTPSSHTLLSHPPLPSSHTPLTPSLTPSLTPLLTPSSPPLLSPLPHPLLLSPLPLTPLLLTPLLSPPLTPSHSHPLSHTLSSHLPLLSHLLTHPSLTPPLTPSSHPLLLTPSFSPTFFSHPSSHTTPLPPFSHPLLLSPLPLTSLSHPPLLLSHPPPLTPSLTPSSHLSLTPLSHLLSPPLTPFSTPPSHPLLSHLLSPLSHPLSHPLLSPPPLTLLSPSCSNPKISSTSTFRLPLFHIHFSLIYTSYIHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9V6</accession>
    <name>A0A3R7Q9V6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_021149</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004352">
        <property type="protein sequence ID" value="ROT61112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9V6"/>
    <dbReference type="STRING" id="6689.A0A3R7Q9V6"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23165">
        <property type="entry name" value="Prefoldin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000005">
        <property type="entry name" value="Prefoldin subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016477">
        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="14848" checksum="214584B97AFC28A0" modified="2019-04-10" version="1">MATVAKDSDVHITYDDQQKINKFARCNARHGDVKEELKMKENELQNLQDAEDEIMIALDGDEKVPYMVGEVFIMKSQDEAQEAIAAQREVLQEEIAGLNTRAGELQETMTQLKGDLYGKFGNNINLEPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QB40</accession>
    <name>A0A3R7QB40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003742">
        <property type="protein sequence ID" value="ROT62278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QB40"/>
    <dbReference type="OrthoDB" id="297496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21698">
        <property type="entry name" value="PROTEIN (PUTATIVE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21698:SF4">
        <property type="entry name" value="PROTEIN (PUTATIVE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="603"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="844"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1205"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1525"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="929"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1608" mass="180843" checksum="A4A6110BBE23645B" modified="2019-04-10" version="1">MSVFLHHRHPRLSPPSSSRLSPPSSSRLSPPSSSRLSPPSSSPSFSTIVIPSFSTIVIPSFSTIVIPSFSTIVISVFLHHRHLRLSPPSSSRLSPHRHPVFLHHRHPVFSTIVIPSFSSIVIPVFLHHRHLRLSPPSSSPSFSTIVISVFLHHRHSVFLLHRHLRLSPPSSSPSFSTIVIPVFLHHRHPSFSSIVISVFLHHRHPVFLLHRHPRLSPPSSSPSFSTIVIPSFSPSSSRLSPIVIPSFSTIVIPSFSTIVISVFLHHRHPVFLHHRHPVFLHHRHPRLSPPSSSPSFSTIVIPSFSPSSSPSFSTIVIPSFSTIVIPSFSHRHPVFLHHRHPRLSPPSSSPSFSTIVIPSFSSIVIPSFSTIVIPSFSTIVIPSFSTIVISVFLHHRHPSFSTIVIPSFSSIVIPSFSTIVIPVFLHHRHLRLSPPSSSPSFSTIVISVFLHHRHPVFLHHRHLRLSPPSSSVFLHHRHFRFLLHRHLRLSPPSSFRLSPPSSSRLSPPSSSVFLHHRHPRLSPPSSSPSFSTIVISVFLHHRHLRLSPPSSSPSFSTIVPVFLLHRHPVFLHHRHPRLSPPSSSLSFSTIVISVFLLHRHPVFLHIVISVFLSIVIPSFSTIVISVFLHHRHLRLSPPSSSPSFSTIVISVFLHHRHPRLSPPSSSPSFSTIVIPSFSTIVIPSFSTIVISVFLHHRHPSFSTIVIRLSPPSSSPSFSTIVISVFLHHRHPRLSPPSSFPSFSTIVISVFLHHRHLRLSPPSSSRLSPPSSSPSFSTIVISSFSTIVISVFLLHRHPVFLHHRHLFSPPSSSPSFSTIVISVFLHHRHPVFLHHRHPPSFSTIVISSFSTIVISSFSTIVIPSFSTIVISVFLHHRHPVFLHHRHSVFLHHRHPVFLPIVISVFLHHRHLVFLHHRHPVFLHHRHLRLSPPSSSRLSPPSSFRLSPPSSSPSFSSIVISVFLHHRHLRLSPPSSSPSFSTIVISVFLHHRHLRLFPSASPSFSTIVISVFLHHLHFRLSPPSSSPSFSTIVISVFLHHRHSVFLHHRHLRLSHHRHLRLSHHRHLRLSPPSSSPSFSTIVISVFLHHRHLRLSPPSSSPSFSTIVISVFLHHRHLRLSHHRHPSFSTIVISVFLHHRHLRLSHHRHLRLSPPSSSPSFFTIVISVFLHHRHLRLSSPSSFPSFSSIVISVFLHHRHPRLSHHRHLLLSHIVISSFSTIVIPSFSIIVISVFLQHIHFSTMSFPSFSTIVISVFLHHRHLVFLTTSISPPSSSPSFSTIVISVFLHDHLRLSPLTSISSTIVISVFLHHRHLRLSPPSSSPSFSTIVISVFLHHRHLRLSPPSSSPSFSIIVISVSLHQHPFPPPSSFPSFSIIVIVFLHHRHLCLSLSSFSTNIHFLHYRYLRLSPPSSSPSFSIIVILFLHYCHLRLSPSSLSTNISFLHYRHLCLSPPSSPISSVIITISARRVTDDLWVITDDMKVLNESMWAASVRERLKLFERSLISAIKNDGWDGSEDLNTQQWTFAGALFYSIILITTIVTIGTTIISASITTNTITIITTTSTAMTITASTIAIITSTTCPPSLHYFFSTTTLTSSKTPRLCLSPTQSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBN0</accession>
    <name>A0A3R7QBN0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Crustacyanin subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_019457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003565">
        <property type="protein sequence ID" value="ROT62673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBN0"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018384146" evidence="3">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="5">
        <location>
            <begin position="48"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT62673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22512" checksum="EF720FA2C8DF5554" modified="2019-04-10" version="1">MKTSLLCLALVAVVAADRIPGFVVPGKCPAVDERMLYSQQKPNYQRYAGTWYEIALTNNPYQLIKQCVRNEYTFDGIKFNVRTTGTDATGNTITRNGQVLPNPFGEPHLSVDYEESWMAPYVILDTDYENFSCIYSCAGHNFGYYADFAFIFSRSPTLADRYYRRCESAFMNIGVDPSRFSKTAQGASCSYNTNYRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QF57</accession>
    <name>A0A3R7QF57_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative cadherin-23-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004532</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001600">
        <property type="protein sequence ID" value="ROT76858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QF57"/>
    <dbReference type="OrthoDB" id="6379298at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050174">
        <property type="entry name" value="Protocadherin/Cadherin-CA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24028:SF328">
        <property type="entry name" value="CADHERIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24028">
        <property type="entry name" value="CADHERIN-87A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="144"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="9">
        <location>
            <begin position="255"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="549" mass="62327" checksum="553BC47EC2C5C509" modified="2019-04-10" version="1" fragment="single">GELVGGEEPYKIRAQDGDQPGTVNTMITYYIEWVHKVGFQEDLGFFRAVNVNDTWSNTSYCQLMATQNLTWQRGTYEILLVAEDSGEPKMNGSTILNIEIQDSNDHTPEFWFEGCLKDKLQIKMEENYYQPGDRVLCATDQNALELEILVRDEDIGENRDFTCDIDYEKSTAVPVNGVDQLQDFELKRESDGCVLYVNSIIDRESGRRYNLSLHVKDKGTPPRESWEYLEVIVTNAFEAPPYFCLEGMCKETVYMKENDPDVTSMFLEAIDPDNIDSDPDDDGTYEDVFYNIVGGTTSFFELGGTNRMNNSIRLRNLPQGLDREDVPEYQLYIDVTNDPSVQPPISEQIPRNYTLYLTIIVQDENDNPPEFKKAITIASFTQNDEKGKKIAVIEANDVDLNETITYSLGKFAWNDTDGTVSTDEPFKIENGADLILNFKPTGLNSGYCTFRIYAHDKDNNTNFTTAKVYVITNAFQLPVSFNNGIREVSNKTEDIEDIFTSVYQYSCVVDSTTAETSDSGEAVEGQTIVYMHFIDETQNEPVPKNVIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGK9</accession>
    <name>A0A3R7QGK9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin carboxyl-terminal hydrolase 47 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002897">
        <property type="protein sequence ID" value="ROT66729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGK9"/>
    <dbReference type="STRING" id="6689.A0A3R7QGK9"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045578">
        <property type="entry name" value="USP47_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19718">
        <property type="entry name" value="USP47_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin carboxyl-terminal hydrolase 47 C-terminal" evidence="2">
        <location>
            <begin position="92"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="339" mass="38736" checksum="F349AE1B25222540" modified="2019-04-10" version="1">MPREPHTFPSNLESSDVSPKVQLSFAGTKLKVPRESTAVGVREGVLRDSYWPTLRPCAVRPPTMNSAKYSERTPTKAETMKEKRTQKYVDKISVLKPAKFLIDWVVCKGDTVASAKRAIIKEVNTRCNMTLTPETVRLRKKSWKNPQTIYLDAQKFEDDIPLYSNWELFLQIIEGPETKTASSDELALFTKRWKPSTYTTDAIAEVIISKPTVEGLREKLSEISGIEADDIEFAKGKGTFPFDMSVVDINSDLDWSIRSGPLDQRPLYILDDGAMVYYRDKKETPKEMTEEERRALVNSENRRLNRDLQYQCPSSSTTSSYSTLRSKEKGLKIYLNHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHK4</accession>
    <name>A0A3R7QHK4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zonadhesin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002772">
        <property type="protein sequence ID" value="ROT67705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHK4"/>
    <dbReference type="STRING" id="6689.A0A3R7QHK4"/>
    <dbReference type="OrthoDB" id="6378607at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018660051" description="Zonadhesin" evidence="1">
        <location>
            <begin position="31"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="44794" checksum="1F2046AF49541E98" modified="2019-04-10" version="1" fragment="single">PRTMKTRVPSTLPSLALLLLLHASCASALALPTADLETASSEVRAKRYFGRPDGINDYFEFGGVFDTNSNSFGNRDGYVGKPERNVLTVYETLTVTHTDYQQLELTKTLTETSISYVTHQNTEYITQTEPLPIYNTEYETEFRTEYVTETDYQEVPVFTTVFQTQYQTEFQIETEYQEVPVYSTLVTTVYHTKYRTEHTTTTETENYPIYTTYYTTFTETEYLPTYLTETHFDTQHVTRTATVTTTALDYVTTTAYVTTTTFQDVYVTQTHEVPSYFTETTVKQLVITQTESIPHYITTTEVREVMVTQTTTIPLYLTTTAISEVRLITTKPINNYLTTTEPLFMVSTVDRFITTTIPVYVTRTSTVQVQKSPQSYNTIDGRRWMWSASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMP2</accession>
    <name>A0A3R7QMP2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000609">
        <property type="protein sequence ID" value="ROT84012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMP2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="590" mass="62955" checksum="9CD9C3E2AFB7B8AC" modified="2019-04-10" version="1">MIYSPFSLTIIYSSLFTNHCLFIIAYTYFTHHSLTSLLSLPLPSPLHSLLAPSLLSFFAPSLPSPFPSLPLSLYPFSLLSSLPSPLSLPFPSLLPYPPSTSPLPLPSILSLFPCPSPSILTAVFPCALRLQFSPSSLAPRPPSPALPCRPRLILPLPDPFSLFSYTVGLPSILSLFPAPPLHSPLFAFALFCSPSSPPSPRSLLYPFLHSLLCLFLCPSRPFSMSVCPASLSALLFPSPSILPIFSPSPPFSPPLPLSPFLHSPSFLSLPSISPSSLTLPSISLLPPFFALLPFPLFLPLSPPFSPLLPCPSVSLPFPLLSLSPPLSPLPSILPSSPLPPFSLFPFLFSPPPVACTSAFPPFLSLFPCPPLFLPTPLSSPSASLAFPSSLFLLCRSPVLVLPLFLPSLLHPVPVLPLPSILPSSLFPFLLFSSTLFLYFPFLPFSSALPLLTLSPLPPFSPFSLCCPLPPSPPPLSPVPVLPFLHSVSLPLPFPLSVPILPSSFPLFFPLFPSPPLLSFLPPSSPPSSPLPLSSLSTLPSRCSCTSLPQFSPPLPLFLPPVPVLPLQRGPSALRIAPELSVKGGGELAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPW9</accession>
    <name>A0A3R7QPW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001922">
        <property type="protein sequence ID" value="ROT74209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPW9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="42661" checksum="BC3BDA229AB4A305" modified="2019-04-10" version="1">MVLPHLTPSLSPSPIHPSPSPSVHFLPFPSPIHPFHLPSLLPSIHLLLSFPHSPFPLSPLLPSPSSRSLPSTSPSPSPLPRDNTEPGRRMRAVSHDVDAVSHALQRKVAVSLCLGRCSARGGGGASIAAARVLGLRVDSQDEWRQRKILDIPSLPFPFFSTFIPTSSSPYSPYLLLPNSPIPLPFFSPLILPSHHLLSLLSPCLLLFSFSSPSSTPVHLPSFYLFLSSSSSAPLPSPLRCFSFPLCFSLSLLLLSLSSFLFLSSPNLPHPLPHLRLPIHFYSFLASPTDYAFLPPPSSSPNLPTVFPSSPPSPLPIQISFTVFSAFPPPFLSKSPPPSPRPICAPCSLTGAENDMRKSLFVEDIFVGLFPSSGRPWIQARFLWRKKREGDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRF9</accession>
    <name>A0A3R7QRF9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimers with GPN1 or GPN3. Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRF9"/>
    <dbReference type="STRING" id="6689.A0A3R7QRF9"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="35269" checksum="5CC191CD8771CF09" modified="2019-04-10" version="1">MVVQFGQVVLGPPGSGKTTYCKAMASLLRGLGRKVSIINLDPANDVLPYEAAVDVSELIQVEEVMATKKVGPNGALVFCMEMLEANLPWLLNKIQALEGHYLIFDFPGQAELYAHHTMVRNILRELDKAEIRLCAVYLVDSHYANDPGKYVSAVLLTLNSMLMMELPTVNILSKVDSVEKYGSLDMGLEFYTEVMDLEYLLEYLGDAPVTRKYTKLNKAMADVISDYSLVTFIPLSADSRSTLLAAMKAIDKANGYIYGSGEERNIQRLLSCAVGAEFEHERLGNVRDEFMRGNSEEEDDEDEEIIKMIATQNQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIR4</accession>
    <name>A0A3R7SIR4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Facilitated trehalose transporter Tret1-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_019407</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003559">
        <property type="protein sequence ID" value="ROT62739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SIR4"/>
    <dbReference type="STRING" id="6689.A0A3R7SIR4"/>
    <dbReference type="OrthoDB" id="6360451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="91"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT62739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="546" mass="58581" checksum="468CD0EB30E4C6A8" modified="2019-04-10" version="1">MGKCGLESPVMGTKASGDDIVQKGIDNVAYEQTDTHYGDESSCRYIQGEFSLDGENKPDVRKDSPHREQGTGQDGKAAGDKNEGQRVKYTWQVVATLVMSLIHLSVGTIYGYPGVMLPELTDPSTTDIFLSTNEAALFSSLSNLGAAFGAILGGVFLVRLGQRTTLLIGVPLTAAAWLGLAFAGVPWLIHAMRCVLGITTGFIAPATGIYILEISHKKSRGVFYGVLTTVRQMGFLCVYALGSSDLGWRNVSLVCAGIALVPFLALFFLPNAPRWLVTQNRVEEARKSLAFFRGKDYDSTSELKAITDQVGQHAEQNKSFITQVKMMMEPATLRTLALLVVISVLSTLSGYIIVTTYTVTILQSTQGDLDAYISTIIIGAVRVGGTLVHLAVIDRFGRKPLLVASFALGTLCVAGLGGYFYIQNTTGDASYLGWLPLTCMVVLIFCMGIGQPVVSIVQGELLPTTVRAAGVSLIMILLFLAGFVLIQTYPLLSGALGEHGAFWLYSGASLALVLVGGLRLPETRGRSLEEISGRRERRASLSPSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SKM1</accession>
    <name>A0A3R7SKM1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003176">
        <property type="protein sequence ID" value="ROT64843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SKM1"/>
    <dbReference type="OrthoDB" id="6618089at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="292"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="456" mass="50698" checksum="F8F77FEE16CECD8E" modified="2019-04-10" version="1">MINAFIDTGSEATLLKHSAQTLIAPSRTSEPRRRLQGASGASLAITGERDVILQINDKNIVTHRVCIVDGVDFPGDILIGIDLLKRLDFRLGYDSRTNNSYLRLRGKAFTVRYVNKDSLELTAVVMKMKGISVPVPPARAAIRRSVSCPPESGRFPVRVPDALIGKQLLVEGLGYSVILPREVIKPSSKEAVVWVVNPTLNPVKLRNGTHLVELHEVEEMCDTPEAPGNVASIADTPVAAVPTSALEKISLQHLSDHRDKFAIGEVPDIVHEIPTQEKHPLCQRHRRRCSLLRALDVARKAAQEASRKARQEYAAYHNRNLRPPWSLEAGSLVLYKIKTTQTGPDRALGPRWQGPAKVVKKLGPVNYVVQDLSPPFSERNCHANQLRPFKLEEELTFPDASPYHDPDYVDPWLPDDAEPDHSNTSTSCGLSSETDVARTTNHTWNYRSAQDHRFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLP4</accession>
    <name>A0A3R7SLP4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Actin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_015890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLP4"/>
    <dbReference type="STRING" id="6689.A0A3R7SLP4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000205">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT66122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="20084" checksum="D6A7446740AB470C" modified="2019-04-10" version="1">MTERGYSFTTTAEREIVRDIKEKLCYIALDFESEMNVAAASSSIDKSYELPDGQVITIGNERFRCAEALFQPSFLGMESAGVQETVYSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITTLAPSTIKIKIVAPLSVNTPSGSVVPSWPLSPPSSPCGSPRKSTRNLVPVSSTANVSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SPK6</accession>
    <name>A0A3R7SPK6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002540">
        <property type="protein sequence ID" value="ROT69651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SPK6"/>
    <dbReference type="OrthoDB" id="6376179at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="44241" checksum="DF914B3670ECFE9F" modified="2019-04-10" version="1">MDEIKKDEKTSQAKVMEGTEESLKRLEKKYEDVLEKYKEYRRDGEEKKQEKEFLQTCLPSRLPRMEVRADEQSSKILAMKEKVCLLEGKTQAQSSTLALAKKRLEEIKEAKNELQKKMGVIETRMGSRRTKMAMAAKAVEKMKPLADVLERDVTHFEEIYTKNEEEYVKVREKNRKVVIYQTEGNKRSLGNEELEKTIQLLTRRSQEQKEVCKELKSKEKAAMEKIDDCYQKTNEEGELIAEINTTYERKWTKVHESLGHCNRLIEASNLEIQELKDDTPVVTADLPVKQKQEAVNQEQDELVIVGSVELKRKEVDELPPIVEDCTVVLDEITLDDCPLYIDEAAMQDSPMYVEDTAWHDSTILTEDIIDITEESPTNSPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQG7</accession>
    <name>A0A3R7SQG7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010974</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002392">
        <property type="protein sequence ID" value="ROT70736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQG7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1280" mass="137982" checksum="BA2BCC5C5DEC04E3" modified="2019-04-10" version="1">MVSAGLSCPSISHLPPLPPIFPVTSFPRVCSFLHPFFHYHASLLLPLFLNYNHFLSASSILLPSPRLPFSSLFLPALSLRFFSFSLFCLPPPSLSPLSSHFPPVFPPNIFPFLSFLPPPHYPSPFPRCSLPPPSPAAQYPPPSPRCSVPTPHPSCSLPTPLPLLLITQPHSPLPPLLITHPPSPAAHYHTPSPAAHYTPSRCSLPTPFPAAHYPPLPPAPLLSTHPPSPLLSTHPFPAAHYPPPFPRCSLPTPFPAAHYPHPFPCCHSFPRCSLPTPFPAAHYHPLPRCSLPTPLPLLLITHPPSPCSLPPPPAAQYPPPSPAAQYHPHPSCSLPTPSPAAHYPPLPRLLIPPLLIYPPFPRCFITHPLPTAAHYPPPFAAAAHYPPPFPAAQYPPPSPAALIYPPPSPAAHYPSPFPRCSLRCSPTLPTAAHYPPPFPRWLMYPPPFPPAQIYPPPFPAAHYPPLPRCSLHPLPRSAHYAIPLSLAAHVPTPRFLPAAHNRNPLPLLAQVTATPLTRRCSVPHPRHPASCSLAHRPFPAAAVSHRPLPSLLITHRPSPAAHTQTPPSPAAQYPPPFPPLLITHAPLPPLAALPTAPSPAAHPPSLLLSNRTPFPPDWLLITHRRFPCLLIYRSPLRPPAAAVNPSAIPRRCSLPTPTSAAAAAMYPTPLPPCSLPPPSFPGCSVPTLLSPLLITQAPSSAAQVPHPPSARCCSTHPASQLLIYHTLPLLLHYPPPLPLRAASLTHTAFPRCSLPHLPFRRWLITPLPLPRCSLTHTPSLLSLPTPLPPLLINPAPFPRCSLPTPSPRCSVPPPFQSAASITHPFPRCLITTPFHRCSLPTPFPAAHYPAPFPRCSSTHSPIPSCSFPLPLPLLLSNPPPCPPLLINPPLPPAAHYPPPFPAAQYHPLPPPAHYPPPFPRCSLPTPLPLLLSTHTPSLAAHYPSPLPTAAAITHPPSPAAQYPPPFRPLLHYHPLPLLLISPPPFPCCSVPRHTLPPLLSTTHPSLLLSTHPPSPMLSTHPPSPAAHYPPPFPCCSLPPPLPPLLITHPFPAAHTHPLPRCSLPTPLPPLLITHPFPRCSFTHTQPPSPAAHTHPLPPLLITHPLPRCSLPTTRHLPHPPVPATQYPPPFPPCSLPHPPSPCAHTHPLSPAAHYPTPLSPAAHYPNPLPLPASYPPPFPRCAPLPTPFPRCSIHPPPFPRCSVTHPPFPRCSLPTPLPPLLHYPPPPPATPSTHPPFPRLITHPPFPPLLHYPPPSPAASLPTPLPPLLITQPPSPAAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRJ2</accession>
    <name>A0A3R7SRJ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_009733</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002229">
        <property type="protein sequence ID" value="ROT71917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SRJ2"/>
    <dbReference type="STRING" id="6689.A0A3R7SRJ2"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000679">
        <property type="entry name" value="Homeobox protein aristaless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050649">
        <property type="entry name" value="Paired_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329:SF543">
        <property type="entry name" value="FI01017P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329">
        <property type="entry name" value="HOMEOBOX PROTEIN ARISTALESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018639756" description="Homeobox domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="9">
        <location>
            <begin position="255"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="257"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT71917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="393" mass="42432" checksum="208D14DE29386AA6" modified="2019-04-10" version="1">MNLFLSFILHSTLFYSSLSSIPPLSPHLPFPHHPTSLLPFPHPPIPSFPTLHFPSVPPILPTLPPPLSPSPTPAPPQQFRNPPPNFFSPLPPSLHPTPPHPLPKPPPLNPSPNSPSNPLPLLSPPLRPPPPHLLSPHLPHFFSTPPPSYLPPLHAPTTVPPSNPPPQISSPSSSHLPRPPHPFPSLSPPLHPPQQFRQVTPPPILLPTFPPPTSHLLHHHPPSPTLTAPPLHRPHNSSANLSSPLHAPTTVPPKFERTHYPDVFARERLAAKIGLPEARIQVWFSNRRAKWRREEKLRNQRRAAEGVAPSSPTRIVNNSFTPTPMYTPLPPPPMSVADTYGSMTGPGGGFGMASSVGVAATSPNCLGSQQPPTGVSSLPACPFPSPCQARTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STV2</accession>
    <name>A0A3R7STV2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein-L-isoaspartate O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001840">
        <property type="protein sequence ID" value="ROT74854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STV2"/>
    <dbReference type="STRING" id="6689.A0A3R7STV2"/>
    <dbReference type="OrthoDB" id="6366364at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051435">
        <property type="entry name" value="RING_finger_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791:SF6">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="201" mass="22908" checksum="4C3807B9036CD09C" modified="2019-04-10" version="1" fragment="single">ENFYSSGQHYENSSENQAPSGITCAVCRSTYNAHDRRPLIFSSCGHTFCEECLRTENRKSVFRCPSCRQDRDQFWTLKPNFALLDLLEAKGLRMDDDDLLSLALHMSAQEAENKEYRRQVAALLAREPAGAGDVPGAEGGWQEEAEGRPGKEEAYCHEELEGHSRKKLRLEKEKAEREENIWLEEERTTVGHGYVIISPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYH0</accession>
    <name>A0A3R7SYH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Beta-1,4-N-acetylgalactosaminyltransferase bre-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_025458</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000986">
        <property type="protein sequence ID" value="ROT81379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYH0"/>
    <dbReference type="STRING" id="6689.A0A3R7SYH0"/>
    <dbReference type="OrthoDB" id="10038994at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008378">
        <property type="term" value="F:galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033842">
        <property type="term" value="F:N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00899">
        <property type="entry name" value="b4GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003859">
        <property type="entry name" value="Galactosyl_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027995">
        <property type="entry name" value="Galactosyl_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300">
        <property type="entry name" value="BETA-1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19300:SF57">
        <property type="entry name" value="BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13733">
        <property type="entry name" value="Glyco_transf_7N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02050">
        <property type="entry name" value="B14GALTRFASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Galactosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="355"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Galactosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="491"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="260"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT81379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="618" mass="70801" checksum="17FCA0210DED918D" modified="2019-04-10" version="1">MSSKHQFYRLESDYYSHEESRTHSGRNHRTYQEFNFDNYNQLPTSEDSQDRGRDRKEIFYLPLAGKEPHRGGQGIQDKKAWKKDCRNQRQIKEYPQQELYCQRSISSCEQKLSAGQSFSYLGGRMYPPPSDGGLGRFIPSGGSGGSMWSGRVPVCRPRFWKLFLLVILLLMMAQFSLNILFYRNYDSLFYVNVTSAETLATFESKVRWVSSKLPWLHSTTGKPPVVAPLHHPGVMPSSSSHVVGDTSISGKLEEKVLFSKDNENESQVNKDEKKVVDKSVNSANNSKLSSVTSKSKELSVKAPSKVVNGSDGKADAKLLKIPQINKELGKLPNVSTSRVSGEQKRVLLSKEKALCPPVPPKLVGSVKIYRSVPTLEEQEKSRPELEPGGRFRPAECRARHRVAIIIPYRDRVQHLAMFIYHIHPILQRQQIDYAIYVVEQAGSGKFNRAMLMNVGALEALKQYPYDCFIFHDVDLLPEDDRNLYTCPEQPRHMSIAIDSMGYKLPYNDIFGGVSAMTADQFRTVNGFSNKFWGWGGEDDDMSNRIKFHGFFISRYPANIGRYTMLSHKKDEPNPRRYHYLYDGKKRFKSDGLNSVKYRTLDLQLRRLYTWVYVDLYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0H7</accession>
    <name>A0A3R7T0H7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_022673</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000589">
        <property type="protein sequence ID" value="ROT84142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0H7"/>
    <dbReference type="STRING" id="6689.A0A3R7T0H7"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22466">
        <property type="entry name" value="KH-I_HOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000055">
        <property type="entry name" value="protein quaking isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF125">
        <property type="entry name" value="KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="7">
        <location>
            <begin position="138"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT84142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="43712" checksum="673D083CE98BCBB2" modified="2019-04-10" version="1">MWRGRVARAGMCVPGGGVRALGFPHTPRRARRAHSPWGGDNSPVGIVEQTNFDSFWPAQPRSLAPYRLVETRCPAPSPRPLFTRPARYSFSCGDFSVLSRVSLLYCGEEINKVRANLFHINGGAKEPLSLPDPVGASVTLSDKVYVPVKEHPEFNFVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEELHVLITVEDTENRAKLKIQRAIEEIRKLLVPSADGEDELKKRQLMELAIINGTYRDSSSKNAEFEALGHLAGEAPRLITPGMTLPSPLRTTTPLGGPPLIMPARIHVPTSNALINGTGNAGMPPPLIAASDASASLLYAAPYAAAAEYAANYAALTSPLLTEYPPDAAGVAAKQRRHLGQAREHPYQRTGTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T151</accession>
    <name>A0A3R7T151_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative chaoptin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_021560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000454">
        <property type="protein sequence ID" value="ROT85019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T151"/>
    <dbReference type="STRING" id="6689.A0A3R7T151"/>
    <dbReference type="OrthoDB" id="5789657at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007409">
        <property type="term" value="P:axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051965">
        <property type="term" value="P:positive regulation of synapse assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45773:SF10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45773">
        <property type="entry name" value="SLIT AND NTRK-LIKE PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="240" mass="27693" checksum="F1F46F6D0914ED50" modified="2019-04-10" version="1">MSNNAIKNFGRNPFARNTLLGWLNLSNNKLGKVESNSFRSMRFLRRLFLSDNEINTIQRESCGMRLHLAQNSVWLATARFKSWDDVVCAAPQHLQGRALPFITEEELRCTDNRRSFEEYQVNPDVRFRLKDEENRDVLEKLDISWYVTTREDVGGFKVSVYNTTSGKEVSSKSLGYTARRQRFPEVPRGRYRVCVGGLTSAEESRALQPAQCHGFFVSHARVPLPTPLLLIFLIILMLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGP9</accession>
    <name>A0A423SGP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GST-N-Metaxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_018706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003442">
        <property type="protein sequence ID" value="ROT63430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGP9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like fold" evidence="4">
        <location>
            <begin position="237"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="3">
        <location>
            <begin position="410"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT63430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="54832" checksum="CED7209901E909D2" modified="2019-05-08" version="1">MYGKEDGVTGLYKAQATRSYTTPRQGTASLTTLENQILKMASIRFLLAVALLVAAQVSLAAAAPQRWYSYSGGFDRDDRFDNDRYDNDGFDRDDGFGNRGFNGNSGYYNPGFNSNAGFYNRGFNRYNQNGGFYNQGFQRSSGSFNRGFDRDDSFEGRNMLQNVQDVWLPARFAGRALRLLWGKNKPVTITVVVVVGVMKIRSYMKKQERRRRWNNAGKDVVVLHIPPRGFFCPSLSPFVVKLETYVRMAEIPHVIDHEEPLGPKGKTPWITLNGEDVGDSQMIIEKLAAKFGKEFDAHLSQEEKAVAHSLRIMVDEYFVWCLGVYRYGQEQGRHFLLNASIPWFYRPILPMYFKRYVEAAKTQGIGRHSYRDVEEMGRKSLQSLSAWLGKLFFALSVFVEVIHILSVSSEKPFMMGANPTELDCTVFGMLAFDVFCPPLSPFKRMLEKDYRNLHAYCHRMKEKFWPDWDKCLDPNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHD3</accession>
    <name>A0A423SHD3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Caspase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003420">
        <property type="protein sequence ID" value="ROT63569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHD3"/>
    <dbReference type="STRING" id="6689.A0A423SHD3"/>
    <dbReference type="OrthoDB" id="6116485at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043525">
        <property type="term" value="P:positive regulation of neuron apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033139">
        <property type="entry name" value="Caspase_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016129">
        <property type="entry name" value="Caspase_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10454:SF232">
        <property type="entry name" value="AT03047P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10454">
        <property type="entry name" value="CASPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00376">
        <property type="entry name" value="IL1BCENZYME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01122">
        <property type="entry name" value="CASPASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01121">
        <property type="entry name" value="CASPASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Caspase family p20" evidence="7">
        <location>
            <begin position="38"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="258" mass="30039" checksum="1C944DACCC362F7A" modified="2019-05-08" version="1">MANKSNERAAVVTENQSRHSASKSLDRDDLVYNMSHKERGHALIFAYEEFCAYGPGRRDYARHDVDICTEAFRKLKFEVRTYWNLKRDMLLREIMKESRGDHRNRDCLVVVLMTHGGTNGKGEEVVWTYDFEIRTSELWKNFKREKCPSLAGKPKLFFIQACRGENVDKGVRLRPVGFRVQSDDFSQEDEHTSVLDADMLIMWASYPDVYTRMYAFVSPFNYNGSVFLHFLSKVLIEDGDHQDLAAMLLRVTREVADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJD2</accession>
    <name>A0A423SJD2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative serine proteinase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017701</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003260">
        <property type="protein sequence ID" value="ROT64357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJD2"/>
    <dbReference type="STRING" id="6689.A0A423SJD2"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF278">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR 88EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Serpin" evidence="4">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="20546" checksum="C103F29F94913A81" modified="2019-05-08" version="1">MNHVIITNFKYVQLRFSGLEGVSRPGAGDALQGRQRVHGGAPPAMWGIQDGDWLVQRLKPKVLVSELKAMPSVSLRVKFPKFSVESTLGDELISTLQKMGIRDLFSSTADLTNFTPVRGLLVNGAIHKALIEVDEEGAEAAAATAFVLNRSRSMPPKTTFTCNRPFVFFIQDNEANNILFIGVYRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJZ4</accession>
    <name>A0A423SJZ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Neurotransmitter-gated ion-channel ligand-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003247">
        <property type="protein sequence ID" value="ROT64479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJZ4"/>
    <dbReference type="OrthoDB" id="6351594at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="64321" checksum="60F967532573B3F0" modified="2019-05-08" version="1">MATFGYFADASGVPIYGLHTESPPQQGMTWLQKDLAIQEPSEHITVCLHMRLHFVYTDPAIVLYIDGTFFAVVYEGKFALFNARYFWSSDTAPSVRAWSHLCYVFGAEPGVAVGGRYVPGRRQGDLGDPMPIVAPRNLTLGTPLGASDPLSSSPVGGFFTVPRVYTRKLTEDEMRTLAECGEGPYGDQVAGSWQVRWTQWEGPESAHTVDLGTVPDTLVSPLNYEAYEFHNLTPSALFGNVPSEAMCSPQPRSKYMLVRADKVSYPPAERLCSVYGGRLPETFDEPMVMNTLPDLMLFTWIKSNGNKTCRSLGIQARKDVALDMSIGCGHTSRQLLCEVPWSSYVELRHSGPAGYDDRFFLLTRGTRPVFLSQNGRQIVGDGASGTELKLLDSDGEVLATARTARRFHPMGRHVWRDAATNATRTMVLSACGQTEFTCDDGWCVPLSTRCDGANDCGDDSDEACSLLLPLPPTYRADRPPLPRTPLSLLVRLVRVHDVDVANNLLTAWLQLETRWRDERVLFSQLSNEAMDNILPQPDKVWSPMYDLDNAVFQDKVAYLHAKFSSRKRQRGTVLGIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STS0</accession>
    <name>A0A423STS0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002786">
        <property type="protein sequence ID" value="ROT67624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STS0"/>
    <dbReference type="OrthoDB" id="6381127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="166"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="324" mass="37319" checksum="384B65A97EC68417" modified="2019-05-08" version="1">MAVVANNLGGKTRQDEQEDDEEDGHPWSIDEMIREQNQDPLYSPVIKYLQTKNLLDKRKVDPNLVVEDYFLDQGLLYKQVRTPNSARDIKEVLCVPRTLVPKALALVHLAPLGGHGAEERTKFRARQNFTWRGMDRDIAEYCRKCITCAKFKGRAHPLTPLRRYPVPLEPFQMVSMDLMGPFPLTERGNQYILVIVDFLTRFAVVRALPNKYAETVAEAVSEVFADLGIPQTVLTDQGREFRNEILKEMAKHMQFQHHKITAYHPASNGLCERTNQQVLNILRGMVDGKDQYWDLYLKDTQMALNSAYHKAIGDTPYYAMYNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUQ3</accession>
    <name>A0A423SUQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">JHE-like carboxylesterase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002738">
        <property type="protein sequence ID" value="ROT67908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUQ3"/>
    <dbReference type="STRING" id="6689.A0A423SUQ3"/>
    <dbReference type="OrthoDB" id="6767738at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="216"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="582"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="619" mass="67521" checksum="0B1874BE9423B613" modified="2019-05-08" version="1">MCRGQERRARDGSEVAALPCVPQLSMRDYDGENSWWPVASEELLSLPVSITVQQGLRLEFDIVRTELGRIIHAYHGYGSILAPSSVLVKGEACNFTLNSGHSSRARPPTQYINKPLRSLHRITYTNQPKNNHPFPTPTPKVFPSDMPRDGVAPRGGLPRGGVRGAVPPCPCSRGTSCWSQSSAVRAGTLGQVKIPLHGRRGAAGEPRPQGPDAGPRWVKENIRALGGDPFRVTLFGQGAGAAAAHLQVLSPQAAGLFSRVILQSGNALSPWALRCDHRKNAAVVGAAFGCAGVDSSSPADLNSTALLDCLRELPFEQLAVIPSVFVTWLNAPQVMTPRVDGSFLPAHPALLLRDGRFNRVSLISGVNQEGALPALATLETPFLKKALTERFPEVGPVILNVQEEKNAVLLARQAFSAYLPQYRVNEDTVGDFAKLLGDEAFRIPHREVVRLHSMAGGLVFAYELKHRGLQSLTDIFNTSAGDSWVSNGDDLQYLFNGTTFPPLKNLDDRRLSDLMVIMWTNFAATRYPTPDSSLGFWWTPVGFSSPMHYLCLTPTPTMAWDGRSPMYEFWTSLPTFQNRVLHPSTSLARPGDSDARCPRSDRTPGQPVPFPATGSDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SV48</accession>
    <name>A0A423SV48_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative obg-like ATPase 1 isoform X5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_013801</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002721">
        <property type="protein sequence ID" value="ROT68086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SV48"/>
    <dbReference type="STRING" id="6689.A0A423SV48"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000029">
        <property type="entry name" value="Obg-like ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="221"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT68086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="34967" checksum="8D9B8077332AEB5C" modified="2019-05-08" version="1">MSTGKGDKIVRNLAVSVKVPVPDARYDYLCEFHKPASKVPAFLNVTDIAGLVKGAAEGQGLGNAFLSHIKACDALFHLTRTSSTSKAAYDKLEKLAVRGRRQKAQARVRHHLQSRSCSRRTRARALSIEVLNKHLLISSKPMIYLVNLSEKDYIRRKNKWLVKIKEWIDANDPGAICIPFSGVFELKLAEMEPEERANYLKENNLTSALDKIILQGYKALQLQYFFTAGPDEVKAWTIQKGTKAPQAAGKIHTDFERGFVMAEVMKFDDFKEEGSEAGAKAAGKYHQRGRTYVVEDGDIIFFKFNTGGLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVY3</accession>
    <name>A0A423SVY3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002680">
        <property type="protein sequence ID" value="ROT68367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVY3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="41994" checksum="CF73F234E10433F5" modified="2019-05-08" version="1">MKIHIHSTPAPSPLFGSPSPHPPPSPSSSSPLLFVPRSSIPPFLLLGAPPSSSPGTSILPVPRSPFFTPPLLLLHLHPPCSRSPFFTPPPPLGAPPSPMLPVPLLHPPPPPPPPPRHLHPPMLPGHLPSSLPPPLLHPPPPPPPRGTSILLLPGTSIGAPPSSHAPGPPSSPPPFLLLGAPPSSHAPAPLLHPPPPPPRGTSILPAPGLFFTPPPLLLGAPPSSLPRSPSSPPPLLLLGAPPSSHAPGAPPSSHFFTPLLLLLKAPPSSLPRSLLLHPPPPPPPRGTSILPCSRAPLFTLPPPPSSPPSCSRPTLTLPPLPSFPSSPSSCSRAHPLYTSPPSPPFLLPPPLPAHSLHFPPPLLPPPPPPAPGPPSLHSPLPSFPSPLPLPLSTRHFWKEGSLEILCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SW81</accession>
    <name>A0A423SW81_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002663">
        <property type="protein sequence ID" value="ROT68469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SW81"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="48026" checksum="215C600FF4268A1E" modified="2019-05-08" version="1">MRAKRARELAQCQHLSSCRLEVALYLSGREKLQRSISRRESKLLQRPLSPRGARAQLQRLSLGAREHSCSALYLSRGRESTAAAPSISRGAEEHSCSALYLSGRESTAAAPIYLSGRESSALYLSGARAQLQRPLSSGRESTAAAPSISRGARAQQRPAAQLQRLYLSGRESTAAAPSISRARRAQLQRPLSLGAREHSCSALYLSGRESTAAAPPLSLGRESTAAAPSISRGARAQLQRPLSLGAREHSCSALYLSGRESTAAAPLSLGARTAAAPSISRGRESTAAAPSISRGARAQLQRPLSLGRESTAAAPSISRGERAQLQRLYLSGRESTGSISRGARAQLYLSGARAQLRPSISRGARAQLSALYLSGRESTAAARERCSALYLSGRESTAAYLSGRESTAATPSISRGASDRDVDAKGLLLRPERVYANCEIPAEYSMKDERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0W3</accession>
    <name>A0A423T0W3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002464">
        <property type="protein sequence ID" value="ROT70126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0W3"/>
    <dbReference type="OrthoDB" id="6355263at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="49858" checksum="5589D40800DACB76" modified="2019-05-08" version="1">MAEGETSDDLQTLIRPDDLEGITEESTGSAATHSAPSLLHDPPPAWQLPVQCVLLVLVTTALVIILPVYLESVNVVGDAYSALIFAAIFTALPVVLFVQIRYSYFCQFMRLGPSSPSAILKTGMFHGISSLMIVYALDRKRVVCHAQEPLMGLIVMYMIIIYFFYKGPELSSPKMFSLCGVLGGLFLAMDFQLNNLYRCHGRSRKNPEDDGGPWSAQAHALWTIVYAAALFLFTLSWLLLEREVITKKSGTGGLSMVSTVSGGMSAPGSDAEALISSRGAVVSTPMQSSLDAKWGIHLVWFTLASLFTIMMLFWTDFFTALGKAGSPQEFVKLTSGGLRCHFHWGGECGPTALYGWLFVALHLAFLVLLGRVLAASHSIIYALSVTSVALPVQALWWSMFRIGGPLGMEWYPQESGEVIFSLLGLPIMIACLCYWSHVEKREKQRSNNFPLTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2H8</accession>
    <name>A0A423T2H8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002398">
        <property type="protein sequence ID" value="ROT70697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2H8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="58854" checksum="B6F6ADDACB999572" modified="2019-05-08" version="1">MNRTPGYPPPGHPPRISPWHTQVSSPASPSLFFFSSIVFLSHSCFSLPPLSSVSLPFPLLILFPTSALSHSLSLFHSFPSPPSLPLVSLSPSLSLSPLISLSPLSPSLPLISLSPLSPLSFSLPLIFALPLSLFYSSHSPPLSTLFLSFTLPLISLSPSPLPRALCFSPLTLVSHSSTSPIHFYKAKLFRNGRNLFFPLLFFSLSLSPFLSSLPLVSYQNSSPTFPRIGPREHGLRLSTLLPPSVLCPPRSLRLFYLSLSLRAVSALSRPLSLSLSPSLSSLLISSPVSLSPTLGCSGEPVGGPALSLFTESRIRPPPLPLSLPVPPLSLCPVPGRALSLSPLRRCGARACVVSSSCLRALSSLPSCVVSLSPSPVCSLFSCPSPLSLSRLHPLSLSPPPLSLPSPGEREGERESLPACQLASRSPSLHQTARFVSSGRPCDPPPLLRTVFFLPPPPSPSPVTPTLPNPPSISPLPHQLSPPARPSPSPSPIPSFPSFITSLRPPLPPPPSSPILLPIISLPPPPPLLPHLPPFSQVHPRRNRDFHAHSRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4C4</accession>
    <name>A0A423T4C4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002324">
        <property type="protein sequence ID" value="ROT71235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4C4"/>
    <dbReference type="OrthoDB" id="6366218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="221" mass="23343" checksum="5DD7524283837FD0" modified="2019-05-08" version="1">MTRERFLWGSPGVARYLCPLGASRCARGGAGGGAGPRATSPSPSTTTPPGAASSSYGAATTPHAGPFTPLGKGNISELTVTARGTEVTPDATSHLSWQRRAVLVGDQEVSFRTVTLPPETPQSRRSSRRSTTPSRHSLRLSLSDELPEDLTFDVFESSEEEFPVDAHHLSDDNEDVAGAGAGAASKDVGQRDRLPSIRRVGSRQMLVFLTDGNTIGDVSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T652</accession>
    <name>A0A423T652_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T652"/>
    <dbReference type="STRING" id="6689.A0A423T652"/>
    <dbReference type="OrthoDB" id="6358447at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="9"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="51324" checksum="3DC1D1AAB5388CCE" modified="2019-05-08" version="1">MGKWSPEYKQLSSAVGVSMVGVVLGVVIAFPALALDAWRLEGDITLSEVEAGWFVSVAQTVSVAGSIAGGYLNDVLGPRRLLLAVLPLLASTWPVLLGCVHNLPLLLTVRVLQGLLCSAATASVYIYPCEVTEARRRGAVGVLPDAAFSLGFMLTYFLAAILHWSTVVAILPLFFLPCVVTVFLVPESPSWLLQRGRVEEARAILQQLRAPDVNVEKELLGMGPLGECGEASVARQPRLLLPILASIFLMVLKEATGQIVVVLFVVHIFRKVDVGILPHVSSMLVGSARLVANVACSLLVGRLPRRTLLISASLTASVTIAVLGDYFFRQDSQVWPDWVPLACLSVFVVAYGAGIGPVTCLMATELLPGAVRGLGSGLAGSALNASQFTLTFAATQAGSGFYICLWSYAAGSACLAAFALLLPETRNKSLRQIEEYWAEVSENITGKRWCPCARRGAPDDCEANAKSNTRNNDTELVRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6R5</accession>
    <name>A0A423T6R5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative chromatin-remodeling complex ATPase chain Iswi</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002194">
        <property type="protein sequence ID" value="ROT72190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6R5"/>
    <dbReference type="STRING" id="6689.A0A423T6R5"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="17058" checksum="84AF419DDA165C53" modified="2019-05-08" version="1">MSDAEDVVEPMDVEENSNESSSAETTSSSKAGGEYENKMEMDRSKRFDYLLKQTEIFSHFMAGSRDKTPSSPLKCKPGRPKKAENRKPSVSGDLAKKFTSSAADGRPRGMGAEWAREYQPPSRHSPCGLTGPRPTTPGPACAMGCLPPNELFAYCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T741</accession>
    <name>A0A423T741_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009339</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002184">
        <property type="protein sequence ID" value="ROT72267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T741"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="495"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="529"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="607"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="725" mass="80541" checksum="0BEC4D75DF97B98B" modified="2019-05-08" version="1">MAWSSVTGYPRRDSEAATPAGQGMVLCRRVRFLFDNKTLEPCSESDNTNSHKFMEVAKDLKKVHMTGVLNQQGVVAAVLSIPPLSLLPVFSSLFSLFLSSLFSILSLPSLFLILQSSLLFHLPLSLPPSFPLPPIIQLFAPPSSFPSPIISFFHPLFFASLASSPNTLLRIEGRFHNLSPPPPPRAPTSMPSPTPSFLLLPPLPHPIPPLLPTCHSPNYFPFPSPSILSSPHLLPPVYSPSFFLSRYPFLHPFSTHFYHTISFLPTLLPHRCHSLPSSIHLPPPTTTLPPPTPPPSTHPPLHHPYPSSPPSPPRTPLPHTPFGCSLSLSVFLSLSPSILSFNPSLLTSSYPSILLSFYLSVLKFGIEFYPFPLSLFPSVLSFFSFFPSLISFYLSIILPFFPSLPLSFYPILLLSFYLSIILSFFPSLPLSVSLSLLLSFPLSLPLSFSHSLLLSHSPSFLLSLGYSLLSFSPSLLLSFPLVLPLSFSHSLLSQYPSLLAFAYSLLLSFSLSLPLSFSHSLLSHYPSHLAFFYCLFFPSHPLSVSLSLPLSFPLSLPLSFSHSLLSHYPSHLAFFILSFFPSHPLSASLSLPLSLSPSILLLFSPSLLLPFPLFLTLSFYPTLLLSFYPSVILSFSPSSLPSCLSKDISDDFERTLKGLLIVTRRGSGEGLRKDFREDYERTFKRLREDFDMHVICVSYACHCRCVSDRNSRLEECGWNSSFRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7K7</accession>
    <name>A0A423T7K7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002156">
        <property type="protein sequence ID" value="ROT72446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7K7"/>
    <dbReference type="OrthoDB" id="6356992at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="642" mass="71386" checksum="107E9A1BD8EC7032" modified="2019-05-08" version="1">MRNAPSKTARQPPNVTNNQSQNRQGNKRSVQEEYERPRTSEVRNTRSVAVETDPDNIRSNVQGGHTQRVNAERVPSNRLQQPEQQSSNRLLSDDVNSSPFGESALQLLHQLRERLNTRGDSEGSNMVGVLEAFIGMRGSMGSVGTGNPGFQTDSASPLYTTVFQTPSSQPTSYGISQHPGITRCQQLRQEAGQPSCRNAASQQQNQQHQPTSQNPQANKRQENDLESKEASSDKTNSHREKDMEQLKRVIEHQRRIISEQENNIQELKTLSAHILAQKEEFLQAAQTHQNDKESRTNPKKDSTPTQSSAQNRDSGYGFEEVGKADTPVHSEDNSTEEEESRQPGRKAVNKQRKADRALRSSLLQLQTENQILRREVQSNRDLILNLENQLTRAYKEIDSERQSRSGLSISRLSGSAPNLDLIGHRNEAVSTKSRTNKRTPSVLGESEADSAYEEKSGSHLTSKINSPHSDGQQGKDSTIGSLRSLPIQSREIPERERTTVATTHDIPTDTALLQTGYIGKEMTVPHTLMNAATIPTSQFLLQNPVLTTQGNDYGETKESAGKVAPTVSEVSDEEKGRQKSSKPSRQLNNSRQAPLPKKELHPLESTRVKASFHTLSESHEFVALKGNETSTSSEFNSVEELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8Y7</accession>
    <name>A0A423T8Y7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008689</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002091">
        <property type="protein sequence ID" value="ROT72896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8Y7"/>
    <dbReference type="STRING" id="6689.A0A423T8Y7"/>
    <dbReference type="OrthoDB" id="10033291at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030054">
        <property type="term" value="C:cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045197">
        <property type="term" value="P:establishment or maintenance of epithelial cell apical/basal polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043113">
        <property type="term" value="P:receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097120">
        <property type="term" value="P:receptor localization to synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10822">
        <property type="entry name" value="PDZ_TAX1BP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050614">
        <property type="entry name" value="Synaptic_Scaffolding_LAP-MAGUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017268">
        <property type="entry name" value="Tax1-binding_p3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119">
        <property type="entry name" value="DISCS LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119:SF51">
        <property type="entry name" value="DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037712">
        <property type="entry name" value="Tax1-binding_p3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="123" mass="13433" checksum="52BCBCF4CFB18D52" modified="2019-05-08" version="1">MTTTAFSHEPGTAMECLSIPITLEKEAGLDEHGRQVLKCGFKIGGGIDQDFMKSPQGYTDNGIYCTEVHDGSAAARAGLRVHDKILQCNGYDFTMVTHKKAVDYIKKHPVLNLLVARKGVTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAR3</accession>
    <name>A0A423TAR3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Surfeit locus protein 4-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_008002</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002018">
        <property type="protein sequence ID" value="ROT73555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAR3"/>
    <dbReference type="STRING" id="6689.A0A423TAR3"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF1">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01339">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT73555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="270" mass="31026" checksum="C243FB642D52199A" modified="2019-05-08" version="1">MQNQNELLGRAEDFADQFLRYSKNYLPHIARLCLVSTFLEDGLRMWWQWHEQREYMDISWGCGYFIATLFVVINLVGQLGGVFMVLFRKKVEVACGLLLFIVVLQTIAYQILWDMQFLFRNLALVGGLALVLAESKKEARSIFAGVPSLGENKPKTYLMLGGRILLVFMFLTLVRFEFSVMQIFQIVIGGLLMALVAVGYKTKLSAFLLVLWLNVFNIYVNAWWSIPAYKPMRDFLKYDFFQTLSVIGGLLMLISLGPGGVSMDEHKKQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCF1</accession>
    <name>A0A423TCF1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001926">
        <property type="protein sequence ID" value="ROT74173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCF1"/>
    <dbReference type="OrthoDB" id="6359168at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="23334" checksum="0A8B6D6DDFD629B8" modified="2019-05-08" version="1">MSSSDQTPADCEVDAFIAGWKVGALAVEVLTSVFGVVGSGLSLWCLLSCKRIQEGMKLQLFLFFSLLFLTNLVAMPGAAVAELWAVQCRQVSAAVQMALVGFYTIVATMERNAFALMAAYRWVAVCWPHKYKILSLRVVVALLNGFVLGGVVILWLTVFLEQDLDTIDVSNPSVYKMGRELYFGILLTPMISALVAYVAVIVVVSIPSWLREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCK5</accession>
    <name>A0A423TCK5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001927">
        <property type="protein sequence ID" value="ROT74162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCK5"/>
    <dbReference type="OrthoDB" id="6776451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="50349" checksum="91F84C43C15B52C0" modified="2019-05-08" version="1">MKLNPPPSDELLSSAADPRVSSNDSMELSCTDQDGKDPPSADPQLQAQEQNTSANRGGSSSPYPLTKMSHKFLIALSKDFATAVEAMFAIEEEFPFIDVTTAITNDGHFILTPKTDSTRTLLDSLTTLASGKIVNITSYVPEPKIQSNFRKNPIGFPLQRLTDLPDVISAERCIYRPTKEETRQVLLVMSREPPDKINLGIFGTFRTRKYIPEPLRCYNCSAMDITATNVKLLHAVQSAQKVTQQTIASPNSKTASRPNQNAQTVEANTTHGTSAIHDWSKPREPQHLNTSALSHEPIKASIAANLHTFSTTAPAPVATSPVSQPFMSHKAPISLAPPELIGSFLVNTIQLGLLALGHSIPHSHLQTLIDNILAILPHKNTSSSSQESMPSEPVQQDTGTITSVVASSEDFPPLPTSSHRINQTSLCNPTPAQQSAQLHSSASSPPILHIPDQPHELRTTQELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG61</accession>
    <name>A0A423TG61_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zonadhesin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006037</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001774">
        <property type="protein sequence ID" value="ROT75431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG61"/>
    <dbReference type="OrthoDB" id="6382329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF75">
        <property type="entry name" value="CUTICULAR PROTEIN 62BB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="154"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="282"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="51826" checksum="C96DD267776BF30F" modified="2019-05-08" version="1">MLDSRGVEVEQGLQPSPQLFQNHQAFSQAFKERSEEMALQYSLGQVEYNDPNPEYAWAYEVDAKSTGDMKSAREERRGDVVVGQYSVMDPDGSLRVVDYSVAPGTGFQATVRKEYAGEAFQGQEQRLQAQARQYSAIQQGTDYQQNFGQYSQNRNRYQQNGEQFSQNYNEYQQNRNQYQYSQSRNQNLENTRQYSQNRNQYQQNRDQYQRNRFQSSQYSNDYQQNRYQNQQRNNEYQLNPIQYSQNLNEYRQDSNQFQNRNRNQYSQNFNAYQNRDQSYQNRNQYQQNFDQSYQNRNQYQQNRNQYQQNRNQYQQNRDQSYQNRNQYQQNRNQYQQNRDQSLSTRNNNLRYNFQRYGTNRFNQNLNRPSPSLYSQNQNYLLARYGSGSQSQYSNQYNNRVYNQYNNQQSRNQQNQGYSPISVVLASSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH48</accession>
    <name>A0A423TH48_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005616</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001726">
        <property type="protein sequence ID" value="ROT75830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH48"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="50500" checksum="A3D99A8718F9580C" modified="2019-05-08" version="1">MDFVRYLYALLMGFLSDVFMGEQARLAEELNARIRDAELRVSHLQAEADATILSRIRSFFPSLFGQDDGASRTATLASWALRGQASFAEKEAALEQLQDMAMSLEDRMEFERDCLHGVLMAAGLLVVLCALWRALRAFWKPAAHEPEDDTSRPDPERFRQRKPPGPESEEFGQRTHLPARIRRGSARGRQPPGPNPKRFGQRTTPPGPNRREVRPEDDTSRPESEEVRPEDDTSRPESEEVRPEETSRPESEEVRPEDDTSRPESEEVRPEDDTSRPESEEVRPEDDTSRPESEEVRPEDDTSRPESEEVRPEDDTSRPESEERFARRPHSRPGRGPWSIAERVALDLQGRVRSKAPQPSPAPRPAEVPQVAPWRTIALSLHFSARELCAALGPGLSHVRLVREWFPVRIRVPRRRGEPLVVQGPREATESAANFLWKFAAEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THZ5</accession>
    <name>A0A423THZ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras and EF-hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001695">
        <property type="protein sequence ID" value="ROT76096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THZ5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="134" mass="15585" checksum="5878F07EEC8515A1" modified="2019-05-08" version="1">MTSNTQVSKLYEELECQISGERSKVALEHSQKEARALASLETEVAEREAALRSLEEEQLKMRQRLEQVLAAETAARSENSFLSQHVEKLEADLNRREFEVQELQSTLDALKHRTKEEKRRRAHQAFKVRCCQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJV8</accession>
    <name>A0A423TJV8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001613">
        <property type="protein sequence ID" value="ROT76752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJV8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019324197" description="Secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="13272" checksum="9A9BCA6BFF0CCBEE" modified="2019-05-08" version="1">MRLSFCFLLLVSVMACSAMSLTGNGRGKPENPGNGKGKPENAGNGGGSSSSEEGSGSSSPEEGSGSSSPEDSGDSNSTSEESPESSPETRSSGDSSSDKSSGDSSLSIERGLRAEHDLDLNKLRRPAVKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLV4</accession>
    <name>A0A423TLV4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">B9 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003911</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the B9D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001524">
        <property type="protein sequence ID" value="ROT77435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLV4"/>
    <dbReference type="STRING" id="6689.A0A423TLV4"/>
    <dbReference type="OrthoDB" id="431939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036038">
        <property type="term" value="C:MKS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010796">
        <property type="entry name" value="C2_B9-type_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968">
        <property type="entry name" value="B9 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12968:SF1">
        <property type="entry name" value="B9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07162">
        <property type="entry name" value="B9-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51381">
        <property type="entry name" value="C2_B9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="23809" checksum="2080AC71970E3E8B" modified="2019-05-08" version="1">MSVSAPSIFMLNVTGQVESGKFIEGDNLYFSYCFTSGQDWEAISGLEECISQITRRSDDERQIFTWNFPIDITFKSTNPFGWPQLVLSIYGTDIFGNEVVMGYTACHLPLAPGKHTRKLTTFVPESASTIQKFMAWLTGRRPEFVDPKLIAQGRGREVTRVRSQGEVTVSFNVMMKDFAKLGYDCGAPPRTPYFDVPVQNVKGPVLSGAGHSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPD0</accession>
    <name>A0A423TPD0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001399">
        <property type="protein sequence ID" value="ROT78320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPD0"/>
    <dbReference type="OrthoDB" id="6353705at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019173633" evidence="1">
        <location>
            <begin position="26"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="310" mass="34976" checksum="D7F63FD94D5B1932" modified="2019-05-08" version="1">MASRHACRILLQIAAFMSAATVSCSEEPLLVNYMIPGSSLTEYKGDSSFIHISKADIPDRILISMCWESQNPKCIVHALTKETTLGYLCHNGTAQYTVKYQEEFDCMCSSGDREKGQRMYHDVFTYKSGPKWSITENRTKCVTSEFLHSVPESHTIRVKVYKSESIKITVCTEGIMPFKGNMFNRKYKDKFLYLEKEGINITYPLYKCENFSGDIKKKNLSQVIDEYNLSVSNGQETLVASLYNISRVVKQMIRGRRTTSTPLPTLEDPNYLSLSIMTDPPVNSGTFSSKVSVGLVAFAFCAGHFGRPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0C5</accession>
    <name>A0A423U0C5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024679</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000875">
        <property type="protein sequence ID" value="ROT82157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0C5"/>
    <dbReference type="OrthoDB" id="5969782at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="778" mass="89331" checksum="64C70BC8F7DDEB66" modified="2019-05-08" version="1">MRGGALCVAGPGETSLTRISPRIRQLQDRLMDSLPCDGAWECLSPAQREAILSIHRMRTASTDDSSEHGEGGGKGHRKGRGQGIPRFVRSRSYDDRLESETDDSGVRGVNGTSSGATSHNSHEDDSSDPGVKRGGRFAKAVSADRATRRDVKNEFHEMNNMKNMRKSEVTNGFGNVNKIISKQMNKASAMPSGPSNITLDCRNVQGEKRRRSRIDVNGLFREGSAERSLEAEPPRRAAPGSDSQQTRIGLTRRNILSETFESDSKLHSLKELKETASSEEYDSGVNFKNDDSMDEYVRDRQNGGCDFNNDFESDRTPRSSDTTSPSLQRKRDRSTDRLRAKGDDLTARKASAERDPFGGWDRDDKNRSREREVRSALAAAHPERPKSTKPNGEPLKSNMKVAYGAKLNSSFDYRTNLNQDQLNKYSTQVKKGDPNNWMMAADPRRTPNASQDRSAASKKYVRSKSLDRKYLDEDTSEEESDFETRRRTDRVRRYQRANQDWEVGRPHGGDERGRQRLRESDSPRKPKAKSAWDLSGQARAVRDDFDEFEEVGFRTRSDFRSRWQSEDSDVRHRKSSDNSEFGRMQWNRRSCDFDLDFPGEDLDRKSGDKDFDRKRWYRRSCDLDLDFDLHQNRQRREVEFDTEWGRQTLENCDDFEPEFATGKGKRSRSRIAEQQLVSLEAAGKGRGRGDEKGRRTRAEIESGRVTRLDGVDDRRLRLDDEPVRRVRMEEDHGRRTRLEEHYRSKTSMGHYGREKRERSRTPHLLRGKLRLLKSILSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1F0</accession>
    <name>A0A423U1F0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000817">
        <property type="protein sequence ID" value="ROT82494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1F0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="49511" checksum="BAAC2DFDD5708BF8" modified="2019-05-08" version="1">MRLPRELFRFARLFFEFWSVRSERGTSPLFPACPFVKPTSPLPSLRDRVFEEKTLMGKGFRLCAGKHERKTDDGKRSRTERSQQRTKTHASPARGPQRGNERPPRPHTETPPPSDPNGQRPATTHAHTTTEQPLTARSARHTHTTRARTAEHADARARTSRETRRRTTARRRTMDDDEHESPRQMREERREAAQSDNNEHRDAREQEPRRGRSTPQTHERETDRRARRERDDARHARRRKRESSRGRRRQERAPERIKMMRPPVDERPRERDAKRERERESTHERHRRGPQRQPEGRGRGPRETRQNTNKQANPNHARKRRLDKTEQSNSRRVKYDARNNDHLIPLLSVESRTLRQIICRSDHIPFYNEHHFSSSRRLGPGRDGPEEDVLNLPFKDRKDPSGCRSLLPCVIALDVKGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1G3</accession>
    <name>A0A423U1G3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_024298</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000807">
        <property type="protein sequence ID" value="ROT82539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6378400at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000045">
        <property type="entry name" value="ZFP69 zinc finger protein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008598">
        <property type="entry name" value="Di19_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF12">
        <property type="entry name" value="RB-ASSOCIATED KRAB ZINC FINGER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05605">
        <property type="entry name" value="zf-Di19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1226"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1254"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1282"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1310"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1337"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1366"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1394"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1421"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1449"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="1477"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="186"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="446"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="694"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="895"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="981"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1043"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1159"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="507"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="695"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="795"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="905"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="936"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1004"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1175"/>
            <end position="1187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1519" mass="165073" checksum="6947D9BAF86A96C9" modified="2019-05-08" version="1">MISSPFQILPKTSGACIGLPPVRNVLTQPGTTIILASLPGSHNVPQPNTSVLLPSTSAIMLSGPVGQQPASLIVPLKSPSKVGLAPATGRHHPPLLAPKSVLPKVEPVRPILQAKTPKKTIQGEEMRQGKEGGVGEVPRGSNVKSILPKVMPGDAHTLILVSARTPELLPSTFSAVVPSKITLGMNLSSQTQTSPQEGGQKGGKKRKERKKKPVLPTPQQEKGVASIGKTGAALEEKLTARRESQSKVVEKKASTKTFPSSSNVVSKSFMMLDDLKSKGCTTARPAAAADYIVSSQPDLCFPKQNLVDIPPPPYPKSSRNRSIDLVLQEVESRVQDWCSELESPNPSQGITKGHEEGFQTSYAAQFNTMDSSASMKGSCASPLYSTNANNELKICPTPVSSQLFSSSSPKPNLCFSPPTSPVYVAPVTSQPKVTFSMMQHESLANQMSPAYSSPVRSHQASSSSQVEDSRISASCQPQPPSYSSSSCVPQLNTSHSLSTSISQMNTSLNHSSSHYSDISSPLPETSSSLGIQKGVPSSTACFSFHSAYGDLSQASQTGQESPLPSITSSAVGPMCNQTPNQSVYSYSSKSSTAFRESPQPFSQALTSPFYGDSQQVLQSEHYIQSPHQASYLQSPQPETFSHTTHAVTYTQSPYTPPPHSVLYSEAPQSNIYNEPPHSVAYDQSKFFLRSENDDTFAQSPQPFTNTIASHQSPITNGHQSPQPASFSAGRINSFSDSPQPTAYCNSPQSTPTAVQSSAANSLGSSIPPLLPSYSFSEHTPSNYLSSSSPISSSMYNTHHTSLTPNPQVCEDTKGIPTNVTYTNDRVDCTGVERSHNPPSYEAHFQNNTAYARPNQPDAALSQQMAMSALDPDLSSYPMGCHSPRFLEQDLADMQVDPGSCVRSPPAYPSLPSLPPPPPPPSYTSNPHIIPPVHSSPYPSTSVQGSPYPATSTQNSQYPLASGLSNAMNEYNALDSASTFFPNTPPVMPPSTAAHPPMDSQPCLSQTSHSDSDGFSSCSNALPSSSFPSALYLPGDSLEDFEDQESLLKPQSRNIRPTDNQPAMHKQYSQESSTSLEAKGSKRNGAPGADSSQVHNIIERAERLWFIPHQEQNRAYIKRKELAKDFLNSSELQSRRDALLKEKFWIEEDEPIAQEIVLSATSSSASSGTNPSQEPNAKDPKDSRDLRDGKDLRDEAMASTSTNALMLRAGHMQAQDGKGKKKRNRELLCQVCGKMLKGRSSLRSHLNSHRSIQPHSCAYCPKSFTSRSILVAHLRIHSGEMPFVCSICDTAFRTQSGLHRHRSKHSTERPHKCSVCAKAFKTKLVLQQHLKLHLTGLFTCSDCGKTFERHRSLAVHKASHYHSSQRFPCPHCPKSYHFQSLLKHHMQVHSNEYKHVCSVCSEAFVWSSGLAAHMKTHSTTRPQCEVCGMRFASKKRLETHSLKHGNPKPHRCDICGRCFAHPYRLVSHKLVHEDHKDFACPKCSLVFPTAKKLRKHSAEHTKEEPRICPLSGTVEITKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U782</accession>
    <name>A0A423U782_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000526">
        <property type="protein sequence ID" value="ROT84573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U782"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="42738" checksum="E954003FB7B71216" modified="2019-05-08" version="1">MGIQGRVRSPAFSVLLVRPEDSSLEGARMRTLFSLRLLLGLSRLLGCFPYAVKLNPPKITFKKHLFAYSVVFIAFAITSTFVPVDEALLSETPVFLVKTKAHSHGCKSSEEAHHSPSVSVMERLRSVRLGLCDLDQLLRDVNDHFGPLLCVCLASDQLFVITFLQDLISNRNYSIFVSLIVVLLAFIRIFLVMNTPGMVIRELDEIEHDLANCPKFEVCGLFEIGRQSLLPKENVKVNELWCAVAHDVLIKDLEGARMQTLFSLSLFLDFSPLMGREVQELNPPNITFKKYLLLLAYSVVFIAFTITFQHSPSSVSAMERLQYMRLGLCAVHQLLRDVDDHFGPLLCVCLASDQLLLDEIEDDPANCPKFEVCGLFEIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7P6</accession>
    <name>A0A423U7P6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_022140</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000514">
        <property type="protein sequence ID" value="ROT84671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7P6"/>
    <dbReference type="OrthoDB" id="6374097at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001450">
        <property type="entry name" value="zinc finger protein 774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051967">
        <property type="entry name" value="Krueppel_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45925">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45925:SF4">
        <property type="entry name" value="ZINC FINGER PROTEIN 217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT84671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="93" mass="10030" checksum="E968E04B0FB35B5A" modified="2019-05-08" version="1">MVRAAAEGVPLEGSVAGAGDHPVGGANQYHPCSVCGRLFNRAYNLKKHLLTHTGEKPFTCMFCPYRAALKGNVTKHMQARHLDRLAPPPHAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSB7</accession>
    <name>A0A3R7LSB7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_019030</name>
        <name evidence="10" type="ORF">C7M84_019031</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ALG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003494">
        <property type="protein sequence ID" value="ROT63099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01003494">
        <property type="protein sequence ID" value="ROT63100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSB7"/>
    <dbReference type="STRING" id="6689.A0A3R7LSB7"/>
    <dbReference type="OrthoDB" id="17098at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT63099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="167" mass="19269" checksum="A705AFC278F28C4F" modified="2019-04-10" version="1">MLKIIRALDVCRYSPRVYVVAATDTVSLRRLQDMEKEFKERAKGPDEEDQYVVEIVPRSREVGQSWLSSVFTTAWAFVFSMLIVFRHRPSLLLTNGPGTCVPICIAAFIMRVLCLSQIRIVFIESLCRVLSLSLSGKILYRVVDDFFVQWPQLKAKYPRSIYMGRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZZ0</accession>
    <name>A0A3R7LZZ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">C7M84_018565</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003425">
        <property type="protein sequence ID" value="ROT63552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZZ0"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF36">
        <property type="entry name" value="INNEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT63552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="487" mass="55195" checksum="919FEACE8FD5A55A" modified="2019-04-10" version="1">MRERGTVPIFWARLRGVNELRKLPGTIDKYNPLRFIRPTQLIDPGVTDLLHHLPVPITLSRLKLGDREQVTRVHSVTFDEEGGSTSIRGERIKVNYYQWAPIILLVEAGLFYIPFAIWNSTAKNSGIKVGRLLKKVSVISQYTPGHPDRDALIAEFLDQFNTLMGVSKCCPGTVCKFDCGLACGGNPSSSLFILYMIVKIMYVFNILMQYFLLTVFLGKGYLFHGVEVVEKLINKKEWWTSPRFPLQTLCQVLAAQQGSLRTYTCQCVLPINLFNEKIFSFIWFFFALLLPVTIYSALIWVWRTFTCSRIAFVHYYLWRTRRVGKEDLYNNARKMAIQYLGWDGCLVLRLIEMNHGGTILTILTERLWEFYEGLERAQQDGGDPEAFLSQRPPIFACGPFPTQGPPTVTPTPTGAYGFYGKHYLPGTPGAYPGYMWNHQDMATPGYSGYPRIRGKISSAARGPPSASCYTWRLTVADASLTRSPASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M366</accession>
    <name>A0A3R7M366_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002403">
        <property type="protein sequence ID" value="ROT70631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M366"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="746" mass="84876" checksum="57BA69244C8D2F0C" modified="2019-04-10" version="1">MGNRKKQKRQQELCRWRMRWRRVQSAEPGVQRTRGTLDGRPVMCRSWPCVRVVFRRDLSSPERTHERTRILPLRPSSFLSPSSFFSSQFPSSSDGCVRKREEAYLGNESFFFRLLFNPIPHFLVFSISHFSSFSIPILISCLLYSPSLISSSLHPSSSLFPIPHFLVFSILFSLLYSHPSSSSLFPSLIFSSSLFPIPYFSSSLFPIPHFLVFSIPSHLSLFPSFSRLLYSPSLIFRFLSRLLYSHPSFSLYSPSSFSRLLYSHPHFSSSLFPTSSFHFLVFSIPIPHFSSSLFPSLIFSSLFPSSFLVFSISSFLVFSIPHPSFFVSISHLFPIPHFLVFSIPFLHFLVFSIPFLHFSSSLFPSSFLVFSIPIPHFSLPIHSRFSIPPHFSSSLFPVLHFSSSLFPIPHFLFSISHPSFSLLYFPSLIFSFLFPSPYFLVFSIPHPQFSHILFLFPPFLISYLALSLLFSSYLPLLSFSHLMSRPFLLFLIFLTPFPPLLILFPSDHLPYSHSSSSHFIFLIPFHPLIIIWPSHFSLFYLLILPFPPFLIPYLSFPSLLFSSSPHSLPPFFISSPPFPFFSHLCTPFPLLLLSSQLPLPPYDRLLPFPPFLIASPSSSPLLSCFSPLHLSSCPCVSPLHRLLLSLLPFLISSPSCPYDLSHPPLLLLRSASSTFLSLLPSSPFPLSLGPLPPPQLPSPSTADLPSSFFFVSPSYLSCRLFFPLHGDSTSLPFPPLIGYFTYPIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4E5</accession>
    <name>A0A3R7M4E5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_009027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002132">
        <property type="protein sequence ID" value="ROT72586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4E5"/>
    <dbReference type="OrthoDB" id="5956066at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="48395" checksum="50876E62446A0B77" modified="2019-04-10" version="1">MVNECRVKVGVSSGMDIDSYGFHFRQEALEGGHHISLSGDSAENNFYAEDEYRGAVELMLPAQTVHWNTSALCGSGDFDLQSRFTWNDLDQEVPAGNITQSEDTTLSALVELIDENVPERNVILAVDIHPYTENRTRDINATITQSFSGFAVNMDAQITDSNFHDGIYEFKYWSLTKETWENLHVSTRVEPSMDGFDFEARVKAPKGNWGYTYRGNAFSNDHEAAVTIMGISDRYGDFWEIETTVSKHLPEFTVHLDIGQENEEAYEKGRLRIGLHNPLEIGAALDHRKFGEWRQDGAIGLRLKTEDILQFVLEFDPSLDYQNEHFLVDLVSPADQIFSSWGRDLEYTTSAFAKWFMEESPSMYQVLVNNPTVVRVWNAEMHHFQEFVSEMNGVITDIHNDGQQIWNTVIQPSLNAVRETFNEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4M8</accession>
    <name>A0A3R7M4M8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative heme-binding protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002113">
        <property type="protein sequence ID" value="ROT72785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4M8"/>
    <dbReference type="OrthoDB" id="6424451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.80.10:FF:000002">
        <property type="entry name" value="Heme-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF1">
        <property type="entry name" value="HEME-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018728566" evidence="2">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22387" checksum="61DB01B2CC394630" modified="2019-04-10" version="1">MRTFAALALLAQVCQLALAIESAPYDLVNSAETYEERVYPAQKWVTTSHLSISHHEATNDVMFRKLFNYIDGQNDAAMKIDMTAPVTTLVIPGEGPNCENNFTMSFYVPAAHQDNPPTPTNPDVYIEERPELHVFSRRFHGFANDEDWIVNAAQLHDDLVAAGEEGVDFQTYYTAGYDSPYVIIGRNNEVWFMKNDMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M504</accession>
    <name>A0A3R7M504_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_009526</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">Component of the THO subcomplex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7. The THO subcomplex interacts with DDX39B to form the THO-DDX39B complex which multimerizes into a 28-subunit tetrameric assembly. Component of the transcription/export (TREX) complex at least composed of ALYREF/THOC4, DDX39B, SARNP/CIP29, CHTOP and the THO subcomplex; in the complex interacts with THOC1, THOC3, THOC5, THOC7 and DDX39B. TREX seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with POLDIP3 and ZC3H11A.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002208">
        <property type="protein sequence ID" value="ROT72097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M504"/>
    <dbReference type="STRING" id="6689.A0A3R7M504"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="10">
        <location>
            <begin position="2"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="9">
        <location>
            <begin position="72"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="8">
        <location>
            <begin position="364"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="679"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="405"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="687"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="724"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="740"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="768"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT72097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="786" mass="91051" checksum="B817FE868AE702E1" modified="2019-04-10" version="1">MLDSNPCLAEEIWETLKIYPYQHRYRLYGRWKNESFTQHPMLMRRRAWLLKKAKFIMMRITKETIKPVSRGIGKLTHNNPGPIFHYILIQVQLYDNLIGPVVDSFKYLTSLSYDMLGYCIVEILSENKDRTAHEEMIISPWLQSLSSFCGTVFKKYVTDLGGILQFVANQLKSEKSIDLLILREIVQKMGGTDTLEDLTAEQLSAMCGGELLRREAGQYQQERNTKRSSLRLKEALLENDLAIPLLLLMAQQRSSIVYNQTESPHLKLVGKLYDQCQDTMVQFGSYLFQVVTIEELSDRLPSIGSLLSDYHINADSRYDELRRQDRGEKKLTIEQKKDRYIQACNEVFDPIVSSIQPHFSIKVWEDMDPSFFLTFWTLTMSDLEVPHHMYEKEIKKIDANVSPSANKRKKETDRLLALKEKLQEEEKRQKEHVDRVYARLQQEKDGWFMLRGARSPKNDTVTAFLQLCLFPRCTFTALDAIYCAKFVKMLHNLKTPNFSTLICYDRMYCDITYTVASCTEQEAHRYGRFLLGTLDTVMHWHASQQNYEKECANYPGFVTKYRVSRQEANDYVDYENYRHVVHKWHYKITKALVTCLESGDYIQIRNAILILQGILQRFPVISNLAAVIEKRIEKVKNEERNRRNDLYVLANSYSGRLKGAKPNLMPETDFHIVPKRPQAAKVVNGASEKSSSTAANDVKSSGEMVEQNEKIVKMETSETTNGELEGKEDREAKEIKKESASVTSNASSASNKMEPPESSRGSKRRKTEHNSKVSMRVERDPLYLQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M684</accession>
    <name>A0A3R7M684_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein prenyltransferase alpha subunit repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_013673</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002707">
        <property type="protein sequence ID" value="ROT68196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M684"/>
    <dbReference type="STRING" id="6689.A0A3R7M684"/>
    <dbReference type="OrthoDB" id="5358702at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008318">
        <property type="term" value="F:protein prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF3">
        <property type="entry name" value="PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT68196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="47891" checksum="E0728E6C41824E6D" modified="2019-04-10" version="1">MRKGKIRKFNRFHYTNEVACVKRNRQRRKTSKLERTRYRNHNKPADFFLGFSHTSGFPLLLCDSFIYITGKVSTLTTMEDVTCERIMKKIEAVLSQDTLLDEFDIVFSLGEVNRSPVVHVEHKLGLESWCVKHVYAYAYAKIMGSKQTKRREDPAQVLRWTQFCLLIAPEVTTFWNLRKVLLGQGDLSANLELHFTRLILSRKPKCMEVFQHRKWMFKNVIAKVIPQQANGPNGIDPEHHNGNGVVFHSEQIERFLFAELDLCTWAANKHQNNYHSWNHRLWVIQQFATYVGLVDVCRAEYEESHKWISVHVSEHSGLHYLQYLLDSIVSLVNESKVENVSEIVPYVNSVTKLYQRELDFNRDLIEEYEDHEALFCHRRFLLTRLRDLLCSSPQRTCSPPPPALKRSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBT6</accession>
    <name>A0A3R7MBT6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kringle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_003728</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001503">
        <property type="protein sequence ID" value="ROT77618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBT6"/>
    <dbReference type="OrthoDB" id="6338524at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00108">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.20.10:FF:000001">
        <property type="entry name" value="Urokinase-type plasminogen activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050759">
        <property type="entry name" value="Serine_protease_kringle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261:SF7">
        <property type="entry name" value="KRINGLE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24261">
        <property type="entry name" value="PLASMINOGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00051">
        <property type="entry name" value="Kringle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00018">
        <property type="entry name" value="KRINGLE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00130">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 4" id="KW-0420">Kringle</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Kringle" evidence="6">
        <location>
            <begin position="5"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="19706" checksum="3A3DFB408A1583B6" modified="2019-04-10" version="1">MNLFGCYDGNGSSYAGAAAVTLSGRPCLSWDDPRINSLQGRAARARNFDLGLLGAHNFCRNPDGAQAPWCFVGPEAAEPCDVPACDAGRSVPATEMTQRSSTLLRPLNSATRPATFTTTPSTSPTTSRATTTTTTKIRCQPGEYTCENAGGCVPSEQVCDGERQCPRATMTPVQTFLAGLLSHFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCF5</accession>
    <name>A0A3R7MCF5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clavesin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCF5"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF208">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="80"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="206" mass="24500" checksum="B7F0636D3418B6D8" modified="2019-04-10" version="1">MKKFRIREAQELLEKYLHMRTENTHWFHGLDIKDPMIENLIDRGYFFALPERDDSGRRVFFSVAGCWSFHYITLWSPADVTKAFQCCEKTIPMRHKEIHFVNLPTALFAIFEFAKTLLSEKIKNRFQVHSDESKLRKKVPLRILPKEYGGTVPMAEMIKMYKKELTAVRSRVLMLDNMHIEKKVKHKKIGKAINTIQRNFRKLDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCP6</accession>
    <name>A0A3R7MCP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCP6"/>
    <dbReference type="OrthoDB" id="6334666at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="22575" checksum="DBF65253CC194476" modified="2019-04-10" version="1">MRRSRTKRHLSLCGAECNGEGKVSSGSSVVHVPSCRAWAQGPNIHFTPQPTMRGFYTCKVFHNRPEEIVNPVQDEFQLQMYAYYHDEYEMSASVENCTVSWNFTTPAMYPKPKITCGFWNNTANDLGQAIHGGLFYHQFVNKTWYAFMRDTPVMIEDIPRGSTLYCLTEVPFVNFTREVKVLRDPVNALLYNEGIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDM9</accession>
    <name>A0A3R7MDM9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Broad-complex protein isoform 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_002258</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001301">
        <property type="protein sequence ID" value="ROT79042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDM9"/>
    <dbReference type="OrthoDB" id="2311693at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016199">
        <property type="term" value="P:axon midline choice point recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008406">
        <property type="term" value="P:gonad development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035167">
        <property type="term" value="P:larval lymph gland hemopoiesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007526">
        <property type="term" value="P:larval somatic muscle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045476">
        <property type="term" value="P:nurse cell apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007464">
        <property type="term" value="P:R3/R4 cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045467">
        <property type="term" value="P:R7 cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF111">
        <property type="entry name" value="LONGITUDINALS LACKING PROTEIN, ISOFORMS F_I_K_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2" id="KW-0221">Differentiation</keyword>
    <keyword evidence="3" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="7">
        <location>
            <begin position="30"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="119"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="349"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="530"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="603"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="145"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="544"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="671"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="699"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="720"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT79042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="743" mass="80250" checksum="645C67B63C026651" modified="2019-04-10" version="1">MEDGLLSLSGTTQTTFFEILRVLREKANYTDATIAVDGKFYPVHKLVMSTCSEYFSEIFEKTPCKSPVIVLKDVRSQDMEALLDYMYLGEVNVNQNDLASLLKTAECLRIKGLAVPDEDTTKVRKAPPDDRQESPPPKRRRNEDNSSSAPRPVSPSVNAPSKTTTPSVTPPVQSLPGSQSQDGIQDSSLDVPPMVKVEMQEADDPDDYRKDNSYEGGSVNEGDMGSDFGAELSKAEHDPDSYGSGSYAGPSIQPGGDLPWDEGDSSSFPQEGFSGDLPAGQQPQGGRTMFDYLEHIAPPMGREGRRTVGKMELEEIQKRYLAGRWRPRRDPAHLTQKCFVTAGEAERNSARPVAGTDKNRSSGVWRGREDGGEGEGSCSDSIGLIEVVLVQAVLVKEVMVAVLLVRADSGRVACPVGAVGALVRPLPRVGSDVALELYLVHQILSLALSCTQSPPLALSLQQVLSLALSCTQKSLTGSILYTRSSHWLSIFAPICRDRPLAVGVGSRRIRGIIPPSAFFHISPPPPNPSLLTPPPSLLYPPPTSSSRKLSCPSYSPHPLPLPSLTPSFTPHPPHLKSPLSHPLPPYLPIHTFPLPPPHPHPHYPPLPPLPPPHPYPSLTLPPHPHLQATLPPSPPLKTTPHPPSPSIHTFTPTPLNPSLPHPSLHPHPHPSKPPYPPPLPPPPQHSLPHTTPKHSLNPTPTPLNPTPTPSNPLTPPHPNPSNHSLPPSPSTTLPQTAPPPQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDU9</accession>
    <name>A0A3R7MDU9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002082</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001276">
        <property type="protein sequence ID" value="ROT79202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDU9"/>
    <dbReference type="STRING" id="6689.A0A3R7MDU9"/>
    <dbReference type="OrthoDB" id="2129233at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043458">
        <property type="entry name" value="GPR158/179"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32546">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 158-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32546:SF29">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="12">
        <location>
            <begin position="38"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT79202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="27555" checksum="6EE6BB2AA27D7BDB" modified="2019-04-10" version="1" fragment="single">GLASRYELPGQFECLPCAEGCERCEDDSPCVVSLNWMMRTGILTLAIIIICSLPVIVVFTWKYGNIKVVRAASPALLRIIILGAFFIYSTTLVLYPIPSVISCSLRVWLREIGFSLSYGALMLKTWRISVIFRVRSAKAVKITDLDLMKRLGIIVGVFAVFLGIRTVVAPPQVIVSMTADDLKAFLCSTDWWDHSFTAMEIMFLVWGIRLCIMVRKAPSEFNESKFISIAIYNEFLLSLFLNVSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGB8</accession>
    <name>A0A3R7MGB8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000329</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001050">
        <property type="protein sequence ID" value="ROT80919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGB8"/>
    <dbReference type="STRING" id="6689.A0A3R7MGB8"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT80919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="42650" checksum="D8C265DD0D31B64E" modified="2019-04-10" version="1">MKLHFLGTGSSYPTTKRGVSSLALQQDDGSIWLFDSGEGTQIQAQKVAISRQKINKIFITHLHGDHMFGLPGLLCTISSQFGLTEEQLEKEVPHVDIYGPKGLRRFIYTALSLSRSPLIFKYCVHEMVPVASQYSEDWEDWDVDHSEPSATHPSELPGVTVEPSVMEDGNVYWKLIDNEEWCVRAGWIHHRIPSFGFVINEKDRPGTLDKSKLVSLGVKPGPVYGQLKSGKSITMENGDVITPEMVLGPPIQGRTLIILGDTSDASPLAHMIQSCDVVVHEATHDDTLVDKAVEFGHSTPSQAVAFSKSVGAKVLLLNHFSQRYSPSSKESLKEGEETVALLEEQAQAAAAGTGLSVQCADDLFVYEVPGTRRANTRIIGGTHGWRSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MH90</accession>
    <name>A0A3R7MH90_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Centrosome-associated FAM110 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_025143</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM110 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000932">
        <property type="protein sequence ID" value="ROT81692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MH90"/>
    <dbReference type="OrthoDB" id="10028183at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025740">
        <property type="entry name" value="FAM110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025741">
        <property type="entry name" value="FAM110_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025739">
        <property type="entry name" value="FAM110_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14758">
        <property type="entry name" value="AGAP005440-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14758:SF1">
        <property type="entry name" value="CENTROSOME-ASSOCIATED FAM110 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14160">
        <property type="entry name" value="FAM110_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14161">
        <property type="entry name" value="FAM110_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosome-associated FAM110 N-terminal" evidence="4">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Centrosome-associated FAM110 C-terminal" evidence="3">
        <location>
            <begin position="375"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT81692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="51715" checksum="F01C4DAAE1073D8D" modified="2019-04-10" version="1">MSMGWGGMVVGPGWWGGGGGNKSAVQLLQESKSRYVKSDQVLGNRQAPARPDHLQISSNPNIFLSAPSHTLHVSRPSPAPERRHALADHNSVANIRGHAPTGLSPPRPQPAAGPASLGVQPPPLPARSPRITPRPKVRLHGDAQTGRAGGDLRRSLSHGPGDRGDDVQMKLRRLLNTDSRENLAAILTTPDSKDGKAKIPPPPPRRNIKSSPSGTFRAEPATVTTHKSLPDLARASSPAGETDSECGTSGRRRPSCPEALTSSNTPPEPPPRPPRMFRDPPPPPPQRSPDRPPARPPPPRDQKDSSMNLLRAGATGGPLLTADGRRSSDSDISGYGGTGNGVGTSEEGRRRPILRSRSDVTHERGRWEEDVRPMLAPLDLEAFFESMGLDSVTRQHLTSPPSSPHSSPVYFEEVSSEESGPTGGRRGSSDSDDGRAATGPGPGPPLPLRGTGEPSIVEKNARIIKWLFNCQKAQGTYVSRVASTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ31</accession>
    <name>A0A3R7MJ31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_019106</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003504">
        <property type="protein sequence ID" value="ROT63027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ31"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000761">
        <property type="entry name" value="Zinc finger protein 449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000202">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408:SF58">
        <property type="entry name" value="TRANSCRIPTION FACTOR (TFIIIA), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="337"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="439"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="712"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="741"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="770"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="798"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="826"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT63027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1024" mass="111311" checksum="270CD5814039B3E7" modified="2019-04-10" version="1">MNNVVVEEASRRRPGISLSALEGLPAAPVTPAHVSLGEAKAVVTLQEAAGNETMVALQEAGENEPLILCPLEEPGAAGVRQGHAHHHLPTGATLTYAALDEGVNIVLQPLKTEPHAHASPVGLAGDDAHQGESQGEQEGGVAPADAHTITLNSADGSTLHTLPAAYTQHLEHAYGDLVLDGDGGADEGRRPDEEVLLLSARLATRDSLLPPRRNRRCGNPGGLTCPVCRTQFKSGRQYHGHLHVHRGHGVWQCDMCEHTSDTAVALSLHKSEAHHEARPYKCPHCALSFPKSLMLEDHVRSVHNKERPYTCSFCTKGFYRPHDLKMHLNLHLGIKSNVCHVCGRQFSHPSNLIRHQRLHTGIKPYVCFTCGKRFTQVTLLHQHRASHQPGAGVCPLCPATFRSAAGLRKHSKLEHKKPMTLQEAARIIRGQRTSTGRSYYCQVCGAQFSIKSELKAHEQQEHGDSTEHRCASCNKVFSTAEVKSHTCLTAEEEERRNRLLGPQELSTSAALTSITATPGERVSYVVKKGTKSSRNKVLEIDAARPDALSEDDFPRAMLSEKTIMINVQDRPGLLQDGQTMMSLPPEIEEGESAPAGLGGGEDSASGLDHMDADKAALPLASIKLEPQTEDDLDQMTLPDKALLPIVSLDTLSPPAKVSRKPGLRPISAKKSRNIALKGECDDLNLDEDTKVFQKRWNFQQHIATHDASLHKYKCDTCGHTFAYRSTLNKHVLKHRSPPQLHPCQLCKKTYKRPASLKQHHKREHMQQRPYVCELCGKDFFGKSDFKYHMRIHKKEQPYMCFACGREFSHLSHLHRHERIHTGERPHKCPYCPKKFIQLVTLKIHLKKHEKLAPEELKPADEGLRGKEEVSLNLGLGEELVGEQANLVAAMDESLCNPSSATSLGVSSANAITTSASTISASIAASQGSAEGEEENSGALGVHTNSDLGLERALSTNAAALLANTSASAPRLTMDGFPPGTVILAQGGLEDAEGGGQFSGGHTAVVAGVNGDCIAIFVQDANAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK29</accession>
    <name>A0A3R7MK29_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001330">
        <property type="protein sequence ID" value="ROT78800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK29"/>
    <dbReference type="OrthoDB" id="6346795at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018712615" evidence="2">
        <location>
            <begin position="22"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="739" mass="82084" checksum="5541BE84A5B02EC7" modified="2019-04-10" version="1">MARSKPAISILLLGLRSVCWGLQFDDKRVTFPRNLEVCSVRRSDSDSFLSEVHIRSLSGGSLPPTATDVTLKTSLPSCRHHAVTSFTHASANVSVTWSCDDLTAPAPGQLRGQVNTREKGEGLRLVADLAHKDIVVTSSGVELAFRGDQVTSGDLKEPASWRLRAQRRIKTDQTSRCSHDDGPVGGESHFPQCTPTFTEPNELYHGHGGDEVHTKQPEHFEGVEFEAQVSKGEISIKSRSPLGERRLLAYTSSTEDPGASKWMLHLPTLNLRLNATSTSWYDHLKDHSYFEAEMTNLLTKTSVKITSKEVLVQQKDNLDDPGKQVQEENKGKEAVRSHPTEAMEAGSEGDLVADSSSQEDIKRAKRHLDKGQVGMDFQGTEGSSGESDLFPTVLPPNCIPGSKLVKQVQQTVESSIFNMETNMTVDVTPDGEHIIGILQKGSLPVCPDLGWDLKQIANFSSSFTGWEYVVSQWSWGSMVVEAQWGVSFFQDYHKIFAFNTDQNSPLPSTHILLDFRDYKEFQVKAKCPTLGKSLVFTLHNDANHHTFMVRSINEFMPLDSSTLIKVDVKVIHSDLAVTWYFDEEKAFSIWSKLTEAVLEAISSTSFCGQNAFKEKVKTFITGMFGDTPLQLMPEVWALLTLVKEVEELQDLKVFFNEINQDVFDFLSLWSNLMASGYKVGILEAHPQGMGVTVKTQGIIWVFSTAMDALNAVSGCSNNCDTTYQLSRLIEDFAATIRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKT1</accession>
    <name>A0A3R7MKT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKT1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="44816" checksum="1E62A510618FEDDD" modified="2019-04-10" version="1">MCQPPSEYKAGQQGVSPPSEAALREGAWLRSAECPLERLWALATRVGIHTLGDSGDSELESIYVGRLGVGIHLRWATRSWNPSTLGDSELESHLRWATRSWNPSTDSELESSTLGDSRVGNPSTLGDSELESIYVGRLGVGIHLLVYTILPNHFPLSSLLHGSLSLILLHLSPLPYLDVLPPPPSLLPTLSRRVSPFQHFTAIPLGFFTSHSVRFRPSLPPSLSSFRFLPSFLSSFVSSSLPSIFSSVLPFFVLPPYLPSFLLSFLSSSVHSFLPPSLTSTLPTHFILSFAILPLPSPCVFLSFLALSHVPLRRLPLSRFHSSRTGNEEGRDPRSLPQDFRGEGATHNRLQIPWREGHGTKDVGGGGKTRRVDEEKVSHEECTEQKETERMGKGKKYEVKQGEAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-11-27" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLA6</accession>
    <name>A0A3R7MLA6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_001463</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001185">
        <property type="protein sequence ID" value="ROT79839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLA6"/>
    <dbReference type="STRING" id="6689.A0A3R7MLA6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF1">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="84" mass="10122" checksum="759B81190DCA23EF" modified="2019-04-10" version="1">MHPDLSPHLHSEECNKLINQLHDCHNENRFMKFMGVCNDFDRAVWKCLKAERIARRTRNRVSGEEHRKKVLDKIQEGHTWNKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLY6</accession>
    <name>A0A3R7MLY6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="11">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_016872</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10 11">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01003128">
        <property type="protein sequence ID" value="ROT65176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLY6"/>
    <dbReference type="STRING" id="6689.A0A3R7MLY6"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106143">
        <property type="term" value="C:tRNA (m7G46) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000060">
        <property type="entry name" value="tRNA (guanine-N(7)-)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3 11" id="KW-0820">tRNA-binding</keyword>
    <feature type="active site" evidence="11">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="48"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="182"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00060552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT65176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="209" mass="24200" checksum="EC0C98974C68AAD8" modified="2019-04-10" version="1">MDWSPYFPKYFPGDIAKKVEFADIGCGYGGLLVTLAQVFPETLMLGMEIRVKVSDFVVDRIQGLRDEKKEVPGGYQNVACIRTNAMKYLPNFFEKGQLSKMFFLFPDPHFKKAKHKWRIINSSLLAEYAYVLREGGLVYTVTDVKDLHDWMVHHFTQHPLFKRQTEEDLTDDPVVQHLFESSEEGQKVTRNSGDKFLAVFRRIADPRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NB82</accession>
    <name>A0A3R7NB82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000832">
        <property type="protein sequence ID" value="ROT82389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NB82"/>
    <dbReference type="OrthoDB" id="6361735at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018706297" evidence="1">
        <location>
            <begin position="16"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="300" mass="33116" checksum="00A00D6EC3544E79" modified="2019-04-10" version="1">MALALLPLLFSVVLAEDPFYIELSAQFPVALDPDGSDQYLFFIVPIQKSDDLNVVVQVAQVQDGSYLRNDSRAAITAEAENNDVNVSRTFSPELSLDDVFRTGEEDLEPEFNFQVPVVVPLNFPFRYNPWDGSPELPNCAVDSRTWMENVIYRISTTMNLDYDPQWDHTDLTLRIRLLKDKLAATSVEDLSTSSLLSDFVTKIVSCKALAGARTSAILQNIDSLTADYSGVVSEALDTYRLLGRSLALASVAAGLLPSSSEVDVTVRQINLSSSSVDTTLVQLDAAYELVRQMQSQEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NME5</accession>
    <name>A0A3R7NME5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">1-aminocyclopropane-1-carboxylate synthase-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003880">
        <property type="protein sequence ID" value="ROT61992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NME5"/>
    <dbReference type="STRING" id="6689.A0A3R7NME5"/>
    <dbReference type="OrthoDB" id="10262468at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050478">
        <property type="entry name" value="Ethylene_sulfur-biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795:SF39">
        <property type="entry name" value="AMINOTRANSFERASE CLASS I_CLASSII DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43795">
        <property type="entry name" value="BIFUNCTIONAL ASPARTATE AMINOTRANSFERASE AND GLUTAMATE/ASPARTATE-PREPHENATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00753">
        <property type="entry name" value="ACCSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="3">
        <location>
            <begin position="69"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="48975" checksum="3FA0492905570460" modified="2019-04-10" version="1" fragment="single">MKLEPASHLSQRGSHAANYGDFIMTYFKEALKNPYHPKLNPKGIINMGTAINRLMETELAARITQGDALAYTPAHQHYYELSGTAQLRQALAGFFTRHFCPGRNVSPDNLVVMNGVGACLDSLGHALCDPGDVLLTPTPVYGRIFTDFCDRSLVCVEPIDTSQETNVDGMTFDLRPEDVEERIVQLTSEGKRVRGLVLLHPHNPLGTSYSPELLRKIFAVCARHQMHVIVDEIYALSVFDTSAPHQSVLSLDDLPDPEKTHVLWGLTKDFALAGFRVGVIHTQSKELLQCLRAVSTYQCTPHLIQHAAATLLNDIEWCDNFYLPTNQRRMQEAYTKALKRLEGMGVKVRRSQAGFFVWANLQSFLCPCTEEEELKLFEELFESGLFLVPGSKLYCVNPGWFRFIFTIAPEDLDEALNKVELVLCRRRTPRKHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NN75</accession>
    <name>A0A3R7NN75_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019739</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003691">
        <property type="protein sequence ID" value="ROT62419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NN75"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="524" mass="57248" checksum="8E9007BF3ED1CBCA" modified="2019-04-10" version="1">MFFCFPLSSQPAGRAPDSPAYPRSALTPFHLASLLSLGPSPPYRPPPCNPASPSPLVPSSLSLSSSPLAHSIASPRPLSKLSALPPRRLVTHDAFHSLFFRSLFLSRRWPIDSDIGPLPRLPFASLPLSRRAVSHVAFPVPSLFKESLPYFRRSHRAGYERSGNLNSRAAELRRVRGGARGGGREASFRAFDTPRGLWHDPTRPAPFSHRCLPPYPYLFRKCLCLSAPSSSLPRGLGNEIAIPGLAIFGGSRLRLEIRVLFENAVTFGAESFRRVQSWKWPEVPPRRNVARGMRTGGRGGVGAGWRGCRRPFSLPRSLDDRSWLSRLRPCPGSRVPHVVTAPSSRGDRPLLSRSFTTVPPRAPSPAGGSADFRVDNDYERDYLPLNSGFAPRAVFKFPSRRARPLRPSVCAVSCSLGLPLSLSLAPSFGPVSVHPSLAPPVPPLFLLSPFFLFIPPSHFPPLPSSFLLPSYLSLPLFLLPPKPSSLSPPSLHFPLFSPLLPFLSTCSRPLSHPPIATNNAAPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NQ35</accession>
    <name>A0A3R7NQ35_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018352</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003384">
        <property type="protein sequence ID" value="ROT63755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NQ35"/>
    <dbReference type="STRING" id="6689.A0A3R7NQ35"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03428">
        <property type="entry name" value="NUDIX_Ap4A_Nudt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000327">
        <property type="entry name" value="POU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003565">
        <property type="entry name" value="Tetra_PHTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01405">
        <property type="entry name" value="TETRPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51179">
        <property type="entry name" value="POU_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="POU-specific" evidence="6">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="146" mass="16825" checksum="3A2328AC6B872369" modified="2019-04-10" version="1">MSGLQELRAAGLVIYRCVATEIQYLLMQASYADHHWTPPKGHVDPGESDLETALRETQEEAGLSRNDFTLIDSFKKELKYEVRGKPKTVIYWLAELNNGSKEVTLSEEHQEYRWLPLAEASSLAKFPEMISTLEESEEFIKKYKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NQI0</accession>
    <name>A0A3R7NQI0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metalloendopeptidase</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_017996</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01003331">
        <property type="protein sequence ID" value="ROT64078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NQI0"/>
    <dbReference type="STRING" id="6689.A0A3R7NQI0"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF850">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="11">
        <location>
            <begin position="17"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="10">
        <location>
            <begin position="263"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT64078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="44167" checksum="DA9F3DEF7B68F712" modified="2019-04-10" version="1">MDMMLTPEQEAMLHGKRAAGDLTTLWEDVDGFPLIPFTFTDHEVDRTPVLLAIHVWQASTCIQFLEVETDYVGPHLRFQRNGDACMSNVGRDSSTGQDVYISVACEMSHGMLLRILGHAIGLWNEEMRSDRDSYVRIISNNVLEDELGFFLINGDDTHGVPYDYCSIMHSHERIFTGNGEGTIATLDPLYKSSIGRTQGLSHMDLLQANRMYQCSDKLQSECSLASDPCVNYGFLNRSCLCACPEGTSGDFCETMTNTYNGNCLMPLSEVITEPTTIVSPSVDRSLWEDPTEIRFSKYIQAPANHVIVLIFDKFDIYPRTQHYVAEDMAVDMCWYDSVELCLDNLYDGEWYCGTELQGQNITSVGDSMVLHFLTRLNFMPGFSVTVNFVEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NS05</accession>
    <name>A0A3R7NS05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016851</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003122">
        <property type="protein sequence ID" value="ROT65200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NS05"/>
    <dbReference type="STRING" id="6689.A0A3R7NS05"/>
    <dbReference type="OrthoDB" id="5586at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="940" mass="101007" checksum="5A97F632B7D633A7" modified="2019-04-10" version="1">MVENVGGQCGRAAVTRVASSRPCDAPAPCPAHYGLCLPVVVNLTDPANALGTVQPDKDAILDIVEANRRKQAAARTRKASGDSHSPQQTSPSPLGDSPTPIDTLQQAGQQKQQPSAAESWRIARAVQRWAQGFGKGERERDSREEERKYEEGAGTLAELAAEKRAGRAAPGPEPPTGAPRHHEAVQLFSELMQTDDVSTIAAQIANQAELIYQTWKTTGLNPTELIRYHSVTSEGSLFQGGEQSASAGDPHTPSTPSTPSPTAKPRTPARSISPAPPGSSPAVPRKVIEPSLHNGRPHSASPVRTLNTSPRPYIPPTSPRLSYASPASPSLSQGSPRPYVSPAAPQSPRGALTQPPPPPERSSSYTGVDSSPQPQAQQGQDSPFDILADPELEASLQELVNSFVIEDKARHHAAAVAALASQRPKSAPSSIQEALQRFERQMAITSRAAAHAADNVSNSSSPSASPNAMGTLGSESAARRRPQRLRLDPHAQRRRGAQPALGVTQPAGVAAGLERGPLRQHLHVAAQEQAAQCRGEEICAEPAHGLAHDLQSGANSNTTTNYITTLEARVESSSSQKFSGVPLRHKVVTMAAVDKEEERLMHALRTGTLIDDGDHLRPLGQARPTSAPVSSPQTPLHTPNSTIITSATPNSLPNQTETQEFPAQGRRPKFSISVTKVQKIASSSTSSAVEKPGSPVRMAAKNPTEGDMSIVDFAKVRFQESQQHPHSTQRLEDYRNMSKQVVSSDGRVMMARTRFENGSTSLSDSVWRGTMGIQADEVGSTLPEFYRRKLRKMRKAGSPEPLVAGSISTLPHPELTDQQKAHIRERSQSPTTGYNSAGVAIRPFLTQGSVAERVLIFERAPAEMKPKPSTGAPVPEKRRPAVNTWRDPDEVRSYVQTQICFPSRACSHSVYFFVFLETSTASSFLGLRLRRGARYVLAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCB6</accession>
    <name>A0A3R7PCB6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trafficking protein particle complex 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002922">
        <property type="protein sequence ID" value="ROT66529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCB6"/>
    <dbReference type="STRING" id="6689.A0A3R7PCB6"/>
    <dbReference type="OrthoDB" id="10262857at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="181" mass="20535" checksum="E08522E4E5A15573" modified="2019-04-10" version="1">MSRQSMRSNDPKKVSGELFTLTYGSLVAQLLKDYENVDDVNRQLERMGYNIGMRLIEDFLARANPGRCYDLRDTADKIQQAFKLYLGVSPSIGSWSPGGDEFSVVLETNPLAEFVELPDHCLSLRYSNILAGVIPPISHLRILAHLPRERWKSLLTGLRKDIECSSIVYSHLEVEKGMFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD41</accession>
    <name>A0A3R7PD41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative TBC1 domain family member 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003913">
        <property type="protein sequence ID" value="ROT61931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD41"/>
    <dbReference type="STRING" id="6689.A0A3R7PD41"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="468" mass="51638" checksum="81A8E114415475E2" modified="2019-04-10" version="1">MSLNGILRRASSFLGITGTDSSKQMYEDGDIVFCKNNVCVHPPSRYRCDGERVHHPGYLVIKCRADSTLGTTLHLNWIPNDRLRRNHELISQMNLEGSSSSNSPCPTSDSESLSVSSLVLHDGNSAVRKTSMDDAAMSTSGISSMDTASEVTQPKDENSPNSEGSSSVEQHKEKDEGDGGETTESGDPSSEEKDERRNEEATSEGEGERKDEWATVENEEKRDEDMGEEKGAKSISDEEENTETGDEITKDSQESSSGDVEEVDKEGTLRARDMHKLRYISSDSSSDGEKPAETLTIAKGKGNPLQGRQLQSEGEDSLDSSPEPQLSPTPHYFTSSSGDQYWYERSAESMAYSANLAFPDSSLSSFCPTPVDGGSSPIRREHKCGIFSIDVSQCRSLRLFFSDREHTCGQLVIASQESQYKIFHFHHGGLDKLASVFEDWNFLVKPQDEECKAMDSALKQFMVCRYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEN7</accession>
    <name>A0A3R7PEN7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Focadhesin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002652">
        <property type="protein sequence ID" value="ROT68625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEN7"/>
    <dbReference type="OrthoDB" id="6354723at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021392">
        <property type="entry name" value="Focadhesin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11229">
        <property type="entry name" value="Focadhesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Focadhesin C-terminal" evidence="1">
        <location>
            <begin position="95"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="525" mass="59170" checksum="4D97BF3A54DDFD70" modified="2019-04-10" version="1">MLPKYAREGHQLPPSMAATPFEAARNPVDVLDYVPAVGWIKLMKGCPEAHIPYVQNFIKSLVAREVAGLPKGIYMTAVQEAKRRGVKGSGGQPEPPSYSFLKDTSTLRTLVNFLIDFPDMLENCTEVDAKKRLLRCAVLAMESLGQPLPRPYPALDWIFLEKVLSAAQSVSNSDWTTRIRHSLFRIAARQSNKSPSACNLISQWMLPAPTNGLTKEDEITLFGLLDHIGRGVPPNFLQPFIAYIFQQRISDPSHMKALLESVKPVLTADFIFDTNRNVLSNAIEHLNENMDPTDEAVYNTYKACVADLPQKHIERLTSPSLWWEVTNERLYRAAVLRCHVAEKDPEEMALPWLNDLVDSAASLPGDRSHLLSVMSNTLVTRCLVNESTSWFLQLLGRLRDHLKRKTDDNLVAMHEQQQRITFYLDLLVMGLIVWSGLWATNHMQVLAETPALRDRLLLPSLVTLSGQPAWVQTLSQFLNWMVSCHTLLQNYNASRYHLGSPTLLLATLNPSISQVMWNKVIAMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PID7</accession>
    <name>A0A3R7PID7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002089">
        <property type="protein sequence ID" value="ROT72921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PID7"/>
    <dbReference type="OrthoDB" id="6370792at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="577" mass="62630" checksum="3F89CA69DF84E332" modified="2019-04-10" version="1">MWFGLRKVEGPGGGAEEPFRRQRALRERLRHAISAPPALHSGPVAPERGLASTPRSWGFLVEVEQTSFPLTWRASGIVSATPPLCRGSPVVSSPPPPSSSSSCVLGGTPLAAEDAEGEVPSAPISRTLEPEHFFYMTNPPSSAGLASHEKGRFDDAGASGPVVLTSSKQVLDKARGRASQEDLRASHSSPDASIPYPKTRSRVPSLGGGHHQRPSERKKSPDVVGGVPPSHASLTTFSGLAFQNLSSSSFLFPSSVVVPKTVVIPSHLISRGVGWRQAEGVTSASRPRLHDAVSLIAPSTPILREYPFSSVTQTHGLIHRALEGSSPLVPQVKGMDYPKSRWFPYREERLDKGREHYVKLAERDSSLDRLGLRDVSSPYSSFEDLTAFRTQEISTGTSELFHAGHEVPCRGCATQEFRAGDMTTNPVTIVLTSSHLTFPEPQTRGILHLADLPAEDNVTSNTTSSLGRNSTSEIPITVPPLDVPEPSTKFSSIGHVTSCIIETRMSVHRHEIHTLQQIWSSASPVWFPEPQTIMRHRAEEVASNEDLVQALTLESSLRSYPDVTIWSHELITPMTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIK9</accession>
    <name>A0A3R7PIK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008504</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002070">
        <property type="protein sequence ID" value="ROT73081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIK9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="45350" checksum="7CE299D4D4653DB3" modified="2019-04-10" version="1">MKLRTCRVVPSCTHTRERCRGFHKGLSLNARIHKRPFPPRPHKRTFSLHAHPHRLYHKRRFPSTAHPQKAFPSTALHQKTFSLTPIATRGFHEEGLSPSTPIHKDLSLPPPNSTTRLFLHAHPHSLPQRPIPLHGPVRTKEPFLHAHHKSPCSLHAIHTGFHKRPFPSHAHPQKTFPSTPIHKRPFPPRPSTKDLSLHAHPHRLSQTAFPSTHHKRPFPPRHPQEPPSTPIHQGFHQGNFSLHPTTKDHFPPRPSNRLPQGLSLHAHPQETFPSTPIHTGFHKRPFPPRPSTKDLFFFLHAHPTKGHFPPRPPQRPIPSTPSTQAHKVPFPSTPIPKRPFPPRHPQKSFPSLPSTKGLSLQPQSTQPSPRGLSLYAHPQNTFPSTAPPPPADVKTSSKGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKR4</accession>
    <name>A0A3R7PKR4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002524">
        <property type="protein sequence ID" value="ROT69729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKR4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="644" mass="67594" checksum="363E4FFBA770B853" modified="2019-04-10" version="1">MRSTGGKAAQLPPATRSPPVPRTQAPLPATQSQVKPRPSAPASDKVSTGPRTQAPLPATQSQVKPRKRQTGHSLNHRFSSRQRQGLHRSPDASATTGHSITGKAATPSAPASDKVSTGPPDASATTGHSITGKAATPQLPPATRSPPVPRTQAPLPATQSQVKPRPPQLPPATRSPPVPRTQAPLPATQSQVKPRPLSSRQRQGLHRSPDASATTGHSITGKAATPSAPASDKATGPLPATQSQVKPRQLKDASATTGHSITGKAAQLPPATRSPPSLPATHPRPPQLPPATRSPPVPRTQAPLPLLHRAPHSRRSHPHQVTGTSPHQRPPQDALPSVITRMFGTVGVPPMVASFKPEADSLSALPRISETSGLSRLVVSLTPEDELPSAAPHVSETIGVSHLVVSLKPEDGLPSVPSRVTVICYDSAVDIRVKPEDGLPSEILRASEASDASIRTFFFSGPRLTAPTPPPSLRGLFGAGERAIYGWHGIDDFRLSERLASVALPAPRGKGWSLFTLDQRQRDPCPPRACQGVPYCKVTHPQVAVLDLPTPTRATSVTHALGLPTPAAPVASHTLSIVLPSTSRNDARTDLTVGSALTPPRACQLSFRFCILSPLTASFAHTVDYTLVDPLTSPSLLKGLAFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN54</accession>
    <name>A0A3R7PN54_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TGF-beta family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004008</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TGF-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001535">
        <property type="protein sequence ID" value="ROT77352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PN54"/>
    <dbReference type="STRING" id="6689.A0A3R7PN54"/>
    <dbReference type="OrthoDB" id="5987191at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13761">
        <property type="entry name" value="TGF_beta_BMP5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.90.10:FF:000001">
        <property type="entry name" value="Bone morphogenetic protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001839">
        <property type="entry name" value="TGF-b_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001111">
        <property type="entry name" value="TGF-b_propeptide"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015615">
        <property type="entry name" value="TGF-beta-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017948">
        <property type="entry name" value="TGFb_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11848:SF310">
        <property type="entry name" value="PROTEIN 60A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11848">
        <property type="entry name" value="TGF-BETA FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00019">
        <property type="entry name" value="TGF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00688">
        <property type="entry name" value="TGFb_propeptide"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00204">
        <property type="entry name" value="TGFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00250">
        <property type="entry name" value="TGF_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51362">
        <property type="entry name" value="TGF_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0339">Growth factor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="TGF-beta family profile" evidence="9">
        <location>
            <begin position="218"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT77352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="340" mass="38188" checksum="886F64FE8FB46522" modified="2019-04-10" version="1">MVGHHRHHHRAHRAHGSAPTWMKNIYNTLDEHGHANAPNMDDVHRETVTAADTIITFVNRDPPTGRPAHGANKRLYFDVNDVPLDHSLLGAEIQVHRQPGFDEVVTLHVYVVTDEQGSESKVARVSLSEPGWVTVNVTRPVLSWLIFPDTNYGLRLAVTSPGYKHERHFHEVGISGSHDEEDYRPFMVGFFALPASAHKKKRIRTARSVARPAISKPRKYRDLADRQVGSETACKMKHLHVSFRDLGWEDWVIAPEGYDANYCEGRCSFPLHAELNATNHALVQTLVKVVGDVADETEVPPNACCAPIDLATIPVLYYSFDNNIVLKKYPMMIVKTCGCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNG8</accession>
    <name>A0A3R7PNG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GTP-binding protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009461</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002197">
        <property type="protein sequence ID" value="ROT72156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNG8"/>
    <dbReference type="STRING" id="6689.A0A3R7PNG8"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF43">
        <property type="entry name" value="GTP-BINDING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Obg" evidence="8">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="120"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="346" mass="38598" checksum="8CFDF3C5AA74B38D" modified="2019-04-10" version="1">MGYPRFGGVGGNGGNIYVEAKEDCNLLKTLKARPDKRWCSDSGANSRQFRILGEQGKDVCIPVPVGTSVRLDDQRLIGELNQIGDKILVARGGVGGSPNNQYNGQKGQAHHIILELKLIADIGLVGFPNAGKSTLLKAISNAKPKIASYPFTTLKPNLGMAEFKDGRQISIADLPGLVEGSWANVGMGHKFLKHVERTKMLLFMVDINGFRLGPKYPYRSATENVVLLNKELELYSPDLVEKPSLLVVNKMDSPFAEDKLKRLLDELQHIRDVCARFPEEMCPDQFVVFDEIIPCSAKENKESVDYVKRRLRELLDFYDDQEREVQELAAKSRAKSKLIETNLQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQK0</accession>
    <name>A0A3R7PQK0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001233">
        <property type="protein sequence ID" value="ROT79513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQK0"/>
    <dbReference type="OrthoDB" id="6382356at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="412" mass="45176" checksum="E5463227FEB2039F" modified="2019-04-10" version="1">MSPSDYNEEEDELWSSDDDPDWLPEGGSEEDSHGDDEDELWSSDDDPDWVPEDHSNEDSSDEASQTSDKGKIGNLDQDLIQELAEAMLVSSGGRGTLEDMVGLVVSLELTREEALDALDGLYKMIAEQEQGREQGKEAHPNDVDQTRPEIPRPSPESESFSKRPLRQYKGQYSQQQQDEYRQADQLDLARGVEPLSPGSQGRVDVGDGVEPWRRRTTTATPSATGSGRAGGGLRTRLTLSPPPTLTYPSPLYPRLNLPSPPPLFLPLTPTLPRLTPLPPPYSHLPLTPTLPKIKLLSPTPHSPHPSPPLYPRLTPLPPPYSHLPLTPTLPKINSSPPPTLPHPHPHSTQDPPPYSPLPLTPTRLTPLPHPPTLPHPSPPLYPRLTPLPPPLLSLTPTLPKINSSPPPPHTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PU27</accession>
    <name>A0A3R7PU27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative nuclease HARBI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_024224</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HARBI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000797">
        <property type="protein sequence ID" value="ROT82609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PU27"/>
    <dbReference type="STRING" id="6689.A0A3R7PU27"/>
    <dbReference type="OrthoDB" id="6331085at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045249">
        <property type="entry name" value="HARBI1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027806">
        <property type="entry name" value="HARBI1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22930:SF289">
        <property type="entry name" value="DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13359">
        <property type="entry name" value="DDE_Tnp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE Tnp4" evidence="9">
        <location>
            <begin position="388"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT82609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="70470" checksum="7DCE89737336BE03" modified="2019-04-10" version="1">MYAGVVSVAQSDLSRLIKVAELLKIKGLAVPDEPAETRTSEDRTISRNKRTSPPGRSKTLPVTTDQVNSPSAKRRKTQESLTPLSTSRGSDAEWLKDCSRGEQNLDQSCIADEEGMDDSSPLQEALLPETQELHIKDEIIEITSCSDSNQDDTGLDFGTVTEDSKEPETLDDNCQDEVSMLIPKYESSGLDSQGAGPLITQPMFSDGLGGTMSGSSEIQAWFPDQEAASSVVMDGDNANTGDTNLQVAKMADSLADIEEINLIEEIIENIAALQPPRVALTERNNVFLSLNDEEFLARFRLSKDSAAVPSHIRLLITLRWMTTGGLQLAIADDFEVSQQFLSTCVKETLQSIASNFHRYVQFPDSQAIQAVSQQFQDIAGFPGVLGAIDCTHIPIESPGGERAEEFICKKGFFSLNVQGVCGPNLEFYNIVCRWPGSVHNSRIFANSDLCRKLEQGQYVGHLLGDSAYPLRPYLMTPVANPTREAELKYNTAHAKTSNIEMAFSLWKRRFRVLSSQLRSKLNTSMMAICSAAVLHNIAIKHKDTIPEGEDVDCEVDIRKDYSEREGICNLSTTEGLRKRASIINTVSPRTASCRNLLAPPLQLQHIKIRAFPRRRQLPPLSIAGRCYPGFREEPQVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWD3</accession>
    <name>A0A3R7PWD3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_022045</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000502">
        <property type="protein sequence ID" value="ROT84758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWD3"/>
    <dbReference type="OrthoDB" id="2157354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF4">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="666"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="724"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="377"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="14">
        <location>
            <begin position="566"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT84758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="915" mass="104322" checksum="AAC3DE0F549F5BF9" modified="2019-04-10" version="1">MASLPVSNTSSLLSHGFKPGDEEKLRNAVKSLPQKAINHVFPHPVYSPVLHVAVQNNSLELVQILLAAAADPNARDQRGKKFCPIHYATQNGNKEILEALLKAGADPNAKEGEFGRTSLHILATRWKTNEDDYKAFLDVLLSYKKIKIDSLDSNGSSPLYMAAMKSWEYMVRQMILKGANIESAVGNKTAGDIIRKKLPGLLETIDFSVIEKPKRFYGEELYDALKDGDVDLFREILQEVDNSDEVKYKASIIEEDHGEYTLLQYACDNGMQDFVEVLLKHGANPVRKDDTSKMSPIMYATRNGYYKIVEMLIDSMKSLRELEKGALKQCDQRKETPLHKAVKREYPENSEDVDYKKCLNLLLEKKRYLDIDAQDEFDNTPLHYAVLCDDQSFVRTLLLNGAHLGIRNKFGTLAITRIQASVLEEVLNDCIKYKNNVADRDFEIIMHYSMLAPAQASQQPETECLRFLSSSRKHRRLLLHPIIDTFLFLKWQRIRQYYFFNIFAYTAFLILLTAYVLIYFGTFIDPSEATPQNETEVASLNSPAEESIADQGMTVEKMKEALMENLVIKFLLKAVISIFALYIAVREGVQFCVSWRLYVSRLENWLEISIVVLTFVLLFLPLSAGPQQSLSAWLVLFSWIEFILLLGRHPYLAVYITMFTTVTYNFLKFIIMFSFMIVAFSISFYLVFQVDDNFKTYHQSLLKTIAMTTGEIEYTDLPLSTLPVSSHLLFVLFVFLIVLVLMNLLNGLAVSDIQQIQQEAEIVSYSSRVELISYIESVFLASPFQRILPGPITCCENGGDDCFLATCLDSSNPATKLLNWMGRRTLMFQSCLRERRITVYPNRGMDRWHVCDCHSFHLKEAQIEAAKDVVLEKEHSVSDHRLSSLEYRLDEVMAAISSLADKVNKHVLCPSPSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWR7</accession>
    <name>A0A3R7PWR7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative upstream stimulatory factor 2-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_001752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001232">
        <property type="protein sequence ID" value="ROT79521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWR7"/>
    <dbReference type="STRING" id="6689.A0A3R7PWR7"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11396">
        <property type="entry name" value="bHLHzip_USF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051732">
        <property type="entry name" value="USF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117:SF3">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="99"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="75"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="151"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT79521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="24254" checksum="2901ED70AB8F4BD4" modified="2019-04-10" version="1">MDMIQTALDTSGDKDCECEDDKVALTQRLAIVEEDGAVRDSSSPILAQSGFTLRSDSEHSGQFYVISDVLTNTAPRSLTPRTSESMMSQRLTGTTREEKRRVTHNEVERRRRDKINNWICRLAKIIPDCPDAHPKSAQSKGGILAKACDYISELRLQNEQLMERLKEVQRRDMDFELLKQEVEVLKNENAALKNENALVRSQLQQQGLLAELPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZF8</accession>
    <name>A0A3R7PZF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000897">
        <property type="protein sequence ID" value="ROT82008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZF8"/>
    <dbReference type="STRING" id="6689.A0A3R7PZF8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="525"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="605"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="648"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="683"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="721"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="747"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="776"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="802"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="845"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="877" mass="97661" checksum="E728B82E89FB6988" modified="2019-04-10" version="1">MGSHSEITISLFVGAFGGRRPVRVRVCLSVTFLRVSSSSSLPSSVLSLPVFCSFCLLCLLFFLFLASVLSLPVLLLLSLPVFCSFFPVFCSFSSSSVSFSSRLRVFFLPVFCSFSSVFSFSSRLLSSVLSLPSSVLFPSSVLSLPVFCSFSSRLLFFLFPSSVLSLPVFCLSLPVFCSFSSRLLFFLFPSSVLSLPVFVCLSLPVFCSFSSRLLSFSSRLFCSFSSRLRVSFSPVFCSFSSRLLSSLPVFSFSSRLLLFSSRLLFFLSSSFSFPSSCVFLFPSSVLSLPSSVLSLPVFCSFSSRLLFFLFPSSCVFLFPSSILSLPVFVCLSLPVFCSFSSRLLFFLFPSSVRLLFFLFRLLSSLPVFCSFSSVFVCLSLPVFCSCLRLLSFSSRLLFFLFPSSVLSLPVFCSFSSRLLFFSSFLSSSSSVLSLPVFVLSLPVFCSFLPVFCFFLFPSCLSLPVFCSFSSRPLFFLFPSSVLSLPVFCSFSSRLLFFLFPSSVLSLPVFCFSFPSSVLFSSRPLFFSSVFCLSLPVFCSFSSRLLCLLFFLFFCLSSVLSLSRLLFFLFPSSVLSLPVFCFFLFPSRLFLFSSVFSSSSVLSLPVFCPFSSVFCSFSSVLCSSLSPFFLFPSSVLSLPVFCSFSSRPLFFLFPSSVLSLPVFCSFSSRPLSFSSRLLFFLSRLLFLLFPSSVLSLPVFCSFSLLFFLFPSSVLSLPVFCPFSSRLLFFLFPSSVLSLPVFCSFSSRLLFFLSSVLSLPVFSVFFLFPLFFLFPSVLSLPASLWSSVLLASFFLVFCSFSSRLLFFLVLFFLFPSSVLSLPSSVLSLHFWSSVLSLPVFCSFSSRLLFFLFPSSVLSLPVFCSFSSRLLSLGNVYEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1K2</accession>
    <name>A0A3R7Q1K2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002985">
        <property type="protein sequence ID" value="ROT66155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1K2"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1K2"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF0">
        <property type="entry name" value="CID DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25985">
        <property type="entry name" value="Ubiquitin_USP47_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="757"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="792"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="834"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="847"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1032" mass="111595" checksum="2254D865D4065B1A" modified="2019-04-10" version="1">MFCFLRGVSSTPSDTPLDPFLETLRLRLLKVMMKQTESVEDGGGGDGGDGGGGGGEEKVSATASTQVTVDANATSVTTVTDNAEETSTKTTTSKFTKTTKVKTIKIVKKKNPNSLVANAIGQFNKKSEEEVSPPKKIVFKKSSESPKKVPGLPKKIIKTGENDSDTKTTDSPEAKDSSDSKKENGEKTPTSSRASAEKSSSESKEIPAKKEPSVKKESTEREASTPKTDAKDTTDKKEFSAKRDSTERKESPEKDSIEKKERVAKRESSERKETPEKKETGEKKESIAKRDSLERKETPEKKETVEKKESPVKRGSMERKASPAKRDSLEKKGTIEKNKSVEKRDTPESRESPLKKKSPLKKETPERKGSPARKTPPAKTEKEVTESKESSDVKAATTKEAEGKEDIATKEISKENAEATTIIDSPKETAPDSPKEEAQDKSESEDTKELAKTEASPEPEPSTRVKEPSSVIEITRASSSSSRSSKSPLSEYVEGAKAISAEASSGSVDKVLTSESDSCAEGASATPCSNDSKPRADSLLDSDSELSNVSVFVIVRDMSSLTARVNKETIVTPATSTCGELMQEVGRRFKYEPDSFSLILQCSNGDQVEIDKMEAERTLADARFQVEGTPRNNLILCDLGGHPPRRTDEDDLSLGASASPTASASEKKWFDRSSTYSNTPEYSYSAALIKHETEALEEMQIPPYKEEEPEPRPEVSSSGTSASATAEDAVSATSAASPASCSSKDSGISSKAATDCSSSEAGSSNNSSMVSPSSGPLSSLPTSAQPPSPGMSTSTQATTPTASPTATSAGNGSDGEDEGIADADSGAGSSNVNSDQSASEDSSLTSDSDRTLVGDPPEDKLSDTSNSPDYRNVSSPSSPEDNGRETKDDDNGWGLPIFQDTDVVWGDEDKETEVKRYFRAEYFTEDQTNQKMLRVFVDKRITIGQLKNEMQPWVGVSQDHFKLFKIYSNSRTLISKELAIHAVSDGFTVLDTPRDGHPPKIESPHRRRLRCWSHWVATCIPSFLILTRKFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q8P6</accession>
    <name>A0A3R7Q8P6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative vanin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_010295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q8P6"/>
    <dbReference type="STRING" id="6689.A0A3R7Q8P6"/>
    <dbReference type="OrthoDB" id="10250282at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040154">
        <property type="entry name" value="Biotinidase/VNN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043957">
        <property type="entry name" value="Vanin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609:SF14">
        <property type="entry name" value="BIOTINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10609">
        <property type="entry name" value="BIOTINIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19018">
        <property type="entry name" value="Vanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018638346" evidence="4">
        <location>
            <begin position="24"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="5">
        <location>
            <begin position="52"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT71419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="532" mass="58055" checksum="0D18348FEA8123CC" modified="2019-04-10" version="1">MVLRAGLLVAASVGLLLLQLARGERLRQESLVESLRASQTATHVRAGETVLYTGAVLEYEPYITWTEEGGEAILRENAKVIAEYAAAAKEMGADILVAPEYGLNGLDMHVLDPDELLSFTQNVPDPRDLVVPCSATSDLGQATAIKALSCSALENQMYLVIDVAEKTPCSEGDGSAPCPPSGSVLYNTQVVFDRNGTVIARYRKKNLFLEWQFTPGIESDDTALFTTDFGVTFTLQVCFDIAFGHPGLFNVDTRGVKDVAMSTAWVDVMPFLIAPSVQNGWSRGLGVNLLVSGHHRPERSKLGSGIFRGASDLEHDYVYDVESGSRLIVSEVQTVASVDGRRPLRRPSPSRGVAPPEARRGNRPSRRDHLIQYDDLSNYTQVVLQKGDSQAVQYAEACHDDGLCCHLTYTPAGNLTYSLLAYSGVVVQGFGTYQIYAQICAVVWCRSEDVATCGRLGEGLPGADAFPAFTIYADFAVDHVYPAMFTRDLALVENDLYDYSCDDQRSCTISTSAAVPELMTAGFYGRWYDRDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBV6</accession>
    <name>A0A3R7QBV6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003549">
        <property type="protein sequence ID" value="ROT62805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBV6"/>
    <dbReference type="STRING" id="6689.A0A3R7QBV6"/>
    <dbReference type="OrthoDB" id="6285196at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22903:SF8">
        <property type="entry name" value="MAX-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22903">
        <property type="entry name" value="PLEKHH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="524" mass="55924" checksum="62023D83EE88EA71" modified="2019-04-10" version="1">MVGSLPPFRSCVDSSRGSYEGDRPDSDESLHDGRNDVGTSRPDRRRSGGTDDPSPELALGIRASAALASPCCMALKAAMTQPLLGGCTPAAAAVRSPAGLRRASSSDTDANYGEIRFKSRHNGVPRSGGLDRKRYDDDKIRTRDSRVDSGSVDLETPQSLSPKSPLEVMLNSLTQSTGSLPRSGSRAGSRGESPRKPVPQPRTKHLKKGGSLQSSVTKSADSLDLELDGYDNTESTDSSQLARSGDSHLSDDGRRSRAKDEAHDYSEIYTPSRDHARWPGDAEANGEKPPTPPLHRFPSWESRIYQVAQEGLSGAGAATTADTSARMRTSGLGSYPEIHVPVYAAVKGVSSSGLPSSACQEQETRDLSEGPPRAPPPALVTATCAGATGPPLACDALTLNSLTVFLSAPLSTNNKFHHSRTEKKAKTYDTFLELNVRRHALPYRFAFCAVTPAGRDVPSRRADGKGRPSSAIAVEPPIAAAGRRRSSWVLAGLYSARHRWLTGNPPRAPPTRLADSIDSKKSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBX6</accession>
    <name>A0A3R7QBX6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase S1 and S6 chymotrypsin/Hap</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_019260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003531">
        <property type="protein sequence ID" value="ROT62869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBX6"/>
    <dbReference type="STRING" id="6689.A0A3R7QBX6"/>
    <dbReference type="OrthoDB" id="6336543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000122">
        <property type="entry name" value="Chymotrypsin-like elastase family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF54">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="120"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="355" mass="38077" checksum="C98E436810792F7C" modified="2019-04-10" version="1">MNPYGPLLSPLAPQQTIQNPLLLPSFLVSIRPTRTASPVLLSDDLRASVEANREAISELKSIVSKLLDCHSGCNLGHDDDGGLYAFRAPPVEIAPPPPGPSALHLAPTPEIVPPPPGPPGSMHLAATPGEFPWLVSLQVTNFEKVYVHLCGGTLIAPAWVLTAAHCLDSERIQELVVVLGEHDMDKEEGTEQKVTVKEVIKHPNYTHWNRPMDNDIALIHLSEAVKVREVVSFAELPSNVFEISTGLCREGGWGATDEGTPGPNVVKISEVPLLEKEKCKGAYNASLGDNVICAGEKGIGACVGDNGGPLMCHTPEGEVISGVMSWREGCALPGKPAVYMDVSKYIPWINHVMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCA9</accession>
    <name>A0A3R7QCA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hemocyte transglutaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_018982</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglutaminase superfamily. Transglutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003482">
        <property type="protein sequence ID" value="ROT63140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCA9"/>
    <dbReference type="OrthoDB" id="437511at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001102">
        <property type="entry name" value="Transglutaminase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00868">
        <property type="entry name" value="Transglut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglutaminase N-terminal" evidence="3">
        <location>
            <begin position="370"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="307"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT63140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="54158" checksum="41581AE17833DC62" modified="2019-04-10" version="1">MIFSSLLFLSLLWSLILPSLLSYLSSLIFLLFPFILLSSPISFFHFSPHIIVHYPSPRLSYIYPSPLVSRFLFPLFSTSTLSPFPPFFCSQDPQVPQDPQVPQDPQFLKTFRFLKTFQFLQTLRILKTLRFLQTLRFLQTLRFLQTLRILQTLRFLKTLRILQTLRFLKTLRFLKTFRFLQTLRFLKTFRILKTLRFLKTLRFLKTLRFLKTFRFLQTLRFLQTLRILQTLRFLQTLRFLQDPQVPPDPQVPPDPQDPPDPQDPPDPQDPPDPQVPQDPQDPPRPSGSQDPQVPQDPQVPPDPQVPQDPQVPSDPQVPQTLRFLKTPFVLSTRRLEDPKIVSVDFQPAYNAVNHHCEMYELVERPHRLPGPRPNVEKGTQGLLVVTGTKIEKTHDDWDVKLVKESGRKATIEVQIPTDAPVGVWKVAAEVTRRNQPGERHLRRFDTHVYILFNPWNERECVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCX5</accession>
    <name>A0A3R7QCX5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cytohesin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001849">
        <property type="protein sequence ID" value="ROT74767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCX5"/>
    <dbReference type="STRING" id="6689.A0A3R7QCX5"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01252">
        <property type="entry name" value="PH_GRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.20:FF:000003">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000309">
        <property type="entry name" value="Uncharacterized protein, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF402">
        <property type="entry name" value="MIP16918P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="48"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="253"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="44828" checksum="809B4FB3DB2325E7" modified="2019-04-10" version="1">MSRFRFGFLRIGFLGGFLGALVSRAAMRRGPVVAFLRVLESEAVGGAAVSKSNPKSKQMSIGRKKFNMDPKKGIEYLIDHGLLKNTPEDIAQFLHKGEGLNKTAIGDYLGERNDFNQSVLDAFVCLHDFTDLILVQALRQFLWSFRLPGEAQKIDRMMERFAHRYCELNPAIFKNPDTCFVLSFAIIMLNTSLHNPAVKDKQTIEQFIAMNRGIDNGDDLPRELLESLYESIKTEPFKIPEDDGNDLMHTFFNPDREGWLMKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENIEVREVQDRNKPNCFELYATSTDFIKACKTDSEGKVVEGKHTVYRMSAATPEEKEEWIKCIRQSISHNPFYDMLAKRKKNIQKNSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE60</accession>
    <name>A0A3R7QE60_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative forkhead box protein A4-A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005555</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001719">
        <property type="protein sequence ID" value="ROT75878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE60"/>
    <dbReference type="STRING" id="6689.A0A3R7QE60"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001710">
        <property type="term" value="P:mesodermal cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000071">
        <property type="entry name" value="Forkhead box F1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051770">
        <property type="entry name" value="Forkhead_box_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46262">
        <property type="entry name" value="FORKHEAD BOX PROTEIN BINIOU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46262:SF2">
        <property type="entry name" value="FORKHEAD BOX PROTEIN BINIOU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="6">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="4">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="192"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="233" mass="26022" checksum="48823524D3135455" modified="2019-04-10" version="1">MAIQSSPQRRLTLSEIYQFLQQRFAFFRGTYTGWKNSVRHNLSLNECFIKLPKSMGRPGKGHYWAIDPTAELMFEEGSFRRRPRGFRRKVQAMKPYPLYQSAAPSLPPPYDVCSSQLPPATQYAQYPSYQEYPAYPQPPTSYGSNMYAASCSLTYSGGGAVGEYQPGSPGVYTSMAPAAPLPPMGALPDRDMWSALTPNTTPTLTPTTGYVKQSNSPTGKGRRRDGRRIPLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFN7</accession>
    <name>A0A3R7QFN7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003012">
        <property type="protein sequence ID" value="ROT65956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFN7"/>
    <dbReference type="OrthoDB" id="6427659at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="155" mass="17069" checksum="DF5BD743E0184BE8" modified="2019-04-10" version="1">MSTGLPHSCFESPHRNPWVTEKDGDSRTSSAAQLAQTDALTDKHKTQTHNYVSAFQPLSSQICQTSVSLTTTVTPASSWVEPKLLRNAPVHPERSGFAGSVFIAGGRNEITCPGIQSNICNHHQAQQHSFQQSQPGFLFRPHVSMKITPQEDYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGF0</accession>
    <name>A0A3R7QGF0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_015388</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGF0"/>
    <dbReference type="OrthoDB" id="6332316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="16">
        <location>
            <begin position="68"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT66589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="42360" checksum="43A279059455158E" modified="2019-04-10" version="1">MSWNNQEMEDNPIPSTNPYGNYTVVDTAAKEILHMVHEHWYQFPPMNPLWYSLVGFWIVVMGSLSLAGNFVVIWVFMNTKSLRTPANLLVVNLALSDFLMMFTMFPPMVVSCYWQTWTLGALFCEIYGFLGSLFGCVSIWTMVWITADRYNVIVKGVSAEPLTSGGSMLRIAGTWVASIAWCLPPFFGWNRYVPEGNLTACGTDYLTETQLSKSYLYVYSIWVYLFPLAYIIYSYTFIVKAVAAHEKAMREQAKKMGVKSLRNEENQKTSAECRLAKVALMTVTLWFMAWTPYFIINWGGMFNKPMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLVCTGEGDKASEVGSVSTVETSEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJF2</accession>
    <name>A0A3R7QJF2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative general transcription factor II-I repeat domain-containing protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_012376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002565">
        <property type="protein sequence ID" value="ROT69412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJF2"/>
    <dbReference type="OrthoDB" id="6356674at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45913:SF21">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45913">
        <property type="entry name" value="EPM2A-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT69412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="293" mass="32974" checksum="0A090341C3EFBA3F" modified="2019-04-10" version="1">MCEELAALQSLKGTTTGEDIFGKVYQTMEELDLDWSKLASITTDGASSMVGMSRGPLPNSPASTVLQSVDVGFCHEDMTEMLNSFNLQLQGQGKLICDIYSHTKAFEVKLELLLGQVKKHSFIHLPATQNLSAENPAVSFPAEKCVEALEMLKAEFGVRFRELHVYAKEIHLFQNPFVADIDEAQPSYQFELAELQDCDVLKDAFKPNSLIDFYAALPNDTYPNIRKHAMKMSTLFGSTYICEQTFSRMKLLKTPMRSRLTDEHLHQCLRLAVTKMEPDIQLLTSQMQAHSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QM41</accession>
    <name>A0A3R7QM41_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023373</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000685">
        <property type="protein sequence ID" value="ROT83439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QM41"/>
    <dbReference type="STRING" id="6689.A0A3R7QM41"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46735:SF3">
        <property type="entry name" value="CALPAIN SMALL SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46735">
        <property type="entry name" value="CALPAIN, SMALL SUBUNIT 1 A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="181"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT83439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="283" mass="31452" checksum="93492D0EB2831CF1" modified="2019-04-10" version="1" fragment="single">MWEVVTFDGAWVRNATAGGGDRKHRVFCSNPQYILELTEADDGAEGTCATISKKKRNTNPLTVSWLRLNVPISHEDLLQGEDCDPPPCLTRQYLVIPAHPSQTKRRSSFCGCSVRSSSDGGVRRGAQILDIAYESEDEVDHSIEDHLRAVFREAAGEANDVDAVKLQAMLEQLFPSAGFADSLDFTRSFLAMMDLDFSGTVNFYEFEALFSSLSRWWVYNSRKDEESGLLSGHSWGLGDALRDLGLQIPRRIRALVVVRYGDQQGHVAQDFLMAPAGSPSCWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMF7</accession>
    <name>A0A3R7QMF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000633">
        <property type="protein sequence ID" value="ROT83772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMF7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="677"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="773"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="790"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="844"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="893" mass="94742" checksum="3B42C5587A61F104" modified="2019-04-10" version="1">MQFVRVCLFVCCAKDPPPPPDGTHRPLRTTGPNGDPPPPPDDGTHRPLRTGDDPPRRDPPPPLTTPPPDDGTHRDPTASGRRWTPPPPPDDGTPAPSGRRDPPPPPDGSRRDLPPPSRRRFSPTAPPDEGTHRPLRTSGRPPDDGTHRPSRPHRPSDDGTHRPLPTGPRPLHRPPDDGIHTTHRDPHPTGPSDDLTDPTTGPTAPPDDSSSSSRTTGPTPPSTGSGRGDPPPPPDSGLPDDGTTAPSRRDPRPSGSDDGTHPPLPTGPTAPSGQTTPPDDGPTAPSGRRDPPPPPMTPPPLQTTGPTAPSGRRDHRPLLPPPDDGPTAPTRTHRPLRTGPTAPSGRRDPPPPPRRDPPPPPDDGTHRPPPDDGTHRPSGRRGPTAPSDEDPPPPPTTPDDPHRPSEPTPLQTTGPTAPSGRRDHRPLRRRGPPPPRRRDHPPPPDRDPPPPPDDGTHRPLRTTGPTAPPDEGTHRPLRTTGPTAPSTTGPTAPSPPNDGPTAPSGRRDHRPLRTRTTAPSGRRDPPPPPTTGPPPPPDDGTHRPLRNEGSGRRTTAPSGRRDPPPLRTTGPTAPSGRRDPPPSRRRDPPPLRTTGTHRPLRTRGPTASSGRRDHRPSGRRDPPPPPDDGTHRPLRTTGPTAPPDRLLPRPPPPDEPPPPPDEGPTAPSGRRDHRPLRTTGTHAPPTTGPTAPSGRRGPTAPPDDGTHRPSGRRGTHRPLRTRGPTAPSGRDPPPLRTGPTAPSDTDPPPPPDGTDPPPPPHRPLPDDGTTAPRTRDHRPSDDGGPHRPLRTTGPTAPLRTTGPPPPPDRPHRPLRGPRPSGRGSTALQTGTHRPLQTGPTSPREPARVGEHNERDEAVHEVEEVDHPVLPVQDVEEGEREGRDDAGGHAVGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPA7</accession>
    <name>A0A3R7QPA7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase 4 regulatory subunit 1-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001999">
        <property type="protein sequence ID" value="ROT73728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPA7"/>
    <dbReference type="STRING" id="6689.A0A3R7QPA7"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20595" checksum="6821A0832C90DAA7" modified="2019-04-10" version="1">MNSLSSNDGVGEAVSDTAVSWDLLEEAAVRTELMEQVPQIAVLCHEYPEHLGGVVANNLVPMVVKYLTDPNNQVRKTSQAALLVLLEQELVSRSDVHDQVCPVILDLTCPDAMDDFKTEAVALMSKMAPLIGREMTERLFLERFTRLCSDALFQVRKVCASNFGDFCSVVGTQPTEEVLVSTRAHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QQ23</accession>
    <name>A0A3R7QQ23_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001910">
        <property type="protein sequence ID" value="ROT74322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QQ23"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="548" mass="59733" checksum="D4E2DB8A050E99BE" modified="2019-04-10" version="1">MPTKPIITSSNYKRAIKAHKHILFSPSFRSSPNLYPRRHGREGGREYRIAIYNPEVLHRPTFLYLIQRVLVSDPFARLSPASIPFRLVIAAESQGKRARHRRDVAKGRDTEGCGVELPCGRCRDVVMGPSPFSLSLFLSPPPSSLPCPLINLPRSPTPSLAPSLLSYLPFPISSLSLTLLSSFPSISSLPLHLLSTHPPSPLLFPPSYHPPFPPSYLPPPPLLPLFPIPLATYHFLPLPPSFPISPSPSPPTPIHPSYLPRRLPPSIPLFPSPSPPIPSTSLSLSLSPSPSPLSPLLSPRHPNPPSPFPHLPRSPPSPWPPPSDLPLAALPPFTLLSPLLSRPSPSLPLPPSPRHPTTLQPSPIFPRRPTTLLPLSPSPSLPTPLSLSMFPRSPLPPFPFLSPSLPLPLLFPFLSPRALHPPFPFPSPSPPIPSFPSYPRRPTPPFPLPISLAAYHPLFPIPHLPRRPTLPPPFSSLSPSPPTPSLPLSHLPRPTPFTLLSLSLSLPPLPLPSPFPISSPPLPPLCSSLIFPRPYPLSPRRPEGVFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWI3</accession>
    <name>A0A3R7SWI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger protein 85-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_002638</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001348">
        <property type="protein sequence ID" value="ROT78667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWI3"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24393:SF143">
        <property type="entry name" value="ENDOTHELIAL ZINC FINGER PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24393">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="62"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT78667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="280" mass="32326" checksum="C68235E6C9EA73A9" modified="2019-04-10" version="1">MLCKDRPYKCDQCTASFIDPGELSEHKKKHSGDGPFTCEDCHFTFMYKSHFRSHKTRCQKKRAMMPHPPKPIANNRSNTKNNSHNNRQQNANNTVPFNPSNPTFKRQKKEQRQDRPFECHECDASFQTLQDLQSHKAKHTGEGPFKCEECRFVFLYRKLYEAHRRRCEKKRKEPQLAIQSGRTVSTVPSSVSSVQLAGPIFQHQPTVIDMRAVQPQQQVQQVQHIQHPAIIEQVIHVTQVPTSMGGGRQEIKYDLVPATVDMENVNQIMNLIKVKGQPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S911</accession>
    <name>A0A423S911_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004609">
        <property type="protein sequence ID" value="ROT60714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S911"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="652"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="715"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="744"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="928" mass="100985" checksum="752374200CB114F5" modified="2019-05-08" version="1">MIRQDVALRSYVGLCTLQDTRAPPLRQSQPQPAESVALPLTARDYPTRLVLTLVNTQTQQLVALRTPESAVVDLSRGGIVVTNRLRGNHKASFKGKNPWRRGDNSRHPARRPLGHCLQIDLITPSLSSPPPLLPLFVSFGLIRKKVPMVSSLLLLLLLLAPSRLSSFSPSFEGQRGRGAGRGAAWAAAVEPLDAIDWAPRRALGVAVGGALGGAVGGAVGAGEASLTFEEMREGRVVTFFEILHISTIKIDTSPPPTPASLFFSRLFFLSLSLLPLLPPPHPPRLLSLYFLSSPFPAIYPLRATPSSLSSPPLPLSPPPPVPLLHFIPPPPLAPPSSLFPLPPPFPPSPFPSPLPPLRLSLPRSLSPLPPSLSLSSPPPLPSSLPLPSSPLPLSSSPSSPFLSLTSTLPPSLLFPILPSPPSFPPSLLFSLPPYFPKYSPPYLSSSLIPLFFYPPSTFPPPSPISLSFFFYPLLLSPFLFLSPPSPSSIPPHLFLSPLPPFFYLSPPSISPFLLLSPPPSLLLYFSPPSISPSLLPSLLPFYLLPSPTSIFPLPHFYPLSLFYLPSPHFLSSFFHPPPPLLSPHFFSPSPPPPHTHFQSDPNKSESVSETRRIFLSLLFFYFSDFYFLYLHLLPPPSFSPFIYFSSFCPPPPFLSLLLPSLSPILPFSLSFSTFSYFLFPFPLLSSLSSFIPPFSPFLSSSPTYPSLPPTFHLPPFLSLFLFLTSFSPFSLPSLFLFYPFLPPFSLLLLLTLSSSYLPSSSLSLSFPNFSLPSPPSSLSPTYPLSSSYLPSPPFSSLPPHLSLPSPSPFSPPFFSSSPTYPSLPSNPSPPFLFFSFLLLPHLSLPFSLPFSPPLLSSSPTFLPPFSLYLTYPSLPSYLPSLPLLSSPPPSSYPSPPPPSLFSSPISLFHLSSSISLPFSLFSTYPLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S969</accession>
    <name>A0A423S969_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TATA-box-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">TATA sequence-binding protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">TATA-binding factor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">TATA-box factor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Transcription initiation factor TFIID TBP subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_021617</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004559">
        <property type="protein sequence ID" value="ROT60780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S969"/>
    <dbReference type="STRING" id="6689.A0A423S969"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000992">
        <property type="term" value="F:RNA polymerase III cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001092">
        <property type="term" value="F:TFIIA-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT60780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="202" mass="21926" checksum="9E1B7032CEBD370F" modified="2019-05-08" version="1" fragment="single">MQPQTPSMMSPAVGGGSQVGAGMFGSATGPSTPIGGPMTPMTPHSADPGIVPQLQNIVSTVNLSCKLELKKIALHARNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEQDSRLAARKYARIVQKLGFPAKFMDFKIQNMVGSCDVKFPIRLEGLVLTHSQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SB68</accession>
    <name>A0A423SB68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative extensin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004194">
        <property type="protein sequence ID" value="ROT61403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SB68"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="536" mass="57969" checksum="4F2B0AD81DA626BB" modified="2019-05-08" version="1">MVICLYTFPVPSPHGRPVTHPQSVASHTPPIGRQVTHTQSFAGHTHPIVRRSHTPNRSPVTHTQSFASHTHPIGRQSHTPKSVASHTTPNRSPVHTPIVAVTPTQSVASHTQSRQSHPPIGSHTPIGRSHPPSVASSHPPSVAIGHTHPIGRQSHTHPNRSPVTHPIGRQSHTPNRRQSHTPSSQSPPNRSPVTPQSVASHTPNRSQSHQSVASHTPTSPVTHPNRSPVTHPNRSPVHTPPIGRQSHTANRSPVTPPQSVASHTPQSVAFTHPIGRQSHTPIGRQSTHPNRSPVTHPQSVASHTPQSVASHTHPIGRQSHTPIVASHTPPIGRQSHPIGRQSHIRNRSPVTHTQSSPVTHTPIGRQSQTPNRSPVTTPIGRQSHTPIVASHTHPIGRQSHTPSRQSHTPKSHSQSHTPIVGRQSHTPTVTPNQSHTAKSVASHTPPIGRQSHTQSIGRQSHTPIGRQSHTPIGRHHQWRQFTPITHPSHTPNYGRQSHTPSVASHTPQSVASHTPNRSPVTHPNRSPVTTTIARHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCC5</accession>
    <name>A0A423SCC5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003969">
        <property type="protein sequence ID" value="ROT61867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCC5"/>
    <dbReference type="STRING" id="6689.A0A423SCC5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="60683" checksum="94988BA6DFB9E6AA" modified="2019-05-08" version="1">MPMTDGGMRQVSCAKRSFIPNPLPPLLPPPPFPFSTALPPSYLCYPPPLPSFAPAALLPPFITASLRPLLYSYFPLFLSPMSISPTLLYSLLFSLSVFLLLFHALFPHPFCGPSPIPSPLFPPTFLPFNLPLYPFLSPVLPSFPIPLPLLFYPFHSSTSSHVPLTPLLLLSSEVLSFLLLYPSPFNIFPSPIRLPPPSFSFFPYLLPPPSSSSSPALFLSPLPTSLPSSLSPTPSPPFSCPPPHSPLSPTPLPPLLLCPPSPLTLFPYPTAPTPPPPLPPPPHSPFPLPHFPPFSCPPPTHPFPYPTSPLLPPLPHSFPPLPPHPLTPFPLPPPLPLTPSSLSPTLFPPSLPTPHSPLSSALLLPPLPHAPHSPLPPHPLTPFPCFARSFQLSCFARRPKCNDSLPGWCAFPYYARPALLVGGPSPCLPMPPSPSVISNHVRSRRGPPLCFYRLCWRDLRQFGGFRHLARLRVGLWDEGASSFKRHHRSPPSHGKLRERPLPAVPLRAAPSYAEESLARCSFVRPRVASDHPATRPLDKRFASQQTFVTDGRLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCC8</accession>
    <name>A0A423SCC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003971">
        <property type="protein sequence ID" value="ROT61846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCC8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="55526" checksum="8A8FEAA1D167F98A" modified="2019-05-08" version="1">MMQLKLLGSEAHSTITRCGRSTHARVACSTMPVVVGALPSARCAVLYHARCGALSTMPACWSLYHARCWCSTLPVVVLLLTMPLSGLTMPVWAPTMPLWVLLPARCGVLYHAPLLCGALPWPVVGLLPMPVVGALPCPLWALYHARCGALPVVGAYHARWGRFYHARLCASTMPVVFAHHCPLWGATYRMPCGRSTMPVCGPLWGSTMPVVVLYHARFVCSTIARCGPLLPCPLWVRLHALVGALHARCGASLPCPLWALYHAACSTMPRCVLYPCPLWVLYHAPLWVFSTMPVVRVLLTNALVWLYHCRCGVLYQCPLWVLLTMPVVGLLLPCPLWVLYHARLYHPVVGALTMPLWLFYHARCGCSTMPFVGALPCPLWVCSTMPLWVLIPVVVALPARCVAAPPCPLCALYHARCGRSTMPVVCAPPCPVCALPALPARCGALPCLLWALYHARCVRSTMPVVGALPYPLWVLHHARCGCSTMPVVGALPCPLWVLYHVVGALPCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIG9</accession>
    <name>A0A423SIG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003350">
        <property type="protein sequence ID" value="ROT63954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIG9"/>
    <dbReference type="STRING" id="6689.A0A423SIG9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="592"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="621" mass="64753" checksum="F8636FA13C7BD5C9" modified="2019-05-08" version="1">MAGCWGSFLSRLRVRRTQGRETTASPDQNNGRGELPPGREPFSLSPSRGCQGSGAQAPFQPASHVGSAGGGAWDCRGGFPFSPQGCAHPGSNSALPAKRGRGEKNRRGLSRREGKAAKGGRHSETIPNVKRGAVACVKGRTTADTGGGGTGTGYPGGPRSALWREPATFAREIRGRDRRPSLPRAQDGAQTPKRHHTPPDVRTGRKEQSSKGQKGKQQGERRNGEGGKRCGHGCPPIVVGAVPQPTRPQTGPPPAPRPGRGRPPHAPPPTPRAACSGRLRTRGGPAPALPRSSPAQHARQGPTRPRGRGRSAPGPGKAAPPTAPAARPPQSLPRFRGREPERQGLPHGGGGHARCRLRPRPERAQGAGEPKPPARGLSARALSQHDRKQGPLLRHAQGEDALRTPHHPRPGKRLTFSRGGLLGPAPDPRGTRARLAAFQPSPARSAGGGRGPRVDHPVVVGAGRLSPHDRGAGALSARALSQHDRKQGPLLRHAQGEDALRTPHHPRPGKRLTFSRGGLLGPAPDPRGTRARLAAFQPSPARSAGAHTTAGQGPFGPRGQGRQPLRRPRQPGLPQSLPAFGDGSRRGRGFLTAAGGTPAAASAPGPRGRRGQESPSRPPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKU4</accession>
    <name>A0A423SKU4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003176">
        <property type="protein sequence ID" value="ROT64846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKU4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="48062" checksum="51546235C3977DAA" modified="2019-05-08" version="1">MERTWSNFMRLRKCVTHLKHLAMLHPLQTLLWQPYLQVPWKRFLSNICLITEYAAYHNRNLRPPWSLEAGSLVLYKIKTTQTGPDRALGPRWQGPAKVVKKLSPPFSERNCHANQLRPFKLEEELTFPDASPYHDPDYVDPWLPDDAEPDHSNTSTSCGLSSETDVARTTNSARPYLELPECPGPPLLYLSTVRVPLDLSAQHSQQPPFDVMAASLRSAHARRPVGLAREAFTSGSGAGCAKRGTSGSGAGCATRGTSGAARGNRGTSGSGAGARVRADTPSGAGCATVVRGSGAGATRYERERGNLRGAGCATYGTNGSGARQIGSGSAIRGGLLEGKNCIPFRCLGFVGLQDRRVEVSTRTSAAGSSREKILRDVKASIGSPSSTPTDIISQPKPSDFPSTSYIRTRVFVGADVNPQIRKPGYKTTAFTGVSIPHSGPFSHEFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SL47</accession>
    <name>A0A423SL47_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-1,4-mannosyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">GDP-mannose-dolichol diphosphochitobiose mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_017074</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13865"/>
            <dbReference type="Rhea" id="RHEA-COMP:19510"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57269"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="EC" id="2.4.1.142"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13866"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003160">
        <property type="protein sequence ID" value="ROT64967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SL47"/>
    <dbReference type="STRING" id="6689.A0A423SL47"/>
    <dbReference type="OrthoDB" id="614844at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004578">
        <property type="term" value="F:chitobiosyldiphosphodolichol beta-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026051">
        <property type="entry name" value="ALG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036">
        <property type="entry name" value="BETA1,4 MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13036:SF0">
        <property type="entry name" value="CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="14">
        <location>
            <begin position="284"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT64967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="449" mass="51575" checksum="EBAEF25C02B7FAB7" modified="2019-05-08" version="1">MGYQRDKKREQVTLVVLGDLGHSPRMNYHALSLSEEGFEVNLVGFAGSKPQIEVLKDEHITLTYMRPSPAAFGNLPRVLAYFMKVLWQAIILFFTLLTSPRSKVLLMQNPPGIPTMPVCWFFCIITRTKFLIDWHNYGYTIMAINLRQNHPLVFVYSLCERIFGKQAHGGLCVTKAMKINLAQKWGIQKVTVLYDRPADRFHPISLEEKHNLFMKLSTTYSCFSGSSPDKTVFTERYADGRVIECEDRPALLVSSTSWTEDEDFSILFHALEDYEGVRHEFPDHYPPLIVVVTGKGPMKEYYTSLVAERMWMHVAVITPWMTAEDYPTLLAAADLGVCLHYSSSGLDLPMKVVDMFGSRLPVAAIDYPALPELVKHNENGLIFKNKEELANLLQDWFRGFPRETAIKETYYDFYKNLDEFRKLKWHPCWTCNALPLFLDGVSGQQRLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNY1</accession>
    <name>A0A423SNY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016147</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003021">
        <property type="protein sequence ID" value="ROT65869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNY1"/>
    <dbReference type="OrthoDB" id="6084525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030165">
        <property type="term" value="F:PDZ domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011646">
        <property type="entry name" value="KAP_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052771">
        <property type="entry name" value="Neurotrophin_sig_adaptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057092">
        <property type="entry name" value="SAM_KIDINS220"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24116">
        <property type="entry name" value="KINASE D-INTERACTING SUBSTRATE OF 220 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24116:SF0">
        <property type="entry name" value="KINASE D-INTERACTING SUBSTRATE OF 220 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07693">
        <property type="entry name" value="KAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23307">
        <property type="entry name" value="SAM_KIDINS220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="601"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="98"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="KAP NTPase" evidence="4">
        <location>
            <begin position="303"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="Kinase D-interacting substrate of 220 kDa-like SAM" evidence="5">
        <location>
            <begin position="1067"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="562"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="770"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1229"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="779"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="792"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1237"/>
            <end position="1251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1251" mass="140259" checksum="868EE3C01F75332A" modified="2019-05-08" version="1">MSSLVWASGRGHTAIVRELLIHGAKVNIGDKFGTTPLIWACRKGYYEIAEELLKHGASVDASGMYSWTPLLVATKGNYVDLVNLLLEHRPNLNALDKEGGTALTIACKEGYTEIATALLNAGAYVNVQDRNCDSNLIQAARGGHKAVVEALLKKYADVDMVGKERKTALYWAVEKGHTSVVKVLLSANPDLEHTTKDGDTALLRAVRTKNAEVVQLLVDKRARVSVADKKGDTALHIAMRGRSKRIVEILLRNPKNSQLLYRPNRSGETPYNIDLSNQKTILGQIFGARRLNTNEDNENMLGYDLYSSSMADILSEPSLSMPISVGLYAKWGSGKSFLIRKLKEEMCSFARQWVEPLFQFSPLVVLVVVHLSLLVGLIAAVPTISWEIGLAAGGSVFLVITLFLVAVWHGSRRYDWHLWYRWSVALAHQVAAFKLVLQVIFCSPPGPQWKEWKDGVQARPLKFIFAEGAKPSSTAGGENSVVQMLGSLFDMVEKEYGMFATRFYRAFRPKPQGVSAPWKYRRLCCMPYIVIFFVTLFCLVTVFVIGGLFGFHEQTYDNTTESSISKRDLTEDEDDDASGESSEEAPYVDTRPYHGALMNPLLITLGVLAAVVVVANLHTLARMFGSLIFSHRRHLIRRVAKLDTIKAEGYLQTLKSEVNLMVEMVKCLDAFTAQQTRLVIVVDGLDSCEQEKAIELHVHRVFNESSISGHDYLRNIVHLPFYLQNSGLRKVKQAQQAAEKTRGRSQSMWLEVETDSVSIATTSAMGGISHIPANRRMSSESGLSSSQNLRRNNSKSSRRTLRPSDSVASSIGSNLNRVGGAQDLTKVLLTDDYFSDINPRSMRRLMNVVYITGRLLKAFHIDFNWYHLASWINITEQWPYRASWLILFYEANEDTLDDKCSLKDLFEKIKNQVPNSKEVEPLLEMDKEEKKFEIFLSMHKSSLHVSDLKVFLPFTINLDPFIRKVIKEDQPQFDDMGPQFTANPTSPWSFQQYDPQSKVTTTPRRPVRGNQKNSTATMPPMNPLMWGYGPPFLPSIQSAPSVDFNPVPMNMNTASNTASLPPEAADKKLSSLSIEGLFEIFSKVEGVSTGILPAYKERFIEHNINGKVLLHCDLDDLKKVLHMNFGDWELFRVLVLGLREREADEEFIAKNVRFADTHIQRNNSQDLEDNAAPSSLLSSSSGEGSLMRRGSSRASSTMSSNKDREDLHGSVRKVTKQNLLAKQASLNEAYQASDTEEDHHFTPVKEKQLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQT8</accession>
    <name>A0A423SQT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_015357</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQT8"/>
    <dbReference type="OrthoDB" id="6332316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="5" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 15 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="18">
        <location>
            <begin position="68"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT66558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="350" mass="39092" checksum="4E9E1863615FF07D" modified="2019-05-08" version="1">MSSWNSPVQDTVLPTTNPYGNYTVVDTVPESMLHMVHSHWYQFPPMNPLWYGLLGFWMTVMGTLSVAGNFVVIWVFMNTKSLRTPANLLVVNLAISDFFMMVTMTPPLLVNAYWGTWVLGAFFCEIYAFFGSFFGCVSIWSMVFITADRYNVIVKGVSAEPLTSGGAMLRIAGTWAFTLAWCLPPFFGWNRYVPEGNMLACGTDYLTETELSRSYLYVYSKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFVAWTPYFVINWGGMFNKPIVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACATEGRDGGSDAGSTTTAETSEKTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRF6</accession>
    <name>A0A423SRF6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002887">
        <property type="protein sequence ID" value="ROT66781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRF6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="609" mass="65665" checksum="924D1E59CB5C9BD8" modified="2019-05-08" version="1">MAATAAWEGTGRPPTDELQTPPGRSAQPPQGASAGTTPTLLHDSAQSTAKDSPATGKKDVRSTVRVTVNLPVSTPTGTKLAVTTRSESPAGGEGLKVEPKNLDQEKEIALSQLQELEEAIKVRKVSKVDGRKIRWIEYRARKKQEEQEKAAEAKKKGRRSKVRSLTKGLREVRKVENGESPKKADDRTPIPASSPITPVSIPTSTPVLSQPKTEPGTKCPLIAVAARLLSPPSARSKSLDNARSRKANTRGGAKKPSGKAAERSESEPRSIMNGHTLVQNGPSEEEESISFNVSSSDAEDKCAEVIEEKTETNVELQSYQNTEVTVDEKATDENLDVSVKEEEIEPKSADSTVDGELPDLDNSYESDTPNRRGRGRPPKRKYGLLYVERRLRLQRKLKKGTVLPGGTDNEDTKDSSPASKIQARLSDDSTEGSSQAKDLAPTPSVTDAKKSKSSAGKKQTVSIVGEEKEDDNTSASMSNQTPQLQESIQSTKLVKGVQKVINQEVPSEAESATATASNNDSKSASSVKESGNIVEVHTKRENDTGDVADGQKEKEGLGVSESENLTEKESCKNKSEIPVEKAKKVSKTQMKKGGSVPKLVFRDQVFKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STP7</accession>
    <name>A0A423STP7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C-type lectin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002787">
        <property type="protein sequence ID" value="ROT67612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STP7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019478372" evidence="1">
        <location>
            <begin position="18"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="20379" checksum="8FA310A944A7EF08" modified="2019-05-08" version="1">MRVVAAFVWAVAGAAWALEEGGVGSLYDQYFPPLHPNCAQSLTDLLLRQESQLRESAGILKEILSETKGSLATEASCSGTFRKFGGTCLYIAKDVKKTWDAARTFCQDLGGDLAVFRDANALAEAIEYAKALGESFSSTVHVLLFIHVLINTFFISFEDDNGCYVMVARATGILYQYFYATLKICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SX69</accession>
    <name>A0A423SX69_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sec1 family domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002627">
        <property type="protein sequence ID" value="ROT68850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SX69"/>
    <dbReference type="STRING" id="6689.A0A423SX69"/>
    <dbReference type="OrthoDB" id="549905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="73485" checksum="68D77BB7BFCCB4B7" modified="2019-05-08" version="1">MQFASAVHVSEAWWAEACKKVKNAVVFVDNASAECLHWNGGLARLVDAGAKNVKEFSSFECGNKGDVKAVFMLGTAVVDITAKILQDIIHSSNFEYCVVITAGHPNVHAYARYGGRETDEGVLMNQLEQTILGWMGNMNYTVEIFYIPLVVVPYSESLFFMPPFADLYPLLNTDVARLAKLQQAQTKGERVKLVESLADVEFHHLPFEMRIMIRQFVVCIHSLMQGMNARDEIFSVGHTARIIGSELDSFGPARQRRKNAANKVSIVLVDRTLDLAAASIFSSDTLMERILCLLPRLFGHHLDSAVSMAPLCQVHSSSEWTLIPGCLAPQGNEKKAKEVLSALVLSSRKEALGLLNKHVLQAANRKEAGSGEIDKEGKMTIGNLKKNIQTFASDVEAFSEHASLLQQGLGVVEALSDERHEHLDQLLSLQKLLLQSIGDPEETPPFTQILQLLKTRGTHGVSLDDVLTLMVYATSLGGSSVFSQRDEYALTNLLSQAIVEDKLDLSDTLLEIIGEDVDEVSALKASQNIASQLHAIATARDHLKNYKNLHIPGDAAQPASCQGLLQKLVHDSLTAPQTEISDIEYRSAGFKDLIKTGFSLFVNVSKPMPRDAPAIIVYVIGGVTAGEVREIKQRVEEVGPPCEVLLASSHLAHPSDTIARALKPSPFIQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY66</accession>
    <name>A0A423SY66_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_012853</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT68998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY66"/>
    <dbReference type="STRING" id="6689.A0A423SY66"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000173">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone H2A C-terminal" evidence="15">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT68998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13749" checksum="51608C27B6538AD2" modified="2019-05-08" version="1">MSGRGKGGKVKGKSKSRSSRAGLQFPVRRIHRLLRSGERATMLNCWPLCTSLPLWSIWLLKSSSWQVMPRDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1Q0</accession>
    <name>A0A423T1Q0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LolA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_011312</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002431">
        <property type="protein sequence ID" value="ROT70407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1Q0"/>
    <dbReference type="OrthoDB" id="6345442at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058831">
        <property type="entry name" value="LolA-like_dom_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36902:SF1">
        <property type="entry name" value="ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25898">
        <property type="entry name" value="LolA_2nd_metazoa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019031509" description="LolA-like domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="732"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="LolA-like" evidence="4">
        <location>
            <begin position="260"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="656"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="769" mass="86076" checksum="A2DC08EA4D09779A" modified="2019-05-08" version="1">MVRMVAAIVTVLATVDASQRKTQYCDVIPDALDPPPHPEVTNQYTCAMEVVSDAPENPGDPNMRLEMFVKEVYDEPGNMFSMQIASKYYVERYILNWNTKQMLFIHTSKNSNEVRECVPRPLSEGVIFFPPILGSGQNLSVSHIVGPGAVLGILNWNETHYKGEYSFRGMTADRWDWCGLKEFENETGSHNISMATYWSSSKWSMPVMPTAEASIPLGWEVEVHEPQGGGSHGYYTVETLVHNIMDFSPGVVDYEEFRIPEGLFCEGMVPLEGHPFPDFSKDRLFTFSMEMRDSRVKDFTWADGWYDFEKQLYRIDHEIMSTPRERITATEVFDFNDGLAFTFGKKIARCRITIVNDTRTDWSDITGIGHLWADSPNAFFGSDLVNYTYYGRRFERYMEGDEWRASRSDWPLDVTGGNNQMLWQWTFANKNVTTVTSLGDHLYVERQVPIGLSVTALHDFQTSFGHVAKGSSFEYQIYDFNLESSAKFDLYSDGGDFDVYNCYSANWRDHLKFKLDVSSWPEIVNTALLTSSRFNEYWQVLLAKTGTVSTLRITRVKTIVEESNEVWIEFVLLYRHPEIGELDSELYSHLTPVLQLTPSLQRLSTTERSRSVVKSPVVDAKASFPNVSSTSLLQEFSLEAVRGSLALVVDADCTTTTAQPPTTHHTGPTKSTPSTTTTTTTTTTTTTTTTTTTKKPGTGTASNGQTEPSVTGSATTPYVPPGDNVIYTSGDLAGVGVGLLVVGLAFGAGGTFLVVVKRLHVTLMNCCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5L3</accession>
    <name>A0A423T5L3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kelch-like protein diablo</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_009870</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May have a role in synapse differentiation and growth.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002246">
        <property type="protein sequence ID" value="ROT71799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5L3"/>
    <dbReference type="STRING" id="6689.A0A423T5L3"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18445">
        <property type="entry name" value="BACK_KLHL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18235">
        <property type="entry name" value="BTB_POZ_KLHL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.420:FF:000001">
        <property type="entry name" value="Kelch-like family member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000002">
        <property type="entry name" value="Kelch-like family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000001">
        <property type="entry name" value="Kelch-like family member 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017096">
        <property type="entry name" value="BTB-kelch_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412">
        <property type="entry name" value="KELCH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412:SF466">
        <property type="entry name" value="RING CANAL KELCH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037037">
        <property type="entry name" value="Kelch-like_protein_gigaxonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="BTB" evidence="13">
        <location>
            <begin position="68"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT71799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="605" mass="67106" checksum="AAAB9649D6C1B90C" modified="2019-05-08" version="1">MDSDTENLEKQFSSRLLLRHASQNSLDESSQKHIPRSETKHKLPYRNPQHFPRAFDNLNLMRRQSQLCDVVLVADSVEVPAHKMVLASCSPYFHAMFTSFEESRQDRIVLQDIDGSALQLLIDYVYTAEVLVTEENVQVLLPAANLLQLTDVRDACCDFLQSQLHPTNCLGIRAFADLHGCLELLSIAESYVEQHFCEVVECEEFLSLTSQQVIKLISSDRLTTPSEEKVFECVMSWVGGDLPNREQYLAELMEYVRLPLLSQDYLIQRVEEEPLLKQDTQCKDYLIEAMKYHLLKGEQKALFKSPRTKPRQPVGLPKVLLVVGGQAPKAIRSVECYDFKDERWFPVAEMPTRRCRCGIAVINGKVYAVGGFNGALRVRTVDVYDPTRDSWSSCASMEARRSTLGVATLNGCIYAVGGFDGSTGLNSAEMYDSKTYEWRMIAPMSTRRSSVGVGVVSGFLYAVGGYDGASRQCLASVECYCPESDVWTSVAEMSARRSGAGVGVLDGLLYAVGGHDGPLVRKSVEVYNPDTNCWSPVADMNLCRRNAGVIALNGLLYVVGGDDGTSNLASVEVYNPKTDAWTLLPAHMGIGRSYAGVAIIDKPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T752</accession>
    <name>A0A423T752_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002184">
        <property type="protein sequence ID" value="ROT72276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T752"/>
    <dbReference type="OrthoDB" id="5959275at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023340">
        <property type="entry name" value="UMA"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51497">
        <property type="entry name" value="UMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UMA" evidence="2">
        <location>
            <begin position="102"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="165" mass="18056" checksum="41C0D3D53A20716C" modified="2019-05-08" version="1">MPPISASVTTMFHRMFGRRRSPVEGEPNADSGTEATEGQADIVNSDDFVLLGDTESQQSTMYDPPPGYTVGGANAFLPYGLDPSARPEAGQRPTSAEVQTAIDGIPFKLGSNVLLQGDADSCDISSISQMIHRINSFNWDEYEYSFQLEKSVLQEFSTREQPDPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB07</accession>
    <name>A0A423TB07_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative mucolipin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002013">
        <property type="protein sequence ID" value="ROT73634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB07"/>
    <dbReference type="STRING" id="6689.A0A423TB07"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072345">
        <property type="term" value="F:NAADP-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049134">
        <property type="entry name" value="MCLN_ECD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039031">
        <property type="entry name" value="Mucolipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127">
        <property type="entry name" value="MUCOLIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12127:SF7">
        <property type="entry name" value="SD02261P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21381">
        <property type="entry name" value="MCLN_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mucolipin extracytosolic" evidence="2">
        <location>
            <begin position="223"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="729"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="863" mass="92426" checksum="8693D48818897993" modified="2019-05-08" version="1">MNPSNHGQCHRRRGSRDDREEKEKEGEGTETGSSSSRDRNVPPPALTQQNPASPTGEQGGGGGESKGASVPSPSPFLPSPSVPSPPPPPPPSTASPSTPVQQADELERMAQVYSQPPPEIKVSGAESNGGTRYGSVSSTLGSLGAGTEYNPLNDSSNSNTARGVFAHTITADRIRRRLKFFFMNPMEKWHARRSFPGSCCCKCSRLCSDSTVVPVCPSRYNHVNYLWDTKISFSHLFIKGWDTTREIQVYPPADGPLAVYKKASFFEYLDYAVTTYAHIRETAIGTYTYEHKNGTVVPPVLCVSHYKKALPLRHRLHQTMVRPRPLPSPALPLRTVSTRPWCDHDHSPRQHFPAAPSPPDHGATTTTPLATSPAAPSPPDHGATTTPLASTSPAPPDHGAPSPALPCGTVSTRPWCDHDHSPRQHFPCGTVSTRPCATTTTPLASTSPAAPSPPDHGATTTTPLASTSPAAPSPPDHGATTTTPLASTSPAHRLHQTMVRPRPLPSPALPLRHRLHQTMVRPRPLPSPALPLRHRLHQTMVRPPSPALPLRHRLHQTVRPRPLPSPALPLRHRLHQTMVRPRPLPSPALPLAPSPPDHGATRPLPSPHFPCGTVSTRPWCDHDHSLASTSPAHRLPPDHGATTTTPLASTSPAAPSPPDHVPSPAHRLWCSFASIFLTAPSPPDGGAATATPFISIFLTAPSPPDGGAATATPFASIFLTAPSPPEGDAAATAPSAKASAPPSSPRSLSPEEAIMQQEQELSALGCRPVPIKMDVRKELSPKDTLLDKPFYPRYVTVHQCDDSRSFCQEEGCRCMRAGNSTLRKEITVKYAEGGKTAFEKRELPSDSHCECDCAADLAGKAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB49</accession>
    <name>A0A423TB49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phospholipase DDHD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002000">
        <property type="protein sequence ID" value="ROT73720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB49"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="419" mass="43612" checksum="1C811648708540DD" modified="2019-05-08" version="1">MLLLGKPKQHRDCPYSPCPCSPCPCSPCPCSPCPCSPCPCSPCPSSPCPCSPFPLLSCSPVLALPVLASLSLSPCPCSPCPCSPCPLLPLSLPPCPCSPVLALLSCSPCPCSPCPCSVLALSCFLLPVLVLVLAPCPCSPVLAPLSLLSLSLLSCPCSPCLALPFLVPLSLLPVLAPPVLALPVLALPFLALPVLALPFLALPVLALPVPTPSPSLSLTSLLRPFSISLFSPVVLLQISLSLLSLSLSHASQGQSGCQASSPIASCRDRNQYQSNANQITPAGLASSSAIPAPVAKVAVTPADKILPLLQGGGSGGKTATEGEKWARQPRREKNGQGSHGGRKMGKAATEGEKWARQEGEKWARQGRKMGKAATEGRKMARQPRKGRREKKWARQPRREKNGQDSHGGRKMGKAATQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEJ8</accession>
    <name>A0A423TEJ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase family domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006576</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001835">
        <property type="protein sequence ID" value="ROT74900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEJ8"/>
    <dbReference type="STRING" id="6689.A0A423TEJ8"/>
    <dbReference type="OrthoDB" id="6237065at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.280">
        <property type="entry name" value="AF1531-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051675">
        <property type="entry name" value="Endo/Exo/Phosphatase_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21180">
        <property type="entry name" value="ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21180:SF32">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12836">
        <property type="entry name" value="HHH_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="3">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="3">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="3">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="636" mass="70831" checksum="7A21CFD3DBBDAD17" modified="2019-05-08" version="1">MGQCTSGELPPANQDGVDGEIVTERRLSLAENISEKTSNRKFLRRRSSTTSWVSSKFGRGRKARDLSAAFNLLDYDAKINLVNINTAPEEELMTLPGVSRSVAKNIVDYRNTIGGFRRVEDLALVSGIGANKLQNFKNEITVKKKSSSRSSSRTQSVDSLSCESIRSQRSQSQSQGGRSIRGSPVRVINVNAASIFELMNVHGMNQEMAANIVEHRERKGPFKSIDDLVKVRGINSRVLSILKVYLTLNDLTPSSPPLSDVTSVASYSKVYQRNLDGKLSGHRRTHSAPLDSEDTTGRISSSLQSGDPRMSVDFYTEIFELLSVKSERPIVRDVFQGQHNGRPAIRIATWNLQELTKEKMSNPGVLEVICRTVLENGFSILAIQEVGSKDVLEKICSELNQSSLRRVREWGGPKGEWRWQVSEEPAGKIKPYLGYFKANNLDFVVVGLHIKPVSLNGKKNELNDTLVEVEDNDNSNGKDKGENQVLRESTDRKISQLGPLVTALKEKLINEREIILLGDFGMHPDNKAFDVLRETSYTNIVPADTFTNISAKNNQGTNCYDNIWLNPHTRSVYTGNWGVVREGMSHLAIPRGWLWGGMVSNHCPVYCDLYSNVSPNSSQQGSLQLSRNMGEVLRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG03</accession>
    <name>A0A423TG03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001780">
        <property type="protein sequence ID" value="ROT75371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG03"/>
    <dbReference type="STRING" id="6689.A0A423TG03"/>
    <dbReference type="OrthoDB" id="6382906at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="762"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="888" mass="95451" checksum="F037575015298371" modified="2019-05-08" version="1">MMIIPRPSYSVTTVTQAGIFPVSAHLFLVFLKGTGFALLVLLVSKLKNLLNEFDECQKRAHNEELRRQRLAYVSVSMSNVLPEEKKKKKKRAEDGEDDDDDDESGSESDSDESDSESDDDSSSSSESSSGSSAPLYTLRARSARTLREQVEDFDEMINEAIRDEMEAAAGAGNAGREHDGSGNDEDYHESDEQNEEDSDSDDMKNIRKRGRKMSNLVVKKKRRLTDLDAVDEDDAMESSSSLATEVESDDSDVVGSKRRRSSRWENLPLRRSARNRRGGDDYDSEMDERVSKKQKNKKKKRRKQSSSEEDEDELSSDSDRSYRRRKKVRKRPQPKVKGRRGSNKARGGKKNAKSKQKQKAKNPAGDDKEKKPKIKYSKPPKPKDEDQEEETLAQRRVTRGRQVNYYDALLMSDETEEEEPQKKWRGKVMKGERVPTESSEYEASDDERMKRRGVSGGLGRGKVMKGEEEDEENKSNKGKKKRGRPKKDELIGKPSPTRPSTIQPTPITTIASATLVPTAAAVPSTPAVPAVPAVPAVPSVPSIPSVPAAPAAASPVHHTPEPVASGTPPPTNPATLQTNTALPTTIAVSANIVAAANMGSNAAPINLGNNSPGHQQPLGKWSPHLSGVSGAPGTPPRSGMGPSPGAGTPPTLPGLSGAPVTASPPPPYRSSPLPLTPSGPGVPPGSTAPSNMPPVGPPTSTVVHSPGYPPYRPSEHFPAHPAFSGYPPPGRHSPNPHGVPSRHPAHLPPGHSLPRMSASAYAPPPHPSGPGPYPPRGVPPHPGVLRGPPHDLYRPPPTGHPGHGSPSHPGHPHLVMKSSYPGLEPLPYAGSPGPSPGPIGLHQGAQGSPARQSPSDDSKDESLSSKGPGEFSSGLMSYFSSQRDDDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGF9</accession>
    <name>A0A423TGF9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001758">
        <property type="protein sequence ID" value="ROT75559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGF9"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="193"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="322" mass="35456" checksum="FAF6E31DCB240975" modified="2019-05-08" version="1">MDLLLHISTSLHDLLLTRRGFTGQTGIFPEQLSQISLMQQKESDVTPPDLEKLGKDDPMSASTTPRDELAFSKLCRGHRFLTPLEESRLKCRTDTRGTYPPPCPRRGAQPRPAHPRLQGCPLATPDRGGQGLGATHGEAPLEQAATAIGLNSGTISVRSSHTAWLRDDTHATVRSVSAKVAALTGLDVEDDAGGEALQVNLYGAAGHYIPHHDFVGAHYKAWEMQPPDGRTLALHPLGDRIATFMFYMNDVEEGGRTVFPRARVGVEPRKGSAVFWWNLLPTGMSDFRTLHGACPVIRGTKWVSNKWIKHHPQLHRRPCPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THF0</accession>
    <name>A0A423THF0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Haloalkane dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005664</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THF0"/>
    <dbReference type="STRING" id="6689.A0A423THF0"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051340">
        <property type="entry name" value="Haloalkane_dehalogenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42977:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42977">
        <property type="entry name" value="HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="100"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="357" mass="39639" checksum="CDAC11A1436531C4" modified="2019-05-08" version="1">MQEVRLSDSQPHFACVRWFPWPSSPRCWLLWGPPWGPPTSTSTLVMIGDPPVVRTPDERFATLPQLGYPWTPRYLQMKHQGNQFLRVHYIDEGPRDASETLLLLHGTPAWSYLYRKTIPTLLAAGYRVVAIDHIGFGRSDKLTDPAAYTHELHVATVVNTVRDLDLKGVTLVGHDLGGPTGLSALSRDSGRYRRVVLLNTWLPQGDMFSSLSSIKEHLPYLSFRGLTQVLGRNVPIETVFSVATQSSAAELQGYVAPYPSSLYKAGPSRWPLLIPTSSSDPMGVENRRVAAFLEGWGGPALVAYSDREVFTLPGRDLFRRLLPRACTATVNDAGHFLQEDQGPAVAKLIVQFIHGQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THN0</accession>
    <name>A0A423THN0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative transcription initiation factor TFIID subunit 4-like isoform 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005534</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001715">
        <property type="protein sequence ID" value="ROT75905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THN0"/>
    <dbReference type="STRING" id="6689.A0A423THN0"/>
    <dbReference type="OrthoDB" id="21060at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08045">
        <property type="entry name" value="HFD_TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000015">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1110">
        <property type="entry name" value="TAFH/NHR1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045144">
        <property type="entry name" value="TAF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037249">
        <property type="entry name" value="TAFH/NHR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003894">
        <property type="entry name" value="TAFH_NHR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138:SF14">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07531">
        <property type="entry name" value="TAFH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00549">
        <property type="entry name" value="TAFH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158553">
        <property type="entry name" value="TAFH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51119">
        <property type="entry name" value="TAFH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFH" evidence="8">
        <location>
            <begin position="56"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="389"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="54877" checksum="D24B6E795CCE52E9" modified="2019-05-08" version="1">MATQAGTAVNPTTVPVTPGTTVAGTVVPSTPTTAAAPVTQTTQPAAATGGSQTISAESAKTKCKNFLATLLKLANEQRATVARNVRNLIQGLIEGRVEPEVFTEELQKDLNSSPQPCLVPFLKKTLPYLRVSLARGELTIDGVRPPPLSAVTPVTGVTTVIPAMSVARPGAPTTSGTVRTIAPAAATATTVVHRPVNATSTPARVVGQQQVQQVRVQGGKTVVTTVRQNTTAASSPASTTTNTVPTATKTITVNKTIPTKDKEKSNKNQLFTYSGVADDDINDVAAMGGVNLGEESQRILESTGFVGTQIRSCKDENFLLNTPLTQRIKQICSKYGLEEAPKDVVALVSHATQERLKTIVEKLAVISEHRLDIIKSDSRYEVVQDVKGQLRFLEELDKLEKKRKEEQEREMLMRAAKSRSKSEDPETAKLKAKAKEMQRVEMEEMRQRDANRTALNALQGPKKKPKLDLSAMDDRLWLPLSSSVGQVGDGSQVQGRTIAETVRQAQQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIM6</accession>
    <name>A0A423TIM6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Insulin-like binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_005124</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001675">
        <property type="protein sequence ID" value="ROT76300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIM6"/>
    <dbReference type="SMR" id="A0A423TIM6"/>
    <dbReference type="STRING" id="6689.A0A423TIM6"/>
    <dbReference type="OrthoDB" id="5985519at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005520">
        <property type="term" value="F:insulin-like growth factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001558">
        <property type="term" value="P:regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011390">
        <property type="entry name" value="IGFBP_rP_mac25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14186">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14186:SF19">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="39"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="16663" checksum="4F2DC3C0E71CFE48" modified="2019-05-08" version="1">MATPGQCLLSAHQQKKFNSRPHTPTRLTPPTLSTPPTAPVIVSAPEDAERPEGSILVLDCEVKGYPVPDVTWELNLEDGSSFKLPGDMSSLAVQVRGGPEKFMATGWVQIMRIKKDTVGTYSCVATNSEGEARAAAKVQIRRAANEKEESLNMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TL93</accession>
    <name>A0A423TL93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trypsin-like serine proteinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_004177</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001561">
        <property type="protein sequence ID" value="ROT77187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TL93"/>
    <dbReference type="OrthoDB" id="8440449at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="36"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="127" mass="13620" checksum="5EEE583F9194C6D6" modified="2019-05-08" version="1">MDSYTYTQNYTGPTASSLSLGVSGQLHVHTNYTGRIVGGVEARPGEFPFQVFLSVTKFGTQFLCGGALLDESRVLTAAHCLEGVAAPEDIRHGARGGDHASSVGKPHPEGDNRSEVPFRCVIFLLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMA0</accession>
    <name>A0A423TMA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001509">
        <property type="protein sequence ID" value="ROT77586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMA0"/>
    <dbReference type="STRING" id="6689.A0A423TMA0"/>
    <dbReference type="OrthoDB" id="2448405at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052126">
        <property type="entry name" value="Spindle_Org/Thrombomodulin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24036">
        <property type="entry name" value="SKELETOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24036:SF5">
        <property type="entry name" value="THROMBOMODULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="282" mass="31838" checksum="EE3D1124331F9B1D" modified="2019-05-08" version="1">MLPTKARGCRGGCSGYAMAAAPLSHSWICGARCWRYCLLFFFRSRENGNAIGEVAKCKYSHSKKSAARRARRERKSARSFVPRSGLRGCLLRPASPCNRHFKHGRPARWHVPMPTAAPRCLTRPHGARSLPRLPSWGIAWWINDLLIPEIYVERGQTYYFTVYGGNDKLNSPTYHPLYITNSPEGAGGLCEWRHEGLDAWEDSITFEEYKETLYKDCDAEPPGSLIWTCYTHRNLGWKIHVVDSGYNLRQEGISSGPTLTPLHTHLATLAALLLPALMLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TP88</accession>
    <name>A0A423TP88_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable RNA polymerase II nuclear localization protein SLC7A6OS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_003016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Directs RNA polymerase II nuclear import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IWR1/SLC7A6OS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001403">
        <property type="protein sequence ID" value="ROT78286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TP88"/>
    <dbReference type="STRING" id="6689.A0A423TP88"/>
    <dbReference type="OrthoDB" id="6255506at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040218">
        <property type="entry name" value="SLC7A6OS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013883">
        <property type="entry name" value="TF_Iwr1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31196">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31196:SF2">
        <property type="entry name" value="RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08574">
        <property type="entry name" value="Iwr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Transcription factor Iwr1" evidence="11">
        <location>
            <begin position="179"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT78286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="314" mass="36215" checksum="BE536EBE6F845F43" modified="2019-05-08" version="1">MMATIIRIKRRHDEEPTENIIVKAKRSRVEEEDGAAALCESSPESSHTIMTRVGTVNSKEDDVQQHVLKVMKEHKTGWQLREQYKKLGNAHSIKASVKEAVKNRVNSKRYKIVAACRGIEDKTDQKGNCQIGEKKDVDESETAVAITTEEYKLYDAMLPEIDTKEDVITCNGIPMETEKYVYDIYYTPQSVDWIENICEIEKHHLQLYNGSDSEDEDALQDDDDENDENNWRNDYPDESDDSHYSDEIDYLNAQIRKVTGKSYDTDESYDVDEYEEDFDEDGNLIECGYPDSGMKLRRGIREMLSNDENDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTE7</accession>
    <name>A0A423TTE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001196">
        <property type="protein sequence ID" value="ROT79744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="487" mass="53562" checksum="0ED2817D66273A81" modified="2019-05-08" version="1">MSALLFPGRRRVARPCFSSWGIEGFSSFLSFPYFSLFFPSLHFCYLFPTFTSCVQPSISFLFLSHVLFLCLCFSILFSFSITSSSFPFSLSILLLLPPPLPVFRFTPLLFPLSLSPVFRFIPSTSPCSSLRFSTFYYVPTTILPFPLSHLSPSYSLLPRLLISSPTFSLPPPSNPFPFPRSVLPPFFPLFCGPLRSFPFSSLSLSTFSLPLLPSFPLPPIALTLPFSPLPLPLTPCIRSPSFPFSSLSALPTLSNLPPPSIFPPLPSLSSLPRLPPPFLCPYSPVCPFSSLPLLLPHPSHQAFSLSPSSPFLPPAYPLFLSPSFSYPLPFPLTPLSPLPPSPFSLSLPSQPFYLSPPPSYPSAPYPLFHLNRLFGGASPSSFSPLSSGYPSPLLPLILSLPSSHLLCFPSSRQAPFPLTSSFSHPPFSPPPSFPFTPSLCAPADCQEPDDGPPPSRRRPGRRQEEKERRQDQSPFKEVRSCAARKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVT5</accession>
    <name>A0A423TVT5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc/cadmium resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_000679</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001105">
        <property type="protein sequence ID" value="ROT80583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVT5"/>
    <dbReference type="STRING" id="6689.A0A423TVT5"/>
    <dbReference type="OrthoDB" id="29444at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010312">
        <property type="term" value="P:detoxification of zinc ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000010">
        <property type="entry name" value="Putative zinc transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="72"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="299"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT80583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="412" mass="45479" checksum="8C5B43D8FAACB866" modified="2019-05-08" version="1">MSVWWEFGPSALELHPRLLLCVSPPPSLSLLHPPPPCFLDCHVADSIVPIGKQAWRGRGSMGRYTGKKCRLLTMFTMTASFFLVELIVGYITNSMALVADSFHMLSDVLALVIAFLGVKMSPKKWSKNTFGWARAEVLGALVNSVFLLALCFSIFVESLKRLYETEELHNPQLILVVGVIGLVVNLIGLGLFHDDNENDERFTPPPPNSVGANDKHGNGTPRREASAQMNMRGVFLHVLSDALGSVIVIISALVVWLTEWEYSKYIDPALSLGLVTLITCSTWPLLKDSALILLQTVPTHIQVDGIQKQLLNVDGVLAVHEFHVWQLAGERIIASAHIRCRNLKDYMVLAEKIKKMFHEEGIHSTTIQPEFVEYEDDGASASIDSAEDCILDCPSKDKDGCVANTCCGLSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWI8</accession>
    <name>A0A423TWI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001064">
        <property type="protein sequence ID" value="ROT80823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWI8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="47311" checksum="7C8D44B687644114" modified="2019-05-08" version="1">MSMHSFDHPSPSLSLLIFHLLTLPVLLPPLLSSLIPSSLLLPIPFLTLSLPPYRPRLSPLNPLSCLSSLTLPPSHPPLFLNTLLLLRITPPFSQPLLLSTPTSPPPPAPPLRQHRSPSPPLTPRMRAEKCSSPSRFLSSLFNPLISSSLISLLLSGRLPHLSSSLSLSLLSYPLLSHPPPSSSPSPLIIISLSSLARSYCAFACSLSLPSSSLVFLLSLLGLSLSLFSPIPLRLTLSPFSSPPPSLFSLSVLFLFFSFISLSLSFLFSLCNFSFPFPFFLLTSSLSSPCLFLLCPFPLLSLPLIPIFLYHFLPPFHPLSSSPLTSSPSLFSPFPRPIFPLPDSPLSPGPLPPHPPPFPFPSFSSLSLMPEHPSTLPSPPHLPSTPPPHPPTPLPSFNPLLPPPHRFHLESQEGKFSKPGKKENFERGNFPNRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXE8</accession>
    <name>A0A423TXE8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001016">
        <property type="protein sequence ID" value="ROT81115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXE8"/>
    <dbReference type="STRING" id="6689.A0A423TXE8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="61311" checksum="BD07B3A6985BBF4A" modified="2019-05-08" version="1">MAFRSTFVERIFNERQPLKSQGYITFHFPSLAPTFSHSPPPSLPLSPSNSNPPPPFNFLTSTYTFPPSLSSPPSLLHFYFPSLISTFPPSPQTQPSFPHFQLPYLHLHLLSSLPPLPLPQLQFSPSLTSPSTLPQQHLHFPSLISNFPPFTSTFPSLISNFPPSPPLSLPSPTPPPPLPHLTATSLSSSFCQKLNQSRSISNQHNRLRFELSRSAHSNEAQESNTESDKNDSDEYVYRNIGLVRLVRDILHSIFPPSPPPSLTHLHLHFPFLTSNSNPPPLQLLLPPPILSLPHFRLLLPSFTSTFPPSSPLFLPHLKLSLPSLTSNFLTYTSTFSPSLPPLPLPPTPVFPPPSPPLHPPSATPPLPFPYLQLPSLTSTFLPLSPTSLPHLHFPSLHLHLHLPSLTLQQPLSPHFVQSLTNRDLFRTSITDSDSSCLEALIRTKHKSQTQNRTKMIQTNTCIEISAFPFTHKTLPPPPLLSHSFTLPPLSLSPSHSPPLPTLTPLSLLPLTTPHHPLSPSSFLPSFTLFLTLSHIHFLSPLSLWLRSDTRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYE2</accession>
    <name>A0A423TYE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_025436</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000977">
        <property type="protein sequence ID" value="ROT81412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="503" mass="53411" checksum="E582321C5FA59861" modified="2019-05-08" version="1">MQSERPLSPASALPLSLTSSLSSSLDRLPPLLASCPSPLLTPCSLPSPCSSSSSPIIFLASPHSLAPLPLPSLPSCPPSLLPLASCLLPPLSPSPLLALLPSRPCPLLRSLTSPFPSLPCPHSLAPPPGTSHSLWFSSHSSLCPLPQLSPSLPCLLPLAHLLALHTLFGSLSIPLPRTPSPWSSDLLSPYFLFLDPLLSSFQCPLALSLFLASLPLPPPLFFFFLSSLVLSSPSPFAHLPSFLLPPFPCPRPSLPAALPSPCLFPSPVFPFPFTLSLSFPPLLSLSLVTPCLPPPLISFLSPCFTLPFSFLVSLWLFPHSLALSLPRAPCPLSFQVPLCLALLLPVPSPSLLSPCPSAFPPPSLPXPFALFPFSSPSNFLALLHLPRLLLPSPSPLAPFPPPLPSPLPLPLPLFPLPPLLPSRPPSSFSLPSPFPRSLALTLCPPPPRHFTLFMVLFPFFALPLAPALSPLSLAFSLWLTSSPFTLSLAPYPFPCPVPSPLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1R0</accession>
    <name>A0A423U1R0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_024180</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000791">
        <property type="protein sequence ID" value="ROT82648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1R0"/>
    <dbReference type="OrthoDB" id="6506757at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="10">
        <location>
            <begin position="106"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT82648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="438" mass="48458" checksum="183ECFD3FBCA4208" modified="2019-05-08" version="1">MYVEGPDDDPIVSGSLPAVLDIIFNHLGYCYEYVVVPSRSGGIRLPNGSWTGFEVDMSGVPMALTHDRFQDVEATEFLYIDGWSAGFRRPVLQSDVSGFVKPFSAYVWLFIAAAILGVLATIWFVYTSHETIAKSRDTRGGYPGLGAFRTAGNRLEGTPNIAKESVLWTVALFLSQSVTKTPRGNSVRVITGVWLLVSLILTTVYRSNLKAMLILPKVVLPFDSPEELAETRIPTWIPMGSAMHTAALKSPPGSAMARVLQHSISLDSATDVPWGVRDMVAGKHAMISPRGALIAIMHDTFSKTGQCPYYVMSEDLIGMVQLPILLRKDSPLKKELDPIIRRLREFGILDHEYRKQVANATECLKPIGSQGARQLRPLDLGDFYGVFMLYAGEPSKKWHKIMAVKATLPNHQCHHPIHRKGIVYPVYTIETSKTTGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U210</accession>
    <name>A0A423U210_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000781">
        <property type="protein sequence ID" value="ROT82735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U210"/>
    <dbReference type="STRING" id="6689.A0A423U210"/>
    <dbReference type="OrthoDB" id="438268at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF29">
        <property type="entry name" value="NEOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="754"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="45"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="148"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="243"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="334"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="441"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="549"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="647"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="912"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="926"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="952"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="982"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="997"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1015" mass="112098" checksum="0220DE582D55B4AF" modified="2019-05-08" version="1">MLIERSHFYLYRCRATNSVAGKERHSNGISVTVLERGEGDNYKLPSFLSPKDPVRVVQGENAIIECLATGVPLPTISWQRKLNESAGWEDLKMGVNGVSMIGQGTLVLSNVQNTSSGRYACTAKSYNPNTKREASVSRERELDVMTPPEVIDSPKPVNTLSAKTARLNCSVTGHPTPRVIWYKNGRPVFIKGRIVQSDTNQLLFYNSITADKGMYQCLAINDAGYASSWAHVVINSSKNQPEPPQNLNYVVLSSTSVLLTWDAVHPLNGKIKAYSVHYVESESSAMERQEVSLNTSLLLEGLKPNTNYTAFVRAYSSFPSEISESLVFRTAEDVPTDVPAVQLVPLSPTTLLVKWTPLAPEQARGTIHGYKILWRKRNHHYYHVQEVLADVHEFQITDLHPGKKYEVQVLAATKAGYPTKSGWPWIQQKMGEPTQDVPFPPEVTLKVLNDTSSDSAGRLAIKVDWEVSSENKVEIEGFWLKYKRQDQTWNEPITFLPTQKSYTITGLEADWYEVQVKALSANGDGEPTVNVIHTRLPNQSTQFANTTSSIDRLEADSRSQTSVHLSWRVTEGQDGAAYYTVKYQQITHSPNPAEATFVRSDTTEIVITGLKPFSTYEFSVRAHESEKTYGPFSHPVQAMTMGNLPSAPKDFMYEPTDASTIRLKWSPPEQLTGTLKKYEILYSLDKQKPLSEWDVQEVEGDATADTVGGLVSNTEYWFRIRGCSAVGCGESTEPLSATIPAILPPDQKAPSSEFYLILCLVTAFFLLTIIGVASLYAVKVRNISSSPRVLACNGNGHINGKRNTQVVKIGQADGQADGDCQEMEVYIPMLTQIPPDFKCTPLDTKGGYPETRMNGMNNPRCNGFVVRNRDQLQAVPHAETKGLSSEESERLVIGASSSNGAMSMSVLPQVYQNHSQEQREAEQGGSEPNHSQSGTLPPSPRHEHNHSGASQTGLANLTNLTTLSTTESDVEMEPEKMMADSVGSQDASTPYQHNSHHTTSATKTSSPQPPLTTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2L6</accession>
    <name>A0A423U2L6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="10">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_023887</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01000758">
        <property type="protein sequence ID" value="ROT82939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2L6"/>
    <dbReference type="SMR" id="A0A423U2L6"/>
    <dbReference type="STRING" id="6689.A0A423U2L6"/>
    <dbReference type="OrthoDB" id="9215500at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04300">
        <property type="entry name" value="GT35_Glycogen_Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000005">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000153">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000197">
        <property type="entry name" value="Alpha-1,4 glucan phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011833">
        <property type="entry name" value="Glycg_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02093">
        <property type="entry name" value="P_ylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF13">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="833"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="836"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT82939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="852" mass="97837" checksum="3A01E093B47863A3" modified="2019-05-08" version="1">MAAPQTDLEKRKQISVRGIAQVENVGNVKKTFNRHLHYTLVKDRNVATPRDYYFALAHTIRDHLTSRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSACDEALYQLGLDIEELESLEEDAGLGNGGLGRLAACFLDSMATLGMAAYGYGIRYEYGIFAQKIRNGEQVEEPDDWLRFGNPWEKARPEYMIPVNFYGRVEDTPQGKKWVDTQIVFAMPYDNPIPGYKNNVVNTMRLWSAKSPNNFNLKFFNDGDYIQAVLDRNFAENISRVLYPNDNFFEGKELRLKQEYFMVAATLQDIIRRFKASKFGSKDQVRTDFDTFPEKVALQLNDTHPSLAIPELMRILVDIEGLSWAKAWGICVKTCAYTNHTVLPEALERWPTSMLEHILPRHLQIIYEINHFHLQEVSKRWPGDMDRVRRMSLVEECGEKRINMAHLCIVGSHAVNGVAAIHSEIIKRDIFKDFAEMNPEKFQNKTNGITPRRWLLLCNPALADVIAEKIGEEWVVHLDQLTKLKPLAKDAGFIRAVQTAKQENKMRLAKQLEQDYGVKVNPSSMFDIQVKRIHEYKRQLLNCLHIITMYNRIKANPGAPFVPRTVMIGGKAAPGYHTAKQIIRLICAVGRVVNNDPIVGDKLKVVYLENYRVTLAEQIIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTLDGANIEMMEEMGKENIFIFGMTVEEVEELKRRGYNAHDYYNRLPELRQCIDQISSGFFSPSNPDQFKDLVNILMYHDRFFLFADFESYIKCQDSVNKLYQNPNDWTSKAIMNIASSGKFSSDRTIAQYGREIWGVEPSWEKLPAPHEPRDTDITREEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3K7</accession>
    <name>A0A423U3K7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Synaptotagmin-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000705">
        <property type="protein sequence ID" value="ROT83279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3K7"/>
    <dbReference type="STRING" id="6689.A0A423U3K7"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017156">
        <property type="term" value="P:calcium-ion regulated exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000005">
        <property type="entry name" value="Synaptotagmin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001565">
        <property type="entry name" value="Synaptotagmin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024:SF374">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10024">
        <property type="entry name" value="SYNAPTOTAGMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00399">
        <property type="entry name" value="SYNAPTOTAGMN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="17574" checksum="DFB82A0DB8EA565A" modified="2019-05-08" version="1">MLSLCYLPTAGRLTVTVIKMRNLRAMDITGSSDPYVKVCLLCQGRRIKKKKTTVKKSTLNPVYNEALVFDIPNDNIEDVTLLVKVVDYDRIGANELLGVTVIGSQVIGPGRDHWLEMLECPRRPVTQWYPLMESVPLNLVTSPTRSLPPPLTCFNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3N6</accession>
    <name>A0A423U3N6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cubilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000703">
        <property type="protein sequence ID" value="ROT83313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3N6"/>
    <dbReference type="OrthoDB" id="6369184at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24255">
        <property type="entry name" value="COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24255:SF31">
        <property type="entry name" value="CUBILIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019211047" evidence="4">
        <location>
            <begin position="24"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="130"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="281"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="417"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="619" mass="67886" checksum="286AD34A4C966683" modified="2019-05-08" version="1">MVGARWLSVAVVGLSVIVPPALPCPISASSDPDAASDDCWTRDSGWPLRLSGRNDDIDAVGGGEAVALAGNSDFRFFEIDEDDSEYVPRRSVDYEDKIDQEALTLKEMAFEQALIMQGRSSGDRGSASFCDQFIPREEFYIHSPAYPNNYPANLTCRYQIYRRHPDYCGVAFTVLRLDLAQPHPAVLAADDSSRNNMVEGRGQQNRTCGGGDVLLIEDVVHCGRYQRGKTATFSFPGTLLTVEFRSGANHGASGFLLLGRQVKTCRTPRTLGSPLTSSVQCDRMIDSSMFLLTSPEYPAPYRHNAECHFAVRRLEPDACGVQLTVKDFDLEESGCMFDYVEVQGQRLCGSLEQGFSRYFRFEGNELDIRFRTDESTRRKGFSIAGQQVLCRQARPIQAPLSQARPSKADDAQLGVEARAPDPPETTLAPLGPFPLPPSRSTQRRHPISTRPPLGRDSTEGFLEDAKEEENFTELEPGLISTTTVEAETTNSEQNVPGDPDFNPFTTNGLPPTIPTTIPGLTPTNPTTIDYPTTFTNIFPTTFTNTFPTTEIEFPTTSLAGTECDQFFVDVSFSISSPGYPGPYPNSVDCAYVVGRASLDVCAVSGFDIRNGSSQRGIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6R0</accession>
    <name>A0A423U6R0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">G-protein coupled receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_022449</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000555">
        <property type="protein sequence ID" value="ROT84377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6R0"/>
    <dbReference type="STRING" id="6689.A0A423U6R0"/>
    <dbReference type="OrthoDB" id="6022531at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016500">
        <property type="term" value="F:protein-hormone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009755">
        <property type="term" value="P:hormone-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15137">
        <property type="entry name" value="7tmA_Relaxin_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002131">
        <property type="entry name" value="Gphrmn_rcpt_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24372:SF77">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24372">
        <property type="entry name" value="GLYCOPROTEIN HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00373">
        <property type="entry name" value="GLYCHORMONER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="154"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="31"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT84377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="679" mass="77003" checksum="323EFC68BAEFE55D" modified="2019-05-08" version="1">MLYNILYIYIYILYIYIYIYHSTPHPTPPLTTSHYHPLPPPPPPTTHTSPHPTLPHLTPSPPSPHQPHSLHPLPPPSPLPQPFTPPSHHPQPPHPPTTLPPPTAGQTNFRFCCLAREVRFCHPPPDEFSSCEDLMTNIMLRVCVWVLGTVAFTGNLLVIVWRFIYHHDNKVHSFLITNLALGDLCMGIYLLIIAAVDVNYRGVYFIYDALWRTSSLCQLAGFLSTFSSELSVFTLTVITLERFVVIIFPFRVSRLNMNWTRIIMGVVWASVGVLAALPLSNIHYFRLEKSLLFASVFYRCFVELLREVGCLPRPSHHTREAEWWQYSVFVFLALNLISFSVIAASYWGMYRAARTTSAAVIRSDQQRRDSNMAKKMTLIVVTDAACWLPIILLGFVSLAGGRIPPQVFAWVAVFVLPLNAAVNPLLYTLSTAPFLGKARERGVGRATLLQEVDHSAYPVTTTGYNNIHRQHSAMSTTNNQPTISTKQQQCLPPTLSTNNNFHNNSNVYHQHFSTNNNFHQQQQCLLLTTISILPPNTFTNNNSTNNSNSTNQHFLLTTISTQQRNVYHQHFLLTTISTNNSNVYHQHFLLTTISTNNSNVYHQHFLLTTISTNNSNATTNTFYYNFHQQHNNFSTNNSNGLPPTTTTNFTNNSNVYHQHLSTKQQFPPTTAMSTTNTFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7N7</accession>
    <name>A0A423U7N7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">nitric-oxide synthase (NADPH)</fullName>
            <ecNumber evidence="4">1.14.13.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_022060</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NOS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.39" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000505">
        <property type="protein sequence ID" value="ROT84715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7N7"/>
    <dbReference type="STRING" id="6689.A0A423U7N7"/>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004517">
        <property type="term" value="F:nitric-oxide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006809">
        <property type="term" value="P:nitric oxide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.340.10">
        <property type="entry name" value="Nitric Oxide Synthase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050607">
        <property type="entry name" value="NOS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044943">
        <property type="entry name" value="NOS_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004030">
        <property type="entry name" value="NOS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036119">
        <property type="entry name" value="NOS_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43410:SF1">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43410">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02898">
        <property type="entry name" value="NO_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56512">
        <property type="entry name" value="Nitric oxide (NO) synthase oxygenase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitric oxide synthase (NOS)" evidence="13">
        <location>
            <begin position="93"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT84715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="18291" checksum="6CAB79BFB2419CB9" modified="2019-05-08" version="1">MVKKACPAHPQRLANFSLKKEVVDTLQSQTNEEGVCSGRVCGGSLMNIRRMSLAPRPPALVRPRQDLPRPVLQGHPRCKPDSREQRHNVAARHFPSFRYDSAEHKGRWQEVSRSVAKRGTYDLTFDELVFGAKLAWRNAPRCVGRMQWKRLQVRPRLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8L6</accession>
    <name>A0A423U8L6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4745 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000455">
        <property type="protein sequence ID" value="ROT85001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8L6"/>
    <dbReference type="STRING" id="6689.A0A423U8L6"/>
    <dbReference type="OrthoDB" id="6367651at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031813">
        <property type="entry name" value="DUF4745"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15923">
        <property type="entry name" value="DUF4745"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4745" evidence="2">
        <location>
            <begin position="72"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="39959" checksum="BC0ACD4DD273D5FB" modified="2019-05-08" version="1">MRRSGPGGGGGGGGFSKPPPAPLTHGGSGRVRLHTPEVNGTHVKDRFGSPRERSPSLVSSLPLSPSHPSSREKSPNPASQDLHDCSMCLSAYIQSLNTVCGTACRLSQCLAQVCTEAGFVDPYSVPGMTTQPVREAADAWEGVARAVGVASAAVKTQMLVLLQEVQSRQDMSDTIRRQEISRVAQAMLSAFLGLQYQFSAVVIERFTAILQALRDDSQSYGCQSMTSQGLPSQGVPSQGISSQAPMGLPMGGKTCQGPLPGQVGEPQQLPVSSQYVPQVAGQPSWPPSGSQPPPPPSLPPGLKGVQPVPLLESPGKEDKPRSRHPSGGHSRHSPAAPGWSNPGSAVGVPNNTSYNSNSNYASLVKHVVTHCHPAHAMGSFHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9Q0</accession>
    <name>A0A423U9Q0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WD repeat-containing protein 79</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCAB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000283">
        <property type="protein sequence ID" value="ROT85420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9Q0"/>
    <dbReference type="STRING" id="6689.A0A423U9Q0"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030576">
        <property type="term" value="P:Cajal body organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00041558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="345" mass="38776" checksum="8E296BBC9F932FDF" modified="2019-05-08" version="1">MEDNYTKGCKWSPDGSCLLVGSVDKKLRLFNLPNPVAMGQCLDESWQAESERYNLPAVTVRERELIYDYAWYPHMRSDNPQSCCYQSYDHLDQLVAAKSVGFSLDGSMLLCGFKKTIRIFHTSRPGRTFETIDAKGQPGIISCMAFNPRLPNIFVAGSYLGNLGFYNTRRNNLFCRLDGCTGGVTQVAFSSCGIKLFTGTRKDDEILCWDIRKLGTILYSLKREISTNQRIYFDLEPELCRYLVSGDTRGKVLKWDLDQQGVTECGDSVPVLQPSASFPAHKDCCNGISLHPYNAILATSSGQRHFPEPVESDSSSDESVSKPMFSKKKITQENTVKLWWLGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA96</accession>
    <name>A0A423UA96_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative baculoviral IAP repeat-containing protein 7 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000226">
        <property type="protein sequence ID" value="ROT85626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA96"/>
    <dbReference type="STRING" id="6689.A0A423UA96"/>
    <dbReference type="OrthoDB" id="6337722at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050784">
        <property type="entry name" value="IAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10044:SF139">
        <property type="entry name" value="DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10044">
        <property type="entry name" value="INHIBITOR OF APOPTOSIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01282">
        <property type="entry name" value="BIR_REPEAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="367"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="337"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="46307" checksum="C91D3C3A635A9A7A" modified="2019-05-08" version="1">MAGDEEQCSRDKVMESPPRQERCFLTPLDLLFESARRLTFARWDESQLPSTQLARSGFFFTGVKDHVQCIFCLGILGCWSPGEEPDEEHRRQFPECPLVTGAPTGNIPVDAPSREGAEGRLYRMLREYYLFRLNNMRFSGDFPEGGTQTPADAYPQFRTPASRLASYVGWPAEVGLCPQVLAAAGFFHSGRADWVQCFSCGGGVFGWQKGEQPLEVHLRYYPLCPFARAAAAPALPSGVAGGTKRALAIPTEDAELLLQHPLAKRLVEMGLPQSVVKGAFKQRLETYGAICRTLLEAVELTVEYKKPGKHNPQLGTSCTSRFSPPIQTESPQQLSYFSTYNEKAEILRREVEDLKQQLQAQENRLLCRVCKQDRVAVVLQPCSHLHLCLSCARPRDTCPSCDHLIRGTLRPMIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAK6</accession>
    <name>A0A423UAK6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008426</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000206">
        <property type="protein sequence ID" value="ROT85715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAK6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="41791" checksum="6397C4B551728E50" modified="2019-05-08" version="1">METRSRFHFQGTRFLPCCPKVKEERNCSRLPPLHFPLKGKGRVLTPSLLLSFVFFLFHFLPNIFLHIIPFCSFSLAFLPTILPYYFPSSFPTLYLHPIPNRPPPSPFSPTHYPSHSPFPFPHTLSSLLSLPSQPTLPPFLSPTSPIPPPNPISLTPPPPSSSSQLPSPPHPVLSPSPQPSLCSSPTQPLPTPTNHSHPPSSPPPPSFPPPSFSSPLHPPPPPSSPHLPTPSPTTFPTPSFPSPTPLLPLPPSHPSLPSFPPSLAQYLSQAMREFGGGTSTCVSESPTHYSSCAISFFFSSPSVLPLFFPLSFSLSFYRRLPASPSLSSSQPTYPSISPLPLLVILSLVPHQICLLPFSSFYLLVIHCFPANIPFGRVCPLKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAQ4</accession>
    <name>A0A423UAQ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nipped-B protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007149</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCC2/Nipped-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000191">
        <property type="protein sequence ID" value="ROT85782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423UAQ4"/>
    <dbReference type="OrthoDB" id="418242at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061775">
        <property type="term" value="F:cohesin loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140588">
        <property type="term" value="P:chromatin looping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23958">
        <property type="entry name" value="SCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026003">
        <property type="entry name" value="Cohesin_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12765">
        <property type="entry name" value="Cohesin_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="8">
        <location>
            <begin position="1614"/>
            <end position="1794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="729"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="881"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="172"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="321"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="895"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="918"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="993"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1007"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1954" mass="221765" checksum="EDCB33C230EEFA38" modified="2019-05-08" version="1" fragment="single">TNSLVAEEAQRLLSCQDPALVEQLANSLALTHADHIELKEQYAGTDSSILLRNAPPLLEGILRVNPAVFTARQGGSEGGAVIKTECGKGISSVNHSSPSKHINNVSVIQCGPVLANATQVKVKTEPGGPSPPASLPLTKPDGQLEKHHGHKLANKQDPQTDESYGKRNLVPKSDRQSDKSVDKDEDKSSEKHSKRSDKTSNKGTKSESRSAHVTPEKEKASPNHTQDNKNKESNDNAIVAAKAMKEPVVVLNKLSSEELKSMGRIPKLSGVGSNKPEKTPDTPRNSSRSSRGQRDAKKYREVSSDSESSEEDKKKPNKYFKNREREREEKKKKDKADRKRNRVQSDEEDYNPDQESKRRRKGAHDSSEDEDSEYEEEGSKAPKRAAPAPLQKKPSYTNKRLERKLVPQTEKLTTEELMETGVYQRFNRAVEKIFDNTEDLDLSAEIEEDGDVPQEYLIPKYELSDLCSEAAKLKSLGAMAIVPPERLVRLLNILEKNIRDGAKVTPIVDEEDEDDDKLWMELVMERILRGMDASLTAMNILTSPNMSKRVYLEDVIERCVQFTKFQLSNTIYPSFDPVYRVDSKKDGYVGTVKRKRTQCKDVRNRSIIGLYNKLHEVVGLLADLLSIQTLTDTTVLQLSTLGVAPFFVENVSELQLSALRLVTKVFSKYNKHRRLLLDDILASIARLPNSKRSLRTYRLNSDENIQMLTALVLQLIQCVVELPEELAQDNKNKSASDGDTQNSKDSKDSKVEEKKPELNMDRDVLVCNRYETAMTTAYSFLSVFLQKTGSKNEEIDYRPLFENFVQDLLATVNKPEWPAAELLLSLLGKLLVQKFSNKNTDMALRVSSLDCLGVVAAKLRRDAVSSQLELENIKSIIQEVREEENRDAPMLEDGSPPTENGTTGPSTPSSKKSKKKKSSSEKAKEAEVQSDEEEERTMFLQRVLLDWLAVNSGSETALLHARHFFIGQWYREAYTEIMRQKQGPLPQSNTRKGASHNKKKRKRKGDESEEESTGESDDDDDDDDVKKGQVDEALVAEVTQLAERRKLFLLTKVPAFPPASPGAKTQTLQTHIGYENAELITRYLASKRPFSQSFDMYLKQILRVLTESAIAVRTKAMKCLTMVVEADPGVLSRNDMQMGVHHSFLDHSTSVREAAVDLVGKFVLSRPEVLNTYYNMIAARILDTGVSVRKRVIKILKDICLECPDFNKIPEICVKMIRRVNDEEGIKKLVQEVFQNMWFTPVRERPQLDEESLLRKVNNITEVVIACKDTGLDWFEQLLHSMFRPKEDKDDVTKVNTEPPKSLVTACKQIVDCLVRHILVLEEGDLENQPADQPRTTSQRLLACHQTLYLFAKIRPQLLVDHAITLQPYLAWRCRTQVDYTMIGVVARTLELVVPLMEHPSETFLSQLEEDAVKLILQHDRTVITSCLALLGSIVNTVTKNYRLIKDCFNRYHSFISDYKRLNEENPDNPRLENYKPFFRRALYTIGLLLKHFDLKNQVVRCGLPDNITEQVFETLMYFMGLPDINLQYCTLQAVGFVCIRHYELMMGSRLKQLYHMMLLDPSVNTKLRIQTLQNVETYLQEEEIRMIKQDQEWAKQKTRENLKEMCDVQSGMASAIIQMYLKEVLECVVAGSVVVRHSALRVIQLVLAQGLVHPVQIVPYLVCMSTDTEEIIAHSADKQLQDIEKKYPGFIGMKAMQGFRLSYRLQSLIQPAMPTRGFRTKEGEIPGALNGFLYSIMRTTKQHRRAVAFSLLKQFEEQARTSLTELLFIADNLAYFPYQVLDEPLFIIHHIDIMISVTGSNLLQNFREALLPPPNAEMKINPETRQPEYVDDLDDEEDVEVYLSRLPPCLTPLVECINASQGCLLLLMLKEHLKEIYGITDGKISQYSPSDTSKQYEKGASRKSASKFNPKAILKRLKEEPVSDVDMVDDTRQKVDLITQYLDVSAVSRKSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAV4</accession>
    <name>A0A423UAV4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006347</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000181">
        <property type="protein sequence ID" value="ROT85805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAV4"/>
    <dbReference type="OrthoDB" id="6344823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="133" mass="15266" checksum="B999DE6A7D88326D" modified="2019-05-08" version="1">MHVNTHTGARPFTCDVCGKGFMRRTTLNAHRPIHDASQFSCPTCNCPFKRSSERLIHILLKVCLRKQRILRRATGGWFCDVCNEGVPQPEEHRCPVKGRRRQCPVCGMDFGGQRDHKMLTHVRQDHPEFLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB40</accession>
    <name>A0A423UB40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000159">
        <property type="protein sequence ID" value="ROT85885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB40"/>
    <dbReference type="OrthoDB" id="6372208at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019539338" evidence="1">
        <location>
            <begin position="18"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13867" checksum="D91CE6EFDAA0A66F" modified="2019-05-08" version="1">MHFSLLTAALMAAVVAAAPEAQYGYQAPKCQPEIQYVTRTETVPEYVTTTHYQTHTQYQTQYQPRYVTQTQQVPHYVTRTQTVPEYITQTVPQYVTRTQYQTQHVTVTKPCPSSGGYGGYHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWP6</accession>
    <name>A0A3R7LWP6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Low molecular weight phosphotyrosine protein phosphatase</fullName>
            <shortName evidence="7">LMW-PTP</shortName>
            <shortName evidence="7">LMW-PTPase</shortName>
            <ecNumber evidence="7">3.1.3.2</ecNumber>
            <ecNumber evidence="7">3.1.3.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Low molecular weight cytosolic acid phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015444</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="7"/>
    <dbReference type="EC" id="3.1.3.48" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01002922">
        <property type="protein sequence ID" value="ROT66518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWP6"/>
    <dbReference type="STRING" id="6689.A0A3R7LWP6"/>
    <dbReference type="OrthoDB" id="3388at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004726">
        <property type="term" value="F:non-membrane spanning protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000105">
        <property type="entry name" value="Low molecular weight phosphotyrosine protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002115">
        <property type="entry name" value="Tyr_Pase_low_mol_wt_mml"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00720">
        <property type="entry name" value="MAMMALPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="8">
        <location>
            <begin position="8"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="17913" checksum="BFB86E91084D977F" modified="2019-04-10" version="1">MASGAEAKKVLFICLGNICRSPTAEAVLNHVLKQRGLEGWEVDSGAIGSWHVGLGPDRRAVNVMKRHNIPMDHKARQLTKEDFNHYDYIFGMDHENISDIKARAPKTYTAKIELFGSYDPKKELIIRDPYYDDDDKGFEKCYEQCLRCSEGFLDSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXD6</accession>
    <name>A0A3R7LXD6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phenoloxidase subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014890</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002862">
        <property type="protein sequence ID" value="ROT67044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXD6"/>
    <dbReference type="SMR" id="A0A3R7LXD6"/>
    <dbReference type="STRING" id="6689.A0A3R7LXD6"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF4">
        <property type="entry name" value="PHENOLOXIDASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemocyanin C-terminal" evidence="3">
        <location>
            <begin position="5"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25765" checksum="4B805B6EB577CAC9" modified="2019-04-10" version="1">MTQPPYTPDQLSVDVEVMEVAVQEDNGTLNDLHTFFTEDTFVASHGMDFHLDPESNITVLYTSDFLNHTDFTYNITVNNTKSGFMKPKVRIFLAPKYDENGLPLTYASLLQYWSRWTCSKQTRLNLAYSTITRRSSDSSILSAYTGNNANFSFSGCSFPRHLLLPRGKPDGMTFRLFVMVTDADEDRAFGGGEDDPPSFCTFCGIPGAPYPDRWPMGTLWRERACTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYD5</accession>
    <name>A0A3R7LYD5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chaperone protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019744</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003696">
        <property type="protein sequence ID" value="ROT62401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYD5"/>
    <dbReference type="STRING" id="6689.A0A3R7LYD5"/>
    <dbReference type="OrthoDB" id="6343681at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053025">
        <property type="entry name" value="Mito_ATP_Synthase-Asso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44873:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="60"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="236" mass="27174" checksum="1CD6A2293D726039" modified="2019-04-10" version="1">MTSLICRTEVKGALNSFARNSFKRVLLENSRPTLVGGIGLHPGTPNQQKAWISSIPKKRSYYETLQITPKATQSQVKKAYYKLSKTYHPDQYRGNEDAALKFREITEAYEILGNLKKRRMYDKGLLNMNVAVSPAEAEEYSSKFYESRSKRGKAPTATGRTPIYDFDEWSKLHYESSFARRENAKVRYERMQKSRTDIVEEKKAESVVYILIVAIVLYCIKVSFSSTSDHDKVKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYM3</accession>
    <name>A0A3R7LYM3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein disulfide-isomerase</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015143</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002885">
        <property type="protein sequence ID" value="ROT66800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYM3"/>
    <dbReference type="STRING" id="6689.A0A3R7LYM3"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000030">
        <property type="entry name" value="Protein disulfide-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000042">
        <property type="entry name" value="protein disulfide-isomerase A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF240">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="327" mass="35850" checksum="087E6B76B3A22D7F" modified="2019-04-10" version="1">MVWTLQGSCPEYAKAAGKLAEMGSAIALGKVDATEETDLAEEHGVRGYPTLKFFRSGKSVDYGGGRQADDIVNWLLKKTGPPAKPLATVDDAKAFIAEKPVVIIGFFKDQQSDAAKQFLAAASATDDHPFGITSEEALFTEYGLSADGIVLFKDFDEGKNVYEGEVTEDGVSKFVAANSLPLVVDFNHETASKIFGGDIKSHLLIFLSKEAGHYDTHLSAATAAAKGFKGEVLFVTINTDEEDHSRILEFFGMKKDEIPGLRIIKLEEDMAKYKPTLMTSVRVGLSALSRVFLDGKLKQHLLSQDLPEDWDKSQSRFWYPPTSMRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZ71</accession>
    <name>A0A3R7LZ71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002831">
        <property type="protein sequence ID" value="ROT67227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZ71"/>
    <dbReference type="OrthoDB" id="6376450at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="354" mass="39529" checksum="610B9E05E5DC0402" modified="2019-04-10" version="1">MARAQSQSPRPITHARRLGTADEHLSAPSASTTVAKARRVPGASPAQSGPPFFVTRSSSPFSLTFYLFPFPTLSSLLPSLTPRPVSLLSPSLPPFPLSIFSSPFPFTSSSSPPFSLPSSPSSRVPSPPLPLKPGCFTNQIPSGTSSCLVLPSWRRNRARSLEFLTLGLLLSRALRLGRCSPRARPYAFNTDYYLNLSKSSGSTIESEKVEVTNQSDAQSLVERRRCWLVDPVWYPNPWAWDSIWVPPHENRSQPHFGYEAYRQLILKYLELRNRKYTVVLRLCPLHQHLLDDGNGVKQEPRVTLAALHPYRLPVEDVRVPPHESSEWPSSVPHFNLVSSYDLMVQFLGIGCKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1A9</accession>
    <name>A0A3R7M1A9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002459">
        <property type="protein sequence ID" value="ROT70152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1A9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="74167" checksum="B81239A56E3C98A4" modified="2019-04-10" version="1">MSSTVKAAVSLPVSETKTRNRKRERPKTTNRNNEPKTAQRNNEPKQRTETAHRNNEPKQRTETKRTSPKQRTETTNRNNEPKQLTEQRPKQSNRNNEPKQRTETAPPKQPNATEPETTNRNSSNNERNNEPKQLTETTNLNHRNRTETETAQRNNEPKTAHRNNERNSSPKPNNRPKQLTETTTNRTETAHRQTTNRNNETEKTQLSPKQRTETAHRNNEPKQRTGNSSTETTNETAHRNNEPKQLTETTNRNSSPKQRKPKQLTEKQRNRKQLTEKQPKQRTETAHPKQRTETAHRNNEPKQLTETTNRHTENNEPKQRNRNSSPNEPNRNKPKPKQTTNRNNEAETAQTETTNRNKRNQNNEREPTTAHRNNRTRNNEPKQRTENSSPKQRTETTNRNSSPKQRTETAHRNNEPKQLTETRTETAHRNNEPKKKLTETSHRRKNLTEKAHRNSSTKQPNRKSSPKHLTETPNQKISPKQLTETTNRKKAHRKHQTETTNRTTEPPRPDLDTAKRRSPYVTILALSLVTIRPLPSSSSSSPSLSSPYVTSSPSHLSSRHHPRPLSRHHPRPLSRHLRHHLVPSSPSLSSPYVTILALSLVTIRHHPRPPSRHHPRVRFKAACFILRVISFSSWLRPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M262</accession>
    <name>A0A3R7M262_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002377">
        <property type="protein sequence ID" value="ROT70870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M262"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="138" mass="15006" checksum="6779522AD91361E5" modified="2019-04-10" version="1">MRSRPPLFFALPSTGFLLQFSRGSLLRSPPQVLLRHKGLTRPLGAIEKLSSLASEPPRAATKGRGGGHRPLRPRVEQSGHQNPGHLQGSPGQGNRRALMTFDTLEGGAVMHSVVVEARESKKPRLDAWCSSIVLVVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M523</accession>
    <name>A0A3R7M523_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Pyruvate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014531</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002816">
        <property type="protein sequence ID" value="ROT67377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M523"/>
    <dbReference type="STRING" id="6689.A0A3R7M523"/>
    <dbReference type="OrthoDB" id="420076at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="96"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="719"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT67377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="740" mass="83314" checksum="91699D7572CAABC9" modified="2019-04-10" version="1">MAKVFTSFSQNVRYLTRSFEPRLLAADLGGQPRSKVTTCLFSTCRVDRTNTSYPRPRLSPQEVSTILRQNEGMIQLDSGGTGWTEQGYTSSGSYSIDSVDSNQLASNSPIEDKLASARCLHTTGYLFGVFDGHGGPECSQVVAKRLFDYVAAALLPRKELRRVVSEWEAGNRIPLIQVYNDPSQFVSELQEIYQDSFLRYCISLLSAFDEDFSMEEVLIQAFTQLDNDMGREVKENQQSAVLEPLLRVALSGSVACVAHIDGPHLHIANTGDCGAVLGMQSQTAGSGWRALRLTRDHNWENPDEIERVLSEHPDSESEHVIVDQRLLGVLMPFRAFGDFRFKWDLVTQSEIIQRYLGPEHLIRHCVTPPYLTVTPEVTYHRLRPRDRFLLMGSDGLWECMSPLDTVTLVGEYMSGRQTLQPVRFPRQAITLREVASILEQRQKGLNLKPVDTNASTHLIRHALGGSDAGLDHARLSHSLTLPPELVVLNSEGHDYQLEVPTGTTVERIKTMAIGHFFNPLELEGISVTDDKGDTSKTGNKSRTYRLVLEQERIRCEELFQYHWNREKQRKEQNELLLVDGREAPPIREPAPEEMTIPTMREIAEATVNLAKRNHNRDPDPMNHSTDLVVLNSEGHDYQLEVPTGTTVERIKTMAIGHFFNPLELEGISVTDDKGDTSKTDELLLVDGREAPPIREPAPEEMTIPTMREIAEATVNLAKRNHNRDPDPMNHSTDVSLDFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5R0</accession>
    <name>A0A3R7M5R0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008858</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5R0"/>
    <dbReference type="OrthoDB" id="6345588at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="332" mass="38318" checksum="EFE17F5003B061B4" modified="2019-04-10" version="1">MSVDTEPLEFDSMDLLSLYTVMAVKRLVVSKNPVVEELKKISDVAERNITRLNINRKWFFEVLRDHARLYEEEWSHALGLEGMGSFCFNTYLLVVSLRLGMEKIWDSEEFQIHEEEELKDILEKLCPKLPLRELNQLYPMFEYYAQKSPNLEVVHMPRSDNNSFKRVMAYRNLRVLTLAGGVSDKVLCNCLWGIDKRSDKVLDLVLKGTKATSSVQLSLPHLEVLRNNIRRKNSNTMRVSLGAVALVLQPKLEEVETLEYWDTYDAVLYLLTMEDKYKTTTSSTRKLNVKCLPVDNRTYTGSGLRRVIDACPLFDYKYHLAIAIKATGSTSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7V7</accession>
    <name>A0A3R7M7V7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001897">
        <property type="protein sequence ID" value="ROT74444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7V7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF1">
        <property type="entry name" value="FH2 DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="44404" checksum="91AC825899EFB179" modified="2019-04-10" version="1">MTSRTFHIPRGDDDVLYHHTSPPGKSGDLASFIIFQGVYTVAPKPASRSASGTSDEAHGWETLGVHSPPWFILCPRTPPSPSPSFLKQLKPTLASPFPSLLFLLDILPFLPSNSYRSLLTSLQLSSVPSLSFVDVWLAPPPFLPSWAGSSPFPSISLAGWLLPFPPSLTGSSPFPSISGWLLPLSLHLWLAPPPFPPSLAGSSLSSISDWLAAPPFPSISGWLLPFPPSLAGSSPSLPSLAGSSLSLHLWLAPPPFPPSLAGSSPFPSISDWLFSLSSILISGWLLPLSLHLWLALPLSLHLWLAPPLSLHLWLAPPLSLHLWLASPFPSISGWLLPLSLHLCWLLPLSSISGWLLLLFPPSLAGSSPFPPSLAGSSPFPSSLAPSPFLHPSAPSPPLPASEIRYYARTYTSTKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9F8</accession>
    <name>A0A3R7M9F8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_011000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002397">
        <property type="protein sequence ID" value="ROT70701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9F8"/>
    <dbReference type="OrthoDB" id="115198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000001">
        <property type="entry name" value="Hexosyltransferase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF376">
        <property type="entry name" value="HEXOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT70701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="844" mass="96883" checksum="4779B6909D73191B" modified="2019-04-10" version="1">MAVGDTDRQKSLDNGMSRGKPTKMARKSHRSSYLRDTGVGLRADASKASERPEKVPNAFLIEEADFCRRRPRLQVIAYVHSAISRVQERRETRSTWANATASGLGVEIAAVFMVGRAKNQRERQIVQEESQRYHDIVQGDYVDHYRQLSLKALSSLAWVQHHCPQVPWTLHADDDVFIDVFLLKSILEDFRAETTKAFLCNSEWSLAQRAGRWAVSRDEYRNNEYPVFCTGAAWVLPTRLLPRLLRASQTAPFLWVDDVYITGVLAEHAGVTHLGTVYKSKHIQPSDVGDDWAKRDENWISEPSRPKAQVFLIEEADFCRRRPRLQVIAYVHSAISRVQERRETRSTWANATASGLGVEIAAVFMVGRAKNQRERQIVQEESQRYHDIVQGDYDDDYRLLTYKGLTALAWIAKHCGRVPWTLHSDDDTFIDIFTYVQRLEALDEASKERLICNHKVEPVLRTGRWRVNEWEFPDAEYPTYCSGGAWFLRTKLVPRLLDACRTVPFLWVDDVYITGLLAREANVGHFNGGGHCFEALNPADIGKMLVCQLQHKRNTSQEEETEALSSTNVPKTFQIEADFCRRRPRLQVIAYVHSAISRVQERRETRSTWANATASGLGVEIAAVFNVGRAKNQRERQIVQEESQRYHDIVQGDYVDSYRKLSFKALASLSWITQHCPDVPWTLHADDDVFIDVFLMLEYLREENPQGFFCNVMWSQVMRSGKWAVSRQEYPSDKYPAFCSGEAWVLPTALLPRLLEASKSAPFLWVDDVYVTGILAQYAGIAHLGIGSESRHIRPSDVGRVMAWHSLEDDRKKWWTILTRVYKKALQRSKERVSDETPRGKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCM3</accession>
    <name>A0A3R7MCM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001400">
        <property type="protein sequence ID" value="ROT78308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCM3"/>
    <dbReference type="STRING" id="6689.A0A3R7MCM3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="772"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="795"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="922" mass="103123" checksum="E1813E34C698C2C8" modified="2019-04-10" version="1">MGNCFKKWMTVTYWLRQHGRRIVITAAAVRSGPHLSPVCLATQHNNPTTSNHPKTTPHTQLKTQHQNTTTHSHNSHIRSLNARPPPTPVHSPPPSLNPYPPRNPRTTEPRPNKKINRFIFQSENTRPDPTLTPWTRPDPKPTRTRITTRLDPNHNPTTRRTRIQTRPTRNPNHNPTNSKDSNHNPTTRTTRITTRPDSKRPESQPDPTWIDTTRSDPDPEPDSTRIRPTRSQDDLTTRSNPIRKKLTRPGLESYPNHPDTTRSHPNPSRPKPNPSLTSKLPLPDPVQSAHNTSLSPTQSDLTRLSPRPKPTLTHPTELSPPTPTYPSLSPTRSDPNSPNRPSPSDLPVSPTNPTRTLPAKPTLNPTTPSLSPTNPTRTLPDQTDLNPTYPVSLPDQTDLIRPTPSLSPTDPTELSPTKPTLIRPYPVSSPTRSDPTLPTKPTLIDLPRLSPRSGSDPKLSPTKPDLNPTPTHPTQLSPTKPTFPTYPLPDQIHPELSRPKPFHPTYPVSFPDQIRPELSRPNHLNPTYPVSFSPTRSDPNSPRPKPTLIRPTPSLSPTRPNPTYPSDPNSPDQTDLNPTLPRLFPDQSHPTLPDQTDLTTYPVSFRPDPTRTLHDQTDLHPPTPSLSPTRSDPTLHDQTTLHPTTPSLSPTNPTRTLPDQTDLNPTYPSDPNSPHQTDLNPTYPVSLPDQTDLNPTYPVSFPDPRTLPTKPTFIDLPRLSPTRSDPNSPDQTDLIRPTPSLFRPFRPGPTPSLSPTRNPTFIRPKPSPRPNRPSSDLTPSLSPTRSDPNSPRPNRPSSDLPRLSPHPIPTRTLPDQTDLHPTYPSFPDPRPELSPTKPTRTSLSPTQIRPNSPRQNRPSSDLPVFRTLNRTPYPVSFPDQIRPELPRPKPTFHPTYPVSLPDPIRPDPDPRESDREGNIFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCZ3</accession>
    <name>A0A3R7MCZ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycine receptor subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_008443</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCZ3"/>
    <dbReference type="OrthoDB" id="6351594at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT73127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="59522" checksum="BD748912B14AFF6E" modified="2019-04-10" version="1">MNDEIRAEYFYLVPHRRKPRYLSLFGKVIQEKEERNLTLTNEEKEVVGSAVFKGPLPVGRFEWSFSRLGGRNMTLTACSKDQFTCSNGLCIPLENRCNGLEDCSDSSDEICSLLLPLPDTYQQQRPHRFFTDLNLTVDLMEILEVDVYGSIFRAKMKVLQSRHWRDSRVLLFQMSRIGSDNALDQDVLWTPTPILLNAVFSDEKSHLTGEGKLSSLRAYRDGPGVAVTRNAFEGYEYSSSSAYLELVEVFEATFKCRFQLDLFPSTSTCAMLNFSLNVSGTPQTPELPLFTPSRVCYSPEFSENGNVTVVSFKFQRRYGSYIFTTFGPCLMLTLIGYLTLFFGVDNFSDRIMVTLSSLIVVASLFAQIATTTPASASPKVIDIIFLAIIIRLFFVVLHHSIYYLLRVYVKKCEEKRSRDAVQPLAVRKWAGASAELPAVYTPPDVKLRKMPWEKSDEEGDKEPKNQWKNSKCVSECDKTFNVLGIAVGLLWDVLWVSLVFLYILQTRSEIFQDFEECLTEADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEM6</accession>
    <name>A0A3R7MEM6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001200">
        <property type="protein sequence ID" value="ROT79699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEM6"/>
    <dbReference type="OrthoDB" id="10628479at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="219" mass="24238" checksum="CC633F6D21287EA9" modified="2019-04-10" version="1">MELKNVYERYQARLRNSAFLGVVSIGALASCCLLGTMLHGSQSYEWSPAAVILCCYLGFLLLIIGMAQQVFTANISVISAILATTFWLITASILVSVGILHQPKSSAHLTPPAFLLVLITHTTVPLRRAHTRILAGISTLLPLVTMLASPALTWGVRQEPASVTSSQSKLFKLQWNFGNCGRGRHEAKKWRKERAGSFGKESHECEQQFPRMILTEEWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEV9</accession>
    <name>A0A3R7MEV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001095">
        <property type="protein sequence ID" value="ROT80648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEV9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="42700" checksum="29C0E76688FE67ED" modified="2019-04-10" version="1">MHKSHTPILTPTPLTPCLQKSIKRPIIFSDSTTLSTEERGKGNTPPLPLHPPINKKILKITPPLPPLSIIAPSPHPTAPISLVSPHLPHLLLSLIPLFSPPPFPSPFSHLPISLPSIPSPLPPHLPILPPQFFLHPPYPFHQPPSPPFPHSPFSPSTPSIHPIPLPSPNPYPLRTIHPIPLPLPPPPNPHFPLRPSTSPPSATTPSNLLPHPPAGPLPLPQTSPSSLTLPSLPPTPSPTIHHPSPPFPPLNHPPTSPYPPQPPSPITPFSNPYPLPHNPPLPTPPLPPTSPPLPIPFLPLPSPFPPPKPLPPPPPFPSETLPLPTPHLPSGSESHRRHLRTSTNCCHKSLTTFGCHEIEIKLEATLSFSRPNSRWFGGGGGWGGGGGGWWWGGLGVWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIA1</accession>
    <name>A0A3R7MIA1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000822">
        <property type="protein sequence ID" value="ROT82436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIA1"/>
    <dbReference type="STRING" id="6689.A0A3R7MIA1"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000166">
        <property type="entry name" value="Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF19">
        <property type="entry name" value="KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="5">
        <location>
            <begin position="86"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="50811" checksum="76DAB797CC5DD368" modified="2019-04-10" version="1">MTRRCRFPGIRLVSAPLLRGRMDYSRFLSTNAKTRKPSWITQLRSYLANPSSDILWLAGGHPDASLFPFKETTITLKNGQEIHLNQDLMATSLQYGPIEGHTPLLKYLADLTQKLHSPPRWSETRQLVTVGGQDGMAKAFVMLTDPGDYVVVPEPCYAGIFSELTSLNPHYLPVEEDEEGMRSDLLRSALARWKSEIGETHSEKRLKFMYTNPSGSNPSGTNMSEKRRREIYALACEYDFLILEDDAYYFLQFQDDFPPSFLSLDTEGRVLRFDSFSKTVSAGLRVGYVTGPEFLVEKISQHIMATVMGGSSLSQVLVTELFHMWGLEGFLRHVKEVRDMYRRRRDAALSAAEKHLTGLCEWRKPGGGMFLWLKVPKVKDTQAMLLERGTKKSILLVPGNGFTTRPELPCQYMRASYSTVLPEEMDKAFQILAEVIRDEIQLNNEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJQ9</accession>
    <name>A0A3R7MJQ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000669">
        <property type="protein sequence ID" value="ROT83571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJQ9"/>
    <dbReference type="OrthoDB" id="6618089at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="583" mass="66161" checksum="441422E890DEB53F" modified="2019-04-10" version="1">MFDGIREWAIFKTLLRRKFRGTCSSTDFFTILNECRMTTTQGPQDFFQQLEGIVYQGVRDYPDVVGNPEPLLKRLFLQGLPLWLREYLAIIDELPLDRLVETAQRIWNTRTGVARTEPLADRHPPRPLRAVAPVEEPPEHRRTRWCSYHRTSRHDNTECRYRPRRLACFRCQQEGAPVAGGTRWGQPLQYPRSSDTGAIGRNSLNPHLQPTSRTTDGGFKVPQEHRLQSQRLDFRLGYDSRTNNSYLRLRGKAFTVRYVNKDSLELTAVVMKMKGISASATARAAIRRSVSCPPESGRFVPVRVPDALIGKQLLVEGLGYSVILPREVIKPSSKEAVVWVVNPTLNPVKLRNGTHLVELHEVEEMCDTPEAPGNVASIADTPVAAVPTSDKFAIGEVPDIVHEIPTQEKHPLCQRQWRLPEAAKRHIPAQEASRKARQEYAAYHNRNLRPPWSLEAGSLVLYKIKTTQTGPDRALGPRWQGPAKVVKKLGPVNYVVQDLSPPFSERNCHANQLRPFKLEEELTFPDASPYHDPDYVDPWLPDDAEPDHSNTSTSCGLSSETDVARTTNHTWNYRSAQDHRFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJW9</accession>
    <name>A0A3R7MJW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative leucine-rich repeat-containing G-protein coupled receptor 6 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_022104</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000508">
        <property type="protein sequence ID" value="ROT84704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJW9"/>
    <dbReference type="OrthoDB" id="1883493at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051432">
        <property type="entry name" value="KCNMA1_auxiliary"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46473">
        <property type="entry name" value="GH08155P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46473:SF10">
        <property type="entry name" value="LD45603P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT84704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="26536" checksum="89E0EA6CCCB8E0C0" modified="2019-04-10" version="1">MECTEAGLSSVPLVEALGDLDPAAVTSMDLSNNNLTSVPDNAFAAYPSLQYLRLSGNRISSVSPQAFEGVKLQNLMPTPSPHSGMPPPLTHSFIPYLPSLDISPPTLRHAKTYPVGHTPFLHTHFPPLSRHAHPSLIPASPPAPALSRHASCSPESFPFLCISTLPSQPAVQAGLKKKDVSSSPPSVDKSSACGRVASFSSFRRYLDNNQLVGLVAGSLPDTLAELSLEDNFFITIPPAVSLIRDLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKE4</accession>
    <name>A0A3R7MKE4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_022683</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01000591">
        <property type="protein sequence ID" value="ROT84107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKE4"/>
    <dbReference type="STRING" id="6689.A0A3R7MKE4"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000124">
        <property type="entry name" value="Cyclin-dependent kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000061">
        <property type="entry name" value="Putative cyclin-dependent kinase 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF128">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="94"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT84107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="47473" checksum="10BE38E503A6ED84" modified="2019-04-10" version="1">MLHKSSTFSSFTSGTAKIGSWFSHIGDRRRKTSANSVLKTSKSLQLGVVHEVPRIGSDGESEEASGASDEVTSPVNVKLRQKNRRITQEDINKRLSLPADLRGTYATVYKGRSRLTDALVALKEIRLEHEEGAPCTAIREVSLLKELKHANIVTLHDIVHTDKSLTLVFEYLDRDLKQYMDECGAQLSMNNVKIFLFQLLRGLAYCHQRRVLHRDLKPQNLLINDKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTQIDMWGVGCIMYEMISGRPLFPGATVEDELHLIFRTLGTPTEATWPGISTNEDFNQYSFSSYAGEPLLARAPRLAHDSAVGLLTKFLLYEAKKRISAAAALKHSFFESLGHTVHTLKDQDSIFSCPGVMLTRDHNYKVTNGSQAKTRRQSMHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLM4</accession>
    <name>A0A3R7MLM4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003170">
        <property type="protein sequence ID" value="ROT64910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLM4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="702" mass="80362" checksum="0996A1AFB4BF70EA" modified="2019-04-10" version="1">MTPTLHSNKTSNKARLFWLAHIQTPSPPPPSITSFPSLSFYPLLPSSLSTPFSLPPPTLFLTLLFPFPLLLPSSSPLSTPFSLSLLLPPFSLPSPFSLSPFYLISLFLSPSTPFSLLSFYPLSPLPLLLPLSLSIYPLSHSLSFYPLSLSIYPLSLSIYPLSLSIYPLSLSIYPLFSLLSLWLYKTSNKTSNKARIIYLPRREYSTRPVLCKARIFHSKVCLFHLSTYRHVVTYSPPHPSTTSVNSHLPYVSPTCIIYPSTYCHLRCQTSPAGTLHHSIIYPSPTLSTWAHPQNHLFRPYRSPVRHLQHLHITCIYHLRSLPGTPTLHLSHHFINDPLSLHLSYHLTPSIRHLHHLSDLHHLPSRHCSSPPHSLITTPHLTRHLHHLAHQPHHTSHLTTTWIITHPHYTIYNYTTWLITTPAPHLHHYPVTYTTWIITHRTYTIYPVTYTTWLITTPHLHHLFVNYTTAPSSLTYTIYPLITHLTYTNLTPSIVTYTTFITITHLTYTSIPSPHTLHHLSLTYTIYPVTYTSCSSPHRTYTIFTPTHHPPHHLSPHLHYLPVTYTHLPHHHTSPTHLSPPIYPLTYTIYPVIHPSPTLTRTYTIYPLTYTIYPVTYTTWLITTPHLHHLSLHLHHLTHHHTSPTPSIPHLHLPTPPWLITTPHLHHHPTSPTPSTLTSPSSSPHLTYTSWKSSWDVCKFLGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMB5</accession>
    <name>A0A3R7MMB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ryanodine receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000259">
        <property type="protein sequence ID" value="ROT85518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMB5"/>
    <dbReference type="STRING" id="6689.A0A3R7MMB5"/>
    <dbReference type="OrthoDB" id="300855at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034704">
        <property type="term" value="C:calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033017">
        <property type="term" value="C:sarcoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005790">
        <property type="term" value="C:smooth endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030018">
        <property type="term" value="C:Z disc"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005219">
        <property type="term" value="F:ryanodine-sensitive calcium-release channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014808">
        <property type="term" value="P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006941">
        <property type="term" value="P:striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015925">
        <property type="entry name" value="Ryanodine_IP3_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399">
        <property type="entry name" value="B30.2/SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46399:SF8">
        <property type="entry name" value="B30.2_SPRY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="347" mass="38272" checksum="10A407047B698D7F" modified="2019-04-10" version="1">MTLIMPTASSRNRAAVMPEASAGGGKVKKKKRRADGKKMSKEKELASSLMVACLKRLLPVGLNLFAGREQELVQHCKEKFLAKVPESEILVFAKTQLTLPDKIDPSDAMNWQHTLYSRLGGGRVPREDDEEKKLVPSVDETVDNIVAMAKVLYGLHIIDHPQSSKEVWRSVVSIQRKRAVIACFRQTSLHMMPSPSPTRFSRSPPCSQISPPPPPPCCVLSGRVSSHKLTLLVADLRAVSLPSVPLLRPPSLREQMLRGGPGGVLAGAWRPWAGERREAACTPPVSRSGWRKLLSFARKRAAIACLRSVPFYNVRRLYVSITDYDLASSYQTKTLSHPCDVALGVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSN8</accession>
    <name>A0A3R7MSN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000469">
        <property type="protein sequence ID" value="ROT84929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSN8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="42618" checksum="756BCC8248348BB7" modified="2019-04-10" version="1">MLPESLFLSLVLFYPSPSPLFAPPFLSSLLSFGHPFPLPFHFPSSHPLPLPSPPFSPPSLSPSPPPSSSLAPPLPPPLPFSASSPPPPLPPPLPLPSHSLHLPPSPFPPPFPSSTLSPLAPLSPSTALPPPPPPSTASHPLPLPPSTALFIGVVLKFSFNETWVEARSDSPASSGGSLRSGPPPLPTSFVSPPPPLPFLRYPLLLLPLRYPSPTPSLSLLLPLLLLPSLSPPPPFLRYPSSSLPFHRYPLLLPLLPSLSPLSSSPLPSLSPPPLPPFVIPSSSSPFPSLSPPPSSPLPSLSSSSPPPFIPPPSSPFLRYIPPPSPLPSYPLPPLPSLSPLLLPPSFVIPSSSSSLLRYPLLLSPPFVNPLSFRYSLLLLLPPSLLLPLPSYSLLLFPPSPSIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MTQ4</accession>
    <name>A0A3R7MTQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(A)-specific ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000206">
        <property type="protein sequence ID" value="ROT85709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MTQ4"/>
    <dbReference type="STRING" id="6689.A0A3R7MTQ4"/>
    <dbReference type="OrthoDB" id="1432093at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="255"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="36042" checksum="C1D5B056ABC2A08C" modified="2019-04-10" version="1">MADETRDVLVIPGSTLTGFFRKILYNNIASKYQNILIRNVTTEGWLHSCCPERHIESGKTLVGHNLVLDLLHLINKTVHPLPEHFDNFKTLVKNNIPTVYDTKLLAKDPPFCVDIPFTALGSLYKDLREKYEPPTFAPEEGYASHSCEEDGMAHNAGYDAFMTGVCFVTMVKKLDGMNWAIHPNRGHIFSVECPSSWTPMHVHGLFHMLKSLKIIWMNSTHLYVIPIEEIDSTMCRRLLKTVRASCPPLVRVRMYDDRPTPKRKSESDDASFTAIGSSDHPKEFKRLKSVGSDQLSQMSLESPVEEDPPAVICDQEGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N2L2</accession>
    <name>A0A3R7N2L2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal protein L7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001759">
        <property type="protein sequence ID" value="ROT75553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N2L2"/>
    <dbReference type="STRING" id="6689.A0A3R7N2L2"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_uL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="6">
        <location>
            <begin position="45"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="121"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="278" mass="32272" checksum="A7C0BFA28E6D9FBA" modified="2019-04-10" version="1">MADSAQKAAPAAARPPKRREPKTLPDGTRKPNPYKVEKKRRLPAVPEVVLNRRRDRRAHKKKSLALKLKAKADKRKLRQKYFTRAEAYIKKYRTMEKEQLRLKREAKAQGTVLVPAEARLAFVIRVRGVNQIHPKVRKVLKLLRLLQINNGVFVQLNKATLSMLRIAEPFITWGYPNLKTIKQMIYKRGHAKIDGRRVPLYSNTLIEKYLGKYGISVLKTWSMNLHPGKNFQKVNNFMWNFKLNNPKGGWRMKTKHYVEGGDFGNREGKINALLAKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N3G3</accession>
    <name>A0A3R7N3G3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001675">
        <property type="protein sequence ID" value="ROT76295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N3G3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="46839" checksum="149B22F18FC83B22" modified="2019-04-10" version="1">MISRPSLTTGSHNNFTTLHNPSQPLTTQELHNLSQPFTTPHNPKNFTTLHNPSQPSQPKNLQPFTNPHNPRTSQPFTTLTTFHNPSQPSQPFTALHPHNPSQPFTTQELHTPRTSQPLTTFTTFHSPSQPFTTLHNPSQPQELHKQPFTTLTTLHNPHNPFTTLTTPHNPHNPSQPPHTILTIFSLKNGGSNPSLAPHPPLIFLPPSPRRPSLSLLILIVYRLLPFPLSFLPLLSSSFLPLSSLLSSSFLPLLSSSFLPAGAVIAIPLNERTPESPPPEPSSGGTGTEEEVVPPRSIPPPSRAAEGRGPEEEQRRRSSPEVHPPPPEPSSGGTGPGGGGRPPRSIPPPRAEQRRDGGPEEEVVPPRSPPPEPSSGGTGARRRRSSPRGPPPPRAEQPRGRSRPPRSIPPPERAAEGRGPEEEVVPPRLAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NUS5</accession>
    <name>A0A3R7NUS5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cGMP-dependent 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002829">
        <property type="protein sequence ID" value="ROT67250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NUS5"/>
    <dbReference type="STRING" id="6689.A0A3R7NUS5"/>
    <dbReference type="OrthoDB" id="295473at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="314" mass="33883" checksum="143DF2B275F34A27" modified="2019-04-10" version="1">MYSFVNNNSFSTALTSRRPITLDDIEPSHREDVWRLLGLLPGGDRGVKKVDPLQHKGPSRTNNGQASTGLGATKSLEGGAASTRARGGLMRDMSVDLTRDSSPVSSLTSTPLKQDALKEAQGKEEEGGGQWAHGSLPAASLTPLEGSAVSNHKHGVRRHHQLVSYTSLPFDGAGGGRLGGGIGSLALDPTFSPASLLCVPVACPGKETLAVLACLVDKTSEMEFDQEDVLTVQECFKYTIGMLVNTLTAEREHRLRTQCQALLNVAQNLFTHLDDVTVLLREVMAEARKLTDAERCSSSSWTRTTISWLTWRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NWP5</accession>
    <name>A0A3R7NWP5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FCH domain only protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_012990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Clathrin-coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002627">
        <property type="protein sequence ID" value="ROT68839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NWP5"/>
    <dbReference type="STRING" id="6689.A0A3R7NWP5"/>
    <dbReference type="OrthoDB" id="5593455at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018808">
        <property type="entry name" value="Muniscin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF15">
        <property type="entry name" value="AT02057P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10291">
        <property type="entry name" value="muHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0168">Coated pit</keyword>
    <keyword evidence="2" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD" evidence="5">
        <location>
            <begin position="344"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="185"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="254"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT68839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="626" mass="66710" checksum="588741A09DB47774" modified="2019-04-10" version="1">MLNSNKEEKSDNEVNDDPGPRTSELISTSITQGGSDKTTGPLTTSVDEEGFSVRPQEIKTPAEETSFDSSSDSDSDGESDKKIHVEIKPISNGNTPMSASVDELRATIEGMSLSPMPFASPRVPPRQIYADGKIKIRYLTLQKTRRTSTDTQDSLPMKRSNSITHQLSNKTSSADLLGLNLTFGGSSGTSDSSPRGVLATSTVGDTAVNRPMSPASNALTGLSSPAPSVSSITSPVLAPPPRADRYAELSEILNETEGDTPPALPPRTGGGSSSRGSTPTPTMAIPRPPSRKALEGPSPRGRQSPATVSGLSRAESVSSLEFRTSSMVGTSRGPSPLTIGLSDTIPIAVAFQELCHAYFRGSDESKCQVKVTGEMMVSFPAGIVGVLANNPSPAQLSFRVNNFARVTNVLPNRQLITMDTEQSTEECGAFDFNMPALTALLRKQAESNPSASYFNVDMIKYQVNIGSGAQSSPLQLVSYWKCEDSHTDLRIDYKYNPHAIASPSPLLNLNIKVPVDGVVGNMQSKPSGQWLKDEQKAMWKMTELSQHSTGGGVGSLRAKFEVAAGPSTPATVSAYFNCEGTTVSGLEFSLFGSGYRVSLIKKRFVSGKYICDADAVLRLRYGSIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBI5</accession>
    <name>A0A3R7PBI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004646">
        <property type="protein sequence ID" value="ROT60659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBI5"/>
    <dbReference type="STRING" id="6689.A0A3R7PBI5"/>
    <dbReference type="OrthoDB" id="7587145at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006631">
        <property type="entry name" value="DM4_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41158">
        <property type="entry name" value="AGAP010294-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41158:SF2">
        <property type="entry name" value="AGAP010294-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07841">
        <property type="entry name" value="DM4_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018599937" evidence="1">
        <location>
            <begin position="26"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="291" mass="31397" checksum="5C7523D5F907DB5A" modified="2019-04-10" version="1">MVSRRMVGAALVALIASSFVSSAVAASMDAQEARKFAAKPNDIKKQQNFLPNNKQEQANDGGFQWGKILNMVMQIFIGGPTGGSSGASDKMDYITQLTTGEFSWSKVLALGLQVVLSVLGGGDNAALDRIDGGSPIEGILTAVISYLTGSSDPQEVGVMAKQATELFGLVVTLLDALRTSFSQRSFEARSMGTTDPMADAAVAATTMLKSYIKTYETEDDMCMQKYLCEANNDCVYSTGDTGYLFCQIGTYGMSYLLERTTYTPFEIYNDAGRRGRVGENCREIFSDCNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEE2</accession>
    <name>A0A3R7PEE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003498">
        <property type="protein sequence ID" value="ROT63072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEE2"/>
    <dbReference type="STRING" id="6689.A0A3R7PEE2"/>
    <dbReference type="OrthoDB" id="8854879at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="639" mass="66457" checksum="BDFF3D45BC0945B7" modified="2019-04-10" version="1">MFNFPGGPNGPPAPPAPSVPVSQFNSQFNGQFNAPGENGTAGYVPQGHFSPQTPQTSVPAFASGPPNGFLTQNQGNGVVGVSAPEASPVTGGFTMTTLPSPHAPHTPHAPHTPHTADHPNEKPGYPPPPPTQSLLGSRVSAGGYSGQTLEGGAGVPQASPHGSVSVQSRLKNMIMSRQGGSAYPGGGVDSPPLGEVHFSGHVAAVTSVANAEPAHMHESLKMAQNFLAYRTAEPGPGSVVHANSSDVKGGVGTGHTHANTNSSSEPPSTEGTPLRGSAPPQNCQVSEHTSSGNDHGNSEIDTDIKKEVIDDVEMKEELANVSDDVEMKEIEKKESEDVKINEEIKVERKEESQVDQAAACPTDSIAPKPPDQLGPRTPPAGASEDETGTRNTETSRPQNLGEKLSVYDFPDSPDSSQSRQDFRFGRVRGAGPPSSRPACASVPGAGRPGPLAATPAGPKTPSRHHVPAPPVCGGPPRPPGPPASAFQPCNESDSSQYSSNNTSTLANHTKTTPCQQVAASSTPGDQQSLQLQKQQANLHQSVGAVQPATYHPESHQSHVQQTQAEAPSASTHSTAPQTTPSQADASDGSRNTPRVKTEKGPKKNPDLEARKERLRLNELNVPRCSCIVPPGEYKALLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFG1</accession>
    <name>A0A3R7PFG1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002494">
        <property type="protein sequence ID" value="ROT69954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFG1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="39430" checksum="30BF6589130E360C" modified="2019-04-10" version="1">MKEWVRLFSDVVTRAFYGTRTPAATPASESSEDPVQQTPAASPALTAVPSLPTTGNAATGPPPPPLATPPQTPPCAPLGFPQSSSVPVTIPPSLPKDGQQGARQSSPAGAAQSLWSRFYGSAPPAQPQEKVVSDTGQERGRGRGRGRGGGRGRGRGASLEGGNGSPKLSKGNQHPQKPSPSASPHSARNSNSSVPPRPKRPGSWRQLPGALSRSLSPERPPAPQPPPVDEDGFTLVQRRSKPGRPPPSPRSNGASSQGEDTFYDAHSSYDAFTKDDFVLKKDDFPGIQKGNGASQRPGASRSRPATARQETVIEPGAAAQTMVLHRRRSPRNSQINPPRTKIEKCSLSVSRPPEINKKKQRIKRMKLKSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFJ3</accession>
    <name>A0A3R7PFJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative corticotropin-releasing factor-binding protein isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002468">
        <property type="protein sequence ID" value="ROT70105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFJ3"/>
    <dbReference type="STRING" id="6689.A0A3R7PFJ3"/>
    <dbReference type="OrthoDB" id="10056927at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051424">
        <property type="term" value="F:corticotropin-releasing hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009755">
        <property type="term" value="P:hormone-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051460">
        <property type="term" value="P:negative regulation of corticotropin secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008435">
        <property type="entry name" value="CRF-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056178">
        <property type="entry name" value="CRF-BP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10278">
        <property type="entry name" value="CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10278:SF0">
        <property type="entry name" value="CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23541">
        <property type="entry name" value="CRF-BP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018608335" evidence="1">
        <location>
            <begin position="17"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Corticotropin-releasing factor binding protein C-terminal" evidence="2">
        <location>
            <begin position="22"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="305" mass="32683" checksum="83185EC00F891C64" modified="2019-04-10" version="1">MALPLLLFSKLSSLSCNILVDDVSGLYTLRNHGRRSNCSITTIFPASVSIAQIAVGIKGSLVPNRAIETGVLSRCEKRGSRDYVQIGGAQGLDVTKLEVEDSVCGLDSNPRLPASHILCGMTTVRMVSSGLTDNSITLAISQISDFDIMPTLMCDLPLLRPPSFTVSFLPSQPVSRLPSEVLQKTSEPKLSFPPAPLISSPEDARPLRLRPLFVLVSSSSSLVHSSLLVSLRLSSSRRPLVSSLFVPLRKGNRIKTASAITYSFTHSSGRACGRETQSPGKTLDQPSCNIRSVHLVAGSLINASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PM10</accession>
    <name>A0A3R7PM10_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dehydrogenase/reductase SDR family member 6</fullName>
            <ecNumber evidence="6">1.1.1.104</ecNumber>
            <ecNumber evidence="7">1.1.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">(R)-beta-hydroxybutyrate dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">3-hydroxybutyrate dehydrogenase type 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">4-oxo-L-proline reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Oxidoreductase UCPA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Short chain dehydrogenase/reductase family 15C member 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_010828</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>(R)-3-hydroxybutanoate + NAD(+) = acetoacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20521"/>
            <dbReference type="ChEBI" id="CHEBI:10983"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.104" evidence="6"/>
    <dbReference type="EC" id="1.1.1.30" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01002377">
        <property type="protein sequence ID" value="ROT70860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PM10"/>
    <dbReference type="STRING" id="6689.A0A3R7PM10"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003858">
        <property type="term" value="F:3-hydroxybutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016617">
        <property type="term" value="F:4-oxoproline reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051122">
        <property type="entry name" value="SDR_DHRS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477:SF4">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43477">
        <property type="entry name" value="DIHYDROANTICAPSIN 7-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="227" mass="24786" checksum="E40C2FB3683987F4" modified="2019-04-10" version="1">MASSQTPAASSPGRLKGKRCLVTAAAQGIGRATVLAFLREGASLVVAVDINKEKLQTLEGIEGVLTKNLDVRDGVGIRALAQEIKDIDVLFNCAGYVHQGCILSTTEEQWDFSFDVNVKSMYHFIQAFLPTMLEKHRGSIINMSSAASTLRGIEQRTVYAPVATESYKERCQDLEDSDKDHIEYIEGKLMGRLATPEEVANLCVYLASDEASYHTGNVFTIDGGFCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMB9</accession>
    <name>A0A3R7PMB9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubiquitin-conjugating enzyme H1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_010502</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002333">
        <property type="protein sequence ID" value="ROT71170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMB9"/>
    <dbReference type="STRING" id="6689.A0A3R7PMB9"/>
    <dbReference type="OrthoDB" id="9993688at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14391">
        <property type="entry name" value="UBA_II_E2_UBCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000021">
        <property type="entry name" value="Putative ubiquitin-conjugating enzyme e2 k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042614">
        <property type="entry name" value="UBCD4_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="4"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="157"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="199" mass="22189" checksum="FA0E92AD16D9C2C1" modified="2019-04-10" version="1">MANIAIQRIKREFKEVIKSDEAQKCAINVELVGDDYRELKGEIAGPPDTPYEGATFHLEIKVPETYPFNPPKVKFVTKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVARQFKENHPLFLQTAQYWSHVHAGAPRGNSDFANKVRCLMDLGVGEQQALVALSSCNWDMDRAIEQLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNI5</accession>
    <name>A0A3R7PNI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002194">
        <property type="protein sequence ID" value="ROT72187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNI5"/>
    <dbReference type="OrthoDB" id="342730at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05819">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050952">
        <property type="entry name" value="TRIM-NHL_E3_ligases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24104">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24104:SF25">
        <property type="entry name" value="PROTEIN LIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="623"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="241"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="714" mass="79761" checksum="ECE765413B1C71F0" modified="2019-04-10" version="1">MPSEARRGERRCADCPRGAGIETKDRAVLDWSALLSKRVLKVAHVNAPQKRWERTLQLYDAEDDEDEYQPDFEERDDTSDVNSKANNIRATIPSPEIMKVRMILQAAKEENDEIDGKLRQRKQQVAIAERQTAELCAKKRNKESIEQWRIKESAPEESWKHDMYHQIYDRHSKLEDQPASRISAEELEESLLEYPEHEMPVNDVFMVPQYPVEKAYVGSVSMDRDLVSRSEGDMTLLADPGVQTELYSEQDADDLPSPLRRPLNFGEGDSSNVEDAHSEFSTSLQSLEANKPAEALPTPPPSEKPGKYVRRRPSPSTKVPLRRPKCAPPTLQGQPTLPEILNEELDKTSDFPSSSISQAMKEHDRETELQLARTCYPGEHIEHEFNPEVCRSVGRPGTTAKMMNGLSQIQARLIQISKDDGTISASSVVFLMNYLEAKIVFKAYAPSSDPLNKPIGIAQLESGHIIVADTFNNRMMLFDEAGKVLGPFYSSSSLYHPSAVVELEHGGFAVKDNNSISVFSSEFECCKVIAKGKLSRPYGLTVNAEGLLVTVETSLTGNLTIVTLNPGSGNVESRVKVDLGLSSHAKSESKPRFIAWQGECRLLVVDLGLNCVYIIDAFKGVVLKRFGEYGQGRDQMHDPSGIVCDGDGFILLGDSRNHRILIYDPDGRYISVLEVDVPVRRPSGLYLTSSGNLLILNYWENSVAAYRFQEIGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRF3</accession>
    <name>A0A3R7PRF3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TMEM131 second Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001135">
        <property type="protein sequence ID" value="ROT80285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRF3"/>
    <dbReference type="STRING" id="6689.A0A3R7PRF3"/>
    <dbReference type="OrthoDB" id="168404at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039877">
        <property type="entry name" value="TMEM131-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056311">
        <property type="entry name" value="TMEM131_Ig_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22050">
        <property type="entry name" value="RW1 PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22050:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 131 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24495">
        <property type="entry name" value="Ig_TMEM131_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TMEM131 second Ig-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21766" checksum="32DD6FF215E0E713" modified="2019-04-10" version="1">MPLNSSYSPLIQLHNPHPHALQITEMYSTGGDLHLELLSGSQEGQKNVWNIPPYHTRPLMKANFVARRENNHTAYVRIVTSETDSDYLVVPVEVEVSSQPGLFCPQDGLHFGLRTPHDPPATLPLHLLNSAHKHIHIQNVITTPVNDAISIDFKPMKIPPGTVRPTQVATVTFDRDLDRVGYGVLVCAAPSQSEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUP3</accession>
    <name>A0A3R7PUP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane and coiled-coil domains protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_023693</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEX28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000733">
        <property type="protein sequence ID" value="ROT83123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUP3"/>
    <dbReference type="STRING" id="6689.A0A3R7PUP3"/>
    <dbReference type="OrthoDB" id="1323at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019394">
        <property type="entry name" value="TEX28/TMCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17613">
        <property type="entry name" value="CEREBRAL PROTEIN-11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17613:SF14">
        <property type="entry name" value="DEMENTIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10267">
        <property type="entry name" value="Tmemb_cc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="269"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="610"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="389"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="610"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT83123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="686" mass="74565" checksum="9E059FC33EE1B1B5" modified="2019-04-10" version="1" fragment="single">KKGNSNEVGGGGRGGGSSRRRSPLSVRKSAAGALEVNSTPSAANNVSGVAGGHGQATPQQARATRLPNTHSQQDDGAAHSSNEDCDAETVPSSGVSNGSGELVETLRGGDVEDDEHSPHIQRTREALEHIQAKIQKTRDLIKEEQKARDENVNEYLKLAANADRQQLARIKAVFEKKNQKSATLIQQLQKKLENYQKRLREIETHGLVVAHRQPKEVLRDMGQGLKSVGGNIRDGITGFSGTVINKPKEIAHLIKNKFGSADNIKELAGEDDRDEDRAHHGSATLPAGASLIPPTSSNHGVDLHHHHNISANLSSHHQSSSAQGAGGSSSGGHQGSKIGSEEGSECNSSITSESVPGGSTTLGHLTSPRNHHSQLTGIDFYTMPGGTSLEPLLLELRESREESARLREEIETIKQALAAEVNSMREGLAEERFRCDRLEEQVNDLTELHQNEMGNLVTNMADMEEKVQYQSEERIRDLHEIVENCHTRISRMEHQQAQQQQQYLTLEGLENSNARAVFVKLINVLLTVLQVLLLVVATVASILTPLMQTQTRIVVTTTFQSPPLSPIPLHPPLLPLLLSLVSNPPSSSPQSRIPFHPLFLLFPIPNRQSPLSSSSSPQSLVFPPSPPHPIPSSPPSPTPPPLPNLQSPPADLTLSGLIDITRKLHLAWVVLHLYCHVVRCRVFALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVK7</accession>
    <name>A0A3R7PVK7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001398">
        <property type="protein sequence ID" value="ROT78341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVK7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="48616" checksum="A595E00A6FD7FC54" modified="2019-04-10" version="1">MQFPPLHIHSPAPRPSSGVPSSANYPSKEMKGAKQQAKMKRGLFGKLFHLFYHHPLFLPPPSPSIPPPSTSPSTSLPLIHLSLPPFYSIHLSLPPRIHPPPLLPPSTTIPHSLPPPFSSPFYHNPPLLSHSIHLSLPPFHLPSSPFHHHPPLPSTSISSPFHPNPPLLSISIHLFLPPPSTSPFHPSTTISSPFNPQPPSTLPSPLPLLSPSTPPSTSLTIPPPFPLPSPFHLPSLPSTLPHPSSPFHPSTSLPLLPPFLPPFHPSTSLPLPSTSFLSLPPSTSIHLSLPPFHLHPLPFHPSPTNPHPSTLPLPSSPFHPSPPFLSLPPFLSFHPSTFLSLPPFHHHPLPSTPSPFSTFHPPSTLPPHPPSTPCSFPSTSIHLSLPLLPPFHHHPPLPSTSMFLSLPPPSTSPSSPFHHPPKQPPTETIKRNRAPEGEIRNPKSLRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q013</accession>
    <name>A0A3R7Q013_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein-like 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003154">
        <property type="protein sequence ID" value="ROT65025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q013"/>
    <dbReference type="STRING" id="6689.A0A3R7Q013"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000033">
        <property type="entry name" value="dnaJ homolog subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000026">
        <property type="entry name" value="Uncharacterized protein, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="354" mass="39654" checksum="7E5EA30BF2415638" modified="2019-04-10" version="1">MGKDYYKILGLSKGASEEDIKKAYRKMALKYHPDKNKSADAEEKFKLVAEAYEVLSDKKKRDIYDQYGEEGLKGGVPGSGSTDGTHYTYTFSGDPRATFQQFFGTNNPFSHFFNMDVDGHGTHDVFEDMDAEDDPFINMLGGGGPRMGGGTRRAFSFNPHDSPRFYESKGRHQDPAVTRDLYVSLEEVVKGVTKKMKITRNVLTADGRSTRREEKILTIEVKPGWKEGTKITFEKEGDQSPGKIPADIIFVIRDKPHPLFKRDGANLVYTAKLPLRDALCGTRVSVPTLTGQQVTLNFSNEVVKPQTTKRLQGYGLPYPKDPTRKGDIIVHFDIQFPANLTESAKEILSEVLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1R0</accession>
    <name>A0A3R7Q1R0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phospholipase D</fullName>
            <ecNumber evidence="3">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015760</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phospholipase D family. C2-PLD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002971">
        <property type="protein sequence ID" value="ROT66238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1R0"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1R0"/>
    <dbReference type="OrthoDB" id="6330677at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024632">
        <property type="entry name" value="PLipase_D_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF60">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12357">
        <property type="entry name" value="PLD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="10">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="297"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="611"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="764" mass="86070" checksum="A17C8C351D74BC20" modified="2019-04-10" version="1">MAMLRGYLYIDLIAADGLPDCDTAFFNIDPKDTSDPFAQVKVGNCVLCKTAVINNDLSPKWQESFRIPVCHVADEIQIQVLDKDHFDAGLLGEVSLRGGDLMDGETMEGWYPLSGCDGRINLKINYVPKDMMDMTFEVPDCYFPLREGCKVTVYQDAHCPPLPLFESVPTASGEPYDPPCAWTDLYKALNNAQRLIYITGWSVYAETVLVRGECDCEEAVGETVGDLLKRKAEEGVRVLVMVWNEKMSTGVTAGFMGTHDEETRLYFEGSDVEVAVVPRIRTLEGMASFFQDQFAQTCYTHHQKTVILDVPPEEGEDLPRLQAFIGGLDITDGRYDTPEHELFKTLTTVHVGDFYNGCATTTSEVGPRQPWHDIHCRLDGPIVLDVLANFTERWRNQVKDRESRLLPISDEEFALDAPAVCEEEFAWNSQLFRSITSDSALFDFNRIAAIPKRKGKYVDDSIHRAYIHQIRRTDSYLFIENQYFLGSAYGWDDEQSTKAHHLIPQEIAQRIVEKINAGEYIGVYVVIPMYPEGDPASKPVQEILHWQHRTMEMMYKLIAQAIEANELDTHPRDYLSFFCLGKGECPEEIPEDLPPPDPESPACLLREKARFMIYVHSKMMIVDDDYIIIGSANINQRSMGGTRDSEIAVGCFQPLQTREMSGEARGDVHHFRMALWAEHLGSVEDVHLDPGSLDCMRAVNEMADSNWSAYVADEPCKIEGHLMRYPVEVGQDGSVTALEGSENFPDTEAPVLGAPNFLPNKLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q487</accession>
    <name>A0A3R7Q487_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000206">
        <property type="protein sequence ID" value="ROT85710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q487"/>
    <dbReference type="STRING" id="6689.A0A3R7Q487"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="58339" checksum="BA9EF03183B09380" modified="2019-04-10" version="1">MRGRPGEVLSFQCPTFSPPPSPLNFNSLYRARFPFLSSPLLLSPPFSFALSSPLPSPFLFFFLPPLSFLSFLPSFISLSLFSLSLPSLFLTPSSLFSLSLSRPHSHFSLTSLSLTFPLTVLSLYPQPLTPSPPYFFILSPFLFTSLHLNHSDLSASKLLPLLFSHHPPSPSLFLTSPLTPSPPSVSPNLPYSPSHYHPPPYLPSTSALSLSPLPINLLSPFLPTVPFKAFSSRSPPSPLSPLSSPPLSLASFCGLTIPFQTPHNPNLSHSFPLTLSPSLPPLALSHLVSFCPLSPLSLLSLLLLLSRSPSLSSLPLPSLPSFPSPLSPFLLPSPSPSLPLSPSPLFSSLISLSPLFNNPLSLSLPLSLTPSRLTTPSLLLSHYSPCSTIPFPSPSSLFGPSRTLSLSPLPGSPSLSRSLASPPFPSPHPLLLSFFSSSASQLSLSPRPSSSLSPFPHPLRLSRSQLPFLHPRYSIPLPLAALSLVLSSPHLASLSFSLLSPSFFLHSLPFLSHSHIYSLYLSTLPPHTLPTTPAKRAINRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9M3</accession>
    <name>A0A3R7Q9M3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021392</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004485">
        <property type="protein sequence ID" value="ROT60917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9M3"/>
    <dbReference type="STRING" id="6689.A0A3R7Q9M3"/>
    <dbReference type="OrthoDB" id="6367965at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07066">
        <property type="entry name" value="CRD_FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050685">
        <property type="entry name" value="LDLR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270:SF62">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01392">
        <property type="entry name" value="Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00063">
        <property type="entry name" value="FRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63501">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="FZ" evidence="10">
        <location>
            <begin position="152"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT60917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="540" mass="57269" checksum="708986906A77B379" modified="2019-04-10" version="1">MTHHTHAEGDMTHDHTHAEGDMTHDHTHSDGDMTHHTHAEGDMTHDHIHADGDMTHDQTEPNSEIGHGHVHAEMGHDMTAAHEIAEDAPTAAAAAPTERTIVSVSSTGPGAKVEVKSSESEVSAAPSSSLPPLLDVLGPHATPAAPPQAGSCRPQPGDVRRPPYALTALPNWANDRTDHELHNASLPFFRDVIVRSSCSPRAREYSCAILEPPCGASGAILPPCRTFCRSVASTCQEFVIKGFGLSDVFNCDKFPDSTDPAVCFDATQEPCLGLEHRCGDGRCVAKRLVCDGISDCVDQSDEATCPGRLPAPVGDAATAASGNTFQQLPTPSELPDARTGGRELPLEDYSTLDRPEAALEGQAPPADDYPVYDDYSVTEDYPEGPQDYVTDSFDYTEVVDSSVATLPPVDELEGPVDAANESLAGAEDPFQRDLVDFSTEFAPVEAFMPTEEPVASEAQDFVAEGDFLSTDGPVLICDHEKFLCQNGFDCVDLAAVCDGLPHCSDGSDEANCTSIGESPKFITSSSPSAGLGLHSAFAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCV8</accession>
    <name>A0A3R7QCV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001852">
        <property type="protein sequence ID" value="ROT74734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCV8"/>
    <dbReference type="OrthoDB" id="6605262at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="817"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="966"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="880"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="913"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="976"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1090" mass="120042" checksum="B53DD28CE7B98211" modified="2019-04-10" version="1">MLPLKTRALTSHAASLCPHESNAPPSPQDGHVVTETERTTQHEEYDNESLPDSGSSLSDGSVHEEARETQHNIVHTKDEDLVEYYAVPRGGTLAQGVKLGEGMHVVSEDFHEDREGEDLDSLSERLRRARRLGALKPKPRDTPERTDALTRRPLDYHQEEETRKSETNRWLENHFGSESGRSGSSHHDLEDDSAVHTAGGNVITITMSPRPATPEDVTDAAPAKEITDSMIAAARARLRSTGRILDDSDQGTPPTSPPAKVHSSRATFTPPPPVSSPGVNGRSSDDPVYGSRFRSGSPGGFMQSRIFSTPSRNSRQSPPDSPPPPLPSTPPPQVTNVGRSQSFNVTTKSWLDNSTVSHSSRPLESRMKEYRSEEQLDAVGHKSGKRWPPPRDPSPEPRRETTPPPPPRHRVSSASQTNNAHYNTAPARSSRSSRKKEISSQTEARDSATQTGPSPVPPPRTKRKNKPRTYYFGQDSSSSTSESNRGRTPVNSTSTTTMSYTRTTKDNRSSPKVERRFRTEKTITPVVVVPAPGINNHNSSVERTSSQKSLQNRSWHYRSMDELSSGMENSTPRSSWTNTVDPRRRPRNYGDQTKEPETRTLPKKLVNGTSSPSKTYIFGGDNTSSRSRLSSGTSSNLRRAHGGSMVNVSLAGMSSPKSPVQPEPQETFSSSRNSRHVSRSHSLNVKPAGLSVAPSINVAPSFPSTTLSSQQRTSSMYKSTPYLRSPNLIATIARSNSTRRTDEDHHSGEYERATSPPSSERRQWSNGSRYIPENNRNSNRNDTVTQNGSINNRDDEKRDRFMKGLLTSAPELYHFIHGEDNGKQSSDNANRTRNSPNPPESPPQLIRPPGSPLTSPSATSPPASSAPRIFTFGRGENGSLKRTPSLSQDNNNRFSSLGRHRESLNDNNHSNYRDQYTNGNNNNNTNQRNSLSSQYHRNAMLNNANDGTSSLNRPRFNLKAAGGSLLYSPSFRGRNDQSSSAPNSWTRRGSDEYQSPSQRWRDQEDTIGGKSGGKVTSNITRDGAVLIPRVENDGTLLENLTLRSGALLTSRPGGWGEPQQCPPNRAGSGLSLRVRQETREATIDLQECVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QDS0</accession>
    <name>A0A3R7QDS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative proline-rich protein 5-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QDS0"/>
    <dbReference type="OrthoDB" id="6370177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="43390" checksum="C52014AD753D8A24" modified="2019-04-10" version="1">MMAFCLRPRLHSDEESEESSPPSASFISSPGDSDVFLKESAFGSFNSDASSLIWPQVSPRRLRFRSSSSSRSSQVSSSSESDKPSRQGSVKRIVRSLSAILRPSSEGDDLELVLQPTASLLHDVGEALLHVYRSNTFPSEGLCAFHQKLTVLVMSGGGASLTGTWRHQVVPTGTRLVAVRVASPRDGDRVAALLTAWSCLYATTLPLLQALLAPVTSLDVRRDVLQAFRDSVLPYAGLPSALASVHSTSPSTRWRLKQMLLLLARLEPCECRLSFENCEGETKETQESSQERGDVEEEEMRGEESSSVTKLSHTTEALGLLLQAEMESTHLARPVLQRLLHLHHGGESDFWASHELQQRPSSGVRLEVPASPRPLLVRNLSSVDTLEDLLRSAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QIZ4</accession>
    <name>A0A3R7QIZ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Core Histone H2A/H2B/H3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_012823</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT68968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QIZ4"/>
    <dbReference type="STRING" id="6689.A0A3R7QIZ4"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000024">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="80"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT68968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="19377" checksum="D90895C947AB805D" modified="2019-04-10" version="1">MGGANAHCASHTLLRTAKPALPARLFPICTDTNNHRNGSYQADCPQVYRRQGPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMM0</accession>
    <name>A0A3R7QMM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022868</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000617">
        <property type="protein sequence ID" value="ROT83958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMM0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="660" mass="73036" checksum="A0404917E0D977BA" modified="2019-04-10" version="1">MFGTVFGTNFRQLHFPRRHSSTRFHLFPPLPLPLLSTFDSGTPPLASTYPPSSSPLYPLSTPALLHSLPPILPLLPSLIHFRRRHSTRVPPIHFSIHFRRRHSSTRFHLSPLSSPSAPLSIHFRLRHSTRFHLSSPPPSSPSPLYPLFRRRHSPLASTYPPFPPPSVPLSIHFRRRHSSTPFYLSPSLSNPLSIHFRRCHSSHSLPPIPPLLPLSPPPLYPVSTPALLHSLPPIPLLLPSTLPSLSTSTPSLLHSFTYPPSPSLYPPLSIHFRRRHSTRFHLSPLPPPPPLPPSLSTFDPSLLHSPPPILPPPPPLPSPLYPLSTPALHSLPPILPSPPSTPLSIHFRTPHSSTRFHLSSLPSLYPLSIHFRLRHSTRFHLFPLLLPFYPPLSIHFRLRHSSTRFHLFPLPPPLPPSLSTFGSGTPTCLHLFPSPPSLPPSLSTFDAVILHSPPPIPPLLLPLCPPLYHFRRPSLHSLPPILPPPPLSTFDSVTPPLASTYPPPSSSPLPPSIHFRRRHSTRFHLSSLPPSVPLSITFDAVTPPLASTYPPSPLLPPSPPPLPPSLSTFDSVHSSTRFHLSSLPPSLSTFDAVTPPLASTYPPPSSPSLPSLLFHFRLRHSTRLHLSPLPSPPLPSPLFHTPCFPTLTTNNNSPAVKLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNA9</accession>
    <name>A0A3R7QNA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acid sphingomyelinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_022292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a sphingomyelin + H2O = phosphocholine + an N-acylsphing-4-enine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17636"/>
            <dbReference type="ChEBI" id="CHEBI:52639"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="3.1.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19254"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000531">
        <property type="protein sequence ID" value="ROT84532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNA9"/>
    <dbReference type="STRING" id="6689.A0A3R7QNA9"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061750">
        <property type="term" value="F:acid sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006685">
        <property type="term" value="P:sphingomyelin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF34">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018572583" evidence="6">
        <location>
            <begin position="19"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="7">
        <location>
            <begin position="48"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT84532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="350" mass="37748" checksum="0465D9539EF6847B" modified="2019-04-10" version="1" fragment="single">MAFRQLWIILFVVGSLSAAPWDGRPGQPTSSPAHFLLHALVPEHNQVRDLTCLECRTAAGVIAAMMAEGATVEEIEDQVILDCVLLDLFPPDVCSGMVRLSGAEVLHVLNATKYDHETVCGWLLGGHCQHTQLDPWTLAVPGGKPAPSHPEPAQPTEGVVRILQLSDLHVDLLYDEGSAAHCEHPNCCRHAFGDPAPGELAAGHWGALANCDIPLHTLDDLLAHAALTNPDLVYVTGDLPPHDVWAQSHASNLLAINTTVQLIAKHFPDVPVLHALGNHASAPVNSFVVPTAYADGWSMTWLYDSLAAMWAPWLPEEALPDVRKGGYFSCSPKPGLRVISANMNYCNTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QR64</accession>
    <name>A0A3R7QR64_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001805">
        <property type="protein sequence ID" value="ROT75173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QR64"/>
    <dbReference type="STRING" id="6689.A0A3R7QR64"/>
    <dbReference type="OrthoDB" id="10682978at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="647"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="887"/>
            <end position="899"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="908" mass="99474" checksum="B2639AFF37B4476C" modified="2019-04-10" version="1">MRGIIHIYPDLLPGVFAHRRGVPGEPQSQVGRREPREPSRESQGAKSGEPENQVGGREPREPSRESQGAKSGKSHRRPSRESQRESNRGEPSRESQRTKSGEPENQVGRAREPSREKRTKGAKGEKNQVGKSEPGSKSERETKSGEGAQVGESQGAKSGELGRAREPSRESQRKPSRKNENQGKPKVGRAKRTKSGEPENQVGRARAREPSREKPGSQVQVGRAKGARKSGEPGSQVGRAREPSRESQGAKSGEPGVGRPGSQVGAREPSRRTKGGQVGRAREPVGKEEPGAKRREPESESQPSRRAREQRARDQVGRAREPSREEENQVGEPSRESQRTKSEEENQGSQVGRAREPSRESQGAKSGEPENQVGRREPREPSRESQRPSRERPGEPSRESQGRESQGAKSGEPENQSGESQGAKSGEPVGEPEEPSRRERAREPSRESQGAKVGRARETSPEEETKGAKSGRAREPKVGKKKRTKGAKSGEPENQVGRAQGSQVGRAREPSRESQRTKVGQVGRAKGEEAKSEEENQGSQSGEPENQVGRGRRESQSSRKPRRAKSSESQGSQVGRAKGAQVRESQRTKSEEENPRSSQVGRSQRTREPSSGEPGSQVGESQKEPSREEPSQVGEPGSQVGEPEPENASKTEPRRREPREPKSEEENQGSQVGRAPGNLVGKSKGSQSGRAQKPSRRKRTKEAKVGRGTKSGEPENQNREEPGSQVERAKSGEPENQVGRARRTKSQRSQGSTKSGEPEVGRRPKSGGEPAKSGQPGSQVREKPENQVGRREPKGAKSGEAREPKSEEENQREPGSRESAEEPRNQSRESPSRESQVGRTQPSPGEQRTKSGEPENQVGKSQRARETAENQVGRRTKSGRATEHQARSMRRRPRRKKSTPPHALTFMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QUN6</accession>
    <name>A0A3R7QUN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAC-alpha domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_002359</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001314">
        <property type="protein sequence ID" value="ROT78926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QUN6"/>
    <dbReference type="OrthoDB" id="10057776at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03590">
        <property type="entry name" value="CLECT_DC-SIGN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033989">
        <property type="entry name" value="CD209-like_CTLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018608077" evidence="4">
        <location>
            <begin position="16"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="5">
        <location>
            <begin position="342"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="48673" checksum="C1D0E6E652E43587" modified="2019-04-10" version="1">MSLLLILALSAFASSASVRSISDVTEQQRCDVTVGVTYPETAEEEPLVTCSSQCLSDDEQTWFMGSMYKHLAGLTALGLMVEVKYDKAAVIDCRLVPIQSTSSLLEAFQLCDNTVVATTARTFIPTGTNTGTFIPTGTNTGTFIPTGTNTGTVIPTGTNTGTFIPTGTNTGTFIPTGTNTGTFIPTGINTGTVIPTGINTGTFIPTGTNTGTIIPTGTNTGTFIPTGTNTGTFIPTGTNVGTSVPTGTNTGTFIPTGTNTGTFIPTGTSTGAVIPTETIVPTGTNIATSGPTEVTTVGTTTKDVIACEHKETSPSTPAPPTTTTIQLPTTTAHVCPEGWLLNAGSCYHLSASKGAWEEGRTYCSDNGGAYVKISSEEEWDFVKSMLSETTWIGLHDRDTEGSFVWDVDGSTPVYTKWHSDEPNDANGGEDCGEMNERMGFMWNDQPCRDARPFVCEMSANVLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLH7</accession>
    <name>A0A3R7SLH7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016134</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003018">
        <property type="protein sequence ID" value="ROT65899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLH7"/>
    <dbReference type="OrthoDB" id="414826at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01010">
        <property type="entry name" value="CRISP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="596"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="408"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="948" mass="106493" checksum="97E015DBD9CF7653" modified="2019-04-10" version="1">MDPQFSPAKTRWALQPPYTVASRETYKVVKSAVIIASSPVLIAVPPRSPLSCPNPSLPQPSPPPLPIPYFSPPHPYDLPLPIPYPLPLPPSLPLLPRRYRLFPLPPPPLMYSAAHTSDSGKAPCSGLCLFSISSCVVTRRHAPFTWFLLSGHAYHSHFIAPPGYGVVIEVADLRLRRSRRCAASRVLVQAGLSAQQSRIRPLVRFCGRGPKNPLWKTTFSEVNIEYKSNGATRKKSEVKSKSASKSRSQKLVTYEDRPSANSAARGRPSSPSSSSSSHLTRAEKIARIKALQRLYNLRSSDRKASPSAGYQPASQRRRQYYSYQQNTNSRRFYRHSNGTGDGGAYDPTNDTIVIDGDDFVYDADSHAFGAITGTSAEAPSVRLFSVGEPTWISSDFILHDGMNATEAEVDEEAGMVASPRKANKRKNKKNKKKRKKQGKKQRAKEDPLEDEDGSLERIPRSAWAPSSGSYRGSSRRSYHRTRYYTVSRGRPSRRKQYRVTISRHDPPARTSSPAKPQRDPATSSSPSRGHNEIIPRKPSKHVPESSKEVYYPSKTFGFLDPKPAKPEAEEAPATPSSGHERRELFVLKVRSFKSHCGGEITDDRGRFTSPGYPQKTGGKNSCFWRFKTPPGSHWKLQCTHFRIRKSRNCMRDHLAIRINEGDWTRYCGREGPSVALTSSHAAYVDVVLNTFRNDSARTICSWESRYLGTSCSSWSCTDYRKLTSDHTMCRSTPPTCSVYLEGVTRSERAFILDSHNKYRAIVARGEENEGLPGPQYSASDMQQLVWNDELAQVAQAWASACPDYHDCQDCRRVLSRDYYVGQNIFYEWSSSNGGSVWETAVRLWYEEVKYVPNYLTKSFRMMDHAVIGHYTQLVWAETREVGCGATYHDCSKVFKGRMWKLKCKIYVCNYGPTGNYVRKPMYSIGPPASACPPDTRPSIQYPGLCALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMM4</accession>
    <name>A0A3R7SMM4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LIM domain protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_014439</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002807">
        <property type="protein sequence ID" value="ROT67501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMM4"/>
    <dbReference type="STRING" id="6689.A0A3R7SMM4"/>
    <dbReference type="OrthoDB" id="6352355at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09388">
        <property type="entry name" value="LIM1_LMO1_LMO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09390">
        <property type="entry name" value="LIM2_dLMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000015">
        <property type="entry name" value="LIM domain only 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000016">
        <property type="entry name" value="LIM domain only 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050945">
        <property type="entry name" value="LMO_RBTN_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45787">
        <property type="entry name" value="LD11652P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45787:SF1">
        <property type="entry name" value="LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="80"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="27506" checksum="84906E5738F2A6E5" modified="2019-04-10" version="1">MTMKPAAETERNTSPQDCAGCGKRINDRYLLKALEMYWHEDCLKCGCCDCRLGEVGSTLFTKGNLILCRRDYLRLFGTTGYCSACSKVIPAFEMVMRARNNVYHLECFACQQCNHRFCVGDKFYLCDNKILCEYDYEERLVFASMACTPSSLAQLKRQIGGLESPAALDDSRKPPPSTTSTSTPLQHGPLHHHHHNATPTQPQQPPPPAPQQLPSQQQQSPLVQQQQQQQQQAPPAPPPQRPMVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQU5</accession>
    <name>A0A3R7SQU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002340">
        <property type="protein sequence ID" value="ROT71132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQU5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="438" mass="47166" checksum="E74F78C804936461" modified="2019-04-10" version="1">MSQGRSAACESGSPRLLRSRRELKKIHPTPVTRTPFPPSLLLPFSSPSPLCPRLFDFPPRFLSSSPVPRPPAAPSLRPSYSIPCCSLSLLPVLCCSLSPFTSFFLASFYFSPSPSCFLCPLCPFSLLSPLAFTLPLFFHTYSSFLLLSTSLPSSSLFISPISSLLPSLVPHSFSFYLSTPLLPSLAVLRPSLPLPPSIHPRLTLALLPPPPPSLLPHTSFLVSPPLVRPSIFPSSLPLPPSPQPHLPLLPIPLPPYPPPSPQPTSLSPFSLPTHLPSSPSFFPRILLPRPNPPPSPPHPSPPRTSLSPLPLPPRPQPTSLPPILLPPTSLSLSSFFPRILAPSPTHLPLLPILLPRILPPRPYPPPSLPILLPPPRSLAPTPPPSPPHPLPPYPPSFAPSYPPPSPLPTLLSSILPPPSQQILFPTPRPDSSPPNGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ST10</accession>
    <name>A0A3R7ST10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prm7p</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002000">
        <property type="protein sequence ID" value="ROT73721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ST10"/>
    <dbReference type="STRING" id="6689.A0A3R7ST10"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="40412" checksum="DCAC2754DEC9C4CD" modified="2019-04-10" version="1">MTAMDPTIAMDPTIPMDLMIAMYPRTAMDPKTAMDPMTAMDPKTAMDPMTAMDPKTAMDPTIAMDLTTAMDPKTAMDPTIAMDLRTAMDPKTAMDPTIAMGPTTAMDPTIAMDPTTAMDATTAMDPTIAMDPTIAMGRVSFFAKLFQKMWETDAPPPPILLLSASGENYAAREPDRRKREESLIVLDRRKRRSVSTIPSSAPPHPLPFFLPPMPRSPLPFPSPLPSLPLPPLPSYPPFFLPSSDPPPPPFFLPFFFPPLPLPPPLLAPLPPFCLLLPFSAPPPLPFLPLLCPLPPPLLPPLLLPSPSSSPLCPPPPPLLPPSFLSPPSPLSLPPSSLLSPPLPFSSPSSAPPPPPLLPGRPLILRRAREGRGHID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STF5</accession>
    <name>A0A3R7STF5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cyclosome subunit 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_007250</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins. May recruit the E2 ubiquitin-conjugating enzymes to the complex.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">The mammalian APC/C is composed at least of 14 distinct subunits ANAPC1, ANAPC2, CDC27/APC3, ANAPC4, ANAPC5, CDC16/APC6, ANAPC7, CDC23/APC8, ANAPC10, ANAPC11, CDC26/APC12, ANAPC13, ANAPC15 and ANAPC16 that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa; APC/C interacts with FZR1 and FBXO5. Interacts with the cullin domain of ANAPC2. Interacts with UBE2D2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RING-box family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001918">
        <property type="protein sequence ID" value="ROT74258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STF5"/>
    <dbReference type="STRING" id="6689.A0A3R7STF5"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16456">
        <property type="entry name" value="RING-H2_APC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000111">
        <property type="entry name" value="Anaphase-promoting complex subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024991">
        <property type="entry name" value="RING-H2_APC11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12861">
        <property type="entry name" value="zf-ANAPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="53"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00054113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00062360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00078349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT74258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="103" mass="12254" checksum="C8AF3AE513C450FC" modified="2019-04-10" version="1">MIVLKRSWRKYSIDNLEQVMKVKIKSWTGVATWRWVANDDSCGICRMPFDGCCSDCRLPGDDCPLVWGQCSHCFHIHCIMKWLQSQQLHQQCPMCRQEWKFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYH3</accession>
    <name>A0A3R7SYH3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative sialic acid synthase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000983">
        <property type="protein sequence ID" value="ROT81397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYH3"/>
    <dbReference type="STRING" id="6689.A0A3R7SYH3"/>
    <dbReference type="OrthoDB" id="9928645at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047444">
        <property type="term" value="F:N-acylneuraminate-9-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051690">
        <property type="entry name" value="PseI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="PseI/NeuA/B-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42966">
        <property type="entry name" value="N-ACETYLNEURAMINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42966:SF1">
        <property type="entry name" value="SIALIC ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseI/NeuA/B-like" evidence="1">
        <location>
            <begin position="38"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="295" mass="32351" checksum="AE1F6A906FD9F795" modified="2019-04-10" version="1">MEPLELVPGRYIGEGQPCFIIAEIGQNHQGDVDLAKSLILRAKECGADCVKFQKSSLKDKFNRHALARPYTGPNAWADTYGAHKEHLEFSREEFQELQNYAREVGIPLTASAMDIPTVELLDELGVPFIKVGSGDVHNLPLLRRAAATGRPLVVSSGMSDIEWVSRVYEELSAAQDPPTPLVILQCTSAYPTPPEHVHLRVLDTYAQVFPHAHIGYSGHELGIHVTVAAVARGARVVERHITLNKSWKGSDHACSLEPHELRELVEAVRSVEAALGSPLKAFQPSEEPCFSKVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T188</accession>
    <name>A0A3R7T188_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000365">
        <property type="protein sequence ID" value="ROT85228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2463" mass="276737" checksum="1CEA16B4A2C40EEF" modified="2019-04-10" version="1" fragment="single">VQTNQLLSFVVQTPTTLSFNTNQLLSFTPNQLLSFTTNQLLPFTPNDQNSVQVMTHGTTLCRSTNQLLPFTPTNSCVHKPTNSCRSHQPSSCVQHPTNSCVEPVSHQRLLPFHTTNSCRSHQKRLTLAFELCLESLSRQRTLVVHTTNSCRSHQPNSCRSHQRTLAVSHQRNSCRSHQRTLVVTPTNSCRSHQRTLAVHTNELLSFTPTKNSCRSPKNLAFHTTNSCRSTNELLSRSTLDVHQPTSCRSHQRNSCRSQPTNSCRSHHELFAFTNQTTLVRSPRNQLLPFTPTNSCRSHQPTLVGSPPTTLAVHEQPTLVVHTNNELLPFTPTNSCRSQTNQLLSFHTTNSCVHTNELLSFTPTNSCVHQRTLAFTPTNSCRSTNDSCRSTNELLSFTTNELCRSHKNSCFHTNELLPFTPTNSCRSHQPNLAFTPTNSCRSHHELLSFTLVVHQTNSCRSHNATLCRCTQRTLVVHSCRSSFTPTLLPFTLLSFTTNQLLRSHQRTLVVHTKPTLVVFLSFTPTNSCRSHNQLLSFTNQRTLAVHTNENSCVHTPTKPCRSHQRTLVVHTNQLLSFTPTTLVVNQPTLVVHTNTLAVQHNELLSFTQTNSCRSHQRNSCRSHTNATLVVHTNDSCRFTPTNSCRSHNELLLSHQRTLAVHTQRTLVVHHQPKLLSFTPTTLLSVHTNELFVVHTNNSCRSQTNELLSFTRKHELCRSHQPTLVRSQNQRTLVVHTTNSCRSQPTNSCRSTTTLAVHTELLPFNNNGTLVVQRNQLLSFTHNELLPFTPTNSLSFTPTNSCRSPPTNSCRSHQPTLVVQHQTTLVVHTNELLFVLSFTQPTVSTQPTLGHTKNSCHTNELLSFTPTNSCVHTTELLSFTTNNSCRSHQPLFRSHQPTSCRSHQPTLVVHTHTNSCVHTNETLSFTPTNSCRSHQRTLSFTQQLLPFTPRLLSFTPTNSCRSHQPTLVVHTTNSCSFTQQLLSFTPTNLVHVPNSCRSRPTNSCRSPPTTLVVHTNELLSFNQPTLVVNQPTLAFTQRTLVVHTNQLLSFTPTNSCRSHQRTLVRSHQKPHQQLLSFTPTNSCRSHQLLSFTLLSFTPTNSCVVSHQRTLVFTQPTLVVHTNELCRSPPTNSCRSHQPTLVVHTNQLLSFTPTTLVVHTNELSCRSSNQLLRSHQRTLVVHTNQLLSFTPTTLVVHTNETLVVHTTTNSCSLTNSCRSHQPTLVVHTNQLTLLSFTPTNSCRSHQRTLAVHTNQLLPFTPANSCRSHQPTLAVHTNQLLSFTPTTLVVHTTNFVVHTNQLLSFTPTTLVVQTNSCRFTNELLSFTPTNSCRSHQQLLSFTQPTLAVHTNELLSFTPTNSCRSHQPTLVVHHHTNELLSFTPTNSCRSQNQLLSFTPTNFFTPTNSCRSTPTNSCRSHQRTLAFHTNELLSFTPTNSCRSHQRTLAFTPKRTLVVHTNQLLSFTQHQRTLVVHTNNLVVHTNELLSFTQQLHQRTLAVHTNETLVFNQRLFVHTNQLLSFTPTNSCFSHNNSCRSHNQLLSFTPTNSCFHTTTPCLHTNELLSFTTNELLPFHTNELLSFTTNRHSCFHNQRTLVVHYQPTLAVHTNELLSFQTTPTLGRSHQPTLVVHTTLLPFTLGRSHQRTLVVHTNQSHQRTLAFHTNETLVVTTTTLAYQPTNSCRSHSHNEPLAVHTPTNSCRSHQPTLVELTTKLLCSHQQLLSFHQPTSCLVHTPTNSCRSLLPLCRSHQPTNNSCRSHKLCRSHQNTLLSFLSTPPTLVRVHTTNSCRSHQPKLLSFTPTNSCRSPNETLVFTPKLFVVHTTNSCRNKPTLAVHTNQLLSFTPTNSCRTHHQLLPFTQPTLVVHTNQTLVVHTNQLLPSFTPTNSCRSPNQLLSFTPTQLLPFICVHTNHSCRSHAANSCVHTKLLNSCRSHQLQLLPSTPTNSFVHSLPFTPPTLAVTNNSCRSHQANSAVHTNERSHAPTLSFTQPTLAVTPTNSCVHTNQLLSFTPTNFAVHNQRTLAFTPTKLLPSHQRLLPSHDNQLLLFAVHTNNFLSVHTNQLFVVQQPTLAFHTANSCRSHNQLLPFITKTLCRYTTNQLCVVHTTNERLPFTPTNSCRSLPNTNSCRSHQPTLPFTTSRTLCRQPTNSCSFTPSELCSFTANQPTLAVHTNQLLPSQQQLLVVHTNQPCRSHQRLLPCTQQLLPFTQRTLPSTPTNSCRSHQRNNCRSHHELLPFHTRTLAVHTNHSAVHTNKLLFTDTLPTLAFTPTCRSHQIQLLPFTPATLAPFNTKPTSCRSQPPTLAVTPLNPVAVHTTNLAVKHQPTIAFTTNQLCRSHQRTLVVHHTTKTLAVHTSELLPFTPTNSCLSHQRTYNELFVQHQPTLAFHTNELWSFNHETLAFTTNELLSFTPTNSAVTPTTLAFHTKPTLAVTPANSCRSHNQLCRSTPNELFTQTRVFSSLSTVASFASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S8M0</accession>
    <name>A0A423S8M0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Crustacean hyperglycemic hormone 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_011787</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004682">
        <property type="protein sequence ID" value="ROT60584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S8M0"/>
    <dbReference type="OrthoDB" id="6365952at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2010.10">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018251">
        <property type="entry name" value="Crust_neurhormone_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031098">
        <property type="entry name" value="Crust_neurohorm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035957">
        <property type="entry name" value="Crust_neurohorm_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001166">
        <property type="entry name" value="Hyperglycemic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981:SF2">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01147">
        <property type="entry name" value="Crust_neurohorm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00550">
        <property type="entry name" value="HYPRGLYCEMIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81778">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01250">
        <property type="entry name" value="CHH_MIH_GIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="100"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR631098-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT60584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="167" mass="19100" checksum="491DF6EA5261B133" modified="2019-05-08" version="1">MQDADDRLYKATSTWLRRRADEEPRSRRFSPPDSSRRRGNDWGSTAVLVSLLLVFPASVLASWDGNEIPPSLPSSSESSPATSLAGAQTANKRSISFDSCTGVYDRELLVRLDRVCEDCYNLYRNTDVAVECRSNCFHNEVFLYCVDYMYRPRQRNQYRAALQRLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBT3</accession>
    <name>A0A423SBT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heparan sulfate 2-O-sulfotransferase pipe</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_020519</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBT3"/>
    <dbReference type="STRING" id="6689.A0A423SBT3"/>
    <dbReference type="OrthoDB" id="10019582at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007734">
        <property type="entry name" value="Heparan_SO4_2-O-STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129:SF15">
        <property type="entry name" value="URONYL 2-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT61671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="218" mass="24551" checksum="5626DD7DA1E41E32" modified="2019-05-08" version="1">MGRFLQELLTYPMPSLGTLGKVSPLSFVDQQQDFPGTLAPGIPGIVSVAKAQFWPSRSEGDAGDGRRETISSTRLSSHLGFVHISSLVYNQRLLNHGEQLELVENLTGALRAAPTHTLSYDRHLYYTNFTELGSVAPVYVNIVRDPVERFISSFYYRRSQERLNRIPAQGRTATPSPKWLNRTVEQCVLAGDHECAFQPGDEKEMMLTYFCGHHDFCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDV4</accession>
    <name>A0A423SDV4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_019780</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003703">
        <property type="protein sequence ID" value="ROT62388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDV4"/>
    <dbReference type="STRING" id="6689.A0A423SDV4"/>
    <dbReference type="OrthoDB" id="283091at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="13">
        <location>
            <begin position="2"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT62388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="103" mass="11386" checksum="8D13042E0E589F12" modified="2019-05-08" version="1">MGDIEKGKKIFVQRCAQCHGGGRRQAQDGPQPARPLRAPDGAGRRYVYTDANKSKGITWASDTLDIYLTNPKKYIPGTKMVFAGLKKKGERADLIAYLEDSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFW5</accession>
    <name>A0A423SFW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003497">
        <property type="protein sequence ID" value="ROT63075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFW5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="437" mass="47274" checksum="F2548C808FC2C3DC" modified="2019-05-08" version="1">MTSPQSLILLPRRPRSPTQAHSPPPHPRSRTQASFPSPAPTSPPPKPHSPPRHPRSPPKPHFPTSPTHSLPRFPPQASFPSPRSPPAMPPTFPTQASFPFLPRHPTFPTQVSSPPHHPRSPPKPHSPPPPPTSPPSLIPPHPSLVPPLPPHVPHPSLIPPPPHPTPTHVPTQASFPSPPPLPPSSPIPATHVPPPCQPTFPPPPTFPPRHHVPTQASFPPATTPPYLHCFTHYPPPISFGSLLSCSILLSTSSVPSHPSKPLPNLSLLSPSFTHPSFTYPSVTHFPSSYHTTQSLSLSSPSFTHPSFTYPICLPTSLHPPTTHSSAPLSATPTPPSLYPSAFSAILPYPLFTHLLLPITRLPPPPPAPTPLARDPTSIFHVFSRNQSRLGLAMRFSYFTCLARPRVRSDAHPFSGVVAKRCLLASRILFCGDQKLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SG85</accession>
    <name>A0A423SG85_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003474">
        <property type="protein sequence ID" value="ROT63212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SG85"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="446" mass="47910" checksum="12CBC1801E5513E2" modified="2019-05-08" version="1">MIRYKEKQSEGRIAATRGKSINTNHTSHASHLHHPAPAPHIPSTSSLPLPLTSHLHHPCPCPSHPIYIIPAPSQSHHIIPAPAPHIPSTSSLPLPLTSHLHHPCPCPSHPIYIIPAPALTSIYIIPAPAPHIHLHHPLPCPSHPIYIIPAPHPIYIIPAPSHPIYIIPAPAHLHHAPHIIHHPCPCPCPSHIPSTSLPLTSHLHHPCPSHPIYITLPLTSHLHHPCPCPHIPSTLPAPALTSHLHHPCPSHPIYIIPAPYPIYIILPLPLTPSTSSLPCPHITPSTSSLPCPSHPIYIIPAPAPTSHLHIPAPHPIYIIPAPHIPSTSSLPLTLTSHLHHPCPAIYITSHLSSLPCPHHSCPAAPAIYIIPAPPHLHHPAPAPPIYIIPAPAPHTPSTSSLPLPCPCIIPAPAPVCLAEYLAIILIAHLPVSSTCLYYSLLVSDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGV5</accession>
    <name>A0A423SGV5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative glutaryl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018689</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003441">
        <property type="protein sequence ID" value="ROT63432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGV5"/>
    <dbReference type="STRING" id="6689.A0A423SGV5"/>
    <dbReference type="OrthoDB" id="435240at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046949">
        <property type="term" value="P:fatty-acyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000003">
        <property type="entry name" value="glutaryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052033">
        <property type="entry name" value="Glutaryl-CoA_DH_mitochondrial"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42807:SF1">
        <property type="entry name" value="GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="60"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="175"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT63432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="261" mass="28936" checksum="735A4682EA1FB2DB" modified="2019-05-08" version="1">MAATRTLLRSLYLRSSPQLLSRAQSSVAAPQPHATTSEKSSAPKAKFDWRDALNLESQLTEDEIMIRDAFYAYCQEKLMPRIILANRNETFDREIMSEMGDMGVLGPTIHGYGCPGVSSVAYGLIAREVERVDSAYRSAMSVQSSLVMYPIWDFGTEEQRLKYLPKLARGEIVGCFGLTEPNHGSDPAGMETRAKYVPSDKVYILNGSKTWITNSPSLTSPWFGPSAKTVTFADSSWRREWPASPAPRSRGSSRSVPPTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLV1</accession>
    <name>A0A423SLV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative LON peptidase N-terminal domain and RING finger protein 3 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016902</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003133">
        <property type="protein sequence ID" value="ROT65151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLV1"/>
    <dbReference type="STRING" id="6689.A0A423SLV1"/>
    <dbReference type="OrthoDB" id="264917at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16514">
        <property type="entry name" value="RING-HC_LONFs_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF42">
        <property type="entry name" value="LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="243"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="7">
        <location>
            <begin position="333"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="161"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="550" mass="62799" checksum="423A591EDAE6D3B9" modified="2019-05-08" version="1">MHCRRPRRIPLLGPLRAFRFIWSRVAFPAPDGAAERKGDCESGFLLSLGFPPNDHLLLSNRSHVLHTLGRAEEALSDAEAAIRCRPEWAKGYFRRAMALISLGRFEDALVSLLQCAVLEEPDSLRSIKDEITKALHRLLVKLTNRRRVSLEGRGNCLNGYNRLSPALSDPSIPPESDSEDSEDSEDGRRKHPSGVAARPVEEEMQLRKLMDKYRHEIERSRKSSTGYVRHIDLSNVEKNDFECTLCYRFLYQPVTTPCGHSFCRTCLDRCLDHSTNCPLCKTSIKVCLSERSPTVTEFVHHAMEVVMPNECLDRRRQHDEELDELAAAGKDPHHEIPVFIATLAIPTITCPLHVFEPRYRLMIRRCMESGTREFGMCMPMETAENGYADYGTILEIRDVEYTPDGRAIVNTVGSRRFKIVSKSARDGYNTAAVEFLEDNVVPTAKLGESRQLHDTVHTLASRWFESIEPMTKRRILSHYGHMPSVEGEYWTLSNGPAWMWWIVAILPLDPRIQLSILRETSLVRRLEVLHRILRCVMAQQRSRQNGAVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN26</accession>
    <name>A0A423SN26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative ceramide synthase 6 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016382</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003063">
        <property type="protein sequence ID" value="ROT65645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN26"/>
    <dbReference type="STRING" id="6689.A0A423SN26"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="UniPathway" id="UPA00222"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="10">
        <location>
            <begin position="153"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="43758" checksum="EEFCAE9048A5878C" modified="2019-05-08" version="1">MREADGSMEFLFIPQIQQYLQDNVASDWWRRCSATFWSQEFWLPAGLTWDDIHTSLYDILFIPLLVGLFFVLLRHCVVEPFLLLPIARKAQIPNKRPRPPEPNKTLQVVFQRYETSPPKKVLAEASRATRLTERQVERWLRRSFAMNRLNRHDKFLDCGFKLVCHVWFGIMGAAVTLSKPWFWDTTLCWKGYPDHPVTTDVYWYYMILLGYYWAITYSELPRPGGKGSDKAQMILHHSLTILLIVFSWTTGYVRIGSLILFVHEYSDIALLAAKVCHYSGNDAPTEPLFVAFLVLWGITRCGILPFWIVRSVFTEATPAGVQMPALYMMQSWFVGLLCLTAIWTGLIVRTVSKKLRGEGLKDARSATEDSESDKAEKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNS3</accession>
    <name>A0A423SNS3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003028">
        <property type="protein sequence ID" value="ROT65843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNS3"/>
    <dbReference type="STRING" id="6689.A0A423SNS3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="45415" checksum="3C1BAAEF4E3EF79A" modified="2019-05-08" version="1">MTYVRPNSRADPVPFTRSPAQRVAYAVQSLVSGFPPSLPLPQPCAARAAAAAPLGSRPPPLAVPVWVVVPLPCGVWACRRTCHLHTKREGPAAFSACALPVCAPAQNWARLSFTGLGALFCVHVCPSSLGLSLPPVWRLPSLLRVRHVLARRLVLTVCPLSRPSLPCRLSRYSPPPPRPPFYFRFSRPPVLPHSAPAHPGPPHEARPSLCPPFVSPSSAPSPPPSLSSLPPSPPPPHRPPLLQLPRFPVAPFSLPSSPFPLLPLPSPLPLTGAPLPTPPSLVLLPHRPPSAVAFPDLLPVPPASPAHQTPFTQLPPVPVFLPHPPPPLPFRWTPVTLTPPRFLSSFLTPVRDPRSPPPPFCGPLDRPALLTPAASQSSFLIAPSLPSLVSSFLTPSFPLPPPAGSASPLPLPPPFALLRPALGNLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPA9</accession>
    <name>A0A423SPA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rap guanine nucleotide exchange factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002996">
        <property type="protein sequence ID" value="ROT66060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPA9"/>
    <dbReference type="STRING" id="6689.A0A423SPA9"/>
    <dbReference type="OrthoDB" id="21144at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF327">
        <property type="entry name" value="EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="240" mass="26058" checksum="678C799A83CED770" modified="2019-05-08" version="1">MVGGVGGREGLSKRAQLLRKFIKLAAYCKEEQNLNAFFAIVIGLSNVAVTRLTQTWERLSSKFRKMYTEFEMLIDPSRNHRAYRIYVAKLQPPILPFTPLLMKAASALPLATPRAQATVGGDAGDVLRTLWDSFEILGSSFALLECPLGAGDDGDALCPPWDVFEILGSSFALLECRLGAGDALRVDGTPFCIPGTLLNSPGMSFVMVGGFSRVCDVPLISSGRPSRYWKVLHGRATSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPN0</accession>
    <name>A0A423SPN0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aromatic-L-amino-acid decarboxylase</fullName>
            <ecNumber evidence="8">4.1.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DOPA decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015901</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.28" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPN0"/>
    <dbReference type="STRING" id="6689.A0A423SPN0"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004058">
        <property type="term" value="F:aromatic-L-amino-acid decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006584">
        <property type="term" value="P:catecholamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042427">
        <property type="term" value="P:serotonin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000018">
        <property type="entry name" value="Histidine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF167">
        <property type="entry name" value="AROMATIC-L-AMINO-ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0127">Catecholamine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="152" mass="17912" checksum="A169393552282750" modified="2019-05-08" version="1">MYYLLHRIKNAHDVVDAFNVDPLYLRHDRQGQQPDYRHWQIPLGRRFRSLKLWFIALAHEFESLVREDSRFEIFFPVTLGLVCFRLKNESNDVNDSLLKSINAGGVIHMVPSKAKDTFFLRFAVCSRFTEQADIVKAWQEVKKATEKILTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWD8</accession>
    <name>A0A423SWD8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013263</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002655">
        <property type="protein sequence ID" value="ROT68580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWD8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="486" mass="53242" checksum="30C9F15293ADBFE9" modified="2019-05-08" version="1">MRRAATQGEERKLDEDRAVNPRRVGASAGVREGFGVVSPSPRFPPYLLLLPLLFYSSLLPLSLHSFFLSVLYFRSYSLFSSFLPPLSSLFSLLPLSSRLPFLLSLLFFPSSSLFFSSLLHLSSLLPYFLSLLFFPSSSLSPSSLSSLFFFLFSSLSSRLIFLSPISLLFYCLLPFLPSFLSLSLFQSLPHSSPILLPSHFSLSFPLSPLSLTLLHFFSLFLSSSPFPSLFPSQFPPLPLFPTSPFPSSPLPPTRHFIPLPPFPSFFLPISLPPSFLLSPSPLSFLSSLPSLHSLTLSTPSSLPLPSSFAISLPLPPFSHFPIPYFLPPFSRFPPSPLFPTSLFPSSPLPPTRPLYPPSSLSPPSSFPIFPPPLLSSPSLFPSSPPPSLPSISPLYPPLPPFPSLSVAISLPLPPFSHFPHPLFPSSLFSFPPIPPFLPLPSSLSPSFLPSFSPTLSPLPPFSSFLPSLLLAHLSPPTKTSERRRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZD5</accession>
    <name>A0A423SZD5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Solute carrier family 35 member F5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_012220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002549">
        <property type="protein sequence ID" value="ROT69581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZD5"/>
    <dbReference type="STRING" id="6689.A0A423SZD5"/>
    <dbReference type="OrthoDB" id="6344368at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019374324" description="Solute carrier family 35 member F5" evidence="8">
        <location>
            <begin position="26"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT69581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="493" mass="55271" checksum="83664B5A1134E36A" modified="2019-05-08" version="1">MGRGQRLALGIFVLLLVDIIWVASSELSEYIFNDAGFDKPFFSTYLKTSMFSLYLLGFVFWSPWRHQCIHSNQDESMYQVVDIGDAEELASPEERRLSEPKYVPLKLQDQQEKSSDGESDDSSVKSVRFSKLTEVRQMSEAEAVEAMMSRLSFSASLRAEQLALQAANKLSIKEVMKISCIFCLLWFLGNYGYQIALSDTEAGVVNVISSTSGLFTLILAAIFPSSSVDRFTLSKLFSVLLMVAGVVLVSLEDISLEGATVPVGVVWSLVGAVLYACYMVFLRRKVPTEDRMDFTMFFGFVGLFNTIILWPGFPLLDVLGWETFQLPNKEQLLYMSVNGLIGTVLSELLWLWGCFLTSSLMATLSLSLTIPLTMVVDIFVKDVEYSLIFYIGAIPMMLSFIVVTLLTHYENWDPLMDCITKINRRCSRNNHMYSLVDTEGLERESLIVNETGVDEAEEEDEEEVDTTGINNAIVITDNASASNSMPTMINNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2Z7</accession>
    <name>A0A423T2Z7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative FAS-associated factor 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_010877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002381">
        <property type="protein sequence ID" value="ROT70811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2Z7"/>
    <dbReference type="STRING" id="6689.A0A423T2Z7"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16120">
        <property type="entry name" value="UBX_UBXN3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049483">
        <property type="entry name" value="FAF1_2-like_UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21021">
        <property type="entry name" value="FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="310"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="45035" checksum="A28A1F3066890039" modified="2019-05-08" version="1">MAEEEHLSPFHTEKIVQFQEVTGTEDLGEARSQLENHGWDLEAAVQTHLALGDNRAPTPPIPAQNGRNDHNDTEDGADSGERESTSGSLLPAWPRGSIFSWGYYLLTLPFRITLSSLSSLFLFVYRIVYPYPRRLTDPLGDVLQFIGQYEAEYGQQHPAFFQGSYSQALSHAKSELKFLLVYLHCADHQDTPAFCRTTLSDPALVEYVNNTMVFWGCSVTTAEGYRVSQALRENAYPFLALIVLRDNRMTVVGRLEGPCTPTKLTEQLQLIVRDNEAYLVVARAERQERELTAALRLQQDEDYQESLQEGAEGTVHIVVKLPHGARLERRFLKTDSLEALYYYIFCHPDSPDRFQVTTNFPRQVVPCEPSEANPNPPTFEEFRLPPRSMLFVSDLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3B0</accession>
    <name>A0A423T3B0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002369">
        <property type="protein sequence ID" value="ROT70931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3B0"/>
    <dbReference type="OrthoDB" id="6360577at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15194" checksum="A3F5E154117ACD1B" modified="2019-05-08" version="1">MAVLGIGSVEVLTMLPLPLTCEGIALLPETSLGDRRNVLQCSSRSWQPSTFPGGILVGVRVVVALVAGVCLDVFGRRRSIVAWMGLYFVVAFARSFSPNAESVVFCISLEGAAAQASTLALLLLATSVSTPTSTTTSKPTFKTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3R5</accession>
    <name>A0A423T3R5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Golgi-associated plant pathogenesis-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002336">
        <property type="protein sequence ID" value="ROT71150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3R5"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05382">
        <property type="entry name" value="CAP_GAPR1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000002">
        <property type="entry name" value="Golgi-associated plant pathogenesis-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034113">
        <property type="entry name" value="SCP_GAPR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="155"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="300" mass="33389" checksum="91E8FBF91CE03D79" modified="2019-05-08" version="1">MNKYAKEWAKKLAKDEKMSHRPDNKYGENVFCLSSNSKTFKVKGDEVVDKWYSEIKDHKFGEEPTGTILKSGHFSQLVWKDTKQMGVGKARSAAGTKVFVVANFDPQGNWMGQFADQVPPVGGFAKASGGKSSVFKAKSRKSSSSSSDSSSEEDDFVADCLKAHNDYRKKHGVPLLKISKDLNKVAKDWADTIARKDVMQHRPNNQYGENIYCAWSSNPAHKIKGSEAVDSWYSEIKDFRFGREPADLRAGHFTQVVWRDSKELGVGTARSRGGKIYVVANYNPPGNMVGSFSTKVPSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4H6</accession>
    <name>A0A423T4H6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_010300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Ubiquitinated; autoubiquitinated.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002302">
        <property type="protein sequence ID" value="ROT71374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4H6"/>
    <dbReference type="STRING" id="6689.A0A423T4H6"/>
    <dbReference type="OrthoDB" id="193703at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072572">
        <property type="term" value="F:poly-ADP-D-ribose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033509">
        <property type="entry name" value="RNF146"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13417">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13417:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018996097" description="E3 ubiquitin-protein ligase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="181"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="353"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="41420" checksum="9CE38C0C02AE248D" modified="2019-05-08" version="1">MTELPGTVPKVAILLLVFLCNGRPWGRTPASLRRRVLALSSARTLRWLRPCGIAGEVCTLAGSLEAPREPTGLELTSRGTVPIRPGSYFKEECPRRLMKCQHCELEVIAQEFQRHVDYCESRTELCKGCTKYVQFKYLQFHYEYDHKQYVFLMSNVPVHPSTAAILPNHKENSSDEEGSECPICLGPVTLPLVLECGHTFCMVCVKGIANTTKNCAICRRDIPRDMLMDIRFCREEDIIKNYVNKPREKKTQRSHSVPSRTSSSYSSSSRRVARTTQDYDDMVSALLSSRTSSTSYRYQRPANTHTPPSYTPYSGSESCKDSCKDTDSKDDDCCCSSLRQPPPCRPPAPPLPKRFRRRVPAKRPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T771</accession>
    <name>A0A423T771_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Early cuticle protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002181">
        <property type="protein sequence ID" value="ROT72290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T771"/>
    <dbReference type="OrthoDB" id="6338498at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019028832" evidence="3">
        <location>
            <begin position="17"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="112" mass="12056" checksum="F94E05A98D4DEE1A" modified="2019-05-08" version="1">MYTIFLVACCVCLVAGRPQYAYPAATPVPILVDERIPIDLQGGYGFRIQTGNGIAWQETGAATSKSGQYTFTHPDGTPHALSYTAGVGGFLPVSDLLPTPHPLEPWHIEQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7H0</accession>
    <name>A0A423T7H0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002162">
        <property type="protein sequence ID" value="ROT72394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7H0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="41910" checksum="198565B5ABEDDA65" modified="2019-05-08" version="1">MPTWPRGPPISGVVYMPRRSHQWSHARLVLRLELFHAPTCHVVLRSASSSPWSSDQLGLFTCPDVATWSSDQLELFTCPTWPRGLRSAGVVYMPDVATWSSISWSCLHAPTCHVSSDQLELFTCPRRAMVLRSAGVVYMPDVATWSSSAGVVLHPDVATWSSDQLGLFTCRIPPSAGLFTCPTWPRGPPISWGCLHDPKYHVVLSWILNQLCYMPRRGHWSSNQLGWSCLPTWPRGPPISWGCYMFGPRISLDVVLTCPRSAGMPRRGGSHAVVPAGVVYMPRRGHVVISWGCLHDPNSHVVLQSAGVVYMPRRGKVVLVSAGEEKDKEGVNGGKGNKTEEIGREQPAPHASTASGEEREGDTVHCLSSLPDPPPCVTGDLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7I5</accession>
    <name>A0A423T7I5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002160">
        <property type="protein sequence ID" value="ROT72407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7I5"/>
    <dbReference type="OrthoDB" id="6371270at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="29299" checksum="B801D324322541A2" modified="2019-05-08" version="1">MEGSSGSEEEEEEDNIQETNSTEKDEASNRQEKRQTGTDSVVPDYLLKKIKVEPGTESAKEGAQEPKSVMELLELQMRARIIKTMLEKDDGKKLTEDAIAAVIGNTKLTDDLRKVGEEKVIKDSEKNTVSKERKESETQPERRSRSSSRRREHRPDGKRSRGRSNPDKRKRDRSGSRNYEEDKRIAKQSQESDGQVSGGGVTAGAGPEATAEVHQEPEAEGRGGGGGGVGVIAEVIVEATVEVEAEVVEVTPGVGVDLEALIRREME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TE35</accession>
    <name>A0A423TE35_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_006754</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001852">
        <property type="protein sequence ID" value="ROT74729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TE35"/>
    <dbReference type="STRING" id="6689.A0A423TE35"/>
    <dbReference type="OrthoDB" id="10067491at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051392">
        <property type="term" value="F:tRNA cytidine N4-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 9 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="12">
        <location>
            <begin position="9"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="11">
        <location>
            <begin position="248"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="402"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="14">
        <location>
            <begin position="634"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="535"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="861"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="535"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="888"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="899"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="503"/>
            <end position="505"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="510"/>
            <end position="516"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="593"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT74729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="908" mass="101600" checksum="B61BD23718A39BE0" modified="2019-05-08" version="1">MEKVTADGRIKTLIENNVKLGHRALLTILGENARDQVMIIHHLVSKASGERPSVLWCHKKDSDVPRQSRKQLKKLEQRLKSGKCDISQENAFHIFLLSTSVRYCSLTDTQRVLGNTYGMCVIQDFEGLTNTLCRVVETVSGGGVVVFLLPGMQSLRQLFSLNMDSHGRLKTYSHPKVTPLFNERFVLSLGWCRSSLIVDDKLQLMSELPSLAGPVKLWQSLSYKRWSLCKNNCRTCRRALRMQTNHFRSFDALGYEEQSDYEIIQSTNEEFNEAIVRVNVFREFRQTIQYVDPVDANKLGQCELLVIDEAAAIPLPQVKALIGNYSVFMASTINGYEGTGRSLSLKLLQQLRQQSSSAGATAVKSVDISSEIISNRSLHELYYVNRDVLFSGHKESEDFLHQVMSLLVSSHYRNSPDDLQVLCDAPAHHLFVLLPPIISGMTSLPPVLAVVQVCLEGGIPKSVSDGNKSRGERPSGDLVPWALALQYLDTSLTEQVSARVIRVAAHPDYQGMGYGSRAINLVSDYYNGKHISLEDEQDSGVGTDEEDKDSNAIVPRKSGKPLLSKLSERVPESLDYLSVSYGLTLPLMKFWCRAGYIPLYISQVANKVTGEHSCMMIKLMDASEGESPLARNKWVKNASQEFLRRFISLLGGPFSNLPSLLALKVIQSHSTTQEKEIKWKELKSMVSGHDLHRLEKYSNNLADRYLVTDLLPNIATLFFLNKFPSVHLSPVQSGLLVGLGLQMKTMDNVVSTLDITLESALGQFNRAIRRLLKAMTSIQESSLAQHLPAPVVPEFVPVDITLDQDLNQAAEDFERDQKKKEKLQEINSLIMGDVRKYRIQGDDRAWESVLEGGAGASVTIKSSKRTAKMTEKELENMLEAPTKKKKTKDGQGGKQVKDKKNKKLGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF87</accession>
    <name>A0A423TF87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006352</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001809">
        <property type="protein sequence ID" value="ROT75122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF87"/>
    <dbReference type="STRING" id="6689.A0A423TF87"/>
    <dbReference type="OrthoDB" id="6261922at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000038">
        <property type="entry name" value="Serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF129">
        <property type="entry name" value="LP15124P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="134"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="44089" checksum="4C252B0098656CAE" modified="2019-05-08" version="1">MQMFGDVDDDGPGESSCHSAPWLSPEHTYRRISSLTYCTRMRVLAAVLALAAVASAVPRVRRQTEPQPRLGGNNTEATRSATPEPARSSATEFISECPSFLDVCCTDPTRKPPPPPKYVAQCGRRNEEGVNARIVDFPANQAQFGEFPWMAAVLRTEYSEDNVEEKHYVCGGSLIHPQVVLTAAHCVYNINPTTLNVRLGEWDTQKAYELYPHQDRNVGYVVTHREFNPTNLFNDFALLFLDSPVELAPNVDTVCLPEQGEIFDGSYCWATGWGKDRFGKEGVFQNVLKEVELPAVSQYDCQESLRTTRLGKLFKLHPSFTCAGGVAGVDTCTGDGGSPLVCKGLGNSYVQAGIVAWGIGCGEDNVPGVYANVPGFVNWIKNNVNTILLQEFNYDNANYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFY9</accession>
    <name>A0A423TFY9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001778">
        <property type="protein sequence ID" value="ROT75382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFY9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019229284" evidence="2">
        <location>
            <begin position="21"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="483" mass="51195" checksum="9261CB63DFF58C86" modified="2019-05-08" version="1">MSFSFLLPFSSSSILCLTSALLSSSPSTPFFYFLLLSPPFSHTAVYLPHMLCLTPPLSPCPVLTSFPSPLSPPPPPYSLIHANPWLLYPPPLPSHGTPPFPFSLFIVFAPPPSFSPLPPFPPSLWSASITCPLSTLLFPSSLFHSLLSLPRFLTPFLPSPSSLPQLLLFHFPPSILSLPPAPSLLPSLLPTPLSSLPSSVPPSLPSSLPSSPSSSPFLPPSLLLFPSLLLVISSFPSSLLFALLSFLLPLSSPTSLSSLHSHLPILSFSPPPPPHTFSPFASHHLSSPPPHHFFIIALLPPPSPLFSPSPSPPPHPLPSLSPPSPSPPPLPYHSPPPPSLPSSSPPFTHPPPLPSPSPPPLPFPFPPSFLLTFPPPSSSPFYPSPFPSSSPSLSPPLPSHHPPPPFPLTLLSFLLTLPSPPLFPLLHPLPSSSPSFSPPHPITLLPSLPLPPLHHSPSHLPSPLRSPSPSPSPPSHASTKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THZ7</accession>
    <name>A0A423THZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001695">
        <property type="protein sequence ID" value="ROT76079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THZ7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="40544" checksum="4A3F82F291246573" modified="2019-05-08" version="1">MTPDTRSSKYTTPSSRTPCAVSTPVGTLCPSCSLPFACCLVQWLFVRVGGAEESPQVQKKPAGRSRRSPRGRRRSPRGQKKPAGQREEARGAGGPEEARGAGGPEEARGAEGPEEARGAAREEQPEEARGAGGPEEARGAGGPEEARGAGGPEEARGAGGQKPAGQEPEEARGAGGPEEARGAGGPEEARGQEDQKKPAGQKDQKKPAGQKDQAGRRTRRSPRGRRPRRSPRGRRTRRSPRGRRTRRSRGAARRTRRSPRGRRTRRSPRGRRTRSPRGRRTRRSPRGRRTRRSPRAGGPARGQARSPRQEDQKKPRGSQKKPAGTRRSRGGPEEAAGACGAGPEEARGEARGQGILLRTKLPTSPPSKPPFPLRRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJC4</accession>
    <name>A0A423TJC4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001646">
        <property type="protein sequence ID" value="ROT76545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJC4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="20195" checksum="AF72295FE8287804" modified="2019-05-08" version="1">MTTQTHSGPVETVPPGTRLFASYRERPRTRKDACPLRQTTDRPLGRKHQRTSNRIEAAGKMAPKISIMALYLLLFVLAAVDAKPPADDTKQPVTGRVAPAEISEGLQEIDNHGRITVPEGQSLPPHPAVGPGHNAPPNSIDDGGSGPVHYSHNTHNTHTQHPDTVFRSRQLSAAHWLPRQSQEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKM5</accession>
    <name>A0A423TKM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative neuronal pentraxin-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_004349</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001576">
        <property type="protein sequence ID" value="ROT77020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKM5"/>
    <dbReference type="OrthoDB" id="6359554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018968733" evidence="8">
        <location>
            <begin position="16"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="570"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="600"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="629"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="9">
        <location>
            <begin position="128"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="10">
        <location>
            <begin position="373"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT77020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="676" mass="75675" checksum="A40960B71400449F" modified="2019-05-08" version="1">MGIWQLILFLYLVFATTDTRVTTVYELLANGKEYASISLHPAVLSQLGDYHTNASTRTVLSEEQSENKAENGPYVDPMSTMLPHSAMGAIDGLNSSLDKNETLTPERIYLTYGRRTTHIPARLYDLDQWHRACHVGARSHNHTFYLDGTPLSSWVWGHDPPLLTGGALVLGQNPGTFQGGFNNKYGFKGKLADVNAWSRALTPADIQRQSECRDDPPAEGDWISWSNASWRLEGRVRGLQENPCREVGPFLVFFNTKVSLAEAFHSLQILGLTLFLPVSQEDSENVQQLLTKYGSNCFPSGARDGSSSIFDNNTSLPLTLSTCLPSEFVCDDGSCIDITQRCDLVSDCADWSDERGCILATTPKGHLNTLPPSRDLHVNASVYLEVITVDLLQMSLLLDLKISLLWYDPNVKFLNLRASSHTNTVPRLHSGFKLWTPSVTIEPLLGFPARKSVLVVCRESNGTVIEDDTVYEGRENPLRLLIHLQPEVRCTFNFQWFPWDEQICLFNLSLVNLDQRNMKPQETSDAIATSRLILEEYTVTNLSLFQHEGATSRTVLVQLKRHSLQYAYDSYFPTALLLALGYGTLFLPAEPFNDRGTMSLTTLLVLVALYTDSLRSLPDVNYNTYLDVWYIFSMAYLSLIVATHIVSRGPKVLLYSQLLFGVGLVVFVVGYAARIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TP91</accession>
    <name>A0A423TP91_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001407">
        <property type="protein sequence ID" value="ROT78259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TP91"/>
    <dbReference type="STRING" id="6689.A0A423TP91"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="42868" checksum="05A47E7521657C98" modified="2019-05-08" version="1">MLDHRYAASQAYLGLILPHTLGDPARDREGRALTPLANPSPAAPPPRQLPFPGPGRRVPATYRVLLIKVCSYIVHVLMLHVAARDLFARYHGALSGDITALKYSLQMSILNRPLPPEDLPTSRHAHLSERIKSVKEAMILPIQNEAYDPAASPETPVEDFNSHTYEDILATAILNKVLESCEGERPDEVTIEVSHEVTSTDTDSGMSGGAKESRRGRLKRGELSEGGSEGSEERSLTPPRRSSRRPPTVSPDQGVVTDDSWAQAAAGDGPPLQFKVSVSDSGGSWRGSRCSLDDTRERRRREKVTRTATVAEDALLPSLNIPLPDPSHLASRRVSFPELGADIVHDSCSDTDCCQVNRRHGDGQRHLGGELALQAPATGAWRRRRREHCGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPJ2</accession>
    <name>A0A423TPJ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001390">
        <property type="protein sequence ID" value="ROT78376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPJ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="656" mass="71275" checksum="32266443C43EE27B" modified="2019-05-08" version="1">MVDGNGQPESTLTTNNDSEPLTSDGTYNEIDNKAVSTLCILPEPSCRTRKKKGKKARANIGPKSAEDPEIEQRVPRIAGEVQVSGTNAILINGNNYLIIRGGVGGLGAGPPAGAVVRGLASTAKILIAKDDSMKQARHQQEQQQRAGKTGFFLPRALKSGRTLVLRSNGPEQENGRPPKVRDQRPDASAHRSSSGIRISSRYRSLSEKKSFSERRNSDRKREPSGRKSPGGNRTPIERRHVSGGRDAREKKSLSEKRSAAAAKSAGGSRHSSGSRSSSAQGSAMERRGKMAVASGQEARAKGKRRKRGAKHKKKARAKQGRWTDSGTKEAAREKPIRKSTSRRRSRSKKTSARPSRPLANRCSIDEQESEEQTEIIVNENEEPIVTKSRQQTAESARPLIVTGNAKENVVCKRGFVLPASEKSDQRQDHVIIRGIDQSMINKGRPIIIRSGGQQNVICGRPSGGGTYKLKLNVSGLVQVKPTIVIISTGKGKNFFRRSGAVGNQDPRHQNILRHTARNGDEDVAANRRCLLAAGGRGKTARDAGVKEDPGCGCRMSLRIDRWTVGERSRKASRKQADSRSRSAEGPQRPAWKDAIVQLFLTAVLAGGVLCQSQPQALVSCTMISVFIPRGCLPFSRTCPAGKSCISPFSSEFQDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQB3</accession>
    <name>A0A423TQB3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mixed-lineage leukemia protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002629</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001348">
        <property type="protein sequence ID" value="ROT78658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQB3"/>
    <dbReference type="STRING" id="6689.A0A423TQB3"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20901">
        <property type="entry name" value="CC_AF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15672">
        <property type="entry name" value="ePHD_AF10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15574">
        <property type="entry name" value="PHD_AF10_AF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000042">
        <property type="entry name" value="protein AF-10 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000053">
        <property type="entry name" value="protein AF-10 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049773">
        <property type="entry name" value="AF10-like_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049781">
        <property type="entry name" value="AF10/AF17_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF164">
        <property type="entry name" value="ALHAMBRA, ISOFORM P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="12"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="79"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="209"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="458"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="635"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="731"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="685"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="323"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="405"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="481"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="731"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="776"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="798"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="823"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="859"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT78658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="891" mass="94398" checksum="58DAF411CEF1CA1F" modified="2019-05-08" version="1">MKPQESEPKEMVGGCCVCSDENGWTENPLVYCDGQGCNVAVHQACYGIVTVPTGAWFCRKCESQERAARVHSGGRRIFSQRCELCPSKDGALKRTDSGGWAHVVCALYIPEVRFGNVTTMEPIMLQLIPQERFNKSCYICEESGKESRAIIGACMQCNKSGCKQHFHVTCAQSMGLLCEEAGNYLDNVKYCGYCQYHFSKLRKGSHVKTIPPYRPVPLEAGGSDEEKSSAYESRDPKMKKRTGRPPGGSIKPSSREGGGKVGDMMASASGNSGSSGSGDRHDRGQAVGSDGLSVTPGSSGVTLSTGSNSSILQGKVESVAKMSESSPMNSASQASAPVQSLSSLQITPVPSSAITSAPSLSRPKVPEAPPHVPVSGSHESPSQLSAVANPPQANSQAHVPVQSEVSKDKQQEHNRKLRRNGPRTPSGNSNFGDTESIVSNDDAQSSDLVLNICEEKNLSAEKESNKVPSKPVDSSDDGGSLNVQFTPNVSTLSSKASDPFTPTVADFAPNENVKRGRTSSQDRGRRAKRGMNKRGRPGGGRDGGGRDSGASSPDSFTSESAPQPKRGRKKTESKDNLTTVITNGVGANTLLLGNQLNPASAVAQKMTDTLHAELEAHSIYKDEEEKMTNLLVGPAIPGKKENPNGSTSAANSQPPPFPQSLEQLLERQWEQGSQFLMEQAQHFDIASLLSCLHQLRQENVRLEETVSSLIARRDHLLAVNARLSVPLNSPSTANANASSNANPAPSSVSGSSSSSSSSSSAPPPQPPSAATAHAPNPRPPSSGSAPAPPPPRPHSQGHHPPGGSTHPSGTTPVGGSSGHRGASPHDRRGPSPHERRGTSPHDRRGPPPPLPVENGLGEPEYRYRSPGTEHRQQSPMLPPVTHNKISPVQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSS0</accession>
    <name>A0A423TSS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001241">
        <property type="protein sequence ID" value="ROT79460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSS0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="42720" checksum="D54E286B3729E9C5" modified="2019-05-08" version="1">MCMEPKLCPLPDTFSQQHFLLSPKTYSPSHPKSGPEEHQTAYDCTVSTTSTLSSSVRFSFHLLFSLPSLSPSLSPCLSSFSCLSFLSFPLNASHATIPLSENNRATIIHRTPLSCVFSFSFYQHYSIVNTSRNAVPLSTPTILKFHIQHQYHSTVNVSYATIPVSSPAMLLFRRQHHHAVIPCRHQHQPFCLFTLGASHAPIPLSTSIVPTVLVQHQPCCYFTINTNHTKIPVNTTILKFLSTPAMPNIPLSTSIMSAPSILPFPLSTPTVQPSHRQRQPCYHPTANTISPFPSQRHATILPYHHQPPTPSKLTSTPTIPFSTPALPSRPLAATERPAWTISPLSVARHDRSYKVLKIAVIRGGSTPAPSVSAKLGFHKRLRDNFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT47</accession>
    <name>A0A423TT47_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WAPL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001652</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WAPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001216">
        <property type="protein sequence ID" value="ROT79628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT47"/>
    <dbReference type="STRING" id="6689.A0A423TT47"/>
    <dbReference type="OrthoDB" id="78088at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000374">
        <property type="entry name" value="Protein wings apart-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039874">
        <property type="entry name" value="WAPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022771">
        <property type="entry name" value="WAPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012502">
        <property type="entry name" value="WAPL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22100:SF13">
        <property type="entry name" value="WINGS APART-LIKE PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07814">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51271">
        <property type="entry name" value="WAPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WAPL" evidence="3">
        <location>
            <begin position="617"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="402"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="548"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="564"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1183" mass="131242" checksum="9850D9347E46F17C" modified="2019-05-08" version="1">MTGRYSRTYSRKKAAPPPISQFDKLVTEPGGSSTKPSATKTAGHVGKWGITSFTSIRSINGGFGKDDSNKRSHPDDSPPSSIADDAFSFDGGSTANGASLQVKPPNSTYSKPRKFFKSRNVDVVSEPVAAKPSIIEKTRAKGYDGLSNLKIPPLSSFETPDSSQGTVKDSVDLSDQSAFDKLVTSGGNKSNFTEAPSGQKSSSGIKLKIFKSRNVASCSQETYSSTVELPSDDSRANSASTSVASSPSTKDLSEENRDSSEELMPSSSPPAEYKESQVSSTSLISQQNAYHSPERLASPDRTINSTYDSSFEFAGLVDQRTGLPILGEDSDYSFSGTKSNSETPQLGSKRTYGTKVSKSRELNKYMSNKMVSLSDIDTQPNTLSEVCSGSLTDDFDIFGVGSSDFTEPQKTPPPVTGRVDSPTVSSGGGGESDNFDLFSTDFDENDIEDRTNIDCGTGVLPVQKDSPSMGATQEMEDLLFSSQGSLMTTQSSATSSCASYKRSNSTKSEPEGVKKPEQPPLVKKRSIFKSRDADRDAKKRATYRHKWHDQEEKDDAAKEKPALQSSQSVTSAASSFDDFDFDPPATLKRVQTWPGSSSTADLDDSYDNQTVTSVKCAKNAKQYYTVVKNVKRTHQLQESGEFQEFNDDVEYFLDALRSSMPVSTRCLAALNLAQKCMVPAFRMHLRAHGTVIKFFSALSDAHSDHRLAICAATVMFTLSQDRLNMDLDRDSLELMLNLLDTDADASDNTLVDMAEVDHNKKKIRELCRDMQKKGHAKHLNLNNITAGHLAMETLLSLTSKRAGEWFKEELRELGGVEHLIRTITHCTQMFTPDLETWTHPLLEKLSKVDRCLKVIENVTHQNTANQEYLLTYQDGIFPEKLMYLYRLCHVEVPLYPVSDTENQKTMVGGMSTGQLLVQTLLTTIKVLINLTHNSGKEAMGSRLLGNEQEVYDITLYCLLIMPRYLAHDTRFEILILACCLLLNLVEHSKSNRNLLMKSKAPEFLDDDDNDCFGGKGERKGAMQALVELFYRCEESARQQEAHTDDLIDNDLSEKAQKEDDRKDDELEETVAKLLQKAGHHMEDTLVAAYTALLTGYCIMEDEECEAEIRSMLPDANFNLMVVVLKKFLHFMDLTATTSLLRSLKPTQRVVKYMEKLDRTEQEEAEEERKKQEQKELEFDAFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTH3</accession>
    <name>A0A423TTH3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001552</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001198">
        <property type="protein sequence ID" value="ROT79721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTH3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="755"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="839"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="933" mass="106831" checksum="BB24D5C55D38CD0C" modified="2019-05-08" version="1" fragment="single">LFSILSFSPISIPIHIFHLPSYLSLLSPYSHSHLHLPSYLSLLSPYSHSHFHLPSYLSLLSNIPIHIFISHPIFSLLSPYSHSHFHLPSYLSLLSPYSHSHFHLPSYISLLSPDSHSHLHLPSYLSLLSPYSHSHLHLPSYFLFSNSTIFHPIYLSLHISIFPFTSSSPILSFSPISILPFTSSPILSFSLYTPIFHHIFTSHPIFLSYLHIPISHLHLHPIFLSYLQYFNSHHPPSTSLYLPISIHIFISHPIFLSYLHIPTSSILSFISITPITSSPILSSLLSPYFHSLISQPISLSYLHIPIHIFISHPIFSPTPLFPFTFSSHILSFSPISTFHIFISHPISHPTFLSYLHISIHIFISHPIYLSLLSPYSHPRLHLPSPRPPIFSSPTRPVTMSLSSKSYLSLLSPYSLQIFISHPIFLSYSFISIHILSPILFIHSLHILIHPIFLSISNSFTFSPPIYLSLYSPHPTHIFISYLSPLFSLSIFTFFTFSSPILSFSYLHIPTAHLHLPSFFLSYLHISHLHLHPIFLSISIFPFTSSSPSYLSPFSPIHIPIHIFISHLSFSPISTFHIFISHLSFSPISTFHISPPSYLSLYLHIPFTFHLPSYLSLLSPHFTSSPSILSFLSYLHIPIHIFISHLSPSYLSSYLHIPIHIFISHLSPSSPISIIFTFHLPSYLSLLSPYSHLHLPSYLSLLSPYSHSHLHLPSYLSLLSPYSHSHFHLPSYLSLLSPHSHSHFHIPSYLSLLSPYFIHIISHPIFLSYLHISIHIFISHPIFLSYLHIPIHIFISHPIFLSYLHTPIHIISHPIFLSYLHISIHIISQPISLSYLHIPIHIFISHPIFLSYLHIPIHIFHLPSYLSLLSPHFTSSSPILSPSYLSLLSPYSHSHFHLPTYLSLLLSYLHIRIHVFISHLPAHLYLARRPDLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU65</accession>
    <name>A0A423TU65_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_001275</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plus-end directed microtubule motor that may be used for anterograde axonal transport and could conceivably move cargos in fly neurons different than those moved by kinesin heavy chain or other plus-end directed motors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001167">
        <property type="protein sequence ID" value="ROT80003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU65"/>
    <dbReference type="STRING" id="6689.A0A423TU65"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01371">
        <property type="entry name" value="KISc_KIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000029">
        <property type="entry name" value="Kinesin-like protein KIF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF50">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="16"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="650"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="409"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="655"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="103"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT80003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="676" mass="77187" checksum="B73D2644994BFA72" modified="2019-05-08" version="1">MAPDKDRGAAVKERENVRVVVRVRPLSEKEIHSGHKSMVESDDLNCSLIVTNPSAQSGEPPKVFTFDSVFGADSKQVDVYNLAARPIVENVLEGYNGTIFAYGQTGTGKTFTMEGVRSVPELKGIIPNSFAHIFGHIAKAEEDKKFLVRVSYLEIYNEEVRDLLRQDQSMRLEVKERPDVGVYVKDLLTHVVHNADEMDKIMTLGNKNRAVGATNMNAHSSRSHAIFTITIECAERGVDGQQHWRVGKLHLVDLAGSERQSKTGATGQRLKEASKINLSLSTLGNVISALVDGRSTHIPYRNSKLTRLLQDSLGGNSKTLMCANIGPASYNYDETISTLRYANRAKNICNKAKINEDPKDALLRRLQDEIKTLRGQLEATSQLYPSFLLDIKGSRFTQSPTEANNVAAIRKKIEEERKMLSERKDLEEEERNKVKSDLDRHEKELKKAQKEQEALKQRLQGLERKILVGGENLLEKAEEQERLLEESAKELEERRRHEEQLRHAITQKEAERIDLEERYTTLQEENAGKTRKLKKVWTLLMAAKSELGDMQAEHQREMEALLESVRHLSREHKLHQLIIDSFIPLEYQDMVERYVHWNEDIGEWQLKCVAYTGNNMRKQLDNGDAEKENQNQDGDMWQVYKTYSPEVYTKPAAKPLRKKSGIPRPKHARSARKYDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TX19</accession>
    <name>A0A423TX19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_000267</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001042">
        <property type="protein sequence ID" value="ROT80982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TX19"/>
    <dbReference type="STRING" id="6689.A0A423TX19"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11054">
        <property type="entry name" value="CYP24A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000006">
        <property type="entry name" value="Cytochrome P450 302a1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050479">
        <property type="entry name" value="CYP11_CYP27_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279:SF120">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019365653" evidence="11">
        <location>
            <begin position="18"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="13"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT80982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="549" mass="62597" checksum="5170FB54DF03F94C" modified="2019-05-08" version="1">MLGQLQILLLSFTPSSPSSFSPTPPALPPPDPPLPRRVPCDNEPRGRDTESGRFGRRGRPQAAGEGDVDLRLGTPDSRPRCRPCVRGRGAEFYEHKIHQVFFRMVDQYGPIVQIKMPNWSRGVLVTRPEDKETVLRATKDNPLRKALPSLKKVRDEAMENFFDKNGGLLTEQGDKWWRVRRGVQTPMMRRKNVEAYLPEVDAITRQFMDRMASFQEELGEMPEDFLQELYKWALESVSVVALSRRLGCLDPALAPDSEPLKIIQIVGDLFRTLNACEFTGPLWRMYPTPTFKKLERMHQELLEMALTNIRATEASLKEALEKPGAEERELTLMEQLLLRPELSHKDVVTLILDMIFAGIDTTSHTMAFALYLLAKNPEAQRKLQQEVDQVLKDNPETLTPAHVAKLSYTKAVVKESLRFFPVAMGFLRELSSDVVLSGYHIPKGASVLMLNYEDIQDDPAFPRPREFLPERWLRGSELAASHAFALLPFGAGTRMCVGRRLAEQEMYVFLARVMQRYTVSYNYGDMDSTMQLILKPSQPLKFSFSERRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYP2</accession>
    <name>A0A423TYP2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycolipid transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_025246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000951">
        <property type="protein sequence ID" value="ROT81573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYP2"/>
    <dbReference type="STRING" id="6689.A0A423TYP2"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3520.10:FF:000001">
        <property type="entry name" value="Pleckstrin domain-containing family A member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="3">
        <location>
            <begin position="64"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="28696" checksum="9C329A02BF7ACA17" modified="2019-05-08" version="1">MFVPLDESSAFSPSSLECSDSSTEPEWHSRDKQSEKMTLPQPDSPNFFSQISPTFPGVTQDGKIETEMFLEASKSFIQIYDLLGTAFYVVKKDMSGNIEKIYKAYNCNPEKYKYLNDLICEEKDVQDSVTVDALLWLKRALEFTVMFINGICDEFEKGTGSERLDHLATEAYNVTLKKYHKWIVQNIFKMVVKSVPTRSVLVKALYFGKSGPEETLFKDCRVYMKQLETNLRVIVQMYDEWGLNNDNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U036</accession>
    <name>A0A423U036_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">I-connectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000886">
        <property type="protein sequence ID" value="ROT82073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U036"/>
    <dbReference type="STRING" id="6689.A0A423U036"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF4">
        <property type="entry name" value="MYOPALLADIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immunoglobulin I-set" evidence="1">
        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="205" mass="22661" checksum="6810CFFC1CD8A7C0" modified="2019-05-08" version="1">MGEAQSSVSFKVEGKEGVITESARPEGLEKIRELEDSARVGRQVSEEVRTFQRPVFTQPLQNLDNLTENETAHFECRLIPVGIPTSSSRINRTHDFGYVALDITGVRADDEGIYMCRAYNDLGEAVTTASIKIKSHATIQMETQHPEGMKKIQALEDRKPAGRGDEADKVYEKPVFTATLAGPAQIMEGQSAHYECRVVPVVTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1I2</accession>
    <name>A0A423U1I2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Sugar phosphate phosphatase</fullName>
            <ecNumber evidence="13">2.1.1.-</ecNumber>
            <ecNumber evidence="13">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_024299</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 13">Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:35603"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:28002"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="domain">
        <text evidence="13">Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="13"/>
    <dbReference type="EC" id="3.1.3.-" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01000807">
        <property type="protein sequence ID" value="ROT82540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1I2"/>
    <dbReference type="STRING" id="6689.A0A423U1I2"/>
    <dbReference type="OrthoDB" id="541375at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097023">
        <property type="term" value="F:fructose 6-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103026">
        <property type="term" value="F:fructose-1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10880:FF:000002">
        <property type="entry name" value="Acidic residue methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039763">
        <property type="entry name" value="ARMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260:SF6">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="14">
        <location>
            <begin position="19"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT82540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="475" mass="54072" checksum="D47E9EB52080FE51" modified="2019-05-08" version="1">MADPQPLSGRRVGSFAYLTIKDRLPVILTKVIDFLCREKVSIGKQYGEAAQEGCKEVIGRLSQLKNEMQTNKPFRILQADPSASPHDDSDEYNRELEKFTIENEDQPKWFTAPWLYAECYMYARIHEAFYLCDPLRGFDPFLVQKQKALVDSKTAVDCLTKRVVTACNSVSNFTQQLLKQYVIQLLEVCLWGNRCDLSISGGADRAQESDIFSSLDKLRPQILDNNADLLWQLLVSLPEDQRDLVLVLDNAGFELVSDLCFLTFLMESALATSVTIHTKTRPWFVSDTLHSDLMWTIEKLREFGDSNAEMANKWANYLSSGQWKISENKFWTQHHDFASMNEVDPRLYSELCKASLVIFKGDLNYRKLTGDLDWPTNTSFQRALRGFSPAPILVLRVWWAYAERTAAAAMEHQSMADPAVTAPAHLTNTHSTTTLIRDVTFDLYNIPYLMHCLLSLSNPVSHSPDALPRNLFVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2I3</accession>
    <name>A0A423U2I3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative serine/threonine-protein kinase par-1-like isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023936</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000762">
        <property type="protein sequence ID" value="ROT82888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2I3"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342:SF12">
        <property type="entry name" value="DEATH-ASSOCIATED PROTEIN KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019550658" evidence="7">
        <location>
            <begin position="26"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="42052" checksum="71EA4C7E6DBA21DB" modified="2019-05-08" version="1">MILTRAPSVRSVGVLTYVLLTGTLAFGGDTKQETFLNISQGHVDFPEDLFGDVSEQAKDFISHLLVVEPSGRLSVDEALEHQWLRTAPRPRSRPRSCPWPAPRARPEGHAAGARRRPPQNAHRPSLREPQGRASPRVRRHGEAAGRGASSPLLRARREASPRRPRRRGPPSTGSSSTCPTSNLKAASAGDGLSTKAKAEAPAPSAGAGSPSRARGRRGRARGPLRPRGRDASLALNREARGRPWRLRERTRWARGRTRRKQEQNTDGGGAALSSPCRRARLAQPRQGPLRQREIAKAPEAKRLAGGGKGGQGEQGARARRQGQPQGEAEAVAAVPAAPGLQGRPALADGAAEVRAHPGLRGQEDREGHDLLTRLRRQERREEGGFRIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2M1</accession>
    <name>A0A423U2M1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Iodothyronine deiodinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the iodothyronine deiodinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000755">
        <property type="protein sequence ID" value="ROT82965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2M1"/>
    <dbReference type="OrthoDB" id="6379755at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004800">
        <property type="term" value="F:thyroxine 5'-deiodinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042446">
        <property type="term" value="P:hormone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042403">
        <property type="term" value="P:thyroid hormone metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000643">
        <property type="entry name" value="Iodothyronine_deiodinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11781">
        <property type="entry name" value="IODOTHYRONINE DEIODINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11781:SF22">
        <property type="entry name" value="TYPE I IODOTHYRONINE DEIODINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00837">
        <property type="entry name" value="T4_deiodinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="1" id="KW-0893">Thyroid hormones biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="14259" checksum="870FDF2332B9EC5F" modified="2019-05-08" version="1">MASLGEFRKLTEDYADVADFVIVYISEAHPTDGWAIEGNVFQVSNHKNMKEREEAARRMVTLEPVDCPVLLDRLDDAANKAYAALPERLYIVHGGSIVFKGDQGPLFYKVHKVEDWLKAYTEKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3S2</accession>
    <name>A0A423U3S2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative serine/threonine-protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023452</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000697">
        <property type="protein sequence ID" value="ROT83358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423U3S2"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342:SF20">
        <property type="entry name" value="MYOSIN LIGHT CHAIN KINASE, SMOOTH MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="97"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="766"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="909"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1240"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1295"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1611"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="909"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="943"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="959"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="971"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1128"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1153"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1253"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1295"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1312"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1364"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1391"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1424"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1441"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1468"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1506"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1611"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT83358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1637" mass="185202" checksum="ABDA869FB2DAB4F9" modified="2019-05-08" version="1">MIVVDEREPVGGSHLVCSRLTALTVRSLSAAAKVRSRARHALQAKFPSAGALVTEYASQLRPFRRGSLPEDRSVKLPPPFPPRNVEVKEDVDMRKYYDLKKEIGRGRFGTVYLVTDKTTGQKFAAKFVNTKRNQDRANVEREVEIMKLLNAERPHPRLIQLYDAFDMDKEMCLVLEVVDGGELFERVIDDDFVLTEKACAIFMRQVCEAVEFIHSKNILHLDMKPENILCLSREGNRIKICDFGLARKYDPRKKLQVLFGTPEFVAPEVVNFEPISFGTDMWSVGVISYVLLSGLIIHLTIHKTPADYPAFYYPPHYPQNSRRLSGLLLSTPLSTNSRRLSGLLLSTSYPQTPADYPASTSLSTNSRRLSGLYYPPHYPQTPQTIRPLLSTSLSTNSRRLSGLILSTPLSTNSRRLSGLLLSTHYPQTPADYPAFYYPPHYPQTPADYPAFYYPPTIHKLPQTIRPFYYPPHYPQTPADYPAFIIHPTIHKLPQTIRPLLSTSLSTNSRRLSGLYYPPHYPQTPADYPFYYPPHYPQTPADYPAFYYPPHYHKLPQTIRPFIIHPHYPQTPADYPAFYYPPHYPQTPADYPAFYYPPTIHKLPQTIRPLLSTSLSTNSRRLSGLLLSTSLSTNSRRLSGLLLSTSLSTNSRRLSGLSPFMGHNYVETMTNVTHNKYDFSDEAFNCVSDDAKDFIEKLLVWNSHPNSPYLIGTPLTQLPPELQRIAREEGWSSRASFSNKDEFSHYTFEQRQPSPRRLASQLEVKLSQLKEDNDGRKDKDQDKAGVDNEKINKKASDTLPSDKHKKDDNDKLSVSKPEKNEKLEKERSKTPEITKKENEKNKKTEETHETAVKSKDNEKPTGGLQKCSSTVFLDDPKKAYQEYQKMVNEAIKKKQEEKKALEERIKARQEELEREASKDYDWRKNKEKKETTETRKTSVTNYLKAKEATNVADEKRSRGSKSPVSVYSSTKATDEQLDDNKQAYEDYKRRVSRSEKDAKKTEDAGKAKPREPLRRPEIIALQNEELGGSTARQRKKSLSRLDTGDSLSDRSSRGSTPKSPGLDGATSPKYDFDLEAGQSRSSTPTKLKKQPSRDVPLQAKNTDQEERPGTPVRQKPSRDVPMPYITVEGEDRYSRPRRGSRDLTPDSPLPHRKISTEERPPSRESRPGTPLSHRRPSRDVNISSGQLDRLVQASGLDSPELTPDQPQMWPDLIVCPQGQDDEECQDYKDSLDVPIATLMKSPSGTLRQVPEVTILQTDKSNASESKTLDSEGNSNDPTYVPSNKLVAWILDIGNVQNQRQAPFSTSDRVSQWEGKEPSPKPGERSPREKSPRLSTRSPVPSDKHRDKSPAQPRTPFLCPLSREPSSVSLKSSGSLENACIQTPWGELKRSPSRSTLSKSPSFEVPSSKAKDSTDPGNGGSDDHMSVGSSTRSPSPRSYSKFHKQDSMEIQERKDSLTSPRLTGELPPKPPEKMQRSSKEENLNIRSQAKKDDWKSATLPRQAKLAKQGSTDNLKNYTTEKRSSLLSVEEGNTDSLKRKSKFPPSPNQKRKLGSCLLFSAQDRISQFEKKQPSTRPPQRPITRTRSSMVFTTTAQENGLENRLSCDVNKNALTSSLNSSYTPTRRPPPVGPQRSPTFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U600</accession>
    <name>A0A423U600_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Down syndrome cell adhesion molecule</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_022668</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Synapse</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000588">
        <property type="protein sequence ID" value="ROT84147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423U600"/>
    <dbReference type="OrthoDB" id="5969272at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="CDD" id="cd20956">
        <property type="entry name" value="IgI_4_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20958">
        <property type="entry name" value="IgI_5_Dscam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000017">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Down syndrome cell adhesion molecule like 1"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="nephrin isoform X1"/>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056754">
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    </dbReference>
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        <property type="entry name" value="PROTEIN SIDEKICK"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00041">
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        <property type="match status" value="5"/>
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="IG"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0770">Synapse</keyword>
    <keyword evidence="3 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="2210"/>
            <end position="2231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="2266"/>
            <end position="2289"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="701"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="772"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="877"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="964"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="1062"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="1153"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="1303"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="1402"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="1503"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="1603"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="1708"/>
            <end position="1804"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="1808"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="1904"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="1994"/>
            <end position="2088"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="2089"/>
            <end position="2187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="582"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="756"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1188"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1210"/>
            <end position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT84147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2316" mass="254528" checksum="957EA49D67544CF0" modified="2019-05-08" version="1">MTTHGTRMTRMLVLVVDGVAGGPPKVPRRAQYDKLMRGRGQEVALLCEAQAHPLPMFRPSPNTEGFLVLVVSCDRMRHLHTTQRLVLSNLTSAEPVSSEAPKVSEYAKSPTFLRASGSSFTLLCPAQGFPVPQFSERFDVSETGVGEPSTLTCKAQAHPTPEYSPISKGLLTAASGVRLLQGRLQRGTIQHHAKFCSLLEPFSSQAPKASGARGDILTKERRSAFAITCKVQAFPLPEFRNQSIYNQISRFDSLNATPWHSLALDPLSSESPKVSGEQGVAMVRQEGAGFSMLCPAQGFPVPSFRSVCALVCPMRTEPYSSEAPKVSGAHGEIIIRRAKTGFALPCRAQGHPVPEFRSELSPFSSEAPKVAEGEKFDNLMRASGSSFALPCKGQGFPVPEFRYVVEPKRYHEAAEAKATVPLCFVHAPPSPSPFRLHRRYILLFEAPKVSEVERIVNLMRASGSSFALPCKGQGFPVPEFSGAPKTEGEKIDTFKRARGSSFALTCKAQGFPVPEFRAPCEERKNVIINLTFSGSEPISSGSPKVAEGEKIETLTRGVGSSFALLCKAQGFPIPKFRSVLPSVRRGPKSRSRASPPGWPRRHGVTSSSSRRTLLSPFPARLRASPCRNLEPFSSESPKLAGSRSDTFYRRRGSSFAIPCRVQGFPVPEFRAPKYVQIPKLKKRQKLIKLCAPSEPFSSESPKVAEGARGDIYIRHQGSSFALTCKVQGFPVPEYRWVCREGDVKHYSIVGTATHPKTKSSSRLLQHSGLRHPSPTALSSEAPRVAPGGRGFIMVQRAGAGFGLTCPVQAFPLPEFRWFKVSEGGRKAAVELGDRVKQVGGTLIIREAKVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAQVEPKVQTVEFGRPATFTCTYRGNPVKSVTWLKDGIPLNHKEAVLRIDTVGREDKGMYQCFVRNDQESAQGTAELKLGGRFEPPQLIYTFQTNTLQPGPAVFLKCVAAGNPTPEITWELDGTRLANSERMQVGQYVTVNGEVVSHLNISAVHTNDGGLYACVASSTVGSVRHAARLNVYGLPYIRPMDKAAVVAGENMVVHCPVAGYPIDSIVWEKNGRMLPINRRQKTFPNGTLIVEAVQRSTDQGRYTCVARNSQAYTARGDLDVQVMEPPQIHPLVVAGTPVIGKELLIPCYVVGGDSPLDMVWQKDGQPISPARLDSNPPDPWHSPGDRRERSQTLEESCELLSSARNESELGGGDELNMFSANIGLDPHLAVHQRGDRYLVLRFSALCPHHSGNYTCEASNMAGTVGYTVPLDVLVPPRWIVEPADKAFALGSDARLECKADGFPRPTLGWKKAAGHTPGDYRDLDVNNPNIKVTDDGTLHISSIQKSHEGYYLCEANNGIGAGLSTVIYVRVQAPPQFKIQYRNQTARHGDDAVLECEAGGETPIGILWSKDKHSVDQAAEPRYTIREEMRGGSVHSSLSIKTTDRTDSAVYTCVATNAFGSADTNINLIIQERPEQPSSLKVLDKSGRSVELSWTSPYDGNSPITRYIVEYKLSRRNWENDGERMMVPGNQNMAAVLDLRPATTYHLRIVARNEIGDSDPSDIVTIITAEEAPSGAPRDLKVEAVDQNSLRVKWKPPLREEWNGDIQGYQVGYRLASSNTSYVYETVEFSKEVGKEHQLTIKKLQVYTEYAVVVSAFNKIGQGPTTEEIRSYTAEGTPQQPPHDVTCTTLTSQTIRVSWASPPLETVQGVIKGYKVIYGPSDKWYDEERKDTKITSSTETHLHGLQKYTNYSLQVLAFTSGGEGVRSQPIHCQTDQDVPDAPTSVKALVMSADSILVSWLPPDRPNGIITQYTVYFKEEGKSDSEAEQEKLLSSQLNYEANGLKQRDEYVFWVTASTTIGEGEKSESVHLKLSSKVPAKIASFDDEYVATYKEDVKLHCQAVGLPTPDIRWTIRGEPFTPNDRMRLLTEGSLLIREVSRDDAGEYTCHVENPYGQDTVTHTLLIQAPPHPPEIQLQSTTTNSIEVKLKPSVIDDTTPIHGYTVYYKPEFSTWESVQVPASTRSYLLEGLWCGSRYQIYASAYNKIGTGESSEILNTRTKGKKPEIPEVHRFVEVSSVSINLHLKAWQDGGCPMNYFVVEYKPRHQTEWIMADNQVSPTGNYGIMELTPATWYNLRISAHNNAGSSVAEYEVATLTLTGGTIAPAREVPAFGAGDLPIYLNLNLIVPVVSAVVVIVLAIVIICYLRGRNTPIKATLPPTVSDSRVTWLPDWWPKWLDLNVLVPVIATIVVIIVGIVVICVAVTRRKNGIENLRLRVEFTSTSPFTVTMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6L1</accession>
    <name>A0A423U6L1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6L1"/>
    <dbReference type="OrthoDB" id="6346354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="177" mass="19549" checksum="FEFA40A456B98F20" modified="2019-05-08" version="1">MSRVWPLLLRSTVILALWVALAILSVRTAQSLVMKSHLPIVFLAVCGIFYIILNIVCFTQLILCKSGIINRLFLILLLLTMTVLMYPLCLQVWRAFMAAIEKDPRIRKQKILKARYANWVASKPSAKQLPDVDSPHTFGSCVPSRLAPASPSGASSQQDASVPDNDSPALGNQHQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6U5</accession>
    <name>A0A423U6U5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000547">
        <property type="protein sequence ID" value="ROT84412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6U5"/>
    <dbReference type="OrthoDB" id="10056806at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="260" mass="27938" checksum="62CB5BA13DD75E71" modified="2019-05-08" version="1">MSGWMHSSGIGPGGISSIGKGHGVPEPKPFYLAQDNSSIHTSSVVKACSLLKLNLSDKLGYMDQVFPICDRNLLISDMFLQSISPTPNLASMSSKSRDMAWFLTAMLLLVAGGCVLTQAHEIEREDVNNGDGFEDAANLRQLHECVKTPPKCSNEGGFCLNLQLSCAGKMNASLCNNDNCGCCLKHECINTPKICSSQNGVCINLMDDCAGQTDESLCRNKNCKCCMKHECSNTPKMCSNEGGTCINLMDDCAGKADECL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7E8</accession>
    <name>A0A423U7E8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000517">
        <property type="protein sequence ID" value="ROT84637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7E8"/>
    <dbReference type="OrthoDB" id="6682367at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1200">
        <property type="entry name" value="Alpha-tocopherol transfer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174">
        <property type="entry name" value="ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10174:SF224">
        <property type="entry name" value="RETINOL-BINDING PROTEIN PINTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="133"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="393" mass="45338" checksum="7159A7260862BFA4" modified="2019-05-08" version="1">MQPPPPPSTPPPPHHANSMHYAGCCMHETGTGHHTDSMGGEYVCTLSEELIQRAKDELGEDPARRAQDIEHIRDWLKHQPHIRARTDDWTILRFLRGCKFSLEKTKEKLDMFYTCKSLCPEWYTNRDPQDKKMREILEMGVMLPLPGYDHQGRKVVFGRWGIYDPNKVSMDEVMKLGSLIFDVLLDEDEQATITGVVMAGDCTGLTLAHAMAYTPAMAKKSMVLWQDGYPMRPKGLNYIHTPAAFDTVFSIFKSFMKEKMKKREIPKEILPVEYGGTNGTIEEIKNFYWSIFFQEFARPLLPLSSRERPVLRRTDYWIQRVDLAPGGREVRRGRVEAPREGQDVRRPLRDRGLLQEAQRGLKDGLARSVSGMEVFWRLGSSRDAWREEDFAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7T5</accession>
    <name>A0A423U7T5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein bride of sevenless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000501">
        <property type="protein sequence ID" value="ROT84773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7T5"/>
    <dbReference type="STRING" id="6689.A0A423U7T5"/>
    <dbReference type="OrthoDB" id="6417989at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005118">
        <property type="term" value="F:sevenless binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002956">
        <property type="entry name" value="Bride_of_7less"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01223">
        <property type="entry name" value="BRIDEOF7LESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019483136" evidence="7">
        <location>
            <begin position="25"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="648"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="8">
        <location>
            <begin position="435"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="764" mass="82516" checksum="3D7092D78C623DEB" modified="2019-05-08" version="1">MKVPGVGVFVLLATAVGGPGGVWALWGGEEGMCGRHRSFPDLQSDVYITGLLGIHGGARCGLVDPAGVQLMEAARWSAHKLNENNFVPGVTLGVNLFDTCGGPDAAVRAGVSAMVEGGFLDDPECDSGKHVGVLHTHPDNDNLVNFLEDVGVPSVSVGSPDLSPQLEALMPLLQRINWTSIAVAAPSVTMLREFGNLAANARICVSAEAILPYNSDQASYREVLETLGSGKTRGVVLLGPQDKLHATLTTAAAYNLTDFDWILAPTGPIQEHFFQGLNKVGTGLLAVRRASQSVPKFGQHFLDISATDSTLYPSSLPDDYVEEPAVFQVVEAMFKMGAGVRRAVLDQCGGSGWCSNASVVFTDPHTDGLDVIEALSIKTQRPRYQVGYYSADVLDLDRSVLEGPNKPRPHPCRSCRCLNVGFAFLIDLRWRTNAWVTICATTAIIGILLAVAIFVFVASRSCRGRAPEGSQAFTLLLLVSCVLLYSAILPYSFEASSLTCALRPFVTSLTYAIVYSIMLARSLMLATADSEGLVGHVSGLVQTALLFFMVSVQAGLGVQQWVMNPPHTAFLQPPSAKGILYTCSGDRLYFIVSQSYVMFLLLLQLLVSPFIVRSRRNYHEGLLYFLATLLMAGVWVGWATLFMLLPPVWSDACICLGLAATPTALLLTVFIPKTYLMVRASARESACATPIRPISRPQSVHDLPRVSSLALYDSISHLPEMSYAQVHAPSHAYTPDPTAHLGHKESPYEAYSHYQPSPHKVTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSF7</accession>
    <name>A0A3R7LSF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative rho GTPase-activating protein 12 isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020437</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004004">
        <property type="protein sequence ID" value="ROT61753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSF7"/>
    <dbReference type="STRING" id="6689.A0A3R7LSF7"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="10"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="626"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="80"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="390"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="501"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="669"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="760"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="567"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="771"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="906" mass="101280" checksum="7B1A152BE05B382B" modified="2019-04-10" version="1">MTEGSMKGVENEEFVEAMHDYSYQWEDRTLSMTKGEIFMLIKRASPDWWQVIRHGEQRSFFAPKQYLQLTTVSYEQMKQVSRQGRLQQKSKQEESSGQSHGMPQISNDNIPSPPFTEIPSSTTPNASQSYMTKIEPSRVTKERSDPYPSRPGGLSSFKSESPIVPPKGLPHRSGSNEFPSPTAPSRGFSQGGHESSSSHTSRSSLNDSSRCSMESLTQLHARKQAIKAASHDELMSGERSRSVLDVSQPKAASSEELDGRYCGRDFFFKSNQLSYRHRSNSVDFRLFQKDLAFSEMKQGSLDKSRKPRISKDPGNRRRSWAVEERLPENFRPFKKAETQDTAIILDVPPKLPPKQRKHKHDLFGSSSENLGKLEGPIDIKLQEVKKAKPALPLTGPNVKRLGQDYDRSLKGPDTSTLSENQRKASLRRQDGMDAKDPPVALPRKFIPPQVSSTESKTEEQGSKQNLKAGAVMPSVSESPAKDSINNKVKSEFNDLIHTREQSAQEVRSLAVYPSDLREGNTFRPDSAQKPGRVDSFRKAREAPRSPSRAPGTPEMNRKVFTPGTPDSIRKSYSLERGSPKLDLGKEEEKENEGLRIPQREVHTPDSARGVKVAMQMPPSPRTPPQRIVFDDWGEYFDEITKRPYYYNSRTREKRWKPPRKGIHSVAIPEVPPHARQENRGGSLGRGQTRSPPIDYPASPKLSQMPRSYATLPESGSGGYLGFGHSSTLTHTSSSNIHIHHQVLATSHTLPLFSQSSRNILPPLVPPSSAKPTLPNTPTTPTTPDVPDDQNVALLDTLYKMSPPRGWSKKFDNFTQRVYFCNQVTGERIQELGHSSDWGMLDIGTVWQCTLSCVEEAVLVPGGMVCAARITESLTPQQPCFSLSLHTSHMPVNARCCIRVSGILHPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTZ0</accession>
    <name>A0A3R7LTZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003542">
        <property type="protein sequence ID" value="ROT62822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTZ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="543" mass="58571" checksum="1E53AE7CD387C11E" modified="2019-04-10" version="1" fragment="single">LPVFFSPVHHFRSPTTLFLFISSLSPCQSHSPVPLPLSSPPIPLPSALSASPLLLLPPLPLFLSYPSPFFLPLPSLSLLSSLPCPSSSPSPPSSPSPISIPYPSLSFSLTLTLCISCPSSSPSLLPLRLPSPYSSPFPSLPRPPSLPSSYPSLLPLPSPLPLPFPPSPRPPSLPFRLSRQHLKGQGRNITLESIPLNDRARVPFRASPPSLPLPHSPSIPLFLSPHSPSLPLFLSPHSPSLPSLLLPSFPFPPLSPLPHSPSLPLPLPSFPLPPSLPLPSFPFPPSFPLPHSPHSPSSFPLIPFPHPLPLFLSLIPLPPSLPLPSFPFPPSLPPLIPLPSLPSSPLIPFLPSLPLPSFPFPPSFPLPHSPPSPLPLPSFPFPPSLPLPSFPFIPLLPLFLSSHSPSPQSPRLPSLHPLLSRYAFSLHLFVFPHFLSPSPLFQSFNLRLFLPSASPLGTSPLSLYPSLFYLSSSLSSLSFLPHPHLFLFSPLPSPLFPPHPPHPSPSFPFPTLPVPFLPLPFPFPPLPVPFLSLPSPSLRFSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTZ8</accession>
    <name>A0A3R7LTZ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003536">
        <property type="protein sequence ID" value="ROT62843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTZ8"/>
    <dbReference type="STRING" id="6689.A0A3R7LTZ8"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="230" mass="24455" checksum="162A559556D60CBB" modified="2019-04-10" version="1">MTPPDGPFTVFAPTNDAFAKLPPGTVDSLLQDVPALQKVLLRHVVPSTLYSRALLGNSFSTASQDQVVWGKERRTRGPPLVSLAAVPRPVAAGAASESTEDHLRDSEEQIREGVYGESSEAECGQESRSPAPLAADSPSRRRPGTGAPTEPRAKALGQDGPGARLATCLVEPEGKGVEARPFKCLSQGRPVVARSGVRAGPPRARRATTWRSAEWDLCLAAILKPLKYMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUC9</accession>
    <name>A0A3R7LUC9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003473">
        <property type="protein sequence ID" value="ROT63218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUC9"/>
    <dbReference type="STRING" id="6689.A0A3R7LUC9"/>
    <dbReference type="OrthoDB" id="6287725at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="43977" checksum="2F0425BA5779D6AF" modified="2019-04-10" version="1">MGPSERSAEPLIHHAQPAAAPHTTIAPKLTLDTIAARRPASPTSMSDHSESSDGDLGDMTPCNASPSIAAMLFRPIRQPNDLEDAWRATCCLSWQLMPPFHIPQDLVSMVLSRRSSSRILVRVYQNCVQTNSTLTCVAVCTSCTSSSLFFYDTYAKFIVAMLHAARNSQASDHSVELSALQGKLMAAAEQIDATPPTTPTRSSHSLPPERELPEFRFTFQYVFDSGYLNIPFNCLLFISRRGGECESVGGEESEGGSACESSISRAEGGSPVSSSSLGSQSLELPVAPPGSRPEAERQLLQLVADQRWVDALQFVRQHRALWLREVSAHTNEDITIILNTYCAYHADKKPGMIAVCGTETELLETSSRLTEANMSALSALRAIEQTPKQSRDSLESVIRKTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXC0</accession>
    <name>A0A3R7LXC0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prophenoloxide activating enzyme III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020421</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004000">
        <property type="protein sequence ID" value="ROT61763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXC0"/>
    <dbReference type="STRING" id="6689.A0A3R7LXC0"/>
    <dbReference type="OrthoDB" id="547031at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000028">
        <property type="entry name" value="Serine protease easter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S1" evidence="5">
        <location>
            <begin position="56"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="26738" checksum="FBF540ADDE27191B" modified="2019-04-10" version="1" fragment="single">AICSFLNSEPLVCCPSQSLPVTAVNTPPTRPPPVVQTPPPSRANVQCGSRGIADKIIDGEDAPLGAWPWMVVLRGSINGRRSWFCGGVLVSERYVLTAAHCFKERLGLVLEIARIGEHTLSINPDCSKGRCAPPPQDIPVERIIRHPQYGSPCTECNDIALLRLSRPAVLHPRFVAPVCLPTNPVQDMGFSEQEFQGKAAWAAGWGSTARDFSVSRRPDVLQQVQLPIQELNYCDRLRGLSQTPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZL1</accession>
    <name>A0A3R7LZL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002801">
        <property type="protein sequence ID" value="ROT67559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZL1"/>
    <dbReference type="STRING" id="6689.A0A3R7LZL1"/>
    <dbReference type="OrthoDB" id="10061772at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41298" checksum="BEF297321FFACEAF" modified="2019-04-10" version="1" fragment="single">RSMMDAPTNTIFTFIDRELTAQANDKDVTEVALAELYAYVQSLPDSAKKRRLIKQFNHASGSGTPQLNQSFLKRQEARGKRLGDSIKTKIQPVSPSLPSPCIFSFESSYDNLEGTREADQSSMDNTMEAFSQSNLIFPLVFMMKQKRMLPPGTACLHLPSCCKAGGSLSISQAMLQASIPQFSSATHQTLADSTNLSINTTDSEMNDPEYNKGKAITNRKKRDSEGSCENEGETKLKRWGSSTLRRTLSSASSTGSLFGSFFRLSTSSLAQLASRLSSTTSLTNPEVQEEEKSDESETEEDGEMNESLSSVFKDYLLSRSILTDNPVDLSTDCLEKGIEEEDKVEIQEIPQTTDSNEENSDDNLVDSAYGESQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M080</accession>
    <name>A0A3R7M080_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative zinc transporter ZIP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012439</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002569">
        <property type="protein sequence ID" value="ROT69355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M080"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF203">
        <property type="entry name" value="FI18611P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="132"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="52418" checksum="666C302A20F90A8E" modified="2019-04-10" version="1">MELLTTKIIALTLMGVLSLFFGLLPLRLKKYIHHASKKRERIVSCLLCFGGGVLLATVFTHMLPETRENFANAFASNVLTVGADYPLAELVICAGFFLVYFVEEFVHKIFFRRDHHHGRKMTKLAAAIEGENGHSHHHHHHHHHPHSHHHHHAHSHAHTNGTSPTDVQPVKPDSLQNGKKTQDPGRCAVYSITGAVDSSRGVGAGGGGGDVSSKTRWAESGVDNPVFAGDIDAVTWNPELKDSITNGTQVVPVTTSSSSAVPEAVAHGGHGHGHSHLSIGKLGSKGLASNLRSLLVILALSFHSVFEGLAVGLQEREVDVWYLFGAICAHKLVIAFCMGLELLVAGTVVGLMVVYMVVFALVSPLGIAIGIIVTENITSNDGGHLVAVTILQGLAGGTILYVTFFEVLERERNHGGGRLMKLLFIVLGFGAMAAVEAGFGLCCRSASAGRSTAGERGGRRSPPAVAVIQGLAEESQNGKLGSEQRVASDLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2J1</accession>
    <name>A0A3R7M2J1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002485">
        <property type="protein sequence ID" value="ROT70004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2J1"/>
    <dbReference type="OrthoDB" id="6381662at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="283" mass="31105" checksum="313C0EA22B63D9A7" modified="2019-04-10" version="1">MASGTGRAALVRVEAPPSARRGPDRPLHRARVLFSRRRPGHRVPSSLGSFGSSEFPSPIRPRLAWRKTLFDPYEHRISRIRTRGLSGLVSERAAPGPPVSCLPAQEKEALGRRGEAEALGYPRGGLLSLPQPSGLQQGKAMESSYEMKVLLWSVTCGVALILGLMVAITYLLLRQNKLLKARRSASSGPPPRITRAKSRRGPSKDEVSYLTPTGLPPPVSSIGRGDQPPRPKGVHLPMRHPIEDSPASSLDNHIYEDADYMYEPIQRVSRVLRRARGGRQTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M301</accession>
    <name>A0A3R7M301_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003021">
        <property type="protein sequence ID" value="ROT65871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M301"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="48241" checksum="B1077327DCBFA8A4" modified="2019-04-10" version="1">MPLDLPRLQGHGASGYIYPLGTRYGLCFARRKGPFACLGHVTDSALRGGRVLSPAWDTLRTLLCEEEGSSRLLGTRYGLCFACLGHVTDSALRGGKGPFACLGHVTDSALRGGRVLSPALGHVTDSALRGGRVLSPAWDTLRTLLCERKRLLTRYGLCFARRKGPFACLGHVTDSALRGGRVLSPAWDTLRTLLCEEEGSFRCLGHVTDSALRGGRVLFAAWDTFTDSALRGGRVLSPAWDTLLAFARRKGPFACLGHVTDSALRGGRALSPAWDTLRTLLCEEEGSCAHVTDSALRGGRALSPAWDTLRTLLLRGGRTRYGLCFARRKGPLACLGHVTDSAFARRKGLSPAWDTLRTLLCEEEGSSRLLGVTTLPHVTDSALRGGRVLSPAWDTRLCFARRKGPFACLGHVTDSALRGGRVLSPAWDTLRTLLCVPAFVTEPCCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M776</accession>
    <name>A0A3R7M776_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_012863</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT69008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M776"/>
    <dbReference type="SMR" id="A0A3R7M776"/>
    <dbReference type="STRING" id="6689.A0A3R7M776"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000173">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="15">
        <location>
            <begin position="11"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="16">
        <location>
            <begin position="83"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT69008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12484" checksum="BF6E47AF7A70BA73" modified="2019-04-10" version="1">MSGRGKGGKVKGKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAEDPYHPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9E3</accession>
    <name>A0A3R7M9E3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Bone morphogenetic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_011051</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002401">
        <property type="protein sequence ID" value="ROT70662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9E3"/>
    <dbReference type="STRING" id="6689.A0A3R7M9E3"/>
    <dbReference type="OrthoDB" id="431034at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032927">
        <property type="term" value="P:positive regulation of activin receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030513">
        <property type="term" value="P:positive regulation of BMP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000013">
        <property type="entry name" value="Membrane frizzled-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000004">
        <property type="entry name" value="Metalloendopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000052">
        <property type="entry name" value="Metalloendopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000005">
        <property type="entry name" value="Procollagen C-endopeptidase enhancer 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015446">
        <property type="entry name" value="BMP_1/tolloid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF43">
        <property type="entry name" value="TOLLOID-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001199">
        <property type="entry name" value="BMP_1/tolloid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 14" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="11" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="17">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="15">
        <location>
            <begin position="60"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="15">
        <location>
            <begin position="177"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="16">
        <location>
            <begin position="289"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="15">
        <location>
            <begin position="332"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="16">
        <location>
            <begin position="446"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="15">
        <location>
            <begin position="490"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="15">
        <location>
            <begin position="603"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT70662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="743" mass="82995" checksum="74A8FD6557B42E8E" modified="2019-04-10" version="1">MAAASLGRSSLRSDAAATYLDTIRPRPEPGQESLPEIGQRIRLSEGDIAQTNLLYKCSKCGRTYQENAATFSSPSYVNSAPPPGGEKCEWRITATHGERIVLNVTHMDIFKSDGCKTDFLEIRDGYWHKSPLLGRFCGGLRFPETIVSTGSRMLVSYVTSVNQNGHKGFTSSYEAVCGGELSMEQGHLESPNYPDDYRSNKECIWKITVPIGYQVALRFHSFEIENHDDCVYDYLDIRDGHEENSTLIGVFCGYKKPEDIKSSTNKMRIKFVTDGSVQKAGFSATFMKEYDECASLDHGCEHICINQLGGYECQCKIGYELHSDGKRCEDACGGQIDQANGTITSPSFPDLYPVNKNCIWEIIAPPQYRITLNFTHFDLEGNNQDCEYDSVDIRSKLGTSEMRKHGVFCGQRLPLVITSEGNSLRIEFNSDNSVQKSGFAAVFFTDKDECATDNGGCQHICKNTIGSYVCSCLNGFTLHENRHDCKEGGCKHEITAPVGEIFSPNYPDYYPSRKDCVWQFTTTPGHRIKLVFDEFEMEPHQECTYDHIALYDGTTSETGFLGRYCGAKVPHPIVAFNNQMFMVFKSDSSVQRRGFRARHTTVCGGGLKATSTVKHMYSHAKYGDQNYDNKEDCDWIIQAAQGESVHLTFLTFELEDEHDCGYDYVEVFSGYSDSGPSYGKFCGNTIPQEIVSINDALLVRFRTDDTINTKGFSAAYVAIGDNTLAENSTGDNNGFSYSFSRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MB59</accession>
    <name>A0A3R7MB59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001453">
        <property type="protein sequence ID" value="ROT77975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MB59"/>
    <dbReference type="OrthoDB" id="10382408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="11936" checksum="EF9563ACFEE9E604" modified="2019-04-10" version="1">MSHLPNSSDRNCSSQNASPLAPRSVLVERVSAPSVPEQGPRAMEPSHNGFVNNLSARTSRVLPEAHVYTPTACDSTALDLDLGSNFVWADDDLVNEDFDALLDAALHLPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MB74</accession>
    <name>A0A3R7MB74_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MAPK kinase 1 interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LAMTOR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001448">
        <property type="protein sequence ID" value="ROT78018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MB74"/>
    <dbReference type="STRING" id="6689.A0A3R7MB74"/>
    <dbReference type="OrthoDB" id="343907at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000003">
        <property type="entry name" value="ragulator complex protein LAMTOR3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015019">
        <property type="entry name" value="LAMTOR3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13378:SF1">
        <property type="entry name" value="RAGULATOR COMPLEX PROTEIN LAMTOR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13378">
        <property type="entry name" value="REGULATOR COMPLEX PROTEIN LAMTOR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08923">
        <property type="entry name" value="MAPKK1_Int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01278">
        <property type="entry name" value="MAPKK1_Int"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="124" mass="13772" checksum="CECC95DB7BBA8821" modified="2019-04-10" version="1">MVEDMRKFLFELLHRTDNLLGIVITDRDGVQLLKVFKDDAPDLGMRPAYLSTFGMATDQAGKLGMGKNNKMVCIYGNYQVVHFNKLPLVVTVIGTSTANTGLLMDLENEFSHIVSQLTHVVDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD67</accession>
    <name>A0A3R7MD67_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen debranching enzyme</fullName>
            <ecNumber evidence="5">2.4.1.25</ecNumber>
            <ecNumber evidence="6">3.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Glycogen debrancher</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C7M84_008329</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin.</text>
            <dbReference type="EC" id="3.2.1.33"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the glycogen debranching enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="5"/>
    <dbReference type="EC" id="3.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002049">
        <property type="protein sequence ID" value="ROT73239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD67"/>
    <dbReference type="STRING" id="6689.A0A3R7MD67"/>
    <dbReference type="OrthoDB" id="10248904at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000206">
        <property type="entry name" value="Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000039">
        <property type="entry name" value="Glycogen debranching enzyme Gdb1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032788">
        <property type="entry name" value="AGL_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006421">
        <property type="entry name" value="Glycogen_debranch_met"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01531">
        <property type="entry name" value="glyc_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14702">
        <property type="entry name" value="hGDE_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="18">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme central" evidence="19">
        <location>
            <begin position="337"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme C-terminal" evidence="17">
        <location>
            <begin position="718"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ROT73239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1189" mass="134800" checksum="524C3B0271B2A314" modified="2019-04-10" version="1" fragment="single">PEARDEEDRIVRCCAEFRRHVENLNQQRTSEIQAHLIQAVECVLGTIRYQRLQPDGPMIAEVSRDYPLVPPYFTHYGEDASLEEEEALMFGDKGCYLMAHNGWVMGDDPLNNFARSDCYVYLRRELVAWGDSVKLRYGDKPEDSPYLWDHMKRYCEYTARIFHGIRLDNCHSTPIHVAEYMLDAARKVRPDLYVIAELFTNSDITDNVFVNRLGINSLIREAMSAPNSHEEGRLVYRYGGEPVGAFLLPPVRPMVPCIAHAIFLDLTHDNRSPAEVRTAWDMLPSTALVSMACCASGSTRGYDELVPHHIHVVDETRVYQAWTDAEPTRGECNESSGIVRCKRLLNKLHFELGANGYNQVFVDQVTEHVVTVTRHNPVTHQSVVLVAYTSFRPPAEARESHIRPLKVQGHLEEIIFEMQVKGKTSGEDDKSYPGFFNNDSEFINGLNSIIAEVKENIRPSESSLVRLTSPEDADETECQYTSEFAPGSVIAFRLSLLPRAQTAVNKIRGVLSEFGYKSRISEVTTHNVELMDIVNSLSLSDLNRVLYRCDEEEKDEGHGGGTYAIPNYGSLPYCGLQGVISVLSEIRVHNDLGHPLCCNLRDGDWMPEYIVTRLKHEPATQRLAKWFEDIFNWLKEVPRYLIPAYFDSIVTSVYLTLINRAWSLMGEFISQGSDFAKALSLCSVQFCGIVKSAVMPPLSPNLSSPQPPSFTDGSGSTKQMSVTIAAGLPHFSVGYMRNWGRDTFIALPGNLLITGRYDEARWIILAFASTMRHGLIPNLLDGGSKARFNCRDSVWWWLQSIQRYVAIVPDGNRIFRDKVSRLFPSDDSPPQEPGRHDQLLEDVIQETLQRHFQGVKFRERNAGYQIDREMCDEGFNNEIGVSMETGFVYGGTVHNCGTWMDKMGSSELAGIKGKPATPRDGSAVEIVGLCKSALRFLGQMYREDKFKYNSVERYDDTGNVTKWTYEFWEKKIQENFEKYYWIDENPIPDREPKPELINRRGIYKDSYDASQFWADYQLRCNFPVAVAVAPEMFTPKHAWIALKNAEKILLGPLGIKTLDPSDWAYNGDYDNSNDSADPKIARGYNYHQGPEWVWPVGWLLRAQLAIAPKVGGFEELGRTMGHVKSLLAPHLTHVLSDAWRSLPELTNTNGAHCKDSNPAQAWSTGCVLEVLWEMDRIERGLRRSSMTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIJ6</accession>
    <name>A0A3R7MIJ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U4/U6 small nuclear ribonucleoprotein Prp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_003879</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001519">
        <property type="protein sequence ID" value="ROT77471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIJ6"/>
    <dbReference type="STRING" id="6689.A0A3R7MIJ6"/>
    <dbReference type="OrthoDB" id="10264544at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="8">
        <location>
            <begin position="298"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="7">
        <location>
            <begin position="534"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="323"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT77471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="665" mass="74833" checksum="CE5C52C3C5EE47B1" modified="2019-04-10" version="1">MSLSKREYEDYKAAVEKMVYKYVTRDRSSIVSAIAHAVDSGCDKRKVEDKLMGYVDKSLAYKLAEKAFIVLEDIGAKVKSSSSRKRTHKDENDREKDSKRARVKEEKEPPPESKQPPPPPATAPNNTVSPGQIQAQQIKDIMAKAQAVIEERKKAMANLHPVEPKPATNGAAVPLINQATPAVLAAVGSSDVSSRIAELQARIQAQLGNVSAVGIGSALAAGVGGAGGAPPPAKPQGEQSKPTPLILDAEGRTVDMSGKEVHLTQRIPTLKANIRAKKREEFKQQLQEKPVEDTVESTFFDNRVSIRPSMKAKRMFKFHDQGRFIQLAQRERAKARLEKLQNEISQVAKKTGISSAAKLAQLEQRDIKSTTDGCPEVEWWDAVILKGNRYPEENETIAINEDYITRLIEHPLEMKCPSDPSKPVTLQVFLTKQERKKLRRMNRREAWKEKQEKIRLGLEPPPEPKVRMANLMRVLGTEAVLDPTKMEKHVREQMAKRLKAHQDANAARKLTPDQRRDKKIRKLKEDTTTGVHVSVYKVTDFSNGSHKFKVETNAKQLFLTGTVVLFKDINVVVVEGGPKQQKKYKKLMMERIKWAEESRSKDAELESKCQLIWEGSVPERSFGEMQFKACPTESFARDHFKKHGVEQYWDLAYGKKILEEADEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ59</accession>
    <name>A0A3R7MJ59_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Armadillo repeat-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003495">
        <property type="protein sequence ID" value="ROT63090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ59"/>
    <dbReference type="STRING" id="6689.A0A3R7MJ59"/>
    <dbReference type="OrthoDB" id="247006at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044782">
        <property type="term" value="P:cilium organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038905">
        <property type="entry name" value="ARMC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21356">
        <property type="entry name" value="ARMADILLO REPEAT CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21356:SF1">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="904" mass="99804" checksum="0BC957116E8AC6EA" modified="2019-04-10" version="1">MTSCSSRRRPVPLASPQGPERGSAMLSQAVDRRRDIVGQDILSPFYAPPDRKTSAQIIREARNAINLGDAGMGVQRMGVRTVQTKRPFTPRERERTLFSSSAGTTRGERPPSSFTISCLRWCPLEGFKGTNFELCPSATCLRKRRTTMTGARHLGAPPCQCLSAVPLVYDEQLTGALATSSESITNTPLFQQLLNNADLEQTDDSKAPPPEPIVKSHAPKPTPRLRKTDSAQGKKSISKRAGVDRDWRHAVEGRSQNPQTEAQDEDKGLTSQTPTNREVAVDQTVYYEEKINPILDEISRAVGCAVGEDVLAELVGKLYGALEAGGLLGRHFRYRSQVLRAVFRLVDREHGALLANIARVMLAVSPRGKGLGKIKFVGVFRSQVSGSNLTSVCKLVFKVTRHDANDALFLEGNLLDLLLEAVACVPPLEQPEACVYGYGALKFLTMNSQLVTRLLNRGVLELLVLHMKLIVNHQQESGSVPEQTHYALVQLTGTLRHVSSCERTFPLLLVTGAVPQVCNLLQHFSHDADVTANVVRILSIISTHEECCAAAAAHPGTLPATVNALPRHASSPAIVVRLAYALGNMMANSDDARWQLFSEDGFTETLLELLTEYLRRDRHHQAEEMADPLTSASGAPEDVMVKLIRVLANVSVHARVGPVLARSRTCLSLLISVLRHKAVDESEELVLSALATLNNLTFYTRDQPVSALHTQLAECLCDMLPMDHVEGLVETIRVFGNLTHFREIRDIVTKRAVLEILIEMLDCDSRELVYVCAGVLVNLMSDASRRSIFQEENGVLRMIDVLQYFGYGDWQLCSLACQVLWNFCASAADVQSTLGDKETEKLVFVLEEFLDDDSYFNNPEVFGECDPETKDVVYQLWEDFAQVATKLLDRIEENTSSLPIVSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML49</accession>
    <name>A0A3R7ML49_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_008019</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000202">
        <property type="protein sequence ID" value="ROT85724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML49"/>
    <dbReference type="STRING" id="6689.A0A3R7ML49"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005221">
        <property type="term" value="F:intracellularly cyclic nucleotide-activated monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF7">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED ION CHANNEL-LIKE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="263"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="489" mass="55714" checksum="01B3C3C8054802FE" modified="2019-04-10" version="1">MRRVVDQDDLDDGDFDYLGGPRRPSGESPRPRSPSSPAALRATGRNSRRVSLIPGEALEQAHASLALAALTQVHEQAQQNAQLHEQSHQNKAPREKPPVVKSKTTDEGGGGGLPGAPDGGAVTTDSSPISERDKPPRLDNSSKLSRSRSEQEWTNLRAAMAWYSRLRRIRRMKSNQRWLKLRTTVQLSGALSSSMNRTKPPLKREDSFIKRFSTRQIAELQDTVDQTDEEDVSKNSTGSPKIRKKKKQRQPRTVINPYGNVFFYWLCSLTICVLYNLWTPIVRQAFPELQRKPQPMWYLLDGLTDIVFVVDIFVQFRTGYLEQGLIVLTHISPPTPNVSIQNREIDLTSCPFLQIGPQPLIRFPRFIKVYRVYNYYYMVESRTLYPNMWRVVNLIHILLLLAHWFGCFYYMLSEAEQFVGEWTYPYDSSESGAAWVPLRFYVGACGGSVRGSEGPDFQTLSRMYLGSVYWSTLTLTTIGDLPTPETNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSU1</accession>
    <name>A0A3R7MSU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative wiskott-Aldrich syndrome protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_021573</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000454">
        <property type="protein sequence ID" value="ROT85032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSU1"/>
    <dbReference type="STRING" id="6689.A0A3R7MSU1"/>
    <dbReference type="OrthoDB" id="8963340at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00132">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01205">
        <property type="entry name" value="EVH1_WASP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000130">
        <property type="entry name" value="neural Wiskott-Aldrich syndrome protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011026">
        <property type="entry name" value="WAS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033927">
        <property type="entry name" value="WASPfam_EVH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11202:SF36">
        <property type="entry name" value="ACTIN NUCLEATION-PROMOTING FACTOR WASL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11202">
        <property type="entry name" value="SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00461">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47912">
        <property type="entry name" value="Wiscott-Aldrich syndrome protein, WASP, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="7">
        <location>
            <begin position="27"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="6">
        <location>
            <begin position="203"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="137"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="328" mass="37342" checksum="128F305E7DA54CEA" modified="2019-04-10" version="1">MGTRKPPVVNKPSTLLSREENEIMIRMLGPRCQTLSTAVVQVFGTDGPHHNAWRKRYCGVATFTKDNARKSYYIQVYDTVAGVRLYEQELYNQFTYSAMMPFFHQFEAEDQMIGLNFADEGEANAFSRAINERLAVKQRRREERRRQSDQQQRQSLHPQPTIPSQPQQTPVHAPPALPPKDDNKKRSGKKANKNKNKISKEQIGMPTDFKHITHVGFDPDKGFSQFNMDEKLQGFFNMVGVSQQHLSDTRTREFIYDFIERHGGVEKAMQETQRYSTSPNPPGAPEVSHMPPPPANTLSPPTPPPSIPSRNSFNEEKAEQVVADGKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MTV8</accession>
    <name>A0A3R7MTV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012138</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002540">
        <property type="protein sequence ID" value="ROT69634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MTV8"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="42655" checksum="3282A0696A9A05D8" modified="2019-04-10" version="1">MALTKSLLIRLSLAVRHLLPKWHSPLNSLALYGHVLLVLLCAAFLAVMAGVGALDDEIRCVDQRTQEPVREQWLLALCTQYSGTEFQGRRRDALSYSLFHYLVMFMLALNLVPSAVRSHLDHRQMQKFLRTFGDNERQAAVAYGAMFTGIHSGMRQRKAAVSFVSLLVMAVNVVVLLTSSHMTLLDPSSYPFEQYLGETMSQFGHVFPGTAQCRVQPSMMLGAYTDTYGCHFPLSQHYRHILLAMLIVVGVGLVLSLLTFLIDAAMVFAGPSASLVYTACRDPGLERRIARQWTRDELEALRLVRQKTDMDAFVWILSQLDFEEDPVEVVVAGEASSASTEGDLERSLRIELDLSLGDSSSESSSESSSDSSSENRCESSSDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N0W2</accession>
    <name>A0A3R7N0W2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001918">
        <property type="protein sequence ID" value="ROT74260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N0W2"/>
    <dbReference type="STRING" id="6689.A0A3R7N0W2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="437" mass="47249" checksum="FA6FF928DB9C7128" modified="2019-04-10" version="1">MQPVEKRCFPGDSGGIAKRAKVSEQRLACACSVHGAPTRARGHPSPPGTAPPAHPGTAPSPPRRAPGAAPQPTPGRGAPSRAPQPTRHAPPTAPSPPGRGAPATRRGAPHPARRPPARRPAHPGAAPPAHPARRPPTPRRPQHPARPQPSPAHPARRPSHPAAPTSPPPGGAPSPPGRVHEGTRAVILFPNAQALVRGPCILCGRQVARARLERERGLLTERPPLRPSAPPHLAATPPPGRRSGLHFLSSNPMFSEMRLDFAGSGTHGAAVFRLRRLMNPPKRERQRERQTPTRARGLQRLRGGGASLMTSRERPFLLCRNKNCYSRESSARPGTSVKVEIRLRQKRRLTERARKRLGRRNRPKWRRTFPNLRWRPPSALAGPGGRPQHQRARVPAASASVGPKASRQPSRGAEEGGLARSRSAVNVCFWGTFEARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N8I3</accession>
    <name>A0A3R7N8I3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cardiac muscle actin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_001131</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001149">
        <property type="protein sequence ID" value="ROT80133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N8I3"/>
    <dbReference type="STRING" id="6689.A0A3R7N8I3"/>
    <dbReference type="OrthoDB" id="6329537at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="12">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT80133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="731" mass="81272" checksum="679D22082B4722B5" modified="2019-04-10" version="1">MRDANIITLYKSKGERSDCNNNSGISLLSIAGKAFAQVVLKRLQVIAERIYPESQCGFQANRSTIDMVFSLRQLQKCREQRQPLYIAFINLTKAFDLVSRDGLFKILPKIGCPSRLLSIIKSFNENMKGTVIFDGSSDAFNIKIGVKQGCVLEPTLFGIFAVLLKHAFGSATEGIYLRTRSDGKLFNLSRLRAKTKTQLKHLRDFLFADDAAVTTRSAEDLQQLMSRFNNACHDFGLAISLKKTQVMAQDIDIAAAIRISEHGLEDIHDFLYLGSTISDSLSLDFEINKCISKATTTMSRLTKRAWNNIKLTEHTKILIYSACVMSNLLYGSPPASLLPRTRTSACPEVNCKNRNMCDDEATALVIDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEESPVLLTEAPLNPKANREKMTQIMIETFSCPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHCVPIYEGYALPHAIMRLDLAGRDLTDYLMRILTERGYSFTTTAEREIVRDIKEKLCYVALDFEGEMAQAAASSSVEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESSGIHETVYQSIMKCDVDIRKDLYANTVMSGGTTMYPGIADRMQKEITTLAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQSMWISKDEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N8N2</accession>
    <name>A0A3R7N8N2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4'-phosphopantetheine phosphatase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Inactive pantothenic acid kinase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_001042</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(R)-4'-phospho-S-sulfopantetheine + H2O = (R)-S-sulfopantetheine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:68340"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:177302"/>
            <dbReference type="ChEBI" id="CHEBI:177303"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:68341"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer. Interacts with PKM.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001139">
        <property type="protein sequence ID" value="ROT80242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N8N2"/>
    <dbReference type="STRING" id="6689.A0A3R7N8N2"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24123">
        <property type="entry name" value="ASKHA_NBD_PanK-II_Pank4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.510:FF:000008">
        <property type="entry name" value="Pantothenate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1700.10:FF:000001">
        <property type="entry name" value="Pantothenate kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000067">
        <property type="entry name" value="Pantothenate kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10880:FF:000001">
        <property type="entry name" value="Pantothenate kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1700.10">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.20">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035073">
        <property type="entry name" value="At2g17340_3_helix_bundle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00555">
        <property type="entry name" value="panK_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0533">Nickel</keyword>
    <keyword evidence="11" id="KW-0944">Nitration</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="16">
        <location>
            <begin position="464"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00046055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT80242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="792" mass="88523" checksum="D5F21B2AFCC6FADB" modified="2019-04-10" version="1">MEAQKYAGSIQLPDTDVVFRNIKNAKRFAIDIGGSLTKIAYYSTVSHRKVLYNTEKEATNTVDGDDYKYESSETERLHFVKFETKYIEQCLNFIRDHLVNSKESMAGKSIKATGGGAYKYADLIYEKLGLAVEKEDEIGSLIKGCNFLLRNIPDEQFSYSRHEEPEYRFINTEPNIFPYLLVNIGSGVSIMKVESDDKYERIGGTSMGGGTFWGLGSLLTKAKGFDELLHLASEGDHRNVDLLVKDIYGGDYSALGLTGDIIASSFGKAMHHGHTKNDGNPGFSEADIARSLLFTVSNDIGQIASLYAMLHGLKKVYFGGYFLRNHPLSMHTISFAINYWSRGAVQALFLRHEGYLGAIGAFLRGAEECDSEKYSWGENYAGSSGLQSPLPHPPVGGWPGGTIDQLEIDRCDQQLTFFPLLAHPEEYVPDTVDLTKDKEARDYWLSCFEGSLGSFVSRAVSSQPNSIDAVERANRFREKYLQRLHNLKNHPFAYGNLTVRSLLDMREHCLNEFDFPDPYLQQKKFENENALKMLKDHLKYLDSLEWKERQEVLIRGVLAGNVFDWGAKEVVELMEAGLGFKEAAGKLETRPWLHDDLDAWITRQEGRPYKCAVIFLDNSGCDVVLGIIPFARSLLAQDTRVVLCANSKPALNDVTAEELIMLMKQVATVCPIINQHLDSGTLCIRESGQASPCLDLSRLPISLLDELCTWDCDLVVVEGMGRAVHTNLKAVFTCDSLRLAVIKNRWLANRLGGNMFSVMCKYEAGMQKINAAPKSSNISENVIKDCLSVSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NDI1</accession>
    <name>A0A3R7NDI1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative fork head transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022552</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000569">
        <property type="protein sequence ID" value="ROT84257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NDI1"/>
    <dbReference type="STRING" id="6689.A0A3R7NDI1"/>
    <dbReference type="OrthoDB" id="10070006at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20030">
        <property type="entry name" value="FH_FOXN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049624">
        <property type="entry name" value="FOXN1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46721:SF3">
        <property type="entry name" value="FORKHEAD BOX N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46721">
        <property type="entry name" value="FORKHEAD BOX PROTEIN N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="287"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="287"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="413"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="419"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="595" mass="65098" checksum="5EBF6A8C3EE472EB" modified="2019-04-10" version="1">MDLYLPSTEPGLTLQEMIDCDIKCGLDFSEGPDSMITSSDLNSLDLSGMSSLEAELDLKTFEPLFDPLEKLEEMDVTDDHSQDELNVVNSWMNMSSMSNYSLDIENSIMVNPSAVLPTTLPSRVVKSEPVTTTTTPVSSSTSTPTVFIKTEPQDVATTTTLQTPQSQSTNGTTVTTQVTVMRTPSSIGQNIRQQNPMVSTQSTPQTPSQPTVMTRPTVNASQMVVQTTQRSGTQQLTHPSTAATTTPTTTPIITARTTTTHTILNNRYKSTGKPRKDLRPEERVFPKPAYSYSCLIALALKNSTTGSLPVSEIYSFMCEHFPYFRTAPNGWKNSVRHNLSLNKCFEKIEKPVVAGSNQRKGCLWALNPAKAHKMDEEVQKWSKKDLQGIKDAMAHPEVLEALECGEMKFESTGSISSCSEDEDEDEEVDPLTVDSPATPVGTVKRGAQTIVSQSQQQQHIRQPVQNGRTPLSTSVANSAMNHSQARPAFTAQTLKRSPVTSTEEPEYILPDSTMTEISLQSNGALVDDLGNEIKIEGDSPIHTNASPRGLVVRKLPGITPLRSATVRANYMYTPTISSPHQPTLNRLVLTNAKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NLN5</accession>
    <name>A0A3R7NLN5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Succinate-semialdehyde dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="3">1.2.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NAD(+)-dependent succinic semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020687</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.24" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01004126">
        <property type="protein sequence ID" value="ROT61524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NLN5"/>
    <dbReference type="STRING" id="6689.A0A3R7NLN5"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="248" mass="26511" checksum="E293A72744EF337B" modified="2019-04-10" version="1">MRGPTKWIYQRCGTTIKKLSLELGGDAPFIVFPSADVGKAVKGALAAKFRNAGQTCVAANRIFVHESVHDEFVKQIAEAMDAELKSGHGLENGVNHGPIINQRQFDRLVKMIDESIAAGAKVVRGGKPGGGLFYPPTLLTGITLDMPVAKEEIFGPVAAILKFREEEEVVRLANGTAMGLAGYFYTGDVGQAWRVAEALEVGMVGVNEPMVSTCEAPFGGVKQSGLGKEGSLHGLDDYTHIKYICFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NPL2</accession>
    <name>A0A3R7NPL2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003448">
        <property type="protein sequence ID" value="ROT63369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NPL2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="710" mass="77913" checksum="6F0FE066A4D5CCF1" modified="2019-04-10" version="1">MWSFFSFFFFSFTLLMSLPFLRIIISLPLHHHHSSLLLPLSFLSPLIPLLPFIPSASSSSCRLVLSPSPFTLCLFLSLIITLHSHHLSFFLSSSSLHSLSSSSTIITLHSYHLSSSFHPHHSSSSLHPPVPPPPSSFFTLLMSLSFHHHHPPLLSPLFLPFTLPSTPITPPPFLPQCLFHHHHPHSYHFFLPFTLPSTHYSSLSPPVPLPPPSPSTPITSLPSFPPSFHPIIPLLPFLPQCLFHHHHPPLLSPLFLLFPLPSTPIIPLLPFLPSASSTTITLHSYHLSSFFPLPSTPITPLLPFLPQCLFHHHHPPLLSPLFLLSPFLPPHYSSSPLSPSVPLPPPSPSTPITLFLLSPFLPPHYSSSPFSPPVPLHHHHPPLLSPLFLPSIPITPPPLSPPSASSPPSPSTPITSLPSFPPSFHPHYSSSPLSPQCLFHHHHPPLLSPLFLLSPFLPPPFFFFSPFSPQCLLHHHHPPLLSPLFLLSPLPSTPITLFSPFSPSASSTTITLHSYHLSSFFSPFLPPPLLLFSPFSPSASSSCVAWTPANPGSAATQSAPLPGSPRPSRRSDPRPLGTECPADLPPRLLQVATAEGRLWSLLVRIPRRPEGFRHQGGGGGIERRFFPTSILRPPPRRIPNPNPIRKPLLNLRILQKLCEREEVLDMAARVKQLGAVLALKALVILTRVLSAAVVGEVGLALPWGLEGVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NPP9</accession>
    <name>A0A3R7NPP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Trithorax</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003438">
        <property type="protein sequence ID" value="ROT63450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NPP9"/>
    <dbReference type="STRING" id="6689.A0A3R7NPP9"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042800">
        <property type="term" value="F:histone H3K4 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45838:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE TRITHORAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45838">
        <property type="entry name" value="HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="7">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="98" mass="11528" checksum="21C37E87D696DB52" modified="2019-04-10" version="1">MREKDYESKGIGCYMFRIDDDTVIDATMHGNAARFINHSCDPNCYSRVVDILGKKHIIIFALRRILRGEELTYDYKFPIEEDKIPCTCGTRRCRKYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NVY1</accession>
    <name>A0A3R7NVY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002713">
        <property type="protein sequence ID" value="ROT68148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NVY1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="119" mass="13411" checksum="2E709B1F1FDA7763" modified="2019-04-10" version="1">MTRTQLVEQIIGYLLTSTYDTRDTNKEEFTTTPGGACLRTSAGQKSQDEILLITSLRRLSLHICLRGGTSLDSLRRETNERRRKGFRDLEEDLNVDSLSRRHDLHAACPANTLSSMTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-08-03" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6U2</accession>
    <name>A0A3R7P6U2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative DNA-directed RNA polymerase II subunit RPB1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003570">
        <property type="protein sequence ID" value="ROT62642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3728" mass="421087" checksum="0E5F0C4819AB7606" modified="2019-04-10" version="1" fragment="single">RPRVFSPILSSSSLRFYRISLHLTPCLLRFYPRISLHLTPCLLSDLSSHFPSSHPVSSLRFYPRISLHLTPCLLSDLSSHFPSSHPVSSLRFYPRISLHLTRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCSSPILSSHFLHLTPCLLSDFILAFPFISPRVFFSPILSSHFPSSHPVSSLRFILAFPFISPVSSLRFYPRISLHLIPVSSLRFYPRISLHLTPCLLSDFILAFPSSHPVSSLRFYPRISLHLTPCLPILSSHFPSSHPALFPSSHPVSSLRFLSSHFPSSHPVSSLRRVVHLSSSHPCLLSDFILVPSPILSSHFPSSPPCLLSDFILAFPSSHPRVFSPILSSHFPSSHPVSSLRFYPRISFISSPCLLSILSSHFPSSHPVSSLRFYPRISLHLTPCLLSILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVLLSDFISHFPSSHPVSSLRFYPRIFPSSHPVSSLRFYPRISLHLTPCLLSDFYPRISLLHPVSSLRFYPRISLHLTPCLLSDFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSSDFILAFLHLTPCLLSDFILAVSSLLHPFTPIRRFFFRSYPRISLHLIPFSSPFSSHFISHFPSSQSPCHSPFILVPSSPRFSRSPLSSPLHLTPCRSSLRFLSSHFPFISPRVFLSDFILAFPFISPRVFSPIFPRISLHFIPVSVFSPILSSHFPSSHPVFFALSHPVSSLRFYPRISFILTPCLLSILSSHFPSSSHPRVFSPILSSHFPSSSPRVFSPILSSHFLHLTPCLLPILSSHFPSSHPVSSLRFSSSISRFISPRVFSPILSSHFLLSSPPQSFLRFYPRIPLSSPRVFLSILSSHFPSSSSPCLLSDFYPRISLHLTPCLLSDFILAFPFISPRSLLSDFYPRISFISPVSSLRFYPRISLHLIPVSSLRFFPRIFPSSHPVSSLRFYPRISLHLTPCLSLRFYPRISFISPRRLHLEFYSSHFPSFTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFILAFPFISVSSLRFYPRISLHLTPCLLSDFILAFPFISSPCLLLRFYPRISLISSPCLLSDFILHFPSSHPVSSSPILSSHFPSSHPCLLSDFPRISLHLTPCLLSDFILAFPFHLIPCLLSDFILAFPFISPRVFSPIFILAFPFISPRVFSPILSSHFPSSHLRRHLTPLRSHHLPVSSLHFLHLISFYQCHSSHFLHLTPCLLSDFYPRIPSSHPCLLSDFILAFPSSHPVSSLRFYSSHFPSSHPGVFSPSHFPSSHSDFILDFHRSHFPLHLVSSPILSFFNPVHLIYSSSISSHPCLFSPILAHPCLLSFSLFSPISSVSSLDFILAFPFIFTRVFSPILSSHFPSSHPCLLSDFILAFISPRVFSPILSSHFPSSHPRVFSPILSSHFPSSHPVSSLDFILAFPFISPRVFSPILSSLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTRVFSPILSSHFPSSPCLLSDFILAFPFISPRVFSPIYPRISFISPRVFLSDFILAFPFISSPCLLSDFILAFPFISPRVFSRFYLAFPFISPRVFSRFYPRISLHLTRVFSPIFILAFPFISPRVFSPILSSHFPSSHPVSSLDFILAFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPFLTPCLSLRFILAFSLHLTPCLLSDFILAFPFISPRVFLRFYPRISLHLTPCLLSILSSHFPSSHSLRFYPRISLHLTPCLLSDFILAFPFIHPVSSLRFYPRISLHLTPCLLSDFILAFPSSHPCLLSDFILAFPFISPRVFSPIYPRISLHLTPCLLSGISLHLTPCLLRFYPRISLHLTRVFSPILSSHFPSSHPVSSLRFYPRISPRVFLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPIYPRISLHLTPCLLSDLSSHFPSSHPVSSLRFYPRISLHLTPCLLSDLSSHFLHLTPCLLSIYPRPSSHPVSSLRFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSRFYPRISLHLTPCLLSDFLAFIHPVSSLRFILAFPFISPRVFSPIYPRISLHLIPCLLSDFILAFPFISRFILAPSSHPCLLSDFISHFPSSHPCLLSDFSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFISHFPSSHPVSSLRFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPHFPSSHPVSSLRFYPRISLHLTPCLLSDLSSHFPSSHPVSSLRFYLAFPFTPCLLSILSSHFPSSHPVSSLRFTRISLHLTPCLPSDLSRHLSRFLSRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSVPHLIPVSSLDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLIPVSHFPSSHPVSSDFILAFPSSHPCLLSDFISHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSILSSHFPSSHPVSSLRFLSSHFPSSHPVSSLRFYPRISLHLIPCLLSDFILAFPFISSRVFSPILSSHFPSSHPVSSRFYLAFPFISPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPCLLSDFILAFPFISPRVFSPILSSHFPSSHPCLLSDLSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTRVFSDFISHSLHLTRAILSSHFPSSHPVSSLRFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFYPRISLHLTPCLLSDFILAFPFISPRVFSPIYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYLAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPVFSPILSSHFPSSHPRVFSPIYLAFPFISPRVFSPIYPRISLHLTPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFILAFPFISPVSSLRFILVIFSPIYPRISLHLTRVFSPIYLAFPFISPVSSLRFYPRISLHLTRVFSPILSSHFPSSHPVSFSPILSSHFPSSHPVSSLRFILAFPFISPRVFSPILSSHFPSSHPVSSSDFILAFPFISPRVFSPIYPRISLHLTRVFSPILSSHFPSSHPVSSLRFYPRISLHLTPCLLSDFILAFPFISSPCLLSDFILAFPFISPRVFSPILSSHFPSSHPVSSLRFYPRISLSSHPVSSLRFHPRISLHLTRVFSPILSSHFPSSHPRVFSPILSSHFPSSHLSDLSSHFPSSHPCLLSDLSSHFPSSHPVSSLRFYPRISLHLTPCLLSDLSSHFPSSHPRVFSPILSSHFPSSHPRVFSPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P8T0</accession>
    <name>A0A3R7P8T0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vitelline membrane outer layer protein I-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001345">
        <property type="protein sequence ID" value="ROT78705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P8T0"/>
    <dbReference type="OrthoDB" id="6329319at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841:SF0">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018687120" evidence="1">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="23874" checksum="F57C31FDBE7CBECF" modified="2019-04-10" version="1">MILWSVAFLLAAGAWAADEEPRDESHITLALDWAMNWGEWGPQVYCPLGTFAYAFQIKVEGEDHLDDTAMNGIELFCRAPADTGHDGRPPKKDAKEFTITSTVQQWGDWKGKRECATGYLTGLRMKSEEDQGFFIDDTAANDLEMQCHWSTDTLNGGGDHWGTWSSWESCPHNWAICGIETRVEADSATDDTALNNVRMFCCSLNDMPPTLAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCN9</accession>
    <name>A0A3R7PCN9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002885">
        <property type="protein sequence ID" value="ROT66808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCN9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="42100" checksum="18903FED400344B5" modified="2019-04-10" version="1">MDLEIHGTSRDRSSLGYSACGRASLQQPGTVSSQQHSGTAASSQRRTAQSSSQQPAQRRPGTASSQQPGTASSQHTAGVTTAGHSVVTTAGHSVVTTAGHSVVTTAGHSRSQQPGTASSQQPAQRRHNSRAQRRHNSRHSVTTQGTASQQPGTQSQQPAQRRHNSRHITASSRRHNSRAQRRHNSRAQRRHNSGTASSQQPGTASSQRRTAGHSVVTTAGTARRAQSQQPGTASSQQAQRRRRHNSRHSVVTTAQVVKQQSSQQHSHNSRAQRRHNSGHSATAGHSVVTTGHSVVTTAGHSVVTQPGTASSSQYSVVTTAGHSVVTAAGRSVVTTAGHSVVTAAGHSVVTTAGHSVVTAVTASSTAGHSVVTTAGHSVVTAAGHSVVVTLARGRDCCTLTSVIVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFF0</accession>
    <name>A0A3R7PFF0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011884</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="QCYY01002503">
        <property type="protein sequence ID" value="ROT69896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFF0"/>
    <dbReference type="STRING" id="6689.A0A3R7PFF0"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000006">
        <property type="entry name" value="Alpha-(1,3)-fucosyltransferase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031481">
        <property type="entry name" value="Glyco_tran_10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17039">
        <property type="entry name" value="Glyco_tran_10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="108"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="245"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT69896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="52069" checksum="9B705600473647FE" modified="2019-04-10" version="1">MGVLLRNHVSWTLRKVVLLVFCLGCALHFLLGEKEDIIGMVRINRAKEEVCSCHVSREAIETETLTKRAQNATMKDWRNLTAEELGSLSVLGRYLYLEEPLGAPQDRTFLILIWKKGLYMEQRLLYEFTSKRKDPFARCSVRNCKLTYEDEDVRIADAVVFHLHTTPGPQDFPNRTRASQRWIWLTGESPFHTFMIAEDKDISHYNGYFNWSMNYRMDSDIPVPYGRTLKLADGERPNITIDYFSTKSKLVAIMGSNCGGQNGRWKYVHELEKHLELDTYGGCGKLKCPGHFAIDCSALNQYKFYLAFENGNCPEYITEKVWWNSFHKGVVPVVMGGPKESYRKILPPNSFIHIDDFETPKDLAEHLKALSTNRQAYNDLHAWRSEYRVSNEHAYFQSPIYHYCRICEALNHNDPKPKVYNRMQDFWKVDGHCPPPTWKDRLKKTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGP1</accession>
    <name>A0A3R7PGP1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate dehydrogenase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.4.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_010495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-glutamate + NADP(+) + H2O = 2-oxoglutarate + NH4(+) + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.3" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002331">
        <property type="protein sequence ID" value="ROT71205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGP1"/>
    <dbReference type="STRING" id="6689.A0A3R7PGP1"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000007">
        <property type="entry name" value="Glutamate dehydrogenase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000100">
        <property type="entry name" value="Glutamate dehydrogenase 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF13">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="452"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT71205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="746" mass="82374" checksum="F7123A61BEDFB108" modified="2019-04-10" version="1">MLSEVFNSRKKHSYQTIYRASSSTTENDIEEDTNNDVDDYNSSITTQVTTFTLSDGTTTEFVMNKVSEAFVDDLISIGSDFYPLPMAYNNVYAESESPEAAAPTFGENLTRCPENSPLHTTHFLHVAVRLQPCGINIAPTQRSMASPDMAPLKIRFSASPPTSLSFKATSSVSLPSVSTSAQLGEAHHGARKLNMLRLGTSVVRAVVQAGAAETLLKASAPAAGVAKRWQGDYERHQIPERLQYIPDAEDPSFFEMVEYFFHRGCQVVEDQLVEEMKERIPLEEKRNKTRGILKIMEPCHHVLEVAFPVKRDNGTYEMIHGYRAQHSLHRTPTKGGIRYSLDVCADEVKALSALMTFKCSCVDVPFGGAKAGLKINPRDYSINELEKITRRFTLELAKKGFIGPGVDVPAPDMGTGEREMSWIADTYANTIGHLDINAHACVTGKPINQGGIHGRTSATGRGVFHGLENFINEASYMSMIGITPGWGGKTFIVQGFGNVGLHSMRYLHRAGATCIGIKEVDGSIYNPNGIDPKELENWKIENGTIMGFPGAETYEGENLLYEKCDILIPAAIEKVIHKGNAHKIQAKIIAEAANGPTTPAADQVLQDMNVLVIPDLYINAGGVTVSYFEWLKNLNHVSYGRLTFKYERESNYHLLESVQESLERRFGRVGGKIPIVPSEAFQDRISGASEKDIVHSGLDYSMERSARAIMRTAIKYNLGIDLRTAAYVNSIEKIFNTYKEAGLTFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIL7</accession>
    <name>A0A3R7PIL7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nbr1 FW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_014082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002757">
        <property type="protein sequence ID" value="ROT67794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIL7"/>
    <dbReference type="STRING" id="6689.A0A3R7PIL7"/>
    <dbReference type="OrthoDB" id="6355654at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14319">
        <property type="entry name" value="UBA_NBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000199">
        <property type="entry name" value="next to BRCA1 gene 1 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="Nbr1_FW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nbr1 FW" evidence="7">
        <location>
            <begin position="118"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="473"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="577"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="683"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="585"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="683"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="706"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="774" mass="85416" checksum="2EF1396AFCEC1C73" modified="2019-04-10" version="1">MDKASRTQEKVLAKMEGLRKKQSCSPEELNKLRKMVDKQHRVITAEQRQQRRNDRKAGNQKAGKSKKFNIDNKGFPVDASLLHAALQELEALAEDSPNEGTAGISTRGYDALYLHDVTYPDGSEVAPGTEFVKTWRVANTGVEPWNEKTTLCKWSQVRFRGSPAGWKLKPSSKKVVCPPLEPGQEGDISITFTAPSEPGWYATHWRFCQRGRVFGNQMWCAIYVADRNVREKLEPVQGEDVASAVRLMLSVSPKQCLSKGSAVSEETVCDKEEEEEEEEEEEEEEEEGAKALRSSQIKGDLEGGIVENYYDAEDPFEKELRKNLKSLSLCTSVKTEGTEVRRTERDLISFEEEAEVVSSGTTTPEMIQDIPQTHAVVPLKEMAKESVESLRESMVGKEQESGKKESCRPKVFQADTLSISSGSFSELDSEDQAILNESDTEYSDNEYCLVNLPECFNVPSPYNGLAESVVQDMHEVDRPDSPDFLTADEDDRTTAVASDLQDDQAESVEGSGGSSNNSTTSQGSHLSTVVEVSQEKAQTPPQAESGKKMPMPDPPTDTKPFMEVPAEALRANLAYAVQQSSGNRSSEEGEESKSKDDTTWSLSAQAAHSVVCEQPSSTQHKDHRPLSRCIDGKAAAIAAGGTDLPLDLVGALPDELVSIIPEDLVRGAWNTARSFITRINQEMLSPTGTDSPDQIYASEESSAPKSEPKETTQKEEPVQKEESPSKRRTSPLPPPMQQLEDMGFGNREVNQRLLTKYNNDVSCAVAELIVLNCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKT3</accession>
    <name>A0A3R7PKT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Venom allergen 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001811">
        <property type="protein sequence ID" value="ROT75088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKT3"/>
    <dbReference type="OrthoDB" id="414826at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="198"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="334" mass="36486" checksum="B849C80FD8709530" modified="2019-04-10" version="1">MSFYSFFPLLPLLPPPPLAPPLLLPLYLSLLPIHLPPPPCQLDSTWVRTSIFSPICLSFVFILSLSSLSLSLSPSPSSSTSLPIPFVPLSSTLFLPPPPLPLPLHSNFLPNSSFFLLSSTLFHPPPSSPSSSSSTSLTYSYIFFPFFSVGQNLPSPPPSTLLLPLHLPLSATNLSSPPPSSLSPLLPSPLLLPLPLSSLPNSFFFPFSARFGVGQTSTLFSLPLFSYPLLPPLLLPRFGVGQNLYSAGDFKLKPVDWNRPLNAFFDEVDMMDKSEVDSFLGNRGVGHYTQLVWGATSHVGCGYIAYKNNRYIQSYYACNYGQAGEFRKEEGVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMS6</accession>
    <name>A0A3R7PMS6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pseudouridine synthase II N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002279">
        <property type="protein sequence ID" value="ROT71569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMS6"/>
    <dbReference type="STRING" id="6689.A0A3R7PMS6"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029245">
        <property type="entry name" value="DUF4528"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039048">
        <property type="entry name" value="Trub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13195">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13195:SF0">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15031">
        <property type="entry name" value="DUF4528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="2">
        <location>
            <begin position="207"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="45157" checksum="DAE13547760C6945" modified="2019-04-10" version="1">MHVSQTLKIFRRIKEAKPTASLVLTTHLRQRQLPHWTSYFVKYSDVTSDQRGLSHFNWKVDGANYHILRTGCWPYMKYHCTKRPYEDLSVDDKFFRVLKIANLGIPCLAYGCGASFLISCQEDIYTPEGTVTIYFLYEEDRDMTMNHLRKVLIGNLSRDLNLLKTRPATPMVAIEGSVTENLVVKVKENYADHPLVLGPRYQPKDIKLAWAHQLDKNISGVCILGVNSGTKGTHKVRESQLIRSYMVSGQFGRTTDTLFNDGKVIGKSTYKHVTRGRLMRTLMTIQAGHQRSALHFLGLDPQSQEAYEALSADGLVRPGEKSPPLIYALKIVDFNLPDFTLEVSCINENAVYLQHLVHDLALRLKTTAVCTQMRCIRYGPWTLQHSLCGILEPEALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQB2</accession>
    <name>A0A3R7PQB2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001993">
        <property type="protein sequence ID" value="ROT73780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQB2"/>
    <dbReference type="OrthoDB" id="6373683at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="123" mass="14074" checksum="3AA650257C2ED041" modified="2019-04-10" version="1" fragment="single">MARSSKGKAAKRVKKGRIPRYAPKLEKQLLSIVKKAEENNALPKVVGRIPKVELLEPKEEKNAEEAETMDTNQPEVEVKVKEEVMSDTGSIMGNDKKGIFKKLYTVRQMRKRKINKNKAKRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRE3</accession>
    <name>A0A3R7PRE3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WSC domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006811</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WSCD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001862">
        <property type="protein sequence ID" value="ROT74682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRE3"/>
    <dbReference type="STRING" id="6689.A0A3R7PRE3"/>
    <dbReference type="OrthoDB" id="6351622at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF9">
        <property type="entry name" value="SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018760840" evidence="2">
        <location>
            <begin position="26"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="107"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="265" mass="31187" checksum="37D9BC34C4A756ED" modified="2019-04-10" version="1">MARLRPLKHFVLLVIFFWAVKILHSKKDNLTPFNQRLQEVVLEGRRPWEVEDYLAEEDVDDGVVEDEKVKEYEEGRGEGYLGERHKYGWGTTIATKSHFIKHLQKYRNVPTVTIIRNPARVFVSLWSYVNLQNRRRKHVESVAESSLRTQEFHDFVQSKLKKWLNTTLFSLTQCRDVFPVFYESVREDPVGETRRILEYLKVKPQEDRLACLGRHVGGNVKGAQKSLDPYTQEEKELFLQALKKVNETLTQRGFPTLPDYSKYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTM7</accession>
    <name>A0A3R7PTM7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000848">
        <property type="protein sequence ID" value="ROT82300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTM7"/>
    <dbReference type="STRING" id="6689.A0A3R7PTM7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="48665" checksum="B24637B7024AA8E1" modified="2019-04-10" version="1">MNASVSFGPQPPTNPVHAHPFVPRHRPRSRPTHFRPTAHLPGHAHPFATPTLPGGSVDGGERTRMWGRPDGPTNPVHAPPIRSRGGPRGAREARGGGSRAAGAGWRRATPTNPGCVRTPEGWHGRPARRRARGGQRASCASGATQVRRRRGGQAELGGAEQPHAASVRGAAERGGGGPKRRVWTGPLWRSGRHRPVGGCPDAARLRRAFERADHSVPGDAPGAGRAPVRRRRRCGHIFGAASGGRRARCVGGPTPTNPVAAGRGAEIHSFHAPTRFTPIPFVLRFPLPPSSTPTSPRPTNPFTAHPFVPSFNIHSAHAHPFAPRPPTRFTPTHSSHAHQPGSRPSIRPTPTNPVPAHPLSHATIHAHPFVPRPPTRFTPTYPVHAHPFVPRPPTRFTPTHSHRTPSHTHTLASRSPLPPFPERCHARRFPGAARAPPRPRCDARHVATELDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWD2</accession>
    <name>A0A3R7PWD2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004090">
        <property type="protein sequence ID" value="ROT61596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWD2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="43259" checksum="7B9D2D1AA4EB5C62" modified="2019-04-10" version="1">MHLSTNEHIHALSSLLSSSFPFPFPLPPHHLLLLLLFLLFLFSSPPSYSSSSSSLLLPSSSFLLLLLFLLPTPSPLPSFPNLLLPSLHHFLLPFPNLPSSPLLTTSSPPSSSSSPTPSFVEVDTTARFTPVPFIPSSPFSTPASSTPLPFPSSPSPFLLTPFPVIPAPSIPSSPSPLPFSPLPVTPTPSSPSPFPLPFLSLPVTLHPPSPLNLFPVSLVSSSNSPPLPLTNAKGRRNVEGKEPSLLPSPPTLSLTLPLHPPTFYLSSTLLFNTLLLLPLTPASLLFLHPLPLTPSSSPPSLNPFLLLPFPLSTSSLLFILLPLPLTLLPFPPLSPSLNAFLPPPAPPLNAFLPPLPLNPSPPSPPSSTFHPNSPSPSPSTFHTGPPFPLPRPSTQPPFLPPLLPSPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZD8</accession>
    <name>A0A3R7PZD8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase-like 26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0585 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003260">
        <property type="protein sequence ID" value="ROT64366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZD8"/>
    <dbReference type="STRING" id="6689.A0A3R7PZD8"/>
    <dbReference type="OrthoDB" id="10258744at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010342">
        <property type="entry name" value="DUF938"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974">
        <property type="entry name" value="UPF0585 PROTEIN CG18661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20974:SF0">
        <property type="entry name" value="UPF0585 PROTEIN CG18661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06080">
        <property type="entry name" value="DUF938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="25549" checksum="CBDD87D206430F65" modified="2019-04-10" version="1">MGYVARRLYSTLRGIMAEAKLVIKAPENNKDPIFQVLEKVIPEKFGSDSGLTALEISSGSGQHVSYFARKFPSISWQPSDIEDKYIKSIKCYIEDDKCENVKEPVIIDISKPLSEWASPIAEKSINMMVNINMVHISPWACTEGLFAAAGKLLKPGGILITYGPYSIHGEITPESNVNFNASLKEQNFEWGLRDVDELEKEAKKNGLVFDAMFDMPANNKTLVWQKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q003</accession>
    <name>A0A3R7Q003_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024383</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000821">
        <property type="protein sequence ID" value="ROT82458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q003"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41694" checksum="35B473325AA4BBB8" modified="2019-04-10" version="1">MLFIRFVMGMMQPTSIHAGYTLAMEVNEPKYRAAVGVLIFLPWALTVIVLGGYGYLLRDWRWFGVTTSLPCLLFLPMLLFLDESPRWLIVRGRHDDALRILRKAARWNKAQLPPEEELRALMDLIRKEALTASTESAASSSGLVKSLKNIMEDVIVLVRTRRMRSITLSFYAQFFVLGMVYYGLSFGADKLGVDPFVYMAVSGVMEVPGGTLTIPLVEKMGRRASSTLFFVITAGSLLVLGFIPDALEWLVITMAMLGRLAISVAFQVVYLYASELFPTEVRVRGLGTCTMQTTVGAMLAPFILEILGSIKSWVPLFVCGVAAFVASVTTFWLPESRTASMLDTVASLEAAHSGAKESRAASLDREMENKETDAQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAX0</accession>
    <name>A0A3R7QAX0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) kinase</fullName>
            <ecNumber evidence="2">2.7.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003823">
        <property type="protein sequence ID" value="ROT62115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAX0"/>
    <dbReference type="STRING" id="6689.A0A3R7QAX0"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="264" mass="28634" checksum="93746E5F56A15816" modified="2019-04-10" version="1">MRRRSAEGRPMRSRQPLTVLLGKGGGAEKRMLVFVEASVMEESLVTSHSGFPVLKDKLMSFREGQDDLTDKIDFIICLGGDGTLLYASSLFQQSVPPVMAFHLGSLGFLTPFKFDNFQDQVTNVLEGHAALTLRSRLRCIILRKDQETGKGGCPPTNLLVLNEVVIDRGPSPYLSNIDLYLDGKRITSVQGDGLIVSTPTGSTAYAVAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKVRTLLSSSFLVRKTVFIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QEF9</accession>
    <name>A0A3R7QEF9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001688">
        <property type="protein sequence ID" value="ROT76145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QEF9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="464"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="54515" checksum="1F0ED37E691AC5D2" modified="2019-04-10" version="1">MMVQWMGRCTYARISDASGTSEPLGCSLLKYSNTLFPYPHLSFPSILLLLTSFFLLRLSFLITLSFLLLPYHRHHPQPIPTITKFPYPLPHLCLLIPYMNTQSLPFTPTTPPSSSPHPHPPSSPHHPIFLFPPISSILPTHPTLLFSPTAHPSSSPHHHPIFLFPPTTLSSFPPSPHLPLLPPAPPSSPPPAYLPVPPTTPPSSSSPPPHPPLPPTTTLSSYSPTTYPLFSPPPTLLFPTTPSFLFPPPPHPPLPPPPHPPLPPTPPPIFLFPHHPTLLFSPTHPPLLPTTPPSSSPTTPPSSSPTAPPSSSPHTPPSSSPTTTHLLVSPTTHPPSSSPPPPPTFLFPPPPTLLFPPPPPTLLFPPPPHLLFPPPPPHPPLPPTTTTLLFPPTTPPSSSPHHHPSSSSPPAPPHPLPPPPPSCFPHRLPPPSSPHHPLLFPPPPPPPLPPATTHQHPPSPPPHLLVSPTPTIPSSYSPPPHPPLPSCTTFLPFNYKGTVFETNLPGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QF35</accession>
    <name>A0A3R7QF35_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxinectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003085">
        <property type="protein sequence ID" value="ROT65427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QF35"/>
    <dbReference type="SMR" id="A0A3R7QF35"/>
    <dbReference type="STRING" id="6689.A0A3R7QF35"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09823">
        <property type="entry name" value="peroxinectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.640.10:FF:000003">
        <property type="entry name" value="chorion peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018749460" evidence="7">
        <location>
            <begin position="22"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="554"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR619791-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="798" mass="87658" checksum="42ADBDF1D2092626" modified="2019-04-10" version="1">MILAVALCLAAAAASIQPACGAEEYRVARVIRQINQGNRGSFSSASSGFQSGGGAGGCICAPIIFCAQELRQIQQQCTLPGNIPGVCCPPSTLAASASAPGTGDNNVFASARVQVNLQPLDNSALGQAFNKGIADLTNLQQIEERLFRNNIFLQRGTPAYAHLRVFTISPPAKRRHLNAFAVAMASVHIMQDLSLTRQQGGFGLQQIDVRNTILSDRCPSVPSCNLRNKYRTADGSCNNPRQPTWGQSNTPVQRILPARYDDGVLSPRSRSTDGSPLPNPRVIASNILVDVDNPDQQFTSSVMQWAQFLDHDFAHIPFPVMGNGEGIECCPEGREAQGDNRHPMCMPINTADDRFLAPRGSSCMNFVRSMFSLETSCNFGHAEQLNQLTHWIDGSNVYGSTLEEQRALRTGQGGLLKTSGNNMLPINPDQGGDCSAGDRGALCLQAGDSRVNEQPGLTAIHTLWLREHNRVARALQQLNPSWPDEAVFQQARRIVVAEMQHITYNEWLPIIVGPNFMRAFGINVKNTGFSFDYNPNINANMNNEFSTAAFRFGHTLVQGTLRLFSGDGSVSTIQLRDHFNSPHLISRPGMLDPIVRSFTQLAIQKFDPFITQDLTNHLFQTPRFNFGMDLMSLNIQRGRDHAIATYNDMRAICGLPRATDFQGITDQIPTAIAQNLARVYKSVDDIDFFVGGISERPVSGGLLGWTFLCVVGDQFARLKKGDRFFYDLGGQPGSFSEAQLQEIRRSSWARIICDNSDNIQAVQPLAFMLTNTRFNQPIACNSPVIPRPNLEAWRGEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJF3</accession>
    <name>A0A3R7QJF3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001073">
        <property type="protein sequence ID" value="ROT80759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJF3"/>
    <dbReference type="OrthoDB" id="10490968at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018748629" evidence="2">
        <location>
            <begin position="25"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="20167" checksum="FE60BBFEF866E1D4" modified="2019-04-10" version="1">MAVIRRVRGVSVVFLLVWLGLAGAQDVVRAQQLSLEDLPLIFLPVSRARKLSVVPAVPRRFTAAPRSSRRPFPPRSSRQTSGAVTKVLVTPATRHPNHLRGPGAAAPTPAFFSKPTIRRGSTIATIRFRVPDRKPSRSLDGQDGVFPALIGFVHRPSRRSTKEADAHAFGGRLLSSPIGLLYGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLS6</accession>
    <name>A0A3R7QLS6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Deoxyribonuclease TATDN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023780</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Deoxyribonuclease which catalyzes (in vitro) the decatenation of kinetoplast DNA, which are circular DNA catenated to each other, producing linear DNA molecules. Plays an important role in chromosomal segregation and cell cycle progression during eye development probably via its DNA decatenation activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000747">
        <property type="protein sequence ID" value="ROT83044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLS6"/>
    <dbReference type="STRING" id="6689.A0A3R7QLS6"/>
    <dbReference type="OrthoDB" id="413993at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008310">
        <property type="term" value="F:single-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000018">
        <property type="entry name" value="3'-5' ssDNA/RNA exonuclease TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="34967" checksum="0CC52C17814CA127" modified="2019-04-10" version="1">MASNEANKNQGIDGIEDAMGELMSSENYIIVDIGANLTNKKFTRDLDSVVSRARDAGVHKIMVTGITVQSSKEALRLTRLFPETLYSTAGVHPHEAKTWDDETEEALRELAANQEVVAIGECGLDFNRNFSPQDVQLEVFEKQVSLACELRKPLFVHERDAHKEVLEVLGKYKARLPPVVIHCFTGDATQAAAYLKEGCYIGLTGYVWKDKSEDGVRRILEDGVVPLDRLLVETDSPFMYPNTRASKLPPYVKEALTERSLTFLHRYCTFQRNEPCSLPVTIEMIAAYMKKKSEQVALQTTFNALKVFGLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QM24</accession>
    <name>A0A3R7QM24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Septin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000693">
        <property type="protein sequence ID" value="ROT83391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QM24"/>
    <dbReference type="STRING" id="6689.A0A3R7QM24"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="308" mass="34137" checksum="E65BFD83E54F1EB4" modified="2019-04-10" version="1">MGKSTLMDTLFNTSFESNPAPHTLPSVKLKSHTYELQESNVRLKLTIVDTVGYGDQINKEDSFTAIVDYIDKQFDDYLQEELKIKRCLSAYHDARIHACLYFICPTGHGLKSIDLVCMKKLDSKVNVIPIIAKADTISKAELTKFKQRIIQEIKANNIQIYQFPTDDDTMAKLFLKSSPLLSSLLSLSPRSPYSFFLTSPPSLLTSLPLSFPPDYSPPLPTHSPPLSPLSPFLLSLSPFSPTAYRLLPLLSLLPLLPLSPPLPLPFLPSLIPSSSPIYSPVPPIFSSFAAPPPSPPLPHCHPVLLKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QND0</accession>
    <name>A0A3R7QND0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_008636</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the WD repeat peroxin-7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002086">
        <property type="protein sequence ID" value="ROT72969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QND0"/>
    <dbReference type="STRING" id="6689.A0A3R7QND0"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005053">
        <property type="term" value="F:peroxisome matrix targeting signal-2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="104"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="148"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="236"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT72969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="36526" checksum="D8A15E9C29A8F2DE" modified="2019-04-10" version="1">MAAKLTRRLPTPNHHGYSVKFCPFNRDVIAVASAQNFGLSGGGMLMVKNLSAPGDGTVSTCIWADGLFDLTFSEQTPNCVVTASGDGSLQLWDVTKSQAPIMVYREHQKEAYSLDWTQTRDSQFFVSSSWDGTIKLWDPNREKSLLTMQGHEALVYQAVWSPHITGCVASVSGDQTLRIWNTKKDTRPVMTIRANQGEVLTCDWCKYNQNIIATAGTDCKIYGWDLRRPGEPVYVLQGHGYPVRRIKYFPFAETQLASVSYDLTTRIWDHSLPNPSLSVLETHSEFVYGLDFSNHVEGLLADCAWDQSVGIYHVLKPGNSGPLTHGGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYQ3</accession>
    <name>A0A3R7QYQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RAC-GTPase activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_023119</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000643">
        <property type="protein sequence ID" value="ROT83716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYQ3"/>
    <dbReference type="STRING" id="6689.A0A3R7QYQ3"/>
    <dbReference type="OrthoDB" id="2218807at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097149">
        <property type="term" value="C:centralspindlin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051256">
        <property type="term" value="P:mitotic spindle midzone assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20821">
        <property type="entry name" value="C1_MgcRacGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04382">
        <property type="entry name" value="RhoGAP_MgcRacGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000033">
        <property type="entry name" value="Rac GTPase-activating protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46199">
        <property type="entry name" value="RAC GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46199:SF3">
        <property type="entry name" value="RAC GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0221">Differentiation</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0744">Spermatogenesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="8">
        <location>
            <begin position="27"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="90"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT83716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="339" mass="38073" checksum="581356580EBFB4E6" modified="2019-04-10" version="1">MYYTPTHTPITPALRTHSSVTKMNQRPHAFYTKTIYKTEHCQPCGKRIKFGKIALKCRDCRATCHPECRESVPLPCVPTANTPTTKGQLGTIADYTSRVPPMVPALVVHCTNEVENRGLSEVGIYRVPGAEKDVKELKDQFLRGKGMPNLSQLDVHVVCGALKDFMRSLKEPLVTHLLWRDFTSAAEKSESQDFLAALYQAISELPQPNRDTLAWIITHLQRVAECPECKMPASNLAKVFGPTLVGYSVPEPDPATMLTETRQQQLVMEKLLEISTDYWNTFINVTDENVYQGVQQLPTPEGGTLLGGFPSSNTRRRSILARTPLTARDTPKNRYVFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYU7</accession>
    <name>A0A3R7QYU7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000627">
        <property type="protein sequence ID" value="ROT83901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYU7"/>
    <dbReference type="STRING" id="6689.A0A3R7QYU7"/>
    <dbReference type="OrthoDB" id="1902038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="408"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="49112" checksum="49D45D3F5D58780D" modified="2019-04-10" version="1">MMEEERQRGLAEEARRERARHEVNLLAAQALTKQMHQQEEVKVVAEAVEQERIKQLRKEQETQLKKAKDDLQLLWLKDEERKLQERKRREELRQVREQEKMEREWRQKAAYPPHPLHIPPYPPSTPSHPHLSPPPSSPHPLPHPPHSPRSEWRQKALEAAYPPPSLTHSPPPPSPLSLLSPTPTPPPHSPPFPPHSPADGTRVAPEGPRSCLSPSPLHSIPLTPSPPSLTPPSPLTPPPSLTPFPPSLPPLMEREWRQRALEAVYPPPPLTQSPPPPSPPTPPYPPPHNSPLILLSLPHPLPIPHPISPLSLPLPHPLPHPLTHPLPPLTPPADGTRVAPAGPGGGAHEGGPRRPGEPGEAPAGGGAPEVPDGGGAGAEEGAAQDIKDKEDYESRIRDQIKYQEAVRAKEADQLKREKEEEALRIKQKEAALVRLKLDTMQELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SL57</accession>
    <name>A0A3R7SL57_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003082">
        <property type="protein sequence ID" value="ROT65474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SL57"/>
    <dbReference type="OrthoDB" id="6352234at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="2">
        <location>
            <begin position="161"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="42523" checksum="AE76F2EEA1BE6902" modified="2019-04-10" version="1">MYTRKHKAEDCPEDGKPHGAFRSVLDIPPRRLRFRRRYPLAPLPSPSPTARQSFSLVIPLTGASSSYARQAGSVSPLSIQSSVESPNKELLFRIRGPLPWNDTELLSLIRDRYLVPPSTLPYNLSTDPLYNRVKHYGSWRFIHKQTKKLIHGFRGGFFVEAGALDGERVSNSLWLEQDLGWNGLLVEPDTENYARLVNKRRKAWITNTCLSPVTYPQEVVFVSLTRKKIAEDQFQRTLWEHRGASHILGANVNSSLYDTFYKRSEEEYYKTQCFPLGSMLSALGVTTIDLLSLDIQGVEKSVLRTLPWAQLTVRIIVIEIVNYEKIDHAFIKEMEGIGYILYAYQGEDYIFVRKGDPFLTHAYEENSTEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SP22</accession>
    <name>A0A3R7SP22_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012807</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002613">
        <property type="protein sequence ID" value="ROT69031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SP22"/>
    <dbReference type="STRING" id="6689.A0A3R7SP22"/>
    <dbReference type="OrthoDB" id="6369905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001636">
        <property type="entry name" value="CLUMA_CG004886, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="231"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="528"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="653"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="704"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="763"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="658"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="672"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="714"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="763"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="827"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="850" mass="93957" checksum="8810B8BFCF717D24" modified="2019-04-10" version="1">MKFSHPLYYRMHCSVFHDPNYSLTIRKYHCKVCGLAVLGKENIMRHAAEQHEGRGAYQCQYCKKFFLRLNYLDMHRTYGCAANPQRTRPLCDFCGRKFCQPQKLKVHIKRMHSDMAEVLREFQCKLCFKILGSRAALQRHLKEVHHKDLSTGATCDRCGKMFQNKSNLKIHMLTHSGVKPFKCIEASCNAAFTTKQCLQFHYKKVHGYSGDNMPKIERCIPYTFDSYSGGLVNDPARKAPPEPRSEPEQPEPSTPTPTEPPAPEDSSQSSDPPLAPLTPTEGPPTSRADLLLAAAAKLPPAATLHGYVTKYAAATRLVSKGSRKWLGDPMDMPDRDYNERDVYDFDDKLDEDLLQKRKKDEECGGEDKLYRRESTASLLVEAALNVAEQNMKMDSRNIGSHDRLLGYSGRYSPLPPATVVTSIEQILPHDAALATHIKYTTSAADDERAHLEYTLEREYDPRDLPEVMVVHETIGSRDLHDQLSHDLQDNLHAALDHLPPTSVNDDLHHSHHHVQHSDHAHNLALVKSDELPPPTPATPVDPGTPMAPPTPLSSSGGLEPTLHVLDQLPVTQGLPVSLSSLSVGLDMSYKHYRHAELTPVSQEHCLAGQLDDSEASMGLDPMGESGQLSPRNDHLADQLPLPELQPHDFRGLAALRSPEPPRSPYLSPSPLPTRCAPTPRTRTGCARRCRWTSAWTCRAGTCSSGPPTWPACSRGTTARSATSPGGRSYTTLSCTERTPPPRPPPDQDHFIALTAVSSQSVISSQPALASQPTLPNNQLSPHNQLSPNNQLSPHTQLPPYSQLSPHGQMSPLVSLGMVERGGVGSPPLSPTTNPSPPSAASWRPRLTRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SS71</accession>
    <name>A0A3R7SS71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DnaJ-like protein subfamily C member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_008963</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002125">
        <property type="protein sequence ID" value="ROT72657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SS71"/>
    <dbReference type="STRING" id="6689.A0A3R7SS71"/>
    <dbReference type="OrthoDB" id="1726119at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000224">
        <property type="entry name" value="DnaJ and TPR domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051727">
        <property type="entry name" value="DnaJ_C3_Co-chaperones"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44140:SF2">
        <property type="entry name" value="LD25575P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="196"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="366"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="478" mass="54624" checksum="E3B1F81D965E5DCD" modified="2019-04-10" version="1">MHILEVESTSAAEVDRHLQMGVQMLAKGQLHDALSHFHAAIDGDPTNYLSYYRRATVYLALGRARPGLQDLDEVIKLKPDFTAARAQRGGVLVKLGRLEEAHIDLEHVLRKDQNHEEANKLYVTIEPLKKEILEAYSSVRTGRYQHAILLLKNIIERCPWDASLRELRVEAYQAVGDVASAIADLRVTTKLIQDNTSGFLKLATLYYQTGDVEQGLNEIRECLKLDPDHKECFTFYKKVKKVNKLVTNAQEFANEKKYEDCTATASKILREEKEYEEVRFLAYDKLCQCQSRTDSEAAVEACQRAIDIKEEARLYCDMAEALLLEEKYDEALNSYQKALNIDEGLQRAKEGVDKVQKLKKQASKRDYYKILGVKRTAGKDEIKKAYRSLAQKWHPDHYEGKEKEKAEKMFIDIAAAKEVLTDEEMRKKFDQGEDPLDPEQQQQGQGGQGFNPFQHFHFQHGGFPGGGFHGGGFKFHFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWV4</accession>
    <name>A0A3R7SWV4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001292">
        <property type="protein sequence ID" value="ROT79095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWV4"/>
    <dbReference type="OrthoDB" id="6344432at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="77"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="42778" checksum="20F3C3A14522498B" modified="2019-04-10" version="1">MATPACKEEISKEWLQVILTQYESRSKPKTSVAVTSFEVNPGVGPGENFSSQLLKIVVETQVSHGDQEEHTAKTYNLLAKFMQGNGFIREMGKTTNAPLKEIMIYSDVIPALNQFQSERGDGSNQVDIPGFVHGVCVEEKVKYNEKTLEKLRTNRAAVKRRIKSLLLPQNQKIKCLCHGDYWNNNFMFRSDRADGLSDPDAIMLVDWGNTQWYTPVLDLQYLIHTSTQLDFRREHREEILQHYHSVFTAVTTKLGAPVPSWTFNVFKEECQKARIFGVVMGMTVNLITLSKQNQTGPLVQTKPVNSSSLGWRISCRLGKIMAPLFLSKMMQPLTRAFLSKWMEPNFNELTTGKNEILNQRFYDLLVEADADGVFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SX44</accession>
    <name>A0A3R7SX44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001241">
        <property type="protein sequence ID" value="ROT79459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SX44"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="45296" checksum="8337F8488DE61E2E" modified="2019-04-10" version="1">MATTEISCLDCVVQTDTRTKPCATVSDRLPGRLSFGWLGRVRVRSKLAKGSIYLSRLPSPPFSPIPACLPLVSLSPPSPARPFVLSLPTSPLLPTPILFPLPHPLPSLPSPHISSLAHQSFPSPPPRIPLDSLPLSTPSLLPSATAPLSSPHPSFPPPLPPSSCPSPLPHPLPSPPSPALSRTQREDNKVNPTSSFLLCAALPPSSLSPLPLPPSSLSPLPLPPSSLSLCLSLPPLFLFALSPSSLSPLPLPPSSLSPSPTLHVSHPLFLPLQSSMSLAASPSLLSSSLFNPPCLPLPLPLSLSNPPCLPPPVPPSSPPPSPILHVSHRSLPLLFLPLPIFPSLRHLSNPPCLPSPLSPSLTNPPCLPPPLRPSLSNPPCLPPPVPPSPKPTTIFHIHYSRCNASPSPRRRHYEMLRVCFLLPKAIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9P5</accession>
    <name>A0A423S9P5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polycystic kidney disease protein 1-like 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021396</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polycystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004485">
        <property type="protein sequence ID" value="ROT60921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9P5"/>
    <dbReference type="STRING" id="6689.A0A423S9P5"/>
    <dbReference type="OrthoDB" id="444119at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050982">
        <property type="term" value="P:detection of mechanical stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051223">
        <property type="entry name" value="Polycystin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046791">
        <property type="entry name" value="Polycystin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877:SF194">
        <property type="entry name" value="LOCATION OF VULVA DEFECTIVE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877">
        <property type="entry name" value="POLYCYSTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20519">
        <property type="entry name" value="Polycystin_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="493"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin" evidence="9">
        <location>
            <begin position="334"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="8">
        <location>
            <begin position="463"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT60921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="564" mass="63522" checksum="8473CE4F65C51452" modified="2019-05-08" version="1">MTVDLLLSPSESEEGKSFTEDFYVKGHRNANEGHIWMSIFLRPTGSRFSRKERVTVCAFFLYVSMLLNAVWYKSQVESPRSGLFNFGPITISMEQTVTGIFTAIASRKQAGLPVTHDDGPVSTYDSDSVDSKNPSKDQARQVPALVDAPRGLDPAPGPHRVSVFFVWSYGVMWGETKTWIKVLIMTTIGAACCKKMDNVTEDIDCDEELPALKIDEAWKKPKPLDSSMSRKVHRVGGVDPKETDVAALASRLTKEREMGFVIRDIGAYCLFLLLLYVLVSGRTDENAFLLQDHMRNVFIKEGNMDFDFSTKVQSRETHGHASQVLFGLSRILDEEYRDYCAHWKVNATFSGACQYPEFHYQTAGELQTYPMVGYLGTYGGGGYVVRLKGAQSDITDRLLVLQKLNWIDRCTRAVMLEFSTFNANINLFATASVIAEFNEGGGIVPKWRFEPIRLLPKSGATGYIVTLSEIIFVVCTVIFTLKELWKIKKQKCSYFASYWNIAEICILITSYATVGVYVYRYLLTQEALEIFEQTYGNGYIRLDSAALMDQFICTWLPSSASSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBE1</accession>
    <name>A0A423SBE1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Caspase family p20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020688</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004127">
        <property type="protein sequence ID" value="ROT61519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBE1"/>
    <dbReference type="STRING" id="6689.A0A423SBE1"/>
    <dbReference type="OrthoDB" id="6044770at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF8">
        <property type="entry name" value="CASPASE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Caspase family p20" evidence="5">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p20" evidence="5">
        <location>
            <begin position="299"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="519" mass="59513" checksum="946A33F12E59B4DE" modified="2019-05-08" version="1">MASNETYRTRSSPRGHVLIINDLENCKKDIEDLQKIFTSLGFNVLKPCRNLKKEELKETLRNFSERPHHDSAVVIFYGAGNGNNLVSGDHLVTSFSEFTEIFNDKNCPNLAGKPKLFILNTCCTDVRSEESHNSEVDDTEVSLQQGLGELTGLSTDGNTEFEIAQSTVEISDERDMCLLIVEVDGQCKEGSLLTKALYQVLLKHACDKELMTLSKMILQMLEDLQKAKGGEQYYPEVRTMKFLHDYYFNPPKAEQNPPPPPKHSKIHLERGYFPQKRLSVKQVKQPRNTHSDYSNWSRPHGLALIISFDKYKSEELPDCSWRQYNANMMSELYNDMGYRTVIYRNPTNSEARSCIEEFSARREHSDLDSAVITILGLAKDCNTFYCGDGEPLHLSGVYSPFTDTSCLALKRKPKLFFFHMTQMQKWEISEESPRKELRDAFVVRLVSKVGANGLHPKKGLWAWRNALEEHAHDTHLECLISKAEDYLHDDACNTRVSDEHFEREPCFLTGKFFLNPKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ33</accession>
    <name>A0A423SJ33_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative polycystic kidney disease protein 1-like 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_017786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polycystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003280">
        <property type="protein sequence ID" value="ROT64278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ33"/>
    <dbReference type="OrthoDB" id="444119at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050982">
        <property type="term" value="P:detection of mechanical stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051223">
        <property type="entry name" value="Polycystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877">
        <property type="entry name" value="POLYCYSTIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10877:SF150">
        <property type="entry name" value="REJ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="8">
        <location>
            <begin position="56"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Polycystin cation channel PKD1/PKD2" evidence="8">
        <location>
            <begin position="148"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT64278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="48954" checksum="CA51A9097CCC76EC" modified="2019-05-08" version="1">MRGMIKRCSGFSNVFKEDDEAYCAHWKPPTNLTKDSPDCKIPEFKFTGIRLLPHHDSFGLFVMVCEASFVAFIIYYTFREFRQLCRNKVEYFKCYWSYAEIAIIVTSYATIAVYVASRSSSLQPHPRKRIREPPVRGFPGRTLLLPGVLTATLRQCWDDLSGFLIAFIICFCSFTGMFYLLLNSQLENFHNFVISVETCFSMMLGKFQFEEMKQASSVVPVMFFIFVLSNSWVLLNLLLTVIIRSFEQVGGHGDRVVKCNIFILTTCDHIPSTPAKTQHTYTHHIPSTPQPTHHIPSTYPQPQVNATYNHHMPHHIPSTPGHTLITRLTTYPQPQVKHDIMQQPTDYMMVSFIMGRIRGFFGMQKPPPPPPVTMATPSSPSEAPPTREEGEGKGAFNSKVGPKPRPIQLAQGIGEVRAGTQKSKRHPGFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKY1</accession>
    <name>A0A423SKY1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017176</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003173">
        <property type="protein sequence ID" value="ROT64876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKY1"/>
    <dbReference type="STRING" id="6689.A0A423SKY1"/>
    <dbReference type="OrthoDB" id="10023921at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06565">
        <property type="entry name" value="GH20_GcnA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038901">
        <property type="entry name" value="HEXDC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21040:SF8">
        <property type="entry name" value="BCDNA.GH04120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="7">
        <location>
            <begin position="219"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="644" mass="71034" checksum="E3AF0B2000EEE3C7" modified="2019-05-08" version="1">MKFEKYKTRRQAGRGGDRAGLPREDGRSDRHHSVARRPGVIPLVSASAPLRRWWSFCSCFGRLAVCTVGSDGPRIAGVKCVAWSSPICGPVLEGFVLFPAMVSCGRRRLMLALALLCVLVVLKLWLLAEPNPNASPVFVVTPRRGQGGRTHAASKELQTQTGMEVPPERLWHLDLKGGAPLVPFIEGMMSLAARAGATGVLLEWEDMFPFTSPLAELSAHNAYSLKDVARIMQAAKGAGLSVIHLVQSLGHMEYALKQQKWADLREGESPGEACPTNPGTARLVLEAVDQIMTAAPSPFLHIGADEVFTLGQCQRCRSKGVAPLQLYVDHVAQVARSAKARWDVKVLIWDDMLRHASSTLLHSLAGLVEPVVWAYGPDVTRMVPPYILRAYAAVFPRVWLAPAFKGATSPRSVMPNIARHAANTLAWVQEGQRMRRHAGLHVAGIIITGWSRYDHFAVLCELLPSSTPSLVLTMLTASRGFLTAATLRDTHTLLQCPPHVVLDPARDPQLWAARDCDFAGANLADLIHRYVTLRDNIKLVAREAEEVGAWFTPYNIRHNFSSPSRLREATRELPSLLSTLADLYAEVRAVLPQYHNPATVEEWIEQHLLPLNQTLSRFNRSFNALMKVKAWPRRPLGGKDPPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLZ7</accession>
    <name>A0A423SLZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low-density lipoprotein receptor-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016752</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003107">
        <property type="protein sequence ID" value="ROT65275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLZ7"/>
    <dbReference type="STRING" id="6689.A0A423SLZ7"/>
    <dbReference type="OrthoDB" id="21182at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00053">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000241">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050778">
        <property type="entry name" value="Cueball_EGF_LRP_Nidogen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513:SF13">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513">
        <property type="entry name" value="VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00058">
        <property type="entry name" value="Ldl_recept_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="36"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="7">
        <location>
            <begin position="538"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="7">
        <location>
            <begin position="582"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="670" mass="74974" checksum="CB26366E5DA4DAE9" modified="2019-05-08" version="1" fragment="single">MWKCEGVQDSCINTTQVCDGNRDWPRMAQMKAQPAENNPCASNPCDHLCVLKHPQGYTCLCRPGYKLASGGKCNQEETPYLMVMKGSQIVDVALTPGEKGAAGFLTPIVGVEHGLQLDYDRNGDRIFWIEAVEEDSENGTIYTMEIGGGNRSTYLDFGIVGSPYTMAWDWVGRNMYIGNRVANNIEVLKLDGKIKYQSVILDNNGNATGVGRPKSMCLDPVDGFLYWLDDGGTGVPAKVGKVSMDGSDPVILYNFTNIRPEYITIDIEAKNLYWSTSNEAKIMTSDVYGSNIREILTEANHIAQPKALAVYESRLYYLDSSYEKVERVDLPDGLNPEMLLENESDLKSLKVFQKRPVINSHPCMVGNGGCEHICIPKINKQRTCRCTTGYKADGEKGCKPYDKFAIVSQLDIVRGFSLDGAGEAMAPIAEPGHNVLHVDYHYSKNYIYWIEFNQGGSNGIYRSRPNGTEKEGVVTTGIGSNGIRGIAIDWIANNLYFTNVFPHETYVEVSWLDGTNRMVLKSVTKDSPRELAVNPIKRYIYWIDYGQFPMIGKAYLDGTNWQPIVTSGVSNPRDITVDMFTHDVYWVDSALDSINKVSFSGGNRQFIRRKLPNPMGLALNNNFVYWIDRNLNTIFRASKYPGNTTQAERFKTNMENLRDIAILILPISPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMB1</accession>
    <name>A0A423SMB1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003089">
        <property type="protein sequence ID" value="ROT65405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMB1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="837" mass="98249" checksum="4799849564399D0A" modified="2019-05-08" version="1">MGNANKWEPTYPNPQSEAKNGNPQQYHNQNRTRTNTQPTYPQSEREQREHNTYPQSTMGTTYPIPQSETTNGTHIPNTHQNRKMEPTYPQIRTNNGNHIPTTTIDTNKWETHNHNTTIRPTMRTNGNPHTQIPTIRTRTNGNPHTPIPTIRTRTNGNPHTHNQNTNKWEPTYPHTHNQNTNKWEPTYPQYHNQTHTNKWEPTYPNTHNQKQQMGTHIMNTNKWEPTYPYPQSEHEQMGTHIPKYPQSHIRYPHQKRTNGNPHTQIPTIRTRTNGNPHTHNQNTNKWEPTYPNTHNQNANKWEPTYPNTHIRTHTQIPQSEHEQMGTHIPKYPQSEHEQMGTHIPTYPQSNKWEHIPKQQSETNKWNHIPNTTIRTRTNGTTYPIPHQNRTNGNHIPKYPQSEHEQMGHNTQMGIRTRTNGNPHTRIPPTNTTYRIINRTNGKPTIPHRIPTIRTRTNGTTYPTINRTWEPHTNTTIRNEQMGTHIPKYPQSEHEQMGTHIPKYPQSEREQMGTHIPKYPQSEHEQMGTHKYTNKWEPHTQSEREQMEPHTPIPQIEHEQMGTHIPIPQSEREQMGIPTIRTRTNQIPKYPIRTRTNGIRNKWKKSEPNKWAIPKYPQSEHEQMGTHIPTIRTRTNGNPHTRIPTIRTRTNGNPHTQIPTIRTQMGIPNQEQTHIPNPQSEREPQNGKPHTKYPQSEHNKLEPTYPQSEHEHMGPTYQIHNQNTNKWEPTYPHTHNQNTNKWGPPIIPTIRTRTNGNPHTHNQNANKWEPTYPNTHNQNANKWEPTYPNTHNQNTIWAQTYGNPHTQIPTIRTRTNGNPHTQIPTSKPRRNGQVSWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMY0</accession>
    <name>A0A423SMY0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003066">
        <property type="protein sequence ID" value="ROT65605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMY0"/>
    <dbReference type="STRING" id="6689.A0A423SMY0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="376"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="522"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="587" mass="65251" checksum="BF77177CA3A7E47E" modified="2019-05-08" version="1">MPRLRSLFLPHSLPLPLNRTSLFLSPFFPLSLTSPISLPHSPQPLTLSLSHFSPHPSLTLTIPSTSRSPSSSPSLPSLSPSSPPHYPFSSSLFRLPHYPSPAPSSPLITPPLSLTIPSFLLLFLPHNPPTLFFSVSLSPLFFPPSPSLTPSLPYYPSLSLTTPSLPHYPSLSLTTPLLPSPVSPSLLPLSPSLLPSSSLPPSPFPFLSLLSSLSHLHYPLFPHYTLLHYPHYTLSFPLSLPLLSSLSHPHYPPLPSLPPPPFPCLSPLSSLSHLHYPLFPHYTLLPSPCLSPPLLPLSPSLPPSSLTTPSSLPLSLPHHPPVPSFSRISKRTSPALLKERLTPGVKCRSWSVTPSVSRGCKWPKCSPPSFSSSCHFFFFFCFFFFSFSSLSFLFFFFFFFSFFSSSSSFFLSFLFSFFSPYSFLYIIPILLLLFSFSFLLLFFLLFFLLLLLLLTIIIIIIFLLIPLLYILLILPLSFLLPLLHPILLHVLLLLFVLFILFLLLLLLLLLSFHLLLLLSFHLLLLLFLLYLLLLLLLLLPFGLCFFLPFASLPIGKGRGPAASVPPHSLASCSPNKWSPEPGLLPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRC1</accession>
    <name>A0A423SRC1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015209</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002895">
        <property type="protein sequence ID" value="ROT66741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRC1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="256"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="535" mass="58173" checksum="76E3E029AE3F3AB5" modified="2019-05-08" version="1" fragment="single">SPLLSHPSPLLHSRPLSRSLHFSLSIFSPFLPPSTPGCLRDFLSYVSLDIPLHTLLPRLLFLSLSSILLLQFSLSPFLPIFPFTFSPLLPLCLLPLLFSLVTLLSLPLPLYHVPFSPFITYYAPSWSPPLLSSPSPLSNRPLSSPPSVLSPSFPSLTSPSLASCQTIFFPPPLLRRSFTPPSFTPPSLPLSRATLALSPPLFSVNPSFSIPLFLLFRRSCHSLPSHSFSPSLPAISILPQPASLLSPPSFHFLSSPSSPHSLSPPHSPHNHSLSSRSSPTTHLAPHSSPPHSHITNLNLSSAPPLSTPFFPFYLFLLIPPSPLLSITLPPFVSCHPPPSPSPSICHLLPPSPPSLHPPPTPPPSFHSLPSPYSPTPFLLIPPYPLLSLPPPLHLPLPLPSWPLAPTPPPVPSLPSILPPPPHSLSPFHLATPLLPFLPPSHPPSADNLPPILPRPFPSILPPSPPSPPPSADVALPLTLHRGPRWDQQLPRVVCFLSDSPPGFGFDLCVVRFLPRSSPPRPRRWPEWDENDELDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SS66</accession>
    <name>A0A423SS66_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002849">
        <property type="protein sequence ID" value="ROT67092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SS66"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="42795" checksum="7AE9EAA1EA6083FF" modified="2019-05-08" version="1">MSRHTDLRRAFIPSPIYVKPTKDATLPAQVFSKVWLTVLQFLGLFPYKRSSSGEYQVSFPLLSWSFVFGFLMLCVSGFLFRLNTSQNQAFLLSLHISYFSVVVICLAFFLHNFQWRKYGVLFSRLESLLMSRDLPRLDRPCRRKIRDLFDVKLILICVAPCWQFVEALLSVATGEGKDYGGLPFMIFYTLYFTRQCCFTLFIRRTFRVLNAPLENMELLDPWTLLDSTISVSSIWLQTLHARVVKVRCLVRGFLGVLFWPLVLLISSLLARVIVHSIFVAHSNVGTGMWRLILATWISDTIYFVILYSSTACLDSKINKTLSALEGLREFPLGGLFPLASGSLSSAASFALTYVVILVQTGYQSSAEGQTRLEKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SV41</accession>
    <name>A0A423SV41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013844</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002723">
        <property type="protein sequence ID" value="ROT68065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SV41"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF47">
        <property type="entry name" value="TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019560556" evidence="6">
        <location>
            <begin position="20"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="233" mass="26362" checksum="E26370208B00D2A3" modified="2019-05-08" version="1">MQLFFVAAVFIVTFPLSLPFTQPNSHTLRSPFTSHDCFRRVLTVLAPQLLVTFGLAAMFVRVSSFSAYAHRNPGTFGFSLSVMCAMMLALVFCCNLRKKSPDKYIMLLVVAICEAYMLGDMSSCKEDVDMAIVVTMTIKYDFSVLVVFVVVRVAVPVLFFGSVAIWSNAIVNMKYISLWLVLFSFCVVIDIQRIIGRNHILSLSPDELSVALHLPSHHPCLYVHTRDHWRTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SV42</accession>
    <name>A0A423SV42_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative galactose-3-O-sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_013797</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the galactose-3-O-sulfotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002721">
        <property type="protein sequence ID" value="ROT68082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SV42"/>
    <dbReference type="STRING" id="6689.A0A423SV42"/>
    <dbReference type="OrthoDB" id="514299at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001733">
        <property type="term" value="F:galactosylceramide sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009729">
        <property type="entry name" value="Gal-3-0_sulfotransfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14647">
        <property type="entry name" value="GALACTOSE-3-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14647:SF87">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06990">
        <property type="entry name" value="Gal-3-0_sulfotr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT68082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="41678" checksum="7950AB5A2E342DFA" modified="2019-05-08" version="1">MNNDSLSPTSVLTSVEEADPTPLEMSSTCPPQRHVMFLKTHKCGSSTVQNVLFRYGLTQNLSFALPLVGSSLKSNEKFMTSMIPESLLPPDGKVDIFAVHSRLNAEEHRRVLAEDAKWVTIVREPASLFESLYTYYGIGRWYKLDLTELTNFPMEKLRALPRFGKTLGNNQMLFDLGFDADLSEAQLRQAIEELDSLFDLVMVAERMDESLVLLRHLLCWSLHDVVVFTKNARGEGARTALDAHTRQRLREMNDADVRLYEHFLAKHRRAVLAFGARRMAREVAALRKLRDRSFEDCGVFRVEGHNPFPKFREYSGLVGAYATASEDEQCQRLVFSEEALLDEAKQRQLSLFEDVGRARQRSGPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVV6</accession>
    <name>A0A423SVV6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002692">
        <property type="protein sequence ID" value="ROT68315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVV6"/>
    <dbReference type="OrthoDB" id="8195312at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019460620" evidence="1">
        <location>
            <begin position="19"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="337" mass="37294" checksum="051277F26B04FDB9" modified="2019-05-08" version="1">MKVECAFLLLCLLSSTTATWLFPGQNRPSHPVDNAQSGSFHDTLIRNERFDVDSSGLISAYGPRTYDAGGLPLTGTRGGGGGGVDDHLFLVNNRRRYGFKIPRSLDAPIYGLRAPPTPSPIATASSSGFAKNYNLPLPSPNTPTTTLAQLNRVHGYHAPSQYIQLQPVPSPNHDYEAAQSIYSPHSFRPSPHMQSDSAFKPSAYFIQDYEAPNAYPTPAPLYKESTIPPYKHRKITTTYKPFTYPTVESYKVTTQKPYKPAPVPQYKPPTYSTYKRATPRPFKVVTPAVYSYNTPAPAKYKSYGATPSKDYLKTVTTEAPYKNKVLAYPTLANNKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWG8</accession>
    <name>A0A423SWG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002657">
        <property type="protein sequence ID" value="ROT68557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWG8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="43093" checksum="5D47CD4122CE62CB" modified="2019-05-08" version="1">MFLPFSLPSPSHLTSSSSNIHVPSSLPSLPPPLPPPSPILPPLHSKSPTHVPFLPPLLPLPHLTSSSLTPGSFLSSHSSPPPSYLLLLLTPFLPPLLAPPSPLPLVPSSPRFLHSPPSPPPRPPPSLTSLLPFPLPCPSPLLPPPLFPSLPTHPTPVISHPHNAGPSHPLPHLPHPPTSLSFPHRPTSQTYPTHPLSLHPPYSHYHRPPPLPPLNLTYPPSPLSLRPPLSFLINSPTPVLCHPPLTLLPPTQPPVLSHPPPVLFPPHPLPLLPLTCPLPPSTVLCRQPLPLSPPTTWSSPPSTPTLPHPTLPLTLNLPHSLPLPPTPPSPPLTSLTHPSPVLSPLPCLPPYLHFTPLTPCPLPPPPPTLPLPPSLRHYDKRRINLMEILPFFARRTRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2I2</accession>
    <name>A0A423T2I2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010977</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002394">
        <property type="protein sequence ID" value="ROT70729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2I2"/>
    <dbReference type="STRING" id="6689.A0A423T2I2"/>
    <dbReference type="OrthoDB" id="6357234at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="191"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="322"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="389"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="456"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="4">
        <location>
            <begin position="500"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="794" mass="87663" checksum="FE952AFC9F5271B1" modified="2019-05-08" version="1" fragment="single">LLKAASDGDLQGVRFWLSAGASVEAASSAMGEERGLRPLHLAAWAGHVGVVRELLSRDADFKARGREGYSAIHYAAKGGHIDVLRILHEKKCNMKAKTDSGQTILHVAADNGNLKAFKWIAENTDIDHNTTNNEGKTALDVAQNGRQKSIVTYLLKIPEQEAFQKGDMSKVRDLLTDGFDVNTVFQEKKKKECRPLHLAADGGHAEIVKILLQRGADKEANNYEGMTPLHLASWGGHAEVIKVLLGAGANGDARTKEGMTAVHLASMGGHVSSIEELATRCDILTSTREGKSALHLAAEYGNLGAVQWLHLQGLDVSLKDRSGQTPLQLAKDEGHKKVVEFLLRHDQQTLNRNGVELHRAVAAGNLGEVRRILDLGANLNLQSAVDGDDGRQPLHTAALLGHTDILRELLRAGADKDGRDRRGNTVVRYAAVHEDPHLLRILQMENVDVATAVNFSGETPLHIAASRGNLRVLEWLLQTGVSVKQKNAAGMTAEENEEAEGLRSPGNTGYMNTILQCLFHIKEVTNLFSSDTYKQHLAGQSIHGKVTESFAAVVRALTYGENYGGVLNDFKSSMCRHDPLFAGNDQRDAHDFLSAFLFAARKEFKNPEDSPFSDLFFGKEQAVIKCNGCKNEVLRKDEIFSSLTLTVHPNQPGNRLQTLIANAYGEQRIEWDCNRCKSKSCTRKVSVEAFPKILIIHFNRYSPNSKSIHKAFLNYPVQLTDMNDYKIKKVRRLFGGGLKYQLRSVACHRGSMTGGHYTAICKKADRWFKFSDQQVEPVQSPLVQEAHILFYEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2R7</accession>
    <name>A0A423T2R7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002385">
        <property type="protein sequence ID" value="ROT70780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2R7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="51193" checksum="3ACE3FA58DA0596F" modified="2019-05-08" version="1">MHPPPFLFSSPLSISLFSRNQLSSPLALSGSCSAPVFPSYPSSPPCLRSSSSPSSFLPLLLPLFLQSLLSSSLRSLPSSSLFLLPPLFSSYPLLAPPLPLPLPLFLLTFSQPTLSSILLSLYLMCTVLSPPFLLSLCPPLLSLLCASSPPFLAPRRPTLPSFLPLCPFSHRHDLAFYHTRLPLLGTTLSLSLPLSSFIAPVSCISLITPLTPFLLASSSVSPLPSPHRWNYAHPSPSHTLLLLSFVFLPRNLLPSLSAGLSFHIPFSYFLLLLPPHLMPLPLDLPACSPKLFTPSHPFPSLDTSPYFSTLSSYTILHSSISCTFSLVPSSHLTCFLFSPLQYFPPSFPFLSPLRVLLSSSLFLYSPLSCRTPLLFTCPPNSCSSPLLHAPSALLLSSLLDDSRSLLFLACFPLRLAFTLLYLYRDTVPLKRYFSRLSYFQTFNLLVPLLSHPHRHQRSSSLSSSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T336</accession>
    <name>A0A423T336_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002374">
        <property type="protein sequence ID" value="ROT70884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T336"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="485" mass="51987" checksum="4A85CA57D9A059FB" modified="2019-05-08" version="1" fragment="single">MPLQNLQSSMRTYVYTQVNTRIPVHLRSEHVRMSYTYVHTLTEHICRVYVCAFYTRSPQQPPCLAHLPSPLFPSPPPPTPTFSSSSSTLPYLLLSSSSLFHLPLPLSPPLSSTYPHLLLLFLHPALPSLLSFSPPALPPLPFLLSSSLPPPSPLPPPCPTSPPPPLPLLFPERVWAGGRGDVRIYGHRNMGCQFALRLNPVFPGAVLVSQTPPPPPFTSLSPPPSPASVISLPTRPPLPPLTSPPIPTPPTPSLLPKPTPPPSSPLTPFQYPPPLSVPAPPPPVDPALPPSRRPCPYPRPVAPAPPPSPSPSTIPIPPPVDTAPPSSHGPYPPHPPRRPYPLPRPSTLPLPPPVDPTPSPLPSTLPLPPIDPAPPPSRRPYPSPPSPYPLPPPSTLPPPPHTPPPGPVRCRALPRLKKSSICRVVFADLNIFPTTGQAHRGVARALRAGSESRGAKRDELRGNCEQDEPSACCELCEANGRVEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4T2</accession>
    <name>A0A423T4T2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002284">
        <property type="protein sequence ID" value="ROT71520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4T2"/>
    <dbReference type="STRING" id="6689.A0A423T4T2"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="22790" checksum="E52223EC55D0831E" modified="2019-05-08" version="1">MTTAARPTFEPAKGGMGRGERDLSALSKQYSARDLPSHTRLKYRDHGQSTTDELRSRDFRRELEDREHQIAPANLDADDPQDDDDEASDSDDSDDEAVLFAELERIRRERAEEEAKKQRERQEQEERIRMENIISGNPLLNLAAAPKSDMKVKRRWDDDVVFKNCAASEPDKSEKTFINDSLRSEFHKRFMEKYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7T4</accession>
    <name>A0A423T7T4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_009100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002141">
        <property type="protein sequence ID" value="ROT72512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7T4"/>
    <dbReference type="STRING" id="6689.A0A423T7T4"/>
    <dbReference type="OrthoDB" id="5981550at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000004">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000003">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF9">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="9">
        <location>
            <begin position="462"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="101"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT72512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="802" mass="91567" checksum="C91E188C7D5B7E02" modified="2019-05-08" version="1">MRGKGGREGEEWVRRGGERERSGGGEGQKGGGEGRATRGGSGGGRGGRGEGDRSAPENPQVYRSLFVPSLKDVENRSRFGDLTSSHSVNSGLLSAINDSSAFRVGSGSSLPPIRRQEVDSRRGSVSSRRGSATLRSARSEERLPLRQDSPSTSQRPVYPARTTRREDFMQEVRKSKETKNYTEMKKFYFDTFESYASICATFKRDPDFDGARADDPGLKMELVYTPSVVHKHFLKAVINALLQERPHLFSKDRVRALFILLQTPVFLTQSSYTVLAHVLRNITSLSNGDHQLLVNWFRTLEVPRLRMIVGFVIQFITVRQFPPPDRSLPPLSKSKWWIPTATKVLAIIYASNTSSQPPLLHYTEFYNHALDHLDLMTEYRTWQLPEKPDSFSYCQYPFILSIVAKRHILTKDAEQQMILTARRSLVAKVARHQPPQIDIFFLNINVRRNCLVEDSLKEIATKKRDLKKKLKVTFEGEPGLDMGGLTKEWFLLLIKQIFKPENKMFVYHPSKRLYWFSMGQQGSLREYNLIGVLMGLAVYNSIILDIRFPSICFRKLLSPPVVPAYEHMAVGIAKEPSLDDLSEIMPEVAHGLRELLRYEGDVEDDMCLSFQVSLEEYGQPKTFNLKENGETLPVTNENRQEFVTLYLDWILNTAIYEQFRAFYLGFHTVCASNALIMLRPEEVEMLVCGTQTIDLNELRKVTEYDGYSPEYPTIRWFWEVINEMTIAQQKRFLLFTTGSDRIPVGGMGEMSFKVSCWRGHTHMLPQAHTCFNQLVLPPYNDKATLRNKLFIALDNAEGFGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBI9</accession>
    <name>A0A423TBI9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase Mdm2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001980">
        <property type="protein sequence ID" value="ROT73849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBI9"/>
    <dbReference type="STRING" id="6689.A0A423TBI9"/>
    <dbReference type="OrthoDB" id="24526at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="339"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="506"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="586" mass="65628" checksum="8A9A1610F4CE6F54" modified="2019-05-08" version="1">MLKHYLYSKRHLFDPDDILFVNCGDDELGRTLGVSRFHYDDVKLLMAKQIRREQTRPVQNTLTQQPPDTTGVDIARAHRAVLDSDTQRAVDVCDERTSNCSAINVIKGKNETNGRTQLPGLNTCIVSSTTTAESSSRLVSESTSAAVSPVAGSSRQSSENVFGGRRRHRTRSIASYSICIPDIPDSNSDVESIYSYQGYETAFCRNTEFEESEDEAGDESELFEEYEIADDDDDVQEQDHSDDDDSVIEDVEVALIAIHTLCQDDSDFWADDSDTEDQSTDDDPELVAERWDCLSCGLRNKPFVRYCGKCWQIRKNWLPDRPKKRRRKRKPRPRKRSRLRSDSVKSEDANFLQSKETDEKQSTTSPSFISDSSQEVQDFGVLTKTLSTASTISVSASPVRSLSLDIHSSQDSGVCLSQDSFLDFSPESIMEDNKNIDKQTDTEVEETSQSGSAEEQPNTSEILNTTSASVLKAKESKEDSQSRKRKSLPAEEEEGKSSKRAKLESSSEEESEEGDVEEQAKSFYQFLQSSSGKEWLKSPDSKPFLSSAPVKEVLMEAIVANMGSGSSHMLPVCQTTTKQWFKMPNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCL6</accession>
    <name>A0A423TCL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001926">
        <property type="protein sequence ID" value="ROT74176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCL6"/>
    <dbReference type="STRING" id="6689.A0A423TCL6"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="744" mass="80287" checksum="432CFCD448B3B127" modified="2019-05-08" version="1">MGDSAVAEVTGEVVMEQASSTQTVTKRSVTSIQTTHIQSSHESSVRVESVVQGGTAEQTFAVESVVQGGSVGQSLAVESSHVEAIADIPKEEAPPVEESQPEPEPQPAEPQPVDENANAIPEEQEAQPQQEQAEEHAPEEHKAEEQEPVPAAAEEVPAEAESVPAEEPAAEASADAEISQENIKSQLHEIISEIEEQVQPEHDEVHKDEVVESQQVDVAVTPAEETPPVEEAPASEEAVEAPAQEVEEAVEAPPQEVEEVVEAPAPEVEEAPAPVVEEAPAPVVEEAPAPVVEEAPAPEVEAAVEAPAQEVVEVPAQEVEPVEEEDGVLHHTWRPKGKYELQKTAITYEDVVPIAVPEVMQEPMHNGDMSPQVLSPLEIPEGIPLLARILPKVDGEGDKKISLERLFTPATDSGDLTPKKASSRKMYSSSAFYRPDHPTIDDQVELAQRISFSLVDDNNKMSRGQSMYLKRKNRSMRWIHQGGEMQELITGSGAGGEMPEEEMQRPLEKPPMKLLMNPKGVQDFQAVQEHYENLMNAPTSPDVGKIVVQSPVIAASPSGKGAELFAKRKKRMDKFIVDETTVQKAQQQTTSEKFLKDRESSLVLVQSPWKAALETGRPDAAFDDNRLKQQLASSVVSRANVKVADAGGQEKSEPVPFAAPPMGGAPTAPAAAPASGTGAIYTAEVKVVQRASLPPTPVDIPQHSLLDLVEQDSNVNKRRSLNFNLAAKGFGTYNNFYTPVTFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEZ6</accession>
    <name>A0A423TEZ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative formin-J isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_006490</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family. Cyclin C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT75006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEZ6"/>
    <dbReference type="STRING" id="6689.A0A423TEZ6"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20538">
        <property type="entry name" value="CYCLIN_CCNT_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20539">
        <property type="entry name" value="CYCLIN_CCNT_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000004">
        <property type="entry name" value="Cyclin T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000009">
        <property type="entry name" value="cyclin-T2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21797">
        <property type="entry name" value="CycT2-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 12" id="KW-0195">Cyclin</keyword>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cyclin-like" evidence="14">
        <location>
            <begin position="70"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="284"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="572"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="348"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="505"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="702"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT75006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="789" mass="87627" checksum="5E6C58EEC1B1E0B8" modified="2019-05-08" version="1">MARKQLFGVKLDQESIGTRELPVTSRSPVLMLMAAEERWYFTKEEINNSPSRRCGIDAEKELSYRQQGANLIQDMGQRLQVNQLAINTAIVYMHRFYMYHPFTRFHRNSIAPAALFLAAKVEEQPRKLEHVIKVAYHCLFRDQPPLDTQSEAYLERAQELVVNENILLQTLGFDVAIDHPHTHVVKCCQLVRATKDLAQTSYFMATSSLHMTTMCLQYKPTVVACVCIYIVCTWSHYEIQRATEGKDWFWYVDKSVTLELLETLTAEFLAILDKCPNRLKKIMNSSQHTDDRSKSSQGGSSSSSLSSSRALNLKEYNEKREKERREREKMRDRDVVDPREGRQFTLVSTSHSSQSAPPSTVATIASSHSLHSVLPSSRGKSSKGSSGRSSHPEHAKASAVHSTNHKTHGHGTTNQGSRGDAQPPLEALRVGTADARQDQRREISARDSDRFDKSNRTSSSVVDGRLLGHETKPSRVSDSAATAPNYHNPRYHSATNGSVPPPQPTQTTPQHPSKSSSGSKRSRESERRNSERGEAELVPMVTKLEDTKYRTALSDPATPIKVRAEAQNLAMANATSKPTAATHSAPAPAVPEPVQKNPSEHVLRMKLPRPDHLKESQPDPATVLMRDRSRGGEDAGSAPIKITIAKDKVLYTPEPGSVPLRTHSTTATPVAPPINTTSANTTPSIPKFKIQKSRLKQKDLFGGTSSTSPESSPAGDLARDTPTTSLKIKISRDRLRPDKESKKRDRDRSPGDIQAAKVPRNGSEARSTHASPQVPIKDLDPSRWSSQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFI5</accession>
    <name>A0A423TFI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sui m 13 allergen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006249</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001799">
        <property type="protein sequence ID" value="ROT75222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFI5"/>
    <dbReference type="STRING" id="6689.A0A423TFI5"/>
    <dbReference type="OrthoDB" id="412780at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00742">
        <property type="entry name" value="FABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000463">
        <property type="entry name" value="Fatty_acid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031259">
        <property type="entry name" value="ILBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11955">
        <property type="entry name" value="FATTY ACID BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00178">
        <property type="entry name" value="FATTYACIDBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="134" mass="15018" checksum="1F97E12BD62731DB" modified="2019-05-08" version="1">MAQFEGKYKHDRDENFEAFLEKIGTNFVMRKMASKAKPSIEVKIEGDTWTVQVVAAVKTVTMKFKLGEETEIDTQDGKIKVIFGLEGNKLTQRPADTQNSKAVLVEREFTGEGINQKMTHLSSGAVGMRCFVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFL6</accession>
    <name>A0A423TFL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative nephrin isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001797">
        <property type="protein sequence ID" value="ROT75238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFL6"/>
    <dbReference type="OrthoDB" id="10006996at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="84"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="188"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="45984" checksum="384E48E548BFEBCA" modified="2019-05-08" version="1">MIPPPPPISIHPPSPLPPLLPPSPIPIPPPSQPPPPPPHLLYTFPLLSPLPPLLHPSPTSFTPSLPTSFPPFPPTPTSPFPPSPTPFLRPVCAPDQQWTYGGGSDRAVHVRCRVNAHPEAHTYRWAFNTSTETVYIPRNRTRKQGKNTSVMSYTPASQQDYGTLLCWGAQPGRHAGEPVRLPRHARSAPAPVHNCSVWHNASGAGEVVVACQPGWDGGLPQTFTLEVRKTSSSPSSSSGSRASPPSASLGLSLASLTEQDEPHFTVTGLSPGTEYILSVVSSNSQGAAPPTHLLHYTPIDVAEKRLSAHQRRPQRQHRVQRRRGRGQGGQGGKVYTPTPAQREHADEGGFEQLRPDLIMVKEESSEGAGGRQGVASPPSRPVSFAPVRSSFAVDESEARLDGVRSPPSPRRPVSLPGPPPPPPTRTPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI23</accession>
    <name>A0A423TI23_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001695">
        <property type="protein sequence ID" value="ROT76089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI23"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="251" mass="27009" checksum="88D41538E44E02AE" modified="2019-05-08" version="1">MATKTTAAEVLTESPCKTGLVQSRIKGGILKVKQRGFVRIKGGILKVKQRGLVRIKGGILKVKQRGLVRIKGGILKVKQRGLVRIKGGILKVKQRGLVKIKGGILKVKQRGLVRIKGGILKVKQRGLVRIKGGILKVRDPEGKATWSRQDKGRDPEGKATGSRQDKGRGPEGKATWSRQQQDKGRDPEEIQAALRQALQDIPERCGPAGALFGRESFGVRSAVSGHRGIGGHEGGNLRAAVVSGRDQGPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJE2</accession>
    <name>A0A423TJE2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001645">
        <property type="protein sequence ID" value="ROT76553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJE2"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000710">
        <property type="entry name" value="Zinc finger protein 768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="240"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="271" mass="30078" checksum="4E2DF948FE329FBB" modified="2019-05-08" version="1">MLDFFDLLDIDVSKPLFRSGDPCPQEQMREDISEFLIDFSSFQLFVSELCSEKLKSEVSDAYLKTSDLEVEDVSSVSDISLLGLGSSDVQQQWPSYPQPIHSEQPPQFHHPAPEVPVSPPGVPQYYPSPALNSYAPAAAPMQQNIEIKIPQFASEAPQPSPHLPHQYAANYYVVALPPPPNAGQIPFSGAQTGVYWQAMAPAPPSRNRRKPRVCSVCNKTCKNPYELKLHMNSHTGAKPYVCKVCGAAYSHYSSLSTHRRDKGHVKRALEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TME2</accession>
    <name>A0A423TME2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carbonic anhydrase</fullName>
            <ecNumber evidence="2">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001500">
        <property type="protein sequence ID" value="ROT77644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TME2"/>
    <dbReference type="STRING" id="6689.A0A423TME2"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF265">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="130" mass="14624" checksum="2CBD95B890B4760D" modified="2019-05-08" version="1">MTYRFNVVLSLSESLAAGGAQWGYTGEHGTAHWGSIFRSCSGQRQSPINIETSNVNVEYWRPFILKNYDQPPTRMRIKNNGHSAQVEMDAQAAPRVRDGGLKGEYIFAQFHFHWGHDSSLGSEHTIDGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN84</accession>
    <name>A0A423TN84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrogen fixation protein nifu</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001457">
        <property type="protein sequence ID" value="ROT77921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN84"/>
    <dbReference type="STRING" id="6689.A0A423TN84"/>
    <dbReference type="OrthoDB" id="1925777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1010.10:FF:000001">
        <property type="entry name" value="Iron-sulfur cluster assembly scaffold protein IscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISCU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU N-terminal" evidence="3">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="17345" checksum="43EEEDA6575A783E" modified="2019-05-08" version="1">MALLRSISRSLPLLTGRSVSVTSSAKYHKKVIDHYENPRNVGSLDKNDSTVGTGLVGAPACGDVMKLQVKVDENGKIIDAKFKTFGCGSAIASSSLATEWVKGKTMDEALKIKNVDIAKELKLPPVKLHCSMLAEDAIKAALSDYKVKQSTKEKVAKENVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNF5</accession>
    <name>A0A423TNF5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001453">
        <property type="protein sequence ID" value="ROT77968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNF5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019555045" evidence="1">
        <location>
            <begin position="16"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="41595" checksum="5E2E707B15AA092F" modified="2019-05-08" version="1">MIILLFFLSPSRSSSFPSISLLNIFFSLFSTSPPPPPLSLLLLSFLSSSSSFFSIPRLSLLFSPFPLDPLLVILFHFLSLSPPSLPLYHIFPLHPLLSLTLSSSPCFSSPFPSSIFYSSPFPFPLLSSPLSSLAFSLPLSSYLPPSLLLLSPLPPFPLSPPSLLHPSSSPLFLFSPRTQSSCSPILYFISFCFSLSFSSSFPILPGFLFISLPSHPPPPSLPHPSSSPFSPQTQSCSPVTCFVSPFISLSFSFPFLPLLLLLTSTPHSLPIVTTNAIILQTCHLRCLLVFLPLPRNPGVLSSHSVSSRPLSPSHPAVLSSLSPPVPPLPRNPGVLSSHSVSSRPPLSLAFLHRRCSPGGRNHFARSVPPKSSLFFGLREKTLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNW3</accession>
    <name>A0A423TNW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 1-phosphatidylinositol 3-phosphate 5-kinase isoform 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001427">
        <property type="protein sequence ID" value="ROT78122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNW3"/>
    <dbReference type="STRING" id="6689.A0A423TNW3"/>
    <dbReference type="OrthoDB" id="158357at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052810">
        <property type="term" value="F:1-phosphatidylinositol-5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032438">
        <property type="term" value="P:melanosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090385">
        <property type="term" value="P:phagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903426">
        <property type="term" value="P:regulation of reactive oxygen species biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043548">
        <property type="entry name" value="PIKfyve"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46715">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46715:SF1">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="203" mass="21467" checksum="1E59C6EE9FD9E3C1" modified="2019-05-08" version="1" fragment="single">ASAVAIGQALLEAGYVVCISQLEQVCVDDYVLYRPMRPSTGGSEQTTQEGLNRAQDGGQEDLWVKQINLMAESIEGEVDSNGSSKVHKEAPAHTVDTPTSITSSISNNCLDLNVKDSVVSMRKPPHISRHGSPESDQVDAQSPGMTSTSGPVLYSTTVSAVLSANAQLPFTGDTMNLTAVMSDEVLQALRGHDSSQPYARSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQ20</accession>
    <name>A0A423TQ20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001361">
        <property type="protein sequence ID" value="ROT78571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQ20"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="16881" checksum="7EEA19BD5FCFD2A2" modified="2019-05-08" version="1">MSQRAIYSVSCLRTSPRLVTIVARSGPPEGACPCSTTPPSRETAIAFFDLKQRLILRHFLKKHGTESGLPRLETLGIRTLKEAVYMVDAFPLEFNDDKDDSLNSLLQRLPRDKKEMEVLSDELWSEIASLYNLPSSRGWGIAYGKYQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQT8</accession>
    <name>A0A423TQT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Glycine receptor subunit alpha-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002487</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001330">
        <property type="protein sequence ID" value="ROT78801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQT8"/>
    <dbReference type="OrthoDB" id="6345155at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="657"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="689"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="768"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="12">
        <location>
            <begin position="413"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="44"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="381"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT78801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="789" mass="88655" checksum="BE0FA78D7027772A" modified="2019-05-08" version="1">MGVVLRVKNSTGGDTREYFFEVKFPPEQWRLLCLQHDGGSGKSRCLADDEEMPLSSKRVPGVGEGHNPPDEGSTAQEDKTASHPNSCALNNTLEGDSCQDTREKSEATTGKLCVGGFGRGKLRASVSRLRWWNRIMPDIGKAVECAGRAQGIPDWVMNEDWAVVGDASFQPHSLQEVCSSYPRYVLLQPAGTYSHSQSLCHALAGTLVSTDDLSAINTTSLQFSNICADSGEPLTWLNVKNGTRVEITPGDECPAWDSSGEKLVACVRRLQCSICKSSPTSMYTLYGHTGRFFDYTYYTDSNLSVPIFQSKGSSQIKLEDSIWVLRSNLHRVEWRLEGAALPIGRRRWRAGSQEVLLTLTKCLTTQFTCDDGQCISQILRCDDILHCRDMSDEVNCRVVEKPSRYDVSSPPPLRPWENGTVPLAYHIDVYHLSDITAINATASMDVGITLTWYDPRLKFRNLKPDIKNYFPCELVWTPAVQAVTGHGDGTVLDTNDYEKFCYAYNNDATEKRPLADPYMGHVADGMNTAVEVYLGVLATVPCQFRLQLYPFDTQLCNLSFILTNSPWSRVFDKALPGNYVPYLNARRSLLEYVLEDQTTEVGWLMQAADNNTYFVLSYHLRRLYGYHVMNSYFPTLLMFVISYATFYFQLDDFTNRIMISLTAQLVLAALFSSTTQSSVKTPYLKLIDVWYAVIITSCFLIIVLQTLINVIFHSNRLPGFVYKMACLPGPLSDIKKVVPLFTKRSQELTQREPASNTVARRYNAMARVFTLSLVSTFVVLYILLALRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRR0</accession>
    <name>A0A423TRR0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_002139</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRR0"/>
    <dbReference type="STRING" id="6689.A0A423TRR0"/>
    <dbReference type="OrthoDB" id="6275030at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070530">
        <property type="term" value="F:K63-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030177">
        <property type="term" value="P:positive regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071947">
        <property type="term" value="P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035523">
        <property type="term" value="P:protein K29-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990168">
        <property type="term" value="P:protein K33-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF28">
        <property type="entry name" value="UBIQUITIN THIOESTERASE ZRANB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OTU" evidence="11">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="274" mass="31030" checksum="43B1F3332ED7867E" modified="2019-05-08" version="1">MDSEINLFIRENSDKKEALAEDSCLQSPDAAFGGATLGFRLKFYPRWKEYERWQARLLDYYVPEGQVLEEWAELICLASQPGAALEQLHIFVLAHILRRPVIVYGVKCVKSFRGEDLGFARFEGVYLPLLWEPSFCWKSPIALGYTRGHFCALVPMEPDSPENMGAGAILDAGESQVVFLPLMTQDAKLLPVHFLTQAEVGCEETLLRQWLEVCVSEGGVLVAQQHLTKKPLTVAQMTEEWLNHYRRLAQMECAPYHRPITSQGYSSDGDSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUG7</accession>
    <name>A0A423TUG7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001152">
        <property type="protein sequence ID" value="ROT80105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUG7"/>
    <dbReference type="OrthoDB" id="6083863at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032222">
        <property type="term" value="P:regulation of synaptic transmission, cholinergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030431">
        <property type="term" value="P:sleep"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031424">
        <property type="entry name" value="QVR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050975">
        <property type="entry name" value="Sleep_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045860">
        <property type="entry name" value="Snake_toxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562">
        <property type="entry name" value="ATILLA, ISOFORM B-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562:SF2">
        <property type="entry name" value="PROTEIN QUIVER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17064">
        <property type="entry name" value="QVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57302">
        <property type="entry name" value="Snake toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="13149" checksum="1BC95B282B3C194F" modified="2019-05-08" version="1">MCWDCNSALDPRCGEFNFDKHTLDTVNCSHVYNEYLRKKEPLYCRKIVQTIQDTVRTVRGCGWLEETKADVGGCYVRTGTKDVMVKYCHCQGDECNGGASLVASLGLATGLLALTKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUY1</accession>
    <name>A0A423TUY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001137">
        <property type="protein sequence ID" value="ROT80267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="576"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="609"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="678"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="703"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="762"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1369" mass="145457" checksum="BEB397C7CACA13CD" modified="2019-05-08" version="1">MSNLSVSRRSSLSLSQSLFLLSQSLFSSRFLLSLSRSSLSCLSVALSPVSVTLSLSLSLSVTLSPVSQSLFLLSLVSFSVSQSSPLSPVSQSLFSPVSQSSVSQSLFLLSLSRSFSCLSVALSPVSQSLFLCLSVSFSVLSRSSCLSRSFSCLSRSFPLSRLLCLSPLVSLSRSFSVSVALSPVSLSVSQSLFLLSLSRSFSCLSSLSVALFCLQSCLSVTLSPVSQSLSPVSRLLSLQSLSRSFSSQSLSLLSCLSVSQSLSSSVSQSPVSQSLFLLSLSRSFSSLSLLSLLLSQSLFLLSLSRSFSVSQSLFLRLSSLFSPSSSLSRSFSLSSLTLLSLVSQSCLSVTPVSLLSLSRSFSCLSVALSPVSQSLFLLSLSRSFSCLSVTLSPVSQSLFLLSLALFRVTQSLFLLSLSRSFSCLSVLLCLSVSVALLLSLQSLFLLSLSFLLSQFLLSLSRSFSQSLSRFLLSLSRSSLFLSALLLSLSHSFSCLSVALFSCLSQSLSPLMSLSHSFSCLSVTLSPVSQSLFLLSLSRSFSCLSLSHSFSCLSVALFVSLSFSLSRSLSRPVSQSLFLLSLSRLSCLFSCLSVALLLSLSRSFSCLSVALLLSLSRSFSCLSVALFLCLSVALSPVSQSLFLLSLSRSFSCLSVALSPVSQSLFLLSLSRSLLSLSQSLFLLSLSLSVSFSCLSLSLTVSQSLFLLSLSLSLSPVSQSLFLLSLSRSSPVSQSLSFSCLSLSCLSVALSPVSQSLFLLSLSRSFSCLSVTVLVCLSLSVALSPVSQSLFLLSLSRSFLLSLSRSFSSLSRLTLSPVSHSFSLFLLSLSRSCLSVSVALLSLSVSQSVSQSVSSRSPVFSRSFSVSLVSQSLFLLSLSRSFSCLSVALSPVSQSVSSVISCLFLCLSVAFSQSLSLSLSRSFSVSQSLFLLSLSRSSPVSQSLFLLSLQCLSQSLFLLSLSRSFSCLSVMSLSHCLSSLSRSLSLSLFSPVSRSFSCLSVALSPVSRRSFSCLSVALSSCLSRSPQSLFLLSLQSLFLLSQSLFLLSLSRSFLLSLTVSQSLFLLSSLSPVSQSLFLLSLSRSFSVSQSLFSPVSQSLFLLVCLSVALSPVSQSLSLSPVSQSLFLLSLSRSFSCLSVTLSPVSQSLFLLSLSRSLSVALSPVSQSLFLLSLSRSFFLSLSRSPVSQSLFLLSLSRSLLSVVSQSLFLLSLSRSFSCLSVALSPVSQSLFLLSLSRSFSCLSVALCLSVALSPVSQSLFLLSLSRSFSCLSVALLSLSVSLSLSRSFSCLSVTLSPVSQSLFLLSLSRSFSCLSVALSPVSQSLFLLSLSRSFSCLSVALSPVSQSLFLLSLSRSFSCLSLFFVSLSRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY87</accession>
    <name>A0A423TY87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000977">
        <property type="protein sequence ID" value="ROT81409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY87"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="43830" checksum="65D7511A41A8B3F2" modified="2019-05-08" version="1">MLTLVVSGNKGVFPLRLLGTAGDSLGLTAVVFRPPFSHLRLAARVPGAAPRLPVSLLACLPVSLLLVFLCLFSVPPCLPVSLFSRRPASLPPCLPSLPVSLCLFSLLPCLTVSLRPSFLSPFFLAYLSPCVSFPCLPVSLFLVSLCLFSVPPCVPVFASPCLFAFLSSFPPYSLCLFPSLSPCFLSPCVSFPCFLASLSPLLRVALLLCLPVFLPSLSPCFLFLVFLCLFFPVSLSPLLFVYCYLSYYHPVSFPQQFFSSFLCLFVSYLCFFPLLSPFLVSLPPFFLSPVYLLFSHPPYFSFANPFSLSPFLLSSPSLLFFPYSPITSLASISVLLLLFISFFLSISSLWHLLFFLFPLPPFPALPSLLLLFLSTILFSFSSNHLFPPPSLSSSPFHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZR7</accession>
    <name>A0A423TZR7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Paramyosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_024911</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000904">
        <property type="protein sequence ID" value="ROT81924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZR7"/>
    <dbReference type="STRING" id="6689.A0A423TZR7"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000008">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000025">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000009">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="12" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="10" id="KW-0518">Myosin</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="16">
        <location>
            <begin position="7"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="38"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT81924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="699" mass="80409" checksum="F96EC4E691801037" modified="2019-05-08" version="1">MAACDEDKNAAAVCLEAVKLPEENYRLGNTKAAGEKTIKQLQHQSNELHSKLDEANRTLNDFDASKKKLAVENSDLLRQLEEAESQIGQLSKIKLSLSNQLEDTRKLADDESRERATLLGKFRNLEHDIDGLREQLDEESEGKANLQRQLSKVNTEAQMWRAKYESEGIARVEELEASRMKLAARLEEAEGQIEQLNVKNMNLEKAKQRINTELEDMQIQCERAQALADAAEKKQKNFDRIISEWKMKVDDLAAELEASQKECRNYSTELFRIKAAYEENLEQLDSVRRENKNLADEIKDLMDQIGEGGRSLHEVQKNARRLEIEKEELQAALEEAEAALEQEENKVLRAQLELSQVRQEIDRRIQEKEEEFENTRKCHQRAIDSMQASLEAEAKGKAEALRMKKKLESDINELEIALDHSNKANADLQKQIKKIQGDMRDVQTRLEEEQRLSSEYRDQYCIAERRANALHGELEESRTLLEQSDRGRRQAEAELAEAHEAVNDLTAQNGSLTASKRKLESDLQTMQADLDEMLNEAKNSEEKAKKAMVDAARLADELRAEQEHAQNQEKMRKALEVSVKELQTRLEDVENNAIKASKKAVAKLESRVSELESNLDTESRRHADAQKNLRKCERRIKELSFQSEEDKKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKVQQELEEVTSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZY6</accession>
    <name>A0A423TZY6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000894">
        <property type="protein sequence ID" value="ROT82027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZY6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21018" checksum="7F7611183C0C4078" modified="2019-05-08" version="1">MNDRTDRAESIVSWEYDEVTDVSEGSQSQAEPQSYHLQYKVADTTALLSNRSVESQITSLSGSLKDSPAKESEPPITKMDPAEIAAMSENDFEPELEEKGGEATQSASHDGQLDPPSTSDGGGTSGGGGEEVSELNGEEDQVEDLDEKDTEYLPGPSHAPPPPHLAPTSPHHQGHPMFQIGDETDEDGNADPPVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U088</accession>
    <name>A0A423U088_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-Fucosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024716</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
            <location evidence="3">Golgi stack membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01000882">
        <property type="protein sequence ID" value="ROT82129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U088"/>
    <dbReference type="STRING" id="6689.A0A423U088"/>
    <dbReference type="OrthoDB" id="10010525at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008107">
        <property type="term" value="F:galactoside 2-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002516">
        <property type="entry name" value="Glyco_trans_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11927">
        <property type="entry name" value="GALACTOSIDE 2-L-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11927:SF9">
        <property type="entry name" value="L-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01531">
        <property type="entry name" value="Glyco_transf_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="36021" checksum="F4015C48A89C29B5" modified="2019-05-08" version="1">MTRPGMAEARPDTPKKYTCACGLSQEDRKSKFSDYLYKSDVLEMFGETHALCTPAILFTSSSNGRLGNNMGEYATLWGLGRTFNVSVLLHPVMERRLRRIFPGLSMERLPASCASGWTKLDKTYKFPKNQDLFDSAAAGLLGPGKFMLGDNPVKVHLFHPFREDLLRELTFSPGLRKQARDILTKVKSKVKNQPPEITFVGVHIRRTDYINYIKKYNTTIPGKDYYTSEQWNITAKIQSPRLHHGCQMILRNRELDMATLASCNHSIISVGSFSFWCGYLSGGEVVYPKKTYSMKYLLNPDYVEKNHLDFFTPIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0D8</accession>
    <name>A0A423U0D8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Importin-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000873">
        <property type="protein sequence ID" value="ROT82166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0D8"/>
    <dbReference type="STRING" id="6689.A0A423U0D8"/>
    <dbReference type="OrthoDB" id="431626at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000459">
        <property type="entry name" value="ARM repeat superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056840">
        <property type="entry name" value="HEAT_IPO9_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058669">
        <property type="entry name" value="TPR_IPO7/11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF9">
        <property type="entry name" value="IMPORTIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25018">
        <property type="entry name" value="HEAT_IPO9_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25758">
        <property type="entry name" value="TPR_IPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="922"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="925"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="967"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1026" mass="112626" checksum="49C7F70EFAB683AB" modified="2019-05-08" version="1">MAGAEVSNGLREALIENLNNILSPQADVRRAAEEQIHVLEVTEEFGVHLVELTLDRNGPLPIRQLASVLLKQYVEAHWCTDSEKFRVPECPEYAKAKIKELLPHGLHEPISKVRSSVAYAISAIAHWDWPENWCGLFDLLMAALKTGEEAPVHGAMRVLTEFSRDLTDQHIPQVAPVILPEMYRIFCEEEKYGIRTRGRAVEIFSTLANLICMMGEYNRSLAKTLLYPTLPAFTQALVKGLQTMDGFTSDSGLKKEILSALTVLMKNVPKQMGQYLGEVLGPVWQTLTSSADTYVNTTVNAREDADDPVDSDGEVLGFENLVFTIFEFVHALVETTKHKQMVKQGIADLIYYILLYMQITEDQIENWSNNPDAFVEDEDEDSFAYSVRISAQDLLLALCQELAEDCGQGLVVAVGRHLERATTQRSAGDPAWWKTHEAVMLALGSVRDLILDQVAKGQLQFDLTNFIQSVVLADLDPNSSPFLAGRALWCGSRFGQAITPEMLEQFLQATVSALKDSPNPIIKVSGVRAVWGFCEFLKGSGNPGALQPYLPAILDGLVTLATQASSEVLSLILETCCIVVSVDSNFTAANVGRISTLCLAVFIKANNDPVLVALVQDVVRELCQNPGCTTTLQTKFIPTLASILNASTDKVPPGMQAVALDMLEVMVRSSSPPLGEPLINVAFPAVVQRTLNTDDNSTLQNGGECLRAYISVAPDQVLAYHDAEGRSGLQYVVQVASQLLSPATSEHTATFVGRLITVLIRRAGDHLGDNLDLLLRAVLSKLQGAESLTVVQNLVLVYAQLVHSQLDGVLNFLAGVPGPSGQSALHFVLTQWCSKQHLFFGAYEGKVSAVALAKLLEHGVTSNDTRLQDIIVQGDQVFSPEGRVRTRSQRVVRPEQWTQVPVLIKIFKLLINELANAIDSNLTKDDDEQESEDECWEDDEEDGQTNGDSALATMFPPASGYPSYDADTVDDEDDPDAVSDPLYSLDLQQYLTTFISTFAQHPAFPVFIPHLNPHEREVLQGIGVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0L6</accession>
    <name>A0A423U0L6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative insulin-like peptide receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024591</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000854">
        <property type="protein sequence ID" value="ROT82245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0L6"/>
    <dbReference type="STRING" id="6689.A0A423U0L6"/>
    <dbReference type="OrthoDB" id="6364276at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000494">
        <property type="entry name" value="Rcpt_L-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01030">
        <property type="entry name" value="Recep_L_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Receptor L-domain" evidence="2">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="318" mass="34985" checksum="3C3890BB2EE6B4A3" modified="2019-05-08" version="1">MTRVALARSYSLVILDNPHLRALWNWTGRGRRLAVERGKMFVHSNPRLCFHHIEALVNATNMTGLSETDVSSTYNGDKVPCKVTPLEARVTPHLYGTLLVEVATSARLPPDAVYYVNYKKAEKNVSLYEGDGPCSDQGWSTTEVGPGNGTALARRRDLIIVNLEPFTRYAVYVKAYSLAASGKGAQSDVLYAVTRPYHPTEPVGLEWVSRNRSTVALEWRPPRRPNGRVAHYLVSLQLLPDTPRIPPDLNFCRPETREYIDGKMLALAEAEKVSLARRKTPAAKEDVRDEGAKGGPEGGEESCQAPPTPPAAPAGTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2R2</accession>
    <name>A0A423U2R2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 40S ribosomal protein S5 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023907</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000759">
        <property type="protein sequence ID" value="ROT82922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2R2"/>
    <dbReference type="STRING" id="6689.A0A423U2R2"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="15"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="176" mass="19919" checksum="546BEC3A0D7B0EE0" modified="2019-05-08" version="1">MSLQDYIAVKKYYAKYLPHSAGRYAAKRFRKAQCPIVERLTNSLMMHGRNNGKKLMAVRIVKHSFEIIHLLTGESGVVNAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLTTGAREASFRNIKTIAECLADELINAAKDSKFHLLRIINSYAIKKKDELERVAKSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4A8</accession>
    <name>A0A423U4A8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000675">
        <property type="protein sequence ID" value="ROT83512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4A8"/>
    <dbReference type="OrthoDB" id="6372687at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="162" mass="17901" checksum="BDA315AE2FE4FBF5" modified="2019-05-08" version="1">MLRLKTDPPARAEWLVCSPCWEGDACEHYADYYSPRFLVHATTVVLRANSTGIVYRSWSTDEDLGLTCPLGPGNSARCPCAAVAYQLFAPPGDHHFQLDAVTGFLTRNTSMSLEDGKTYTYKIMVQSEDESHCVGGTSPSTRFSSPRIDPGSSLLESFVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAG1</accession>
    <name>A0A423UAG1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000207">
        <property type="protein sequence ID" value="ROT85704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAG1"/>
    <dbReference type="STRING" id="6689.A0A423UAG1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="45542" checksum="FA78B7A1D30A403B" modified="2019-05-08" version="1">MIPLSPPPFPYRLHPTSGPRKIPSVSTIPPPLRHPNPPPPPPHPPSSATHPPSATLPPPANPSPSSSAPIPPTLLRHTTPSPSLRHHIPSSPSSATHPPSLPSSAHSDPPFPLPSFRTTIPPSFFPPPHPALPIFLRTPQSRLSSANPIPHIPSSANPILPLPSSASHMFPPPPATHPSPLSIAILANPIPPFRHIIPPLFTGHHDPPPLGYRPTTHPPASLPPRHPSPLSTYTLTIPPSPPHATHPLPSSAHHRPDSPPPSTHSLPSYRTPIPRLHSLRHRHPRSSPIRHYPSPSTAPPPPHAPSSAPIPLLRHSSPPSFNCLLRHTEPLFRHPIPAPSHASPSSSSHPLPPPLLTHPTQSHAQALPSSDHPSAPACSRHPSPLPPPLSDHPPPFLTPPMPPLRQHPFPPSSATHIPPSSPPLRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB95</accession>
    <name>A0A423UB95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative low-density lipoprotein receptor isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_002522</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000134">
        <property type="protein sequence ID" value="ROT85971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB95"/>
    <dbReference type="STRING" id="6689.A0A423UB95"/>
    <dbReference type="OrthoDB" id="10047962at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019420600" evidence="10">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT85971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12825" checksum="D59FE66F44A0AE08" modified="2019-05-08" version="1" fragment="single">YCARGLFRCLGLPNLCLYSEFLCDGVVNCMFGDDEDDDFCSTRECLVTDFRCESGQCIKKHQECDGKTDCWDGTDEHCASDSDCPTPRTHHCGGACINPLFMCDNILDCPNAEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBE7</accession>
    <name>A0A423UBE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000029">
        <property type="protein sequence ID" value="ROT86042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT86042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="11540" checksum="8E000962921DE540" modified="2019-05-08" version="1">MDPDTMTHTTTDTVMNSTTDPDTIMDSTTDPGTIMDSTTDPDTVMDSTTDSDTVTDSTTDPDTIMDSTTDPDSVMDSTTDPDTITHMAMTAYTATQRSLVIQAIKGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTR4</accession>
    <name>A0A3R7LTR4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tensin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_017922</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PTEN phosphatase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003312">
        <property type="protein sequence ID" value="ROT64149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTR4"/>
    <dbReference type="STRING" id="6689.A0A3R7LTR4"/>
    <dbReference type="OrthoDB" id="6273691at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005925">
        <property type="term" value="C:focal adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01213">
        <property type="entry name" value="PTB_tensin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09927">
        <property type="entry name" value="SH2_Tensin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000002">
        <property type="entry name" value="Tensin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013625">
        <property type="entry name" value="PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035012">
        <property type="entry name" value="Tensin-like_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033929">
        <property type="entry name" value="Tensin_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051484">
        <property type="entry name" value="Tensin_PTEN_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45734:SF10">
        <property type="entry name" value="BLISTERY, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45734">
        <property type="entry name" value="TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08416">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0727">SH2 domain</keyword>
    <feature type="domain" description="SH2" evidence="10">
        <location>
            <begin position="62"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT64149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="37110" checksum="701F04BC14CAB4C8" modified="2019-04-10" version="1">MGVRSPSPATSQTLRQELNGHSSPAPSLYHSQSRRSSLTSLNESSEVISSHPKFVKDISKFWYKPTITRDEAISMLKDKAPGTFVVRDSNSFPGAFGLALKVSTPPPNVTSKSSDPASELVRHFLIEPTSRGVRLKGCANEPVFGSLSALVYQHSITALALPCRLVLPERDPAGAPDSVDSSVSTSGSSSSTSQLLQQGAACNVMYLHTADTESLTGPQAVKRAVSLMLAAKITPTVVHFKVSAQGITLTDNERKLFFRRHYPVNTISHCGLDPDDRRWAQKNEEGVPVGSHRVFGFVAKKGASRTENQCHILAELEPEQPATAICNFVTKVMMTSVSRPNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWP0</accession>
    <name>A0A3R7LWP0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative endothelin-converting enzyme 2-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_020967</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004264">
        <property type="protein sequence ID" value="ROT61264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWP0"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF133">
        <property type="entry name" value="PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="4">
        <location>
            <begin position="205"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="4">
        <location>
            <begin position="439"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="620" mass="69687" checksum="687407733CF7DCA0" modified="2019-04-10" version="1">MREGPDAPADGPGLASSSRVTQRQGPRAGPADSRLPKLNHIYTTFRELARSQVKANGTTPGHAPSPTVCEAGGGGAEDMHKPKRTWTERWVMGVSVAGVVVSGLVLIIVLFPLLTRKTVPTPAPTASSPTSPPTFVRLQPDSTNEDSISPGERIVLADRDVFLEGRKSSGLPQEFDAGPNTSQIRKFYKLMADNIKGSMNRSSDPCQDFYEYACGNWHQHVPPPQGVSRWSNFEAMTITIWELMEDQLKRAASSEIGGTSQDISFSEEFKDPLGRARQDLLEDADPFMLELAGRYYAACENETQLATLGAGPLQEVLRIMDEQYRSLLQKVKPLEAFQRMLEYVHHDLAVHAFFSWKVEVDNSVADSMAIEISAPSLDLIPQDLLKIVGTFEGRDVCCSEVEDILAMLIKVYQPLIFLWSTIPPARTGAGKERILSLVQDYLAVLSTNILEEISQEGSARRLYAFLRWQVAQNYAQYLHKSARNTILPLFDGITGENTTSLPHFRYRPCIKELEERLALPIAYLLMEIIKGQLHKQHDIKDMVNKVTHMAENIRDEYKRFISSFKWLKDKDKNMLVEKLNNVKILVGYPPVLDNVLQLRSLFKELHFTHDNLLQNQINLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LX86</accession>
    <name>A0A3R7LX86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003064">
        <property type="protein sequence ID" value="ROT65635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LX86"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="514" mass="54773" checksum="040C5D478536B24E" modified="2019-04-10" version="1" fragment="single">ILQDAETHGRGLTLRRHTRSRARAGCRGRVSPPSCTLPAGWRRQDQKGAWPVCPVSVREARSRPGESGGNGFVGQLVGSSAGRFRPVRQGAGRGREGVRGGEGKDRAEEGKGEGEGGEWRRGEGRGSAVEGRGWGGGRGSWAEEGVGAVGGARRGREGGQGVEEGKGGGQGWRREGRGWQGWRLEEVEGGRRVVYKSYRFIITCSSPPPPSSLDSPSFSPPALSFPFSPPSLSSLPSTSSLPSLSPSFPYFPFPPLSSPLFPLLPSPFFLPSPFPLFSPLPFPPLSPSSLPPLSPLLLFSLSPFLSPLLPFPFLPSSFPLFLPSSLPLFSPLLPSPLSPLLSLHLLSLSSFHLFFSPPPFPLFLPSSLPLFSPPPPPLYAISPPTSPSLFLLLLLPLPLFLLLLLPPPFLLPPLFLLLPFPSSSPSPFSPPSSLLLPSSSSPPPPLTPFPSLFPPPLPPSSPLSLSNLSPPPPPPSLFLLFPSSLSTSSPFPLPSSHNLLLFLLLPALSYPKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1R9</accession>
    <name>A0A3R7M1R9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dipeptidase</fullName>
            <ecNumber evidence="1">3.4.13.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.19" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1R9"/>
    <dbReference type="STRING" id="6689.A0A3R7M1R9"/>
    <dbReference type="OrthoDB" id="445695at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443:SF12">
        <property type="entry name" value="DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="MICROSOMAL DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU341113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="21956" checksum="9B7D8D06E5173D4B" modified="2019-04-10" version="1" fragment="single">MFTRSLGVSSTKPRAPLAPPLTPTSPSLRHNDLAWNLRKFLHNKLHSFNLSYDLTQEKPWRKSPFSHTDLPRLREGHVAAQFWSVYVPCETQYLNTVQLLMEQIDVIKRMVAASSGETTLVTSPAGIEREFKRGYVASLMGVEGGHSIASSMGVVRALHDLGVRYITLTHKCHTPWAECSETEGNAPNARGLTPYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M389</accession>
    <name>A0A3R7M389_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein FAM50 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010006</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002267">
        <property type="protein sequence ID" value="ROT71670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M389"/>
    <dbReference type="STRING" id="6689.A0A3R7M389"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="4">
        <location>
            <begin position="164"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="37443" checksum="558ADA0290072A0C" modified="2019-04-10" version="1">MINKIENKFAVHYDAVEQQLKSSTIGLVTLNEMKAKQEDVVKEREKELARKQKEQEKLMKKEIEAKQAKKKEQRDKIAKLSFCPDDEEEEEDEEDEDEAERKKEEEQRIEARKMEESKKGFRMVKNPDVDTSFLPDREREDAENRLREELRQEWVAQQEAMKNEEIEITFSYWDGSGHRRSVRMKKGNSVYQFLQRGLEILRKEFNELRTVSADHLMYIKEDLIIPHHYTFYDFIVNKARGKSGPLFHFDVRDDVRLVSDASVEKEESHAGKVVMRSWYERNKHIFPASRWEPYDPQKNYEKYTIKDKNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4P1</accession>
    <name>A0A3R7M4P1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative DNA repair and recombination protein RAD54-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008766</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002107">
        <property type="protein sequence ID" value="ROT72826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4P1"/>
    <dbReference type="STRING" id="6689.A0A3R7M4P1"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="12406" checksum="57E8A477439C6983" modified="2019-04-10" version="1">MQEEMYVKFLNSSAVRKQITDGDRRLDNSALAAITSMKKLCNHPDLIWEKVMKKEQGYAGLAEFYPANHDPRRLRPELSGKVAVLDTLLALIRSKSDDKVVHIQLHSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M559</accession>
    <name>A0A3R7M559_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative COMM domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002808">
        <property type="protein sequence ID" value="ROT67448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M559"/>
    <dbReference type="STRING" id="6689.A0A3R7M559"/>
    <dbReference type="OrthoDB" id="77522at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017920">
        <property type="entry name" value="COMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037361">
        <property type="entry name" value="COMMD10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12333">
        <property type="entry name" value="COMM DOMAIN CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12333:SF0">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07258">
        <property type="entry name" value="COMM_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21672">
        <property type="entry name" value="COMM_HN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51269">
        <property type="entry name" value="COMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COMM" evidence="1">
        <location>
            <begin position="119"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="194" mass="21727" checksum="F11AE5FE64557942" modified="2019-04-10" version="1" fragment="single">LQEGISLINATDINKVKGLLGRVCASLCAGHSQVFSEEEEEKLSASLGLPVEKTRQLIYTNIYIMQQAAHGMVRPIFLGEQLQACEMTPDRANVFVEHWTTHAKQIVETLRQQSLSEKQLADISWELHLKTASSGCARQTHPIAHLQLNLSNSKEPSSTKVGPTESVVMQFNQDQLYQLYDQIEQIQANLDALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6B3</accession>
    <name>A0A3R7M6B3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008412</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002057">
        <property type="protein sequence ID" value="ROT73184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6B3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051251">
        <property type="entry name" value="STK_FNIP-Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32134">
        <property type="entry name" value="FNIP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32134:SF169">
        <property type="entry name" value="FNIP REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="63459" checksum="36C98B34053962CD" modified="2019-04-10" version="1">MISFRSLRLTSLEAHFTRGSLHSRLTSLEAHFTRGSLEARFTRGTRAHFTRGSFTRGSLHSRLTSLEAHFTRGSRLTSLEAHFSRLHSRLLEAHFTRGSLHSRLTSLEAHFTRALHSRARGSLHSRLTHSSSLHSLTSLEAHFTRGSLHSRLTSLEAHFTRGSLHSRLASLEAHFTRGSLHSRLTSLEAHFTRLTSLEAHFTRGSLHSRLTSLDFTRGSRLHSRLTSLRLTSLDFTRGSLHSRLTSLEALHSRLTSLEAHFTRGSLHSTSLEAHFTRGSLHSSSLHSRLTHSRLTSLEAHFTRGSLHFTRGSLTSLDFTRAHFTRGSLHSLTSLELTFTRHSRLTSLEAHFTLRGSLHSTSLEASLEAHFTRAHFTRGSLHSAHFTRGSLELTSLEAHFTRGSTSLEGSLHSRLTSLEVTRGSLHSRLTSLEAHFTRGSLHSRLTSLEAHFTRGSLHSSSLHSRLTHEAHSRGSLHFTRGSLHSRLASLEAHFTRGSLRGSLHFTSRLTSLEAHFTRGSLHSRLITRGSLHSRLTSLAHSRAHFTRGSLHFTSAKRGRCSSALEVTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M705</accession>
    <name>A0A3R7M705_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_012983</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX41 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002626">
        <property type="protein sequence ID" value="ROT68864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M705"/>
    <dbReference type="SMR" id="A0A3R7M705"/>
    <dbReference type="STRING" id="6689.A0A3R7M705"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043186">
        <property type="term" value="C:P granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008432">
        <property type="term" value="F:JUN kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17951">
        <property type="entry name" value="DEADc_DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000449">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000657">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044113">
        <property type="entry name" value="DEADc_DDX41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="205"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="400"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="81"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="174"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT68864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="620" mass="69990" checksum="5591E6097126A286" modified="2019-04-10" version="1">MDSPKKLKRYRREDPKSSSDEEEDSYEPYIPVKERKKQRMKQILKISQDEDASTDSWKEREQREQEEDVQELARKNNISLLDQHTELKKIAEARKESELEKQRREEKRLLEAVAEKRALMGVSELARGVQYEDSVVTAWRPPRRILAMDEKRHERVRRKYKILVEGDEVPPPLKTFADMKFPRCIIKALQKRGIEKPSPIQMQGIPAALQGRDMIGIAFTGSGKSMVFILPIIMFCLEQEKKLPFMGNEGPYGLIIVPSRELAKQIKDNIEFISKFVEADGMPELRTSLAIGGEPVAAAMQVVRKGVHIMVSTPGRLIDMLDKKMVRLDVCRYLVMDEADRMIDMGFEEDVRTIYSYFKAQRQTLLFSATMPKKIQNFARSALVKPVTVNVGRAGAASMNVTQEVEYVKQEAKVTHILTCLNKTSPPVLIFAEKKQDVDLIQEYLLLKGVTAAAIHGGKDQEERSAAVQAFQRGDKDVLVATDVASKGLDFPGIQHVINYDMPDDIENYVHRIGRTGRSGQHGVATTFINKANDESVLLDLKHLLIEAKQKVPPFLLMLGGGEDDLMAALETNEEDERGCSYCGGLGHRITACPRLEAMQNKQAAGIGRKDYLAANAADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M961</accession>
    <name>A0A3R7M961_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Myosin light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Myosin is a hexamer of 2 heavy chains and 4 light chains.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001774">
        <property type="protein sequence ID" value="ROT75420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M961"/>
    <dbReference type="SMR" id="A0A3R7M961"/>
    <dbReference type="STRING" id="6689.A0A3R7M961"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005859">
        <property type="term" value="C:muscle myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF33">
        <property type="entry name" value="MYOSIN LIGHT CHAIN ALKALI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="3" id="KW-0518">Myosin</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="151" mass="17334" checksum="0052D1993B975C80" modified="2019-04-10" version="1">MAKELSARDAERVKFTFSIYDFEGNGKVDAYYLGDCLRALNLNPTLALIEKLGGQEKKKVKMMTLDEFMPIFAQVKKDKDSGSFEDFMEVLRLYDKAENGTMMFAELEHILLSLGERLEKSELEPVLKECCQQEDEEGLIPYEPFLKKLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MA69</accession>
    <name>A0A3R7MA69_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001562">
        <property type="protein sequence ID" value="ROT77156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MA69"/>
    <dbReference type="OrthoDB" id="6347961at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="56311" checksum="A6355EE1DB95CB1A" modified="2019-04-10" version="1">MLATKRLLPRLPAAASYGLPRCLAGPSRAPRFSHAASKSAENGVLWLHPAGGTIERLDVAAKYAQLNLLGCLTINSCLPLEPAHFEEALKHLHRKISPLRACFRWREGTLWVCEALDPQLDFLVLKDSDVTTTINKLLIQPFENSAEAPLWRARLLPAAPGVPCPIPEMKEKFPHQYDLMLHIHHGLSDGITGFVIFSTFLKLLEAVVLGSPISKEQLGKLVSGEQSMDIEGEVLKNLESRPDEFQRMIDETANTKFTPLLEQAFGTPEEGISPTEYVMTDIEPRLLQNFQERCRSHGVTVNSGMTSVINTALVELVADAGLERDAYSITSRHPVNLRRYWNGDPVTAMGNHMGAISHTMQIPRHNRNTFWEHAKQFDTEFRRKLNDGDIFREKIVRSKTLPKDYSHDSFYGSPPTSIYDYMFSNILTPGFSDYGIGKTVQLTAAKNISNISNCEYSSMHLLSWFRDRVTYNIMYASGRVSRSTVQAFMSRIVTVLDRFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MB61</accession>
    <name>A0A3R7MB61_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001571">
        <property type="protein sequence ID" value="ROT77057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MB61"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="43598" checksum="FB48D60E97D095F4" modified="2019-04-10" version="1">MNIDEKSSLLSLLLLPSLLSLSTLLFLPPSHLLFHSLPFSSSSPPPFPNSLPSSSTIPRSLSPSFHNSFSLSPSLSPLVTFSLYIRLSVYHSSSPSLPSSVLFPFFLLTSHFIFWSHIIWSLLPPHFFLFFSPLPFHSSFLSLFPTLPTSLFLPPFLPVSFPPILGLIPCFPLPLLILIFFLFSLSPHPSLPPSLPLFLPLSSPNLFPPLFPPHSPSLSPPHSLPLLSSPLPTQPPLLPSLHTPTSLLLSSPLSPTHPLPPLLPLSPTHSSPSLSLPPSSLPPSSLPLSLSSPPQLPPPSSLPFSHPPSVPPSPLAFPTPISLPPSLPLSPPSTCLPLLPLSPTPPSLPPPSLPPSLSSPPPLPTPTSSLPCLPLSHPNLPPSLSSPSPPHPTSLPTSPPPLISFRHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBS7</accession>
    <name>A0A3R7MBS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative CCR4-NOT transcription complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009188</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002158">
        <property type="protein sequence ID" value="ROT72423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBS7"/>
    <dbReference type="STRING" id="6689.A0A3R7MBS7"/>
    <dbReference type="OrthoDB" id="551431at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000036">
        <property type="term" value="P:regulation of stem cell population maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20271">
        <property type="entry name" value="Complex1_LYR_FMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.1020:FF:000005">
        <property type="entry name" value="Regena, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="292"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="112"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="546" mass="60590" checksum="08C796A2B349DBB7" modified="2019-04-10" version="1">MFNRKERIMGSLGGTVARSIESRGIASGPSVGSLVSSGSGSSGGSSLAALSSAVAATQNTNSLFMANSIQTATQQRAVTDMLRHMQGLGNRSITGIVGRPYGSGGNSMMGLHSNFGGDSAPPPLDLSEFPSLSSRSTDNSQPNPMAGRQPYVGMVKQPTPETSEFTMSSEDFPALPGTQSTPTGKIFSPFSDDGGFSNNDKKSTSTASSESSSDFSLRVAEKRESMRRGIQTRADGKVTNIPGDMVTDQFGMVGLLTFIRAAETDHQLVSLALGSDLTTLGLNLNSPENLYPNFGGPWAETPCRPQDIDYHVPQEYLTNQQIRGKLAPVKFDRYGEDLLFYMFYSNAGDVLQILAGSELYNRDWRYHKDERVWITRAPGMAPVEKGPNFERGTYFYFDAQNWRKVPKEFHLEYDKLEERPHIPGDCLRRNNTAFRRSSLEMASTAPKLQVLRSLIKELRNSLQGHERVRHSPAFTYIMDNYRRNAVTDQQYCREQEEMVHLAHTCATYLKSNRKYQELHAEYHGRGERTVKETADLVGFKLPHDPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD48</accession>
    <name>A0A3R7MD48_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">COMM domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the COMM domain-containing protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002052">
        <property type="protein sequence ID" value="ROT73211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD48"/>
    <dbReference type="STRING" id="6689.A0A3R7MD48"/>
    <dbReference type="OrthoDB" id="1917519at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04751">
        <property type="entry name" value="Commd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017920">
        <property type="entry name" value="COMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037355">
        <property type="entry name" value="COMMD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31159">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31159:SF1">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07258">
        <property type="entry name" value="COMM_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21672">
        <property type="entry name" value="COMM_HN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51269">
        <property type="entry name" value="COMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COMM" evidence="3">
        <location>
            <begin position="121"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00093469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="192" mass="20894" checksum="9E22044EE9649DAB" modified="2019-04-10" version="1">MDLSLEISSALRLLGNSTNFGQAEFKKVLQKATDDLINSGKVPVTSTGSGACDGTIARSHAALATLFIEAVKSNQDGTIVTSTLEDFNWPAERISETVKELDSCRERIRSKLASVGTYPPHIVDVDWKLDYHVRSSAGEEGGGAFYLITLHTEESDGRRGKVTFSCSLAQLSHLVTQLRQASRCIQKYANNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD82</accession>
    <name>A0A3R7MD82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001237">
        <property type="protein sequence ID" value="ROT79479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD82"/>
    <dbReference type="OrthoDB" id="6360987at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018581910" evidence="2">
        <location>
            <begin position="23"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="625" mass="69049" checksum="525830E0CD640697" modified="2019-04-10" version="1">MTRPRVPSAWSVGPWAFTVMSACLVTALLEDDTSNKDHIVPSYTSVDDSEDLMAFHKRAWQVAANSRYYRPTFDGQKQGKEAPDTPFLEEATSARQADDVLPDSPPVDGMTEAQRQMVQLLQERDWRVVVRDPSFRELLKKEMVRSGVLHDHESIIQAATEAAERVEESTDGKDDDEELLRQIVDEAEVRGLDSGKVAGLERELRGALRREPRQNSIYDVLDGVRNYNSPKASRKGTRHRHEGYNTGSPFAVVPLNDMMGIFQALNGEYGAASSSYASPPSSGYGAPPKSSGYEKPPKYVHLPPIKGPTYYPPIEVCPSGHSGVFAFFAFITLTLTLMIDFTLSVMVDINATGIGGIDVLRDTRKTRDASDSFPETPATESDSDRPRIIFDRWKRLLPHGSMFVFPKAKGEVATTASEIERFGFLKQYPTYGSENPQAEDAASQLLEVGQGVFLSRDASKREGNRDSRPPFPPMTRRQRRAQQRRARRLSATRPEDVPNLHYQSVILPGNKINLREWCLGGRECHEAAVRAMFSVARGYMLALAETQRHCALWFICDASARAIAEGAVGAMAATLASGVTSLYPTVVSGAGLREVISARNVGLRTADCSRFLVRECRLANGGEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEN4</accession>
    <name>A0A3R7MEN4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="3 7">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_007122</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3 7"/>
    <dbReference type="EMBL" id="QCYY01001906">
        <property type="protein sequence ID" value="ROT74379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEN4"/>
    <dbReference type="STRING" id="6689.A0A3R7MEN4"/>
    <dbReference type="OrthoDB" id="36455at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00948">
        <property type="entry name" value="FBP_aldolase_I_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000021">
        <property type="entry name" value="Fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029768">
        <property type="entry name" value="Aldolase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00158">
        <property type="entry name" value="ALDOLASE_CLASS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT74379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="42699" checksum="DE28A89E73A3D8FC" modified="2019-04-10" version="1">MVFIPGTRPPTPAENGRRKEHPITPHTFRSTMTTYFSYPAPELQAELRRIANAIVAPGKGILAADESTGTMGKRLANIGLENTEENRRKYRQLLFTSEKELGNYISGVILFHETLYQKTDDGRPFVDLIKQLGIIPGIKVDKGVVPLMGSEGESTTQGLDDLSQRCAQYKKDGCDFAKWRCVLKIGKNTPSYQGMLENANVLARYASICQMNGLVPIVEPEVLMDGSHDLERAQKVTEAVLSFTYKALVDHHVFLEGTLLKPNMVLAGQECPTKYTPQQAATATVLALSRTVPAAVPGICFLSGGQSEEEATVHLDAINKCTAGRKPWALTFSYGRALQASALKAWSGKDVKAGQAELLKRAKANGAAAVGKYAAGTVAGAAGDEGLFVKNHQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFR9</accession>
    <name>A0A3R7MFR9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001114">
        <property type="protein sequence ID" value="ROT80493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFR9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="44443" checksum="1E3A56E355772A3E" modified="2019-04-10" version="1">MGVDQKPLISLARRTVRPGVKSTADYEARQGKELPLGQRRAFAEGSRARRRKELPLGSRERFAEGHHELGGEKELPLGLEGRFAEGHHEARGERNCRGVQKGGSRGTYDEAAGVQKGVPEGHTEATVETRTCRWGPRRAVSDDGITRGFDYGIKNCRVGARRRKNCAVGSEGRFAEGHHRGRRRKELAWGSGRAVRRGIITRLGGERNCRWVQRAVRRGDITRLGGERNCRWGQKGGFAEGHHEARRRKELPLRVERAVRRGTSTRLGRERNCRWGSRGRFAEGHHELGGERNCRWGRGGRFAEGHHEARRRKELPLGFRRAVRRGTSRGSEEKGTAAGVEEGGSLRDITRLGGERNCRWGSEGRFVQMDYLFTRLEEKELEFEFSPGFSRGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGT4</accession>
    <name>A0A3R7MGT4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000859">
        <property type="protein sequence ID" value="ROT82212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGT4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="127" mass="13827" checksum="2626ED6A7AB43348" modified="2019-04-10" version="1">MIIPSIPSPIPTWTGHRRASRKWRSLPWATARHKPVFWAALASGSEPRPPGDSVAGASLGRGSTPGRATLSSLPRSPDSSLVALLEAGREQEGERGWRLATGPWWRARTARTSSTGRPWLPITRLVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJN9</accession>
    <name>A0A3R7MJN9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_002737</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001367">
        <property type="protein sequence ID" value="ROT78532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJN9"/>
    <dbReference type="STRING" id="6689.A0A3R7MJN9"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048675">
        <property type="term" value="P:axon extension"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010508">
        <property type="term" value="P:positive regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000493">
        <property type="entry name" value="serine/threonine-protein kinase unc-51 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048941">
        <property type="entry name" value="ATG1-like_MIT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022708">
        <property type="entry name" value="Atg1-like_tMIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12063">
        <property type="entry name" value="ATG1-like_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21127">
        <property type="entry name" value="ATG1-like_MIT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="338"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="718"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT78532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="904" mass="97000" checksum="6F9E9F2234C62722" modified="2019-04-10" version="1">MSDKNSIPRLVREVSVPLRATTTAGADRGAVGGFGTRGWYCNGGDLADYLHAKGTLSEDTIRYFLRQLAESMRALFGKGIVHRDLKPQNILLAHAGKPNPAPHQITLKIADFGFARFLQDGVMAATLCGSPMYMAPEVIMSLQYDAKADLWSLGTIVFQCLTGKAPFQAQTPQALKQFYEKNANLAPRIPSGTSPELVDLLMGLLKRNAKDRMEFETFFNHPFIRMVDSSAQKPSVATGSPSVPVRSPSPAPATTPKPVSRGGAYAHHTQPSPSPPVGNLPPSPEELRMSVDQRSAGDLPPASPASATTTLPRPTPVPRANNAPAPEEAEDFVMVPAQLPSEPEPSRGAQGWGGRALTKAGGGIMYQKNQPQYGPLTPQVPTSPRPSHLPVQGGSSGSTHSSSSSESCRSGEPVPVPSQRATFHQMTSSGSSDQISATLQPESPRHHGIPTNRPSPPPRSQPINMRRVSDHRAPDVASLSPPAVQFTIGTPPMGGRRRSTSGSSYSTTPPTSAAATGNNQVVPGGRLTPTNSPLRQSGRRTPPHLPPQMFSAPPVLPPILGSPTKLGLGQDNPAGDICGNTTLTAPHRAITLPEMTSVSRDPFTGGSQDMSVDGSGLQRSRTESHLLEWQAQAPSPPHPGRQLVQYGQSAPAFLLQGTAQAEGDDTVAFYAPPLHQETLMEREHNETLAKLNFVLALVDCILELARSRAAPITALRQNAAMRDSVSGSPKDTEGSALASPPPEWQRRAEQLVLYVRALQLLSSALTLAKHEKSTSRLQPSNAVKNVVGVLSERFRQALGVCKELNSAGAITSVDPRTSTVTADKLIYNYAIEMCQSAALDELFGKPEECFRRYQTAQILLHALAQQVAHESDRSLLTRYKQAVERRLFLLHEQGVVHAYTTNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJR0</accession>
    <name>A0A3R7MJR0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003432">
        <property type="protein sequence ID" value="ROT63495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="628"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="888"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1306"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1403"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1454"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1476"/>
            <end position="1495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1506" mass="164043" checksum="A6DCD05002A67C65" modified="2019-04-10" version="1">MKPGSLVNRWRAPRWSGAEDGGESDTSEASARSLGRRPQYSRAPSRELHNIPDEELGLLGGRAYSGGGMSLPRPYPGTSSGLTAQGRMMHDSADRIASMYGTLRGPHRRPHSTVGGHPGEALGRDGGHCERQSTNGSAAHTGVHSSQRASQLSPSGSTVQSPEETEALKQSVQEQLQQLVRELEAGEDQLPLAPQPQPPPEQQQQPQQVYLPPSVKALVSPPGTPMFTPPTTPLQPHNTLPGSLETQTLSEETTPYSTPTPSLSHFPISPTSPVQSIQSPLTTPSPLPQVHFRSHSDDAAAHGRATGTTVKDSFTNSTVPKQGHKVISQASGPTSRTEGGGQDRTSRGLLTRIGGNEQVGYNAILDISRERATSPASSDSTEFGHVKRVSSNNEEWLKPTGAVVRNVDNTALEAYRRSRGKGDIMEYQRGKSEDLRHTLDSLERLENQKSRITPSRPTFCRDPPLDERTYSNIGDFNRTNTGTPAMTAANLQLHNQLVAANSANSNINNTDPTNTNSTGSANTLGRANSNICASNDQNNNNGLPTSRSASGIPVKSNSRGSLSTRSSFSGNSISGTKPGELLQPKTYRRSKSKELTPAIEAAGEKLSQLNSGTLKKISPFEAYRRTKSRELPLETVNRDTRIKSPPPAGPERAKSPFERARSSIEKKFERAKSPLAERAANRKSDFPAGKAPVSPIMNRSSNIVKDEDRPAETTKIPEVENVQASDRTKDMEREKAKEIEKETEKDKQKDNKVKKTSSCDPEKPKSMYKLLASRFNRSGSNVPDSSVRSTTDKRSEEEDVSEREDKFHLKRPSRFLKHKTEKSSSKSSVCDEDGSERLERKPSKKLTDALNKFLGRKESKGEEARAATNTLQHPSVLVTGTEEEHPKKPPRVKPKKFSKSHENLCLSSVAEGGEIVTDAQQTDKMQAAVPQVAATTSQPGFTLESVTKSICDHLSQLESDITSRIGNMGVHEQGTVVRPTGTPCRLPTASSVPSLTTYGLSPALASRRSARPTNLDLAAAGIDNHKAPQASQAHTVTTASKDSNHIPVSESEGVKYAQIKKLGSGTGEVAPSEDGSQTPTESGESTTSGPDDQRGVSENDDESVMDRITRKSYYSRFQEIKKPKLRRANTKEDMDQQLAAAKARLMKEDQERAMRDTLSPHKYTSPLGSPRANVTSPPSWENPRRHSRKSLPPEDLSQAYSGGRRGASLQPDDLPGIRRLTSVQPPDVAMGVKRRLPSMPPDERIRSFRAPSTPRESLSGRRVKSIPPEDKMYGQRAPSTQPEDIRRPSPVKSPESPEPTESWSSAKDETRTQAREELSRRLTHLTRISGTSGIAAAKRNVGLAGGNASDGAGIRPYRRTNTTGLLGEPTSTQPGTSTSTGKTLTERPAYRRTNTMDLPPADARARPGSEYRRMLQDPARRYSAARCPASDGTPARWPPPVLQRTLVEDEALNTTPTRTTSRLTSPTPQSSASSSYRNYSTLDSPRYSNASSSITPLSRRTSFYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK55</accession>
    <name>A0A3R7MK55_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thrombospondin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_002434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001321">
        <property type="protein sequence ID" value="ROT78855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK55"/>
    <dbReference type="STRING" id="6689.A0A3R7MK55"/>
    <dbReference type="OrthoDB" id="14563at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1080.10:FF:000001">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017897">
        <property type="entry name" value="Thrombospondin_3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51234">
        <property type="entry name" value="TSP3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="162"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="4">
        <location>
            <begin position="279"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="4">
        <location>
            <begin position="338"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="4">
        <location>
            <begin position="376"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="4">
        <location>
            <begin position="412"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="354"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT78855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="47924" checksum="FA054827A0541A53" modified="2019-04-10" version="1">MGLTLVMALDGSECPGEGRFSDASTCGGFIECIADKTGGYSVKRDHCNGYVYNATSMTCSQTLCDSRRERSVTNDYHPLSQVCESQPDRFLCANCKTLVHCVMGQAFVRQCIKDFYCTEKPGFGGAVCYPDEPAAWKCVEATDEYLGYPFAHCDIPDDLCPETDPCLQNPCYSGVACTFTSVAPFYTCGACPAGFTGDGETCDALQCPVGFAGIGGDCAPDSDLDGFPDTELGCSSKYCRKDNCDNCPLTPNSKQEDADSDGRGDVCDNCPAMSNPSQRDIDGDQIGDDCDDDIDNDGSLNAADNCPLMANSNQADADGDGLGDVCDNCPLNPNPGQEDVDEDLLGDACDDNVDLDGDGVEDSADNCPSVANSNQQDVDGDGDGDLCDLDSDNDGVNDPSDNCFLLPNPGQEDANGDGRGDACSTDFDGDRITDANDNCIKNPNVYATDFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MR12</accession>
    <name>A0A3R7MR12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Ionotropic glutamate receptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_014170</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002765">
        <property type="protein sequence ID" value="ROT67736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MR12"/>
    <dbReference type="STRING" id="6689.A0A3R7MR12"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000080">
        <property type="entry name" value="Glutamate receptor ionotropic, kainate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001508">
        <property type="entry name" value="Iono_Glu_rcpt_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00177">
        <property type="entry name" value="NMDARECEPTOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="16">
        <location>
            <begin position="32"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="site" description="Crucial to convey clamshell closure to channel opening" evidence="14">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT67736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="176" mass="20623" checksum="3A912D3DD98D28EA" modified="2019-04-10" version="1">MLRKKAYDTHPHEEKPKSSHRSLFKFLTVLEPEVWVCILFAYGFTSILLYIFDRFSPYSYQNNKDKYKDDDEKREFTLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPIESLDDLSNQYKVQYAPMNGTSTMTYFERMAYIEKKFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSJ7</accession>
    <name>A0A3R7MSJ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000490">
        <property type="protein sequence ID" value="ROT84835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSJ7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="521" mass="56650" checksum="10926BB36383316F" modified="2019-04-10" version="1">MSESTCPHTPASPTPRRQPNPEPHKVIPLRKPTKSIPLPRPTNHRTHSQTHPKQTIPLPHPTNPSQLPSPPQTHPTPSPHKPIPLPHPQTHPPPHPTNHPTPSPQTHPTPSPLPSHSLTHKTSSHSLTPQTHPLPSPTNSSHSLPHKNFIPLPHPTKPIPLPHPQTHPTPSPHKPIPLPHPTNSSHSLTPQTHPTPSPHKPTLPHATNPFHSLAHTNPSHSPTHKNAISTPHPTNSSHPTPLHPPNPQTLPLPHPTNHPTPSPHKPFHSLAPPHKQTSHSCPTKPHPSPHKRIPLLAHKLIPLPRPQNSIPLPHPTNSSHPSPHTNPFLTPSPHKLTSHSLTPQTHSTPSPHKTHPHSLTHKPIPLPHPQTHPLPTPNSSPPLHPTNPSHSLTPQTHSLPSSHSLTATNPFPLPRPTNSSLPHPTNPSHLSSHSPPKNIHSLTHKHPTPSPHKLIPLSPLPQKLIPLPRPTNPSHSLTPQPHPTPSPTKPVQLPHPTTSSPPSPHKPVQLHPTNSSHPLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MT65</accession>
    <name>A0A3R7MT65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">H+ ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_017770</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000328">
        <property type="protein sequence ID" value="ROT85297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MT65"/>
    <dbReference type="STRING" id="6689.A0A3R7MT65"/>
    <dbReference type="OrthoDB" id="7357196at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018536877" evidence="13">
        <location>
            <begin position="31"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="15">
        <location>
            <begin position="150"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="14">
        <location>
            <begin position="262"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT85297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="970" mass="110947" checksum="CAEE9649B88DB4B6" modified="2019-04-10" version="1">MLPKENNKHLGFSTQVSVLLLCALTCGVAGQGVKVFSLQENLWDAPRTDVFVRYNLSLKTPVAASNGWEVTICYRVLAVALSPFEMHFSLAVSDYNSDSFLTCKDFPFPVYRQAEQNWFQYDDKIEYGFADFVTALRLRQWVHYCHLFYSGQYKAFVDGAEVVSGPLANAGAPVPLNGTLVLGQEQDMMGGGFDRQQVLRGRITQVNMWNRTLSADEIRSMASCAAYELGDVFSTDREEVELFGVQVETESLSSFCRPYSEYVILPESRDMKGSLQACHRIGNKVFAPETRQQNRQLYLESLQFNATCPSNFHMWVGLSDELEEDRWRRFSDNKTVRETSFVPGFPNGGTSENCIYMSRISGLWEDIACNREWFACVACTEDFGRPLVLRGLCEKKKAETMFETLGYRERKPFFHGYYGKMIFKTPTGDWELHDTTTNVTLAALALDTSDDYPLGRHIWILRDTVCDHTVSTELELSLSACFDNEYTCANGECIAKDLRCDTRDDCSDLSDERDCTLMEIPSGYRDQRPPEGKLDGGALEVVATIKILRFVEISDVRRMVRMEVEVEIKWKDTRLRYLNLKDTLEWNKLTDIEKSAIWRPQFEFPNVYDGKVDRFKEQLYVEKIGHPLKTDFNDAKMDVVYSGEAAIFLQQQHYSGSFACSFDVFHYPFDVQVCHVLVQLSSVREEVVRFSQKAKVVYLEDVNLPSYIVTRYEAFVTTRGTEKTKYSVVEVEFELTRRWTVIVLSVYFPTSLLLIVGYATLFVSVAQLEVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRQGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGKDLQAMKAVVGEEALTSDDLLYLEFLAKFEKTFISQGPYMKRTIFESLDIGWQLLRIFPKEMLKRIPAATLAEFYPRDRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MUK2</accession>
    <name>A0A3R7MUK2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pentraxin (PTX) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_011652</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002470">
        <property type="protein sequence ID" value="ROT70082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MUK2"/>
    <dbReference type="OrthoDB" id="6353068at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018602912" description="Pentraxin (PTX) domain-containing protein" evidence="8">
        <location>
            <begin position="25"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="588"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="674"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="9">
        <location>
            <begin position="29"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="376"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT70082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="699" mass="80080" checksum="4858523FF2C5A3AC" modified="2019-04-10" version="1">MTPTNGRLLVIMFVLGLATYLTKAQDPQRSPGSVRLVSFQASEAASTNSSLRLLPDFPEMAAVTLNLWVRFRHFSPALDIIVSYFGFNDDLLHFWHDFVDSELVFRVYGYKVTTPVEIPLYVWNHITITFELVSSKYHVLVNDKEITSNLTIDYENRIGKNLPGGGVLILGQDQDSPGGGFSIPQAFSGDLADFCLLSQYFPLNNLKDFRCYEHTSIEKSLRLDAEEDWSLDGDVKAFLINTSTLDYKFREPYVMLPEQKYFPVNSIQIRGLCSESQLDRQLHIDGTMNLRPVFHGTFYTKVWWDNTSWVMASRLLPNLKATMINNDPEDYPVGLHQWLLSGDNCPAGEVDLLLTVCGEESFPCNDGTCVHMSHRCDLRAHCDDGSDEMKCDKVFVGTDYEKTLPPPPPETEDVLNVTLSVIITAVRTLDLLDQTVTLDVQLISEWEDPRLQYADLQPEQFKNQVQDIDRIWQPRLITTDDTGSLVDLMNRDMFLVVIQESEPLPSDDTRYIKAIVFPGSGNPLLLRQELSITFQCQFDLLWFPFDNQRCSINFRLNDVESKLVRQVTLKGKDETSGQKLTIVFTNLFLYYLANSYLPSFLLVVISYSTFYFRLEDFNERIMVSITAMLVLVALFQQTSSTILKTTYLKLIDVWYMPQHRDQDMSRKYNMMARVGLPIVFFLFLAVYGIIAAVQYFTGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MUQ7</accession>
    <name>A0A3R7MUQ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002454">
        <property type="protein sequence ID" value="ROT70192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MUQ7"/>
    <dbReference type="OrthoDB" id="6348747at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="217" mass="23633" checksum="F6A7F1AF59F2CC7B" modified="2019-04-10" version="1">MRLYSFHRLCTSVKTLLILLPEDVHWSEYSSLSCTSFWYRWLQTRGLRSSKLCEAADDANTCRDCAKGVSDFKQEMRTCTSDLSVSCSNITTTDLDSLTTCLTDALPDTLPFVAMKGFVVASVIALLLVAIAETHKGHPHQGRPFLCIKKLCDSAANSTGCGPCLREAHTSGSVEKEVLRPCFEAASGCFDISTEGLDTLRTCLSDASEVVGNCIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MZW0</accession>
    <name>A0A3R7MZW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002017">
        <property type="protein sequence ID" value="ROT73587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MZW0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="46282" checksum="8102A526662F2B16" modified="2019-04-10" version="1">MHYKYFSVLYILYPLIYFSIYSPTFPALPLVSFLSLPSPSSHSPPPTSLLPSPPPDSKPNPSLSSTRITIIFPYSLESHSPPPPLIFFTPLPPFTLPPLPSLSPSPSVPLSPSPFLLPCPVSHVPRPFPTLLPSFLPPPPTLPPPLAPFLSPSIPSFPSCSSLLYLTPSSLPLRLPSPPSPPSPCSLSPSLSLFSFSFPLPSHYSFSPSPLPFPSFSLLYYLLPLAPPSSTYPLSHHSPSPPSPNLFPLRPPHHPDAPSLPLPSPSPFFSLFLPLTLIHSIIPPPPPISSHSVSLPSPRISCLIPVPPFAPPSSSRITFSPLPSPHPRISFAYPSPPFHPLPTTESPLLSRLIPLPHPSSSSPPISSPFPSFFILPPFHSPSHFHPLPLPLPPPSHPLPTFHPLPPTPRSCPERSKANVITPCDAQVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N8P7</accession>
    <name>A0A3R7N8P7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative 5-hydroxytryptamine receptor-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_000975</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001135">
        <property type="protein sequence ID" value="ROT80279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N8P7"/>
    <dbReference type="OrthoDB" id="10034726at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071880">
        <property type="term" value="P:adenylate cyclase-activating adrenergic receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF199">
        <property type="entry name" value="IP13425P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="107"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="46"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT80279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="36426" checksum="D38FE858BCB080A9" modified="2019-04-10" version="1">MNSWCVFYEGGLWGRASLLVERGRGTVIEAVTEVSKEWTLGPELCDMFWAVTNVDYIHHRSPRRVGGMIAAIWIVSFLVSAAPMMGWKDPEWHDRLAEKMCIISQDVGYQIFATITSFYLPLLVILILYWRVYQTARKRIRRKFGTNAQSALCRGPITISETTTFARMATQPSPEKTSNGSTLNGHPMDASREDSTSGSQAAITHVLPRQLRRREGELRKERKAAKTLAIITGAFVMCWLPFFILAVLMPLCPPSFCNFNPYLIATFLWLGYFNSTLNPIIYTVFSPEFRNAFKRILCGRKRTLQRQTTRFAAVRFTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NA25</accession>
    <name>A0A3R7NA25_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative carbonic anhydrase-related protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_025440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000981">
        <property type="protein sequence ID" value="ROT81402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NA25"/>
    <dbReference type="STRING" id="6689.A0A3R7NA25"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF208">
        <property type="entry name" value="CARBONIC ANHYDRASE XA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="3">
        <location>
            <begin position="38"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="297" mass="33406" checksum="7E0ACBEC3EF4547E" modified="2019-04-10" version="1">MSLSRRFQQGERGAIDSVMGRQKRRGSSSSPPGINWSQWWTYDGISGPRFWGVINPAWGMCREGRRQSPINVDPKTLLFDPNLTPFTLDKVTVAGELINTGHSVEWRAARDSVMVNITGGPLSYVYTVTHARLHFGERDQQGSEHLLDNRAFPAELQLYGYNSQLYRNFSQASGQVYGVVGIALLVQLGERMTPEFRVLLEGVDSITYGGSSVAAASLVVSGLLPSTEHYLTYEGSLTEPACHETVTWIIPNKPLYINVAMTGLFSEFQSINELLLFKMGWAFFDEWAEWEMRRVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NT89</accession>
    <name>A0A3R7NT89_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Actin T2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_015885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NT89"/>
    <dbReference type="STRING" id="6689.A0A3R7NT89"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000148">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT66117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="138" mass="15633" checksum="0456ACFAB95E7B9C" modified="2019-04-10" version="1">MEKIWYHTFYNELRVAPEESPTLLTEAPLNPKANREKMTQIMFESFSLPATYITIQAVLSLYASGRTTGQVCDSGDGVTHVVPVYEGFALPHAILRLDLAGRDLTNYLMKVMTERGYSFTTTAEREIDTFRAHRSHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NVQ8</accession>
    <name>A0A3R7NVQ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002727">
        <property type="protein sequence ID" value="ROT68013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NVQ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="147" mass="16024" checksum="61BA579C856667D8" modified="2019-04-10" version="1" fragment="single">SKASALGVDNIGGVFVVLLCGLAFAVLIAILEFCWNAKRNAQIDRDCSMHLGERQFKQSLCSEMAEELCFAMRCRGSRQRPALKRQCSRCIPGATYVPSALEVPHLNGNGETGQTGTNELRPRKSSLKTSLPSLAPPYDLKVTPDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5M6</accession>
    <name>A0A3R7P5M6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase 16 kDa proteolipid subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">V-type proton ATPase 21 kDa proteolipid subunit c''</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Vacuolar proton pump 16 kDa proteolipid subunit c</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_020307</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003962">
        <property type="protein sequence ID" value="ROT61879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5M6"/>
    <dbReference type="STRING" id="6689.A0A3R7P5M6"/>
    <dbReference type="OrthoDB" id="10264021at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="52"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="13">
        <location>
            <begin position="141"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT61879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="210" mass="21916" checksum="921EA5A36D5DF241" modified="2019-04-10" version="1">MGYVKGYLQYGLYLYLLLLLAIGIGYTITGQGERIDFGWFLSSVSAYFWGAIGIGLTVSLSVVGAAMGIHTTGVSIVGGGVRAPRIKTKNLISVIFCEAVAIYGLIIAIILAGILEEYSETKANANEDIFEQNLLSGYLMFAAGLTVGLTNLFCGLAVGIVGSAAALADAADASLFVRILIVEIFGSAIGLFGLIVGILQTSKAKMGDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9S9</accession>
    <name>A0A3R7P9S9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative serine protease inhibitor dipetalogastin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001225">
        <property type="protein sequence ID" value="ROT79559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9S9"/>
    <dbReference type="OrthoDB" id="6614329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.30:FF:000042">
        <property type="entry name" value="Serine protease inhibitor dipetalogastin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF79">
        <property type="entry name" value="GH09510P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="15"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="68"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="131"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="184"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="233"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="287"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="339"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="2">
        <location>
            <begin position="441"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="56508" checksum="AD31569C846D0022" modified="2019-04-10" version="1">MLNFISVAIAGAVQGRGTRGCNQICPKEVNPVCGSDGIIYSSSCDLKRQTCGKQERVVAVSDEQCLRANGGKCDHRCTSLLDPVCGSDGRTYLNRCIFRVEQCRYYEYLQLFEKSVFQVGCHLCHYGGLAPTDTNPCPSDCSDKPLDGPVCGSDGNVYNSTCDLEYRTCGQKVVKTSYKHCQTTKHCQDVCFFSFKPVCASNGRMYNSKCQMKMLNCGKHIFQTPMVHCRPQERVPGGCPITCEGETLSPVCGSDGNIYDHKCDMRRLTCGSGSAGSVYEVDIEKCRKRFEKCERIVCPSTLDPVCGTDSNTYTNYCLLHKAHCKKGVELAHYGVCPDMTTTEECPKLCPQKAEEYPVCGSDGNVYSSVCEMKRRTCNQKVVPVALHHCQATKHCYDQCQEEDGGAVCGSDNKMYRNVCEMKAKNCGRHVFEVPIKNCLAGFNFIKCLKFCPPMFDPVCGTDGKTYSNECFLQMENCRTRSLGRSLVTRIYHGKCGQPVPEAKLYMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAA6</accession>
    <name>A0A3R7PAA6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003143">
        <property type="protein sequence ID" value="ROT65108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="893"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="946"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="964"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1247"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1355" mass="148456" checksum="15A4701291946AE3" modified="2019-04-10" version="1">MESVRAFYEHPPSHATMPARDYGSVTPGKAKKSWGDLLKFRSRAKERPLEPVAPAAHTAPASHSYLAEYRQKYGAYSGTVGRASYQSMTVVKSVTPPPLPAANVPRRYPNNGYLKHGGSGTVSAATGATMSSTVRYTDWFGSVVGRRPPVRPPLPAFSAPAGPAVHPPDKAVGVGAWDHYVTLDPVYEAPRVVPVQLYTNVCMCPDQALNTKGRKKKKCKRCGRKVATVRNATSSVATKVMEERVYEQYEVRTRHYSRSPARTLSDEDESPPPTPETVRSVKSIRSVKSMKSSDSSSTITREALEPSRTAPPPPVSSRSLPPPPEPPVHSAAMHSAKENHPEDPEGTRNSILIENPSAYQLLSSHRAHVGSDTDELSDNAVDSLTDPWEGDFSPSAQERAHGKQVNVITIGDNPFPSPSFSNDKHTSHKIRINTDEAKPCLNGDILHVDDKKLHTSQLPVTNLQQNPHSNESNLSVYSSNKKGTSKISPSSTKNGPSSRNSSNKSRHKDTSSANKKIQNNTRKSSADKMASSSVSRKKLIDHKASAANGINGGSHGEVKNLHDSRELQLGGNCVRIAGQRMLVLTPGAPPPDTRSGFSSGEDEVTADDDTSDYPQSSPTTTRGSDSDTLPEEEEEELLPLDSSGLHYAQQHSSQSDKSLSSSLDSSDYRSDTSTSQSDRWMSTRDTIYEEEEEDLEDPPKVQNHIDDDAESTLLEDESEKDEPSVSSSSTTSSPVRHESFHPTLSELLKVKSILKKPSSVDTSSETDSDFYLPTFTEFKQNQRKKKQVQFRSSHDVTVIEDAGESKGRKVSSVRSPKKDRGKAKERQKNTYNLLADLQDVYSRANNPVIYKTHSKNEFSDIRLNDIPLANGECDSEYRTPDSFGEVLTSREELLEDSSQENDQRRDDKNSDSAAVGEAEEWKAEQGFREQKVDAQGGAGLPRSLKDSQTSGVSTAESTPRLRLSSYTKPPTQVITGSTSPASTPTRQAPPPPRNRTLKISRGSEGLREVLSPMGYVPVFGGTEEARTATIRGRGAAHARPTILEAFAPTPPSSALPPSSSPPVAPRRRNRNRSLSPDVPGDSTRSGQSILGGRGRRSSFLNNLLGDENPYEQITDHIYEELLLRNQSPNHSSLACHGSASNSSSPHKSPSPGKSMFEGASKYEILEYLQDARRRVAISADDDEEVRLQGDVGPSLPAEVDLEDEEEDQLGVEPPEDNFTVLTSRNRGHRSSNMSSNSDSSENSGLLRSDKKEKQSDNTEMNFRVETLMVMDWKSHLISLLTSSALKFPRRANLLSLDRLISLSHRPIRHQLFSLFLSSLAFSQRSVTSLSLRCSSLSFGDWLDAEGRLRIQGTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBK1</accession>
    <name>A0A3R7PBK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Protein TANC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_021769</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Postsynapse</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TANC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004632">
        <property type="protein sequence ID" value="ROT60687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PBK1"/>
    <dbReference type="OrthoDB" id="5958958at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098794">
        <property type="term" value="C:postsynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058018">
        <property type="entry name" value="AAA_lid_TANC1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058056">
        <property type="entry name" value="WH_TANC1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF55">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25520">
        <property type="entry name" value="AAA_lid_TANC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25521">
        <property type="entry name" value="WHD_TANC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0770">Synapse</keyword>
    <keyword evidence="4 12" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="66"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1040"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1073"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1176"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1209"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1242"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1275"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="10">
        <location>
            <begin position="1308"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="1468"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="114"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="227"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="365"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1440"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="365"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT60687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1561" mass="169083" checksum="82839664D953CA26" modified="2019-04-10" version="1">MYSPYLLFYVHSLFHTTSAAGSVILRLRGASWRDGPLPPTQPWGKEWNDLNPAPHAYARLQDGGICPICRMPFDKGKKRKLIDQCGHERCYSCLFKSETCPICALQGDAGSVHSVRSKGASSSLRGHRREILWGSPPKKLQHAQSRSSISPAGGPGRSKLLTNGTFSSYFKGGDPGLPPERPSPSRSVSPRRNVLVSQSHTLSPLYASSSPVSVSYGTLAPPQGHIYSPVGAPGKETPYGTPPTHSRLTPSPAPPKSVGGTPASARRRGIISPRGPPLSPWSRRAIRPNTVNVDSSQHLTALLSSTDKKSTKNISLVRRIKSLWSIDDECDGDTEAPSGGGGDGAEAKDGSDLYMRLGLLLGEGAAPPSSASRTPRAASSHTSFSSLSASSEVNTTTSNNTSPVSTLNGSSEAELRLPGARDPSVESMNSLLSHGAVSSNASASPTTTPRRHSVTTSQPGQVEELSLFGRRRSSVRRSARSAHVKGPIDPKVRFASYRGAQLSLRPLFFEVPQQDPDPLFVGRAWLYREIEAHITADAPTNRGVVITGIVGAGKTAAILQLVEYSCFGRKRDESIYQDPYSKSGGYSRMSLIPEGIKSLASRIVAYHFCQAENSVTCLVPDFVHSVAAQLCQAPQLHAYRDLLLAEPQTQALLALPACVSDPSAALVKGVLEPLHNLRRLGKIGADPLIIVVDGLCEAEYHRPDHADTLASFLARHAVKLPSFIKLVVSVRSQLADLTRLLPFHRISLDPDQRADPAADMPTRDLSDYVGFRCMHSPTIRSNITVTQGKIEGSSQHRFTQHVVAQSKGSMLFIKLILDLIERGHLVMKSGSFKVLPQSLSEIFMLLFNLRFPSVRSFEKVEPILNVVLASLNPLTLPEIYHSVNAGLLYKFLSWDEFLSRFKVLNSFLVKRLDDTFMLFHPALREWLARRAEGEPAKFVCDVRAGHADLALRMSRLEWPLDPEASLELGHHILKAHVYKNMARSLPLSPRDLQALWLAQSSHNVSQALACTRNLYSPNTKVSRLLLLAGASPDYPSEHLHNSPIMGVCAYQGHTEMVALLIEFGADVTLTNSEGVTALGLAASRGHCDVVRLLVQAGASLTAKDRQNMTPMVQAAAAGHLNVVGYLLSCDWPGPDDLLKNQAHQALVAAASNGHNNVVEFLLDMAEVSVDGEDNVTGETALTVAAGAGHTALVAALLRAGASITKANSRGSSPLTSAVRNGHYEVAKLLLSQGVAVESPDAGGRTPLMVAASEGHLGLMELLISRGASITRTDREGLTPLGWACLRGHVHAVQYLADCNADLNHADKSGRTPLDLAAYQGDPIVVQFLLDRGSLIEHVDINGMRPLDRAISARNAAAVQCFLRRGAKLGPATWAMAAGKPNILVMLLNKLQEDGVALCRKGRLKEAAHRFSYALRKLPTGDQGEHTATFTHLRLHLTLNLSRCKRKMNEIEEAIQLADSALKMKSDSYEAYYARARAKREAKRLQEALEDVNEAVKLAPQTRDVRRVLIKIRDEMQNELDSCVSIDLAQLRQLAASVDTLSEADLPMTSSILSESGYSSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBR9</accession>
    <name>A0A3R7PBR9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ligand-gated ion channel 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001007">
        <property type="protein sequence ID" value="ROT81162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBR9"/>
    <dbReference type="STRING" id="6689.A0A3R7PBR9"/>
    <dbReference type="OrthoDB" id="442503at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="2">
        <location>
            <begin position="43"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="133" mass="14966" checksum="337F295FEA564998" modified="2019-04-10" version="1" fragment="single">MGRERKVGRGGASSMELHDRTLSSSSDVVVRFRRRYGFAILTVYTPSSFFVCIAYLTTFFPVSNLQVRVIIALTAMLVLTTLLNQVSAQLPRNSYFKALDMWMFGAIGLIFSILILQTVVDVVHRKAQENVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-10-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF75</accession>
    <name>A0A3R7PF75_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative polycystin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012167</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002544">
        <property type="protein sequence ID" value="ROT69622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005261">
        <property type="term" value="F:monoatomic cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006816">
        <property type="term" value="P:calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00146">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46730:SF1">
        <property type="entry name" value="PLAT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46730">
        <property type="entry name" value="POLYCYSTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00801">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="PKD domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="274"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="385"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="460"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="572"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="760"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="870"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1453"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1478" mass="158392" checksum="035E2A72B1AA6032" modified="2019-04-10" version="1" fragment="single">MTVHRLNVSGRYELLLKLTWDAQEESFRDYLWVLRPLTSDHPKVVAPPVVVAPPGEVNVSLTLSDPVELPTLVMANVSWGDLLPPDVINLTQATQPGSKVNHTQILGHTYEESGEFLTTLVLYNGVSSVDLSFTVTVIPRLTLANVTVTQDGVSAHTYSAGVSTLFTITVERGDANTFFLTIGNKTVNSSAPVLSYTFTKAGTYEVTVGGNGPAGTATPLQLSVKVARALSLDDVTLLGVPDVVVAPPGQTSFTLKLTATDELPTSVSGEVIWGDGESTLVDLVQDTPPGQAGTVTKNLTHTYLRSGSFQVNVSLANAVSEVMLVERLRVIDHITLDTILVNYVNEMDSPSIGLSTEAFIKTGVQVNFTAVVNSGQADLFTLEVDGETLTNTEASIVYTFDSAGNYTVSMTASGAAGVPVRRSNVLLTLPDRVVAPPGNAIVNMSVVAADELPTLATGFITWGDSEPDTPFDLTQDTPQGATGSVSLTFAHVYASSGSYQVTLQVANPVSRVNVTKTLRVLDQLTLDKILTSYANEADLPPWYTSVFKVDSPVNITALENNGETASFTLEVDGSSFTSADPSFVYTFTAAGHYNITMTSSGEAGVSSAVVSSVEVAREIKEENIQILLPDKVVWPPAETTVSVTVLAPGELPTHVEGVISWGDEQDEDMFELLDETAPGSIGAVTVNVTHNFSRPGDFLITAFMRNPVSLVNISREIHILDHLTLQKILVEYQDPSDAPPWSSDVFKTGVLLNFTAVVASGDPAGFTLFAGDSILSQEGPSVTYSFAAAGEYTVNMTCSGEAGVSPPVPLTVTLARPIEPEQLDLLLPALVVWPKEEASVEVVLTDAAELPTFVAGTLTWGDSGADADLDLSDVTSPGASGSVSRTLTHNYTQPGEYEVTVSLRNLVSQASLTKTLLVLDHLTLDGISVEYENPADRPEGGADDVFKAGVALNLTALVDSGEAESFTFSVNEETLTSSSATIVYVFPVAGDYVVTVRTKGDAGISNALSKTVRVARAIYEENLELLLPELVVSPPGDVTISASVRSEGELPTNVTGRLSWGDESDSLEVDLVQATVPGSTGSVSRELNHTYEAPGEYEVTWHLSNAVSEMNIRKKLSVLQRIELQELLVTYANPEEDLASPPGFFFLGEVLSIRPRSVEGHAASYVLSASGLEDVEQETPVFNITFDRESDYRVSLRGEGPAGASAELSVWVRVRRRVSGLELVLPSSETRVGLEVVFEVESPELLGACLSLDTGDGRLVGWKPPGKCEGGEDGEEEWEEAPLRPSVKLAHEYALAGRFTATARLFSVMGEAVRRVNVTVWESLPCDTLSVWIRKNGTLDSPVNITRAEKLRVESFVVVNCSVPEIEMEITWRMTRVNDSVEVDLSHIDTSKGVLFLPVRTLHYGLYRALVSYNVSMTNPSGADVWAEVFGESVVRVGKSDLMVVMVQGGRPRSAGGRCRRSTSGRERCPTIRLSGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGY3</accession>
    <name>A0A3R7PGY3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cullin-5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_015827</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 11">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002983">
        <property type="protein sequence ID" value="ROT66175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGY3"/>
    <dbReference type="STRING" id="6689.A0A3R7PGY3"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000142">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000009">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000014">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000017">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.130:FF:000004">
        <property type="entry name" value="Cullin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Cullin family profile" evidence="12">
        <location>
            <begin position="401"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT66175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="778" mass="90351" checksum="5C422851B0999DDB" modified="2019-04-10" version="1">MGSLWQDKGTVSFEEKWPAMRPTVLKLLRQECVSRAEWQDLFWAVHKVCLWDEKGPPKVQKALQDDILDFITHAQARVLDQHEDQALLKAYISEWRKFFQQCNYLPLPFNQLESALAGKTTTSVSKKVQNDDSIVRKLMLDSWNASIFSNIKQRLQDSAMKLVHAERNGEAFDSQLVIGVRESYVNLCSNSGDKLQIYRENFEKAYIEATKAFYRVKAPQYLEANGVQNYMKYAELKLREEEQRGEKYLESFSGSLQNLNECCVEVLVTIFRDTILAECPQMIKNNETDKLQLMFKLMDRVPDGIQPMLDALEEHIVSAGLADMVAAADSITQDSEQYVEKLLDLFQRFSKLVTEAFNEDPRFLTARDKAYKQVVNDTQVFKLELPSKTKGIGNKTQPESKCPELLANYCDMLLRKTPLSKRLTADDIESKLKDVLLVLKYVSNKDVFMRYHKAHLTRRLILDTSADSEKEENMVEWLREVGMPADFVNKLARMFQDIKVSEDLNQQFKESIRTTTKSSVADNLNIKILNAGAWARGSDRVTVSLPMELEDFIPEVEDFYRKKHSGRKLLWHHHMSNGTITFCNNMGRFDLDVTTFQMAVMFAWNQRIHDKISFDNLRLATELPDPELRRTLWSLVAFPKMKRQVLSFSGEVSSPKDFTENTLFWVNQEFAPIKNGKPQKRGKVNLIGRLQLSTEKSKEEDNEGIVQLRILRTQEAIVKILKMRKRISNAQLQTELVEMLKNMFLPSKKLIKEQLEWLIEHKYMKRDDENINIFIYMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHS5</accession>
    <name>A0A3R7PHS5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ras-associating domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002179">
        <property type="protein sequence ID" value="ROT72306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHS5"/>
    <dbReference type="OrthoDB" id="3908708at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045742">
        <property type="term" value="P:positive regulation of epidermal growth factor receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045743">
        <property type="term" value="P:positive regulation of fibroblast growth factor receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17043">
        <property type="entry name" value="RA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21298">
        <property type="entry name" value="GH01721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21298:SF2">
        <property type="entry name" value="GH01721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-associating" evidence="2">
        <location>
            <begin position="371"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="2">
        <location>
            <begin position="465"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="732" mass="80199" checksum="4BBA802F3C6FF763" modified="2019-04-10" version="1">MLKHVGHHRTSSATIKSPCSLPPEERSPFKSPSFASAHEDSFTCNRTRCGAESTPSGSPPCSRMLYSKDNLSSGTPSRESSPSSSPSFSRLRVLDAASRSSSHLGTQAIGNHSSSKSVSCTRIQFSVNSSPSRTNSRIQLPPEDSPSKDSSCSRAKHPSNPSAASSPSQSPVPSLVHPSRDSPKDLDDEVKHQRDSSPSESKGHEDSSSLRTQSPVENSPSEVPSRETTTSTLRPQPSSTPPSAPKSPAAEKTPLRAGTHSCCISSVCFRWRRSPQEMDAPSPEPARKPVAPGTAETDSTSAATSSSEDPQCAETFALYDEAVERPMTLPRRAHRNSVGKASKARLLNKSYCNLHTPCKLSASREQTMSPVKVYMRNMKPDIKYTTMNLSSSTTCRELVVMLLAKFRLRHRDPNLFYVRMEVVVRSPGGDAPARRLLVLDDHACPAELQQCRPRGEARFSVGVRRGGLLRVHDSILMPGSQYKSLLVSYRTTAEELVQLLLNCYSSKENPKNYAVHEVNKNPYSDRLLDPDEFPLLAQSEWPRASRHNYAFVLRRNMSRNVFLRAKTTWRHSLAQSSTDTESDPEDHGAISVMNSFQNMLKRTAISDPLSVLTGPSGDLYSPSSSFMLSRKPSLTFSTKVSPEPNADADLRVIVSPSETNVLSCTSQPCEDLHVAPRHSPTKESASCDIVSISSTKGTYITIPDAKASTSQPHESLRSLDKQYTSDESSFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIQ7</accession>
    <name>A0A3R7PIQ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Notch-regulated ankyrin repeat-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_008393</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the NRARP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002057">
        <property type="protein sequence ID" value="ROT73165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIQ7"/>
    <dbReference type="STRING" id="6689.A0A3R7PIQ7"/>
    <dbReference type="OrthoDB" id="5314041at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004857">
        <property type="term" value="F:enzyme inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019208">
        <property type="term" value="F:phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051226">
        <property type="entry name" value="PP1_Regulatory_Subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24179:SF21">
        <property type="entry name" value="MYOSIN BINDING SUBUNIT, ISOFORM O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24179">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="35"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT73165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="364" mass="39320" checksum="1CE8F0A6B2B2F9AC" modified="2019-04-10" version="1">MFTFVIFWSCVDLFSSCDSSIRIFLRRRQRAACKSQRGRRVVRNQSPAPAASTRPRAPPKVTCSASENPGTTAEPPLPPRPSSPRVSGRCPDEAARTPALAMKVERASSVCSDDAPSSPDSVILQLPRQPRVTSARLADFGFQFTPAPPGYGDVEQFGCQAEFVRAVLDGNPRELKRILTRYSQLVQINGFTADGQTALTQSCMDGNLEVIKVLVAHGASLHLTNRDGFSPLHLACWRGKPDVMEYLLHSASSRRVTAAILHHVTVCDVGTGREGRGGRGGRPPPPTSSSTYYSPRDPLDGGPRSLPPPLRRHYESWRSGTGAGEARAEGPIYPGPPQNSRGPSRHDGDVIIGPPSPADPHPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ24</accession>
    <name>A0A3R7PJ24_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ24"/>
    <dbReference type="OrthoDB" id="6356350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF435">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12532" checksum="B5CD036EE382A078" modified="2019-04-10" version="1">MAEAGIIERSNSPWYSPVVLVTKKDGSKRFCVDYRALNPVTATDAFPLPRIDDTLDALSKVQWFSTLDLKSRYHQVEVAEVDKENAFSFGQGLWHFNVMPFRLCNARGCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQQ0</accession>
    <name>A0A3R7PQQ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">U1 small nuclear ribonucleoprotein 70 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001627</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001210">
        <property type="protein sequence ID" value="ROT79647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQQ0"/>
    <dbReference type="STRING" id="6689.A0A3R7PQQ0"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001585">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="106"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00058765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="297" mass="35663" checksum="66B38AF40562BBAA" modified="2019-04-10" version="1">MAFVDGIKDLWEVTLLDLFPFTGESPLNLTSPYSLSHSPALLYHTDICSHFVSRLLLLPYLSHYYLCLLFPSTAAYKHADGKKIDNRRVLVDVERARTVKGWLPRRLGGGLGGTRRGGPDVNIKHSGREDDRRRGGGRDEERMESADRDRERDRDRERGSERRRSRSRDRDRDRERRRRSRSRDRKRRRSRSRERGMPEEGEEREKRRHRSRSRDRKRRSRSRDRKHRRDRDRERRERVPGEEVEEGVVKIKQEPEDDYPDYGSNYYNNYPMKDEEERAKNGTKYEEEEEANNEIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVD2</accession>
    <name>A0A3R7PVD2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">2-hydroxyacyl-CoA lyase</fullName>
            <ecNumber evidence="9">4.1.2.63</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023102</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2-hydroxyoctadecanoyl-CoA = heptadecanal + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:55196"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:74116"/>
            <dbReference type="ChEBI" id="CHEBI:138631"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:55197"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 2-hydroxy-3-methyl fatty acyl-CoA = a 2-methyl-branched fatty aldehyde + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:25375"/>
            <dbReference type="ChEBI" id="CHEBI:49188"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:58783"/>
            <dbReference type="EC" id="4.1.2.63"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25376"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>an (R)-2-hydroxy-long-chain-fatty acyl-CoA = a long-chain fatty aldehyde + formyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:67444"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:170012"/>
            <dbReference type="EC" id="4.1.2.63"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:67445"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.63" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01000642">
        <property type="protein sequence ID" value="ROT83717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVD2"/>
    <dbReference type="STRING" id="6689.A0A3R7PVD2"/>
    <dbReference type="OrthoDB" id="16262at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106359">
        <property type="term" value="F:2-hydroxyacyl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001561">
        <property type="term" value="P:fatty acid alpha-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02004">
        <property type="entry name" value="TPP_BZL_OCoD_HPCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07035">
        <property type="entry name" value="TPP_PYR_POX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000027">
        <property type="entry name" value="2-hydroxyacyl-CoA lyase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000038">
        <property type="entry name" value="2-hydroxyacyl-CoA lyase 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045025">
        <property type="entry name" value="HACL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710">
        <property type="entry name" value="2-HYDROXYACYL-COA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710:SF2">
        <property type="entry name" value="2-HYDROXYACYL-COA LYASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme N-terminal TPP-binding" evidence="15">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme central" evidence="13">
        <location>
            <begin position="195"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="14">
        <location>
            <begin position="377"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="557" mass="59870" checksum="EA64CC199D222BEF" modified="2019-04-10" version="1">MADEETDGAHILVNALVDQGVEYMFGIVGIPVVEVAVAAQQAGIKYIGMRNEQAACYAAQAIGYLTGRPGVCLVVSGPGLLHAIGGMANAQSNAWPVLVVGGSSDQDQEGCGAFQECPQVEACRLYCKYSARPPRLDTIPYHVAKAIKSTTYGRPGAAYLDFPGNLLNEKTSEDSIQPFPRNPLPPVSLACPEKISEAVALLAGAKRPLVVVGKGAAYARAEDQVRALIEKTGLPFLPTPMGKGVVADDHPQCVAAARSRALLEADVILLLGARLNWMLHFGRPPRFAPGVNSNSVPASVALLGDLKPVCVQLLKEVSGRLISHDSPWWARLDEKAQANMQINRAMAEDISVPLNYYAVFSHLQQLLPSDCIIVSEGANTMDIGRTFLLNRLARHRLDAGTFGTMGVGLGFAIAAALYARDHAPGQRVVCVEGDSAFGFSGMELETIYRYNLPIVVIIINNNGIYGGLDKELFQDIRDGVDVTLATPPTSLLPSARYERMASIFNESGHLCTTIPELESAVNLSLAESQKPSLINVLINPMAQRKAQDFDWLTRSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZV4</accession>
    <name>A0A3R7PZV4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative HORMA domain-containing protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_017178</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003173">
        <property type="protein sequence ID" value="ROT64878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZV4"/>
    <dbReference type="STRING" id="6689.A0A3R7PZV4"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HORMA" evidence="10">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="209"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="578"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="807"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="297"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="578"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="818"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT64878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="828" mass="90575" checksum="E057C113B8B55DB5" modified="2019-04-10" version="1">MSLFSPPPPHTPRPPAISSSLSLNASSSSALGLPTLSPRNPHLSLSLSPLSLSLSLSSLSRLSLSLSLSLSLSLLLSSLSYLKALESYTYKIWYSDNKEAFISELVTNIDSVEKKHDVRRSTQKMLRTVLLLTQSLKPLPSKVFVTMQLHYYDNVTPPEYEPVGFKAAASTDSHSFGDPVTIKVGDVSTPFHTVKLRVTVNKAVYSDDKEENVLQDQTGHDNKENPHEVNEQAESTVLENAEDPLPSSDPVIIRCHKRSTKPLATLGPQSGHKPQESLTPKDEQTSSMCLEKDKQDSTGADPQLQSESTPQDDCVPSITPVSKTCTVAQVVSIGSGEEMQIVPEVEPKEEQEGCTSVRRSRRLLSHSSAVTPTASGQGLSGTSTMKDEEPVRCECGVHHDDGLMILCDVCKTWQHALCFKLSKKEEIPEQHVCLQCSVTSGLPCTDSSFRDMRKKKVQQICLIRRALEFLRGYHARVSVAKLAQRLGVDISKARKLMSHLEAMMVFEGKGKRHRVVNKTKIASTYLEYFGSQPVLMEGEEFEDTQVFQTPKQVSQEVGWDSDMTPDINLPTQVLDSEMESLQDTPTPDSQATQVVADTDSQKTTQFIRKSEGERLLSTYPGEVVDSTQDVPVGTQKITLGTGLDESFSIYSPAGASQAFATAGNTVATLGEEVEEMTDICSNPVDSTTLADADTVQVSKSSCNETSVTNTFVTEPANTSQEHTTENPGKSAALIFESADIQKSAGGSDLQENQSQVNNENLQEVACRSVELHVENPASRRALMTRSNRLSRNKAKMAVTVSLNDFEISSSQGSPTQEHHRKGKRAKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3M8</accession>
    <name>A0A3R7Q3M8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002775">
        <property type="protein sequence ID" value="ROT67698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3M8"/>
    <dbReference type="STRING" id="6689.A0A3R7Q3M8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="744" mass="79527" checksum="DF36FFA2C4689533" modified="2019-04-10" version="1">MSAAAVAWASLQDAHHHHETPGQESEPPTGSSQHSAHAHHRLHDPSHTSHGTGQNFLENPQLSLLEKSPSLPSFSFSEGSQNPLPSPNDVSVLPVPVQVDSAPQRKADPSPVPLLSPLSQNPTSLAQLMSSLKQNPSALAELLSALKQNPSVAPNFLSTLRQNPSAAAVLISSLRENPSVASQIFSVLNQNPSIAAQIPSVVKQDPSLPSQTPPTLRQDPSATSQAQSIPEENPSTLPKDLIPSTLKVEPSLPPVQLLSARKDDPSAPSRFLSTLKPKPSPTPLASPLTQNPSNPLPVLSAVTPRSFVRSTPSPPQFQPTLIPPSPPQFQPTPIRPSLPQFQPTPIPTSPPAQFSTTQNSPSPSKFSSHPIQFASSRPKFSPIVTQPTPSASETPSTQFTSSPSKVVSPATQFISPPSTFSSPKSFSSTPKFTSPNSKFPTSSKQFVSASSKSLSSTNPFASSPSETSFSANQFSPSPSQFSSAAIQHSTSSKQFSSSSKQLSSSQFSSSPSQSSSSSKLLSSSPSQFSSFPSQSSFPATQFSPSPTQFPSPQVQVRSPPPRTSPSSSAPRTPSPPSYPRNRSPSAFSQNPSPSLSPRNTPSPSLSPRNTPSPTLSPGNPRSPSQYPSGPVEYSFQWDVNDPRSGNFYGHQEERQDVDTRGSLPKISKKVRTTRRRSQDQTKIPHRPVPDLSKALNSDQDQTEATHRLEDVVKVSSRAFPVSLRSSPFLYNKGHTSDCLSLYLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q539</accession>
    <name>A0A3R7Q539_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_013029</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002630">
        <property type="protein sequence ID" value="ROT68828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7Q539"/>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12881">
        <property type="entry name" value="SPRY_HERC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.920:FF:000015">
        <property type="entry name" value="LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HERC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000006">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035768">
        <property type="entry name" value="SPRY_HERC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF6">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HERC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="14">
        <location>
            <begin position="20"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="1390"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="1943"/>
            <end position="1991"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="1992"/>
            <end position="2046"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="2047"/>
            <end position="2098"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="2099"/>
            <end position="2150"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="2152"/>
            <end position="2203"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="2204"/>
            <end position="2255"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="12">
        <location>
            <begin position="2256"/>
            <end position="2307"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="15">
        <location>
            <begin position="2443"/>
            <end position="2790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="266"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="508"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="866"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1060"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1665"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="297"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="520"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="866"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="1065"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1077"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1665"/>
            <end position="1677"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="2753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT68828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2804" mass="303973" checksum="BFF1A9DCCC3A5164" modified="2019-04-10" version="1">MWVIPSAQAHLKASQLLMELQRHLVRLSSPDLLDEQSRPESPDDNLPVQEVGFDPDKSVCCSVEGGHTLVHGPGGRGYGLGSTPITSGCYQWKFLIVKENRGNEGTCVGVSKYPVRDYSHRTSSDMWLYRAYSGNLYHNGELSISLPSFTQGDYITVVLDMEARTLSFGKNGEEPRLAFENIDATELYPCVMFYSTNPGEKVKMVDMQVRGSPRDLDPGDPLCAPQAAVLAEAHIALLRQLHEAPIWTQQVNDCIIERLNQTKELIPQPKDVPESVETVSKSESDTEDPTFDFEPLVNTSEVQTSRETSREDLVLTLDERLEQEERTKKKTGSCSDDDDRNTPRATPRSGSDSISQEKKTLKGKSCKQNLVYEMNLEQLCKEVYPALAMIGGVDSGLRVGGQCVQKGTGRRAMVLGALRQGHPAVKVQWCDWDTSISDVPVSFLEPVEPPPFDVSKMTGITAQVITQIMRLAGLTQEIEFPKVTYNHETDEVHTSSTGSLISPHLPQAHEEAKSQNAVNSSGPSHSPSPRKGSRGSGDGLTMELLTDQLVTNIMDEVTGRSVEVPEQQEPVVPTQKDSPQTGELAVEEGMALRLAFLQSASLRAICAIMNCTRYAEMLLVPKAAQEKDGGEKGSSVSLLHEEDEIRTAIRVLVRHLVSACTLAQPLKRQVSVAEVERSHLVLHSMCMRAWAEDSLSVADTQSRIMALTANEERVTDQIVEATERPQSIITELPTTGTDVRAPKRPIPSLGVTLSFPPLTPLPPLPPPIATPLLEMGFSLKHIQKAIAAQGHKGEPSAAQINQLVTWMLEHPCIDASETSERRRSHDDTSSSSVAAAAAQLIERSDIQDLSGRRMILRRGGCVDLRSSVVPSRPSGRGLDTRDTESSRQMQHGRSEPTRFRYGGVGFEDQLRGSDDSIGTLPNDLDQWLCGSVATNNDGDRTLSICEVCHHATSNLRQHMRVAHPGCARPWMAGVCGTLIGGTYILCEVCQEQHAGGSSSIGGSGGSGDGQDRLRDLTTVLAPDLAPAPLATMEDDGLSMNEIDLKMTNYSVIASRLGLTDRRPIPDPMPFPRPDPLGSTTLVSNIGESPEATNTSGARPRDSNITAVPDRSLGEQAAALTSPIARISALRRTTHALRVTIARAVVMRALSLLALSGGSCDLWAGLNALGLCDVRLLVRLMWLVAQGRVPLDGSARTTGAVLQPTDITTSLAHLSDAIGALAQNDTDAAKLLLHLCTQHLMVAAMGMSSGDIVGGSGEEDVDVTLCEERRGCQNASAMHQTSFPVTQALVSLLAANSSLIHLAGKGEAVTSPVTASGGQGDPGIQLANALAACILSTRLPHSHRQWAATQLVECIGGRAQLAEHCSDFPGPNISSAADFTGALPRVPTSYLEGHTACASRALWMPGKNLLVTSGHDGSVRTWKVSQRSHACQEHTLVFQQDENDSNYSVNPPAIEHVVALPTGRHIAASSENVLNIWPLNSSTLASWTSSSIITALEAPLHGVCDLMITGHHDGSVTLAAFTASGIIPNPIRHAGRQDVYVSCLAWHDQDKDLAVGFSDGVVRVCSVQSDVGSVTVQAQQGPVQCLEWSSNCCLLASCGEGGTKVWTQTSSGWTPVYSLDYKSLPLCIKWSPVISGVLEGECTHMLVVGHEDGLVTVWVVPQSPSASGDSEYRGSSQHGEGAESCDPRCQLQLRGHQSPVTSLAISTSGLMLATGCQKSMNGMVNVWSLQEGSLLQTLVGSGGINALVWCGTSGLAICVSRSQNVVFTALSDDQFFKLRIPAFCRTRLHTWGMTGLHQAPCLRALLSHLPSLLLSQYQHEKPMVSSGEQLVHSRYLQQLCSLALLLRLDCILCTQPAPVHVTRPESVVEWNWLETLCTAVSTAESLKKRTPLPRPFTTQLLKHSDDKEHLNYAIENGKWDVEQDAAVMSWATHHPGDWQVGGRCQVYMWGSGRHGQLAETGRSSLAPVLTESLGCAQQVVCGQNCTFIVTANGSILACGEGSYGRLGQGNSDDLHTPSVISTLQGFVVTQVATSCGSDGHSLAVTDSGEVFSWGDGDYGKLGHGNSDRQRRPRQIEAFQGQEVVQLACGFKHTAVVTSDGKLFTFGNGDYGRLGLGSTANKKLPERVTALDGWRIGQVACGLNHTVCIDIDGNTVWAFGDGDYGKLGLGNSTSKSTPQKVEAMCGIGIKKVCCGTQFTVFLTKDGRVYTCGMDRLIGQPESRTRGHNRPQQVPALVTHVVVEIAVGSEHTLALANNGDVYGWGVNSDGQLGLGHTAAVREPQLIWTLSGKGIRQISAGRSHSAAWSALPLPPVTPGTPAPMQLGIPVSVPPQYPNLQNIPPGALCSRLRMLHQFSDLLYASWKLIPLTPGLECYIENVSAVTCAAVRSLVSPRVYTLPLVRCLGRTMVQGRNYGPQVTVKRISTRGAPCKPIFIQLARQVVKLKPSDLRLPSRAWKVKLVGEGADDAGGVFDDTMTEMCHELVTGGVPLLIPTPNAVSDAGNNRDRFLLNPDLTQHHHLLWFKFLGILFGIAIRTKKPLALPLAPLVWKLLAGVPPSSSDLEEVDIEYMQSLRAIRDIDQDGVTEDTFHDVIPLESFECTSMTGARVAVVPGGRAVPLTFTNRQEYVNRTIYYRLHQMDRQVAAVREGMAWIIPVPLLSLMTAAHLEQLVCGLPHISVATLKKVVRYREVDENDPLVVWLWHILESFSPCERVLFVRFVSGRSRLPANLADLSQRFQVMRVDRPIDSLPTAQTCFFQLRLPPYSSQEVMAEKMRYAINNCRSIDMDNYMLARNQDPNHHSDDDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCE2</accession>
    <name>A0A3R7QCE2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-catenin-interacting ICAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007124</name>
        <name evidence="5" type="ORF">C7M84_024876</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTNNBIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001906">
        <property type="protein sequence ID" value="ROT74381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01000901">
        <property type="protein sequence ID" value="ROT81966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCE2"/>
    <dbReference type="STRING" id="6689.A0A3R7QCE2"/>
    <dbReference type="OrthoDB" id="10262856at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.490">
        <property type="entry name" value="Beta-catenin-interacting ICAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009428">
        <property type="entry name" value="ICAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036911">
        <property type="entry name" value="ICAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040065">
        <property type="entry name" value="LZIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16505">
        <property type="entry name" value="PROTEIN LZIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16505:SF8">
        <property type="entry name" value="PROTEIN LZIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06384">
        <property type="entry name" value="ICAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81730">
        <property type="entry name" value="beta-catenin-interacting protein ICAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-catenin-interacting ICAT" evidence="3">
        <location>
            <begin position="113"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT81966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="21102" checksum="77D73D66003968EF" modified="2019-04-10" version="1">MASRGTTETQKLRQQLEEQLDRLVAQLADLEECKGELDPEEYDEVHKDTIEQLNEFQASLTRMSSGNMTLVDSLSAMQLAIQAAISQAFKTPEVIQMFAKKQPDQLREKLFQIERDQKIGKLTMDSYTQQKLEILSALQKLGETLEEGEQSFLDAHASSLMKNFDQVTDDEGSTQKVLEMARQGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QD59</accession>
    <name>A0A3R7QD59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative fibril-forming collagen alpha chain-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003376">
        <property type="protein sequence ID" value="ROT63797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QD59"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="51308" checksum="027949E2A743DA82" modified="2019-04-10" version="1">MLIQTLQYKRLLNDPVCRRSLASAYIIFFPRGQLSFVRVSAPCVSVICQRHLSAPPVRATCCNRKGGVGEREWRLGERVEGWGGRGEGWGERGGGLGRESGGLGERVEGWGERVEGWREEGGVGEREWRVGERDGGLEGESEGWGERGGFGGERVEGWGERVEGLGRESEREWRVGEREEGGFWGERVEVGERRGGGLGRESGGLGRESEGWGERGEGWGERVEGWRERGGWGERVRVWGERVEGLEEREGWEREWRVGGERRGEVGRESGGWGEREGWGERVRVGEREWRVGGRERLGKRGRVWGERVGWGRERVGEVELEGESGGLEREWRVWGERVEVGGEREGWRRESGGLGRESGGLGRERRRERVRVGERVGGWEREWRWRGERVWGRESGGLGRESGGWGERERVGEGEWRVGEREWRVGEREWRVGEREWRVWRREREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFS8</accession>
    <name>A0A3R7QFS8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015951</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002996">
        <property type="protein sequence ID" value="ROT66056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFS8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="642"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="653" mass="70222" checksum="54F12A812A518CAD" modified="2019-04-10" version="1">MATRMATFSSFTTRHSLPSTIPPSPPPPSLLPIHLPSPPTFPSPIQHPSPFTPPHLPFSSISPPPFPSLPSTLPSPHFPSPHPPLPSPPTFPLPHPPPPPLTHLPFPHPPLPFLPSPIHPFPSPPTFPSPPSTPPFTLPPFPFLPHPPSLHPPPSLLSIHPSLPSSHSTPSLHPNKLTSPPSTTPFTKIEPHLPFSPIHPSLHPHLPFSPIHPFPSSLHPPSPSPHPTPAYARPPHLHLPFFPHPPLPFTFPPSLLPIHSLPFHPPTFPFSPSTSSLFSPTTLLPPHLPFPPSTLLTSHLPFSPITPPLTPPPHRSPKPPSTTLTHLPFPPNPPSPSLSLTSYPHPYSPIHPSLHSHLPSPPHPPSLHPLSLLPIHPSLPFSPSTLPFTPTFPSPQSTPPLHLPPSLLPHPPSLHPPPSLLPHPPLPSLSSPIHPPSNPHPSLSPPIHPFPSPNPPPFSPSTPPLHHFLPPIPPLPSLLSHPPLPSPPTSFSPIHPSLHPHHLPFSPSTPPFPPPTFPFSPIHPPRPPFSQIPLPSPHLPFLSHSTPPFTPNLPFSPIQPLPITPRNLPFSPIPPLPSPPPSLLPSTPPFTPHPSLLPYPPSFLHPPHLFSSPPSTPPSVVPHPTPPFLPPPSLRPRPAAPSLPSAASSNTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGL3</accession>
    <name>A0A3R7QGL3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Distal-less</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_003051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001410">
        <property type="protein sequence ID" value="ROT78232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGL3"/>
    <dbReference type="STRING" id="6689.A0A3R7QGL3"/>
    <dbReference type="OrthoDB" id="6375979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050460">
        <property type="entry name" value="Distal-less_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24327">
        <property type="entry name" value="HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24327:SF81">
        <property type="entry name" value="HOMEOTIC PROTEIN DISTAL-LESS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="92"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT78232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="137" mass="15216" checksum="3BCCC3DD01A754D2" modified="2019-04-10" version="1" fragment="single">MPDQDLASKYMDLPQQGLASMAHTPPYAQPLGYQQAPTPGYNPPGYGFPPMYPQSSYPGYPMSSYLTSQCPSPSVDEKPEDEATVRVGGKGKKMRKPRTIYSSLQLQQLNKIFQRTQYLSLPERAELAAKLGLTQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHJ4</accession>
    <name>A0A3R7QHJ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Antimicrobial peptide type 2 IIb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHJ4"/>
    <dbReference type="OrthoDB" id="6358465at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00199">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="216"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="351" mass="37028" checksum="8AAFF3D962908C1E" modified="2019-04-10" version="1">MDPFGSRDQVRDPFLEENVSSSSHGISSSHLHSCRGYIKGGFVYPDTTFSTLEDDGWRQEVFGSGTSGVSAQWLSRPTRGTMVARAAMVREASSRVEASAEATGAQEASAEATGAQEASGAQEASAEAKLRRLRRRRWGRPWRRKCVGIVGGHGGGSVGIVGGGFGGHGGGSVAIVGGGSGGGYGGGSGASCRAWCKTPQNQAYCCEDSSEPITIPVVKPGSCPPVRPQCPPVRSGYRPPNQCSNDSKCPGYEKCCYDTCLKHHTCKAPGSTCKVKAATEQEQCPRRCARFQVSFSPSISRPPYMPSQHIASLAIPAASVLLLARTVLDLFHVSVSDSQTTSTSAISHDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKJ5</accession>
    <name>A0A3R7QKJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025044</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000916">
        <property type="protein sequence ID" value="ROT81782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKJ5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="43657" checksum="98E888F0634ACC56" modified="2019-04-10" version="1">MGGIKRDRKGERKREGEKDMKPESLHGKGSHSCQVDIFTRSHVPGGRLHRKGWSLLSYPSSSSFLHAQTSISAVSPFRLFLSFRPLPFPLSLHPLFPSIPFSFFSLPSLFPLLYFRPSSLFLSSHPLFLSLLSSLFSSSLPSIIPLILALVPLPSLLPPSSSLLYFRPSSLSLFPFSLHLSSLSLSSPLYLPFPLPLFLALFPLPSHSLHVLTFSPSPSIFLALVHYLPLSPSSFLPSPLFFGPLPFSPSLPLPLFPSLFIFSPLPHSPLPLPALHLRSLFPLYTSYLIFWPSSLSFPPSTSSSSISFLSSRITSPTSFPSISSASIPYDPISHQTTTANRLPSVVAFTVQVMYEDITFSFLKFSLFLFPSSLIFLLFVPHNLIWMGGLCRIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKZ7</accession>
    <name>A0A3R7QKZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000860">
        <property type="protein sequence ID" value="ROT82202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKZ7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="41024" checksum="0AE96E664746C684" modified="2019-04-10" version="1">MFIQDRRIGGGVEGAWWGCGVVKGFSSPLSAFTHLAGLILASLLPSSFLLVPSFYALYVSTHVFMLAPRLSPSPLFPFPFSLSISLYAYFSRFLPLLSFSSSSSLSPFIIPLPLSLLPSFSILSPISPLSLPPLCLSLSPSPSSFSFLSLPFSLDLLLSSPFSFLLLSLFYLTSSSSAFLLLPPSPPFTLLSLTLSFTYSFSSSSLLSTPLFISHLFSRFSPSYYLLLLLFSASIPSPSSSLPPILLPPSPPPPLSLLSYLLLLSSFLPLISSSLPLPYFLSSPLSFLPNSLLSRLSPSFPLPFSFTPPFSSFFHITLFLNSSSSPTPLSQPHTLTPPSLPHTPFLSSSSPTPLSPNLTLLLPPPHLLLPRPPLPSAHSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QL72</accession>
    <name>A0A3R7QL72_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative amiloride-sensitive sodium channel subunit alpha-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_010751</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002367">
        <property type="protein sequence ID" value="ROT70947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QL72"/>
    <dbReference type="STRING" id="6689.A0A3R7QL72"/>
    <dbReference type="OrthoDB" id="10064773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT70947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="277" mass="31730" checksum="C61A4FAED964FCC8" modified="2019-04-10" version="1">MCKQLCLEREYRRRCRCYALFAQEHNDTKNDLGGVDIRCSLFNTTQKVCMKKIAADDLDGVLECDCPLPCRETQYRSQVTSTRANMLHYELLHKLRKNVASFCSDKMDTVVLHVYLDSISYELIDESPTYTWDTLLCNLGGSLGLFVGVSMLSILEVLELLVDLCILTFSQKKRGRKDKKEWNQDEGELVRVQTQGEKNVNFAWVLEGSVGKCSAKCASQTELQVLREELQHLKMAFATHTEEVRAISEAKAARGRHPQENQDLHEAFHTLFMNQKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QL85</accession>
    <name>A0A3R7QL85_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative stress protein DDR48-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000834">
        <property type="protein sequence ID" value="ROT82386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QL85"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018642865" evidence="1">
        <location>
            <begin position="19"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="22119" checksum="E103F943D0E55A29" modified="2019-04-10" version="1">MARTVLAVLAVVLAAVVAEPDYPRPAPCPPKLQYVTKYQTQYQEVPVYQTQYQTQVVPTTRYVTQTQVQYQTQYQTEYVPKYVTQTAYKTQVQYVTQTQVQYQTQYQTQYVTKSEYVPKYVTQTQYQTQYVTQTQYQTQYTTQYAPQYVTETQVQYQTRYTTQYAPQYVTVTQQSYKTVCPKPAYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QSI6</accession>
    <name>A0A3R7QSI6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001628">
        <property type="protein sequence ID" value="ROT76633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QSI6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="40643" checksum="60CBA4394CC22687" modified="2019-04-10" version="1">MTPTSTTSLTSTSTPPPDSNLDPPTPPVTPTSTPLDPTSPPSLPPSHTLNPPPQPNLDPHPLPTSTPSPPTIPSPNLETPPPPPSPHPQTPTSTPPSLPHPQTPPSPPPSDPNLDPPSPPQPRPPFPLPTSSSHPSPPPISPPQTPTSTPHPPTLPPPQPPTPHPLPTLRPQPRPPIPSPPSPPHPRSPPTLPNRQPPPSPHLRPQTSTPIPPHPPHHSLPRPNLDPPPTSPPLRPPQTHLAPPLPTLRPQPRPPSPPQTSDPNLDPPIPSPPSPPQTPTSPPTLSPGPHSTPTPPTLNPNLDPPTLDPQTRRPQSNLDRGPSAHPPISPPQTPTRPPSPPTLRPLETLKTLTPLPLPPLRGPPPDSQTQPDHPSPRVPLPLRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QTR5</accession>
    <name>A0A3R7QTR5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative cytoplasmic protein NCK1 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_003218</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001438">
        <property type="protein sequence ID" value="ROT78073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QTR5"/>
    <dbReference type="STRING" id="6689.A0A3R7QTR5"/>
    <dbReference type="OrthoDB" id="26539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030971">
        <property type="term" value="F:receptor tyrosine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048013">
        <property type="term" value="P:ephrin receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09943">
        <property type="entry name" value="SH2_Nck_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11766">
        <property type="entry name" value="SH3_Nck_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11767">
        <property type="entry name" value="SH3_Nck_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000110">
        <property type="entry name" value="Cytoplasmic protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000027">
        <property type="entry name" value="Cytoplasmic protein nck1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051184">
        <property type="entry name" value="Tyrosine-phos_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19969:SF14">
        <property type="entry name" value="DREADLOCKS, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19969">
        <property type="entry name" value="SH2-SH3 ADAPTOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="1 5" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="47"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="117"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="7">
        <location>
            <begin position="268"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="11"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="236"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT78073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="365" mass="40388" checksum="93B7A3C0A9DA83FA" modified="2019-04-10" version="1">MNFLPDIKKRVKKGGGSRTLPSSGGTPTRGVESPGGVRGGTPIDPSEAIGWAVVKYNYQAQQMDELSLVKGTRVLILEKSNDGWWRGHYNGLVGWFPSNYTTEEPTEEDHTYTLAENVLDVVVALYSFTAQNEHELSFTKGERMEILDRPPSDPEWYRARNTQGQVGLIPKNYVQELHEVVDTRASRSREPSQTRQLPPPGPANSAPPPPHPPATNGGAHNADSHLAQGMQGMNINAAAPNTTAPSMPQPPPVSGVPPDKGHFTTRDWYYGPITRAQCDDVLNQRGHDGDFLIRDSETNVGDFSVSLKAAGRNKHFRVHVENGFYCIGQRKFATLDQLVDHYQRSPIYTSQKGEKLYLIRPLPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SH43</accession>
    <name>A0A3R7SH43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">At-cadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021231</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004415">
        <property type="protein sequence ID" value="ROT61038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SH43"/>
    <dbReference type="OrthoDB" id="6497475at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050174">
        <property type="entry name" value="Protocadherin/Cadherin-CA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24028:SF328">
        <property type="entry name" value="CADHERIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24028">
        <property type="entry name" value="CADHERIN-87A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cadherin" evidence="10">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="105"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="288"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="340"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="404"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="463"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT61038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="551" mass="60938" checksum="7E969FA1976020CE" modified="2019-04-10" version="1">MNENDDTHLIFCLSKVEAWDEDHRDQGRLLYSLRGDGVDGLPPDDAFFAVNPRTGDLIQLRAVDRDPPHGKSVWRLTVEVRDGQPAGQQPDLDDIFLEEEHDLRRRPEGGFHHPGVKVSWGRHDTPTATTTEDNHGGGQGQKPSYLYRTSRASAIDRTQRQVVGRGERDRDKGWLKSKSRGKRRKREESGQNAAADTLLPREPLKIEAAEEAQAEASPSKDPLRSLDEGNVHAQLPAIAANTDSSFLKFLDSESHVTESADWVRSAATTDLGKRDSELVSETLQVLRSSESSAHENILDKRKAKRKTEKKRKDIGKTVQEKREEENKTLFELKYAVANTMHPSSSPLPVDEAPAGLGDRDHTRNSQAAHTPSSSNPVAITGRENFHITNPRRGLGALNQIRTREQNVPGRSRRSEWTKAGLEDDTKAGERHVRNNPHNGAAWDVRAPTMGPYKAFLLEGGGCAHRGGRGSNEREENSRTGSEGDPEETEGGPVHVVETVVTVFVKDINDNAPVFSNTTMFASVQENGAVGEFCFVFCPAHLLHVDNAVFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJB2</accession>
    <name>A0A3R7SJB2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemocyanin subunit L2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003446">
        <property type="protein sequence ID" value="ROT63388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJB2"/>
    <dbReference type="STRING" id="6689.A0A3R7SJB2"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF5">
        <property type="entry name" value="FAT-BODY PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00209">
        <property type="entry name" value="HEMOCYANIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018699902" evidence="1">
        <location>
            <begin position="16"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin middle" evidence="2">
        <location>
            <begin position="116"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="295" mass="33757" checksum="AF0939B968530B8A" modified="2019-04-10" version="1">MKVLVLLALVAAAAAWPGFGFQADAGGVSDAQKQHDVNFLLHKIYGEIRDSNLKAKADSFDPEADLSHYSDDGAAVQKLMRDLKDHRLLEQKHWFSLFNPRQLIHSPLAEHVVLPPLYEVTPHLFTNSEVIEAAYRAKQTQTPGKFQSSFTGTKKNPEQRVAYFGEDIGMNTHHVTWHMEFPFWWQDSYSHHLDRKGENFFWVHHQLTVRFDAERLSNYLDPVGELHWDKPIVQGFAPHTTYKYGGQFPSRPDNVDFEDVDGVARIRDLLIVESRIRDAIAHGYIVDRLAIALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQY0</accession>
    <name>A0A3R7SQY0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_010461</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002325">
        <property type="protein sequence ID" value="ROT71228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQY0"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001732">
        <property type="entry name" value="Zgc:162936"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000264">
        <property type="entry name" value="Zinc finger protein 236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF23">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="540"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT71228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="565" mass="62951" checksum="4CB6A7BB4527DA42" modified="2019-04-10" version="1">MEERSEGLRLWKNKLDDIVSLASQLQPEDHKVAAEIWFAALKQIQTLWSKAQLSPSRECVSELSSLEDVNSLSTRKTTVFQDEEHSNNNATSINISNQTINRRNGKEGRRDMFQQHPLSPSAAKKIKKEHQDPEEEVDEEDLQNVKALVKQEVMNGEESQRNSGDENENEVQSVHLMISADPVLVPNMSKFKKVQKSNASGKTETAYQCEKCPKQYRTPVALYKHRSTHTKNLECQICHQRLSNRHALNGKSGILQAHMLIHTDQYAHLCDVCGRSFRQRSQLITHHLRHEGVRPYSCTECERKFTTKGDMERHMRTHTGERPYHCDVCGSSFARPQTLQEHKNRHYNFKPYVCKICGKSFHELAACSRHVKGQHGREPAAASIIRLNSQNQQADSEETKLITIAEQSVTHAETISRQGSAVTCEGCGTLMSSMAVLKNHARQCKAQAGVSVAEWLVHGSAGSPSSGMEITVGESGASGDLGCVEESSSGLECVKEVDSSGLSHAVTISEDGSITSVPLSQLAPLHLQLENDYMVVLSDDTRAQEATSSFQTQDLQQDDETSHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SR23</accession>
    <name>A0A3R7SR23_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002303">
        <property type="protein sequence ID" value="ROT71368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SR23"/>
    <dbReference type="STRING" id="6689.A0A3R7SR23"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT71368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="601" mass="66182" checksum="76583008D06FEECD" modified="2019-04-10" version="1">MRNLQHPAHSRPWPPHLRPKQQGIKDRQYLYFFHVVSVLTHAPPSPYQSTHLTPPSLPPTHPSSYYCFPTPVYTVNPISSSPYLSHPPDTHLPSFPYPSFPHSFRFLSPPTHDSSSLSHLCPLSLPPQPLVLSRILPRLLAFPPSSSPSFPPIFPPFPPSSLLPRSLFLNVLSFPLFVSPSTLPPLLPLPSPPFFPPFPPRPFFPSPPAFFPPFPLLPLPSPFFPPFPLLSPPFPLPTSPSVPPSPLPCPLFPLSPSALAYPRASPPFLPPPFNPFFPPFPPFLPRLPPSSLPCAPSSPPLPLPSLPSPRLLPLPPSSPPSSPSPDFFDYRYFLFPFFPSFPPLFARSLYPSFTLPSPLFPSFPPLPLLPPLRSSLPSPFVALPFPHSGPSSLLPPPYFPALFPASSPPSPPSSPPPPPFFRSLLTFPPFFPLTFPPPFFSSLPLLLLPRRPPSFPLRLPPFLSPIPLSPSLPPSLPLPSRRFFPLLPPLLSFPSPFPSFPLAFPPFFPSALPPLLPLPSPPSPFFPPTFPPLAFLSPYPPSSPLPRPLLPLLPSFPPSSPPFRPFPPQLFPSPFPPPSSAPLPKHTEFRCARFLIDINSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRT0</accession>
    <name>A0A3R7SRT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative erythroid differentiation-related factor 1-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002194">
        <property type="protein sequence ID" value="ROT72189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7SRT0"/>
    <dbReference type="OrthoDB" id="419432at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056582">
        <property type="entry name" value="EDRF1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056583">
        <property type="entry name" value="EDRF1_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15000">
        <property type="entry name" value="ERYTHROID DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15000:SF1">
        <property type="entry name" value="ERYTHROID DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23788">
        <property type="entry name" value="EDRF1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23723">
        <property type="entry name" value="TPR_EDRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EDRF1 N-terminal" evidence="3">
        <location>
            <begin position="269"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="EDRF1 TPR repeats region" evidence="2">
        <location>
            <begin position="867"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="548"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1179"/>
            <end position="1190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1294" mass="146130" checksum="A20F8A73FE6D0BE3" modified="2019-04-10" version="1">MDTKEDGEADTQSINNPASHSNLTPTVLNSLVISPSKSVTRPTQALSPIRKPPLGLSHGSYLENSDRGRAYSRPGSFDSKINGNLNENQDGHIRSVAVVKSSEVEFPVQFHELQSNTDLKMPPSNWLQDHSSIRLPNPTHKHADFSSFLMAHQFLDCIGEVDVISDAENIKKLLKIPYNPKAHVSMMIHRVGKTLLIDEFDIYKYLLRQSEKEWQWLRKFFFEHVLQSLAHKENVLVRPNKSRNVVQSRSLLSKFLYHSINEEENRPASPPSQPETESPVSVRREQRRQSDVLPSVLRNEVMPEPTIEDQLPQASGQTFTRNVVWNFEDLHMLIGTDLPIFGGGTHPCVSLRLRDMNKPINILTGIDYWLDNLMCNVPEVVMCYHLDGIVQKYELIKTEDLPHMSDSQFSPTLVRDVAQNILSFLNSKATKEGHTYWLFKGKDDDIVKLYDLTSLCMEGCISVDGLEEETQNEDASNPFTVPVAMLFYRVAKNMRTSEDAQNKIATIRALLRNSLSLLNKNEYPKIVSSAHYMLSDLYVPQDIDPDSPVLSDCSDEDSEWSSTVSSDNEDQSDDECNAEDHSVTLSNRSSSIKVSSLCFPHANKTQSQHYKAPPLLGTLEERCHCALNHVIEALQCLHISSTSEREHHSSPRGQEPMCSRSHQEEEPKMARPFEPIPMPYSPLNAEKQDEKTALVVAKDKTTDHRLTVSLFSQQYAVASWWDKLHVLVLRKASLVYLVMARSCFNSQRYGLALRYVKFSLHAWDGMARKLGVKECDVPVPCQALTLAGDTYYMLSKAWDEVASHIEDYNNVISAHQDMLSLLSNILPAQECNWTIKLACDVEEALRLSSMCFEKALSSADPQTAVHLSRRLGNICNELGVMYMNQASKLCEENDIGFQAAEELWQRSAEVLNRGITNFTRVGDVTNIALLHSNTGRLLRLCAFYCVPKEGVREFSKQERHYYDQAIKEYQKALEVLKSRKKCPDIWDLVVWEFSTTLYTIASLLQDHPPLELKPGEEHSREVMDLLTKALKHCDVKTPGARQPLYQYRAAVIYMRLAGIYHNAVRHSQGDKKTMRHLAELNYSKAAALFMQLENPIDILKVQLDQAVLIEDQMSGTANTPITMKLHFSILQLLMESISALKIITQTVAKPKTNLLGAEGNSGEPAASCSANPREKFHTGSPSRNKAGDNNNGEEKEIQPQTEAVIYDDEESQEKILALLKVFEKKLQNSLMSLIKLYAQSKGSKKSSSYSGNEVTLLKQMYSLSLNTQSLPLGSHLLTAVTAISPLFNQIRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SU19</accession>
    <name>A0A3R7SU19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Caspase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006398</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001811">
        <property type="protein sequence ID" value="ROT75112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SU19"/>
    <dbReference type="STRING" id="6689.A0A3R7SU19"/>
    <dbReference type="OrthoDB" id="6097640at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p20" evidence="6">
        <location>
            <begin position="617"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="842" mass="93513" checksum="205CE3FD99C6FEAD" modified="2019-04-10" version="1">MPMPQKSLVGKPKSPRKSKFSQVNVMKVKKTKTPFKHCIYTRSLTNRLAKRIANHTPLHVFKLKGQLFKAVEDGDVVKVQELIQDTGAAVRKNKSRCTLLHTAASHNQADVVMFLLKLISPNITNEEGQTPAHVAAEKGHTQVLKLLMSDSDFDADKRDNCHNTLGGHLFKAVLEGNKKEAERLLAVGADPDSHGGKLVNGVLARELGVTTAGLLASALNMEWAVTMFAKNARNDKTGETGLLTSAVSNSVQLKVPSRQFRVRHATAIQGGADVYKMDKEARGFVRILNFSCFKDRSDLNLQQLDYDACIMSDVFDKMGYMCKTHSSLTAQQTKEVMKNIRDEYTVKNKTFRRDDVSPSQPILLNKLFPENMADKTPPYIPEDYLPLEEETALRSQGQLFKAVEDGDVVKVQELIQDTGAAVRKNKTRCTLLHAAASHNQADVVMFLLKLISPNITNEEGQTPAHVAAEKGHTQVLKLLMCDSDFDADKRDNRHNTVKSLLGGHLFKAVLEGNKKEAERLLAVGADPDSHGGKLVNGVLARELGVTTAGLLASALNMEWAVTMFAKNARNDKTGETGLLTSAVSNSVQLKVPTRKFRVRYETAIEGGADVYKMDKEARGFVRIFNFSCFKDRSDLNFQELDCDASIMSDVFDKMGYMCETHSSLTAQQTKDVMKNIRDGDELTDVGCAIFVIYGYSVNGRSVLTSDMKCVDIDYMLNAFKDSECPQLKNKPKFFIFNLYNTSEVPTNSGNQTPKVVRLTDPLNDMVCIYSNSIGVNCVPDGEGTSFNWCLCRTLAHRAAVQEFGALYRAFLKEYSNSSPSSSPELRYFGFTKKFFFNPMQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUV0</accession>
    <name>A0A3R7SUV0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Repressor of RNA polymerase III transcription MAF1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SUV0"/>
    <dbReference type="STRING" id="6689.A0A3R7SUV0"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="103" mass="11865" checksum="6911665EE7229A8B" modified="2019-04-10" version="1">MRAVERQMMAVARMEFTPVASSLWAALDDAICLKDCEIYSYNPDLTSDPYSEDGCLWSFNYFFYNSRLKRIVFFTCRSVSQYCGSPHDSGLIGDSSMDFEDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVS3</accession>
    <name>A0A3R7SVS3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001501">
        <property type="protein sequence ID" value="ROT77633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVS3"/>
    <dbReference type="OrthoDB" id="6347625at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="42269" checksum="AE113BB49410437D" modified="2019-04-10" version="1">MAVWLDTFKDTEEIIEVVTNQTVGRLQWQEARDTCGIVLDDEELSDAVDGVRQLKMAIFDLIVKSESLSEHIRVFANLIISINQQASVVEDDMAAVASSQQSLAEANELLSDAYLTEENYLDYMVGQNVALAKLMVQLYLKNRVDLMAAFNVLGEYCDAYFYTFMKECPIHASYWDDYDTMVYKLRQLDVLALDAVGSLDPPPQPFAMTFNVFDEGGCEDPADPRCPVTQLAYTGIAHLALSDWWGPELGYTDRVRIDRIRLYLEGLDLSQVTLSVTRPMAFNDTWHGVTHHFTGHVTNCLIIYEDLSFTGHQDADYITDCSTDHHYDQYYYRSTPYGVYKVVWSDFVPGNNYTELMALQVHVEGSWIPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SA12</accession>
    <name>A0A423SA12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021214</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004405">
        <property type="protein sequence ID" value="ROT61050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SA12"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="664"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1132" mass="120275" checksum="6AE0AD57D1595BB3" modified="2019-05-08" version="1">MEKEEEQKEEEKCKSEEVDSEERSVDLRRNVPFLSVASLLGPPPISRVALLFSGSSPHPLGASFRVPPPILRIASLQWSSRHPPPWPSFMGLLLIPLSGSSPHPPQSFLHVAFPHFLRSASLLQASLPFSPTLSFPVGSPLISPDALPFYSLRSPPSGLPHPFRLSFSSWAFLPFLLDLPPSIGASLSILPDVLPFFRASPILSTLFLFRGPSPIPPGVPHSVASPPFLRLALLSGPSLLSLFRTPPFRCLPILPGTASFLGSSSPFLLTLSFMGSLPSFFPNALLFRAFSPILRTPPFSGPSPIPPVSCLLQGLSPIFSDVLLQCVSFPHPPDHLSFFMCLSSILLRSPPSGLSPSFLGASSPNPPDTSLLGPSPHPSDHSLLSWCLSPSSGIAPSVPPPLSIPTPSLLGWLSPLLSSGPPLLSWPSLHSSVIASFRRFPRILLIHLPFRTSSSIPPTPPSRASPILRTYLSSGPPLLSSDTFLSGPPPILLAPSFMCLLPYPPDVLSSGPSPISPDTSFRCLPHPLGASFRALPHSSWRLPFRGLLPDSFRRLLFRGLPHPPFAFLFRASPPILRVASLQASPILRRFPFQGLPSILEASFLRLSPIFLRTPSFRALSPILRTFLLRGLALSSGASFQGLSPIPSFPASFLQALPHPPYASLQGLLPSSPTPPSGLPHPFHRPLSLPSSPTPPSGLPSVSPLRPPSWGLPRSPGFLLPSSDVLFLQGLPHPPTPPSGPPPFPLTPLLQAPSPLSLLAASFRVPPPILRRPPSGCPPHPPTPPSGAFLPSLPVRLPSGSSSHPPAPPSGPRPFLRRLSFQGLPHLPDTSFRASPISDASFQASPISPTPPLVAPPILRRSLQVPPIPPTLSPSVASPSSGRLPHLSSAPPSGPFLLIGLPVRLLSGSPPILPACLLQGSLPILRRPLFRAFPYSFRRLLQWASFPFLHRLLQGLPHPPAPPSGLPPVLRRLLSGPLPRPLGASPISGGLPFSGPSLPILSASSFRASPHPPAPPSGPPPSSSGASFRALPPISPDASFRASPSFRAPSQGLPILRHPQGSPHPFRRILQGSPLIPPTPLLQASSHPPAPSFRPPPSSGALLQGLPLLRRLLQGLPHPPAPPPSSGASLPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAB4</accession>
    <name>A0A423SAB4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021106</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004331">
        <property type="protein sequence ID" value="ROT61150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAB4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="41326" checksum="D7EFFA7F330E373A" modified="2019-05-08" version="1">MSLFVLPFFFFSSSFSFSSSSAPPHLSFLLLLFLFLLLLLFLFLILHLFILPFLPPSPPLLLFLLLLLLLPPPPSSPLLLQVLAPLPPHPLSPIIPPPPPRPLPPHLPLLLLPLPPPPSPSPPPPPPLLLFLLVPPLSPTPLLLLLLLLLLLLFSLFLLVPPPFLYSPSPPPPPPPPSSSSSSSSSSSSSSSSSSPPPPAVRQPRAQLPTRQLTQFARGQATVFDFLVPPLPPPPFSSFFSSTFSFFFLPALLLRFIFSFFFFLVFVFLSFFFSSSSSFSFLLLFLVFVFFFILFFLLPVFVFFFFSISSSFSSFFSSSSFSSFSLSYPPFFVVLFPPFLRIFFFLSSSILVLIFLLIFSSGFLFASSSCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBZ4</accession>
    <name>A0A423SBZ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004011">
        <property type="protein sequence ID" value="ROT61731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBZ4"/>
    <dbReference type="STRING" id="6689.A0A423SBZ4"/>
    <dbReference type="OrthoDB" id="429520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.190:FF:000003">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.190">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006789">
        <property type="entry name" value="ARPC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036743">
        <property type="entry name" value="ARPC5_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12644">
        <property type="entry name" value="ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04699">
        <property type="entry name" value="P16-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039096">
        <property type="entry name" value="p16-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69103">
        <property type="entry name" value="Arp2/3 complex 16 kDa subunit ARPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="153" mass="17035" checksum="9794E4DAEE75EEEE" modified="2019-05-08" version="1">MAKNTLSSEFRNLDVDQYNEDNYKEDDGEPQSPPIGIDEATIVSHINSGNHADALKLLLTNAPVASKGKNEQVKDMALNLVLKVLLSVNKSQMDQIIGVLDQTHLDVLMKYIYRGFERPSEGSSAILLIWHEKVYNVGGVGCIVRVLTDRKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFU8</accession>
    <name>A0A423SFU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative cytoplasmic dynein 2 heavy chain 1-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019028</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003494">
        <property type="protein sequence ID" value="ROT63097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFU8"/>
    <dbReference type="STRING" id="6689.A0A423SFU8"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000006">
        <property type="entry name" value="cytoplasmic dynein 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000710">
        <property type="entry name" value="Cytoplasmic dynein 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000003">
        <property type="entry name" value="Dynein cytoplasmic 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000006">
        <property type="entry name" value="Dynein cytoplasmic 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000598">
        <property type="entry name" value="Dynein cytoplasmic 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF22">
        <property type="entry name" value="DYNEIN CYTOPLASMIC 2 HEAVY CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="2">
        <location>
            <begin position="2"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="1">
        <location>
            <begin position="442"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="3">
        <location>
            <begin position="584"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="4">
        <location>
            <begin position="758"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT63097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1029" mass="116248" checksum="BB71CF21E28F7190" modified="2019-05-08" version="1">MTPFLIDPSSRATTWLSEHLKDRTVEITTQQDPKFATNLELAVRFGKTLIIQEVDKVDPILFPLLRGDLISQGPRFVIELGDKTLDFNENFRLFLATRIPNPELPPNVMSILTTVNFTTTRAGLTGQLLAATLQVEKPELEVRRTELLRQEEDLKVQLVNLEDHLLTTLAESQGNILENKVLIASLEKSKSSAATIETSLKESMSLQESLENERKAYLTLAQSAANLYFVISDLSKLNNMYQFSLNSFHALFHKALQTPQDGSATENRIKVLQRALIDLVYSYISRSLFKADRLMFGLHLVHGMYPEQFQKNEWQAFTGQLVTDVKADASELKEALPNWIDEERAFAVALLRQTFPALYDMLNLDDMSMWSGFSNSNHCELDFPVQLNQKLSPFQQLLVIQAIRPDRLQSSMVNFVTRALGMKELSPPALNLRRLLSETVATEPILIIISAGADPSQELLDLVKSTVGSNAYHEVAMGQGQSEIAVRLLHECAKAGHWLCLKNLHLVTAWLPTLEKELNNLHPHDNFRLWLTAEPHLKFTPILLQTSLKVTYEAPAGLKKNLQRTYDSWNPELIARDNNVNRAQTLFVLAWFHAIVQERRTYIPQGWSKFYEFSYADLKAGVDIIDRLYKQAGTGDIKWNFIYGLFENAIYGGRIDNIWDIRVLNAYLRIFFNNDVVGGRKPSADQLVKSLALPTTVNYQDYTSLIRNLSDDDDPSYFGLPANIERSWQRIVSSQVISQLKVLMRSPELAGRFDREKWHTQLSPVLNLWKKLNQGGNLIQAKVATPSSTAESPVKSFIQLEYYSVISIVQTVHRSLAQLSKVIRGTLLLTSDVQKLADSLLSQETPSSWLSLWEGPEDPLEYLRSLVRRANGIGKWVAKSDQGNLLKEPLDLSDLLHSATFLNALRQQTAREYSTSMDSLVFVTSWSRGGIPDAKLTMKWSGLQMEGATFDGSRLQHNAHDSTSISVAPLCAVAWVPKEVQNRLYHDELLSVPVYSSSNREQVVASVTIPCPSPHYEWHQAGLALFLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGW9</accession>
    <name>A0A423SGW9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">26S proteasome regulatory subunit RPN9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">26S proteasome regulatory subunit S11</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">26S proteasome regulatory subunit p40.5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_018719</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003444">
        <property type="protein sequence ID" value="ROT63409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGW9"/>
    <dbReference type="STRING" id="6689.A0A423SGW9"/>
    <dbReference type="OrthoDB" id="1093at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="123"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="37432" checksum="AEBA5EF90F3B13FE" modified="2019-05-08" version="1">MKEGTELIQLYNNLIGELENKINPLSLAQMAGEVVAQYADANEGIKFMEKIAPKVVDHQEAKVLCNVLIAQMYLTKLEDQTRTKKILDDTEKMLDEIEGVTPVHGKFYLLASDLYCRSGAHADYYRAALRYLGCTEVDDMDAETKSKQAFYLGLAALLGDGIYNFGELLAHPILESLKSSQSVWLLDLLLAFNQGNISKFETMKPQWSTQPDLLNKENQLREKIRLLCLMEMTFQRKAWDRQLTFTEIAQETGLPENQVEVMVMRALSLGLVKGTIDQVDNKVNITWVQPRVLDKKQLETMMDRLTDWCKDVNGMQNLLQDQASTILTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-09-13" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHR9</accession>
    <name>A0A423SHR9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_018300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003376">
        <property type="protein sequence ID" value="ROT63800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHR9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT63800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="43003" checksum="F99CCC533F4CB384" modified="2019-05-08" version="1">MSATHRDYQRAAPNPLTALTSFLSSDAADNRTPTEILHHFQRLLTRIGATLPPDVMRSLFLKRLPDYPANPGWCQMPHWSKLALQADAMLVARATNIVNSNSVCCNHHLRRDVGSPCSPCRHTNPRRAEDIHTGNVLTPRPRFRTPSPPHIEQNIRRSTTPIHTASSLPRSFTRRAKSGRNRGNWARLSFADLGERLLYVRDASSSIRFLIDTGTEVSLLPASHRDKRFLLPHSGSCQHITHQQLWRAFKDPLRGSRARPTIQVDLPRRRRPTHHRRRLLGTLRSDGRSAIYGPNPPIPGPARTLLRVLVTVPNYNCASRSWRPSRTSWREFRPLTKRSSELPSHGTRSSHIVTHVPLPTLAAVHVRPTDVVVPRRSSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIG0</accession>
    <name>A0A423SIG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003348">
        <property type="protein sequence ID" value="ROT63981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIG0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="535" mass="57022" checksum="EED505F7C092BDC5" modified="2019-05-08" version="1">MRPCPSKHGRAACFAPPTVPLGVRARGRQRARGTGRLVWSASGSASPAFRHVNPTLGPNGWQAGMAGAGARGRTGHPRQQRRKREQTLHVFRERPDAGPASLQRPSRRTAGAAVEHTRSRPYCVPGGNVTTLEGRWQPSFEEGTGPPQCAFDTSMESRENCDSHQNFASCRGLPTSQVIPVKSLCWVSHLCVSRLPLNEASKGRRTCALRKRVAHGAKHPAHKTGLGAVAHLVGPGDPGGADKDFWVRPPPSPGGGEKRPGSRAESPPWMGRNQASQPASATGRWRNNDGQPGCTVARPPKPRRQTGEWAGGPAPTAAAAAAAAGSRRGSPPAARSRGSPPVVVGAGPQPTRPGRGRSAPGATEGSPSDGPGSQDPPKACPAFGDGSRKGRGRQNNIRLQTPPEERHTQWGPGRNSRCKARLRRQASKQAQTGAGRRRASQARGKGEGRYSRWPSLLFNLPHPWAPQEEGRGIAGGFFLSRRKGVHTRDLTPRYRRNVAEGRRTAGGSAVARGRPQKGGGTRKPFRTSREGRSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJX7</accession>
    <name>A0A423SJX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003237">
        <property type="protein sequence ID" value="ROT64545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJX7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="44675" checksum="0B172608CEE2966F" modified="2019-05-08" version="1">MTSPKSPCPGVRALESVPWSPCPGVRALESVPWSPCPGVRALESVPWSPCPGVRALESVPWSPSPGAWSPCPGVRALESEPWSPGVVPWSPSPGVRALDGVRALEPGVRAWSPCLESVPGVPCPGVRVESVPWSPCPGVRALCPPCPPVPWSPSPGACLEFRVSWMESALSPCPGVRAWSAPWSPLESVLSLESVRPWSPCPGVRPRVLESVPGSVPWSAPWSPCPGGPCPGVRALESPGVRPVPWSPLEALVPWALEFRALECPWPWSPEPGSPCPGVGVACLESVPGVRALESVEPWVRRPSVPWSPCPGVPLESALESGPCALESVPWSPPWSPCPGVRALESVPWSPCPGVRALESEPGVRAWSPCPGVRPWSPCGVRALESVPWSPCLSPCPESEPWSPSPSPSWSPCPGVRALESVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SP34</accession>
    <name>A0A423SP34_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003005">
        <property type="protein sequence ID" value="ROT65990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SP34"/>
    <dbReference type="OrthoDB" id="2142683at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="16539" checksum="C54AED9C7270D01C" modified="2019-05-08" version="1">MPGCTSPFKSYGTKGCLQVVLGKRPLTWHSARSECQAKGGDLAVLDEAEKFRALSAGIDEEHPDMTKGGFTFWVGAERVESSCAGRTASLWSRMRSCGWPGSLLPAAVPVPPSWYLLEALRDVATSPTSAQIPLLLLSSARSSKFEGSSGCECGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPX0</accession>
    <name>A0A423SPX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002965">
        <property type="protein sequence ID" value="ROT66257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPX0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="42779" checksum="3850612EC09F5391" modified="2019-05-08" version="1">MAARHVIFSQCNDLTTQGESLHSFPPSSRSCGLEVTKTRNSARCADSSGLYKVGEPRFDSCTRSGARPPLPRSRLLQSRSQARQGEQPRRFTPFKLAFEAQSSLSQTPSLAPSQGRPSEKLLVWHAPPREISHLDPTASFPRLACVQVCSSIDRMFRARKLLQQSNFYTSSSFCGTLLPHSSPHRWMPKTAIRIVLFFIGLVFSLRRCLPPSRPSRPSTRTTGLPQDRRRRPQEGQALREVFADYDRPDDRAAEPSQGAPPHAAAVRPSPHAVPSPHDARLVSFFVFPHDARPLSFLPRSVLLRLPLMCPSVFFVFPHDAQPLSSSSSLMMLPLSSRLPLMMLLCPSSSSMMLASVLLSSSPHDAASVLLRLPLMMLASVLLRLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQT3</accession>
    <name>A0A423SQT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_015381</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQT3"/>
    <dbReference type="OrthoDB" id="9996086at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="68"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT66582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="42627" checksum="D4333ADF8F72AC85" modified="2019-05-08" version="1">MSSWNNPNPVTQLESTNPYGNYTVVDTAPKEILHMVHEHWYQFPPMNPLWYGLVGFWMVIMGCLSIAGNFVVIWVFMNTKSLRSPANLLVVNLAFSDFLMMLTMFPPMVVSCYWQTWTLGALFCEIYAFLGSLFGCASIWTMVFITADRYNVIVKGVSAEPLTSGGAMLRIAGTWFFSFAWCLPPFFGWNRYVPEGNMTACGTDYLTESEFSKSYLYVYSVWVYIFPLFYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFMAWTPYFVINWGGMFNKPMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACNTDGRDGGGSDAGSTATTAENNEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVJ6</accession>
    <name>A0A423SVJ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative tripartite motif-containing protein 2-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_013693</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002709">
        <property type="protein sequence ID" value="ROT68188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVJ6"/>
    <dbReference type="STRING" id="6689.A0A423SVJ6"/>
    <dbReference type="OrthoDB" id="342730at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF296">
        <property type="entry name" value="MEIOTIC P26, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="7">
        <location>
            <begin position="69"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT68188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="146" mass="15733" checksum="3B2318E9ABDB4663" modified="2019-05-08" version="1">MSLLKVLPCLHTFCERCLISYTPPESLTLTCPVCRQQSILPKDGVPGLQSNTWVRGVMEAMDGAATGPCSICHQANPTARCHQCQVAFCAGCAQAHVQDSGSESHSVVSLADSESGVPDTNGFHDDNTTLYCPSHQGRERRVWKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXA1</accession>
    <name>A0A423SXA1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Transient receptor potential cation channel subfamily A member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_013065</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002635">
        <property type="protein sequence ID" value="ROT68773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXA1"/>
    <dbReference type="OrthoDB" id="1661883at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF1">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="506"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="540"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="68"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="360"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT68773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="690" mass="77942" checksum="0CB94C382AD25C53" modified="2019-05-08" version="1">MFPFVDCVILTFRPGRRGHLCREPLFGGAARGAQGRRRPADGGWAAGRHTRVVQLLLSKGALLHRDHHGRTPLHLAALGGHRDTISAILTIHSHTLDQTDKEGNTALHVAVRANKPETVSQLMSLNCKFLENLASCKPIDIAIQYKLSESALALVTHDRGPTEVLGTSSKIHGCICMALIRTLPKVFESVLFQAIVKADVKEQAKDFYIKYNFYPLQLTPEQLDAEKIKQKNPNFRPEPLYACNSSVSIGTNPPQPKLSPPTPSTPHSPPPTGDGGVRRVELLMHPLTQKFLEMKWQAYGKYIHLSNLFVYLVFLALVTIFAVGVLGQQSFVMSNVTRVPVDNVSDITTTGEFQLHIEDTPGWMFCMAIGITVFAVLSMMKEAFQIYYHRLKYLAEAINFVEWTMYLASICMVMPVFLGTNWHNQQYNSAALAVFCSWFILLIYFQRFDRIGIYIVMFLEILNTLINVLLVFSVLIVAFGLAFYILMSHGGQLSFSNVPMSMLHTFSMMLGEVDFLTIYVYPFYQESTRGDILLFPRTTFALLVIFMILMPILLMNLLIGLAVGDIESVEMHTELENKLPEMIIRRVNKSELVIYPNCRKGTHLMNKILSAFNFACPFSDKKGTELESADSAGDDYLWEELEGQRRRLRDISAVLDTQTKLLRLIMQPFPNRKFAPSSATSRRAILYRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0X8</accession>
    <name>A0A423T0X8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CEP76 C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002497">
        <property type="protein sequence ID" value="ROT69938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0X8"/>
    <dbReference type="OrthoDB" id="5527234at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028926">
        <property type="entry name" value="CEP76-C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15627">
        <property type="entry name" value="CEP76-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CEP76 C2" evidence="2">
        <location>
            <begin position="90"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="139" mass="15147" checksum="A92F6DA0080AB200" modified="2019-05-08" version="1">MEGGEGSISPENESPSCQVDLKSSIDNLIQEVATQEAIGSVDPNALVTQLLNSASVQSMLQRVSVGSKGHKNRQGLTSNLPPQVQEKMVPGHRYLYVHVGGGRAFVDHLEEEKNKTSSQSTLLIILQFMSQRQGQEFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3A6</accession>
    <name>A0A423T3A6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UmuC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_010723</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002364">
        <property type="protein sequence ID" value="ROT70976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3A6"/>
    <dbReference type="STRING" id="6689.A0A423T3A6"/>
    <dbReference type="OrthoDB" id="5723at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009314">
        <property type="term" value="P:response to radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000003">
        <property type="entry name" value="DNA polymerase eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21704">
        <property type="entry name" value="POLH-Rev1_HhH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="9">
        <location>
            <begin position="6"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT70976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="299" mass="33092" checksum="7C54BA167D13DDF4" modified="2019-05-08" version="1">MTDRVVVLLDMDCFYVQVEERDNPHIKGVPAAVVQYNSWKGGGIIAVNYEARAFGVKRGMRGDEARGKCPDLQLVQVPVNRGKADLTKYRDAGKEVIKVLCEFSDCVERASIDEAYIELTQTVEDRIKKKNGTHIATDMLKSSWVVGYDKTKDGDQQGVREKGVHEWLNSVFENGEDAALPLDSNHPQWDNVRLAYAALICEDMRAAVLAQTGFKCSAGITHNKMLSKLACGLHKPNQQTVLPQDEVSQLWDGLPVGKVRHLGGKLGDSLTEEMGCNTMGDLAKLSLQQLIGRYDNKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8A5</accession>
    <name>A0A423T8A5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endonuclease G, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008958</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002125">
        <property type="protein sequence ID" value="ROT72652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8A5"/>
    <dbReference type="STRING" id="6689.A0A423T8A5"/>
    <dbReference type="OrthoDB" id="5418055at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="entry name" value="Extracellular Endonuclease, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="Endo_G_ENPP1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="ENPP1-3/EXOG-like_nuc-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966:SF5">
        <property type="entry name" value="ENDONUCLEASE G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="ENDONUCLEASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="ENPP1-3/EXOG-like endonuclease/phosphodiesterase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640255-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15602" checksum="39585168A600F6FD" modified="2019-05-08" version="1">MSPQVGRGFNRDKWNDVEQYCRQLTKSYANVYVCTGPLFLPRREEDGKLYVKYQVIGQNHVSVPTHFYKVVVCESSTGELDLESFLLPNVEIDDSVPIASFHVPLETIERASGLLIFDKLSQKKFKKINGQKVGWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAZ1</accession>
    <name>A0A423TAZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative stAR-related lipid transfer protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_007959</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002015">
        <property type="protein sequence ID" value="ROT73598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAZ1"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="5">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="375"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT73598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="43467" checksum="E989AB9EC0399BFB" modified="2019-05-08" version="1">MPLNLFQESPGLAPRICQGLLTRLQQRYAPDDLCAQDFSLTLSLVEIYNERVRDLLTGNDQGRHLRVREHPHTGPYVDGVTRHPITDTSEAWALLERGRASRSVAPTASHAHSSRSHALLTLDVTQPAAHTRSALTLVDLAGSERASEEVDKTRLTEGASINRSLVTLGNVISALAERGANLGSTVAMSPLGSNLSLYSATSRPSYAQSHTTIPDGYPAEGQRKASKLPFIPYRDSVLTWLLKDTLGGNAKTLMIATMSPSSTSFAETVATLRYATRARCIVNMPVVNLDSGTATIRSLKKEVAALRRLLCDANNIRCDPTETTLPSSPSTKPLAVITRHARSLGRKWGAHGTFGIEQRITRSLILKIASTNRGPAYRDRLSGNQKSPDGSGGPKSETEASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCV7</accession>
    <name>A0A423TCV7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007228</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001915">
        <property type="protein sequence ID" value="ROT74295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCV7"/>
    <dbReference type="STRING" id="6689.A0A423TCV7"/>
    <dbReference type="OrthoDB" id="73348at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045230">
        <property type="entry name" value="MBS1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213">
        <property type="entry name" value="GEO09665P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21213:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN 706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="77" mass="8511" checksum="FE6DE9374A9C256C" modified="2019-05-08" version="1">MARGHQKAQSQAKNLAKQAAIKSKQGHNANAQKKAAAKALTYQCPVCRSMMPDPKTFKQHFENKHPGAPMPEELKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDS2</accession>
    <name>A0A423TDS2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 2 profile 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006937</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001878">
        <property type="protein sequence ID" value="ROT74551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDS2"/>
    <dbReference type="OrthoDB" id="6506272at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15039">
        <property type="entry name" value="7tmB3_Methuselah-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053231">
        <property type="entry name" value="GPCR_LN-TM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902:SF5">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="6">
        <location>
            <begin position="41"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="314" mass="35159" checksum="E9BF9F82D7AA36C1" modified="2019-05-08" version="1">MVNDTVVIKVSNRTYYPGEYEVVEEGVLVCSFASDKYSAAMGWVTLAGLSASSLCLVLHLVPSPSCLTQDLHGRNIFLSLLGAYVSYILSVFAETSTTECYVFAVLIYYLFLTSFSWMNVLGFDVFYTFRRSRVRSGEQWKRFLVYSAYGWVLPACAVAAVVAVDQTRPPGFPPEFLPSLGQHLCWFGRRKALLAFFGAPLIASIVMNVALFVATTVSIAKTMQSEVRRTSPSEPKKEFLLYLRLAVLMGITWITSVVASYLELEVLWYVFILLNTLQGVFIFLAFTCRVKVWEAIAQPCQASSSVSCCRRQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THI1</accession>
    <name>A0A423THI1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001726">
        <property type="protein sequence ID" value="ROT75827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THI1"/>
    <dbReference type="OrthoDB" id="6354858at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008028">
        <property type="term" value="F:monocarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF306">
        <property type="entry name" value="RE01051P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="572" mass="62511" checksum="F4F08EE5EB24FC34" modified="2019-05-08" version="1">MDTGTSRRMPGLLAAVMGAFTVMVGPRACVIIGSLTVTAGLLAAVPAVSIVHIAFTLGALVGVGLCMSETPGFLAVTDYFQDKRALANGFRAAGNPLGGVLFSPLVVALHQYFGLQGALILMAGIMLHMAILGALMRPFQIHQNLVQAEFWKDQARQNTPGLRVSSSQQIKPSDQKRKKKKPLNFRMLKNPSYLIYLLMVMCVNIAMPNALLYTPTYGKSIGLSAYENSVIASYTSACDFVMRLLCGWTSSLKLYEAHHGLIAGLLVGGIGCLLTPLCNNMWQLLGAATSLSFCMAFFWTLINTLLADEFGGDAMASTWGFFRMTQGICSFLYPSLIVFLWRHHRFLVFLSFLTFSIPFFFISLFSLSFSLSFSSLLNNLLSLPSILYLLSLPTLLQHPLSQPSLLFHLLPSHHFIILFPSHLFFIILFPSPLFIIPFPSPLFFIILFPNPLFFIIIFPSHPSPHQPLSLPFHLHHPPPPLSSSLSFPPPSSSPSSPLLRLIYYQPSLSLSFSPGLVLDATGGLTIPYLMMGSALVLGAGVFSLRPLIARISGPKKELNPQSSSSLRGEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THN3</accession>
    <name>A0A423THN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001706">
        <property type="protein sequence ID" value="ROT75963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THN3"/>
    <dbReference type="OrthoDB" id="6368620at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="318" mass="34323" checksum="54B7F78C6BB2D93C" modified="2019-05-08" version="1">MPVVRTGAVTNGYIVRQSVSRSVDGSETDSGCDTKMADDFLFSHYGLEVLIHLSTFLITASTVSTKVYLRSALKEESILTNKNPLLLQIMVYLTIGIMSDLMSPTVALLSTHLTALGVCLLNCLNLSHILMSYLPFLNSGYLGSQVIAASYRQDFGLESMLARVGLVYGLASSVCPQIIVISTEYLGATLNYMVVSLASLLSISAGCRLRACIYQRPSSRTDIGWLCFLGFLLMKVFLTIPLAIMLPLFQGMIQDGSFIEGVSLSMIVTVGLLCIQAVVTPVLLFFTSPATVTIIVAAVLTLIYPALVCGSLIIMEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIM2</accession>
    <name>A0A423TIM2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001675">
        <property type="protein sequence ID" value="ROT76298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIM2"/>
    <dbReference type="OrthoDB" id="6340179at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844:SF1">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="301"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1026" mass="116887" checksum="8219EA47493CB4FC" modified="2019-05-08" version="1" fragment="single">LRNRVYTSTDVLEMSNSKLHPYHFKDQSLMTFRLYEMIMTKGGSVLRWVLSWGTPRRQPKQFFDEYLVEAKGLSRGLIRRVFNQSQREKMKRELAWDMFDVTLLYQCIQFGCDGLALPRDRRWADSGDSLERYVTAVKNFRNDLLHEEYKIDAATFVTKTEELRELLTKTLKKAGEVFKIDAGLVTSIIRKLDEDINNIRDKPLEASSGHMYISDSLRHCVCTQGKLDMKKRYKQLSYFGPASSLLGDRAVVRVDKIFTQMKMVREESEEVNPDEGDIDIEYNDMLVFLESRQSQSSKTNTAVLVEGQAGVGKTTLTRKMVSDWASETTTMKHLVDYDLLILCECRDKSIVSLTHLLESLMANACRKVQREDLIKCIEDKKLLCIIDGLDEINPSSEQVLRQILKMGETNDITLICTTRPNKVHSFKYYLPENFAVVKVKITGIAESRREDFVRNYSQALSFEAKTEDISGLLHFLKRTESRFQDHWRLPFNLVLLTILWFLDTDAVNSLTTATELFMTTHKVNQRKLQKRLFEHEKTRSLEPHELKDKTNKFLRRLYKEALINHYGDDTVLSEASMLRLQDTCDFLQLPSAEVLGTFLIQSTSLTDETKTRYSFPHKSLQDFYSALYITDTLMADEIVLDIPRIISTFENALQSIGAPTCLSQYIDTEKIAKHGASAPSRSIECVLKEGAEEAAKYFAKREENKVAKWNLKDYQNVLCHCASLLHGLGATVTESRASEIVKLLKASGVSDRDQWLDLLTEIKCDATVSKYIAYAMDLTDTVKITDSSVEAYASVLNHASPSRVDICISNDPQQVPGLTKLLSTLSLQTCQVRLDIQNDFQNPKPGGSVLEEALQQLFQSCRVTHFSGQLGREAAEKLPKSLEVLRISIPNDSHYRELSPVLSTLRYRLPRLGILWLHLMASIDPSILQQLPQIQSLHVTLSGVDETTVGWACKAACLLQPVGGFWYRSLMFPGIAKSVYTCEQLLLGLASKGVRVGVRIEVSPRLTPSDRMYLHDLTRPRYTISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKC1</accession>
    <name>A0A423TKC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">39S ribosomal protein L49, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001593">
        <property type="protein sequence ID" value="ROT76916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKC1"/>
    <dbReference type="STRING" id="6689.A0A423TKC1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000009">
        <property type="entry name" value="39S ribosomal protein L49, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="21448" checksum="CD09418C663766A3" modified="2019-05-08" version="1">MSTSPITALFRPINRMNRSLRLARIGNYGRRTLTSTSTVQGISKFPRLQHTIPESYNEVEVSTAEWSFVERLIPPKAIPKPKANPGEVTPSGWVAPSAVPGDYPYFVPRSASHMLPVYVKHEPIMSRFTTSVKKVEGDAFALGEELRQYLSEKFAPKHINLRVHEPHRMIQIKGEYLLEVKEFLISKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLX9</accession>
    <name>A0A423TLX9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_003874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001519">
        <property type="protein sequence ID" value="ROT77466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLX9"/>
    <dbReference type="STRING" id="6689.A0A423TLX9"/>
    <dbReference type="OrthoDB" id="407959at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_uL14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006344">
        <property type="entry name" value="PRK08571.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="280" mass="30087" checksum="3788DF63A39908B7" modified="2019-05-08" version="1">MRTRQFFITPPQCRREFPLWRVCFPGPFAFSHIHRAPHSHCHAANKAFRPVNSQPLPRPPQNSGKVEPKSLVELVFPSPGADPSAAGNGARFMSFPPTPRRPHAPLSDRSSCALGAVTTVQLARCRADGPDSDPSRFLGKAILFGRGGTAGGKFRISVGLPVGAVMNCADNTGAKNLYIISVSGIRGRLNRLPAAAVGDIVAATVKKGKPELRKKVHPAVVVRQRKPYRRKDGVFIYFEDNAGVIVNNKGEMKGSAITGPVAKECADLWPRIASNAGSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQN8</accession>
    <name>A0A423TQN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001336">
        <property type="protein sequence ID" value="ROT78775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TQN8"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF37">
        <property type="entry name" value="FIRE DANCER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="334"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="554"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1044"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1237"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="612"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="754"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="775"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="800"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="838"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="928"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1052"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1081"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1123"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1238"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1316"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1387"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1411"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1443"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1490"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1508"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1550"/>
            <end position="1565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1619"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1637"/>
            <end position="1648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1702" mass="183480" checksum="3E4D77AAF6D7682E" modified="2019-05-08" version="1">MYYPFSLSLSPPGCGNGKYLHINQQVFKVGVDRCFNLTGAARDRDHEFESQDVLVPWHRPEQSSSDDKASSVERDLNSTTTDDDDVLHYHAHNHSDSDSCPSNRCGSRRNGRRRTRSRAIDPAGAASSSQSSSDLSSPNESCYSFVRRALQVASDTSNQKLTSSRRGSASSGRSWFMHGGSFSGFRGSDGRSLNMESGGTAEPRPSFSDDHHQRPSVSNDGSLDSQENLDDVPIELRHLEPEDPALLDIPPSPAPFLPHATAASADPDTKAKSKSLTDLVQASPRSPGNPVCPSGVLSVREKSISREALDMGRAGVSDILGSVLRSKSSSSCLSLSSHEMSNSEGARGCSGGAKGVEGDAASARVTSEKPKVEETKVSEEDSPRVSRKRPTLKKQKASINESDANDIDMPIVIEISKAPKTAEVVNVPVATDDKDHLSIPKGLGIIKQSSLNDEYICIDRFLEKEKLKQSIQKQSSLNEDLIYGNKEERQETMRESLFATQIKRLQNIRESLQQRLRTASLDRFEREKSDSSLKAGIVKLLQSWKSEILVTAGTKPTADEGSAGREGEPSTGPLPEGEDDQQASSSKKHNEIKPKAQSIFQMGRSSDSTDGGGDKSATRGMEKKFLGREPGDRKSSREESSDSSKENSFQSDTSLDSEDSCVSVIFVPKPGQAGIVPGADKERNRSVSSESSEGSDKQHSPKSPKSPKSPKSPKSPKSPGPGGRYFAPSRYLGTKATGKTGPKMGTQVLGGTTRPEQQTRRLSPPSSEGNQDIVVSTANPNTSPTTTTTVSEASADSVPATGSQEAQSIRTVAVVPPRTSFGRGGGSGVEGEGEEGLRGGGGAGAGGGGRGGGGGALARVQRHSGTTPPGTPPPTVSSSSSSYFSHMPVPKVAVPTEMPSAPPSVSSAHPSQDKAGPPPPTALKMPPVVTSTKATTSTVATTSTHSNLQSSSPQQAQTQQTQQQPQQQQQPQQQQQTQQQASKYIPKYEPQVVKRDTSFTQQLSSLLLGENVEIIRKTGRTGTRNVQIVRRTVPRFLTFEVFNPETDDLDSDSSASSSPNSGSSVIERGWPTERDIEELDREIKRREEEERRRAVPSSSGGGATPGERVMPPPPPAEVPKVSLVEDVHRMDTISEDAGEHSGTESNGGRADKKRTSRPVVPAPLVAKPQVIPKPPARTSSKCRSPVEQYRIPMEQYTTGGGSRREYDFGRQRSSSMSAAAACDSDWRFEGYSTKSGTASSALMAAAASSSSSSSSSSPSASSSILDYGREVPLRKSPTSRRKLTICHLDQPPLPLQPTLEQVPEARKSTMRSPDPLQERLGLRTRVSERHPPPKALSPLGSEGTSRGDMKPWAEVAIKPFTETMGMPPSSSWRGRYSPEGSIFKSIPEYDKGAAQKKAQEAKKSSLELPFTSSPYRSSLSPSSSVSSTSPSLPRELGKEDPLTKSPLLSSPTLSTSSGESRSSSQMTMALFGKESRENPFSLEMFKMNRSESSLPLLSPDESQPNHGTFKEPVKPTVLKEPKRTQRLKHDADEPKKDTKHRSSHASCKTSAKEGDKLSSKDESSSKQRKSHTSSLKGKGSDGGWRRGELRSQGSLDSAREKESQASKSTPPLIRSGSLDLEKAERNQREGGLSRDASLSNSQDSLQSDMGGAPTLHRYYHVFREGELDQLIEKYVQNLHIISSYYDHANWCIVAEKVQVWTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TR52</accession>
    <name>A0A423TR52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative serine proteinase stubble isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_002330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TR52"/>
    <dbReference type="OrthoDB" id="414661at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000006">
        <property type="entry name" value="Serine proteinase stubble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="364"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="270"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT78934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="607" mass="65494" checksum="6B04A861B6C5DE26" modified="2019-05-08" version="1">MFLEVLEAKDSTARGYTPLPRRHVLWVCTGALLSAAVFVTGDLPSPLARLQPQGRAIDTHTYYSYNKIAHKACRVGGVEGVCMFVWECIKTDGNHMGMCMDGFMFGSCCSHDEASNSLKPSSGQKEAEEVAPGITVRNTTEPVTPTIPTPTATTGAASVITSRPLTIQRPTSHPLTQRPAPSAAPPVTSAPPVSSPSSMEPPSTPASPVPPTPPSPPTRPTRPPKPTKPQRPTTRPWWASAYTTTPTPSEERVTTETATPPPPTVPSTLPPTTTTTRRTTTRAPTTTTRRPTTTRRPTTTKRTTSSTTTSTTTTTITTMTTTTTPLPPTTTAGATSPSGPLVSSAHTKHECGVPSILPQPEGRIVNGSNARFGEWPWQVSVRRISFFGFSSTHRCGGALLNDQWAATAGHCVEDLLVQQIRIRVGEYDFSSVREPHPYVERAVKRKEVHPKYNFFTYENDLALVQLEQPLQFLPHISPICLPGNNDLLIGERGTVTGWGRLSEHGRLPSVLQKGSVPIVSNAKCKEMFLEGGRREHIPDIFLCAGYEKGGIDSCQGDSGGPLQVRGADGRYFLAGIISWGIGCAEPNLPGVCTRISKFVPWILDIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRS7</accession>
    <name>A0A423TRS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001282">
        <property type="protein sequence ID" value="ROT79164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRS7"/>
    <dbReference type="OrthoDB" id="6370062at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019024328" evidence="2">
        <location>
            <begin position="19"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="569"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="593" mass="64555" checksum="63F1370E06B7F82C" modified="2019-05-08" version="1">MVIWLVSLFLNTVLECTAWPRSRSSRTSCRWRSTLDRGGAYEVTLAGPSPPPAATLECQAGSPCRVWFAGVDAPPAVTVRKGSNAIYEATSGPPPPASRVERLTSRDADARMDVEVASDKHVTRADLVTFSSDVATDADCESLAATPSKSGYSVAASSRGAGDWNFLVVGYDDDGALLEAGRAHVTLSDILLPRMTKVGTEALQSLKVETGEMDVKVNGFLCSASTVCYYLEPENILEPPEVCRMAAPNIEQCDMTAAYIQPESLIERSVQLSFTGVPEEDLMITADFSETSLTMEAKLYTNSEDLTPNPLTCEITGRSPKTCTFKVEPKVTEFKILLMALDSESTVKDSTVVEFEDFQTRIQQLTLDAIEVRWRASQNQEYDVEIVSETDGKIDSTSVICGGEKPEDSKVCLAYFFPLNLNKDYTASVRVQGDNKYVSASVRMQPVLETINIKELTLTTTGETRGLTVCFMESREKRKQNEGEKIVNKFVAVDANGRQVQMVSKSSHSSVSDVEEKLCLGPLPLDLDFNLSDKVRVLVSRENLDTQEILLSGDAELFVSDPPPKDDKVVIVISVVGVVVAVVAIGSLGAISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRW9</accession>
    <name>A0A423TRW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative gamma-aminobutyric acid type B receptor subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002073</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001275">
        <property type="protein sequence ID" value="ROT79206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRW9"/>
    <dbReference type="STRING" id="6689.A0A423TRW9"/>
    <dbReference type="OrthoDB" id="17569at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15291">
        <property type="entry name" value="7tmC_GABA-B-R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06366">
        <property type="entry name" value="PBP1_GABAb_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000056">
        <property type="entry name" value="Gamma-aminobutyric acid type B receptor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002456">
        <property type="entry name" value="GPCR_3_GABA_rcpt_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF77">
        <property type="entry name" value="GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="784"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="821"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="854"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="955"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="996"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1019"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="12">
        <location>
            <begin position="787"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="401"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="455"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1063"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT79206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1162" mass="128760" checksum="82907D6894841196" modified="2019-05-08" version="1">MHVLCVSETFQAHKRGPGGEVSDGCVCEAGEPKERQTPPVSAGNCLRHARSLSISSASKYEGVCMGVGGRGGGAGGGRQRGAAAAHRGHLPHPRLRRLMPRQEVVLEPHPDTWTPQHIVPSFKGEISFAGYVRYCGSSLEAETELEYSNVSSYSSGFRCACQPAAMLALEDVNNRPDLLPGYKLNLAWNDSLCEPGLGAAVMYDLLYNPPTKLMLLGGCSTVSTTIGEAAKMWNLVVVCWGVGEWGRGWGLSGFLKNNSGFLTPFPTLVLFLLLLPPSLFPSPTSSLLLLHLASPSPLSTDPPLPLIPPLSLSFHNLPFPPSHLPLPSSFHTIPLPPTPSFSLPSPFITLLPPLSPSPHPTFLTPPPFSTLPLSSSPPFLRPSPFLTPFFTIPPFLPPPPSSPLPIPSPLPHAPSTLPHPPPPPSPPSSSPSPSLTFLPPPPALLRVELPSAGRQEPLPDLLPHASLGHGAQPAQDQDHAETVEDLEVRCKEAGIEIVTRQSFLSDPTDAVRNLKRQDARIIVGLFYVVAARRVLCEIFKNKLYGKSYVWFFIGWYEDGWYEQHLQEEELNCTREEMRLAAEGHLTTEALMWNKDMERTISGMTVGDFRRRLNQALIDNGHRNGSTPVGYQEAPLAYDAVWSVALALNRTMERLAARNMSIEEFTYTNKEIADELYSAMNATQFLGTRRDPLSRRRDINANRTIRRKPHLNPPITPQGRVAFSTDGDRIAWTQVEQMIDGKYKILGYFDGQTDNLTWYNVEIWVDGKAPPDRTIVRPQLRTVSLGLFISMCTISAVGAVWALLLLVFTFADPDVPPACNNITLVGIILCLGSIFLLGLDGQFVSEQKFPSVCGLRAWCLSLGFTLAYGAMFSKIWRVHRLTTKTKTENKRVEPWKLYVMVGSFVVVDVIVLGVWQGVDPQQRTLEVFPLEVPRDTVEDIKIKPELEHCESHHNTIWLGLLYSYKGLLLIFGLFLAYETRSVKLKQINDSRLVGMSIYNVVVLCLITAPVTLVISSQQDAAFAFVSLAIIFCCFLSMALVFVPKIVEVMRHVERAESTVDGAPSKEEEERYQKLLRENEEMQRIISEKEEKIRLLKLKLQERAAIRSREQQAAENHVTAVDATQQMRLRQGGRPAVRIVTPEGPGADESMVPRINFDISESYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTU3</accession>
    <name>A0A423TTU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001177">
        <property type="protein sequence ID" value="ROT79894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTU3"/>
    <dbReference type="OrthoDB" id="204305at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="39910" checksum="4D8496CE5B9E4F76" modified="2019-05-08" version="1">MPNPAPKRWCSLSQPWGGKGWIVPSAFPGVAKTSKMKGLFPGWAAWVYTDPRGREDVLCPLLQDFPYLYVCDVTNLPSFGDVTSIHNMVWRALPLGDARVSAFVIRDSDALVSSAADARAESEVALLERDAEAVKEWLSGNKNFHLLRDHPWHTALIMGAVGGARAGPPGGASQTVARSGQRRRRAGGQRKVQEGRRPVVAEESAISEDERRPGGSRQLLLHQVPRRFEALPDAAQERHVRRQLHGRQGSRPSAREGALPRGMPPEEPSGLDLLLIGPSSDESVTISCPQTLIDGHGLVWINTIRKVSFKTSITGHSFHMLSSPARSALLSAKWREGVSASNVSHVIEFGNIAEDIRGSVDQKSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWN1</accession>
    <name>A0A423TWN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative histone-lysine N-methyltransferase MLL3 isoform X7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001055">
        <property type="protein sequence ID" value="ROT80878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWN1"/>
    <dbReference type="STRING" id="6689.A0A423TWN1"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="780"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="819" mass="84756" checksum="D22845568A860525" modified="2019-05-08" version="1">MFRSGRVNIPQGGSARDIPGSSSPLPSSPMSVESSSTPQPPLSPPSGTTTPGQTPSVVSSLASSSTLRTVNTGSQSGSLTGPNSSSSSSSSSSSSSSSSSSSSSSSSSSSSNSSSSTGSSGNTIETSLEACSLAASATTMKVAGVQTSPPGTNPLQSGLNPEQQRALKSSESLEGSSTPGSVGTPGSLTEGTNTDPSPASTPHASPRPPLPSITPPRPMIVTQRPQIPPGSPTMRPGLAHTMIRGPMSHPQGPPDPYAMQPGTPHPNKQADPYAHPPSTTRPQTSPLPSPTSGDPFSRVPPSPRPHTSDPYSIPPSTPRPPASDPYAMPPPTPRPMDPYASQPATPRTPMSSDPFTPADSFSQPPSSGYIQAPPTPRPHSDDSYGQPATPAGGISDRGPSSGVRAVWFTQVVWLSQSHLPMGVMQSSDSRFHQWCRALVHVVQQRPHQQYMNVGPGVTSVCGQRSPTTVMVSQGMGSPHISAAGPVPVPVESPTHHPPGPPHPLAQTQGQGGDDLEDLGTGDLTTMEDDLLGMGGDFNALLEFADGEDGEEDDEKLPSNLFNVLDADEEERRKRNKSDEAGPGVPGLAKEKVSLPTTIPVGPPSSGTHAQPCPTVSPSQGSQPHLPNPVNSNCGPRGRVPVALQNLGPNAQQQRLGPIMEPGRAPMPHSQSMAPTTGSAPVSVGPSECSNMPTPPNMVPIGPSSGPPAGPPPGPIMGPVHMNISSAPQQPVQPQMATHITQPSARFAGMARMPGPRGGMIRQPAPPPPPYPGHPPPPPYPRTQVSEDWHVEAWMSFSCCGWQYVAWCRDILYSVLILGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWW2</accession>
    <name>A0A423TWW2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001043">
        <property type="protein sequence ID" value="ROT80968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWW2"/>
    <dbReference type="STRING" id="6689.A0A423TWW2"/>
    <dbReference type="OrthoDB" id="823504at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF106">
        <property type="entry name" value="CURLY SU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019048693" evidence="2">
        <location>
            <begin position="25"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="52057" checksum="7FBE1E73C7AA3D0B" modified="2019-05-08" version="1">MSSYFVVSAQIILITLCLLTKTEAKFNAQKRSRSLVPTRPDSRLNCLLNDLLQFPGGSCITHQAVDAAFESALAARGILRGPVGEWEPEDIAPLGDVILDTARILARTYKLSAEEIWTLLPKVDVGETLVAKYCPDFASPMTCVPGRYRRHDGLCNNLRFPTWGATRTAFARLVPPAYSDGLGAPRVSRIPGGSLPNPRRVSSSIHRDKGYHDHAITLFGIAWGQFMDHDFTLTATPLDPLTRNEPEVCCHPPPGVPKDPHCLEITIPKDDRFYKLYGQSCLEFVRAFSGVRQDCKLGPRAPFNILAGVIDVNTVYGSTDKHARSLRSFRGGEMRMNNAFASLGLRALLPQKLDVPDEGCTRTSPHQYCFDAGEIRVNEQLILTTMHTLWFREHNRVAGRLANLNPHWDDETLYQEARRIIIAEVQHITFNEFLPLLLGKEVMAEYGLLPEKEVITTAMTPRRTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0G7</accession>
    <name>A0A423U0G7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_024654</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000866">
        <property type="protein sequence ID" value="ROT82181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0G7"/>
    <dbReference type="STRING" id="6689.A0A423U0G7"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000600">
        <property type="entry name" value="Contactin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="110"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="203"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="291"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="391"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="9">
        <location>
            <begin position="503"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT82181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="69094" checksum="AB19C0FDB27C3913" modified="2019-05-08" version="1">MFLKVFVRGPPVITEHPSNVVARRNDPATLNCAASGASRIRWYRDGEEVTTSTVDTRSHRVLLLSGSLFFLRVTATRRDNDAGTYWCVASNSYGATRSRSATLTVAFLADEFQAEPQSSVKVRVGEPLILPCQPPKGSPPPELTWLRNGEEVTNSSRVNVLAAGDLVISQVVEEDSAVYICRARNAAGSRESEPSKVIIMTPPWFEERPANVTVASGVVVELACRARGSPTPTVTWRRLDGKMPLGRAMIEDQRLVLDHVAAADSGVYVCEVESEAGIAAARATLTVVDAPELTQKPQDVQVVSGERAKLSCVVNGDPKPLVLWRLPDADKTALLSAGQTSGRASVDGSSHTLLLQDVTTEDSGAYHCWGISNGGGVTARAEVTVVSAHPPPVVGVGPEDLKLVPGSIASFPCEAVSEAATPTITWWYRPAAHLPARQLTDEGDDARISLPTNGALILKDVRADDAGIYTCHITADTGSVEQAAILRIVDEPSLQESFLLPAPPSKPRVVAINETAVRLSWLPNSRVSESSSQSYTVEYWRQGWEEWRVAEALIPQETCVIGDLAPGYTYTFLVRAVAERGASFPSPWSDPVRTRSPRDPALSEDHPLRLCARVRRVTVCTRPRCLDPWGYSLEECHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0H4</accession>
    <name>A0A423U0H4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C1q domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024614</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000857">
        <property type="protein sequence ID" value="ROT82219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0H4"/>
    <dbReference type="STRING" id="6689.A0A423U0H4"/>
    <dbReference type="OrthoDB" id="6360045at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Adipolin/Erythroferrone-rel"/>
    </dbReference>
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        <property type="entry name" value="Tumour_necrosis_fac-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24019">
        <property type="entry name" value="ADIPOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24019:SF5">
        <property type="entry name" value="ADIPOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49842">
        <property type="entry name" value="TNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3" id="KW-0732">Signal</keyword>
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            <begin position="52"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="39463" checksum="721A33F96F40ED11" modified="2019-05-08" version="1">MRIRGLSHVTSPRPVKVCVIHYRGASVECRPLLREPPQPPRPRPSALRRRLASQPGLAVGRPGAAAPGARLTCAEGEGPRLADEPPPPRRIFSFCNQSPQTVPRPLPQPPHVHDPKETFRQFLHHSERQRARRRQMKKNKRKNQIPMPRVGPPGPPGPRGPPGPAGEAGGALTTGEMEAYITDFLREFFQQHNDTVHVPESLERAEKTRRSRVTVAFTAHLPHPATLRPSVLSVVDTFTVTFAPGAFERRVVVEHGGFTVTKSGIYQVAASLVLHPRGPSHSALKPLKDIRVYVCVTVCDRDSRRLEWVGNVGEGSVTAVLSGHIMLRRGNTLLVAVDNLSRRPLQVGTGSTFSAALIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2T2</accession>
    <name>A0A423U2T2_PENVA</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023794</name>
    </gene>
    <organism evidence="3 4">
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        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
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            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
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            <taxon>Multicrustacea</taxon>
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            <taxon>Eucarida</taxon>
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    <reference evidence="3 4" key="1">
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            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000749">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2T2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <end position="77"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="117" mass="13258" checksum="6C0DD524593EA6DA" modified="2019-05-08" version="1">MVYSGHARRLPSKEHIKAGPQTTASYFSSSKATNNTRTRTLTLPISTVQASATKMRFLFVLIVACSLLGTALSMPQFRDVRNEVASNFFIRPFFSRNQRLRPARRQPYVMDDFLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8B0</accession>
    <name>A0A423U8B0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcification associated soluble matrix protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000462">
        <property type="protein sequence ID" value="ROT84954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8B0"/>
    <dbReference type="STRING" id="6689.A0A423U8B0"/>
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    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
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            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
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        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="11503" checksum="35C660AB73481B79" modified="2019-05-08" version="1">MKTAVLLLLVAAALADKPDSEMAILRSDQHHPNDDGAHSFDFETENGISFHVSGSQGATGGANSIGDWSQRQRPPPPPAASVRLSASRRNRPGSETTSPAQAESLAGSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTA0</accession>
    <name>A0A3R7LTA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003376">
        <property type="protein sequence ID" value="ROT63799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTA0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="890" mass="97863" checksum="C9CA6DD35AE7C92B" modified="2019-04-10" version="1">MLPYYPSCPPRCLSDIKPPRQPNQATSQPPKRRTILISNQVASQPPDQPLAQTTTKSTSLTLKTNHPNHAATPPHKTTHPYHAATPPQQQHHPNHGGNPPKPRSNPTPTTTPTPIPRQPPPPPTTTNPHPPPQPRQQPHPTAATHQTTQQPPPPTPQPTQTTAHSATHLNHAAPPQQPPNHAATHPNHPQQPPPPPQTTPKTNAQQHTPPPTTTPPRRQPTQTTQATPPNNPPQPRGKPPKQQPQPPNNPPQTRATHPNHAQPPPNHPHPPKPRATPPPTTHPNHAATQPTTPATTPQPRGNPTNHAAPPKQPPQPPKQPPPKPTPNQRNPPTNQFPPNHSEPPPYNHAATHPNTPATPTTHPPTTNPNQRKQNPPQQETLPQPRGQPPPQTTHPNQRSNFPTPQQTYPNHHGNPPPNAKQPNPTATNPPKPPQQPTPTTRNPPKTIQQPPPPQTTHRQPTRQPTQTTARQPPTYHPNHAATHPNTRQPTQTTQTITPPAQTTTHPNHAATTQPRSNPPNNNPPQPIQRASPLHPSPYFSPNTTTLPTTRSATLTTPPLSCCHIPSSPPTHTIQPLSTQSTRTHTYITTLCQAHFQYLRCWSKPTSHPRERNSPSPLNQQPPHYIAPSPKPSLPPLSSATIQVKTKRRPEQPASRAPGPGLSSPLHRPSSAVEWEARVEAHKSFRVGELQDARLIIFSPIPLFLFHPSCPYPSFFLTLPSSLFLFFPSLLHNHSLLILFFQSPSISFPSSPALLQSSLALTIGRHFPLTPAVPPAAAGPPPPPTCVGVHGKKPIWTPSRKILVRWISHSQWRGYLRERLSKVLETDGSRSQSEGEKAPEIILWDEILKMSENIRREGRKHWARHHERTLSVTPVVATPFAEDTGPASSWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUD7</accession>
    <name>A0A3R7LUD7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycoside hydrolase family 31 TIM barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003233">
        <property type="protein sequence ID" value="ROT64560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUD7"/>
    <dbReference type="STRING" id="6689.A0A3R7LUD7"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="4">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="4">
        <location>
            <begin position="152"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="278" mass="30721" checksum="63315383BB9669C6" modified="2019-04-10" version="1">MNEPANFGTNEQRPWNCRRSGGPGASPAPPPLPSRSFPQPTAPDPCLPTRLSDKTLCMVARQGEERELRHYDVHNLYGWSETKPTLEALQAATGKRGFVVTPVDVPEQRQVGGALAGGQRANWNHLGDSITGEGEGEEREKGEGREEEDVAGIHLFGIPTLVADICGFSTTQETECWNSTCSEYPTLVRIFADSSTTQKRDCERWMELGAFYPTAGATTPWRERPCMLGMMDPGLWPSVAASSRKALRIRYTLLPYLYTLHFLAATTGSTVVRPLFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWL4</accession>
    <name>A0A3R7LWL4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">U2A'/phosphoprotein 32 family A C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015513</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002932">
        <property type="protein sequence ID" value="ROT66454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWL4"/>
    <dbReference type="STRING" id="6689.A0A3R7LWL4"/>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097733">
        <property type="term" value="C:photoreceptor cell cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000094">
        <property type="entry name" value="protein C21orf2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="437" mass="50054" checksum="F17CB22181338ECC" modified="2019-04-10" version="1">MVKLTEDMVVARSKGSDLHNVRKLNCWGSELSDVSVVRKLPNVEVLSLSVNQIQTLADFQYCPNLQELYIRKNSISDINEVLYLRQLPKLKSLWLADNPCADFEKYRHTVLRALPHLQKLDNVAVDSEEVQQAMVCGLALPISDSPMAQREEREMPRSSSMGESLRSEGGSSLSDCSPPSSERRYSQTTTPTRSNQQAVYDEDDEQPVARRTSYSQYQQSDPERRISQMSHYSNQDTSPQSPSRRSSQIVTEADSSDSRGYIRSPESRTHNADYEYDSRNANYLSREDTAPSRRPGQEQYRDQRWSEAEERERGYSRGDGYGYASPPSEVRQSPVGYEQRISQDPRYEPRTQSRQSENGLVQQHYDNTYRRVEQQVETASRSSAMERPSPTKPYPARPKTRNANVLSAVLCLIKELDYSSLEVVEMAVRCRMEELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYQ0</accession>
    <name>A0A3R7LYQ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Double-strand break repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_015072</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16 18">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002879">
        <property type="protein sequence ID" value="ROT66880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYQ0"/>
    <dbReference type="STRING" id="6689.A0A3R7LYQ0"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000011">
        <property type="entry name" value="Double-strand break repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16 18" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16 18" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 16 18" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 16 18" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 16 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16 18" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 16 18" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16 18" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 16 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="20">
        <location>
            <begin position="291"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="507"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="545"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000882-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT66880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="611" mass="68984" checksum="A872C9149D978EC1" modified="2019-04-10" version="1">MGSTLDDTFRILIATDNHLGYAEKDPERGNDSFETFEEILKMAVEQQVDFILLGGDLFHENKPSRQCLVKCMELLRKYTFGDKPVCFEYISDPTENFKNSKNPMVNFHDPNLNVSIPVFSIHGNHDDPSGLGQFCALDMLSTAGLVNYFGRTGDLKNITISPVLLEKGTNKLALFGLSSIKDERLFRLFKENKVKMMRPKEFHDEWFNIMVVHQNHAKHGMSNYLPEAFLDPFLHLVIWGHEHECLIQPRLSADNSFHVVQPGSSVVTSFCAGEAVEKHVALLEVNNKQLFNVTPLKLETVRPFVFDDVCLADQDLDYVIGNKERNPVEEFVEEHIRGMILQAKEQLTGHPKQPKKPLIRLRVVYTDESQMFNTARFSHKFTEDVANPNEMILFKKERKEKKKNETGIDKEAMDAVFAGEDVAETRVEDLVEQYFSELQDYTQKLFLLSERGLAKGVNTFVEKDDRDAISTVFQHQVKKTVDHILSGDGDIDEENILDAIITYREERLTKNNPHPPPARGRGSRGGRGRGSRGSRARAASSSASTTQTSSKNQLSMIGDGSPKVSQSSTRARASRGRGRAATRNQSIMESFSRARTAASSRKGIVYDSDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZG7</accession>
    <name>A0A3R7LZG7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase-like protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_013056</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002635">
        <property type="protein sequence ID" value="ROT68764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZG7"/>
    <dbReference type="STRING" id="6689.A0A3R7LZG7"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF5">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT68764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16581" checksum="73CAD9C6A8D87EF6" modified="2019-04-10" version="1">MACPESGALGHHLRSLTPEEEQKLKQQESRGLLSEFLQKKLEQEAAKNWDKFYKRNETRFFKDRHWTTREFQDLIGDGAVKRTLLEVGCGVGNFFYPLLEDGLNLFVYACDFSPRAIEFVQSHPMYDETKVCAFHCDITEVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZP9</accession>
    <name>A0A3R7LZP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014266</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002785">
        <property type="protein sequence ID" value="ROT67644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZP9"/>
    <dbReference type="STRING" id="6689.A0A3R7LZP9"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02872">
        <property type="entry name" value="GH18_chitolectin_chitotriosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000001">
        <property type="entry name" value="Chitinase 3-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF360">
        <property type="entry name" value="CHITINASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018766609" evidence="8">
        <location>
            <begin position="20"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="19"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="9">
        <location>
            <begin position="403"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="367"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="469" mass="51833" checksum="E11D0B7AC648C435" modified="2019-04-10" version="1">MRILLLLPLLAASLSLAEGVMVCYFGSWAVYRQGLGKFDVEDIDPKICTHAIFGFAGLSFTALKQQNANMKAILAVGGWNEGSAKYSTMAADPARRNKFITSSIALLKKHGFDGLDMDWEYPTQRGGNPEDYDNFVILLAELKAALSAEGMILTAAVSAGKGTIDPAYNIPEMSKSLDLINVMTYDMHGAWDDYTHHQSGLYAHPLDEGDNLYFNVDFAIRYWIEKGARPDQMALGIPLYGRCWTLASQQDTGYYAPAHQPGAAGDWTRSPGMLGYNEICYMQSTQDWTVVNDPAMNEPYTYYFPMNNIWCSYDHEASVITKAKYAKDMGLAGTMVWSVETDDFRGLCHSRTFNLIKTMVEAFGGGTITEPPTLPPQSTTTRDPSLPTVPPTTTTTYKPPPPGEHCSQPGLNPDPIDCTHYYLCSISITGGYDELEQVCPEGTLYNPQSFICDWRDSVCHLGDVCPNDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0I9</accession>
    <name>A0A3R7M0I9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Embryonic gonad protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018081</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003345">
        <property type="protein sequence ID" value="ROT64003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0I9"/>
    <dbReference type="STRING" id="6689.A0A3R7M0I9"/>
    <dbReference type="OrthoDB" id="5850793at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050200">
        <property type="entry name" value="Nuclear_hormone_rcpt_NR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001628">
        <property type="entry name" value="Znf_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48092">
        <property type="entry name" value="KNIRPS-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00105">
        <property type="entry name" value="zf-C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00047">
        <property type="entry name" value="STROIDFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00399">
        <property type="entry name" value="ZnF_C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00031">
        <property type="entry name" value="NUCLEAR_REC_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51030">
        <property type="entry name" value="NUCLEAR_REC_DBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nuclear receptor" evidence="10">
        <location>
            <begin position="159"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="282"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="392"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="479"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="404"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="589"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="624"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT64003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="699" mass="74521" checksum="F826142203EB39D2" modified="2019-04-10" version="1">MATLRPRPYEVIGRYRGYGRSYLQHFDPLHLGPGDTPAAAFPTTMQGKHAYALSATYAVRSRVFAAGGRTAQTAWRMRAIPGYVAANGVPRNNLRRRTGLAEDVAGRHNRRVTATASSSQPSPIDINLTERFHSQLATAGSSRHDPIVMNLFSSFCRMNQLCKVCGEPAAGFHFGAFTCEGCKSFFGRTYNNLSQVHECKNGGQCVINKQNRTSCKACRLRKCLVVGMSKSGSRYGRRSNWFKIHCLLQEQAAQINNGLDGGGGGGSFPGAVAGSLSLSPASMPALSPAKSEDEAKGESPALSSPESCLSETSIDVEPRRTSSPKDMSVVEGGGRGAERFGEGGRRDLAGAAGLSLYGLHPGLSLLHASHLYSRLYPPMLYSGIPPSLLVPPGVPRAQPPSSPPKEASASSPRMCSPHALSPRHHSPRPHSPPRPLTPPVRPMSDYRSPLAPPLALHLGFPFARKRVADSPVEEMRAASLSPQAWEATPAPEQEAPIDLSVKRPRLLAPSPGTPTPVSPPVSPVLTAVPTSTAPVDLTTKADSPSSALPRDSPPPPPSSALPRESALPRDSPSSALPRDSPSTALPRDSPSSALPQDSHSSALPRDSPSSALPQDSHSSALPRPPRRRTSGRPRRTLVWNTLSLLPGHSWAPYGPRLRHVLFVYGPCLTRSALAGGGPQLQLGRYTLLAEAASRPFLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3I2</accession>
    <name>A0A3R7M3I2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3I2"/>
    <dbReference type="STRING" id="6689.A0A3R7M3I2"/>
    <dbReference type="OrthoDB" id="10261522at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044715">
        <property type="term" value="F:8-oxo-dGDP phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03676">
        <property type="entry name" value="NUDIX_Tnr3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000019">
        <property type="entry name" value="Thiamin pyrophosphokinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031804">
        <property type="entry name" value="DUF4743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15916">
        <property type="entry name" value="DUF4743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="133"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="324" mass="36383" checksum="8915F33EA06D9179" modified="2019-04-10" version="1">MLSLPPTDGCHGNKILRWSSLTIRLVSVQGECRPLITCGRQVGVIRPDVACCLLDYPQVFTATPDAFIINPQLNSYASRSSALDYVLRDLRAKNVLLALRGWREECFNVWADFGAEPLFKIERSAATVLGVRAYGVHVTGYTYRDGKMMIWLQKRSIDKPTYPGMMDTMVGGGLTAGLKPSDVYLKEAYEEASLPEHLLKNGRQAGTVAFFTESERGLHANTEFVYDVELPSDFTPSNNDGEVEGFECIPVEELLERATSSKYKLTSVPVAVDFLVRHSYITPETEKEFPTLMELLHVPLNQLYRRWPHNRFQASPTPSLITDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6D8</accession>
    <name>A0A3R7M6D8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative transducin-like enhancer protein 3 isoformX5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_008338</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat Groucho/TLE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002050">
        <property type="protein sequence ID" value="ROT73232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6D8"/>
    <dbReference type="STRING" id="6689.A0A3R7M6D8"/>
    <dbReference type="OrthoDB" id="2624652at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000001">
        <property type="entry name" value="transducin-like enhancer protein 3 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009146">
        <property type="entry name" value="Groucho_enhance"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10814:SF21">
        <property type="entry name" value="PROTEIN GROUCHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10814">
        <property type="entry name" value="TRANSDUCIN-LIKE ENHANCER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01850">
        <property type="entry name" value="GROUCHOFAMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="163"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="205"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT73232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="363" mass="39228" checksum="4DBB209AE74A83E7" modified="2019-04-10" version="1">MGLRHGTCFGSGYDPHGVRPPPLASNGIPTNGSAGKPAYSFHVSGEGQLAPVPFPSDALLAPGIPRHARQINTLHHGEVVCAVTISNPTKYVYTGGKGCVKVWDISQPGSKTPVSQLDCLQRDNYIRSVKLLPDMRTLIVGGEASTLSIWDLATPTPRIKAELISSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISPDGTKLWTGGLDNTVRSWDLREGRQLQQHDFTSQIFSLGFCPTGDWLAVGMESSNVEVLHVNKPDKYQLHLHESCVLSLKFASAGKWFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISADDKYIVTGSGDKKATVYEVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6E0</accession>
    <name>A0A3R7M6E0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_013502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002682">
        <property type="protein sequence ID" value="ROT68355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6E0"/>
    <dbReference type="OrthoDB" id="6329175at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF104">
        <property type="entry name" value="AT-RICH BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT68355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="90" mass="10482" checksum="9254342E6750DC38" modified="2019-04-10" version="1">MCPVCRFTTSCNLVLGQHMRRHAGGYPFLCPHCDYRTHRSHDLKKHLRTHTGEKPYHCTYCPYQTSDPSNLSAHLKARHAMVRLEDHLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6M3</accession>
    <name>A0A3R7M6M3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002659">
        <property type="protein sequence ID" value="ROT68542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6M3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="104" mass="11659" checksum="AA459B19E86EB6B5" modified="2019-04-10" version="1">MTTTAQIRCEIMVNLYLFPLVCVVFLPLCYSSEYCEYPLLDEASLRASSELHTREADKAKLNTGTKEPSLGPTEYPVRGLTQTFRVQPTHEYRVPAPHASPLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9D6</accession>
    <name>A0A3R7M9D6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_011056</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002402">
        <property type="protein sequence ID" value="ROT70641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9D6"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000075">
        <property type="entry name" value="Putative zinc finger protein 536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000992">
        <property type="entry name" value="Zinc finger protein 320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000052">
        <property type="entry name" value="zinc finger protein 546 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000634">
        <property type="entry name" value="Zinc finger X-chromosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409:SF434">
        <property type="entry name" value="FI01124P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24409">
        <property type="entry name" value="ZINC FINGER PROTEIN 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="407"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="437"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="485"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="513"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="541"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="570"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="626"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="222"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT70641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="838" mass="92835" checksum="F05FA789E0600CBB" modified="2019-04-10" version="1">MSESEDGTILGGSGPLEMNVVSLPKMDAAQLDQLGLNGPGGTLTTTGLTSLGAASQHYAPAPSGGTQALLDGVMAQGSRTLSSVSPAVTFTSAGGSAQDSYGSLEYVTQMPLPDDQQAKFPDALVSVDNVAFVEMNDAAMKGATASAPLELYFDVINPTTTPAPTTSSAHHLMPLVSRSGRPIRRRPEYVEYVSQNLKEEEILPHLPQQLVKVEDMVITAEFEEEDPMEEVMEEEDPLEEDLDSNDEDQDNGGNYSTDGKKSLPHKKRIPKKLKTTKKHVKCYKCAQCGEQFTNQQQFTAHKQTHTPPPAKPKPFSCEICSKGFETQLKFFEHLKGHYEPYKKHKCEVCGGEFESADALQEHSMVHSREHYKCELCNKTFRKESMLEVHLKVTHMEEDESSTVEKPYTCLACPKSYRTQMALDSHVQTEHSENPPEFNCEDCYRVFKSKSKLMTHRKIEHKEEGPQNKGAPKKKMKIGKTVKGGYACTMCPRVFTHKNSLVYHIRGHTGERPHQCEQCGKAFYAASALKVHLRLHSGEKPYKCEHCGKFFRQWGDLRYHTTSVHSDARQYQCEFCGKDFKRKYCLVVHRRIHTGEKNYKCERCDKAFRAASYLQNHKRIHTGERPHPCPDCGKPFRVRSDMKRHRQTHMREQANANNTVGTPASTAVTQVGTQSPSPAPHAQIVSGAVSQGSSTPQLIVADQVTGPDQPIRIMVSGLNAQHVATAVHPPPAHRQPQQVAVPVSGNIATLTTGPVSPGGTTTTLTPEVIIMDDNAHQPINLNIIPRMITQAQVGSSPHASHATLVTTEDEYQLANPGRNTIEVRGEEGNVYVWHGVFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ME47</accession>
    <name>A0A3R7ME47_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007587</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001962">
        <property type="protein sequence ID" value="ROT73944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ME47"/>
    <dbReference type="OrthoDB" id="6381414at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="3">
        <location>
            <begin position="495"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="608" mass="68267" checksum="4CAA4704DF812313" modified="2019-04-10" version="1">MGRRNCGSRNNSPSRPSTSQEAASAPSVGRNSPSGQTLLPDSDDRGIERLPEISNSELEARISRPSTPVSVREAPPVEFVVQRDPIPQFKAEVSSAHPLKRNQEVESWLRSVENHTRPQTDAAFIKTAKASCKGAAELIVNSLLFDSIVSWVEFKDKLRQKFRVTGTSSDFYRVLQSQKLQPGQAPMDFYLTLEGMVYQGLRDYPRAIGDPDDLIRRVFLQGLPRWIREAVVVKEEAELCNLVETTQRVWSLRKSKGPGVSSPTWLPFRPRVLAAGEQPLIARRRFFGNLQVAHVAVPAFVPPRSGRFVKCSVPRGMQAAKELMVSGTECPLVVPRSLQEYAAEEQALGTEHFMGNDNDFELREGFIDDDFDSFDAVGDFGSADDYIILSDVDLPPCSVVTQTPAGVDQSGSRNHRAPDQLSRAVAATELHNRDPDDLRRHQLEDPLWKEVIEYLEERYLPRRRLPLTLEEFELRDGILYHVRHLPDRVLHQLVVPKTLRGSAMHLVHSSATAGHPGVYRTYCKLRDYFYFPNMLAAVKEYVGTCRSCQKRKGMAYRAPLAAAPQASYPLERVSADLMELELELGFHRPTHPIRSVDTSAIQGCRDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MH18</accession>
    <name>A0A3R7MH18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone-lysine N-methyltransferase PRDM9-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001672">
        <property type="protein sequence ID" value="ROT76324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MH18"/>
    <dbReference type="OrthoDB" id="10572323at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003655">
        <property type="entry name" value="aKRAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14112:SF1">
        <property type="entry name" value="KRAB-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14112">
        <property type="entry name" value="SYNOVIAL SARCOMA, X MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21549">
        <property type="entry name" value="PRDM2_PR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50806">
        <property type="entry name" value="KRAB_RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="KRAB-related" evidence="2">
        <location>
            <begin position="35"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="496" mass="56118" checksum="148682FE458B3DD2" modified="2019-04-10" version="1">MRQAQDPRKSAQSDSLGIRSTIRRWVRGTFRLLGRKRAMAEDAKQLFSTEEWLSFPEIEKNRFENILRNYKAMKDFGLDPKLPEFVVRQQRRRRNGLVAPTVRPPRVPDDEGDDEWTPEKERSSRYASKSGSVGGGRRGGLKRKAEWSAPAWTGRSENYDDAPLSVDQVDVIPLWTPAKLVAGAKGTVKIMPTTSDRSSGDSALENVKPEDKEVFSVPMSQLTTDTEMVTVKELPAKSETLGVGSDEEDCADCEEEKEGECSYHPLFLILEPRCSRRQRERSCSPHNPLAPHCLRLEVKGAGKGVWTNAHLPAHLVFGPYEGRVLSGHPEAGKESGYGWKIRGTGTRNTCIDAVDSAVSNWMRYVNCSRTEAETNLSTFQYKGQIYYKTDSAISRQAQDPRKSAQSDSLGIRSTIRRWVRGTFRLLGRKRAMAEDAKQLFSTEEWLSFPEIEKNRFENILRNYKAMKDFGELCRCECPFHSRRILSGIGLFSGVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHK1</accession>
    <name>A0A3R7MHK1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Paramyosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_024892</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000903">
        <property type="protein sequence ID" value="ROT81947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHK1"/>
    <dbReference type="STRING" id="6689.A0A3R7MHK1"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000008">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000025">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000009">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="12" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="10" id="KW-0518">Myosin</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="17">
        <location>
            <begin position="61"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="100"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT81947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="586" mass="67393" checksum="D2DC2C5F0A5A90F0" modified="2019-04-10" version="1">MLISFVSWRRLRARSASFPESSSLLRISSMTPGNSLKKRAGHVPHSLVSSATWNTTFRLFRQQLDEENEAKGDVLRMLSKANAEALMWRSKYESEGVARAEEIEAARMKLAARLEEAEMQIESLNVKNLHLEKTKMRAAAELDDLQVAAERAQTLANSAEKKQKNFDKIISEWKLKVEDLAAEFDASQKECRNYATEHFRLKAANDENIEQLDAIRRENKNLNDEIRDLMDQIGEGGRAYHEAQKNAKRLELEKEELQAALEEAEAALEQEENKVLRTQLELSQVRQEIDRRVQEKEEEFDNTRKCHQRALDSMQASLEVEAKGKAEALRIKKKLESDINELEIALDHANKANSDLQKHYKKIQDEIKSMESRVKEEQRLASGYREQYGIAERRFNALYGELQESRTLLEQSDRGRRHAETELNDAREQINNLTTQNAALTASKRKLEGEMQTLQADLEEMLSEAKNSEEKAKKAMLDAARLADELRSEQEHATNQEKMRKALEGTVKDLQTRLEESEAAALKTGKKAVSDLEARIRELEASLDDETRRHADAQKNLRKCERRIKELAFQTDEDKKKPRQDAGPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHQ4</accession>
    <name>A0A3R7MHQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003863">
        <property type="protein sequence ID" value="ROT62036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHQ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="42379" checksum="48B30FC852CF4FF9" modified="2019-04-10" version="1">MSKLPHPPMLQLPHPPMSKLPHLPMLQLPNLPMLQLPHLPMLQLPNLPMLQLPHPPMSKLLHPLMLKLPHLPMYPIFQCCSSPILPCCSSPILLCCSFPIFLCCSSPIFLCCSSPSSYVAAPPSSYVAAPHLPMLQLPHPLMLQLPHPPLLQLPHLLMLQLPHPLMLQFPHPPMSKLPHPPLLQLPHPSMLQLPHPLMLQLPHPLMLQLPILLCRSPPSSYVAAPPSSHVAAPHPPMSKPPSFYVAAPPSSHVAAPPSSYVEAPPSSHAVALPSSYVAAPPSSSVAAPPSSYVAAPPSSYVAGPPSSNVAAPPSSHAVALPSSYVEAPPSSSVVAPPSSYVAGPPSSNVAAPPSSHAVALPSSYVEAPPSSSVAAPHLPMLQLPILPVALPSSYVEAPPSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI68</accession>
    <name>A0A3R7MI68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative low-density lipoprotein receptor-related protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_024484</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000837">
        <property type="protein sequence ID" value="ROT82372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI68"/>
    <dbReference type="STRING" id="6689.A0A3R7MI68"/>
    <dbReference type="OrthoDB" id="10055367at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005041">
        <property type="term" value="F:low-density lipoprotein particle receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF5">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018540014" evidence="12">
        <location>
            <begin position="37"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="52"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="74"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="199"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="217"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="267"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="361"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="399"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="418"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="455"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="476"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="495"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="572"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="579"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="609"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="628"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="669"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="676"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="688"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="709"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="728"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="746"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="753"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="765"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="840"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="847"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="905" mass="99131" checksum="29650D11E9229A82" modified="2019-04-10" version="1">MACGSVRHQPRASKPSSWRSAAAALLLLAAFGLADAWQPDEDLTFDEAAVGVAGDDPGAEEAPVAPPYQEVHRAKAAPTKRQRRHSDDEDDVGSASGVLRTGEDCRGDDQFLCAGTDNIYVCDLHRCNKIKDCPLGDDEIGCGCDENSFMCDVERCVVYTKKCDGVIDCMDSSDEEGCACSASEFACLDGQCVDGRRRCDGEHDCDDQSDEVNCSECAGDAFLCGDKHCIPQENVCDGVTDCDTDEDCCGMLRCSSDGSCVAAGKACDGRRDCPDGEDEQGCPGETCQAGEYSCTDGDCIPVSQRCDGRAQCADKSDEIGCLCGSDQWTCNDGFCIPKEYRCDGVSDCLDRSDEKYCDAACRLGEWSCGNGLCIPRSQLCDGVPQCPDRSDEEDCLPACASTEWTCGDGTCIPLEGRCNGRYECRDYSDEDRCPACSPGEWTCMNGDCIPTAQHCDRIPHCRDGSDEENCPPQLACASTEWTCGDGTCIPLEGRCNGRYECRDYSDEDRCPELSLNDGRLGSRHANLFLLYSMQSWRVDLHEWGLHSHRSTLRQNPALDGSDEENCPPQLACASTEWTCGDGTCIPLEGRCNGRYECRDYSDEDRCPACSPGEWTCMNGDCIPTAQHCDRIPHCRDGSDEENCPPQLEGRCNGRYECRDYSDEDRCPACSPGEWTCMNGDCIPTAQHCDRIPHCRDGSDEENCPPQLACASTEWTCGDGTCIPLEGRCNGRYECRDYSDEDRCPACSPGEWTCMNGDCIPTAQHCDRIPHCRDGSDEENCPPQLGLSLFVHFSPSLRNFHAVRRVDLHEWDCIPTAQHCDRIPHCRDGSDEENCPPLPACASTEWTCGDGTCIPLESRCNGRYECRDLVMKTGVQKAVVTGVMSAETIVMKTGVQVRMLLHQNIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIW5</accession>
    <name>A0A3R7MIW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative hemicentin-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003478</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001469">
        <property type="protein sequence ID" value="ROT77819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIW5"/>
    <dbReference type="OrthoDB" id="6377396at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000129">
        <property type="entry name" value="CLUMA_CG018772, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF6">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 7, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00406">
        <property type="entry name" value="IGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="97"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="239" mass="26707" checksum="67ADAC26864461A7" modified="2019-04-10" version="1">MAYFDDDIDFNVSAIVGQQARLPCKVINLDKKDVSWIRQRDLHILTVGIFTYTSDDRFKVFHPEGSDDWFLEINPVTFRDAGVYECQVSTSPKIFLPVTLTVEVQHASIHGPKEIFIKNGSTIRLFCVINTHSENVGVVSWYRDTTKLDYDSPRGGVSVEIEKTPERTTSKLFLTRALKGDSGNYTCAPKFALADSVLVHIVNGEESAAVHTASSANLECNRLLLSSSLLVALLVRVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJY1</accession>
    <name>A0A3R7MJY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003398">
        <property type="protein sequence ID" value="ROT63687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJY1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="48081" checksum="DD55590B135CE56F" modified="2019-04-10" version="1">MQKREETPYINAGKKRGRNAVISHGRNGKKRRYWQKRKKRLISNWGRNGKRRYQPMAETGTPLSAMAENGKNAVSAMAETGRNAEHRNGKKRLQQCRNRNDETPLSAIVISNGRNGEETPLSAMAETGKKRRYQQSPYQQCRNGKKRRYQHGGRNVISQQKREETPLSAMQKRNVISHGRNGKKRRISNGRNGEETPLYTPYQPWQKREETPLSAQKRKKRRYQPWQKREETPLSAMAETGETPLLQNGKKRRYQQWQKQKRRYQPWQKRGETPLSAMAETGRNAVISHAETGRNAVISNAERNAVISNQGRNGEKRRYQQWQKRGRNALSITPYQAETEETPLSAMQKRGRNAVISHGRNGKKRRYQQWQKRKKRRYQPWQKRKKTPTIGSTLILNKSSIVPIVNAADTLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N377</accession>
    <name>A0A3R7N377_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine methyltransferase NDUFAF7, mitochondrial</fullName>
            <ecNumber evidence="3">2.1.1.320</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NADH dehydrogenase [ubiquinone] complex I, assembly factor 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein midA homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_005362</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 17">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001697">
        <property type="protein sequence ID" value="ROT76052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N377"/>
    <dbReference type="STRING" id="6689.A0A3R7N377"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00603">
        <property type="entry name" value="IPT_PCSR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12710:FF:000001">
        <property type="entry name" value="Protein arginine methyltransferase NDUFAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="IPT/TIG" evidence="14">
        <location>
            <begin position="648"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="999" mass="109858" checksum="F0013A43C6883344" modified="2019-04-10" version="1">MGTLARISRRLHYNCKNFLSPLQETRKEGVRVDINASLSTTSRRFDSPSGNDETGKQTNLSIKKTPETPLLKQLQARIKFSGPLTVYDYMKEGLINPLSGYYAAGQDMFGSKGDYTTSPEISQMFGEMVGVWIYNEWYKLGSFKPLQLVELGPGRGTLMQDILRVLGQLGVKGRDLSIHFVEVSPELSQSQEERLCGSSQPYTETNESYFYKKNTTTGGSPIFWYRHLSSVPKRFSVFLAHEFFDVLPVHILRRTKDGWRELLVDVDEGDGPHHLRYVLSRTETPASKLFVEPEETRDEVEVCPDAAVLCKDVAKRIEDNGGLALIMDYGHDGKLTDTFRAFKNHKQHHPLSEPGTADLTADVDFAYLKKQVQEELITYGPVTQSFFLQNMGIEVRLANLLKNTKPEEQKNLISGYKMLTDRHQMGERFKFLAFFPVGCGKSGSVWKIPHGFLLVVVLVADAVSGARLRRLSPFRLSLGGGTTVAIEGWGFSENQFSHSNATLGNRVVFENEDEAVECSVVSFLTTPTRVVCSAGKPLRATSDTEYRVRVYVDGVRASGELTALVSAKVTDSFPLSAYLGGNECQLYNSTSGEVLGQLRQDQLTCTVPGSAIGPANASVYVTELGASATLARDLLVDSQDQLYQFHVAPGVSSVSPPAGSSAGGSLLTIRGVGFHPHRNATSVRVGGAECKITNVSATTVTCIAPPRSLTTPAPGERGLLLELWEGQFAPDLRDRLRLSALTPHTDGYSSSVVTDLDFKIDAKMTFVAKLTGYFHAPHDGSFTLAAYVPTRYGTSWLAYVAADGDPDKAMPLPKWGSVELKADTPAYLEVVISGRKAGVRPTRVLMADHNGRFNSWQTSMATNERQSIILEPRVKHEVQRVTFSGQPGSVRLFFHGATSDPVDLSDDEEVRSAVLSLVGRKCQVQSEGKTKEIHFATGFEEGERLPLGMTAKVVNMLDAFCGSEHTRTQSRAAMDKALSTRAADSMEVIGFMSNKPRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NA13</accession>
    <name>A0A3R7NA13_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Putative ciliary dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_025489</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000989">
        <property type="protein sequence ID" value="ROT81354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7NA13"/>
    <dbReference type="OrthoDB" id="6373430at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000003">
        <property type="entry name" value="Dynein axonemal heavy chain 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000411">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000002">
        <property type="entry name" value="Dynein heavy chain 9, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF8">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="18">
        <location>
            <begin position="228"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="17">
        <location>
            <begin position="371"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="19">
        <location>
            <begin position="740"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="16">
        <location>
            <begin position="1198"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="20">
        <location>
            <begin position="1350"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="356"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="585"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="947"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT81354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1446" mass="164000" checksum="7BCEE5B124D15776" modified="2019-04-10" version="1">MVGRERARPRLMGMHGGQHRVAPALSPSAGSGTLSTFTNTQRSCPICNQGHARAFRPSREYKDVWLVCISAVVKCFLYRRQTPPALDAAAFLTDVGQPSIPHHLLVMARARATRSRLHRGGRHSILPSCNPIPYLLKCPRLPERRPGGPTATPMVPHLSPERLFTVAVAAPHRSLDLLLTVTTWRPAHLSRGHVQQKQFCLVLASSRCSKQGAAEPVPQAELCAAPVEVKSTGQQDTRDNCWRFFIDRVRKNLKMVLCFSPVGSALRVRARQFPAIISCTTIDWFHEWPQEALVSVSETFLGTLEYLPESLRGSVSKFMAHVHTSVNDMSRVYLTNDRRYNYTTPKTFLGFISLYTKLLSAKHQELQAKIERLQNGLQKLRTTSTQVDELKAKLAVQEVELQKKNDEADKLIRIVEAETAKVSKENEIANEEKRKVAIIEAEVAKRRKECEEDLVKAEPALVAAKEALNTLNKANLTELKSFGSPPSGVDRVTAAVMVLLAPNGKIPKDRSWKAAKVMMAKVDQFLDQLINYDKENIHPDIIKNITPYLEDNEFNPDFIRSNTAPSGLCSWVINIISYYEVYCDVEPKRRALEDANNELAAAQSRLTAIISKIKSLEEQLARLQAEFDKATAEKMRCEKEANSTAHTIALANRLVGGLSSEKIRWAEAVAQMHISEKTLPGDILLVAAFISYVGCFTKHYRRDLMDKMWLPLLQKLNPVIPITHNLDPIKLLTDDATIAGWNNEGLPSDRMSTENAIILTNSDRWPLIIDPQLQGIKWIKARYGEQLIVVRLDQKNSIDVLEAAITRGETVLIENLPESLDPVLDPLIGKNLIKRGRALKIGDREIEYNDTFQLILHTKLANPHYKPELQAQCTLINFTVTRDGLEDQLLAEVVKAERPDLEELKYNLTKQQNDFKIQLKHLEDDLLSRLSSAGGNFLGDTALVENLEHTKATAQEIQEKVAEARNTSAQIDEARELYRPAAARASLLYFILNDLHKINPIYQFSLKAFRVVFQQAIERSEANDEVRLRVNALIDTITYSVFLYTTRGLFEKDKLIFAAQMTFQVLASQGEVGAIELDLLLRFPIQPNVVSPIDFITNNNWGAIRSLSQVDEFRNLDRDLENSVKRWRMYCECEAPEKEKLPGEWKGKSDVQRLVIMRALRPDRMTHAMQLFIEERMGRKYVEGENIDFSQSYEESGPSTPIFFILSPGVDPLKDVERLGYSLGYTCENRRLHNVSLGQGQEKVAEEAIQIAAKEGHWVILQNIHLVRQWLPRLEKKLEIHADGAHQEYRVFMSAEPASKPENHILPQGILESAIKITNEPPRGMQANLHKALNNFTQETLEMCSKEAEFKSLLFSLCYFHACVAERRKFGSQGWNRPYPFNTGDLTISVNVLFNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFLHPDQVAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NTA5</accession>
    <name>A0A3R7NTA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002988">
        <property type="protein sequence ID" value="ROT66151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NTA5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="42137" checksum="A3FEE7A48A51DBF4" modified="2019-04-10" version="1">MIPPPLPSPPLSFPFPLLVCLTPPPFFFSLLFYSFLLFSFFFSFSSTSFSLLIFSSSPLLLSPPLLPSSSPLIPSRILLLLAPSPSSLILPPLLSFSSFSASSLFLFSSFPSLPFSYPPLLSFSSFQLPFPLPFLPPLSFPSLIPSSFFISSSPFQLPFPLPFLPSLSLPLLLFPSSFHLFFLLFSFLSLPFLPSFPFPFSYSLSFSSLLPPFLSSLSLLLFPSSFHLFFLLFFLPFPSPYSPLLFILLLLLPPLPSLIPLLFPSPFHLFFLLSSSLCLLLFPSSFPLSFSLFFLLFFLPFAFSYSLFFPSPFQSLLPPFFLPFAFSYSLFFFISFHLFFSFFSPHTQIFDNCFIEKENRTHKQKRIALTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NVS8</accession>
    <name>A0A3R7NVS8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative helicase senataxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_013824</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002723">
        <property type="protein sequence ID" value="ROT68045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7NVS8"/>
    <dbReference type="OrthoDB" id="2285229at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001147">
        <property type="term" value="F:transcription termination site sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="6">
        <location>
            <begin position="1676"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="7">
        <location>
            <begin position="1954"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="285"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="504"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="650"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="944"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1018"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="433"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="653"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="670"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="698"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="729"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="792"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="979"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1021"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1069"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1089"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1136"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1196"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1242"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1292"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1332"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT68045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2185" mass="245693" checksum="9136701F299F1C1E" modified="2019-04-10" version="1">MIAELRPGCQIGLGVPLNHATDEGIRNSQYVFLRLCEPEEQNETRGNMSSLNETVNFSPGQIGRRLSNSRPPGDTVPQTEKSEDAGKNASRTGTPQEGGIMSGTSATSFDPQAINVPKKTSYSHSGSGNDYVMPKLQPNSSDGFIPCIEPPTSATCTRPSLAAAANVPQSSGTTKPPALCVAQPEVSCSSNNVRSLPLLTRISSVKRKESLELFDNMDLKVQVNVDIPDQSEISNQDKHAASTGDEMRKSSHSISGLPLHAEETKQGPSSLSSEGQYSAPVVQSLETHRRQRQGSGAHSVSHIQQDSSMRSEGDACSRASPSFPVQHVHEIPDGISGSKPFSSSKEVSAKVSAENLGKSIVEDRATVMGSSSFYLNGKGASGFENQTPFQDQHVETKQLLQNVNNIKVQTPVLGPFETSCIKPTKEQTNSMEKTNEFDTYKDKKGEPKDCGQTDLITIDDEFSEGDDIIDLTQQDPVPDSSIEKKTKDGEQDLMACFVASLKEEEKGETANEGSAKRKRNTGEETVKSQSSTSVGFKDVKKARLSAPAVSNSNLMEDSESDSDSGVLKIQRNCKLKRRIVVSSDSETEMEKSKSLNEQTQQKEQFRIKTEINAWAKRNCQVAIEKLPSSLVEGAVSGKEIIDDKKIGLTVHIPPKDSRNRILTSRENKTSENTSNKVSSMGRKQNSKIDLPCNRFGLDDDDDDLPDLNNEDFKPIRGSVSSENVLVRRRSTEDDDKRKGKDPPKACRNGKGSFDSQCSDPPVKHHIGKKEPEPPSKRHKRQNSRDSQPSDAQETRDSQKVSRTDKNPKSASEVSLFKAGRNYKNSGESSDEASSKGATKCAVETSASVLSVAGSSLTNEDDDYIFCKPRPDTLVKIKKEVVQENVVNMKIKTEKIDKDQWHLNIKREPEEKGKECTEKKKFHDTGDDDDVLIMYSQVDEPIWLSSDEEDSTTSVNADVSFGPLPPSPELGIEELFATEDQQKEAETVDKAKGSAVTEIDIDEDDQWFPVLSQSFWDDDTEEIKKSSKMDEPVPGPSSTSSCAKQSDELEDDDKWLELSQGFMDDDADFEDKSSKDKDVTDSSLKYRSVTVEKSKNKDPRKSQLIDPKMPPARTKSDSLRKRGLGTSDTASWSSKRRGQEKAPDTDHRRLEESAEKHTKARTTKIITPPQKSYKKKGSSLRDNLAAKYNLQSYKSTVEQKKENHHLVPRPEDDKKKESSHRKSHLVTSEPRKEENISVQKKPSYKEGGDQAKSRSTVAAKVTSKNRSDKLIDINIFPSPEVPKPQLRKKYKIPKNDATKKADSSNDKKEGSSNVLDASTKRTPPAPEINTLENIERETRSTPTQKDSEKVTVTGDAKASSIMKDTEKGNVKAKKRVHFPSRLEDLEKVLYISPRKNAERLGALSVKAKEVLPKELLFLKYKIPNNYFDQFIYFVCRWNYDWLESYRVMQEKHANGKLKEVRPPPIVQNTTYPTLILYDSYNDYKEIFSTLMYYEVWEHVYQDWLQYRNTNMWLTAQIDVIQPLAVDREVNAPKFWVVKVITLITQEQSNRNYHPRQGSLVALKLHEGKRRVVILGYVDNIIKSRKRNVTKELDKMVPQGEVCLLLCMRVTKDTIQTVQLGKMIYVSNVSYIRPATRTWEGLCKLPQSPLCGDILKPSEEVFKCSQHPGEYIIHDMPLNSVQKKAVVEVGSKCTVDELVPKISLIHGPPGTGKTRTITALIAQITKSSRENKKPCRILLCAPSNAAVDELTLRLIKLKEIGLSLRLVRVGVKESISTELREYTLDSFVQRQVKIELSTPKNVSTRQEWERKRYMVKQAADALEKARKENRSKDEIKAMETRLNELVRGKTEFERSFHSQPNSQERFKLQQKWQEQFLLGAEVITVTLGGCVSGVMQEVLGKLPHAFTCCIIDEAGQCKETETWLPLLYGVRKLVLVGDHKQLPATVISQLAQNKNLKQSLFERFFYRYVIELQMDNVIHSLNVQYRMHPEIADWPCKHFYLNKLVTSPEIVMERTYGLRPYIVFDLKTSQEQKNQNNEFYNPAEASLIRILLEAIEPDIAQQKVAIITPYQCQKYKLEEKLAKFFGRINLVINTIDAFQGQERDVVILSFVRANPEANIGFLSQRQRLNVALTRARRSCYIVASLSSLAKNDDWKSLIQNAHDRNVVKTITQAEENDRAHIRKLVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3Q4</accession>
    <name>A0A3R7P3Q4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006886</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001876">
        <property type="protein sequence ID" value="ROT74601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3Q4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="752"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1047" mass="112138" checksum="4097E0A64EB9DDB6" modified="2019-04-10" version="1">MATTTSASLWPSRRGCRIIPYFTPFHSAEDFGYWTWAQLGTPGRLRRREGQAGREWSAGQPLSTSTPVTSSNNSTTTTVTSSNSTTTTPYHLHPVTSSNNSTTTTVTSSQSTPVTSSNNSTTSTPVTSSNNSTTSTPVTSSNNSTTLTPVTSSNNSTTTTTVTSSNSTITSSNSTTITSSNSITSSNSTTITSSNSTTITSSNSTTITSSNSTTIISSNGTTITSSNSTTIISSNSTTIISSNGTTITSSNSTTITSSNSTTVTSSNSTTHPVTSSNNSTTTTSVTSSNNSTTSTPVTSSNNSTTTTTVTSSNSTITSSNSTTITSSNSTSLLQQYHHHFQQYHITPPTVPPSLPPTVPPSLPPTVPPSPSNSTTIIPNGYPPSLPPTVPPSLPQQQSLPPTTVPPPPLSLPPTIVPPPPPSLPPTIVPPPPPSLPPNSTTTTPSLPPTIVPPPTVTSSTNSTPPPPSLPPTVPSPPPPLPPTVPSPPPSLPPTTVPPPLPSLPPTTVPPPPPSTPPNNSTPPRVTSSNSFHLHHRHFLQQPSLTRHSSKQLPPSFPPTTTQPIELSSNQYSTHHSPPDRSTTITSSKQYQHVHFLPTGYPPYHLRHFHLNNSSHHTYHIYIILLSNRYHLPPPSLSVHSNLRYHHHYVTSSNSSTITFLQQYHHSFPLNSYAPISLPPQYHHHLASIKYHHHSLQTVHHHFLPTSTSHQLPPNSTTHHFLQPVPPSFPPTVPPSLPPTTVTIHFLQQQYHHHFPPNSTVPTTSHSSLPPTIHSPPPYPTPPPSSAVPPHNSTTLHHRHPSPTIVPPPPSRVHNFLLVNLSSSSTAATFLPTVATLHHSRSIQTTNQFHHSPSLPPTRRVRAAIPTTVTSSPIVPPTNVEPRSLLQQQYHLHPSHSSLYHLHDTALFLFSICHPVTSSIVPPTTHIIVTSPTNSTKPYHPIVTSSNNMLTHPPPPSLPTHTCTSILRSSRHLPSFPISPTVIPPNKHYHTYTSSSMRHLPHTQRASAVLVPTTTISPSSTVPSPTNFVTFLQQCTVSHGDHYHLLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7A8</accession>
    <name>A0A3R7P7A8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C7M84_003878</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="22 23" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.</text>
    </comment>
    <comment type="function">
        <text evidence="19">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 19">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the BBP/SF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001519">
        <property type="protein sequence ID" value="ROT77470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7A8"/>
    <dbReference type="STRING" id="6689.A0A3R7P7A8"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22382">
        <property type="entry name" value="KH-I_SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000016">
        <property type="entry name" value="Putative splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.60.10:FF:000031">
        <property type="entry name" value="splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 19" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14 19" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="15 19" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 18" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 19" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="12" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9 19" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 17 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="21">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="374"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="481"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="531"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="531"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00055181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ROT77470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="561" mass="62265" checksum="F1811A383C3E3FF5" modified="2019-04-10" version="1">MSGANSTPLGRMNPAIGAGKKPTVTGGSSLLKPSYMSTLPNTTSNAAKRESESSYDSEREERKRRRKSRWQGDEKDKTFIPGMPTVLPSNMSKDQEEAYLLQLQIEELSRRLRSNDLGISPNPEDRSPSPEPIYNNEGKRLNTREYRTRKKLEDDRHTCIQRMMKINTDYKPPADYKPPVVKVSDKVMIPQEEHPDINFVGLLIGPRGNTLKAMEKDTGAKIIIRGKGSVKEGKVGRKDGGPMPGEDEPLHAYVTASNPESVKKAVDKIKEIIRQGVEVPEGQNDLRRMQLRELALLNGTLRENDGPRCSNCGSNAHKSWQCPDKPNVTNNVVCTSCGGTGHIARDCRQRRGPGAPATVDRQKIDEEYMSLMAELGEGPPPPQNTELTTKRPAAVPTTRSLFDRPQGAPRPLMAPPPRSEPQATPNNQFAANSQNQEWAATAAATKLDESSSTRSSRCSTGTSGSTWRSWWPTWRSTWRTTTWSSSSNEPLARSPSRTSSWSTRNGLPSTRTSATTSSCWTTTWLGLEWATTASGTSTPTSSRWPRRTWSPWTRNPYPQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDX4</accession>
    <name>A0A3R7PDX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000726">
        <property type="protein sequence ID" value="ROT83156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDX4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="649"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="740"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="808"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="851" mass="91219" checksum="FAEB3DC94D516A4E" modified="2019-04-10" version="1">MIRAVSWACIAGVLPLLQMPHPRISNLNDEAINELSPHTPTPHLAPPHTPNPLPTPQRPPTPLHNPLPPLTPNPLPPSHPQPLTPLTPTPCPPHPNALPPSHHPQPLAPLNIPNPCPPHTPTPLAPPQSQPLALTQHPTPCPLTTPNAFLTQTLAPPHIPNPLPHFRRPPHLPTPLPLLTIPNPFPSHAAPTPAPLTSPNCSMNYPLPVQPHTKPPTPFAPPHYLPPYDAYSPLTPNPLGPLLHTPQPLAPSHQPPTALPSRLTNHNSNLTLAQPLTPPTPLAPLQHHAQPLPPPRHPQPCAPGPHIPNLLAAYPQQTPQHPLPLSTPQPLAPSTPNPNCPISHPQRPLPSPHYPAKPHWPLSYIPNPLPAYSPHSFRPKLLLPPSHLQTLWPPPLHTQTPLAPSYNPNALAPPPSHPLAPPHNPQNPCPHQTPPPNPIAHTPPTLSPLHIPTPLPPHTAPTFRPPHTPATPCPTAHNIPPKPLAPSHPQPLPPLAHTPPTALPLTQQPPPLARPYTNTPTLPAQPLAPPHTPNPWPPSTDPQLSCPPLRTTPTPCPPSQYLPNPLPPPLTPNPCPLTPPTLAPPHTPQPPFPPFTPQPLAPPHTQNRPCPHTSNPPDLPPPRQLSALTLPTNHLNHLAPPHIPPLAPQYPQAPLVPFTQPLAPHKPQPPCPPPSQPPQPLPSTQYPRTPCPHSFSVPQPLSPHTPTPCPPSHHPNTPCHPFPPRTLPLTPPTPCPPLTQPLASPSTTQTPAPTAPPLPPSSHPTPCPPHTPNPCPSPQNPWPPHTTNPLAPPSHTTPCLTPNTLAPSHPPTPCPPSHPQPLPHPFPNPCPVRVRPNRILLSTCITSSRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEK1</accession>
    <name>A0A3R7PEK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Salivary glue protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003470">
        <property type="protein sequence ID" value="ROT63250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEK1"/>
    <dbReference type="STRING" id="6689.A0A3R7PEK1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="476" mass="51195" checksum="0BA7E4080E2602F2" modified="2019-04-10" version="1">MPKLHTPTYTGGLLACRPASSFSPPLIRHRRAATSSSSLKIKRRRNLAAPPTWRPAPPLLDQAPPTWRLAPPPLDQAPPTWRLAPPPRLGQPADRRLVQLLLPLDQTPPTWQPAPPPVDQAPTTWRSAPSPVNQAPPTWRPAPPPVDQAPPTCRLDPPPLDQVPTTWRPAPPPLDQVPTTWRPAPPPLDQAPPTLRSVPPPIDQAPTTWRPAAPPVDQAPPTWRLALPPVDQAPTTWRPAPPPVDQAPPTWRLAPPPFPFDACDGLATSSFPLISPAHLATRLPDKHADPALSRGISAAHSKGSWIKRQPTSPPSGAPDLALASSLRSSANEAWRPAPPPFLLPLDQAPPTWPTSSCSLDQVPPTWRPSSSSSINQAPPDLATRFLLPSSAATDLATSCPPSFDQAPADLATAPPTLRLQAPRLANSSPPFKISRRRLGDHSWRASLLPLRLADPTWDSSSSLIKAPSDLATVPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGQ9</accession>
    <name>A0A3R7PGQ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Solute carrier organic anion transporter family member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016045</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cell membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the organo anion transporter (TC 2.A.60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003010">
        <property type="protein sequence ID" value="ROT65972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGQ9"/>
    <dbReference type="OrthoDB" id="5062115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17336">
        <property type="entry name" value="MFS_SLCO_OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00805">
        <property type="entry name" value="oat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF76">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="501"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="540"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="785"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="10">
        <location>
            <begin position="605"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="825"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="55"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="825"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="850" mass="93117" checksum="D75EA663B78BDF3C" modified="2019-04-10" version="1">MKLATERIENIPWPDPPSKHTHFTPSLSSLTPPHPLLSPPTLLPSSFFHSSRPSPFTPRSPNPSPPLSTFFPILNPHPLPPFPSLNPLSSPTFSPAPPAHPSPPPPASTPAHLGSLLMGVRGNPLPSSLVGEVLRQGKWRRDRRSSSPLPRRSFCDGLRAKAFTMTQKKKFINGGLKPQIVPATEKSAATKAKEDEVLSLLTEGEAEDTICGLGSCTPSWLQSLARKECYLLVYCGIALIQGMFFTYTVSVISTIEKRFKLTSKESGAFLSGNDISQVILAMFLGYYGNCGHRPRWMGVGVMFAAVSCFMALLPHLLTCTGEDAENYSYYGAVIIFFVSQFFVGIAISVFFTIGVTYLDDNISKKTYPIYYAATLLLRILGPVLGYLMGGNFLSMWIDPTKRPNLTQRDPRWLGAWWLGFLVLGCVLVVLGNLLFLFPRKLPATLRREARAILKQAQKDSEEGENRGVEFFVKKAKAKKVERKPTLANLKKALKRIFTNKIWIANLFNTTTYILAVSGYWNFKPKYLENQFRKSAAEANYYTGVTSLTSVILGTGLGGAVMRWARPSPRFVTGYNIFVTLFVCAGFTSLMFIGCPKLEVIGPVDGSPLPGCSSNCGCSDRFSPMCSEDQTTLFYSPCYAGCTAIDTSVSPIVYSNCSCITNTTNPLSASHDASTGDKSAVQFGSGVSGYCPEPCDSFFYYLIIKIIISTVTHRRVGSSKAVSASCNALHKGLALGVVTVFISLFGLIPSPIMLGAVIDSACLVWDTSCGMTGNCWLYDSDAFRTILHLVPAVIVFISVFGDIVVFHYSRQLDLYGERDEEVHLEDLKDQTEESKPLNASKGDGGFEMGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGY9</accession>
    <name>A0A3R7PGY9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetyl-coenzyme A transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_010288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGY9"/>
    <dbReference type="STRING" id="6689.A0A3R7PGY9"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT71412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="50799" checksum="AEF439A59B06430C" modified="2019-04-10" version="1">MILQNRDVSYKDQATFSLSFWPFSIKLLWAPLVDSVYFQKMGRRKSWLVPAQYLIGFFMLILSSNINTLLGEGSAEAPNVTIITAVFFALNFLAATQDIAVDGWALTILSRENVGWASTCNSVGQTAGYFLGYVVFLALESRDFCVNYLGQADSLVTLPGFLYFWGIVFCVTTSLVWLLKHEKDESEVEVDEPDFGLIGTYQVLGRILKMKTLRDLIIVLLTCKIGFAAADSLTVLKLTENGVPKDRLALLSIPLTPVQVFLPLYISRYTAGPRPLTPFIRSYPVRLLFGLVFAGLVWATPLFKDENGVYPAHFYVIIIIVYLIHQVTVNCMFVGVMAFFARISDKSVGGTYMTLLNTFTNLGGNWPSWIALRYVSDLTWKSCSGVINVLSCNKEAEKQACEAEGGTCSVDVDGYYIESAVLVVFGFLWMKWGVPTIRRLQDLPMSAWAVSQRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-03-27" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PK91</accession>
    <name>A0A3R7PK91_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012489</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002583">
        <property type="protein sequence ID" value="ROT69295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PK91"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010475">
        <property type="entry name" value="AKH/RPCH_hormone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06377">
        <property type="entry name" value="Adipokin_hormo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="13445" checksum="2F358334C596CD15" modified="2019-04-10" version="1">MWEANPANSAGVGVVREAGRSLTCSHVPLRSPEVMMHKLQVLLLVVCVAVGPSLAQITFSRSWVPQGKRSGVAGALMAPEGPAHLGESCHGAYVDALMQVTAVVNNLIRTAHEAIAVDSLLLNPKASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKB6</accession>
    <name>A0A3R7PKB6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001869">
        <property type="protein sequence ID" value="ROT74635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKB6"/>
    <dbReference type="OrthoDB" id="6365068at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="229" mass="24411" checksum="4E309F76AB9E158B" modified="2019-04-10" version="1">MEGLNYVPEDMVFSFSDVTHVLAEKVKSTLQDPQPAESGRFIIPFFSGSGGCNDAFTGFGFLAFLLALLDLILELQDGNRRRRSVQEGLNMDPDILMTLALESGPETQGAAAACYSLYRAFLNAPRAREEAAPRGSCEGAEAAASGPLGKMIATVASANAASWLKKENATLYKGVEEAGAAGAAGGACGMRYSQCFGLPPLYRHPRVYTGDPLRDYRAPGSPSFRPKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMG2</accession>
    <name>A0A3R7PMG2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002316">
        <property type="protein sequence ID" value="ROT71272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMG2"/>
    <dbReference type="STRING" id="6689.A0A3R7PMG2"/>
    <dbReference type="OrthoDB" id="187712at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040067">
        <property type="entry name" value="WDR47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057749">
        <property type="entry name" value="WDR47_COR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19863">
        <property type="entry name" value="NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19863:SF11">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 47-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25602">
        <property type="entry name" value="WDR47_COR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="2">
        <location>
            <begin position="44"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="566" mass="64051" checksum="A0D4E2BD21FA643A" modified="2019-04-10" version="1">MPSAHLSLREEDVVRLALEFLQNRYLHISQLNVERETGIINGNHSDDALFLRQLILDGQWEDVLEFVQPLEAIDAFDTKKFHFIILKYKYFELLCIKAEAPNPSKEGAVDELVKVLNELEKYAPNKEAYSQLCLYLTLPRLHEHSDFRDWNPSAARVQCWTQVFPLVEKFLPAERRGGLAGDMEGVGMAKNDRLVQLIIKGLLYESCVEYCQSQATGDSSNSGTLKFPSLLSCTTFSDSDLSLLSWLQSIPPETFACPFEQKTLNVDVERLEKPSLEASWTEHLLVTPIKPRTFPHSAMPYNRPRARDIMSRSLNPNLDGLPFGLGSNRNSMALSTGDINMMSKSIASFHLTGKKTMNTSVDRLFDTENVFTSSSYGDLPTIIEKVGLPKPPPRRARSRSPDKRQSTDSLNKPAFSDKVEKDIREEKPGTPPALPPKSSPTPPQIPPPNHTPPNLPAPYQQPQHYPHPKQNVPLPPVPDGKPSLPPPQPPQQNQMPQQPPQPPFDSNCNANNDRETGELFSIYQRRQQMMGQQQQQMYDQYSNNNQMMMNMGTLHPPNMNMNRLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSC9</accession>
    <name>A0A3R7PSC9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mucin-19-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001025">
        <property type="protein sequence ID" value="ROT81079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSC9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="917"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="827"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="950" mass="98831" checksum="95CF3947BCE959FA" modified="2019-04-10" version="1">MQSHQWLPPCSLTSGSPYAVLPVAPPCSLPSGHHPGCPPSGSRCSLTSAPPHALTSGSPHAVSPETPPRQSHQWLPPCSLTSGSTRAVSPVALPVQSHQWLPPCSLTRDSPQAVSPVALSRQSPQWTPSRRSPPPRGSLRAVSPVAPPVQSHQWLPPCSLTSGSLRAISPVAPPVQSHKWLFPCSLTSGFLRAAPQWLPPCSLTSGSPLAVSPETPPRQSHQWLPPCSLTSGFLQWTATRMTPQWLPRAVSPVVLSRWRPQWTPPRRSPQWLPPCSLTSGSLQAVSPVAPSMQSHQWSPRAVSPVAPPVQSHQWLLPCSLTSGSLRAVSPVAPSVKSHQWLPLGSLTSVSLRTVSPVAPSVQSHQWLPLGSPTSGSLQAVSPVDTTQDVPPVAPPCSLTSGSPCSLTSGSPRAVSPETPPRQSHQWLSPGGLPSGSLRAVSPVAPTRQSHQWLHPGSLPSGHHPGCPPSGSSRAVSPVAPSVQSHQWLPPCSLASGSLRAVSPVAPPVQSHQWLPPCSLTCGSPVQSHQWLPPGSLTSGSLGAVSPVAPSRQSLQWTPRQSPQWLPPCSLTSGSPRAVSPETPPGSLTSGSSVQSHHLTSGSLQAVSPVAPPVQSHQWFPPCSLTRDSPQAVLPVALSRWSRQWTPPGCHPSGSPRAVSPVAPPVKSHQWLPRAVLTSGSPCAASPETPPGSLTSGSLQAVSPVDTTRMSPQWLPPCSLTSGSPQAVSPVAPPVQSPTAPPCAVFTSGSPRAVSPAVSQCLPPYSLTSGSLRAVSPVAPTRQSHQWLPPGGLPVDTTQDVPPVAPPVQSHQWLPRAVSPESQSLGTSGSPRRSPSGCAVSPVAPTRQSHQWLHPGSLPSGHHPGCPPVAPPVQSHSGSSCSLTSGSLRAVSPVAPSVQSHQWLPPWLPRAVSPVAPPCSLTSGSPQAVSPVALSVQSHQWLPRGSLSSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2I8</accession>
    <name>A0A3R7Q2I8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002881">
        <property type="protein sequence ID" value="ROT66832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018569734" evidence="1">
        <location>
            <begin position="27"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1291" mass="136296" checksum="2A8E93753D0C432E" modified="2019-04-10" version="1">MTRKKQLISLPLALLLSLLLPPPLTRINTSPLLPSWIPLLPSPFSLIRPPCLSPPSPFSLLSSPPFPAASSSSLPFPLPLSALPRLLPLGLPSFLWTSLPSPRPPFLPLGLPSSPRPAFLPTAAFLPSACLPSPRPAFLPLGLPSFPTACFPSPRRAFFQSACLPSPRPVFLPYGLPSFPTACLPSPRPAFFPSACLLPLGLPSSPRPTFLPLGLPSFPTACLPSPRPAFLNHGLPSSPRLLLPLGLPRHTFLPLGLPSFPSACLPSPLASFFHSACLPSPRPAFLPLGLPSFPSACLHSPRLASFPKLAFLPQGFPSSPRTPSLPHGLLSFPSACLPSPRAPFLAHGLLSFPSACFPSPRLASFPFGLPSFPLPSLPSACLLPHACLPSPRLAFLPLGLPPSVRPAFLPLGLPPSPRHAFLPLGLPSFPSACLPSPRPAFLPHGLPSFPTACYPFPRPAFPPLGLPSFPTACLPSPRPPFLPHGLPSFPSTCLPLPRLASFPSASLPSTQPAFLPLGLPFFPSACLLPLGLLPSPRPAFFPLCLPSFPSACFPSPRPAFLPQGLLSFPMACFPSPQRAFLPLGLPSFHSACLPSPRPAFLPHGLLSFPSACLPSPRLASFPSAYLPSARPAFLPHGLLSLPSACLPSLGLPSFLWTSLPSPRPLFLPLGLPSFSTACLPSPRPAFLPSPQPAFLPLGLPSSPSACLPCPWPAFLPHCLLSLPSTCLPSPRAAFLPHGLLSLPSAYLHSPRAAFLPLGLLSFPSDCLPSPRPSFLPLSLPSFPLAYLPSPRHAFLPLDLSSLPSACLPSFPRPSFLSSACYPSLGLPSFPSTCLPSFPSACLPSPRPLFLPFSLLSFPSACLPSPRPAFLPHGLLSFPTACFPSPRPAFLLHGLLSFPSACLPPHPSACLPSSGPAFPPLCLLSFPLGLPSSPSDSLPSPRPAFLPHGLPSFPSACLPSPRPAFLPLGLPSFPLAFLLSPRPTFLPLRMTSFPSTQPPCLPSGLLLPSACLPSPRPAFTPLGLPSLPYACLHSPRPALTPLGLPSLPSACLPSSRPAFLPLVLPSFPCLLRPRLPFPLPAFSACLPSPRLRPSPRPAFNPCPSPSSSPPSTRPAFHPLGLPSFPSNFLPSPRPAFLPLGLPFFPSACLHPPRPAFTPIGLPSFPTACLPSPRPAFLPLGLPSFPMPAFLPLGLPSFPTACLPSPRPAFLRPGFNSFGLPSPPPQLASFLWTSLPSPRPAFLPPTSACLPSPRPAFPVPSGLLPSLHHGLPILSPRPAFXWTLFRGDDTFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAA5</accession>
    <name>A0A3R7QAA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein spaetzle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_008914</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002121">
        <property type="protein sequence ID" value="ROT72693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAA5"/>
    <dbReference type="STRING" id="6689.A0A3R7QAA5"/>
    <dbReference type="OrthoDB" id="6359065at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005121">
        <property type="term" value="F:Toll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0021556">
        <property type="term" value="P:central nervous system formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032104">
        <property type="entry name" value="Spaetzle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052444">
        <property type="entry name" value="Spz/Toll_ligand-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23199:SF12">
        <property type="entry name" value="NEUROTROPHIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16077">
        <property type="entry name" value="Spaetzle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Spaetzle" evidence="5">
        <location>
            <begin position="284"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="42"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="458" mass="50078" checksum="F10D5D40FEF31242" modified="2019-04-10" version="1">MGRQVPRRVTELGEVGVRARITPLLTLRRGPCAVPCGVSFGSGKVVGSPSGSGQEIPLLTRSRPSAPRLFPPTPPHPPQAPSLNSTHHAHTPTSLPPHNTPTSPHNTQHAQCLPQPHAHTHIPPPAHDATRPRPSPHAHHAQRHILPHTRNTRPPPGGGAGVEGHFRSGPDILPRRPNQRHFSLPPVLAAGEATSRFQPMLAGELRSSDPPPRCAMRLGQDIDSPCLEDADYNDNLKEHIQFLLADPSVNSVVKDPLFKDLLNDNLVELRTRPLSTRVGASETPVCQSEETLIFPKRAKSSSNEWVFVLNQENVEQALRVEKCINEGTACEFESPLPPEIRTVCRQKYVYRRMLTVGSNKIQPEEVLMPSCCVCYRKSAGFDIGSRTRTPGTSNGGGQPISPAGSQPFVNTQPVGASFSQPLPANINFGNQPAPPFNHRTIRRRGFFGPGRGFFNNWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCZ9</accession>
    <name>A0A3R7QCZ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001843">
        <property type="protein sequence ID" value="ROT74821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCZ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="43460" checksum="AB89A8972ECFBAD7" modified="2019-04-10" version="1">MYSGVSFALASTLFIHFASTMYSGVSFALASTLFIHSASTMYSGVSFALHPFIHFAIHHVQWMSFASHPLYSSTLHPLCTVECRSPSHPLYSSTLHPLCTVECPFVASTLFIPLWHPLCTVEWSFAFLFIHFASTMYSECRSPRIHSIMHPLHSVVRPRIHSIHASTMYSGVSFASTLSFHFASTMYRECRSPRIHSVYPLCIHYVQWSVFRPRIHSIHPLCIHYVQWSVVRPRIHSILHHYVQWSVVRLASTIHFASTMYSGVSFVLASTLFIHFASTMYSGVSFALASTLFIHFASTMYSGVSFALAASTQSTVVSHPLYSSTLHPLCTVECFVRLASTLFIHFAYRVSNWYSGVSFALASTLFIHFASTMYSRSKRRDILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QD24</accession>
    <name>A0A3R7QD24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003389">
        <property type="protein sequence ID" value="ROT63723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QD24"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10068">
        <property type="entry name" value="BONE MARROW PROTEOGLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10068:SF14">
        <property type="entry name" value="CELL WALL ADHESIN EAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="880"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="975"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="886"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="976"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1061"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1160" mass="132853" checksum="1DFB2135159010B8" modified="2019-04-10" version="1">MRITIRSFTIGRIFTIGRSFTIGRIFTIGRIFTSAELHHRQNLHHRQNLLIGSRIFTIGRIFLHHRRNFTIGRNFTIAETSHRQNLASQNLPSAASAELHHRQNLHHRQKLHHRQNLHHRQKAEFTIGRIFTIGRIFIIGNLHHRRIFTMQNLHHRQKLHHRQNLHHRQNLHHRQNLHHRQNLHHRRIFTIGRSSPSAESSSSQNLHHRQNLHHQNLHHRRNFTIGRIFIIGRIFTIGRIFIIGRIFTIGRIFTSAETSPSQKLHHRQNSHRQNLHHRRSFTIGTSPSAESSSESSPSQNLHHRQNLHHRQNHHRQNLHHRQKLHHPQNLHHRQNLHHRQNLHHRQNLHHRLHQQNLHHRQKLHHRQKLHHRQNLHHRQNSPSAESSPSAESSPSAETSPSAGSHLPSAELHHRRIFSRNHRRQFTIGRIFTIGRIFTIGRIFTIGRIFITESSPSAESSPSAETIFTIGRSFTIAEDHRQKLHHRQIFTIGSIGRTSPSQNLHHRQNFTSASPSQKSESSPSAESSPSALHHRQKLHHRQKLHHRQNLHHRQNLIGRIFIAESSSSAESSSSAESSPSAESSSSAESSSSAESSPSAESSPSAEASPSAESSPSAESSHRQKTSPSAEIIIGRISPSQKSSSSQNLHHRQSFTIGRIFTHRQNLHHRQHRQNLHHRRIFGRIFIITESSPSAESSPSAESSPSQNFTIGRIHHRQNLHHRQNLHHRRIFTIAESSPSQKLHHRRIFTIAASAESSPSQNHHRQNLSQNLHIGRNFIIAESSHPAESFTIGRQKSSPRQLHHPRIFTIAESSPSAESSPSGIGRIFHHPAESSPIGRIFIIGRIFTIGRNFTIAESSSQNLHHRRKLHHRQIFTIGRNLHHRQEAESSPSAESSSSAESSPSAESSPSAEASSQKFTESSSAETSPSQNLHSSANFINQQNLIIGRIFTIGRSFHIGQKLHHRRIFTIAETHHRQNLPSSADSSIFHRQTSPSAEASPSAEASPSAESSPSAETSPRQKLHHRQKSFIIAESSIIGRIFTIGRSFTIAEASPSQKSSPSQKLHPSQNHHRQNLHHQQIFISAKNLHHRQKQQKLSPSQNFIHRQRTFTIGQNSRHIFIAQNLHHRRIFTHRHQSQKLHHRQTSSQNLPIGAETFTIAESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QD30</accession>
    <name>A0A3R7QD30_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_018362</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003387">
        <property type="protein sequence ID" value="ROT63737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QD30"/>
    <dbReference type="STRING" id="6689.A0A3R7QD30"/>
    <dbReference type="OrthoDB" id="6376512at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032870">
        <property type="term" value="P:cellular response to hormone stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241:SF170">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241">
        <property type="entry name" value="NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="9">
        <location>
            <begin position="110"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="43477" checksum="2AA1747C10B8990D" modified="2019-04-10" version="1">MVGAPGLDGGLLSGADGAVMGGDTVEDEVDLGSIPLLETPPGEQPPPSPRLLGYSGAYGANGGYGPGYGNGYPAYGGGELVMLAGGAHVGVESLAQAAVILVIGVAIIISNIIVLATFITMPGPKDVIMYYLMSLGVSDLVAGVVVVPLSVYPALVQRWVYGDAVCGLAGYLETTLWFAQLCTFMWISVDRYLAIRKPLRYETVQTKTRCQCWVVFTWITSMMLCCPPLLGFNNSSHWDSEAFVCWLDWGSMIAYAFTLVPMVLGPTLITLFYTYGYIFNTMRRLKTCVVGQDKEFITALTSNLANPDHAMSFVLVLTFWLSWGPCVGVRTYEYLTGHHIDVRFLHFAVFWLGALNSCWKSIIYIAMSPKFRRGLKLFCLSLCCQRKARNAELIMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QDQ0</accession>
    <name>A0A3R7QDQ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003288">
        <property type="protein sequence ID" value="ROT64248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QDQ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="44613" checksum="8537ADD12AA911F0" modified="2019-04-10" version="1">MVSPLRPSPRICTIAHLSNRHVNPAFRSFPVASAGEATECAVSSFRHCSFSPSSSHPNLLLPLSLPSPCPPSPSPSQSFSPSPQPPPLSSPNLSPSTCPSLHLPLPPSQTFPPSPPNPLFHPLSNFSPSLPLLPLPNPSFPHPNLLLYPLPISLPHPVPPFPSSPSQSFSASPQPPPLSSPNLSPSTCPSLPLPPPPSQTFPPSPPTLSSILSQFLSLPSLPPPNPSPSPTLILLLSLTILLPPPNPSLPHPRPPPTSSPNLSPSPCSSLPLLPLPILLSLTPTFSSILSQSLSLNLSLLPLPLPPPNLPSLTPNPLFHPLQFLSLPPLLPLPILLSLIPDLLLHPLPISLPHPVPPFPSSPSQSFSPSPQPPPLSSPNLSPSPCPSLPLPPILLSLTPTSSSILSLTLSLPLPLTILSHLFLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QG77</accession>
    <name>A0A3R7QG77_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Primosome subunit DnaD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001461">
        <property type="protein sequence ID" value="ROT77892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="961"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1187"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="899"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1610" mass="177557" checksum="DF0C3A0C24C2DEAD" modified="2019-04-10" version="1">MSADLKSISSRCQAISSQSQANFEPMSESQKKPMSGRSQVNLKPISSRCQADLKSISSRCQADLKISSQFRADVRPISTNFEPMSGRSQVNLKPMSGRFKSISSQFRADIRPISSQFRSRCQADLKTNFEPMSGRSQLNLKPMSGRSQANFEPMSGRSQQFRADVRPISTQSQADVRPISSQSQANFEPMSGRADLKPISSRCQADLNSISSLNLNFEPMSVDVRPISSQSQANFEPMSGRSQVNLKPMSAVNLKPISSRCQADLNSSRCQADLNSISSRCQADLKSISSQFRADSGREPMSGRSQVNLKPMSGRSQVNLKPISSRCRSQVNLKPMSGPISSQSQANFEPMSGRSQANFEPMSGRSQLNLKPMSDLDLKPIRADVRPISQSQPISSRSSQSMSGRSQVNLKPISSRSQVSRCQSQANFEPMSGRSQPISSRVRPISSQFRADVRADLKPIRADVSRSQSNFEPIRPISSQFRADVRRSQLNSADVRPISTQSQANFRAEIRPISSQFRADVRRSQANFEPMSAGRFRPISSQSQANSSRCQADLNSMSISSQFRADVRPISISSRCQADLNSISSRFQADLNSISADVNQAISSRCQSQANFEPMSGRSQLNLKPIQADLKADVRPISSQFRADVRPISSQFRADVDLKPISSRCQADLKPISSRCQAISSQSRCQAISSISSRSSQFRADVNQVNLDVRPISIRADIRPQANFRADVRPSQLNLKPMSGHLKSISSQFRAVRPISSQSQPMSGRSQVNLKPMSGRSQLNLKQFRAVRPISSHFRADVRRSQLNLKPMSGRSQVNLKPISSRCQADLKPISSRCQADLKSISSQFRADVRPISSRCQADLKSISDVRPISSQGPISISSQFRADVSRSQRCQSQSISSNFEPMSRSQVEPMSGRSQLNLKPKPMSGDLKPISSRCQADLKSISSRCQADLNSISRAVRPISSQFEPMSGRSQLNLKPMSGRSQVNLKFRADVRPISSQSQADVRPISSADLKSISSQFRADVRPISQSQADVRPISSQSPSRCQADLKSIQANFEPMSGRSQLNLKPISSRCQADLKSISSRCQADLKSISSKADSGRSQANSSRCQADLNSNLKPMSGRSRQFQANFEPMSGRSQLNLKPMSGRSQDLKADVNLKSISSRCQSQQFRADVRPISNLKPISSRCQADLKPKPMSGRSQLNLKPMSGRSQVNLKPISSRCQADLKSIPMSADLKSISSRCQADLKSISSRCQADLKSNLKSISSQFRADVRPISSQSQANFEPNLNSISTQFRAGSAEADLNSISINFEPISSQSQANFEPMSGRSQVNLKPMSAESEISSQFRADVRPISSQSQANFEPMSGRSQVNLNSICLKSISSQFRADVRPSDLKISRFRADVRRSQVNFKPSADLKPISSRCQVNLKPISSDESQVNLKPQADVSSQFRSQAISSRCRPISSQFQANFEPISSQSQANFEPMSGRSQSRSQVNLKPISSRCQADLKSISSRCQADFDLKSISSNFLQADVRPISSQSQANFESQANFEPMWISVSSSADLNLNFERSSQANFDGRSQVNPSQFRADVVLVNLKSNLKPISSQFFNLISSRSRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJK9</accession>
    <name>A0A3R7QJK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative phosphofurin acidic cluster sorting protein 2 isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_012214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PACS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002549">
        <property type="protein sequence ID" value="ROT69575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QJK9"/>
    <dbReference type="OrthoDB" id="28829at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019381">
        <property type="entry name" value="PACS1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057541">
        <property type="entry name" value="PACS1/2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13280:SF17">
        <property type="entry name" value="KRUEPPEL TARGET AT 95D, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13280">
        <property type="entry name" value="PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25332">
        <property type="entry name" value="C2_PACS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10254">
        <property type="entry name" value="Pacs-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphofurin acidic cluster sorting protein 1/2 N-terminal C2" evidence="5">
        <location>
            <begin position="639"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofurin acidic cluster sorting protein 1/2 C-terminal" evidence="4">
        <location>
            <begin position="973"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="523"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="714"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="840"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1197"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="524"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="563"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="598"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="742"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="871"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="926"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="958"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1207"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1224"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT69575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1386" mass="156167" checksum="808A5B56E6F52639" modified="2019-04-10" version="1">MPLFHAFRCRLMPLFHAFRLSPYALVPRVPLSPYALVPRVPLSPYAPVHAFPLSLMPLFHAFRCRLVPLFHAFRCRLCALVPRVPLSPCALFPRVPLCLVPLFHAFRCRLMPCSTRSVVALCPCSHAFRCRLMPLFLRCRAFRVPLSPLMPLFHAFRCRLMPLFHAFRCRLMPLFHAFRCCLVPLFHAFRVALLPLFHAFRCRLMPLFHAFRCRLALFHAFRCRLMPLFHAFRCRLMPLFHAFRCRLVPLFHAFRCRLMPLFPRVPSPCAFAFRLMPCSTRSVVAPLFTRSALVPLFHAFRCRLMPLHAFRCRLMPLFHAFRCRLVPLFHAFRCRLMPLFHAFRCRLVPCSTRSVVAPYASVLPLVPRVPLSPPLFHAFRCRLVPLFHAFRCRPRPRSDPGTARERGGPRAALPEALEGFLHARSPLAPPRPSAGTEHALLIASAVLGVAENALGSRTYERDRQTQASFFLGCILQGLECDSDFSGAARRPLFSLRRGGLECARQHFRGFFASGLAFHLGGGTPHLHSTHTPPHTPTHSPIHPYHPTRAPLPTHTPLTHPTIHPLPPTHPLPTHTPPTRPTHPLPPTHPHPPLPPTHTHPTYPTRAPLTPTPPHPPPHPPCTPTPPAPKRHLPDPLLLPLQYPHFLKREGNTLQIMLQRRKKYKHRTILGFKTLAVGVINMSQVLQRPVDRELELYSEGKEKGVSLAKVTMVSLSSQPVDTDEPPERAKSFMADNPDLVEVYSDDDEDYSSQDEGSDSEPILEDGSRRTHHHLRSNTRSKSLPPNARQRNLKQRFIALLKRFKVPEALQAFDQDQELDPRTGGEVDEAEIEDLFDELEDLSDSGPEVDTISITSTPKPSLRPYFSSSRSLLNEDKVGADRLSDESSKRADSDHMENWTDQEHSDPQCLASSPPREDKNKSNKNKLFNRDRSNMSLKERRSVSSTGGSTPRQEKMVVERSNSSANVDSSPRKVLLEQLARVLPVEDVQLPDHVVLVNTGESHGPLLSAHLTEHGHRVITTMSMADVKATVSHLVNKLQKFCNSNAKAPGPMKVVVVGSDTYISCVLRPYVDQFSSKPPDFQNHVRFLIIPLGVNSLAKYLGSVDSVYGAAFVSESWREVVERWEKPDVQEVVNRIHRYLTQAQHTLHLPIAEAMLTYKEKSGDDESTQAFVPFIMDVRLGSGDVTSSSVDLDEPLSTPTAIILPGSPPAASTPTTGLSIDKTRDNTTPPSSPNINSSHLANYKSLSESGGQEALDLQVDYWLVRSSGREDKEKEKEKEKARVEGGKYTLKTSFRTLQVARLAPLGVTPPVDPYSFQHLTLSYATKEKKQRIVDGVSRLLASAKNQPFKVNIDSAEWTNVKFFQLSSQWQTQIKTFPISLFSLQDSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QL07</accession>
    <name>A0A3R7QL07_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_024613</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000857">
        <property type="protein sequence ID" value="ROT82218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QL07"/>
    <dbReference type="OrthoDB" id="7852576at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="560"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT82218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="670" mass="76086" checksum="B6F1D743A5BC4A49" modified="2019-04-10" version="1">MAKTLGWIEKYEFEIALSTQHRQAPTNEHSVILQKILLNLQNTIQMMLAEQQRPLTGSFTSEVPPSEGKELTSYHPSTSDEIMCYAPDRVYRSDKKADSEHIIASGQEPEDKVTECLPQQLPTTKEAEAANVLMNLSGKAADRVGHTRLEGCTILHQEIISSDATKPTLYVVPSGISNSNVKREYPVCDEVPQINEKDLLPLATQVLCQFCSQQCEDLVELHEHVLAMHNMCETEPPFMTSYKKLKNQNQDEDVESTSPGEGRRHKESKNKNYEQESHSLDELLVPVTSSGGILRHESEKRKFIDDKKAKKKPRSRKGNQNAEGKSASLELCNKISHTEGQDSYSKNVWNKSNDSRQELIHDINMSVIDNIPKQYSPLTTGQVHLEDKEKSVQMHQPTEMPVSQVKGDALAIAIESSKIRVIEAKVTIFVCLKCSSCYTNAQEFRIHVCSRIQPVIERCPDGSVVLVKHVNTEENQAQLSEEEVWYFPEFLIRQQKGDKKQTGDLEIVDTLSGHRLQLYTAYQPSYLSEQLISFRCPTCEKDSDSLGKFFDHLTKGPCMFRCPDCSLVYVTQDKLQKHRSSLHPTLEDRTCPNCHEVFEKRHQRNKHVKTQCSQLHICDTCGSVLKNEYNLRVHMLSHQSGAHSPYDAPLRYKTTRLSTVQCQVLHEATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLZ2</accession>
    <name>A0A3R7QLZ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000705">
        <property type="protein sequence ID" value="ROT83283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLZ2"/>
    <dbReference type="OrthoDB" id="6378618at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="603"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="834" mass="92948" checksum="506F93F62C3AEA09" modified="2019-04-10" version="1">MLSQSRMIPGQTPLDYYQQVEMAVFQGVRDYPHEIGDAEGLIRRTFKAGLPERLQRQLSLHTFSSARAMAERVQCAWNDWTGLRMSLPLATQVSRHCGGQASQPCLTSLVFYLYLPTYYTSLTAESVPGLDFYSDNLFLFRLLRQLRQVPQAIPTTLTMRGVSRVLLGNDNFRQCALRSGAPIIGPRHFLPAEETFHVSPQVVSPKGRPTIQVRVNSKVLTAFVDTAPVHVVQTEFIEPKSGQFVSAAVARGLPESRAILVEGTNPKFIVPRSISAVQGRRTSVWVVNPDAKQRKLTQGTCIGFAEQVGAEQLVDVSAEGNVTGKEPRVKEDTVTHPSSTGHAGRDFSPEAAEFSQPKFTDATTQVHSLAEIDADELAPRSCKVWPADEQVAECPSDTSDDDIELCINVVESSDSPSKQVDLGHLDSVQQEELGKVLNKFPRLFSGDKATIDEALAVNENHSVNSDTPVNLATLASAVLREYQLKEDLWKEIIEFLEGKKLPRRALPASLHEFELDDGVLYHLKSLPIELSGRCVFLIHCSRKPYILLMTILLQLTLVLYVHTTICKIATSFQTCSGYANGTCSTVQLVSTGKVHVNVPRCSVVHHPVAHWSLCPQISWISELPWVAIDMFCQVDHHSRYLQLVPLRNKTAETVLRGFYDHFITLFGPPRQIMTDNGGEFANEQWQEVCRQLEIRCSFTIAYHPSSNGLVERTNRVVKDALAMLVADKPGRWPLYLTSVRGLTNQVTTDTNLRVQQLAKARQLAIAASLRSREANAQAHNRKVRSTWQPEEGALVLRRDFTGGALQDRWQGPCRVIKQIGPVVFEVKDLQPLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMV2</accession>
    <name>A0A3R7QMV2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 11</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MED11</name>
        <name evidence="12" type="ORF">C7M84_022626</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000585">
        <property type="protein sequence ID" value="ROT84176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMV2"/>
    <dbReference type="STRING" id="6689.A0A3R7QMV2"/>
    <dbReference type="OrthoDB" id="5418434at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3490:FF:000001">
        <property type="entry name" value="Mediator of RNA polymerase II transcription subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019404">
        <property type="entry name" value="Mediator_Med11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22890">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10280">
        <property type="entry name" value="Med11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="89"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT84176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="23414" checksum="42EA8E19AC77D68E" modified="2019-04-10" version="1">MAMASPMDRLQVLDNIEKDIATVLQSAGQALNELSKDKPANKQVEAHVNQFRQTLTNVETELAKQINYLTQVSTGQAHEGSSYNSQKTLQMAMHRLDHAKTRVNELEATKTKHMQLMQQHQMQRQQGMQQPPPSMSVREHALWVTLVYTPFTFLLIPHPPVYSLSNPSPNSMPSLLLTSSPNFLLPFSTSPPFTLITLPFSLSLFFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNG5</accession>
    <name>A0A3R7QNG5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000506">
        <property type="protein sequence ID" value="ROT84711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNG5"/>
    <dbReference type="STRING" id="6689.A0A3R7QNG5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="745"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="774"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="797" mass="84155" checksum="EF716AD198BEDADE" modified="2019-04-10" version="1" fragment="single">AQESSLNNLRTAPPPPSPPIPLSPPSPPLPPSPPPLIPPPPPLPWSPPFLTLPPIPFPFPPHSTSSPPPWSPLPTPPLPHPLPLPPPFHLSPSPLVLSSLHPPLPRPLSLLIPPPSSPPLVPPPTSHPPSPRLSPSPPHSTSLPPFPLPSPFPPLSTHSTSPPSPSPDPNPTLYPPHPPFSPLLSPSFHLLPPSHPLPPSPSLSLPLPPPSFPPPPSPSPGPPPFPPLPPTIPFPYPPFHLLPLPGPPPSTPSPPPSLSSPHSNHPPPPLVPPPSHPSPPRLSPSPSTPLPPSLVLPPSLPPSPSPPSPPSPSPDPNPTSSLPPPFPLPLPPHSTSSPPPLVLPPSHSLPPSHSLSLPLSLPSFHLAPLVPPPSFHLPLSLPSPPSFHLPPPPDTMGIGQKRFVFFGIKIRERNRPSCHGNRRRPSRGGRADSHAPPSPCLCLFPLPLPPPPPSLPLPFPLTHPAALSLFSLLSPPFTSYLFLPSPLSLFSPLFPPSPFPLTILILASLPYLHPLPPSLPLPLFLTVVPPSPSLPPPPLTILFVSPSGPPPPLPPSSPLLFITLSPTPLSPLSHLFSSLPPLTSTLPASLPLSLFSTVVSPTHPTSSPLPSHYSHPCPPTPPSLPLTILILPLTPPFPLLSTILTVVPLPPLPPLSLFSTLVPFTPYLLLPPSHYSHCCHPYTPSLPLSLFSLLSPCTPLSTPPPSPSLPSLFYYSPPCPLLLLPPPLTIPHPCPLTSTSPPLSLFSPLSLHTILTLVLSLSCLLFITTCVSSFCLFVLFFFLLSLFFPPSLFLNSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QT76</accession>
    <name>A0A3R7QT76_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamate gated chloride channel alpha 3A subunit variant</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004102</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001546">
        <property type="protein sequence ID" value="ROT77245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QT76"/>
    <dbReference type="STRING" id="6689.A0A3R7QT76"/>
    <dbReference type="OrthoDB" id="6378956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="9">
        <location>
            <begin position="136"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT77245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="33051" checksum="7B6BCE98723F504E" modified="2019-04-10" version="1">MRLREVLTVARSSSPEEDDPSRIAHDEIYEGSKNPLRLTQKINAPFSCAMDLQNFPFDTQHCKLLIRITSAREEFLRWSDLTVQYLGEVRVLMEETANRIRVGDMTIQRREEDEYSVAVVGMIFYRRYWYYLTSAYLPTIMLMLISYASLFCKRDNRDLRVMMAITTLLVLYALYQQISDGLPRTSYTKAVDVWCFFAITFIFSQVISTWPCAIDVEMSWPRRVRASPRVKEIDLANKPRRRFPALVVARIVYALLLVFFCLIYWAVVLVDKNRGEMEHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QY56</accession>
    <name>A0A3R7QY56_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor E2F4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_023973</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the E2F/DP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000767">
        <property type="protein sequence ID" value="ROT82855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QY56"/>
    <dbReference type="STRING" id="6689.A0A3R7QY56"/>
    <dbReference type="OrthoDB" id="1743261at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14660">
        <property type="entry name" value="E2F_DD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015633">
        <property type="entry name" value="E2F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037241">
        <property type="entry name" value="E2F-DP_heterodim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032198">
        <property type="entry name" value="E2F_CC-MB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081:SF18">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16421">
        <property type="entry name" value="E2F_CC-MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144074">
        <property type="entry name" value="E2F-DP heterodimerization region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F transcription factor CC-MB" evidence="6">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="68"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT82855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="282" mass="30733" checksum="D07D92223E6C67E6" modified="2019-04-10" version="1">MAYVNHEDICNCFQGDTLLAIQAPSGTQLEVPIPQMVNGDKKYQIHLKSESGPIYVLLVNQEQEHTPPLVVQVPPPTGVMKQETEPRGIKRSSSPPCSQAPFTRPRSTPQKGTTAHTPPTRSPSHPEGVDSVETASVSRRVPRKASAGVSSVTEALAPRRARKRQEQAAAAAAAAISSTQPAEVVKHEKVEDMLPMPVANIKQELREDSFVNTNISHTTDTMLSTMGEGLVEELISAEMFAPLLRLSPPPSERDYMFNLDETEGVCDFFDVPVLSSLESDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQB9</accession>
    <name>A0A3R7SQB9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA replication ATP-dependent helicase/nuclease DNA2</fullName>
            <ecNumber evidence="5">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="24">DNA replication ATP-dependent helicase-like homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">C7M84_011059</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="31">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="31 32" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="31">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002402">
        <property type="protein sequence ID" value="ROT70644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQB9"/>
    <dbReference type="STRING" id="6689.A0A3R7SQB9"/>
    <dbReference type="OrthoDB" id="306218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18041">
        <property type="entry name" value="DEXXQc_DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22318">
        <property type="entry name" value="DNA2_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000721">
        <property type="entry name" value="DNA replication ATP-dependent helicase/nuclease DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051827">
        <property type="entry name" value="Cas4_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026851">
        <property type="entry name" value="Dna2/JHS1_DEXXQ-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048459">
        <property type="entry name" value="DNA2_Rift"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36531">
        <property type="entry name" value="CRISPR-ASSOCIATED EXONUCLEASE CAS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36531:SF6">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21123">
        <property type="entry name" value="Dna2_Rift"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="21" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="19" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="15 31" id="KW-0347">Helicase</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0408">Iron</keyword>
    <keyword evidence="18" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="23" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="32" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="27">
        <location>
            <begin position="474"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2 rift barrel" evidence="30">
        <location>
            <begin position="830"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="28">
        <location>
            <begin position="988"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="28">
        <location>
            <begin position="1090"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="29">
        <location>
            <begin position="1165"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="80"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="26">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00032548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="Pfam" id="PF21123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="ROT70644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1234" mass="136805" checksum="8AA4453D96793A55" modified="2019-04-10" version="1">MGKLKAKISPDKNQKKISSFFSAPSLFTTVQHGSSSAGARSKLSGIGSNKEKDKLLTTKSNGATTVLQKKSAFGNGACSSGFGKGKKTDLAEEISDSSEVWSDSDPEVIESTPEIKKSSAGLLKSSKISASPDFIPSTPQLNITKLSDTKSFCSGLSGKLSSIVSSSSHTATKSSTLSVSNVMRPTSLAMKNKSKLSRLSRKIHEMKSNSVNKSEQQILKDSHFLSDQIAGKLKRPAATGMGISPDPKRTNVPDIVIPEEKEDCKSNLLSKFEDQNSYTSDAESDGSVSILLPDCKKENKENILNKGESSNGDDVLRSKMNNGDLNSFIKEDSCKSPVKSEKTNSIKAASDSDVLDHKDISEVLEASQGFMADIAFDDVEPKKQEPSVIPETQEDSMDHLFDDDLAVDFEKMSPFKQEVQQVPPVENKAIKKLLFEGLGEESFSMKGGFGRHVVSAVERNTYKGEVLLRLISVQDKSNKTCTLGGFWSQSMVSEGDIVHILYTEASEDGHFTVNNTQGLIVINPDFLISGTSVVSGVFCRRKAVLNERFRGLDPGNQLMLIGSLVHELFQEVVKKKIKSREQLEHLVRELMSQPKMLQEMYGLGVSEAHIYEEMNNFIPHINTWSQRYLATENYKFGVKGKIDMTVKTNQRGITKVVPLELKTGRSSFSAEHKGQVTLYSMMSADRRHDPRAGLLLYLRDGAMEEVPAGEREKRGLIQLRNEMIYYLTAKPMKQEDGELKLPSLPEPIDSERACTKCAHLLTCSVYQKSIEEIVPEPPHSMSVLVPKTTSHLSQAHLDYFRHWCLLLHLEIAEGKRDSAIRALWCQDPKRREDGGDCLSMLILERGVPVNEPEPGIFLHSFVRSPKYSTMPSLSAVGLQASDNIVVSSETEIALSLGVIKVVHEQSVQVVLDRDLTAYPTWREKLFCVDRCEYQNTMSINFTNLARLLSDTPQAAILRELIVDRKLPTFKKGLGEDVVKKGKKILQMLNKTQQRAVLKTLMAEDYSLLKGFPGTGKTSTIVRLVQLMVTLGYSILLTSYTHSAVDNILLKLKDLEVDFLRLGRIARIHSDILTHADETLARKFKDVASLSQFYFSKKVIATTCLGLNHVIFTKRTFDFCVIDEACQVLQVAALGPLFHAKRFVLVGDPKQLPAVVQSKQARNLGMSESLFKLLDSQGATSSLTDQYRMNGPIMRIPNGLMYDGQLKCASEELAVATVHLPHYENRQSDFRAKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUX0</accession>
    <name>A0A3R7SUX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase SH3RF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001676">
        <property type="protein sequence ID" value="ROT76289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SUX0"/>
    <dbReference type="OrthoDB" id="252722at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051435">
        <property type="entry name" value="RING_finger_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791:SF34">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="3"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="45314" checksum="C10E352E151774B3" modified="2019-04-10" version="1">MECKVCLEPYDQAERRPRALPCGHSFCSQCIGSIFRQGALSCPKCRARHAAPDASQFPFAYELEEMIALLMQRNLSVSAPPYEEGCDSPAWEAKEQQKSSLLNSISDCEEMLSQLHSYDASLDDSLARHQELVNRLADIIEQHKRAQTRLENNKEMALEWIRECQQLCPDVGTAATSSRTRAATARALEAFAQGMDAASAPVPPKSHLPEAERRFSILGILKEATALAPTTTPITQLMEGGQLVGVQYEQGRPRYARITMDKETVCLHHLEDESPPTHAYTIPYRKFVLMCTGHAGPSYARTRLLNLVDSTSKDELVGGDYECNDGSGGAPILSGIVSNKVMLPCAEGLVSGKWHSSEASSTKFGITTKKHEGYVWVRVFGKVESGLEVVRAAAEVGDVGLVSVVDCGVVVMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SV34</accession>
    <name>A0A3R7SV34_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane protein 134</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_004880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM134/TMEM230 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001647">
        <property type="protein sequence ID" value="ROT76537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SV34"/>
    <dbReference type="STRING" id="6689.A0A3R7SV34"/>
    <dbReference type="OrthoDB" id="10048380at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039714">
        <property type="entry name" value="TMEM134"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008590">
        <property type="entry name" value="TMEM_230/134"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13558">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13558:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05915">
        <property type="entry name" value="TMEM_230_134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="19880" checksum="288EBA6222D43B4A" modified="2019-04-10" version="1">MAGKQSRKNPKFTIEDAFEEDADDAIRLYGATNERSPFRPKDRDGIMGVDDVSMNMDDSVLGSKGFLTVPDVDAISRDSDSLIPGDASSFSESPRWWFLHPKVREKWTLVAGAFTLLILGLTLLVTGIVVQVIPIEGVSGIVFIITGLICFIPGAYHIVYVIFAVSGRRGYDFYNLPLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWT3</accession>
    <name>A0A3R7SWT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001302">
        <property type="protein sequence ID" value="ROT79019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWT3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="494" mass="55045" checksum="704FE254E9FB8CFE" modified="2019-04-10" version="1">MALRPTGRHIRHLCLSLLYKPPSPLPARATEGLGFSEYQPYNLKLCQRRASRQRTVKYEFIPCRQNLDKRSTLPPRGARQRALSLSHVASHWPLLCARRPQPPQSYAQSKRLAPEDDLPDVPTKARFPSLRLVISLACKHRRKSGSRVPPPPPVREPQAKRPSPRPRLSDSASRLTVTSGMQVRSRLHDDLHHDAVLRCLGPWTCTDKRRFDIAALRSDNEDSVTLSDRCKHAASVCGAVCIVASAGLRNSSPYLAAHRASLPKEGPRARRNARRAPFIGSLPKPIKRPVKTTADSKHKIMIINPSHKPITGALYILPHFPPLPSLPRALSSSLPYFYFCLNPFLPLYFFFSPPLFFPHPSTLSPILPPLSLFLPPFSLSFLPFLPASPRTSVFKFTILRKNATLTDKLASGTLPPPPFGGGGFWPTCRGPSKKKKPPPPPYTPPRFVPAARVCRMVERVVEVVGRASGGIWSYCHIQATLMDFSIARPKLGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0M9</accession>
    <name>A0A3R7T0M9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0M9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="630"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="687"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="799" mass="90234" checksum="6A9CC622F1219393" modified="2019-04-10" version="1">MLPSAAEGDPLTNPFSVLMSSAATARFVCNVPATRREKMGHHHSSPPHHISPQLITPSQLLSPHPIPSPQLATTPSSHTNHTNTTITTLHQPITTLTHQSLTHFNHHPPQLFTTNHTTLHHQSHPTLHHPITHTSPTNHTTLHHQQHPHFTTNHSTLHHQSHHTFTTNSTLTLQPPIHTTLHHQSTPHFTTTITATLHHQFTNLTTNHTHTHPPNSHTTLTTTTTPTLHHPIHTTLTNQSPQHFTTNHHQSHTTKSHHTHHQSHHTSPPITTPPLHTITLQLTTITFTQPYLHHTFHHQSHHTYTHQITPTTSHQFHNTTTSIPQSHPHIHPPITHTTFFTTPINTHIHSPNHSQRQPLTITTTTVHPSNHNHTSHPITPPLSPPNNTPTLQPPMSPTLAPPKSHHTSSTITPTTSPPQSTTTSFHHQFTHTSPPNTYHILQHQSHQHLQPTNSHHNFHHPFHTSTYTTNQHHTFTQPTHHTHHQIITTTCTHQSHHITPHFTPITNHTSTTNHTTLHHQSHHTSPPITPHFTTNHTTLHHQSHHTSPPITTLHHQSHHTFTTTHHHITTNSPHTSHQSHHTSPPHHQHHTSPPITHTSITPITPHFTTQSPHFTTNHHQSPHSHHQSHHTSPPITPHFTTNHHTSPPITPHFTTPHFTTQSHHIHHQITPHFHHQSHHTQPPITPHSPTNHHTSRTNTLSQRHTTPHNHHTSPPITPHFTTNHHTFTTNSSPPIHTTLHHQSPHTPPSPPPPSLTHTSPPITPHFSHHTPSKSPPKSQLSYSLPNPKRQKQIAGTHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0Z4</accession>
    <name>A0A3R7T0Z4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 15">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2 15">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_022033</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:33180"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2 15"/>
    <dbReference type="EMBL" id="QCYY01000501">
        <property type="protein sequence ID" value="ROT84771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0Z4"/>
    <dbReference type="STRING" id="6689.A0A3R7T0Z4"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032587">
        <property type="term" value="C:ruffle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046488">
        <property type="term" value="P:phosphatidylinositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010634">
        <property type="term" value="P:positive regulation of epithelial cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13362">
        <property type="entry name" value="PH_PLC_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000119">
        <property type="entry name" value="1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000009">
        <property type="entry name" value="1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000011">
        <property type="entry name" value="1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056586">
        <property type="entry name" value="EF-hand_PLCG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057061">
        <property type="entry name" value="PLCG_EF-hand_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF159">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23329">
        <property type="entry name" value="EF_HAND_1_PLCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23583">
        <property type="entry name" value="EF_HAND_2_PLCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 15" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="10 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 13" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="3 14" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="11" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="EF-hand" evidence="22">
        <location>
            <begin position="170"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="18">
        <location>
            <begin position="538"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="18">
        <location>
            <begin position="650"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="19">
        <location>
            <begin position="765"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="PI-PLC Y-box" evidence="21">
        <location>
            <begin position="923"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="20">
        <location>
            <begin position="1038"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="1209"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT84771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1271" mass="147432" checksum="E9D05EEE225D4550" modified="2019-04-10" version="1">MPRYLQPEEATARDLERGKAVRRFSHRHRPEHGTLKIRRETGHIIWVGAQGVREVITSLADIKEVRPGKGSKDFEKWQEEARREERAKCFIVFYGKEFKLRTLSIAAIAPDECTEWINGLKYLKEEALNVPYTIRLERTLRTEFYNMENQNNRITFRDVRNFLPRIHYKMTNNQLKQLFDQVDDRSQGEIGFDQFFDLVKKIAWDKDVDRMMFENARDVGEKSLLDKYCCEGKVSLQDFQLFLVEEQKEPEDMAGLIIKNFISDVQRDIMEPYFHVEEFVQYLFSKSNELWDRRNDSVNQDMTKSMSQYWIASSHNTDSSTEAYARVLRQGCRCIELDCWDGPDGVPNIYHGFTLTSKISFKDVINTINEHAFVASEYPVILSIEQHCSMIQQKEMAELFQKVFGDSLLTAPLSPNEKEMPSPEQLKRKIIIKHKKLPEGMDEATPPICSANDSSAQSSNEEFGGEMDLSKLSFKGDRLYLRNPVDQTAWQPHFFALTQDRLHFTELQNEEPESEDQHSGRRMLNDVSEEEWHLHEPWYHGRLPGGRAKAEELVHQNSHLGDGTFLVRFSENFVGDHTLTFWYRGKVSHCRIRVRQEGDNTRYWLKDNDSFDTLYGLIEHYKHYPILSQEVSVKLGEAVPQPNSHERMEWYHANMTRDEAEQYLGRIPEDGAFLVRPSGEAGSIAISFKAERRTKHCRVKQEDGTFIIGTATFDSLVELIKYYERNFLFRRVKLRYPVTERVIQGLQDMDPVDGTGGYVVDPAYVSNIHVKAKYSYRANKDDELTFPRHAIIQNVIKAEKEWWTGDYGGRRQHWFPAIFVEEIEPENMEERGGDNQVLGSLQKGSIDISRAGTKIEKVTGTNRWGIVSIIKLTTQTGQVVELACTSEQQAQEWVKKIESVSSPAAVNQTRQTRKPEQRIKQEMSNLVVYFRAVRCDPSKQFVYGGTHNEVSSFPENRMESLMLSCPKGLLKFHKVGFSRVYPKSSRLDSTNYNPVPMWNHGCQMVCLNYQTGDKPMQLNEGRQWQNGYMQNGKCGYILRPEFQNNPDYDPGNPLTLPNPRPLNLSIKIFGARHLSKSGKGFISPLVEVEIIGCEYDNAPKYTTRAVHDNGLNPVWGVKLMFSVHNPECALIRFVLYDEDMFGEPNQIGQATYPVTCIREGYRSVPLKNGYSEEIELASLLVHMKITREDEQMILLYRKQMITMLDEAREKNNLEMVANLEDRIQRLEQEILQHGEQYFFLDPRSRRWVNGLLPTFQLPSNHPLPQRILGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T140</accession>
    <name>A0A3R7T140_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021716</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000460">
        <property type="protein sequence ID" value="ROT84976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T140"/>
    <dbReference type="OrthoDB" id="6333343at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560">
        <property type="entry name" value="CYPHER, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46560:SF3">
        <property type="entry name" value="ZP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZP" evidence="2">
        <location>
            <begin position="209"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="45232" checksum="0A38796084DE19A3" modified="2019-04-10" version="1">MTVRPTLDLQEDQDLPTEAPDMSLSWETPSESRSALLRTPTKDTKMVFLADDHEAASRIPELLTTLSERSGSFDDGHLFPNTRSGPLSAATTTERDLRTTFDTLKTLSRTESPQEVGSEPRLESKMGGSRSDPKIGSRHNTAAYQPNHYRPLPPRQPPMRTYKPPSSGLQGASVIDKEDIFANNIYSGGPGSFKRPHRNLTRVTHIEAECQDDFMRIHVQFNGSFSGLVYSSGYAYDGDCIYVNGSGRGTYDFFIQLNRCGTLSGNEKGREDLRGRTPSKNMMWNTLTVQYNPMIEEEWDEHFKVTCEYGYDFWKTVTFPFLDVEVQTGNPVVFTLTPPECHMEIRYGYGTAGTRVAGPVRVGDPLTLVIYMRSEFEGFDIVVSDCYAHNGGNKRIALIDHYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAF3</accession>
    <name>A0A423SAF3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histone H1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004294">
        <property type="protein sequence ID" value="ROT61202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAF3"/>
    <dbReference type="STRING" id="6689.A0A423SAF3"/>
    <dbReference type="OrthoDB" id="10070354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000140">
        <property type="entry name" value="Histone H1.0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="9">
        <location>
            <begin position="14"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="66"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="114"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT61202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="255" mass="27024" checksum="E629D350365885BE" modified="2019-05-08" version="1">MPSASAASPSSRRAHPKYSEMIAAALEALKERRGSSRQAILKFILATFTVGDEKAAGVHLKQALRRGVADGSLEQTKGTGASGSFRLSKEEVKKNIVKKTTAKKFTAKKDAKKPTAKKVAKKPTAKKVAKKPTAKKVAKKPTAKKVAKKPTAKKVAKKPTAKKDAKKPTAKKDAKKPTAKKDAKKPTAKKDAKKPTAKKDAKKPTAKKSAKKVSPKNSKASNKATTKVTKKTAAARSTAKAAKAPKAKVTKKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAP3</accession>
    <name>A0A423SAP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004263">
        <property type="protein sequence ID" value="ROT61284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAP3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="983" mass="103627" checksum="8108C76DBC5FB532" modified="2019-05-08" version="1">MSRHPRPSIWHRLFSHIITSLFRPLIRHPRVLSKAHFCHYPNSLPLQLLLLPATSPVFLLSYLPTIITAPSLLLHCSNFSPSFPQLPLLSCLNFLPPSLPHFPPFLPSFPSRSPQLTSLPAQLHSHVPLPSHLPQLALPFPAPTSPPLPAPCPSPSCQTPLPPFPPRPNFPVQAPPSCPTSPPLLPNFPSPSCHNSPSACPATFLPSQLPLPFLPNFPPPAQLPSPFPAPTSLPFPAPTSPLPLPCPNFPSPSFPCPNFPPPSLPPNFPPPSAPGPTSPPPPSPNFPSPFAPQPTSPAPSPPLSLPHFPPTLPPLVRCPLPPSPFPAPIPLPLPCSNFPSPFPAPTSPAPFPRPLPAPTSPSPCPAPFRPPHPAPNFPPPCPDFPPPSPPHFPPPLPQTSPPPSSAPTSLPSCPDFPSPYPCPPLPFQPQLPSPPFLPRLPSLCPARPTSPPPVQPFPAPNSPSPLPRPNFPPLPRPTFPPTSLPFPPAPTSPPPSAPPTSPPLPPNFPPLPRPNFPPFPALTSPPPPRPNLPLAFPAPTSTPSPPQPPSPPQLPLPLPRPPTSPFPAPTFPASRLPCPDFPSPFPAPTSPPSRPNLSAPQLPPPPSPAPTSPPFPPPTPSQLPLPLHPPTPLQATSLPAPQTVPSPTSPPLPAIPPSPTWPHSRFPSPFALNFPSPSLPQLPSPSPAPTSNFSASDFPPPSMPRLSPSPFPAPNLPLPPFLCPNFPSPPSRPTSPPFSLPPSPCPRLPAPTSPLPPFPSPLNFPSPFPGPQLSSFPLPPPTFPSPPPSQPNSPLPLPPPPTSPRPSRPNLPSPSPPPTSPPPYPAPNTSLRSPRPNFPSPPLPPDFPPLPAPKLSPSLPLPPPPPPIPSPSRPQLPPSALPRTHLPSHFPAPNFPLPFPPPQLPLPPPPPTSPPPSPQPPFPPQLPPQPLPLPLPRPNFPSPPSPPLHFPSPLPLPRSPPQPPLPPHPHPLPPSPPAACAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFT9</accession>
    <name>A0A423SFT9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin/ribosomal S30 fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019102</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003504">
        <property type="protein sequence ID" value="ROT63023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFT9"/>
    <dbReference type="STRING" id="6689.A0A423SFT9"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT63023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="14410" checksum="3B351D91C9573E67" modified="2019-05-08" version="1">MQIFVRSEVTHVVENAEQQTVGDVRAFICQAEGLPETEVRLYAAGSPLDNDSFPLSNLNTDAIDVNVALKGGKVHGSLSRAGKVKGQTPKVEKKEKRKSKTGRAKRRIQYNRRFVNVVASFGKKRGPNSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGP6</accession>
    <name>A0A423SGP6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_018790</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003449">
        <property type="protein sequence ID" value="ROT63339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SGP6"/>
    <dbReference type="OrthoDB" id="6373430at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="1788"/>
            <end position="1938"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="2082"/>
            <end position="2220"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="2410"/>
            <end position="2531"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="2770"/>
            <end position="2930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="290"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2825"/>
            <end position="2887"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="3137"/>
            <end position="3164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="303"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT63339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="4118" mass="465436" checksum="6F47A21F2895C77C" modified="2019-05-08" version="1">[encoded data, 4118 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIX9</accession>
    <name>A0A423SIX9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase</fullName>
            <shortName evidence="13">GNT-I</shortName>
            <shortName evidence="13">GlcNAc-T I</shortName>
            <ecNumber evidence="13">2.4.1.101</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_017925</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11456"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="Rhea" id="RHEA-COMP:14368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60625"/>
            <dbReference type="EC" id="2.4.1.101"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">The cofactor is mostly bound to the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyltransferase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.101" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01003312">
        <property type="protein sequence ID" value="ROT64152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIX9"/>
    <dbReference type="STRING" id="6689.A0A423SIX9"/>
    <dbReference type="OrthoDB" id="6363392at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003827">
        <property type="term" value="F:alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047223">
        <property type="term" value="F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004139">
        <property type="entry name" value="Glyco_trans_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039477">
        <property type="entry name" value="ILEI/PANDER_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052463">
        <property type="entry name" value="O-linked_mannose_GnT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396:SF1">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03071">
        <property type="entry name" value="GNT-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15711">
        <property type="entry name" value="ILEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ILEI/PANDER" evidence="15">
        <location>
            <begin position="176"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF15711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT64152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="623" mass="71011" checksum="4A2DF663E9DA51FE" modified="2019-05-08" version="1">MDEVSLNEKFPRGETPPLFHAQRPRKVCCAKDSAGRVAVRVASSVVIVSCHIALRRPVHSSPLPLPAPHPGRPPAPESPRSASAKKIVAISSIKEKQLQRPFLAASDTARHKSISASNKAQRRPTSDSKKVPETASNAEIFGAVNRTGVTIWLDDQLIYASSENMFKGNKTQYHAGIHVVVLHPHRFTVLQKEQFFTWQPAAHRMLTKMIKHTQYGRIVILVGVPDFTPWFRGDATETVVSLGAQFGFLATRGETWVMVTIKGQPPLMETLITCKNFTLPRASPLTFSATVPRSPERACPWHSEPDMSLRAEFCEQYEGYADFCRCEDPIRLDPKMATALLMRFDDTVTIVNAYNYNAYPHTASDPTRIYRVQSYPYYGWMTRRSVAETMVKDWAPMDLDADWDLYIRKYHVNMCHQVVIPEIPRTKHEGGGGVHVSGNEQESSFQQRPLNTQRDVQLNMIRLWEIAYGIDMRTRIDHAQVVNITEHPCDKKPIPKHKNDTYVIYVNLTGEDDYERSYHVLGKCMGFYYPYLYENYHGTFSMKFFETPFIIVSCPSSAYCWNVDPSVIYHPTKEDLDYATKHAWRHSYALGELSVRVPALTPEEEFALDNVLFSYVPVQELVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJW4</accession>
    <name>A0A423SJW4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative helix-loop-helix protein delilah</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJW4"/>
    <dbReference type="OrthoDB" id="10063280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11431">
        <property type="entry name" value="bHLH_TS_taxi_Dei"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF147">
        <property type="entry name" value="HELIX-LOOP-HELIX PROTEIN DELILAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="88"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="29824" checksum="2EF3B5E6A98C5298" modified="2019-05-08" version="1">MAKSEEQVVEQDRAASLGNSVDDNNNDDSNSSSGSSDDGSKSQAIEASGGKYQLRPRSLHARRLCDGGDWSFQDAIRSKPRPPPLSRYRRKTANARERYRMRQINTAFESLRGVLPSWVCSRRAASDMTKIATLRLASAYIRSLQDILDGNAPQDTCSWVLSSILQDASRPHDDPERSSSASKAPGSDDACAHSEADLVSLLCGSSGAQDGLESLSYLAPMAESDTVTLLLLESDSHRHWSDQHPPKGRADRVWASDSVLRCACAASVVSQEGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLH1</accession>
    <name>A0A423SLH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003152">
        <property type="protein sequence ID" value="ROT65032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLH1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="612" mass="66539" checksum="1646656582753075" modified="2019-05-08" version="1">MRLPPPLVYGLPLRDCLFAPRDGLPSHEGGLPTPVSSCPTRWLLPKRWFGPNAHASGLPPRRWLCPKPGAFAPRGVCPARWSCGGLGQTTAWGKPPRGANHRVGQATAWGKVIALGQKPPFGRKPPCGSKTTELWWQTTTVGQTNRLGPKPCRCWANTSRGAKPLFGQIQAALAKPPLPQYHRIGANNHAAWGKPPRVKPSRVMSGKPPVWGKPKPALRGQTTSMGNTTAWGNHAVGAKNHRWGKHTCVGQDPRVRAKAIPRGAKLTVMAGTQTTRVRANHPWAKPPPVGTKHPLCANHRVGPNQPRRGQTPSGRFKTQKTTCNHRIGVNTAWAGNNHRLRAQTTAVVQNHLTSRANTTAWGKPRVCGNHRVGKPRVLRANHALAGKPPFGCNLYTRLSVANQPALGPKPTQRRVVSRQVHSPASTPYGQKETSQPLTLLPSERPVFTVYPGAVSNSTHFLSLTTKVTHKIYLDDSECDRAIGLSIIGSEDAVTLEGTSVHSNATEDEASQRHAPRAPTTGKPSRQPLTVYPSTTFRYRGASCHLSTHSLTHPGHPPGTQPFAQLALKALDREHRWGCSTLTTQPPRYPKHCSASASTRVVYLHMPVCTLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SML2</accession>
    <name>A0A423SML2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA polymerase</fullName>
            <ecNumber evidence="13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_016659</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01003093">
        <property type="protein sequence ID" value="ROT65379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SML2"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05778">
        <property type="entry name" value="DNA_polB_zeta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05534">
        <property type="entry name" value="POLBc_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000002">
        <property type="entry name" value="DNA polymerase zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000024">
        <property type="entry name" value="DNA polymerase zeta catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="16">
        <location>
            <begin position="550"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="15">
        <location>
            <begin position="795"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="17">
        <location>
            <begin position="1261"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="205"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="375"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="415"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT65379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1397" mass="155223" checksum="E10491CA5A92B22B" modified="2019-05-08" version="1">MSTERGQPSGVAAAKPEEEMKFKDSSKSEKHKKVSSVVPLSESDSSSKKDPSKSSQNAVLSENIKSKGEQDMKNSNRTSANSQSKGKKDDDQYVPKAISSEKRAKYIPQALTLPTSNIIEEDEYSPLPVGLDKPTPEYIPSDISEKSKHLLQEEEYVPQPAKVIPYGAGGSSTPKDTNKETLDPQSNQQLVVTHSIDKVIPGFYREQEGGDSSQGNKDANSGKDPSGSGSSKKNGARKLKTKVPGPGAASGGSKVLVYVPPPPTYEHIVNTLANYDIPEVVHPTAFCSNPTDVPPKSLEIGGKVLKLQTTMTSDLGKTRTAEESAVVGKNPSAVSGQRSTKRRVSWENDVPLTTVATEPKRRRVSFEGMSDTDLGVQRLDRDGSQKKDKFGSLELVPEEIQEATDANMPPKQHQPEGSTLATTSETSGPGMKKGDHFQGGTQQSEKNKSPQMSEVRADPSLSDTEDFIDSSQPHVSLTPSVPSKIARQGSQLSSDSSLRRQLMDTQFRQQFLSFSEGPASLSQGIEGPTLNNTYGFRFSTQNLREAKALHEHEFLTVMCLECHVTTRPGLLPDPQLDPISAVLFTIIQDVPDDHPTPQKLKGALVVSSGGCDLITRCGITDLSVLHVDSEIEIFKEVIKLVTTWDPDMLVGYEVQMSSWGYLLERGTALKLEIISQLSRVPEGSSSHYAEDLDEYGADHTSQIHVTGRIVLNVWRLMRAEVALQSYTLDNVAYHVLHTRIPSFPHDSLRRWWSEDTTRWRTLEHYLNRCSLTIELLHRLDLIHRTAELARLFGIQFYDVLARGSQYRVESMMLRLTRRANMVAVSPSIQQRAAMKAPEWIALTLEPESRFYTDPVVVLDFQSLYPSMMIAYNYCYSTCIGRINNLDGPQPIEFGTSHLRVSPQELSKFVDKVNISPCGIAFVPASVRRGVLPMMLEEILNTRIMVKRMMKVYKNDTSLQRVLHSRQLGLKLIANVTYGYTSANFSGRMPCSEVGDSVVSKGRETLERCIQFIHSNKAWKARVVYGDTDSLFVHLPGRTKDQAFVIGSEIAEQVTQMYPKPVKLKFEKVYLPCILQTKKRYVGYMYETRDQRDPEYDAKGIETVRRDGCPAIAKILEKSLRLLFETKDVSQVKDFVQRQQWTRKDRRKEPRTGERVPYVIVYGAPGLPLIQLVRSPKNVLLDPALRINSIYYITRAIIPPLERCFSLLGVDVNLWYNDLPRPAAQQNKAIVAEASHGTLVKSVASHNSRGMSIARYFTPVSCVACGATTMTAPTSQGPGLCPDCKTKPQTTVLCLNEKIRSYERALEHLGKVCEGCLGCHVADIECISLDCPVTYKREGARQEHMLASQLQKTCAPETTSPNHLFDLTFSAIVLVVRADPYPLSPPLPHPSLRHGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SP48</accession>
    <name>A0A423SP48_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IkappaB kinase</fullName>
            <ecNumber evidence="3">2.7.11.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_016013</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19073"/>
            <dbReference type="Rhea" id="RHEA-COMP:13698"/>
            <dbReference type="Rhea" id="RHEA-COMP:13699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.10" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003002">
        <property type="protein sequence ID" value="ROT66006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SP48"/>
    <dbReference type="STRING" id="6689.A0A423SP48"/>
    <dbReference type="OrthoDB" id="267381at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008385">
        <property type="term" value="C:IkappaB kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008384">
        <property type="term" value="F:IkappaB kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033209">
        <property type="term" value="P:tumor necrosis factor-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17046">
        <property type="entry name" value="Ubl_IKKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000147">
        <property type="entry name" value="Inhibitor of nuclear factor kappa-B kinase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041185">
        <property type="entry name" value="IKBKB_SDD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046375">
        <property type="entry name" value="IKBKB_SDD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051180">
        <property type="entry name" value="IKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22969">
        <property type="entry name" value="IKB KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22969:SF17">
        <property type="entry name" value="INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18397">
        <property type="entry name" value="IKBKB_SDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="13"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT66006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="666" mass="76535" checksum="7600F133639B80CB" modified="2019-05-08" version="1" fragment="single">MAAAEDRPPTYPWLKDKVLGTGGFGTVTLWRHNDTGETIALKKCRWGTPGTGTENILTPKHVERWEKEVEIMNRLNHQAVVRCFPVPDELTGPQGDLPMLCMEYCSGGDLRKVLNKPENCCGLREAAVRSCIRDMTEAVAYLHSMRIIHRDLKPENIVLQDVDGKTVYKLIDLGYAKELEQSSVCTSFVGTLQYLAPELFLSKRYTCTVDYWSLGLVTHEIITGIRPFLPNMTPVEWMKRVRTKQSHHVCVYEGRNGEIQFSSHMFPECHISQPLRTRIEEWLRIMLEWDPVLRGQVLDEDSAKQFVAFNMINDILNKKMIKVFVVDLCRLLEYEVTESTSLSEVQQWVARDSGVLVDDQRPLLPRGQPPDPTRPAIQCWAPPDEDEWLLYIFAEGMTRPQVPPHFPPLVEAMLREPRTAVEYQTQRRMWAHAVFFLHREARLLTLLTQAQKVSMLHLMSGHAQLTKTGQRMLSDIAKLQARHHLFMEALNTDLDYYDEQASSGRLTSEKLYSGWREMGEVTLRQVHAVVERVQQLEGSLTALNTRILELQCSPFARARAIDSLDSVLTAGEDHYCNLRRRNKEQRATPHDNTDMCKLLLQALRKRDRLQQDLYKHVEKQSECCSEVAALSSPLEAVLQDAARTAQHISSLQKQRQKDIWKIMEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQS6</accession>
    <name>A0A423SQS6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative SH3 and multiple ankyrin repeat domains protein 3 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_015427</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Postsynaptic density</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002918">
        <property type="protein sequence ID" value="ROT66548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SQS6"/>
    <dbReference type="OrthoDB" id="445896at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043197">
        <property type="term" value="C:dendritic spine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0014069">
        <property type="term" value="C:postsynaptic density"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035255">
        <property type="term" value="F:ionotropic glutamate receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030160">
        <property type="term" value="F:synaptic receptor adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06746">
        <property type="entry name" value="PDZ_SHANK1_3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051569">
        <property type="entry name" value="SHANK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24135:SF28">
        <property type="entry name" value="LD13733P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24135">
        <property type="entry name" value="SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="2" id="KW-0770">Synapse</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="479"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="9">
        <location>
            <begin position="587"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="8">
        <location>
            <begin position="1557"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="747"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="886"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="958"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="392"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="747"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="802"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="958"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1005"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1089"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1106"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1142"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1217"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1235"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1269"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1280"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1331"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1360"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1379"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1410"/>
            <end position="1429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT66548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1747" mass="190206" checksum="6FEE2B49095FEF43" modified="2019-05-08" version="1">MTTSIRLGFSFVFFQSLIRSSSLSLCSLSVFCLPALSTATFTSYSLSLLCPSLLELRESFNYGLFCPPQNGRAGKFLDEERPLGDYPLTAPIGYLELKYKRRVYKMLHLEEKALRALHTRANLRRFLDYVKENNVEKVTKLCAKGLDPNFHCQDTGETPLSLAARIKKPAKMVMSIVNGGALLDYRTKDGVTAMHRAVQANNFEAVKTLLDLGASPNYRDSRGLTPLYYSVTHNTDPLLCEALLHDYAVIGACDNQGWQETHQACRNKLVQHLEHLLFYGADMNAQNASGNTPLHVCAVNNLEDCARVLLFRGCDKNALNYANQTPYQVAVIAGNMELGDVIKNHSIEDVVPFKEPPKYNPNRRISGAPLSRTHSDPRLEVCAVTKPPSPSPSSRSIPPFSSASSLSETSTGSSSTCTHPSEMDSEECASALGSASLNAGKWAGMDCCDMVSDSSGVCTSNSGSAESYDATPTDITHFDVGMLVVCLHQYTPHKQGHLDINAGDILEVTGSTDDGMLEGVIRGVTGVFPPQCVQEVRLRNPQAVRESLIAPQVARVQGRREMLVHQHYGTAPRLRKPVVNQASEPRTVVLHRGKKGFGFVLRGAKATSPLMERPNERGPALQYLDDVDPGGVADLAGLKKGDYLLRINGEDVSQASHEHVVNLIRKSGDLVQMMVVTPAPVTFTPHKPPIGNLGTIRRGCQTLPRKLPAEALDASMRENGDLMSRSAGQFPGGGPYGSSHYGVSHYTSGSQYGTPQGTPTIGTPVGTPPGLKVASIKARPSSKRMTAAEMEDMMTQSGSLPSSPPSTPTGRPPRVYASVAEMKKAKALKARQPLDLTRLHKGFHSTPDLKAEVTGTLPAFTIEEKRKSVSQEDLFVTALNERNSRHSLVCPPPHSSTLERITVGSPESKESWQSEAMPVSPGVQSSFRPTDCAKLYASPEEIKTVGYRSPEMMATLNRKNASVKSRSQSLPPSTNRPSVQRGSPDKDTSLDSGIYLTTYSTFRGTEGETSRSREVVSPSSAGKAPVSDTVTYARPKNNKSIHDRAESSSPSKAYTGPGSVASPAPDIPEPDYSSDEDHTYNSQDESQSKKTRTLKKKKPTVAFSPNLVTSTSESSDVPHYAAPAKHPTPLAGNFKDLIAQKAAERQARQDDGPEQTRQKEKTVPTGTKARPVPVVQREDSKSTLKMKNSRSCPHDFNLEDGDNSSSGVSSDQDVHQESNYVTVINTESDTISANKTDRFVRHGTRDDSSEASESSDEASDRTWILTNEKGSDSGKDSDSNGARRSGTLTRNAVSLVKLPPPQETTEPDLDTELDVGQGRIMSRSVDQDTISTLSSLSSLSSGSGSTGEREMQHSMHAGQVPSSAPSSLQMRATLPRPPSSASSSRGSSAPPVSQAIRATVTGTLGRSRPTTREQHWEVEGEPMAVREKSAPPTSRSSTLERDSYKKSTNVDTGETEYERSIEESLQLIRMHMDSLNEVNTLAGVPTRDQAGGGEMVLAPPPEFCDMSMAGAQGRKNNKTVIHIGEEEFDQPGRRGPNVHEEEEELLPRFRHKTLTEWTTRDTTEWLESIFMPEYKDSFEEQDIDGKKLMDINNESLINLGVRREGRDCAFPRSSSLAGGSGLFAWKRIGGSEECLLSLEEWVVRGIGGSGGSEECLLSFVFPRSLPKVLCLPDGRTFRPSGVILASVHYSLVGPSSRSPKRKQESRSLLSFIHRNDTVQCIPRRTTHAFDMKFAHEGGDSSPRGTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SR84</accession>
    <name>A0A423SR84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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            <end position="62"/>
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            <end position="101"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="135"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="329"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    <evidence type="ECO:0000256" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
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    </evidence>
    <sequence length="375" mass="41124" checksum="799723155B384679" modified="2019-05-08" version="1">MVRRRGKGRISFRLVCSGFPGCSNEGRAPPLPLPPFPLVYLLPYFIPLFHLLLLSSFPLHYLSPISFPSFTYSSSLPFPLHYLLPFFIPLSHLLLSSLHFSTLTTSSLPHCSVYFPPLFPSPLILSLPLILLPAIPFSPPHSSLPLPTSSPFPRLSTLPFPLPLPTNHPPPPPPFPSLAPTRPPHPPTGPCFHPAFFFPFPRVRIFGSPEGTGGHRSALDTADHSIQRTLDTADHSILRSTRCSGPLDTAVHSIQRSTRYTADHDTLDAADPSIRSLDAATSIQRSLDTASHRCSGPLDTRTTRYSGHSIQRTTRYSGPLDSGGPLDTQRTTRYAVHSIQRTLDQRTTRYSGPLRYLSLVTSAPGNNIGGADEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
    </protein>
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        <name evidence="14" type="ORF">C7M84_014794</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
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            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="entry name" value="palladin isoform X1"/>
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    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
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    <keyword evidence="4" id="KW-0677">Repeat</keyword>
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        </source>
    </evidence>
    <sequence length="1958" mass="214641" checksum="E1DFD7DAA844FBD2" modified="2019-05-08" version="1">MTRSSRSFGDYSTVPTSQSDHVVFWLLAVVAMDQGGHERFKKLAGDFRFVASLDIEVTVPPLIGPDLPKEEVLFTVNHDPEQEPEPLTLPCRADGLPAPSYSWLKDGSPYDWHDDGDDDGDDDNGAGERVEMLQGEGTLVFHDPQPEDEGVYQCIAENSVGVAHSDLITVRRAVMGSFPKAEHRIVTAAEWQPLKLPCTPPEGYPEPTLHWVLQNSDGGLRSLDSERITVDEEGTLWFSYVTREDASGDALYACAASSATSGQKMYLVKDEDGFLEVLEDPPEDDSVTVISLPTEYRMGNWVYLNVSYPEDEESTHPEASIAPVKQYLSPRQITVLEGEDVKLHCLYGGYPVPDIRWWRESRADVEDDQLEHFGKILVLEDVDHEDTGSYYCQASNEAGESEAHQFTVYVEAAPEFIVEPEVVNLPEGETATLSCEAKGDPEPIITWTKNGQPMDTHETTLMFDRLSFADKTVIACNASNEHGYVYKSVYLNVLSLPPEWMTEPKDVYVLEGGSAELECEAFGSPDPEITWARRDGDEKTVIHDEDPRYDVNDHQLLINTVDDTTDGTYVCTATNKFASIESEAKVAMRSMTRAEVSIKDERVEAGDHVTLDCRVAIDPLLKSSVTWLKDNHKIENWVLEIEEVHGHDSGVYTCRVHTDLDDVTDDLILTVEGQAACAFVLYGHLRPEPPSLTNVECNPRSAYLGWASTGDNNAKLQGFVIQYRTRLHPEWKDAKNQIPAAETSFTVNMSPGLNYTYRVLAFNRVGMSEPSEDTAECSAPGLPPDFHPENVTVSGPAPGVLHVSWEEMEPEDHNGPDFQYKSELELENLPPYQEYEVKVEARNSYGEALEEADVITGFSGQDEPEVAPAKVRVADADATDVVLTWKPVDEDSLNGPLLGYKVEYWEESDDSDPEEILTTGPVARAELTGLRPFTNYHARISVANTEYTGPSSDTVEFTTAEGDAGAVSDLEVRAMGADSLVVKWDAPDDPQGVILGYEVRYQKVDEDGEEEWEHYEGHIPASTRMVKLADLEEEVSYEVSVAAVNGAGEADEDEENVLLEDKNADGVIDEDDVGDINNDGIIDEEDLDEADIDNDGDVDEDDLKIADKDGDGDVDAADVLDLDGDGRVDGDDLEVTDRDGDGDIDARDYKLKSIFLSDVDGDGDVDSDDVIDVDDDGDIDEDDKAIADIDNDGDVDEDDVKAADRDGDGDVDIADIGDEDDDGDIDGQDVILADKDGDGDIDASDDDEEDSLLEDRNGDGTIDRDDVGDLDGDGDVDLEDFQAADIDDDGDAADIDDDGDVDEDDLKHSDRDGDNDVDASDVQDLDGDGFIDEDDLDVKDKDGDGDIDRDDFRLRKVILADTDNDGDIDEDDVLDTDNDGDVDQEDIDADKDGDGDIDNEDDDGEHVLLSDIDGDGDIDVTDIDNDGDVDEDDRKAADVDNDGDVDKDDVAAADRDGDGDVDAADILDVDGDGDVDAKDLMAADKDGDGDIDQADVENMDVFLKDTDGDGDVDEDDVLDTDHDGDVDEEDIAVADIDNDGDVDMDDVIAADQDGDGDVDFKDIGDEDGDGNIDGDDLEAADRDGDGDVDAADDGRGVDVVINWKPDFDKHPGVDFYVESRIQGTSEWQSSPVERRHLYQTLSGLDPRRNYEVRVVARDGDYETPSGITVIQASEDMGQEEPTVGAVVEDNPILWTWFVIAVMASVTMICVVFFSMWVYSHRMARVAELRASLYEGYEPAQPEPTKKDADVEAAKPEEVVEDEMTANFQRKQLAAMMKRQETVQSVDSFASHDDDFAEYGDESMVGQTETLVAISHPRAVRIPNGLACVLADPRGLRVSGKAGSLEEDLGSLRGVRFISIALPVSKVPDNFPFSFRVNLESCQRLLPWPLSLGPSPASPSFSNRASFSPAGRFTDDGSLIHQRVVAAPLSRHHNPVIISHLSLITIAFVSSRVQTHSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSL9</accession>
    <name>A0A423SSL9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hypoxia up-regulated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_014730</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002834">
        <property type="protein sequence ID" value="ROT67204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSL9"/>
    <dbReference type="STRING" id="6689.A0A423SSL9"/>
    <dbReference type="OrthoDB" id="10262720at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034663">
        <property type="term" value="C:endoplasmic reticulum chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000004">
        <property type="entry name" value="hypoxia up-regulated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="68"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT67204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="511" mass="56047" checksum="FC5289F74C201572" modified="2019-05-08" version="1">MPGLYDPPPPDFLTCTCSLEPAIHTQGLQLALGPRALGTLGPRYGRYSLQGSLRVCGLCTGLHMGPQPAPSKLASDWKKPPPEESSCPGAPRCPPAFLEAPTRPPQSPEGPGAPRASQSGRRRPANQAPPHESGRRGTPQPSSSVHAVSDRENHRCHGRATASTLSSWAEGDTTMMVPDVRWTMGLSLLVLLGIIGSSSGVTIMSIDFGSEWIKVAVVAPGVPMEIVLNKESKRKTPGAVSFRNGERTFGEDALTTGIRFPANNYFYLLDLLGKKIDNPIVELYKKRFPFYNIEADPERGTVVFRHNDDTTYTVEELIAQMLAYAKDMAMSHTEQRIKDCVITVPPFFNQVERRAMLTAAELAGLKVLSLMSSNAAVALNYGMFRRKEINATAHNILFYDMGASSTIATIVSYQTVKTKDRGYTETNPQVTVLGLGYDRTLGGLEMQMRLRDYLAKKFNEIKKTPNNVLESPRALAKLMKEAGRLKKVLSANSDHLSQIEGLLDEEDFKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SW03</accession>
    <name>A0A423SW03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002681">
        <property type="protein sequence ID" value="ROT68365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SW03"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="622"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="655"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="695"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="727"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="764"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="805"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="850"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="879"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="907"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="928" mass="105030" checksum="7378A4E43744A0C1" modified="2019-05-08" version="1">MSTILLLYLFIHFSSLFLNPGFYYSFLHLLPSPFSFALSFISFSLSSPFPSISSLLLPSRFSPFDSPISAISHFSFPSLILPISPSPVIRSFPSPLILFLPHFSFSLLHFHFISPSFSSFPFFLLPISHSPFIPLLLLLLLSISLSFPFSSPLSSPFPDSHFSYFSPSLFFPILSFSLSISLSPLPPFFISLLPLHFHSLSFLSLFLPHFLLLPSISPFLFSLFLPPSLSSFPFLLFLSPLSSPSSSFSRPHFPFLPFLSLFLPISLPPPFLILFFSSPFSSIFSPSSIFPFLSLFLSLILFPFPLPPSSISRSHFSFSSLFFLFPFPPSPPPFHFSFSLPLFFPHFLSSSPISHSFPFLHFPFLSLFFSPFLPHFSSSLLIPIISLFLSPLSSPFSSPSLHFPLFSFSLSSSSLPPPFSPSPSFHSHFFLFSLFLFLPISPLLPPFPILLFLSPYFFPIFSPSPPPFPFLLFSPLFLPISPFSSSISHFTPFSLPSFFPDFSSFPLLHFPIFLFSPLFLPHFSFSLLHFPSPFSHSPFFLPTFLLFFPFPPYYHFLLFLPLFLPQFLFFPPPFPSSFSPLILPHSLLLSPFFPFLLFPSPLFSPISLLPPHLPLHFPSPPFLSLFFFPILLLPPPFPILPFLSPLFSHFSFSLLPFPISPFSLYLFLPPFLLFLPPPSHFSVFSPLFFPISPLLPPFPHLPFSLLFFTISLLSLHFPFSPFSLSSFFPFILLPSIHFSFFSSISPSPSSNFPSLFSPLILPHFLLLPSSISISPFSLPLFSPHFSFSLSPFSHFSFLSPLSSPFLLLPPPFPIFLFLLFFSPSLLFSYFPSPLFLAHSPSPSSISHFSFFSPLFLPHFSFSLLHFPFLLFLSPFSSPFLLLPPPFPISPFSLPLLFPPIFLSPPPFPIYFLFLSPFFPFLPSPVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZB6</accession>
    <name>A0A423SZB6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative carbohydrate sulfotransferase 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002545">
        <property type="protein sequence ID" value="ROT69610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZB6"/>
    <dbReference type="OrthoDB" id="6138663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="308" mass="34271" checksum="8E73201DEAC3CBC5" modified="2019-05-08" version="1">MRLKKLQKLKAPPPPLQRARRGRRRRPRKILVLEHRRPLRLLLPRGTHRAAPGLTLLLRADDVQLQGHDRRRESQGYLEPPQENLQLPVRPRLAGLCAEPESGAQEGGEALRTFARGICALLPQESVPQPDQHCRQGHTDAGFVAGRPPAGGGAGAEGRTPGEGPQSHLQVLQNDLQMIDTVKKLFPGRVTSVKYEDLCLDTKGVATTLWRFLSGAPEADLPPTWAHYLAEHTDGANRRGNAYSTWRDTRKEAEAWRQEIGESLLLAVEDHCGGAIDLLGHNKFHSLATARNLSNPLRWTRKPLYSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T204</accession>
    <name>A0A423T204_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011190</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002414">
        <property type="protein sequence ID" value="ROT70514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T204"/>
    <dbReference type="STRING" id="6689.A0A423T204"/>
    <dbReference type="OrthoDB" id="6506757at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="14">
        <location>
            <begin position="77"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="54215" checksum="7922E6D93CC0D087" modified="2019-05-08" version="1">MLLRQSKKTKHVLGILKTGEGDWAVYMNLLYKAQPLTRLTTWRNGSFTSQKPLFPDKLNDLGGVVVKVVTFEWKPSTFNQLGRDGEVEDRFGVDIEVVRAVAKVLNFNIEFVEPPQGELWGSRMPNGSWNGMMGLLHRAEAEIAAANLYVTSRRLSVLEYTDPYDSELSCFLTRTEPPLPRWHALAFPFHLWTWLALLLSLLATGPVFYLLARNSCHVPGEAKDTHSLPFAYTYVFGVHCSRSMALLPRSPSTRIFVVFLWLYAVILTLAYSTNLTAFLIVTTSPAGVETIRELYESGKEVAGTGYFYRDELASSGDPFLQGLTDRYLSSTTVDEILKKVVSGGTVYLQNRGSLEYVRATKFSSRTLQGVRIMKAVPRLPPSPPGVLRPYSIALAVQRHSPLKEKISRAVGHLQSGGLARQYFLQSLRRAAASEGREGSELTLGDAAEGDESSEDVIPLTLDHLQGVFMLALLGWGLSCFVLLAECVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2H2</accession>
    <name>A0A423T2H2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alanine transaminase</fullName>
            <ecNumber evidence="8">2.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010970</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-alanine + 2-oxoglutarate = pyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:19453"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="2.6.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-alanine degradation via transaminase pathway; pyruvate from L-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.2" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01002392">
        <property type="protein sequence ID" value="ROT70732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2H2"/>
    <dbReference type="STRING" id="6689.A0A423T2H2"/>
    <dbReference type="OrthoDB" id="1732682at2759"/>
    <dbReference type="UniPathway" id="UPA00528">
        <property type="reaction ID" value="UER00586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004021">
        <property type="term" value="F:L-alanine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000012">
        <property type="entry name" value="alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000010">
        <property type="entry name" value="Alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="10">
        <location>
            <begin position="26"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT70732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="44804" checksum="2C78498D713B22E7" modified="2019-05-08" version="1">MPSLLDDPNLPEDAKSRARHVLEGCKGGSLGSYSDSAGIEIIRRHVAEYIERRDGFPSCWENIVLCAGASEGIRGTMKLMINHENGVKPGVMIPIPQYPLYSATIAEFDLHQIGYYLDESKNWSLDLAELKRAYDDAKSVCTPKALCVINPGNPTGNVLTRENIEGIIKFAHERNLFLFADEVYQDNVYAEGSKFHSFKKVLMEMGEPYNKMELASFMSCSKGYMGECGLRGGYAEIINLDPAVKAMYLKSISAKLCPTTLGQAVMECVVNPPKEGEPSYESFMKEKQGVLSSLATRAKMVADTFNSVPGMSCNIVQGAMYAFPQITLPEKAIEAAKKEGQAADVFYAFQLLENTGICIVPGSGFGQRPGTYHFRTTILPQPDKLKVMLEKFREFHSNFLKLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2Z1</accession>
    <name>A0A423T2Z1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative neo-calmodulin-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_010943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002388">
        <property type="protein sequence ID" value="ROT70765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2Z1"/>
    <dbReference type="STRING" id="6689.A0A423T2Z1"/>
    <dbReference type="OrthoDB" id="6359269at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000527">
        <property type="entry name" value="Calmodulin-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="134"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT70765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="253" mass="27761" checksum="06D13275043981FA" modified="2019-05-08" version="1">MDVNNQMARSKSGSVDAVPKSQAGKGGTAQKIGTPSKNNNNKQVTKPSAQKTQVKQAPSKQVQQTKGAGGKKGKKGHKHQQYDLIVTIDLVEYGLTDDLVAEFKEAFMLFDKDEDGMITTAELGVVMRSLGQRPSETELRKLVGEVETCADGTIEFNEFLQMMSKKLKDIGNGDELKEAFKVFDKKNSGYLSSTELRHVMTSMGEKMSEQEVEDMIKEAAPNGDGRVNYEGGARLLLVRSSYALLFGKSGRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3W8</accession>
    <name>A0A423T3W8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_010624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002346">
        <property type="protein sequence ID" value="ROT71075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3W8"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016199">
        <property type="term" value="P:axon midline choice point recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008406">
        <property type="term" value="P:gonad development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035167">
        <property type="term" value="P:larval lymph gland hemopoiesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007526">
        <property type="term" value="P:larval somatic muscle development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045476">
        <property type="term" value="P:nurse cell apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007464">
        <property type="term" value="P:R3/R4 cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045467">
        <property type="term" value="P:R7 cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF111">
        <property type="entry name" value="LONGITUDINALS LACKING PROTEIN, ISOFORMS F_I_K_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2" id="KW-0221">Differentiation</keyword>
    <keyword evidence="3" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="7">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="170"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT71075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="393" mass="43180" checksum="BE22EC965A85B599" modified="2019-05-08" version="1">MCRDDLQPRPAAFLMMGSDQYCLKWNNHWANLIRVFNSLLQSETFVDVTLACEGRHLKAHRLVLSACSPYFKELLVAHPDKHPIVILKDVRYSELRTLIEFIYNGEVSVEQHDLADLLCTARELQIKGLADNRLPGAAPAAARGGRRPPTTGRRRCSRCCSPTFLRRRRRSCRRTGRGRRAEQQTVHRRGGAVGASVAGAQQERRQHQPRLQLGRRKGNAVHIQVVLGGPVHRGLRDFKLAHSGEDTDDDRGAMTIQSPEVILEEGEVGAGSSGPPSTVPSPTLCGSGIGSASLTTTGLGGPLPPQVALLHQALAPSYHPLLHYFPPGLLEQHHQQPPGVSPPKDLMHFLDVMKAIPPPRLPLAALGAPSAGVPVWVFLSPGYQAQWQRPQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4F2</accession>
    <name>A0A423T4F2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome b-c1 complex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Complex III subunit X</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_010412</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCR10/QCR9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002316">
        <property type="protein sequence ID" value="ROT71273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4F2"/>
    <dbReference type="STRING" id="6689.A0A423T4F2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.260:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.260">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008027">
        <property type="entry name" value="QCR9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036656">
        <property type="entry name" value="QCR9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12980:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12980">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX, SUBUNIT X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05365">
        <property type="entry name" value="UCR_UQCRX_QCR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81514">
        <property type="entry name" value="Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="58"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00076299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT71273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="26737" checksum="2182A9476371152B" modified="2019-05-08" version="1">MGVKFHKNFPHFLTPGCCSCHTPSSPHTSLSLTNSHSAHFLSPHAPVPPANTCPRACTPAGGSVSRTPVTRGLDSALARSPASGPPRVLRARSHLSIPGCSASAHPPYAHLVLITHTPRCRPRRLGLRGSPRPYYGRHAMHRIMLVVASHTCLQSQSPLLAKSPSVVCRSSSSLPTKMSGVIGKIYQNIFRRTSSFVFAAVCGAFMFERGFELVSDGIFETVNQGKLWKHIKHRYDQPVEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5I7</accession>
    <name>A0A423T5I7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative serine proteinase stubble isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002251">
        <property type="protein sequence ID" value="ROT71769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5I7"/>
    <dbReference type="OrthoDB" id="10002959at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000006">
        <property type="entry name" value="Serine proteinase stubble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="28"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="270" mass="30073" checksum="3C9A10DFE168D515" modified="2019-05-08" version="1">MPPPPTMPRLTPLPPAECGETYARTNRIVGGGDSSFGSHPWQAAIIKESFLSKRISCGGALLNKRWVITAAHCVYSTPTSNMKVRLGEWNVRKQNERLPHEDFEVIRKEVHPNYQAADFQNDVALVKIGRDVTYKEHIIPVCLPQQGDVFTGQYATVTGWGRLSHGISSTPEVLQEVDVEVLQNDVCQEWFKEAGRRETIHDVFLCGGYKNGGKDSCQGDSGSPLTLMQDGRRHLIGLVSWGIGCARRNLPGVYTNLALFSNWIRRIIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAS9</accession>
    <name>A0A423TAS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002015">
        <property type="protein sequence ID" value="ROT73603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAS9"/>
    <dbReference type="OrthoDB" id="6363485at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="624" mass="64607" checksum="CE96F6C0B3680AA5" modified="2019-05-08" version="1">MPVLRAKSPRVEGGRCYPKVCWSAVTRATHWGISTRSSAPETHSAKSARSAKSSQIFNGFPVDSDQGGVTSRPDGDSEANGCRREMGAPRAPAAPARHQGGVHAAQPLPASALPRGAQQHRQARLQPSTPRSATPSRSSASASTGKGLSNGGAFRAPGTRLRFFSRSVAAPPPPACDDHHCDVDDLCDASSASDCSSASDAHSSSGGHSLRDSCSGSDDDGACSGTCCIPAGDAPCCLLPCAHTSAGAKIIRSAISVPSTRHCGYGAYGNENDASIAKMPLRARSGEGVTTAACMGALSCRLNGARDGGAGRAATPNGHCETQVLDRCDEEAPAPRHPRAESEPSVSRDKDASDRNTAPRGIVCRIGRQQDSSAAPMVRQDTFTIERGQGGISPRGEGGLSLPMLSRPLCPSPTPTPSLATLRPRAGQSGTSNGSKLRPPATHYREAARLSPARSNGAASAPYSRGSLSQPRAALAASRGGRRRSASENGDLGAEERLGGGADTPPWEPHHVAKGPRGSGNTKRGAPYSRSSVSSDEHDQQAASGQQKEDPPPHQPTHRGRRAMKITLREEATKKNTNLTTPASRTRSGSRSSGGSSPATIHGRAPHKTATAALSLFSQQVRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEV3</accession>
    <name>A0A423TEV3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001819">
        <property type="protein sequence ID" value="ROT75019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEV3"/>
    <dbReference type="STRING" id="6689.A0A423TEV3"/>
    <dbReference type="OrthoDB" id="6370583at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33776">
        <property type="entry name" value="ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33776:SF3">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019158384" description="Endonuclease/exonuclease/phosphatase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="75"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="42819" checksum="42C9FC6B2EE3D6B2" modified="2019-05-08" version="1">MLSVDSFLLLLIPLVLPYPSLSPVTGLQDIRHTHHTHNRSTPLTPTHTLSSRLTPFIQPGVMPGRKSRDQLTIISANVRGLLTNIGDLVNSHVIPRTPDIVATVETFMNESVPDNFGHMKGYTRWHRRDRTHGTFGGVAVSFHKSLSVQPLDVDLPNHLEIMFFKIWAQHQTVLLCVCYRPQWQGSEPIVFLQTHLDELLQLHTCNHVIIVGDMNQHLVARSFEELLTVHGLFNHVDFPTHISGSSLDPVVSDLPDSVVTCSPLSAVGSSDHMAILTLIQITPQRDAAVTRTNWLWGKADWNGLCNALQQEPWNSILIIDRFGQVVGTRNHNPLIMMFRIKYYPRNQTPLNHDVFGQVFPAINNPLNHDVFGTSFPAITTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFD6</accession>
    <name>A0A423TFD6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Box C/D snoRNA protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Zinc finger HIT domain-containing protein 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_006318</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with FBL, SNU13, NOP58, NUFIP1, RUVBL1, RUVBL2 and TAF9. Interacts (via HIT-type zinc finger) with the RUVBL1/RUVBL2 complex in the presence of ADP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the BCD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001807">
        <property type="protein sequence ID" value="ROT75151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFD6"/>
    <dbReference type="STRING" id="6689.A0A423TFD6"/>
    <dbReference type="OrthoDB" id="272357at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23023">
        <property type="entry name" value="zf-HIT_BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.190:FF:000001">
        <property type="entry name" value="box C/D snoRNA protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057721">
        <property type="entry name" value="BCD1_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF3">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25790">
        <property type="entry name" value="BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="14">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00068630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00077531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT75151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="211" mass="24258" checksum="B56605B838B7352C" modified="2019-05-08" version="1">MTDTQEKDISSRLGMCSVCAHTAAKYTCPRCGVKTCSLPCVKSHKKDAGGCSGVRDKTVMVLKEDMDNLTLLSDYRFLEEIDHKLEDNQRHPLRRYIVPRQIKGKPELPFFLNNLRNEAAKRGTTLRFLPNHFSKHKENSTRFIAKEGIIRWHIKWVFHQADITFTNTQVDENTPIITLLAHYMEPSDALTPEETEKLAYYHSASYSRIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ03</accession>
    <name>A0A423TJ03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001663">
        <property type="protein sequence ID" value="ROT76432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ03"/>
    <dbReference type="OrthoDB" id="10589493at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="53211" checksum="CF25515A47252C16" modified="2019-05-08" version="1">MELLCGVGKPPRRSGWESAWGRASAGKGALNKEDPWGIKRSATMPLSGSGLARGGALRGSSPQAHRRHLLPSTLPSATAARRASRDPYREPLCPTDASRGADEDVVIVDDIGEPGVLRRSQTLPMGAFRKPPTCLSGATAPFQREGGMRRRGSVSREAPGQKGGGLATENETPAAAAHTEQGIENESARIGGDERPITQAPDGGDDDVLPFENPFRRTLTLPPRAMCRRCPTQRTSERRKVSYVHSKTEPDKENVNSTNMVLPGDAPYGTRAAPAWRGKRNSTSSTGSGLSRFTSTTTTDEGVCLYSEGGSVTSSSAYGSVRGGAWSASSVDEGVSVYSAPSVASSADLSSASSLYERAGARPKLRLGPSARGIFHKKASEDDDEKCHRCQREAAGGAPTLRRARSLRSPRHLPVTPTLLRLLQLSSVISQYHNSSFPPPIFLFLLSSSSSPFPPPLLFLLSLSAFSPYPSPVPFLLLSLSFPFPFPPPFTFNPLTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJD5</accession>
    <name>A0A423TJD5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004859</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001645">
        <property type="protein sequence ID" value="ROT76555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJD5"/>
    <dbReference type="OrthoDB" id="10066957at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1820">
        <property type="entry name" value="L1 transposable element, RRM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004244">
        <property type="entry name" value="Transposase_22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11505">
        <property type="entry name" value="L1 TRANSPOSABLE ELEMENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="49206" checksum="171F5BBF560EFA76" modified="2019-05-08" version="1">MRRQTHCSLFLKGACPPPPPRQYHHTSRFATTLPPPDALPHLLLPRLPLRRLSHRIFCRYAMKPPSSSGQRLASPKTIMRSEVISLMEAHKTSLNDTICNLQRALSEATSKLSDVIESLEFTQKELEDSKKEIRKLSDDNAALEQQLRGLSADTAEVKQSLMKATDRADYMEDQSRRNNLRISGIPEERNENWQQSHWKVSQFLRRHFNLTPDLERAHRVGKQKDKPRDIVVKFTRFQDRESVLQDRRRLAGTRVYVNEDLCPATLDIRRSKMDELREARRQGKVAYFNYRTLVVRERRDKDRARDRPARDATQPQATPPSPHTPPPRVASIAEYPVLTSSALQPPASFPPAVPPNTPAVDLNHSTKPLLRLLTPVLPQLPVPPPRHLPATLQPETANSIASRIQATAEARPTPSSPSKAVRMRKPPSYYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLZ9</accession>
    <name>A0A423TLZ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001519">
        <property type="protein sequence ID" value="ROT77473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="673"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="741"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="779"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="819"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="865"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1429" mass="156099" checksum="67164E8C708C3C37" modified="2019-05-08" version="1">MSQSLPAIGGGGGRPCKSDLKVSRGGRGRRRFSPLSLHPGSSSSPEIAFFTLGSLGSSSSPNHPGIVFFTLDRLLHPGITLDSPWDRLLTLDHPGIVFFTLTSWDRLLHPGIVSSGIVFFTLGSPSSPWDRLLHPGIVFTLSVGSSSSPWENHTWITSPGIVFFPWIVSLDLLHPGINLGSSLHPGIAAGSLLHPGILLVGSSSSTDRLFNRDRLLHPGIVSHPGIVSSPWDRILHPGIVFLLGPSPWDRLQRLHPGIVFTHRLFTWDRLLHPGSSSHPGILLLLLTLGSTLDRSSSPWDRSLLQLGVLSPWILLHPGITLGSSSSLESSSTLGLPSPLGSSPSSPWIVSPPWDSSHLGVFLHPGISPWDRLLHPGIVFFTLGSSSSPWDRPSPPWIVSHPSGLFTMGSSSSPGSSSSPRAFFLIVSSSPCSSPWIVFFSPWDRLLHPGIRPSSPWDRLLDRLHPGSSSPWIVFFNPGSSLTLDPLHPGIVFFTLGSPWISLTLDAFFNPGIVFFTLGLPSSPWDRLLHPGIVFFTWIVFFTLGLLGFVFHPGSSSSPWDRLLHPGSSSSHPGILLHLGSSSSPWDGIVFFTLGSSSSPWIVSFTLDRFFTLRLLLHLDRLLHPGSLLHPGIAFFTLDRLLHPGSSSSPWDRLFTLLLHPGIVFFHPGSGSSFFTLGSSGITLGSPGIVFFPGIVFFTLDRLLHPGIVFFTWIDRLLHPGIVFFTLDFFTLGSSSSHLDRLLHPGIVFFTLGSPSPWIVLHPGSSSFTLGSSSSPWDRLLHPGIVFFTLGSSFFTLGSFSSPWDHLDRPGSSSSPWIEIVFFTLGSSLHPGCLLHPGIVTLFHPGIAFFTLGSSSSPWDLLHPGIVFFTLGSSSSPGIVFFTWIVFFTLGSSSSPWDRLLHPGIVFFTLDRLFTLGSSPSPWDRLLHPGIVSFTLGSSSSLGSSLTLGSFFTLGSSSSIVSFTLGSSSSPWDRLLHPGSLHPRDHRLLHPGIVFFTLGSSSSPWESVFFTLDVFFTHGIVFFTLDRPLPPWDRLLHLGLPSSTLILLHPGILLHPGFFFTLGSSSSPWDRLLHPRLLHPGIVFFTLGSSSSPWDRLLHLDRLLLSPWIVTLDRLFTLGSSSPGILLTLTSSPWGPWDRLFTLGCLSPWESSSSIVFFTLDRLPSPWIGIFFTLGSSSSPWDRLLHPGIVFFTLGSSSSPWDRHPGSSSSPWDRLLTLGSSPWIVFSPWDRLLLRFHPGSSPSPGIVFFTPSSSPWIGSSSSPWDRLHPGIVFSPWIVFFTLDRLHPGIVFFTLGSSSSPWDRLLHPGISFLGSSSSPWDRLLHPGIVFFTLIKLTVSTFPSCSVLFPSGRSAYPLTSHLSPVLNPLCLRSQSSPSRALPQKLLPAHTLRLRPPLPPPCPPTASHEIRPFPSLRARGINNLREALARHTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TP48</accession>
    <name>A0A423TP48_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Genetic suppressor element-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003077</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001416">
        <property type="protein sequence ID" value="ROT78219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TP48"/>
    <dbReference type="STRING" id="6689.A0A423TP48"/>
    <dbReference type="OrthoDB" id="6382752at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022207">
        <property type="entry name" value="GSE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12540">
        <property type="entry name" value="DUF3736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Genetic suppressor element-like" evidence="2">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="676" mass="70812" checksum="858E374635A69655" modified="2019-05-08" version="1">MKGPPAPLDDSQEKMQFLGRIGLTTHAHAQEAELSHCERRARVLSALEPSSVPSSPKSTESFSEELVPLLAPGHSLPAVITSPEELCLAHEYPHKARFLHHLGLQPQHSLHRQQEVEAVWQMVVQERLRRYRQESNDPLAVKVCEALEQLLAANIHHQPPQPANSSLSVPLLKVASTPPSPQVRVSQSSTPATTTATTTSAAVAATVASTADTATTTTAATTTAVATTAASSAPIVTSVPPTVVVSSSTAPYSTNTTNFSTKALTASRCSGKAPVKDAVFITAGLPEEDPLLAGLQGVDTVIEHFIKNAQAQGGSNNSALLEHIEEVRRSQLAVCQTAQLVQEQVAQLVASRAQLEAHRSSLHHHLAAITSLIANSTNHSTTTTTAASTTGTGTMPNGTSVFVSAPVTTSTQGVSSSNHSIAQGSSTTSTNTTSTNTSPGHSHPLPLTTTTPTLIGSHPVAAVINRSLQSLVPTASVMSWGGLSSPFLSSTNIAFSLESKDGVFYSQVTNKEGNKDLKTTISSANTSKPNNRITVSHGNAKTSSSNRHSSSKCHKHALTEATNGSPAKFNGIPTNLPKHIFKPLQLSGPNTSANAAKKTTKTVSYTQAPSVTGGLPHPSVALVAPSTTVTSQNGLMPLPLIHNSTSKHGRTNKPQIGFTPYSKTSPTKVPQSWVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TR00</accession>
    <name>A0A423TR00_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spore coat associated protein JA (CotJA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001316">
        <property type="protein sequence ID" value="ROT78887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TR00"/>
    <dbReference type="OrthoDB" id="10506797at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="49753" checksum="16186D7D541A89A7" modified="2019-05-08" version="1">MPPQLMPMPPQLMPLQPMPLQLMPPQLMPLQPMPPQLMPLQLQPMPLQLMPQQLMPPQLMPLQPMQQLMPPQLMPLQPMQLQLMPQQRCTTTDALQPMQLQLMPLQPMTPQLNYNRCHYNRCHHNDATQLMPLQLMPLQLMPLQPMPLQPMPPQSMPLQLMPLQPMSPQPMQLHRMSLQPMQLHRMSLQPMQLHRMSLQPMQLHRMSLQRCGCNDATTSDVTTTMGCHYNRCNYIGTLHLISLQPMPLQLINGFHACTGDSATTGSTTTGDSATTGSTTTGDSATTGSTTTGDSATTGSTTTGDSATTGSTTTGDSATTGSTTTGDSATKLSTTSAPSTTPPQDRIDAEDLLTRYIQFLSDATAPVDDENADQIDSGTVSANSFIEEFDDLIDLIAQTGKRITDGTRALLPRARGDTQQLLDRINNGRIAIREEVERLNPLAENTITLPTLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRC3</accession>
    <name>A0A423TRC3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001304">
        <property type="protein sequence ID" value="ROT79010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRC3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019347113" evidence="1">
        <location>
            <begin position="35"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="46063" checksum="C56065CE89C30382" modified="2019-05-08" version="1">MPTTGFANHWFMPTTGLCQPLVLPIGLCQPLVLCQPLLVLPTTGYANHHWFANHWLCHPTTGYANHWFCQPLVLPTTGFANHWFCQPLVLPTTGYANHWFLQPLVFCQPLVLPTLVLPTTGQGFANAIVMPSTGFANHWLCQPLVLPTTGYANHWFCQPLVYANHWLCQPLVLPTTGYANECQPLVLPTTGYANHWFLPNQNHWLCQPLVLPTTGYANYWFCQPLVMPTTGYANHWFCLLVLPTTGFANHWFCQPLVLPTTGFWFANCLVYPTTANHWFATTAMVMPTRGFANHWFFSNLVLPTLVFANWFCQLVIANTGFQTTGLPTTGVANHWFCQPLVLPTTGFANHWFCQPLVMPAPVFSNHCQPLVLPTTGFANRWFNLITCRKCYVFIVKVLVASESDYSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT40</accession>
    <name>A0A423TT40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001212">
        <property type="protein sequence ID" value="ROT79636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT40"/>
    <dbReference type="STRING" id="6689.A0A423TT40"/>
    <dbReference type="OrthoDB" id="10257076at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="60"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="421" mass="47501" checksum="CEFB4CC46B0DDA79" modified="2019-05-08" version="1">MPLPSLLLSALFLYSLFIILLRVSSALRSSLHSFLSLHTLFSLLFSLFPSFLFHSFLPLPNRTALHFAARNGHLSVVQFLAENGGDLNARDRFVLTLPYFLLTMMPIPLFILPFASISILIPTPINTTVDTSFFLPQTGPPFTSLPGTDTFLSSNSWRRTAATSTPETLVLTLPYFLLTMMPIPLFILPFASISILIPTTHQHDDETALHFAARNGHLSVVQFLAENGGDLNARDCDVSHPLPPLSPLHLFCLSLLSALIFLPYIFSLSSFSLSFLCFLFLPSSLYSFTFFLLSLFFLFFLHQSLSLFPFFLFFFLFLTPFFSYSFPHFLLSYFLLFFFNPFSSFFSVSSALRSFLHSFIPLHSLLPTVILSLSLLFFSIPSSSFLVLTLPYFLLTMMPIPFSSSLSLPFPPHSHTHQHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT91</accession>
    <name>A0A423TT91_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001205">
        <property type="protein sequence ID" value="ROT79677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT91"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1162"/>
            <end position="1182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1185" mass="130575" checksum="E2DA0E811E8DD124" modified="2019-05-08" version="1">MQTINPSPIAFFLPSPFAFHLPSPIPFFLPFPIAFLLPQSHSSFPNRILPSFPFAFIFLRHSSFPNRIPPSFSNRIPPSFSNRINPSFPNPIPPSFPNRTPPSFPNRINPSPIAFLLPSPIAFAFLLFPNRIPPFFPNRIPLLPQSHSSFLPNRIPPSFPNRILLPSPIAFLNRIPSFAFLLPSPIACIIASSNRIPSPIRIPPSFPNRILHPSPIPSPIAFLLPSPILLLPIAFPSPIAFLLLPQSHPPPSQINPGKSPPLQNRIPSSPIAFLSSNCLPPSSQSRILLPQLHSSSFPNRIPPSFPNRIPPSFPNRIPLPSPIAFLLLPNRIPPSFPNRIPPSFPNRINPSSPRIPPSFPNRIPPSFPNRIPPSSPIAFLLPSQSHSSFLSPIAFPSFLPQIAFLLPSSHSSFLPQSHSSFLPNRHYSSFLNCPLPSPIAFLLPSPIASISPSFPNRIPPSFPNPNSSFPMHSSFFPNRIPPSFPNRIPPSSQSHPSFPISLPSPIAFLNRHSSFLPQSHSSFLPQSHSSFLPQSHFLLPSPIAFLLPSQSHSSFLPRIQSHSSFLPRIPPSFPNRIPPSFPSPNRIPASFPIHPQSHSSFLPNPIPPSFPIAFLLPSPIAFLLPPQSHSSLPRPQSQSHSSFLPQSHSSFLPQFASSFLPNRIPPSFPIAFLLPSPIAFLFLPQSHSSFLPQSHSSFFPNRSSFFPNRIPPSFPIAFLLPSPIAFLLPSPIAFLLPSPIAKFPPSFPIAFLLSSPSQIAFLPNAFLPQSHFLPSPIIPSPSHSSFLPQSHSSFLPQSIPPSFLAFLFLPNRIPPSKSPFLLPSPIAFLLPSPIHSSFLPQSQFLLPPQSHSSFLPQSHSPFLPQSHSSFPIDSSFLPQSHSSFFPNRILPSNPFNSSFLPNRIPPSFPIAFLLLPNRIPPSFPIAFLLPNRIPPSFPNRIPPSFPNRIPPFPNRIPPSSPNRIPPSFQSHSSFLPNRIPFLPQSHSSFLPPIAFLLPPNHSSSFPNRIPPSFPNRIPPPSSHSSSFPIAFLLPIAFLLPSQSHSSFLPNRIPPSFPNRIPPSFPNRIPPSFHSNRIPSFPIAFQSHSSFLPQSHSSFLPNRILLPSPIAFLLPSQSHSFLPIASLPSPIAFLLLSPIAFLLPSPIAFLLLSPIALLLPSPITFLLPSPIAFLLPLPILSILSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVI0</accession>
    <name>A0A423TVI0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative synapsin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_000801</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Synapse</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synapsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001119">
        <property type="protein sequence ID" value="ROT80465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVI0"/>
    <dbReference type="STRING" id="6689.A0A423TVI0"/>
    <dbReference type="OrthoDB" id="10249572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030672">
        <property type="term" value="C:synaptic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007269">
        <property type="term" value="P:neurotransmitter secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001359">
        <property type="entry name" value="Synapsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020898">
        <property type="entry name" value="Synapsin_ATP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10841">
        <property type="entry name" value="SYNAPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10841:SF17">
        <property type="entry name" value="SYNAPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02750">
        <property type="entry name" value="Synapsin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01368">
        <property type="entry name" value="SYNAPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0770">Synapse</keyword>
    <feature type="domain" description="Synapsin ATP-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT80465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="235" mass="25084" checksum="108928D4161735C1" modified="2019-05-08" version="1" fragment="single">LGPRYPCVFKVGHAHGGLGKVRVESNADFQDMASVVAVANTYCTTEPYIDAKFDIHIQKVGGMYKCFQRKSISGNWKTNTGSAMLEQASMTERYKAWVDEGVTRPGPAELTRGSSRQSLSGTMSSRGGSPTEDTSRLIMSETPIPGGSPSQQRRDSQAGSPTASQSSSISGFSSASGTRRQVDEVSQSSQQSAGQKPSLFGRQTSVTANEAATGDDTEDTMKNLRKTFAGIFGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVL8</accession>
    <name>A0A423TVL8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CDGSH iron-sulfur domain-containing protein 2 homologue</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the CISD protein family. CISD2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVL8"/>
    <dbReference type="STRING" id="6689.A0A423TVL8"/>
    <dbReference type="OrthoDB" id="449252at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.90:FF:000001">
        <property type="entry name" value="CDGSH iron-sulfur domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045131">
        <property type="entry name" value="CISD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680:SF5">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="7">
        <location>
            <begin position="111"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU369084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="163" mass="18045" checksum="82183767BACA60BC" modified="2019-05-08" version="1">MRDDLGSSILPCRLTLAAWRRRSEDPRGERKRPKTLTQSGQSVISWANTCISSHQTFAKIMDFYKNLTVSDWASLIPFGIACAAVGFGVKTVVDKQIGGPCNPKIRKGESKVVDTVDIEELGNKAVFCRCWRSSKFPYCDGTHNQHNVACGDNVGPLIVKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWP3</accession>
    <name>A0A423TWP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Putative histone-lysine N-methyltransferase 2C-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_000393</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001055">
        <property type="protein sequence ID" value="ROT80879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TWP3"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044666">
        <property type="term" value="C:MLL3/4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042800">
        <property type="term" value="F:histone H3K4 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19171">
        <property type="entry name" value="SET_KMT2C_2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.360:FF:000001">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000002">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45888">
        <property type="entry name" value="HL01030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45888:SF6">
        <property type="entry name" value="HL01030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00542">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00541">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 18" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="17">
        <location>
            <begin position="2086"/>
            <end position="2194"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="15">
        <location>
            <begin position="2462"/>
            <end position="2578"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="16">
        <location>
            <begin position="2585"/>
            <end position="2601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="44"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="224"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="305"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="403"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1065"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1528"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1704"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2015"/>
            <end position="2034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="548"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="1069"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="1105"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1530"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1557"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1709"/>
            <end position="1722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT80879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2601" mass="281251" checksum="7D53C218B280E60E" modified="2019-05-08" version="1">MEFEKLKADVLSVGNTTVGLPSIAGGQVIGTNASVRQPFQRVVGQPPPQGAGQAMYQSPCPAQPATRPVRPQGDPGMHPALLQAVGSRGTVPSSPGTVNIKTLPPPPQPPDNPQTEAERHQQLQYENWLTQQHSLIASQQRHYDTEITKLRKQRKSLNSRQRTLKKNGQELSEHDAAELARVQRDASTIQRHLEQCRKSARQHAMIVQEYNNKKRQRQAHMMNTQSGVIGPGNPGQLMSGASPMGPTGSSPMHSTPQSPLMSPSPSSQPGMGLSPMVPSPHTPAASPNPAIVPQHSPHAMVVPVPHPSPGESPFSPQTRMPSPGGGYPDQGPRAPYPGPQGMTHHMMGPQMRVRMPVHSPGNQTVQPGQMSPHMMGVRPAYPQPGVMMSQGQAPMMMRHQYPQGVMPHRRPSGSGPVPSPGSGPSPSPGGPVPSPIGGGMAMKPSPVQSGLKSPVPLASPSPGGPVPSPLSGSMAMKPSPVHSGLRSPVPLASPQMRPHSVENPSTPLTPRSVGAGDMGGAPQTPHSDMGGASGSNSQVNSPHPSVPTPTSDAVPSPVPSSTPSMVQGGQRVGGGGGNANNPNNPAPCPPYMRRFGYFKLGLRGGGFVKSRWGHFKLGLKGGMPHGDVENNVVQATSNSGLSTTLPTTTTTIAHTSSEPSTVRAASTPVASLKNEPEGDEGQEGLAHVLSESGPIKGPIVRMPMIGGGGQRVSQSAYVSAGSSVTMTPQLSANANKVLVPEPLKSEIPPSSRHQAVIGIPGGGAIFSQNNMYPTHTVAPGIRLPTAVSTVNYPSTLPNQNQVSATSTLASVLSSSSGSSSSAINSSLVPPPIMSVTSSAETLPSLNIQSTSQPSDDVQTLSNVVSINNQVSGITSGLTNYASTANVPLNSSATTNTTPSLSRPLVSVPVQQIGIQQRPMLQTLTTTVATPQVRTLPSIGNLQAGTRQFKTLIRASVGQHPGVIQTGQDQAGNQIVTQQQVLQHTLPQQAGAPPTLGQQTWVQTSGGPIPHSGVVVQGGVPQTVGVRMVQQPMMVQQTLVRSGNMMVRPGTTGQGGVRMMMIHGVQPVRTPSPPVNRPAMMPPPAAKSPAGHSASPIPRVSPAPSPLSNHPSPHSPQVKGQSPLMSSPAPSPHGPHTNVAVGMIKREPDDEHTNVVLPPHHTIAGSVTQQQAGTVHMTISGVQPHTTANVHVVNPQHASTIAGTIKTEGVSEGMNKDSSNALLKQLLENTGCANSMSQPSSSPLVLFRSPQGTVPVPSSNLTHIASQIPNPTPIVVSRSSVPATLPASHPTVLQATTSATMVPQNATVQQPQQQHTVASGSLPQQLGPNPQMIQRSVVVSSGPHPPQGPVTHTVVMGQQHQLIAHSDGHGNLTHTVARPGVPYTGQHHVVDPHNAGPQPSSQHIGVRQVTTHHLSHPGMNSSAGHHVIQGQPPHQTVTVSHPNHPMGHPLPHSNPQMVVHPGMRPTHPGQHPMVNAHAPGTHIVTGQRPPLATAVLNATPTPASLADRVNSNPALKTEMRVMIPETVLGTGASTGEHTPEMTTPNEGSDSLDHEEKKARKRSQQARRKSQSKDTKVQPAKRARQGSRVEEDYDAYIENVMQQLRGMPPLTIMEPEVPKNFNLCPMFGSGDLSKLGRRDYNHRQGLLEGKEGHLTVKNITDYYSTQPFGDKPPMVTPAKTNPTQRGFYIHEFTPPKIGLPLDEYQEGETVVASSNRPTPAQTPTRDADSPDTVLSSSSPECILPESPLPFKGLRLVDMDEDHQDDQRDRSLSPAIPLLVPTPIRPGQLPFMPQIKDGKDVPELDKENIGSLASITMKSRLGQSPALPLKDMGNVSVTLTLSSQAGEDVSGILRSLANLLNIPPPSSYQMADRIEPPKLPRVYRHKHPKDGVEQLVDIQSILNGQARFCRHCDVIILKDILCKKVSELPFLNKSDYESVDEVTFCSQQCYIQFAVSHRVVVEDRGKLEGSSRFAKVKDSCGDNTKDPSILSDDALLDWSKEEGMDEVLKVPQLEDSLHSRPNKHKLEEDQEQYPRQADGKRFRGHKYKCWTPNALTLPEKYEKPTPKEMTDLLFRMGITYRKPRLKDDSRKCTLCGLYGDYVADGPSRLLNFDVDKWVHLNCALWADEVYETMNGALMNVEASLKKVANYVCEHCEQAGASVKCFKVRCSKVYHLNCAVKEGCTFYKNKTVFCQEHINKGEKDNELSTLAVFRRVFIDRDDNRQVASVMHHADLSYVLRIGSLILIAIGQLFPHQLQAFHTPYCIYPVGYQVIRYYWSMRRLHKRCAYECSIHDNSGQPEFRITVKEEGYDDHTFISCSPKGVWNKVLEPLAELRQKADVVRLFPQYINGEDLFGLTEPAIVRILESLPGIDTLADYNFKYGRNPLFELPLAVNPTGCARSEPFNKMHLKRYHGMRTSVGSVRSSSNCRNAASVANLTMTFDPYSKLHVHSRSSQYKRMKNEWRSVVYLARSKIQGLGLYAARDIEKNTMIIEYIGEIIRSELAEVREKRYEAQNRGIYMFRLDDQRVVDATVTGGLARYVNHSCGPNCYTETIEVERDLKILIISNRKILRGEELAYDYKFDEEEDHKIPCLCGAENCRKWMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYE0</accession>
    <name>A0A423TYE0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hamartin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000968">
        <property type="protein sequence ID" value="ROT81475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYE0"/>
    <dbReference type="STRING" id="6689.A0A423TYE0"/>
    <dbReference type="OrthoDB" id="6022054at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="502" mass="56636" checksum="913A195C98BE42EF" modified="2019-05-08" version="1">MEEVKDQNVGDVLALLESPQEDVVQEVRLLLKETLTTVREGWLMTGLLDYFFTSNSGRLLDILLGVSEPHDRHLLDRLAEGLKGPDRFRYTCLLLYAARRQPTTTWLRKFVNHGAMRELLNCLHNEDDVPVTVSGIMVLVMLLPALPLEMGHSHLTNILDIFCRLLRWSPKREQDEGFQPFLQVAVYSLFHRLYALYPCHFLTYLRNNFSKPNSSNCFFTTLKPMMEKVRLHPLLITETKDSELTRNRWIGLETHQLILECAKLCLDPIEATCEESCGSFFTMNGGSDIPLDPQPVPTNWMLSAVENNFWSPSLAQSSPAPLQTPRGSVPQTPVYPILTPNQRGKVAESPPEAAIEATPETTPFTSPIKMEPNTLVTRRPLSGRRALTLNTGGAPEPVGQPADSEANSSPMSPLKKDQAPFRFPENQGQDFFLRAERSTLLQTKLQQIQRERQINQIENLFSQYTENKSETDSKNEGDVVDGRDTKEGNSLVPRKAVGIGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYE9</accession>
    <name>A0A423TYE9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000966">
        <property type="protein sequence ID" value="ROT81487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYE9"/>
    <dbReference type="OrthoDB" id="6075074at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="40713" checksum="84C83CD206A9BB7C" modified="2019-05-08" version="1">MSLLPPSTALIPLLFPQFSLPQPFLSLPNTFSLSLPSPPYTTHSPSPSTHSPSPLSLHPLSSSLSLSLSHSLSLSLTHPPLPLPLPPPTLDPPSPSLFNFAPPHPYCHHPYFHSPPPPHPPPLPYLPSPHSPPTSPPSPPPPTFTSPPPHSTPIHLPTLPTPHLLSASLPPPIHLPPPTSLPLLPHPLTPHSPLPSPLPPPPHSPPIHLPHITSLYTHPLPTPDPYPPTPPSSSAPFVRSFEWRTKRVGRGVVGSGLCANDFLLRGGARLAESLLRSVGSPALLCLFRRLLEFILQLASSNNKFANNIEPQPQTTSHNPSSLPCRFVGDGRVGSAPMADEGHAQAPPTSSTIVHYEQLMILKTTDLAGRLVGCTFSQRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZ37</accession>
    <name>A0A423TZ37_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000928">
        <property type="protein sequence ID" value="ROT81725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZ37"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="48834" checksum="86C49F003A3EAA1D" modified="2019-05-08" version="1">MKTSRAEKYLRFHRNHLDTLIDRSDTSQNSCISVLSGSYFIGRIDGIGFFSFYLIYFLSLFCFLVSIFFLFRPHWFTIFSSLFLSSPVPVFPLFIYPFLFPPFLTPLSSSSLLLLFCIFFFPFPSSSLLYSPSPHASSPSFYPSFPPPLFLQPLPPTASPFPQSGCPLSLSLHSLSPPSLYFLYPFPSILCITFTLSPSPAITSSLHPLLSLTPSFLHPLPTLSPSFLHPFPTLSPSFPHPLTSLTSPSSLSLPSPSPSHPLSLLSPSPPHPLSLLSPPPPSPSTPNSPPPPAQPLAARRVRADNRFISKSRLRTRRRDPKSLLTAIQPSAQTRLFTLRLRCLPECSVSSICVAGLFTWGVPRAWIWCCVDYPGVPTKANSQLLHPRLPLPDRLGPRPPAHGQPGRLSDALSDVEALRPPEPASARVQHLINVSTTNHRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0N7</accession>
    <name>A0A423U0N7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_024553</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000851">
        <property type="protein sequence ID" value="ROT82261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0N7"/>
    <dbReference type="OrthoDB" id="6373363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019452623" evidence="14">
        <location>
            <begin position="32"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="15">
        <location>
            <begin position="278"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT82261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="677" mass="74716" checksum="4D576A70A7BA77B3" modified="2019-05-08" version="1">MGLPSPPRCVLIAALLTSFGWWLVPVAGAEASCGQLRAAVGLKASLDNEILTARQLAEDYLSECQLVMISTSQRSSLFEQVVRTTARRQNGVGVVSLEIGPRQDLPREILPSVWRDAGANCRVLFLEDGGDTSSILEFLEASELSRHPDVSVVFVGTAAGMVLYHRVFRNTVHALYLSLSNVTLQDARPLPREDDLGGGCGGRRGSARLYQRCLYCLEGEESVRPLQEWGRLAQRPQPANPFPDQFKDFFGHRFRVVAMRTLPWMDYEGGGGGWAGGPLTPRDSLNARMLRAMADHSNFTYEVREPPEGRFGLYLGNGTWTGIVGALQQDVADFSTEIGLLPPRLQAMEPSFIYARDRIVIASPKPGPLPQHLAISRPFAGTVWLLILAGVLVSDVVVWVLLRLVAWVTGAGGADVGGSLLYSWALLMENPPPPPSPSSTIRVTVGFLLLYTLVINSAYRSSLIAHLTVQGFPPPIDSFDDLLEQGGWTWGSQPLFGTFFVFFNQSSDPVVQRIYAGMEVASMDEHLAKIPKKRHAFIDFKYNLRTQVAARLTDALGYTPVHLSRSEYPSYVGDIWGFRKGAPFRHHICMLQQRLIEAGLIDFWLRDVIRAYADRHRAKEDAAVGATERLSQDGDGIVVLNLSHLQGAFYLLLLGHGAALILLLLEVFVDRVRGESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0Y7</accession>
    <name>A0A423U0Y7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dedicator of cytokinesis protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the DOCK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000837">
        <property type="protein sequence ID" value="ROT82349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0Y7"/>
    <dbReference type="STRING" id="6689.A0A423U0Y7"/>
    <dbReference type="OrthoDB" id="47328at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.740:FF:000002">
        <property type="entry name" value="Dedicator of cytokinesis protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.410:FF:000002">
        <property type="entry name" value="Dedicator of cytokinesis protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026791">
        <property type="entry name" value="DOCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043161">
        <property type="entry name" value="DOCK_C_lobe_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043162">
        <property type="entry name" value="DOCK_C_lobe_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027357">
        <property type="entry name" value="DOCKER_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046769">
        <property type="entry name" value="DOCKER_Lobe_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046770">
        <property type="entry name" value="DOCKER_Lobe_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046773">
        <property type="entry name" value="DOCKER_Lobe_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317">
        <property type="entry name" value="DEDICATOR OF CYTOKINESIS DOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23317:SF76">
        <property type="entry name" value="LD20667P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06920">
        <property type="entry name" value="DHR-2_Lobe_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20422">
        <property type="entry name" value="DHR-2_Lobe_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20421">
        <property type="entry name" value="DHR-2_Lobe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51651">
        <property type="entry name" value="DOCKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOCKER" evidence="4">
        <location>
            <begin position="408"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="852"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="852"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="883" mass="99956" checksum="CA5B6A66E8C135B2" modified="2019-05-08" version="1">MYLPVVSNDGRKQHILTTTQGASYLVYGEEPLEVANAATASQPISATANVTHHHHPGVGRTTSEDSTTQTINEGRPPLPPVSHSQEHFGVVQNSSDFVQLAHSPTKICDLHQQSHGKKISLRGGGPSLRCKADMKSRLEEAIMGQNSARSEMMLRRRERNPPSPSGTGERLRWRKETFPWRHQQQDTERSTHQELEQESQVEGHLASEANMIILDTLENIVQVVTNADHLQGLLSVVFRVLLHALASNQSTTSLTNMFNTQRALVAKFPGLLFDEETEQCADLCLQLLKHCSSCICTIRSHAAASLYLLMRHNFEIGNNFARVKMQVTMSLSSLVGTSQTFNEAYLRRSLKTILTYAEEDADLQDTSFPEQVRDLVFNLHMILSDTVKMKEYQEDPEMLLDLMYRIARGYQNSPDLRLTWLASMAQKHSERVQHAEAAMCLIHSAALVSEYLYMLEDCPHLPTGAVTFCKLSPNVLEESAVSDDVLSPDEEGICTGKYFTENGLVGLLEQASSSLQQAGMFECLNEVYKILTPIAEKNRDWKKLINIYSKLHDAFSKIDALEGRRIFGTYFRVGFYGSKFGDLDGEEFIYKEPMLTKLPEISHRLEAFYSDRFGAENILMIKDSNTVDATKLDSDKACIQITYVEPYFDEYEYRDRVTSFEKNYNIKRFIFSTPFTPDGRAHGELHEQYKRKTILTTQHMFPYVKTRIQVVDRMSWVLTPIEVAIEDIQKKTKELSAAINQDPPDHKILQMVLQGCIGTTVNQGPMEVAHIFLSDLVDSRKPPNRLQNKLRLCFKDFSKKCQDALRRNKTLIGSDMREYHRELERNYNKFIEGLSPMITVNHLTRQMRVTSWHHSSGSTSSVDTLVSGGSADSDPGLASGTEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1C7</accession>
    <name>A0A423U1C7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000817">
        <property type="protein sequence ID" value="ROT82499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1C7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="47750" checksum="7CECA0F1CA75CD5A" modified="2019-05-08" version="1">MQGVTSFGMEEGHPFSMSRHNSPCSLSLSLSPPSLLLLFPLSLLHLPFIFFFLILLFVFLIRLFHVIYLYLLLPLLFLFLLLFLPYLLLPPYSPPFLFLFPPLFPYLLLLLFPFLFIFPLFPPLFLYPLLLLFLFSSRFPYLLLLLFPFLFLFPLFLTFLPYLLLLLFPFLFLFPLFPPFFPYSSSSSSLFSSYFHYLLLSSPISSSSSSPFSSYFLYFLLSSPISFSSHFPYFLLYSLISSYFPYFLFSSPISSSPSLFFSYFPYSLLSSPISLSSSSPFSFLISSSSSSPSSSYFPHFSPLLLSRPPTLFPFLFLFSLFPILFPYIFLLFPFIFLFPLFPPLFPCLLLLLFPLSLPISPISSFLLLSPPPPFPPSLPIPPLSPLPKEQTLYPLLFINLSFLSFFLALFSLTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3D8</accession>
    <name>A0A423U3D8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000718">
        <property type="protein sequence ID" value="ROT83210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3D8"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019046121" description="Chitin-binding type-2 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="4">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="5">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24547" checksum="667ABF2E6B1E29DB" modified="2019-05-08" version="1">MAGVKCLLVLAALALASASARPSTECSCDGCLYPSMSDCSAYWECQGGRAVEHRCGAGYRFNPDTSRCEHAIRVECSTSVRLMGDFASETCVDRRVSCPVYAAAGGCECRGDDCDWPAYVVSSCPKSCDMCGAQSKFKPWWIDSSEDSSEEGGWKPWWKDSSEEGGWKPWWKDSSEENGSSEGNGSGENGSSEETEAPPPPTAAPTTRPPPPTAAPTTRPPPTHSRPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3P2</accession>
    <name>A0A423U3P2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023493</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000700">
        <property type="protein sequence ID" value="ROT83325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3P2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="15">
        <location>
            <begin position="255"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="14">
        <location>
            <begin position="383"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF10613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="681" mass="75616" checksum="05D278609E1CB7F7" modified="2019-05-08" version="1">MAMQFTLRNIKHILILTILVENPFLEAQAAFRSKRDLVTRPALSRSPGHPGDRGTELASELVARTVNDYLSSCHLVLMTSRRSDLLESLLRKAESIVENPHPRRGLRMGTVAVQVESAMAAAPSSRTALLQGLWGAADVSCRAIVVDLMDGNDRSVFRFLEAGLSERPKIRVLMLGPEKGAASSLLHPALKNSISAVYFSVVGTNSSWIEVVRRCLYCRGGEAGVEPLGPWHSREAMPTEEALFPDEFRNFYGHRFRVVTLRYFPFIEYTRESDAPGSKVSPRDCLDLRILSSLASRNNFTFEIREPLDGEWGVPRADTGNWSGSVGTLQHDLADFSMNLTPTRERFRVIQFSRVYVSDPYVLVSAKPGILPPIFAIVRPFTADVWSSVAGCTLLTGVVLWVLMWAWRRVFGGRGFKLSDALMYPCSLLLEDPPYEPPSASSARVLLGWWLVACVVIGTAYRSSLVAFLTVEGKTPPINSFDDLVKRPGWRWGMKPSTGSFFAYFNSSKDPTTQLVNKGMEVDDLEGQMKKVMAGGYSFVSTKLYSRSVIASQYTDSRGYTPFYTGTREYHHPPGNSWGVRRGGPFLDYLSTKKLQLIEAGLINYWLDDVIRTNVRETRAKGKQQTIAAQDQGRVVLGSHHAGRLLPSSRHSVALCTLLLEALTEAPFAGLLKGCQETFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3S3</accession>
    <name>A0A423U3S3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000697">
        <property type="protein sequence ID" value="ROT83357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3S3"/>
    <dbReference type="OrthoDB" id="436496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043020">
        <property type="term" value="C:NADPH oxidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042554">
        <property type="term" value="P:superoxide anion generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF153">
        <property type="entry name" value="SUPEROXIDE-GENERATING NADPH OXIDASE HEAVY CHAIN SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="240"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="755" mass="83982" checksum="1ABC889547287EA5" modified="2019-05-08" version="1">MVLLLAALCLTSMRCFRRLCYDGFYYTHRLGIVFLVLLLVHPLSGVLKEQKNLHGHIPGCQMYKETLRREEAEEIGFPEPEPDEVSYPEHNDIGYPEPYGDHYTASDEVGFPEPEEEPDEESYHVSNAMSFGSEEEVGFPEPDVAGYSGPEEIGYPEPNVDYPAAGVGFPEPDVGDTGSEDIGSPKVSGGKGRSGKYHRTRKKRRKCHRPPVFGAIHSKTWIWVGVALLVWRRTGLVRCGGGGWSGVVEAVHHPCDVVELTLRLPGFSCLPGQFVMLQCPQVSNFEWHPFTVTKPPTTPQPPDLPVILSSRFPSLALCLASAPQLFSQLLVPFPAPYPTPSPYCPFSPLALALTPAPTPSEFSPGTFTVFMRARGDWSKSVAALLPSKSSQVDDPSQRPPYGPLALSSRRPHTKPNVVQASYLSSKGANGRGPFSPQNGQPRLSGRARDEAKVYSFLPGENASFNLWREHGTSQSPVYTDAQDNERSCSQSPLMKNFSSSQSCIKVHSQYNHLSPVLTHGKLSQSHADNHIDELENIYSNSNKNTLLQLDKHVQKIQIENEDSHQTAEHQVVHMAPDACARLYVDGPFSSPSEDMIRYPVVVGIAGGVGITPLAATLTHILHHPASWPKRVHMIWVMRDARLILTMAHLLSSLLHQSWQDCNEDRLEFCFHVTTPISHEALQELFGDRHPTLIPRIKQGRPQWKNLFHQYSQAYKKTKVGVFACGPKKLCQEVKRLCLRSVTQGAPFAYHQESFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7J6</accession>
    <name>A0A423U7J6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_022143</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000514">
        <property type="protein sequence ID" value="ROT84674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7J6"/>
    <dbReference type="OrthoDB" id="6366971at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051967">
        <property type="entry name" value="Krueppel_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45925">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45925:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13465">
        <property type="entry name" value="zf-H2C2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT84674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="135" mass="15642" checksum="EEDB455D2E8D744B" modified="2019-05-08" version="1">MRMLLGAGVTDGVYFLSQMAMNDLLLSGLALPHAQPQQKQSKEAQCYICGHKFRWDWLLRRHMRTHTGEKPFSCPYCQYRANRKEMIRSHIFHRHLKPQAGLQQQLQSAQQQLQPQQQPQAQSQSSQQSQPPQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7J8</accession>
    <name>A0A423U7J8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000509">
        <property type="protein sequence ID" value="ROT84700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7J8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="700" mass="76578" checksum="8F4986A161CD251E" modified="2019-05-08" version="1">MKADTRERESAVLEDEHQHGFPMTSIFCAFLFFSFFLLLLLISLSPSFISFSSLPLLSLSPLLPFLSLLLSFLLFFLILHCFSPSSLLLLFFSLSFSFYSYFLSSLSLISFFLSSLISFSPQCIDFSPSSFVSLSPSLVSLPPRLISFPPSSLISFSHSPLISFPPPFIYFPYYTLNITLIFFFFLSSSPVPFLSLFPRFFTFINLFLDKFIFLISVYRLLLFYLSLPFLSHIVSLFTLSLPSLLSFPSLLFFPFLFFSSPSFPLHPPSPPDIPSSHILSPLIPLSSPTHPSPPPPSLLTHSLSPLHLPLSYHSTLPLSSFHPPSLLIPPPSLLIPLPLFSFHLPLSYHSTLLSPHSTLSPHSTSLSPHSTLPLPIPLPPSSLHLPLSSFHLPLSSFHLSLSSHPSPHPPPLLLISHSPSLLIPPSLSPHSTLSLPFHLPLSPFHLPLSPSPPPPLSPFTLPLSSFHPPLSPHSTLPLSHSTSPLSHSTPPLSSFHLPSSYLSSFHLPLSSFHPPLSSFPPSLFSHSTSLLSSFHLPLSPFHLPLSSFHPPLSPHPLPLLSPHSTLPSPPHVHLLSPTPPPSLLIPPPSLHSPLSPFHLPSLPPPSHLPSPSLPIPPPSHLLLPLSSFHPPSLPSTSLSSPSPSHLIPPLPLSPFHPPSLPIPLPLSPFHPPSLLIPPLLPSLLIPPPSHLLLPLSPFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LR11</accession>
    <name>A0A3R7LR11_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003822">
        <property type="protein sequence ID" value="ROT62123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LR11"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="505" mass="54284" checksum="46FAD9BF26CE7C93" modified="2019-04-10" version="1">MKTHPPTRRTISPKQRDCILDLKFSKVSPLPASSPSPPLPLSLIPFLSSLPSSPLLSNLNIPSLPPPSLSHFPFLSPSSLSSPPLFPSHSPSPLLLYSPPCLSPPFPLSPLASLSPSSLTPTLIHALLRLLFPSPTRPTSTLIHPPAPLLLSLPLAFSTNPSFTPSLSHFPLLSPPFPHPPPSSISFTLNPPFPLTALSSPTPLLLPHSPHPFPYPHRFSSLYSSSRLPSFRLSPSHSLPSTPHSPPPFPSLTRCSLPLSLFPPSLLPLPPPSPLPFAFPSTLFTPPPLPLPPTLSISLPSKPIHRLPSSSVPLSYLPSPASASSPRSLTLHPSSSFPYLNPPILPPPLPSPTPFFYPHSPPSFPSSPALLPLYPPSPSHSFLSHSSSPLSFLLNPHHPLPSLTRSTSLYPIHPPPLPLLPLSHSPSFYLNSPSPPPSLTHSPSLYPLQHLPSPLPLPLPPLLPSFYLIPLPPPLLQLPHFPFLLNPHSPSSLPLPPLPHLPSPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LR67</accession>
    <name>A0A3R7LR67_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_021695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004592">
        <property type="protein sequence ID" value="ROT60730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LR67"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT60730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="45549" checksum="7C73805EC57E18DF" modified="2019-04-10" version="1">MSHFLNFVKMDILNLREESVIVSVERRCCSPSPSRHSLPPPLPHSSLPHPLLPSLASRPLHFRSLHSPSLFLIFTLSPTSLFPFLPPLSHSLSPYFSNTYPSLFTLPISNSPSYFTVFSSHPHQLFSLSLQPPLSLPLTFFHLSRSLSTFLLPLSLSPPLSRPHLPPLLSHLPSPPSLPPHLLPLPLPFLLSLSYTLFPYFLIHPVLFPHHSSFFIHSSLFPFFHAYPFPLLPLSPLLQSLSFCISSSIPPISLFLISSHLPSPPLPQVYSLSLFYSPFGPPSRSLLHLTSPSPSLPSLFFPFLPIQRLILFPFTLLPSSRTLPSPILPPPFLFPLPSPSPPKSSLLSPPSFPPSRASFPSPPSPCLPSLPTHPYPLFSSYPYPCPPLLLLSPTPFSPLALPMSHSRSSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRM2</accession>
    <name>A0A3R7LRM2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003623">
        <property type="protein sequence ID" value="ROT62566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRM2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="42224" checksum="828026F7F409063B" modified="2019-04-10" version="1">MTKVKINVHGGPSPSRRNTLAQALFEAEISLLRYYPTHDGYVALIEDNSQAEKHFSHQVTTKLEKLGFSPVLPLDMRAKLTLVFKKLDRQVVNETSDDITNEIMASAPHAKVENIHIMQALYMIKARFADHASANKIKEEGIFLFKLYVAPWQIEFERFTPVRQCMNCYAYGHLKTNCKDEKKSLCSESVAQKAAQATVQATTNAWRPLINQVRQDIKENNIPKKDPTMHLALPNDLSRDILGTCQGGPKEEQPPRPRSKRSRLLGDPEGGPTSSPSAPARKPSEAALHIQALDTQVEQISPYTPTTPATPTPAPDTSVRPKQQRATAIPASSKTHTPAPPKAVDQAPSAELATPGPAETSSPTIPTAPLWGRIVWRGLWME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTA3</accession>
    <name>A0A3R7LTA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003730">
        <property type="protein sequence ID" value="ROT62315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTA3"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41996" checksum="1A5CDD31FF20FEBE" modified="2019-04-10" version="1">MQSCSEFADISEASLCRRSSIAMTETSGNLSASRDFGTSSQDSLLSAIPEDENDSETVKVLHLEDSQQAVDILDLKDSEETVENLELKNSQESAAIVEVKGSEAIEILDLTDSQEDVDILEVKGSALEIPDLQDSQEYVNILDQKDSEAAAELLDLKVSEEAVEILHLQNSQESVDILDGKDSQETVVEGQNESEAQNSKCSTIFDVTEDAASVQESPKSMDEELAQFSWQNNYPEIVPRKEAVDSVGQLNLEETTETKESNPIDTITSSTTIAKESAEAVESLKGTRRIHRDSPEELLLITKRGNFFQDSFFLDAHRDFSAALRQVLGRCNQDNFEDDTDLRHTDILERYRQLRSRDLREENQAAIVTSDKVLYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWK1</accession>
    <name>A0A3R7LWK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002936">
        <property type="protein sequence ID" value="ROT66426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWK1"/>
    <dbReference type="OrthoDB" id="10310092at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="365" mass="39895" checksum="2A0CA5AB03D5F084" modified="2019-04-10" version="1">MSLRSAVSCPKGRRGGNIEHAAGVTQAAAILRGTHLVARHISPAATSSMCGSRAGCVVVAKPHDRYQPRRILRDHLNDPSAIANVLRYATLPVMGRLDPERYAALTQSGGAKADDLAPDQYHVILFLPAASSEFPSGGRSRGTPLWTPWARWRPSRGPRPHLFLALYGHLAVLRPRRAQPRPGRREPPRQDGHRVPSRRPGPFVSPAVAAGVTLADNAWEPSLAGIDYLRLLEEDAVREAEDNLILEMEADLSTRASADDELLDPLFAHEELQLYPLSFSRRAPHPSSTLALTLSPLTLCLQEPSISVAKPRPIAFAETVYTYDIGTGVLQRPVGRSYALPAREFDDMTGIYCGFDIYSIVPVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYL4</accession>
    <name>A0A3R7LYL4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tetratricopeptide repeat protein 21B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015156</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002886">
        <property type="protein sequence ID" value="ROT66785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYL4"/>
    <dbReference type="STRING" id="6689.A0A3R7LYL4"/>
    <dbReference type="OrthoDB" id="10259630at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000197">
        <property type="entry name" value="Tetratricopeptide repeat domain 21B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056832">
        <property type="entry name" value="ARM_TT21_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056836">
        <property type="entry name" value="ARM_TT21_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056833">
        <property type="entry name" value="ARM_TT21_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040364">
        <property type="entry name" value="TTC21A/TTC21B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699">
        <property type="entry name" value="STI2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14699:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25058">
        <property type="entry name" value="ARM_TT21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25060">
        <property type="entry name" value="ARM_TT21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25068">
        <property type="entry name" value="ARM_TT21_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25062">
        <property type="entry name" value="ARM_TT21_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B N-terminal ARM repeat" evidence="6">
        <location>
            <begin position="12"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B second ARM" evidence="5">
        <location>
            <begin position="271"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="726"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="760"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="Tetratricopeptide repeat protein 21A/21B fourth ARM" evidence="7">
        <location>
            <begin position="762"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="890"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="936" mass="105537" checksum="E2A111D7DF81862C" modified="2019-04-10" version="1">MSEADAVFKGKIHYYGREQYYQAMQNESVAATKKFGNDPVYRFYSAVSHLLQGQTQEAIRQLQPLQNDQDVMLGTLLALIYAHRHCQVVDKEAVTMLDAKLKEERKRAPESCLYYAAMFLLLSGKVDKAREYIDRMLKLNPEDLAGLTLKGWVELFAGRESKIKNTLQLFEAVLQRSPKNIDALFGKAKYYENRSSYKESMETLNVLVVAYPDFTGPLVEKMKVYLSEQEWDQSMDAATRVLSVDSHNIEALKHKTLYALCRQGNYDEAAQALRDLYSEMDRSEPNNASLFVHMAQLFSRICGRNRLVLEETFMMASKAAKIDTGNAEYLTEVGYQCLLQGRNKEATKYYKNATKLDESSVAALTGIISCQLLEGQVDVAEQQLEFLKEVQRSLGASPDILYLSAVLGRMKNQNPDTILALLTEAIDNHFKNHRGMAFGSTYLAALNPDFLLLIVHECLLYAPNQPSDTATTTEVPPVVKRALLVLDAITRACPALLTALVLSARTKFVTGDVKGASTILQHVLDEIDSTSSDAHLLMAQIQLHQGNFKQAQQSLEVGLSYNFEVREQPTYHLVRARVMKKQGQYQEAINTLKSCLNLANTRPTTTKGSRNKAELTLPDRASVFLELCDAYRLNDQPNEAASIMTQAMTEFQGTGEEIRLNIASADLALMRGDVEHALAMLRSIGPDQPYYLEARDKMANIYLNNLKDKRMFATCYREVVEKNPTPQSYLMLGDAYMSIQEPDRAIEVYEQAQKRNPRDSVLACRMGMALVKTHQYGKAINYYKEAIKSGSSNQLRYDMAELQMRLKQYDKSEKTINQALEVEAINHSNLTSMLTQAKLLNLLAKVHERAGHFDQALSTLSKAKDVQVKVLKRAQVELPDSVAEQKQLAGSMCSKMAEHAANQREFDQAIRLYKEALQYDPEHAPTLLALAKLYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYN7</accession>
    <name>A0A3R7LYN7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015093</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01002880">
        <property type="protein sequence ID" value="ROT66849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYN7"/>
    <dbReference type="STRING" id="6689.A0A3R7LYN7"/>
    <dbReference type="OrthoDB" id="2526284at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF83">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="500" mass="58499" checksum="0F83EFBBE6BEC8B7" modified="2019-04-10" version="1">MTGTKTSLFLRNLEALVHVPENVSSEEPNMEEILVVPPTLSPEEKIRRVEKASRNLPMGFAVRSHMKKKMNNSCAHFPSMYDLHYNNMYWQTVETSNGKFHLYGAYYDNRTLEPDRPVVRMTAIINRVGEFAQTNCQIWFEDLEKPVFSEASRVLVWYKEWGHYNNHDLNPYIITCKIPASHRGLVPQAVSLVERPCDYATNLLKVIYNLPENGQKEGFAVCVKGSEFYTGDATVRIIEWLELHFAMGANKVFYYDFGMNRRLAKTMEYYTKKGLVEVIPLTLPDEQPNIPGLVYKYLDAKFKYQHEVIPYNDCYYRNIYRYRYTVHADPDEIIIPRNANSWHELMDIIVKKSKKDKVLYTSYSAPHTFYMDEMLPPEGHFKDIPKYLHIMQHAYRSANYTPPGASIKCFHDTERALGLHNHFPIHCLGGKYNCRSYFISTEDAQMQHYRRTCQGFVQNCYETYKKNTVLDPTAWKFKDQVIAGVNRTLAALNYFRNYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZ35</accession>
    <name>A0A3R7LZ35_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein with SprT-like domain at the N terminus</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_013391</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Spartan family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002664">
        <property type="protein sequence ID" value="ROT68455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZ35"/>
    <dbReference type="STRING" id="6689.A0A3R7LZ35"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044245">
        <property type="entry name" value="Spartan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055220">
        <property type="entry name" value="SPRTN_ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220:SF0">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22934">
        <property type="entry name" value="SPRTN_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SprT-like" evidence="16">
        <location>
            <begin position="4"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="UBZ4-type" evidence="17">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT68455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="253" mass="29764" checksum="42017B0FF53C4F55" modified="2019-04-10" version="1">MADPKVLSLFNEFNKKYFWGKLDKVKVTWSPRMTLCAGKTAYKVRGRSFSSCTIRLSQPLLTQRPHSDTVNTLLHEMIHAYLHVTQGLNYRDSHGPEFRKHMKRINILHGSKITIYHNFHREVNKFRIHVYRCDGPCVSRRPFYGVLRRAIERPPGPTDRWWQRHAKECGGTFHKIEVVLAAEMKLHLQYCIDSDDEDDESFDDRNNKVSEGRDFEDKPRPGIVSCPSCMERVREEQIQEHLDQCLTFLAEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0B9</accession>
    <name>A0A3R7M0B9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003364">
        <property type="protein sequence ID" value="ROT63844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0B9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="581" mass="60526" checksum="5DCDA6A1E355A701" modified="2019-04-10" version="1">MRPWVSPYVVGAVPQPTRPQTGPLLRHPRERTPSARPGKRLTFSRVEGGEQRAPNRQPAAPPLAPARHARSGRLRGGPAPASPRSSPAQHARQGLSARADSAHTTAGQGPLGPGARKAAPPTAPAARTPPKPAPLSGTGAGEAGASSRRRGPRPRPPPPAPPSARESAGGRRAQAARSGARPNQQAAPAPPAQGPRRPRRRARRPSACSRRRWSPYSCRHGPSAHTTAGRGRSPRGPGKAAPPTARQPGPPKPAPLSGTAAGEAGASSRGGGHARARRLRPRPRGRRGRGPTSRGPRTARARPARSRRRARRGARRPPARSRRWPPYSCRRRPSATTTAPRARPRPPAREKRPLRWAIPAGPRPSPTPPPTAREGAGGRRGKAQPAPARGRRGRLTGRSSHRPAALGPRGRGDEGERGKEAQAAKPGAGGPAPTAAAAAAGSRRGRPPPPAAEAVPLSLSAQALSHHDRAQGPPLPVRPGQAPSGVRQGHARIPRHRPWPERAPGADGGKPEPTPVLRKTRQAGQARPGPAPRPEGHGGRRVGKSPSRPLASQGRRGWQANPGGAAATAAPRPQSPLHPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1Y2</accession>
    <name>A0A3R7M1Y2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nuclear receptor coactivator 6 TRADD-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002398">
        <property type="protein sequence ID" value="ROT70699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7M1Y2"/>
    <dbReference type="OrthoDB" id="5967287at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026638">
        <property type="entry name" value="NCOA6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032715">
        <property type="entry name" value="NCOA6_TRADD-N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15690">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15690:SF0">
        <property type="entry name" value="NUCLEAR RECEPTOR COACTIVATOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13820">
        <property type="entry name" value="NCOA6_TRADD-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear receptor coactivator 6 TRADD-N" evidence="2">
        <location>
            <begin position="38"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="955"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1410"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1472"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1508"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1745"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="619"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="725"/>
            <end position="735"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="985"/>
            <end position="995"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1024"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1039"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1265"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1309"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1338"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1482"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1508"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1541"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1745"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1780"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1812"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1943"/>
            <end position="1974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1975"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2012"/>
            <end position="2023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2032"/>
            <end position="2055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2056"/>
            <end position="2077"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="2106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2106" mass="222229" checksum="3ECC92760E32112D" modified="2019-04-10" version="1" fragment="single">MHRKQQRRACCSGIYTDGTKERPGALGVLHPEPMKDSTWFVRKVEPWNSVRVTFSIPREAAVRLHQLAQAGDQALRQLGILSVQVEGDQVISLKVAGPNNESTEIVLRTDGGASDGAGPSSVARSVTTALGSAGLMTGAAQPTEVVAAPPYRSVAPNVVAPVGDSIPLTPRPMPQVRPPFPYASMNHAEKTRQGRELQHQQPSGSAPVSHAVPGVGQRPIYNPPPPYPNHDPTQLRSAGAPVQRPPVPQVNGTQYVVSQASGGGSVSQPGTQVLPSVVQASANQTVTGGFPVSVSQTVNNRAVPAQPGKLGQRTGGNVVKNSPLLVDLLRQPDHQPGVGVSKTKVVIGGSPHGSPAPASPSSRSTTSTPSSDSLPHTPLNLPLPAVPALSPPPASSTTYSAAIPASGLTGVASSNQFSSAYTVRAKDGVHTHQQVYSGGSVITSTVTPHPRLPSSVGGGLQQHPQATGQPPPGPRPHYNAEQRRLSTGTAPNMHTRMPVQTPARSSSMGETKPVSPSPPQLGSGGKESQYLINPNTGLLEPRPSESSDSEPEVRPPSPMVEDVRSNSLGSDEESNMSAPSRKETDQSDSETSRMSVHSVESKKAAVNQDRSKSRDRDSSPGSSRENSVVSSGSSDVAIRLKLKIGKEPITQATFVPNAKKSDRKEIANSSSGSQPGNEPRVPKLHIKFDSNQAVIVNPGDGRRGQEKDGAKEDKSKRRSYRNKSRSSESDSDSGRVRALKVKGSKAIGDESSNALKFMDVKKVKMEMDMEENPLKVKVKEGVEGRLKIPRTLEDNRLSGMKSESSKISKPETKLKTRIKTKQPIRKVGDLNSMGEIASHKILETLPPSITKVAALHTQQPHRNPSSSSQSSLVSSAAGTSLSAVSSGTSSQPAGELFKAELEKRGSEIIRKSEIKNDLEKNSADSLINRLRLMNGDVTHGENKLLMGRIRQKTAGGSKLTIKRKGSGETHTLESLKKDLPEVPVSSQSESTNSNSGVKVESKVMETPEKVKQEVKCEEKSESNEPHIPSVNSSSSCDTSVKQEPEQTKVLEQAKGPDFPGSVILTKSEVESPDGTPKGEHGSGQGGEDSGIESMDALSEKSPNQSDQSPSRREDKECEAFHEKSDKAPVSKGESVSTCRSNVTPSIAGNSTQEEPNLSAKIEIKSENVEEQEEGETTKSENDSTTAKCSTQQCESPKDKSDTTECRQTDTNTTAQESCIKSEEQPTKSVQEVTSPKELPVPVADIKNESIESVTPGQADDESKGCETNLSSFPDPSTSCSTSLPSGSTPLVPVSSFSSTCSSISSPASLTVSQPSPVKSPQTSLPVSVKTEPVTTDTVPAVSQASSESSVNNSSSPTPPSSVSTLPTQTSSSTADVTPTSSSSSTANLLTLTNTTNTTSTVLSTTFTVPTLSVSTPSTPTSTPTSPTSPTSSSPSSYTPDTPSLTVTSNTTCTTVTSTPVSTFSSTFTPITTVHSIPSVPDTPKTTSSSTTSILSSSKPSLLALTLTRPQTSSAPSQPSSTQVASPPAVDKVASSPAPNDSCCTISTSSSSSSQPTVTSTTTVAATTTSAKLVTLKPSTSQGQVSTPLNLPPGTTFRLVALPGKSAMAPTTSPVKVVVSPMKGQLSQQVTSGIGSMTVVTVKPVVMATGGAKNSHLLQTLSVSKTEESSPPSLLKAHLTAPTLTTAAQALATSVTNSATTPIVSSTMANGDDTEDLDFVGFSSSPQVKLLQPSELKREILKTEVGETRRAESCKSPEVVSPTGDEPTPMRVHPPLYTYGNRERKKDVESDAEDKEKEDGKSMSECEGSSDLKCSDLSELDKEKEEGVKPKTKEKKFDALSIEIPPTDPTLPDDKRLTRSTRHSARLASPKVSSPGAELSPKVDRRSPASMSSMGKPSPVPVLRPSVSPATRGTKRRRHESESSNASSVNEETQEPATKSTRRKPPDKIGGEKEECQKVKVTKPKEADGETKSSKDEEDSSGDESLEGGSTKKRNPSAASTSTNEDEDDSRPSSRSSRTSCKASARSRERQSSAESTGTTRDTTPTRRTPRQNNRAPNKEKSPEPAKEKGQDKEKDKSPVQGAKTRKESDPSEPDASNRRKTRSTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCA6</accession>
    <name>A0A3R7MCA6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001327">
        <property type="protein sequence ID" value="ROT78835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCA6"/>
    <dbReference type="OrthoDB" id="6358034at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="23761" checksum="756044799D2D3C6E" modified="2019-04-10" version="1">MNPGEEDPCTVYGSEMHSIPMSYYGRDSYSACASDAPYSLGQEPTTFGDAQDHPLTASDDPSYRSSYASCETPWGVASGAASFPSDGTADVTADPQQQPALAGRRRRQRKPKLYNLPEQDDPEEEMRRQRAKREKEKREKRHQDEVNMKRETEKTLEENRLMKVEKELRSCNINMMEQLLAMSESAMYRGQPDETGEFDPYGQYQQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ME97</accession>
    <name>A0A3R7ME97_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001941">
        <property type="protein sequence ID" value="ROT74073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ME97"/>
    <dbReference type="STRING" id="6689.A0A3R7ME97"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="596" mass="66245" checksum="5E766318CDC271BE" modified="2019-04-10" version="1">MSFRDRRPPRIPAPPPAPRRCRANCFYGAGNPTVKTPKTTPPPPSTPFLAHFLLLRALFFLRLPLLLPIQTLFYPTASTSILFLSYSLALPLLFPSHSCPLPLLRPLRLFLPSPPLSTLPLPLLFFFLLFFLPLFEIILPPTPTTPSILFFLHSPSSFHPILAHFPSLDLVLPPLPPPPSILFFLRILFFELILPPLPPPYILFFLHFPFLDACSSSAPPPLHPILAPLLLLRPLFFLAPPSSLPFYSSSTSPLELILPSTSPSYFPFYSFLRILFFEIILSSTPTTLPSIHPPLPLLRPLFLFLNYSPSLRSILPPLPLLRTYSSSTPPPPSFYSSPFLILLFHLPSSFHSILPPLPLLLPNSPHLRLPPYSFSFLVLPSKSPPPSIPILPTSLSPHSLPPPPSTLFFLHYPSLHPILLLKPSFHLISPHPLHPLHSPHPPPSTCFSPSPSTSFSPPLPPYSPPLSLLSISLPSSCPTRSPHNSLSFNLLFFLHFFLHFPFTTFLFTNLLWCLNISLTFISVDLYDPPPSLPPPPSLPYPSPPPLPPPLNISLSLHPSLPLTPRPPPPPPPSISLSPRVHLSPPSLLCLPPRPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFX9</accession>
    <name>A0A3R7MFX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001793">
        <property type="protein sequence ID" value="ROT75282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFX9"/>
    <dbReference type="OrthoDB" id="6341359at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="44017" checksum="78E96372123116F2" modified="2019-04-10" version="1">MSSVVPEFFLWDQSLNSSCGGRMECETLYELGPPPDMILNIPPPPIPPFMEEFVARLAAEGINIHEDDNGFPEEEKSCNLCQWANGNGVGFVELAQKGPLIDDTWFLVIISSCVAATLLGIILAIAFLKYREGKLKPLSDVALAKKEKALGLERCEAVLYPAPAITPTPVPQLDNRTSRALWAGIKPLEGNHYTVDHCQPMEQKPVRLDLLPPHDNTYDYADYSSVSYASASYTTLTPRLDGSSPRPQPAASFENVGYVPGDEGAEVERVAPDGCVVTAPRAARLLGSPRFVQGIQDHHHYEMVTPSMRRHKSLERGARQPPVISGPTSLGPVRMPPLNGRPRYNLTAYASGTHTLTPKVDNSARAERRHAHVSLDRSGSANTTLAPASPTDHIYASPITSPVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJK4</accession>
    <name>A0A3R7MJK4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_018748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003447">
        <property type="protein sequence ID" value="ROT63379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MJK4"/>
    <dbReference type="OrthoDB" id="6350762at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="83"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="811"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT63379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1286" mass="141908" checksum="43515C910EBA3D72" modified="2019-04-10" version="1">MFWIRVTPPWLCVRHRMECWGIPGNDVGLLIRRLSADFTFISSFPTRDLIDAVRSGNVEAISTALSRGADQHLTLPEDDPDDPGGSLLTLAARLGHASAVSVLLEAGTHVDHRGHGSRTPLYRAAYMGHADIVEKLVAAGAYLEAQEGDFACTPLHVAAQQGYASCIQKLVDAGADMYARDIWASIPLHRAAMNNKPAAIMQLIECGCDPQVKNKFGKTALHFAALGGGLESAKVLVMNNLNYHEKDGQGFSSLDIARVYSHHEVEWWFLKNPSPEVMRLPMAVPKAKDSECSSSGLPVDGSLPDSSSPVSPLTNIVEVTSHTGAENAPVCTKPDNTKLTIQTNTATEDGVQSTETTADKISVTIKKAVTTLKPKISPDTRHIMVDKSLRIEEELSKSILEYIRRGASHLLINIHHSHDGHYQDKNGLTPVHWAVTLREARTVEVLLDVHKLYPESLSYSGETPADLARQAGNNEVLNIMKRFQVIKKVEDPEELYEELLTVIGSGDDAVKASELLCQGAPLEPVGSLSTHALSLAVTSNRRKLVSLLIAAGAPLTSMAGGLTLLQQAWNSSDVTIRVQALITRAYKNRLAWEKRQLPPRESLLHQGIDRMLDTLGGPTPWKTKWKFLGVKTLTALMCTAAQYNCILTAFFLQQAGAQSFLLSEGGCTSLHAALHFKHWNLAAAMVKDMSASLYISDSSGVLPKDIMPNYLREEIEEALHAKEKRKLDDMYEKLKDESEKEDVKLIIQLSDDLFSIYRNSDGSNSHEIPPYLSSIVCASLSVAAQRGLLQLMYMIVKVCGVQPDTVVDYTNDTTALHLAAAHGISGCVALLLDLNANPLQPDKYGHTALHFAAMNCHDSTYQLLAAMVHDEEPVSVAGTVPSEIKENVDKYLKLYRKTETAIKDNSNVPERTDPAEATVTLLKQVGLSDIVDDCSDFSVDFSEGEAREVSTAVQKECQIIANGVALQDKTYEGTLTLVGSSSDGTRLYAPDECDISIVLSNIPDIEITVVEQNEREVLDCGHRLRIEVRTDAPKFQGNTLIENLYSLVTSYLESHILHDKRLSVVPPGVTRTQVGVSLSFAWQGRQYPLLLVGVDLVPVLPLPWPKDVLRPALTPPDIEEVHLSNKADGTWRCSFAGAEVAVISQLSAEERRVFLSCKTLLSRLKAEVWMPRDVKSLYTWWDSRQWKIPIPAGFALKNAFLNVLEWKRREGVEWREKDLLKWMIRVFREMCQADVEFLADQEQVQAREVLAPKKVYAYFGGDFEKPKVGDGAPDIIGILEQELRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKE3</accession>
    <name>A0A3R7MKE3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_021235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000442">
        <property type="protein sequence ID" value="ROT85126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MKE3"/>
    <dbReference type="OrthoDB" id="15627at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
        <property type="term" value="C:stress fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032034">
        <property type="term" value="F:myosin II head/neck binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051496">
        <property type="term" value="P:positive regulation of stress fiber assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051893">
        <property type="term" value="P:regulation of focal adhesion assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15551:SF3">
        <property type="entry name" value="LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15551">
        <property type="entry name" value="LIM DOMAIN ONLY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="1394"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="84"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="203"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="442"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="536"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="945"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1350"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="700"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="985"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1126"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1148"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1179"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1246"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1366"/>
            <end position="1385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1443" mass="160931" checksum="6071E7A78D75339D" modified="2019-04-10" version="1">MWPLCGLVTDSVRSSTSSPPPLPPSPRARTMRTQIGKRTWTNGKARGERGTRTRSRENKRGRRYNLVVHDDDNNDLADLGLSTVKSSGSLYDGQEDNDVKDLDQDNKDAKSDAGFCTGSDTGSDGVFAEDNISDTSSALGDKKETHDSLLDTGVSKEEEPRINGHGSSLTSDILNTNNANLYTEEYTYDKAIEGYKQYAENTAKKRTSSITSLNSNTSFTKEDERKDERPRLNGRSPSPAKSNKLEEKLNFFTKEMVKESRTSPEPRVIMREKSPKVDVGKRRSMFEMGEPLISQSEREQKQANRRSLEVPGSLRNKVASFENLDMDTPKVRGMTPNIETNLKSKVKSFENLDTETTKVRGVTPTRDTKFREKLASFAAADTESQTVRKKTPERDVNFHKKLASFTSIENGEEEKCVERKTIPLRDPTLKNKIASFEQLEQAAEAYSQPPREEPMKNRDRSVSLENLDEPPPVKEVMRPAVSMGNMGLMRRAPSTPYMVVDLDKTGVEEESCIREKRPVVNAQVFEIASKLEETPLLGSPTLRDPSVPLPEPPVQEQDSFEGAKPYTDEDINEVISDYEQVGSVYEEASEHVENIYENITEEPVYENIYEKVLDVTWTDGPSQAAPPCVPLPPPPPDDDSDDDASDQPQGLPEQAEDEPFTRENSTRRIKKELWRRRSDFLGTSSQYIEEEPTVKPPPDLSELLRQEREAERIMAESQRARTPIQETLSKAEIARREKEIIESLERSEQLKQQQQQQLQYTWQDHMAEETTMTEEQKQLSEHLEYQVAQTESTSSESDIDIQVATNVPVTSANIPTTSQSVMDSKELETMETSSQSPDETFEALPISSKDTVDSVETKAEMLETHVIEPNTTVAKVLPTQTQMEVEAENNVQPESSQQYTDLLESHYSTLDYSSDSVASTGSHPDPYKKLAELEEEMMRHDQDMLQRAGKLAPASTISNDAQPAHIPPPTMYASQEGAPVPSPQAPQTAENNNYSNYQPPAPQLPIQEFYTAPTYEPTPPSSLAPAEGVASPGQKAVSPPTGSPSQYSTLASPHPFTRSHSQSSIGAPPIHPPLQGIRSSPTGSPRDPAPEPLPRKKKLPPPPPSKPHQISGDSTERSEAIRLSRMPTSNPNSVSPQPQEIQGEAVSPSGQQMSKQTLLALSAIPKPRLTDNESWITKKKPESQRRDYSKHWLHQEAEQRRLEQQDRVNRQQQARAPAPKTLPPQSVSPQQPPHPQTTSYLPTYPPQNASPTYSSYPQALKNPSPIQSNNNNNNNMWRNQATTYQPHMPTQAPNGDKALPDSIIHNITQRVNNKNSKNTYSNTNGRLGNTYGNNNYRDENYHDYMNADALSAPSTHTPLYQSGMGPSQQPPFNSQSQDHSSGQDQRLLSVSGKKKCSHCSEELGRGAAMIIESLRLFYHIPCFKCCVCGIQLGNGSAGADVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMZ0</accession>
    <name>A0A3R7MMZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003028">
        <property type="protein sequence ID" value="ROT65845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMZ0"/>
    <dbReference type="OrthoDB" id="6371124at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="46738" checksum="F97F78F9BBF577DC" modified="2019-04-10" version="1">MITMIITGLNGNGSREDDEGDDKGIPIADLVRRPTHRPTARDATVYKGGTRFQALTRASSSARRRSVTLCNMTLKVFFVAAAVLCLAQAAPQRYDTLGVLQPETPRDLGAYENIVGATIDVLPEIVEVFRKVSQNRDRANDPESVQQIMLDFMPITRKVMEATAKAEGNNISQDTYQRFNAAEKVMPHVVTFMNQLREMDFFGVLYDEASLSLSLSHSLLPPPLFSPPSHLLLSLLYILSSQSRLHLSSPLLRSLLLSSQLLRLSLLIKTSSQSFYPSVSGHGPRSLSLSSRLPLSSLSLLSISLYCSLLTLMSLSQVFLPPLVKPVPSLSLSALCSLFSLPSSSDMSLLLILDFYHTWVNAFYTYFVKYITFLGLLLTTTLSSSLDLRSQGIPRSSHLSPSVTLINDASPCSLPPARPASSLSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQP0</accession>
    <name>A0A3R7MQP0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Serine racemase</fullName>
            <ecNumber evidence="6">4.3.1.17</ecNumber>
            <ecNumber evidence="15">4.3.1.18</ecNumber>
            <ecNumber evidence="16">5.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">D-serine ammonia-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">D-serine dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">L-serine ammonia-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">L-serine dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C7M84_014393</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="22 23" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-serine = D-serine</text>
            <dbReference type="Rhea" id="RHEA:10980"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="5.1.1.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="6"/>
    <dbReference type="EC" id="4.3.1.18" evidence="15"/>
    <dbReference type="EC" id="5.1.1.18" evidence="16"/>
    <dbReference type="EMBL" id="QCYY01002804">
        <property type="protein sequence ID" value="ROT67529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQP0"/>
    <dbReference type="STRING" id="6689.A0A3R7MQP0"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030378">
        <property type="term" value="F:serine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018114">
        <property type="term" value="F:threonine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070179">
        <property type="term" value="P:D-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006563">
        <property type="term" value="P:L-serine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01562">
        <property type="entry name" value="Thr-dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000041">
        <property type="entry name" value="Threonine ammonia-lyase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050">
        <property type="entry name" value="SERINE / THREONINE RACEMASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43050:SF1">
        <property type="entry name" value="SERINE RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="21">
        <location>
            <begin position="20"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00050422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00056426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00066592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00070760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00076108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00081060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00081761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ROT67529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="248" mass="26647" checksum="7121FC4B0A566141" modified="2019-04-10" version="1">MSTTGVGLQEVRAAYQRIQGWIHRTPVFTNEGLNNLSGRKLFFKAENLQKTGAFKARGACNAVFLEKEKNPKSPGVVTHSSGNHGQAVAYAAKCAGLPCSVVVPKGTPKVKCDAIVNYGAELVFCEPSPAARKEVCAQIAEATGKAIIHPFDNYNVMAGQGTIALELLEEVPDLDAILVPISGGGMTSGIAVATHGLNPDCRVYAVEPFGKELQRSLENKKRMWDNPPRFLETIADAIRTQQVREAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N150</accession>
    <name>A0A3R7N150_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">UV2 opsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_007030</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001891">
        <property type="protein sequence ID" value="ROT74460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N150"/>
    <dbReference type="OrthoDB" id="2105199at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00577">
        <property type="entry name" value="OPSINRH3RH4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="16">
        <location>
            <begin position="140"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT74460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="49708" checksum="05E15BBA81D2027B" modified="2019-04-10" version="1">MPFAQSYPRPLLRCTCTASDAAFIAVAEQTYTSMTTMSDSIFLLPYRVRVGTMSTLAGPHVPTAAQLANVTDGLDAASPLFLSGAVASGRYEVKMLGWNTPPEYMDYVNPYWKTFEAPNPFLHYMLGVFYTFFMFAALCGNGVVLWVFTSAKSLRTPSNMFVVNLALLDFIMMLKTPVFIVNSFNEGPIWGKFGCDIFALMGSYSGICGAMTNAAIAYDRYKTIAKPFEPKIKSGTAFLIVLGTWAYATPWCLMPLFGIWGRFVPEGFLTTCSFDYLTEDENTRTFVAAIFFFSYIVPGFFIVFFYSQIFSHVRAHEKAMRAQAKKMNVDNLRSVGSKEDQEKSAEIRIAKVCMGLFFMFLVAWTPYAVVALIGAFGNRSVLTPLVSMLPALACKSMACIDPWVYAINHPRYRLELQKRMPWFCIHEDKPQDTASQASNNTEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N5T8</accession>
    <name>A0A3R7N5T8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Y+L amino acid transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_003254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001444">
        <property type="protein sequence ID" value="ROT78050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N5T8"/>
    <dbReference type="STRING" id="6689.A0A3R7N5T8"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000095">
        <property type="entry name" value="B(0,+)-type amino acid transporter 1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF528">
        <property type="entry name" value="AMINO ACID TRANSPORTER PROTEIN JHI-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="630"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="693" mass="75178" checksum="58081B845BAE97F9" modified="2019-04-10" version="1">MLPAAGGEYAYILAAFGGLPAFLTLWVNVLVIRPATQAVVALTFADQKWRDNFKSRHRFIRRLMRPSERARLLTALFGHGLLLPGTLSSVTHVVRFASLISPSFVSPSGSPPLSPGILCRRPHTSLSRDFSTVWVLSSRLRVAQAERKTELTYANLTAYLRLANKSRLADDDGGDGRPFPLIWTLSVPLSSVLSSSSVGLAFLSSAWAFSPAPFSLIQVKLLQLLLIISLLPLSFPSIPLFSPTLITPLLSSAFVIPSFLSPPLFSLPKPANFVVVASSFKGEVHAECSSRGLSGYACAYACCPYDYKRRDSLEGADTASLLRDQRACDWRDEGSAQRLIYLITGLGRWAARGVVGLLTFINCASVRLTMRIQTLFTGAKLLALVVIIGAGAMHLCSGHTEQLERAWDGEHSVGGVALALYSGLFAYGGWNYLNFVTEELKDPYRNLPRAIWVGLPLVTVIYVLVNVSYLAVLSPSALMSSNAVAVSFGTIMLGPLRYAVPVFVALSTFGSLNGILFTSGRLFLAGARKGHLPPVLAFIHLRKRTPVPALAITCFLSLCMLGADIISLINCLSFVLWLSIGAAIAALLWLRTTQPQLHRPIRVHVALPITFLACCVYLVVVPMVTEPRSTGMGIIMTLSGIPVYVAGVLWKNKPELLNAVHKSVTHRLQRVLLVVEPDEPVDVPLLPAGDAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7R5</accession>
    <name>A0A3R7N7R5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative glutamate receptor ionotropic, kainate 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_001802</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001238">
        <property type="protein sequence ID" value="ROT79475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7R5"/>
    <dbReference type="STRING" id="6689.A0A3R7N7R5"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06382">
        <property type="entry name" value="PBP1_iGluR_Kainate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000106">
        <property type="entry name" value="Glutamate receptor ionotropic, kainate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="11">
        <location>
            <begin position="372"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="48786" checksum="D3B33C9915534C72" modified="2019-04-10" version="1">MCNSAITADCDFNQHSQYVCYLVRAGVAAIFGPQSGQTSAHVQSICDALEIPHIETRWDYRLRREDYSVNLYPHPSSLSKAYLDLVRLFGWKSFCILYEDNEGLVRLQELLKTPPPNEFKVTIRQLPRDNDYRPILREVKNSLEQNIILDCKTEKVGQVLKQAQQIGLMSSLHNYIITSLDLHLVDLDDFKYSGSNITAVRLVDPDSEEVKRLMEDWERRSPQYLQTTEGDDVILKQQLGVDFWTTETALIYDAVRLFVQALQALDNSTFVQVAPLICEGEEAWIHGNSLINYMKMVYFTGLTGFIKFDALGFRTDFALDIVELGMQNLTKAGTWRLDTGANYTRTFQETLKKVVDGLQNKTLVVSVAYNDPYIMQSENADDLAGNDRFEGFCIDLLTEIASILKFNFTLVPVASNAYGSKTLRRASGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N9Q7</accession>
    <name>A0A3R7N9Q7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000203</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001033">
        <property type="protein sequence ID" value="ROT81044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N9Q7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018624159" evidence="2">
        <location>
            <begin position="19"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="689"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="782" mass="84216" checksum="99EA31037EB9D4A6" modified="2019-04-10" version="1">MLLPVFALLFSRNLLSAAAPDPGPPLEGPSPALPTQGPPLSGEFPDTSSGDRLDSVRPPTLRYGSGVGDDVGVGGSRKSMPAFANLHSTENGSTKKMELSVVCPDDSIFHCNDVSTMSSTQILNLTKELVNKTNIAPEADLVFNTRENMIKLTFMFDNKSVSVSEYFSETNDSHRPKINVTVTVKNVKRSVKDQLEESVSHLGEAEEHDRGMMMKMLDMISEVAESVYEEVTDAEREEGTTATPASPLHTETRPQVLLEEAATLTPGTLPPVLSLLSTTLRSQLAYPRKGEPTTENLSLDTRSVRIHSSQNGQLASSIQRSWVQENIPATTAIPAVPFSNVTPSPSASPTTESITSDWPEENQTGNFRLSEQMNPTTARSSEEHDHVNADEVLIHTAPRVTQTLSDDDLQFYGNYIDLSNSEFSAQAPRTVSINDEEWTAAQRENDDEFSNYPGLVSKQLPTEPRDTPLGPSSSLTDRQYNYGGAPSPSPTPVAAWHHSHHHRQHKGNTWLPETAQPLPSTTLQLPPPDAESMLGTFSRFYKMFDMMMSVVDLAKNVAALSPTTSSEAAPSSPHPSTPSPQSTPISSSNVLPTLIPLDLMESHHTTDTSIPTGPITTTDTSITTETIILTEPPAAYITTDTLVTTGEIIDSNTDTTSSIITVSDTIINIDVPASASFIINTNIPSTNDIPSTTDIPSTTDTPSTSDILATTDIPSTTDIPSTTASTSDIPSTTDIPSTSDIPSTTDIPSTTDIPSTTDTITDIPSTSDTPLTFLPPLTFLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NP73</accession>
    <name>A0A3R7NP73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003498">
        <property type="protein sequence ID" value="ROT63070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NP73"/>
    <dbReference type="STRING" id="6689.A0A3R7NP73"/>
    <dbReference type="OrthoDB" id="21589at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039751">
        <property type="entry name" value="HERPUD1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943:SF27">
        <property type="entry name" value="HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12943">
        <property type="entry name" value="HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="20112" checksum="A719A329B942A269" modified="2019-04-10" version="1">MNAQGGEVEDDDDDEGMGRDWLDWIYVLSRMVVLLSIVYFYSTVSRFMIVVCIAMLLYLYQAGWFTPARRVEQPREADENENENDNIQDDRNNNINNNNNNNDVPVEARNQGEEIPGEARNPGEEEAGAGDNQGNTQGNEGTDRVVEEIPVRPSILALSWTFLTSLFTSLIPEQPQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NVQ3</accession>
    <name>A0A3R7NVQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002731">
        <property type="protein sequence ID" value="ROT67996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NVQ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="40621" checksum="30C6C04349314463" modified="2019-04-10" version="1">MERTLYLLLFKDYEERYYRFFCSFACRCPGDSSSPGQQQQLLEGGHRLGGKETDSFWDVFSQGVYLILQTTSMIDASFFPLALPIPSSPCLLSLFSSHLLLSPSRVYRPFSLFPPSLFSFPICPLSSCSSLLTLFYSPSCLPYFWKQARPLTPAPPPPSYPPSALVLSPLPIPLMSLPSRPVPHFSSSLPPSPPPLPPLSMTLLLLLFPSLCPSLLLVPPLRPSSFPSSFSSSFLSSFSFLPSPPPLFPSPSSPPPPSLLPLPPLLLLSPLLPSSSFFLPPPPSSSFLLLLLSFSFPLLLSSSSSPPLPPPPPSSSSPSSSLFFSSSSSSSSLLTLPSLLPLLLSPSSSLLLLLPSLLFLPLSPLLPPSRPRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P500</accession>
    <name>A0A3R7P500_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_005865</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001756">
        <property type="protein sequence ID" value="ROT75577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P500"/>
    <dbReference type="OrthoDB" id="6375714at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="11">
        <location>
            <begin position="62"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT75577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="350" mass="39527" checksum="1C2CDE954A8B4516" modified="2019-04-10" version="1">MLGTCGAGTRTSPSTTSPSPSERVEDFDYSVSHYNEGFGFSIMIPPPLPRWLNLIYPFSLLVWAAVGGSLLVTAATLYALSYARQHLSPFQSFIFTVQSLMNQSIQKIPAPWPLRAFVAVWWITAYIIVISYTCNLIAVLTVPVYPKRIHTIKELADNIIKLKICMLDYGEFFPEALATSSDATLFALGSKLDLSPVVETQYYGRKAASKWCWTATTRTEMGHGDEVYFVKEQIYEANLAFFFRKNTPWKYKFDQGIRRLVEAGLVHKWYDDIMDGLRRKHSKEYSQSESAEKPLTLPISRGLSSYTPSANCCQLSSSSSNIFPRNSRPTARQSSNCSIFPDRPLEELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5F4</accession>
    <name>A0A3R7P5F4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exportin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_020464</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004011">
        <property type="protein sequence ID" value="ROT61724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5F4"/>
    <dbReference type="STRING" id="6689.A0A3R7P5F4"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001255">
        <property type="entry name" value="Exportin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exportin-1 C-terminal" evidence="8">
        <location>
            <begin position="421"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00073514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT61724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="788" mass="90573" checksum="468D3DF0BB9E51AF" modified="2019-04-10" version="1">MFSQTITNWKRCCQLDTNIREAYANGQDAEQQFIQNLALFLCTFLKERGSLVERRQLSDALLKALQYLILISEVDDTEIFKICLEYWNALASDLYRESPFLPPTGSSPLYLPRPTSRRQFYQPILTKVRALMISRMAKPEEVLVVENEQGEVVREFMRDTDSINMYKNMRETLVYLTHLDYADTERIMTEKLGNQVNGSEWSWRNLNTLCWAVGSISGAMQKKMKSDSWLLLSKISWVSVSKREAKDNKAIIASNIMYIVGQYPRFLRIHWRFLKTVINKLFEFMHETHDGVQDMACDTFIKIAQKCRRQFVQMQVGEAMPFIEEILSSINSIICDLQPQQVHTFYEAVGYMISAQTDQVVQEHLIEKYMMLPNQVWDEIINQASRNVDILKDSDVVKQLANILKTNVRACKALGHPFVTQLGRIYLDMLNVYKVMSENISAAIALNGEGVTKQPLIKSMRVVKKETLKLISGWVSRSEDHTLVLDNFIPPLLEAVLLDYQRTGVPSAREPEVLSTMATIVNKLESHITLQVPQIFDAVFECTLSMINKDFEEFPEHRTNFFLLLQAVNTHCFTALLNIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILYQLLQNISTHERAASSFYQTYYTDILQHIFSVVTDSSHTAGLTMHASILAYMFTLVEQNRITISLDQANPTAPSTNNVTYVQGFVANLLKAAFPHLTENQIKITVQGMNDLNQDVPAFKEHLRDFLVQIREVTGDDDSDLYLEEREAALRQAQEEKRRVQMNVPGILNPHEIPEEMQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5V6</accession>
    <name>A0A3R7P5V6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Potassium channel subfamily K member 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_005052</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001669">
        <property type="protein sequence ID" value="ROT76354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5V6"/>
    <dbReference type="STRING" id="6689.A0A3R7P5V6"/>
    <dbReference type="OrthoDB" id="297496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF352">
        <property type="entry name" value="BCDNA.GH04802-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="9">
        <location>
            <begin position="52"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="170" mass="18755" checksum="75E316F473507193" modified="2019-04-10" version="1">MRCDIGSLGYYRSASGTIRPVTASPSRGNAVKSSSGDKPRPRTIPITWCLLVIAVYVFCGGLVFSQWERWSLLDACYFSYISLSTIGFGDLVPGRTVAGQDDAQLVESQQIICTVYLLVGSALVAMCFNLMQEETIENLKSFWRNLGCLRRSEVEDPDVEMRDHVQGDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7Z1</accession>
    <name>A0A3R7P7Z1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="13">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_003261</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001445">
        <property type="protein sequence ID" value="ROT78038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7Z1"/>
    <dbReference type="STRING" id="6689.A0A3R7P7Z1"/>
    <dbReference type="OrthoDB" id="6425924at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 13" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13 16" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="15">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT78038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="13817" checksum="141DEF6E528D58D3" modified="2019-04-10" version="1">MSIGVPIKVLHEAEGHTVTVETMLGEVYRGKLLEAEDNMNVQMESCTVTYRNGQTARLENVFIRGSKIRFLILPDMLKNAPMFKNMTGRKGGAAGSGKSAILRAQAARGRGRGGRGGRGWGPGGAMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFA2</accession>
    <name>A0A3R7PFA2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate sulfotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000449">
        <property type="protein sequence ID" value="ROT85066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFA2"/>
    <dbReference type="OrthoDB" id="6352484at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="26255" checksum="03A1E59E1BEFE9B6" modified="2019-04-10" version="1">MFFRKKIFRGFALLLATTVMLSHNFLSRVNDRSSAGKEESARSPHQEGDHAEPPAIAGSSTWRVHVRRINGGPPANVSVEDDKRRQTFLQSGLRQVVASTVSSSTLIMSVRHPLTRLVSAYRNKYDDGKPMRGYNRKREEEKLKVMHTPRWNENFHQFWIPAMITNGLLTQNISAEIGLDFIFEPEKLYDPSVYLKIFKLKRPVITFIQFLRHVITTHKNQSPDNHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFH1</accession>
    <name>A0A3R7PFH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002484">
        <property type="protein sequence ID" value="ROT70015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFH1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="53714" checksum="623D444A4723128D" modified="2019-04-10" version="1">MSVPAARLDVRGHDTRGGPPSRRPLVPHPQTHSLARPPRRNPIHPAFHRGAPARARAREPSTPPPSLSHPPSIGMCAGAKDTPPARERCYPSWDTDPVEESLGPALSSPRAPRSTPGPRRRFLSASSAPPPLSSSPPLLLFLFFVFLLLFLFFLSFLLRFLFCSFSSSFFCSFFFAFFFCLFFSSFLCSFLLRLSSSFSSLLFLLFLSFRLSFLPFSSSSFLLLFLFFFVFLLLFLLFFFLLLLFLFFFVFLLRILLFFSSSSSSSFFSSSFCSFFSTFFSFSLSFSSSFSLSFFFSPFLLLRLSLFLLLFLCFPLPFSSSSSLSPRPLLCFFLLAPFFFFFAFFSSSFLSYSFFPFALLFFLSLLLLPPTPPTPPTVVTAPPPSLFSFILILFSYSPSPSPPLFSPPAPPIIINVATSSSSSHQFLPSSHFPPVLHPLCSCSFSSFPSSSSPPVPPPITVLVSLLFSLHPLLSFHPIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFU6</accession>
    <name>A0A3R7PFU6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_016895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003133">
        <property type="protein sequence ID" value="ROT65144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFU6"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000759">
        <property type="entry name" value="zinc finger protein 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000688">
        <property type="entry name" value="zinc finger protein 197 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000184">
        <property type="entry name" value="Zinc finger protein 333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001119">
        <property type="entry name" value="zinc finger protein 408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000110">
        <property type="entry name" value="Zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="212"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="328"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="407"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="681"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="681"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT65144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="898" mass="95851" checksum="0AFABDFBE2840417" modified="2019-04-10" version="1">MKVKQQRGEEEEFLHVVAEASDLRCDVCGRDFDRRSRLEAHYKTHTGERPFSCPFCGKSFASKGNCNTHMRVHTRERPYQCPHCDKKFSQHGQLVIHIRRHTGEKPYVCPHCSKGFTCSKVLKIHVRTHTGEKPFQCEYCHKGFAAYANLVVHRRIHTRERPYACHLCGRAFEHSGNLSRHVRVHRVDGGLRCIPCGQVFSCEQDLDLEQFQPPHGYQPPECEPQLTLLTPLAPSPPAETPLPQPSEAEDAPGEARGCITLSDSEDSGRESGGSTGYATSPDQAFERPPPETSLKAEAPEAPPPDAKPSAGLISTTTHRDGVRETLATSLPSAMPAPTPHIRMPPKKQQYPGGGRTPLSRPPPNLASRGAACVVDGAAAAPGCRVSPHLLAGAPAPAHGAAAHLDHGAAAPSSLGPPSRPAWCPHGGGAPRRPLPARAQRPELAPTSTSTSCPSATRPRPRGTPRPSASARRPSPPVPPEAEAHGGEASAAERLSPLYRSSPRPPSPADADANPLDLSRPPGPPGGGGADASPLNLSQRLAGAHPGGAESCLVGYGGQAAHLLTPAPPLPSHLLTAPLPAPASSRSNILRRKSADVAHADPKKNKSRKVAPPPLIPIRSPEEAPAPAPSSRPPEALAHHHPSSMPAPPPSSSACHPYRAHIPSTPTSAPSTLVSYAPALSTTSKTSPALPSSLSPPLSAPAPHAPAMPSRLQLPIPSPRSKLEEPEPDVIVESDLPKDKFLSCSKPNLSMRENIQRSLLSLLPGEHEAASFKRKVETALVVLVLITILDMAGKGPCADVRVDELQRLKVNMRKFLEYGFPSRTSWEELGWSGRSIDSIMDNIISWISQRQNSGMKGLHISLGADNMPLIPPPLMVVESAMRTIDCQPDESLSHSVLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFW2</accession>
    <name>A0A3R7PFW2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003121">
        <property type="protein sequence ID" value="ROT65202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFW2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018536880" evidence="1">
        <location>
            <begin position="21"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="46153" checksum="82B2971B43294F2C" modified="2019-04-10" version="1">MWDQLFVLCSVWGRFHLLYCCHLPSPTATCCHLLPLVTCFHLPLAVTYHHLLPLAVTVLSPAGCHLPSPRHVLTSAVTYFPCQPNRHAVTFLTSVTSVTRPAHRRHLPLPCHLLVTCCHTTFPACPVTVTVSCHLCHFPCTTVTSCHVAVTYITSLLSPHRHLCHLAVSYIPLLSPNRHLPSPPVTPWSPTFPPAVDLTLSPSRSCHCCHYLTSRHLSPPVTCYFFPAVTYRHLPLAVTYFPLSPPVTYRCCTPTCHPVTSCHLLSTYRLTYRHLVPSPPVSLHCHLLSPAVTYLPSPTVTSCHLLSPTFPLCHLPSPPVTSCHLLSLAVTYFPLPPTVTCLHLVTTFPAVTYRHLPSPPVTCLSLAVTYFPTLSPNRHLLPLAVTYFPLLSPTVTCHLLPPSPALRFPPNLLAMITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG11</accession>
    <name>A0A3R7PG11_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoglucomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000144">
        <property type="protein sequence ID" value="ROT85966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG11"/>
    <dbReference type="STRING" id="6689.A0A3R7PG11"/>
    <dbReference type="OrthoDB" id="8300170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745:SF1">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745">
        <property type="entry name" value="PHOSPHOMANNOMUTASE 45A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase C-terminal" evidence="4">
        <location>
            <begin position="99"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT85966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="19425" checksum="E2018050815D7499" modified="2019-04-10" version="1">MLRNTDRFTCKCLTQPTLYGRMLHFFNCLSHWVRESSTIEIAATVTDRPRSSRSLLEQPATPLSEPITTPDSRLALQAANHTTARYDSAQPDNRAILPVSASSQMVTFLFSNGCVLTLRTSGTEPKIKYYSEMCAKPEQLDWAALEAELADLVECVVQEMMEPQKNNLIPRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PK15</accession>
    <name>A0A3R7PK15_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">limulus clotting factor C</fullName>
            <ecNumber evidence="9">3.4.21.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_007119</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Selective cleavage of 103-Arg-|-Ser-104 and 124-Ile-|-Ile-125 bonds in Limulus clotting factor B to form activated factor B. Cleavage of -Pro-Arg-|-Xaa- bonds in synthetic substrates.</text>
            <dbReference type="EC" id="3.4.21.84"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.84" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001906">
        <property type="protein sequence ID" value="ROT74376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PK15"/>
    <dbReference type="SMR" id="A0A3R7PK15"/>
    <dbReference type="OrthoDB" id="6376138at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042381">
        <property type="term" value="P:hemolymph coagulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000120">
        <property type="entry name" value="Putative serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF12">
        <property type="entry name" value="TRANSMEMBRANE SERINE PROTEASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0353">Hemolymph clotting</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0768">Sushi</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018719074" description="limulus clotting factor C" evidence="12">
        <location>
            <begin position="23"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="13">
        <location>
            <begin position="267"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT74376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="55071" checksum="9DC7FE055F5706A8" modified="2019-04-10" version="1">MCLRVLLCSLWATSMLCAPGSASPSNLLSRLHFTEGVASPGSSPYIDLTALGDGPASALLGRVKASLDAPANGADRRDNSRSIPATRRGNAFAASGAKKSHMGVSEMLQRAIDDIVVKKDHTFASVLSHHLRFLEENFVGGEEDGELVDVEELLRFSEAGNSSSVYALPPISPSHYPSPPFPIPFTPILPPHSPSTPPPIFRNDPLTPLATPPLTPLTPLPLYPLTLLPLLPLLLLLPLLPLLLLPLLPLLLPPPSGCGVKNVAARILGGYVAGVGEWPWQAALVHAPSGRTFCGASLLNTRFLLTAAHCAAVRVWLGAHDVSLQQEEGRVVRGVTHAILHEGFNSRDLSNDVALLRLDEPVAMSRTVRPVCLPDVQEWDEDIAQGKSDDAGVVTGWGLTAERGQPSPHLLQVSLPFLSVESCKERYAGINPVSANMLCTLHHFKDGVSRDSCKGDSGGPLVTEGENGRWTQVGVVSFGYGCGRRGYPGVYTRVTQYLLWIYLKIVQMEISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKV5</accession>
    <name>A0A3R7PKV5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative tigger transposable element-derived protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006338</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001808">
        <property type="protein sequence ID" value="ROT75142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKV5"/>
    <dbReference type="STRING" id="6689.A0A3R7PKV5"/>
    <dbReference type="OrthoDB" id="6336277at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF26">
        <property type="entry name" value="TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="4">
        <location>
            <begin position="78"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="613" mass="70562" checksum="26E3C1179CB3B0DD" modified="2019-04-10" version="1">MACPNERFLRSRSDPTGGGRMLSLDTKLKILERLSKGEGTASIARSFGLKESIIRSARKHGLRIRHTSQGPSSAPTNRRRRIKGPHLHRIERELACWIEKQNRLQISIDVTAVREKAVALHRKLQEETCSLSVLQEKFVASPGWFEKFKIRQQVHESYSCSDLENDGDDFLEIKHEPLEIYISEDESEKNISGTSYHDVMYDISQDNTLGPVIMTCEGAYQSQIMFPGNTRAESYLMQLQQVVQEGGYTPDQVFYASKTGLFWKRLPSNTFISKVEMSSPGYKARNDRFTLLLCTNMSGNLRLKPLLVYHTVKPRDLNVTSYQMLPVHWRFDRKASMTTMLFEDWFVNCAIPEVSAYCKMKNLEEKALILVDSVINQPELVNEFHPNIKVMFLQSNISSLLQPVDQGVIAQFKRIYTKSLLQKLMFFTEGRDEELVESFWSNYSMKEALFNIRDSWMSVEIPVFNEIWRSVCPHSIHDFVGFPNITREIQEIIELANKIPGRGFAEITEDDIMEHLESHMEELTAEEVAEQVKASQEDDDDQEITAASSMLTSSELKQVIKVLYETEQVLIEKERNPFRLEHSLPHLKSLKAIYIDALKKTEKRQSGTSYCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMA0</accession>
    <name>A0A3R7PMA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neuron navigator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002340">
        <property type="protein sequence ID" value="ROT71130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMA0"/>
    <dbReference type="OrthoDB" id="2161974at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="905" mass="97338" checksum="3B7609694E1F35B1" modified="2019-04-10" version="1">MYVRRAPWPGRAGEALRGQRVSGDDGDLGSPRWREAIYPPLFSAFLLPTSSTRTFRGLPARGYSSAARMRDRAFELARPVVNLRRGCYRSFQLGRETAYKPRQLREHSVLGSPFPLNICDAKRHSAKTRYFRPANDKISEGGGESRKHRPRREARNVSICLTVGSHPLPDEDDTRSKREIQEEEALNRAPGDRRSMGVGVQSPKVVPEPPPSSMVRKSWHAGSQLKTVASASSSRSTSPANGSASFIPQPRSHSGRASLNEKHSKTGGTSNLVKSNLRGPATQTAHNASGNHALASPYHATSAPPAKQKDSMLDKFKLFNHKEKEARNKTTSKSSSGVSKRTSSSSGFSSARSERSDSSTSLCSDAKPPPLPPHQSLPVSTSSSSSDQTSHAEAQQGGAPPASTKPQGLRGIRSKFSKSAGKEGKESPKASRKDKEREEREGSRGSPRGGHKTHRDPRGESRDRSAKKGDKLTLELDGGSRPQRPQCPLPANAEKDSRPPAPGPRPETAGHAASESDQPPALPPKEKDHKEHSHSSHQDQAPAMQQQTVVTTPGSPLPPGTPGTGIPKPTAHVKGQTKVVPPERSAPPTPTASPNVNTSHQAKDYNKMVRPAGTPSTPKIGGSSAPRTAGTPSGGEANAAQECRDPKGSLPRQKQLGRREDSATGISVAMVSPMPNPREKDMVTPSESGSNISESSQSNSGHSNSTSSGNSSVIYKPTSSEDDSVSDLKTHMRKVEEKAEGEEGDEVILNIKPMQPLVRASQYGYMRGLGLHQTRTVPPSLHVSRLAALQDNANTVPQKGMRIGPHLKRPPGPNQVIDTDYSDLESVDLANEQVSVSCHGNGGHSKGPRDEVTRPPRIIASHVHPRELVFIPVGRESSRQSLFVSSHCAPCCVVRSWCCFKPRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PME4</accession>
    <name>A0A3R7PME4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002325">
        <property type="protein sequence ID" value="ROT71225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PME4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="666" mass="72491" checksum="5CD61499046C83E1" modified="2019-04-10" version="1">MLDRVLRCFDALHIARSQSAIPSENQDGDRGVVLYKDNLETVDSELWKHRFGAEDSRHNLFFRDFSLEEREFPESSAGSVSSAADQERIHVDPPDCSLEVQELSLCRSSEASNRTCHAEVSSTSSSPTPVTEVIITPPEGFRCDPDPSLSGDESSDSQGKPLEEQGENLSVSQTEIAGSLELIGTAVAHPEENVDDTVRSPINESENQKGTEPPTQTQAQEIATEATGTSEDKVPFRLITEREYQYHLKRIRKDSADEAGESEACKKPLSESIQKQESGEKQTFLKGENGSPKRLSNTERPSRVAYLKGLLFGGTENQPGTIASVTKSEDKGLDNSRTLHTKISSVDAHEVHRTKGSTGTHIESDYSSSSTGTPPPVNFTTHPLSSASSKENLLDEGNSDIKEAPLTENDDVVGDSTVCISSPENKENRFLSAQNESRFPLHKMYPDSDSESDEEEEADKNTKANVELAAISLESERSEELELFINNPESMIVGKVCISEEDTVFEEEEDANPGVTEGGEGDEASELIVFRLHVSEPSARTPSPSPPLIDGWGVDAGPTVSEELLSLEGEQFVELLPTLVKDELLTVSAQATGDPADGTTPEVKVPYVLISEDVRQSNETVTRADLDSCERWAVESRSGGFSSGLSCSIVSSATLFLCVPFLLLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN19</accession>
    <name>A0A3R7PN19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose-6-phosphate translocase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004089</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001545">
        <property type="protein sequence ID" value="ROT77269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PN19"/>
    <dbReference type="STRING" id="6689.A0A3R7PN19"/>
    <dbReference type="OrthoDB" id="3639251at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061513">
        <property type="term" value="F:glucose 6-phosphate:phosphate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051337">
        <property type="entry name" value="OPA_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43826">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43826:SF3">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="130"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="35304" checksum="D9A48462E55F5F49" modified="2019-04-10" version="1">MTRAFLWARPPPPRRRPRPGYTHPFALAALPRRCALLPFPRLSLLFALPVFLCSLSVRRVAASCSDRLSLVSIMMAGVSLVALVDDPSHAHLPDPTASSRPSPPTKPKQDKGVTNTNTNMTVRDLARSPFLWVVSVSYMVVFCSKTALSDWGQIYLIEELGRSQMQASSFTSAIETGGFMGGILAGVITDKMARKLRIVGNVRLMVAAGFMVACAVGLHLLCYLLSPQSSQLLVSAVGVLLGASMFGPISIYGIVASESFPAHLSGTAHAVVALAANVGAVVAGWPLSWVARTFSWNGVFLLLEILAASSVLLILLSRRIHVTLKAKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PR69</accession>
    <name>A0A3R7PR69_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001158">
        <property type="protein sequence ID" value="ROT80076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PR69"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000178">
        <property type="entry name" value="Saccharopine dehydrogenase-like oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="32"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="48987" checksum="5414644DA1C9D434" modified="2019-04-10" version="1">MFASSLNLARGSTRILATRMASLAPGQRYDLVVFGATGFTGQYVVEEVARVAEKERTERKTPLTWAIAGRSEKKLQSSLVEARKELGLSLDDVGIILADVKDNDSLKDMAAKSSVVINCVGPYQLFGEPVVQACIENGASHVDISGEPQFLEGMQAKYHKAAEEAGVHIVGACGYDSIPAEMGLVHMIKNFKGELNSAEMFVRTKSSKTTSVHTGTMESAALAVANRNEITRIRRELFPIPLPKPKHKIKKKGVLHKNEELGVWGVPLPTDEPVVYRTQRYRYEVLGQRPLQFQQFIGLRSPFQGVGLLIGMAYFTFLCFFSWTRKLLLKYPEVMTAGVFSRAGSDRESLKALRFTATLVGHGWSESLLDGSDQHTEPPNASIKVKVSGPDPGYGATSLMMVASAMTILREKSSIPGKGGVLTPGVAFMNTGLIKRMEDQGMTVEVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PS10</accession>
    <name>A0A3R7PS10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001072">
        <property type="protein sequence ID" value="ROT80766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PS10"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="706" mass="76403" checksum="4B3CE8C4EA872C88" modified="2019-04-10" version="1">MRTRRTIDPPSPGRPLLPAPPPSRTALAPYDKDPPALIPASASRIEPLEILLGSFLRSNPLISASPVICPIARSKANIITILIKPLACCSFASCRRGRVEDDLGLLSTTRQAPPDLKTRTLGHQSVDDVNALLIDQAEGEGKEEEEGEGEGGEEGEGREEREGEGKEEEEGEGREEEEGEGKEEEEKGEGREEEKGGGKGKGKEEEKGEWEGKEEEWGSPTNLRSSLPPSSLPLSSLPSSSLSFPPSLLVSPSSLPSLPFPPFSLSFPLLSFPFPIFPPSFLPSFSFSSSRLPYPSSFLLFSSSLPPPSSPLFPFPPSSLSFPRSFFPLPLLLPSLSFPPPSLLDPPIPPPFPSSLSFLPSPLILLLPSPSLSLFRCFLFSPFRISLSLSAFLSFDLSFSLLSDLPIFLPSPLLLPTLVVPFHFFFSLSLSSSFLFVVPHPLPSSTSFLLLPFTLFFSLPSPPPRLPSSSLLFALSLSSLFFFSSPLSLFPHLLSFSLSFPPSLCVSPHLLSSPPLLPSLLSLFSLPPPLFPVFLCSRFFSLSLFSSPPFSLRLPISSSLVSPRIPFSLSLSPHFPPVPLFCSPLSLSLLSLLLSSSPHTSPSFTRILFSLSPSLPLSRLFSCLLNSLLSPFLSPLFFVSPYPLPRFTSYPSFSLSPLPPPSWSPSLLPPFLSSLSPSPSSSVSLCLSSFGSPLTRHTLSPIPESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PS73</accession>
    <name>A0A3R7PS73_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nesprin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001052">
        <property type="protein sequence ID" value="ROT80892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PS73"/>
    <dbReference type="STRING" id="6689.A0A3R7PS73"/>
    <dbReference type="OrthoDB" id="6373308at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="253"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="355"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="64629" checksum="0018F8E3E0F55DFD" modified="2019-04-10" version="1">MNVGAYDCGRDLDRVSQASSEAKQLISKTKSHYITENRSLPPEIASQLSNLELEAESTEAKMDDQHVEAKRARTIRFEYNRDVESVQAWIQSAEAKVQDKTVEPHKLKEFLQEIHCEIGSVTDQLERLTRHGHMICQRTSNHNERELVATTITSLTEQLQQVRNWLEDKKAQVGDSLESWQQFIQLYNSLRSWVERQRNFLSEPLKFATLAEGRAKLQEYAAAVKDCKWASKQVSEMTSELAKISQISNVGPLTDKQAEMEQEKADVESSLKELMALLQEMTEEWEQCERKSKDVAGWIEKTRQALDNPQNKKRSLRDQLASREKALADVTIQKTKLVMAMEKLQVHFRDRMCAEAQVAHENELLQARLEELQATVKEDCKTLEACVHQMDAYQQEIQRLRQQMVRVEQELRVVSSPTYSPRDRDKAVAEQNIVSVVTNRTAARPQSEGEEGVRRRVRPAPLAGLRGARPRVARLGPGSAALTPSTDPANQKVRSCIDMQSCASVQLGSCGWLRRLEWRALRRSLSPSSRARASGAERPNTLRNIHVQSVNNPLTNSPKIKWIFTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSF2</accession>
    <name>A0A3R7PSF2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001010">
        <property type="protein sequence ID" value="ROT81159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSF2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="104" mass="11304" checksum="A9D8657EA14BF9F3" modified="2019-04-10" version="1" fragment="single">VSKDHLVHYPSTAEGEPALYTSTLGLTLTATSSLFAEGVLNLRCTATVHVYEWSTDVSLHLDNVTYSQPHHLPTLQQTDGATSAFSSCLLIAFSLFSFCVLRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PY24</accession>
    <name>A0A3R7PY24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA-directed DNA polymerase from mobile element jockey-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001093">
        <property type="protein sequence ID" value="ROT80671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PY24"/>
    <dbReference type="OrthoDB" id="250548at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33395:SF22">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33395">
        <property type="entry name" value="TRANSCRIPTASE, PUTATIVE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="139" mass="15762" checksum="871A813269013650" modified="2019-04-10" version="1">MAELEREIEGLSERKRRAYHRYMDKLNGKKKKKKQQVQEKNDGKDENPAAMNSKNDNRPYPPILPLDIMTNGILKLMTTLDTNKATGPDQIPALILKSCAPVLAPILQSIFSQSLASFTLPNDWLYANIDPPLQDSRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZ12</accession>
    <name>A0A3R7PZ12_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Ionotropic glutamate receptor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_018121</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003348">
        <property type="protein sequence ID" value="ROT63987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZ12"/>
    <dbReference type="STRING" id="6689.A0A3R7PZ12"/>
    <dbReference type="OrthoDB" id="6382689at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018677137" description="Ionotropic glutamate receptor C-terminal domain-containing protein" evidence="14">
        <location>
            <begin position="18"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="686"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="15">
        <location>
            <begin position="344"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT63987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="727" mass="81315" checksum="8EE3CB26D9C3CF4C" modified="2019-04-10" version="1">MDLKPVWILLVLGASAASRTSSQARGKGIDSPAEGWDLATFLNNYVQLQGFNSVHFLRDSNGLNREIRSLNLKHFPRFELLENRGRNRLYTSEPKSAYIRHISYSYVRRREMVQYSSCLKYKRLSTSVPWEQWWSFGYRHFLRAQKEAYVALSSLADVSQVVDRQLQPSGESHSENVIVIFARLFTDSDFQILSAVLNEKRFQSLHWLFLCLAPCWPRLGYVGFPLDNMAVVAEVSSLRPGAEVAFWDVYQPAPHLPQRASVVSRWLLRDLLCPDCPGNATSAAGLPGREEEGDGGGGVALGFPREPWARRTNLTGLVVRCTALPGAPHTYLQDTPTARQDLRHLRRAVGRPERHSEFHLSILPSQSPFRQRCTRPPDGGWGALRNGSWTGMIGELVKGEADVAVAPLDKTYIRSLVVDYPHPLSLEGYVIVIKRPQGSSSTWNSYLREFQPSSWLVLCAVLAALTVVLTFLGRLSPDETAMSAGDAVLVTIAALSQTGTDAVFSSISSRILFITLYLTCVLVYMFYTSFLISALTVNKVSLPFRDLQGMFEKKTHTFGFHGGGSLEDFFKMSHIQRNRDIWNEMIVPNPHSLQKMEDGLKQVLEGRHAYMGNKIFFLSTLYHCGFYILPGDYFLVAKTWPMRRGSPLFPVFNHHMIAMAESGLVVKSSRRWMPRGASCESSSVDAIGLATVMTAFLLLGSAAALASGLLLLERLCYKKGSSRSVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2U0</accession>
    <name>A0A3R7Q2U0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="1">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="1">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002855">
        <property type="protein sequence ID" value="ROT67064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2U0"/>
    <dbReference type="STRING" id="6689.A0A3R7Q2U0"/>
    <dbReference type="OrthoDB" id="2015551at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0186">Copper</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Superoxide dismutase copper/zinc binding" evidence="2">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="127" mass="13345" checksum="2B8C348CCB7E3FE7" modified="2019-04-10" version="1">MVFPPIYVTGRLTPASTASTSRLRGLGRRLQGRRRPLQPLRSNHSAPDAAQRHVGDLGNILAGEDSVAYVDILDDEVTLFGWYSVLGRAVVVHAGEDDLGLGGDSGSLSTGNAGGRVACCTIFAVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4M8</accession>
    <name>A0A3R7Q4M8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000112">
        <property type="protein sequence ID" value="ROT85981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4M8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="591" mass="64078" checksum="FFC7D752243B73C0" modified="2019-04-10" version="1">MPKIPTPHHSTTCKSHPYPTLSRHMPNPHPSHFPTLPRPHPSHSHSAKSPPLPLPTLPNPHPPTPHNSAQIPTLHTTRHSGQSHPLPAPPTQAPKIPTPKSPHSPHSLMRLTLPLPHSAQILCSLFHSPISAKSPHPSPPSTPRTLQWYPLCQLPTPYYAKFSAIQTQRLYITSTYTPLLHPVTSSLSNSPLHTCVSVAVWGFTLYSPSSPFPSPLLLSPFSRAPSPCLATPSPSPSYTSLSFPLLALFLSNPGSSLFPSPSPCYSPLLSFTLLLSLSLPSRCTHPLLLRALRLISPLFPSLLPPILLFSPSSPLPLIPSFPFSLTLPHLPYLFSFLPHPSHFNLLLSTSPSPYLSLFPLLPHPPILPLSPSPSPSHSPSFPFSLTLLLSLFPLIPYLLLLPLSPHLHQAAILAAPSFPFSLHPPTIPLILSPKSPTTLPSFLLLPHPSHFSLLTTSFTHPPTASRLSPSLRSQVLPLSLLSPLLLTRPLSLLSPFPSPSDHSPSFNIPHSHTLPTFSFSSPPTLPLFSFSLTIPLSHLFPFSLTLTTHSPSFPLLSFSPPTLPLSPSPSPSHSPSFPLPLTPHSPSYSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4R4</accession>
    <name>A0A3R7Q4R4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">enoyl-CoA hydratase</fullName>
            <ecNumber evidence="4">4.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_013332</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002659">
        <property type="protein sequence ID" value="ROT68531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4R4"/>
    <dbReference type="STRING" id="6689.A0A3R7Q4R4"/>
    <dbReference type="OrthoDB" id="10004768at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016507">
        <property type="term" value="C:mitochondrial fatty acid beta-oxidation multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016509">
        <property type="term" value="F:long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000011">
        <property type="entry name" value="Fatty acid oxidation complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050136">
        <property type="entry name" value="FA_oxidation_alpha_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43612">
        <property type="entry name" value="TRIFUNCTIONAL ENZYME SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43612:SF3">
        <property type="entry name" value="TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT68531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="317" mass="34384" checksum="ACFAB2962BE6427A" modified="2019-04-10" version="1">MKLPEDYSSLSWPQQSASGRRQRRFEERRWQAFVLSGPSSRQSSRLLSTTRAAMGVHANLKINDGVGVVTFDSPGKVNVLNQPVMEEIVKIVDEIETNSDIQAAVLISGKPGCFIAGADITMIESCKTAEEAQALSKSCQDILFRIEKSKKPVVAAIMGSCLGGGLEVALSCHYRLAVKDKAGLGLPEVMLGVLPGGGGTQRLHKLVGVPGALDMSLTGKTVKADKAKKMGLVDGLVNPLGPGLQQPDLRTLAYLEEVAIKTAKDLASGDLKAKRGPRTSWKRQWERLCSMTSSRTRYSRRLVVRSLSRQMDSTQHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q616</accession>
    <name>A0A3R7Q616_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012297</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002558">
        <property type="protein sequence ID" value="ROT69500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q616"/>
    <dbReference type="STRING" id="6689.A0A3R7Q616"/>
    <dbReference type="OrthoDB" id="6380544at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="445" mass="46906" checksum="C1F61D30892C16F1" modified="2019-04-10" version="1">MPPPNMPRPSGPASLFDFFDVKMHEKKETVNFVEPVADVRGSAYQTGRGGRGGGREGRGGRGSRGRMLSRGGAVNGRSTPPDLASENWPAPGEEKNTPTSNRSYFESKELMEEKEQEDNLALRHHQLQTSALGRDSAPIAYRNDHGGQYGGYRDSGRRDYGGGGGGSYNSQDSRRTERGGRGGGGGRGTSGGYRGRGGVGGGSGGGGGYRDSNSNPRGGRGNSNSGYRGGTNSYREDGGNSNFYRSDGGGGGGSNYRQYNGANGGYRGGNSNYGNYGDSANYGGAFRSDSGSNYRDSGGVSHNDSSYSSGYKDMQGSRSSSNQYNPRYESYSNRQGGQNSYEPNLGGRNGMGGGRGGSYTSGRGGGGSGGGNMQASNSRTSKEMRLIQDFQRSMTLAGCYPQEMMNYGRYEDGAEYADFSGTLEFHRGGGSGRGSQRRGGRGAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGU3</accession>
    <name>A0A3R7QGU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Focal adhesion kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002878">
        <property type="protein sequence ID" value="ROT66921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGU3"/>
    <dbReference type="STRING" id="6689.A0A3R7QGU3"/>
    <dbReference type="OrthoDB" id="9976756at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005925">
        <property type="term" value="C:focal adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007172">
        <property type="term" value="P:signal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000039">
        <property type="entry name" value="Focal adhesion kinase, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.330">
        <property type="entry name" value="Nucleotidyltransferases domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036137">
        <property type="entry name" value="Focal_adhe_kin_target_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005189">
        <property type="entry name" value="Focal_adhesion_kin_target_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46221">
        <property type="entry name" value="FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46221:SF9">
        <property type="entry name" value="NON-SPECIFIC PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03623">
        <property type="entry name" value="Focal_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68993">
        <property type="entry name" value="FAT domain of focal adhesion kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="495" mass="55514" checksum="5B5CE892640B10E2" modified="2019-04-10" version="1">MYRARDGSNVPVAIKTCKVESEGTMAEKFLEEAYIMQQFDHPYIIKLIALTALSYLESKKFVHRDIAARNVLVYSHDCVKLADFGLSRWVEEQSYYKASKGKLPIKWMAPESINFRRFTSYSDVWMFGVCMWEILMLGVKPFQGVKNNDVIKRIENGERLALPPNCPPRLYSLMSNCWMYEPMKRPTFKHIKEDLSEILREERAQQHETMRRENRRVQGMSWGSDEPPPKPSRVPMTSGGRGHTATPPPPSGSGLGSPPLYAPSQRQGSHQSDSGDMMSGAERKRMSFATSASDKSDSDSESPVTHHPPSSPSPAQSEEIRERSATPLSNGSGSAVEEPKIVVKQVEPTPTADLDRSNDKVYESTIHVVKAITALTHDVKEGQAHVYLDHVKKVGHELRDLLATVDTLMTAIPPSSHREVELAHKVLSKDMTDLVQAYKLAQKYGSTTLDEEYRKRMLSAAHVLAMDSKNLLDVIDGVRIRHGLATYLPSKHSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QN69</accession>
    <name>A0A3R7QN69_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008759</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the THOC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002104">
        <property type="protein sequence ID" value="ROT72837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QN69"/>
    <dbReference type="STRING" id="6689.A0A3R7QN69"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001007">
        <property type="entry name" value="THO complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040132">
        <property type="entry name" value="Tex1/THOC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22839">
        <property type="entry name" value="THO COMPLEX SUBUNIT 3 THO3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25174">
        <property type="entry name" value="Beta-prop_THOC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="90"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="218"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT72837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="349" mass="39905" checksum="BAF15FC794370079" modified="2019-04-10" version="1">MSQQHGEGAQCKQTERKGKMGSSYMAYFEEMKSYFQTHNKQKEYIGHNSKVHTIGWNADGRRLASGSYDKCVTIFVFDVHRETLRKDYTYKGHGDSVDQLCWHPTHSEQLTSASGDKTVRIWDTRTHKCSATINTKGENINITWSPDGQTIAVGNKEDLVSFIDVRSQKIRHEQQFKFEVNELSWNNANDLFYLTNAQSGQGYIHIYNYPEMELVHSIHAHPGNCICIKFEPQGRYFATGSADALVSIWDAQELYCKRTLPRLEWPVRTLSFSYDGQLLASGSEDQTIDIAHVDTGERVAHISVAYPTFTLAWHPRLFLLAYACDDKDDRERDRDAGTVKLWGLSGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVR0</accession>
    <name>A0A3R7QVR0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001165">
        <property type="protein sequence ID" value="ROT80021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVR0"/>
    <dbReference type="OrthoDB" id="6369181at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="579"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="607" mass="65968" checksum="4BDDC41F6143F49D" modified="2019-04-10" version="1">MEEQSDLIVGHSHEESVRGRGNTAVSLVMEGQCGYIYGCCCPLVAGDVMSDRGHHITSPADLIRTGEDTCFNNVLMYLTAVAAMVRSRGMSNSTPAPYGNSWCCVRRGFCAIASQINTLGSFSFVGERLKAPSAPAIARIQAPKGPASHISCGRAFTRVTWPVTAGILATQISQELSTVRRASRKRSNLTTKPSEDFELLPPLGNAPWTRMKPRRNHVLCLLLLMASGFLQDAAGEPIVAKCPPSDAEDTSNEFCKCDQNPSRSNRVITIKCKFNDKEDVLLTDELYPFRNQTLMTAYVRVENASSVHVTESFLREWQQAPSIALDVWRGGNLTLDPTPEHDNIKRFAPTRPSSMRYLVFEDTVVDKVVGSVATEGYVTLSKRELHSWIGLRLSNVSINSLAKNAFNLTHKHARDCGTGALTVAGDVSVTITGNTFQHLQKEAFKIAVTGDVKFDENVIKSFDPDALEGLVCHNHTSLERNTVHVGKFDGLALNASAAPFHESCGSPQLFMVVTPPASRVTSATAVATWLIGVILLVLVVALVAGVIYTWKTQGLVLRYYTGRGAPMYLNGRKSSQENLPNSAEISANAEAAETGVSNPMYNTTAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWF6</accession>
    <name>A0A3R7QWF6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001078">
        <property type="protein sequence ID" value="ROT80730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWF6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="606" mass="68521" checksum="0F15D37CA4406158" modified="2019-04-10" version="1">MSGAPHASPTSFLLTCQTSVEHPRIPFPCPFPLLMGLRFLLIFRQFLRLKIAFPSFSFYCHEASEVFFLFSKSLSFPWPKLPSPLPTNSASSTSRKAPPFPSFPPSKLPSDSPPHYLNPSPPYSLLPQIHPFPLFSPYKPRIPYLFPSPYPATYPYPYPPTYPHPPYPPHLLALNPQPFSQNRRRIPFLSICLHYSSFFPSILLSFLTPSSPFSVPPPPSSLSLILLLSSCPFSLPLHLHLIPLLSSFLPLLFFSVPPSSLLPPHPSSLFIPFLPPSLSPLPLLPPPPFPSPLPPPPFPLPIPPSPIPIPPPPLPIPPPSSPPPLPLHPIHPSLSLGESLFHLNARVESCNWKLRGNAVEGWAKRGKREKRRTDRKTERGIEREREGGGGWGREGRRGQATSRLFPKRKQRRLFELFPFPKFPKATSRYSIHTKPKPRAVYSPTSNHTKPKPRAVIHPLFPIPIQAKRAVIPNPPKAQARAVIPHPHASHSRYSPIHTKAKPRRYSPTNVTQSTRNPSHEPLFPNPHETPRRYSQSTRNPSHEPLFPNPHESQATCRYSPIHTKPTTSRYSPIHQRKPSHMPLFPSIRNLKYSIPRLMLSFEMQMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QX83</accession>
    <name>A0A3R7QX83_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Mediator complex subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED8</name>
        <name evidence="10" type="ORF">C7M84_025298</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000958">
        <property type="protein sequence ID" value="ROT81533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QX83"/>
    <dbReference type="STRING" id="6689.A0A3R7QX83"/>
    <dbReference type="OrthoDB" id="150687at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13074:SF9">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10232">
        <property type="entry name" value="Med8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0010">Activator</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="85"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="135" mass="14677" checksum="B17E055CAEB11837" modified="2019-04-10" version="1">MLRTKPEPDVEKRHLTLEAKMAQINGDTAQKQINVHNKVVKHVMDLVNTAREEWETETASRTNQPQTCSNSETEVLLAALGTGKGIKMMPGRAPPPGPSPTIPQQPPPQMPNTSKAVSSVKTNIKAASAMNPYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SKP1</accession>
    <name>A0A3R7SKP1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_017130</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003168">
        <property type="protein sequence ID" value="ROT64925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7SKP1"/>
    <dbReference type="OrthoDB" id="6356350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="11">
        <location>
            <begin position="636"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="12">
        <location>
            <begin position="1127"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="381"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1064"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1412"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1431"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1443"/>
            <end position="1456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1503" mass="168294" checksum="EBDE92E8441A77C0" modified="2019-04-10" version="1">MPSDVATPAPPTPADSTARLQPLSTIVRFDGSDRITVDAMLRETEEYVAATYPALSDRSSSEFSDRCLQHVLQRLDQTSVPVRQVLTAFEMSKNRTWDDFKTDFRLTFAPKDVPPFLQTARMFNLRPASFSPIDLHLLGANIRSSFDRMTCALRSSPNFSYFKPIADAIDANYNIFQTYFTLSTFLSALPHGQQETVLDKMQLPKMARDVPNAFLKAYAEAPNFTPARTLLTATVRTVDDLIAGDAPLLPAVFEGRPAYFFVDSGSAVSLVPLSTLVNFNVLSPVCPSNWCVRAASGTSLKVMGEVKLNIVLSGKNYAFPFVVVDDAHLPLLGYNFMHKAKLRQQPDRDTVTHQGYVYRLTTPNSVWHSSSNPASTIAAVTSTIEPPTVDPTPDDSPKDDRTRRSPFAISTPAQDLQDRCHTTTTTPNVKTSRVTDSPFSWAPQTEASACIVTTNLTLPPFTDSMVPVRVTSTDGTALITPDCIRVKGLCALPAIYEVTNGTSALHLINATCTPVRLRRGTRVCDCEVTGLPVVEVEPPIAPVCNTSATMSAPDAPGPEETLCEFPPMDFAEGDVLRRLLKEFPSLLPTKDRPLGRTDVLRHRIDLIPGTKPIYIPSYRIPHSCRAAFKEATDALLAQGIIEPSQSPWSAPMLLVPKKDGSLRPVIDYRRLNAATVPDRYPIPTIRTLLQEVGEGHAIFSSIDLAHGFLQVEMDPSSKDLTAFSTLNGHFAFTRMPFGLRNSPITFSRLMSLIMQGLIGDTAFLYLDDLLIASKNIADHERKLKLVFQRLADANLTINVKKCQFFRKQTEYLGHTVDSSGLCPNDKKVRDVQNFPVPSTVTQVKAFLGLSGFYRPFIEKFGIIAEPLTRLLKKDAPFTWTGEQQQAFEILKQRLTEAPILSFPDFNETFYLATDASSIGLGAALMQRHDGRYKPIAFASRKLKQAESNYSVTDLEALAVVWALKHFREIILGYNVHVLTDHRPLKYILTDSKHVKGRQARWLDTLLEFNPKIDYMPGSANKVADALSRNVSVNHLSVLSPLELQAKQRADPLYADIIAHLEDTTKPRPTNRYRPSKNSTSVTAYSSGNQLLRNCVDPNNVVRTKLVIPEVLVRTCQKLPDLPPLQGTHCRPNARTHLRHTRTTLRQKNRNRYLLVMIDSFSRYTELAPIPDKSAQTVTRTFLSHVICRHGAPEQLMCDNGTEFANQVLKGLCKLLNIDLVHILPYRPQANGLVERLNRTILNVLRTTINTQDNEWDLWISITQAAINSTFHSSLGDIPNYVVYGDDQRLPYELLQQRPSPVYGDDYAKIMIAREQEAYRIAREHLRVERDRIIAQQHKLARRKEIAEGVLVFHRVSAKFSPMPKLAPDFEGPLRVLKVRHNKALCQNLTTCSQTWYHFDTLKLASTHYEDEYDRQRSLTRLTPTDIAPESTPATSMTQSSPEHLQHRDGHHMHPETRSVVGHATPTLLPTRINAPRRDQTPCVTCQDFVFSFTHCSPIEDDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQX7</accession>
    <name>A0A3R7SQX7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_010482</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002330">
        <property type="protein sequence ID" value="ROT71214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQX7"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="538"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT71214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="559" mass="63405" checksum="D2698BB2BD60A7EE" modified="2019-04-10" version="1">MNRDQERQKRNERFQRRRNLQSSSQPTSRDPSPSQASSELHQLPVVTGGSNPDRQEEMLREQRQPEDRAERDDQQQALVVQREEEIQQLRRQLHQRTELEEARHSQSVRDAAPTDAAPLQVTERDEIRQLRRRLQELEGELASSRLSHVSPRTSQVGDTIRPPPVPPQPRPRSRPQTPEPVDRPLPPQSQSQQTTLPYPPYRSLPERIPTHHSRGTFLPGAIIVHLRCFHASCSSNPPVSYVFTKEKVPHFKGDVSASQPLKRNQEIEGWIRAVENIVKPPTSEAYIQAARANCRGPAELIINSPLFDNINEWEAFKAALRSKFRGTYTSSDFFKVLYENRMLPGQAPMDYYLQLEGSVYQGYRDHRDAIGDPAELVRRVFLSGIPAWLRDFLAVREDGNPTQLAETAQRIWNSRNGIHHGDHSSMSSGQFPERPPRGRDHYALPVSAEAPAMHSIFPVTAQGKWCSYHRVPTHNTSECRAVASSAPNSPPRRLCFQCRRPGHLAKECPFQQSQGEGAPTAPGRVGAGSMQSTSHTSQEVDRHNDNSRANRTTTRGTQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVY0</accession>
    <name>A0A3R7SVY0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001454">
        <property type="protein sequence ID" value="ROT77946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVY0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="421" mass="46204" checksum="B58F385661E654C6" modified="2019-04-10" version="1">MFVVETARAIAGHRNASDPRRRPRGQPRAQSIDLAARVKGEVYKKVLQQALAHTRGTYKQLVSSAASSSVKEAMLRQWLGFVTESDMALRVLYSLKDEGQSSLQTEKRKMETGDSKNKKETPQPRTLSHDSESYHKRKELEDQPIPTHSDLGRKTTGRDLISLLMGTLLEISRSSNSSASNRSRRSDQGLMYLPIGGTTKVNVMLPPPIPGRKRRASSFRAKWQNEAEASGLDLSRWAESKTGEQELEHIRLDIDKKQGVETSASADGDEALVKERSSKSESKVVRTELRTAKATANRKEAMIVDNAQGSAVPTADSNSTDAKTPPAFEAVTEPSVGDTIEDFSRPTPVPGALGSRSPDTRSSSRGCGKGGRRGVASGLLRAVREWALEAPLLPLQCRGLLWCRGLREASTQDVWLHVLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SXG2</accession>
    <name>A0A3R7SXG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SXG2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="148" mass="16274" checksum="6F4689D432F7BED1" modified="2019-04-10" version="1">MAIFRPVQPEAESVLTIDQSQHAPSHPSASLYTSDTKNIEGNLYTPKVEEVKKIRVATSPLDLSRVSKKEAEMENTQPQYSPRSSSGESLDSPRSNGESADASNTITLVTPAVVTKIISPCHVEDDDEPQIPWRTNLRKTNSKLSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T092</accession>
    <name>A0A3R7T092_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Crustacyanin subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T092"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="195" mass="21963" checksum="CFD7AD439AF083F8" modified="2019-04-10" version="1">MFTTLVAAAPRALVSADGIPDFVVPERCAKVANQDNTPAAGIRPQIIDNAYQPYTRCIHSNYDYSDSDTGFKVTTAGFSPNNEYLRLQGKSTPQGLPCCPHAHRFSYRYFFAAPYEVIETDYETYSCVYSCIDWNGYKSEFGFVFLPHPTDFRSSEQRQVAPSVFRKNGVDFALFNEVAHTGEMRLQSLKFTSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0A9</accession>
    <name>A0A3R7T0A9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000631">
        <property type="protein sequence ID" value="ROT83875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0A9"/>
    <dbReference type="OrthoDB" id="6368632at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="583" mass="62308" checksum="3D5B5E0758EA3660" modified="2019-04-10" version="1">MTSAPPPIVSSQEKKVLGMSVEGMVLHTLKTLESTSTSGITPTSTTSMDWVSEPHESTRGQASKVYTPLLLLPLRACSWKSCTSRSSWTSHSSEVWRARSRTSSSETDASTLRKRRRVNLTLDFAEACPEEPPLSPASQEDLRRTSATPSRANSEDAQLKLHHRKVSTPGSALSQPGSGGRRLRDTLAAISTTDVSVTLQQLLPARLRAAESHNSISSSSKGTTPSSSPSIFQKRSFRFSSLHKKRSKSVHDQINSSGSTPNISQSRNDLASCEEDIVAFQRQLQNLPSYELMDAPDLQTPPPFRQRSRSVPRVTFESMSTLLVPRPTPIGRSPTTTGADFNTGLLSTHLTLPPSPHLSPTTHLSPHHFPVPHLSPSRSAHNIASSTPLHSPGMASPHNLASPASSHVSQGSPRPSSPFLSPGSPYSPHSLSSPRLRSPALSPITPPRFPPTLAGNVDDAPLSALPSSLQAGGEDLRGVASSRSSSVTPTRYRRFDSPVYIVVDIPAVHRAVLQCVEEWLQSGGVQVEGNPTVARELSEFLTRVAQCGAPTSSGATTCDPTGTSRWVGTPCGDGERGDGGDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAS2</accession>
    <name>A0A423SAS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004243">
        <property type="protein sequence ID" value="ROT61318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAS2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="344"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="46794" checksum="660AE2501587CA66" modified="2019-05-08" version="1">MADSLQDYSSSEVSSDYSDEDIGMSSSEGAYVFEELEEEEYQGLMVVGPYMHEPDAVDVVEVVPNQLDMEWRRDPKRMNEWPTSIREWRVTEIQEGASPSASACVYPERLALWSRGGVPLTACSSPSTDEDSKHGESRVRCGVVCGRCYFLGCRSFGTVAASVFLLCLLVGSSFAGDYGGRTSGRTGSRGNNFRRGGDFNDDFNRDRIFGGSYRRNDNFNRFGDDYDDNRFNDRNDRRYNDFDRFDNDFRGRTRGSNDRYDRNNDRRDYNFDRFDNQNNRRFDTSNDRYNDNDRFDRFDNEYSGRTNRFDNRYNNRNRNSFDRSDNNYSGRTDSFNRRSDRFDGFNSGSFRSGSSYSGNNRNFGSNRNYNNNNFGSNNRNFGSNRNYNNNNNGGSLSGGYLPPVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBM1</accession>
    <name>A0A423SBM1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein kinase 1</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_020614</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Host cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01004091">
        <property type="protein sequence ID" value="ROT61587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBM1"/>
    <dbReference type="STRING" id="6689.A0A423SBM1"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030430">
        <property type="term" value="C:host cell cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14005">
        <property type="entry name" value="STKc_PIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051138">
        <property type="entry name" value="PIM_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22984:SF25">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22984">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-1035">Host cytoplasm</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="67"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT61587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="347" mass="38520" checksum="D0FAA68CE95BBA77" modified="2019-05-08" version="1">MAPQSSSVAPPVFCSDEKATATSCKMCSKCGPIAATTKPATSNATASSRVTVPLTTRGNGRPVEETYRVGPVLGKGGFGTVYSGWRVRDGAPVAIKQVAKAKITAWEMVGGRRAPREVALLLRVAHVANVVKLLDWIERDDSFLLVFERPEPCKDLFDYITERKVIPEAEARSLFKQVVDIVRDCHAAGVIHRDIKDENLLVTYDSKGRPVLKLIDFGSGALLSDKTYTDFDGTRVYSPPEWIRYNQYEGVPATVWSLGILLYDLVCGDIPFEHDEQIVAARVHFRSAVSEECQYLVRWCLRVRPTERPSLDSILQHPWLSPPPPPRIRHPDQASLDKCSTSSQESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCN7</accession>
    <name>A0A423SCN7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-amylase</fullName>
            <ecNumber evidence="3">3.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020239</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1-&gt;4)-alpha-linked D-glucose units.</text>
            <dbReference type="EC" id="3.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003912">
        <property type="protein sequence ID" value="ROT61949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCN7"/>
    <dbReference type="STRING" id="6689.A0A423SCN7"/>
    <dbReference type="OrthoDB" id="550577at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004556">
        <property type="term" value="F:alpha-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031319">
        <property type="entry name" value="A-amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43447">
        <property type="entry name" value="ALPHA-AMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00632">
        <property type="entry name" value="Aamy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-amylase C-terminal" evidence="5">
        <location>
            <begin position="394"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="686" mass="73766" checksum="BB9E73E3ADA5CD37" modified="2019-05-08" version="1">MMDLTNDLNPAQGFPPTPAPFSTWSQKIAWGVQNPGQLEGVYDPGWGMADPDKAFVFFLEIHTAETFKKPNLLTLPPSLFPSPCLSSPFFLLPSLHPSSLSLPFLPPLPSLFSPLPPPSPSLPPIPLFLSSLLSPSSPPSIPLFPPFPPSPLSSLYLLSPSLPSLHPSPLPSSSSLPPSLSPFPTLPSLHPLSPPPPIPSLPPSSHPLFPPSPLFLLPIPPLSSHPLPSLPPLPPFPSPPSLPPFPIPPLPPIPPLPPIPLFLIPLFPPIPLSFPSIPLPPPSLPPSHPPHPFPSSPSPRTAGDTLTHKFPKDYRLGVAFTLAQPYGFARVMSSYAFGDDSDAGPPHLSDYSTANVVINSDNQCDGGWVCEHRWPSIYKMVRFSNAVKDTAWWENYYCDGNVVAFSRGDKGFFAMVKYGTVSQTFQTGMPAGTYQDVVSCQEVTVNGDGSVHISITNEEEPVFAICVGCDCSEPPVVTATPGPETSVLMGPTEPSITEGIHRTVVFVQKQTNDGQDLFIRGGIDAGQRPGCTSDVATDPCAVDMTTSSLGATNHYDKYNAWRQGDSRSTGWAPSRARRLLWGRRLGNAPGLDLQQPGESSFGDHYWMVDMDMDCAQTEGGWFELKAFLTNAGNGWEADIIQVGSCSGTAGGAAPYASNNHLGRCGYVNVFTFDSSDCVINSFPDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEG0</accession>
    <name>A0A423SEG0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003621">
        <property type="protein sequence ID" value="ROT62573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEG0"/>
    <dbReference type="OrthoDB" id="6379939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301:SF12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="42380" checksum="6B3BBC54BE999529" modified="2019-05-08" version="1">MGVLHYTTRNASWNYSDKDCQGNRGRGTTITPPLQTSREDPTPTKVSEGESGTPARGTHTGGRDRGTPTRKDTTWETDTMVGQTIKEETPSGEQEEEKEDSGKKKIQTIGHGIGGAWPGRPVLSGCSSPTRPVDRLLTTYLTPLLDLLPERLQDTTSFLQKMRDAKRYPGAILFSFDIVSLYPSIPEEAAYVVANFYEQNFSYVEERLFSDFNMAAPPPYLIKEGIDHVLGGTLLRFNNRFFRQGKGTAIGASVSVAALRIKRIVSEEHKLETALQEMTGFFKARGYDNRCLNSALERVGNLQRDQLLIRKGHTLGNSLQDPPTNDSMEERKIDCREADQSAVPVASGRAQGVNEWQTTRLRYLKENRGGPRLPQSSKPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLH0</accession>
    <name>A0A423SLH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017021</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003154">
        <property type="protein sequence ID" value="ROT65023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLH0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="47546" checksum="AFBB9ED4DF5CBAE4" modified="2019-05-08" version="1">MKGDLDLTPTHTLGSPPSPKSLRRTRRRQPEAPRQEHAGDARETFLRPRKQGRVESSEGHTAVPRKPPLLRRDTPLHLPLPPLALPLFPPSLLTNPRQESHLANHIIPSLPHPPTSSKGSSFPRSSKSSLPPSRTLSLAPDIVPFILAISINPLTPPKPRGHSYSPGGLHADLKLHREERVARGAREGERGGPEPADQPKTDSRINQSQTPPPNRTCPPLLPPSPTKPRPGPSRRRRPTATPPCPLGLLSNAERGRGRLQALLARVVPPLSQCLDFTLYVCGTSPPAAPLLHTARLGILVNKSLRPPFPFALATDCAFAFHHHLSLIHSLQPPHHSTPPFPLFSSSLRPIPPPPSRLASRPLPSSPAEAFSRSRWRCQGGSTGTSRRITKASAPLTYLPGKRTPNYATSTHLPAFTGKPQIPHIAAPARHNHDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLL1</accession>
    <name>A0A423SLL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcription factor Sox-21-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003134">
        <property type="protein sequence ID" value="ROT65138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLL1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="558" mass="59222" checksum="820F6A3CDD6D9F0E" modified="2019-05-08" version="1">MLMGQKITDDISSASHRALHMKEHPDYKYRPRRKAKSLAKKDSRYHFQLPMFQPMLEGLRPFYPPPHLLAAHGAPGGSDKSPGELPRPLLPPPPMFPPHLAGLPYPSMDPILSRLSSPDALALSKLSSQDSLALSKMAQTESSLFSRLAPHDMFGLSRLSSPPLSSHLSASHGASSSGLPSSAAGPSLGSPGLSSPSAHPSSPSLTSSSLASPIPKYPPEVPVVSVMSRLPLESPYLGLTTRDLEHLRLQHLQSLERERRIREGLAASPPPSRSRSPSPSSPKIDVDCRSRESSPSRSPIDIEHPPSEQGAFRRFEDSVAHDEDPEASSSEEARAFTRYSERKSSETDAEAPPAKSASPPTTLRLPPHPFSPAALASSLYSHHHAAASPSAVVSAADLAFYSIRKANVSLFTGSYLGSCVYPSGAPVGYHHDPAGRPLLLPGAAGGEVPLRLPADALALLSLAALGRAVKGGAGVLVAPDRGGRRPRLPAPGLKLKEKRCLSHFGLASFPPTSFVGSRVVTASAVSIIPSGVCKIGVLGSRLISMTTTQECKRNFLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLP9</accession>
    <name>A0A423SLP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ADP-ribosylation factor-like protein 8B-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_016981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003148">
        <property type="protein sequence ID" value="ROT65069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLP9"/>
    <dbReference type="STRING" id="6689.A0A423SLP9"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904115">
        <property type="term" value="C:axon cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008089">
        <property type="term" value="P:anterograde axonal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000247">
        <property type="entry name" value="ADP-ribosylation factor-like GTPase 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT65069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="21195" checksum="4CDD2C76D9CE5DEB" modified="2019-05-08" version="1">MLALINRILDWFKSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKITKGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAADPEKIEASRNELHNLLDKPQLAGIPVLVLGNKRDLPNALDEKGLIERMNLSAIQDREICCYSISCKEKDNIDITLQWLISHSKSGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNG3</accession>
    <name>A0A423SNG3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_016235</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003037">
        <property type="protein sequence ID" value="ROT65788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNG3"/>
    <dbReference type="OrthoDB" id="37244at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000002">
        <property type="entry name" value="NAD(P) transhydrogenase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P) transhydrogenase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="27"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="NADP transhydrogenase beta-like" evidence="13">
        <location>
            <begin position="148"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="NADP transhydrogenase beta-like" evidence="13">
        <location>
            <begin position="370"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT65788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="598" mass="62445" checksum="F09A91E5F6EC6CBB" modified="2019-05-08" version="1">MKDALMYTAGLGSLVSLGIGSAAMTQMMTTFALSGIVGYHTVWSVTPALHSPLMSVTNAISGITAVGGLLLMGGGYYPTNVIEALAASAAFISFINIFGGFIVTQRMLDMFKRPTDPPEYNYLYGIPATAFLGGYAASAAAGYAESHQMAYLAASLCCVGALAGLSNQATCRLGNTLGIIGVSGGIAATIGQLVPANPVLLQMGGAAALGGAIGSTIAKKIEITDLPQLVAAFHSLVGAAAVLTCIATYLHDFPHFATDPAANAIKTALFLGTYIGGVTFSGSLVAYGKLQGLLDSAPSSSLAAMPSMLVSLLLILVPWLTTSSTHPSTLDCPCWEPPPPSLLSWVLTCLCDHGIEQLSLAGPSALKVSCLNNNLMTVVGALIGSIWCHPFLHVQSLPNVILGGFGTSSTGTGKPMEITGTHTETNVEQTVEMMTNAKNIIIVPGYGLCVAKAQYPIAEMVDILKKKGKNVRFGIHPVAGRMPGQLNVLLAEAGVPYDVVLEMEEINDDFPETDLVLVIGANDTVNSAAEDDPNSIIAGMPVLRVWLSQQVIVMKRSLGVGYAAVDNPIFFKENTNMLLGDAKKTCDALLTKLKEHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPF0</accession>
    <name>A0A423SPF0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Actin T2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015868</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPF0"/>
    <dbReference type="STRING" id="6689.A0A423SPF0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="367" mass="40940" checksum="9C24393DADDE0C04" modified="2019-05-08" version="1">MCDDEDQCALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWYHTFYNELRVAPEESPTLLTEAPLNPKANREKMTQIMFESFSLPAMYVTIQAVLSLYASGRTTGQVCDSGDGVTHMVPVYEGFALPHAILRLDLAGRDLTHYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFESEMNSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGVQETVHSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITCLAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQSMWITKDEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVM5</accession>
    <name>A0A423SVM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sidestep protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013597</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002698">
        <property type="protein sequence ID" value="ROT68269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVM5"/>
    <dbReference type="STRING" id="6689.A0A423SVM5"/>
    <dbReference type="OrthoDB" id="6346554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="18"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="207"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="306"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="404"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="6">
        <location>
            <begin position="505"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="599"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="599"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="674" mass="72854" checksum="700AF1F61ADCB742" modified="2019-05-08" version="1" fragment="single">SSRRTHLSLHVVELPGQPVLRVGGQRATDGVLGPLQEGTALAITCSVSGGVPPPKVVWKRQEKILDPTVESRSPTLTVNQLNIARLTRAFHNVRLTCVASNNNVTAPVEASITVTMNPASPYSSWRSALPAAVAPSSATEKAGSTLSLLRIFPAVVATAVWRLKSRVCQAGSPFARWLLCCERAGGIKDLRPRGAELHQELLGRHAPLVTRLEAPPKGLRVGREYEISCVSAGSRPHPNITWTLGSVASLTPITANTEHGVNMSTSRVRVTASRRHHGQRLTCTSLNPLFPAYPLSDSILLNVTYPPVATIELGRGVSSVVKEGEDIYFNCNVDSNPPTYKISWYHKGRPLLHAPDRGLLLSGNSLALRSVTRHQAGPYMCAASNVEGDAQSRPLDLSVNCELPVCSDDSSPSKVYATGLGQYINVTCTVKASPNVAKYLWVFNNSVTSERIPGDQVLKTPEGGSVVKFIARAHQDYGTLQCWAQNSVGRMTQPCLFHVVPAGRPDQPLGCAVVNKTYDSLAVGCTPGFDGGLEQTFLAKVFEAVTGRSQVNVSSRWPNFTLEGLTPGLDYIIQVMARNSLGNSDPVRLEAFTYKMAENRMRDEQEGHRGRGKSRGYAPPEKPGGGLSEGSQTGTVHPRADPTLHTSLRSVLLGGVTVFRERVRHRHSLKARPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SX31</accession>
    <name>A0A423SX31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002634">
        <property type="protein sequence ID" value="ROT68804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SX31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="809" mass="85873" checksum="AFB83E45ECB1EC70" modified="2019-05-08" version="1">MEMQYGDNSIISEICRVIFPALHPITPSSLIKTSHFGPYSNTARLPLRPSQSSTLTSRPRPFPLLLLPPRPRLLPPRPRPFPPSSFYLLGLVPSLPPPFTSSPRPFPPPPLPPRLLLYLLGLVPSLPPPFTSSASSLPSLLLLPPLVPSLPPYLLGLLPPSSFYSLLLLPPRPRPFPPSSFYSLPPPFTSSASSLPSLLLTSSAFPSSSSLPPRPRPFPPSSFYLLASSLPPSSFYLLGLVPSLPPFTSSASSLPPSSFYLLGLVPSLPPPFTSSPRPFLPPPFTSSASSLPSSSFYLLGLVPSLPPPFTSSASPPPRPFPPSSFYLLGLVPSLPPPFTSSASSLPSLLLLPPRPRPFPPSPFTSSASSLPSLLLLPPRPRPFPPSSFYLLGLVPSLPPPFTSSLLASSLPSLLLLPPRPRPFPLLLLPPRPRPFLPPPFTSSASALPSPPFTSSASAFTSSASPFPPSSFTSASSLPSLLLLPPRPRPFPPSSFYLLASSLPSLLLLPPRPSLPSLLLLPPRPRPFPSSSFYLLGLVPSLPPPFTSSASSLPPYLLGLVLGLPSLPPPFTSSASSLPSLSFYLLLVGLVPSLLLLLPPRPRPFPPSSFYLLGLGPSLPPPFTSSASPFPPSSFLPPRPRPFPPPPFTSSASSLPSLSFTSSASLGLALPPLLLPPPRPSLPPPFTSSASSLPPSSFYLLGLVPSLPPPFTSSASSLPSLLLALLLRSSPRLPFSESDGPQHFQSGSVSRFYALALINWNLAVGCQSNPQLIEGQHLPGPITGSRDAKLLFLVRQASFSRFQDAAECCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXZ1</accession>
    <name>A0A423SXZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Opsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012628</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXZ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="8 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT69156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="129" mass="14138" checksum="411661E065C28965" modified="2019-05-08" version="1">MNTKSLRTPANLLVVNLAISDFFMMLTMTPPLLVNAYWGTWILGAFFCEVYAFLGSFFGCVSIWSMVFITADRYNVIVKGVSAEPLTSGGAMMRIAGTWAFTLAWCLPPSSDGTDMCLRVTCLPVVLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZX1</accession>
    <name>A0A423SZX1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_012028</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002522">
        <property type="protein sequence ID" value="ROT69749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZX1"/>
    <dbReference type="STRING" id="6689.A0A423SZX1"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11054">
        <property type="entry name" value="CYP24A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050479">
        <property type="entry name" value="CYP11_CYP27_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279:SF120">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT69749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="49020" checksum="E18115E9C747378A" modified="2019-05-08" version="1">MPPSVYISDPADIEHLFKSTTKEHHKPVFKTLSAIRDNHDFLQPKRAGILTEYGEEWWRVRRRVQPYTAKPKTVAMYLAQMDQVALDFVDRWADLRDENKELPSDFAEELYCWGLESLGLVIFNKRLGYLEGNPEVKDVVQMARDIFHLVQKLELAPIQWWKIKETEDFKQLRQTNDKLLKYVQHSVINACKSLEARSPDSQEELNIVERLLLDDELSFEDVHVYLMDLLTAGIDTTAMTVAFTLVKLAQNPEKQAKLHDELDTVLGDRQELLTPQHMGDLKYTKACVKETLRTNSPAILTMRKLYADTVLGGYIVPKGFTVNVMLNIAGTQDEHFPRAAEYLPERWLRHHPLGPINHYASIPFSTGLRNCVGRRLSEQESYTIVARLLHKYRLEWHYGDLDPIMSIVVTPDKPLKLKMIERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1Z6</accession>
    <name>A0A423T1Z6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mannose-1-phosphate guanyltransferase alpha-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002426">
        <property type="protein sequence ID" value="ROT70433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1Z6"/>
    <dbReference type="STRING" id="6689.A0A423T1Z6"/>
    <dbReference type="OrthoDB" id="285674at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06428">
        <property type="entry name" value="M1P_guanylylT_A_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="3">
        <location>
            <begin position="231"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="367" mass="40449" checksum="CD9C7B7793DC608E" modified="2019-05-08" version="1">MMLKAVILIAGPQKGTRFRPLSLDVPKPLFPVAGLPMVQHHIEALASLPDLREILLLGYFPAQQLQQFVADMMATYKIRIRYLQEYQALGTAGGIYHFRDQISSGNPDAFFVLNGDVCGDFPLQEMLDFHTNLTTPSLITIMGTEATRQQSTMYGCIVEAKDTHQVLHYVEKPSTFVSNLINCGVYICSPDIFKRVGEIFNSRQDFYSDDSEGNESIQLEQDILMPIAGTGQAYVYTTDSVDPSAVLGPNVSVGKNAVIGAGVRIRESIILGNTTIQEHSCVLYTVVGWNSTVGAWSRLEGTPCDPNPNKPFAKMDNVPLFNNEGKLNPSITILGCNVSVPSEVIVLNSIVLPYKDLPRSYKNEIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T290</accession>
    <name>A0A423T290_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002414">
        <property type="protein sequence ID" value="ROT70515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T290"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="30998" checksum="35FD0878A940469F" modified="2019-05-08" version="1">MIAPLIRKVSVLLTNSGREEEAPHSRSGSQEDLKMQQWSLVLLIGSFWGTACTWHHELADPKEGIKEGDVGSVNLKYVLRGDVAYRSPEPGPRPVESQVIGKDVLYDPGRSPRPMAIDFLDKDDVTLTLHIPSQPIGKENSDYHGNGRQNPPQSMLSKKHQISKQIKDQSVLITKLNGLEEETSLKRLLVEILETLKDCGLLVAYDSVYEHSTLLKEILDLPLRRQVVRVSSAEDMDSVLWGKSSCQAYLFLLGDYRTFLAFNHVLDDSWDYEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4L3</accession>
    <name>A0A423T4L3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002311">
        <property type="protein sequence ID" value="ROT71315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4L3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019330781" evidence="2">
        <location>
            <begin position="32"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="496" mass="54365" checksum="755FA42FA893EA27" modified="2019-05-08" version="1">MKTKGSPITRRENPPLLLLWLLASFLSLSSPSPSCWRPFLLSFLSLCWRPSSLLLPLLLSGVPSLCLLCLLPAAYSPSSFLRFLLLLSLLLAFLPLTPSFFSSPSLLLLFSLVLPSLLSSPALLLAISPFVLPSPSLLSCCFFSLTRPSSLLLLLHRPPSTSIFSTDPFLCLSHSWVFIPLLVLPLGSPLSSYLFSSLDLPPSSRFLHLSLVPASPWSLLLLVLLVLLLGSPFFSSFFLHLYLAPPCLALSFFSSFSFSTWHLPPSPRLYFLLLLLVPRIVCLFRFFVFFVSLLRLDLLLFLLLAPSPFLLHSAPPSSTSFFASCLPLFSISLLLNSTSSSSSSFSFEPSSTSSSLSSPSSPIPLPLNFNSFYSFSDTLPPPPSPVLTLSSPSSSFTSSPSSPHLPSPRLLHSFLPRLPPPLPLPRLLTHSFLVFLHSPFLPSSSSSFASPLLVCEEIFSLDICAFEDSPCIFHHYYSVPSFSLSLPLPLSIRPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6U0</accession>
    <name>A0A423T6U0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002190">
        <property type="protein sequence ID" value="ROT72227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6U0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="45362" checksum="4613CBAE71DD71CA" modified="2019-05-08" version="1">MPLIEELASTTSEEPASTTSEEPLRRRFFRGPASTTSEEPASTTSEEPASTTSEEPAKRQSKSRKRKKTEDASTTSEEPAKRQPKSRKRKKTEDASTTSEEPVKRSEKPARQQSEKPSKRQSEKPYVVTYHVLPYMDRLFHPQLFARLETELGVRITVPKGFSGDLLVRGSRQGVDKAMNVIEPLADAARERNRVEEAARQAREDAEARKKAVQAQKPQKPQGPNPKKWPIKEDLDVPKDHHRFVVKAAREITTTCKVRLVVPPKDDASTSITIWARSAKALEDAKMMVEQAMTKQKKQVRWPITETLEVPKALHRFIVTAARAITSTCQVKLVVPPKEDESTSVLVYARSPEMLEAAKVMINEATANKPTTLQRSVFVPRVLHGQVAAKELTGVKYTLPAEGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAN4</accession>
    <name>A0A423TAN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAN4"/>
    <dbReference type="OrthoDB" id="6382360at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="294" mass="33764" checksum="C8008AE45EF0D0BF" modified="2019-05-08" version="1" fragment="single">MNTRQDCENAPTQTTMTDPDQTLARWWYASFDILDRLLVCVEDGVRIPQDQHLQIVKILRTMLRRFRCLLRRDAAKGWLTNQTELIQSLAVHFLKNVILSSRRSEFLAGVEANVSEDAALLDELLGHSNTAVLMSVLRGSSVLWERKEVRRSQLGAFCIIAEFIMTVYLARATPDEDCQWRGLMLARMWLVNCPQDRRKEVKLKVMRVLPHVVPWKRSGKQCGKKRFLTSKLLEVKLIKLVKMAPPYPEAAEAGLDKLFDSQTGERSIRIFLSRLEADILLLRRCLSQVSRATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAW0</accession>
    <name>A0A423TAW0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Metalloendopeptidase</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_007955</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01002014">
        <property type="protein sequence ID" value="ROT73629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAW0"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000015">
        <property type="entry name" value="Meprin A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 10 11" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="12">
        <location>
            <begin position="10"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT73629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="210" mass="23815" checksum="897188C4CAD5ED8C" modified="2019-05-08" version="1">MEGPLPPFKNGLVDEKYRWPDATVIYEIAGDFTADDLTTIQTAMDYFYDRTSGCIKFKERTNEDDYVRITSDDSGCHSSVGRKGGRQSMNLESPNCLKRIGTVEHEMLHTLGFHHEQSRFDRDDYVTIMWENISSGHEHNFATYPEDVATGFGEPYDYGSVLHYSRKSFSANGEDTIVPADPNAEIGQREAPSDIDVAKLMKMYKCGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB43</accession>
    <name>A0A423TB43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Disks large 1 tumor suppressor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002007">
        <property type="protein sequence ID" value="ROT73675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB43"/>
    <dbReference type="STRING" id="6689.A0A423TB43"/>
    <dbReference type="OrthoDB" id="78824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031594">
        <property type="term" value="C:neuromuscular junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098839">
        <property type="term" value="C:postsynaptic density membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045197">
        <property type="term" value="P:establishment or maintenance of epithelial cell apical/basal polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043113">
        <property type="term" value="P:receptor clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097120">
        <property type="term" value="P:receptor localization to synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099072">
        <property type="term" value="P:regulation of postsynaptic membrane neurotransmitter receptor levels"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050614">
        <property type="entry name" value="Synaptic_Scaffolding_LAP-MAGUK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119">
        <property type="entry name" value="DISCS LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23119:SF51">
        <property type="entry name" value="DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="15608" checksum="5FE3B0562FABC9DF" modified="2019-05-08" version="1">MERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPIAIFIKPKSAEQIMEWNKRMTDDQARKTYERALKVEVDFGEYFTAIVTGDTPEEVYARVKDLIHHHAGPKIWVTCKDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDB0</accession>
    <name>A0A423TDB0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Hexosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_007024</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Golgi apparatus membrane</location>
            <topology evidence="1 11">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01001890">
        <property type="protein sequence ID" value="ROT74473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDB0"/>
    <dbReference type="STRING" id="6689.A0A423TDB0"/>
    <dbReference type="OrthoDB" id="5512589at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000001">
        <property type="entry name" value="Hexosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF378">
        <property type="entry name" value="BETA-1,3-GALACTOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT74473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="361" mass="40034" checksum="0460EE905A2BD93E" modified="2019-05-08" version="1">MRHIVTVRLAPNTRLRGPSSPGALSLPSMCDRMPAMISLRTLFVLATLMFLVLIALNPSPPSPSLPFSPHPVPSRAEGPVLNPYPDQVTFLVNEEKTCKDPPLALALVVTAPSNAKKRHFIRNTWGHPALVEVTGIRPLFVVGQTVDPAAQATLSQETSQYHDVIQANFRDSYQNLTYKTTALLTWASTYCSSTPIVLKIDDDVIPNPIALQKWLINFLESHPHPSEIMGKVRCCDPVLRSGKWGVSEERYPGNSYPPYVAGPSYMVPMPVVSALLQAVRRTEFLFLEDVYTTGLAAKKGGISHYNIFTLTNSLPNKIDVFWCSGARVFQENVGLKEATRGWNKIRELEGIIEPPEYVFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDN8</accession>
    <name>A0A423TDN8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PKD/REJ-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001885">
        <property type="protein sequence ID" value="ROT74507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDN8"/>
    <dbReference type="OrthoDB" id="6366166at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002859">
        <property type="entry name" value="PKD/REJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02010">
        <property type="entry name" value="REJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD/REJ-like" evidence="1">
        <location>
            <begin position="39"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="48098" checksum="AF871B17F45E7806" modified="2019-05-08" version="1">MQLRATNCTYRFCAVMYKEFPSVRTEGQWDREPRKAEGCMNVGVVPGSPPLVEIKCQVPKMCRITDRGTIINPNSRVALMGSCADLCWGNLLYSFKIYAVKGGEPERIENDVDYMIGHTKPNMVIVKKLFTDFPDVLEFHIKMGVVRVMDGEVGVGTMFLLINTPPEGGTCTLHPPPNRKDKIAKYSFFLKNNEWGYIKNLKFGIDSKDKFVFPFGNWTFWVTIEDEFGAARDYFIAGFSTSLPSRLEYEAWKEKKEILRASGEGDQARLNQLLQARTSIKGITLEDEPWETTTTTPVPTYAPDDIIETTTMDPEELARIRAEQAAKLAEEQTEAAEEINSMMSQLEMINTDTLSDCTQLFSTVSSIVGDGKTVDIKGKDLATKQVTGTCLTKVLLNMTISDPAEPEAFVSNSMQSISSMTTVRTSKDHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDY7</accession>
    <name>A0A423TDY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001867">
        <property type="protein sequence ID" value="ROT74646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDY7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="46076" checksum="46C5C3BE4EA5BB1C" modified="2019-05-08" version="1" fragment="single">MSYPLFFPFSSPSFLFFSPPSSLSSFSPSLLPLLPSSLSSLSCPSLIDSFVHPFRSSSPCPLSFLLCPSHLSSFSPSSLFFLFTPPVLRSPIVFPCLLFSPLSPSPSSPKPLPCSPFLFSHSSSISFLHLSPSLNHPLLPSSPPSFLFPLSPTPPFFAIFFYITLTSSLSPSFSSTSLPPPPLPNPSPPPPPPRPPPPPPAPLPPAPPPPQRFPHSLPLPSSLISIFSHHSPFPPYPPPFSPSPPSFSSLSSLPLTPPPPFPPPFFLTPLPSPAPLPLLPLSFHHRFPHSTPLPSPLLPIPSFSFPPPFSHPPFFPPSPLLPNPFPHPLPSLPSPPLPPSLPLPSPVLPIVFLPPSPHSLPPFPTIFLTPLTPSPLPNPSPRAILSATNYSSSRFIPDVSWPREMRMLVIPQHPSVTSPPRRTCSSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEK8</accession>
    <name>A0A423TEK8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase</fullName>
            <ecNumber evidence="9">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_006557</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
            <location evidence="9">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001832">
        <property type="protein sequence ID" value="ROT74924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEK8"/>
    <dbReference type="STRING" id="6689.A0A423TEK8"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052723">
        <property type="term" value="F:inositol hexakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="457"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="507"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="666"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="788"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="979"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="539"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="811"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="990"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1033"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT74924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1043" mass="115378" checksum="D7356E531A81AAB8" modified="2019-05-08" version="1" fragment="single">FLEDLKFQEEQLGSITYGHFSGINRKVQLKYQPQGWKRRSSSEEGDSPKEPSLVLILKWGGELTPAGRIQAEELGRIFRCMYPGGQGEYAGTQGLGLLRLHSTYRHVIRSDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDCYKHQHMVKNRLHEAMQQDCDLTQEAMEKLNPTNSRSISTALEFIQNPVRMCEHVDSLIKKLNERIKIRKEDQKTKDLPLYHGETWELMQRRWTKLEKDFRTKNTNFDISKIPDIYDCIKYDLQHNHHTLQFEYAEELYKCAKYLADVVVPQEYGMTQQEKMAIGQGICTPLLKKIRADLQRNIGGEECEGYQGESINRLNPVYSRGVSSPGRHVRTRLYFTSESHIHSLLTVLRFGGLIDGKKDEQWHRAMDYVGAVSELNYLSQIVIMLYEDPTKDPTSDSRFHIELHFSPGVNCCVDKNLPPGPGFRPKSRNEPPLSPKAEEEMRRAKAASCIDEEIDLQSILEEMAEKRETEKSEDGYKDNDDEDDDNNKEMDKDRFTESVGSDQGSLSQTPTSYVPTLGPKVDHQKEIFLTPATSNELEKYEDFPSGSLQPEGLDVPDDDIRLGNKSEPILITNRSHSDCGLVPVELRRPYPILRSLSDSAASCHCSAESLVRPRSVETDNGLNIESTYKTDKGSSSLDSVSDEESLRRHRHSIPGHLSSYLSFLTSLQQKAAAIVAPAVPVFSTAVISGSTSSPDLQDNFTGLSFSSNIEGLGGVPPIRPLETLHNALSLKQLDAFLEHMALAQFRTPLSSPPKMPSTPKQSRSQPPPLGLQSPSSSIGWSGPPSFVSSSGPSSPNLTTLEFFSHVHQCYDTYMPPSSSPSPQLLLPLNLHSTNTANTTATVTAISSELTTHLSSSITKAFSTTNFVALPMPPTSTSDSGEKTSLTDGAVTAATVVDNLADISSFCEKEEALYTSFSESSAGEFFDCEGDMGTASAVLPWEGSCPASPSEGSESLGSHSQTEMGSVIECGDTATPETHSEAQEQESLSSEKFTVEDETLLHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF47</accession>
    <name>A0A423TF47_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT74997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF47"/>
    <dbReference type="OrthoDB" id="6361604at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019464715" evidence="3">
        <location>
            <begin position="31"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="256" mass="28344" checksum="8FC03C0BDA02F5AE" modified="2019-05-08" version="1">MEGVFGRWRGRLVIYGSLVLLLKILPATTGLSDAPSYPDENPQPPPCPPGDPICQKEDVHEDITGGESLGVPGNTNNGQGDGDKDWNKDTDEESMDGRRESPKEEVEVILDCVFSTIPFVGGKWLTKVFRERVSDATLMEATNSFIDGGELLINLINLKPRSVPVKFFKALSSCFEFEEDYNPYAREEGERPTQRKGDSNMDEETQAKIASSTLSHQRKRRSAKGGYGKDTLYGFSLLGLLIVGSLIAYLIYLLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGX2</accession>
    <name>A0A423TGX2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001752">
        <property type="protein sequence ID" value="ROT75617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGX2"/>
    <dbReference type="OrthoDB" id="6356757at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="139" mass="15440" checksum="D168A5240AA51F07" modified="2019-05-08" version="1">MDTDSECTSSGTCMCEAQCKSQDITGHGSCDCGSQYFPVWPTVFGIIGAILIFIFWHHQIAKLCRKYKYNGTLHPHMRDEPPPPPPRENSAEHPRETAWDAPPPYDALTKTGPPPMPSGISIIHTDSKCTTFLSFCQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIS9</accession>
    <name>A0A423TIS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001669">
        <property type="protein sequence ID" value="ROT76355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIS9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018979172" evidence="1">
        <location>
            <begin position="16"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="412" mass="44246" checksum="260C6D4EBD55A09B" modified="2019-05-08" version="1">MIIIISLRLSRLLVCFLFPRPFLLISPSLHLPILPFFSSISLPPPHLFSSPSLPLSSPPFSLVSPSLPLPSFLTPFHLFISSSVSPFSPAPSHSLSLLLLLHSFHLFFSSSAHSLPLSFPPTPPPLFHLFISSPLLQSPCSSPSLLPLPLCPSLLSLLPPSFPPLYLLSPLSNLPYFPLSFPTSLLPLSFPSLLHSPPLYLLSPAPISLTPSLFLPPPSSPLSFPSSSLLPPLLFPLLSLPSYHLFISSPLSPQSPLLPPPLLPPPSLLSPHPPFHLFISSLPLQSPLTPSSLPYLPPPLHLLPPPSPPTHLSTSLSPSPPLQSLLLLPPSPPSCPLFISLSPSPTPLLPPTLLPPLLPLSFPPPIHSLSPLPLTNLPYSLPLSFLSLSLHAHDPRGDTSLENYTQFGVNAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKB5</accession>
    <name>A0A423TKB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001596">
        <property type="protein sequence ID" value="ROT76891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKB5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="356"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="530" mass="59755" checksum="5069B2BE5F8EB249" modified="2019-05-08" version="1">MPSVHSHMRISSAQVQRKRSTPRLISGVHPSSGKLVLAVYVVWGFSNRHPLTSRWRQTFGCRSDGHPLTWRLQSRSLQHRQLFQEDMESKILPKSNVVVSARDRTEDLGRVKRTSSVPSRAEDNTFLKKLRLRLTETAGDAAVTWIAASTSEDDPPSGIRTSGATEMLEDACCFLMNRRLFFLSSSPLFLYFLSTLPNSFSPSLPCPFSFLFFSLFSLPSSSLLYPLSFPLLLSLSSLLTFPPFSSLPYSSSPSLPLLPFLPSPFYFFSSSPFSSIPPPFSTSYLATIPTTWMEMDISDAKNFLIFSLSSFSCSSTRSFFPFKFSLPISPLSFSFPLSFLFIFPTSPSLSLSSQPYCYFLILSSLPFILFSLFSSLLIATSFSSLSSVFLFPPLPSYSLSSPHIFSFSFLLLFAILKTLRLCPPFPFFLPFSSSLPFSLLSSHSFPTFFLSLTSPFLSFNLSFPSLLSFKPSSYLHSASFAPLSSAFYLSFLFYSFQWMRRNRMNFEAIWDNKLQNVGLRFAMQSSLEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLL2</accession>
    <name>A0A423TLL2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_004038</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 18">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001538">
        <property type="protein sequence ID" value="ROT77337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLL2"/>
    <dbReference type="STRING" id="6689.A0A423TLL2"/>
    <dbReference type="OrthoDB" id="431497at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03272">
        <property type="entry name" value="ABC_SMC3_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1060.20:FF:000002">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1620:FF:000002">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000370">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000424">
        <property type="entry name" value="Structural maintenance of chromosomes 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041741">
        <property type="entry name" value="SMC3_ABC_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0469">Meiosis</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="20">
        <location>
            <begin position="531"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="179"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="399"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="676"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="866"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00034085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT77337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1200" mass="140514" checksum="33A2200AAA6F6E2A" modified="2019-05-08" version="1">MYIRQIIIQGFKSYREQTVIDPFDPRHNVVVGRNGSGKSNFFYAIQFVLSDEFSHLRAEQRQALLHEGTGPRVISAFVEIIFDNQDGRIPIDKNEVCLRRVIGAKKDQYFLNRKAVTKLDVMNLLESAGFSRSNPYYIVKQGKINQMATAPDSHRLKLLREVAGTRVYDERREESKEILRETESKREKIEEFLRTIEDRLKTLEEEKEELKEYQKYDKMRRALEYTIHDRELKETRKKLDDMENQRKNSGAEQEKLRQQLQKAQDAIKTSSKEMKDIKQKLGQVKEERDTFNMEQQQLLKEKTKLEFTIKDLADEVQGDNKSKERAEKELQKLRSTISQKEAELEAIRPQYEEMKAREDEAQRELSLKDQKRKELYAKQGRGSQFTSKEQRDQWIQKELRSLNKAVKSKQDQIQRLEDEISRDSERRVQLDKKVEELSADTEDYRQSIDEHNKVFYEMKKRKDQLQSERNEHWRKENNLQQNVSTLKEELSSRDQSLRSMAGKPILNGRDSVQKVLDTFRERGGHLGEIATQYYGLLIENFECERSIYTAVEVTAGNKLFHHIVESDKIGTQILKEMNKQKLPGEVTFMPLNRLTVKDIDYPQTNDAIPMVSKLTYSDRYLKALKYIFGRTLICRNLEVATHLARSTRLDCVTLDGDQVSSKGSLTGGYFNTSRSRLEIQKARSELRDQITSAETELRTLQETLRNTEQEINKIVSEMQKTEIKNSKAKNLFEKVKTDIRLMKEELSGLERTKQPKERSLSQLKANLEAMMATKEGLESELHQDLMATLSVQDQREVDQLNDDIRRLTQENKEAFTRRMKLEADKNKLENLLTNNLHRRKDELVQALQEISVEDRKRQLEHSQSEIQRVDSRIEEVAVQFKEVEKKVVEHQKKEKSLKAELEKLKLKEKEVMERMEEDAKDLEKMASKQNLLHQKIDECTKKIRDLGSLPSDAFDKYQNLATKQLFKKLETANTELKKYSHVNKKALDQFISFSEQKEKLVSRKEELDRGYDKIKELMSVLEHRKYEAIQFTFKQVSKYFSEVFKKLAPQGHAQLVMKSDQDEESEQEEQGTVDNFTGVGIRVSFTGRNAEMREMNQLSGGQKSLVALALIFAIQKCDPAPFYLFDEIDQALDAQHRKAVADMIHELSKDAQFITTTFRPELLEHANKFYGVKFRNKVSHVECVSREEAYDFVEDDQTHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMB5</accession>
    <name>A0A423TMB5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Histone-lysine N-methyltransferase trithorax</fullName>
            <ecNumber evidence="2">2.1.1.355</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_003740</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.355" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001506">
        <property type="protein sequence ID" value="ROT77599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TMB5"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035097">
        <property type="term" value="C:histone methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042800">
        <property type="term" value="F:histone H3K4 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140949">
        <property type="term" value="F:histone H3K9 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15664">
        <property type="entry name" value="ePHD_KMT2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15508">
        <property type="entry name" value="PHD3_KMT2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19170">
        <property type="entry name" value="SET_KMT2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000004">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000002">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047219">
        <property type="entry name" value="KMT2A_2B_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45838:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE TRITHORAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45838">
        <property type="entry name" value="HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00542">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00541">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="14" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="20">
        <location>
            <begin position="635"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="18">
        <location>
            <begin position="2347"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="19">
        <location>
            <begin position="2469"/>
            <end position="2485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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    <feature type="region of interest" description="Disordered" evidence="17">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <begin position="1212"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
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            <end position="1475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1982"/>
            <end position="2013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2035"/>
            <end position="2071"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
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    <feature type="compositionally biased region" description="Low complexity" evidence="17">
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            <begin position="1389"/>
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="2055"/>
            <end position="2069"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00071661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT77599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2485" mass="274319" checksum="E3401550C4FF194A" modified="2019-05-08" version="1">MMECGRCGEWIHAHCEGLNNERYQILSFLPDTVEYVCRSCVTESTSTWLHAVSSELMAGCEAVLQALIASRCAKHLVKREASSKVSSSGGLTPLPCLPEVGTSIQARIDDALVERVEGLDSLLPATNTNTVAVESHSTTTSAESNTGEVSPLSGSNVCVSITTVAAGDSYVSSTLEGTSSSSDTSHIVGSVDDLGVGAPQTSSKSDDCAVDTNKNFSASLCSVIVNRTDIPQEGAGESSKLSGDQTACFSDNQSENVAANKSTGKSGCITVAKDKSDLKGKSSKEKNADESKAISRRQTRSSSGGVALLGSAGSIGNAADPIKLKECSVRLEDICKARSPSSSPIKTQQSEMENVPVVEDKKTEETSKSQETIVEDTLIKDSDERTTESLESLEEKELERETRDTLQGILALKDTDVSCTQVDGPNDETTATARVIRNLFFEDRSQMMLDTTSLLESKTKVDEKNLAHVEAQLISPKDKITKDIDDDCVSSEESSYCDTDTEIESIQDDPEEPRDLLSVKEKLRERKYDSVLQFHVDMVRVIENGRHLNRSQTRNVQVTYTKHMKECFPWFDIKTANVFELVDKQRPFPLPHWDHSYVYRPMLSGTRIFSVRDVPLYRKRSTSPLKGAQASPPDRRKCVLCGREGDDEPNAAGRLLYLGQDEWMHVNCGLWSSEVYEEVDGGLQNIYLAVSRGRLIKCSACNERGATVGCCHKSCQATYHFLCARKACCQFMEDKRIFCPLHESTSNGEEKTDDFKVSRCVYVDMDSEKKKWKQVAGNRVSIIIGSLTIKNVGRIVPESDSAEALIPLDFLCSRVYWSTVDPSKKVTYTCRTKRVVPAFDDSTLVGDAAFHRTIDHSLGEEAVSKEMAAVRKWFKQLEERKVEKKSRETNIIPPHLCPLYRSIREREQETRVVEKIVRCRTPPAIVELDVRQCIDDIIDRVSRSVEEESLLLDTDLPAIVSADDNELISMVLNDLDACDSITLQSTPSTSGRPSPLDIDFLSTCDHMMDSGKVSHSGNLTQEAQETECDPQGIMDAASLSPRLHPTLAAGIDPIHETYRVESPNADVKEPIIETIAPPSMQDLGSVPSSSTKSLQNTCNSSQNIRRSSSASEHSDAIGHAGHNHSPPAANQSPRNSDENEGNSTAGRGSERKKICMKRNYKTVIKKYPLRSGMRKSKPYETVQIEINETIEIPGGEGSGMVRKSLKRKWSGILDSEEEEDNNQKETGIDQEGQEETTNRSSDGENSKENSVSKKVLKFSDDNNDITVSIVNNNNLCEFSKSRVHKYRHKTVLQLDGAADGSSSSAEMSESQDEGTGEERRRLQEQEDPQTPPLHSALAMRIKEQSLARSSPGEEGPYKCGKCKRLYRTKESYQKHIETCTFEVDSSSTSEDEEYEEVHIEEEEEGTSSTLPHLQEEKIDDVIQENLHMPSLSEREEYPSISQHNVHVPLLSEDSVMPNTSANQPSDIDVSAQSVDDTKPSVVVDLEGHARPSGEEPAVKRARLDVTLPRLHGVHRQVRTAIKKCQSTSEDVELLQVVRGPPPPGSDVFVPPPVSPVKFSPVVKKSASPRRYTNVRLLRGSRGYQYRRAAPHLPGPHEHYQGTNSGVQMTPSAAPAPIQVAMHPMTNNSGQNLAQGALAAFQQFPGQSSQYAGTPQLTSPVTHLTSAVQVTPQVTSQVAPQVSPQVSPQVLTMVSAPSVAVPQGYTLQYVGSFRDGEVAAGGGGLVTYPAAPVVVPQPQLVMTPQQSSVVVPQVVNTNITYTFTAPETLVINQPAMVPGMQSVQYLPQQQQQQQQQPQVIHHPEQQVGAVMQYNQTGVSPQQVPVSHMHTGQVHTPCMPYSDIQASPICMQPHAQTAIVTRELSFTGGGSKPLQSAPCIGSSQNRSSHGVAVSLPVTSTCSGPIARHRPQASVAPQVIQPQPTLTTSSSDVNLIESQGHSRLPFSDRPLTGVVRTVATVAPAIITTTTMVSLSTCSSATRLTSMDTSPKVATVRPRPTYSYRDAMREKQLERQKQRQEVLQLDRMNISDTHHDFLKEREGLDVNISDSETDSETETTSHDAEKEKEDHLETQSYKLVLRKDSSASTGFNVLPISGPTTPLPSPEVKELRIKAKVSVGPKRKKAKSRDPEKDLIIVNKDTSSDLYVNEQLPNFSVNPMHNPADDPAMFDKPKACSAEPYIVFELTSEDGFRVESRHIAEVWQKVFDAVAAARASMRMDPKVPHNIQQPSSPGDSISGLHMLGLTHNAVQYLLEQLPGAKDCHKYSFQFHRRPQEEGAVEENPTGCARTEPFKTRSPYDIFSWLASKHRRMPERSLVQQEEIQLSTTRRATSLELPMAMRYRHLRETAREAVGVFRSSIHGRGLFCKRDIDAGEMVIEYAGQVIRSSLCDMREKDYESKGIGCYMFRIDDDTVIDATMHGNAARFINHSCDPNCYSRVVDILGKKHIIIFALRRILRGEELTYDYKFPIEEDKIPCTCGTRRCRKYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRC1</accession>
    <name>A0A423TRC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-specific adenosine deaminase 1</fullName>
            <ecNumber evidence="8">3.5.4.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">tRNA-specific adenosine-37 deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_002285</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically deaminates adenosine-37 to inosine in tRNA-Ala.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA(Ala) + H2O + H(+) = inosine(37) in tRNA(Ala) + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50968"/>
            <dbReference type="Rhea" id="RHEA-COMP:12855"/>
            <dbReference type="Rhea" id="RHEA-COMP:12856"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.34"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>1D-myo-inositol hexakisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ADAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.34" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01001305">
        <property type="protein sequence ID" value="ROT79006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRC1"/>
    <dbReference type="STRING" id="6689.A0A423TRC1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043829">
        <property type="term" value="F:tRNA-specific adenosine-37 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090266">
        <property type="term" value="P:regulation of mitotic cell cycle spindle assembly checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46516">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46516:SF1">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A to I editase" evidence="13">
        <location>
            <begin position="96"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT79006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="16379" checksum="BDF87890AB192791" modified="2019-05-08" version="1">MAQPPLFPTLTPRLVDPAWFQVDKPVDLAQELKDQEQVYQEQMLAIQQKGSDIVPIGKSATEQTGAKTVGGEQEDPRLPGADYHVTGALRTKPGRGDPTLSMSCSDKIFKWTVLGVQGALLMLFLKSPVYFETITIETVLPVCPQILAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSV1</accession>
    <name>A0A423TSV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001775</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001233">
        <property type="protein sequence ID" value="ROT79511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSV1"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF296">
        <property type="entry name" value="MEIOTIC P26, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="21"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="8">
        <location>
            <begin position="95"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="405"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="566" mass="62279" checksum="EFEB4CC65F1B6621" modified="2019-05-08" version="1">MNGRPPCSSDVCPGEAEDLMCAVCSEAFEAGTREPVVLPQCGHTFCRPCLQNLKAMTQTLKCPACRKKHKGLPVAKLPANFTVLNLATSHKHRKSSSEVCLKHGDHIGLWCRLCNIPLCGQCLFENHMTHGYQVIKMQDVIREKKNKIAEQTTTILRHIDKEREALTREVHEIAHQLAKLYKKSTDLNNHAKDANKILKNVRKTTRIKSILANQNSLENLFAEMNITFGDEKGDRTSKDLDSNSMVVARRRSHIDRVIGWQEVPIQDNRDSNKNDLEPLDIECKKSVTSSASNQTFDNSVNEILSATKTEPDLDAEKGNQLSRKVRKDGKDSVTSDSDSVEQDGDDGLESETSSETKVKGRDLPKWSLKCAPGGSSVWPCIDWQDFYKQLPAVQLLVPLDRPEVIMTLSVGAKSLGRVHIRLWGHLRRAQHFLALCLGTFGASYKGSRFTNVARKGLAGESLVGGRYLTARGSSSAGLLSDLEWRGKFSGPVTEGVLGGASDGDTSSEALFGICTKGYPEGEYYCPFGEVVSGLEVVRAAVAHSPVTEVTIADVVLVSSEAKKPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT97</accession>
    <name>A0A423TT97_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_001591</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001203">
        <property type="protein sequence ID" value="ROT79685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT97"/>
    <dbReference type="STRING" id="6689.A0A423TT97"/>
    <dbReference type="OrthoDB" id="10259843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17947">
        <property type="entry name" value="DEADc_DDX27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="254"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="458"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="649"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="621"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="721"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="784"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT79685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="793" mass="89679" checksum="F848D60AF970F69D" modified="2019-05-08" version="1">MVKQSGRDNKIKMHPPVVNSNGQCELRPPAFVSNDDEDEDPNEFPGVVDLNTVYANMSNSEFGPGTINSDEEYDGDSDEDNLKIADVEGGTDFFAGFKTNYKYSDTWDTIISYLKPKTTVDVKNTVAKVVQREKEEKKIRKQAKKDNDIKGEDSSSDSDLDLGDDDEYDLDIDKLKLKDSEAKRMERLKTSQKKEKKTPEEIEKEIEEAKYFETAIPCEAGSTTFLEMNFSRQIMKAIEGMGYQSPTPIQATTIPIALQGRDICGCAATGTGKTAAYMLPILERLLFKPKEDLATRVLVLLPTRELGIQVFEVTKEMSKFTSITVALCVGGLDVQIQEHALRQIPDIVIATPGRLIDHLLNAPNFHMKKIEILVLDEADRMLEENFEEQMREIIKQCATTRQTMLFSATMTSQVRELAIMSLKDPVKVFINNNTDVAQNLRQEFVHIHKGQSNLRDAVLVYLVLRCFKSNTIIFTPTKVLAHHIHILLTTFGVDSGELHGDLKQTDRVLTLKNFKDGKIDALVATDVAARGLDIAGVQTVINYTVPAIYSRYVHRVGRTARAGRCGRSVSIVGDKEFKMLKDIRKLSKTPLYERVLDKKILSKVHAKLIKMKPVIQKVLQEEEVDKQLRKVENTIDAIEKRLENPERERVWMDSKDGKPMSKNKKRRLKQKEMLLKKRKGGEDEPSGPLSKKQKKQQKKKELERMVGGKAGKGKMKMKSLRCRDQDEEGKFRAPAARDRGAARFTKGNPQDGDKSSFSRELTSVSRKSLKKFRGTGASMQGVYRSHKSKKPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TX09</accession>
    <name>A0A423TX09_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001043">
        <property type="protein sequence ID" value="ROT80967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TX09"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="713" mass="77416" checksum="B3E012916FF1492E" modified="2019-05-08" version="1">MESLGVCTSTHLPPTQPPHHTTLLYPPSYRPPTALHTPLPTSHPLNPHPPPYHLQPQFPTHRTSQPTHITHLLPNPTLLTPLYPTSHPLIHLYPPPIHSPPSNHLPPLTPLYPSLHPTNPPSTTCPPTHPPLPSPHPLTSPLPHLHPLTPLYPPPTPTHPPLSHLTTHLTHSFATSHHTIPPLPTSHPLIPLYPPPTPLLTSLRHSHPPLPTSLHPTVTPPRAPPTHSHPPLPILPPHSPPLYPPPHPLNTAPSNPSAPPKLTPPSTILPLHLRPASTTHLPPYSPSTHSHHSPPRLYPPATHSQAPHLAHLPLTHNLLYPISHRSIPFPLYPTIPPLNTPLPNLPTHSTPLAPPPPHQPPSSPSPTHSHPLLPISHLITPPLPTLPRTHRTSSTTTSPPHGTPPLTISQPTQPPLYPPSHPLHLLYPHLPPTQPRLYPSPTHLPPLSTASPTLYSPHLPHLPRTPPPSTTPNPPAPPTHSHPLYPSAHRTHPPSPTLPPHSLPSTTPTHSLSLYPRSHPLTSLLHHLPLPQPPLYPPPTPHTPSTPSHPLTPPLPTSPPTHIRLYPPPTHSPPLPRSHPTHTLLYPPPPTHTPPPPLTPLYSPPRHSHPLYPHSHPLTPPPTHSRPPSYPTSHPLTTPSRPPTTHPPTHPLTPPSTTLPAPHPPLPPLPTSSPPPNPTHHPSTPPTHPPHPPPTHSHTPTHPPYSTPPPTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXM0</accession>
    <name>A0A423TXM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polycomb protein SCMH1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000025</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001002">
        <property type="protein sequence ID" value="ROT81199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXM0"/>
    <dbReference type="STRING" id="6689.A0A423TXM0"/>
    <dbReference type="OrthoDB" id="5912862at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09578">
        <property type="entry name" value="SAM_Scm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.190">
        <property type="entry name" value="SLED domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050548">
        <property type="entry name" value="PcG_chromatin_remod_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047531">
        <property type="entry name" value="SAM_Scm-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021987">
        <property type="entry name" value="SLED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038348">
        <property type="entry name" value="SLED_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247:SF132">
        <property type="entry name" value="POLYCOMB PROTEIN SCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12140">
        <property type="entry name" value="SLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SAM" evidence="8">
        <location>
            <begin position="215"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT81199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="288" mass="31353" checksum="87D0E7E62258A476" modified="2019-05-08" version="1">MVAGPESTIPVPQQKSPSITVTEPDTSTVHKLSASVVVYVNHGCTCGPYLDSGRVSELPVQFGPGSLNRVVRESVQALVDAAPDPRAVTSLLPRGNGKVIIKDGDAETHRLTSLEKVEDFWSALESLFEDLMCCENFYTQQPITQCTKCARQSPAQFKRDQEAAQHVAVSNNKRPASSEPSDVLSPSKVAKRVLQEPSPSSASEPGQSPRPRGDPAEWTVEEVITHIAATDPALANHADLFRRHEIDGKALLLLNSDMMMKYMGLKLGPALKICNLINKIRGRKHLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXQ7</accession>
    <name>A0A423TXQ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein 188</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_000008</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNEP1R1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001000">
        <property type="protein sequence ID" value="ROT81243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXQ7"/>
    <dbReference type="STRING" id="6689.A0A423TXQ7"/>
    <dbReference type="OrthoDB" id="5786980at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071595">
        <property type="term" value="C:Nem1-Spo7 phosphatase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019168">
        <property type="entry name" value="NEP1-R1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20996">
        <property type="entry name" value="NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20996:SF1">
        <property type="entry name" value="NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09771">
        <property type="entry name" value="Tmemb_18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT81243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="126" mass="14222" checksum="3D07C901BB962E04" modified="2019-05-08" version="1">MSLEQTACEDLKAFERRLTEVIARLQPATTRWRMVLVIMAASTALGAYLWLTDPITQEVTFVQSLLNHLFFTFAAITLILLFMMGIHKKVVSPSIITSRTRTVLSDFNMSCDDTGKLILKPRPTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U331</accession>
    <name>A0A423U331_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">High-affinity choline transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023729</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000739">
        <property type="protein sequence ID" value="ROT83094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U331"/>
    <dbReference type="OrthoDB" id="546820at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005307">
        <property type="term" value="F:choline:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008292">
        <property type="term" value="P:acetylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11474">
        <property type="entry name" value="SLC5sbd_CHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1730.10:FF:000008">
        <property type="entry name" value="High affinity choline transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052244">
        <property type="entry name" value="Choline_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45897">
        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45897:SF4">
        <property type="entry name" value="HIGH-AFFINITY CHOLINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0530">Neurotransmitter biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="627" mass="68560" checksum="0F8807CE61C7A72C" modified="2019-05-08" version="1">MQLKEETRGRGLARCRRVSPKASPSWHRQLCSERQGVNKRHGPSPQRFLLSADSFTGKSAPFVSTAKDATMLNIPGLAGIIVFYLAILGIGVYAAWKRRDKGANSDEVMLAGRSLGSFVGVLTMTATWVGGGYINGAAEKVFDMGLIWCQAPFGYAISLSLGGAFFASHMRKAGYVTMLDPLQNAFGRRMGGLLYFPALMGETFWSAAILSALGSTLSVILDIGNTVSIIVSAAIAVAYTLFGGLYSVAYTDVVQLFCIFMGLWLTVPFAMTNEAVGSLALNETNWLGSIEATSPEWGLWIDYWLLLICGGIPWQVYFQRVLSAKSPKQAKILSYAASFGCILSAVPACLIGAIAKATDWSLTDFERTPKDYEKKLVLPLVMQHLTPSWVAFLGLGAVSAAVMSSADSSVLSASSMFARNIYKNVFRQQATEREVIWVMRIAIVVVAISASTIGILINSIYYLFKLCGDLVYVILFPQLLLVVHFREYVNTYGSFVGFCMGFLVRLLGGEPYIGVPAVIHYPFYDEERGQQNFPFRTVAMLVSLTSLIVISAIAKLLFTKGIIPERYDFCHCFTDAPSDKGEDKQELSQDDTLHVASLKKEQSSLQAAEGKLYMPSASVEDGHVNKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5U1</accession>
    <name>A0A423U5U1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Insulin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_022752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000599">
        <property type="protein sequence ID" value="ROT84059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5U1"/>
    <dbReference type="SMR" id="A0A423U5U1"/>
    <dbReference type="STRING" id="6689.A0A423U5U1"/>
    <dbReference type="OrthoDB" id="8193245at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00064">
        <property type="entry name" value="FU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000494">
        <property type="entry name" value="Rcpt_L-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF611">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01030">
        <property type="entry name" value="Recep_L_domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="545"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="616"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="13"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="648"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT84059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="670" mass="74660" checksum="BF955DE9EAD707D8" modified="2019-05-08" version="1">MSWSTLARKFGRSDSISSLSDTSCLSPHPYQIPPHNVSSPNTSETPIDTLPSPDTEPNVNPSSEPLENPIPGHLVNPSPTSLSPGNATTDPAVTDYVLIYRVSHLSTLDTILPRLAVIRGNVLFHEHALVVFGNIHLRELGLSNLTAILKGSVRIEKNWSLCPGTSDRWKGVTSDQVTNIVQDNYEMCIYDPCEGTGNCTLYTSAIYTNCLNVGGCREGEQCHPECVGGCRLPGNATACVACKHYQHGSACVRTCPAQSPRNVHDLRYKCVTASTCEAMSGIVRMMELPESDISAPVCIHCDGNCSRTCKGETITSRNTGRNLRGCRKVNGSLNISVAGGLNITQQLEENLGEIEEVSGYIRVYGSDTLFSLNFLKNLRHIRGEEKMHGLYALYVLENANLQELWDWRQRSDVLHIHSGSLFFHYNPSLCPLLIQKLVVMTSVKNQKYANISNESNGNSLPCFESELPVQAQAGEDVGTIIVRWQHEYHGIDDRFVIGYYVFYRETNENVTLFGGRDACNDNEIWRRDFWEYNRKQNRSVEGSSWFWTVLVAFLCGGMLGICIMELTVWFRRRRRSAGPDTPQYVTHNPNYGELLLGDTLQQIKEKYVISRNTLEIDLNNKLGEGCFGLVYEGALSMASGTELKVAVKALSEQSAYSEVKRFLQEAVIMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5W2</accession>
    <name>A0A423U5W2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit beta</fullName>
            <ecNumber evidence="11">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_022728</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01000596">
        <property type="protein sequence ID" value="ROT84088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5W2"/>
    <dbReference type="STRING" id="6689.A0A423U5W2"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000026">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="229"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT84088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="520" mass="55489" checksum="18D158B2B4AA5D1F" modified="2019-05-08" version="1">MEYWEVKPRRAEQTRTGLSRALVSLPSQSPPPGIMLGAAQRACSTILKAAKPAVVSKGLQNVGSKTLPALYTCQRNYAAKAEAATQTGVANGSVVAVIGAVVDVQFDGELPPILNALEVANRSPRLVLEVAQHLGENTVRTIAMDGTEGLIRGNAVVDTGSPISIPVGPGTLGRIINVIGEPIDERGPIPTEHFSAIHAEAPDFVEMSVEQEILVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVISLKDDTSKVSLVYGQMNEPPGARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGSMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVVQKILQDHKSLQDIIAILGMDELSEEDKLTVARARKIQKFLSQPFQVAEVFTGYSGKFVSLPDTIRSFKEILAGKYDDLPEAAFYMQGSIEDVIEKAEQLAAQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7C1</accession>
    <name>A0A423U7C1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lipid scramblase CLPTM1L</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cisplatin resistance-related protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Cleft lip and palate transmembrane protein 1-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_022219</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a lipid glycoconjugate involved in post-translational modification of proteins. Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>6-(alpha-D-glucosaminyl)-(1-octadecanoyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho)-1D-myo-inositol(in) = 6-(alpha-D-glucosaminyl)-(1-octadecanoyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho)-1D-myo-inositol(out)</text>
            <dbReference type="Rhea" id="RHEA:71495"/>
            <dbReference type="ChEBI" id="CHEBI:190691"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)</text>
            <dbReference type="Rhea" id="RHEA:38691"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phosphocholine(out)</text>
            <dbReference type="Rhea" id="RHEA:38571"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol(in) = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol(out)</text>
            <dbReference type="Rhea" id="RHEA:71491"/>
            <dbReference type="ChEBI" id="CHEBI:57997"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000522">
        <property type="protein sequence ID" value="ROT84586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7C1"/>
    <dbReference type="STRING" id="6689.A0A423U7C1"/>
    <dbReference type="OrthoDB" id="378564at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00036810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00093208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT84586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="257" mass="29156" checksum="716CF969100C1BA4" modified="2019-05-08" version="1">MALGYTLPSLTTVICGVFTAYIIHSAWTLGQLFMPPSCPEYSECLHPLIAQEPKFQLLAFTSQKKMPEYATDLRLVHRDWGSVVKDDLTVYAMAHLTKYHIPEAATINLLGREEEKKQKPQSGRKRPVTHFQSLVVFNILTDPVSLPRNAVPYDIGRSLRLDSNGQYLPILYVDSLSARLRDLVEVDFSMKETNLTLKYSPISYGKIRLWMQFEAALHPMAHLGFTDKDLDEVKGIFSDTNLYFLCVTFLVAALHVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U820</accession>
    <name>A0A423U820_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000486">
        <property type="protein sequence ID" value="ROT84848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U820"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="53256" checksum="B22AD0EDB658756F" modified="2019-05-08" version="1">MTITYQGNSNGAPYTPSGFAPSTPHPPPPLAPLSLTLFPSSSFSVFLVYGCAPTPPPPSPLPPPPSPSLLPNPLPTSSSSPSPSPSIPPSLLLLGAMAVLHQPPPTLPFFPHPPPLPPSSPPPPSSPPPPPPPPSPSIPPIPSFSRPSSVSIPPPNPSPPPAPPLLPPHALLPPFLPSSHPPPPTHPHPSAATVIAPPDNTSEINPSPSPGSFALTPRSAVPRMIIRRGAASQAPFPPLTLTLTPTTASLLPLSLITPYIPPLTVYLNSDPLPLPYLPTPSPLYPPPAPFPSKIPPLDTLESSRHLSPSPHLPAHPRALFPSTPSDASPLFSSPHTKRLLSSPLSAPPSLSATVFSPLPFIPLPPSCSSTSTSSSIRLIHFMSLSPYPPPYPPPFHLPQFHPPPPLLSLPLPLHLPTSLHPFLSLHLPFHPLPPLSPLHPSPPLPPSSSPPFPSFPPHPTLPPPPPPPHTSPPSPQPTQKSPPPGRFLQSSLWEGATRPPHQHSEPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBM3</accession>
    <name>A0A423UBM3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_010237</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion inner membrane</location>
            <topology evidence="1 14">Peripheral membrane protein</topology>
            <orientation evidence="1 14">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000023">
        <property type="protein sequence ID" value="ROT86065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBM3"/>
    <dbReference type="STRING" id="6689.A0A423UBM3"/>
    <dbReference type="OrthoDB" id="274922at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.810:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038:SF16">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="15">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT86065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="96" mass="10984" checksum="E3DCA9E7B67B4B84" modified="2019-05-08" version="1">MAGLPALNDDQMKLVQDLEIEMMSDMYTRMTNSCHKKCIPTKYKDSEIAKGEAVCIDRCVAKYWEIHERVGKKLQNMSTQDEEALKKMAAQQGLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTU9</accession>
    <name>A0A3R7LTU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Teneurin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_019437</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tenascin family. Teneurin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003560">
        <property type="protein sequence ID" value="ROT62722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTU9"/>
    <dbReference type="STRING" id="6689.A0A3R7LTU9"/>
    <dbReference type="OrthoDB" id="442731at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008045">
        <property type="term" value="P:motor neuron axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008038">
        <property type="term" value="P:neuron recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000001">
        <property type="entry name" value="Tenascin C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000021">
        <property type="entry name" value="Teneurin transmembrane protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000013">
        <property type="entry name" value="Teneurin transmembrane protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051216">
        <property type="entry name" value="Teneurin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057629">
        <property type="entry name" value="Teneurin1-4_GBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219">
        <property type="entry name" value="TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11219:SF72">
        <property type="entry name" value="TENEURIN-M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25024">
        <property type="entry name" value="EGF_TEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23093">
        <property type="entry name" value="GBD_Tenm3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 12" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="274"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="14">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT62722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="559" mass="61707" checksum="45A7F99C90D6EF7D" modified="2019-04-10" version="1">MAPHIRGIPKEFRQNFATSRLQPVPRSRSRGPDDIFDQLIIEKGTNLGLYARKGKLPTHTQHDIMKILRGNRQRDIRASPVSTPVRVSCDCSRLGDGYVWLPGIDWARFFLRAVFLGRALRVQAPAVIRLGAALNIPKVCYEDYPPIKPALPPVPTRRRRPIRGRPNSRRQSNMAGGRDVSEVLVLPCARPFVLFRLFFLLRCKTLPNDVLSRDSGSESLAFSGSLFAPTSSHTESMVELTVEEVLEAGEWFLSIYNDDGDPHQVNLVITRGPGGGECPQRCHERGNCILGRCQCAPGYSGIDCSQVLCPILCSGHGAYVGGQCICHPGFKGKECQLRHHECEVPDCHGQGHCVDGRCKCAKGYTGEFCQTVDCPNPKCSGHGWCVMGTCVCQKGWRGDDCSEMDVDAQQCLPDCSGHGAFSIEAHACVCDHLWTGSDCSKTPVAFPSLRLTSLPLLAARRPIFRASNFDFVRVSRRVLDHSVCFGGLVACAGDAGMRGDNRPRRRFSELLFMPFEKHSGFSASPFSSPFFFFPFSPPSSLLSPNSFLRSPALFFPLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUI8</accession>
    <name>A0A3R7LUI8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Speckle-type POZ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_017365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Tdpoz family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003209">
        <property type="protein sequence ID" value="ROT64691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUI8"/>
    <dbReference type="STRING" id="6689.A0A3R7LUI8"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18345">
        <property type="entry name" value="BTB_POZ_roadkill-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.210.10:FF:000028">
        <property type="entry name" value="Speckle-type POZ protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000008">
        <property type="entry name" value="Speckle-type POZ protein-like a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24413">
        <property type="entry name" value="SPECKLE-TYPE POZ PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="64"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="BTB" evidence="7">
        <location>
            <begin position="238"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="434"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT64691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="55721" checksum="605E78CC9D496E0D" modified="2019-04-10" version="1">MIARGNLVRDRVAVGHAHSVHGGGGHVSSGGVSMSVSRVPSPLPPENNMPVAENWCYTQVKVIKFSYMWTINNFSFCREEMGEVLKSSTFSAGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSSNKSEVRAKFKFSILNAKREETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLYCEIQCAQVSVVADSVNISGQSNAIHFKVPDCRLSDDLGILFESQRFSDVTLSVAGREFQAHKAILAARSPVFAAMFAHEMEERKHNRVEIQDVDHEVLREMLRFIYTGKATNLEKMADDLLAAADKYALERLKVMCEEALCTNLSIENAADVLILADLHSADQLKAQAIEFINTHATDVMETQASLSLARPSPPTPLASPPGHPLTLGLTQWVLLPYYSGQRRESDMERSMEDWRASIGHPIVESDQGHKKPVCGSGTWQGIGTRPLIPPVNRVQSGDDKSLPTQVGRAAVPSSTAPNSFCPVTSPPNDLSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZN3</accession>
    <name>A0A3R7LZN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Akirin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_018807</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the akirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003452">
        <property type="protein sequence ID" value="ROT63299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZN3"/>
    <dbReference type="STRING" id="6689.A0A3R7LZN3"/>
    <dbReference type="OrthoDB" id="10039914at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045089">
        <property type="term" value="P:positive regulation of innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024132">
        <property type="entry name" value="Akirin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13293">
        <property type="entry name" value="AKIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13293:SF6">
        <property type="entry name" value="AKIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT63299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="104" mass="12078" checksum="42BD9302DB3AA50D" modified="2019-04-10" version="1">MLQSGERSMECEGGYDTGLGSLHHHQHPHHPHHSSLGKDKPLFTFRQVNLICEQLLREREVKIREEYDKVLASKLAEQYDCFVRFTTDQIQQRLSQAALPSYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0K7</accession>
    <name>A0A3R7M0K7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C1q domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018040</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003337">
        <property type="protein sequence ID" value="ROT64033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0K7"/>
    <dbReference type="OrthoDB" id="6154955at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001073">
        <property type="entry name" value="C1q_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050822">
        <property type="entry name" value="Cerebellin_Synaptic_Org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008983">
        <property type="entry name" value="Tumour_necrosis_fac-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22923:SF116">
        <property type="entry name" value="C1Q DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22923">
        <property type="entry name" value="CEREBELLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00386">
        <property type="entry name" value="C1q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00007">
        <property type="entry name" value="COMPLEMNTC1Q"/>
    </dbReference>
    <dbReference type="SMART" id="SM00110">
        <property type="entry name" value="C1Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49842">
        <property type="entry name" value="TNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50871">
        <property type="entry name" value="C1Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018700232" description="C1q domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="C1q" evidence="5">
        <location>
            <begin position="45"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="19038" checksum="15FB09893A7A63FB" modified="2019-04-10" version="1">MVRLGLVIALLATACGLAWGQVNPGAQIIAAALPPETLAAPPAPAPTCSSGFSVRKAARGTSAATGASRTRLRFQEVLTSEGGWSPSESDFQAPCRGLYYFSFHGVAQDRGDFTLALMKDGQYQVTAYGGKGSFQQGSNSALLLLNPGELVHLELQQGSLYEHPFDEAYTSFSGFLVKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6R9</accession>
    <name>A0A3R7M6R9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">small monomeric GTPase</fullName>
            <ecNumber evidence="1">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_008054</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002023">
        <property type="protein sequence ID" value="ROT73516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6R9"/>
    <dbReference type="STRING" id="6689.A0A3R7M6R9"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008544">
        <property type="term" value="P:epidermis development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032486">
        <property type="term" value="P:Rap protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04175">
        <property type="entry name" value="Rap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000182">
        <property type="entry name" value="ras-related protein Rap-1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038851">
        <property type="entry name" value="Rap1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT73516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="20891" checksum="F6D561AF70CCD1A5" modified="2019-04-10" version="1">MREYKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKDQGLNLAKSFSCAFLESSAKAKINVNEIFYDLVRQINRKSPDRKLNGKGGNKKKCCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7F9</accession>
    <name>A0A3R7M7F9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT75003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7F9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="42883" checksum="C03CDBE859FEE47B" modified="2019-04-10" version="1">MAPRRAPHEPHGPQERWPQHPWPPGEQPHGPPPHGPEAAPAPRRAPQPQESTPWPPAPHGPRRAPHGPQESTPWPRRAPSGEHPMAPRRAPHGPQESTHGPRRSTPWPPGEHPMAPPGEHPMAPRRAPMAPPRRAPHGPGEHPMPPGEHPMAPRRAPHEPPWPPGEHPMAPGEAHGPRGEHPMAPRRAPHWPPGEHPMAPRRAPQAEHPIMEESTHGPQESTPWPHGPQESTPWPPTQPQERAPHGPQESTPWPPGEQHPWPPGEHPPQHPWPPGEHPMAPKERHPMAPGEHPMAPRRAPMAPRRATHGPQESTPWPPGEHPMAPRRAPHGPQESTPWPPGEHPMAPGEHPMTPWPQRAPHGPQESTHGPRRAPHGPRRAWPQVGSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9W9</accession>
    <name>A0A3R7M9W9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010638</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002348">
        <property type="protein sequence ID" value="ROT71053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9W9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018774645" evidence="2">
        <location>
            <begin position="16"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="793"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="327"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="658"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="905" mass="83435" checksum="62C87B490FB7B209" modified="2019-04-10" version="1">MKTFIILLVAALAAAQRFQQRVPDVAVKLASAGFFQQGGSFSSSSGSNFQRNSGFQNSGFGSNSQSSLSSGNIASSSFFTPAGNGVGSSGRFQSGSGFGSGFSSSSSAGNGQLQSGLAGSSGFGSGSSSGRFSSGSSGTGFGTSSLSGNRLGSSSFGSGSQFSSAGSSGSNGFGFGSSRGSGAQFGSSLGSGIQSGSQTSSGNSGNFQSSTFGSNTVKLAGPGTFSTGGSTIGSGSSLSSGFGSGSSSSSSSGSGFGSGSSLSSGFGSGSSLNSGFGSGSSSGQFQSGSSSGSGFGSGFSLSSGFGSGSSSSQFQSGSSSGSGFGSGSSFSSGAGSGSFNSGSGSSLSSGFGSDSSTGQFQSGSSGSGFGSSISSGFGSGSSFSSGSGSGSFNSGFGSGSSFSSRSGSGSFNSGFGSGSTGQFQSGSSADFGSGSSFSSGSGSSLSSGFGPGSSTGQFQLSSSSGLGSGSSLSSGVSSGSSSGQFQSDSSGFGSSSGGQFQSGSLGSSGSGFGSSSGSSSGFGSSSSLSGGFQPGSSGAGVSSISSLSSGSQSGSTFGSSSGSGISSTSSFDTGFQPSSLSGSGFGSSSGSQSGFSSGSGSGFQSGSSSGSGIGSTSSLSSGSQPSSLSGSGFGSGSGSQSGFSSGSGSGFQSGSGIGSTSSLSSGSQPSSLSGSPFGSGSGFQSGFSSGSGSGFQSGSYLVLQLAPLLPLPADPAQFSIWFCIRFRFWISVGFSSASGSGFQSGSSSGSGIGSTSLGSGFQSTSLSSSPFGSGSGSQSGFSSGSGFGSSSSLGSGFQSSTPSGSGFGSSSGSQSGFSSGSGFGSGSSFGSGFQSGSSGAGFGSGSSIDGAFQSGSSGSGFGSSSSGFGSGSSFLSGSQTGSSFGSGFQVDPLPADGVFEPLNLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAG8</accession>
    <name>A0A3R7MAG8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucuronosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_010293</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAG8"/>
    <dbReference type="OrthoDB" id="6345490at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000050">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT71417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35764" checksum="AFE18825B5FDE99C" modified="2019-04-10" version="1">MNTNERAKATALLPCAREHRVNIRHCPPDPPPHPYLVYRCVDLAKWVDEAGEAGFIFFSLGSAVKPSDLPETYRKVLVNVFASLRQRVLWKWDEEGMADLPPNVRLGKWLPQQDILGHPRLRLFITHGGLLSTLESTYHGAPVLGVPVFGDQVGNMVEVQRQGWGRALRWGDFGEEVLRGTIHSIMDNPEMQAVVARRSALMRDLPVTPAREVSYWVSYVVRHGGARHLRSPLFALPCCLSRISQGYQLISSNTLVAAVTYLRQMRLERTWFVREEAGKQSAEGFLKQPAGKNLLFPGVLVPEERKRASENKQGELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDJ3</accession>
    <name>A0A3R7MDJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin/ribosomal S30 fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_002311</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001308">
        <property type="protein sequence ID" value="ROT78971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDJ3"/>
    <dbReference type="STRING" id="6689.A0A3R7MDJ3"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT78971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="14813" checksum="58FE3F3BA26C2ECA" modified="2019-04-10" version="1">MRFYVRSRTTHVVEKAEEHTVGDVRACVCQAEGLPLEKVRLYAAGSLLEDDSFPLVELGVDSIEVNVGLKGGKVHGSLSRAGKVKGQTPVVEKKEKKKAKSGRAKRREQYERRVLHGSGASSGNQRGPNAQGESRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEL8</accession>
    <name>A0A3R7MEL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001908">
        <property type="protein sequence ID" value="ROT74355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEL8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="481" mass="52770" checksum="39ED4CB3C7F698D3" modified="2019-04-10" version="1">MRSCLSHRAHRGGGGVPRGRKALRAKWPCWRAKWPSRRTKWPSRRAKVPSLRAKWPNPRRSGQGGQRCLAEAKVAKPQNEVAKPQNEVAKPRTKETVDAEMRNGVRISPRTLQHFLRQPVAAADKPNYPGLAWLRWGLRLDRSRARSPAPFPAPFLVLLSLLSGFSGLTRRALRGAARPSFLLGRRLVFRRDTFPIPLTSLCSRPLLVLQVFAGIAIVAAIIFIIALSYPLPSSSPAPSFLLLFPRFPSSYVFSRPFPPPPPLPSLPSASPALRSPYSSSPLLFFLFLLSPSPFVFSCPFPPPTPPLPSLSPLPSSSSACSLLLLFPLFPSSFAPPTPPPASPSLLDGAGIVLLILLLSVTTQEFWLLFPLCRETGRRGGVRGGGMSELGHPAPQQGGRLSNSTMRAPSFPRINGPELFLRNFSFAGLHFVALPMTSELPGSATVLRAGLRPAPAPCPLGSCERCLPRRLGRRWKDRLIRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEN8</accession>
    <name>A0A3R7MEN8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zinc finger CCCH-type with G patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_000751</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transcription repressor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEN8"/>
    <dbReference type="STRING" id="6689.A0A3R7MEN8"/>
    <dbReference type="OrthoDB" id="5842926at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20384">
        <property type="entry name" value="Tudor_ZGPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297">
        <property type="entry name" value="ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297:SF1">
        <property type="entry name" value="ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="16">
        <location>
            <begin position="313"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT80515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="516" mass="58188" checksum="4897B63E52252C99" modified="2019-04-10" version="1">MATEELLASIEIYQNQLKEIEGALSSAEEAEKQQLQELQANLLQLLDLTLQQLNQQSQLKGEEEPQQHTSGSRNSDDSSQSASDKSSSSCSDKNLDDEFALFQSEIADIAGTADEEEKADSKYSKAELLAVEGTHCRAPFVEKWGGHTYHNAVVLSFVQVLFSQPTCREMLTCRFFLSGRCKYSDDKCRFSHGMKVPFCDIKEYREPDLSGLDSGSRVLVQHTDDLWTNATVQDILEDRSAFCVKLDHSKAVAEVKPNQIIPLHHEEDDTEKYEADSPSEEDSSDDERTVFVPTTNWLQNSFSQRLGEWEKHTNGIASKLMAKMGYVIGTGLGPTGEGRVEPVSAYVYPQGVSLDRCMELREASNGEEMLQVEKRLDRQRRIEEAKSVQAAERLRARTSVFDIINKKLGSKGQETDDSEAVPKQRLNVCKTVLQKDTNKDLNRKNYQLSENIRQLQREITKLEGSRDRQSGNKTAADIISTKILAKKAELQRAQDAERKVQGEQQSRRDAKKFSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MG65</accession>
    <name>A0A3R7MG65_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001758">
        <property type="protein sequence ID" value="ROT75561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MG65"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="12103" checksum="478D0E5480C6A2F7" modified="2019-04-10" version="1">MSRDGQEVEASVGDQLIKLWDKSGGSSTGGSGGYKGPNNYMVGSGGPPIMHDPQGPPPPPRHPLHPPHLGPVHSPFHHHFGRNYGNGYGYGGGSGSGGGGGCSGGGGYRGGYRYGYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGG0</accession>
    <name>A0A3R7MGG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Molt-inhibiting hormone 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001035">
        <property type="protein sequence ID" value="ROT81028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGG0"/>
    <dbReference type="SMR" id="A0A3R7MGG0"/>
    <dbReference type="OrthoDB" id="6331348at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2010.10">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018251">
        <property type="entry name" value="Crust_neurhormone_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031098">
        <property type="entry name" value="Crust_neurohorm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035957">
        <property type="entry name" value="Crust_neurohorm_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001166">
        <property type="entry name" value="Hyperglycemic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001262">
        <property type="entry name" value="Hyperglycemic2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981:SF2">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01147">
        <property type="entry name" value="Crust_neurohorm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00549">
        <property type="entry name" value="HYPRGLYCEMC2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00550">
        <property type="entry name" value="HYPRGLYCEMIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81778">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01250">
        <property type="entry name" value="CHH_MIH_GIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018716831" evidence="8">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR631098-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT81028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="105" mass="11995" checksum="46F50EDBC32FB564" modified="2019-04-10" version="1">MYRPVIRIWLALVIAVVGASIFFDSASASFIDGSCRGVMGNREIYKKVVRVCEDCTNIFRLPGLDVMCRDRCFHNEWFLLCLNAANREDEIENFKVWISILSAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHW7</accession>
    <name>A0A3R7MHW7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_020012</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003800">
        <property type="protein sequence ID" value="ROT62153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHW7"/>
    <dbReference type="STRING" id="6689.A0A3R7MHW7"/>
    <dbReference type="OrthoDB" id="37721at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.80:FF:000002">
        <property type="entry name" value="NADH dehydrogenase iron-sulfur protein 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="10">
        <location>
            <begin position="103"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT62153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="278" mass="31804" checksum="E49CA1D41B883E29" modified="2019-04-10" version="1">MTISSPGKKNHRLSHRDQLASVNMASTVIRGLSSLAKNASKSVLPRVAGARFCSTEQTLHPTIRPVNAVERTTLTEYGQYIAECMPKYVQKVQITAGNELEVLIAPEGVIPVLTFLKDHTNGQYTCLTDLCGVDMPSRAFRFEVCVYNLLSVRFNSRIRVKTYTDELTPVDSACEVYAGANWYEREVWDMYGVFFANHPDLRRILTDYGFEGHPFRKDFPLSGYVEVRYDDEAKRVVVEPLELAQEFRKFDLNAPWEQFPKFRDHVPAEDIPIKEEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKM6</accession>
    <name>A0A3R7MKM6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001268">
        <property type="protein sequence ID" value="ROT79249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKM6"/>
    <dbReference type="OrthoDB" id="6372162at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="295" mass="32267" checksum="816C4ECD97E1A4D6" modified="2019-04-10" version="1">MSVRAEAPGGDRPPAAPAAPQPAPIIVDAQLVPGPRPCLPITKQFTQYETVDNYVPIYSTSVSPIYFPTTIYDTKYVTLTNYVTKLLQTTVYAVHTEYETSVSQGLIYESVTLPLSNPEYETRTNIQLAVVPSLVTEIVAVTRPSSQVIPVVKTQTRTLVLVPEYTTTEVVPYPIVTTNTIVETVRVPITTTVTVTAAPLPVPKKPVGPKVTKTLVQTNVHYTPAYVTNTEYVTRYTTVTERQSAGTTSGGEVRRRSCDAVPIFLPFASGCSIRPAERRSGNARWSNTRNAHSHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKN3</accession>
    <name>A0A3R7MKN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000301">
        <property type="protein sequence ID" value="ROT85345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKN3"/>
    <dbReference type="OrthoDB" id="546450at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="212" mass="23135" checksum="5EA9F36410E21789" modified="2019-04-10" version="1" fragment="single">TKSLTSVDDVPTTCWHSGSSTLGVCKKIQECYPYFRLPDLSPEDSWLYGLSDSCPIKTDEGVVFGVCCEGAGASLASPPGDARQELPAQKAPKEASVVKYMVAEGAEGGPGLMDRSHVQFVPPHARPIAASRRPAVGQARYPTYPTHPPFITHEPSHTNKPWWTTRPTGSTPAPPTTTSPWWPPQTTARTTTTNPWDQWTTTTTANPWDHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLD3</accession>
    <name>A0A3R7MLD3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_022034</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01000501">
        <property type="protein sequence ID" value="ROT84772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLD3"/>
    <dbReference type="STRING" id="6689.A0A3R7MLD3"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000018">
        <property type="entry name" value="Mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000013">
        <property type="entry name" value="mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="8">
        <location>
            <begin position="47"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="9">
        <location>
            <begin position="294"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="44277" checksum="23F5CE903B6165BB" modified="2019-04-10" version="1">MAVDDKRRLTGVGGGRAGDGRGGGVGGLLSFSRPLSPPADLTLGNMKALILVGGFGTRLRPLTLSRPKPLVEFANKPIVLHQIEALVAAGVTQVVLAVSYHAEQMEQELAQEAQKLGIEITFSLEEEPLGTAGPIKLAQSILASNDEPFFVLNSDVICDFPFAQMVQFHKQHGREGTIMVTKVEEPSKYGVVIYDDSGKIDRFVEKPQEFVSNKINAGMYIFNPSVLKRIECRPMSIEKEVFPYMAEEGQLYAQELQGFWMDIGQPKDFLTGMCLYLNSCKINNSAKLCKAPGIVGNVLVDPSAKIGKNCRIGPNVTIGPDVVIEDGACIKRCTILRGATIKSHTWLENCIIGWKCIVGKWVRMENVSVCWRGCVIVKDELYVNGGMVLPHKSIAASVLEPKIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MN75</accession>
    <name>A0A3R7MN75_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">INO80 complex subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_025344</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000965">
        <property type="protein sequence ID" value="ROT81501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MN75"/>
    <dbReference type="STRING" id="6689.A0A3R7MN75"/>
    <dbReference type="OrthoDB" id="49520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029525">
        <property type="entry name" value="INO80C/Ies6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31200:SF1">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="5">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT81501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="124" mass="14186" checksum="B47BAF7E263B1D30" modified="2019-04-10" version="1">MVTTEDIIEEKEEKKAPVFKNPEFQHTAFRSSKKRGWKNLKQIIALERGYTWPHDAVHYSSIDAPPAFTPAKKYSDVSGLPANYTDPLTKLRYADSSEFYRVRDLPMDIVNGLLELRKANSIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNP1</accession>
    <name>A0A3R7MNP1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL15</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L27a</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015694</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002962">
        <property type="protein sequence ID" value="ROT66292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNP1"/>
    <dbReference type="STRING" id="6689.A0A3R7MNP1"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="8">
        <location>
            <begin position="72"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="147" mass="16417" checksum="C00E371CA00DC650" modified="2019-04-10" version="1">MATTKKKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGMHHHRINFDKYHPGYFGKVGMRNFHAKPNTKYAPIINLDKLWSLVSEQTREKYAKESKKAPVINVLKSGYFKVLGKGDLPKQPVIVKAKFFSRKAENKIKAVGGACVLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MP26</accession>
    <name>A0A3R7MP26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Jagunal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the jagunal family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000859">
        <property type="protein sequence ID" value="ROT82215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MP26"/>
    <dbReference type="OrthoDB" id="8914197at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009787">
        <property type="entry name" value="Jagunal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20955">
        <property type="entry name" value="PROTEIN JAGUNAL HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20955:SF1">
        <property type="entry name" value="PROTEIN JAGUNAL HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07086">
        <property type="entry name" value="Jagunal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="18974" checksum="2B75666D0DF33760" modified="2019-04-10" version="1">MGSGKAGHGLPPAPAARMGPLCHADVRGWGGHRMEVIVLNKGRLRKCVFSHLLLALLMVVKMVPDFLDRLDIFVLEIEELEVPQIYFGLINLFSTVPILLAAMIYFSEFLKYCTEEEPAGLQLWQGYPVAVLWYSFIMIAMQVHIFTLIFAWKLILAWKNRGAAKKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2019-12-11" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MTK5</accession>
    <name>A0A3R7MTK5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glutamine-rich protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000231">
        <property type="protein sequence ID" value="ROT85611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2636" mass="290190" checksum="F9CBAA631CB4461B" modified="2019-04-10" version="1">MGLITSASGHWDLLLRHPDTGHWDLLPRHPDTGAYYLGIRTLRGLLPRHPDNGAYYLGIWTLRGLLPRHPNTLGLIASASEHFGAYYLGIRTLGLITSASEHWGLLPRHPDTGAYYLGIRTLVLITSASGHWGLLPRHPDTGLITSHPDTSGLITSASEHWDLLPRRPDTGTYYLGIRTMGLITSASGHWDLLPRHPDTSGLITLSSGHWDLLPRHPNTGTYYLGIRTLGLLPRHPDTGTYYLGVRTLGLITSASEHWGLLPRHPDTSGLITSASGHFGAYYFVARTLGLITSASEHWAYYLGIRTLGLITSASGHVGAYYLGIRTLRGLLLRRPDTRTYYLDIRTLGLITSASGQWGLLPRHPDNGAYYLGIRTLRGLLPRHPNTGTYYLGVRTLGLITSASEHWGLLPRHPDTGAYYLGIRTLGLLPRHPDTGTYYLGIRTMGLITSASGHWDLLLRHPDTGAYYLGIRTLGLIISASGHFVAYYLGIRTLGLITSASGHWDLLPRHPNNGAYYLGIRTLGLITSASGHFGAYYFVVRTLGLITSASEHWDLLPRHPNTGLITSASGHWDLLPRRPNTGAYYLGIRTLGLITSASEQWDLLPRHQDTGTYYFGIRTLVLITSASEHWGLLLRHPDTGAYYLGIRTLRGLLPRHPDTSGLITSASGHWDLLPRHPNTGAYYLGIRTLGLITSASEHWGLLPRHPDTSLLITSASEHWGLLPRHPDTGTYYLGIRTLGFITSASGHFGAYYLGIRTMGLITSASGHFGAYYLGIQTLWGLLPQHPNTSELITSASGHFGAYYLGIRTMGLITSASEHWSLLPRHPDNGAYYLGIRTLGLITSASENWSLLPRHPDNGAYYIGIRTLGLLPRHPDNGAYYIGIRTLGLITSASGHFGAYYLGIRTLGLINLGDTGTYYFGIRTLGLITSASEHWGLLSRHPDTSGLITSASEHWDLLPRRPDTGTYYLGIRTMGLITSASGHWDLLPRHPDTSGLITLSSGHWDLLPRHPNTGTYYLGIRTLALLPRHPDTGTYYPRHPNTGLITSASGHWDLLPRHPNKWIITSASGHWDLLLGIRTLGLLPRHRTLGSYYLGIRTLGLITSASEYFGAYYLGIRTLRDLLPRHPDTGAYYLGIRTLGLITRHQDTGLITSASGHWGLLPRHPDTSGLITSASGQWGLLPRHLDTSAYYLGIQTLGLIASAFEHFGAYYLGIRTIGLITSASEHFGAYYLGIRTLRDLLPRKDTGTYYLGIEHWGLLPRHQDTGTYYVGIRTLGLITSASEHWGLLPRHPDTSLLITSASEHWGLLPRHPDTGAYYLCIRTLGLIISASGHFVAYYLGIRTMGLITSASEHWSLLPRHPDNGAYYLGIRTLGLITSASGHFGAYYLGIRTMGLITSSSRPFGAYYLGIQTLWGLLPRHPNTSSLLPGIRTLGLTSHPDNGAYYLGIRTWSLLPRHPDNGAYYLGIRTMGLLPRHPNTGAYYLGIRTMGLITSASGQWGLLPRHPNTGAYYLGIRTLGLLPRHPNTGLITSASGQWGLLPRHPDTGAYYLGIRTLRGLLPRHPDNGAYYLGIWTLRGLLPRHPNTLGLIASASEHFGAYYLGIRTLGLITSASEHWGLLPRHPDTGAYYLASEHWCLLPRHPDTGAYYLGIRTLGLITSASGHFGAYYLGIRTMGLLPRHPDTSGLITSASGHWGLLPRHPDTPRLITSASGHFGAYYLGIRTLGLITSASGHFGAYYLGIRTIRGLLPRHPDTGVYYLGIRTLRGLLPRHPDTGAYYLGIRTLRGLLPRHPNTGAYYLGIRTLRGLLPRHPDNGAYYLGIRTLGLITSASEHWAYYLGIRTLVLITSASEHWGLITRHPDTGAYYLCIRTLGLNTSASGHFGAYHLGIRTLGLNTSASEHFGAYYLGIRTMGLITSASVHFGAYYLGIRTLGFITSASGHSRAYYLCIRTLRGLLPRHPNTGAYYLGIRTLRGLLPRHPDTSGLITSASDTSGLITSASGHFGAYYLGIRTLGYITSASGHFGAYITSASGHFGAYYLGIRTLRGLLPRHPDTSGLITAASDTGLITSASGHWGLLPRHPNTGAYYLGIRTLVLITSASEHWGLIPRHPDTGAYYLGIRTLGLNTSASGHFGAYHLDIRTLGLNTSASEHLGLIPWHPNTGAYYLGIRTLGLITSASGHWGLLPRHPNTGAYYLGIRTLVLITSASEHWCLLPRHPNTGAYYLGIRTLVLITSTSEHWCLLPRHPNTGAYYLGIRTLVLITSASEHWCLIPRHPDTGAYYLGIRTLGLITSASEHWGLLPRHPDTGAYYLGIRTLGLITSAFEHWVLLSRHPNTGAYYLGIRTLGLITSASGHWCLLPRYPNTGSYYLGIRTLGLIISASEHWCLLPRNPNTELITSASEHWDLLPRHSNTGSYYLGIRTLELITSASEHWCLLPRHPNTGAYYLGIRTLGLITSAFEHWSLLPRHPNTGAYYLGIRTLVLITSASEHWSLLPRHSNTGAYYLGIRTLELITSASEHWSLLPRHPNTGAYYLSIRTLELITSAFEHWGLLPRHPDTGSYYFGIRTLGLITPASEHWCLSPRHPNTGAYYLGIRTLELITSASEHWCLLPRHPNTGAYYLGIRTLGFITSASGHWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MY12</accession>
    <name>A0A3R7MY12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002158">
        <property type="protein sequence ID" value="ROT72417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MY12"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="42868" checksum="7A9F424E74B6E341" modified="2019-04-10" version="1">MNYEHTGGQMLSGAAGHEGHARDVAGEGEGRGRVHGEGHWQPPWAASRPKELDWLSGFECGLGAVGMRPSGAARAALCLSVCLSFSLSSSLPSLHPSLSPPPPSSSSSPLSPFPLLPSFFPSPLHSACLSFPNFLAILPFSPSLPLPFLSFFLYPFLSSLSLSSLLLFPPSLPSPLPSSPFLSSLLPPFLSLSPSSPSPLFSLPLLSSCPPLSSFLPLPSPSLSSPLPLASRLLSSPFPPSSPILSLLPFPSFPPPFLSPLPSPSLPPPFPLPSLSLLLSSLPHSSLSLSLSSPFSSPSFLPLLSASLPPLSLSLSPPPFLSLPLPSLPPPFPLLSLPLPFLPSSRFSPLLSPSPSSPSLLPPSSPLSSPFLSLSSSPVPLLSRSPFSPSLPPPSLSLSPSPFLSSPSLSLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NFP6</accession>
    <name>A0A3R7NFP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative multiple epidermal growth factor-like domains protein 6 isoform X6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_003530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000148">
        <property type="protein sequence ID" value="ROT85945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NFP6"/>
    <dbReference type="STRING" id="6689.A0A3R7NFP6"/>
    <dbReference type="OrthoDB" id="409374at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005044">
        <property type="term" value="F:scavenger receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007157">
        <property type="term" value="P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000002">
        <property type="entry name" value="Multiple epidermal growth factor-like domains 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.300.10:FF:000041">
        <property type="entry name" value="Tyrosine protein kinase receptor tie-1, putative"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.300.10">
        <property type="entry name" value="Tie2 ligand-binding domain superfamily"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042635">
        <property type="entry name" value="MEGF10/SREC1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043:SF8">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24043">
        <property type="entry name" value="SCAVENGER RECEPTOR CLASS F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00053">
        <property type="entry name" value="EGF_laminin"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12661">
        <property type="entry name" value="hEGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00011">
        <property type="entry name" value="EGFLAMININ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SMART" id="SM00180">
        <property type="entry name" value="EGF_Lam"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50027">
        <property type="entry name" value="EGF_LAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="316"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="402"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="464"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="502"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="550"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="593"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="716"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="760"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="802"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="882"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin EGF-like" evidence="8">
        <location>
            <begin position="890"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="972"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="484"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="779"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="822"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1026" mass="107998" checksum="194036181A4F916F" modified="2019-04-10" version="1">MKIGEDVSTSRDGEQDRDLVTVIEHDTNITNTVIHGCPRGFFGPGCQSSCDQCPGKCSEGGCVCPPGRTGPNCQEPCPAGSFGQDCKQVCECENGGSCDAETGSAYVLQESWGIGVRMAVPQASLDKPADAAVPSNARTRVAIGSSGSCQCRVQSTRLCRPEDGKCECQPGYTGRNCSDLCPPGRWGADCENTCVCEDGRRCDHVTGACLQECPAGFTGPGCERPCGEGSFGPGCKRVCECGVRPCDPVTGECRCAPGFHGENCLLPCPEGLWGVDCLQKCECEGNSTCSRVTGACQCPRGSTGEACERQCRPGRWGEGCRQSCRCLNGATCDPVTGKCICGAGFTGPYCGRHCPPGRHGHDCAHVCQCPGGGQCHRVTGHCSCPPGRTGQKCRETCPEGSYGVDCAMSCRCENNATCDPVSGACTCTPGWQGRYCSEPCPAGFWGRECRRVSCPPDRWGPTCENICLCHNGGTCDRVSGLCMCPPGFTGATCQDRCPPGSFGEKCQFSCLCQNGATCMHDTGACVCPPGYRGTYCEEGCDDGSYGPGCLLTCACQRGGKCDPVTGTCTCPPGWDGEKCDRPCPQGLWGQDCNNMCNCKHGGSCHHVTGVCQCPSGFTGENCEDICPRGFYGKDCNQRCTCARNQPCHHITGACKCPPERGHSAMIESGASSARGVPVQGSSLCDPSAAPACVPQALEAGSVAKVVLQAFMASSARRWKCECENGGRCNSTTGACECPEGFYGPTCSLPCPDGTYSTHCNQTCDCEHGGVCTRSGECRCPAGYVGPKCENRCPADKWGLQCANECQCKNDAICHPATGECQCGLGWTGDDCTLPCPTGHYGPTASWTALPPQRTCDRFSGCCICGPGRYGRYCELECPPGFHGDYCTQVCECENDATCNPYSGQCICPPGLTGDTCADRCPEGTFGLECQKECQCGPHPCRKDTGECLCPAGFKGPGCEMQCGPGRYGLGCQQQCECRNGATCDPATGQCTCPPGWIGPTCQEKDLSVFTTHPDHRDRSDIPVEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NMJ0</accession>
    <name>A0A3R7NMJ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative Krueppel-related zinc finger protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_020131</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003859">
        <property type="protein sequence ID" value="ROT62044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NMJ0"/>
    <dbReference type="STRING" id="6689.A0A3R7NMJ0"/>
    <dbReference type="OrthoDB" id="6361754at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000710">
        <property type="entry name" value="Zinc finger protein 768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF66">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT62044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="475" mass="52713" checksum="121EB92C113C00CA" modified="2019-04-10" version="1">MGLHPGMWAQPQQYPMVAMPLPPRRAATPPQLQAEDDTPEPPAKRQRVGASFDWAPDFDTSLFEQEKHEPKARVVAPPLLTPPPLPPEQEQPEDLSGAQEDDPLAVSPPPASYLEAAPELEAKAQSTPYLPKLEPISPPEPSEHRPDSPEGGGEPPTPVLQYTNPLHQHHQHQHESHAPSRIMPESVHLEQLGTVTISSPYPVMSHHPASHAEALQVIPGESQHPSRPHAALHHSSPHHHESPFSGDHQRLQTIHEQQVIPITYVPATPDGGQGVAGGEGGHPSFRPSYAGEGLPAPSRRRVVRTMSNYKYTREKNAECYICHKKYESKYKLKLHMYSHTGERPFVCEVCGIGFTRGPNLNAHRRVHSGAKPFPCTRCGRGFRHPSDRIVHMVTEVCTRVSRHVQATASGGWMCGACGEENFESEEQAERHARQHETGRAMACPVCLQNFKGCKAHRLVRHVREHHPEYITSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NSY1</accession>
    <name>A0A3R7NSY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">I-connectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016129</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003018">
        <property type="protein sequence ID" value="ROT65894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7NSY1"/>
    <dbReference type="OrthoDB" id="6612025at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000425">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000080">
        <property type="entry name" value="Myosin light chain kinase, smooth muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000119">
        <property type="entry name" value="Sallimus, isoform P"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000430">
        <property type="entry name" value="Sallimus, isoform P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000962">
        <property type="entry name" value="titin isoform X1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF4">
        <property type="entry name" value="MYOPALLADIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="21"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="194"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="317"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="416"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="564"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="697"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="836"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="970"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1103"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1237"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1371"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1505"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1637"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1770"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="1902"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="2034"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="2167"/>
            <end position="2257"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="2302"/>
            <end position="2393"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="2435"/>
            <end position="2521"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="2568"/>
            <end position="2654"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="2700"/>
            <end position="2790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2811" mass="314710" checksum="1A21827F6979E016" modified="2019-04-10" version="1">MMPVGLPAGASPPVFEQIFRNARFAQGGDAMFEGKVQGNPKPTVTWTRKGAQIVSGNKYQVTHDENTGVVTLNITAIGPGDEGEYTCTAANQYGEAICTVYIQPEAAYMMQQQRQSMQMQQSKSMMQQQQMSQTFSQQQQQMMSVQNGHMESFRVDTFEYRLLHEVEFRRSLTITVAGELEVDLGAIQGPPQAPQLQQKPRSTKVSDGGNATFTVNVNGYPTPRVIWFKNGVGLQQSDKYLMTQSAGHPGEAGELTGQRLLHNAGRELLWLAVVPRGEVTNGAPSPEVIRPERIEQQQAQQQMEVDVGEESGKSLEPKFVRGPADREVQEGKMVRFDARCSGRPYPEVTWYINGQLVVDDATHKVLVNEAGNHSLMISKASLSDAGVITCVAKNKSGEANFQCQLNVLEMQQMVAPKFVERFQQGAVAEGETVVLQCRAVGTPMPFLTWQKDGVSVENNPNVMVQSDQNGASTLQILSASGSDAGWYQCNAQNSAGSAATRARLHVQTTKPSGPAQPQRPHFPRPVKFIEPEPEPEPEVIMLRPVERAHHVPKAPEEEQPVEPPKFTHPLRDIDIVEGTRAHFEAKVTPVGDATMNVEWLIDGKPLAASSRATVTYRFGFVALDILNVIKADAGVYTCRATNAKGQAETSANLRITERPLIESQTQHPEALQQISYLEDQSRYQRTVSIEESSTIKPSFVKPLANLGEVMEGKYAHFEAQLHPVSDPFMRIEWFKDGKPITASSRINVIYNFGYVALNIMHLRPEDSGTYTVRATNKAGECQCQASIQVITLSSVTGDLGIPEQAQHIRSVEEMEAYRLQMQQRTAQEIAEATTAPVFKTELKDATAREGGYAHFEARLEPIGDPNLKVEWLKDGRPIEASSRITSFFNFGYVALTVKALIIKDAGTYTCVAKNSKGEAQVTAQLTVLSKTDTEVETQYQETVAKMQYLEDSTRYQKTETEETSAVTIPPKFLGPLKGTNKIVEGQKAHFEIRLEPQSDPTMTVEWYFNGQVIMSASRIKTYHDFGYVSLDISDVRQSDAGQYTVLARNALGQAQMSSVMTVETRSAIDTTSMHEVTLSKTSAMERRHQEPQYDIEEISRSKPEFTQLLSDPKPLPEGKNVHLEARLEPMNDPTMKVEWFFNGKPITIGSRFKTYFDFGFVALDIIGAYTTDSGEYTCRAENMLGSAHTSSCVRVIGTGDVLSESMHDNAMEQIHYLEDASRHQRSMQEQTEINEAPTFVKSLKNIETIEGTNIHLEARLKPVGDSSMRIDWFFNDEPLKVGHRFRPAYDFDYVALDLLSVYPIDSGIYTCRATNKLGQAVTSASVKVTAKKDLVFDSEHPDSLQKLQYLDDSSRYQRRETMEEVSVKIKPRFLTQLKSVTLKEGMNAHFEAKIEPITDPNLRIDWYRNGMPIQLGSRFRLIHDFGYVALDISRVIEEDSGTYTCVATNLMGKDEITADLKVLNSASIVMESQNQTMTMEQLQMLEDRSKYSRTEQVEETTKQAPVFTSSLKNIEILEGQRAHFELKLIPTSDPTMKVEWFHNNVPVKSGSRFTEYNDFGFVALDIMYCYAEDSGTYTCVATNCMGQAMSTGNLVCHTKETILSDTMNQEAMSKISRLESSRTQRTITTEEITMQAPVFTAPLRDQQLIENAPLHFEARLIPVGDPDLKVEWFKNNVPIQQANRISTMHDFGYVALDMKYVNPEDSGTYTCRATNRLGQAVTTASLVVTSKEALLLDTQHSEALEKLRYLEDSSRYTKSTTEETVITQAPKFVVKLSGLTKLWEGQSAHVECRLEPYPDPSMKVEWFHNGQALQVGHRFRTMYDFGFCAMDILQAVAEDSGTYEVRATNRIGTATSSITIEVKPKSDFIVETQHPEAMAKITRLEQKAPHRLPEDAVVIEKPNFGRPLRNQDHLIEGQSIHMEATLTPVNDPTMKVEWFFNGQPIPQGHRFRTTYDFGFVALDILYAYPEDCGTYMCKATNAAGQAVTSCSIKVEGTGSMQLGTVDEERMRKIRQLEAMGHKAEEIKDQVFQKPVFTTPLNSVDNLVEGERCHLECRLEPINDPDLKVEWFVNGVEIKAGHRFRTTHDFGYVALDILYSYAEDSGTYLCKATNKMGEAVNSCNVTVSARRSIYLDTQHPMGWEKIQSLEHRGRYERIEVSDVPMQPPRFTSELRANNTLLNEGQHVHLEGRVEPVHDPSMRVEWYHEGKALQSAARFHTTFDFGYVALDITTVYAEDSGEYTCRAFNHMGEAQSSVSFKVEGKEGVITESARPEGLEKIRELEDSARVGRQVSEEVRTFQRPVFTQPLQNLDNLTENETAHFECRLIPVGDPNLKVEWFRNEKPIETSSRINRTHDFGYVALDITGVRADDEGIYMCRAYNDLGEAVTTASIKIKSHATIQMETQHPEGMKKIQALEDRKPAGRGDEADKVYEKPVFTATLAGPAQIMEGQSAHYECRVVPVGDPNMRYEWYCNGVELKMGSRFKTTSDFGYVTLDILQCVAEDSGVYMCKAINLAGEAVSSCSTRVLAKDSILGDVLHPGWETIKLREAQWNRVPQTPTSPEALEPPMFTKHLESQERLQESGTVRLEAQVQPANDPHLSIEWFKNSIQLVTGTRIRSTFDFGHVTLEISGLREDDSGIYTCKAVNRVGEAVSTCNIKVFGRDWLIGESMHPEALSKIAKLEQPTAGPGSPDEPTFDVPVFISHLNNVECREGDTAHFECKVQPCSDPTMKIEWFINGKPMQAAARYQATYDFGFVSLDCTHCYAEDSGIYMCRATNAKGSATTTGTLTCISKANLTTPSTRRAELALRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NV20</accession>
    <name>A0A3R7NV20_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione transferase</fullName>
            <ecNumber evidence="1">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014459</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GST superfamily. Sigma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002808">
        <property type="protein sequence ID" value="ROT67462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NV20"/>
    <dbReference type="STRING" id="6689.A0A3R7NV20"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF224">
        <property type="entry name" value="HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="81"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT67462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="218" mass="25111" checksum="4693F3F0B5064426" modified="2019-04-10" version="1">MTYQLKYLSLRARGEAVRWVLKVAGVTYTEETIDIFREWPGRKHEFKFRKVPELVVDGKPLHQTTVICRFLGERHDLASGDLWTTTRQMEVVEALHDLANSMASALMARVQGDEERQKVMVGLAEAQFPVVLSNIEERITNKGWILSQQMTWVDVFIAAYLDVYENYFPGEVAKFPLCEALRRRVQDMPVIKAWREERPPWHPFEDPQGLVAPSGGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P4J8</accession>
    <name>A0A3R7P4J8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001798">
        <property type="protein sequence ID" value="ROT75229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P4J8"/>
    <dbReference type="STRING" id="6689.A0A3R7P4J8"/>
    <dbReference type="OrthoDB" id="10035275at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="58577" checksum="98F43F39DE8BC3E3" modified="2019-04-10" version="1">MALLHRFVKLNDRGNTHVFSFVVTRSVTRDLHRDVTSKELTYGYQRWAITFSRSEKVLGVYLVWRNPCEGMRVYIDFTFTLLNREHFSTNEAFTGKQVKFTFDSPAQGNRRLINMEDLYSRNFTDENGEFQLELTVANIRTVFEAELRVPPPINGGVANRKENRFESPYFHFGHYDWHVSVTSSSGLDGRPSVQLRRLTGFDHQCRVRYLMVVGEGERRADSGILDQLSDHEGRTPGWSPARTRLHDLVHKGVLRLYLEMILANTTSEVRLQPLAANTTPVQCYDRDKQAWALEPDLHSDMFRLRLVYNDVHNVPRNHLRYVCWNAYLLRRASRGYLESVCLTNGPFSNYYAQESTDDGIMMESDVTVKEIKEGPSSYLDERKELTVQIEWVESLLLFQATYHKYDDVTRMHNYQMRREISALEAENFSLERQLFSYQKSIAYAHSRGAVVDDPSEPNDYPHENYSNGKRDYDTRDYSTRDYDYAYNDLPERSFSTDTEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCY7</accession>
    <name>A0A3R7PCY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002867">
        <property type="protein sequence ID" value="ROT67006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCY7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="597" mass="64031" checksum="0791E8693288A2F1" modified="2019-04-10" version="1">MSGRGDAPSSTISSSVGFTVFPFSLQSGSQSSLFLFNRVHKSSFFSQSFFAIEVLETPTFLAVSRWLRDCFASCSFRSPCSLPLSSASSLSRPVSSFLSSSSPPLFFTCALTARTSLLSSSLTCLLCRSPVRILPLFSSSIFRSEISPPPASPALLASSRISPQRHLFRPPFSALIPTSLLPVRLSGLTLHSSRLLHPLPVVSFVSLSRWSCLCSPYRDGPVLSRRPSLRLCSVGRLLLIRFQSYAQQGHISPSLQPSPDLTSETVIAYETRWKYCLCVPPATQTIAEAKALHLNELPEGEVKEVPPSEAEGEKRYSASSAAPKAPPRENVRRLTLDLQASGHRETKEGAVTFRSVSAWRHSPPPSFSLPPRSPFLLHPSLLPSLPPYYIPSLSPSSVLPTSFLLFFLVPSSSFLSFLLLFLPSYPPPPSIPPLSSSYPPSLLPPLLPSHPSPSLSLPPSSFPPSSPSSASPSLSIPPLPSLSIPPPPLSPSLLPFSLHPPPPLPPFPLSSSFPLSLHPPSPLLSSPSPSPSHPPPSPSPSPSLSIPLPPLSIPSFLSLHPPLSPRPSLLLSPHPPPSPLSPSSISLLTPLTRKLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDC6</accession>
    <name>A0A3R7PDC6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000797">
        <property type="protein sequence ID" value="ROT82611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDC6"/>
    <dbReference type="STRING" id="6689.A0A3R7PDC6"/>
    <dbReference type="OrthoDB" id="64893at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113">
        <property type="entry name" value="AGAP001705-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21113:SF4">
        <property type="entry name" value="CHITIN-BINDING TYPE-4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018725173" description="Chitin-binding type-4 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="2">
        <location>
            <begin position="18"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="286" mass="31184" checksum="CD759B27277AB0EE" modified="2019-04-10" version="1">MVEKLIMLLMVVGGTWAHGRLMEPPSRASAWRLGFETPIDYNDNEGFCGGFSHQYYVNDGKCGICGDAWELSPRPHEVGGKYATGTIVRQYQEGEVIEVTADITSNHRGHFEVRICPTPDPEATQNCLDLHQLELADGSGFKFNISTDVGLHTMHVKLPTGLTCAHCVLQWRYVTGNNWGFCDDGTGMLGCGPQEEFRACADVAVSSASARTSRSSFRGSRPTPSEDLALERRIHPKFRLLPGGSSASGIECHGVGEWEGVPGVAVWCAKNCLGTDYCPPAQCRCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF12</accession>
    <name>A0A3R7PF12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative Krueppel-like 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018041</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003337">
        <property type="protein sequence ID" value="ROT64034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF12"/>
    <dbReference type="OrthoDB" id="6591996at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001963">
        <property type="entry name" value="Replication initiator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001498">
        <property type="entry name" value="Zinc finger protein 404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT64034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="52159" checksum="87B239F7045F24DA" modified="2019-04-10" version="1">MQAQAPAPVEEEQNIDQLMVGSEPPYECKICGKGFAIPARLQRHHRVHTGEKPFKCEFCDKTFSVKENLNVHRRIHTKERPYKCNICDRAFEHSGKLHRHMRTHTGERPHKCESLDRHIRDHSQEPCSSRKQQPAKQAEPRQQWQTSSPAMTATDSSSHSSPTNSSPTNSSSPASVSWDSESAEQQLPFREFRRPSEGPVASGPEVYTCPGYDNIGSRSPGYVSDDSGRGASPVSDTLSPPRSPITSGPPLNTQLPQPPHIIDAPPMAPRTPEDYNMFLRRLYPSLVVPKPEPSRFDNQRMAVFTTETGERVSCPYDLLLALQGNKSMYLEQRMAEQEALRRQQQQLEEHYMREETRRRREAAFFETVERVLKALVGKERLERLGHPHIPVDEVLMKTITLMGSQPCKEPSLYAMDRIKVNLRLLLECSVPDQTMWVKFGWRGKPIEEIVAEFLHYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF13</accession>
    <name>A0A3R7PF13_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytokine receptor-like factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002576">
        <property type="protein sequence ID" value="ROT69322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF13"/>
    <dbReference type="STRING" id="6689.A0A3R7PF13"/>
    <dbReference type="OrthoDB" id="9984427at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="194"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="454" mass="50364" checksum="002D555A13DF1A3F" modified="2019-04-10" version="1">MAEVEEKASSTSERLREEYRRHVQSQISHDLVDTISMLEQHQVELLQLCDQLKQAKKQVTDSASDTKATINAVFEEFIAAVNETVNDRRQKLLGEVQQMEDEALGPLDQCERILESRVREAAERLEQGKRLEKHGGVMAKDTVMRFQEEAGAMTNLPEVPVLCAVPCISVEFPTDPTLIEEVREVIEQAGNVSRMGPVQITNIVERPGALLVTWEEVDEDVSDDGLEFCLQCSNTGATDPHTALFHTKYRGPDYSFLLRDLKSGESYLLRVASRREGSRSFGPWSLTQSAVTTIPHFRWQEDGCSGWSMADEGRLATKVTSDLEVLHSKGPLITPGTSVLFKVVSGGVGCSDEGLGLCCRPVTGPEQLLLPGTLFLSAQGCVFLDGVSRVTRLPAIQEGSQVSFAVEKVSSTKVRVYIESQDKQVTYEWAVPDVQEGLYFVATFGEPKWRISVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF37</accession>
    <name>A0A3R7PF37_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA polymerase II-associated factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003311">
        <property type="protein sequence ID" value="ROT64168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF37"/>
    <dbReference type="STRING" id="6689.A0A3R7PF37"/>
    <dbReference type="OrthoDB" id="10260285at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="50818" checksum="30B2D2D1C7C26097" modified="2019-04-10" version="1">MPPTVNQNHSVDRDKRPRTGERRSDLVSRVKYCNTLPDIPFDPKFINYPFDSNRYVRYKQTSLEKNYRYEVLTEHDLGVTIDLINPEAYTPQSNAQLHPTDERLLEDDILTPQDAKRSRHHHVNVSWLRRTEYISTEPTRFQPQTMEKIEATVIFDSDPAPVGRPMPAQLEEMSQAMIRGVMDESGEQFVAYFLPTDETLKKRKRDAEENVDYMDEDEYDYLMAREYNWNVKNKASKGYEENYFFVLRDDGVYYNELETRVRLSKRRLKQGQQPNNSRLVVRHRPLIAQEHKTQRMSKGVDRAHARGAGQVHVHEASQEAVPEASHAANLAASPEVSHAADPAVVQEASQEVGQGASQSQGLDLVLLRVQRIQRIQVSLSLQVQNSLPIPLTFKVPKCIPARSERSKKCKLQICEVSCIEQIGQIKQAESKPIPITARLSGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PL26</accession>
    <name>A0A3R7PL26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative charged multivesicular body protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_011744</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002485">
        <property type="protein sequence ID" value="ROT69998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PL26"/>
    <dbReference type="STRING" id="6689.A0A3R7PL26"/>
    <dbReference type="OrthoDB" id="441172at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF5">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="174"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="23995" checksum="3D878F213894232F" modified="2019-04-10" version="1">MGSLFSKKPQSKVTEQDKAVLQLKSTRDKIRQYQKRSEATLEKDRQLAKQLLQNGKKDRAKLLLRKKRFIEEQLTKTDGTLENIEKMIQDIEFAQIEMKVVDSLKVGNEALKQINEMLSIEDVERILDETQEAAEKQREIDALLSGGILTDEDESAVEEELDALIAAAVEKQLPEAPSAAENPEVELPDVPETLPEPAKEKVKTKERVAMAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PL87</accession>
    <name>A0A3R7PL87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001765">
        <property type="protein sequence ID" value="ROT75494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PL87"/>
    <dbReference type="OrthoDB" id="6379454at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018545146" evidence="2">
        <location>
            <begin position="30"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="29273" checksum="4C4B28B6092586B3" modified="2019-04-10" version="1">MTLPRDLRFLWMSCWLGVFLCVGISSVCGGSARHVYVRCIKDEDDGRRDHCQLRREGEDKMQSVAVCVLVLAAGVSAVPPAGGFAASPWADTSMCSPTDPPAVCQLKKGQCSPLATVFSPPGGPVKAVTSCATATGVVLGPQFYMSIGKAFSSGNLESMVDMVSSDSTEATVMRFCFVNATGLLNSDLLADFISCLRSACMASVTVPATAGGSPFMGSSPFPMMSPYMGSPYMGSPYMGSPSGMKSSPYMGSPFAMKSPAAVGAKPPKKASPKMASFPTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQJ0</accession>
    <name>A0A3R7PQJ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001959">
        <property type="protein sequence ID" value="ROT73965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQJ0"/>
    <dbReference type="STRING" id="6689.A0A3R7PQJ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="791" mass="90865" checksum="0E57D12FF6F15ACF" modified="2019-04-10" version="1">MEAGWQEAEWRQMEAGEAMEAGWRQNGGRMEAEWRQDWRQNGGRMEADGGRGGRMRQEWRQDGGRIEAEWKQNGGRMEAGWRQNEQNGGRMEAGGARRQAGWSRMEAEWRQNGGRMEAGWRQRQQDGGQAGMEAGWMGRMRQNGGRMEADAGMEAGLEAGWRQDGGRMEAGWRQDGGRMEAGWRQNGGRKADGGRMEAGWSRMEAGWSRMEAGRMRRQEWRQNGGRMEAEGGRMEQEENGGRMEAEWRQDGGRIEAEWRQDGGRMEAGWRQNGGRMEAGWRQNGGRMEAGMEAGWKAEWRQDGAEWRGRWKAEWRQDGGRMEAEWAEWRMEAEWRQDGGRGRMEAEWRQGWRQDGGRMEAGWRQDGGRDGGRMAGGGSMEAGWRQNGAGWRQDGRMEAGWGQNGRQEWRQGGRMEQDGGRWRQGGQMDGAGWSRMEGWRQAEWIGGRRMEQNGGRMEAGRQNGGRMEAGWWRQDGGRMEAEWRQDGWEAGWRQGGRMAGQDGAEWRQDGAEWRQDGGRMEAGWRQNGGRMEAEWRQDGGRGAGWRQNGGRMEAGGGRGGMEAEWRQDGGRMEAGWRQNGGRMEAGWRQNGGRMEAEWQDGGRREQDGQNGGRMEAEWRQDGRQEWRQMDGGRMEAGMEARMDRWRQNGGRMEAEWRQDGGRMEVEDGGRMEAVEAGWRQDGGRMEQDGGRMEAGRQMEAGWRQDGGRMEAGMEAAGWRQNGGRMEAGWRQNGGRWRARMEAGWRQAAGWRQEWRLEAEWRQDGGRMGRMAGWSRNGGRMEAEWMEAGWRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSN6</accession>
    <name>A0A3R7PSN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000974">
        <property type="protein sequence ID" value="ROT81433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSN6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="532"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="589" mass="69777" checksum="E1935ED03E179DC3" modified="2019-04-10" version="1">MRLPPSFYFSSFPSSPSSFPVFLCVSLPHFYFSSFPSSPSSFPVFLCVSLPHFYFLLFHLLLLLSPFSYASPSSFLFFFFSILLFFFPRFLMRLPPSFLFFFFSIFSFFFPRFLMRLPPSFLFFFFSIFSFFFPRFLMRLPPSFYFSSFPSSPSSFPFSYASPSLIFIFLLFHLLLLLSRFLMRLPPSFLFFFFSIFSFFFPRFLMRLPPSFYFSSFPSSPSSFPFSYASPSLIFIFFLFHSSSSSPFLCVSLPHFFSISPSLIFIFLLFLLFSYAPPSSIFIFLLFLMPLPPSFLFFFFSFPHFLMRLPLLFSLFSPRFMRLPPSFLFFFFSIFSFFFPRFLMRLPPSFLFSFFSIFSFSFPVFLCVSLPHFYFLLFHLLLLFSPFSYASPLPHFIFLLFHLLLLLSPFSYASPSLIFIFFFSIFSFFFPRFLMRLPPSFLFSSFPSSPSSFPVFLCVSLLHFYFSSFPSSPSSFPVFLCVSLPHFYFSSFPSSPSSFPVFLCVSLPHFIFLLFHLLLLLPPFSMRLPPSFLFFFFSIFSFFFPRFLMRLPPSFLFFFFSIFSFFFPVFLCVSLPRLPASLSRKEKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWZ8</accession>
    <name>A0A3R7PWZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative parathyroid hormone/parathyroid hormone-related peptide receptor-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003820">
        <property type="protein sequence ID" value="ROT62128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWZ8"/>
    <dbReference type="STRING" id="6689.A0A3R7PWZ8"/>
    <dbReference type="OrthoDB" id="16753at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017046">
        <property type="term" value="F:peptide hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017983">
        <property type="entry name" value="GPCR_2_secretin-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00650">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="7">
        <location>
            <begin position="84"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="28523" checksum="6E984E6537A86798" modified="2019-04-10" version="1">MRLAVSPPAATGDRRTGGAQTGVAERETEAESTRSSYSSITTTQVSVTRGSRRSPSKSLSIHRQRFRSDARAALTKGCPDAQRSLPLGCVGVWAALRATMDDWHCWTVHNKRWIFWLCIRIPVAISNLINFFFFLNVVRVLVLKLKSSISAESMKYRKLGKSTLVLVPLFGVHYFVLWGLSTSTNPYVELAWLFLDQVFASFQGFFVAVLYCLMNGEVRQELRKLYNRWYKGDPLVITSQSTLVSHTKTYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1S2</accession>
    <name>A0A3R7Q1S2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000637">
        <property type="protein sequence ID" value="ROT83753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1S2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="49536" checksum="30E62D05F8758A52" modified="2019-04-10" version="1">MPTGISLLSEPASLVSYPTSSTSPLSDLAPRLLSRRLLVSIRLPPALPIRTCSLVSYPTPLCSYSTALPLLYLDPSSSLSEPLPRLPIRYSPSRALTHWLRRPIATSSPLSLSDAFPSLLLDCPRRPLSDLHSSSPIPTSSSSLPNLLPLLSRTLHPRSPSDRSFVSLSDSAILVLLSDRFLVSIRPLLVSYPTASYPPTRLPHSSLRPPPPLIQPLPVPYPIRSIVSYSICLLSPIRPLSRLLSEPPLSYRLPPRLLNPIPSRLLPTASVSYPTTASSPIPTAPRLLSEPLLVSYPTASSSPIRPPPVLYPTAPRTDPPPLVRPPPVSSPSPRLSFANLLFYPTSPRLLDRPLLRPPPRPLHRPLLVSYPTAPRLLPSRPLVLSDRLLVPIRPPSSRDRPSFDPDTASSSPIRPPPRLLSDRLLVSSLGCVVDECGGGGSIYIGCAFFSVIKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q327</accession>
    <name>A0A3R7Q327_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002829">
        <property type="protein sequence ID" value="ROT67256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q327"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018649152" evidence="2">
        <location>
            <begin position="19"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="41114" checksum="D99FA1C123629EFC" modified="2019-04-10" version="1">MASSFRSLLLSLSTPSLALLPSLYSLSLVLTSPPYSLLYLPHHSLPPFPPFSRPLTSSLSFPYPSTLLSLPLPLSPVSPPRPSSTSLLSPPRPLPLSPPAPPSHLPSSPLLAPSLCLLLPLPLSLYPPFLAFPLSLLPLPPPSSNSLLPSSPPPSVSSCPSPYPSTLLPCLSLCLLLPLPLPPLPPSSPLLAPPSVSSCPPPSAPDTFPSTILPSNLDLPPPSYSLPPIQSRPPPPPRPVLTSPYPPSRPHGPGNSPEVPPWAESSRGDHTWLHRLAVYVRRLFRNECRPAQVMSGRGRGRLQGPSARTDVDTGRMNEAICGGPSLPPVNTGDNERKTRIKPRPKGASRAECPGIASPPPPPSDRLCVDAVPISRSSENRNRRQSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4K9</accession>
    <name>A0A3R7Q4K9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative peripheral plasma membrane protein CASK isoform X11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003395</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAGUK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000146">
        <property type="protein sequence ID" value="ROT85956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4K9"/>
    <dbReference type="STRING" id="6689.A0A3R7Q4K9"/>
    <dbReference type="OrthoDB" id="336747at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12035">
        <property type="entry name" value="SH3_MPP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.10:FF:000002">
        <property type="entry name" value="Guanylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000146">
        <property type="entry name" value="MAGUK p55 subfamily member 6 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.10">
        <property type="entry name" value="Guanylate Kinase phosphate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050716">
        <property type="entry name" value="MAGUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23122">
        <property type="entry name" value="MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018590768" evidence="4">
        <location>
            <begin position="27"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="101"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate kinase-like" evidence="6">
        <location>
            <begin position="225"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="45726" checksum="E3C725101BC56C9D" modified="2019-04-10" version="1" fragment="single">MPVILPSSFSLSVITVSALFLPLTQGITLKMNEEGRCIVARIMHGGMIHRQATLHVGDEIREINGMPVANQSVDILQKMLREARGSVTFKIVPSYRSAPPPCEIYVRAQFDYDPLEDDLIPCAQAGIAFKTGDILQIISKDDHNWWQAKKDPNGTAGLIPSPELQEWRTACLAMEKSKRDQVNCSFFGRKKKQHKDKYLAKHNAVFDQLDLVTYEEVIKLPSFRRKTLVLLGAHGVGRRHIKNTLIASHTDKYAYPIPHTTRSPRKDEDNGKNYYFVSHDEMMADIAANEYLEYGTHEDAMYGTKLETIRKIHSEGRMAILDVEPQALKILRTAEFAPYVVFIAAPSLQNMTDYDGSLERLAKESDLLKQAYGHFFDLTIVNNDIEETIRQLEKSIETMNMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q7G7</accession>
    <name>A0A3R7Q7G7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Importin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002418">
        <property type="protein sequence ID" value="ROT70489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q7G7"/>
    <dbReference type="STRING" id="6689.A0A3R7Q7G7"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="194" mass="21511" checksum="4F56D1DEECFB6DCF" modified="2019-04-10" version="1">MFRVLEWQRGWQGTVAGSGQDGAREHGRGTLGRGVARGGGVCAQAIPLLVQVIQSPDARSEVNLNPTENAIAAVTKILKYNNSAVNVDEVIPVWLSWLPVWEDTDEAPHVYGYLCDLIDGNHPLVLGPNNSNLPRLMLIFSEAFRREAVEKEAEVTQRMLNIVRQLQANPEVFQACISQLSQEQQLALHKYLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QEJ2</accession>
    <name>A0A3R7QEJ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003176">
        <property type="protein sequence ID" value="ROT64862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QEJ2"/>
    <dbReference type="OrthoDB" id="6373398at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="787"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="822" mass="87621" checksum="A0DE0762EBDB447F" modified="2019-04-10" version="1">MRPPDSEHGPLISPDPDVNGNHEDVPLEASAPTDEEDPEKVKKIIEEPNTKKDPADPPASDSPKDSKTPNGYPKEKDEVFVPVEEVVAPAKISHEKETVPVINHVAPVGLVAPLGLVVPAKTEPSPKPTQPEEPENKATPKTSQPEAKKPESQPPASGSPPAPVYVPVPLAVKKPVTDSDEEDGLLLQKCSPHDDSLDPEQCPQLTALPEQGKSTPEPDAEALPVQNPPSSEPSAPEAPETPTPVKAAEASPQTEGPEIVVVPKPDADYGWKENIVPVKRAPDSVPPPVVEQPATPLMKEDVENLQPVHKVDVPITADIEELDDPVEPVFEVKDISRDLKASPPPKPVREEKPIEDLPPAAAAKNDEPVETPQGLKSKEIPVAVTSLPEDPVESSDDSVEYPPVVYLETRQPTQDARPASECSGSSEEALPPYPDSTPEKETTAKNGREKAQVEGPAAAKEEDEGSERKTKPEVVESPIITKAPLQTDPGLPLAMPTAVPTNKPMNDAPDAPLEAYIPDLNEEYGLDPMNPDDNSLAVIKEEGSTCTESETDSSEPEVTEYSFSSGPTAPTTSDILADEVSCSMEPEVTKYSVISDVEASIPPEESESSDTEMSETETDSVVLSTSVDPEEKANASLDQKPGNPKPCQSEPDSSTNEVLTTPNTTHQGDSVPVTPSDSVCTQLADSTNAPSHVSLSSTDDSEDESEGAEAELELREEVVEIPTATQNEPSESVTASSSDLPTSSSVVEESSAQVTKNKNPPERLRTEEKKNGTFQSVPDSTDNDFMSTPSSSPCSSDLSDDEVTTSTPKKSKIPRLVSHQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QI31</accession>
    <name>A0A3R7QI31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001219">
        <property type="protein sequence ID" value="ROT79609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QI31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="41969" checksum="565BCF3038A01786" modified="2019-04-10" version="1">MLQGTTRQDFLSPAPPPVGSPPRRSPSPASAPARRSPPPAGSALRPRPPRAQALRPPRLPAPPQPLRPPSAPRAAAASARLGSPPRAALRRLGSPPSPPASAPPRRAPPPASVPRPRSPSARLVPRPPQPLRRSVPPAAAPPPRASPPRLPARRSPSARLGSPRRSPSAASVPRPAAASAARFPARSPPPPRLRPAAALRPPLRRASAASAPPAQPLRPPRSPPAGPSAPRPAAAPRRSPSALGSAPAQPSARLGSPPRRSPSARSSRPAQPLRPRSRPPQPLARLGSALKHKSPARRRDVTGRRLPGQEAVRPRRRFIERKLTTRHRQRRSIYRNDLPTDRKLTSARRHLVTRTCGEINRLLRGRLVGRITSSWGSRLRGSEAASKASSKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QIH0</accession>
    <name>A0A3R7QIH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002662">
        <property type="protein sequence ID" value="ROT68484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QIH0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="661" mass="66640" checksum="A9650637EA4F41DB" modified="2019-04-10" version="1">MNLARRTWGWMASRRRKERLLCIILLIILVAAFNAPFQGNHLQEFDTPNAAERAVSTPSPKKAVNEPLCRPSLRGLGLAALSCGAQGLLPAGPGLFPAGLRSGSHSGLSLLSAGPRVSLRGPGFLPTSLARVLSLCQVSPAGGQGPSLLHGPPPHTRLLPGPQGLLRCGAQHTHAQGLPPPSLSSVSKLRKPPRLATPALNQNLSPCGPRTRFDSPAGPSARLTGDLLADYQLVTHTQFSMHSGQSLPRGPGSATAGPRVSPCGPGLSPRPGGCLPAAQSLPARAQGLSLRARSIPTGPGSLPRGQPSLRGQGLSLRAQVSPAGQVSPHPAPLDPAYAVLHAGASMISLAPALSLSSRVSRACACASRPCYTEVALRVAGQVSPCGRQSAGLVPIGESHLPRGQRIYICPSIAAQHSTSYLACGPLSLLSVLPRVLLRAPQRAPRSLLRPHGLLPRAQFSPLQGPGSLPAAQTSLPAGPGLSLRGQVSPCGAQGLSLRGPGSLPAGPGSLPAGPRVSPCGAQGCLPGQGSVPRGPGSLPLPAGPGVSPGMVLSPAGPEVRLPRGLGSLPCGARVLSCGAQGLSLPGPRGAGPSPWRAQGLSLAGPRVSPCPGAGPGGPGSGAQVAARVSSLRGQGLSLALLILPRLCLGKDPCPSGVQEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QK05</accession>
    <name>A0A3R7QK05_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein kinase ULK3</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Unc-51-like kinase 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_025533</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01000991">
        <property type="protein sequence ID" value="ROT81310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QK05"/>
    <dbReference type="STRING" id="6689.A0A3R7QK05"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14121">
        <property type="entry name" value="STKc_ULK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000804">
        <property type="entry name" value="Blast:Serine/threonine-protein kinase ULK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF65">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ULK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 16" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="13"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT81310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="482" mass="54704" checksum="52524C239AF68006" modified="2019-04-10" version="1">MAAAAGPPKIPNYIIAEKIGSGSYADVYKAYKKGITREVVAVKCVTKSTLSKWALDNLIQEIGILKKLKHEHIVEMKDFVWDDNYIYIIMEYCGGGDLSHFVKSKQRLPEAVCQRFLQQLASALRYLRNQNVSHLDLKPSNILLSSKRNPILKIGDFGLAQHMPEEDTSSTMKGSPLYMAPEIVLNRQYDAKVDLWSVGVILYECLFGKAPYSSKTLQELLDKIKRDKPIEVPYGTNISPECRDLLQRCLERDVSKRIDFEDFFAHPFVDLEHKPGPESISKATELLTSAVNFDECQEFEEAFRHYSKALQYLVPVLHVEKDSVKRSALRHKITEYLKRTEALKKIINCEKDGIKNIRVPTISRQDSSSSTTYQGNREELIRLSGTTPQIIAAMEIATTGDMYAQEGNYAIAQEKYELALGKLLALMQNEPKGRRKELLREEIERWMSQAEVVKDLKEGGTSKEAGASTNNESYDEKGCFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLB0</accession>
    <name>A0A3R7QLB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine proteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010626</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002346">
        <property type="protein sequence ID" value="ROT71077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLB0"/>
    <dbReference type="OrthoDB" id="7726766at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="161"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="374"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="69551" checksum="A59ECD0BA448D702" modified="2019-04-10" version="1">MDARSSLAVCLEPQSLSPSLYPLHTQPEIPLRTVPTSFITLSILPGSSPIQTSPFIRPKDVTSCRRDLGKVSFFPVVKKTGSKELFFRPETSLLPLGACRMWKSGWLLLVVLDIVFGQGKTVPASILPNITNLQQQNEDFINRFINKFNFVLPETVTEATCGGTTNTHKTVWQNPMYPSIEGGLPSLCPLTVNVPPNTCALKVHFIDLDFAPRFFSYLTGFCAHDSPSFKASYKNGITRPLCSDHSGSEGILTVNPDDAEPILLLLQLDPSITFKFQINNEVPPLRRSGLADDPEVKVDVEAEYDADLELEEEEEAAAAREGRARKNKPDRGGNAGRKKAIVKRLKEDMNIFSQAFASAIERGRLGTRSEKGRILGSPARVAEWPWMVAIQLNAEVTLPLFGGPFPFPQPLCSGVLLDDTASSPPPPASSASSRDYVDQRSANLRALVGEYDVSTNDDTTSFNVSVSKVTFPLTYDPIYLKDDFAVIELATPVPFTPTIRPICLPVDYNLFPSSEGTVTGWGEDGVGGTVTVLQEAIVEILNDTTCESVIESLFQLFTIIPGFDPSIVDSSAYTCVVGTNFGSPVCSDDKGTPLVRKDRTGAYFLTGVQTNANSCGVNFPNTFTRVDPNSVFMNVALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QME2</accession>
    <name>A0A3R7QME2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000641">
        <property type="protein sequence ID" value="ROT83726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QME2"/>
    <dbReference type="OrthoDB" id="6374429at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="44389" checksum="8EEA3ABE2CCCDCA3" modified="2019-04-10" version="1">MADKQESGSSASESVPLTEDKTHFWVERESQKSGKNEKWGDTKEMKGDEEDADKEERVECDLSVTHTRGSQMTVEKFMGLEKFVQSQQSLVSNASTSSDSLTVNTSMTSFNEPVISDVSATYSLSSTDDSLENYEAHMSADSADEYQSMMTGAIKKYFGAEVGPPGGEGTKQRRAALWLESIKYLWGILFYGLLVLSILFLATSIWMTQRVKEREYGYNMLYWSIPFVVVMSLVVLAWQGTWHTLLALGYGNGDHIQDRRNFIEFAQKKQLVYTVRGAIYAPTYPDPTATTSNSCSTSKQIPPSYSVVAYESEFDSDLYFDSDLEPDGQYRRSITPLKEIEDPEKRERRNIYTRKAWRGRARDLVGGLESTPQGFLRRVLGRLEEDGGAGKCIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRL1</accession>
    <name>A0A3R7QRL1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Persulfide dioxygenase ETHE1, mitochondrial</fullName>
            <ecNumber evidence="13">1.13.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Sulfur dioxygenase ETHE1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_005823</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>S-sulfanylglutathione + O2 + H2O = sulfite + glutathione + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:12981"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58905"/>
            <dbReference type="EC" id="1.13.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer. Monomer. Interacts with TST. May interact with RELA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.18" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01001749">
        <property type="protein sequence ID" value="ROT75645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRL1"/>
    <dbReference type="SMR" id="A0A3R7QRL1"/>
    <dbReference type="STRING" id="6689.A0A3R7QRL1"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070813">
        <property type="term" value="P:hydrogen sulfide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000013">
        <property type="entry name" value="Persulfide dioxygenase ETHE1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051682">
        <property type="entry name" value="Mito_Persulfide_Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43084:SF1">
        <property type="entry name" value="PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="16">
        <location>
            <begin position="59"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00065219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00067300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00077964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT75645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="287" mass="31484" checksum="132CF21009E8B5BF" modified="2019-04-10" version="1">MAMLGFLKSAGRVALARNPSPFLCSSLKQAAVPSLFRMMSALASQNDVLFRQLFDRETCTYTYLLADTQTKEAVLIDPVIDLAERDAKLVGELGLELKYVMNTHVHADHITGTGLLKKLVPGCQSVIAEVSGAVADVLIKHGETVKFGEHELEVRSTPGHTNGCVTYVSHNLKSVFTGDALLIRGCGRTDFQEGSAETLYESVHSQILSLPEDYVVYPAHDYKGNTSSSVGEEKQFNPRLTKPKDEFIEIMNNLGLPYPKKIDISLPPNKVCGLYNLPDELAAKLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QXF8</accession>
    <name>A0A3R7QXF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024988</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000910">
        <property type="protein sequence ID" value="ROT81855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QXF8"/>
    <dbReference type="OrthoDB" id="6393648at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="28"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="35219" checksum="4CC69D5649376A6D" modified="2019-04-10" version="1">MASASSDSPGRNQRAPALDAQAQRRSARRNTALHIAASQGHLHVLFTLVKLGAATNVRNGRGKTPKELLKGTSTTANYDMEIFKGISLIKIMEKYLAAEKGKASLRREYMSFQLCLGDYNVFLLYRRCAIVAKTCFATARDETNSRPWLPGIADLHVRLIRRQGPGRLKRSISFQEEHKAELRNVAENQQEKEAEILRMQNEIAGLKETVASRDEKIKSLEVPAQDTDRGPFQERRGGTARKGDPGSRREQRTRHGSFRSSRHDKVITGTKYEGTAESQKRAAPEGGRGGEPTQGSPGGAQVPRQEGQDTEAAAKGERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QXL0</accession>
    <name>A0A3R7QXL0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_024746</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000884">
        <property type="protein sequence ID" value="ROT82096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QXL0"/>
    <dbReference type="OrthoDB" id="6378669at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018719631" evidence="13">
        <location>
            <begin position="22"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="14">
        <location>
            <begin position="262"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT82096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="560" mass="62147" checksum="1A123F2DB4353B7B" modified="2019-04-10" version="1">MRPWLLGPWLWAALFVPAVMGARISLSQFVRINTGGVDGDSGISEPVGAMVAEALLEWARGCHLVLIRAGESPISGHVMRAISTRLWGGAVVVDVGTRAFSRRGQEDVAGNLWGEAAFPCRSLLLDLTGNATQFLGSLEFGFLKTSGVSLYPGMRTVLVGPQHQMADALQHPSLRNAIHAIYLALKDGVSKGVFVYRRCLYCDGGEMGVRLLDQWQLKSDPSRFPNPFSEEIGDFMGHNFRIVARFYFPTIDYTRDTDVNGTTVTLRDSLNARMLVTIAAKLNFTYVIREPKDREWGALLEGGNWTGLVGTLQQEEADFSMTITPTAPRLLAMDQARTPQSRRCMAWLCTVWLILAISVFATGVSLFVLLRAWSRLSGKPVFSLSTALFFSWGTVLEDPPPTAPELNGQGISKKNEENRFYYSVVVICLAILSVVAGSGYRSSLAAHLTVQLKEAEVNTFRDLTARRGWRWGSELLLGASRSYFELSTDPVVQEVFRRMETHELDENMELVLQGGYSFITTKFQNTAVVALQYTHARGYSPIHTSRVEYPKFAGTSWGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIP5</accession>
    <name>A0A3R7SIP5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Crustacyanin subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_019479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003566">
        <property type="protein sequence ID" value="ROT62666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SIP5"/>
    <dbReference type="SMR" id="A0A3R7SIP5"/>
    <dbReference type="OrthoDB" id="6332976at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018383718" evidence="3">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="5">
        <location>
            <begin position="48"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT62666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22463" checksum="65EE7B005CA56FC2" modified="2019-04-10" version="1">MRTSLLCLALVAVVAADRIPGFVVPGKCPAVDERMLYSQQKPNFQRYAGTWYEIALTNNPYQLIKQCVRNEYTYDGIKFNVRTTGTDANGNAITRKGQVLPNPFGEPHLSVDYEASWMAPYVILDTDYENFSCIYSCAGHNFGYYADFAFIFSRSPTLADRYYRRCEAAFMNIGVDPSRFSKTAQGASCSYNTNYRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9Y6</accession>
    <name>A0A423S9Y6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004427">
        <property type="protein sequence ID" value="ROT61007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9Y6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="42105" checksum="855C0962F8D5C0EC" modified="2019-05-08" version="1">MLPSSSLSLLSSPSTSPLPLFRFSETLPLPTLCVLLILSSLPSLSPLFPPFSLLPHPSLPAFLLPSPLPSSFHIFCASLSLLPLFLPLFNIFLFLACLSLFLPLFSSLLLSPFPPSSISPSLPSPSSNPVSLHLSPLFSALESSSLRSALFVSYLILFLALPSLSFLLHPLAFSHPLLSASLLSSPALFSPSSFAFPPPTSFPSLRLSFAPVLPSLPLSFSSSPILSPSSSHLSILPPLLPSFSLASPFPSAPPSIPSLSSPTLLLFSPFSLPPSLLFSLPILTLFPSSVPSPPSPLFSFSLLSLLLHSSPFLPFRFFLRTQSLSHLASRFLITLFPNPCNYFLRFLSPSYHPRFPFPSFIFHLSSSLPSLPCYLYVYSSVRFPPCPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEY0</accession>
    <name>A0A423SEY0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Deformed epidermal autoregulatory factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_019406</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003559">
        <property type="protein sequence ID" value="ROT62738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEY0"/>
    <dbReference type="STRING" id="6689.A0A423SEY0"/>
    <dbReference type="OrthoDB" id="6342663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.390.10:FF:000004">
        <property type="entry name" value="Deformed epidermal autoregulatory factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.390.10">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010919">
        <property type="entry name" value="SAND-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000770">
        <property type="entry name" value="SAND_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024119">
        <property type="entry name" value="TF_DEAF-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237:SF1">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10237">
        <property type="entry name" value="DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01342">
        <property type="entry name" value="SAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00258">
        <property type="entry name" value="SAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63763">
        <property type="entry name" value="SAND domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50864">
        <property type="entry name" value="SAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAND" evidence="12">
        <location>
            <begin position="129"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="13">
        <location>
            <begin position="435"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="335"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT62738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="497" mass="53097" checksum="C2DF5B9AD1E1EE51" modified="2019-05-08" version="1">MDASLGESPDGGTTELVVVPELDSVGLSRPHSVPLVKIVTAATQDQLNDVIDASPTRLGDVIDASPTRLGDVISTPADVTIAEVALGDDARSAMVEEGHSCSSGGITTPVPASSSEDSKATPVFAIEPDWREAAQDPVLLVRCKKTTGELVKNRFGSGSRGKCIRVGKLWYTPTEFEAHCGRSASKDWKRSIRFQGQSLLTLIEEGYLQVHATSCSCGACLDGDAAAGAVRLHRPYRRKKRDKFMIDTEVAAKVLKRTLSDDPGSSTPTVTLPVSGLGELTVVPGIVLGGGTPTTAVPTTPQGATAAPSSAGSPCPVSLSNLPLDKAWDRMNEVLLGLERSVSGARALLEELKDRTEQETLELRRKLLQEKDEAVTQAKLEAQLSNMTKPSEGFLVQVRDDDGNQSLQPIMLDSLISNVPTLKPAPPINGVKKKCVNCNRESELECSGCHNRAYCSDFCQRRDWANHQGECGRTSPPPGDPLSTVTQVPGYIFMLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFJ5</accession>
    <name>A0A423SFJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ADP-ribosylation factor-like protein 4A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_019187</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003520">
        <property type="protein sequence ID" value="ROT62941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFJ5"/>
    <dbReference type="STRING" id="6689.A0A423SFJ5"/>
    <dbReference type="OrthoDB" id="6339888at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051649">
        <property type="term" value="P:establishment of localization in cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT62941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="15598" checksum="80F5F81B828B868E" modified="2019-05-08" version="1">MDSWSRKRAGVARAVEGVVKRRKHIVLVGLDGSGKTTVLTRLKYRCYVATTPTIGFNHEKVWGGGYRWSCWDVGGGERLRPLWSSYTRATDGIVFVVDSASMGDMMEEARVELARVLKKSRASSVQLGMPSPPLLVLANSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJZ0</accession>
    <name>A0A423SJZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003233">
        <property type="protein sequence ID" value="ROT64558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJZ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="617" mass="67242" checksum="A673775FD87D4F19" modified="2019-05-08" version="1">MSYVTFHAHAHNNPRPPRPQTYPRHPAHRQITPTDKSTPDSCHNISTPPPPQTNPRPPPPRQSTHPRQQTNPRPPAHRQIQTPPPPLTNPPANPRPPRHRQSTPSPPQTIPPKTNHAHPAHRHSSAHPAHRQSTPLQQITPTPAHRHIRPPRQQTITPTRPQNPATPPTDNHATTPPQTNPRHKQITPTTPLTKSPPTNIHATAPTDKSTPTPPSATQPQTIHATDKSTPTPAQHIHCPTRQQKSAQPSAQRHPPATDKSTPTPPQTNPAIAHRQIPPTDKSRHRHPATETMPTPTNNNHAHAPRPPHDNPAPTATARDARLQGVGFLVAFFEVSRYPRRDLAALRQEQGLSLDAHESAGVRAGATHTPPAPPMTANPPVTPALQPCQEPSVTPVDLPRFEPAEACSEPCSRSPFTAVVACSRTPFVSVSAGVHSARLHPPLSPLAPSSTPFPPRPLLYPFFPHRPLPPTPFPPPAPFPLPPFPTLFPPAAPFPNPFPPRRPLPYPPLSPLSPPLPYPFPPPSPPPPPLPPFPPLPPFPPFPFPPPFPPPSPLPFPYPLPLPPFPFPYPLSPLPFPTPAPFPLPPSFPPPRPSPYPLSAHYPPAGRRRQGVNQVLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLN4</accession>
    <name>A0A423SLN4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_016879</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003131">
        <property type="protein sequence ID" value="ROT65158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLN4"/>
    <dbReference type="STRING" id="6689.A0A423SLN4"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="9">
        <location>
            <begin position="115"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase RNase H-like" evidence="8">
        <location>
            <begin position="437"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT65158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="587" mass="66200" checksum="D50CB3BFAEF889DC" modified="2019-05-08" version="1">MVNPIFDVIIGNIKGVRNSCGADAATQTGCVAITRSMEKRKGELTPLTSVSDLINSQDIVQEQKSDSSLESVRRKLAEKSLNRSFNEETCFIERNKRIYRRVLALNGEERLQFVVPARYRLAVFRLGHHSALGGHMGQKKTLDRIQAEFFWPGMGQEISRLVRSCDICQKTSDRGRVKPAPLKPMPLISEPFERVAVDIVGPIHPRASDGCKYILTLVDFSTRWPEAVPLRNIDAVTVAEAMVEIFCRIVRGPLQILRELWDDSGVDTEVKTTYTYVIDLANRLQSTCDLAKQELLKAQETQKAYYDRKAKKTSKLGSTSTTTYICAAAVIPESECDDGPVTAQSWQTETIDNVKIPLHPESREVTAFTSPAGLYQFRVLPFGLSNSPAVFNRVMRQVLQGVKGVEAFIDDILVHSSTFEEHLKILEEVFQRLQCANMTVKPNASQDGVGAVLMQETDGEIYPVAYHSRKLKSAERNYSTVEKELLAVVDGIKKYYFYLYGDKFLLETDHMPLESLRTSKNANARLMRWAMYLQQFNFAIRYIKGSANVGADFLSRLVENNWQDSEESLRSDQRGAQLCDGTKCMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMX7</accession>
    <name>A0A423SMX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein K02A2.6-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003068">
        <property type="protein sequence ID" value="ROT65587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMX7"/>
    <dbReference type="STRING" id="6689.A0A423SMX7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="44211" checksum="9A821761D7182F3A" modified="2019-05-08" version="1">MPFGLQNAVQTFQRFINDVTRGLEDVFTYIDDILVTSASKEDHASSPSSEDYKKRESVPPGLHFISHDRHLLHSDSDNEAVDALSRVTISVATLTDDAVDYHLVSREQRPDTSVTPIIEGQTSLERIKISNSRNDFLCDVSLGYPRPYILPSLRQQFFHACHQHHGIRAPHHLIRSKVVWPAINRDTFPIPDGRFQHIHIDIVGPLPMDDGCSYILTMIDRFTRWPEAMPIHDITAVTVTSSAPGSPTSAPRTPLLPTAAPRSELWCQLMILLGSKRIRTTAYHPCANGMEDLQWTTAEMVYRTMLTLPVYLSVKASNIEPGDLRQATLRTDDSDAQPTDETLSATGHIHTSRTPGLHPRSPLCPPYEGPFPDEDTVIIVRLSLMDLSTSSLNNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SND1</accession>
    <name>A0A423SND1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleoporin Nup37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003042">
        <property type="protein sequence ID" value="ROT65758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SND1"/>
    <dbReference type="STRING" id="6689.A0A423SND1"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037626">
        <property type="entry name" value="NUP37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22806:SF0">
        <property type="entry name" value="NUCLEOPORIN NUP37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22806">
        <property type="entry name" value="NUCLEOPORIN NUP37 P37 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="115"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="34256" checksum="C81DD42816B409D8" modified="2019-05-08" version="1">MEVNIAPALSVNTRTQVLALEFSPYEWSRGLLAVALPTSVAVYSIKFKEEGDGTSEECGQVWEWHVSSQPVCLAWSPNATLRAAPRCLQVTLGSTDHKVTQLTSDLGDSHTAQDILSHTDFVNSVTYNGDSGNFVASVGDDLTARVWDSSLQSQVAKFLLTSPGMVVRFHPEDPDLLLVAEKVGVLRVYSVAGGCSTLSVRCPGPLLSADWSIPDPSLLVAAGAKGLTVWNLASQQPRSEHVEVGGGEKVLNVAVCRSVTGLVATHAAPHTVRVTHLHSNKVPIAAHLKVVGGISWHQNLPYLAVGSDRRILFWKIDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SR11</accession>
    <name>A0A423SR11_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002913">
        <property type="protein sequence ID" value="ROT66650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SR11"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="45043" checksum="276F1FE3CC7AFBE4" modified="2019-05-08" version="1">MGGLESDCGNLRQFWRDRGRGGVADCYLPDNPNDKDPRRPQQNAHRPVSATPTIPTHAGGTQHDSRDDSAMKRVIRERQRQRGWGTAPALDRRRNWSRKQVIAAGRRRAWAGARGILMAGPQRRRHRTFPANRSLARFLSLPPADPCHGKPFRNPLSPPAERTPNTSPRSCERGGRGRGAGGALPALQKEPSGVLAFVSFFSFFFHCDLSPIVSSPYIRRSVIAAVAVSPIQEDPTSLFSRRKPLGTAQSLANNIQILLHSASSNDKCYSLYPGLALPVVAGADREPASPFLPTAENGARRERGDCTGPARSPRRRRTSRSCDNPRGCLTSRNTGEQRGYKILSHRGRHTSHPRPHPGNPVSLAFHVATSPLIPSMPQRPESRVEFVKTLNDLPSTPCMTTACAPKSLGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423ST74</accession>
    <name>A0A423ST74_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002810">
        <property type="protein sequence ID" value="ROT67415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423ST74"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="42673" checksum="4537B23962A626E3" modified="2019-05-08" version="1">MGDITSYLFGVATHDELDARFGDYERALSSVAGKFKATFGAIHTISDTVNSLNNVTRQLSIYTDTNAQLIAREQHFTLLLAHVSLYQSRVRLFVDHLNTLTHDLILAVHGSVMPSLIPPSTLDSFIRRISAETRFTPLFSMANATLLYSLLESFITPHDHTSLSFISSSALSSCSSVLSRFHACFDVFPPEHSYFHSSCHKALLSNGDVQSSCLFNQLNSTNPFLLTLPDLHLLYFFSATHVSISCGSNHADREVSAAFLLPRSCQLSARLISLRSSHSFHFAYSPTTPTLPPMSLDLPVTNVSLPLANVRKLPSYRDDTPDILTFAHSPHVTFGFPVFSTVIGLVIAIFGFLLYRHLTIRRLRIVSSASSVSDDPSGHQLPLSVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUD5</accession>
    <name>A0A423SUD5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MICOS complex subunit MIC60</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Mitofilin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_014156</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion inner membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MICOS complex subunit Mic60 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUD5"/>
    <dbReference type="STRING" id="6689.A0A423SUD5"/>
    <dbReference type="OrthoDB" id="10261039at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019133">
        <property type="entry name" value="MIC60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415:SF7">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15415">
        <property type="entry name" value="MITOFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09731">
        <property type="entry name" value="Mitofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="453"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT67763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="732" mass="80445" checksum="AD57C40E51AC19D2" modified="2019-05-08" version="1">MLRISSRIKPHVASKIARGHGAQRLQSTHSGGGGGSKVLIASAGVTSLVAGVVGYAAWSNDNRKSIENTIPGSGYVLGALLGPVMEPLPPKPVTKDVGLMKKKLDREKKKKKEEEVAPAVTEGEAAKLEPPAVVEVSTEPVKDDEVVLEQVSSETVPEGKVELEPTAAVPSEAEIAGISSDIAGADTPGTELIITTPGQPEKAPESSNEAPAVSDLETRLASGEIEQDVENATLTKVLEDLASAAQKQLTTALASAEDAAVIIRQHAEKAYLAIDAGQDKEILFAAVAELSEKKAEVVKTAQEKINQAEEAVEKLKEQIADGLSSGLTRDNKSLITAEESLAELKYAVENIKTIISQSERDSKVVSDYRNLVESGREQFEAEVRSLLPEVKLGETSDKLTRDELNLLIAHAHRKVLQLQNQLARLQTLEHDRFKEALNKQRDDDAGLLEAKVNASLEKQKQQLEVEYKRKVAQLREELESELRAQLKRQAAAHSDHLADVLTVQEKELESKWSELLQDKVQTEKDKYLSSVAVMQGQLDGLKNALTARADVDKAAYSARELWLACESLRSALRFTNFKYLFSGENSYLSAVIGAVSEEARTRGVYTEDALRERFIKVDRICKRVSMIGDNGGSLIKYMLSYVQSFLILNAFEYLPGSEVRDEEVPVDSLSVYDILARARYCLDKDDLLQSSVFDQDIIGTDLTIWKPRRLPSQTRARRLSVNTTCRLVIFFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SX89</accession>
    <name>A0A423SX89_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002626">
        <property type="protein sequence ID" value="ROT68854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SX89"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="473" mass="51341" checksum="8D257CA3094EEC9F" modified="2019-05-08" version="1">MAAPGGVLRRSARDPFPSPPLASSLPLLSPLPSPSRLTSPSPSRLISSPSLPSLLISPSRLTSPSLLTSPHHLPLSPHLCLLPSPLSLPPPSPLSSLISHSSYPSPSSSPRLTSLPFPTSLHNSLLPFPPVTPSPQTPPPLALDTNSLPPVLFPPLPYSHLTPSLPPGSFYTPSSPAPNDIRLLPLPALTPTLLPPPPKTPDMNPLPLTLPLPFSPHPHPPPDDTPPPTYLPYPHLPYSLPLPPLSPPLPLPRGGEEAKEAISAHPNPPSPPTPLRPSTPLRPILNPNTLRISRNLNLQEINALITNPIVSWHARDSPFLILLLPPLPSPHLPSLSPPPQHSLPLVRPCQSCRGLARCTVTQPLLPPSPISFLWSFPPPPDKSFISPTFFSRLPRLLLLRSLFFSFHSFLSSYSLHLTPFFIIIFSVHARITENHETCFCYQTFQRTEDAVDKALQSLPGRNTFTITNFPTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXS4</accession>
    <name>A0A423SXS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative urocanate hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002612">
        <property type="protein sequence ID" value="ROT69035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXS4"/>
    <dbReference type="STRING" id="6689.A0A423SXS4"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006548">
        <property type="term" value="P:L-histidine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1770.10">
        <property type="entry name" value="Urocanase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="UROCANATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216:SF3">
        <property type="entry name" value="UROCANATE HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urocanase C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="150" mass="16248" checksum="16179B2A5205ADB4" modified="2019-05-08" version="1">MTWIREAGRHQMVVGSQARILYSDQVGRVRLAQAFNEAVRTHRLKGPVVISRDHHDVSGTDSPFRETSNVYDGSAFCADMAVQNFIGDAFRGATWVALHNGGGVGWGEVVNGGFGLVLDGTEDAHYKATLTLNWDVSNGGSRNGQESLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZA6</accession>
    <name>A0A423SZA6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ovarian peritrophin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012161</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002542">
        <property type="protein sequence ID" value="ROT69626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZA6"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="245"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="42719" checksum="2009150D867B48EC" modified="2019-05-08" version="1">MNEAFHTAPASPLDVTPASTAERQGVPRRQFLGSAATERGGHLGSFLFPLLLERIRITMGFTAASTNELICTGEGRFLYPGSCGTYMDCTPSGDGGYTLVKDNCRGYTFDAARKTCIAKPCESRLKRSVTTINHQYSHLCEGQPDKFICGSCRTLVMCVKGQAFIRHCIPNNFCSTRKKFGGGVCYPEEPVECTCTKANDFMVDHYDPQRFFSCEDIGSIPESYKCPDGMEFDESTAQCRNIGGLPPCSVSGQFANPSNCSEYYSCIALKYGWLQKAFQCSKGLMYNKKTQKCEDPCKYQFVCTQEGRYPDYLNKCNYYECIMLGGNMRQERYQCPKGYKWSEVSPGIGKCVEDDGETDEYPFSHCKLDTLCSLRWLPIAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1J4</accession>
    <name>A0A423T1J4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002430">
        <property type="protein sequence ID" value="ROT70419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1J4"/>
    <dbReference type="OrthoDB" id="6381549at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="538" mass="54769" checksum="FDD5923D1D642738" modified="2019-05-08" version="1">MLNQSRPKGSRESSGSGLNRRGREFRGAGRVTRRVSAGFRFVSRDHFHELDSLADLAGSLADYFVGSLAHLAGSLAHLAGSLALGRFLGPLGQGPLQALGHLAGSLADLAVRPTTCLADYFLGYLAGSLPLRLLGRFSLRLRFLYFLAALGRFLATWPGSLAPLAGSLADLAGSLADYLAGSLADYFLGSLATWQVSLADSSGFLADYFLGSWPDLAGSLAATASLADLASSLARLDRFLGPLAGSLADLAGSLADYFLGSLADLAGSLADLQVLGYLAGSLAHLTGSLADLAGSLVDLAGSLADLAGSLADYVLGSLTELTGSLADYFLGSLADLAGSLADLGGSLADYFLGSLADLAGSLADYFLGSLADLAGSLAELTGSLADYFLGSLADLAGSLADLAGSLADLVGSLADYFVDSLADYFLGSLTDLAGSLADYRFLGPLGRFLGRLGKFLGLADSLAELTGSLADLASSLVDLADSFLAGSLADLAGSLADYFLGYLAGSLADYVLGSLADYFLGSLADLAGSLADYLPTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1P1</accession>
    <name>A0A423T1P1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002421">
        <property type="protein sequence ID" value="ROT70459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1P1"/>
    <dbReference type="STRING" id="6689.A0A423T1P1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="981"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1010"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="425"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="769"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="852"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="903"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1035" mass="106208" checksum="ADC0633BDA2406A9" modified="2019-05-08" version="1">MSSQRARLFAAKIRFEIALDLDPEGSSKRTALHRRGRTCTSREDTHPEGRATYAGTCRIFAEADNLFHFSVFIMELVHHAAFRSFAGECFFLNTFLHTAKTSRKRPLFPVSEPAIGWADVTRLLDRWAMRGVGGTRGRGSQRASKELKESEFTGQDFRPQDARVSLDVLLAEPGNSLRMEATPVLVPGPASRRIVGLVQMPLEGSRGDWWEEGEAAEGSGVLGRGKRDYSLEDFFLWMASGDGPSEEWQHRPRDTSWFHEITTTTVFLTTTVYTTVIPSPFTPSTILPTMASSEHINPTKLYEGSASQGVSSNIGPQKGEGKDLGEDGQGGATKNGSDVHERPQSDYPQSGHSGNQIPGSSSSKEQSYDKGGKTNYITVTKTITSPPTLFSTKPSTTSPPSPPDESSYDATDLVRPSIEYPGPSATLTVPSATPSLSQTVTPSLTVNTKPPTGETFYTQPTSIVSFDDSSPTATLDGGSGGDWTDWGELTPEMSQPEPATTAKDVPGTEFTAIMPTPSMGESDENTVEEPSAEHTTETSHEGSGTHETSSGDAATSTDDVAVTTVSEETATTEDDRSPTEITGPVDETLSGGTVVDAIVTEETQGSAEGPLEVTTESSESEKDISVIDAFEPTTALPSAVPTQSATLRPLVEDTGITLDLTTPAGEGTNPDTEDGVDNILTTPSLHDKDDDVPTTPRPDEDPADTTAGVPGTGSTSASAPWYPVTTGSVEAVDPSPVELDEEGGEVATNATNWSESFPETAITLPSEGTAGTESPSASETSTALVGTDGAGGGNGSAGYDADGGTEGNAGDGDGTDVETAAGNGTSIGIEEIEGSAVGSGDGGSVDEHVTGVGSGDGDGSGVGGAHGNDAGVGSGESDGTVVASGDGDGFGEGGSRGNNSVASGGGTVAGSGDGGNGGGSGGGEGPFEGSGDGTFVGSDGDVTTVGSAEDDDTVVGSGDDTIAGSSDDTIVGSGDDTVDGLAVVMLLLAVVMALLLAVVMTLLLAVVMTLLLAVVMTLLLAVVMTLLLAVVMKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2K2</accession>
    <name>A0A423T2K2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002418">
        <property type="protein sequence ID" value="ROT70488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2K2"/>
    <dbReference type="OrthoDB" id="6343044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018992181" description="Condensation domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="58958" checksum="762041BEB40A2C63" modified="2019-05-08" version="1">MCLCVLLGVAWHVIFPSPHPPPTPAPPLPNDPPATPSLAPSCPLPATAPCHPSATPILLTFVRYAITRRESIMDNEIKWLWRTTQTEDFYATYTISYQLTLATREPLLEDHLRQALTHLFRKVPLLRVCFGKRDGEMWIREMAEEALDFEVVSNVPREDIRESLQAYRYDLMKGPLWCVKLLSEPPSSPVVPEGVDMTKFCHVYTLFLGLHHGITDGNSNMRICGFLVQILEAVLGRKDIDDAEQLGVYVSDERTQQLQKEYVASLEADPELRSKVVDEIQSRYGKYSLIKSTFKGVGEKVAKTGVLEMDLDADSTIAFIKRCRAEGVTVNSAFIAATSVSVVDLLVDGGLEQDTYDIRSDHVLNARRYWAGDTSQYLGCHLLPLMPVVAKTPRNITGKFWDFARSVHQELQKKFNEGGPLLEEAGRHFMSANTDFDPTFQYEFCLTNMGNVTNLVTEGGDNLQALHVIRTVAMNTVPCTWSILLHTFRSRLILALTYNTSFVNSEMARKFCDGIFYRIREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T386</accession>
    <name>A0A423T386_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002364">
        <property type="protein sequence ID" value="ROT70969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T386"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="44746" checksum="17EB5CA99E93EEAD" modified="2019-05-08" version="1">MLLDERCQLFPISAETKELLLEGSSQAATARAILSESNQLLTDAVMYNTRDTPVEKAVDRVLLLPYLVKQGRDFDDVDRTLPVAITNCSSLMLSLLDSQSMSRSPFLGGLMGHVTDTTSVFKNIERFERLSGRLGDVASMLHHQNCNCPFKFHHCSDRTEEENLMPSFIHFEDEIDKCEISKTPYQVHVLMAIKNYVANISRIDPSVGGPSVIRRLREWSDMGAGTRYIGSFIADRKTVQDSPFRVAGSNLDVIVRPAAARDASTNILKTLARANASLDDISTTVGLLPELLTAIALFFNKNVSEIISDMVSKSSSAYTIDPATGDVTVDGGRLPVLNNTQHDSRTTTTAATTNSSGDRIRGPAPWQDMAKIHVRNILNQLISNPLSHIMVQGDPIGNVGIETVERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4P2</accession>
    <name>A0A423T4P2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002291">
        <property type="protein sequence ID" value="ROT71479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4P2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="60672" checksum="7203EAE02A5A904D" modified="2019-05-08" version="1">MENGGGGRGKSYFSRNSFPENLETFAPLPLPPPPLSLPVPFPLPPSPLSPPPLPPSPLPLPPFPLFPSPSSPPRTYIFLFPCFSSSLFFPSFLFLLPFFLPFFLSFLPFLSFLLPFLPPPFSLFLPSSSPSSPSFLPSSLLPSSTFPSSPSLPSFPFLPSFFFFFLPSPLPSSFFPSIHSLAIEPNVDLQSIDLGLKAFFSPLLFHSPFSFVSPILFPLLFPLSSLSSSLPFPFLLSLSPSLSFPFSHLFTLHTLLHPKSKRSEGISLSSSLPISPLSLLSPSLPFPFLLSLSSSLSFPFLLCSPFILSFLQNRRDLKVFFSLLLFHSPFSFLLSLSYSLPITLSSLLSLLFSFIPLSPLFPLHTLLPPKSKRSEGISLSSPLSFPFLLSPICLLFSSYYSFLSPLSPLLFHSPFSFVSPVLFPLLFPLSSLSFSLSFPFLLCSPFILSFLRNRSLKPALSALPPISISSSSLLSLPPPLLVAPPPFSFPLLPRSASSLLPLSPLNPFPSLLFLPSSLLLNRPLPSLSPLSCLSLFELSSLSLCSLFHRRFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6K2</accession>
    <name>A0A423T6K2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_009752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the potassium channel KCNE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6K2"/>
    <dbReference type="OrthoDB" id="6362936at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000369">
        <property type="entry name" value="K_chnl_KCNE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02060">
        <property type="entry name" value="ISK_Channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="218"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT71868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="29892" checksum="6EC6CE11A897F7B6" modified="2019-05-08" version="1">MESYVQFTSLWPLCLRTESRHELCERGKHKERKVYIFGEKVDIELVVVPVPAHRDGKPLERAVRSPFVRVAIRCAPGLRLLSCSGLRNLPFNMHSANGTVQFLPEDFALLRNLIEEVIENRCKNDTSAVIKELRSLLQRENATSTEVEESSSEDSLAVVYIVFVLMFFAASLLVIIIKYLRRERESSRLQQFYEDYLQNKYPSLVVHYDETGRRLHPQQSFDSTRYSSPPPTPLVSPVTTPSVTPIATPMLTPTDSPLESPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T754</accession>
    <name>A0A423T754_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_009351</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002184">
        <property type="protein sequence ID" value="ROT72279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T754"/>
    <dbReference type="STRING" id="6689.A0A423T754"/>
    <dbReference type="OrthoDB" id="6364239at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001508">
        <property type="entry name" value="Iono_Glu_rcpt_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00177">
        <property type="entry name" value="NMDARECEPTOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="12">
        <location>
            <begin position="2"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with the cone snail toxin Con-ikot-ikot" evidence="9">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="143"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601508-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT72279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="28637" checksum="DD8732F3945CF3FE" modified="2019-05-08" version="1">MWSSAYLTLAFLLGQSVPRLPSASATRIMGGLWLLSALIISSVYRSNLKAMLILPILRLPFDSMEELVETNILTYVTEGTMLQKQMMDAPPNSLLGRLRSQSVSYWDVPRAIRELMLGRHATFVGRIVSHSVIHRIFEQTNSCPLYTAKKAFWGGTSVAFAFRKDFPLKLKIDKALRRLLEFGIPEHLYRKQVKNVRKCQKDDFTRPSDALRPLDLGDFYGVFTVYAGGILLSLLVFLTEILLGRRARRTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7Q5</accession>
    <name>A0A423T7Q5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mesoderm induction early response protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002142">
        <property type="protein sequence ID" value="ROT72496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7Q5"/>
    <dbReference type="STRING" id="6689.A0A423T7Q5"/>
    <dbReference type="OrthoDB" id="5916873at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042826">
        <property type="term" value="F:histone deacetylase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11661">
        <property type="entry name" value="SANT_MTA3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000025">
        <property type="entry name" value="Mesoderm induction early response 1, transcriptional regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040138">
        <property type="entry name" value="MIER/MTA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10865:SF28">
        <property type="entry name" value="ELM2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10865">
        <property type="entry name" value="METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01448">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01189">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ELM2" evidence="7">
        <location>
            <begin position="163"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="272"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="346" mass="39307" checksum="7567E01A5EE85148" modified="2019-05-08" version="1">MPIEQLLAMYGGYPPEEGEGVEAETEEQANGEGEAIQAENENENSNEVEIENVVEAENEVEEQEEPEVISSRSSTSEENVNNHDKEVKPEVKPERKRREKTSELAQLYADMDTNGDTPTTSSSRSLRCHKPVGILSTVGSRQQSEDEEEEEGEYSGEEEDWHKTIMIGASYQAQVPEGLQAYGATPPYENEDKLLWEPGKLSPKQVHDGEQLVEEYLRALSHPPPGSQGVAAIPLGKHVRDDEQALYLLLQCGYNVEEALRRHRMNPTPLASTMTLWSEEECRNFENGLKTYGKDFHLIQQNKVRTRSVGELVQFYYLWKKTERHDLFATKTRIEKKKYIVHPGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T979</accession>
    <name>A0A423T979_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002080">
        <property type="protein sequence ID" value="ROT72999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T979"/>
    <dbReference type="OrthoDB" id="6361748at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018965742" evidence="1">
        <location>
            <begin position="24"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="22270" checksum="304EE282F6BC0ADD" modified="2019-05-08" version="1">MTSVIFVLHLTLVFFLSVKGCTANGVWDDKGRPALQGFDVYIREDPGDLGGPHGTQDPRHGDRGFDGTSTIHDLASGIVRRFFTDAGSLRQARDISLLSERLADILLLLASDLRLSRSKRHGQTKEDRGSSFEARNRSFSAQSVAEPRFAFFPSLDAWLDELQSTFKRDMIFNVAKVGGIAFLYYFAPGVLTWIESTFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCQ5</accession>
    <name>A0A423TCQ5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007283</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001922">
        <property type="protein sequence ID" value="ROT74212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCQ5"/>
    <dbReference type="OrthoDB" id="6723674at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026095">
        <property type="entry name" value="Myb/SANT-like_DNA-bd_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22666">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22666:SF3">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="2">
        <location>
            <begin position="38"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="22223" checksum="4BC0FC1C3AA20D36" modified="2019-05-08" version="1">MAAFQTGDIAAFQTIEVSSDENGAFVLAAEEDDRRDTEFNNDATILLIKFIRRRYNELQYQRTRPQVYRDVYEELCKHGYNFSVERIRRKWNNLLGSYKRVKKLKKTRKLQWEYYQILNDFLPPEFGEEGTDSYSRYMPESPSYTIRDSYTPSSSSQNFPSSVTVHVPPPSIGKEIERGTKRQAMMEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCS8</accession>
    <name>A0A423TCS8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rho-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007202</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001913">
        <property type="protein sequence ID" value="ROT74300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCS8"/>
    <dbReference type="STRING" id="6689.A0A423TCS8"/>
    <dbReference type="OrthoDB" id="9994905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050770">
        <property type="term" value="P:regulation of axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008361">
        <property type="term" value="P:regulation of cell size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051978">
        <property type="entry name" value="Rho-GAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46005">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46005:SF4">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="598"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="799" mass="90431" checksum="D25A7C4F2C0D9B1A" modified="2019-05-08" version="1">METHGISVEGHLVALSHTFKICSDVLFLMEILSAEEVKHILVRRKSQLTWHQQLDITSKYMVTHLKPDVLYKGKHNIPIFHATRKSELIFIETDEVPKLRNMCNDQSLISYKGTVTSVLDEDIGIYQLDGRTQLVISYIHDITGEIWNMSEDSKDQELFSNRSSEKEKYKFLKAGDKIMIFHAHFAKFDGTPSLTCCGRSLVLKERQSLVSPVGNRSPNATLDMLHYYNFGIHGLKWLAEVRDHLVSVLCPGIVERKHILRRKHNGERSILTQLLRLAADRQLISANPRSLTLEFLSLTHQCVLDKDFEAPFTLLSVLELESSANMNECDNEEKQKVWSYNIDHHEPSRAVIGMLQLGQNGVLQLRDQHADIDLVVVGNKEDLLEKAAPDLSSFLPSIHNPRRRYLKDILGQPASSFQTFATIGRVCKVSFCCVCNFCNAEMVGSSCTYVGCHAQGSGKVVASAQVVIDDGTGTAMVFISSVEHVKVLLQLTPHQYSLLSQEIVSSSHSLSYTSRFKDTDADVAPGKLEGDHMYRVIPEDDSSLEVSSPRDQQSPILPPGAPQRKETDKTARRKQEKLRSREEARQREEERKRAKDEEKLKKAAEKEKEREKKKAAKGSSKSAAKGPPQPTLEDFVQNAVTLPGEVHVEQLTTKFKEDSSVNFAELDIPVNAYSSEGLQQLPPLLPQNQLLELTTIASIGDRSLRLLRLKEMLTGLPSVNFEVLKFIFQHFVRVAENCKLNSMDSKNLAICWWPTLLHTLQFTDISEFESQRPHIEDIIQTMIDQFPFLFQGKEDYVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDK2</accession>
    <name>A0A423TDK2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative histone H1C-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001877">
        <property type="protein sequence ID" value="ROT74560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDK2"/>
    <dbReference type="STRING" id="6689.A0A423TDK2"/>
    <dbReference type="OrthoDB" id="10069608at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF36">
        <property type="entry name" value="HISTONE 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="7">
        <location>
            <begin position="61"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT74560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21480" checksum="CC096ACC33AA30F5" modified="2019-05-08" version="1">MTLVPKTPKTPSTPRTAKSLRIPRSTLKTPRSLKAPRTLRTPRRLKASGRCSAKTPRANAKPLTIGDMVFEAVEALNDRRGVSLHSIKKYLRDNKKVDTEAKALSIKNHLKAFVEEGKLVQLAGTGANGTFKIPGKKTTSQKASACSRVVTKVASRPKIGKLPSSIKDRQSFKNATNMHQKVSKKALKGKMGMKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEB0</accession>
    <name>A0A423TEB0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peroxiredoxin-5</fullName>
            <ecNumber evidence="9">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_006671</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001843">
        <property type="protein sequence ID" value="ROT74809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEB0"/>
    <dbReference type="SMR" id="A0A423TEB0"/>
    <dbReference type="STRING" id="6689.A0A423TEB0"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="34"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT74809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="19985" checksum="60395217673298E1" modified="2019-05-08" version="1">MATLVSLHLRPVLSRAGTATLSQLHKTIVRAMSIKVGDEIPSVDLFEETPANSVNSRDLCAGKKVLIFAVPGAFTPGCSKTHLPGYVNNADAIKAKGIGEIVCVAVNDPFVMSAWGQNQGTGEKVRMLADTNGDFTKALGLEQDLAVLGGLRSKRYSMVVEDGKITQLNVEPDGKGLSCSLADNTMAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEP0</accession>
    <name>A0A423TEP0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006561</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001832">
        <property type="protein sequence ID" value="ROT74928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEP0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="192" mass="20953" checksum="CED7BA70F7F0EE3F" modified="2019-05-08" version="1">MSCDCGDVETEVAPIIVGVLLGVINVSFWFWAIRRTIVKHKEKMKRLSYSTAINNEEMSAPYPLSPVQSSDQTVAATASFASRTAGTPIREDRGTSTPYPIYPPTAPNYPVNLELDNPPSYEEVMSTPQHKPKPSSLQNDPDPPPYISLSSGTRQSSSPSHSPSSTPYPNSPTAPPYPISPQVQLRDDPSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGI5</accession>
    <name>A0A423TGI5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ciliogenesis and planar polarity effector 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">REM2- and Rab-like small GTPase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_005889</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001757">
        <property type="protein sequence ID" value="ROT75572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGI5"/>
    <dbReference type="STRING" id="6689.A0A423TGI5"/>
    <dbReference type="OrthoDB" id="10266641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039677">
        <property type="entry name" value="RSG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14983">
        <property type="entry name" value="CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14983:SF1">
        <property type="entry name" value="CILIOGENESIS AND PLANAR POLARITY EFFECTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT75572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25649" checksum="8DE859BB5A0B75C4" modified="2019-05-08" version="1">MAPEWAIGENKNYQQKLLVPGTKKRKLFGLLEKPNLPPAAPNVTYKLFMFGKASSGKTWTMNRLSGQELPTHHTETVGIQCSNVYWPMKIGNRLILFRLEIWDAGESSVKRYNHVLPACREGVDAVLLCFSVTDREGWLELPRLLTTATTPTDRAALIVIATRCDQYANREVSEGELDSFEATHGVPIIKLGGASEDQSDEITHTAPILNFLCKRLWQRDQELLSIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH30</accession>
    <name>A0A423TH30_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001737">
        <property type="protein sequence ID" value="ROT75759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH30"/>
    <dbReference type="OrthoDB" id="10006218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="28507" checksum="8F80DFAE1B8E9761" modified="2019-05-08" version="1">MVPFGGTYCKGYLDNEKYVCLDDDVKPNSRNCTVYSFGVGADTTFDDMASYYGCDIFMFDPTINGSELQMTNSEREAFYPWGLSSFHYKQNFSIEYDGKPTEKLEGEFTTYEDIRKRLGHQKRDVNYLKLDIENMEWSVLPQLVKGGHLDRVSQLAIEVHTMDIIKASPEKVLPLLQSYWQILVSLKQLGFLRVSHRFNPVLETIYFDRAHNQSISTCMEILYVKRGFNRRRHLQSRLPLPEVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIL3</accession>
    <name>A0A423TIL3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001676">
        <property type="protein sequence ID" value="ROT76290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIL3"/>
    <dbReference type="OrthoDB" id="6347053at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="623" mass="68936" checksum="8EED72F72865D06E" modified="2019-05-08" version="1">MRIRLEFVADKFVVNAAPATSAHNPVAYSAFREEKNNPPRIPSSGLECFGWAVTEANVPVMFVATQEEKLSSAANALCGSKGVSVTFAADPDAQIRSGSPSDEDVKETNVAYKATRLLRTWHLASTLARPTATRVPASSTLSRQTGVMARGVAGGVAEERNETIKWLWEADASEVMLAVGHAHGCRRVLPCYTLNTLAPLRPEQVEEALRHLQRQTQALRVFMKIRNGKFWICESDQDEISFKVLEGGDPVQAMWRYTNTPVGYDQAPLWQGVFMPGNGSDARAASGPSHLKEVRERFPHQSYLAMPIHHAFIGGPTMPLITQRLVELLNAVIAGRPIDDSRQVGELVPSTEIDAAKRRIREEFERDPARLEAMKEEMLACDSEPVLLKAFPRPGGAPSSGHVFRDVSPALLQKFTAKCKSEGVTFNSGLQGAINTALVETVAEAGLQQDAFSLSINLATDVRRYMSRNPLEVLGLHVRPTVHRVATPARVRDHFWHYCRALHALRPIRSGLALQQEVVREMTQPPGDPHRYYMTPPPVLRDFGLASVGDLTTLIRGEGDHLQLTDILMASSAHRFLYMMLHQIYTFRGHCPYSVSYDTSYMTHETATLIADKVLATIADICK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TK84</accession>
    <name>A0A423TK84_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_004538</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001600">
        <property type="protein sequence ID" value="ROT76864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TK84"/>
    <dbReference type="STRING" id="6689.A0A423TK84"/>
    <dbReference type="OrthoDB" id="302966at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000062">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045103">
        <property type="entry name" value="RNF5/RNF185-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12313">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT76864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="160" mass="17043" checksum="C6A2725C15D0FA85" modified="2019-05-08" version="1" fragment="single">MATAGPGSDSRSESSNNASGGSDKGGEDSTDNSNFECNICLDAAKDAVISMCGHLFCWPCLHQWLETRPNNQTCPVCNAAISREKVIPLYGRGSGNQQDPRDKLPPRPPGQRTEPEPQNGYMPGFGFGGGRGFQFHFGIGAFPFGIFTTFNNWGGGAVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKH1</accession>
    <name>A0A423TKH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cuticular protein CPR76a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001595">
        <property type="protein sequence ID" value="ROT76907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKH1"/>
    <dbReference type="OrthoDB" id="6427684at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF79">
        <property type="entry name" value="CUTICULAR PROTEIN 50CB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019065438" evidence="4">
        <location>
            <begin position="19"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="150" mass="15850" checksum="32479F0DF67CECB4" modified="2019-05-08" version="1">MACKQLLILSVLVAAITAAPQFSIEDETPVPHDFAYGVEVSDTGDAKEHKQTVSPSGRTEGEYRWLQPNGLYTVVRYYVDGDSGFQAEVSEEPGPAVGNYYTNSLSQESSSGAASASSSQSFARSFDSQQSSLGRNVNVISAPGPPSAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TL62</accession>
    <name>A0A423TL62_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001562">
        <property type="protein sequence ID" value="ROT77179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TL62"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="45262" checksum="7B59532E42F6AF43" modified="2019-05-08" version="1">MTGREEFTEAGRGGWLLIVKFLSPVSVWCLFCLLLSLLLSPSPLSSSLPPSPSPLSSLALSPPPLLSLQPALSPLLSSLFFISLLPLSLNPKVSLAPPPQKKKPEKSASRPRAASGSRVAFFCPRKKNISFRRPPGPPNFQFSFLSPPSPSPKVKKPLLFFLSPLFYPYKQTPSLFFFPFFSSLPLLFSLRSSKASGSHLLFKNQPFAASRSSSSLTKMIGFELGTRRVSLTPPAITRRRELTVSPNDMHPVLNVSPPRVAFGYTGRGPRRSPGESCIAFLAATIDQINVTLLWVSLFFWATHTPRLPPSRSSSQDVYLTPLPSPYPLLRDSFSPSGDLYSGFFFPQHDSFALFISYLVYLLLAPLSLSNNPPPPDLLPQRLVPFSSPLLSPSPLPPVLPPPLPIPLLPFPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMN5</accession>
    <name>A0A423TMN5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001493">
        <property type="protein sequence ID" value="ROT77697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMN5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="44969" checksum="A1D30621B9C0F81B" modified="2019-05-08" version="1">MPRRPSQSPDVPLEAQTSLSKPRRPSQSPDVPLEAQTSLSKTTKQTSLSQAQKAHRPLRPRTCPLQARTSISSSSKAQTSLLQVLSEVASQIRPSSQNPDVLSIPSLSSPDVLLKPRRPSQAQDVPPQARQQTCPSSKAQTSLSKPDVSLEARRSSSKPRRPLEPQTSFFEAQTSPRPQKSAPRRPLRAQTSLSKPRRPPQSRPFSLEAQTSLSKTQTSLDVPLKAQTSFRSADVPSQSPDVPLKAQTSPLKPDVLSKPEVPLKPRHVLSKPQTSLRPLSPANPPDVPLKAQTSLSKPRRPSPALPARPLKARTSLSSPDVPLKPRRPSQSQTSLSKPDVPLKAQTSLSKPRRLSRSPDVPLEAQTSLSKPRRPSQSPDVPLKAQTLDVSKPRRPSQSPDQSLNVSLEAQTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMV1</accession>
    <name>A0A423TMV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pigment dispersing hormone II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003563</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arthropod PDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001483">
        <property type="protein sequence ID" value="ROT77756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMV1"/>
    <dbReference type="OrthoDB" id="6378554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009396">
        <property type="entry name" value="Pigment_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06324">
        <property type="entry name" value="Pigment_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0027">Amidation</keyword>
    <keyword evidence="4" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-0529">Neurotransmitter</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="14914" checksum="BD4E13AEC8C707D4" modified="2019-05-08" version="1">MLITTSKATCLPSLAPARTQPESRGRSASRGRDRVGALRSHIKGPGAPGGIAFFFSCPLCKMCRFAMLLFVVLAVTAVVVTEAQREPSASKCQAATELAIEILQAAKGAHTGVVVGPHKRNSELINSLLGLPKFMIDAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNM3</accession>
    <name>A0A423TNM3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mucin-2-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003273</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001446">
        <property type="protein sequence ID" value="ROT78032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNM3"/>
    <dbReference type="STRING" id="6689.A0A423TNM3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019280421" description="Mucin-2-like" evidence="2">
        <location>
            <begin position="30"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="744" mass="79571" checksum="4DF3D4870A481C60" modified="2019-05-08" version="1">MAAPKPPSSGSMLLLACLLACAAKGAATAAQDLSTLRQVAASLDHADAALANLTDLLREVFYSNASTTTPRLQQNLQPLRLQYRNIPSPPTTETTTPSNRNYNPFVSNNRNYNPFASNNRNYNPFKLQQQKLNLFASKQQNPRLNNRNYNPRLTDTSNRNYNPFASNNRNYNPFASNNRNYNPFPSNRNYNPFASNNRNYNPFASNRNSTLRLPTETTTPSPQQPNPTETTTPSLPTETTTLSPPTETTTSSPPTTETTIPSSPTTEITTPSPPTTTTTSSPPTSATSTTSTKTTTMTTLTTTTTTNTTSATITTLVTTATNSTITTTPTTATNPVTSPTTIVVDTTNATTPDTTPLTTPTIPTPTTTTTPTAITPTATTNPTTTNPTTNTTTTITTPTTTSTPTTTTPKMTTTPTAITTPTTIPTPTTTTTTTTTTPTTTTTQPPTTTKSYDHNSYNNHYNHNYNYNSYNDTRQRPNFYNEHNNVLQRPQLLQTTTTLQQLLSTTDPTPTTTTTSTTTTTPTTTTTPTTTTTPTTTTTQRLTQLLTTDLQTMTTTYNDHNSYNDQLLRPQLPREGRRPTRAVPRVRGEVAGGAADATHASQLDGEASRLDRLVAEGRGDPALVLEAGEEEASRLMEDLEEVAREVAGAGDVVQQEIDRAQVGAVGGAASLATGPRESRAKEGGAAAAAAGNGRGRRQREAANCAWISKVSKAICPRAGALRGCEGAALRSPPTEATAAGLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPX2</accession>
    <name>A0A423TPX2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001372">
        <property type="protein sequence ID" value="ROT78495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPX2"/>
    <dbReference type="OrthoDB" id="406773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019429276" description="Methyltransferase type 11 domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="292" mass="32951" checksum="3AA7704EB3469E54" modified="2019-05-08" version="1">MPAFIMCNSSRLLLVCLVAFGFMMMHSQIQGIKERVQKGDTEDKTSVLESSMNKNSQLIKNIYCAVADVQPSGGYCLSDRHILTGHNEAWDGKLCKALEELFGYSSVGDFGAGLGHYGRCFLRHDGDFIVRGNEIERNALTRFFWQEMTKAKLAQTPQVIQSWHGYDGGSNIEKMSGGKIQQLELGAPVNLGRRFDWVMSIEVGEHIPVESEDIFMDNVIRHACKGVVLSWALPGPTGHHHINNRPNDYIIGKMKKKGMIHDLQAQTHIRTEIVAHWMKDTIMVFRFPKARC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQ83</accession>
    <name>A0A423TQ83_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001356">
        <property type="protein sequence ID" value="ROT78604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQ83"/>
    <dbReference type="STRING" id="6689.A0A423TQ83"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="716" mass="80143" checksum="0D57FA0EC92A3E10" modified="2019-05-08" version="1">MEGRLLGGLWLGALCCGWLAVVPVNALLSALAPSAIALPSLHHSTLTLFIRRFPVPSRQTRNKRQPHQSTGTSKPSCWLYEARWVRPFRNEGCCQESRKEGCCKRKKAQRRLFKEGCWQESRKEQEGKEGCWQESRKEGCCKKAAKKAKKGRLLARKPQRNVAKKAAKKAVGKSPKEGFCRKPQKKAVGQKAAKKLLARKRKEACWQESRKEACCQAQEACWPESRKEGCSRKPQEAAARKAAKKAVGQKAAKKPAAKKAAKKPAESAKKPAPRKKKAKKPQSLLPRKPKEGCWQESRKEGCCQKSRKEACCQESRKKACCQESRKEACWCKEKKAKEACCQESPKKPAARKPQRSLLPRKHKEACCRKNKKAAKKPAAKKAAKKPVGKKAAKPVEESRKEACCQESRKEACCQESRKESLCQKSRKKKPAAKKAAKKPAAKKAAKKPVARKPQKKPVGKKAAKSLLRKEAVAKRKKKQEKEACCQEKQEACCQEKAKKPAARKPPKSLLPRKPQKSLLPRKPPRSLLAAAKKAAKKPAARKRQRSLLPKSPQRSLLPRKPQRSLLARKPQETEARKLPRKPQRRLLARKPQRSLLPRKPQKKPAACCQESPQRSLLQEAAKKSYCQESRKEACCQESSKEAVFAKKAAKKALPAKKECKEACCQESCKEACCQERNPRSLLQKAAKKPAAKKAAKEPAAKKAAKACCQRESRKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TS63</accession>
    <name>A0A423TS63_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thrombospondin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_001971</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001260">
        <property type="protein sequence ID" value="ROT79304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TS63"/>
    <dbReference type="OrthoDB" id="14563at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="217" mass="23084" checksum="F12C228C6398DEA1" modified="2019-05-08" version="1">MQHYFECFMESGKMVKQRYQCPSGYMWSEESFGTGKCVEATDEYLGYPFAHCDIPDDLCPETDPCLQNPCYSGVACTFTSVAPFYTCGACPAGFTGDGETCDALQCPVGFAGIGGDCAPDSDLDGFPDTELGCSSKYCRKDNCDNCPLTPNSKQEDADSDGRGSLNAADNCPLMANSNQADADGDGLGDVCDNCPLNPNPGQEDVDEDLLGDACDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTV2</accession>
    <name>A0A423TTV2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001184">
        <property type="protein sequence ID" value="ROT79862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTV2"/>
    <dbReference type="STRING" id="6689.A0A423TTV2"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="483" mass="54353" checksum="853D719835775848" modified="2019-05-08" version="1">MSRHSRPWYTLALLPLPPRPGDLRRGPTRRLAAHLLSRLSPILNPSPPLLSLSLSSLPPSRPVSSALPLLLLSLSLVSLSLLTISLSPRLLHFSFVSSFSKLLTSSKLCPSRPSPSRVPLQLARLSLLPLSLPLHPLSATLVQEKSIQRRRDTLPSHSSKHSLHLEARHFHLLSCQGVGRRRREAKCMCKDSGRAELVCGTELSSCSQLTEILNKQIFPTSHYYKLTVYGTQLDCVIEKDLWGPLDFEKVVLANNQFTSVDNHAFIPFKDRLKTLNLEKNKISNFFFPVISELPNLREFVIRKNELTFIPGHAFFNSSSIRIFKASRNQLDITSDTFSGLPLLEVLDLSYNKITKLSTHVLRIPNHQADWLKIDLSYNEIQKIEPNAFSGIRGCMINLRNNRLITLSETTYRPIIDFTNAMVTFLVSENPLECDCNISWIVHNATVSRCFDNFHCPNLNEGLGTIISSDLGNCTLRKPGPSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUE7</accession>
    <name>A0A423TUE7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Sodium-dependent multivitamin transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_001197</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001158">
        <property type="protein sequence ID" value="ROT80074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUE7"/>
    <dbReference type="STRING" id="6689.A0A423TUE7"/>
    <dbReference type="OrthoDB" id="6352050at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11492">
        <property type="entry name" value="SLC5sbd_NIS-SMVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051163">
        <property type="entry name" value="Sodium:Solute_Symporter_SSF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985:SF40">
        <property type="entry name" value="LD47995P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985">
        <property type="entry name" value="SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="283"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="449"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="514"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT80074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="577" mass="62455" checksum="7B0A54ECD77DD6E4" modified="2019-05-08" version="1">MLESHFNFSEGERGSFSWPDYVVFGGMLVLSLAIGIFYAIRSRKKANDEFLLGSRSLSCFPVSMSLVASYISAILVLGGPAEAYYHSVQWWVICAGQVSVPLAAVVFMPFFYELKLTSVYEYLELRYSSRVVRLVAGGLFILETLLYQAVVIYAPALALASVSNFPLWISMIAVGVIASVYTAIGGLKAVVWTDVFQLIILIAGLFAVVTKGIYDLGGFGVVWDIAERNDRVGIQIFTYGYDLLQRHTVSNLLINEVLMQLALFACTQTTVQRYSSTKSLAHAYLSIFLTIPFFVLLISLTMAAGIVLFATYEGCDPLAAGLITKKDQILPFYVMDRLSSIPGLPGLFLLCSSLSSGVNSQAAVTWEDVFSRRPGCVRLSSTTQARITKLIALGFGFLSTGLAFLAGNFGGLIQAAMALTSGVSGPMLAVFIMAIFLPFTNSKGATAALIIGTAAAFTFSFGSAALGIIPELLPTSTDLCPANITLPPPPDSPPIRASDLEYPEKIFGLSYTQLGPLGFVVALVVGVFVSLLTGRNRGVRVERSLVHKWVRWSLPDPNKVTDRVKANSYSNSISTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW90</accession>
    <name>A0A423TW90_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">C type lectin containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_000542</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001083">
        <property type="protein sequence ID" value="ROT80706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW90"/>
    <dbReference type="OrthoDB" id="664115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019457410" evidence="3">
        <location>
            <begin position="31"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="4">
        <location>
            <begin position="172"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="326" mass="36242" checksum="FD83D7649B128549" modified="2019-05-08" version="1" fragment="single">NRCPYAHARTPIPAPMKRFVLLLCLGFASALDCTGDEIACTSGERCVPYRYLCDSDNDCADGSDESPDLCLAWRNTQCEKGQAQCHANGDDQCISIEAYCHRTQPACDGSLDRRICSIIKNKSLVPLSSIRLPPSNDPGVAYNKSVELGSELRLNLNSTLSHPDCPRFYTRVGGQCLSVFYVGSSSWGEARSFCKHIGGDLLSIQNVNHYVDLVNHLVDNRITSDFWLGGRYEVDDLSWTWLDGTPMPRGTPFWSLRRYDSCNPRNVTLTGTSEVREANNGECYHYTQAPENPPKGFCAAITYDKHFYMSDEDCLADMSPLCVTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYN8</accession>
    <name>A0A423TYN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000951">
        <property type="protein sequence ID" value="ROT81567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYN8"/>
    <dbReference type="OrthoDB" id="8191482at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF224">
        <property type="entry name" value="CUTICULAR PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019084467" evidence="2">
        <location>
            <begin position="18"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="23044" checksum="D31EB25907888695" modified="2019-05-08" version="1">MKWIFVVLGALVGAAWGAPVADEPLFVVVENDPQQSLAIINEEQQRPFVPIEIPEDSNFRYLTRDFEGATYQFGYNTGNTFDEDGVPQANMYRHEMRRQDGTVVGRYGYVDPEGVERVFNYVVDEGGYRLLEAGDILALDVVEEAPQEEEEPDKARLDLPLEEPRTPIAALPVVPEGAADLSSDAGTYGVGPAVVYGVVAFPSREREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZK1</accession>
    <name>A0A423TZK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000907">
        <property type="protein sequence ID" value="ROT81890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZK1"/>
    <dbReference type="OrthoDB" id="6377195at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="333" mass="36524" checksum="E3A3227DB39B2C75" modified="2019-05-08" version="1">MGTANKTDTKKLYFISPSSLPLRPLLPFLSLLSLSTFTNSPYLVPRSTLLLIPHPFLPLPHSYPISILLIPPPFPPSPYSSHISTISLILPLPILLPPFPPFSTIPLPPFPPSPISTIPLIPPFSAFSPFPPSPSPPLRKASLEHKGSIAVAAVYKVRAFLGLAQCLPSLVAPRNARPLSALSAFLKRRSLGSHDDHRHHRSVGRDRWRRRTRRTRRRRSCRGRRSVDDAEDWRMQNALELVRAEDVTGCGMRLVCELAGQEEEDLVQEELAILALLGPDVKPGEGVLPPGGARGEYLQARNFGAQGGDCGAAFPMCPLNGSQLMDTVMAYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1G7</accession>
    <name>A0A423U1G7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000810">
        <property type="protein sequence ID" value="ROT82531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1G7"/>
    <dbReference type="OrthoDB" id="6360870at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019499472" description="WAP domain-containing protein" evidence="1">
        <location>
            <begin position="37"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="42"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="102" mass="11097" checksum="6FC82F6B98D07B8A" modified="2019-05-08" version="1">MLAKESSEPHFTVMSSTAVRVCALLLLVLMLENSWAMGPFPGLQKKGFCPLLLSAPIDSDSLGFERTGCRGDYECEDDLKCCPGGACCHFSCMKPLDRLTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2X7</accession>
    <name>A0A423U2X7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000749">
        <property type="protein sequence ID" value="ROT83034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2X7"/>
    <dbReference type="OrthoDB" id="6349016at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="264" mass="29978" checksum="DCD2A0DE34FD992E" modified="2019-05-08" version="1">MARKRSRRLSRRLHHLQLLYKTNPLLVRRCSPRRLGHISKFYALVRMRSLWRLCERRFLLDTMRYLLSACVAWCLLSLSAGGLVFPFNWLVHSTAPLFNPPAPLPALLGVVPLTGGQILPSIIVSLLAMKGAFIIGYLIYEAADYKDVKEFRFPRSVSDHETLLMSTVSQLDQNNCILKLLCQLQTKTAETRTPQENVIVDLFSYHLDAFAHVANASVFSPVHEVESNALDVGMCDSYFSKCPFAEEHLRALLQYVWSCGPPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5J9</accession>
    <name>A0A423U5J9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RUN domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000610">
        <property type="protein sequence ID" value="ROT83986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5J9"/>
    <dbReference type="STRING" id="6689.A0A423U5J9"/>
    <dbReference type="OrthoDB" id="10068328at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17683">
        <property type="entry name" value="RUN_RUNDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058732">
        <property type="entry name" value="RUNDC1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047343">
        <property type="entry name" value="RUSC1_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15591">
        <property type="entry name" value="RUN AND SH3 DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15591:SF19">
        <property type="entry name" value="RUN DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26030">
        <property type="entry name" value="RUNDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00593">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="3">
        <location>
            <begin position="528"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="719" mass="82492" checksum="BB30FA08A8D27E15" modified="2019-05-08" version="1">MSEEDFRRAFERIVKDEKMVSPTEREICLLKELSLGCRIPVLTCFQAGSSLHFSPFLGMAVHETQQTFNVIEAQKKLFDNALEGNFADFEHKESQDFANFDKMNSKCYEYHNEEKQIEQDFGKEHYISDRKEACGSPCSMSKIGELEIDQKLSFQEHRLGTSRGFRDFKEGLKEEYSDKSFADFKADMKNSFTSSLNQSFGDLETSSNKGCDLGELTSYDVEWDSDGHPTGERWPPLGAPNDDEDNQSLYSYSEYNWQRGQSSRGGARLEDDRLQQLEEEQEQLNTSLLALTSHFAQVQFRLKQIVDASPDEKEKLLHELEEFANRGIPDLREANARRKSTVSEHVDGEEDDHAGMAKQKELIEKLKQQLEDLENYAYQTGEGGPPQAKVMEKQRVVIEQLKGTLNLNVDEFDRLSVDDLKVQVDSAIREVRAPVESSKMVRFLVDAKHLKHVTREMGSHKRVAFLRAGSVHKDAKVRARVRRESRDLRAGLEIAVNNLLDVLGPEVTADSDYTSDSEETPIMISNEEVTHIVRKQLTPALRDLMQHGLMPVGQSQSLVPFLSCFPQRSHKPTKLMHAWDLILKYYQLKKGDQYNRTPARRLSQSFNLDIHGGSAVTNKQNLLGIIGNIISTHTPLKRSYDSHLKAFVCAALNQNKLITWLRLIFRTQYLVENYYQSWSYVCKTGFEDAFRSMERLNKYNFDLPVDLAVRPFQNIKDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U742</accession>
    <name>A0A423U742_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000530">
        <property type="protein sequence ID" value="ROT84543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U742"/>
    <dbReference type="OrthoDB" id="6372445at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="47770" checksum="29109030F1031E45" modified="2019-05-08" version="1">MSTPGTPTTQRKRPFSQANQNGETSDGTGGLLGALGEVVGEWLQGWGLLGALRKRSGAPGVARSTPATPPTHSHPSSPSHEHIELRQLSFQCREGDGGSGEGGSRQLTPCEVVRRRHPLNFPRSPRPPRHSYYEGSSPDSYLLTAVLIHSLKHGSGKVCQEPHCNVCITRFGQNLREACGLDLSMISQKGDHSLDASLPTALYSRSISQEGNEVKNWKHDRKDYLDISTDMQELSQVSPLSSPSSSFPYAQISPLPSPQSSITMSSTLTSRNPTLSLTTCESSAPLLESELSSLDISSLTDVTMSSSMLSNSTLSLQQSECLLASESNITSSELSLITASDCGTLVGSFPSETFPSAACSSETISSETYPCDTYPKCRESGDLMSSSVHSLPSRLTLKDRSSASLLRPVLLSSGSLVLLPRRPSLVSPPSVSSASSQGHFKWEEVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAA6</accession>
    <name>A0A423UAA6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000231">
        <property type="protein sequence ID" value="ROT85615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAA6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="951" mass="104369" checksum="D2978C2EF86EA265" modified="2019-05-08" version="1">MALFPSSWHPFLPQGTLPFLMAPFSFSWHPSLPHGTLFFLMAFFSSSWHLFLPHGTLLFLMALFSSSWHPSLPPGTLPFLLSFSWQPLPLLSWHPSLPHGTFFLMTHFSSSWHPFLPHGTLPFLMAPFLPHGTLPFLIMAPFPSSWDPSLPHGTLPFLMAPFSSSWHPSLPHGTLPLPYDTLLFLMAPFPSSWHLPLPHAPSPSSWHPPLPHGTLPSSWHPSLPHGTSSSCTSLPHGTLPFLMHPPSSWHPSLLMGTLLFLMAPFPSSWHPSLPYDTLLFLMAPFPSSWHLPLPHAPSLLMAPSPSSWHPPLPHGTLPFLMAPSPSSCTLPFLMAPFSSPSHTKASGRGAKTPSLPHGTLLFLMAPFSSHHGTLLFLHGTSSLLLALFFSSWHFSSSLFSSSWHSFSSSWHSSLPHGTLSSPHGTLLFLMATLLFLMAPSFSSLATLLLPHGTLLFLMTLFSSSWYPSLPHSTLPFLMAPSLSSWHPSLPHDTLLFLIAPFPFSWHLPLPHGTLPFLMALFPSFGTLFLPQGTFLSHGTLFFLMAPSPSMAPFFSSWHSSLPHAFSPHGTFLPHGTLLFLMAPFLLMEPFPSSWHPSFLMAPSLPHGTFSFLMAPFPSSWHPSLPYDTLLFLMAPFSSSWHPSPSSWHPSLLMHLPSSWHPSPSHGTLILMAPFPSSWHPSLSSWHPSLPHGTLPSSWHPSLPHGTLAPFPTSFNGHPPPHGTLPLPHAPFPSFMAPSPSPHGTPPFLMAPFPFLIAPMDPPLPHGPFPSSWHPPLPHPWHPSPSSWHPSLPHGTLPFLMAPFSSPSHTKASGRGAKTPLTRLKTQDFPALEGGTLPLPHGTLAPSLMAPSPSSWHPSPSWHPSLSHDTLPFLMAPFPFPTLMAPPLPHGTLPSSWHPFLPYGTLPFLMAPCPFPMAPYHPSPSSCTSPSSWHPPLPLLTAKPQVAVLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSI0</accession>
    <name>A0A3R7LSI0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003471">
        <property type="protein sequence ID" value="ROT63242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSI0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="39939" checksum="2EF473759CFCA6B9" modified="2019-04-10" version="1">MLLAPLSFNFSFLYLLSSLIFPPGSLCLSSSLPASSSLSFLLWFSLSSLFFLLLFLVFSGLLFSSLLLLLLVLSLLYLSSILLSLFVLLLVCSLLRFPSSFLCVLFFAVLYIFFSSSSSFVIPLLLLRVSFFPPSLSALLLLLLHGALPPVSRLLAFSRSSSSLSSSSSLFSFNSSLALPKCMSSLECTCTSALVSADFYLCFSTPLASFPFPPTPSLSSIPPLRSLLSPFLYPPPRSPPTPPPFFSSPTSSSLFSFHLPLLSLFSLHLPHSPLSFPSLSLFPPFSASLALISLIFSLLPHPLLSSPFLSSSLSLSYLPSHPSTASLPPLSSPFLPLSAPPFPPSSSSLPPSPSFSGRARAAHDPASSLSASAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LX76</accession>
    <name>A0A3R7LX76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_020517</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LX76"/>
    <dbReference type="STRING" id="6689.A0A3R7LX76"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000215">
        <property type="entry name" value="Proline--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT61669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="45166" checksum="AA5E35AEF67347AA" modified="2019-04-10" version="1">MAEPIAIRPTSETIMYPAYAKWIKSHRDLPIKLNQWNNVVRWEFKHPQPFIRNREFLWQEGHSAFATKAEAEEEVLKILDIYARVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFVPSSGRGIQGATSHHLGQNFSKMFEITFEDAKTLEKSYVYQNSWGLSTRPIGAMVMIHGDEKGLVLPPRVADVQVVIVPCGINAKMTDEQKNSLFDGCSTIENTLKELSIRAECDLRDNYSPGWKFNHWELKGVPLRVDVGPRDLAKKEVVAVRRDTGEKLTLPLANLADKIKSLLDEIHTSLLSKAKEELESHKKLVHSWEEFTNNLDEKNIMLAPFCGAEACEDVIKKESAQEEVAGAKGPSMGAKSLCIPFEQPADATGKICIHPKCEQPAKFYTLFGRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1T6</accession>
    <name>A0A3R7M1T6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Dscam2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_012359</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1T6"/>
    <dbReference type="STRING" id="6689.A0A3R7M1T6"/>
    <dbReference type="OrthoDB" id="6377417at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000017">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000324">
        <property type="entry name" value="Down syndrome cell adhesion molecule, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:001049">
        <property type="entry name" value="Down syndrome cell adhesion molecule-like protein Dscam2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000005">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="11"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="103"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="195"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="293"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="13">
        <location>
            <begin position="383"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="54758" checksum="B12A908B948C7E18" modified="2019-04-10" version="1">MVNEPRSSVPPRITDSRSSIRASVRDTVELPCAAQGYPIPQYKWHRLSQKEEVPVVQDGRIKQVGGSLLIRQVTAGDAGKYVCVVSSSVGSERTHTTLEVWAPLTAHITPQVQTVDVGSIATFNCSPEGFPQESISWFKDGERLEVTGRVRVEGQRTVVVEDVRREDRGMYQCLVKNFEDTAQGSAQLKLGDASPQWRTTSGPKVVSPGATVMLMCAVQGSPPPAITWTLQGQPIPHNDPRITYSQKVEGDHVEGQLNMTSIRVEDGGDWTCEARNRAGRVEHTGRLDVRGPPTIRPMRPMRVVAGRTAMFNCIVAGYPIESIYWEKNGVVLPVSERQEVHSNGTLEIRQVSREADSGQYICVATSGENTARANLQVNVMVPPHIDERMFSLGSGFPAKSRARIMCVVERGDLPLSFSWTHDGRPLAPGPATSVRSLDEVTSVLLFTSLREEDGGKYTCTATNAVASDSRTVELVVKVIASVIVIIVLSPSFHSSLPTSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5B2</accession>
    <name>A0A3R7M5B2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (carboxymethyluridine(34)-5-O)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.229</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alkylated DNA repair protein alkB homolog 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">S-adenosyl-L-methionine-dependent tRNA methyltransferase ALKBH8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_014343</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-(carboxymethyl)uridine(34) in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:10408"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74851"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.1.1.229"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.229" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002799">
        <property type="protein sequence ID" value="ROT67574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5B2"/>
    <dbReference type="STRING" id="6689.A0A3R7M5B2"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RRM" evidence="16">
        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="17">
        <location>
            <begin position="210"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="508"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT67574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="571" mass="63185" checksum="69E8A1B94D1859F7" modified="2019-04-10" version="1">MSGKRDKAQKKIARCLAILQRDLPDIQPSETPTKFLFIGNAGLTTNADESSLVELITRTGTSLEAIMLIPGKQYSFACFASEDQAKQAFESAHGQMDSPGASSPVYMAYVDKVPPKPAEQLTPPPGLQIVENFISEDEENMLMNLIDWGEKPGDKAEGSLLKHRQVRHFGYEFKYGSNSVDKDNPLPFGIPEALNGIVRRIVEQGWMPVPPDQLTVNRYLPGQGIPPHVDTHRSFTDEILSLSTGGGVIMDFRLGVSEKQQHHTMYLPSRSLCVMAGPARYEWTHGICPRMTDVVSGKNGIAGLHLCPRQERISFTFRKVREGECNCGNRRVCDSAIQNSGYDPNKGAASSDSISDDIQAMRLEQQHVLQVYDQIAGHFSATRYKPWPNVLEFVNSLPLGAALLDVGCGNGKYLGHNEKIFQMGCDTSYELVKICNTRGFEVLTSNCLQLPFRDSTFDAVICIAVIHHLASEERRLASLKEMARVLRIGGQGLVYVWAMEQQRGKKKSAYLKQNKANRKDEGHGEYVGANATSDMDTESGKSDSFSSGLKKELIDASSSFTSSKWVKSHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5J6</accession>
    <name>A0A3R7M5J6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5J6"/>
    <dbReference type="OrthoDB" id="10289826at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="14746" checksum="E9B01634585F0EDE" modified="2019-04-10" version="1">MCAQLQRQRGVSEEGRGLRNMHRESNRRERMVQTIINCAQQLDIKTLPSFDSSQDPSESSYMRFRVWMRAHPEDKRRLFACAHQGLFTPDGHAEPHGAGRRVLAVLETRSANFEPPSSTTSKHARRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6Q5</accession>
    <name>A0A3R7M6Q5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gamma-glutamyltranspeptidase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013229</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002652">
        <property type="protein sequence ID" value="ROT68616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6Q5"/>
    <dbReference type="STRING" id="6689.A0A3R7M6Q5"/>
    <dbReference type="OrthoDB" id="1081007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.130:FF:000001">
        <property type="entry name" value="Gamma-glutamyltransferase 5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.40:FF:000001">
        <property type="entry name" value="Gamma-glutamyltranspeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686">
        <property type="entry name" value="GAMMA GLUTAMYL TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11686:SF9">
        <property type="entry name" value="RE13973P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01019">
        <property type="entry name" value="G_glu_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01210">
        <property type="entry name" value="GGTRANSPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1199">Hemostasis impairing toxin</keyword>
    <keyword evidence="1" id="KW-1202">Platelet aggregation activating toxin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0800">Toxin</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="342"/>
            <end position="344"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="392"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00084097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600101-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT68616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="511" mass="55961" checksum="F97C350F943508EA" modified="2019-04-10" version="1">MAHSSRSAVAGLFCVGVINTQSMGLGGGFLMTYYDRSTGKAYSLMQGKCAVRSLRGHVWRGRGISSERRACCGCPWRTPRIPELYERFGGNLPWAELLEPTIKLCEDGHLVNWHMARALKFNAEDIKKEPSMSVFINPETGDVYKEGDTLKRPQLAKTLRDLQQDPDALYSGQLASKLAQDIQSFGGIVTEEDLRMYKLACVEGSHEHYTAAWPDKYVLCASPGSGLILGFILNILDEYGLTPESIDDSNIVLTHHRITEAMKWAYAKRTELGDADFVDMSGLTKNLTSDDYAAYIHSQITDDRTFQDPEHYGAVTADPDDHGTAHFSLLAPNGDAVSVTSTVNLYFGAGIRSVQTGIVLNDEMDDFSAQTSQITLGFLLHLPTLLGQRPLSSMCPAVFVDSKGDVRLIIGAAGGTKISSGVAWASLRNLWFGDNIKEAVDARRIHHQLFPMTFSYEQGILPKIVEGLQTIGHVTEEFGIGGSVVCAIARGDNGKIYANSDFRKAGEVDGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-05-03" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M839</accession>
    <name>A0A3R7M839_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001870">
        <property type="protein sequence ID" value="ROT74630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M839"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="211" mass="22269" checksum="0ACEE7F5AF8FF83E" modified="2019-04-10" version="1">MFPCWSCAGPHKLTCSQTGVQPQTPDAPVYPRSAPSPRCLRAPWSGPDPAPPLPTLKHLASSSLLPAVEGGEAITFRYRHCKESAKCGNRGGTCVKADECDDQGAKRRGCGKGCVCCNEDSKPVTCKESAKCDNRGGNCVKADECDEQGAKRRGCDPCCSGVPSLDLGSKPQVPVCSLVRAGPCTPPPLDLEPLPCREAHESSGKHPVDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8B7</accession>
    <name>A0A3R7M8B7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001747">
        <property type="protein sequence ID" value="ROT75675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8B7"/>
    <dbReference type="STRING" id="6689.A0A3R7M8B7"/>
    <dbReference type="OrthoDB" id="19102at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="28359" checksum="4EA50F104E5DD96F" modified="2019-04-10" version="1">MGDIQQWFSSLPPMTRTWFGGTIALSLLGRFNMPSPYWLVLDYSAVVHGFQIWRLATCVFFYSVQRGFHFLINLYFLYNYSLRLETGLFARRPADYLFMLLFIWVCSLIVGLLGSMYMLMDPMVMAVLYVWCQLNKDTIVSFWFGTQFKAMYLPWVLLAFNVIMGNGGMVDLSGILIGHLYFFLTFKYPQDFGGVSLLQTPQILYHYFPNARGGESGFGRPPPAPRAGGDDAAGGGGGGGGGFFRGQGHTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBF4</accession>
    <name>A0A3R7MBF4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ribonuclease P/MRP protein subunit POP5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002195">
        <property type="protein sequence ID" value="ROT72172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBF4"/>
    <dbReference type="STRING" id="6689.A0A3R7MBF4"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016819">
        <property type="entry name" value="RNase_P/MRP_POP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48414">
        <property type="entry name" value="POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48414:SF1">
        <property type="entry name" value="POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023803">
        <property type="entry name" value="Ribonuclease_P_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR023803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="16319" checksum="710E2BF6FA8BD838" modified="2019-04-10" version="1">MVRCKRRYFVVEVVPEKSLDLTWYGLKNAIVDTVRRLHGDFGVAATTLGFQIKYCNADTLIAFISSTRGPHQLIAMALPHIKTILNQPVVVRTLHLAASMRHGFLFVKKHHEEKIQELEGKLKTHAEKEHWQHVKKKPYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCM4</accession>
    <name>A0A3R7MCM4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_008645</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002087">
        <property type="protein sequence ID" value="ROT72941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCM4"/>
    <dbReference type="STRING" id="6689.A0A3R7MCM4"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF191">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0050">Antiport</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10 11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018711441" description="Sodium/hydrogen exchanger" evidence="14">
        <location>
            <begin position="19"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="480"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="15">
        <location>
            <begin position="175"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="586"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT72941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="680" mass="75141" checksum="E4C689CEB68E1BD4" modified="2019-04-10" version="1">MRWSFLIVVVVSGSLVLGQDAGGSIEKEAEKSPKDEAQEAGPKAQVNQPSSRNSSDFQTGDGRNKSSISADAAAVTTTEAPHLGLHVGNSSIDNVCNITVEDYSKLTTFYPQHCSKDAEPEAPEADGGTVDTDSSNETVSCQSSVDLPAVGAAEQEHLSSLSIFLILCVLAMCVILIFFLLKTKLNYLPESVACVIVGAVIGLVLKIMYSQNIANWQKEEAFSPTVFFLVILPPIIFESGYNLHKGNFFQNIGSIVVFAVVGTLISALVVGGGVYLLGQADVVYKLTFVESFAFGSLISAVDPVATLAIFHALNVDQVLYMLVFGESILNDAVSIVLTSTILEMASPAMASMGSGEALLYTVWRFCVMFFASAGIGVAFALLSALTLKYVPVREYTSLELSMIIIFIYAPYTLAEGIHLSGIMAILFNGIVMSHYTHFNMSPVMQITMQHLMRTLALIAECTVFIYLGLALFSFRHQFHIALVLWSIVLCLLGRALNIFPLSWLVNKFRDHQINYKMMFIMWFSGLRGAIAYALALHLEFSDEKRHVIVTTTLIIVLFTIFCLGGATMPVIKYLKADKRQKNKRQKERDKELTMSKTREWGQAVDSEHLSEFTEEESDTPVGTQVRGFLRLDLLYLRPFLIRRVTHQEVRSHAYDLKKQCYQSINVQPSDSEEEELFSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIS2</accession>
    <name>A0A3R7MIS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001494">
        <property type="protein sequence ID" value="ROT77682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIS2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="558"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="74421" checksum="E70B37C85C0A6669" modified="2019-04-10" version="1">MLPLAALTPVSPAAVPDDARPPSRPPAHAPSPPFPSPPAGAFPSFGPFSVASMIPGARGLTIRPAAHPQPPKDCPPPMDLGEMPRPHHAGTLHQQAVQQGLQQGLQQGLQQGHQQGIISKDSISRGRISQGFSRVSINRGTSKGSISRPINKGFSRDSTSRVSISRAAPGAAAARPSAGQQPAAAAGRPRSRPRTMARTTWRASGALARRRPAAARPELARAEPPRPPEQERREECRMSPQEEPRGGKAAPVAAPPPWHRGLEGLSAERCRAWARYLAHNMLAQSQSPPPERHLPGDGLPPGLASKERPLAPPLPIDKVTITPTTSPDTPVRSPHLEEGSPRAQPPIWPKRRQSFSCSDAHIQKLLRTDATQGAPQSTPLMRLGDLGLDLSVRPLHEAFQHRLQPFPPSGRSLHALGLSRALFLTILTCAGHTTARHHRLRFYLFLSVIISSKATTPPHYHYYLLALPSIPPPSPSSPPCSSTHTRMSLSLLIFLYPHSSRPPFTLIVSVAPSHSRLLSLSLIHTCTLFLALLLALSLPLSFPHSLPYESFPSTFLRLILHTLSPLSILLVHGLPLFLVFFSGSSYHSSPSPSPSSFSSSYPSSSLYSLRLFPLHSPLPFLSPLPSSPFASPPSPSLSPSSSPPFLPLSLPPSLRPLFPFLLPSPFLSLLLLPLPSPSLSPSHLPSRQGWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJW0</accession>
    <name>A0A3R7MJW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA-directed DNA polymerase from transposon X-element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023137</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000650">
        <property type="protein sequence ID" value="ROT83686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJW0"/>
    <dbReference type="OrthoDB" id="6380262at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="42365" checksum="538331F71D62E7B3" modified="2019-04-10" version="1">MRSPRKAPGSSQIRRDALIHFPDNLLQALTHLYNASLASGYFPSCFKTALVALIPKPHKDLTDPKSYRPISLLEFLSKIFERIINTQLRWYLEDHTLLSHKQFGFRSHHSTQDALNIITNYVHNNKDRRRKTVLVTKDVERAFDTVWHAGLKYKLCTKFNFPPLIKILLCNFLDDRKLKLKFLHHVSGTIRMHAGVPQGSTLSPTIITLYTNDLPDPTHTDSLTILYADDCTHLARHDALSGVVRRINDELDTVSRWEHRWRIKTNATKTKVLFLNPRKRPPYDNIYLNSFDRLQAPLQITHSCTILGLTFDTDFRNNASPCLLHSEGTRPLQCLTTTFELGSEGGRRWAGTAKQGSKGQGGAKRGKSEGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKF5</accession>
    <name>A0A3R7MKF5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein kinase PLK4</fullName>
            <ecNumber evidence="2">2.7.11.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Polo-like kinase 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 14">Serine/threonine-protein kinase SAK</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_002201</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.21" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001294">
        <property type="protein sequence ID" value="ROT79073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKF5"/>
    <dbReference type="STRING" id="6689.A0A3R7MKF5"/>
    <dbReference type="OrthoDB" id="10004143at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13114">
        <property type="entry name" value="POLO_box_Plk4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13115">
        <property type="entry name" value="POLO_box_Plk4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.120:FF:000001">
        <property type="entry name" value="serine/threonine-protein kinase PLK4 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047108">
        <property type="entry name" value="Plk4-like_POLO_box_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000959">
        <property type="entry name" value="POLO_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033699">
        <property type="entry name" value="POLO_box_Plk4_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033698">
        <property type="entry name" value="POLO_box_Plk4_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046437">
        <property type="entry name" value="Ser_Thr-PK_POLO_box_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18190">
        <property type="entry name" value="Plk4_PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18409">
        <property type="entry name" value="Plk4_PB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82615">
        <property type="entry name" value="Polo-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51984">
        <property type="entry name" value="CPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51985">
        <property type="entry name" value="CPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50078">
        <property type="entry name" value="POLO_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="14"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Cryptic POLO box 1 (CPB1)" evidence="21">
        <location>
            <begin position="715"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="domain" description="Cryptic POLO box 2 (CPB2)" evidence="22">
        <location>
            <begin position="831"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="POLO box" evidence="20">
        <location>
            <begin position="1023"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="290"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="384"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="642"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="938"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1002"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="454"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="505"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="575"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="590"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="610"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="938"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT79073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1116" mass="126306" checksum="ED9A1EE5A0D56578" modified="2019-04-10" version="1">MNKKNEIGGTIQEYDVGEQLGRGGFATVYRARCRNTGRDVAIKKINKSEIAAGGLINRVRQEVTIHSKLNHPAILKLYAFFEDQSFVYLVLELCSRGELQKHIKSLRRVLNEDEAREYLSQVVAGMLYLHSQSIMHRDLTLSNLLLDNNGKIKIADFGLATQLRRPDDRHMTMCGTPNYISPEVATRSSHGLESDVWSLGCMLFIMLVGHPAVFPFNFSTRVGIEPVIPSYVTANARSLISECLKKNPRERIKLQAIPHHPFMAVGGKTDISRTSDSGLYTMTTVATTQHTRPPLTTISESDLSDTESSGSENRQGGHHHRLPYLRHPPSPPIRMKSNPKDLLPPNAGVIDTLKRKFTPLPSLQRGDFGHSNMPMPPLIRRERDVSEERQKHQLMYSQKQSSHSDDRSDSSQYSSSHMSDEAYHYHSGEKRSSRTRDHSASRSQDYHSAGRSPSRRERSHERYGSAHREVSDNYRIHSDTEEAKERGGHPRSRSKQRSYCQDYPQKSEKGNRDAYHSEERKEHYRYGRPSERHDERPHREHSGHRHRESSKDRYSERNRDDEYQRNRSRERHQHYHSEKTNRRRDEEPYNQKTHPCCESSQHRSWCKQKGRNDSEKNVSNYERSRYTSRCENDRYGASDRVHVPSQHRHTQHEQPVRAEGSSSRDINILGDLAPVKNSVQSKKDSEDARPGHGGTVHEQHPVTPTKRKPDLNCQTLKQQVSPLSSRRLKPIRQRTKNAFLNILENGEICLEFLRNMKGQEVVADVCRISPDGMRIVLYQPNGGSGLQPGSAPPPLPTEGADSIYGYENLPAKHWKKYVYAARFVKVVKAKTPKITYYSDQAKCLLMENSPDPDCEAIFYHGTKITKSGKNVMLTETTGVVHKIPQPSGHHNLPEQLQPIYLHFKQIHEHCLYLERVLSEVVEKTGLGCFPIIVGRKPASVSATPPSSARSSSSPREDKENLSPVSVQSYKLPRNVAAQLGSFEGSVASVQVEGNFVPRLRAPLNPHIPRNDSKGTTGSSKHSVSRVYVHNIGWASQDEEGQVSVEYLDGTQLQVSSNSPKVVFTDASGVSATYSSNDKLPLSVQQKLSQMQVVLTSLARPTDSSATPRLTHPVGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKK0</accession>
    <name>A0A3R7MKK0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001280">
        <property type="protein sequence ID" value="ROT79180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKK0"/>
    <dbReference type="OrthoDB" id="6020705at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052212">
        <property type="entry name" value="PH-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12156:SF5">
        <property type="entry name" value="FI18040P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12156">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="21210" checksum="021F70177B526011" modified="2019-04-10" version="1" fragment="single">AEGTVAIVDGEGKCSNKVFEDYAIRNIQDTFNIDDVPGEIDRLKELKNEAMQSVTDLKRSVSELEMTEDEALRELEVERALLEGELVPLREKLLADEERLEMLLQQSSALEEKCQQERSHHQQAIEACQTRLEQAERELDMLEGRSENFTGTTDEETEMLETLKAQHEAVEAERKVGVKKLRMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLQ5</accession>
    <name>A0A3R7MLQ5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Signal recognition particle 14 kDa protein</fullName>
            <shortName evidence="8">SRP14</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_001081</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SRP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001144">
        <property type="protein sequence ID" value="ROT80191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLQ5"/>
    <dbReference type="STRING" id="6689.A0A3R7MLQ5"/>
    <dbReference type="OrthoDB" id="19209at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT80191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="29408" checksum="C61BBD1187344E60" modified="2019-04-10" version="1">MFHNSRKEGQVSVTVKRYDGRTRPYPKPRKLKNGKMSKVEPLPEPEEYSCLLRAKTRDKKISTVVSAADALKFQLQFAQFLQRNTLLHTQHSPLARATLNAHSLSLSLSFDTLTLSFTSNSQLASLSVSSTRHSLLCLSLRATSHISLFTRDFYFSLKHTRATLSLILQRAHSLFSLNTAHYLSLFYTRINSAHTFFYHAHTLSLTRAHSLSHTRHTRARLLSLIRALKRAHSLSTRNSLSHTRTLSLSLSHTLSLTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MRW4</accession>
    <name>A0A3R7MRW4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_022472</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000559">
        <property type="protein sequence ID" value="ROT84341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MRW4"/>
    <dbReference type="STRING" id="6689.A0A3R7MRW4"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051093">
        <property type="entry name" value="Neuroligin/BSAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43903">
        <property type="entry name" value="NEUROLIGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="747"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="222"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="612"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="812"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="820"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT84341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1078" mass="122241" checksum="17962FE823A5E7C2" modified="2019-04-10" version="1">MLTFNVCRLGMARNNFSFVLPGSVRGKLDGRQGFTPEVSTSASHPLSFPSLSYAHRPPLSTFHPPTALTCLLERPFTAPNPPTALRPPPATLHPPPATTTTLRYPPPTTPLPRYPPPTTRYPPPTTRYPPPTAAAPVPAWAWESPSSASNETREVDTHQPPPGGPLRHHRQREGAGLLRVPVNDDRARAPIRRGHVNATKHIMNLPRPLPSYGPPRYARQNVSIPYARPPIEEGRFKPPRYVQHWFSTWQALDYRPACPQNLKYIGSSNGIRNGIHEDCLYLNIFTPSISIGVTDQYPVMFYIHGGDLEHGASNQFPGHMLAGWGEVVVVTFNYRLGALGFLSTGDENSPGNYGLMDMAMALEWVYRNIRFFNGDPQKITVFGPGAGGAMAGILAVLPKTKDWVHQVLAESGSPLADWAAIDDIYRVQNTSRVYGLEVGCTVESSYKLLQCLNRRSYEELASAPIKPDIGTFAWGPTVDSKFRVPGDDWYEDWKEEDWHILPELPIKLYEKNHHHSDLHYLTGVNRNEAAKMVFDDNRLIRERYEVTEDFFNERVKEWVKHYNYSLNPEVVVRCSLQIRRRPNGEGPRELHWEEECSYLLLNTTVDALKLDYWREVPNNIEYYFVFGAPFMDPEFFPESIRVARNLWSEGDRNISEFMMKTFVNFAKWGNPTQTQVQIIKVNWEPVLEGNLKYLSINTTFNTSMHYNYRQTYNTFWTTYMPQVVREWVPTVPPPINPWIHMTEPIVAAFYGAAAVAVFLLVILFVCCGLWKSAKRQRNKALDDLQYYSTENLTPQQESEDYKVREYLNKLANNNHDETPSRSVTPYTVASTDPIIQTDHNNTKSRDPYQQSYYKDTKTAKSVDQLEQPYRPGYQNMMPSSRSAGNIIENYHTSYHNPGAELNGHYQPQQQRSITPTSTIHSEPNGKPTTQYMMTQQVTKPPEKEVRAVPQPATRVSRSVATITSTSVIIIISCAVHNADIKASSQHVPFNADIKRPHPCAVHNADIKASSQPGNHNADIKASSQPCAVHNADIKASSYTMNLYPKEVKPTSLIFGNLSLRFVYVSFTFMSVQSLCKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MUS2</accession>
    <name>A0A3R7MUS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dual 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002448">
        <property type="protein sequence ID" value="ROT70237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MUS2"/>
    <dbReference type="STRING" id="6689.A0A3R7MUS2"/>
    <dbReference type="OrthoDB" id="6373854at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="170" mass="18216" checksum="4E347B2B3B13598A" modified="2019-04-10" version="1" fragment="single">DEDVRSCRSAGMESRPLPVLVLSSQTSHSPRILQEKATPPVTWHQYRYPGWGSHSDEVKNSQGGSDGSAGDPSAVPGAMPIGGELTVGGAGGGASHSPLLNYDPECARMEAWLDEHQDFVHDYFIRKASRHMVDALGGQPPGSRASSGEWLRAQAGAGREPFRWGRCCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MZ41</accession>
    <name>A0A3R7MZ41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative intraflagellar transport protein 80-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MZ41"/>
    <dbReference type="STRING" id="6689.A0A3R7MZ41"/>
    <dbReference type="OrthoDB" id="408728at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000298">
        <property type="entry name" value="Intraflagellar transport 80 homolog (Chlamydomonas)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24098">
        <property type="entry name" value="OUTER SEGMENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24098:SF0">
        <property type="entry name" value="OUTER SEGMENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="220" mass="23973" checksum="4A7980DCF5EC373B" modified="2019-04-10" version="1">MRFKTSLLNKPKHTDLVSCVGWMSPDEVYSCGDDQQLLQWNLLSGETTKVSDLPKDVYPLDLHWLPKTAMQKSKVGSEVFLLTAADGKFYIVGRSGRTDKAVEAHRGAVLAGRWSHDGAGLVTAGEDGLVKIWSRSGMLRSTLAQVPVPVYGAAWAPDSDAVIYTSGYNLIIKPLAPNSKPIQWKAHDGVILKVAWNPNTGLILSGGEDTRLLEPVEMGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NN04</accession>
    <name>A0A3R7NN04_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003730">
        <property type="protein sequence ID" value="ROT62321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NN04"/>
    <dbReference type="OrthoDB" id="6350208at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF26">
        <property type="entry name" value="RE23625P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00299">
        <property type="entry name" value="ACRYSTALLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="668"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="169"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="217"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT62321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="761" mass="84742" checksum="5541041B1656EB1F" modified="2019-04-10" version="1">MASSDDVGLSRSSIKCRRCAGSPLSSWDLFLPITRRGSFFQDSFFSNIHHDFDAAIREVLGRWNEPDLKVTDSRDDVSRRYRRLRSQNMNEESQAVTVTSDNTGHKEQKSTSIPVNVEETQTVSSSASGEATLRGSETSEKECQCLRCSLKNIYDKRTSQTADNALSSARSQSIDAQVIQDSSASSGAQEQMQSKQEFGVTAPRTTEAVGSESSSTVRKENRADADSRRIRRDSWDVFFPITQRGSFFQDSFFSDIHDDFDMAVRKALSRWNNTDRRVEKDLRQSDVLDRYRELRPRDLKEENLAITVTSDSTSHKAEFQQKTKIIPIEVEEEAQGAEPLPASVSMPNVPLASTTSSSKSFVSQGVVEDSETLRRQEGVKIPINEESETSFEEGQMMRQNVTQVPSGAVSESRKVVISGSDIGEASEEASVSRKSHLSFESQSTRDKAGEICTSLRSRHLGDDTQAVTSSEDERYHKEIGGSLAHESHVSALSKSSLESIGQDPTTVLTTMRNIKEQIIPLNVEDSERENVAHFGSSSVQVSDEAHRAGYTASSEDGDMFIAVVKQPDYHYKVVAQEGEGEEALGNGHLDIQATQQQRTDLGRESKTVGITSGSGYLPISRKGPFDSDYFFENVRENYSQAVREVLEKAKEWSCRSDAMQNYRSLRQRNLRLDNQAVNISEDQHSHKVVMDVHDFTGGDVTVQLVGGNELLVEGQAERQEDNKVSRLSFVRCFPLPDHVDRDAITTALSSDGILTIITRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NNG6</accession>
    <name>A0A3R7NNG6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative tenascin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019597</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003633">
        <property type="protein sequence ID" value="ROT62552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NNG6"/>
    <dbReference type="STRING" id="6689.A0A3R7NNG6"/>
    <dbReference type="OrthoDB" id="6347199at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF394">
        <property type="entry name" value="ANGIOPOIETIN-RELATED PROTEIN 3-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018546266" evidence="2">
        <location>
            <begin position="16"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="3">
        <location>
            <begin position="180"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="483" mass="54172" checksum="FBDC047B5898FCA1" modified="2019-04-10" version="1">MTFVRVLMAWLCVWAAQTTSGLESSLEALPGTLYSDILDTLGDIGEGIPFALPFTSRDSHNARQDTTDDPFSDDKDPSPEGGVALEPPAVGERDVPEAETAGEGEEEVNKEEQDAAHNLTTAQEEEMAEREVLRRKIWELQEANRNLLGQILLKDRRYPNQTGIQQPFGTREDDQSPSKGLKSFRPADCADHLVYGATVSGVYDIYPFTCLCTKPIQVWCDMDTDGGGWTVFFKREKNHVQERFNRSWSEYKDGFGNPSSEYWLGNELLHTMTSSREYTLRMDLQLSTGDFKSGVWKRVLVDDEIQKYKLTLSNYSPESSTTSNCMSVSHNRFFSTYDRDHDSSSRCLPSRLDVRCRRLECEVSVAVAKGDETRDLREIQRSGYRSLWCMAGTSIAVPLVGLCVRGSQASNCAAIKQGGWWHYSCSSSSYLYPTSSYPSGLVSTCYNGQGVMANWIQFKLRPAVCGTSFKTVYLNSYACDSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NR93</accession>
    <name>A0A3R7NR93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003233">
        <property type="protein sequence ID" value="ROT64561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NR93"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1222" mass="131449" checksum="2402DE6F5B669AB1" modified="2019-04-10" version="1">MVLIVPPSSVAPGLASAPHQFDLGLESAPQSCILVLAISLFAPVLCLPPVHHAPGPAFRAVISLHLSQSARISCPVRLRARHQLHLFLASAPSSVALVLAIPSVHQLHLPCLPRRHQLPPGPCLPAAVISMRPVLPSAPSSVAPASFQSARISLHLALPSAPSSVAPVLCLPRRHQLHLVLAFRAVISCTWSLQSAPSSVASLVCNRASSVHGRLPAFISCTWSLQSAPSSVASGPCLLHPSAFRRHQLHLVLCLPRRHHLHASAFARPSFSWLPWSLPRASFSWHLSLCLPARHQVPPCLCNPRRFMRVHRSLPLPVAVCHHVYSPASFAFPASIELHPMSLHSAQYRAPDISCTLIIASAQRNQSAPPVLALRASIHSSPGPLSLPNLSVCTWSLPSVPLHNSTFLPSPRLISCTLGPLLPRPVLYACNLSFLRAVISCTWSFSHLPLAVIKLQPFLSAIPPVSKFPNLSFYGLPASFSCTWSLPPARHQVAPVHCLPTPVISAPGPCNRRLASVHLPLQSAPYIMIAYLSVANPAPSYQLHHFLASVPSQSFTLPSYAKISSPSSSSSAPRSLQSACHQLHLSCLRADHQCIAPVLAISHARQSVAPVFAIRPHQLHLAFAITRRVISANLVLLTLPLHEYTSSTMPHTGLTSPPSSVAPGSLQPPSSYHQLHWSFASAVISFHLFLAIRASSVAPGPCNPSVISYMTCPTLTALSSRTCVLASARHLDAHLGPLPYRTSCHQVHLSPCSAPLIAPVLLPRAVISYAPGPAFAPSSGMHLSFPRAVSFTAFAHPAPLSAPRSYIASAPDPSVHPVVPMQSAPSSSASGPCLSALSSLQILILDYRSRHQFQYLDPCSAPHHCNLSLPPLPGISCTLVLLTFPAPSSLHLVLCLPRRHHQLHLVLAIRGRHQLHYWSMPYPRRLSFQPVLCTPTVISVAPGPLLFHRAYRQLHFDLVLCLPRRHLVAPGSLAFPRSNQSLCHLSSAFRCTFYTVHLVPLPSPPSSQLHLSLPNIRADHHSPVLENPSTIRSVAPGPLPPSVPSVHYCSMPSLLITLHLSLVNHAVIQLSFSVPCNRASSLAFYTRFLAIPPSSVAPPAFRASSDASVPLQSALRHQAASGLGIRAVDQLHLVLAIPYASSVASVLGNSALDHHCTCSCNTAPYISHHVPLQSAASHSLTFRSCNRLTHQLHLVLAIPHRLPVMHLGTLQSRAVNTVAPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3M6</accession>
    <name>A0A3R7P3M6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001879">
        <property type="protein sequence ID" value="ROT74547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3M6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="517" mass="55751" checksum="4D42735B9E5905FA" modified="2019-04-10" version="1">MAAYTTLPVALQGHKRAFNTLNSPWLSAAPSQTHHNFPSAITVPAAPSPSEFYHHHCRQYLSVPIAFAPPPSPTIPAAHLSRNINFISPFPAGGRALRRIGVCDLPAALNLLVSREGKNACCSAATQDSCCRRVLVTRSSPPSPPLSLPVSPYFSLCFLSGLRSDTRPLMIVSSLLPLHSLLPTPRYLPFFFTLSPLRSIPVLISLPPHSIFPVCLPSSSTLPSRLSPSPFPSLFSPVCLPSSPSPPVCSSLLLTLSPHPSSPSDLPFLLTSSLLSVLSPFLLPLSPPSSSPFLLHLSLPIFLRSASLPLHFSPHFFLPVASFLFTLSPQLLSPPRIRRKNTGGEREKKQLKLDERSPERKQSPRGVAASPLHSTLFHTTFTRQRRAAMAPKGRPLDVLTIAPSNDRCPAPAATSPAEATLVSTPTPHPPPRLSALATNTSSVSPSPRRPYLALPTSSSFSTPRTTAFRLVATNELRRPPEKPNKSRPEKHTGQKVAAAQAVTRSPEYTAASDAPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAF4</accession>
    <name>A0A3R7PAF4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rap1 GTPase-GDP dissociation stimulator 1-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016834</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003119">
        <property type="protein sequence ID" value="ROT65213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAF4"/>
    <dbReference type="STRING" id="6689.A0A3R7PAF4"/>
    <dbReference type="OrthoDB" id="26149at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040144">
        <property type="entry name" value="RAP1GDS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10957">
        <property type="entry name" value="RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ARM" evidence="7">
        <location>
            <begin position="362"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="609" mass="65069" checksum="0276D7B7F64D7788" modified="2019-04-10" version="1">MCIFTEELTASLEKLRVASENPSPEPLDELINYIHQQEDSTTVCEELVAGGVLPLIAGSINSSSVEAQGKGAELVAELAKVESCRLGCVTSGLVPILVEKMSSTTTGVALQACRALGNICYEHDGGRVSVMESGGAAQLLHLLQRAASLPNTPDDHQLRLVATGFLLNLLNSYDTVQDQSMEAELVDVLCQYLDKFAEDEDIPTHVLLSLTCMADTEVGRGLVVSRDITPQLVRVLKINESAEVTETCLELVTNLAETECVKTQLAVGGVCEAVVEVVRRHRNNPASDLSPPIIKTATDLIVLILVGDESMGIIYGDGSGSVYQELVGWLTSDLEDLQIAGALAMGNFARSDAHCIKMVESGIADKLLKVLSSHNSGEGDIRLQHAILSALRNLSIARQNKPVLVQQGALEVLLPMATAIQTFPVVFKLLATLRMIIDGQTEAAVKVGSNNEVVERLVVWCGTMDHPGVQGESSRLLAWTIKNCGENTDVITALINAGCVPPLVLMLGSEHAVMVNEAALALVLVFSSVVDPEVVEKTKLPQVATYVLNNPNLPPEIVANVLSMLTAIAGKDTGIECLKKDELKTAIDALTAHANEQVKTLSTALKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDE0</accession>
    <name>A0A3R7PDE0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019984</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003781">
        <property type="protein sequence ID" value="ROT62184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDE0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="446" mass="48453" checksum="2AE6491A1D71599F" modified="2019-04-10" version="1">MSTVRIDVPDSLDAFVYVAFLSLATRSPALTLRHAYCHTTLVSPTLVPRGSALTHSPAYSTYVLIVSQCSVANLLLSILPHYRSHYVPFSPLSRGSCSIGILLVTASSLPQRLRPHYLPTLSPILYPALSLPRLPSSLAHSRVFPDCFHILCPLSPPYAHPSTRSVAIGSPPRRLTFDERHEIDTFSLHSLRHSSPLAPPALIRTCSTPALECDVHYSVAQLICPHVAPNYDSRLNLRCQTDLLAPLLPRVTGHYSSPSLPTSGHHCSHPSLSRPLTLHPVSPANSHRPYLSPNSFSYSLPPTLSLFSSAPLSPISLRTRSPPHLSGPLKYVHLFSPHICTPTASTGLHARHISPGQLSAPRSYVPRLSVPILSPFSPLFSPQLSHPLSPPLRSSLILSAAILYRSPYVMPSLAIFASPPTLSPILLPTLSAIFAHSRFPISPSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDG6</accession>
    <name>A0A3R7PDG6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002810">
        <property type="protein sequence ID" value="ROT67417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDG6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="44232" checksum="955FC2303300E101" modified="2019-04-10" version="1">MSSLPMEPIVKFTGYNYPPEQLFLETENFIASLDPHIQRGSYEFDKRCLQHVTQRLDLTNPAVSAMLSGLTKDADRGWHTFKEQLSQRDITEFYVKVKQAIDDFLELLRRDEHMMIAHEHLEIILPQIRMLLAEGIVFDCLPAKLCTNAQIMYTRPESPGLLPTHLAKACGFVTNSDTAIPAVVAHTGNVSFSSTPTPRRDLSPAPRQTRRESRSPDRRDSRPEHRRPSRTPSRHSPSPEVRPARTGVYVTSPRQPDDTSPCGAPLLPIRVGSHELLAFLDSGSAVSIIPVSSLSKCNTPSACTPTPYIVHGASGSCLDVVGEVSLTIHLSDVPIPHPFVVINGPAVPGDILLGYDFMAKTGLHQIPRENVAVHFGRVYALTPPEEYGADRTATQSQKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE92</accession>
    <name>A0A3R7PE92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative neuronal pentraxin-1 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_019234</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003527">
        <property type="protein sequence ID" value="ROT62898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE92"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051360">
        <property type="entry name" value="Neuronal_Pentraxin_Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277:SF125">
        <property type="entry name" value="B6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277">
        <property type="entry name" value="PENTRAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pentraxin (PTX)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="10">
        <location>
            <begin position="173"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT62898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="574" mass="64708" checksum="731B35589A0FF836" modified="2019-04-10" version="1">MVGVFASSGEDGGNNFDDLSSAKRGEGHVLLYNGKIQYAFSNLTSEIGLHQWTHFCHVFSSGKYTAYVNGEVRAQGPLDTATIPIPLNSTIIIGQEQDSLAGGFDKSQVFRGHIAQVNLWNSTLSGDAVRQLATCDSNLAGNVFSSDREELELLNVTVAEWDLADLCSKVDEYVIFPEMRNLKESRLMCHRSGGEIYAPDTRQKNTALHSSSLQFSKACFSNFHLWLGLSDEENETVWRKFSDGSVVTELPFSHDQPNGERGENCMFMSLIDGLWTDTYCFRVWDACVPCEKDLSRPLRLRGLCVKEELETVTEATRPGNRETRSPQEAEGDSRTEPRTTAWTDEAGCTLIELPRSYRRRGPPRARAGRPVELDAAVEILRFVTISDVNRLVRLELNVEITWKDPRLRFLNLKDVLEWNKLSEKEAAMIWRPKLEFPNVFDGNVRLLREGVYVRKTGKQEDVDPNDVQMNTVYAGDSAAFVQTQHYSGSFACSFDVFFYPFDTQRCSVHLQLSSLRLEVVKIAGERAKVTYLEDKQLPSYTVTKYYAQDSFRGNNKTRYSVLKVCFGSGRVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEM5</accession>
    <name>A0A3R7PEM5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Serine/threonine-protein kinase RIO2</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">RIO kinase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Serine/threonine-protein kinase rio2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_018760</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="17">Associated with late 40S pre-ribosomal particles. Interacts with PLK1 (via its N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003448">
        <property type="protein sequence ID" value="ROT63355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEM5"/>
    <dbReference type="STRING" id="6689.A0A3R7PEM5"/>
    <dbReference type="OrthoDB" id="10258631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000053">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000307">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000052">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="22">
        <location>
            <begin position="66"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="330"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00064676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00068837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00076005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT63355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="484" mass="56242" checksum="723D60F5D9C19780" modified="2019-04-10" version="1">MGKLKVAMLRYLMRDDFRILTAIEMGMKNHELVPITLVTQIANLRGGGVHRMLRELCKHRLCAYERGKHYDGYRLTNMGYDYLALKVLSSREVLGSVGSQIGVGKESDIYVTSDPVGNPLCMKLHRLGRTSFRKLKEKRDYHHHRNKASWIYLSRLSATKEFAYMKALYDRGFPVPKPVDCNRHCVIMELVNGYPLCNVHDVADVPQLYSDLMDLIVKLASHGVIHSDFNEFNIMVNDDDKPVIIDFPQMVSTDHENAKMYFDRDVNCVREFFKRRFGYESELYPDFDGDVVREEDETTKEQDQTETTGLKKEELVRLQDEMETLCKELNIEKNLENDESEELNKDTKKEEEVEETPSEVSERHSRRKKGKDADRDARLLFIKQLAKARELRQHCEENGEEAPPLEDMIDDSMSDIHSVRSFSTTASTIEPEEIKRRLQKDLTRREKKQVSKKNLRVKGEANAYRRSKLANAATIKESVGWDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEX6</accession>
    <name>A0A3R7PEX6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000555">
        <property type="protein sequence ID" value="ROT84372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEX6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="43972" checksum="61D53899DFD7CB7D" modified="2019-04-10" version="1">MFTGFVSWTTLGRLGSLLGSSPGSLWVRLLVHSGSSPGSVWVSSPGFTSGFVSWFIWGSSPGSLWFVPGSLSGSSLVHSGFVLSGFVSWFTLGSSPGSLWVLSCSSGSLWFTRLLVHLGSSPGSLWVRPPGSLWVVSWFHFRLLALVRLLVHSGFSPGSLWSSPGSLWVRLLVHSVGSFSWFTVGSSPGSLWVRLLVHCGFVSWFTVGSSPGSLWVFVLLVHSGSLWVRLLDLWVRLWFTLGSSPGSLWVRLLVHSGFVSRFTLGSSPGFTLGSSPGSTLGSSLFTLGSSPGSLWVRLLVHFGFVSWFTLGSSPGSLRVRLLVHSGSSPSLWFVSTLTLGSSPGSLWVRLLVHCGFVSFSLVRLLVHSGFVSFLVRLLVSLVLWIWVSSPGLLVSWFMVFVHSRCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG00</accession>
    <name>A0A3R7PG00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_011171</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002412">
        <property type="protein sequence ID" value="ROT70564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG00"/>
    <dbReference type="STRING" id="6689.A0A3R7PG00"/>
    <dbReference type="OrthoDB" id="250802at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098793">
        <property type="term" value="C:presynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097401">
        <property type="term" value="P:synaptic vesicle lumen acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2950:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT70564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="13751" checksum="2AF90AA8F3370BC6" modified="2019-04-10" version="1">MASQSQGVQQLLAAEKKAAERVAEARKRKARRLKQAKDEAQAEIEKFRQERERQFKEYEAKHLGSQDDIALKIKNDTHIKIDAMNKQVAYNKEAVIKRILQLVNDIRPEMHINAKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGW2</accession>
    <name>A0A3R7PGW2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Actin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_015888</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGW2"/>
    <dbReference type="STRING" id="6689.A0A3R7PGW2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000205">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000158">
        <property type="entry name" value="ARP1 actin related protein 1 homolog B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT66120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="13438" checksum="4C411F5B01212A39" modified="2019-04-10" version="1">MTQIMFESFSVPATYITIQAVLSLYAFGRTTGQVCDSGDGVTHVVPVYEGFALPHAILRLDLAGRDLTNYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFESEMNRCCFLFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHY0</accession>
    <name>A0A3R7PHY0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipocalin/cytosolic fatty-acid binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009117</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002142">
        <property type="protein sequence ID" value="ROT72500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHY0"/>
    <dbReference type="OrthoDB" id="6359662at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018775758" description="Lipocalin/cytosolic fatty-acid binding domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="245" mass="28183" checksum="6D331BD02D0B1E8B" modified="2019-04-10" version="1">MQTAILVVVLSLAASLAASYKFQGLWYAVEMFTTNSKCVTLTFNRLGKNDFKVTEGREFVAAQVVGIDHSFKTKGVYNSRAPQQPAKFHARWSNNIWQQPEAIIVDTDYWQYAVIVECQSVMYFMKRTSAVILSRKRDLDLRVLNQVKRDLCDGYGFDCKDFETIDHNRCTSVQREPARKDVARASPLNRPKPLRKFPMPEVVRTTPSSKIKPRTFRPITQKPTAAPTTPRVYGKLQRWCLDFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIK5</accession>
    <name>A0A3R7PIK5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ras-related protein Rab-28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIK5"/>
    <dbReference type="STRING" id="6689.A0A3R7PIK5"/>
    <dbReference type="OrthoDB" id="10254700at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="224" mass="24499" checksum="E5310CCBB0B8BF50" modified="2019-04-10" version="1">MSDSEDEAVERQVKVALVGPPQVGKTSLAMRYTQDTVNKGYQASMGVDFYLKRLILGSERNVNVQIWDVAGSSLAGKMTDKYLYGAHAIMMVYDVTVSHTLDSLQDWVAAARRAGRAQERPPILALVANKADLEHTRQVKSERHHRFASDYGMVSYVVSAKTGEGVALAFQKVVAELLGVRLTKAEQEQQQPVVTAEIVTYQEGAIPKIPVPATNSTSTVCSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ00</accession>
    <name>A0A3R7PJ00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002030">
        <property type="protein sequence ID" value="ROT73378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ00"/>
    <dbReference type="STRING" id="6689.A0A3R7PJ00"/>
    <dbReference type="OrthoDB" id="10015491at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="27"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="164"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="324" mass="35161" checksum="C61B91DBBC87F128" modified="2019-04-10" version="1">MRKANGTQGGSEASRSTGGECGGRRVPQSLTLPPAAGTQGARVRGVEVPQEARAGEDVSLRCLVDPWPDPLYSLAWWKDGEQIYRVAVVPTPPGDPHALPVRSMVTVFALPGLSLKRGRGGLGHVVLQEVTVAASGNYTCEAVADFPTFTQSMVSANLTVVDPPDTRPILAGYKGRYYPGELMTVTCTVLRASPVPVVTWFINNRKVQAGKNKVLEVRAEPDLTSTLVTRLTVHLKREHFQQGVLNLTCGARTGRSLWLSNTITTHHARHRNAPGYSTHYQGGAGGFDFDPGQERLLSGAPPRVSRIPWRWSLLFASTVLHFHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PM38</accession>
    <name>A0A3R7PM38_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002366">
        <property type="protein sequence ID" value="ROT70952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PM38"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13740" checksum="8144CE370269A93E" modified="2019-04-10" version="1">MLLESSVRCQDDQERRRRRRTFGGLLNQEKRRSGGGGGENRPSIPAEKGERQQHPVSSSRRGMSLRIVSYRNKPQLRGCEPAYFRAVLITPPRRPPARSDSWAAGSRPKPHITGGCLFAGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNH5</accession>
    <name>A0A3R7PNH5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cdc42-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009418</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002194">
        <property type="protein sequence ID" value="ROT72175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNH5"/>
    <dbReference type="STRING" id="6689.A0A3R7PNH5"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="60" mass="6813" checksum="EDE000074EE94B1C" modified="2019-04-10" version="1" fragment="single">FDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPV9</accession>
    <name>A0A3R7PPV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002031">
        <property type="protein sequence ID" value="ROT73369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPV9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="534" mass="58405" checksum="A8992F8489C776B2" modified="2019-04-10" version="1">MMFHGIRRLPIQRVESPTKKTSESEAGRRAGNKARAPFISAFSPPRCRRAPRNRDFIDYYTLPLSSSLSLLLPTPSLLSPRFPLIPYPLSSPLSLSLPHSSLPSFPSHSTPSLLPSFPAHSYPLSPLPFVLHLSFLLLVPVSCLPFSPHPLSYSILQKPENKKGKAHGKKYGKALGEALSVSLHSPGEALSVSSYSFNSQRRLRLPWAFGRRMRALGSCGDEVGDGQWELSPGSESRQLFKQEECERAACLSSALFLSAAGIALERTVDLKGLCRRWRGLEAEVVDGREGRRFCQELVRSNTQNRPPSLPHRLPSNPLQPPPPVPLPLPPSPPSPLPHPSPPPSPVPLPPSLTRPPSTRPPLPSPVLTRPRLRPPLTPLHPPFRQRPSTASAAVAFREGYHGHFLPSLSQLFFLSSFNASLPPSTFSFLSIFLSPSILTPQTSLTLPPLPSLLPRPSSSFPSFFPPPSTLTHISLTLPALPYLPFNPSLPFNSSLSFNLSLPSTLPLFLDLPFLSILPLPSSLDLPPPSPPFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQQ6</accession>
    <name>A0A3R7PQQ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001208">
        <property type="protein sequence ID" value="ROT79667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQQ6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="596" mass="64619" checksum="F208C183BD3F2F66" modified="2019-04-10" version="1">MVPTLFLRLSFGSFYPVQFRLSFVILCLRLPLSRFRFPTRAKSPNPKNDTFANRSLPRSLIREFPNTFTSFGPLPSPPPHGVPSSACVRRPLHVASPPHMRRSHGVPSHGVPFLLLHVASPPPHGAPPPHVHMASPPPHMAGVPPGRLLHWRPLLHMASPPHMASPSSMASPPPHGVPSSTWRPSSTSPSSTWRPLHMASPPPHGVPSSTWRPSSTWRPSSTMASLLHMTWRPSSTWRPLLHMASPPPHGVPSSTWRPLLHMASPPPHGVPSLRWRPLLHMDVPSSHGVPSFRMASPPGPLLHMGPLLHVASPPPTWRPLLHMASPPHGVPSSTWRPPSSTWRPLPTRPLLTWRPLLHMASPPPHGGPLLHRASPPPHGVPLLAHGVPPPHGVPSSTWRPPLHMASPPPGPYMASPPPHMRPLLHMASPPPHGAPLLHMRRTCRPLLHMASPPPMASPPPHASLLHMASPPPHGRPLPLVPPPHGVPSSTCVPPPHASPPPHGVPSSTWRPLLHMASPPPHGVPSSTWRPPFHMASPPPHGVRPTPGVPSSTWRPSSTCVRAPSSTWPPPPHGVPSSTWRPPWRPVTIPRYGGPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PR15</accession>
    <name>A0A3R7PR15_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001173">
        <property type="protein sequence ID" value="ROT79947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PR15"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="41476" checksum="4BD0A8E6664AED9E" modified="2019-04-10" version="1">MQAGPTGTYRLAGPSTWLAVAVCPSGPPGRPATKPVITSLEPTPPLLTHNTPSPELNPINPPPSAHAPFSHHPPSFVLFFTASSLHNFPPFIFFPSTSLEFFPPSVSSFLTFPFLHFFPFFTSFLLCFLLPPLFSFLHFSLRFPPFTFFLLLSLHFFLQCFFLLHFSSSIYFLFHFFLALPPFHFFPSSSLTSFSLCFSLLHSFRLLLLRPPLFLSPSLLPHLPPLTLPSIPVLLRLYLLTNPPPAPSPHLPLLPLLPLSPPSLILLTPPTRTQTATSFLPLTTSPPHSSTSPSQPPTLLPLSPPHPSPPTRNKPPKRRHRRRESLSTDKKTAVATPSPLPPLPIYPPPLPLPPPPFLPFYNAIVTRHFLAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTQ8</accession>
    <name>A0A3R7PTQ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative mutS protein-like 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001609">
        <property type="protein sequence ID" value="ROT76801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTQ8"/>
    <dbReference type="STRING" id="6689.A0A3R7PTQ8"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF21">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="8">
        <location>
            <begin position="651"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="819"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="899" mass="98101" checksum="B123470986F92235" modified="2019-04-10" version="1">MMSCREGKYSPGQACRYRVTPASIPIYTGGGAYITSVTPRSHGNPDDACRPLARRYCARLLLVDAVPLGHSGPLAFALLEYVHLHFTQVSLSNLLISLGFQPPSLSASSFPLRRRSSVLSLSISALVAFCGYYIEVAAARRLPRPLASLGSCTHPHADVPTINARLNALQYLVDNPDLFYTLQSILGRFPDIDWLLSMCAQLHKEDTEQRCELRLNYVISLKNTLELLDPLASTLADATDPLLDSVRQSVSRADLQELLETLRGVMHEDARLVKGAAAMRAQRCYAIKSHVNGLLDVARKIYSEIIDDITVDPSPSSHSCPKAIISHVASESRSLKVRYLQAQLVGYRVGVAKGYSSKYYCSLQSLSDAAHVEELAKDHNVGMRVGHNAARGFHIAIPVPKRKSAPNLPSVFIKVQRGRGCITCTTEHLYLLDQRSRDTLREILIMSNVIVSEMLIEARGRMGALHGLGEAIATLDLVVSLAHSAALGSWVRPEFSRALAIRCGRHPILDVLAPTPPVPNNTFLSPESRVMVVTGPNMSGKSTYLRQIALIQVLAQIGSFVPAEFASLRVVRHLFTHLGSEDSPENNASTFQVQPSSLFFPPLFPTTLLHPYYLYSPYDAIAVHKTFLRHLYGLSVMSDVAHMVDGAGSDSLVLLDELGSGTSVEEGGSLAWAVMETLVHARATTVLATHALFLTKLPYLYPTVVNYHLESEDEGGGLLRLSHVVRRGVTQATHYGLALAAVTAMPPSVLQRSRHLASVMAPPTQVRESSASRWKRTRRAYDTAQCIALRIACWLWPTPPATSSPSDDPQANYAALTPRASTSKALQPHSIDETTSEASPRESRSLGAHDLTALSDTRATELKTKLQCLLQDFMAQVDGGTLDAPQLSDEDGDGLQGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PU69</accession>
    <name>A0A3R7PU69_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative relaxin receptor 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000784">
        <property type="protein sequence ID" value="ROT82706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PU69"/>
    <dbReference type="STRING" id="6689.A0A3R7PU69"/>
    <dbReference type="OrthoDB" id="6022531at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050328">
        <property type="entry name" value="Dev_Immune_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373:SF383">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373">
        <property type="entry name" value="SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="89"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="216" mass="23768" checksum="F1908D3A9AF4314B" modified="2019-04-10" version="1" fragment="single">AGGERGPEARHFPHASPALASPHIAPPPLTMGVNSRNIAAYGRAGLVLLLGRFSSAAILKPVFEDGSCERGWFSCGDNGTHCIEQRFLCNQEEECPEGEDEEGCVNDKGDNQVMKKILSKAVFPWQDRHRCSLTKYPSACVCRKLTMLHCPGIDILEVPQDIDPAVTALLLQNNSISLSRNSFSRYPQLTLLHLESNNLTQLPDGAFHGLNHLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWH5</accession>
    <name>A0A3R7PWH5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001979</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001261">
        <property type="protein sequence ID" value="ROT79299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWH5"/>
    <dbReference type="OrthoDB" id="6366643at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF38">
        <property type="entry name" value="IONOTROPIC RECEPTOR 100A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="10">
        <location>
            <begin position="403"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT79299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="78070" checksum="FB9369F3F0722DB1" modified="2019-04-10" version="1">MEQTPTRIRESPYRSSRRWLTDPTLTKHFRLTSAELRARARGAGLLHGPHGKRSRAHQVSSVAQATLSDALVSHPREGDEASLMTLTTHTLAAVLEASEKPLCSAQFLTDGSLSSYSLFQLKHRLPAPRGVGVFEVTRSDLEDNTTEAKASSVIAEARKMRELSWCVNVVVLSDDPAFLASFAESSLRGRLLVWATRLLVVTRLPLQELRRLLASSWTFSMMNAMVINLEERSGQFRYRIYTHQPYNTPEGKLVHLATWAPEYGLYVKSGQRLFPEKFENFRGAEVGVTALPFQPYWIEEETTGQDGALRKTYTGSDGLLLRTIAEGLNFTFTPLPVSTWGEVTQRVVERRALMAVVHHVLLPQRKERYDYTYTYEQILFDFCMARPSLTPQWQSLYYPLADAVWACILAAVLFMAVVLYMARKNKKFSPWNVTEITLGSLLGQSVPLDRDTNGFRVSVASWLVFAFVVGTAYRGNLTAALTLPKYPDRPETIEQLVKAVDSVTMPSYGTEFQAFFLRSNSEVFRTLGGLMEIVPSAMDGLNGVATKRQSFMDGRRYLEHMIAEHFTDARGEAQLYVGRQSVLPGLAGWPVPHDAPYKPQLDRLMMRILEAGLYEKWSEDMLRRARAEARRRQKRKLQELRLDEEDVEAEESTRKTKPLTVVHLQGPLILLLLGLLLGGAVFVLEAFVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PX26</accession>
    <name>A0A3R7PX26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-type lectin 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001184">
        <property type="protein sequence ID" value="ROT79859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PX26"/>
    <dbReference type="OrthoDB" id="2142683at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050828">
        <property type="entry name" value="C-type_lectin/matrix_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45710">
        <property type="entry name" value="C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45710:SF26">
        <property type="entry name" value="RH26557P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018697715" evidence="1">
        <location>
            <begin position="39"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="96"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="339"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="469" mass="52631" checksum="65C8D3258F93B6CE" modified="2019-04-10" version="1">MRSKPPSASRASRPPLLCGKHLPMFAFLVMVSAARVSGTNLKEMRSAVAATQLILAQQAQLFKGVLNATDYDCYHQEVADHRTAMAKECPYPYSNFMGECFFISKAKLKWPDARNHCLDMSGDLAVPTKLYALKTHVIEEKGSRSTWVGGQGEEDGSGWHWVNGRPIDDAYWAAGFPVTDPKTRQCVELRSTSHPPLKNKLCSALLRPQSSREIIRRPLLHRRLPRGVCGLRRETTVPPSLPAHWDQYLRSVEIPRVMSGPLQLLVALAFAWAFAAALAIPIPEDDDLRSAVAVSKLVLAQQAVFFRELINATRERTNGCLPNVRSELSVSCPSPFASVMGECFYLSKIGLSWEQARTHCRGMGAELAVPRHLYGLKSYVVGENGPTGTWVGARESESEEPEATDIEAKNEEPRWQWVDDSEVDPEFLYSKLPNRRPNHKLCIELRKDRHPTLDFKICNTSQRFICQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PX44</accession>
    <name>A0A3R7PX44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001177">
        <property type="protein sequence ID" value="ROT79892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PX44"/>
    <dbReference type="STRING" id="6689.A0A3R7PX44"/>
    <dbReference type="OrthoDB" id="5322683at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="332"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="56483" checksum="2B78E72478A0E7E2" modified="2019-04-10" version="1">MEETTSKLAASEAKCAELEERLQQTTASCETLTQKIDELTAENDNLTQRVEDMEKEKEGTAKTIAMLEFNNEHNKDKVRNMELSNNDLKETIASLMKEKEELTRQLREGASGVIDQYIKEKDELEERLTKEKDEQLEKYVKEDKALREQLEGLMEIRLSYEKQIKQIEENNAAMHRKIGGVQTERDVALKEAAHTKSQKVDLEKKFDDLTKVKSTMEEEIITLKGTISNLEEKLSSQKKPAKEEELVKVKQNLREVKEKLTLAEVVSGEVEEQRQRVREVESKMAVMEEQHRQQIKTIALEAERQVAVKEQECQQTITSAYDQQDNETNSLVRQHREAIREAQEEAREKASALDSVVHEYQGKLKYEDQLADLTTQHEAHIKEVEATWKSRAEKMVRQREMQLQEEMDGLSQEWNKERRELERLTQVAAAAFRSGTDSVELLKKQVAAQRKELEEVKLNHGLGVALEEAAEFEYLKNILYQYMLGKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q042</accession>
    <name>A0A3R7Q042_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zonadhesin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003145">
        <property type="protein sequence ID" value="ROT65098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q042"/>
    <dbReference type="OrthoDB" id="6391207at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018662544" description="Zonadhesin" evidence="1">
        <location>
            <begin position="20"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="44146" checksum="579E374210961D74" modified="2019-04-10" version="1">MRAAQVLMVVLAAAGPAAAQLEFLNNLVGGGYLPPDNEPAGGYNCENAIQTTTIVDIQTQRVDQPITVDRTRTAQAQAVVTEVQAVTTTMVQTESRQVQVPVTQTYEQVAQAVQTRIAEVPFQPEPVVEQVTQTSVVATTQVNEKVDTSITQVTEPVQVTSTQVETAVTTAFETQTQQEQRVETAVFTPQPIVSTVVETQQDERTEVAQLPDVTSVVDTVVVQTEQSVRFVTPLPVVNTQIVTETQVDTQYQEVVQTEQAFATVENTRTEVVQVTDNRIDYVTSTVVRNEVVTQTSTLVEDRQQFETQYVEQVVTSTQVVDQLDERFVTSTAYVQATDYQTITGAADIREEVVTVTKDQVQVITQTVGNTVEQTVNQVVTAPCQQTQTGYNYNAPARPFTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1C6</accession>
    <name>A0A3R7Q1C6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000688">
        <property type="protein sequence ID" value="ROT83421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1C6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="458" mass="49620" checksum="6AED70C51C302D8B" modified="2019-04-10" version="1">MPVTGSNKKCAGIQGACGAPARPICGLVGFLNSGRAEGHLSPPGAMRSIDLLMLILQVGGSMPFRGRLPHEPLRRSRWLTAWCLLRAALYAGLHAATFVSSRAVFARSGVEVVARAMTHYVARILMQAAALLMLASSGKLAAVLSSLGALQARLRTHVLVSAKDPLVILILATFSLLYVAVAAKDIHDLYVEASSGEGAWVDRLPAIGSWVCGGFTMLSVPATLSLVVKYFTLALRSTVPPWAQLLLERGGPNGETRRLRTSASPSEVYKTSLLDLPDVASSQTQGAFPPTKPEMESFLSNVQDILIQTDEAFFLFTDYIGPVLLVWTLLTAAAFTFALYLLVDAALKGQALWEHCVIAVVVFLTFLLINVSADIVTQERRKCSWVYRKLSVHPALADLLKIRQILDHLDTPLQLNVAGFMVLGKPCVTTVRIRPFSVAITPLVLCRRVRKVIELSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2A6</accession>
    <name>A0A3R7Q2A6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Selenoprotein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015332</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the selenoprotein M/F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002914">
        <property type="protein sequence ID" value="ROT66637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2A6"/>
    <dbReference type="STRING" id="6689.A0A3R7Q2A6"/>
    <dbReference type="OrthoDB" id="25165at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.50">
        <property type="entry name" value="Sep15/SelM thioredoxin-like domain, active-site redox motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038219">
        <property type="entry name" value="Sep15/SelM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014912">
        <property type="entry name" value="Sep15_SelM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08806">
        <property type="entry name" value="Sep15_SelM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Selenoprotein F/M" evidence="3">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="79" mass="9242" checksum="61FAC52454550243" modified="2019-04-10" version="1">MEDMPLFHNADVKFIGGAPPELVLLNASNEEVERLPLSELNREECNMLMLKKGFYKKTKKDEEVPDQYREGPYKERVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q7V2</accession>
    <name>A0A3R7Q7V2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="7">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_010942</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01002388">
        <property type="protein sequence ID" value="ROT70764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q7V2"/>
    <dbReference type="SMR" id="A0A3R7Q7V2"/>
    <dbReference type="STRING" id="6689.A0A3R7Q7V2"/>
    <dbReference type="OrthoDB" id="363185at2759"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002055">
        <property type="term" value="F:adenine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000004">
        <property type="entry name" value="Adenine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002634">
        <property type="entry name" value="PRK02304.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002636">
        <property type="entry name" value="PRK02304.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF3">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="14">
        <location>
            <begin position="32"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00017366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="35056" checksum="C230654E63E07299" modified="2019-04-10" version="1">MDERVERIKNKITAYPDFPKPGILFRDIFSVLQTPLVFHDLMAVLEEKVKSVCPDVDIIMGLDSRGFLFGAPLALSLNKPFVPVRKRGKLPGELKQVSYTLEYGTDVFEAQASSIKQGQKVVIVDDLLATGGSMKAASELVKEMGGVVALCLVCIELADLKGRDKLKDPCFPFMSDLNVEFMKDISFLLGLKIEFLSAILSYLSDTHLPYSPGALLSYLPDTHLRYLVLLTCTCLTHLALSCPTYLTLTCPTHLALPCPTYLTLTCLTHLALSCPTYLTLTWRSLALTLMPYLPVALLPTYLTLALLTWRYLALLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QA51</accession>
    <name>A0A3R7QA51_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_020785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004168">
        <property type="protein sequence ID" value="ROT61433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QA51"/>
    <dbReference type="OrthoDB" id="6368705at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF26">
        <property type="entry name" value="RE23625P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00299">
        <property type="entry name" value="ACRYSTALLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="67"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="163"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="486"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="173"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="294"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="343"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="486"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="619" mass="68245" checksum="BAF615B9CA9C71EF" modified="2019-04-10" version="1">MASGKSLNVVQREGFFDDAFFKEAWEDFDRAVQTVLDKFDNRGLKVDSGSRSQCRDVYSKIRSSTIDEDLYASQAVQINEKDGKFQAVMDVKDFNPRELQVRAVDDRIVVEGSYQKVSEDGSSTSCKSFYKEFSLPAAADIDQVTTALSKDGVLTIKAPKKEGAAITQGPKTSNSSSSVQQSSSFSQQSDNNSTSSFKSSSSRTVVQSSSSFEGSSLDGFDSLPKEMREKLMFSDSGFGSTKTSTCTSPAPSEAGSESSRVSSTMEFDVNRGAAPVRSEVTFNVTSPSQPTPQPMYTQGPPGMQQQPQQAPQQLPQYHPQQTFQQPQPQMYQQPMFQQPPRPVFQQPPQQMPQQMPQHMSQQMPQQMPQQMPQQMPQQMPQQKPQQMAQQMPQQMPQQKPQQMAQQMPQQMPQQMPQQMPQQPSQSMYQQARPQPMAQAPTAGTGSGNQTSVSITEENGRRVMTSQTSNVVQENDGVMEHRETAAEITDKNSQAARREASTKMTRHEEDPEGKFKRSEAADAAEVSESCIQHMPDGSVMSVKKSSSSTSSVKQSFSSSMGGPGLFLESGNFPSGFGDLKNLMGRGHSLMSQMSTDSMASTMSVRLMLESSYVAAHQIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAE3</accession>
    <name>A0A3R7QAE3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008788</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002111">
        <property type="protein sequence ID" value="ROT72795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAE3"/>
    <dbReference type="STRING" id="6689.A0A3R7QAE3"/>
    <dbReference type="OrthoDB" id="27823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF3">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="268"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="353"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="56"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="417" mass="44849" checksum="B9CD3DCF447B141C" modified="2019-04-10" version="1" fragment="single">KSPHQQEQNGTSSKSVVGGLFGRVRPPPSRPKPSSAHNSMSVPSTPVTEAALIDFSSPPGSPTTRSGSDGLSVNSFGSESSSGNQSSGFDDSFDPFGSILDQNHFVPPKKVGVSSFYTGQFAGDNAQTQPSVADNQDPFEMLARRLDSVSSTPNQQSASASSQMQTNPMVLPHNSAQPSTQNMKSEQKANYRPTIIRTKAPVTSSHVESAGGTGNTNKNQQYPGAAEDICSIDWGAGSRPGGVNIIDQTIPEEPPPLPPRPEAEEEDQDRPYGIAEFDFEASQQDDLSFKSGDLIQLLYRMNDDWLFGRCGHKEGMFPQSFIKIVVPLAGEQAYPDSSASSSNTKTSSSETSNTSNVVTALYTFQAETSEDLTIMEGSRLCVTGRISEEWLYGECEGRVGQFPANFIDRIPQGLLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBV8</accession>
    <name>A0A3R7QBV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001952">
        <property type="protein sequence ID" value="ROT74016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBV8"/>
    <dbReference type="STRING" id="6689.A0A3R7QBV8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="41750" checksum="2632F10BF896CFE9" modified="2019-04-10" version="1">MRRQYLHRPLKHRLKPLLLLRNSPSSLLPSIHLPSQSLLPYSPPPPLLLFPPLFIPLPPPHLSFFSPPPHPLSPSPPSTLLIHPSSPPPTYLPLPPFPSSLFPPLPSSFSPLPSIPLRLPPSTSHPSSPFALPSTSSSSLILCNLPINLPHSFSLFRNIFPSLPSSLSSISYSFHPFLFFLPRLFSLPSIPSLKLSPTNPYTTLSLSPQPHLPFTPSPLRDILPSTSIPYSSTPPFYSLSLPPFIPHALVIRHQPPIFILLLTLPHRQSPPPSSAQPPSCPLITHFPPYLSSLPPSPITHTPTTSPQPPIPSSPPPPFLPSPPLPYHTSLHSSLSPPPFPPPFPSLPPLHPHLFLHLSPSSPIHPPPPHHPPHHFPPHPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QDD0</accession>
    <name>A0A3R7QDD0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003348">
        <property type="protein sequence ID" value="ROT63975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QDD0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="41888" checksum="C21C0EA42B832274" modified="2019-04-10" version="1">MNNLGGSGARAGPLPNAAPLEPPAKGTRGFVLGSSRFGRTYSGNPGCALAPPSTAEPPALPPNRSPGGTGKGAGSEHAGLAGWFGRLRGSASPAFRHVNPTLGPNGWQAGMAGAGARGRTGHPRQQRRKREQTLHVFRERPDAGPASLQSLCWVSHLCVSRLPLNEASKGRRTCALRKRVAHGAKHPAHKTGLGAVAHLVGPGDPGGADKDFWVRPPPSPGGGGEEAGEPCREPPVDGTEPSQPASQRDREMEEQRRAARLHGRAPSQTSPPNWGMGGRAGPDGGRSSSSSGSRRGSPPAARSRGSPPVVVGAALSPHDRGQGPLGPGGHGRQPLRRPRQPGPPKACPAFGDGSRKGRGRQNNIRLQTPRRTPHAMGPWPQLALQGSAPEASKQASTNGSRQEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFH8</accession>
    <name>A0A3R7QFH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein stoned-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003031">
        <property type="protein sequence ID" value="ROT65829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFH8"/>
    <dbReference type="STRING" id="6689.A0A3R7QFH8"/>
    <dbReference type="OrthoDB" id="6363808at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="748"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="838"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="932"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="880"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1127"/>
            <end position="1146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1232" mass="133404" checksum="FA21C6EF653B9206" modified="2019-04-10" version="1">MPVFFLLLQGLSLDREEEVQQEQAPQEEPGAENGGTASNSEEKAAPSGDKQDWRNFFAATDTVLKKTSDNLQHIKEASYFQKKEEKPAEPSAAAVPSAAAATAAPAGPPSATGKRWVDLESGGIDDETEVEGEEEAPKEEEPQDKKEPEAEPAPLQFIEDLPDVDVDDFAEVFDTTYVDNVESGEVKLHYIPDSPTTDYANEPDPFDTSVVDKVLHAEEPEPKKPQQTQKEPEKKKKKLVSLGCAVDVLTGKLQTPEKTPVNTTVDSKKRRVIPQEINLLADFTENGDAVAEEGETAEKEESEQKPEEKNLLDEILCVGDGEGQLPELGAVLGTTPRAVSPALPTEGEEGESDVKVNEGIEGENKEVDLSEFLESSGDDQDSKETKQENGKDLDLKDLVAEFDIIDKSEVTNETLIPTEPDPIEDEFDAEFAFLAAESVAKSKEKEFEELEDDPFDTSVAAQVLGPEGNADEKDPFDVSFVDGVVIEDTTQKVRPAKPPPPRPTLPKVQKEEPEEEVDPFDTSIAEKHLPVDHLASPDADASLPEALQPQAESDITKSASFDPFDTSIAESFGKTELKVLESELLSAGQPGTLSKSDSDFDFNPREEEEPKAAPCLLTSSEIEDTSAPVLAPSQDALADDFDPFDTSIAAKVEIQTLEAEFLTQPANNQEKSEEASATPKKKQPPPRPAPAPGHLLATTPTDNNPTLLPSSANEKSSADDNFDPFDTSIAESFGKTELKALENELLSSQNTAQEVKQVPGEKKPEDRALDLPIKPLRPPSPRCLLAATPLDENPTLQPVLQPSADAPPSVADDFDPFDTSIADQFGKTELKVLESELLVSGSSEKVAEDNSFDPRAVEAPAKPSRPSRPPSPARPQCLLTASPSPTGAPPSLELLAPTETKPNAPEADFDPFDTSIADKFGKTELKYFESELLDTAPASGPDPFDEFDPRAEETKSKVPQRPPKPTRPPVPPAPCLLATTPTDISAPLQPCIEPSQEPKEAATAEEEFDPFDTSIADKLGRTEIKFLEESLLSKEESQVEAKPQAFVPRVENTTTAALPEASEAPSVTADHFLSSSPTEDLRPTLQPTSSVTEESAKEFDPFDTSIADQFGKAELKTLESELLTDSGVKRNLSDDEFDPRQEEAKAPKRPPLPPQKPATPVNLLDSTDDHNLPDQPIQVLQAQSAKSPEIGDDFDPFDTSIAADIGPSKAELKYLETELLSATKDPFDTSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QU10</accession>
    <name>A0A3R7QU10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001399">
        <property type="protein sequence ID" value="ROT78331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QU10"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="607" mass="66406" checksum="73655134CC4539FF" modified="2019-04-10" version="1">MWCQVETDLQLPQVEVAPLLPVEVAPLLPVEAAPLLPVEVAPLLPVEVAQLLLVEVAPLLLVDGGQVEVAPLLVEVAPLLLVEVAPPLLVEVAPLLLVEVGSAPLLLEAAPLLPVEAAPLLPVEWHYSSQWKWHHSTWWKWHHSLVEAAHSSRHHWWKWHHSSRWTTPPVEAAPLSRWKWHHSSRWRRYHSRWRRHHSSGGGAPLLRWRRHHSSRWTLLPVEAALLPVEAAPLLPVEAAHSSGEAAPLLRPPLLPVEAPLLPVEATTPPVEAPPLLPVEAAPLLPVEAPPLLPVEPHHSPGGGPTTPPGGPTTPPGGGPTTPPGPRQYESRTSTRSTTPPVEVEVLPRPVEAGGGPPPGGGPPLLPVEAPPLLPVESSPVEVPPLLPVETPLLLPVEVPPLGRQYESRTSTRPHYSSGGGPTTPPGGGPPLLPVRPTTPPGGGPTTPPGGGPTTPPGGGPTTPPVEVHHSSRPHYSWWRPPPLLPVEVPPLLRWRPPLLPVEAPPLLPVEAPPLSRWRSTTPPGGAPPSSRQYESRTSTRPGWRSHHSSRWRSHHSSRWRPHHSSRWRPHHSSRWRPHHSSRWRSHHSSRWRPHHSSRQYESRTSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SHK7</accession>
    <name>A0A3R7SHK7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-acetyl-ADP-ribose deacetylase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004091">
        <property type="protein sequence ID" value="ROT61583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SHK7"/>
    <dbReference type="STRING" id="6689.A0A3R7SHK7"/>
    <dbReference type="OrthoDB" id="2155246at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140291">
        <property type="term" value="P:peptidyl-glutamate ADP-deribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050892">
        <property type="entry name" value="ADP-ribose_metab_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12521:SF0">
        <property type="entry name" value="ADP-RIBOSE GLYCOHYDROLASE OARD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12521">
        <property type="entry name" value="PROTEIN C6ORF130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="68" mass="7900" checksum="F46C99100202949F" modified="2019-04-10" version="1" fragment="single">ERYWHKPTYLSLRSSLQAMKRHALQHNVAAIAMPRIGCGLDGLVWDRVREILTDVYKDTDIKISVYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYS7</accession>
    <name>A0A3R7SYS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic phospholipase A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024664</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000871">
        <property type="protein sequence ID" value="ROT82168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYS7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="43560" checksum="9AC4DDCBC14548FA" modified="2019-04-10" version="1">MTSERKPKLSLLMRPPDRRRSTSCMWDSHLSHHPLSLPLSTPQGFPPSFATSGGFLREIRCGPSAAAGARVPHQHTRQTSGPRQCSSHLSRSSSLSPAIIPRCILSVRSFSLSPSPSHHFVSRSRLNPLSLPRFFPFLSLTPRLVFSLSLSALVTPLISPHMRSCSHPAPPLVNRVFARSRFPLLRLRIACLLVLLCPLLPSRQLGVSVARYGTGRRPAGGRSLSRLFSPLGSPLAIRPPLPMSSSLPSSFLPLRLGPNLLSPLPPSSLSSYPLSCPLPSSPPIPAPFPRVRGAPFHLFLSSSEPAFLSSNYIPPRLEMYRQAVNSGSGLFQVLVVDHHLPTTRRRILVILHTNETCRYPPPPRYRARRPHANPAPASRPPLPRPALSRSPPAQRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZY7</accession>
    <name>A0A3R7SZY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative mitochondrial amidoxime-reducing component 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_023307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000675">
        <property type="protein sequence ID" value="ROT83511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZY7"/>
    <dbReference type="STRING" id="6689.A0A3R7SZY7"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="MOSC" evidence="4">
        <location>
            <begin position="186"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="318"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT83511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="607" mass="67853" checksum="420803025A0975B1" modified="2019-04-10" version="1">MDIPRSSIAVTLLAAVAVTLVFKFWSSWRRPRAPRIMRPRVKNLEELKDRSWQLVGRVSKVYLYPIKSCAGICLASAQATELGLSTGTIRDRSLIIMNEKGVMVTGRMIPATVKIQASVEDGVLTLEFPGAPTFSVQLSQVEEKNIQKTTRVWDDTVPGLDCGDEAASWLKEVLGRKCRLLYHGSIPSPRNTDLGEEYPLLRDDDNSLYADLTGYMLMTRESIGDLETRVKSHLPPQNFRPNILVEGTKAPYDEDLWEYIRIGNTLFRNVKPCSRCIFTTIDYQTGKKDSNMEPLRTLRSYRCVGGDNSPHFGINLGVDITGTINEGDARKQEEEREESPVRAPLPLDIAHALEELRIETPLPQPSADESGSSEGSVDAAPPACQPVSAEQWSDVSKAPHETRSQPLSARRSPEFAREFEILQHLGGAGGAPLPLSLTQKPLSFLMSYKGPRTLDAALWDMAWNGEEVLQTCHNVCLRVSEIHKMGYVHNDLKINNLILDEDLDVAVIDLGNASEIGKTFCYGGSRCFWLAPEMYTRHPVCVKSDIFSVGIIMSEIYVKTRIGHGFPELLEEIRSEDPEKRPSLEAIMDRLKQIRDAWSKRGQASNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFS0</accession>
    <name>A0A423SFS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative relaxin receptor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_019100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003504">
        <property type="protein sequence ID" value="ROT63021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFS0"/>
    <dbReference type="STRING" id="6689.A0A423SFS0"/>
    <dbReference type="OrthoDB" id="6372394at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009755">
        <property type="term" value="P:hormone-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24372:SF80">
        <property type="entry name" value="FI21465P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24372">
        <property type="entry name" value="GLYCOPROTEIN HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="45402" checksum="60863EB4B652D904" modified="2019-05-08" version="1">MTVILGAYAGLFFNIMVTRTSTPLSGGESKFALRFFFIVVTNCVCWLPIACVKAAALANIEVHSGVYAWLVVLVLPINSAINPILYTFSTSKFQSQVATLRTVFRMARNRQDSATDTDVLRYSSSRSWGSAAQCNVSHAHLPPLHVHNGSQNGSVVLIREKIDRRASAYGFCQRRSLGNNSYFFKDPLAKDAPSSNGVVSPEKDLNPGRHLTLSAKVSQARSSSPGERATDVSASPCSRGRLSLFKLELGRTPTPPSPESNRRDAKGEHTPSEGQEYKDICLEAHLSSHETPRPREITSPSESSSKVKGAPIYVGCCATSSSDNQNADVLRLNLTLCYNSDSTQLPLRTSSSLGVRRNSDSEYPLPSSSGKTTSVTHTVPETNQTPWHFPFPAATSLAPHPRRSSWSEFSSSVSASCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFU7</accession>
    <name>A0A423SFU7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Cytoplasmic dynein 2 heavy chain 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_019029</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003494">
        <property type="protein sequence ID" value="ROT63098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SFU7"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000006">
        <property type="entry name" value="cytoplasmic dynein 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000005">
        <property type="entry name" value="cytoplasmic dynein 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000706">
        <property type="entry name" value="Cytoplasmic dynein 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001810">
        <property type="entry name" value="Cytoplasmic dynein 2 heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000071">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049400">
        <property type="entry name" value="DYNC2H1_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF22">
        <property type="entry name" value="DYNEIN CYTOPLASMIC 2 HEAVY CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21264">
        <property type="entry name" value="DYNC2H1_AAA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="12 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="11" id="KW-0243">Dynein</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="15" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="1435"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="1729"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="20">
        <location>
            <begin position="2037"/>
            <end position="2185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="2575"/>
            <end position="2641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="2750"/>
            <end position="2840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT63098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2886" mass="329107" checksum="7FB6EDD9DB56FC05" modified="2019-05-08" version="1">METTDVRKNFILTTTGNYFSVPLSEPSLNALVDDPSLNNFLDSGSCQLLGAQLMPDEGRIIFNTKDSEWSGTLDPRLQSLVTELSEGLGSMLRKQSSVGASDKGATSSHLAGILNVKDETQYWAEIANNPKNRDEKEMAQGFYNCLDPIAKEFSGLDAVSLLDAEDILENTHNLLDELWRLDYPQSRMEHLLDIIANQITRYVQLTRLLSISEQEELKTADSFKPFAGLKPVQYNPYTEPLWQAAVRQFENSLKPAEQRIAGKTADALLNDLNGYDDLKRNIGEFCEELDDYHNDQFDSWSREMLQRIESEELSLATDSPVLSFSSSRLLRVNYNPRLVGLVREVSQLSILGHKIHPDIIKTAKLAQKFMKQAKSLEEIANFHNTIGDQMIPSQRAMMLEAALALSGLVQEQNNITWSNTAELDSYIGRLKAATQRLARENKQLAQCHLMVKERVLQLMNTDLLRHQPKWKELLKEMRSIMHQLDEKGFSDQKSWCSHWDRQLYKALEHQYQLGIEALNQHLPEFKVELTYRQQRLQFRPPMEEIRMKYYGQLKRFLAIPHHFKGVSEVNDHPVFPIIVDRNAHRFTQLFQRAEELFERLEKVKERFVDLCALGSCDIEQLVGKHCQIAEDWDRNFRASKAKGQEIGKLPSTEEKIDCFSISFQPLRVELEIMNRRYWDILVQSLHNAIIEDINAIEKFTASAIEVLKKQPQTVEEIAEASNKHAQYMAETEEMVERFNEAESKNKTLASWTKERVDQVSRVTMQWDNYKTLMDNHEQIVSKQIEAIKANLQSQTNNFNNEVEDFGLRWKQLQPKEDQLEGDSERIQAAITLVREKRFEWDQLMETRDSIRKDYEHFGMGEPYFPMIDEIEESLKQHEQVWGLFDEFNSSMEEFSKEEWIVFRSKTYRFEEFLSNWNDKLRSSGETTVVTVRLIHELEKYRAMLPVLKYVRGEVFSEKHWIEMYSILGIPTNVTIDKLTFGHFLKVRDEMINQNDVLKEMNAKAAGEVVIRQALGELDVWEVDARLTLIPHSDSRNNEIMLIKEWKDVINKVGDHQSLLQSLKDSPYFGGFADRARMWEQRLADLDEYLTNLNQIQRKWVYLEPIFGRGALPNEQGRFRRVDDDFKAIMADVARDNKVVSLCKINGMRNTLTTLLDQLARCQKSLNEYLEEKRSAFPRFYFIGDDDLLEILGQATNPEVIQAHLKKLFAGIHNVRFDEENSHIIAMRSLEGEDVPLKRPVQISNEVEDWLYRLSEEMKMTLRQLLSECLEEARSEAGMDPLRYPSQILCLADAILFTERCEESVKEGSLTSYQKELEAKLESYTGVDLSSDGTPEGKADSLVLELKLKALILDTIHNIDVVQILLQANTTSLSDWPWQKQLRFYVGDGGSAFMRMVDAQFDYTYEYQGNAPKLVHTPLTDKCYLTLTQGMHMGLGGNPYGPAGTGKTESVKALGNLFGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQAALKSQASSTMLLEKEVPVDPNSGIFITLNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNELIAEVILFSEGFKEAKSLGRKLVAIFTLSKELLTPQQHYDWGLRALKTVLKGSGNLLQSYRKSLSDEEKESGISLTVESELVVQALRLNTLSKLTFSDSSRFDDLVKDVFPDVKFRGVGYEDLASILQEVFTEMGLIPNDRQIKKALELYEQLQQRMGVVIVGPSGSGKTTLWQTLRQALLRMEQQVKKYVMNPKAMPRQQLLGHIDHDTREWSDGVLTASARQVVKEPTEVTSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSSASPATISRMGMIFLSDEDTNIQAVVSAWLSSQEESTRKYLEPYIEEHFFKALEWVLRAGEAQVETTLVGWVLNGLSHLPGVTSKVHFALALVRGLGGNLPESIRADFAREVYSWVGEHIPDQRKPLNIYYDSARDRLESYSSESVENIASDTAEMPLILTSDALCSLDYFSPWLEMETQQPFILVGPEGCGKSLLLHHCFSKLRSTQATMIHCSAYTAPQHILQKLAQMCMVISTNTGRVYRPKDCERLIVYLKDLNLPKPDKWGTCQLITFLQQVVTYNGFYDQNLEWVGLEGVQIVASMTSGSALGRHKLSTRFTSIVRIASIGYPERDQLVNVYAAYLRSVLNEVAPDHKVWGSQTKVQQLATSMVNVYHNLRDAFSVDDYSHYLFTPRDLTRWVLGLLRYKIDAEDEALQPLLEVAPGAPLPIHGYKLGFMNNEDWTHVVERAVLQFSREKLELDLLIFPEVLESMARVDRVLTSPGGSLLMAGRSGVGRRTAVSVIAYLHGIKVVSPAMTLGYDIKNFKNDLKQVMQAAGVDGEQVLLLLEDHNLVSSAILEVINSLLMAGEIPGLYTSEELDPLLMPLRDEAAHEGFRGSQYAYFASRVRKNLHIALIMDSSNQDFTLQCESNPALYKQCAVLWMDGWSRETMVQIPSMLLKESELDSKDSVEFQQTFLAIHESLPLHLSTPRRYLVLLNTYRSIYTTKKEGVLHRQGHLKAGVAKLNEAQEVVSKLKAEATEQEVRLAEKQEEANRALQLITNTMKNANDQKVQMESLKEQTLKENQIIAERSLRAPPEVIRDILEGVLRLMGIQDTSWNSMKTFLAKRGVKEEIRNYDPRSVAPESRKAVEKLLRERADSFDPVVAKRASTAAVPLTAWVKANVKFSYVLEKVKPLEQEQNKLERNLTRAEAQIGELSAGLDEVDKEVAVLREKLNRSTKEAVEVEFHLNKAKETMSAAESLVTKLEGEYKRWSQQVSELDSDVQDLPREAVLAAAFITYLSEAPEDTRKATLMHWSKMLHVEDFDLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SG13</accession>
    <name>A0A423SG13_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_018920</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003476">
        <property type="protein sequence ID" value="ROT63166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SG13"/>
    <dbReference type="STRING" id="6689.A0A423SG13"/>
    <dbReference type="OrthoDB" id="2270193at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd15525">
        <property type="entry name" value="PHD_UHRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20387">
        <property type="entry name" value="Tudor_UHRF_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20388">
        <property type="entry name" value="Tudor_UHRF_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021991">
        <property type="entry name" value="TTD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF45">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12148">
        <property type="entry name" value="TTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="15">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="281"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="YDG" evidence="16">
        <location>
            <begin position="401"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="452"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT63166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="61094" checksum="28CD3A75062A96C8" modified="2019-05-08" version="1">MDGSQTAIITISKLTTVEDFRQMILEKMNVTAERQRLFYRGKQMENGHTLFDYNININDVIQLMVKPVLSEINSNVQAKASSAKRDGEQADKENTKTDSEVKGNADVRESEYYRVGDLIDAKSLYDGTWWEAKINKITVNPKVKEISEEDDGMLYHVTHEGFEDDVPEELLLKHIRPRAFQNVKLDDLCKGDLVMANYNLENPEERGHWYDCKVSKVMNSRTQKAVIATVFIGADSSPMDDCHVRFVDELFRIEKNIKLDERNGDMERRIIEGSPVKRKNAPNCATCKDNPKRKCKECGCHECGGKENPEKQLMCDECDLPYHIYCLTPPMETIPDVDEWFCPLCKNDDSEIVKAGEKLKESKKKAKMASAKSNTSRDWGKGFACAGRQKVCTIVPQNHFGVVPGVEVGTMWKFRLQASEAGIHRPHVAGIHGRENEGAYSIVLSGGYEDDEDNGESFTYTGSGGRDLSGNKRTAEQSSDQLLTRMNRALALNCNVPINKNGAEAKDWQKGNLYALFGTAKGESIQNMLQKKEIGMMVFIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH83</accession>
    <name>A0A423SH83_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative methyl-CpG-binding domain protein 5 isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003419">
        <property type="protein sequence ID" value="ROT63576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH83"/>
    <dbReference type="STRING" id="6689.A0A423SH83"/>
    <dbReference type="OrthoDB" id="6375773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="565" mass="59306" checksum="7C4809E6A516F851" modified="2019-05-08" version="1">MTSPTAPLSPAPPSPLPPPRLSRRESAAPAPDRKLELVRNRSKSHICPAKGTSGLVVVGRSRSLARNFCRGGSQGGEWRDGDWALALTESVGADGGLWAGIGVGLSGQGRGEFALRGSGGPTACRRAQNRVGRSVSREGMVGFWFNLSSLARWTEEAEAESRGAGHPASDPHVHPPAPRPGRVPHAAGNACADAKGSPHAHADAQRCPYAHTDAVRAPNPHADAQAALSRPNAPRNAHPNAADATGWGMMGAIPRMAGGGGYGPVGGVMNVPQGCNHHYHQQHGPAQHCTPTSHACCDNHHRFPVNMPSNMNNMGPNMAMGPGIRPGIGPGFGEMPQQPQPPPPNMMGPGSHMMPGMRGVAPHPPGFMNANMMCRMPGPGMMPPRVLPPGNMANPQGGTERPSAPATFWEEGEKRRKTGGRAKKRFKGVLERASPCPNVDVRNIHGEHPRPNMSGQGGPGPPHSGPSFMDDPSGYLAQQTALLNNTMAGGGMGHHDNTLCPSHTFNTHKCNRSPHTNPNLATNQYLNSNKSTDLIQGGLSEKPTCCSRKDSKSSRGCQTVPGSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH96</accession>
    <name>A0A423SH96_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein lifeguard 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018555</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003424">
        <property type="protein sequence ID" value="ROT63554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH96"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10428">
        <property type="entry name" value="LFG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF47">
        <property type="entry name" value="TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="233" mass="25985" checksum="2057622578879646" modified="2019-05-08" version="1">MEDIEAEDATFAFSEKSIRMGFIRKVYAILCTQLLITFGLVAVFVWVPAVNDYALKNQWMLWVAIGLTFTMVIALSCCGNLRRKSPHNYIALFVFTISEAYLLGVVSASYQGKEVAIAIVATAVVTLVLTLFAFQTKYDFTMMGGFVLVSLTVLLIFGILAAIWSNQIVNMVYACLGVLLFSFYLVFDTQLIIGGNHKFAYSPEEYVFAALNLYLDIINLFMYILAIIGGSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLY4</accession>
    <name>A0A423SLY4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016856</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003125">
        <property type="protein sequence ID" value="ROT65181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLY4"/>
    <dbReference type="STRING" id="6689.A0A423SLY4"/>
    <dbReference type="OrthoDB" id="6362376at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046488">
        <property type="term" value="P:phosphatidylinositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032228">
        <property type="term" value="P:regulation of synaptic transmission, GABAergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF196">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="90"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="282"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="612"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="705" mass="77058" checksum="4E278C0AAB7F58A8" modified="2019-05-08" version="1">MSSLSESCAAKLAHTCPEELVNHNKNFLTRVYPNSSRVDSSNYNPQDFWNSGCQLVALNFQTPGQMMDVYEGKFRANGGCGYLIKPAVMREHISVFSANSRETIPGVAPQLLKIKIISGQCLPKPRGSTATKASFIDPYVVIQVFGIPADCTVVLSPEAVPSPIYSPPSTLYYSSPPLARPSIRHPSLPVCPEPPLPSCARQLLPVKEDSGELRQEGAALAKTRTVSNDSSFPIFDESFEFLINLPELAIVRFVVLDDEFIGDDFVGQCTVPFDLHPDGSCAGGGPLAPSPALGPPSQAPDALAPSRIPPRPPAVEHGRPMDNASLFVHVSISNRRGGGKPQRVKGRRADKVQADIKPVGLRAADDIFKEALASLTEAEFEENKVEQAWTDLQDECGLEHTANMKQCLKVTISRYMAHPDTNQLSIREENGIPFLRSSCPGPLPSHLHKLEVALEKVLLEIHHFLTHGDALRTSLESQLKPALGMYDNLESLLSSHGVKGKKANKATENFAWNVRIIRGQLDRLEALKKKCKMALEQVTFSISSCNVAVIHMSHVHVTQMLSLSKDDACHEGTRGRRPAVREVESTKATLDSLNTRERSPSVRERPRLTLANRHNTTENLTTYGSLGRSPTTPSGECKPKSILKKSNSNLESSSIGYVSEDYLMTPSSSSTVVGEDEDAANLLKPPLLHSFSYTPGFSYEQNTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN99</accession>
    <name>A0A423SN99_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lacunin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016398</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003065">
        <property type="protein sequence ID" value="ROT65629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN99"/>
    <dbReference type="OrthoDB" id="5950222at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048019">
        <property type="term" value="F:receptor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050431">
        <property type="term" value="F:transforming growth factor beta binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22639">
        <property type="entry name" value="Kunitz_papilin_lacunin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45938">
        <property type="entry name" value="ACP24A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45938:SF11">
        <property type="entry name" value="WAP, KAZAL, IMMUNOGLOBULIN, KUNITZ AND NTR DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="8">
        <location>
            <begin position="278"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="8">
        <location>
            <begin position="337"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="43734" checksum="F896EFC8652C622E" modified="2019-05-08" version="1">MHPFSHFPPFCLPFSQFPPFYLPFYHFYHPSISLLSPFLPFVSSLPSISLISPSLLSPLSLLSPFYHPSITLLSPFYLPFITLLSPFSPFISPLYLPFITLLSPFITFYLFITLLSYLPLSLSPLSLFSPFFSLPGCGCEFSAYGCCPDNETVARGPNNEGCGCQYTPHGCCPDNHTPAGSANKEEGCPCHSFEFGCCSDGVGIARGPNGEGCGCQYSPYACCPDGKTPASGPDLEVACGCESSRFGCCPDGVTKAAGRFFEGCEAEEAEVEVPGEVCGHAKDRGPCGNFTVKWYFDMDYGGCSRFWFGGCEGNLNRFASQEECAAACVEPEGRESCRLPRVSGPCTGSIPSWYHDPASGTCKPFVYGGCLGNNNRFQDKESCEEKCVIPEKTGKLRDSGEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNX7</accession>
    <name>A0A423SNX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">B-cell lymphoma/leukemia 11B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_016178</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003028">
        <property type="protein sequence ID" value="ROT65844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNX7"/>
    <dbReference type="STRING" id="6689.A0A423SNX7"/>
    <dbReference type="OrthoDB" id="10046198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000046">
        <property type="entry name" value="Putative B-cell lymphoma/leukemia 11A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000739">
        <property type="entry name" value="Zgc:171418 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001175">
        <property type="entry name" value="Zinc finger, C2H2 type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051497">
        <property type="entry name" value="Dev/Hematopoietic_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45993">
        <property type="entry name" value="B-CELL LYMPHOMA/LEUKEMIA 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45993:SF6">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="622"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="650"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="680"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="102"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="245"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="368"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="596"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="386"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT65844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="773" mass="82898" checksum="BE85BC740703B170" modified="2019-05-08" version="1">MRKKNGGKISLSPSLAAPPRMAWQQPVASHGTAGRLAGTCPVSSCRPARFQPVPRLCLKGSKPARYVCGTCGAVLGSAWSLVQHVQSSHGIIIYQEAPGATPLSTPSTPPGLPRPSHSSPLASVSSTAPTASAPHPPPLQLLDPAKVDLSKVDITKVDLSKVDLSKIVPPVTSGATPLPPHPPVTAPLLDPTHPFNLLRMPLGDARAPFPPGLAPPFVRPGHDFRMDQLLQEGLRLNPGLLPPHFERPPFLDPGLAPSAAGGHHQPHQLHLAAEAPADAPSPPFSSPNAPTPSSLAPSQTPTSTRCDALAQQHERRFKCITCCKCFRWESNLAIHQRLHTGEKDIRCPRCPETLPTPQKLRLHMKAHRKNCNTESTSPDSSRPQTEDDEDNPSVCDSNDEDDDIVEEEAEDDEPEDLSTTSKSTGSGPAPQSVSSSTTDNNNKSRSDQQKSVVGELMDKFGLANISAYSEAYHQALKESGRLPPPHIGKDGEKIHTNGMEKLKLRDDLTKGLMGSQPSLDLAHQTLLGAFDNPYEAQKRLAAAQRDSSLYAGLWLPNLAGTGTTPRDLFPGLPPSEGNFLQRKILDGSVKAGELSLAKPGTSSAPNTPISLVPPSKKEKRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCDLCSYACAQSSKLTRHMKTHGRIGKDVYRCRFCDMPFSVASTLEKHMRKCVVNQNKKGLFPPLSGSHDGLDSYKGLHFTPVISDDSSKSGGLFSPHFTAAAAANTSNDDTGDSSNLSGPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQ41</accession>
    <name>A0A423SQ41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative transcription elongation factor SPT4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_015690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002962">
        <property type="protein sequence ID" value="ROT66288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQ41"/>
    <dbReference type="STRING" id="6689.A0A423SQ41"/>
    <dbReference type="OrthoDB" id="248751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07973">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009287">
        <property type="entry name" value="Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038510">
        <property type="entry name" value="Spt4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882">
        <property type="entry name" value="SUPPRESSOR OF TY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Spt4/RpoE2 zinc finger" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT66288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="75" mass="8796" checksum="4D9270974EA79B04" modified="2019-05-08" version="1">MKNNRDQVYDCTSSNFDGFIALMSPEDSWVAKWQRINRCCRGMYAISITGRLPASVIREMKSRGIKYRQRDMTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SR00</accession>
    <name>A0A423SR00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002911">
        <property type="protein sequence ID" value="ROT66655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SR00"/>
    <dbReference type="STRING" id="6689.A0A423SR00"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051266">
        <property type="entry name" value="CLCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041940">
        <property type="entry name" value="choice_anch_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10579:SF177">
        <property type="entry name" value="CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 4-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019134653" description="VWFA domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="322"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="928" mass="99568" checksum="F4AD8279F59D8CD8" modified="2019-05-08" version="1">MRRQTSKSLAALLAMATLAALRQEATATHASVSLSSNGYEGTVVAISPSVDEIYANDVIDSIKKTIGEASEVLFKATRQRAFFRDVKILLPKTWTRTPYDQVAVTENFQDSDIRVDKSNAVYGNQPYTDQPGGCGDPGRFIHLTPDYLTDDTEAAKWGPRDKTFVHEWARLRWGVFDEIGYPDDPKYPLFYLDFSNYPFAIKPNYCANEELTGSQMDNTTGDLCSELNGLPTATCRFDPDANQVANSSLMSYYYLSSIEEFCDSTTRTPHVADAPNRHNDKCARSSVWDVMEAHADFTGGANPPVSSSTPTRFTVVRQEEAKFALVLDYSGSMISYSRIQKLQMAARRWILHEVSMGSSVAIIKFTSTATLVAGLTAISNDATRQSLAQRIDSAAGGGTCIGCGLQMAIGSVLNGQKNAVILLITDGQENPTPPRMSDVMNDVIASGARVVTIAFGESADPKLEELAKNTNGKTFTVKDTDNGNQLNDAFLGALTYQPGEVLAETFIKIYETDYQGASRVFTEQFTVDASLGRDLTFKLETNTASHVTSRPHLLRPDGTQIDSATFDSTSNTYTITVAMAETGQWSYSVGLSGSTTNSISVSVSAKARTPNVEPIYTSAWASAGSGSVNAATNPVIIYAEVKQGNSPVVGARVKALISETSSAGAPIELELYDNGNGGDAQAGDGTYSGYLTTYSSVGRYSVKAQVWNDGSALVNNGFTTSRKKRSHPAARNIRSVSAHPLDKTPYCCGSVVPLDPATATPTGNFTRVAPGGSFQVTVIPTGDSFAPSRVTDLQMTLGKTNLTLTWTATGDDFDTGIVTGYVIRLAHNVTYLHEVNFDNSNTTILLSVADCANLTSLLVEAGQKVTLDLTLKEEVKTDTPYLVALRAVDDAGNESLVSNIAAALVPTPPPPPPPADKKGLSLTLIVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWS7</accession>
    <name>A0A423SWS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="21">DNA repair protein RAD50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_013266</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002655">
        <property type="protein sequence ID" value="ROT68583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWS7"/>
    <dbReference type="STRING" id="6689.A0A423SWS7"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013134">
        <property type="entry name" value="Zn_hook_RAD50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04423">
        <property type="entry name" value="Rad50_zn_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75712">
        <property type="entry name" value="Rad50 coiled-coil Zn hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51131">
        <property type="entry name" value="ZN_HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="13 19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16" id="KW-0469">Meiosis</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc-hook" evidence="20">
        <location>
            <begin position="632"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="292"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="389"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="734"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="676"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="679"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT68583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="770" mass="89160" checksum="2CA223C5CA311AA6" modified="2019-05-08" version="1">MGIRSFGPEEPRKIQFFSPLTLILGQNGCGKTTIIESLKYITTGDAPPGCGKGASFVHDPKLAKEVTVRGQIKLMLKDTKGATLVTTRSLEATQKLKKIECKTIDATLQRRRPDGSTDAISSKCADFEAEISNALGVSKPILNNVIFCHQEESNWPLDEGKKVKEKFDAIFNATKYIKCLDTIRKLRAEMKTKVKNMHEVIESLKKWRDEANRKRVDLKESCEQQNKIKVQKSKLKEELEPIRERLKEICDLEENVGRLNGELIGEKHKLEALRQSQADLRATLSEQLDCSDEELYHMIQDFQKNLESMEEEQEKVMSRMQSIQREKEKNQTEISRTERLRGEYEAAYKTQQDYIKERNRQMSSITKEFSFAEFMGVEDFSEQQAQCLLSILLKLVEEERKKIAEKKEEYERKEEAVQKEIDGLRTSEAALDHDIKTKGKQLDETGKKIRQLKQALMRNESDLSDMDLDSLKVELTQVEDMIAKEESKVNMTELTAEIERAKKNKREGEHEVDEIKRVVAKMNRQANARSQYDIHMKEKKELENRIEFLKRKHADEFEHLLEAIPDDNIKNKVDACADSLRRRVTELRQEIEGLNKRRTHLSVSIKGQKQQQSRKEQEIRDLESKIDNICDGMNLDEALEKSKEVKDNLTRERGDLSSSITVLNRFTAKLRQRDCCPLCHRDFPSKDDVNQLIEELEGKVISIPGKLEQVKVKLDKQEKVHDQIIQLKPQRNLANSAKVELDKIRAQIEEEMKELAKVDSDLESQKKCWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZD0</accession>
    <name>A0A423SZD0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002549">
        <property type="protein sequence ID" value="ROT69577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZD0"/>
    <dbReference type="STRING" id="6689.A0A423SZD0"/>
    <dbReference type="OrthoDB" id="6333371at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="50"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="294" mass="31450" checksum="66D64F20C7B62A53" modified="2019-05-08" version="1">MLPPHTQLSLICVIGGSTYAPSAGSRRPPGGGAEGVLVHDVKVPQPGISGRSAQLECLWSAGVKGFYSVRWYKDGEQFYSFIPQNYPEVKVDHNLPGVTVYLSKSNEHIVTLRKIDLVSEGVYRCEVMSEAPTFQTSFASANLTVVEMPGAPQIVGMQDSYTVGETLRLNCTVPDSRPPARISFSVNGRLIHPGSGRITEYPRVDAGGPGHPYALSTTRSQLTLPLGERHVPAVTVECEAQVLSLTTHASHSAHVRPLSTAFSFFNAGSSHAPPPALSWRGVAAALSLLPLALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZX0</accession>
    <name>A0A423SZX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative dynein intermediate chain 2, ciliary</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012217</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002549">
        <property type="protein sequence ID" value="ROT69578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZX0"/>
    <dbReference type="STRING" id="6689.A0A423SZX0"/>
    <dbReference type="OrthoDB" id="6372332at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="361" mass="39421" checksum="5D55929E40582ABC" modified="2019-05-08" version="1">MLLESTCGASDARGMLCLFTLKNPGIPERVLQPPCGVTSVQFHPSRASVLAAGRVDGAVMVVDVRSPRAPRVITSTVVAGSHLQPVCQVRWVATDPGESLCFYSVSEDGRVSEWLVRPSALVHADILDFIASAENAKLSKEASKFILAGRATCIALNPSDKTDMLVGVDTGEVLQLKTSSTHALTRYPAHTGAVRDVAWNAHHSKVFASCSLDWTLKIWIRDCLSPLVTLDLGAPVASASWSPYSSSVVAAATDEGRVHVYDLFLRKCRPLCSQNLNQRRRLGLSCVAFNPFSPVVLVGGEKGYLMTLKLSPNLRRPYRDAKGAEEMRPTEIELCKMERIIATSKEWEKPGDEHMRFSAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0S0</accession>
    <name>A0A423T0S0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002476">
        <property type="protein sequence ID" value="ROT70065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0S0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="45417" checksum="D9C2D9690FD71391" modified="2019-05-08" version="1">MAGSRRYRYISNNCAVVVVRESRWQPYGGWPRCEARSAIERFECGDRVGKRGNQPGRYDEDDGRGTPSPRMTLIESTEGFMSSHWKLRLAYWGVGARVCVGAAPATLDLHAIATPPDFYCPGRHYFADRAFPSPASQLPSALSPGQSSAAPPRRVSGGRASPRPLRRGLLSDAAGPVRSPRRPDAFRFNAPPHDNGLVDSRCRPFPHPTVVSSLSPPSLLSPSAPHATTSLLTPSPLLSPTPSPLLPSVLPLPPLLHLSPFKDYHRLNTLINAPSLPLSLPSFLISPLLFPSCSNLFLFLFLPSSLPSSFFFPPSLSYLLHFLLLSPFLPSFLYFPLFSFLLTLSPSPTSAAALFCPNFPILFPWSSFPSSILEFIAKFCRRRLFSPHPLPPTLPPPSPPTPFPSLAPPPNPFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0Z2</accession>
    <name>A0A423T0Z2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002496">
        <property type="protein sequence ID" value="ROT69948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0Z2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT69948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1083" mass="118088" checksum="9F2B05309B6D7186" modified="2019-05-08" version="1">MWWKQVVAACGGVEASQYVVEASGGSMWSQYVVEASGSSMWSQYVVEASGGSMWSQYVVEASGGSMWSQYVVEASGGMWSQYVVEASGGSMWSQSSVVDVAACGVICGKQVVAACGVNMWWKQVAAAMWSQYVVEASGGSMWSQYVVEASGGSMWSQYVVEASGGSMWSQYVVEAMVEASGGSMWSQYVVEASGGSMWWKQVAAACGVNMWWKQVVAACGVNMWWKQVVAACGVNMWWKQVAAACGVNMWWKQVVAAASGSMWSQYVVEASGQHVESICGGSKCGVSGGKQVAAACGVNMCGSKWRQHVESICGGSKWRQHVESICGGSKWRQHVESICVEAVAAACGVNIGGSKWRSMWSQYVVEASGGSMWSQYVARQQWSQYVVEASNVESNSGGSRQQCGVNMWWKQVWQHVVKCVWKSSVKWLWCGMWSQYVWKQVVAACGVNMLVVKQVVAACGGSKCRQHVESICGGSMWSQYVVEASGGSMWSQNVVEASWWQHVESILVTVVSNVDVVAVWRQMWSQYVVEASSMWSVVEAKWGSMESICGAACGAICGGSNVEHVNMWWKPKWGSHVSYVVEASGGSMWDNMCGSKWCGQVVEASGGSMWSQYVVESKWVCQVKQVAAACGVNMWWKQSGGSMWSQYVVSMWSQYVVEASGGYASSMWKSICGAACEASGGSMWSQYVVKQVAAACGVNMWWKQVGSMCSQYVVEASGGSMWSQYVVEASGGSMWSQYVVEASGGSMWSQYVVEASGGSMWSQYVVCGGSKWRQHVESICGGSKCGSMWSICGGSKWWQHVNMWWKQVVVVEASGQHVESICGGSKWWQHVESICGGSKWRQHVESICVEQVVQVVEASGGSMWSQYVVEASGNVEICGGSKCGSMWSQYVVEASGGSMWSQYVVEASGVEYVVEAIICASGGAVVEASVEHAICVQVVAASGGSMWRWWKQVVEYVVEASGGRDSNPERRSAPCLPDATPNIYGLRFCATTQPLPTSSFTFPGNHKLHPNLPSCSPPRHVLSTPPQITAFSTTVFLQPRRLPPSQLPRHLHQHEELNNIQENKTYSSLHYQNVRLCHGRKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3G0</accession>
    <name>A0A423T3G0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002366">
        <property type="protein sequence ID" value="ROT70953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3G0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019417841" evidence="2">
        <location>
            <begin position="16"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="19405" checksum="7537022399D5362D" modified="2019-05-08" version="1">MRSFIAIAFVAALSAQLVGVGTLPSTGGGSHGGTGGYGTRGGGGHRFSRGPSIVQAQLVGVGTLPSIGGTGGGGYSSHGSGSRSSFGRSRVPQIVKAQLVGVGTLPSIGGTGGGSYGSHGSGSRSSFGRSTGPQIVKAQLVGVGTLPSTGGTGGGSYGSHGGGSRGGHGRSSGASIVRAQLVGVGTLPSGGGGGHAASAGGGYGSRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3J7</accession>
    <name>A0A423T3J7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010598</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002345">
        <property type="protein sequence ID" value="ROT71079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3J7"/>
    <dbReference type="OrthoDB" id="190089at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF47">
        <property type="entry name" value="GH22833P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="139"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="48346" checksum="4390CC43EFE009E7" modified="2019-05-08" version="1">MGDKELANGVEGPTPQSLITEEHVAAALRKDKGADVRLTSWSVEDFTRKGDNYACVVSSVRASYAKGKEDAEVVYVVKLNPCRNVESFKEFTRTIFEKECLFYLSLVPDLNRMLEGAGQTLLRVPRCFHGSLVDGREMIFLEDLRPRGFKMFDRKKGLDVAHASLILQELARLHAASVLLQAETPDEDLIKKYKFLKKDWLDGNKDSPHGILSLFDGYLRNAIEILETVGGYERAIAWVESLRPDLEEILTTKLGMGKFNVVCHGDCWNNNVLFRYDDEGRPLEVMLLDLQLCRRASPATDLNYLLYTSLTGDVRKPNLEKFLASYYATFASILNAADFGGDYPSETETKEDFREHNVVAAVFAMMIVPMVLMESDDVPELSTLTDDNLDDVMDEFKGQALKLLDSNPLMKPRFLAMFDEFMETGLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7C2</accession>
    <name>A0A423T7C2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Skeletal muscle actin 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_009276</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002171">
        <property type="protein sequence ID" value="ROT72340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7C2"/>
    <dbReference type="STRING" id="6689.A0A423T7C2"/>
    <dbReference type="OrthoDB" id="6331581at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT72340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="360" mass="40028" checksum="0DCF1233835EA727" modified="2019-05-08" version="1">MCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDAYVGDEAQAKRGILTLKYPVEHGIITNWDDMEKVWHHTFYNELRIAPEESPTLLTEAPLNPKANREKMTQIMFETFGMPAMYVAIQAVMSLYASGRTTGMVCDSGDGVSHHVPVFEGYALPHAMLRLDLAGRDLTLYLMKIMTERGYSFTTSAEREIVRDIKEKLCYIALDFENEMSVAAASSSLDKSFELPDGQIITIGNERFRAPEALFQPSFLGMECAGIHETVYTGIMRCDIDIRKDLFANVVMSGGTTMYPGIADRMQKELGNLAPPTIKIKIIAPPERKYSVWIGGSILASLSTFQAMWVTKEEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8L5</accession>
    <name>A0A423T8L5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002108">
        <property type="protein sequence ID" value="ROT72813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8L5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="204" mass="22712" checksum="BD63615CCCA0B8F3" modified="2019-05-08" version="1" fragment="single">MNEGVVSLDILPALADSCTAHLATLAKLPNTSLQPHPCPDFSPVLDLRDCDPAQGGEIDPLECAMILKEAKHNRRKKKTLPCKMNLCYGREHDDGCFPVKVEPAPDNACVPAHLKARLMYGGYPGYCVQNSKIHLIYVNEYLGPGRVPPLLLCWQRHPLAGPCPPQPAMPTIVPIIRYNCWNLKEDQINPTADCPEHTKWLDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFC5</accession>
    <name>A0A423TFC5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidine decarboxylase</fullName>
            <ecNumber evidence="3">4.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006332</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001808">
        <property type="protein sequence ID" value="ROT75136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFC5"/>
    <dbReference type="STRING" id="6689.A0A423TFC5"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004398">
        <property type="term" value="F:histidine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042423">
        <property type="term" value="P:catecholamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001694">
        <property type="term" value="P:histamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006548">
        <property type="term" value="P:L-histidine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1340.10:FF:000001">
        <property type="entry name" value="Histidine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF68">
        <property type="entry name" value="HISTIDINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="138"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="223"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="231"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT75136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="306" mass="34012" checksum="05A804B21D2C15C3" modified="2019-05-08" version="1">MVDYIADYLDTIRDRRVFPDVKPGYMRELLPEHAPDYPEPWENIFNDIERVVMPGVTHWQSPYMHAYFPSLNSYPSLLGDMLADAINGIGFTWSHPLSPFSFFFLFRATLLNPRDHHLVCGFLEAVIPDLQGAKDPCKSNALEPQSQYSAKPRNDIESLCNQDGTPTPSPSPPPSHTLLSAVSYHLLAPPPTFLHEFTFPPSPELPHPSFLYPSSPNPNIHHNPLLFFPHPLHPSPTPPPPLSPQPPPPLPPFPSPPTPPNPPFPPPFPHSFPPLPLLPPLLPLLSLPLLPSTLQPPTTVTTATPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGA2</accession>
    <name>A0A423TGA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005913</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001760">
        <property type="protein sequence ID" value="ROT75520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGA2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="45109" checksum="DFC163C019538CAA" modified="2019-05-08" version="1">MPPPLPITANTPSAPLPLFHSHPTPPPPSASKDVQREKVKRLRSAVEMDGQEAALPCPSPRPSFIPSPPPSLPRPPLPSPSPLASLPSPLSASPPHLTRALAPRPLSLPSPSRSLPRPSLPVALPPPSRPSPSLRLPLPPSLPRPLSPSPRSPLPPIALSALSPLPLPPRPRILAPSPPLPSLALSPSPPPALPPRLSPLPSLPALLACSPLALPLRSLPQAYLALPSPRFPPLALSPLPSASAWLLALVSLPSPPILSLLSPPHAPSAPSLGLSSPPPPRSLPSSPSSCPPLPGILSLALVSPPLPLPPSLAALCPSLPSPHPPTGAPRLRPTSPGSLALALFPSLPIPPHRPLSPSPPPSHRRLSRRSPTLLAHYHLLIAGSGYKRQKWDNNTGSLQRNRVQGPRYSTVLSRDEARVNCGGKCGCVKGGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGJ9</accession>
    <name>A0A423TGJ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdenum cofactor sulfurase</fullName>
            <shortName evidence="4">MCS</shortName>
            <shortName evidence="4">MOS</shortName>
            <shortName evidence="4">MoCo sulfurase</shortName>
            <ecNumber evidence="4">2.8.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor sulfurtransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005864</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:42636"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:82685"/>
            <dbReference type="EC" id="2.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.9" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001756">
        <property type="protein sequence ID" value="ROT75576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGJ9"/>
    <dbReference type="STRING" id="6689.A0A423TGJ9"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008265">
        <property type="term" value="F:molybdenum cofactor sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03050">
        <property type="entry name" value="MOCOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028886">
        <property type="entry name" value="MoCo_sulfurase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MOSC" evidence="6">
        <location>
            <begin position="759"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="917" mass="102033" checksum="CDB327D3648491BC" modified="2019-05-08" version="1">MAAVLEKLKIPPNYDVERVIKEDFDRLKGHYYLDHAAATLYSDSQIQAASAELQNSLLGNPHSRSSVSDAATRIVDSVRQRILDHFNTTVDEYDVIFTSGATQALKIVAEHFNWHGSEETCTENGDINISKNNPEPTIQLENGHVSNSSVQEEVFDSHRKEKTHGAFVYAMENHTSVLGMRGPAAANGADVYCLQTEQLHHVLDKCKTFPSKTNLNHTDAREKDNSVRAPNGNRKKKRHCLFAYSAQCNFSGVKSPLVWIDKVQKGALDPVLKRQPLNKNNAHLPENTADDCIWYVVLDAAGFTATCPLDLSQWKPDFVPVSFYKIFGYPTGLGCLLVHQRAWTVLGKTYFGGGSVLMIDSRRIVAVPRPVLHDKFEDGTLAFLNIPAVRNGLDTIENHTGGMKNIQQHVFNLARYTHHSLRSFRHGNGAPVVEAYPKDANWDVRTQGSIVNFSILKSDGTYVGYSQVEKFASLYNIHLRTGCLCNPGACQKYLDISEETLIQQFKAGHVCGDAHDLVEGLPTGSVRISFGYMNSYKDADQLLQMVKECFVEGNLIIDSSWIEVQPCLVEKESHHMRGQTESEKLEIVNRNEEHFDGDESTVRTMNGYLDSDVTNTPLQVENERNVTSAPPLKLTNIILYPVKSCSGISVREWSIGEEGLKYDRQWMIVTNSGTTLTQKRLPIMSLIKPSIDMINGLLKLSFKGESIAVPLEPQDGSTRDASLCRGVVCGDRIRGHDCGPEVGAWLSRVLQQPDLKLMQQLNKRTGKLDSKGNGSLGESLSFANESQYLVIHRASVRKLLQDISEKGLAKLTEEELVSRFRANLVLDGGEPYEEDSWEELLLGKLRFKVQGGCNRCQMVGVIPETGERMKEPMITLAATRGSYMKFGIHAAAVSSVSIDETISVRSKVRVTSNADLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THI2</accession>
    <name>A0A423THI2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coiled-coil domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_005509</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Midbody</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCDC124 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001711">
        <property type="protein sequence ID" value="ROT75923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THI2"/>
    <dbReference type="STRING" id="6689.A0A423THI2"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coiled-coil" evidence="5">
        <location>
            <begin position="126"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="43"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="174"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="209" mass="24277" checksum="03075B9C6E161F96" modified="2019-05-08" version="1">MPKKFKGENSKAVVAKARKAERAADEKAKKDKAIEDAYWEDDDKQVKKKMARKEDKEKKRQAELEKKAELRALVENEESTLTPKATPQKVTQYELKRNQERQVELEQQLKEKEDSKTHLDNPLIENLNRVEGDVISASGIDAALSALNTDDSNTDRHPEKRMAAAFKAFEEKRLPQIKKENPNLRMSQQKQMLRKEWLKSPENPLNQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THU9</accession>
    <name>A0A423THU9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_005327</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001695">
        <property type="protein sequence ID" value="ROT76080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THU9"/>
    <dbReference type="STRING" id="6689.A0A423THU9"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="13">
        <location>
            <begin position="51"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="14">
        <location>
            <begin position="250"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="50126" checksum="BBDDDDA3AC2C8F3E" modified="2019-05-08" version="1">MREIIHVQMGQCGNQIGTKFWEVISDEHGIQPDGQYAGENPELRDVQLERVNVYFDEGTKGKYVPRSVLVDLEPGTIEAAKSGPYGALYKPDSFVYGQGGAGNNWAKGHYTEGAELVDSVLDVIRKQAESADCLQGFQLAHSLGGGTGSGLGTLLVSKVHEDYPDRIMTTISVMPSPKVSDTVVEPYNATLSIHQLLENSDETFCIDNEALYDICFKTLKLQNPSYGDLNHLVSLAMSGFTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFVPLTPRGSQSYRALSVPELTMQMFDAKNMMAACDPRHGRYLTVASIFRGRVSMKEVDEQMYNIQSKNSSFFIEWIPHNVKTAVCDIAPRGLKMSATFVGNTTAIQDLFKRLCEQFTAMFKRKAFLHWYTAEGMDEMEFTEAESNLTDLIAEYQQYQEATADDESLGEEQYEEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJA9</accession>
    <name>A0A423TJA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein msta, isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001657">
        <property type="protein sequence ID" value="ROT76477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJA9"/>
    <dbReference type="STRING" id="6689.A0A423TJA9"/>
    <dbReference type="OrthoDB" id="3174329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF2">
        <property type="entry name" value="AT24727P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="473" mass="53752" checksum="0B3409E9EA049EB0" modified="2019-05-08" version="1">MVASRDLKAGDIIFKDEALVIGPKTITEPVCLGCYKRVDGSYRCRVCEWPMCGPACEKSPDHQPECVVGREIGSPIDIQNFDEPNHFYELVFPMRCLALKKKSPKKYEQLLALESHYEDRKGTYVFKENQRRVVHMLRNYFFLQEFSAEDVDSSEKSIHTITGIIDVNALEIRLPESEILGLYPVFAMLEHSCTPNTKHTFNASRQVIVKAAVDIKRGEHLSTMYTHVLWGTIARRDHLKHSKYFMCTCFRCADPTELGTHFSALRCKSCDHGFVLSAAPLDELADWICTSCNATMTAEKVKNINLKLGEEIENVIAMPTVEKLEELVNRLAKTTVHPNHFHLFVARHTLLQLYGRDPNSTGEDSMKKKEKLCQDFLKVCTALDPGMARLAPYAGVALYEYHLAVLSRTRQDPSEKHVDQSALRKDVETAKALLQQCIRVLQDEPKDQPEGALCQVAQENLAELRQWEATLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJJ7</accession>
    <name>A0A423TJJ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nephrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001625">
        <property type="protein sequence ID" value="ROT76646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJJ7"/>
    <dbReference type="OrthoDB" id="6379592at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="124"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="320" mass="35554" checksum="397FEF8E0AF4C328" modified="2019-05-08" version="1">MIKSRRQRMATYGNSAPLITPVLHGAGKQAFKLSVNERRELRKPPLSHFLTPEILAYVSALPVPQLPSLPLTDSTLPLSLLCSTSVFRSQLSLSIRGAAKICKIAINVAELWKFDWQLGGLNAPVCSEGQATSYAVSRYEDAEIKCSVDANPARSTFRWMFNNTSEFIEVPQGRFSSDSNASTITYTPMTTLDYGTLLCWAVNSIGTQKWPCAFHIVPAGKPDPPTNCSVGGVGAVGEWYLGRGRVQLRGRGRYFLPAAGEGRGRLSRPQCDLFHARVHGGRPSPRPEVRPLHNRPQRQGRQYPRPPHHRRPRVRLSTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN96</accession>
    <name>A0A423TN96_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001460">
        <property type="protein sequence ID" value="ROT77905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN96"/>
    <dbReference type="STRING" id="6689.A0A423TN96"/>
    <dbReference type="OrthoDB" id="8191242at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="2">
        <location>
            <begin position="132"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="56569" checksum="7EFA4CB000D332F2" modified="2019-05-08" version="1">MPRNTRTSSAAAAVSPDDPQPSTSAGPLSFYDDSSDDESGERFVPRGRVLIEDSSDSDLGSDSGDDSDLDYVSHDTSLDEDEPLSAYARRLRERNSPGQPGFRWRKKENVPTRYGFRAQPGVNTPGVDSDSSPLELFSLFFTEELMDMIVRETNRYHRQKPGPSSHMKDWVDTSVSELGVFIGLRMAMGINQKPEQRSYWSTDLFYHSPLFPVTMTRDRFDQLSRYLHVVDNEGSHPPDDRLWKLRPAIEILQRQFSSVFTPPRRITVDESLWKFRGRFVAVTYNPSKRSRFGVKVYKLAASEGPSNGYICAFEIYTGRDRSDIPASQRAVIHLMGAAGLFDKGYDLYTDNWYTSPTLFHYLQSRRTNAIGTVRTNRKFMPTDLQVKARGQVDSRSTPTGMLCLQWRDRRVVTLLSTVHKSEMVATRSRSGFERIKPKVVVDYNCGMKGVDNSDQLACPSEDPHPLQGGRYHDHVCAFSDKNVTYAPRSSRHMHPTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQ48</accession>
    <name>A0A423TQ48_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002694</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001358">
        <property type="protein sequence ID" value="ROT78587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQ48"/>
    <dbReference type="STRING" id="6689.A0A423TQ48"/>
    <dbReference type="OrthoDB" id="6343205at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000817">
        <property type="entry name" value="zinc finger protein 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000433">
        <property type="entry name" value="zinc finger protein 384 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="12557" checksum="E264EC6D47744E36" modified="2019-05-08" version="1">MHKSAMQMHSREAHRSEVKPHQCQQCLKSFSSNHQLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGEYPVAPPFSIRVPDVFCLVLGSPCWAPGGSPGLLAVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TR71</accession>
    <name>A0A423TR71_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">39S ribosomal protein L13, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TR71"/>
    <dbReference type="STRING" id="6689.A0A423TR71"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000005">
        <property type="entry name" value="39S ribosomal protein L13, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="183" mass="21137" checksum="E68B4C45488E68F0" modified="2019-05-08" version="1">MEVSAGGESPQKVQSMATFGCGILYDAKWQNPFHTANKIKDYLTGSTKPIYHPLNDCGDHVVVINSRDIAMPGIEWEKRVYFHHTGYPGGASWTLAWELHQKDPTLVLRKAVYNQLSKNLLRRGRIARLHIFPDDKIPDSILQNISGQIRQLRPVPKRLDHYSEEEVKNFPKVFDWPREYIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRZ0</accession>
    <name>A0A423TRZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001272">
        <property type="protein sequence ID" value="ROT79219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRZ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045600">
        <property type="term" value="P:positive regulation of fat cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034450">
        <property type="entry name" value="ADIRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39227">
        <property type="entry name" value="ADIPOGENESIS REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39227:SF1">
        <property type="entry name" value="ADIPOGENESIS REGULATORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="540" mass="60990" checksum="D063404A70AC7CAB" modified="2019-05-08" version="1">MAPLKSDDAPLKRDAAAQTMAPLKSDDAPLKRDAATQTMAPLKSDDAPLKRDAAAQTMAPLKSDDAPLKRDAAAQTMAPLKSDDAPLKRDAATQTMAPLKRDAAAQTMAPLKRDADTHKTGPGKKSVDAQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQEKLLPAHPRQQEKLLPAHPRQQEKLLPAHPRGRPTPQVTQQSTWNPYPVTAHSAHSQSAATCPLIQPIRVSEKERPFLIGKGGHRIQALCTKHRVAVDTKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSN3</accession>
    <name>A0A423TSN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glutamate-gated chloride channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_001823</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001241">
        <property type="protein sequence ID" value="ROT79448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSN3"/>
    <dbReference type="OrthoDB" id="7357196at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051360">
        <property type="entry name" value="Neuronal_Pentraxin_Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277:SF125">
        <property type="entry name" value="B6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277">
        <property type="entry name" value="PENTRAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019465648" evidence="11">
        <location>
            <begin position="29"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="763"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="800"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="862"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="13">
        <location>
            <begin position="42"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="12">
        <location>
            <begin position="251"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="494"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT79448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="895" mass="101747" checksum="B6CAA67F8CB04022" modified="2019-05-08" version="1">MTRPQRPQRVVVAAVLKVLSTVVSAAAAGPMAEVKVFGMQLDTWAPPLPDVVVTYNLSLNIPQDEPSDFKEVSVCYRAKPSTLTSYETHISFARSDQLNDVLHLYRRGEHHGFYFNGVRQFGFPNLTSPVNLHQWTHYCHIFDNGMYVAFVDGEEKARGAIATKEVSLNLRGMLTLGQEQDSLAGNYDVDQAFRGHIAQVNIWSRIVRQEEVRHQASCMEFAPGDIFSSDRDAVNVAGVSVEEIPISDLCLTTREFVIFPEAQYMAPSRRACHRVGYQVYSPDSREENTVLHLESLEFAEECLSNYHLWIGVTDEAEEGVWRKFTTNEVVGETVFELFEPNGAEGENCILMFLPNGLWVDTSCSIQWPACVPCEVDRSSPLRLRGFCYKNEAETFYEVLGYRGRKPYMHGYFGIMIFRNDSGVWQMYDTTTDENVAYLKVPSISSYPIGVHTWTLQRSMCEHLVGSKIQLSLSICNSSEFTCGNGDCIPREKRCNTQNDCVDFTDEDNCEMIVLPRGYRSNRPPESAIPGKPMHVGAVVHILRFVEVNDVGGVLDMEILVELIWQDSRVTYLNLGDTLEWNRLSQAESSLIWRPKFKFPNIQNGNVKILDEELFLKKIGIPQSPDFNDVRMETVYAGNAAYVIQQQHYSGSFACFFDVFFYPFDTQTCFISIQLAAIRKEVVSFSEEEAKVEYLEKKVLPSFVVTQYKAEVTDGGNNETRYSVLKVEFMLARRWTVIVLGVFVPTSMLLIIGYTTLFVNLSLLDVRLAVSLTTLLVLYTLFNSTSDSLPVTAYVKMIDVWFFYCIFLLFFIIVTHVVSEHLQNRRRVLDVHPALQAKLPKNRGSPVSISSTAITTGRSPERLLVVVRFYIIPAIVFVFNLMYWAILLGRFEVFNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU47</accession>
    <name>A0A423TU47_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU47"/>
    <dbReference type="OrthoDB" id="6515930at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="151" mass="17431" checksum="6A2BC8F9F551807D" modified="2019-05-08" version="1">MLQAECRNSQPRADDAHIRVVGVQQGLWTVPSNQVFLRYNFSVPEDEPVPTLFNYTICYWIRGERAASLFTHVSYAVSDLDANNILLYQGHDRLLAFVNGVYQRVPQAREFPFVPGVWHHLCHVVEEENYAVYWGGKEFVSGKLAEFLELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU80</accession>
    <name>A0A423TU80_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001321</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001171">
        <property type="protein sequence ID" value="ROT79951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU80"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="3">
        <location>
            <begin position="148"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="4">
        <location>
            <begin position="326"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="626" mass="70146" checksum="88C48990B4460C34" modified="2019-05-08" version="1">MNLTPVPLEIRGGVPVLNFEFTDLPIREFDLPTPSPVCAASHSPPQVNNEVLQDILSQKLAFQDGYNILEKIFHDYPTVLPSKDRLIGSTDLIEHSISLEPDAKPVYIPSYKIPHSKRKALENEVQGMLDMNLIKRSNSPWASPMILVPKKDGSFRPVVDYRKLNAVTIPEPFPIPNLRLLLQDIGSGNLVFSTLDLAKGFLQVPVAKESRPLTAFSTHMGHFEFLRTPFGLRIRTSSKRRANHQPWKVPILSVKLDFLGHTLTSNGIAPNQNKVQAVIDFPRPQNQKDLKSFLGLSGFYRPFIKDYGSIAQPLTTLLKKDVPFEWAKETEDSFLQLKALLANAPVLAFPDFELPFVLTTDASSVGLGATLHQKVNGKLRPIAFASRTLKPAERSYHTTDRTLSYHLCTPSLPGVDTRYKIEVHTDHSALTTALHGRDPHGRRARAIEVLAEYDVTIVYLPGRQNVVADALSRAPLPSPAELQACKSTPFPPSFAKRHEARTTAPVLANVANQPVDPPSEEEIRRAQREDPVYMDIIGKLERGEPLVPVRRLPVRQFYLADSGLLFRRATPKKIKGRRGLVRDVVVIPESLEPRVLQLVHESREAAHCGVYKAIQMARQRFFSHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TV72</accession>
    <name>A0A423TV72_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000925</name>
        <name evidence="10" type="ORF">C7M84_000930</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001128">
        <property type="protein sequence ID" value="ROT80346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001128">
        <property type="protein sequence ID" value="ROT80351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TV72"/>
    <dbReference type="STRING" id="6689.A0A423TV72"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000003">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF124">
        <property type="entry name" value="ARGININE METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="58"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="8">
        <location>
            <begin position="165"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT80346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT80351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="342" mass="39982" checksum="698F116E5773A975" modified="2019-05-08" version="1">MENKTEKEKVEKMPIDEMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNAMYHNRHLFKGKTVLDVGCGTGILSMFAAKAGAAKVYGIEMSNIVEHAKKIVTANNLDNVVEIIQGKVEEVTLPVEKVDIIISEWMGYCLFYESMLDTVLYARDKWLATDGMLFPDRATLFVSAIEDRQYKDDKINWWDSVYGFDMSCIREVAMTEPLVDVVEAKQVVTNSCLVKEVDLYTVKKEDLAFSSPFHLQVRRNDYVHALIAYFNIEFTKCHKRTGFSTAPEARYTHWKQTVFYFDDYLTVKHGEEIFGTFTMKPNERNNRDLDFQVEMEFHGELSECRESHKYKMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY31</accession>
    <name>A0A423TY31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000989">
        <property type="protein sequence ID" value="ROT81358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="538"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="682"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="784"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="816"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="857"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="895"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="936"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="969"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1207"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1239"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1349"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1420"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1460"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1498"/>
            <end position="1516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1618" mass="178242" checksum="92E775D305C0B6F9" modified="2019-05-08" version="1">MPSLFRHSSPLSPSSRFPYSHFFSLFYSPRFPYSPFFSSVSSPRFRRIPILALPLISSLAFPIPDFFPSPSLSRFLFPSSPLCSSPLLSLFPFFSSFSPLFRFPYPILLLSLAPLLSLFPFFSSCSSSPPFPIHFLSSSLSLLSLSLFPSSLLSPLLAFPYSPFSSLCSFLAFPIPILLPLSLSPPLFPIPVLLPLSSSLPAFPYSILLPPVSSSSLFPIPFFSLCLSFALSLCPFFSLYSLSSLFAYFAFFSLLPLPRFPIPHSSLFFSSPGFPYSHSSPLSLLSLSLFPFFSLSLLSSLSLFPFFSLSLLSSLSLFPFILSHSLLRLSLFPFFSPLSSPLSLSLIPFFSLSLPPLRFPLIPILPPSLSLLAFPIPILLLPSLSSPRSPISFFSSLSSSRFLFHSFLSLLSPRISAIILLPFSPLPFPYSHSSPSLSSPRFPYSHSSPSLSSPRFPLFPFFSLFPIFSLSLLSSLSLSPFSPSLSLSSLSLFPFFLSPPLSTLPSFFPIPFFFPLFLSSPPPFAFFPNSILLPLSSFLVFPPITILLPLSPLLAFLIPFFLPLSSLSLAFPIPFFLLFSSPLLVSPYSHSSSPSVSSSRFSLFPHSFSFVSLSPPRFSPIPILPSPSLSSSVSLIPFFFLLLSPRFPLSIPFSSSLSLRFPIPILLPLSPLPPSSPPRFPIPFFLLFFSFPSSLSLFHSFSFSLLSRFSPYSILLSVSSSVSSPRFPYSHSSPSLSSPRFPYSHSFSLSLLSRFPYSPFFLPRLPLRAFPIPILLPLSPLPSFPIPILLPLSPLCFPLFPILLLSLSPRFPYSPILSLCFSSSFPIPIFSLSPLLSSLSLIPFSPSHLSPRFPYSIFPLFSSHLGLSLFHFLPLSSFSFSLFHSSPLSPLRFPISILLPSCLLSSLSYSHSFSLLSPSSFPYSILLASLSSSCAFRYPIILPLSPLLAFPIPILLLSSPLPRFPYFPFFLLSLLLPAFPIPFFLPLSLPRFPYSHSSPSVSSLFCFPYSILLLSLLSSLSYSHFFLPLVSISSLCPYSHSSPSSPLPLSYSHSLPSVSFCPLFFFPIPFLPPSVSLPSLSPIPHSSPSLFPPRFPFPILCPLSLSPLSLFHSFSLSLSLFAFPYSHSSPSLSLSSLSYPILLNLSPLFCFSLFRYSSPSLSSPRFPYSSSPSVPLLAFPYSSFSPLSSSLRFPYSLLLPSYHLSRFPPLGGFSFFSLCLLSSLSPISHSCSLSLPLSFPPIPILLLSLPLPAFPIPFFLPLSLSLAFPYPILLPLFSLRFLPIPILLLSPPLHRFPYSHSPISLCLSPAFPIPSSPWSVSSLAFPIPILFSLSLSCFPYSILLPLSPLLLLSLFPILLPLLSSLVRAFPIHYSSPSPLFLRFPYPFFSSLSSLRFPHPILLPFSLLAFPIPILLPLSPLLAFPIPILLPLLTLFAFPIPHSSPSVCLLRFSLFPILLPLSSSLSLFPFSFFSLLSPLTLFFLFPFFCLSPPPSLSPIPILLLSLLSSLSLFPFFLSPVSSPLLSYSHSSPSLSLLAFPIPFSPSVSLSSFPIPNSFPLPLFPILPLPWVPGYEVQMRVPGLGVQGQGCQGMPIGVMRVPRTAFDAARRRPQRPRADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYM0</accession>
    <name>A0A423TYM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mas</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_025305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000958">
        <property type="protein sequence ID" value="ROT81540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYM0"/>
    <dbReference type="STRING" id="6689.A0A423TYM0"/>
    <dbReference type="OrthoDB" id="6656697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019136263" evidence="3">
        <location>
            <begin position="20"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="4">
        <location>
            <begin position="92"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT81540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="332" mass="35342" checksum="4E144D77DB163B72" modified="2019-05-08" version="1">MDRVWLLSALLLAVASGAAQRLGIIATDIGVPAVPGGLTGPDNTALPPGCFCIPINQVCPFQTNVRIALRPVAERCPEMKECCRTNGSTQPPITAPLGSCGRQNALRRSNIIHGAALFGELPWMAMVLDRRGRNLVARLGELDFSTPQDSPLYPHRDVLVDNIIVHPQFNPQTLANDVALLHLSVPVNTAAAPNIGTACLPSQGQFFQGLRCVVSGWGGDPTIPGNRFQNTLRVVQVPMVDSFACQQRLGAARLGSNFTLDQTSFVCAGGVEGNDACTGDGGSPLVCQNDSNKSWTVVGLVAWGLGCAQREVPGVYVNVASYANFIRQNVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U008</accession>
    <name>A0A423U008_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000894">
        <property type="protein sequence ID" value="ROT82021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U008"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="722" mass="80353" checksum="D7FB4513F70B7C43" modified="2019-05-08" version="1">MVRPQSLRERRPQPPRERRPRRVRLQPSRERRPQPPRERRPQPPRERRPHPEGEEAAAPKERSPEGRGGRSPRGEAAAPEGEEPPRSSRSPEGEEAAAPRERSRSPPRRGGRSPRGAAQPPRERRAAEGEEAAAAPREEEAAAPEERRPQPPRERRPQPPRRGGRSPRGRGGPAPEGEEAAAPRERRPQPPAAPEERRPQRERRPQPRGRGGPQPRRPHPRGRGGRSPRGKEAAPRGEEPQPPRERRPQPPRERKAAAPEGEEAAAPEGEEAAPEGEEAPPRSPRGRGGRSPRGRGGRSPRRRGGRSPRGRGGRSPEGEEAAAPRERRPQPRGREEPPAPEGEEAAAPRRGGRSPRGAAEERRQPRGRGGRSPRERRRSPRREESRSPRRRGGRSPPEPPRGAAAPEGEGRSPRGRGGRSPEGEEAAAPRERRPQPRGEEAAAPEGRGGRSPPRRGGRSPRGEERSPEERRPQPPRREAAAPGERQRGRPQPRERSRSPRGRGGPEAAAPRRGGRSPEERRPAARRRGQPPASPRERRPQPPKERSRSPEERRPQPRGGRSPRGRGAAAPEERSPAPEERSRSPRGRGGRSPEGERRRSPRGEEPQPRGERPQPRRRGAQPRRERRRSPERGGRSPRRRGGRSPRRRGGRSPRGREERRSPRGRGGRSPRGEEAQPHAPRGEEAAAPRREAAAPEEGSPERGGRSPEERRRSPEERSRSPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U023</accession>
    <name>A0A423U023_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000890">
        <property type="protein sequence ID" value="ROT82060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U023"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="302" mass="33238" checksum="5B39AE8B82EC4561" modified="2019-05-08" version="1">MSARARHAPDPGPTLIRISPARIHTQVTQSVRYRPLRSLLLLVLLVIVSLFVLLTLSQVNSALADNRRRASKLAAIIVRNSILVTYSARHSNLSSTHHEPHPPALSPPHLHPHPSATSTRRRSPSLPSPPQTARPQDERHRPNPAHDPARPHHSPRPPSLELVGRREKPSERVTRHFLRKLGCAPEDAGCESDQRQPRRTALRGLAPALADGGAAGTTVQGVPAANATPPAERQDDYGDRREPEALPTELTEEQLRALPPCPDIPPDLSKSRLPPSPLLLPKAIRLALAVRLFSGWRWSFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0B0</accession>
    <name>A0A423U0B0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative cyclin-dependent kinase 5 activator 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024684</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin-dependent kinase 5 activator family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000876">
        <property type="protein sequence ID" value="ROT82153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0B0"/>
    <dbReference type="STRING" id="6689.A0A423U0B0"/>
    <dbReference type="OrthoDB" id="7676799at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030426">
        <property type="term" value="C:growth cone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016533">
        <property type="term" value="C:protein kinase 5 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061575">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004944">
        <property type="entry name" value="CDK5_activator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23401">
        <property type="entry name" value="CYCLIN DEPENDANT KINASE-5 ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23401:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5 ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03261">
        <property type="entry name" value="CDK5_activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="209" mass="23385" checksum="BA123FC50AE5A413" modified="2019-05-08" version="1">MGTVLSFSPREQKPYYGDYTLNNHNYETLNNVRNKEKLNIQKALSCYNIRPSSMGNLDLVRVNNNNAHTPTEKLPPKAILTSAPSTHTHDLRGALVPSRPSQHLSSSGGASNVTTPTGVSPTKKTVIQASTSELLKCLGLYLHRTCSRLRDFQAGDAVMWLRTVDRSLLLQGWQVRPSAGRSSRRSCFRRLALHARSLWSLLLLAWSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U651</accession>
    <name>A0A423U651_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000585">
        <property type="protein sequence ID" value="ROT84181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="418"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="745"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1211"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1308"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1508"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="277"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1211"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1526"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1590"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1664" mass="175029" checksum="9311D46C35DC0BEB" modified="2019-05-08" version="1" fragment="single">MSRMVCPSSEVHQKFTFLTQAESAVCPTDQPASIQPVSVPLWKAQCSRLVDHLLGFLFRVYSAPSRAHRPPPGRPPRAHRPPPGRPPSGHRPPPVASPSSSGSQDRPSWAFLLFGFTDRLSPGRPPRFIHDASWSCSQVFLHLLGRPPFLLTQNRLLGVLSSGSTANRFSWASPPVRAPQDRLLGVLPRAHSHRLASWASSWGSQTASWASFPPVGSQTPPGASSSGLTDRASPRCSVPPPLSHQTASRGVLPRAHRPPLSGVLLALTSYRLSLGRPPLAHRQQLPPRRPPRGPTDRLLGVPSSGLTGPPSWASLLRAALLTRPPLARLLGLQTASSGLHRPLLGSFPSPARAHRHRLSGVLLGLTDRLLGVLLGLTDRLLGVLLGPVQTASWAPPRGPQTASWDVLTDRLPGAPRTHRRLLGLTDHRLPHRPPPGRPSRAHRPLSGRPPRAHRPPPGRPPRAHRRLLRAFLLGLNRPPPGRPPGAHRTASWASSSGSTDRLLTELPERIERGVHQQQATKDTKGPYPGAIAPPWETLTDTSLTGASSSGSQTALLGVPLGAHRPTSGPFLLGPQDRLLGPGALLGATSQTASWGSTDTPGASLLGGLFTGPPHWASSRPHSTASLGVPSYGLTRDRPLASSFGAHRTASWCVPILGPIRPPLLGRHPPRALHRPPPWAVINLGIKQTASWAATRPSWGLHRPPPLGVPPRAHRTAILGRGPPAGAQTAPERRVLLGASQNCHDWAVPPRAHRPPPCASSSGSDRPGARRVPSSSGSQTASWRPPRAHRPPPGRPPRVTDASWASSSALTDRPPGATQTPPGPSSWGSQTAFPGRPPRAHNRLLGVLLGSQTASWASSSGFTDRHLGRPLLWAQTASWASSWGSQTDLLGSSSGGSQTASWLLLGTDRLLGVLLGLTDRLLGVLLGLTDRLLGLTDHLLGVLLGLTQTDRLLGRPPRAHRPPPGRPPRVTDRLLARTASCVLLGAHRPPPGSSLTPGRLLGLTDRLLGLTPVLLGSQSASWASSSGSQTASWAVLLGPSQTASWASSSAHRPPPGSSRAHRPLLGVLLGLTDRLLGASLGASSVLLGLTDRLLGVLLTGGLTDRLLGVLLGSQTAQTASWASSSGSQTASWASSSGSQTASWASQTASWAFSWGSQTASWASSWGSTDRLLGPLGLTEPPPGVLLLTDPSWAPLGSQTASWASSWGSQTASWASSSGSQTASFPLGAPPRAHRPPPGRPPLGSQTRLLGSSSGSQPLPDLTDRLLGVLLWAPTTGLPWAQDPSSGSQTASWAAPPGLTDRLWASSFGLTDRLPGRPPRAHRPPPGRTDASWASSDRLLGLTDRLLGVLLGLTDRLLGTAPPAFSSGLTDRLLGVLLGSQTASWASSSGSQTPPDVLPGHRLGLTDHLLGFLLGLTDRLLGVLLLTDPLGVLLGAHRPPLGSFLGLTDLLLGLTDRLLGVLLGLTDRLLGVLLSQTASCVLLGLTDRLLGVSPRGSQTASWALLQTASWAHRPPPGRPRAHRPPPGRTSWGSQTTSWASSWGSQTASWASSSGSQTASWRSSSGHRLTTGRPPRAHRPLLGLTDRLLGAPDRPPGAHRPPPGRPPPGAHKTLLGLTDRLLGLITASWGSPDRLLGVLLGLTETALLGLTDRLLGVLLGLTDRLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U788</accession>
    <name>A0A423U788_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022267</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000530">
        <property type="protein sequence ID" value="ROT84539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1377" mass="150166" checksum="4BA3A19623AC9B13" modified="2019-05-08" version="1">MLFFFLPSVVHALLFPQSVIHALLLPAFRRPCSSLPAVRHHALLPVPSVSMLLLCLPSSMLFSSRSPSSMLFFLCRPLSMLFSSSRSPSSMLFSSCLPSSMLLLFPQSVIHALLPVPSVVHALLFFRSPSSMLFFFLPSVVHALLFPQSVIHALLPVPSVVHASSCLPSSMLFSSRSPSSMLFFLCRPSSMLFSSSRSPSSMLLLPVPSIVHLFFFFRSPSSMLFFLCRPLSMLSLLPAVRHPCSSSSCLPSSMLFFFPQSVIHALLLPAFRRPCSSLFPQSVIHALLPVPSVVHALLFFPQSVIHALLLPAFRRPCSSLPAVRHPCSSSCRPCPSLSSSRSPSSMLFFFLPSSSMLFLPAVRHPCSSSSCLPSSMLFSSSRSPSSMLFFLCRSVCSLFSSRSPSSMLFFLYRPSSIPLFFPQSVIHSSSCAVRCPCSSLLPQSVIHALLPAFRRPCSSSSAVRRPCFLFFPQSVIHALLPVPSVVHALLFFPQSVIHALLPVPSIVHTHLFFPQSVIHALLPVPSIVHSSLLPAVRHPCLFFLCRPSSMLFSSSRSPSSMLFFLCRPSSMLFSSSRSPSSMLFFLCRPSSMLFFLCRPLSMLFSSSRSPSSMLFFFLPSVVHALLFPQSVIHALPVPSVIHALLPCRPSSMLLSSSRSPSSMLFFCASVIHALLPVPSVVHALLFFPQSVIHALLPVPSVVHALLFFPQSVIHALLPVPSIVQLLSSSAVRHPCSSSCAVRCPCFFLPSVVHALLFPQSVIHALVLPVPSVVHALSSSRSPSSMLFFLCRPLSMLFSSSRSPSSMLFFLCRPLSMLSLLPAVRHPCSSSCAVHRPCSSLLPQSVIHALLPSSIVHAPLFFPQSVIHALSSCAVHRPCSSSSSRSPSSMLFFLCRPLSMLFSSSRSPSSMLFFLCRPSSILLSSSRSPSSMLFFLCRPLSMLFSSSRSPSSMLFFLCRRCPCSSLLPAVRHPCSFFLCRPSSMLLSFFPQSVIHALLPVPSIVHAPLFFPQSVIHALLPVPSIVHAPLFFRSPSSMLFFLCRPLSMLFSSSRSPSSMLFFLCRPSSMLLSSSRSPSSMLFFFLPSVVHALLFPQSVIHALPVPSVIDALLPVSSIVHALLFFPQSVIHAHLPVPSVVHALLFFPQSVIHAHLPVPSVVHALLFFPQSVIHALLPVPSVVHALSSSRSPSSMLFFLCRPSSMLFSSSAVRHPCSSSCAVRCPCSSLLPAVRHPCSSSCAVHRPCSLSLPQSVIHALLPVPSIVHALLFFPQSVIHALLPVPSVVHVSSSSRSPSSMLFFLCRPSSMLLSSSRSPSSILYFLCRPLSMLFSSSRSPSSMLFFFLPSVVHALLFLQSVIHALLPVPSVIDAPLLPAAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9A1</accession>
    <name>A0A423U9A1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative activating transcription factor 7-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000344">
        <property type="protein sequence ID" value="ROT85261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9A1"/>
    <dbReference type="STRING" id="6689.A0A423U9A1"/>
    <dbReference type="OrthoDB" id="2434995at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="676" mass="71495" checksum="B91052CBE408BE2A" modified="2019-05-08" version="1">MKAMDQAAPMITVPAGVLKEFMSPANSRTPTPPATASVTTSAVSKSSTPTPAASSNSRTPSPALPSSSETPSASLHAEKVSVDSPARVSLTNGDINSDSSTQDVDLRMESDTSDASLTESSRAVDEKTSVEGASEGIVNGTGVKRPSDEDNELKKPDLKKIRVFAPAEEDGFKKGDISIAVQEFNQHLDKASKKLEEAGKTDLDNIKADSFNSANSFFNDDKTNHTVQPPANNVRSYDVEVISSPSKDIEVLPVLPNDKDKETLTPVSVEKAPAQDRESKHIKKKLQRLSRKDLENMIMRLFSEKILHQTELGKLKQLCERSESTLETNRKKTAQFHKEVEDLRKVTNRLSAEHAARKGQYVAPIRIKRSVGIQASPHIINKGILHANGSAGVIKTIAPRASALVGVGNASSPIRPTTVQSTDTRKQSIPPPNVTFNTQMIPTSSSTNNVVSGGPVGLLASSQGVSNIATNSSLSTVTNPVASIGTVRPSAAGQMLMVAQPGMMQTIPRASGAGVVSKTTSAVIPVAQRRVVHTSLGNRVAAPRPAGLGPTPGTLVKVPVTGATQLVAIPQAGQVVLLPPVSGGQPTTALVVSNVTINSQPHSRLTALIATLAVVISLTDLSGFISVSDTKYARPTTYSHLRRPSATFWTALVDRGMSLPSNPPTQTLIPISEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA65</accession>
    <name>A0A423UA65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000245">
        <property type="protein sequence ID" value="ROT85575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA65"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="433" mass="47183" checksum="08F0913F7DF3B609" modified="2019-05-08" version="1">MYEGQSLFHDWIVTPLPLSSLSPPSPSLSPSHFLFVFVSFSFSFFLPSRLPLLFLSLASLSFSFSLSLPSPSLSPSLLSPSHFIFVSVSFSFSFSLLSRLPLPFLSLASLPFSFSLSLPSPSLSPSHFPPLSSSSPSPSLFSLVSLSFTFFLWPPSPLSLSHFPLLFLPLTSLSSFFLSLPSRLRLLLSSLLSPSPSLSSSGLLLLFLSLTSLSSFSLSLPSPLSPSHFLSSSSHFLLVSVSFSLLSCLPLLHFLPLASLSSFSHSLLSPLSPSHFLLASFSFSLSLPSGFPLLFLPLLLFLPHSSLSFSFSLSLPYCQPLLHFLTLSLPSSLSLSHFPLLHFLPLTSPLFLFLPLASLSLLSRLPLLILSFSCTLSPPTSSPYLLPFLVPLLPSLISHSFCLLSLFCYVLDFRFPLLVPSFSPLYPFTSLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB44</accession>
    <name>A0A423UB44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oplophorus-luciferin 2-monooxygenase non-catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004448</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000159">
        <property type="protein sequence ID" value="ROT85893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB44"/>
    <dbReference type="STRING" id="6689.A0A423UB44"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF96">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019333323" evidence="4">
        <location>
            <begin position="43"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT85893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="40175" checksum="8C2427220FD913AB" modified="2019-05-08" version="1">MSLLDAPINTEHPESGPQCPEGKMAGLHRLLALLALALGTVAVSVAEEKAKDADLRSLPCPDPQDISPCVCTVDVQHNMDIDCSQVESEDQLARVFSSNIPFPKFNKLVIYRNPHLTVLRNGDLGPASFQIIEMTDGVLEEVQDGALSMSYSTATRIDLQRNRLSKFPFHEIPSFTALTTLWLSGNSLPEFPLITSDSLTNIGLNFNYFGEIPLNGFQGVKNVNIIDVDGNGITTIVPGTFTDLPHLRYLFLFSNRLSEIPAGAIEFNGNGFLFLDQNNISKIAVGAITGLGDGEVHLNENSLTVLEEDVFGAFLSAGATLEIDDNPLGCGCEIAWLVTNSAYMSLISPGASCYDGELLANLDPTIYEDFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVF3</accession>
    <name>A0A3R7LVF3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quaking-B protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVF3"/>
    <dbReference type="STRING" id="6689.A0A3R7LVF3"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF125">
        <property type="entry name" value="KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="215" mass="23328" checksum="EEE296BB06AB1898" modified="2019-04-10" version="1">MRDKKKEEQNRGKPNWEHLNEELHVLITVEDTENRAKLKIQRAIEEIRKLLVPSADGEDELKKRQLMELAIINGTYRDSSSKNAEFEALGHLAGEAPRLITPGMTLPSPLRTTTPLGGPPLIMPARIHVPTSNALINGTGNAGMPPPLIAASDASASLLYAAPYAAAAEYAANYAALTSPLLTEYPPDAAGVAAKQRRHLGQAREHPYQRTGTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXC9</accession>
    <name>A0A3R7LXC9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cysteine string protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_014914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002864">
        <property type="protein sequence ID" value="ROT67027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXC9"/>
    <dbReference type="STRING" id="6689.A0A3R7LXC9"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061177">
        <property type="term" value="C:type Is terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900073">
        <property type="term" value="P:regulation of neuromuscular synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000017">
        <property type="entry name" value="dnaJ homolog subfamily C member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051434">
        <property type="entry name" value="DnaJ_C_subfamily_member5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44027:SF7">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT67027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="251" mass="27326" checksum="90D0D749E881F251" modified="2019-04-10" version="1">MDRRKLSTTGDSLYETLGLQKQATTDEIKKTYRKLALKYHPDKNPNNPEAAEKFKEINHAHGILSDATKRNIYDNYGSLGLYIAEQFGEENVNTYFLVNSGWCKALFLFCGLITGCYLCCCFCCCFNFCCGKCKPRPPDETGDYHNLNPDQAEGVHTSQPGTSSKKEDLSDDEEGKAAGDQPVTSQPPPSTNPFRTPGAGEPSSGGAQQPVFAMPPPQPSPNPTNPFAMGAGATENTSLNASSQPTYYTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZE1</accession>
    <name>A0A3R7LZE1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RFX-type winged-helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002816">
        <property type="protein sequence ID" value="ROT67383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZE1"/>
    <dbReference type="OrthoDB" id="6375424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="747"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1172"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1233" mass="136309" checksum="A48110215C673970" modified="2019-04-10" version="1">MPSGVIPPRASPAKANTPAAGASACPWGKPPQGRKRLGKQERGRQGRRRRTGVRLEPRLALGPRGLLYDSATGSVRVLRATDLHTSHIPLGNGGTRTPRTHGSSKDSRPRFPCVRCQWENRWIMSGYIPTWRSVCEQWIQEALEEKEGEVTPVYVLYNAYLKDNPDRYLDIAQFGKILKSRFKNRKCRRGKQGAQIYVYKNVIIKPKAASAVSQEAQQGCNLKDQSFDHFSSSDYGLFNGTQSIADPFGKLGLTEPSSSKLLPPDGFCSVKYGSFNDRQSIPGHAQADMTPRLHSGASSANSIMEETSSPLDLRLPTVLARRKLLSSNPCEHSNYKNTKNSKTNVQDVLENQYHNREEDDRSVCSSLSELSSLVKDSDGNSEEGENLHDSVDKSSDFVLADKHVTASSSKYHNEYVFYNRDDISPKKSMLLDVEVKDIEVEEESCLHLDTDQTDTKSIIENYFRDDSQSIESDKQSNVKMMEDHVVFRLEGEELQEIAPIEFSEEPVREEARNAPRSIEGQTAAKVDSLSRTATETNRMALGRRWVDSNLRDQPGKRTFPWEIAAAYARDHPEEPLTDTNFAVLIRSKFPSRRKKMNHGPKTFYYYQDLELTNPSQLPNTSPILRETTPEGQVLAPNVPAILMSGDGGAPVAVLNPPAESVFTMNGKPYVSLKIVDLPSNTSSAGPSNSKRQRTRSYEVVPNCTIQNEAPGESIVNHTRNARVLESGSGAPDKSSNDMQITVQNLPEDDGMFSQGTASPEHPVRDQSISGDEGMFSQGTASPEHPVRDQSLSGDEGMFSQGTASPEHPVRDQASVEVKGCSVKGVRDQSLSGAEGMFSQGTASPEHPVRDQSLSGGEGMFSQGTASPEQEMASQGTARTLRDQSLSGDDFSQGTASPEQPVRDRRDTRDDGMFRKDTAPPERPVADVSPSAFSQNLVDAIKAEPMDTETDLLLDIVPEDVKTNPVLMKMDMAVSDYIHGEMFNEIYTGSGLSEAVRARRLEATIYRSNPAVSYGEPPSPSSETNSYACQTSSRFIESSKTLTYSKVTSLLRHHQTCQGLGCSYSSDLCLTLRAMYTHITIFSHRCQVWGHFTDLVGRHARSCRQRDCQLAFCLYMKHELHLTNAGAMSDDDEEERDDLRKEFDRCESHGPHDARLHCGHLPRVQIPLGEKVSQEYPPQGRGREDAGVPPQGRGRETHPSHGGTGSPGVAGAARSESLFRHTHYKCSKCNCGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZW5</accession>
    <name>A0A3R7LZW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003434">
        <property type="protein sequence ID" value="ROT63486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZW5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="55442" checksum="AA485E71C0C54936" modified="2019-04-10" version="1">MPQVRLPSNGIFSPFLSVLSPARFPSAPVYLHGNLLNLLSQHRRRPSCCASEQRHHRSLLFASFSLYCSRLPCFTIAIAVVLSYVVLSLRPCFSLLGGWHEANTWSISTPACSLPPPSPPQPAPPPPSPDIKRLMRDSRTCQLTCNTYNPLTLPTGGMIFLFKIPPDLCHVLYIPPFVDFAMLVVALVLFSPCVRFVCSFGPKLCIIFTVCSLCSETVSPPLPSSGNGNRADDSKINLTLTQPLFPARFYPKPAGRILDTKFPFRDSGLPADSPYLRSLANNTSLTPPSPSFSPSPSPLLLLLLLSSSSGSSSSPPPPPTFSHQLPKTYTQEPAAESSPSHGSYDTTPKKSYDSTTSTTERSYNSTPEISYDSTTSTAKGSHGTRRPPRKKKPRQRKTTDDQNDGEKPRPSDLHDLRKPWTTPTTEESYDPTTSATDRSPDSTTSTTQGCHDPPTSTTSRSQCEEGGRGPTLPAHPLTPVNTPTFLTDPAPTSLQNRMNNLALYIATAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M153</accession>
    <name>A0A3R7M153_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative T-related protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_011720</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002483">
        <property type="protein sequence ID" value="ROT70016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M153"/>
    <dbReference type="STRING" id="6689.A0A3R7M153"/>
    <dbReference type="OrthoDB" id="7442607at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001708">
        <property type="term" value="P:cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20192">
        <property type="entry name" value="T-box_TBXT_TBX19-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.820:FF:000002">
        <property type="entry name" value="T-box transcription factor Brachyury"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.820">
        <property type="entry name" value="Transcription factor, T-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046360">
        <property type="entry name" value="T-box_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036960">
        <property type="entry name" value="T-box_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002070">
        <property type="entry name" value="TF_Brachyury"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001699">
        <property type="entry name" value="TF_T-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018186">
        <property type="entry name" value="TF_T-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11267">
        <property type="entry name" value="T-BOX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11267:SF106">
        <property type="entry name" value="T-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00907">
        <property type="entry name" value="T-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00938">
        <property type="entry name" value="BRACHYURY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00937">
        <property type="entry name" value="TBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00425">
        <property type="entry name" value="TBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01283">
        <property type="entry name" value="TBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50252">
        <property type="entry name" value="TBOX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="T-box" evidence="9">
        <location>
            <begin position="41"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="406"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT70016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="537" mass="57749" checksum="F0D22B66C79B610A" modified="2019-04-10" version="1">MLKTESVRKLLTTEGCSKVKTEALQQQHSGAASGVEPTVVLEDRDLWTRFQVLTNEMIVTKSGRRMFPVVKVSISGLDPSAMYSILLEFVQIDNHRWKYVNGEWVAGGKPEVAPSSAVYIHCDSPNFGNHWMKEPVSFAKVKLTNKTNGNGQIMLNSLHKYEPRLHVVQVGAEQRTISCHAFPECQFIAVTAYQNEEVTALKIKHNPFAKAFLDSKERPELQSQRDIMASYPQPHHQQYGWYMGGGVCGGGVAYGQTPPTMGLASTPASLSSRIAMRNHRVVPYTSPTPRAARTPPVNAVAQQQAAVGSYGLAGLAAEWRQQPWGHHHQPSVTGAPATPATPAHYQWAGLQGGYAHHPHHHGSGLYQSYQQPGVVGMGLANAATGAVPAHPAQHAQRSPQEALTPMGVYSDTSVPQGYTDNRSSPTYDDSVHSVGANTGVYGSSRLHESPEHNSTGGGSPNMFILPDLGYPSGLAAAHSDLARIKGENLADSLSVYSTTSPSAYSTTSPAAYSTTSPTAYSAAPLHAWSPLSPPACM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3S3</accession>
    <name>A0A3R7M3S3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Aminopeptidase</fullName>
            <ecNumber evidence="21">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">C7M84_009601</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="26 27" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="19 21">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="19 21">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 21">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="21"/>
    <dbReference type="EMBL" id="QCYY01002214">
        <property type="protein sequence ID" value="ROT72064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3S3"/>
    <dbReference type="STRING" id="6689.A0A3R7M3S3"/>
    <dbReference type="OrthoDB" id="510539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000008">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000012">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 21 26" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="11 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="16 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 19 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15 21" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="7 21" id="KW-0645">Protease</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12 19 21" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="25">
        <location>
            <begin position="128"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="23">
        <location>
            <begin position="359"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="24">
        <location>
            <begin position="663"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="24">
        <location>
            <begin position="859"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="22">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="20">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="ROT72064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="987" mass="112556" checksum="2EDC7B86C3642F3C" modified="2019-04-10" version="1">MSGSSREVLAMETSHPDHVISFGKKKGCYVSRCVAALLGVFFLSGMVATGLLVYYYAPHIRDSQRESLILQKPVVPLHKSLPPPTRRPSATSTTTEALRPTVQPPTTSATAAPAAEALDVRLPTALRPLHYLIKLQPFINGNFSILGYMEVEMEVLEPTSNITLHIADIITHNDTVTVAASGDSGPSIRIKRHQYDHDRQFYIAQLDQQLEKNKKYVLSMEFLGYLNDQLRGFYRSTYKDEDGSDKMLAVTQFQATDARRAFPCFDEPEMKATFEVSLAREENMSSISNMPIKETLPVQNQEGWVWDHYHRSVPMSTYLVAFVVSDFANLKSRANENTFFRVWARESAIQQAEYAGQVGPMILNHFEKYFSMPYPLPKQDMIAIPDFSAGAMENWGLITYRETAMLYDPVVSAASNKQYVVAVVAHELAHQWFGNIVTPSWWTDLWLNEGFASYVEYIGINHVEPKWQVMEQFVLREVQEVFGLDCLESSHPISIPVGHPDEIGQIFDRISYGKGASIIRMMNHFLTEVTFRRGLRNYLDAFKYSTAEQDDLWEYLTAVAHQDGTLPRGLTVKMIMDTWTLQMGYPVVKVTRGPDGTSAVVSQERFLLVRSENSSDTHDYKWWVPLTYTTQSEANFNQTQAMVWMKDSEAQISLSSLPPRDQWVIFNLQETGYYRVNYDDHNWGLLIQQLRNDHEVISTINRAQIIDDAMNLAKAGQITYETALSVYTYLSKETEYVPLAAAINNLGYLRSMFVRAGGYGSLRSYLLDILVPLYESVGFEDSPDDPLLDQYKRTKALSWACLLGHQHCLDSASALYRTWMANPTNDSIISPNLKSTVYCRAIAEGGEAEWNFAWHKYLKYLEMAFTPDSGIRKQDAYRVFGAVAKNVVGRPLAWNYLQNEWDKIYDFYGKAKPHFIKYATGGFNTEQHLKEVEHFRKEHEHHLGSASRTVEQVIERTKNNIAWMKTNYDVIVKWLDANGYSTKLSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4K4</accession>
    <name>A0A3R7M4K4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4K4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="214"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="695" mass="72807" checksum="991C5CAEA7921908" modified="2019-04-10" version="1">MDVGVTSVSPHPPSTSIPPSSLAPGEALARHSPLAHHHLSLSHATHHSLTTTLSLLLLSPRGSPSTPLTTRSPPLSPPSPILSPPGKPSTPLTTLTHSLSSVTNPEPPGEALAHSPLTTLSPPPRGSPSTPLTPHHHSLSSVTNPEPPGEALARHSPLAHHHSLSSVTNPEPPGEALARHSLTHSPPLSLSSPILSPRGSPSTPLTTPHHHSLSSHATHTLTTTLSPPSPILSPRGSPSTPLTTPHHHSLSPPSPILSPRGALARHSPLTHHHSLSSVTNPEPRGSPSTPLTTHSHHSLSSVTNPEPPGEALARHSPLAHHHSLSSVTNPEPPGKPLARHSPLAHTTLSPPSPILSPPGTLARHSHSLTTTLSLLPPRGPPRHTHSSPPLSLSHATPHSLTPLSLLLTNPEPPGETLARHSTLAHHTNPEPPGETLARHSTLAHHHSLSSVTNPEPPGETLARHSTLAHHHSLSSHATPHSLTTTLSPPPILSPRETLARHSHTHSPPLSLLLTNPEPPGETLAPTPHSLTTTLSPPTPHSTLTTTTLSPPSPILSPPGEPLARHSTLTHHHSLSPPTPLHTHSPPLSLLLTNPEPPGETLARHSTLTHHHSLSSITNPEPPGETLARHSTLTHHHSLSSITNPEPPGETLARHSTLLTTTLSPLTNPEPPGETLARHSTLSHHHSPILSPPGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6P7</accession>
    <name>A0A3R7M6P7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fatty acid synthase</fullName>
            <ecNumber evidence="5">1.1.1.100</ecNumber>
            <ecNumber evidence="2">1.3.1.39</ecNumber>
            <ecNumber evidence="6">2.3.1.41</ecNumber>
            <ecNumber evidence="4">2.3.1.85</ecNumber>
            <ecNumber evidence="3">3.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="69" type="ORF">C7M84_013249</name>
    </gene>
    <organism evidence="69 70">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="69 70" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="69">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="69 70" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="69">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="32">Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="39">
            <text>(2E)-butenoyl-[ACP] + NADPH + H(+) = butanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9627"/>
            <dbReference type="Rhea" id="RHEA-COMP:9628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78453"/>
            <dbReference type="ChEBI" id="CHEBI:78454"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="39">
            <dbReference type="Rhea" id="RHEA:41813"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="62">
            <text>(2E)-decenoyl-[ACP] + NADPH + H(+) = decanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41864"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="Rhea" id="RHEA-COMP:9640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
            <dbReference type="ChEBI" id="CHEBI:78468"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="62">
            <dbReference type="Rhea" id="RHEA:41865"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="46">
            <text>(2E)-dodecenoyl-[ACP] + NADPH + H(+) = dodecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9643"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="ChEBI" id="CHEBI:78472"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="46">
            <dbReference type="Rhea" id="RHEA:41881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="41">
            <text>(2E)-hexadecenoyl-[ACP] + NADPH + H(+) = hexadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41912"/>
            <dbReference type="Rhea" id="RHEA-COMP:9651"/>
            <dbReference type="Rhea" id="RHEA-COMP:9652"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78481"/>
            <dbReference type="ChEBI" id="CHEBI:78483"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="41">
            <dbReference type="Rhea" id="RHEA:41913"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="42">
            <text>(2E)-hexenoyl-[ACP] + NADPH + H(+) = hexanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41832"/>
            <dbReference type="Rhea" id="RHEA-COMP:9631"/>
            <dbReference type="Rhea" id="RHEA-COMP:9632"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78458"/>
            <dbReference type="ChEBI" id="CHEBI:78459"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="42">
            <dbReference type="Rhea" id="RHEA:41833"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="55">
            <text>(2E)-octadecenoyl-[ACP] + NADPH + H(+) = octadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41928"/>
            <dbReference type="Rhea" id="RHEA-COMP:9655"/>
            <dbReference type="Rhea" id="RHEA-COMP:9656"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78489"/>
            <dbReference type="ChEBI" id="CHEBI:78495"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="55">
            <dbReference type="Rhea" id="RHEA:41929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="48">
            <text>(2E)-octenoyl-[ACP] + NADPH + H(+) = octanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41848"/>
            <dbReference type="Rhea" id="RHEA-COMP:9635"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78462"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="48">
            <dbReference type="Rhea" id="RHEA:41849"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="57">
            <text>(2E)-tetradecenoyl-[ACP] + NADPH + H(+) = tetradecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41896"/>
            <dbReference type="Rhea" id="RHEA-COMP:9647"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78475"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="57">
            <dbReference type="Rhea" id="RHEA:41897"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>(3R)-hydroxybutanoyl-[ACP] = (2E)-butenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41808"/>
            <dbReference type="Rhea" id="RHEA-COMP:9626"/>
            <dbReference type="Rhea" id="RHEA-COMP:9627"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78451"/>
            <dbReference type="ChEBI" id="CHEBI:78453"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="31">
            <dbReference type="Rhea" id="RHEA:41809"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>(3R)-hydroxydecanoyl-[ACP] = (2E)-decenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41860"/>
            <dbReference type="Rhea" id="RHEA-COMP:9638"/>
            <dbReference type="Rhea" id="RHEA-COMP:9639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78466"/>
            <dbReference type="ChEBI" id="CHEBI:78467"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="26">
            <dbReference type="Rhea" id="RHEA:41861"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>(3R)-hydroxydodecanoyl-[ACP] = (2E)-dodecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41876"/>
            <dbReference type="Rhea" id="RHEA-COMP:9642"/>
            <dbReference type="Rhea" id="RHEA-COMP:9643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78470"/>
            <dbReference type="ChEBI" id="CHEBI:78472"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:41877"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="30">
            <text>(3R)-hydroxyhexadecanoyl-[ACP] = (2E)-hexadecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41908"/>
            <dbReference type="Rhea" id="RHEA-COMP:9650"/>
            <dbReference type="Rhea" id="RHEA-COMP:9651"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78480"/>
            <dbReference type="ChEBI" id="CHEBI:78481"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="30">
            <dbReference type="Rhea" id="RHEA:41909"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41828"/>
            <dbReference type="Rhea" id="RHEA-COMP:9630"/>
            <dbReference type="Rhea" id="RHEA-COMP:9631"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78457"/>
            <dbReference type="ChEBI" id="CHEBI:78458"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:41829"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>(3R)-hydroxyoctadecanoyl-[ACP] = (2E)-octadecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41924"/>
            <dbReference type="Rhea" id="RHEA-COMP:9654"/>
            <dbReference type="Rhea" id="RHEA-COMP:9655"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78488"/>
            <dbReference type="ChEBI" id="CHEBI:78489"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="29">
            <dbReference type="Rhea" id="RHEA:41925"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>(3R)-hydroxyoctanoyl-[ACP] = (2E)-octenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41844"/>
            <dbReference type="Rhea" id="RHEA-COMP:9634"/>
            <dbReference type="Rhea" id="RHEA-COMP:9635"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78461"/>
            <dbReference type="ChEBI" id="CHEBI:78462"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:41845"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>(3R)-hydroxytetradecanoyl-[ACP] = (2E)-tetradecenoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:41892"/>
            <dbReference type="Rhea" id="RHEA-COMP:9646"/>
            <dbReference type="Rhea" id="RHEA-COMP:9647"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78474"/>
            <dbReference type="ChEBI" id="CHEBI:78475"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="28">
            <dbReference type="Rhea" id="RHEA:41893"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="43">
            <text>3-oxobutanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxybutanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41804"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="Rhea" id="RHEA-COMP:9626"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="ChEBI" id="CHEBI:78451"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="43">
            <dbReference type="Rhea" id="RHEA:41805"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="37">
            <text>3-oxodecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41856"/>
            <dbReference type="Rhea" id="RHEA-COMP:9637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9638"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78464"/>
            <dbReference type="ChEBI" id="CHEBI:78466"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="37">
            <dbReference type="Rhea" id="RHEA:41857"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="58">
            <text>3-oxododecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxydodecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41872"/>
            <dbReference type="Rhea" id="RHEA-COMP:9641"/>
            <dbReference type="Rhea" id="RHEA-COMP:9642"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78469"/>
            <dbReference type="ChEBI" id="CHEBI:78470"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="58">
            <dbReference type="Rhea" id="RHEA:41873"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="59">
            <text>3-oxohexadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9650"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78478"/>
            <dbReference type="ChEBI" id="CHEBI:78480"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="59">
            <dbReference type="Rhea" id="RHEA:41905"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="50">
            <text>3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41824"/>
            <dbReference type="Rhea" id="RHEA-COMP:9629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9630"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78456"/>
            <dbReference type="ChEBI" id="CHEBI:78457"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="50">
            <dbReference type="Rhea" id="RHEA:41825"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="34">
            <text>3-oxooctadecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41920"/>
            <dbReference type="Rhea" id="RHEA-COMP:9653"/>
            <dbReference type="Rhea" id="RHEA-COMP:9654"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78487"/>
            <dbReference type="ChEBI" id="CHEBI:78488"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="34">
            <dbReference type="Rhea" id="RHEA:41921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="60">
            <text>3-oxooctanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyoctanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41840"/>
            <dbReference type="Rhea" id="RHEA-COMP:9633"/>
            <dbReference type="Rhea" id="RHEA-COMP:9634"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78460"/>
            <dbReference type="ChEBI" id="CHEBI:78461"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="60">
            <dbReference type="Rhea" id="RHEA:41841"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="54">
            <text>3-oxotetradecanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxytetradecanoyl-[ACP] + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:41888"/>
            <dbReference type="Rhea" id="RHEA-COMP:9645"/>
            <dbReference type="Rhea" id="RHEA-COMP:9646"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78473"/>
            <dbReference type="ChEBI" id="CHEBI:78474"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="54">
            <dbReference type="Rhea" id="RHEA:41889"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="36">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="36">
            <dbReference type="Rhea" id="RHEA:17399"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="27">
            <dbReference type="Rhea" id="RHEA:13098"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="51">
            <text>a 2,3-saturated acyl-[ACP] + NADP(+) = a (2E)-enoyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22564"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.39"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="51">
            <dbReference type="Rhea" id="RHEA:22566"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="49">
            <text>a fatty acyl-[ACP] + malonyl-[ACP] + H(+) = a 3-oxoacyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="49">
            <dbReference type="Rhea" id="RHEA:22837"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="33">
            <text>acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H(+) = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP(+).</text>
            <dbReference type="EC" id="2.3.1.85"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="44">
            <text>acetyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxobutanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41800"/>
            <dbReference type="Rhea" id="RHEA-COMP:9621"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78446"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="44">
            <dbReference type="Rhea" id="RHEA:41801"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="61">
            <text>butanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41820"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9628"/>
            <dbReference type="Rhea" id="RHEA-COMP:9629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78454"/>
            <dbReference type="ChEBI" id="CHEBI:78456"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="61">
            <dbReference type="Rhea" id="RHEA:41821"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="56">
            <text>decanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41868"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9641"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78468"/>
            <dbReference type="ChEBI" id="CHEBI:78469"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="56">
            <dbReference type="Rhea" id="RHEA:41869"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="40">
            <text>dodecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxotetradecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41884"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="Rhea" id="RHEA-COMP:9645"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78473"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="40">
            <dbReference type="Rhea" id="RHEA:41885"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="53">
            <text>hexadecanoyl-[ACP] + H2O = hexadecanoate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:41932"/>
            <dbReference type="Rhea" id="RHEA-COMP:9652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:7896"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78483"/>
            <dbReference type="EC" id="3.1.2.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="53">
            <dbReference type="Rhea" id="RHEA:41933"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="45">
            <text>hexadecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctadecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9653"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78483"/>
            <dbReference type="ChEBI" id="CHEBI:78487"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="45">
            <dbReference type="Rhea" id="RHEA:41917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="35">
            <text>hexanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxooctanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9633"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78459"/>
            <dbReference type="ChEBI" id="CHEBI:78460"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="35">
            <dbReference type="Rhea" id="RHEA:41837"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="52">
            <text>holo-[ACP] + acetyl-CoA = acetyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41788"/>
            <dbReference type="Rhea" id="RHEA-COMP:9621"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78446"/>
            <dbReference type="EC" id="2.3.1.38"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="52">
            <dbReference type="Rhea" id="RHEA:41789"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="63">
            <text>octanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxodecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41852"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78464"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="63">
            <dbReference type="Rhea" id="RHEA:41853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="47">
            <text>tetradecanoyl-[ACP] + H2O = tetradecanoate + holo-[ACP] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30123"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30807"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
            <dbReference type="EC" id="3.1.2.14"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="47">
            <dbReference type="Rhea" id="RHEA:30124"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="38">
            <text>tetradecanoyl-[ACP] + malonyl-[ACP] + H(+) = 3-oxohexadecanoyl-[ACP] + holo-[ACP] + CO2</text>
            <dbReference type="Rhea" id="RHEA:41900"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9648"/>
            <dbReference type="Rhea" id="RHEA-COMP:9649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78477"/>
            <dbReference type="ChEBI" id="CHEBI:78478"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="38">
            <dbReference type="Rhea" id="RHEA:41901"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="caution">
        <text evidence="69">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="5"/>
    <dbReference type="EC" id="1.3.1.39" evidence="2"/>
    <dbReference type="EC" id="2.3.1.41" evidence="6"/>
    <dbReference type="EC" id="2.3.1.85" evidence="4"/>
    <dbReference type="EC" id="3.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002654">
        <property type="protein sequence ID" value="ROT68596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A3R7M6P7"/>
    <dbReference type="STRING" id="6689.A0A3R7M6P7"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004313">
        <property type="term" value="F:[acyl-carrier-protein] S-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141148">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004312">
        <property type="term" value="F:fatty acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016297">
        <property type="term" value="F:fatty acyl-[ACP] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05195">
        <property type="entry name" value="enoyl_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08954">
        <property type="entry name" value="KR_1_FAS_SDR_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00833">
        <property type="entry name" value="PKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000013">
        <property type="entry name" value="Fatty acid synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000015">
        <property type="entry name" value="Fatty acid synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000209">
        <property type="entry name" value="Polyketide synthase Pks12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="entry name" value="Polyketide synthase dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049391">
        <property type="entry name" value="FAS_pseudo-KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049552">
        <property type="entry name" value="PKS_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049900">
        <property type="entry name" value="PKS_mFAS_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050091">
        <property type="entry name" value="PKS_NRPS_Biosynth_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43775:SF7">
        <property type="entry name" value="FATTY ACID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21149">
        <property type="entry name" value="FAS_pseudo-KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21089">
        <property type="entry name" value="PKS_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52019">
        <property type="entry name" value="PKS_MFAS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="17" id="KW-0007">Acetylation</keyword>
    <keyword evidence="21" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="20" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="22" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="19" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-0521">NADP</keyword>
    <keyword evidence="18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="70" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0702">S-nitrosylation</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="67">
        <location>
            <begin position="40"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="PKS/mFAS DH" evidence="68">
        <location>
            <begin position="897"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="66">
        <location>
            <begin position="2026"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal hotdog fold" evidence="64">
        <location>
            <begin position="897"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal hotdog fold" evidence="64">
        <location>
            <begin position="1043"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="65">
        <location>
            <begin position="2101"/>
            <end position="2134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="65">
        <location>
            <begin position="2104"/>
            <end position="2130"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for dehydratase activity" evidence="64">
        <location>
            <position position="932"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for dehydratase activity" evidence="64">
        <location>
            <position position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00023373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00023388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00023394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00023398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00023399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00023401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00023402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00023442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00044883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="ARBA" id="ARBA00047300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="35">
        <source>
            <dbReference type="ARBA" id="ARBA00047394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="36">
        <source>
            <dbReference type="ARBA" id="ARBA00047400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="37">
        <source>
            <dbReference type="ARBA" id="ARBA00047440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="38">
        <source>
            <dbReference type="ARBA" id="ARBA00047451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="39">
        <source>
            <dbReference type="ARBA" id="ARBA00047500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="40">
        <source>
            <dbReference type="ARBA" id="ARBA00047578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="41">
        <source>
            <dbReference type="ARBA" id="ARBA00047810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="42">
        <source>
            <dbReference type="ARBA" id="ARBA00047897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="43">
        <source>
            <dbReference type="ARBA" id="ARBA00047953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="44">
        <source>
            <dbReference type="ARBA" id="ARBA00047961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="45">
        <source>
            <dbReference type="ARBA" id="ARBA00048051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="46">
        <source>
            <dbReference type="ARBA" id="ARBA00048281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="47">
        <source>
            <dbReference type="ARBA" id="ARBA00048289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="48">
        <source>
            <dbReference type="ARBA" id="ARBA00048420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="49">
        <source>
            <dbReference type="ARBA" id="ARBA00048506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="50">
        <source>
            <dbReference type="ARBA" id="ARBA00048571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="51">
        <source>
            <dbReference type="ARBA" id="ARBA00048650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="52">
        <source>
            <dbReference type="ARBA" id="ARBA00048691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="53">
        <source>
            <dbReference type="ARBA" id="ARBA00048704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="54">
        <source>
            <dbReference type="ARBA" id="ARBA00048935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="55">
        <source>
            <dbReference type="ARBA" id="ARBA00049019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="56">
        <source>
            <dbReference type="ARBA" id="ARBA00049109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="57">
        <source>
            <dbReference type="ARBA" id="ARBA00049171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="58">
        <source>
            <dbReference type="ARBA" id="ARBA00049263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="59">
        <source>
            <dbReference type="ARBA" id="ARBA00049414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="60">
        <source>
            <dbReference type="ARBA" id="ARBA00049422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="61">
        <source>
            <dbReference type="ARBA" id="ARBA00049449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="62">
        <source>
            <dbReference type="ARBA" id="ARBA00049521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="63">
        <source>
            <dbReference type="ARBA" id="ARBA00049533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="64">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="65">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="66">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="67">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="68">
        <source>
            <dbReference type="PROSITE" id="PS52019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="69">
        <source>
            <dbReference type="EMBL" id="ROT68596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="70">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2431" mass="261122" checksum="885D902561161161" modified="2019-04-10" version="1">MPAYAETLTDAKPSTHLPTHPELLTQLPGKTKVADGARCQESVVVSGMSGKFPESSSVEEFARNLYSGVDMVTEDDRRWTPGIHGLPRRSGKIPDLAHFDSAFFSVSPRQAHKMDPQLRLLLELTHEAILDAGMNPSELRGRRVGVYVGVSSSESEEAWTADPAQVTGYALTGCCRAMFPNRISYTFDFKGPSYAIDTACSSSMVALQVAWTAIMEGEIEAAVVGGTNLTLKPQNSMQFNSLNMLAADGKCKSFDCSGNGYVRSEAAVVIFLQRAADSRRVYAHVTHARANTDGHKGEGVTFPSGAVQKNLLQEVYSLAGVSPSDVSYVEAHGTGTKAGDPQEVNALSDVFCNGRSSPLLMGSVKSNMGHAEPASGLCSIVKVLLAMQRREIAGNLHFTSPNTEIPALSDGRIKVVSENTPWPGGYAAVNSFGFGGANVHVLLRSPNTPVQSSSGPSRPVLIPTTQRICPTTKEIISSDCHFATSGEDENNASEDKVPTGIPRLVVTAGRTEDAVRTLLEGVKERATPALCGLLDKLSDMPTNSLPARGYAIVDAEREILGVSSVPAASRPLWLVFSGMGSQWTSCGRAFFRFPVFASTIRRCHAALMPLGLNLTEILTSEDPNVMATTAASFSTIAAMQVGLVDLLKHLGINEYAGLVGHSVGELGCAYADGTLTAEQTVLAAYWRGRAVQEAVLPVGAMAAVGLSAEEAERWVEDGVVVACHNAHDSVTISGPKEATERVMEKITAEGIFCRGVRSENVIPRALPRSSRWVSTSVPESESASPEASKASAQYLVNNLLSPVLFAEALEKIPQEAVVVEVSPHGLLQAILRRSLPKAVPIPLIRKDAKCTMLHFLESLGKIYANGVFVDVGSIYPPLPSPVPVSTPSIASLVRWDHSQEWDVARFSSSPAGSDYEVKVDLDSEEHRYLEGHTIDGRVIFPATGYMVLAWQALCRLQGSNWQETPVTFSDVILHQATVLSSSSGSSSSTTTLVVRILPTKGEFEVVVSGSVAASGRIHMGVEDSAEGKTLLHFLKESKASDHEKRLQQQDVYKELRLRGYQYGGIFQGILHADIKGTSGSLQWRDNWVSFIDTMLQFSLVGAKQRGLMLPTRIRKVTVDPAVLHSNVTVEEDVTKVPIHHNPHVGATVCQGVIIQGLKATLAPRRPTQDRPVLQSYQFVPLQLPVDHPVSAKVTEEASLGLLVDLVIENLGTRTLKVVENGSTSPTIGLGVMSAVDTHAQLKVEYTLTNPSLEKEELDRLVSAGATVKEDLVSVMSKPPHLFILHQDVEAKILDTLKEGTFLMTNADVAQMLKEQGYLSIATIARTGVVLLRKPLSPVPHSTLTISVNDKEFSWVMALKEKLAVSIKENLWLLSSHEPTSGILGLVNCLRREPEGERIRCIFAPDGKAEVDTDVLARDLALNVLEGQAWGTYRHIPLMKLEHQPSEHALLNVATRGDLASLTWFQMASPELSPNENMLVCDVLYAPLNFRDVMLATGKLPPDALPGDLAMKECILGLEFAGMERERRVMGLVAAGGLATTVKADPLLTWTVPQSWSLQEAATVPVVYATAYYALVVRGGLREGETVLIHAGSGGVGQAAISIALARSCTVYTTVSSAQKRAVLQKRFPQLKDENFANSRDGSFEFDVLERTNGQGVDVVLNSLAGDLLQASVRCLKEHGRFLEIGKADLSNNTALGMAIFLKNVTFHGILLDSLFDGSTEERARLNKLVIDGLESGVVTPLPHTLFTRDSAEDAFRYMATGKHIGKVVLEIKPEEPKADYSLVPAVPRMTAHSNMVYVITGGMGGLGLELAGWLITRGAKKLVLTSRRGITTGYQSLCVHRWRNAGVNVRVLTQDASTPEGAAKLLKEAATEGPVGGIFHLAMVRSDALLDNQDSTTFRTVNHVKGDGAVAIDEASRKLCPDLHLWVAFSSVACGKGNAGQTNYGWANSVCERVVESRVRAGLPGVAIQWGGVGDVGVLADTLGDVEVAGTKPQSVRSVLECLDVLLLGSSSVVASVCLATKKSGADGGQKGASLVKSVANILGVKDVSKAPMDVTLADLGLDSLMSVEVKQTLEREADIVLSAAQVRELTLRILQDMDAQGGAKTQNASEGSQNTSDSSKTPSSEQPQVAPQPWLSLPLIPDARVTVLKETGTQPPLFLAAPIQGSALPLVEVAQDLDRPVYGLQYPSDLPHTSISEMAAALVKELQERHPSGDFAIGGYSFGTGVALEMVRQLEAAGRAPTSIVLLDGSQSYVSGIIDTYKSRIVSGSAKEEFSPQEQVEMLLVFAMQFISAESSILKKALLGLRSWEERVNHVAELVTDSRARLGNSTDPDDHNKAVQAAELLYKRLVAGERHSAAGGLRPPALLIRAKDNPNAAQLGHDYGLSKVMTGPLKIEEVSGTHESFLTGTNGRQVSTLIHSFLQGSQRTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8W8</accession>
    <name>A0A3R7M8W8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative transcription factor Sp5-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_011471</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Sp1 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002447">
        <property type="protein sequence ID" value="ROT70262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8W8"/>
    <dbReference type="OrthoDB" id="6360012at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22541">
        <property type="entry name" value="SP5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000014">
        <property type="entry name" value="Transcription factor Sp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000026">
        <property type="entry name" value="Transcription factor Sp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF29">
        <property type="entry name" value="TRANSCRIPTION FACTOR SP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="185"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="215"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="301"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="344"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT70262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="41194" checksum="BD1189D9592A99A0" modified="2019-04-10" version="1">MYACGTLTESQLPHWSAMSANNAFNSTSNFASFHQQPLPLSPAASHFAHVSTPVSYLQHHYNAIAPPMLSPPRETRHAPKEPHTSSCWNTAAYATPPSHAASTYHFHPHQYASLALGGVAHVSPAVPQSVPSAVTHDAIPHQQSNIAAALLTAHSSLTVRRCRRCRCPNCQDTSRDASAAKKREHVCHVPGCGKLYAKTSHLKAHLLSHSGERPFVCHWIFCNKAFTRSDELQRHLRTHTGEKRFQCEECGKRFMRSDHLNKHVKTHQNRRARLASASPAEGDDVDVELCDDEEFLSVTLPDSPVSETDFQEPNDRRRTEGVRSGHGRRRGPGRRGQGGLEAQDTGQGRSAASNKEVELDHDLIITCSVFIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8Y6</accession>
    <name>A0A3R7M8Y6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001684">
        <property type="protein sequence ID" value="ROT76210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8Y6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="114" mass="12771" checksum="57855AE295CB3012" modified="2019-04-10" version="1" fragment="single">PESGRADFLRQPFAAAARHDPLECVPLVLCAIHADPEELLTPRESAFRRVFRSIFAPEPVPSWAKRYVDASIRGSTKNSTRVCQEAYPACAFSSHQLRKLVDVALETGNYLTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9W7</accession>
    <name>A0A3R7M9W7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ionotropic glutamate receptor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_005401</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001701">
        <property type="protein sequence ID" value="ROT76012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9W7"/>
    <dbReference type="STRING" id="6689.A0A3R7M9W7"/>
    <dbReference type="OrthoDB" id="6380517at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF30">
        <property type="entry name" value="IONOTROPIC RECEPTOR 40A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="10">
        <location>
            <begin position="40"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT76012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="38616" checksum="020C3FBDC5EEB0E8" modified="2019-04-10" version="1">MVFQRANQLTGVWESYTQEFGCRSWAAVVLFVVLCPCVLSLVSRSAPSECTRVTLLDAVTCTLGFLGQQGTSLSFTSAPSRIFFLASFVTTVLLYCHYTSALFSSLAVTANSQPFRDLRGILENGKYRFGFTEGISVENDFKDSSNYLYQQVWQRLVMPPPSGLMHDDVAGLTRVRREKYVHMMDRTNFLYMTTGQCDLEMLPRPLFSYPSGFAFRKRSPYTEVFSRALLGLMDSGVTRKLIETWQPETSVCKSLDVQPLTLTHVFTAFLLIGGGLVLSLIIMAGEILYKNLQESGGVTKREINGKTGDNEIKMMREGGINNDGLRTTNRFTWVDRTRFKKCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAD8</accession>
    <name>A0A3R7MAD8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002304">
        <property type="protein sequence ID" value="ROT71365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAD8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="41114" checksum="9BCBCB558C4589D5" modified="2019-04-10" version="1">MDYPQGRREGAALTKKTRSAGHKGLAAAEANTRTLLLQIFFSASQESGFHGILRGHKAAEAPGPAFQRGSQEDTGEGTQQGAQQRDAAGKRQQGTQQRDAAGKRQQGDAGEMKIGKVSSPAERVLVPGSSLIQHPQAAHFSPPPSSNPRRPSPPPSPQTAPPFQHPKPPFLPPLQHPKTPSPPSTPRRPLPPPLPAPQTALPHLQLPKPPPLPAPQTPTPLQHPKHLPPSLQHPKLPSLPTQPKPTPSSAPKTPSPPPAPQDASPPFQHPNASPPFSTQDAPLAPKTPFHLQHSAHLQHPNVTPPPLQHPRDAPFRRPSPPSSKDAFHHQDAPFQHSFPAPKTPPSPRRHRLYHSDFPNRLIRLHNAVAVSPCCPSDVTGAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC37</accession>
    <name>A0A3R7MC37_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002132">
        <property type="protein sequence ID" value="ROT72589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC37"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="46561" checksum="39B7BB014A19225E" modified="2019-04-10" version="1">MALSLRLPSPSPISSPQPQFPPPAPPAPPQPPPFKPLPTDPSPRPFPSLPQLPPLPQPHPELILTSLHRFPSPQPVPTLDFPPPFRPNYFFLIDSRDSLPLSPTPSSSSLPQPLRVTLRQPPPPPTPLTLSAPTLNLPSPPPLFRLLPPSDSTPREPLPRLYPSPPPLPFPAPSPFPAPSLFPRPLPPSPNPSRYYYYCSFYSIPCGGRGEPKNKRASPCACERSDLHLLPDRLGCGCSFLRGYGWFGLIGIIDFSSFSLPYCFSLSVPLPSSLPPFPDPPPTRFTPSPSLPPPYPLLPPPPPSLLLPPPYPLFPPSLPLTPFSLPPPYPFSLPPPYHLLPPSPLPLFSLPPLTPFSNPPPLLQPSPLPPLQPSPYPLLPPSLPLTPFPSPPLPPPSLPLTPLPSSHFPVPLTLPLLPPPPPPQPTLDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDF6</accession>
    <name>A0A3R7MDF6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001210">
        <property type="protein sequence ID" value="ROT79650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDF6"/>
    <dbReference type="STRING" id="6689.A0A3R7MDF6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="655" mass="73100" checksum="CBED7231B72EE76D" modified="2019-04-10" version="1">MVIAHRCTQFHSPPPIHFISTHCLHPHHSLHAHPLASSTPIRFILRHSLHPHPFASSSAIPFIHTHSLHPPPFSSHNHSLHPPPSFIHTHSPHPSAISLHPHPYPPPFPSSHPFAHPPPFPSSTPIRFILRHSFIHSLHHAIPFTTPHRFILPPFPSSTPIRHPHIFIHTHSPHPPPFLHPHQSPFFITPPHPPPFLSSTPIRPSSAIPFIHTHSPILRHSLHPHPFASSSAIPFIPHPFASILPIPSFHTHSVHPAFASSSTHSLSSTPIRFILRHSLHPQFPSPTIRLILTHSLHPHPFASSSAIPFIHTHSLHPRHHASPIPFIHTHSSSAIPFIHTHSLHPPAIPFIHTHSLILRHSLHPHPFASSSAIPFIHTHSLHPPPFPSSTPIRLILRHSLHPHPFAILRLPHPAISLHPHPFASSSAIPFIHTHSLPQFLAIPFIHPIRLILTPFLHPHHSLHPPPFRTHSLHPPPFIFASSSIPSFHTHSLILRHSLHPTIRFILRPFPFILIPFIHTHIRHSLHPHPFASSSPIPFIHTHSLHPPPFPSSTPIRFILSHSPHPHPSTSSAPIAFIHTYSPHPRSSIPSSTPIRFNPSSSPCSPTPPVTADSQCRQEEAGGAPAPPIAYPDAHKPFQPPPPHNRHAHSPSPPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI87</accession>
    <name>A0A3R7MI87_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">C7M84_024432</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000828">
        <property type="protein sequence ID" value="ROT82406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI87"/>
    <dbReference type="STRING" id="6689.A0A3R7MI87"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF41">
        <property type="entry name" value="INNEXIN INX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="362" mass="42081" checksum="9753DCDC32AE5704" modified="2019-04-10" version="1">MYDVFGSIRGLLKIDCVSIDNNIFRMHYKATMFILVAFSLLVTQKQYFGDPIDCIVEGVDSGIMDTYCWIHSTFTIPSLTGAKVGEEVPHPGIANPNIHGPDDNYQTKHHKYYQWVTLFLYLQAIMFYIPRYLWKIWEGGKVKMLVMQLNSPIVDDDAKRERKQMLVNYFSLNLHNHNFYAFRFFACEVLNFVNVIGQIYFTDRFLGYEFTTYGTRVLQFSEQEIGTRHDPMDEVFPKVAKCTFHKYGASGTVERHDGLCVLPLNIFNEKIYIFLWFWFIIVAVISGVGLLYRLATFTPAFRQILLRTRSRLASSDNVEAISRKCQIGDWFVLYQLAKNMDPLIYKEFITELANKLQGKGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIL6</accession>
    <name>A0A3R7MIL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001514">
        <property type="protein sequence ID" value="ROT77520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIL6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="43422" checksum="DCE67A52DE947A3E" modified="2019-04-10" version="1">MSFVPLPPSLFPPSLRVLLLSPSSLTSSVPLPIPSLFLLLYVFFPSSLPSLRLLSLSLLYSLLLYVFYPSLPPPLRLLPLSLPLNSLHLYVFYPSSPPSLIPPPLRLLPLSLPLYSLLVYQNTCVSFRLFLVCVSLGFRGFRAGEGGQQTRPPELQLSRRRVALVTEIPLGNPSLSPFFFFLHLPSLFNFLCSFFPSPSLPLPLSLSPFFFHSLPSLFLSSSLPFPVLFSVHLPSLPLPLSPFFFRSPSYLFLSPSLPFPVPFSVHLPSIFLFLPPSLVPFPSSLPLLSPSFPLSFSLPCSLSTSHSFSFSLSRSLPSLLPLPSLIPSPSLLLLASSSPSLSLLSTSRFRQIFHSPSQFPILYHCLPPIVIFTVEIPTTITPSFGRLNHLWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJF3</accession>
    <name>A0A3R7MJF3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative diacylglycerol kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022518</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000566">
        <property type="protein sequence ID" value="ROT84294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJF3"/>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.110:FF:000008">
        <property type="entry name" value="Diacylglycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.110">
        <property type="entry name" value="Diacylglycerol kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029477">
        <property type="entry name" value="DAG_kinase_typeI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038199">
        <property type="entry name" value="DGK_typeI_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14513">
        <property type="entry name" value="DAG_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Diacylglycerol kinase type I N-terminal" evidence="2">
        <location>
            <begin position="59"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="315" mass="34441" checksum="0E205137F603084F" modified="2019-04-10" version="1">MSLFPYQCVFTSPYLCSSASCNSSNRNLLLCRYDQGILSRPAAARVSEVRVAVRMSLHWEKLSPAEFQQLQDFSAYSSKKLEDVLKEFTGTGTLSKYSLDGDIDYEGFRQFMDTYLEVDTPEELCRHLFLSFVKRPRPQPVEPKSIKEMAVMSSATACAPITSHNTSGGSISNLATCSVGEAMSGGSGGGGGGTLAEKLHGLTEKFSSLGHNRSDSEASSRTRTGSIGACVHPWSPSRRPTATPTGRWRRAPTPRPRTRRCQGRPPRSPTTRSSSPMGSWKPLSRHLTPPHPPQRLPPPSEISSPLPSLSTRPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKC6</accession>
    <name>A0A3R7MKC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_002265</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IFT172 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001303">
        <property type="protein sequence ID" value="ROT79012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKC6"/>
    <dbReference type="STRING" id="6689.A0A3R7MKC6"/>
    <dbReference type="OrthoDB" id="2186662at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030992">
        <property type="term" value="C:intraciliary transport particle B"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000008">
        <property type="entry name" value="Intraflagellar transport protein 172 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000013">
        <property type="entry name" value="intraflagellar transport protein 172 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056168">
        <property type="entry name" value="TPR_IF140/IFT172/WDR19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056157">
        <property type="entry name" value="TPR_IFT80_172_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722">
        <property type="entry name" value="IFT140/172-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722:SF2">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24762">
        <property type="entry name" value="TPR_IF140-IFT172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23387">
        <property type="entry name" value="TPR_IFT80_172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="IFT80/172/WDR35 TPR" evidence="10">
        <location>
            <begin position="574"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="IF140/IFT172/WDR19 TPR" evidence="11">
        <location>
            <begin position="926"/>
            <end position="1123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1125" mass="128184" checksum="2FBD4B9D31EA7AB3" modified="2019-04-10" version="1">MDATLVVREPLTLAMTLLYLALFFYIYVQLILVLVYGHKRWGEKKVICNKFVQSSQVTCLTWPLEGPIIFGLLEGKVRAANIKSNKSHTLYQTDSYVVSLTPNLRGTAFLAGHADGSVVRYYVSDDPYAEPQGKIISHPVPPYAMAWTNNNIIIAGCDKRIIMYNKSGKIHQQFDYSRDETEREFTTAVTSPSGQALVIGSYDRLRIFDYNTSRGMWDVKANREFQGFYTITALAWKRDGSRLVCGTLCGAVELFDSVLRRTVWKNKWEMTYVGPSQVLVKPLAGSGPFGSRGVILRSQYGFEIHDVRIMGKDRYLVARTNETILLGDLHRNLLSEVHWGAEPGTEKFYFDNENVCMIFSAGELSLVEYGNNDILGSVRTEFMNPHLISVRLNERRQRGIEDNKKMAYLLDLKTICMVDLVFGVTVGQVTHDSRIDWLELNETGTQLLFRDKRQRLLLINVGSLQKTSILNYSTFVQWVPGSDVVVAQSREQLCVWYNIDIPERVTTFQIKGEVVDVERADGRTEVIVQDGVQELSYALDEGLIEFGTAVDDGDFLRAMNYLESLPMTAEAETMWRTLARLTLEGRQLYIAERCFAALGDVSKVRYLQGINHIRQLIQENSGEDGVNHHEVQARLAILDKQFKTAESIYLDYNNLGAAMEMYQELHKWDEAVQLAEVKGHPEVESLRRAHLQWLLETHQEEKAGQMKEAEGDYMAAINMYLKAGMPAKASRLVSSVDELRDDPDLVGRITNALLKVELYEQAGDLYEKVGQPQKAMESYRRGQAYYRAVELARHHFPGEVIKIEEEWGDLLVSNKQADAAISHYIEAGRTLKALEAAISARQWKKAVQIIEVIDDEVSLKPHLLKLGQHFASLNDLRSAEKFYVKGGMYKEAIEMYNQAGEWERAHQLASRHMGADEVAVMYVNQAQVLEGQGKFKEAEKLYISVHEPDLAITMYKKQRQYDQMMRLVREYHPDLVQSTHLHLAGELEQENNYRDAEKHYVAAEDWKAAVNMYRSVDMWEDAYRVAKQHGGANAGKQVAFLWARTLRGDAAVKLLNKFGLLEQCIDYACESMQFEFAFELARTAMKQKVPDIHYKYAMALEDDGKYSEAESEFIQAGKPKEAVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKK8</accession>
    <name>A0A3R7MKK8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dual specificity protein phosphatase 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_022589</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000581">
        <property type="protein sequence ID" value="ROT84218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKK8"/>
    <dbReference type="STRING" id="6689.A0A3R7MKK8"/>
    <dbReference type="OrthoDB" id="285418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14514">
        <property type="entry name" value="DUSP14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052103">
        <property type="entry name" value="Dual_spec_Phospatases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45961">
        <property type="entry name" value="IP21249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45961:SF6">
        <property type="entry name" value="IP21249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="50"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="102"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT84218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="224" mass="24628" checksum="D0BE1383AD77E98B" modified="2019-04-10" version="1">MPEQIHNQVVVRIADDLEDKPIRVVSPSCRGKDQKKEPEQRKPRTGRAGEVSVILDWLCLSGARAVRQARLREFGITCVINCTVELPAVPLDGVEVASPNLSSYMSDIADKIEEERRRGGRVLVHCVAGVSRSPALVLAYLVKHCDMSLREAFLHARKARPNIRPNAGFFAQLIEFEREVRGGASVTLVRDAALGLAIPDVCEDELRALRDTREPCAAGTVGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQ27</accession>
    <name>A0A3R7MQ27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000761">
        <property type="protein sequence ID" value="ROT82893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQ27"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="467" mass="48931" checksum="35CB43586E6168AA" modified="2019-04-10" version="1">MSAFRSLSLGKVQSEPPPHITPSAHIFPITSGTPFPLLFPQGPLDPPLPSSLLSLSFSPSSSSLSIVLPLSLFLPLSSLSSLSPRLPSPAPLSLPQSPDLPLSPSLHPHCPYPPPPPPRPSVLPEPEASLIPHFHISPSPPLSLGTSPLLPLPPPPQSPSISLPLPPLLTLHTLPYSSPLLLLALLLPPPHSSPHTPPPYPPPSPPTPPLPPPSSSSTSSLSSNPSPAHLSAPSTSPLPSSPHSSPNPLFPHLSSYSPPSLSFTPSPYPPSPFHPNPTAFTPLPFPSPHPRTSPSTLSFSHRLPPLPFTPLTLPLSFTQPSPSPPLPILSPLLPQLPLSPLPLRPSLTPPLLHTSPYTPSLHRLSFTPLPHPHPSPSTPLPPPLHIPLPLPNPSSSPLSSYLLPLLPTSPPSLFPPLTPPLLHLPLLILLTLSPPPSPPSSPPPSPPAADPHASILIALGGFHTRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQJ1</accession>
    <name>A0A3R7MQJ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000708">
        <property type="protein sequence ID" value="ROT83266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQJ1"/>
    <dbReference type="OrthoDB" id="6378257at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018757098" evidence="2">
        <location>
            <begin position="16"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="164" mass="16130" checksum="2B7B493241516B2E" modified="2019-04-10" version="1">MKLLVISVLAVTAVAAPQGYSLTEPRGAGLSGDRGHAAVGDAFAGVRGGEIESSLITDISAGSKPSESEADAGFPLTAGLATESESSVGVVETAVSGGQRLGTNTASRAAIEDHSNVGESSSTEVDVSEDFHSGLFVSEAGRAASTGTSADNTGDSPSGLYGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MR94</accession>
    <name>A0A3R7MR94_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Crustacyanin-A1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023019</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MR94"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="5">
        <location>
            <begin position="53"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="16621" checksum="A6EFBD0D5CECB42D" modified="2019-04-10" version="1">MLASGTKLPSQTTHTNSSSNGSKFIAKSTGINADGNLMRHNGQVLPMPLGDPHLSIDYEGSFTAPYVILDTDYENFSCIYSCVEFNYGYYADFAFIFSRSPKLSDQYLRRCEAAFKEIGVDVSRFAKTVQGSNCPYDTRNLSKCLFDKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MTP4</accession>
    <name>A0A3R7MTP4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 9">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_008895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:19890"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 9"/>
    <dbReference type="EMBL" id="QCYY01000212">
        <property type="protein sequence ID" value="ROT85690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MTP4"/>
    <dbReference type="STRING" id="6689.A0A3R7MTP4"/>
    <dbReference type="OrthoDB" id="932129at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-alpha-D-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00897">
        <property type="entry name" value="UGPase_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000001">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000002">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000806">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>UTP</name>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000806-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT85690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="538" mass="60368" checksum="31FBBFACE0E79F3D" modified="2019-04-10" version="1">MVVETTTSSLPFVNGNLLTLNLANAARFATRGNVSLPRNYDRYSEVFGHQRSPSMEFKELTKKDAQVQLAHELQKLTNTCQAHLKETTQKDFEGFEKLFSRFINEVGPSVEWDNIQKLHDGAVRKYSELCGPDSSHARDMLNKLVVVKLNGGLGTSMGCQGPKSIIPVRSELTFLDLTVQQIEHLNKQYGCDVPLVLMNSFNTDEDTQKVIRKYQGFQVKTYTFNQSRYPRINKESLMPIAKTCSIESDLEAWYPPGHGDFYQSFKNSGLLQEFINQGKEYVFISNIDNLGATVDLNILNFLLGGDNSGHCEFLMEVTDKTRADVKGGTLIQIIRLRLPPKEHVDDFKSVKTFKIFNTNNLWIKIDAIDQILSEGTMDMEVIINNKTLDNGFNIIQLEQAVGAAIKCFNGSIGINVPRSRFLPVKKTDDLLLVMSNLYNLQYGTLAMSPLRMFDTTPLVKLGPNHFGKVKEFLKRFASIPDMLELDHLTVSGDVTFGKGVVLKGTVIIIANHGDRIDIPPGAILENKIVSGNLRILDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7M9</accession>
    <name>A0A3R7N7M9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sushi domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001867</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001249">
        <property type="protein sequence ID" value="ROT79419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7M9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57535">
        <property type="entry name" value="Complement control module/SCR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="Sushi" evidence="4">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="327"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="41677" checksum="66B8B77BB8DA075B" modified="2019-04-10" version="1">MSITNNETFRYHTFGLTYSCDYGYKGMRTVDLQANQRYTCTEITNSTYNGTHEGDFNYTYSYMPEDELLHCNRCAWSPAIPGATHTFSLNEVYVIGDTITATCLESHLLELDVTEQTVTCQNDGGITAVVSEVVCLETPSVVNATTTHQHDMWEVGEQVTATCNGDLYFADAQVQTRQVSCTNNGWVEAPGCETGSYIWVVEGIFPCVNCFISFGFIPCPLPCPLSSGPFLVHSPIHLPMFPLSCSPPVFPHSLCSSPISPSQCPCPPLLAPPSPLRALPLFTSSPNPPFPCALPYSPPLSSSSAPSPQLCTSPHFPSPCPSSPIHLLVPPSSVQGEAGCPGQNKRKLDGSEPRANEEGRGDRDGDLSARARTASRGRDRGPCSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N9Z9</accession>
    <name>A0A3R7N9Z9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000990">
        <property type="protein sequence ID" value="ROT81316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N9Z9"/>
    <dbReference type="OrthoDB" id="2668416at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052797">
        <property type="entry name" value="RegFact_GeneExpr_CellDeath"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33936:SF25">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33936">
        <property type="entry name" value="PROTEIN CBG17840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="322" mass="35971" checksum="198BDCD6232A06F5" modified="2019-04-10" version="1">MYTSGNIGFDVLVAWSSRSHHSGMKVEVNEIHFQSLSDFTEWKEEEEYRTHTFFSRASGKTHLKGAVYWYFTCQHDGSARFHCKKGEAGRLTNRKWMKGRVKTGLTCPSRIMARQFSDGRVSAKYISTHSHDVISENRKFQPLSGRLLSMVKQQLANGIAPKEIQKKLQKGIVLNNDGVPKKDHLVTLKQLNQLKRKIWQKSQPRLSDLCSLVSLVSKLKESPSDPVIVYKPRGQNIVCGNSSLADLPHSLDLVTIGLQTEEQQRVIKDNVLRILSPSSAVAEGGVSSPSITLVDSQSSTPSVSVVHPGDPSSSTAEYFQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NFN6</accession>
    <name>A0A3R7NFN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000150">
        <property type="protein sequence ID" value="ROT85932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1348" mass="150224" checksum="66F6498F3199B0DF" modified="2019-04-10" version="1">MIDLPLEDSIQVQISRFTSLASDLSFRSPAFTSLASSLASHLFTSLASHSRFTSLASHLSFIFASHLSLHNLSLHISRFTSLASHLSLQPSLHISRFTSLASHPPRFTASHLSLQLHITSRFTSLASHLSLHISRFTSLAYLSLHISRFTFSLHISRFTDLSHLSLHLSLHISLTSSLQTSRSSRFTSLASHLSLHISRFTSLASHLSHIASHLSLTSHASISRFTSLASHISRFTSLASHLSLHISRFTRFTFTSLAHITRFTSLASHLSLHISRFTSLASSRSTSLASHLSLHISRFTSLASHLSLTSLASISRSTSLASHLSLQHSLASHLSLHISRSSHLSLRISRIHLSLQHISRLHISRFTSLASHLSLQHRSRFTSLASQSLASHLSLHISRSHLSLRISRSHLRFTSLASHLSLQHLSLHFSRFTSLASHLSLHISRSTSLAPHLSLQISRFTSLASHLSLHHSLHISRFTHLSLHTLASHLSASHHSLHSSLQISRFTSLAFTSLASQSLAFTSLASHSRFRSLASHLSLTSLTSISRSHFSLRFTSLASHSLAFTSLTSHLSLHISRFTSLSHSLHFSRFTSLAHISRISRFTSLASTLSLQISRFTSLASHHSLHISRFTSLASHHSLHISRFRSLASHLAFHLSLHISRFTSLTSLASHHSLHFSRFTSRSTTSLTSHLSLSSLASHLSLHISRFTSLASTSLASHLSLHISRFTSLASHLSLHISRFTFSLQHLSLHISLSLASHLSLHISRFTSLASHLSLHISRFTSLASHLFASHLSLHISRFTSHHISRFTSLASHLSLHISRFSLFTSLASHISRFTSLRSLTSLASHLSLQHLSLHISRFTLSLHISRFTSLASHLSLSDLSLHISRFISRFTSLASHLSLHIISRFISRFTSLAFTFSSIISRFTSLASHLSLHISRFTSLASHLSLRLHLSLHISRFTSLAFTSLASHLSLRISRFTSLASHLSLSHLSLHISRSRFTSLASHLSLHISRFGSLASHLSLHISRFTSLASHLSLHISRFISRFTSLASHLSLHNLFALHISRFTSLASHLSLTSLASHLSLHISRFTSLAISRFGFLSRFTFLASHLSLQISRFTSLASHLFAFRSLASHLSLTSLQLQISRFTSLASHLSLHLSFPPASLFSLHISRFTSLASDLSFLSLHSRSRFTSLLRISRFVSLHFSLHISRFISRFTSRFTSLASHLSLHIFSLHISRFTSLASHLSLHISRFTSLASHLSLHISLHISRFTSLASHLSLHISRFTSLSSHLSLHISRFTSLASRLSLQISRFTLHFTSLASDLSLQILRCPHEAQHRRRQMNTPDIKIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NTQ3</accession>
    <name>A0A3R7NTQ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002932">
        <property type="protein sequence ID" value="ROT66455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NTQ3"/>
    <dbReference type="STRING" id="6689.A0A3R7NTQ3"/>
    <dbReference type="OrthoDB" id="10065127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="121"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="202"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="715"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="687"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="971"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="609"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="796"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="923"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="971"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1070" mass="112448" checksum="91A208A31929CBCB" modified="2019-04-10" version="1">MAAQLSDGRVRLNSASPSPADRPLSHSALYCEIHDYKFRCLMGTVFDQETRVCERADDVDCSRSESFFHLNNELYGPGIIPSTANIRISDTIDDDPTAVFGPVNAAPSTTTQPPFVFPETTFSCHDKIPGGLYADVETGCVVFHICSVEPDSSTKDNKFVCGAGTLFDQTTRTCQAEHLVDCARAPSLYYLNDPLRGPADAVDLCRTRPLGSPLADLTSQCHNYTVCEERGDGGVAERRLPCKKGFLFSQLRRRCVPEKGERVNCAKETLGEILGLGGARQSPSGSSRRRRATSLLLSHRFRRAALTPLANLVPTHGVEDARVRRALYSLAALQQWAQENARHTAFINVYTLNTRGKDGLFPKKAFGDGGAAPPTAARRGADRWAGPGRPRRPGGRPRGAPAGPGGDRPRRHRSRPKDDRGAAHVGPRVRGPPRLEHQTATVITNQSSGSPASTAAPSLIAETSPLPTVSLSPTVASVVNSAVTESLSIDSSSPSETKPEAVTPVTEASSSTPGVPQEAIVSSTVGTTTASSSTESSAVETPVNSNAENTTVTTTTEATTTTEVTTAAVSSAPQAVGNSTTESTPVASSTEPTVAEPAINSTEVKALDSSPETSTTTTTTSPAANASTSGTTASPAPASSSPDAAAPASEDASAANATATTSQPPDFTVPEGSINVSTTVVPGEADALGNGTLVQPTPAPPTLGTFTRDNLPETSFTCKDKQLEQFYPDPEANCQVFHYCSPGFVKQQVLDLKFLCTGATMFDINTQKCEDMANVTCSFNDTVTTPPPPTEPPTTPSEEPTTTTVITSSLTTTVTTPTTTANTTVAPSTTTEAVPTTVAAAGDTTETTTTTTEASTTTTEASTSTTEAPHEVHHNWNATKPDVKANESLVEEKAAEIELFETTTVETEVREVTEVDLPETETVTDRAAREEVSTSTEGFEEAFETTTEYFLVEEPEINTELGPIVLAPDSAEQQPVESPTNPEISETSEAPETSSSTTTPVPEPTTDASTQESISPQTPAPTETVPLTEEAPSASEELESSVVSIARNASESTHTASTSSTEATLAEAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NYZ9</accession>
    <name>A0A3R7NYZ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002388">
        <property type="protein sequence ID" value="ROT70759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NYZ9"/>
    <dbReference type="OrthoDB" id="2386367at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046">
        <property type="entry name" value="G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32046:SF11">
        <property type="entry name" value="IMMUNE-ASSOCIATED NUCLEOTIDE-BINDING PROTEIN 10-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="439"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="54744" checksum="C65AE04D5178D05A" modified="2019-04-10" version="1">MEGGLRGWVERNSVPVRRESGFTVRELRTRTVLDDPTNKVRVLGVGPENGGEVKKVLLLGETGQLCKNALVNRVFGVGLRDDVRLQLRDQMDEAGKSSTQSQTEYTTAYVIYRQEGMPRGHNLMVIDTAGVGDTGGRLREESNERQFRRCLAEHAWVRELSSVGLVWKASDHRYDQRKKDVLGRLKGLLGYDAKPITDILVTFSTNGSRDAFDIMREAGVGFHGEFLFDNGPLYKGWPQDAMRRRKLEMEWEMMEESLDGFLEAVSERRAVELTATVGLIRSQFELEDTNAELQALWEQEDELRQTIREHERKLCRLDGKENEVDWDEVRALDSSREELVLENGQHCHYCPECDKVCVPSCSKDPDGERITEVVTGVISIGIFGITRALGLPQPLSCSECDHLPVIHHFNRTILVKHATRSQKVELAKKSQYKRVMQQKADIRADIGAYNAQLKEVEKQHARTTTKFKELEHRISHLKSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6D9</accession>
    <name>A0A3R7P6D9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019772</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003703">
        <property type="protein sequence ID" value="ROT62380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6D9"/>
    <dbReference type="STRING" id="6689.A0A3R7P6D9"/>
    <dbReference type="OrthoDB" id="5953636at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016768">
        <property type="term" value="F:spermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000197">
        <property type="entry name" value="spermine synthase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015576">
        <property type="entry name" value="Spermine_synthase_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315:SF1">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="126"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT62380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="369" mass="41495" checksum="C2E18ECD46D4AE9A" modified="2019-04-10" version="1">MAGHSVPVDFRVNPAKISNPVERKTLLQDMLPLIEPFTGSLTEISVCEVPGGNFVALYASDTMTLSVKLYSNGLVTATVEYYTDQVNEHKIANDHGRALEKQLMAKFDCSVAKVLPAIKRAPPVNPYFTSSDDRLLEYDTDGIVFEEQSEFQKVQIYSTKSFGNLLVLDDLQNLAEQDLPYTHGLMNKDKEDFAGKEILILGGGDGALLWELLKEKPKFVTMIDIDDVVMKACRKHMKSVCGTCMDNYDGENYKIIVGDAIKYMKDYIKEGKQFDYVFGDLTDVPISPTPRGQLWDFLRTILGLGIQCVRPGTGKYMTHAIGIQCSSALKMFEEQFEAQDIPVTLTRTSHYVPSFMEYWCFYQATRKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7R8</accession>
    <name>A0A3R7P7R8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RETREG1-3/ARL6IP-like N-terminal reticulon-homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_003429</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RETREG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001463">
        <property type="protein sequence ID" value="ROT77872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7R8"/>
    <dbReference type="STRING" id="6689.A0A3R7P7R8"/>
    <dbReference type="OrthoDB" id="10029527at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057282">
        <property type="entry name" value="RETREG1-3-like_RHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043384">
        <property type="entry name" value="RETREG1/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28659">
        <property type="entry name" value="RETICULON-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28659:SF2">
        <property type="entry name" value="RETICULON-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24456">
        <property type="entry name" value="RHD_RETREG1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="RETREG1-3/ARL6IP-like N-terminal reticulon-homology" evidence="11">
        <location>
            <begin position="40"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="273"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="452"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="452"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT77872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="504" mass="55930" checksum="A172CED430904833" modified="2019-04-10" version="1">MASWRNALLRLWPFRSENTDSSSSQWGRKTETRKIARALGPWEAYMVTVQSILIWESPGTSALAVVGVNVLFWLVVWSELRVYFVASVAALAVFLHQQWVHTIWPEIRVPKPEPDDTEDWTPVHPSVLSVPEISQYVEGAWRCICDNYTWLLHLRRVQPALFCAIVSTVLSVGAVVGHLVPGAVLVYILLMLVMTGPGILLHVLPDSFYERLAKMRAALRGEDSEMEISNVSLDSDLTEFMPELQSAEAQAALDVPLMSQDPPEVEQMVEDAYLQEESERSTRKRTKNTGGGERSEGAPAAQGLTLPLSTEDGISSTFFTSGLPEDFPSYDHDSVEDLDGPDIELPDLPKVVREPVPERQGAGGDRYQMEFVSSHFGDSSEEEDAFLEGLTFEERVQARPEPRAQPHIPSQTNTSPPMDPIGQLMTSVIAQNAGNVLSALGQNLMTSVIGQAAAQAQPSPQMSQQPRRTAAEPTARMTRSQDRQQQSVTDLEEDFELISDEEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P879</accession>
    <name>A0A3R7P879_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">nitric-oxide synthase (NADPH)</fullName>
            <ecNumber evidence="5">1.14.13.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_018480</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NOS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.39" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01003406">
        <property type="protein sequence ID" value="ROT63633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P879"/>
    <dbReference type="STRING" id="6689.A0A3R7P879"/>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004517">
        <property type="term" value="F:nitric-oxide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006809">
        <property type="term" value="P:nitric oxide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000002">
        <property type="entry name" value="Nitric oxide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000033">
        <property type="entry name" value="Nitric oxide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.340.10">
        <property type="entry name" value="Nitric Oxide Synthase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1230.10">
        <property type="entry name" value="Nitric Oxide Synthase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050607">
        <property type="entry name" value="NOS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044943">
        <property type="entry name" value="NOS_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044944">
        <property type="entry name" value="NOS_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004030">
        <property type="entry name" value="NOS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036119">
        <property type="entry name" value="NOS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43410:SF1">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43410">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE OXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02898">
        <property type="entry name" value="NO_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56512">
        <property type="entry name" value="Nitric oxide (NO) synthase oxygenase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="10" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="15">
        <location>
            <begin position="233"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="16">
        <location>
            <begin position="477"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT63633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="724" mass="80840" checksum="C97E1FEF8AE3BA97" modified="2019-04-10" version="1">MEAERRAVDVLPLVLSANGHDPEYKWFTDLDLQWYALPAVASLMFDCGGLEFPAAPFNGWYMVSEIGTRDLCDPHRFNILETVGRQMGLDTRSPTNLWKDKALVEVNIAVLHSFQSLNVTIVDHHSAAESFMKHFENEQRLRGGCPADWVWIVPPLSGSITPVFHQEMSLYYLKPSYEYQDPAWKTHVWKKTKDVNRNSVRKTKRKFRFKEIARAVKFTSKLFGKALSKRIKATILYATETGKSEMYAKKLGEIFGHTFNAQVCCMADYDLINIEHEALVLVVTSTFGNGDPPENGEEFAKNLYAMKVSGTAADIDDVTSRMNSLTEGAGAPSTPLENGLASCNLRGSITSDIMSEDNFGPLSNVRFAVFALGSSAYPNFCAFGKYVDNLLSELGGERLMKLTCGDELAGQEQAFKQWAGDVFTVGCETFCLDDDVAMKEATAALKIEATATANKIKLAPCTKTDAIDIGLSRMHGKRVRSCQVLGSRNLHGENASRWTQQVIIDTGGINELNYSPGDHVAILPANRKELIDAVLARLDNCPNPDEPIQVQVQKEVHSLNGVIQTWEPHERLPSTTVRELLTRYLDITTPPTPNFLHLLAEYAYDNDQRTRLDQLATDPHEYEEWKHLRYPHLKEVLEEFPSVVLDAGLLLTHLPIMGPRFYSISSSPDAHPGQIHITVAVVIYNTEMHPVSTCHVTQVSPLFLLDLGQELRHLGAFGTIVFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNA7</accession>
    <name>A0A3R7PNA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002222">
        <property type="protein sequence ID" value="ROT71962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNA7"/>
    <dbReference type="OrthoDB" id="425925at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="654"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="578"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="766" mass="90265" checksum="8804F2D42AC2FD10" modified="2019-04-10" version="1">MNPDTISKGVHRLADLLRDSSWQRDTLERHVSGVTQELREKRRMLEEAESARAELERECEDLRDQLEEVQKGERPTPEGGPRAGGGGLPTIEEEEDAEGEGEGAEREVKEARRSPTGLGGEDEEEGEVAKMGMEEGGKDGKVRKRDGRDAKKEQAEDEEESSRLSRIHYLEAQVEALSEARRNLEIEVVRLRAEQGDALARLRDREEGRAGNILNLETEAASLRQVKVVLEEEVGTLKAEEGHAIREEKERLMGQLDTLTRQLDLEAVTHKDEREGLEEKQHALEEKIRTLEDELGHLRASEGLNAHERQSLGQQLLLQYRAVEERNELISRLEGELHDMTLKQAVLQAPERTLEDLRMQLEEREKELNAAKSQIIFKDDKVDELNQSLSELRGKITELTKSLSERDEKLRELSKEIQKRDEKVSELTQNLSENNDKVNEMTLEKMTEVSALKEQVEREREEIERKREEVERKEEELERKNGEMEQKKEEIERDREELKINKEELERNRDQLDHSETELFQLREKMEELINENKRREEEQKEKREEEEKKKTEERETWNKEKEALERVKENLVQEIEKAKLRESEREKQDDSTIKQRREEEEREEEERNRMKQQIECFRGEREEMIKALKQKHEESLAYHAEVQRLSAVLMQKARREEEKARREEERAKREQGEWEKGQKAITEERDQLRLANAQFNNQYQEQSKELAQLRERETRLASECERLRQHLINVEEAYTQEIVKGEERETTLKKALSKMEERMATVAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNU9</accession>
    <name>A0A3R7PNU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative neurotrimin-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002146">
        <property type="protein sequence ID" value="ROT72486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNU9"/>
    <dbReference type="OrthoDB" id="190835at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032589">
        <property type="term" value="C:neuron projection membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000129">
        <property type="entry name" value="CLUMA_CG018772, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037448">
        <property type="entry name" value="Zig-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279:SF36">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE 9, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23279">
        <property type="entry name" value="DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="57"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="1">
        <location>
            <begin position="160"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="201" mass="22448" checksum="B8F61D1127C145D2" modified="2019-04-10" version="1" fragment="single">MNNYCALFFFLPHPPVLNHFVSPSSSFVDGGTEAEILKALDEAAAEGAWGYVPLSGPYIDPQHSGNVTAQVGATAVLNCRILYIVGKTVSWMRTRDLHLLTVGRFTYTSDQRFKAVHQSGSQDWLLKIHYVQHRDAGPYECQVSTTEPLTHTVWLSVVEPQTTVFGGPDLYIDAGSVINLTCLVKYSPEPPPYIFWYHDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRA1</accession>
    <name>A0A3R7PRA1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001877">
        <property type="protein sequence ID" value="ROT74585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRA1"/>
    <dbReference type="STRING" id="6689.A0A3R7PRA1"/>
    <dbReference type="OrthoDB" id="272161at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050694">
        <property type="entry name" value="LRRC14/PRAME"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14224:SF37">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14224">
        <property type="entry name" value="SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="75392" checksum="47AFAE6C6F3854CE" modified="2019-04-10" version="1">MLEGSFYHLLESLLPPTKSPTDHLKLRKDGRRFSIVHGQDLLRLEYLSACKVMQDRETTARLLPAVPHKLYPALFEAAILHSFYSRKGPGWKQTTLSSSVIPLILHWPYETMCVRDLIPPLPPPLRKCRGDTLNSVGQRLQHFYDNVMHLIPHTFLQGCTDTEGERNLRALKTLDVSGHYTQVDGILSPTHLLQMVKKAYNPNTCTEYERFTIVVDVRIDDGSEKKFNDLGIICTLSQHHGAILVVKLRSVHIVSVSMKKIQYFIELLANNGTECLELEMCDVDDSGLDSLLCMSECLTSLSLAYNRSITSLHFLAGMSNLCQINLSGIRLRDKVEALSALPRGLEYLKMVGCFLKSPDLEALSTTKHMLTLRQLDLSENSFGLPADFFALCNLCKNLVKISVLELEGCFLNVVLPESLTQLVNILSSLPDLCYLRLTRNDFSSRVIRSHLSDLAHCKSLQYLCLTTPSDMYISALLRPHPKSLSSPSPVSPNHTPPPSSLLLPREITLLARPHSPSLLILSLLEFLLDGPPLHSSFSLCFSSPPSLTASRSLSPSPCSYLYLPSYCLPPLLIPTSLQPLFLLTIFYSYCPCIPCLLLPGPRLLLHRTTSPPDSSFDLIRSSPPSLPDAPPSTPLFAHRSSKSDSTDTLVWAPSLTLLSVQHPHEFSSVSHKLHIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRA7</accession>
    <name>A0A3R7PRA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001146">
        <property type="protein sequence ID" value="ROT80172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRA7"/>
    <dbReference type="OrthoDB" id="6370747at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="238" mass="27012" checksum="AA47FFC5FB4E160B" modified="2019-04-10" version="1">MPVEPLENDCFLLISDDFELVIEEEEDGWCHVVPNASAAFEATPPEDLPLASASSSSPPPPKTDLSPSRRKNEDLFFLDGHYETAVPDDNEGAKAGAADVRVVEDVDIQEVEVEEEADAASEVEEDYEEFWEADELVDAYCLNYGHDDVIDKAAEDFGAKRKIGLKGSRQRKKEAAKRPVGKDLYMNQDHLNWREFKKQVNKTFQKQHLDWPTYKRNLKKSPFGCALSDKKKNMLIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PS97</accession>
    <name>A0A3R7PS97_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006072</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001777">
        <property type="protein sequence ID" value="ROT75396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PS97"/>
    <dbReference type="STRING" id="6689.A0A3R7PS97"/>
    <dbReference type="OrthoDB" id="6021076at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="6">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="12645" checksum="FFA6111A0E377982" modified="2019-04-10" version="1">MFMFIVSLPYAVLHGGYWALVAMIGIAYICCYTGKILVDCLYDLDENGQLVRVRYSYKGIAKEVFGQKWGGKIVNTAQLIELLMTLHPVRGPLRRPDDRQLPRRAIDARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PU16</accession>
    <name>A0A3R7PU16_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004331</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001573">
        <property type="protein sequence ID" value="ROT77043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PU16"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="425" mass="47466" checksum="5524A49F9EBE8106" modified="2019-04-10" version="1">MHELCTNTHLLPPYLPTSLPLSHSLSLPPSLRIYPPTTYLPTYPPPDLPTYPPTYLPAYPPTYLPAYPPTYLPVSTHHLPAHLPAYLPTHQPINQPTYLSTYPPTQLHIHPPAHTLYHPVTQQPSYLPTHLPIHPFTHLPTHPSNNLPTHSPNKLPIHPSNLLPTQPPTHSTSYPLNLLPLTTQHLPTHPPNHLPTHPPNHLPTHPPNHLPTHPPNHLPTHPPNHLPTHPPNHLPTHPPTTYPLTHPTTYPLTQPPTHSPTQPPTHSPTQPPTHSPTQPPTHSPTQPPTHSPTHPPTTTYPLTHPTTYPVTRPTTYPLTHPTTYPLTHPTPTHSPIQPPTHSPPTTYPLTHPTTYPLTHPASYPLTHPITNSLTHPTTYPLTHPTTYPVTHLTTYPLTHPTSYPPPTCPPTHQHTHHRQHIHLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWC1</accession>
    <name>A0A3R7PWC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NOC3-like protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleolar complex-associated protein 3-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_022066</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000505">
        <property type="protein sequence ID" value="ROT84721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWC1"/>
    <dbReference type="STRING" id="6689.A0A3R7PWC1"/>
    <dbReference type="OrthoDB" id="10263597at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="9">
        <location>
            <begin position="193"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="8">
        <location>
            <begin position="531"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="863" mass="99482" checksum="E776B4AAC3C81302" modified="2019-04-10" version="1">MAKPGKVGKGGTSSKMGKRKDKKEGGRMSKKVHPEKLKNIMKAKEAKKNSRRMTNRSEKKKEKRGLLRQKEAQRAYQAKIDEDVEYQKKLQIELAGGNDPRSNHQVKVMDKRELQALVQSQKRVLLDEMEDELAKEDVRVGRTAAVEPDPLSQYKSVEDEPRSFEKNPIPSWVRTMLPIKNQQGGIVARYLAVDAIIGEPEEKIKLLKNLEAYLKEEDPDIAITVRKYAALSMFEVFNHLIPTFELGEETKDHKSLLRKEKKQAYKFEDDLLFEYKQYLITLEANLKDKKLQNEHSKEAFNQLMIAILKCYGELLLRKGHFNYTFNIVQVITPYGSYKVKEVAQVVLDTFKKLFIRDKTGEMTLEIVMQMDKYIRRKFFKVEPYYIQAFLDINISNVKNLDALIEAHRNASKKLTHTQKLIKKVIEERAPKKSIKERKKCKKQRILEEKMREFKDIRSNRKRQEAHSKILQIVFGIYIHVLKRKPNKVLNEVVLEGLAKFAHLINIEFFGDLLDVLGQKMLEGTMNFRESMFCIKTVFTILSGQGEALTLDPRQFFTYLYANMLKMGQDGNQSNVFPTLDALKMMLVHRQRCVNSERSLAFAKRLATLSLAQPFHNNVIASLSVLRGIVLNNPNTKFLLDSDTEGTSGIFQPEVKEPEHCNAGATAFFEYRLLSRHYHNFVQKMTHHLVNSAPLHGEGSLPIDMTRKTLQELQDMFDPQEMCFNPTVPKPELHLPKKDERKMTSKKNRRARFITPYMQKQMEELVTDENRNRLLGHEASGMGHPNGHAANGISGVNGTKKQDEENGMDADTSEEAMISDADFFKGMIWNMDLASIPSRQNTNGEPEGRWDKDVTLELVKVEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWN3</accession>
    <name>A0A3R7PWN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001245">
        <property type="protein sequence ID" value="ROT79439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWN3"/>
    <dbReference type="STRING" id="6689.A0A3R7PWN3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="969"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="846"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="882"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="854"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="910"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="933"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1036" mass="105220" checksum="92A02DCFE6FF05AE" modified="2019-04-10" version="1">MAALQVILPRAQIRPPLLSWRGAQIVLGLPFLLGGAQVHLILHSILLAAAQVTSFSSSLADATDRPASSSWRSSRSSPPPPPPGGRSKVLLILPPGGASGLLLLFLAELRSLLLSSPGGAQVSLLSPRLLAAVLKDPALLLASWRFAQGPWPAFPGGTTQGLLPSVQVLVLLPLPGGAQGSHLPRLSLSGALADPPSARSCLWRRLRFSPPSSSWLADQAGRLQVVIASSSSTGGANRVSATPPLLLGRRVQVLLTPPDWGAQILLLLPPGGASDPRSDSSPGGGRADTINSYPGGAQVCSSSRSGTSGARLRSTPRYLLLPGGRLAGCILLFSWRAIDRLLGPPGGARAEPHMGYAQVWRASRLIQSSSLDLARTCAAPRSYGSYTTGLAASILTADSTPPSGQASESPPSSPGRLGAQIARSSLHSLSSSSWRAAAGPPALLTPSLAAAYKVACGCRTSWPPSSWTGVWSALNGGALPSGSFLQLAAPKGLPPPLAGAHQGSQSTPLASSPCGRRCRLPDTIPRASTSLGGAADPRLLLSLGGAQAVSSSILAALRSHTTSLPSSCSAALQQFLRLAKPLAASRSSHLTCRYLARRSDACFLLPPGVLMRSTATASSFLAASGLPPLLLASLRCLLSSSRGGGQVSSSPRRRSGPPPPRLAARSGAPSSSPPWRVSSILLLLAARRSDPPPPSWRRSGLLLLLRRLGPPPPPLAALRFLPLLLAALRSPSSSSSWRRSGPPPPPPPGGAQVLLLLLAAAQVLLLLLAPGAQSSSSSSWRRSGLLSSSSSALRSPPPPPGGAQVLPLLLARSGSPSSPPGGAQSSPPPPGGAQVLLLLLLGGSAAAPSPPPWRRSGSSSSPPPGGAQVLLLLLLAALRSSSSSSWRRSGPPPPPPPGGAQVPPPPPPSGGAQSSSSAALRSSSSSSWRRSDPPPPPPPSSSSSLPPPPPPLPPPPRSSSLSSSGGTQVLLLLFLLLPLLLLLAAIRSSSSISSSCSFSSLSSSSSSSSSSSFSSSFSSCLGTLASGNGNSFAILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWT2</accession>
    <name>A0A3R7PWT2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001724</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001225">
        <property type="protein sequence ID" value="ROT79562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWT2"/>
    <dbReference type="STRING" id="6689.A0A3R7PWT2"/>
    <dbReference type="OrthoDB" id="10540276at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="642" mass="67698" checksum="939A1411E5CE0F91" modified="2019-04-10" version="1">MLLQQQKPQLMLLQQQKPQLMLHAPTAEARCCRSHNDAPTTATTDAPTTAEATTDAPTTAEATTDAPTAEATTDAPTTAEATTDALMLLQQQKPQLMLLQQQKPQPMLLQQQKPQLMLLQQQKPQLMLLQQKPQPMLLQQQPQPMLLDAPTTAEATSFLQQFLQQSHNPCSYNTEATTDASITAEATTPAPTTVKATTDAATTAEATTAAPATAEATTATPTTAETTTDAPTTAEARTPAPTTAEARTADPTTVEATTDAPITAEATTPAPTTEATTDAASTAEATTDAPSTAEATTTAATTTEGATDGPTTPEETISVQGTSALISTLVPTTYASTELSLPTTTPAPKTPLTTKIVLTTSEATTSATTSATESPLTTTVPTTDPPTRDSPLATTTPDTATPTSAPTTEPPATTSLADLLNALDQYNDELANITSDNSTDMLDAALEALYDLLEVLNSSSTTTRFVLRNIEIEGCQENSTVIKGKVFDVVKQIVDELRDTVLQDPGRANAEIIQCLEEKIYELAGNMRRLKLSEQEKAILKCHVTNAINVLQDYRDGVPSSDYEIQEYQDLSSPLSSLFSYLHLFLSSLDSLSFSLLLSLSLSFTSPPPSSALPSPSDEALALPAGRPSGEHDGSGVAVEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWY4</accession>
    <name>A0A3R7PWY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001200">
        <property type="protein sequence ID" value="ROT79715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWY4"/>
    <dbReference type="OrthoDB" id="6375917at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="184" mass="20014" checksum="DC9AD62AA516B833" modified="2019-04-10" version="1">MEACWLVGIPELNTASMEYPTKEKLQLDAHPLPSAPSAANPREENTCCCGCSWRTGAITIAILYLLANLSIGGFLIVLLSMDDDRVPTLIAIVTTGIAIIFILLLLRGAVKRRPPFLLAWMCWEGLNIGLSAVVVAITLFTLGMSACIGALAFAIRCWCFFVVFTYRKTLIAQPPKREANNAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q089</accession>
    <name>A0A3R7Q089_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aquaporin-3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aquaglyceroporin-3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_016823</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Aquaglyceroporin that may modulate the water content and osmolytes during anhydrobiosis.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair. In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer; each monomer provides an independent glycerol/water pore. Could also exist in other oligomeric states.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003118">
        <property type="protein sequence ID" value="ROT65223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q089"/>
    <dbReference type="STRING" id="6689.A0A3R7Q089"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023275">
        <property type="entry name" value="Aquaporin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02015">
        <property type="entry name" value="AQUAPORIN3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT65223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="305" mass="32285" checksum="5F9ACD8C3E8FA926" modified="2019-04-10" version="1">MNESQAGTRHSAQSSCSRASRCLIFGDASVAQKVLTKDANVTSLGQLGWGVAVTLGVLVSGGVSGGHINPAVTVAMAVWGKHPWVKVPVYVIAQYLGAFMASSMVYAVYLNALDAFEPERSLATAGIFATYPGAMTASNGTLVTDFLSNGNGMGDQVVGTMLLLICVCAITDPRNMEVPKALIPLFVGFTVLNIGVCFGFNCGYAINPARDLAPRFFTLIAGWGEQTFTAGTFDGIAWWWVPLVGPHIGAVMGVGIYLLLIELHHPEAQEFSLPHVHPSQDTVASLGTEGKYSSKNKIMVSLILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q192</accession>
    <name>A0A3R7Q192_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TGF-beta-1-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000697">
        <property type="protein sequence ID" value="ROT83359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q192"/>
    <dbReference type="STRING" id="6689.A0A3R7Q192"/>
    <dbReference type="OrthoDB" id="6359008at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF146">
        <property type="entry name" value="CD109 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018702244" evidence="1">
        <location>
            <begin position="25"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-2-macroglobulin bait region" evidence="2">
        <location>
            <begin position="562"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="723" mass="82275" checksum="7586BD0AD9145CDA" modified="2019-04-10" version="1">MALCRGGGTSCFLLLLLCLIPALAQNLGRPEDDPRGIKYGSDNRWRNVLQLNSPRMRNRYNHPTHMILAPRTLRPGAVYRCVVSILYLDHPVDVRASLQKDGVEIASAKQDIIKGYPETLLLQVPRTSVDGHYRLRVEGNIPGTIGGTIFFNDTRLHFSTRFLTILVQTNRPVYTGDQVVRFRIILLNTELKPYDDPVDVYILDPDNYVMRRWPSRPTNVGVVSMEFTLPFLPKVGYWGIKVLVNGQEEIKRIKVEKWYTPRFEVKIFMPKYFLDTDEAIEGVLGGEFGNDKGAYGNATLKLFVKNKINPNWTYVTEQIFEPFEGEMDFSFPMEDLSKRISNLDGSEIRLEAEIQETFMMLNETGFSMAKIINSSVNCRFLGSPPYVFKPGMPFEATVAVSYHDLEPLGEEKLHGSKLVVKAEAVLESGSRQVVYDIEIPQVNSEDEEREFLDQSWKYNRKAQDYQAEGYKLDDYDYNFNFDYETGSRYLTENELVQKKMEMFVRNQKFQKYREKGVYHFVVDVPEKTAALSLTASYQDDTGSIAAANAKAIAYYSPRKLYIGVETSSREASVGEFVVFHVRSNFNMESFHYLIMAKEMILYAAKEVLERTSRASVKTVSVPVSSEMAPAFKIVVYTTTPNHDIISDSLTMPVDGISRHKVKLVINQDKDHSKRTVELGTYSTAGAFYGISGVREFTYAMRGGNELSHASVLNSLHAFANNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q446</accession>
    <name>A0A3R7Q446_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cullin 4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_013829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002723">
        <property type="protein sequence ID" value="ROT68050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q446"/>
    <dbReference type="STRING" id="6689.A0A3R7Q446"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1310.10:FF:000003">
        <property type="entry name" value="Cullin 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.130:FF:000001">
        <property type="entry name" value="Cullin 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000050">
        <property type="entry name" value="Cullin 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016157">
        <property type="entry name" value="Cullin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01256">
        <property type="entry name" value="CULLIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Cullin family profile" evidence="5">
        <location>
            <begin position="148"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT68050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="57798" checksum="1C1AAF32671531AB" modified="2019-04-10" version="1">MPAFPHTHPPPLPPPSPSILLLLQLIRPQVNNHTLLEFTQSDEDVGSLRVTEAMLWVYVRRLPGARHHDPSESKTTLWVFRIPPEDTRESFGKTIVINPEKDKGMVQELLDFKDKMDGIVSECFSSSDKFVLALKEAFEHFINQRLNKPAELIAKFVDGKLRAGNKEATEDELERLLDKIMVLFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKQECGPGFTSKLEGMFKDMELSKDIMLAFKQNSHLGGTSMELNVNILTMGYWPNYPVMEVNLPSEMVKYQQIFTKFYLAKHSNRKLQWQPTLGHCVLKAAFPLGSKELQVSLFQALVLLLFNDADSLSLADISSGTNIEDGELRRTLQSLACGKARVLQKMPRSKDVNDDDKFFYNKDFTNQLFRIRINQIQMKETSEEQQQTEERVFQDRQYQIDAAIVRIMKMRKVLPHNLLITELYNQLKFPVKPADLKKRIESLIDRDYMERDKDNPNTYNYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4Q1</accession>
    <name>A0A3R7Q4Q1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">STE20-related kinase adapter protein alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002659">
        <property type="protein sequence ID" value="ROT68513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43907:SF1">
        <property type="entry name" value="GH18 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43907">
        <property type="entry name" value="SLEI FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="763"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="893"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1271"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1354"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1480"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1839"/>
            <end position="1931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1978"/>
            <end position="2029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2080"/>
            <end position="2108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2131"/>
            <end position="2223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
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            <taxon>Metazoa</taxon>
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                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
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            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
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            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
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                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
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            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0004879">
        <property type="term" value="F:nuclear receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.565.10">
        <property type="entry name" value="Retinoid X Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035500">
        <property type="entry name" value="NHR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050234">
        <property type="entry name" value="Nuclear_hormone_rcpt_NR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001628">
        <property type="entry name" value="Znf_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24082">
        <property type="entry name" value="NUCLEAR HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24082:SF482">
        <property type="entry name" value="NUCLEAR RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00105">
        <property type="entry name" value="zf-C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00047">
        <property type="entry name" value="STROIDFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00399">
        <property type="entry name" value="ZnF_C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00031">
        <property type="entry name" value="NUCLEAR_REC_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51030">
        <property type="entry name" value="NUCLEAR_REC_DBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nuclear receptor" evidence="10">
        <location>
            <begin position="309"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="250"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT80563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="543" mass="60577" checksum="68CCCC034884CF4C" modified="2019-04-10" version="1" fragment="single">MTGDYTPGWDTTRVLATWSKRARDVNYSSQRSEFAKQPSVKRILKQANFDHYLTPSATHPVTGRVALLTLSFLAHALGDTAHEVSTVRPPGVPCTHLLLVAVWYMMSKDAYYQYRAEDTGSVDGLGLPSLPNTSYWYDAHSSMGSSLYPVTSAQDYVIQNNESQLPISESYREPMDWWAENDVSAPRNLTGNLCSIGGVDQGYLSTDDLMCGPSEFEPAGPAMGMLGNGFVGPAPGPGGEREYVSPMEDMATDESLTPSPQSLPEDSAFASPARKGAASDTRRPSPVQEQSAKEQKKQKKEPKEKVKESKKCGVCGDTARSMHFGGMACDSCKAFFRRSVQSGAYKSFQCPENENCPISKQNRKVCQYCRFKKSQENGMEISWVMSETDRMVLWKNRLAKQRQEQEDKLKDVAYGGLPHTLDPDDADTLRNLAALQEATFKSIPYPEDCYGDNVETLANLFVCICKKLGLFFYRVEDFQYLCKTDQSLLLKNGIGMGIYLHGAYMFDHENERWPAEGNKEALMIPPVSLDTLRKFTVFPEAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QL55</accession>
    <name>A0A3R7QL55_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002370">
        <property type="protein sequence ID" value="ROT70917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QL55"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="41050" checksum="C998E6FC42607431" modified="2019-04-10" version="1">MVPPLWHSPPHPLQHPLALSPFLALFPHPLALSPPPWHSPHPWHSPSHLALSPPPWHSPHPFGTPPIPWHSPPPLGTLPHPLAPPPPPWHSPPLAGTLPLLPTTYREALPWIAFSAVSLSPRTPPHSLYSLSLSSLLTLFSASLSDSPLTLSLASPFRSLHSLYSLSLNSPLSLSLHLRLNCPSVSPSSLCRLLHPLPFPLSLFSLKLTLLKPLLSPLNTLFSFFPSPQSLPQPTLPLSPTIPKPPLNPLSLSYFPSAFSSTHSPLRPLPQPQPLPPHLPPLSPKPFPSTHSSSQSFLLSPQPLPQSHSPLSPLSPKPFPSPTLPQAYSPLSLSLNPLSTQPLPQPTLPSTHSPSAHSLSLLKHSPSHSPLSLFLKPTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRC5</accession>
    <name>A0A3R7QRC5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative signal recognition particle receptor subunit alpha-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001784">
        <property type="protein sequence ID" value="ROT75351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRC5"/>
    <dbReference type="STRING" id="6689.A0A3R7QRC5"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17876">
        <property type="entry name" value="SRalpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000188">
        <property type="entry name" value="signal recognition particle receptor subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="8">
        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="425" mass="47620" checksum="22CB17993C8DF8D2" modified="2019-04-10" version="1">MKKQFARTLKNLQIRNEVLRKPLRLKRQRVQSLLKRAKKIVCGTYQDVIPRASITHPGMIREQELSHPCALISFRTNLRLEHCPETLGEWMFKTKRNPMIKNLVVEVYSPCSVAWWAAKTLSEADIEPVLEKLKDHLIGKNVASEIATKLCQSVGKKLEGKVVGTFEGVSTTVRNTLTESLVQLLTPKRRLDVLRDVVEAKTSGRPYTMAFCGVNGVGKSTNLAKISFWLIENNFRVLIAACDTFRAGAVEQLRTHMHHLNALHPPENHKGRTMVQLYEQGYGKDAAEIARHAIEFARKNDFDVVLIDTAGRMQDNEPLMRALAKLILVNEPDLTLFVGEALVGNEAVDQLVKFNRALANHSTSNKPQVIDGIVLTKFDTIDDKVGAAISMTYITGQPIVFVGCGQTYTDLRRLDAKAVVNSLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QTF6</accession>
    <name>A0A3R7QTF6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RED-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003789</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001511">
        <property type="protein sequence ID" value="ROT77549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QTF6"/>
    <dbReference type="STRING" id="6689.A0A3R7QTF6"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="4">
        <location>
            <begin position="81"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="311"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="194"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="644"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="663" mass="73821" checksum="6E2D824B81F80ACC" modified="2019-04-10" version="1">MPQGGEEVFSNPLAPPGETLVEERPQRLTNADFRKLLMTPRAPAGSQKEPVSSVGAKTSSAEPPTQRRENKDDVRAAERKKKKSYYAKIKKEEEEKMAELAEKYRDRAKERRDGKNPDYQAEDPSQAGMGGYRAVAPDLKSGLDAAERRKQMIQESKFLGGDMEHTHLVKGLDYALLQKVRSEIQLKESEVMVEVEKPAEGTKEKKPPPVQPPMPPPQEEDELTFKTNVGRRIFNAVFNSKQSDFVDLFLPGRMAYAIDLDDEVAESDIPTTIIRSKADLQGIENMQATFTTNDIVIQKLTQILSYLRTGRANKKQKKKDKGKNEAAPRVGALPHKPKLPNHKYSSHPMPLHSHSQHNSLHIDKLSLNRKSPTCRQSSTCSTTLAHTDDSTGTWLIRGHLTYTYRLSSDCEHDMECISKTSRPRWRVGISIINNEAMQGQTRRLPQCDPYVLSFTHHSDLKAHVTSTRLRLSSYSSHASSQDADYPKPSGSSPRTNLQSDSHRQTVPTYRIPNVARASGPSLCPVILGPSLLITMRELTHSRATCESFFSSSFIFASFPPLPSPPPSTLYDLLLPAFLHLFIFSFSSLSSFPRLSPNLTFHASSFAHWLFSAASLPCAIYPLTPLLADSDPSLTSSSLLLPSSPHTSHSALPHLLPSRSTSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYM3</accession>
    <name>A0A3R7QYM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Engrailed-a homeobox protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023233</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000665">
        <property type="protein sequence ID" value="ROT83590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYM3"/>
    <dbReference type="STRING" id="6689.A0A3R7QYM3"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050720">
        <property type="entry name" value="Engrailed_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341">
        <property type="entry name" value="HOMEOBOX PROTEIN ENGRAILED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341:SF6">
        <property type="entry name" value="HOMEOBOX PROTEIN INVECTED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="21470" checksum="D210BD8928E37055" modified="2019-04-10" version="1">MALEFERQQQVASAAPGPMASPAMVMAAPISPALPPTPPSHDARSPPPPSPRSPHESKLPLSPPPTAPSPRSLPFSIENILRPDFGVTRLPAERPSGVRTPELLLRTPPKTPESVRHDFPVDLSQKGLSQSEHAKLCQANAANKYPDNPEALANPKVPADDNKWPAWVYCTRYSDRPSSGESSPPASLCGQLAAWRLCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYR3</accession>
    <name>A0A3R7QYR3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000634">
        <property type="protein sequence ID" value="ROT83761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYR3"/>
    <dbReference type="OrthoDB" id="6376497at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="13505" checksum="5A10AB88380FDA4B" modified="2019-04-10" version="1">MQNKEIDNICINPFRLFMENVPVQTTFEDLEKLFTTASEVVYMPNRCLAHMIYKSKEEQRRFSERLDDIEIHGAKMTVLYVDNTPNAIGEKKNYRKLRLLRRKRSKRNYRNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJ97</accession>
    <name>A0A3R7SJ97_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein singed wings 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018791</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003449">
        <property type="protein sequence ID" value="ROT63340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJ97"/>
    <dbReference type="STRING" id="6689.A0A3R7SJ97"/>
    <dbReference type="OrthoDB" id="6343311at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018761722" description="Protein singed wings 2" evidence="5">
        <location>
            <begin position="22"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="444"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="56330" checksum="6796D2E273419663" modified="2019-04-10" version="1">MWQLRLLGKLILVLLGASTWALTLSIPEENSIQPTHSSSGPCHVVEPTEIVCRGMQSLEEVSSNIPEELRAQVTKLTLENAVQGVWTRDDLVKLPSLHTVVFNHSYFSEWELPTRPDAPSLSRLILEDCWNNDTLKTSKMRSTLSLTTETLAGLGGLEEFHIIDCYVLDLNLSTIETVKPLQLLNIVGGGLNCTKDKLWMLEWMDEGRANITNTTKCFVVSSGEMTLFSTRYSFNDHQFLLCMKYVKETERDCPSQCQCNVQGFKESQYPIIHLLCERVGLTQLPEVIPRCTTRMQFGWNNITDINTLFTNKNYRRMDSILLNNNQISYINGDLFYNYIKGRPLDVYINLANNKLTTLPIKEINRIYDEARKTSQFYPTFNLADNPWNCDNCSFLPEFQKLVYYQSTMIPDYHDIRCPSDSEHHPKERLILIDVESQCSPGPPLLSLIDILNITLALLLLLLIINFLHNFYQYRRHGKLPWIIIRMPFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLV3</accession>
    <name>A0A3R7SLV3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002964">
        <property type="protein sequence ID" value="ROT66285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLV3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="57174" checksum="5B7662C499CC9B0F" modified="2019-04-10" version="1">MMEMPQLCNSARKSYLFLPGSFFLPGSFPSEIFFLRDLFSFRDLFPSEIFSFRDLFPSGIFFLPGSFSFRDSFSFRDLFPSGIFFLPDLFPSGSFSSGSFSFRIFFLPGSFFFLPGSFSFRDLSFRDLFPSGFSFLFFSSFGIFFPSGIFFPSGSFFPSGVFFLPGSFPSGIFFLPDLFPSGIFPSGSFSFRIFSFRDLFFRDLFPFSFRDLFPSGSFSFRDLFPSGIFFLPGSFFPSGSFSWIFFLDLFPSGIFRDLFSFPGSFPSGSFSFGIFFPPGSFSFRDLFPSGIFFLPGSFFLFPSGSFSFRDLFFSFRDLFPSGIFFFSFRDLFLPGFFPFSSGIFFLRIFFLPGSFFLPGSFSSGIFSFSSGSFSSGIFFLPGSFSFRGSFSFRDLFPSGIFFLPGSFSFRDLFPFSFRDLFPSGIFFLRDLFPSGSFSSGIFFPDLFPFSFRIFSFRDLFPSGSFSLESFSFRDPSGIFFLPRSFSFRDLFPSGIFFARVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMU8</accession>
    <name>A0A3R7SMU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative sodium channel and clathrin linker 1 isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014144</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMU8"/>
    <dbReference type="OrthoDB" id="551053at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045162">
        <property type="term" value="P:clustering of voltage-gated sodium channels"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038911">
        <property type="entry name" value="SCLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35970">
        <property type="entry name" value="SODIUM CHANNEL AND CLATHRIN LINKER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35970:SF1">
        <property type="entry name" value="SODIUM CHANNEL AND CLATHRIN LINKER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0407">Ion channel</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="231"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="596" mass="68846" checksum="7FCAFBB10141C5DE" modified="2019-04-10" version="1">MEKEYLIKDYEEAVRKQALLIARQQALIDDLREELSTQQTRSASTNKENQKRIEALLQQIQSSTIQESGEEILLLKKEVETAQKEKELCQAENSRQTLEIERLQQELVGLQSATSDAQIPLQGQFSDEYAKVVEALEEETNRLRAELNRLEDEKIEILKVNIGLKKTVSSIETTLEQEVQKNQILKSTLEERGSASQEIRDSYRTLNAKFLEQSEDLRTLIAQTEALQKSKDQMTKVLSNVKEKLNDAQKRVADSLRIAEDSLVEKDAALLREKHALNEVRRLESTVASLMEEAGQKAKAEVNKIKDDYNANIKKLSQEVAQLEMKQLECDRSLRERKKMAEEVERLMAELCNKKEQHRAETLNLHDRINILESKITNTIAEKKSVSDQNVLSMREYEQQKEELFHRIQELEQRLSTSRSECEALRLECEEIRSANADATATLERAKEDGESSEKFLKRQLRLKTEELEELSSSSRVRLDALNSTHQEVVTQLQDNIASLQESYTRLQVQMNDQRKESELKMSEVSRRLQECQSKSQQLVRSLHEASTNLAIARDLNSHYEKRIQDVEDRLRASEKRFVTLRSGSRQDEGLYKPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSY1</accession>
    <name>A0A3R7SSY1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002014">
        <property type="protein sequence ID" value="ROT73607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSY1"/>
    <dbReference type="OrthoDB" id="6358248at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="20901" checksum="FEB465A2D22D818B" modified="2019-04-10" version="1">MPLVPSLPKTVEEEGVSLVNIWSHALRNQKDEGGSPLVRSEPGPKTILAPSPFLMMNLVPQDAAHPLYSNKYADLRTEFLLDYMLEADVSPDDPKMAEEEGLTVPNLFGKSITFRKDADGKVSIEGQAVEDSKKLSDGLVVYQLPGFLFDHRERVREAFELLQKETPRYGPMGRPLNMPMPPMKPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUI4</accession>
    <name>A0A3R7SUI4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_005751</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001745">
        <property type="protein sequence ID" value="ROT75695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7SUI4"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="10">
        <location>
            <begin position="723"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="11">
        <location>
            <begin position="1210"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="465"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="88"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT75695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1329" mass="150757" checksum="12A17E396D2794DA" modified="2019-04-10" version="1">MSKVPEPGSESGAVGEAQVILAGNGGEERAAEAGKQALPDVVDLFRKVMSKLDKTGEDMNRLSEAMRKNHKEVNSAFCRLKDFVWCGLEEVREEARRHTDDAGTALREVTEREMQACREEISALQLALKEQSTTMDRLQERKMEPPEEERLPKDVCSDPGEWMAWQRDLPVGASCKRETEKARNRTCLQASPHDCQRWRKPSEFDGKVAWEAYLAQVELLAGAQDWDDNEKALQLISGLRGVALEVLAHLTSQQRTVYSHVVGALQRRFGHHHQAEMYLARLKARVRARGESLPQLAQELETLVRHAYPAAAEDMVTVLTRDYFVDALQDRELQLYIEQAHPEDVQVALARALELEAFLRTSVLGAALERVSGPAHLSGGVARGTVWCYPASESDRLPVYLLEVRQEGAPPEYCPRGRRTRSLERKPISAFQPCCASCGRYGHSVTQLPVLALKTCRWETRRGWMRGPTASPRSSGPTQCNLSPYSRSNGPYKRNRGWEAMSNDNGYVDTGAEKTIMRPDVLTARDYHEEPRQLCGVTGHCTPLRGPVEARFSVGGSEEVLPVYVAEMEDPCLLGIDYLMQVGACIDLKKWKLRIREKEVPLSLGVAPAEVVMAVCECIASDTEPKVTFELSGKLENHDCMIESIEPLEQADDSEEVTFQKRLPGNEGVVNDISLPDHLTDLARRSAIHLDHQQQERLGSTLTRYADVFSKGDLDLGRTGLVQHHIRTGDALPIKHAPRRIAPARLTKKDGTKRFCVDYRSLNNVTAKDSYPLPRMDDTLDAMAGARWFSTLNLKSGYHQVEMAREDKAKTAFSFGQGLCQFTVMPFGLCNAPSCFERLMERVLEGLQCRTALVYLDDIIVFGGSFDEELERLEVVLRRLRAANFKLSPKKCLFFQSEVPFLGNIVGRDGVKTDPQKVAAVQDWPVPTCVADVKSFVGLCTYSRRFVKQFAQIASPLHQLTRKGALKSTEHFHPYLYGAKFLIRTDHAALQWLKTLKAPEGQLARWLGRLEQYHYEVQHRPGRVHNNADSLSRRPCEPECQHCLRREERVACRQLQVWGDSVDAEERWRQVQREDDDLTPLIKWMEASPERSGWPQVTAESPVTKHLWQQWAMLRLENGVLQRRWDDARGRPSYWVVLVPHTLRRDLLHELHGGITSGHLGVKRTLTRLRQRFYWVGMRRDVQEWCRTCEVCCARNGPVKKNRAPFQLYQVGAPLERVAVDIVRPFPVTTRGNRFICVVMDYFTKWPEAYALPDHEAETVAEALVNNFITHFGVPCELHSDQGREFESVVFQECCRLLGIKKTRTTALRPQSDGLVERFNRTLIHEVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SW96</accession>
    <name>A0A3R7SW96_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001403">
        <property type="protein sequence ID" value="ROT78269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SW96"/>
    <dbReference type="OrthoDB" id="10062605at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="13684" checksum="A9AF444CE005628E" modified="2019-04-10" version="1">MGNCCCTTCLRPLRWTEGVRKEWLSRVPGVSEEGAADPLRSAEPLDDGPLTGTHSREEIESLIRARCDLGCPPSKDDLAKLLPPRTHPPATPPPSPSPHRLPPPAAASFFSPVCSVSLLPSYSLTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWN4</accession>
    <name>A0A3R7SWN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001319">
        <property type="protein sequence ID" value="ROT78863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="697"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="796"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1077"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1398"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1316"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="514"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="567"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="715"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="824"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="915"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="957"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1001"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1034"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1094"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1123"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1175"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1201"/>
            <end position="1216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1424" mass="154244" checksum="44BE7DB5A89D3D01" modified="2019-04-10" version="1">MLMKNLRRQQEEEEREQAGGGRRQSLLEICGQSPPPATQGPEGSPAGEGQGAKESQGHEGKIGDLMQEISSTIFSEETGVVSNPLYTSLINLSSPSLKSAPNGDLHSPSHTSGSAAKASLAAGPPSEALAGGRKENAKVNPVPKPPRSGFPERSQSWEPPGSQGPDDGTQVRLKRQSFSSFGEGSTLACGGSGESSEDDDVFGEVTPEVKEDLAEAKNQLLSQKDSYEKRSDSEVSDADSAENSRRNQSKVAKFIKRFESIDQQSNGSRSSRSDEEDDEEEGQPEKTDDVYEEDLNKMKLERGLSIDSQSGGDFQASELIGSIARDSPQSLESDKIPLSFSDESAGTDKEESSSENGDREPHSNGISTSSEDQFEKLYLELSQESPDHTNGFGNTNGSEETTQPNGTDPGQRNGETTPKDPLVEENEANGEDAVDSPETTPMKRVNSIIKKKNKDSTSSGTVKRVQFNLDIQTVEPQPVSDDRTPHPPQPKEKKEPPTDQPKKKSTKDPTPAKASPPPEVPPNSPVKKPSSPASSPTKKKSPDSPSKKGGRSSPSPTRSPSKKKGILSSLFASSASKKGAGSSAKEETTKGDDATNIPKPQTKEASGLQRQTTLDMNAPVVMSVRDGHVLAFMPKSSAPSTRISLYGLSVMPVLGGAHAHALTLNRGSRCMMLIKLGSREEMMRWINTLSDEVIKMTPTDQRSGLTLFPTPRQDSSGKEEGARDEEGKEGDAEEEEEGGEEAKNRVNEEEVSEVTEVREKDDVDDTDGAVVMRKEVASLQDVIDYRVQMEEREKFTYFGSGGDATDKGTSQINKENTLRDTDRTGSQAPESKSATPKGEPKPKDLANNSHPPLRRLSGQARPSSQTDSDTVDNFLMASAFPEPEGKRAAVNGHRPLARLFSQPRAPAAVPASRKTPGTASNEGLTNGVSEVSSSVPRGEETSAERRRTHNDNDGHSDQISASPRGPTTSRDPSRNHVAAAGASSHINSHARGPSRAAALLEPRRVEIVEQEVRPKATSESQRISRRGASGGGGSDRRKEEEERRNTRAPTPVKDDIDETPTITWSVAATREKFELLCSVSGEDKLGKLTTKTPISRKRSVRKKRSLDGTGTPRRQSVKRSVRRTLSNMESNSSLDAEDRSEAEPERRPQSDGLRLPPVRDLRKNFEAEPTRSPTPTSPSKPLSPTPSKASAAGSPVKSPVRRTSNILQQDATSPASSPEPGFISSKAINGRPKGRIRDDDKGPVTRSLLATRTTPQPDSEVVICWRGPYIAQEPGSEHCLELRGDRQARDHLAAKAESEQAVLANISNAFLAKRRLLAKEVMMARIQERLSQLEETMWDLQAAMAELDNRKARNSLEWGSLERSLRTAEEDAAYWQTRLGQVQKEAQETREKLATALAKGLAQHLGDEEDPRQDALGGTEESQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZ52</accession>
    <name>A0A3R7SZ52_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_024241</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers mannosyl residues to the hydroxyl group of serine or threonine residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMTC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01000799">
        <property type="protein sequence ID" value="ROT82602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZ52"/>
    <dbReference type="STRING" id="6689.A0A3R7SZ52"/>
    <dbReference type="OrthoDB" id="1658288at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013618">
        <property type="entry name" value="TMTC_DUF1736"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052384">
        <property type="entry name" value="TMTC_O-mannosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44216:SF3">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE TMTC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08409">
        <property type="entry name" value="TMTC_DUF1736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 16" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1736" evidence="18">
        <location>
            <begin position="247"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="563"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="600"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="634"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="668"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="702"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="736"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT82602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="792" mass="87899" checksum="A4E7919DD65255AD" modified="2019-04-10" version="1">MILVDDDNEIRKGLPLRTRAIKTNPDVLPTTPISQLLWDDFWGTPLTHSGSHKSYRPLTVLSFRLNYMASEFQPRSYHVTNVALHVAATGLFAVLARTLTPHARLARTAAPLLFAAHPIHTEAVAGVVGRADVGAAIFFLGALLSYMRYCGCSRGNVNGSAGGRVGRKAWLGAALVSATLSMLTKEHGITALAVCAAYHVFVHARLRPRDLLSILTERRHRGVAEGLAALGAALVVLLSCRLAIMGSQPPEFSPADNPAADCDSPAVRSLTFFFLPAFNAWLLLCPYTLSFDWSMEAIPLITSIADPRNLASFALYAVLALLAMTVLLSLRRRRPGEDAASGETTTSGDVTVMGLALMLLPFLPATNLFFYVGFVVAERILYIPSMGACLLVGWGAHLLHARARTARARRLLHGALIILFLLFAARTWSRNRDWATEENLYRSGIAINPPKAYGNLANILSSQGKKEEAEWAYKKALSYRSNMADVHYNLGILFQEQKRYEEALQEYKLAIQFRPRMAMAHLNMGLVLGLMGQKAEAAEVYRHCSQLDGSGLKDPRTHEATKISALFNLGRLYADDGNFERAIGVYQEAVEKMPPHYQPQSLYNMLGEAFFKLEKFDDAERWYLEALKVKADHVPAHLTYGKLLAKMQRIGEAEEWFERAKTLAPNDSTVHQHFGQFLSEVERHEAAADHYVKAAQLAPSEYEIIFNAANTLRQAGRNKQAEDYYRQAVLLRPQEATSHMNLGAMLHVNGKLLEAESSYLEALRLKPDDSITRTNLQKLRHLLAKKGISPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SC53</accession>
    <name>A0A423SC53_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative IQ motif containing GTPase activating protein 3 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020403</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003989">
        <property type="protein sequence ID" value="ROT61786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SC53"/>
    <dbReference type="STRING" id="6689.A0A423SC53"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903479">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="490" mass="54186" checksum="48115A66B4A0C8AE" modified="2019-05-08" version="1">MLQIFYPETTDVYDRKNMPRVVFCLHALSLYLFRLGIAPQIQNLYGKVNFSEEVMQAMMKELSKYGCQLPQFGKIGGILANELPVDEAALHAAIIAINEAIEKGEDSELLGTLRNPTCHLEKVLDENADSYLQCLSDAKMHKKEMAINKSRDQDYIPDAYDELLTQAEIQGHISYVNGKKSEDAVKENTNALFKALTSPVLGLKGVKPDFAGEYLKALAKELEEKETQGGNQSFNHSLNVSLLPTILSKSSVQAIIASVNEESLSKLKLLQGLAEVNRSLEEGTPQETLKYLKSLGPSIPTLLDFGAPLYHEEMAAIRADAQADLNLEEIQGGVRMLSAVARVNAALDTHNPEEVWHYLSDPQTHVQGLERGHAREYFSSLHEARQAKIASGEVCTLLTYLDLQQVIDEVNDRLQEVNDKVGALTGVNEAVIAGGVQDTMIALQHPALQLPSLSPTDSLHYYQLLKLLKTTKCEMLGDSAAELWIEDIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCQ1</accession>
    <name>A0A423SCQ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020153</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003863">
        <property type="protein sequence ID" value="ROT62028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCQ1"/>
    <dbReference type="STRING" id="6689.A0A423SCQ1"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170:SF6">
        <property type="entry name" value="CONTACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44170">
        <property type="entry name" value="PROTEIN SIDEKICK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="884"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="248"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="337"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="534"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="651"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="767"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="615"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="843"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="975" mass="106332" checksum="1316EC8F5F31D6E5" modified="2019-05-08" version="1">MAEIIGMCSARVHNARPTRLPLASTPLALPSTRRKVDFPPARALSYLIVSDFRGPLSRADKRCQDVIATSDGGVTLAPGPPWLFSGPGARRRRAGESLLTWASRLCLQVVGDASGKESFIIPSLFPPPRLLPLFQPSPSPCISPTPPFRYLSLFHFLFSSAVLNYTLSPPPSRFSISFSPNFFYSFSSLFSPYSAVIASETEHELVDEGSLMVKHVDQSDGGQYTCEAWNLAGSKTTVPVNLYVHIKPNFLRGPKDTVTLTDRKVEFECQVSGDPPPQVSWRRLRGPLPEDRTEILDDHTLRIGRVTPGDEDTYVCEAVNVVGTARANATLTVYTAPEFLVRPQDVKASVGSSAAFECLAVGRPSPLVVWSRQDDHNLLLPRQDTPSGEPDDQPNVWVNAEGTLIINQVTRELSGWYSCAAVSAAGSLVARALLDVPAPTLHPPPVISVRPRNLTVTPEAVALMVCQAEGAARVTWTKDGRLLPEDDARITLLGSGRCRSAIPNIRSILPSLSSNPPPPYTLPPLPPFRSLSPIPLPCVWRARNSTTLTLAWGPPEQEGASPITSYILEIWNGSGQWTPLEEHIPAESYTLTGLKPNTQYRAVVRAMNMHGVSASSPVSGPLVTAGGGRPGGEGAKETNNDPEIRAVLAHPLVTLMPPTPISSTAIKLQWKVQEFEDYMDGFYVRYRDLSSGTHRFEMEAVTRSGAAHQAASYTVSDLAKFTEYEFFIVPYHRNIHGHPSNSRIAPFITHRFLTNNPLLPPAVPSAPPSGVESLVLNATSVVLSWRPPPREHTNGRITKYSVWLFVNKTVPHSNLTLEGNLHTLTLYNLTFGKHFTATVAAQTKAGQGPTSGGHTWLQDPSASSGSGEPKRVPSPLMAVLRETWFIGAVGAAGFLALSVFVAVVCYRRKRNEKRAMGVLINRRQYGSDECIEEVAPSVLPICPPPLFLGFMASLKTPLVLPSCVVSDERIQRYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SG35</accession>
    <name>A0A423SG35_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019013</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003489">
        <property type="protein sequence ID" value="ROT63113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SG35"/>
    <dbReference type="SMR" id="A0A423SG35"/>
    <dbReference type="STRING" id="6689.A0A423SG35"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8 9" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="11">
        <location>
            <begin position="10"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="12">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT63113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="13448" checksum="01F657958F9A4EE3" modified="2019-05-08" version="1">MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKNRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGSQKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGN8</accession>
    <name>A0A423SGN8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidylinositol N-acetylglucosaminyltransferase subunit P</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_018745</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PIGP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003447">
        <property type="protein sequence ID" value="ROT63376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGN8"/>
    <dbReference type="STRING" id="6689.A0A423SGN8"/>
    <dbReference type="OrthoDB" id="690928at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052263">
        <property type="entry name" value="GPI_Anchor_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013717">
        <property type="entry name" value="PIG-P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016542">
        <property type="entry name" value="PIG-P_GPI19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08510">
        <property type="entry name" value="PIG-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008765">
        <property type="entry name" value="PIG-P_GPI19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="PIG-P" evidence="9">
        <location>
            <begin position="12"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR008765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="127" mass="14390" checksum="7C6027E15040E1E2" modified="2019-05-08" version="1">MGEHTPAPSPGRSYYGFVLYLLGWAGIISYLAWALIPHSYLAALGLTYIPQPYWALAFPSVIITLVLIFVFFIYPSLNLILALPPHDIRNITDNMAMREEDYPRVEEYGVPPVCDLPISQVCRALYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI69</accession>
    <name>A0A423SI69_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003359">
        <property type="protein sequence ID" value="ROT63901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI69"/>
    <dbReference type="STRING" id="6689.A0A423SI69"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="41911" checksum="70ED5596C55497E3" modified="2019-05-08" version="1">MITAFLFTYLFFLISTLFPLHLLPFPSRFFSPFFSYPLHFSSLLPFSNPFLPPIPSILHPFLPPFSFYSPSIPLPILSILHSFPSPSLSPSFFFLFSIHSSPNSVHSPSFFSPPPHSFHSPSLFSLLFPSILPPSSPLPPSHSFHSPPLPIPSSSHSFHSPPSLLPPPPFLPPPSHTHLLNRRRRKRSRERYPTAVLPPPPFLPHSPSLSPSPPHPPIPPLPPPPPSSLHSSPPSPGESERCPTAGPPPHPPPIPPFLLPSPHSQSPFPPIPHLLHRRRREKSRKIREVEKDVQRGPSTLPPSSPLSLPSHFLLFSPFPILPSPHSSPPPPPPPFLTSFTVAEEEKSRRCPTAGPPLVGMIREMTSVVSPSVSETVTTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI79</accession>
    <name>A0A423SI79_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003359">
        <property type="protein sequence ID" value="ROT63892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI79"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="810"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="906"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="947"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="959"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1066" mass="113154" checksum="E3F07F33305AF6F0" modified="2019-05-08" version="1">MATYDIRVVPRPAAVTPRPRRPQRRPQPRPRTAPTPSTPLNPAPDALNPHPDALNRPDALNPAPDAPSTPPPPPRPQPRPLKPPPDALNPAPPPLTPPRPLSPPSDALNPAPTPSTPARRPQPRPTPSNPPRRPQPAPDALARPRRPNPPTPSTPPRRALTRPLNPAPTPSTTAPDPSTPPPTALNPAPDANPSTRPRRPSTPAPDAANPRPRAPHPPRRPSTPPPTPSTPPPTPSPPTPSTPPPTPSPAPTPLNPAPPPDALNPTPDALNPPPRPDALNPAPTPSNPARPDALTPDALKPRPHPSTPPTPQPRPDALNPPPDALNPAPALNALNPRPSTPPPTPSTPPPTPSTPPRAHPAPDRPQAPPPTPLNPPPTPTPPDAPNPPDALNPAPTPQPRHDPPPPPRRPQTPPPTPSTPPPTPSTRPSTPPPRPQPPPTPSTRPDALTPPPTPSTPPRRPSTPPPATPPLNPPPTPDALNPAPARPQTPPPTPSTPPRRPQPRPTPFNPAPDALNPPLPDALNPAPQLRPRRPSTPPRRPQPRPRRPQPAPDALNPAPPPRRPHRPPARRPQPPPTPSTPPDPQPAPTPHPPRALNPARRRPQTPRLNPAPDALKTPPPTPSTPPDALNPAPDALNPAPDAPTPPPPRRPQPRPRRPARPHPAPRRPQPAPDPNPAPGPRPALNPAPTPSTPPRRRSTPPRRPQTAPPLPAPTPSTPPRRPHPAPRRPNPAPPSPPPPTPSTPPRDALTPPRRPQPPPTPSTPPRRPQPPPPPLTRPRPSTPPPTPSTPPPTPLNPAPDALNPAPPDALNPRPDALNPAPDAPQPRPPHALNPAPRPQPRPRPPSTPTTPSTPPPDAFNPARRPQPAPRRPQPRPRRPSTRPRRPQPDALNPAPDASTRPRRPPDPQPAPDRPQPRPPTPSTPPPDALNPAPRRPQPPPPDPNPAPDALNPAPTPSTRPRRPQPRPRRPQPRPRRPQPAPTPSTPPPPPTPSTPPRRPQPRPDALNPRPRRPQPPPPDALNPAPDALNPAPPPFNPAPNALNPAPTPARPWQCLRCLWVADPERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJW7</accession>
    <name>A0A423SJW7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PIH1D1/2/3 CS-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003239">
        <property type="protein sequence ID" value="ROT64535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJW7"/>
    <dbReference type="STRING" id="6689.A0A423SJW7"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026697">
        <property type="entry name" value="DNAAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041442">
        <property type="entry name" value="PIH1D1/2/3_CS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21083:SF0">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21083">
        <property type="entry name" value="TWISTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18201">
        <property type="entry name" value="PIH1_CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1D1/2/3 CS-like" evidence="2">
        <location>
            <begin position="71"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="179" mass="19349" checksum="A41485DE7CF6F8A0" modified="2019-05-08" version="1">MYLTPASLAGITKGSNARSGTDVAKSAGCRESTKTKSVSGNTSLDSLLGDVWEVEEVKLGQCVEPADPRPQPEYEVNYRQRVTANQVYLPLSSLAPDGRGEEDLVVRIVLPGDLFTDVNLEVTSSTLRLASPNHLLHLPLPRQVDQRKGVATWDPNAYTLVVTLPVSAQPLLRPASSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK73</accession>
    <name>A0A423SK73_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003233">
        <property type="protein sequence ID" value="ROT64563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK73"/>
    <dbReference type="OrthoDB" id="6365500at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="24168" checksum="9C5FD97C26C374F9" modified="2019-05-08" version="1">MRSHARTFVEAALLLRLDGRAGAPRLLGYGAEQPMLLLESLLGCNFLFLLQDAAAPLSLHLQVVKRVVQHLREMHAIGIVHNDVAIPNVVVHVDADYQLRDVRLVEFTVACPSGDSLALDVEPGAFPCVAPDVARGGASTPAADVYSLGALLRELSQAQEAARLATQEDPQARPDLGALEELLSHAVAWQKNKEKRRKGKKAKRHRGQEGAAASREDSGRQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLX0</accession>
    <name>A0A423SLX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003133">
        <property type="protein sequence ID" value="ROT65149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLX0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019164691" evidence="1">
        <location>
            <begin position="16"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="43312" checksum="C6DB6B22023BDA95" modified="2019-05-08" version="1">MSLPLSLSLLTLSLSLPPPHTLPVYFLPPFSPPFSLFLSPSLSFLDSSPPLSLPPLPVPPSPYLPIPLPPFPPPPIPLIIYPPLPISSFPPSFFSIPISFPSLPPPFLLSPPPLPPTLPRFLHPSPPPIPPFPPSHPPFSLPSSSSILPPLPPFLLSPYPSPSRSHLAETFVFPRKPPPSPLPFTIKGINFHYLFIFPLLLSSLSSLLFFPPSLFSFFSSLPISPAPLLTFPPFSSLTFCSSFSPSSTYSPLSVPHSPLLYILLPPLLLSSPLSFLSLSRPFHLPYPLLTPHTFPHTFSHFLPNPTLSPTFRRHSLSLISTILSLLSLSPALHTSIPTSHLPPFPPHFSSTSLSLSTFLSIHSLSFSLSSPLSTFPPPPTRPPAPPPTLFPIHILSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPN8</accession>
    <name>A0A423SPN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002985">
        <property type="protein sequence ID" value="ROT66161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPN8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="362" mass="39452" checksum="9A324F7937A1587C" modified="2019-05-08" version="1">MSLYRVRRNTSSPSAGAPWLQRPLRATPFSVGVAPPRPGTPASTLLTHRRKKMRIWQPNSRVRLQMLKVEVLPTVVLLQVTRQVSTEVTCNSLPCSQVGGRGYRSCPVLPSRPGTPDSRRRAHYLETWAEAAREPGGGAADLRSADLPPAVLQRRRGCGPVTIKVLNNAHLDVLNLTRTDEESSCCAYTPTHLEVCFPPGNMVGVVQGSPMEYTVHNPSGDLLFLLQKEADTLCSRGGYEVTSADRFTPITSFTSTQVTSADRFTPITSFTSTQVTSADRFTPITSFTSTQVTSADRFTPITSFTSTQVTSADRFTPITSFTSTQVTSADRFTPITSFTSTQVTSADRFTPITSFTSTSDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SS06</accession>
    <name>A0A423SS06_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative heterogeneous nuclear ribonucleoprotein A1, A2/B1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014956</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002871">
        <property type="protein sequence ID" value="ROT66956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SS06"/>
    <dbReference type="STRING" id="6689.A0A423SS06"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48026:SF14">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48026">
        <property type="entry name" value="HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="13"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="83"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT66956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="34752" checksum="CE20EA04C80102C3" modified="2019-05-08" version="1">MVKEEHSEPEQMRKLFIGGLDYRTTDESLKAYFEQYGEIVDVVVMKDPKTKRSRGFGLMGGLSNKACCPRDEIGKPESGVTVKKLFVGGIKDDVDEEDLRETFGKFGTVVSVSIPTEKESQKKRGFAFVEFEDYDAVDKACLHKNIQMKGKRVDVKKALSKNEIQMQQRGRMGGMGLEWVEVVAEMDLGLVVGTTIGETTRAVDGESGQVVHNQGGYGNQGPWQGGPPNNQGWNNQTNQGWGPQAGNYGGTPNNWGQGPSDFGNNYGQSYGGGPMRNQGYGQTNRPAPYSAGGAPGYNNPGPNNYGGAANMNQGPNRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUE2</accession>
    <name>A0A423SUE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Opsin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002761">
        <property type="protein sequence ID" value="ROT67773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUE2"/>
    <dbReference type="OrthoDB" id="6412312at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="151" mass="16943" checksum="E05062D454D7EC09" modified="2019-05-08" version="1" fragment="single">MANATGPQMAYYGQQMGTFGYPEGMTVVDFVPETIKHMVHEHWYNYPPVNPMWHYLLGVIYIFLGFFSTTGNGLVIYLYMKAPGVAGNHENITPLVTMLPALLAKSASCYNPFVYAISHPKFRQAITVHMPWFCVHEVEKSGGDDTKSNST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUT9</accession>
    <name>A0A423SUT9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="3 13">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_013959</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterotrimer composed of RABGGTA, RABGGTB and CHM; within this trimer, RABGGTA and RABGGTB form the catalytic component B, while CHM (component A) mediates peptide substrate binding. The Rab GGTase dimer (RGGT) interacts with CHM (component A) prior to Rab protein binding; the association is stabilized by geranylgeranyl pyrophosphate (GGpp). The CHM:RGGT:Rab complex is destabilized by GGpp. Interaction of RABGGTB with prenylated PTP4A2 precludes its association with RABGGTA and inhibits enzyme activity. Interacts with CHODL. Interacts with non-phosphorylated form of RAB8A; phosphorylation of RAB8A at 'Thr-72' disrupts this interaction.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="3 13"/>
    <dbReference type="EMBL" id="QCYY01002737">
        <property type="protein sequence ID" value="ROT67923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUT9"/>
    <dbReference type="STRING" id="6689.A0A423SUT9"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000004">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5 13" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="14">
        <location>
            <begin position="18"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00062019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT67923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="333" mass="37058" checksum="086FEB3C13D4C344" modified="2019-05-08" version="1">MGSHPKDVVITDEHPKTLLYQKHADYIVGYSKKKDDYEFTMTEHFRMSGMYWGITALDLLNQLDRMDSTEILDFICKCQDKGSGGFSPSIGHDAHLLYTLSAVQILVILEALDKVDVEAIVKYVAGLQNEDGSFSGDQWGEVDTRFSFCAVNTLALLKRLDAINTEKAVEFVMRCQNVDGGFGTRPGSESHAGQIYCCVGLLSITGQLHRVNGDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLTMLGRLHWINADKMRVFILATQDAETGGFTDRPGDMVDLYHTLFGLAGLSLLGESSLKPINPVFCMPQYVLDRISVTVQIMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1E6</accession>
    <name>A0A423T1E6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002445">
        <property type="protein sequence ID" value="ROT70287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1E6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="559"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="664" mass="71249" checksum="B6941C015ED0ACFD" modified="2019-05-08" version="1">MTSSDKELLLARRSLRRGSTKPSEIGLAVKVALASGRNAGDVGKTGDASLPPPSPLRGLHLPHSLAFLIARLLLPLPNFPSPLLTHILPPFLPLPPPSHSTSNALLSLLALPGHSPSLLPSYPTPLLPLLLLLPPPRPFPLPAPSYPSPFPYYSLSCSLFLTPPTPSLPSPAPSYPSRFPPTPPFPLPSSLPSPAPSPCPLAAPLQLPAHIDLSLPSLPCLYINPPPSPHLPYPSISSPSPYPNFLILHLPLPILLLPSSPSSFSPPFPLCTKLPLPSSISLPTLPSFPIAERSEVPPTFLPPFLHSSYSPILTSLQRIPLHLASPPPPLPLVPLERTPPKPPPPLSLTCFIAKDYPNTFLLHSSPPLFLVPSTPLLHSPFLHSLLPTPIPLHPLLHSPTPFPYLAHRLPYYPFSTSPPPSLRTPYYPPSPPPPPTPYSPTPPLHSPHPPLLLPYSTDSPTPFSTPPPPPSLRTPLLPPLPSSTSLPPTPTPLHPLLHSPTPPPLLNRKGFPTTPLLPTPTPLPHSSPPIVKDSPTTPSPPHPPPSPCSNVKGLPYYPFSSPLPPPPTPHPPPTPRRHRMSCLGGTDSPRAKEPAVFALTLTLTLISMSIFFSLPLSPSHLSLPLSLLSLPSYPSFPNPPVPFYLIHHSLLPCPFSPFLLILNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1K3</accession>
    <name>A0A423T1K3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011281</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002426">
        <property type="protein sequence ID" value="ROT70432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1K3"/>
    <dbReference type="STRING" id="6689.A0A423T1K3"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07141">
        <property type="entry name" value="ALDH_F1AB_F2_RALDH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000001">
        <property type="entry name" value="Mitochondrial aldehyde dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="53"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT70432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="57222" checksum="BD5C47BE7F69B231" modified="2019-05-08" version="1">MLRSVLQRTALIRAASKHSAPSTAAFSNAAIPQPITSPDIHYTGVFINNEFHKAESGRQFPTVNPATGEVIAMVEEGDKADVEKAVKAARKAFSLNSEWRQMDAYDRGQLLYRLADLMERDRVYLASLETLDNGKPYTNSVMVDVELCIRNLRYFAGWADKVHGKTIPTDGPHFAYTRHEPVGVCGQIIPWNFPLLMQAWKFGPALATGNTIVMKLAEQTPLSGLHVAKLVAEAGFPPGVVNVIPGFGPTAGAAIASHMDVDKVAFTGSTEIGHLIQQAAGASNLKRVTLELGGKSPNIVFKDADLEYAVEQSHFGVFFNQGQCCCAGTRIFVEDAVYDEFVERSVERAKVRKVGDPFDFKTEQGPQVDGEQMNKILEMIDSGKKEGAKLVHGGARVGEKGYYIAPTVFADVQDNMRIATDEIFGPVQQIMKFSDVSEVIERANNTSYGLAASVFTKDLDKANMFAQGLRAGTVWINCYDVLNAQTPFGGYKMSGQGRENSEYALQNYTEVKCVITKLPVKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1W0</accession>
    <name>A0A423T1W0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-1,3-glucan binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002421">
        <property type="protein sequence ID" value="ROT70467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1W0"/>
    <dbReference type="OrthoDB" id="6384109at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="42159" checksum="1BD478907F4337C5" modified="2019-05-08" version="1">MFHLNLDSELEYSGRRQVISNLRCARLIFLHRYEGVEYDVDYSFPGDNHLQIKVEIDLNENGQEVEATFFLDSEGIKARLSSAVLVAPDGFYAEAGLDDYNLKLRGGFKNEDTARGVQLEGEVFGKRFLIDTLFQSEGKRYSEGKLIIHTPFHGMEKMGGLFTWSNQNKKIMAHAELHLPSYTTPTITGEISLDLKKKINGYVTLDVAGEEFTLKCNLAGSSISQGYTGSLEFYTPFHAVSHVVLTGDIKMQALSFLDMEVKIDAPFATHDLKLKYQLSADKVSGEAFLQSTRLYNTIQLSLNLQGLSTGNVEADLTVNDNKINAHYTLAQSTFKFDVRTVIFGKERQFSIEAKYPSLENFQGVVAVTLEGEKHMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T402</accession>
    <name>A0A423T402_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002364">
        <property type="protein sequence ID" value="ROT70968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T402"/>
    <dbReference type="STRING" id="6689.A0A423T402"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000033">
        <property type="entry name" value="dnaJ homolog subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043183">
        <property type="entry name" value="DNJB2/6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45168:SF3">
        <property type="entry name" value="DNAJ HEAT SHOCK PROTEIN FAMILY (HSP40) MEMBER B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45168">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="155" mass="17389" checksum="ACB1BFE97876F056" modified="2019-05-08" version="1">MAKDYYKILGLSKDASEGDIKRAYRNMALKYHPDKNKSNDAEEKFKLVAEAYEVLSDKKKRNIYDQYGDEGLKGGMPGGRSTGGTHFTYTYSGDPRATFEQVFGTNNPFSHFFNMGVDGHGTHDVFEDMLVGGGSHVGVKTRRTFSFNPHDNNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4S4</accession>
    <name>A0A423T4S4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Schlafen-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002302">
        <property type="protein sequence ID" value="ROT71375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4S4"/>
    <dbReference type="STRING" id="6689.A0A423T4S4"/>
    <dbReference type="OrthoDB" id="10259112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="entry name" value="Schlafen, AAA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029684">
        <property type="entry name" value="Schlafen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12155">
        <property type="entry name" value="SCHLAFEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12155:SF41">
        <property type="entry name" value="SCHLAFEN ALBA-2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="SLFN_AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Schlafen AlbA-2" evidence="2">
        <location>
            <begin position="275"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="43361" checksum="43FDD4439CB56049" modified="2019-05-08" version="1">MQAVITGRKDQRSPSDGKQDKEDSTRGRKDFREERMKAQEKGFEFQENRVELNGKGVELNGKGVELNGKGVELNGKGVELNGKGVELNEKGVELNEKGVEPNGKGVELRENGVESKEKEAEILETEVESTAKEKELNPLEERMDPCEKEGKSQEEGSEPKEKGTKLLAKGVASQKNGEESRRTDQPRNGEEESSENRMQVPGTEAASLNRETKRKEENLASKGGKVDRYYVLGQQMNIEEDLCHEFKGHRSISIHDLHNLCLNTNGTAERSRNAVSIAMCAMLNSSHGGTIYLGVADDGMVKGMGLTRYQRDHVEASVRWTLSKYTPPVNESRYCVRFVPVVSSKHAQGSFKFQEEKVDEERRGRPHHVLALSPITAGVIWTPRLCGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T644</accession>
    <name>A0A423T644_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative RNA polymerase II elongation factor ELL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009652</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ELL/occludin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002219">
        <property type="protein sequence ID" value="ROT71972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T644"/>
    <dbReference type="STRING" id="6689.A0A423T644"/>
    <dbReference type="OrthoDB" id="6284217at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031176">
        <property type="entry name" value="ELL/occludin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019464">
        <property type="entry name" value="ELL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010844">
        <property type="entry name" value="Occludin_ELL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23288">
        <property type="entry name" value="OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23288:SF17">
        <property type="entry name" value="RNA POLYMERASE II ELONGATION FACTOR ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10390">
        <property type="entry name" value="ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07303">
        <property type="entry name" value="Occludin_ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144292">
        <property type="entry name" value="occludin/ELL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51980">
        <property type="entry name" value="OCEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="OCEL" evidence="8">
        <location>
            <begin position="279"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="77"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="43800" checksum="CEB3D566D52435FD" modified="2019-05-08" version="1" fragment="single">ERIVQLLAVKNYKKEELKNRLYSDGIKEKDKRLLAGVLNSVLNSVSQVRDNVHHLSRHLWAEVREDWPFYTDAEKQAVKKNKPQNLTPPGNDSGHSPTPALPVSPASQGLKRPHEEVFDPTAKRPRWNASKFTKRKFENKLDSQAASRLEPQSDARADAKVDSRGVSNGRHHLAKDESPRVNGTISPAAAAADAAAAAAASKSALTTSPVRQSSPRHRHNGVSTRQSSGNHSPINGISNGLTNGHGNPPHRTNGHARVESSSIPSSSPDSHHGGDDGDPEYLRTYTEIVSSDQRSRYKADFNEQYQEYLRLHSYIEERTRPFSDLDERLRNETIGSEEYNTIRAQILRKYQATQQDSEYLQKKQRYNYLHEKLTYIKMLVREYDTKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7G8</accession>
    <name>A0A423T7G8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002165">
        <property type="protein sequence ID" value="ROT72387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7G8"/>
    <dbReference type="STRING" id="6689.A0A423T7G8"/>
    <dbReference type="OrthoDB" id="5775605at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4100">
        <property type="entry name" value="Zona pellucida, ZP-C domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052774">
        <property type="entry name" value="Celegans_DevNeuronal_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056953">
        <property type="entry name" value="CUT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042235">
        <property type="entry name" value="ZP-C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327">
        <property type="entry name" value="FI18240P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327:SF1">
        <property type="entry name" value="RE15579P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25057">
        <property type="entry name" value="CUT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00241">
        <property type="entry name" value="ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="ZP" evidence="2">
        <location>
            <begin position="83"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="49794" checksum="D026A45F8A3A25BE" modified="2019-05-08" version="1">MSSNFKTEVLPFFFSFPGRGKRLLSMEAGGSIGGILGGGSTVAGGSDSTIKPIVAAAGSTPATANQGGDNCDPTGVCYDVSVHCKDTRIVVEVMTNRNFNGRIYALGRSKTCNIQVIQSNKFRLDLSMAGQDCNTQSANGVYTNTVVIQHHSVVMTKTDKIYKVRCTYDMSSKNISFGMMPIRDPDMIPITSAPEAPPPRIRILDAEAREVETVRIGDRLAFRIEIPEETPYGIFARSCVAMGKDSSSTFQIIDDEGCPVEPSIFPQFIRDGTALQSVYEAFRFTESYGVIFQCNVKYCLGPCEPARCQVGREQLESWGRKRRGVNNPRDGRGHVQETTKEEAIAAAERKSSGASEMSISQEILVLDLGDDQSPQYREQSELEANNNYYTNSELPNTYNYEAADVTLFETCPTRSSVLALAVTCAILLLIYVLTVFYFVMRKWFRPSKNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7X9</accession>
    <name>A0A423T7X9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002138">
        <property type="protein sequence ID" value="ROT72551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7X9"/>
    <dbReference type="STRING" id="6689.A0A423T7X9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="45213" checksum="240530C1EA915AF7" modified="2019-05-08" version="1">MRDGSALMRYDPLPSPPLLTPSSVSPPSPSPPITPPSVNPPSPSPFLHPLLRSPPPPSPCPSFTPSPSVFTLAPPPSLLHPSPSVHPSPQSSHHPSPSPPITPSPSFLHPLQSSQSSHHPPQSSHQATVLHHPLPQSSHHSVHPLPSPSSLPLLSVPFTIPSITLPLHLPPPLIIPFISPPLPPLPPSIIPPSPSSPITLPVTPVSFTFLPSPSFLITHSSSSPLIPLPPHSSITPPSPHLPHYPPLSPPPTSTPHPLGGIRSFTPPLSLTPLSPPPSFTPLHYPPHLLPSPPLHHHHPPFSPPHLLTTTSPPSLIPSLPSSPPPLPGPPFHPLHPLPPSSPPSITPRPPFSPPHSLPPITTTTLPFSPPHPPPFPHLLHYPLPPLLTLFYPLNPHPTPPYPPYPPLTPSVECVLSPNRSAAITRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THR0</accession>
    <name>A0A423THR0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multiple inositol polyphosphate phosphatase 1</fullName>
            <ecNumber evidence="4">3.1.3.62</ecNumber>
            <ecNumber evidence="3">3.1.3.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2,3-bisphosphoglycerate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_005467</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27381"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58248"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="3.1.3.80"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:27382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. MINPP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.62" evidence="4"/>
    <dbReference type="EC" id="3.1.3.80" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001705">
        <property type="protein sequence ID" value="ROT75981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THR0"/>
    <dbReference type="STRING" id="6689.A0A423THR0"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034417">
        <property type="term" value="F:bisphosphoglycerate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052745">
        <property type="term" value="F:inositol phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF8">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019362622" description="Multiple inositol polyphosphate phosphatase 1" evidence="17">
        <location>
            <begin position="27"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="62"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="411"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT75981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="479" mass="54638" checksum="928C62649C0A2BEA" modified="2019-05-08" version="1">MPRRRHGAWACLALLCCGSLLRAAAAYCYSDEQKVADMLSSKSPYAKLRGNMTKKDLVPESCHPVQLWHLVRHGSRYPSEKAIQDFVNILPELRARIVNVCKGCGKLCSSDKKLISYWQSNLNESIAQTLAPEGAYQQEEISSKFLNLFPEILPDTFATEDYKFRYTATQRTRESALAYARGAFGSHAENIHMPEPTDPDPLLQFDKVCSKYVAEVELNDAAMREERLFQIGSQMERVVSRVGERAGVKFTSVEVGIMYEACRYYTAWDPETPSAWCGVFTKSDLKVLEYWQDLKYYYKSGYGHRINYEQACRLVQDLVRTFRRRVEKGEGPRGVFYFTHLDAYLKLMARLGMFWDNTTLTHEDIKAKRLWRTSIVGPFSANVAFLLSRCDDDRWFVSMAVNERRAKLPGCRGEKSCTWEEFMALLGQYESCDFDAICENDPPVVQEEEGGFDGSAGTPSTLLLVAVLQPLLRLLSRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIB0</accession>
    <name>A0A423TIB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIB0"/>
    <dbReference type="OrthoDB" id="6334967at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="264" mass="28141" checksum="DA37721603B80B2F" modified="2019-05-08" version="1">MSAGSSGRSVLPEGRSGEVRSRHRTVKKMRLFGFLPVFFAAAVLSGVHGGREKRYLFINPEAPITLGFLLNMPVSLALPTLASVNGRSLQFLTPAEGEEIPDDLLWEPAYEEQLGRLSAYFTHLENKWANSGVDINLDNLSLGSNKKTPAPSMNQMQTVTPTLPQIPGQTHPGMMMGGNQMLGRNMMMSPQQPKPPVAPVMNGSAIPGTMMPGMVPTAMIPSGGSGMAMGMASQGMNSMPVMMGMMTPQPPVTGPVSMTNNLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLH9</accession>
    <name>A0A423TLH9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001541">
        <property type="protein sequence ID" value="ROT77298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLH9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="482" mass="52582" checksum="CD76805827D448CD" modified="2019-05-08" version="1">MGVWARRISWMPSPSTPRSAKRVLRPGLRRRPHSGLGSVFLRASGRRRRRGRDAAPNPQPPRTSAGPSPGGLRATDLRKPACASTNGFRAARQLGGHSQAPRETEFEFEAEARPQVWRRRWWDHLRHSPRTSLTAAAHGLMDAATGHHHQRRPENTCATRGTTGAGAAPTRPAREESCESSESREGGVEGPPGSSASPPRALPFRAENKEVSTRRGAWLTNRRQGDSRRSGAKESERGRAGGVGRAWARRQVLEHTQLVFVLTEQLQCLWIPASYSAVGAVLGPRGEPRLRLFAKGNQTQVWPFEALRSDKCWPNAREKVAMAAAASMSAPVDCLGRVPRHGATKGKPPPSLLLRHRNLAPAHRGTHELTKFEPQARILFEIDRAGGNTPPGPEWTRGRRELRPRGNTSCSRCCHTATASQISPSRHNTEATAATFSHNPAAKGGEIERVFTAASPRAPLVAVTYDTPGAMNGLVAERDPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPF9</accession>
    <name>A0A423TPF9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001398">
        <property type="protein sequence ID" value="ROT78344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPF9"/>
    <dbReference type="STRING" id="6689.A0A423TPF9"/>
    <dbReference type="OrthoDB" id="16729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28360">
        <property type="entry name" value="DYNACTIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28360:SF1">
        <property type="entry name" value="DYNACTIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19668" checksum="5619860B68D77D0D" modified="2019-05-08" version="1">MATEPESLDILEDRVKRLEEKIFGPLPKDAEYPEVVSTLASLGGQLGSALGTRDRMMMVMKRLEELERYLDPAYGESFELSDNVKLDLVLTREEQLRNQHQQLNTLHSLKHVLDSQHISDTPNLSDELIQIANKHSQDEEAATAQSMQIKNMLDQYNAIVSFNMKKALLDVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TR63</accession>
    <name>A0A423TR63_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TR63"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="46118" checksum="C5231FB53574CE09" modified="2019-05-08" version="1">MQSCCASAFTTSLLLFPLWKERHMSRECPFPRGQEGRVPNFTGDFTRGNPHTLHHSPDRAGPNNSSSDYPSSRDVQSWHSVLMGRLFSASSTLGLSKILQGVSGEPFHPAAEVTLSFTISPDLVLLHRTIVADLSFHGDVLLGTDFLRRQDFTLQSEAQSPHGLLILGGCELSLLYTDAHSLQISLGTRLGTVTPLGEVYSVPHSTSHHVQPQSTFRETAARNHVPPVRTGPEDGQNKNYTAHRSTGIAAAGRDRCPISSGCTVPQGLSSLSTSALTEPRSPLQAGEESPFITASAVTEPKHFAESFLSPDGAIEPEMEWDDFSASLWGNSEEWDIEDAFLPPSVAVATCEAVTDDDDPGPDDPDVPDLDAEDSVGPSQDPDVEDVDADADPADPAPDTDVEDVDADGPIADVRADFTGGPDDDVTPCAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRE3</accession>
    <name>A0A423TRE3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_002244</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001301">
        <property type="protein sequence ID" value="ROT79028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRE3"/>
    <dbReference type="STRING" id="6689.A0A423TRE3"/>
    <dbReference type="OrthoDB" id="6380665at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="7">
        <location>
            <begin position="126"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase zinc-binding" evidence="8">
        <location>
            <begin position="344"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="534" mass="60747" checksum="4277E9F02DA00442" modified="2019-05-08" version="1">MGCSSAASLMVRNAGCTSEADHARHLRALFGRLQAAGVVINPGKCQFAVASLSFLGHTVTTQGITPAQEVIAIRKFPRPATEKQLRKFLGMFNFYRRFVPGCAQLLKPLHALVTPNRASRNTRIEWTSPTKEAFQACKEALATATLLNHPLPEASLSKAVDASDTAIGAVLQQRQGKQWQPLAFFSQTLSPCQSRYCAFRRELLAAYSAVRHFQPSVEAKEFHILTDHKPLTFALHSRTPRQYPREERHLDFISQFTTDISHIRGSDNEAADALSRVTISAATLADDAVDYHLVSREQRQDTSLTPLLEGQTSLYLERVKIPNSCDDLLCNVSLGYPRSYILPSLHRRFFDAYHQHHGIRATQHLIRSKVVWPAINKDVRQWCRSCLECQRNKIHRHTKFPLQTFPIPDSRFQHIHIDIVGPLPMDDGYSYILTMIDRFTRSYAHPRHHRSDSRQDLQYLDFPLRQPGHCHYSPRQPGHCHYSPRRPVRVRTLAPPTDPARVQKNQDYRLPPLCQRHGRATPPPYEAGLNIILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVD2</accession>
    <name>A0A423TVD2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative urea transporter 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000857</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>urea(in) = urea(out)</text>
            <dbReference type="Rhea" id="RHEA:32799"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the urea transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001123">
        <property type="protein sequence ID" value="ROT80407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVD2"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004937">
        <property type="entry name" value="Urea_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10464">
        <property type="entry name" value="UREA TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10464:SF4">
        <property type="entry name" value="UREA TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03253">
        <property type="entry name" value="UT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT80407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="361" mass="38545" checksum="9BC71AE093F283F8" modified="2019-05-08" version="1">MFVSSHKLRVSFLITKDCEGSQVAFANNPITGFLIMAGMFVGNINVFWACLLAGVVGVAFSKVLNQPENLISDGVVVFNGILVGCISVAVFPPLSGHQIDSLFWLYVTIAVVITSYVDKGLNALMAASKLPALSIPFNFSAAIMLLSMRSAANLQGAQLPGVDGANGTAEVNVTQEIEWGKVFEGTLLASGQIYGVGTVDSSILVWLGFFLFSPLLTVFFYMGSVIGTMIGLLVSTAPYTDVYLGLWGYNAMLSAGGLSYFLVPLPGVFVGAIVAASLAGAVQAATVHIFSATAVPVFSYPFNVATLLLLAISTSDDPPFVWVGNKTFPEQHLVRYFSEEKRLQNERSLPETEEPLQTIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZG5</accession>
    <name>A0A423TZG5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000910">
        <property type="protein sequence ID" value="ROT81850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZG5"/>
    <dbReference type="STRING" id="6689.A0A423TZG5"/>
    <dbReference type="OrthoDB" id="6393648at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT81850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="20856" checksum="57000FA68E545B31" modified="2019-05-08" version="1">MASPRTQQKTLLDLARAGDAEALQAALASLAPRATKDFFAEKPLHVAAEEGHEEIVKMLILGGVDVNGKNEKGSTPLHFAAQEGHEAAAEELIVKGADVNAKDEDGYTPLHLAAFNGHRAMVEMLIGKGAEPNAKGNGGSTPLHFAAQEGHEAAAEELIVKGADVNAKDKNVADGGKPNPRMVKPLDSHGYQESAVAATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZI1</accession>
    <name>A0A423TZI1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000909">
        <property type="protein sequence ID" value="ROT81866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZI1"/>
    <dbReference type="STRING" id="6689.A0A423TZI1"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="73"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="251" mass="27737" checksum="3A0658117EAD91F4" modified="2019-05-08" version="1">MNHNCQHSIEGVGSLGALRASPFNHPSSQSAHDVSQPAACLTPSTQLSCTMSSRIPAITLHNGGKMPMVGLGTYKSRDDEIRQALNVALECGYRHIDTATVYENEVEIGDVLHEWLSSGRIAREELFVVTKLPMTGNRYKDVGRFLQDSLDKLRLSYVDLYLIHSPVGMKEHSKGEFDLDTNHEEIYKAMEEQNSRVFTLISPSRRRRRTASSPEAQRHNAVRAGSPCRASDSSASFSSAPLFPAHAGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1L1</accession>
    <name>A0A423U1L1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_024212</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000796">
        <property type="protein sequence ID" value="ROT82618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1L1"/>
    <dbReference type="STRING" id="6689.A0A423U1L1"/>
    <dbReference type="OrthoDB" id="6356824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050370">
        <property type="entry name" value="HES_HEY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10985">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="82"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="334"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT82618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="368" mass="39568" checksum="9D4B56FAD8475F3F" modified="2019-05-08" version="1">MGVQQQQVVNKARAPKPVSEARKIRKPLMEKKRRERINTSLNDLARLLTDAKMVKSDGGAKANKLEKADILELTVKHLKALKTEGGDARGEDAPTEEPAVASYKEGFTNPASNAAACPAPTDARDAHTPQPSEDTPSRLAAPDAPVTPATSEGAQEPSPVQQEGAKDDSAAKDSANPERAANEAPRFTWCLPTGAVAFLIQGGLRPPPPSRPRSCILECHECRHALVCPSAPRPAAQCPPTPPPSSTPAPHTLSLSVRHARLLARALARAVQCPSPPECRRRPLRLEHEEDVASLVNLGGRGGHESRRRRVAAKDKDCVTKSLCLWDPRKRRRPICDSLSYGGIGKNRSTAPPTPPSSPPPPTRPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U230</accession>
    <name>A0A423U230_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000781">
        <property type="protein sequence ID" value="ROT82734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U230"/>
    <dbReference type="OrthoDB" id="6361206at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="28320" checksum="86266A480F870531" modified="2019-05-08" version="1">MALQGHSSYKGSETKGHNADDSGDENKDLLNRLSCIMVKTQQIFGQMKGLSSQLNDPVKKIDCVSKTLQRQFLMMQEAMVCAYDLPEYDQENSAAKLVPIARIRELVLNIKKLSVELGKPIAVLQKLVSEMQTFSEKSLIKKYRRSHLECVRDFAEQLFSITDKFVKPVNRLDSLIAKFQGLTDNMQIYIIAKVQDEKMGIWHAVVRSLLKTSDILLRLKQLVETLSYKVNWFACKCQAFILLLKVGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U272</accession>
    <name>A0A423U272_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_024047</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000775">
        <property type="protein sequence ID" value="ROT82803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U272"/>
    <dbReference type="STRING" id="6689.A0A423U272"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008504">
        <property type="term" value="F:monoamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015378">
        <property type="term" value="F:sodium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090493">
        <property type="term" value="P:catecholamine uptake"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006836">
        <property type="term" value="P:neurotransmitter transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF320">
        <property type="entry name" value="SODIUM-DEPENDENT NORADRENALINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00754">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0532">Neurotransmitter transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 16" id="KW-0769">Symport</keyword>
    <keyword evidence="5 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT82803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="203" mass="22972" checksum="B53B9F99D6877C84" modified="2019-05-08" version="1">MEHSQERVCLLLPWPPAHPRPPLAHPGAPWTPKFYRRGGRRAESWGKSMDFLALSSIGFAVDLANVWRFPFLCYRNGGGAFLFPYFLITVFGAPALLHGVGARPVQPPGTHYRMESVPLVQRSVFLAFSVGYCAVLVAYFVSFYYNVIIAWSIHFVYASFSYVLPWTSCNNTWNTDDCWDGLTSDEPKPNSTSLMSPSEEYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U302</accession>
    <name>A0A423U302_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative nascent polypeptide-associated complex subunit alpha, muscle-specific form isoform X7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023743</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000742">
        <property type="protein sequence ID" value="ROT83076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U302"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="741" mass="79066" checksum="55BC513E2797610F" modified="2019-05-08" version="1">MVHLSHLVIYMGIVEGEPDQSRSESHKEAIELGSRLIHVNYDCWSSHVAPGRVWVLNFTSLTWHHLEAPRTDARDAAAPPESSQAGVDPPLARAASTPPAAPAPPEDATPKGVPVASESAPLALCSWSKGIIVLYALNGSATTWMFSVKTGKWLETTHSKFPPAAAALEASWCGARHDAIWFLTSKRQKAAGPARSSSASVQGTSQTLWKLDHLGKWSRLEVTQAKGESHLESPATVLQSWTDARGNLFLLQEHEAPESKVSVVRFDPSSGEKTLTGLKGGARDGAWIPGSSGELYALFPRDGASWVATYDYYSGDVISTEKAAMPMASESLFVKVDGVIHTTIPACRHLPPMPPHLQEPSPPDMRFSHISLSRVCAPGEMDFPAGRPSQGVIQGPRKADVLSNVQAPPKNRYVSDTRAAAPAQSSSNHLDVEGTRDGAATTTLQDHGGEPGVSRTTGKSADIIMVRDDQEVSADVTTAPLAGSQDLRRRGGEGGGWRGGLDVPSDNGRLSPQMRTWPVGPHQMNRSHTHDSIIFFSLSLSIFALVGIVVFVRRCVRLYRCPVVLTPLSLPFQVPPSRGLGDAPEDRGKPPSPLPVLYSIVPDDPAYETSATESPCISHHALYDSSPYADLPNPSTPNHAAPNYMTPGAMTPGTMTPGAMTPNAMTPSTMTPNAMTPHAMTPNAATPLPSSPNAGGRHPTIASPGEFPKDALTYAITHSASDAINIATNNAFNTYISTTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4Q6</accession>
    <name>A0A423U4Q6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative tachykinin-like peptides receptor 86C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000659">
        <property type="protein sequence ID" value="ROT83652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4Q6"/>
    <dbReference type="STRING" id="6689.A0A423U4Q6"/>
    <dbReference type="OrthoDB" id="5975505at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032870">
        <property type="term" value="P:cellular response to hormone stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241">
        <property type="entry name" value="NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24241:SF76">
        <property type="entry name" value="NEUROPEPTIDE SIFAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="10">
        <location>
            <begin position="117"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="296"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="337" mass="36632" checksum="C2965A030456164D" modified="2019-05-08" version="1">MYIFLSSPLPPPISFYPPFLSLPSPSPPIFFPLPPHFPPHLSLTFPPHSLPSPPSSPISPPLLSHLPSIPSSPSFPILPHLPSPPPPFASLISPNFPISPRPQVANRNIPGDTRDAAIHEMQQRSKVKVIKMLVVVVIIFSLSWLPLYTIFARIKLGDELGEDEGAVLAIIAPISQWLGSSNSCINPILYAFFNKKYRNGFLAIMKSRSCCGTLRYDTYSQSTMRRSCYPAYRSTIRPEAGGAMELARNTHRASAGFVYTLDGRPNPPRSRYQAGGRQRSLANGFSTALSLADSLTTTETSIAQPSSRSSSVVGSADAADSEDKKSTFTNGKLDGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5C3</accession>
    <name>A0A423U5C3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_022927</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000628">
        <property type="protein sequence ID" value="ROT83889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5C3"/>
    <dbReference type="STRING" id="6689.A0A423U5C3"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="13">
        <location>
            <begin position="173"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT83889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="231" mass="26353" checksum="F459A4D3DDD885EB" modified="2019-05-08" version="1">MEGNKYSFGYSGLEGAAEQYNSQNRVTMVISRSFILTLGTGMFCGFFSFYLLNTTVTLHPRYIEGISPPHSVENHAHNHEDLENAAGPLGSVSMHSIHEAHHAGESVEAEQLKGKVRVLCWVMTNPKNHEKKARHIKATWARRYKELGAVALEVGEGRDHLWEKTKAAFVYVYNNHYKDADWFLKADDDTYVIVENLRYMLSPYDADDPMWFGCRFKKYVKQGYMSGGSLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U647</accession>
    <name>A0A423U647_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022634</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000585">
        <property type="protein sequence ID" value="ROT84184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U647"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="19043" checksum="6A2401286DA9410D" modified="2019-05-08" version="1">MRLVEVEVGSRRFEASVVLQLLPSPSFVLNLKSPEHSYFVKGFAGSRESVTQMASVEFGQNRLRYGVRLQMSTPKLDDRLVWSPSAFFLMPESGEAEVMRAFLSLKENAYGFASEFSFSTLGAVADYVNLQITGGFSQTTDSHLPLSANSELSARRPIGSCRSVTGQCAFPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7X9</accession>
    <name>A0A423U7X9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000490">
        <property type="protein sequence ID" value="ROT84830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7X9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="515" mass="57130" checksum="3C4FA0D2ED954BF5" modified="2019-05-08" version="1">MFLQLPSFSLSSFLLFSPPPSSHTLNFLPSSPLSSPSIFTSLPFPSPPFYSPPLSLPSILIPSPLPDAQREQGVGESLCYGVAVVECLPLQTKLSLLSLFPLLFSSNVSLAFSSLMLLSSHPLSSLLSHLSLPSLSLLPSLLPPSLSPPWPPPSFPLLSLPYSPSPLSLSPSPSPSALYASLTLTSPSHPLSSLLTSTSSSSSFFGQQQAINNWQCCNEEFCVGCPVRGPFHFLSSPSLPPLSSPFLSSLLNSFTLLPLPSFGFSLLFRFSLSSSIFSHLLRSHHPVSPSPFYLLIYPLPTCPFYSFVRNKRFSFSLFALPFSPFASFSHPVFLLSLLLSLYPLPFSSFVRNRRFLLFFSIFSPLLRSLILFLSSPFLSPFIPPPFLLLREKQTLLLLFLFSLLCLFLPILFLSSPFLSPFIPLPFSSFTLLLFFSIFSPLLRSLILFSSSPFLSPFIPLPFSSFVRNRRFSSSSLFSLLCFVLSSCFPPLPFYPPPFLLLREKQICVRSMTYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8Q6</accession>
    <name>A0A423U8Q6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000450">
        <property type="protein sequence ID" value="ROT85051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8Q6"/>
    <dbReference type="OrthoDB" id="6338895at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="235" mass="26707" checksum="7739AA19A9B3F177" modified="2019-05-08" version="1">MFPTPLTDSRPFQRGGFFLEAGALDGYYQSNTFFLERDLGWTGLLVEPNPVFFESLLTRHRRAWATDLCLGTKPYPVKTEFWVHTGADPWQSLIAASRSGLLKEHLENYQNGGLDSGSVVEVNCVPAISILSALNVTQIDLFSLDIENAEVPVLQWFPFDRVHVEVLVVEHWTSGDPEDSQAFVRLVESKGFSFYRRDNHDYFFLHQHPRWVLARPGDEGAVDNLAPYEPLIGHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBI4</accession>
    <name>A0A423UBI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000045">
        <property type="protein sequence ID" value="ROT86023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBI4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018982445" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT86023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="117" mass="13153" checksum="462A612C0308D47B" modified="2019-05-08" version="1">MIRAVLATLLLAAAVAEAQYGYAKPCPPEVRHVTKTQSVPQYVTVTRYQTQTQYHTAYTTQYVTETQAVPHYVTQTQAVPHYVTETVPQYVTTTVQQKEYVTVDQYCKPSGGYGYHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQC7</accession>
    <name>A0A3R7LQC7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004086">
        <property type="protein sequence ID" value="ROT61604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQC7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="40938" checksum="D1FC8EE14BD309BA" modified="2019-04-10" version="1">MLGKTAISTNVVSRQTFSPPPLPQRSPPPQPPPQPSPPPSHPLPRNFPPPQPSSLHKTSPPRANVFAPPPPPPTPPTTFPSAVTVPHPPPPPPPTNVPLRRKCFSPQPPTPSHKRSPPPQPSPHPPPHPSQTFPSAAQRFRRPAPHLPQHFPVRRQTVSPPPPPHPLPQTCPPPKASPAHQTFPSAAKTFSASPQPANSPHPLPTPSTNVPSAAKYPHTRPPPQTFPPPPATRLAPPPSHPSRKRSLRPPPPPSHKRFPSTGLPLPPPPPTNVPLHRNVFAPPTPPPSHKRSPPPQNVSAPAPPAPGGRGGGAPGGADHTRKTKPFDNRPLMGKQSGERRAAPRRRPWRRAPKAGDRKMGKRTRPEDVKRVSCGSGESFSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LS01</accession>
    <name>A0A3R7LS01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019329</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003546">
        <property type="protein sequence ID" value="ROT62812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LS01"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="496" mass="53459" checksum="1A854D7174E79B74" modified="2019-04-10" version="1">MHIAYTNAIRLHERAIRRRFTNGEQFHERAIRYTNGGSNPPPTRTGSNPPPPTGSNPPRFHERGAIRLHERGAIRRRFHEREQSAAASTQRGAIRYTTGSNPPRLNGGQSAAFTNGAMGSNPPLRGASATRRGAIRPRFHEREHMPRFHERGAIRRASTNGEQSATRTGSNPPPLQIALHEREQSAAASTNGEHPPTNGEQSPRFHERNPGAIRLHERGAIRRRFHTQSATRTGAIRRRSTNGSNGPIRRPSTNWSNPPNERGAIAAASTNGSNPPYTNGEQSAATTNGEPPSPPTRSGSNPPPLHERGAIRLHERGAIRPPTRTGSNPSPSNGSNLAPPRTGSNPSPFNERGAIRLHERGASDGEQSAAATRTGSNPPPLPRTGSNRAYHAGSNPPHEREQSAASTNGEQSPTRTGSNPPPLPNGEAIRLHERGATRTGSNPPTRTAYTNGEQSVAAYTNGEQSAAASTNGEIIITRRRLCPPAPHAMKYLTRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVV2</accession>
    <name>A0A3R7LVV2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transcriptional repressor NF-X1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004646">
        <property type="protein sequence ID" value="ROT60658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVV2"/>
    <dbReference type="OrthoDB" id="6382057at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21698">
        <property type="entry name" value="PROTEIN (PUTATIVE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21698:SF4">
        <property type="entry name" value="PROTEIN (PUTATIVE)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69349">
        <property type="entry name" value="Phage fibre proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018560371" evidence="1">
        <location>
            <begin position="21"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="525" mass="56645" checksum="A5E0B6D4173D3E1C" modified="2019-04-10" version="1">MKTVAFLMLLTAGIPTSAVSRSSFFLRHTENHRCGSPLAVAQVSSLTGCAALCNQDSACVGFSLEVPGSRRRSCEMATTASDACGNIDNTCGNNFNNACGNNFNSACGNNFNNACGNLYNTCGNNFNNTCGHNFNHAFDNLYNTCGNNFNNTCGNNFNNACGNNFNNACGNNFNNTCGNNFNTCGNNFNNTCGHNFNHTCGHNFNYACDNLYNTCGNNFNHTCGNNFNHTCGNNFNTPAATTSTTCGNNFNHTCGNNFNTCGNNFNYACDNNFNYACDNLYNTCGNNFNYACDNLYNTCGNKLQHTCGNNFNYACDNLYNTCGNNFNTPAATTSTTPVTTSTTPAATTQPHLQQLNYACDNLYNTCGNNFNTPAATTSTTCGNNFNYACDNLYNTCGNNFNHTCGNNFNTPVTTSQHLRQQLQPHLRQQLQLRLACGNNFNNACGNNFNNTCGNNFNNACGNNFNNACGNNFNNACGNNFNNACGNNFNNTCGNNFNNACGNNFNNTCGNNFNNTCGNNSICGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXU3</accession>
    <name>A0A3R7LXU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acylglycerol kinase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002809">
        <property type="protein sequence ID" value="ROT67446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXU3"/>
    <dbReference type="OrthoDB" id="10449553at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="13795" checksum="E0B4C70BD7F56585" modified="2019-04-10" version="1">MWGCQKNNGHDISDLSVVTRNTPESLDIPNYALALKTGPTNVGSFAFIQEGWSREWNKSNSYDAESIIGEITLTPTGNTKTKEGEDRELSIDSETFEVRPMKIKPRPEAVTVFAPLTPPFTAHVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYT7</accession>
    <name>A0A3R7LYT7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003582">
        <property type="protein sequence ID" value="ROT62629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYT7"/>
    <dbReference type="STRING" id="6689.A0A3R7LYT7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018569731" evidence="2">
        <location>
            <begin position="28"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="48830" checksum="91A2CC7A6FCE6409" modified="2019-04-10" version="1">MTQPRLCGVLAALTCLLSLTPTSKVIGERCWEAQPECIILGRFWYSQELSIASAFPSQDAGLSAEEFWGCNGVSVNLTCRESHQYFSYSLDNMKVRYESVSMECVNGTWVTTWPSNALDLGVLPGCSRVPLCMGEFYAKSSVNVFGKDIVIFGGPERTHLVNTSLPEKKYSVIMTVEGEKCRFPFSYNRLTYDSCSVFNGTSSCGKLFHADDTSLGECEDAKCDHLCGGAMTIGPDDLAGNNGTLRCVKNGFHLGDTKLLEGKKYEVSCTSVETTATTTTTTTTVSVTNSTTVVSTTASANTTAVPSTTVTPTATTSVPGENATLVTTSGTLLTTAAGGVVTSNTDSTTEATLSTNSTVDTTLAPNSTVDPTLASGNTTDFTLAPGNTTDTTSAPGNTTYTTSAPGNTTDTTLAPDNSTDTTLAPGNTTDFTLATDNTTDTIIAPDNSTNGEYILSSSLIFFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M099</accession>
    <name>A0A3R7M099_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01002565">
        <property type="protein sequence ID" value="ROT69416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M099"/>
    <dbReference type="STRING" id="6689.A0A3R7M099"/>
    <dbReference type="OrthoDB" id="6108687at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048666">
        <property type="term" value="P:neuron development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF562">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="133"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="238"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="411"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="512" mass="58338" checksum="81E82AD3299160EC" modified="2019-04-10" version="1" fragment="single">KIPVAFKRSTSYFSAPSNRAKNRYRNNILYDDTRVVLQGKEGGDYINASFVQGYNKSRGYIATQGPKDCNDSTIEDFWRMIWEQHCNTIVMLARLIEGGKVKVAQYWPDVKKNQVTQYQFIAWPDHDVPQAPFTFSLMTLEIRRQKVTGPLLVHCSAGIGRTGTLLLVLVLLDQLDQDGYIDAPLAVGSLRKGRPLLVENQMQYRFAHHLLLEILYSDVTNYPVSEFVEMLPQLDKEIRIQYEKLKGTERNLSFRWALKPAHAKLNRNPHILPVDGRQVFLQMVNGQAESQYINAVRLNGVTQRDATVVMEHPQPDTLPQAWRMIYEKKVSAWVLLNTYGEDEDFPSVIPQAEMDLGFITLTLEGEESKDFCRVSQVTLAPVRSRFAVSHSVQVLQLCGWRRGSELPSSTEHLLALLQDVHAIRKKSPSSPVVYTCGDGCTASGLAAALDVILTRIDLLRDVDIYRAVQAVLYERPQFIGSLEQYKYLFKATAEMIKRKPREKEEEEAMINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1C2</accession>
    <name>A0A3R7M1C2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017516</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003238">
        <property type="protein sequence ID" value="ROT64543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051697">
        <property type="entry name" value="Patched_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796:SF130">
        <property type="entry name" value="PATCHED DOMAIN-CONTAINING PROTEIN 3-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796">
        <property type="entry name" value="PATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="798"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1064"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1216"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1310"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="4">
        <location>
            <begin position="353"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1175"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1177"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1190"/>
            <end position="1199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1374" mass="154199" checksum="66B40F27D61AFCCF" modified="2019-04-10" version="1">MSGSMNKVTPDRDPDVPPAAGTQELGVLGRISGVIIGLLEHAFYCYGKAISRAPFVFIFLCLAFTGFCAIGITKFTTEERPFKLWTPTDSDFLEITDWKEANFPSDLRLNMAIFEAENVLEKRVILEMLRVHDVVVGTAVGDVSWEKVCAKVPTLTAALFGRRKRDVGDEAYPGLREEPRVVRQTDDYEEEELDWSLILSREGYCDFQANMEQSCLENSLLEVFGYDRRDIESLSQTEIIEEINYADVSAVFGFPLNATKFLGGVERDSSGLIVRARTAMHMWFTRVNRTAIALGEYLDDGGSGSQVDLMNFNWEQEFIKNVLNETDRPRDISFYLGASSSFGTISSSNIEGDLQFLTAGFGIVFLYVVVMLGKFNLVEQRPVLSLLGLSCVGLAVGVSYGLCSAFGVPYGPVNNILPFLLLGLGIDDMFVIMQSWNNLSPQEQTKDLHERIGSALRHAGVSITVTSVTDFVAFAIGSTTVLPALRSFCLYAAIGIAAIYFFQSTFFVACLSLDQRRLEDSRHGFLWCWKIKNWTPNECSQRDLCQTFFTEVYAKYLFKLPVKIVVIVVTAAVVAVSGWGLSNLRQEFDPIWFLPQDSYLYEFFMKQKYYYPSSGEEGTIYFGNVSLLAEMPKIEELVKQLNENEYVAEVDSWFLAYKKYWGKQGISVPNPDQTEDGFLDQLSRFLHSPSGSPYRSRNFRFSGELICYEKAPPVTASSINYKHRMLQSSREKSKAMEDVKAIVRNANFTGYVRPWSRAYAGWETDQVIEEELYRNMGLALLVVFVVTLLLIASLPTSLMVLLCVFLTLIDVGALMHWWGLTIDTVSCIDLVLAIGLCVDYAAHVGHTFMTHAGTRDERARATVGRIGPAVLNGGFSTFLSFVFLSNSSSHVFLTFFKSRNFTRAAPPVCPRPRTGDIPSVASSARGKDLGCLPASHLPRFCQGDFFKSSMETAILPASPRLQFPHREKLSNSTILPFEIDSPPAYDTRERYVKFDFLANWSADHELPFRERIRQLFPGNWTGERQPGRRIFDSPMVNETALLPVTEPDGGRPSLPFQMSLHLEVIWSVAFIVLIVGACVGNVLVIMIILGISDPRCLIPPLLGLVRKEPSPPPELPQPVRVPAGEERPRYVPAGTQPLAVHEIEAHREQVPSSDPKFLRGLERLSFESVLAEAKKEREKRKRKRQSAMKCHAEGRREKRRENLSCNRRMKTTTNYFLLNLSGADLSMAIFNCTFNFFYMLKSHGHSGRPTACAVHSPRLPGGFGLHLAVISFDRSVVWACSGRKARRWLWYVRVPQHESLGLPPPPLRTWLVSALLAAPILPYATTIYSSMWPRSPRLSRKGMSVGVLTIPDACASQLVQLLFDRQLRHGVLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M274</accession>
    <name>A0A3R7M274_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative glycosaminoglycan xylosylkinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_010798</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAM20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002372">
        <property type="protein sequence ID" value="ROT70902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M274"/>
    <dbReference type="STRING" id="6689.A0A3R7M274"/>
    <dbReference type="OrthoDB" id="8583677at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024869">
        <property type="entry name" value="FAM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009581">
        <property type="entry name" value="FAM20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12450">
        <property type="entry name" value="DENTIN MATRIX PROTEIN 4 PROTEIN FAM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12450:SF14">
        <property type="entry name" value="GLYCOSAMINOGLYCAN XYLOSYLKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06702">
        <property type="entry name" value="Fam20C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="FAM20 C-terminal" evidence="7">
        <location>
            <begin position="228"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT70902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="317" mass="33644" checksum="ED0EE1EE6285EE9E" modified="2019-04-10" version="1">MTDVPLTASACHTGADTGVQGMRTLLQVPFVLPSGAPTREPAAWALTSEFISWLGRVVHLWRLDQFRSNLSRTCAELQYAPNAFETMAVTRNVMVCLFVAAFVSVNLFMANLTTGNAAQDRRFPQDEALASTMSSDGAAPTRVLAAEGLGREAQARLDPKGSRGRALGLGGRVGHARVAGSCPRPGLGDVLDALSAAPITAADVGRGGTQLKLFLTLKGGQAAVFKPESFGDAGVDFMDILAPVLQCCRLRRSTHARLVLLSGGGLSRALRELLRLDPLAPVLADAHLRALDRRLAHVLAALSACSEREGGWHNVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M443</accession>
    <name>A0A3R7M443_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M443"/>
    <dbReference type="OrthoDB" id="6344476at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018595408" evidence="2">
        <location>
            <begin position="30"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="155" mass="17862" checksum="A4790FEA49898BD9" modified="2019-04-10" version="1">MLPDYSILPTLFGKMYFLVVAAVLAMVAAAPQNGDQLDHQARPYYRPLATLRNHRQDLGDGNFNYEFLTENGINVGARGTPGYRGQRVLTDPLSFYHSYPLADGSYAEVRYVADELGYRADSRLIPSHRYRFDRRLNPFRLAEVQRRLRGFRPVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5J9</accession>
    <name>A0A3R7M5J9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_009023</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002132">
        <property type="protein sequence ID" value="ROT72582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5J9"/>
    <dbReference type="OrthoDB" id="5956066at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="64005" checksum="D5348A4B94F00588" modified="2019-04-10" version="1">MTWPEENNIHFELEAQVWKMEMKFNSPWMPFQEVIFEMSLQTESEDGKFSAKLEWDNHNFVMTAILSPMRSQFNAKFQRENSDIFGATFEYNFGEEMVNECRVKVGVSSGMDIDSYGFHFRQEALEGGHHISLSGDSAENNFYAEDEYRGAVELMLPAQTVHWNTSALCGSGDFDLQSRFTWNDLDQEVPAVNLIVKYDDKSHFGQEEHHIMAVFSHPEIKNIVLQGNITQSEDTTLSALVELIDENVPERNVILAVDIHPYTENRTRDINATITQSFSGFAVNMDAQITDSNFHDGIYEFKYWSLTKETWENLHVSTRVEPSMDGFDFEARVKAPKGNWGYTYRGNAFSNDHEAAVTIMGISDRYGDFWEIETTVSKHLPEFTVHLDIGQENEEAYEKGRLRIGLHNPLEIGAALDHRKFGEWRQDGAIGLRLKTEDILQFVLEFDPSLDYQNEHFLVDLVSPADQIFSSWGRDLEYTTSAFAKWFMEESPSMYQVLVNNPTVVRVWNAEMHHFQEFVSEMNGVITDIHNDGQQIWNTVIQPSLNAVRETFNEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5S3</accession>
    <name>A0A3R7M5S3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD-dependent oxidoreductase domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_008826</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002113">
        <property type="protein sequence ID" value="ROT72781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5S3"/>
    <dbReference type="STRING" id="6689.A0A3R7M5S3"/>
    <dbReference type="OrthoDB" id="424974at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.9.10:FF:000026">
        <property type="entry name" value="FAD-dependent oxidoreductase domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847:SF287">
        <property type="entry name" value="FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13847">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="5">
        <location>
            <begin position="117"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="5">
        <location>
            <begin position="223"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00039785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="47734" checksum="E38DA418F6CCE6FB" modified="2019-04-10" version="1">MYALSRSANRLVRGCRTRGKQFNLRSWRYIWPETRKCLSTSGSKFSDWEDKPGGGPYRSHEDNPVRRTFNILSDDVKGYFGLSGKTQPSDPSDAPKNTEEKNHKSKDAEKIWPSFCDVLVIGGGAVGSSVAYHLKERALRGLNVVVVEEDSTYKRASTVLSVGGIRQQFSVPENIQLSSRYGNETSCGGHLNSLAGGGIGCLLMYEWPYFFTIRFLQITLPDGEKRNIRFSICVVAAGAWSGEVGRLVGIGKGTGIMGVPIPVEPRKRYVYCVHAPDGPGLDSPLLIDPNGTYFRREGLGGLYLCGQSPTDECEPSIENLDVDYDFFESNVWPTIANRVPSFENLKLQSSWAGYYDYNTFDQNGIIGLHPIFTNMFIATGFSGHGIQQAAGVGRAVMESILHGEYQTINLERFGFERVLTNEPLYEQNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7X3</accession>
    <name>A0A3R7M7X3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_007023</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001890">
        <property type="protein sequence ID" value="ROT74472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7M7X3"/>
    <dbReference type="OrthoDB" id="6362414at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="181"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="214"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="15"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="745"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1394"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2001"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2366"/>
            <end position="2389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1115"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1858"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="456"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="500"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="556"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="637"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="814"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="942"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="997"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2001"/>
            <end position="2013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2366"/>
            <end position="2378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2412" mass="269806" checksum="1565C07D3D051A18" modified="2019-04-10" version="1">MKKFKRVFGSITNLAQDDSASRGAPPPAALSTSRRSVSGSLHGSSGSPHRGSYVSYESQSLDSYNSNLSAGQTEIDPYSKQDKNFTKLHKWAYLGDIAKLKKFIKKIPVDSQDSDGKTALHHAASQGHGDTILFLLGSKGNVEMKDNCGMTPFLRAVEKCHLPVVQMLLQRRVDTQITDFQGNTPAHLAARTGATDLLMLLLDCGCEYDDQNSLGRSPLHIACSENQPEAVEALLRHGASVNVIDKEGVTPLMVAAKIGSAPVVESLLDNGADVNPVDSSKWSAADYARFTNHNQLHQRLKSLMRDGGNSSLIPQGLLNISDEVSTEEEGAVGLTRDRDMDEDGGDSWSDNSDVASIKEKPKINLTKFLPSSDDSGDNIFSSTPEPGSLIGPPKPPRLHASVSSVASEPANENDVETTSNKEEVLGADDSWKSSSEEDEPKRVLKHVSKVEEEENVDKKKESKDEKHSEAEDSWKSSSEEDEPKKKLFPLFHGESNSQKLRRDELLDSHEPKQSESHAGNSKFLADLGLDNMEFHSSEEVSFEDEDSMLPIEGTPTKVTVSRRNSQAIGSNVGGGESLPFSESPAAVSPKRQFPKVSEDEASSNDFSDSDKQKFPLSSRSSTKAKEEGGNISPQKTSPKKSPSKRSPMKAKMIRKSSSIFDSDTDEEAASPRRPPRKKSLTPTKKKFSPSSFERSPRSQDNKNEDEDNKLGSSSVTQCVEDAKVAAIDGKEVLDALERKRVEVIAQGKLSDSSTSGGSKGSLGAGGIASSRTNSPSTVVGTLGREGTMQELEEVWEANASISPKKYYSSTSNHGSEDSPEHEKTDENVKAKAKPDMHKDETDGVPREGEIVPQQLEDQGKKDMMKTTTQLEPENTSRDVSDDDLISGGVETPLPGTHKGSHTQDLSRVSPLKMGRMPTSSEVRAAEGKGNVQSLKEKFSVSLEESVSSPRSKVTVRTPRRMSKEEQVSPVFDSPANDHASPPKRPEASISTPREPPISSTPQSRKGSRSGITRSSGLGSIVFSDEESIIPDPLITPRCIDDADDMVSVASTETEESTHINSGLKDSILTPLSSLPEANNVSQLQDLVRELRLKLEKEFGRRAAQETKISHMQQMEKQCKKHIDEQEEKMQHQQQEISSLMARIKQLEYRGKCEQDSSRLKDQSLEEAQQQCVQLQDQCVHLRAHAQQQEELVDSLMGQLETKERVNQILQSKVEELSSQTKFVSMKSCQTEETYFASQSTATNDIQPEESEKLDVASQTICSTLDAVDVEIQTEVETQENFVTKSIESVPLQQAKQIEKSSFSTQTEEILKNEVHNVRDAETQSEECRESQGISTAVQCTPETIVKSCQTQILIQSRTVQTDLTNANSHIQSKKVVKDMPCQTSALGRQAAVQTDVQEAPHPRELPDGQQETRPSISVHDITSALEPVLLNFSNDVKTLITDTFDVNQTSAFENISQCLIREIQNVGSILETSLQQASSLQCEDTQQKFTSAMDRIEDSLRSQLETTAQLLQSRERNNSGEIQEVLEKVNSSLVASFEEVRNDLHKIQRQRGSSEQDVLEKLDYSFRNLKESNDYSVKSLSDAIKTSKDYNMHAIETLKDDLMPKFAEMKRAIAANQPEDSGISESLGRDITDKLGKMERSLMSSFEKSLSTQDLSGVEHEVHRMSEELQRKISTLQQSLQSVDSGTRLDLTEVDADLKSIRESNKQVMSLLKARSSESNTNLSEALEENFLILQDHLRRLQQTLVQRINEVSQHANLAEDQKLSWLSKQITEMTTQVAGMQTGLMRMQSSLEASQNLPSVSGIIDESLISALKASNEQAVSSLKFQNQSMIQLLESLQKDVHSFIHQKPIIKDGPDVQLLKDSLHSKELELDRLSSNQEKLQEKVRFQSANLERLQQAELHHQQTIESLSRDLKEAQSTLREKDERIHEVTLKTASQNDDSSRIRQENFRLSSENGKLSALLQAEQHQRQWYEGELHGLKEAKDISEARVQELIQLLQMPRQQPPMLRTPPTGRDNDDDSLADKKKEIRKLEEEKLEAENQYKEECSRAQRLELRLRETEAELGLERNSKGELEKQLRKTKDSLAQLQQGIQEATQHQESLQDLTAQKKELEAEIRNSNDTIETLRKKIESINQEKLQLKQEVMMLKGEKLSFELIRQEKELAEQMQKRAEEQLMELQRKIPREYVPKATLLHLQAEIESKCQLELSNKLAELNQLIDQQSQQQQSQAKVKESQEQGLRNEISRLSEEIIRLRAKLSVYSEEEDTWKTRHNRLMDLYQHEVQTKHNHIHKNTQLNKPKEESVSINLREINAHLQTPFASSTFLGQLTPPSSLHLPKAPSNIDSYHYTHSDTLDRTLNKYLSSVDERPRSVRIDDKPQTRTSHVQPPPTLWRKEQVPTLDQSCEDFDLDLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7X5</accession>
    <name>A0A3R7M7X5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001785">
        <property type="protein sequence ID" value="ROT75325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7X5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018762004" evidence="2">
        <location>
            <begin position="34"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="50937" checksum="23C660F6EB2D95DD" modified="2019-04-10" version="1">MTFVCHTTASNLSSAALCLVSIVSLQLPSFSSPRSTPKIRHPSTQPTPRVPTLHNDYRRTSPYAGFTGPAVPNREPKAGIPVKWHCRRNSCPADGSPADRPPSRTALLTTPHRPAAHPPVTKISSLPAVKKTAHYPRSCPLTLLTLPSFPVYAFLSLPAQQKTSFNRTHTLVPAHSSPLSFHAVIAIRKAATPSAPASDKVSTGPRTQAPLPATQSQVKPRPPSPPATRSTGPRTQAPLPLNHSSASDKVSTGPPDASATTATPSGSTQPKVTPTPSYRNHPITAASGRTSLGNHSNVWDCWRPTYGCIVQARGRLLIRTPAHIRDKWSLPLVVSLTPDDELPSAAPHVSETIGVSHLVVSLKPEDGLPSVPSRVTVICYDSAVDIRVKPEDGLPSEILRASEASDASIRTFFFRAEAYRPLPHPRTRPRIPSTPTLDIRFFFVYVCFFLVPFADCLVPASVPSTVGTALMISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MB44</accession>
    <name>A0A3R7MB44_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FAM60A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001577">
        <property type="protein sequence ID" value="ROT77012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MB44"/>
    <dbReference type="STRING" id="6689.A0A3R7MB44"/>
    <dbReference type="OrthoDB" id="10023333at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030336">
        <property type="term" value="P:negative regulation of cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026065">
        <property type="entry name" value="FAM60A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13422">
        <property type="entry name" value="SIN3-HDAC COMPLEX-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13422:SF12">
        <property type="entry name" value="SIN3-HDAC COMPLEX-ASSOCIATED FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15396">
        <property type="entry name" value="FAM60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="36726" checksum="BADE7373A0518D33" modified="2019-04-10" version="1" fragment="single">AGQRTGRALGEKRRKYQQTRQRAGSATKHKMFSFHKPKVYRSTTGCCICKAKSSSSRFTDSKKYEDDFVECFNLKERRSGEICNACVLLVKRWKKLPKGTDRNWHHVVDARAGPGTKSLTKFKSKKLKKNPLNPDKPVKEKIKKKHRYVRKVGREGSPGALSDDVTVGDERLSEGSGPSVPGSLAPSPYPSPYPSEDDADSQDRTLLTGAAKRKKQNPSQFQLSSFVDLSYWKQEKVCCGLIFRGDCGEVLIDPRFFQPCSCRIKSLESSPAPTPASTPLASSGASDVTGSGLSSQHSLLPPLYRVCHHRSFVLYSLPTSSSSKRDQQVHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEJ3</accession>
    <name>A0A3R7MEJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Crustacyanin-A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEJ3"/>
    <dbReference type="OrthoDB" id="6335236at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00301">
        <property type="entry name" value="lipocalin_FABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018606093" evidence="2">
        <location>
            <begin position="20"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="49"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="227" mass="25469" checksum="0F010988E2FE7939" modified="2019-04-10" version="1" fragment="single">MASMTFATVALCALGCAMALPAPDFSYVREGQCLPMTSSAPLNYEKFSGRWVEVGSRPNILRRERQCRNFHFVISEDTPLRVTTGMDKENKLTEVITELVPKAEPSTFDVQIQGFSTSDLVVVDTDYTSFSCVYQCQQATPDRKVEWAFVYARELSQAAVAMKRASTSRASWPPRTRRRPATQRSKGRTGRPSCAVRRSDSSSFRTPTASPFRPSPALLPRPWLEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MG82</accession>
    <name>A0A3R7MG82_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001751">
        <property type="protein sequence ID" value="ROT75621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MG82"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIM-type" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="SWIM-type" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="42855" checksum="24D7AF1D28C13A0A" modified="2019-04-10" version="1">MFSTGPAFSNLNRYLPILVTALALALQESLPPSIRLLFVTIPPFLPRSVSLPPFLPRSVPSSCPPSLPPSFCLLFVYLPLSVSSSLPFRVPPFLPPSFSPLFVSLPPLLGLPPSFPPLISPLFVSSLPPSFSLLFVSLLLSASCSCPSFFHPSSASVSLLLSASCSCPPSFSLLFRVPPVFPSFFLSCPSFFQPPVRVPLFLVRVPPSFSSCPLLSPVRPSFVRVPPSFSLLFRVPPSFSLLFVSLLLSASCSCPSFFQPPVRVPPSFGLRVPPSSPVRSLLLSAQLLFVSLLLSLVRVKTVVRVPLLSASCSCPSSFSLLFVSSLLFVSSFFQPPVPSFFQPPSLPASCSCPSFFQPPLRVPPSLLPSFILSSSPTLRHGASPASHLRLCVNSKVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGF8</accession>
    <name>A0A3R7MGF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004331">
        <property type="protein sequence ID" value="ROT61147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGF8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="537" mass="58079" checksum="08D8436040622581" modified="2019-04-10" version="1">MTITVASVFPNPLASVCKIYLPLLSSFTLLPLFSSPFLHPPLFSFLTPSNSFLPILCQILPSPSPPSSLHSSLTPFLLLIPCHSLPPFFHSFLFSSLNLPSPIYLPLVTPFPPFFSHPHSSHDLNSLPPFIPFVHSFPPPSQSLIPLLLPSLSSHPSPPSILSCQLLPPSPIPTLFSSPPSPSILLPTPFPPLSSPSSLFSSLPSLYRHLIITPFRLLPPYTLSLFVTYALSHIKAYKFCVPTVQRLATLLTSPCPTLLPPPLVSSRPQPPPSSRPPRPLAYILPPHAPSLHAPPAARGPHRKVPGFCLFLASYSILNGFQRLTPNVFSSPAKETFDLAARDGASCLEKMKLRFAAISFLINGTIFLSPKETRSLSTLPPPPHPHPPSSPSPPPPPLPPLPPPPGPNSLWPPPPPPPLPPWRPRLQRSPDFLRRSACESADLGALLNRRGVISTPPSSTGVIHYPPHLPLPLHPPTHPLPFHPSTPLLHPLHPHPPSPPPPLPLPSSTPPPPPDPTCPGRTTSAPPRPAHFLPRLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGM6</accession>
    <name>A0A3R7MGM6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024736</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000883">
        <property type="protein sequence ID" value="ROT82114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGM6"/>
    <dbReference type="OrthoDB" id="6371836at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="286" mass="31119" checksum="A8B6A95ED2B3B50A" modified="2019-04-10" version="1">MMQEGGRQQRPPLPPPTKFEGIDPAPPPPPIDAPLAVVGDEGPAEYIDTATGKRTSQPKPCCGCRTCDFRFPLEMDEETSKVYREAKYCGLSYTFISSWCLMLVFGTVAAGGIVAVGFLDPKMLQYQIVGIVLAVAFGVGLPVFIVFWVCVQREARDIRRQYPSHEEQRTGTTRAPPSRERARGSTEGSKRAGLEALKMDGVPLGVLWCQCRGNASATPQFVLLHQQVLRMHEEAQNLGIWYVATTVTLYAVGVFYILARAGTLGTGALSSLAYCCSEAVSSILGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHW8</accession>
    <name>A0A3R7MHW8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPT2 homolog N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001581">
        <property type="protein sequence ID" value="ROT76990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHW8"/>
    <dbReference type="STRING" id="6689.A0A3R7MHW8"/>
    <dbReference type="OrthoDB" id="6259853at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054552">
        <property type="entry name" value="SPT2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22878">
        <property type="entry name" value="SPT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPT2 homolog N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="166" mass="18968" checksum="99A5376FE8078027" modified="2019-04-10" version="1">MDFSYLLELAKDNDQNNKKEISKSRFSTKVSAAKKLDRPSPKVGAIKALLEKKEEKKRKENEEFKKKRDNLLALRAQDRKANKRVNAMINRTKGACKAVLDDAKDITTARGEEQCDEDDYGYESAMSQQIFSKLADRYANMPEDDKLKFVKRSKGSIDDLKSNLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI82</accession>
    <name>A0A3R7MI82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosine-protein phosphatase 10D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003720">
        <property type="protein sequence ID" value="ROT62361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI82"/>
    <dbReference type="STRING" id="6689.A0A3R7MI82"/>
    <dbReference type="OrthoDB" id="8609993at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050991">
        <property type="entry name" value="ECM_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708:SF2">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708">
        <property type="entry name" value="TENASCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="31"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="167"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="52066" checksum="65DF5E30C88A7882" modified="2019-04-10" version="1">MSSLTCQVEILVARAGAAGFGCCWWSKKNGRAAACRTQLTIQKGKVVSVTWDPPVIGEYSSFKLKQIPLSEPQNSNKNIYITENQLPYQMREVTPGASYELQLFTVYENKESAAYVATNFTTPCFWPPFLPPQRRHNPFCSTPCTAKGQCRECLALPNGSRNLPAGPNAPGRFIVWYRNETTMLVLWQPPYPAGIYSHYRPPPTDVRSRGDLAASSPDLSLRSVLRASSCNPKRRERNQFAPPKYRVRFLFVLSSREYCVQMKRLALRNVSIDPSDAADSVLSVKKEGEPPGPAQAAFHGLVPGRAYNITVETVSQDQISEPTTAEYRTIPLPPRNVTFDLKTLTPFSFTVVGAPKGRGRVNRLYLVLLCLVTGRRSDWLRTVATFAGDRSAAVRFTTSFLPPLGLPFVREARRAVASEPSTIPQQHFKSWIKSVLAKGRACLHWALRYIPPHHRRPPARLLAPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIB5</accession>
    <name>A0A3R7MIB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ATP-binding cassette sub-family A member 3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_024356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000818">
        <property type="protein sequence ID" value="ROT82466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIB5"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF250">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="6">
        <location>
            <begin position="317"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT82466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="63332" checksum="E068D351A4D9F3C0" modified="2019-04-10" version="1">MADATENISKTRKRKRSLWNKLVLLMWKNLLLRKRHWVLTAFEILLPTLLFTLLLTIRVLPDSAFLPSYVNESVEFRTASECVLKKELCTKYGFWSEELRRCFVPDNIDDITLPTLAPSVIDGLEGLNLTEADLSDPESILTILENVNQMDPESINLEITQSILENLDPCILERFNDTSFEGMGPAEILGILGSLLSNISLPEFPDGSNFSYPGERKIFYGPPGGFSRGVAEYLADVLRLGHHVLTPVTSNEDLDTQVDKSYFATNDSFAAFYIGLFFNDLNDTEVPPQHLKYDLRLAGLWFTDLLYPFLQIPGPRDFTILTESYGMDGFTLIQSLVDRYYISQVTGEPQYRMQYRLYTQMYPYPPYTQDYGMSQFYGSALPTFVVLSLVLLSPSLIKSVVYEKETGVRELIRLMGLERWLVWFGWFLHSFIIILVVSTIMTILLKLELTPMDDTSGFLPPIIIHTDPFFMWVLFVLLWRVIHRLLLRCCRRSSAGLMDFEYNDLGLAPKILSCFLPNMAITWAFRIIAMFEGRSLGVQWSRLWDTGNPEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIY2</accession>
    <name>A0A3R7MIY2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">RING-type E3 ubiquitin transferase (cysteine targeting)</fullName>
            <ecNumber evidence="17">2.3.2.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Peroxin-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C7M84_022923</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-S-ubiquitinyl-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.36" evidence="17"/>
    <dbReference type="EMBL" id="QCYY01000627">
        <property type="protein sequence ID" value="ROT83904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIY2"/>
    <dbReference type="STRING" id="6689.A0A3R7MIY2"/>
    <dbReference type="OrthoDB" id="1701437at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025654">
        <property type="entry name" value="PEX2/10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48178">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48178:SF1">
        <property type="entry name" value="PEROXISOME BIOGENESIS FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Pex N-terminal" evidence="19">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00034523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ROT83904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="21762" checksum="0B2941FCAF9CAF90" modified="2019-04-10" version="1">MSAEDDTKRGFVPRISQLDSILLTDEAYSLIKSQVLTCVKYVGQNYLTRLEPEIEAGLRYILLRYTVQKARRSVGQQLLQIRYEDSVSLTRLRNYVYLLVFGRWVRQRAGDLAAGIFKKEGARVLASQCVNLLEILYKVAEVLNLLVFLHQVLPFYRTVLDVNIWPAITVFIPVMLQILHSVVLYAIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJG0</accession>
    <name>A0A3R7MJG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001399">
        <property type="protein sequence ID" value="ROT78321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJG0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="44609" checksum="61A1624DC0388A09" modified="2019-04-10" version="1">MRGCAHARALGHARLSAIHFHPLSPPHLSLLFLLLTITLSLLLPPFISSSSSSLPTPSPSFLSSSSPPFLSSSSPSFPLFISFPSSSPSLPLLLTNTLPSFPSSPTPSLSLLPHLPSSLHPPLSSPFHPSSSSPLLSLPPFLLLPTPLPSTLPPPLHSSPFHPSSSPTPLPSTLPPLHSSPFHPSSSSHSSPFHPSPPLHSSPFHPSSSSHSSPFHPSSPLPLLSLPPFLLLPTPLPSTHPPPHFSPFHPSSSPTSLPSTFLLSLPPFLLLPLLSLPPFLLLPLLSLPPSSSFPHLSLPPILLSPLLSLPPFLLLPAPLPSTPLPPSLSHFVPSRLNIPYSTFPLSLLCLYARKFRPSYHSSTGFGRPVAPLTLSPYPPHLLRPPHLPSLPSLSTLPISPSPPAAPPSPPLPRLRLGYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MN56</accession>
    <name>A0A3R7MN56_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">POU domain protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_025394</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the POU transcription factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000970">
        <property type="protein sequence ID" value="ROT81454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MN56"/>
    <dbReference type="STRING" id="6689.A0A3R7MN56"/>
    <dbReference type="OrthoDB" id="6358449at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048813">
        <property type="term" value="P:dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002805">
        <property type="term" value="P:regulation of antimicrobial peptide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000005">
        <property type="entry name" value="POU domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.40:FF:000001">
        <property type="entry name" value="POU domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013847">
        <property type="entry name" value="POU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000327">
        <property type="entry name" value="POU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050255">
        <property type="entry name" value="POU_domain_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636">
        <property type="entry name" value="POU DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11636:SF89">
        <property type="entry name" value="POU DOMAIN PROTEIN 2, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00157">
        <property type="entry name" value="Pou"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00028">
        <property type="entry name" value="POUDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00352">
        <property type="entry name" value="POU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00035">
        <property type="entry name" value="POU_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00465">
        <property type="entry name" value="POU_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51179">
        <property type="entry name" value="POU_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="POU-specific" evidence="11">
        <location>
            <begin position="136"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="226"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="6">
        <location>
            <begin position="228"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="285"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="336"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT81454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="41598" checksum="CE75FB2D5298298A" modified="2019-04-10" version="1">MNIVNSQGYGHRDAHEMKYMPQQHAPVAHNPWVGLPHSEPNPWASMHTHPGIHQDIKPQPSEVALHHRPPHHMGHSWQPPVSSPYSLAASNTTSPLGHHAAAYGMLPPQMHAGHLRELHCESPVTPDHHIHHEVEEEAPTSDDLEAFAKSFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLQKWLEEADSTTGSPTSIDKIAAQGRKRKKRTSIEVSVKGALEQHFHKQPKPSAQEISQLADTLQLEKEVVRVWFCNRRQKEKRMTPPILNGPDTQVVNGTTPGPGQQMTPTSEYGQPRSVDIPRELKYPAYTHQTMHGSPTHLPPQHSPPGPLLSPQMPPHSVAPSHTITH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MYG8</accession>
    <name>A0A3R7MYG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative centromere protein F-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008838</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MYG8"/>
    <dbReference type="OrthoDB" id="6366291at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051310">
        <property type="term" value="P:metaphase chromosome alignment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043513">
        <property type="entry name" value="Cenp-F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018302">
        <property type="entry name" value="CenpF/LEK1_Rb-prot-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18874:SF10">
        <property type="entry name" value="CENTROMERE PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18874">
        <property type="entry name" value="CMF/LEK/CENP CELL DIVISION-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10490">
        <property type="entry name" value="CENP-F_C_Rb_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Cenp-F/LEK1 Rb protein-binding" evidence="3">
        <location>
            <begin position="2727"/>
            <end position="2759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="622"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="792"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2181"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2295"/>
            <end position="2324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2338"/>
            <end position="2380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2575"/>
            <end position="2816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="971"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1590"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1753"/>
            <end position="1967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2181"/>
            <end position="2203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2213"/>
            <end position="2223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2229"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2297"/>
            <end position="2324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2358"/>
            <end position="2380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2576"/>
            <end position="2587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2598"/>
            <end position="2612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2655"/>
            <end position="2675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2816" mass="321396" checksum="D3C2690BD0A94C8F" modified="2019-04-10" version="1">MSWFGSASEWKQGLTSSALSKVEELENQVDRMKRERTQKQNQIDTLQQALDKQKRVNEDKGKEKQRLEKEIEQLARSCEGLQQQLQKGQHDHITSNIALHLPRQTSGGLSESSGQSSEEVEALKRKIEELECENRDLQYRRAERESGVNKRGHSSVSKTPMKKAIETSDENPFKAPYVTPHKKGSGLAMSDGNPFKTPRKQLSMSSLPVASQSNAAGDEYTKQLEKMVDQYKKDFEDLRANSSSSTVDTTKYQTEIAALKTALDKAKSENSSLEKTIASLNEQVASFKSSKDELNEKLQKAENQLRTVRSEMDCQRHNSEATRKNLEEKAKERERELNSDITRMQADMAGLERQVKDLQTKLQQQETHARNNENALKASLDKATSQVATLEKDRNTAVSRSNQLETEVEKLKQNLEDTNKTVVQLRQEKDMISSQVSNLKLKLTASESSLEKTSHKLEAAEQQVESQKLALEQLQSEKDKAKKDAENNISRLTQEVNEQQALNKTLKTERDEAQATIQTTKEACDNKLAGINAMEAEVEEMKKKVAETNAAMEAVKSETTNTVETTKAEAAAEIKKIKEEAENMVQKAKTEAEKDINKAKEEAGETVNKCKQETADSIAQKEKETQMQLDQMKEQVSEAEAKVKAAEEAKKEAQEKEEKARGEKLAAELSVWEIEGTIDSFKDAAAQAQQKADVLNVQMESLQQEKATLEKHHDDLVKSKDDTIQTLTSTLQDKEKIIEGLEGSVRDLKKSLEEAATEREKIASEAEEASREQAEKLGLLTKSLEEMQEALEKEQKEVQDLSSRLKTEEEERSEVLKKLEEAGVAAEEQKEKILALEERQQELEAELHDTKEQKDHLQCKLEDMEKVHEEKISEFQTTIEENRQALEGKDEEVSGLKDQLEKIEEEKSELEEESEKFRKEKQEEMLHLQEALTLAEEHSSTLKGHVEILQSQVTQLSVSFETKVESLVQEKMQLSQQQQELMTSLEELTKEKDIKVEQIEKAEEDIEQLKDALQGKVEELQNISSTLETQTQNINRLEEEMQKTTAHVKDLEATKEALENKSKEAVDRCEAIIKTLEKKEEEIELKQAEAQALQEQLQSASERVEEANARIEKLEEEAIISSQKMSQLEMDLENISDEAEYKVEAVQSQLSQMKEESEATSSQLATLSQELEQKLNEMESLKSNIEVITKEKEATLTSLHEHQGLLDAERARYSEKVQEIEKVAKSLREVEEQAAALREAKAAYEKEVESQQTSMNCLKEAVSQLEVQKEEWKAELDTLQTSLSALKEEKALLAAEIEQMNTTNKSLTDQLENLQLSQESVESVKQELSSSLEAKSHECMELQAAQQQLEEKLQKEASGAEAAIANLNEEIVRLKSEIQTKESDMEELAKKLDAALEERQTLSLQSNEQRELLENAMRTLETTKKNYIDRVMYEEKCIESEGWREKVLKLEQECIKNNVDINELEELLLAEKQESARQTAIAKQAETHVKEIRKALDARIAVLEALLSSTQADLAGQCDSQATLAKEVNYLEENLRQMTNKWEVERKRAEAIQSDYENYRDVIVMMQQQRDDTTSDEMMKKENSDLIRRLNSVEASNQKLHSQVQNLRMKEQQLKAQLKDASEEKVKTNYSQEQLQTTEEELKKAEQTILELQQHLNITTEELEELRCNRTSDNNREAEERENEMAVLKDQIACLQTSLAAKEEELSHLSQEMAKLKSLQRDLPVTSESPRKDNSLVDIAALQTELNLARGQLTVSQDELNGLKCEVQESQDQLKQAMFDLRKTQEQNKLYQDMAQELEDKVNLLEAEMKSASEGKERMKEELEQLRSSSTVETFADSQADTIASLNEVIARLQEEHNNLKEKYSTLQKELQEVADNRNRLQELEDSHKKSEELAFLNEELSSKNDELTTKNDLLISRNEELAGTIEDLSTQINELVCRNDVLTSDNETLTKKEEEMILQLDDLMMEKQDLDTQGLTMSQRLDEAVSGNKELIARNTELVLQNESLLLENQELKGSIQERNQSQEDAEELLKLREKYENLQTENEMLEKKYDELKKLHEDSTKEREEIENDKKSLTDTMKNLEDVVNQHQTECQEYIKQIEKMEEENNKLSEQLQGASSERDELASKMQELVAKLETTVAEKEKCLKEYEELQSEKDSVVLEKEQVLSEKEQLQSKYEAVMKEKDDLASDKDNLHQENEKLSLEKQQMLSDRALLEEKSKETEEERESLQSQIDSFVSQKEQEQSQVESLKLENEKIVIEKQKLATLAEQSSMDIEELTVELKQVTSLKETLLLENEELRNKNEEQQKEKEKLSTDVELLRSEKEEWATGKEQLVKEKEQLKQDYENLQSQQPGRTEATVRTETRERRRQQQEEASLNKEVVRLQDEVQTANEELQVAKDNLTNKLSETTSLMVDKAALQVEVSQLKDKAASAEKLEKSVTSKEAKIEELGVLVKESRTDLDSLRAKFSLVQNIGRKKESELKECMKHVEQLEEEVEQLKEKVKETDTDATQCRKNLEETKQEVEHWQKRFNEKNGEAEQQASQQIEVLKKMHDLEEANDNMKSKVKLLQAQIKKLKAEQSQDKAQDLQKSVLKPAKSSPQLANPMQVTQRSEALESPEVIGSSQTQEPRLSDMPQVKSRAVTRMASTMKIPPANKSQQPSGVRTRRSLIQTVDENSLPEVLQSQGRKSLVADDDEMKRALKRVCASTSMSQEKRKRKSTVIPESPEAAVEGLPSKVKQGLNDLPSGAESPGVMRRSTTLVKKYDSNDKSQVGGPLKSLSTNSPIRPSERRMTRASIGLRGKPPQPAARSDECKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NAB5</accession>
    <name>A0A3R7NAB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_025160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000935">
        <property type="protein sequence ID" value="ROT81677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NAB5"/>
    <dbReference type="STRING" id="6689.A0A3R7NAB5"/>
    <dbReference type="OrthoDB" id="25872at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015245">
        <property type="entry name" value="Tap_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09162">
        <property type="entry name" value="Tap-RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear RNA export factor Tap RNA-binding" evidence="2">
        <location>
            <begin position="143"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="NXF1/2/3/5-like leucine-rich repeat" evidence="3">
        <location>
            <begin position="240"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="369" mass="42200" checksum="E8521B3DF240248D" modified="2019-04-10" version="1">MRKRHTCFLAPSSPPPSLPFPGSHPLFILPLNAPHLLSLHLDPPPLSLSFPRLPPPLLSPPPRPPFSPLPPDPPPFYPPPPRHPHLLSLPPSPSSPLLPSPLPLPHHPVRWQGMYKTRGGRRRMQDTRNPRNNPNTSTSNMGWHKIIIRDGCMYDKNEVLDNLKEYVEEPFVPILYEVEGNSLVFYLEDNGAAAKAITNVNRRVTMRNGSRLIICNNRSPPPNRPLSVQQQEKVMHIMSERYCLELKRLDLKNFHNAPSLMQIFFPLYRTPNMKIIVDIIIQNIPQVEEIDLSCNKIHTLEEIERIIPVCTNLKRLNLEKNKLMNVDCLAKLQGLAIMELSLEGNPLCDKFTDTETYFRQVTFVVFQVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NCF5</accession>
    <name>A0A3R7NCF5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative pro-resilin-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000685">
        <property type="protein sequence ID" value="ROT83446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NCF5"/>
    <dbReference type="OrthoDB" id="6630425at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF79">
        <property type="entry name" value="CUTICULAR PROTEIN 50CB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018535419" evidence="3">
        <location>
            <begin position="18"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="116" mass="12572" checksum="3B490BE636AD5C38" modified="2019-04-10" version="1">MIYQATVILVVLVVAHAFPGNYGPVYASVPLPYGFNYAVNDAYKGTNFGQSEKSDGNSVWGSYTVALPDGRKQTVDYTADHGRDSWPRSASPARLSTPKFLVLPSSSLKTEADIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NMZ6</accession>
    <name>A0A3R7NMZ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019848</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003730">
        <property type="protein sequence ID" value="ROT62303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7NMZ6"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06526">
        <property type="entry name" value="metazoan_ACD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001436">
        <property type="entry name" value="Alpha-crystallin/sHSP_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640">
        <property type="entry name" value="HEAT SHOCK PROTEIN HSP-12.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45640:SF26">
        <property type="entry name" value="RE23625P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="88"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="254"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="426"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="587"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="762"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="952"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="369"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1491"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1583"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1797"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1916"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1970"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2039"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2136"/>
            <end position="2235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="369"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1590"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1802"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="2039"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="2136"/>
            <end position="2234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT62303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2308" mass="248301" checksum="3F3AC0E6E281D062" modified="2019-04-10" version="1">MSSVQKQTTTRTVKQQSSETSGVTQTSTTTSRQTNRVQITQRGLFFDDACFEDTRNDFRNAISDVVSRFGDKSSNIDELTQYRSLRSREIRDENQAITSSQDDSKYKIVVDVQDFVNGGEINVKVVEEREVVVEGRVQKVEGNRTSSKSFQRSFFLPEDVDVDTLASVMSADGVLTITAIRRTVTQQLTQVPVSIQRVENRQVTTTTSTTGVQEVPVPVQPVQDTNQTVSVQKKMNIQTANTDEISTYRNLRQRELREETQAATVNEDQTTHKVVVDVQDFINGGEVNVKVVNEREIVIEGHVEKKEGNTTSTKRFRKRYVLPEDIEVEKVTSVMSSDGVLTITTPKKPSALPLSEVPVSIQKIENKKTTTTTTTTGVQETPAPVQPAQPIQPSQDTDQTVSVQKKMNIQTANTDEISTYRNLRQRELREETQAATVNEDQTTHKVVVDVQDFINGGEVNVKVVNEREIVIEGHVEKKEGNTTSTKRFRKRYVLPEDIEVEKVTSVMSSDGVLTIKTPKKHLSHFRSRPLIAKQRGRERSVFRRPGDRCRQADHQTHTRPHHEVLQKMNIQTANTDEISTYRNLRQRELREETQAATVNEDQTTHKVVVDVQDFINGGEVNVKVVNEREIVIEGHVEKKEGNTTSTKRFRKRYVLPEDIEVEKVTSVMSSDGVLTIKTPKKPSSQPLPEVPVSIQKIENKKTTTTTTTTGVQEIPAPVQPAQPAQPIQPSQDTDQTVSVQKKMNIQTANTDEISTYRNLRQRELREETQAATVNEDQTTHKIVVDVQDFVNGGEVIVKIVNEREVIIEGHVEKMEGNKTSIKRFRKRYVLPENIEVEKVTSVMSSDGVLTITTPKKPSSQPLTQVTPVSIQKIENKKQETITQETKTTTDSSVTDVPSRLLTIIKKGNFFSDTFFEDCRQNFQTAVIQILKKLNIETSTVDVMTTYRTVRQRELREETQAITEKESEQVRKFVVDVQDFANGGEVTVKVVQEREVVVEGRVDRQEGGVTSTKRCKKTFILSENIQVNSVTAVMSADGILTITAPKKVTQQQQVTVEKTTDTKKEVTKEAVVQKPGEDRVLPVNKKGSFLSDPYFQDSRQDFQSSVTEVVMKSTEKDSKEDHMTIYRRLRQKTIKLENQAVSVKEDAQFQKIVLDVLDFMNGEVKVMITSENILVVEGRGTRQEGVKTSSHSFLRRFIVPDNFQGPGKRRRAKIPCDMNVSAAMRVSPRQLCEDALTPGYYGLAVYKQPDSLLHVGSPRWHFAIPCPPPTPPGSPVAPPGSPCRPPWLPLSPSWLRPVALLAHPAALWPPSVQPLSGSSPSSAALPAASWLLPPSAALLAPPPLCRALLVPPSPPPTAFLAPPPPTAFLAPPAAPPGPLSSVVTFLASPPAALLATPAPVRPPGSPCPPSWLPLSPLTGSPCRPPASPVALLASPAALLAPSPASSSPSLCCRPPWLLPPAASLASSPLCPPGSSPLPPSWLLPPLCRPPGSSPPNRLPGSPPYRLPGSPPCRPPGSPCRPPGSLVTFLAPPCRPPGYPRPCRLLAPPAALLAPPVALLAPPAALLGLWSPSWLPPAALLTPPAPPPSGSPRPCLLAPRRPSGSSPPAPWLPPCRPSWLPCRPPAPPVALLAPLSPSWLPLSPSWLPLPPSWLPLPPPALAPSWLPPAALPGSPCRLWLPCRPPGSPCRPPGPLPPSCLCSPSWLPLPPSWLPLSPSWPPCPPSWLPPAAILAPPRLLGLCHLSWLPPCRPPGSPPAALLAPLSALLAPLSPSLAPPCRPPGPPVALLAPPAALLVSRSSGSPCPPPGSPPAPAAPPPAALLAPPAALLAPPPLPPSWLPPCRPPGSPPLLPPSWLLPPPCCRPPGSPLRPPAPPLSPSWLPPCHPPGSPVALLAPPLPPSWLPHAALLAPPPPRPPSWLPCRPSGPPPCRSPGSPPAALLAPPPLCPLLAPPPPLPPSWLPPSLPLPPPPPVALLAPPLPPSGSPPPRPPSWLPLPPSWPPAALWLSPPAALLAPPVRPPGSPCPALLAPPLPPSWLPPCRPPGSPPARPPGSPPAALLAPPCALLAPPPPSWLPPLPPSWLPPAALLLPLPTSWFPPLPPSWLLPCRPPAPPPAPSWPPPAASWLPPAALLPCRPPGSPLPPSLAPCRPPGSPRPPAPPLPPPAPPLPPSCPPPPPSASPPPFLAPPPAPPLPPSGSPPCRPLPPPPAALLAPPLPPSLLPPPLPPPAPPPPAALLAPPAASCLPCRPPAPPPLPPSWLPPCRPPWLPPPLPPSCPPPPRPCPPLLPSCPPPAALLAPPLPREPSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NZX0</accession>
    <name>A0A3R7NZX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002296">
        <property type="protein sequence ID" value="ROT71449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NZX0"/>
    <dbReference type="STRING" id="6689.A0A3R7NZX0"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039195">
        <property type="entry name" value="ANKRD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24192">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24192:SF3">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="282" mass="31195" checksum="7733F4B8B2318CD0" modified="2019-04-10" version="1">MDTQKQNEEKLREACCYGDNEAVIALVTRGANINSRHEINGWTGLHWAAKRGNLETVRWLLANGADPKLTNNQSQTPAQLATNPHILQLLAPSSESLPITPSYMAHPPPINQTSHSTNSPPSKPLTNGITEVNGYPGTGSLPSNNNPSTSSCVPRPGMSPSPALELTQNKPKELVLKVRVANTDDPDFIEIDFPITHMNFSHLLTVCCKELAVNPQMVERIRKLPNTRLRNDKDVKRLENFTELELVIKGQSRPAITRSDSHSTSKNSYQSISSFKNQTILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P189</accession>
    <name>A0A3R7P189_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P189"/>
    <dbReference type="STRING" id="6689.A0A3R7P189"/>
    <dbReference type="OrthoDB" id="6381572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008042">
        <property type="entry name" value="Retrotrans_Pao"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05380">
        <property type="entry name" value="Peptidase_A17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="48731" checksum="291C797497C1B926" modified="2019-04-10" version="1">MAAFKAVTWWKFGSFSVQPEIDGSQYGNEVIEVIRRNFYVDNLLIASDDKESMKQLVKDLIDLCAAGGWRLNQWTSNNKNILATIPEAERDISVASLDLSKDELPMERTLGMHWSMENDYFTYKIKPNDKPLTRRGVLSVVASIYDPLGMVAPFTLPAKLLLQDMCRQQLGWDEEMETAEVTQWKAWLNQLPKLRNFKVPRSFIPMSFGTVRSCQLHHFADASQVGYGIASYLRLESATGEVYCTLVMGRSRVAPLKRMTIPRLELTAATVAARMDQKLRSELDLRLEKSVFWTDSTSVLKYLFNEKARYQTFVANRVNLIRELSPIEAWRYVETRSNPADLASRGVDMDSFLASSIWITGPTFLSENEKMWPILPNDVKRGTLEDDSEVKPPQLVCETVITAMSFIEEIASRFSNWMTFVHCIAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFT8</accession>
    <name>A0A3R7PFT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative diuretic hormone 44 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_006455</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000182">
        <property type="protein sequence ID" value="ROT85796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFT8"/>
    <dbReference type="OrthoDB" id="6022368at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008036">
        <property type="term" value="F:diuretic hormone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017046">
        <property type="term" value="F:peptide hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.10">
        <property type="entry name" value="GPCR, family 2, extracellular hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050332">
        <property type="entry name" value="GPCR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002001">
        <property type="entry name" value="GPCR_2_diuretic_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036445">
        <property type="entry name" value="GPCR_2_extracell_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001879">
        <property type="entry name" value="GPCR_2_extracellular_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620:SF15">
        <property type="entry name" value="DIURETIC HORMONE 44 RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45620">
        <property type="entry name" value="PDF RECEPTOR-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02793">
        <property type="entry name" value="HRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01127">
        <property type="entry name" value="DIUHORMONER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00008">
        <property type="entry name" value="HormR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111418">
        <property type="entry name" value="Hormone receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50227">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 1" evidence="11">
        <location>
            <begin position="12"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="12">
        <location>
            <begin position="97"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT85796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="207" mass="23297" checksum="56FAAE77FBD37A72" modified="2019-04-10" version="1">MLGRGHNLSSLCPVTWDRVTCWPFTSPNTIVHLPCMRELNGVFYDQRDNVSRFCQSDGTWEPRSNYSACQPVVPSLHNTTDRIVAGGMRDVTLSENLATLHLLGYAVSVAALGIGLFIFIRFKDLRCVRNTIHIHLMLTYLLLDTCWLLAATSQMLTSRAGGQMFCSLVLIFHFLHLANFSWMFMEEDAKRSSYGDDASPLNLGAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHC5</accession>
    <name>A0A3R7PHC5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002924">
        <property type="protein sequence ID" value="ROT66506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHC5"/>
    <dbReference type="OrthoDB" id="6398195at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="28259" checksum="DAE96AD68D9DF38E" modified="2019-04-10" version="1">MATMQMFGRTGNKKTGIILAVIGGLMFAIGIALVITGAAMPCSFDEDDWDYDCNSKLPLFITGGFMLPFALIILGLGLTIICYIRHASLITSVSTRTDMHISHQYGTTTVSAQRTVGNSPYPQQAAVPQYSQQAAVPPYPQQEAAPPYSQQAAVPPYPQQEAAPPYSQQAAVPPYPQQAEAPSYPQHDSVPPYYPQKESGPSYPQQATAPTYPQQAAAPPYPQQAAAPPYPQQAPIPPYPQQAPGLPHEQGPDQPYPEKSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLE3</accession>
    <name>A0A3R7PLE3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tubulin-specific chaperone cofactor E-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001749">
        <property type="protein sequence ID" value="ROT75646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PLE3"/>
    <dbReference type="STRING" id="6689.A0A3R7PLE3"/>
    <dbReference type="OrthoDB" id="5855206at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15140:SF6">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15140">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="47996" checksum="E88B5D918F14BA59" modified="2019-04-10" version="1">MPSLPEAVDLKYGDECPDAQVTEVACVALTLKRSGRQRLPSVLILSECDIEKAGDEEEVERKCEGVRELDLSRNKLKEWSEVFKILRHLPTLGFLNLSYNSFETSLADSPDVVGLTNLTRLVLNGTTLPWKDVHVLLDNAPRVEELHLCKNDYKKVEKPRKKYVTVSRVHFNNNPSTEWSEIEALGQMFPSLEVLILAECPLSKLTEEEHFKEYFQNLKYLSLNNTKISSWDSVDRVNWFPNLAELRLQQCPLYEPYKDEERRQLTIARLWRVERLNGGALITPEERENAERAFIRHYMNSEVRPRRYDELIMQHGELDPLVEVSLQPEKEVAVTIRFGETAFQRTLSVYSRVLDVKKALEPEVGLPPSKMRLFYHDKVIHYGPEELKINSKQLYTMNIHSGDEFIVEPKVCKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLX0</accession>
    <name>A0A3R7PLX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PLX0"/>
    <dbReference type="OrthoDB" id="6341775at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018524596" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="158" mass="17558" checksum="A4D5B02BD5F18851" modified="2019-04-10" version="1">MKYDYVILMSLTLLWFPAPVTLLEVSRKLPLEEESAFLKGGAEFGNRQDIWSSLHTFCDLHCGKNDEMLTEDYQSANMSAANMQIGRRLFQKLYPRASSKRPAVNNRKVNRDPGGGQIGSALSAALPDARCTGGGWRNHVALLTSRPILLLLCSLSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PS71</accession>
    <name>A0A3R7PS71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001793">
        <property type="protein sequence ID" value="ROT75283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PS71"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41354" checksum="A2D1480CE9B75362" modified="2019-04-10" version="1">MPHFLSASCLRSDTFLRLPARRYRSTYQLLCFPLFTLSLTFSLLFLLFFFSFPSPFFLSSMSSPCPPPSAFLPHCFHHFFFLSYLSIAFLSGSPSYSSLSIPSPSSQLPSRFLPSISYLPCLLSPRLSPLPFLIPPFILLSPFPPLPFNSLPVPPLPLLISSDFPLPYSIPSHFVFFFFLLHLSPPPSISLLLLPSSPLPSIPLLFLPSLSSSFHLSPILYYSPLLLSTPLLFTLHLSPPPPISLFLSPPLPPPSPLPLPLPSPASPARHPEWPLPSLFPSCSLLPFSLFSSSLFLIPFFPSPSSLISPYSPLPFSFLPLPFSLSPSSLLPPPLPFSLLPLPFSLFPSSLLPPPSSLLIPLFPSPSSIFLFFILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYR8</accession>
    <name>A0A3R7PYR8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative melanoma-associated antigen C1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000994">
        <property type="protein sequence ID" value="ROT81293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYR8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="56472" checksum="53A802E8B1BA0C4B" modified="2019-04-10" version="1">MKRRKQTVIVFQNGDSGTANHNKPRVDSQPISEQRGFGNAHTLFNDVSSAKPATRPQNPPLVRKTRHSSANPPFRNSSKPATRPSLIRKTRHSSAKPATRPQLIRKTRHSSATHPQNPPLVRKTLAHSSSAKTRHSSALIRKTRHSSAKPATRPQNPATRRKTRHSSAKTRPNSSANPPLVRKTRHSSAKSSAKPATRPQNRHSSAKTRHSSATHPQKPATRTHPQNPPLVASAKPLVRKTRHVRPQNPPLVRKTRHSSAKPPLVRQTRVATHPQNPPLVRKPRHSSRKNPPLVRKTPPLVRNSSAKPATRPQNPPRPCAKPVRKTRHSSAKPATRPQNPPLVRNRKTRHSSAKTRHSSQLIAQNPPLNPQNPPLVRKTRHSSAKPATRPQLIRKNPPLVRNPQLIRKTATHPQNRHSSAKPPLGTTATRPQLIRKPATRPQPALVVRKTRHSSAKPATRPQKPATRPQPKPPLVAKPAKPATRPQNPPLVRHPSRPESKSLSRGRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1F8</accession>
    <name>A0A3R7Q1F8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Testican-3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023336</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000677">
        <property type="protein sequence ID" value="ROT83493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1F8"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1F8"/>
    <dbReference type="OrthoDB" id="8875634at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005518">
        <property type="term" value="F:collagen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050840">
        <property type="term" value="F:extracellular matrix binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13866:SF30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13866">
        <property type="entry name" value="SPARC OSTEONECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="10"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="155" mass="16779" checksum="AD55DFDD51194BF9" modified="2019-04-10" version="1">MGDQRLNRRPFAEKQCPSCPVVRPVFLCGSDNRTYSSLCRLHYHNCIHEANVHVACKGFCPCKGGTLLFIGLTLRHYLGLNSRAKGKIGLDVDEGKGPAPLESRHAAPTAKGRAPHGQSNAEEPPLCVWTQMTNGAKVGYGRPHSSLRDTNCAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3Z6</accession>
    <name>A0A3R7Q3Z6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative beta-1,4-glucuronyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002736">
        <property type="protein sequence ID" value="ROT67950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3Z6"/>
    <dbReference type="OrthoDB" id="9974378at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47412">
        <property type="entry name" value="FI01434P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47412:SF1">
        <property type="entry name" value="FI01434P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="51094" checksum="DC2643A3F11E97BC" modified="2019-04-10" version="1">MMASARALVVRGSLFLNAVLVLYLCLSWLSTTPTTRLVPSSSALRGVSSAPPLPALPMPGAAEGADEGVAAPPQLAAGSPAAPPLAQQGSAPLHLPPLSPELLPEGAAAPAELHDMSLGGRRTLRPEEPPREVQESAGVTEQLVAEPIVTEPPDPPLDSQERKMYGDLRECSTRSLRPFYQQRGDYWVLENYVPAALAFRCDESITYTTHGDFTFLDNLEPLTSRWQGPVSVAVYAPGTDFNDTVNTILYLRDCWAEGIKKYVTFHLFFHVSHTPKKVPTTEELLRRKTDCAQEPPRWTNVTTYRQKKKLLYPVNVARNTARQAVQTYFVLPSDVELYPSVNFIPEFFKMLKKPDVSNSTNPRVYVFSIFEVRDNVTAPETKGDLQRMLKKGDAIPFHKNVCAKQPLTAPSLPRSGSPRRYGRGCRCSTWASASRRTTSGSPSTSAPTRSPCTTSASPGRARATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q411</accession>
    <name>A0A3R7Q411_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-type ATPase A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_012527</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000259">
        <property type="protein sequence ID" value="ROT85511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q411"/>
    <dbReference type="STRING" id="6689.A0A3R7Q411"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000023">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="174"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="628"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT85511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="662" mass="73515" checksum="A4858190742012D6" modified="2019-04-10" version="1">MVSWDEGVRALNHGTKDELDMYDQLWEEKVVREEVATEDQKGTQSRVYFINKKIKYVWDEATCTFVRLRPLEHGTTFNTFHRQSGGLSEPAAKAKKALFGENFMKIEILSIWQLIVQQAYNPFYIFQAYTVILWCMQAYYLFAVCIAVLSIVTITIMVWETRRQSRALRKTVTSQSQVTVLRDGQKTSLSSRELVPGDVMLIADGLGRMEVDAVVLQGSVVVNEAMLTGESVPITKVAIPKESDTMFCEEEHKRHFLYSGTEVLQVRGGQELPVLVVNTGFYTARGELVRSILFPKPIEHHFYGDFLKLLGVFLLIGLGAMVWSFFQWSKIKGSWDVVFLSLDLVTFVVPSVLPATITAINACTQQRLKRKDVFCLSSNYISLSGSVDTVCFDKTGTLTEDDLALAGVIPCTEGDMGSPVEDVSQLQVEQPLTRALATCHSLTSINGKLVGYPIDTKIFSGIGWNLLESDPAVNQDYGMVALIRVQPPPGERVLPEDHEVAVLKTFPFEAKEQRTTVVVRRRASRLRGLRQGARREVPGITEAALEWYTRQGLRVVAVAGKSLQEGLEWEKVDLTPREVLEEGAMFLGLVLLQNKLKVETAPVLAALHQADITTVMITGDNLLTALSGPESILRPPDDRREGADGCGVGEGSSASSGLLLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBU3</accession>
    <name>A0A3R7QBU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001956">
        <property type="protein sequence ID" value="ROT73984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBU3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018757394" evidence="2">
        <location>
            <begin position="24"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="44854" checksum="90FEA573B650D2AA" modified="2019-04-10" version="1">MEFNVASGRIVLGILLVLSIASCDLERTRNPRDTQGRTQGRVGTRGPPRFPRDSRPRRPRCPSATRNLTLTKEVVLELLQEVAHYLRASELVLVIRREYYDTCISLGKNLYRRGMPTSCTNRTTLQGYYHALVFLELLQKDDPPLSSILEEITEITEEGRLQVLHLVFITDKRVPAPSVNASLSFCLIQPRENQIEFREVLTFGGNPPGQPAEDVASLHSSIIPPTSSLLFSPYPLPHFSSIFFFSRPTSVYSAPYPLLFFSPFPFPFSHFPISPTPPLFPSFPYPLFSFHPYPPPIPPPLFLVSPHPLHFFSLPFHPDPLSLPQLFSPQSPLSSLFFSPHPLPTHSFSPIPLPLSLFPFPFQAAPYTIVTTSPTGEMQVEGYLVDLLGVLQQHLNFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE20</accession>
    <name>A0A3R7QE20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005699</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001737">
        <property type="protein sequence ID" value="ROT75758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE20"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="50443" checksum="1DC2E9BC1F446C74" modified="2019-04-10" version="1">MTETTSASSPPFPFLNFCISSIAYSTVIAYFSLPFFEFSFRVHLYCLLSSFLFFPSSSPSPLSAFSFLPLYLTSFPLPPFSFSLFFSPFVHLLTFFLLHSQLSPLFCFFLSFPPLSLASFLSPLFASFSSSPLSTFFTSSSAPSTVSSLYFLFSSVPATVIASFPPPSLLLTLITYISVYCSVIASLLPPSYLTSLPLFHPPLSPPFCLLLRYRAPSAAPPFIASTSALLLCYQLPSTSFILYSTHRYHLLLLLCFIHRYHLPSTSSFSSAPSTVITSLCLFLSLSIHRLSFLPPSINSLLPPPFPLFHPPLSPPFCLLLCYQLPSTSIPSSSPLLHPPYHPPFHLLLLLYPTHRYHLLLLLCFIHRYHLPSTSSFILHSTHRYHHPSSSAHPYHLLLLLCSTVITPTVSPPASPPAFIHRYHLPSASSFSSRPLSLPRAPPDRRGDLRRVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE98</accession>
    <name>A0A3R7QE98_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Salivary glue protein Sgs-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003215">
        <property type="protein sequence ID" value="ROT64652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE98"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="578" mass="62661" checksum="27EA9D580E4A36BA" modified="2019-04-10" version="1">MSRFTCRGSPFGIHLSGFTFRDSRDFGIHLSGSPFGIHLSGSPFGVHLFVVSPSGFTCRGSLSGFTFIVTSGFLVGVHLRDLVRGSLFTGISLSGFTLRDSTCRGSPFGIGRVTWVHLRFTWWFPFGDSLVVGFTVVFHLSGFTCRGSPFGIHLSGFTFRDSPFGIHLSGFTFRDSLVGVGSLFGVHLSGFTFRGSPFGVHLSGFVSGFHFSGFTCGFTFGITCRVFTSRFTCRGFTFGVLSGFHVVVVPLSGFTCRCSRYRGSPCRGSPFGDSLVGVHLSDSLVGVHLSGFTCRGSPFGAHLSGFTYRVHLRVHFRGSPSDSLDYRDSLVRGSLSGFCRGYIGRGSFSFGVHLSGFTCRGFHFTGSPIGVSLLSGFTCRVHLRVHFSGVHLSFTCRGSPSLCRGSPSFICRGSPSGFTSGFTFRVHLSGFLFRDSLVGFTFGFICRGSPFGTFTLSGFTFRGSLVGVHLSGFTCRGSPFEVHLSGFTFRGSLVGVHLSRFICRGSPFEVHLSGVHPFEIVGGSPFEIHLSGFTFRGSLPSYSSPLVHFRFLSIFLSRQDSTLLHKISINHSADVTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QI49</accession>
    <name>A0A3R7QI49_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002711">
        <property type="protein sequence ID" value="ROT68175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QI49"/>
    <dbReference type="OrthoDB" id="427030at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="73188" checksum="66042F3F938B6163" modified="2019-04-10" version="1">MICCRDPQVMEALALDVTSLGEEGAQMITLVETASLEDDATQHNVHILTANQLENDSPDHLQDNPHAQMQHNSVHQSIVPKVLKSPHCLVCNAKLGVSARGAMEVFSDRAKTSHRQLQVHAVLSDIVNQELNPIAIHSSIVCKKCFKLIDDIDSMEGQLINMKQVVTNKYLRTLALVKQDLTEDSVDRVLEEDSLNLEAANLAKDDKDFKVYMGLGGNRARRGRRGKGRGRPASVKLEVKQEESVEVITGLAASESVETLKHQEVCVQGLLSSSDSNDGLGAHLEESLEDDGGADMLMVEEEILDDSAVAEAVEDVMEVDGLDLEDTDGCVQIGSLTLPTLTPHGLGVEHDSQDMSEEHNLLDDGVEKYKCRFCSLKMSVLVEIQRHMREHGHTENLEGYMKVNPPTVVAAENGEGVPSPSGTVRTMKLDDEQSLEPSLDTPVQLVRGGVRDGETVEVVSRPVHIIETDDIPRYIIHTTGTGERTEEGVGHFFASLQGQVVEVRAEDIERYTDLTSDQMTHVAQVAAQVVTGQTSNNGIQQVAVSSDLRPFHIQLEPATREITLQTQASTAREVTASIGVPTATTVTTREVTLPSGSQVQGTPGTAVLVGNRQVQYEASGLGQGTLRKVLTDREEIRTISVHNMTPTTDTRTVRTWPQQTINTSTPNFIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKZ5</accession>
    <name>A0A3R7QKZ5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phosphoglucomutase-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_010926</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002387">
        <property type="protein sequence ID" value="ROT70769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKZ5"/>
    <dbReference type="STRING" id="6689.A0A3R7QKZ5"/>
    <dbReference type="OrthoDB" id="8300170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05799">
        <property type="entry name" value="PGM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000017">
        <property type="entry name" value="glucose 1,6-bisphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000035">
        <property type="entry name" value="Pgm3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745:SF1">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745">
        <property type="entry name" value="PHOSPHOMANNOMUTASE 45A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="12">
        <location>
            <begin position="53"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="221"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="352"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="497" mass="55414" checksum="6DE9D9CE0E077E47" modified="2019-04-10" version="1" fragment="single">MANLKIDTGKPLLDEKIAEWLKWDKNEVTRADVKQKVQRGEVDQLEKIMAHRMVFGTAGLRGRMGAGYALMNDLVIIQTSQGFSKYLTAVNPKARTKGVVIGHDSRHNSHRFARLAAAAFLNNGIPVYLLGKIVPTPFVPFTILQYGAAAGVMVTASHNPKEDNGYKVYWENGAQIIPPHDSGIQKSIEENLSPWEDAWDVEKALADPKLTDPLDDISNKYFSKLGSSMLDKEKNQASPLTFTLTAMHGVSHDYMVEAFKVCGFKPFVPVKEQMVPDPEFPTVKFPNPEEGKSALDLSFKTANENGSSVILANDPDADRLAVAEKLPSGQWKVFTGNEEGALLGWWAWQRSRQLSPDIPTSDCYMIASTVSSKILRAIASKEGFNFEETLTGFKWMGNKAHDLIKDGKTVLFAFEEAIGFMNGSEVLDKDGVSAAMRLAEMATVLKADHNMTLFDKLQDIYKTYGYHVSNNSYYICHDQRVINKMFERIRNFNGPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QL65</accession>
    <name>A0A3R7QL65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCP-like extracellular domain containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002369">
        <property type="protein sequence ID" value="ROT70930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QL65"/>
    <dbReference type="OrthoDB" id="414826at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP" evidence="1">
        <location>
            <begin position="181"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="39324" checksum="9D320158AB0068BF" modified="2019-04-10" version="1">MCERLQSADTGEGAGLSRNVGLRKCLYNDILYKRNTVIENLPEACAQLVCRMKRRKPKVVLEPVEGCTCSRSASRVPKVESEPEGGDVASDAFYDTGARAARSCWFNRRRRVNSTVAILEDHCVGVVCVYNASAARAVLEARFLPGCVCGACDYAQFSAEHSMLLPPNPECNAHRSGVSEAEKLEILEAHNTLRAKVARGEESQGDSGPQPSGADIRELVWNDELAQVAQAWAEQCKGGHDGYAKRKICSRDYAVGQNVFRKWGHNPDSVWTEAIQSWYNEVANMPHTFVDQFTGSPPSGKIIGHYTRIKSGTTYPESKVYVCNYGRNGNSINSPVYTRGPAASECSGGESTRYPGLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QP64</accession>
    <name>A0A3R7QP64_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phosphorylase b kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_013527</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Glycan biosynthesis; glycogen metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cell membrane</location>
            <topology evidence="2 13">Lipid-anchor</topology>
            <orientation evidence="2 13">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the phosphorylase b kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000269">
        <property type="protein sequence ID" value="ROT85471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QP64"/>
    <dbReference type="STRING" id="6689.A0A3R7QP64"/>
    <dbReference type="OrthoDB" id="5971574at2759"/>
    <dbReference type="UniPathway" id="UPA00163"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005964">
        <property type="term" value="C:phosphorylase kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005977">
        <property type="term" value="P:glycogen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000004">
        <property type="entry name" value="Phosphorylase b kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008734">
        <property type="entry name" value="PHK_A/B_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749">
        <property type="entry name" value="PHOSPHORYLASE B KINASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749:SF7">
        <property type="entry name" value="PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="10 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 13" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="11 13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12 13" id="KW-0636">Prenylation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH15-like" evidence="14">
        <location>
            <begin position="8"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT85471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="630" mass="71852" checksum="13DD0EF7D1CBE474" modified="2019-04-10" version="1">MRSRSNSGVRLDYYHRIVYRTILRHQDAVTGLLPASNLNDHAWVRDNLYSIMAVWGLSMAYKKNADLDEDRAKTYELEQSCVKLMRGLLNCMMQQLDKVEKFKHTQAPIDSLHAKYSSKTGQIVVKDNEWGHLQIDATSLFLLVLAQMTASGLQIVFNLDEVSFIQNLVFYIESAYCIPDYGIWERGDKTNHGLPELNASSIGLAKAALEAMNELDLFGARGGPASVIHVLADEAQKCQAVLQSMLPRESNSKEVDSSLLAVISFPSFAVDDPMLIKLTRDTIQDKLQGRYGCKRFLRDGYKTAKEDPSRLYYEPWELKRFEKIECEWPLFYCYLILDYCFQNDKEAVKEYAEQLEELLVTTDDGLRLVPEIYTVPAENVEQEYKEPGSQDRVAVGKLPFMWAQSLFIMGRLLQDNFLACGELDPLNRRLGSEKKPDVVVQVVVLAEDSSIQAKLQALDIPVQTIAEVAPIEVQPARVLSKLYAHLGRNQKLGLSGRQSRDVGILSTSKLYSLQDRIFAFTPQYFDYDESYLSNDVDLGMYCYAAALDYLRSTWKDIGRPTSVDTEEWYAMHDINLLCYYLKSHVAFLKETWFSSMLGRPTITYLVQSFMLVRRTRLAASIRAIIPSPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRW0</accession>
    <name>A0A3R7QRW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative carbohydrate sulfotransferase 1-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001706">
        <property type="protein sequence ID" value="ROT75958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRW0"/>
    <dbReference type="OrthoDB" id="5987729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="1">
        <location>
            <begin position="190"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="41164" checksum="9D408ECFC69E5FEE" modified="2019-04-10" version="1">MPLPADATETSHEPLKLPEDEMELVAARLDVDLGPVGGSSTRGPHRERLRARSRTNKFLIHSYLRGGGGVLAEALNLHADDLFFLYQPLYKLQEEGPEYGTEVLSTKKAPQALKWLNHAYNCTFEGHEDMIHAPYLWKSHSIRNTFRKKCQAKKMWITQCLQEACSDRQLRAIFTIRLGIDHISELIKLYGEEFKVVVVIRDPRAILSARRRENLGPTLNTPLTFRQQAALLCSSMAADITLANELTDRYPGSVMILHYEHLLTEPLEVLTHLYDFLGLNATSSHLNKVIRILKLDRQQEVLIQVLKAWQVELTLRESRSVDYGCSHTYEKLGYFPVPKAITNKDNYFVSWDQARMKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QTN3</accession>
    <name>A0A3R7QTN3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003374</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001457">
        <property type="protein sequence ID" value="ROT77915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QTN3"/>
    <dbReference type="OrthoDB" id="6355323at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="3">
        <location>
            <begin position="300"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1058" mass="119885" checksum="C36ECB8BB5145F45" modified="2019-04-10" version="1">MATPQRPPRATTQLTRHTVNGFRYQVAMITKGRAVFVQAVEWLYQGGPCVKTHFLSLGNSRASFKQKFNSEQRHLLENGAPFRQYDISLLYIILQLMCGLARSSDPAWTSPPAGQPLEHLLYKVKQKRNNIAHTNDVQQMSDQRLTKELRKLGRLFSRILRLAGIRRGIRPHVFRDEIWGIKQDFRDLLRKVREPLQATDLGELPQLQQEIRNFQDILRQNVQQESRQELFAFYPHLWDVTLAQWLYPDLKIQPSLNFTNLVIVEDTSTLSPSQEQKHQPSDISHENLLQVKQRNGRLPEVIIISGEGGIGKTTLLKHMLEMWVRDPSQIEGLQDVSPLLYLQLRGCTISSWNDLLKHLLHNTFQGSGLTTDIFADLFQTMQVVILLDGYDEVSKKAKKLITDLLNNCGTTRIVVTTRPGCAKELTQIMKSKKNVMNVEIKGIRREDRPYFIENTLGAFVQCPIHRTSLKDRIVRILENMDFEKDGLDVPLTLILLIIREVVAPDQSSQDIFEDLTRLMAGKVEERLAVKGIDDVEDRVKEYHEFQKKVALRGLKRQEHDLLSETVEDLKEKCTALNLPYKEMLSGFLVSKKSRQGLFIVSFWSFPHNRFQEHWAAGYVVTQLLKMSRSLPDLSGLLDSSCLPDFKNKSYLQHFNRVNNIQLDFPENPILEIYADDANEARQLAYSAITKPRSDGLMEVLADITRTLALSQKNLLDKVATAIISLVLYSNVNYLETANTSQRYYQMIMASGQHAGIVKASARVLSEVKRLETKETSLRGVLPILDHLKTGCVRVYFLQDTPNLPSNKVLSALKDLAKKDVEIHLKCLMKPSAFSELCLEAVTGPGRHSRLTRFEGYLTGKGMRLLPESLEELLTRSDAEGMRALQARLPHLPNLQSLDFGGRLTAAEIPLLPTVLEELILTTDGEGLKALATRLPRLKKLRFLCFEGRLEDAEMPLLPRGLRMAWVETDGQGLRALAGRLPELKSLYDLDIRLLECPSAASLPLLPYEGSNLTLDLRALAPLPLPWVCDVVCALCSARRRSTRLLLPSACGASGLCVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7R0K9</accession>
    <name>A0A3R7R0K9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA methyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011833</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000025">
        <property type="protein sequence ID" value="ROT86061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7R0K9"/>
    <dbReference type="STRING" id="6689.A0A3R7R0K9"/>
    <dbReference type="OrthoDB" id="414133at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT86061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="43412" checksum="26C95BB89EDC3752" modified="2019-04-10" version="1">MQLLRGERLRKGVGAGRRAENEPESRRLQNRPITTPYSNGDRLANWCRQERWRRSRPGNAIDLRSLSGRKQEQNFDKLRRIPSRTMGQPLRLLELYSGIGGMHAAVRESGIPFEVTSSFEINTSALEVYRHNFPGTSKPRNIMGLTVEEMEQLSPNIIMMSPPCQPFTRQGLKRDVEDARTSSFLHFLGLLEEITAPPEMILLENVAGFEVSQARGRLIGVLEKRGYTWQEFLLSPTEVGVPNSRLRYYLLAKLKPSTFCFPQSQEVLNELPLCLCCKTQEKVPSRESLCRDCNKQILPSLQHLLHKFHSSQNADCLQTSTSFRDIEPSLTGMLIMWRELGRLCNTTLTFLCQRFTHRFRTYHQMTLNELGYCRVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SH20</accession>
    <name>A0A3R7SH20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004464">
        <property type="protein sequence ID" value="ROT60964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SH20"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="569" mass="60983" checksum="2A42CCC62938DBD1" modified="2019-04-10" version="1">MNHKTSSSSTSLKLLPSSLSYSSLFLLLLFPSLPLLIYLLSPLLSLLTPGPLPSFLLFPLPLLLPSSLLPLPSHFSFFPLLSLSPLLSPSPSPLPFLSPSPLPLSLLLLLPLPSHLSFSSSSLSPFPSHFSFFPPPLPLPSSPSSSVSSLPLPPPLLSPLPPLSPLLLPPSSSPSSPLPLPLSLLSPPPLSLSPLISPSSPSSPPPLSLLPPPIRITTTSSDTSDYHSKQAISILMNSSWLQSILPPPSCSHHLHITFPYLYITSFFSIHFYPFFLNFLFSLLPLLKNIVHNNLPVSASLFYSLLSLLHPFLPPLPPILLFSLTRPSNPFSFLLLPFPPFFPSTSPPFSILSPSPSLSFFPSLLCPLSPLLLVYTPSLPPLHITFFPSHPSLPSTFLSAPPPPPSPFCLPLPPSSHPLSPSSSPTHPLSPIFPPPLLHPNPLLHLHSFSPPFPLLSLFSLLLSFLSPSPSSSPFSPSLPPPLLSLLPPLFSLLHPLLFLPPSPPLLLSLLSLLSLPPPLFPSLSPLLSFRSLLLSFLSLPLPPPLLSLLSLPPSPSSSLPPIVPNTAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRZ1</accession>
    <name>A0A3R7SRZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002160">
        <property type="protein sequence ID" value="ROT72414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SRZ1"/>
    <dbReference type="STRING" id="6689.A0A3R7SRZ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="40596" checksum="2E16B781C4B3F196" modified="2019-04-10" version="1">MLTHLSRHHRPPSHATTPPLTPPSPPPLTPRITPLSPPSPPLTPPSPPPLSHATIAPPSHANHRPPPSHATIAPLSRHHPPPLTPPSPPPPSHANHRPPPSHATIAPPLSRHHRPPPFSRHHRPPPSHATITPPPLSRHHRPPPLLTPPSPPPLTPPSPPPLTPPSPPPLSRHHRPPSHATIAPPSHATIAPPSHATTQPPPLSRHHRPPPSHATIAPPPISATIAPLSRHHRPPLSRPSPPPISPPSPPLTPPSPPPLNPTIAPTSHATIAPPLSRTIAPPPLTPPSPPPPLTPPSPPPLTPPSRPPSPPPISRHHHPLPHPSLRKQPHRQEQNLRASVQPRRRADGGVLGSDAANEAANEAANPRGRSTGESVRTDDSKQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWD0</accession>
    <name>A0A3R7SWD0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001384">
        <property type="protein sequence ID" value="ROT78420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWD0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="43535" checksum="1EDBCABA7BFE4461" modified="2019-04-10" version="1">MSLSTSTFSSFHCLSMSLSTSTFSSCPLSVYVSPLPLSPHSTVCLCLSPLPLSPHSTSVYVSLPLPLSPHPLSVLCLSPLPLSSSFHCLSMSLSTSTFSSFHCLSMSLSTFSSFHCLSMSSLHFPLSPHSTVCLCLSPLSTFSHSNCLSIVSSPLPLSPHSTVGLCLSPLLHFLPHSLSSLFSSTSTSFPHSTVCLCLSPLPLSPHLHCLLCLSTTSTFSSFHCLSNVSLHFHFLLIPIVCLCLSPLHVLLLLIPLVCPNCLSHTSTFSSFTVCLMSLSTSLSPHSTACLMSLSHFYFLLFCLSMSSPSTFSSFHCLLCLSPLPFSQILVCLCLSPLHFLLIPLSSMFSPLPTFSSFHCLSYVSTSTSTSLLIPLSVYSLSLPLLLIPLSVYVSLHFHFPHSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SXH7</accession>
    <name>A0A3R7SXH7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative digestive organ expansion factor-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001165">
        <property type="protein sequence ID" value="ROT80031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SXH7"/>
    <dbReference type="STRING" id="6689.A0A3R7SXH7"/>
    <dbReference type="OrthoDB" id="10264378at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="1">
        <location>
            <begin position="113"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="335" mass="38007" checksum="11861C70B155CA3D" modified="2019-04-10" version="1">MSDSVADQVKDRKKWTSKFEKWPALGRVKVEVPSVEVTVPKLLLLSDKAEADCDLNIGTVPKIPKKKDYKLQDYYVRKLLCENLPHANFDGNSSCPTSLTETQKELLAILSNYSDLYFPEATHERWEEIRTVYTLHAINHVLKTRKKVLNHNGKISKAKLEKRHEDLDCYRDQGFTRPKVLILLPFKHTAYRVVETLITLTLEGKKSIVTNHKRFKQDFGPGSEDEGELANKLNRPDDFNEIFRGDTKEDFKIGVQLTKSSVKVSATLVFEVELISIGDSPPVVNVFKQIDSDSDEHLSKEEVRAGGNGAGVCTYYPLLWISSAAVTYFIVNGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYI4</accession>
    <name>A0A3R7SYI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000968">
        <property type="protein sequence ID" value="ROT81473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYI4"/>
    <dbReference type="STRING" id="6689.A0A3R7SYI4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="40649" checksum="2EEC55FCC4A55CD4" modified="2019-04-10" version="1">MAFLRCCCCPRWARASWALLVSGDACLLVIPLFPCTSISSSPSLLPIPTLSFFPTPFILIFISPHISSLPKHTLPHFPPLPLAPSTSQPAILLPLPSSLLHFPPFPSLPPSPVSPSLPPPLPISPSLPLPHFSPLRPFPSPFLPPSPSPSSPPISPPSPSPISPPLPLPFLLPFPSPSLPSPIFSSPSLPPFLLPSPSPISPPLPLPHFSSPSSSSILLPSPSPSPISPPFPFSLPTPISPPLPLPPLPISPPLPLVPSPSPHSPPPSPFSSLPSPSPQFPPPPHFSSPSPPLPISPPSPSPISSPFLPHSSPLPLPLPLPPFLLPFPSPSSPPFLPPSPSSISPPLPLPLPPSHPLRMPPGPSPAGGKPRFLPPSGCDDDSPGEPPWPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYN5</accession>
    <name>A0A3R7SYN5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Neurofilament triplet H protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024944</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000906">
        <property type="protein sequence ID" value="ROT81896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYN5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="700" mass="78386" checksum="4E11EE909B803CA4" modified="2019-04-10" version="1">MPHIHVSCRHPRVMSLRCHSAITVYMSHPRVVSRVMSHPRVLSIHVSCHIHVSCRIHVSVSIHVSMSTSTVSCRIHVSCLLHHVSCWHPRVLVASTCLVASTVSCRQSTCLVMHLHVVHGVHVTRTYSCRVMSSTYQCHIHGWFSVHGVMSASMHPLSMSGMCQSTCHVASRVNCRVSCRQSTCHVASTCLSCHVAIHVSCRIHVLCCTHVSCSIHVSCPPSTHPLMSCHPRVLLHPHVSCLHHTCHLHPCITCHVASTCLVHPRVMSQSTCHVASSSTCHVASTCHVASTCHVASTCHVHHVSCASTCHVAFHVSCRIHVSCRIHVSCRIHPVSIMSHPRVMSHPRVMSHPRVMSHPRVMSHPRVMSHPRVMSRVMCIHVSHPRVMCRIHVSCPRVHVSVALHVSCHIHVSCIHHVASCHVASMSTLCRIHVSCASTCHVASTCHVSHPRVMSLPRVMPCHIHVSCRIHVSCCIHVSCRIHVSCRIHVSCSRVVAIHVSCRIQCHRIHVSCRIHPCRIHVSCRIHVSRVASTCHVHVSCPFHVSCRIHVSVASTCHVASQSHIHVSCRIHVSCRIHVSCHIHVSCRIHPRVMSHPRSHPRHVILLHPRVIHVSCSRVMSHHVSLFASTCHVHMHHVSCRIHCTCHVASTCVIMHPRVISRRIHVCSQCRIHVHVSCRIHVSCRIHVSFRIHVSRRIHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9N9</accession>
    <name>A0A423S9N9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative serine/threonine-protein kinase 10 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021465</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004499">
        <property type="protein sequence ID" value="ROT60887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423S9N9"/>
    <dbReference type="OrthoDB" id="10027016at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001091">
        <property type="entry name" value="STE family protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022165">
        <property type="entry name" value="PKK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051585">
        <property type="entry name" value="STE20_Ser/Thr_Kinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46538">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46538:SF3">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12474">
        <property type="entry name" value="PKK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="35"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="315"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="730"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1297"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1060"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1224"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="348"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="747"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="771"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="823"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="858"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="896"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="915"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="932"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1297"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT60887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1419" mass="160208" checksum="334A9F3A7409CDFC" modified="2019-05-08" version="1">MPLISKFKDIFKGGSSAKKKKLFHNVRLDNPEDFWDIVGELGDGAYGKVYKAIHKETKQYAALKQVVLEAEEDLETFMIEIDILSECKHENIVELLEAYHFDGKLWMYLEYCDGGAMDSIMVDLDRPLTEPQIAYVCKYLCRALVYIHSNKVIHRDLKAGNVLLTMDGGVKLADFGVSAKNKNTYDKRGTFIGTPYWLAPEVILCETFIDAKYDYKADVWSLGISLIEFAQMDPPNHEVSPVRVMLKIQKSEPPKLDYPSRYSKEFNDFIAKCLTKDPALRPSATELLKHPFIDREVDVKYIRDLLLEYKAEVVEEDVEEDADRTSRHSQDDSSQDYTFPIISANTTKDQETNNKERIEEEKPPSPRKEEKEVVPPVPGERRLSKGPAPSPPVTGSPASTPTSSASSTPSKKGPAPAVPASTISSKPRAPSPVDAPSDGLVADPVVSTPINTSKQVTSTPSGKGPAPKPAPICESPVPKEKPPPTVSMADIPDQKLVSEKAEKPAETIIASIGSEGTVIVRTPTPTPPEPTQSQPVKKESIVTYSGPAIVDEGLQEGGEQQPSVDMIDTISHTPPPLSPSLSEAEEQAVRILESAIESAVETASNRSSQDEGEEANVTLAGTSVILTPDHVEEEESTVLVSAVQDKDEGVVEVQVITNDGHKLDESEVVISNSSILTNDADSQPEAASKSRYEITLEEVDDVGVATRAKNVNDTTHISVVAVDDLAEAAELPKQTPTKAQEAPTWPVSEQQTNTTSKLPSQNENDNHGHLETSSNISNMSNLSAGTPSTGRSVSSAEEENRPTMSLLIEGTTVGATDVDDDVFDHSEHNESKTPKDNQTRPVLIRESTVESEVSIESGFSTGSTLSTPTHQNIPARNNTTVAGSPGLKILPNGIGKDNHKLSEKSDWDNVSTASSEKENKPREREEEPAEEVVLRRPPAGDKQDVALKPVDKNRENRAARTKEENDLVALRKKTRKRTRKFVIDGVVVTTTTSKVIYGDDEDGTLSSGHLARKQELRELKILQKQEQKQFQELAVKANFAKIEQEKKFEAEKQQLLRGYDTEVEALNRQQKQQVEKAEAQQEIELKNASKKIRAEQERELKAFRESLKTELKLLKQEIDLLPKDKRKEAFKTRKERLDHEQSEREKTFLERLNEAHEMSLKRLGDDHRERIALLERQFLQQKHQLLRSRESALWEMEERHLHEKHQLAKRQLKDIFFLQRHQMLLRHEKELEQVKRVNQQKEEELIKRQQIEKRQLPKRIRQEMKARELMFRESMRISTTHLPDSHDDEKDKIRKFQENEKRRYEAEKRRAEQKHKHKLEELQAASEYAIKELEQLQNEKRKMLMEHETYKLKSQDEEYQREVREWKENLKPRKQKLEEEFEKQLNEQEQFYGAYLCRGLSASVTPSQSTSSLARSNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBN8</accession>
    <name>A0A423SBN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004062">
        <property type="protein sequence ID" value="ROT61638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBN8"/>
    <dbReference type="OrthoDB" id="6367319at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019021713" evidence="2">
        <location>
            <begin position="25"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="48768" checksum="FC2A6D6815E867BF" modified="2019-05-08" version="1">MFGRKKFLGMNVKVVAALAVVAVGSPVPDNCLVPCGTVGQTYVALPLQYQASYAVGAGPVAPTPEVQQATAAFMAAWNAAAARANTITSTLLTPSGYVQNPAQVQTACAQFLAAWNQAATRAATVQHAVYSLPQPVQQTEEVRKATEEFMAAWRAAAQRVSTIQQAITVSADPYSSAPKPVEATEEVKRATAEFMEAWNKAAARVPSIQTTMYQLSGTTPSATPAQPAGSTPQFAPSLTSQTPAQSIGTYSAPSSFTPAAPPVPSHGAPRPVEPTPEVQRATAEFMAAWNKAAARATKIQSVLVKSGTPGHYNIQVPQQVQATREVQKATAEFMAAWNEAARQATTVQHAMYSVPQPVQPTEEVRRATAEFMAAWEAAAQRASAIRQAVSVTADPYSAAPKQVEATEEVKRATAEFMDAWNKAAARVGAIQTTVYQVAGTVPAAGPAQLSGSAPRFTPAVNSNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCS0</accession>
    <name>A0A423SCS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020207</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003900">
        <property type="protein sequence ID" value="ROT61974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCS0"/>
    <dbReference type="OrthoDB" id="6376806at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159">
        <property type="entry name" value="CENTROSOMAL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23159:SF31">
        <property type="entry name" value="CENTROSOME-ASSOCIATED PROTEIN CEP250 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="733"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="436"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="534"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="733"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="746"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="862" mass="97176" checksum="75BB428887A55B9C" modified="2019-05-08" version="1">MSSSFELKGQQCYAEIRSCTNISEALQARTGLNDNQIQEQQEASAQLEAKRKQMEERIRQAGTTKQQLQDQLLQLQTEELQLKNEEVQAKTENLEAKSALQKAEGEKAQLNNEISLLTQELHLAKEQNKQIETQISFIRQKVTQSTRTKNELTQGKDTKAAMKSSFSQNLKEEETLIKRLSDENSRLEEDIENTRGSGENLTKTKAELEQKVNALNIQKGELEKGIQRAGESEKTRIPESSVTRCRRRVRGASAAAWVGEVDLVYLECELPSRFFFLIFVDGKCTEGRRKYDRRRRTHAPAPCLYKAAATSSLHSSRRSVRNFRNSRTLSFAPSKDMLGLALLSLCAVGWASAAPHDEDLRTSVVFNQLAIAQLLDNVSNISRVTTQLAQLSRSHTAQTQQLSEGSDVTPEQDESSPGTFIPSDFVEKVKARENKLQELLQMNNQTATVIQQLEEQSLQLQNEVDLRRQEAQQKEDSIGQLEASIRRVKDDTLQLLAKGSDTEAEKASLQAKTQALKDQVAAEKALRPQKQATKSQLDQQVAELESNSKEIRQQMARLDQELEQLEQRKATAEGEKRAQLGRNADLKEAKEDALAAETRIQTGIDQLTGRIRKIRSCTNISEALQARTGLNDNQIQEQQEASAQLEAKRKQMEERIRQAGTTKQQLQDQLLQLQTEELQLKNEEVQAKTENLEAKSALQKAEGEKAQLNNEISLLTQELHLAKEQNKQIETQISSARQKVTQSTRTKNELTQNRDTKAAMKSSLSQNLKEEETLIKRLSDENSRLEEDIERTRGTVANLTRAKAELEEKLNALNIQKEELKKGIQRAGESEKSVQASIARVSQEIQEIESEIEGMATQLGQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCV9</accession>
    <name>A0A423SCV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003877">
        <property type="protein sequence ID" value="ROT62004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCV9"/>
    <dbReference type="STRING" id="6689.A0A423SCV9"/>
    <dbReference type="OrthoDB" id="47007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43975:SF5">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43975">
        <property type="entry name" value="ZGC:101858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="101" mass="10868" checksum="39E7D283BD5E6EDD" modified="2019-05-08" version="1">MSKAAVDQLTRSVALEVAERGVRVNAVNPGVIVTEVHKRGGMSEEDYKKFLEHGKTTHAMGRVGEVEEVSRAVVFLASDNASFITGVTLPIDGGRSIMCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SD96</accession>
    <name>A0A423SD96_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_020028</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003811">
        <property type="protein sequence ID" value="ROT62140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SD96"/>
    <dbReference type="STRING" id="6689.A0A423SD96"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001817">
        <property type="term" value="P:regulation of cytokine production"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002682">
        <property type="term" value="P:regulation of immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001370">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF23">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019495309" description="C2H2-type domain-containing protein" evidence="13">
        <location>
            <begin position="21"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="335"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="368"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="423"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="451"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="193"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="560"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT62140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="730" mass="79780" checksum="7E9ED75D307A0464" modified="2019-05-08" version="1">MPVVRVPGGLAMGALEVVWAVWCGCRGRSDLTQAGADSCCVFQTGPAQRGDFHLLRGAVPPSPAPQPPTRRVVTVPASFRKCPHCPTIFMDVAQLAAHLAAQHRDQQRERDCQRCRRRFLTYEDNTACDPCLMTLRQSALPSRKGSGAAAGSAAAECVCGHCRQTFPSRVLAELHCLSTGHDLAQIGSAEEMKVKEEGSSRVAGNAGATGKAKEEPRGAGAPPPSASEARKWAGKAKASRKRRLTRRNQTTCEVCAKECGSVSSLYTHLRTAHPAMFPYECGVCGRRFSLEASARDHERRHAVGELQCPACPLRFTRMSHLHHHARQLHPDFTEYPCQYCGAVTPTVDALHSHIKVHHGDRLGLPADFTCEVCKESFHTGKALATHRSSRHPGTAECGFCGAHVGSRYLKKHINAVHTKEKTHRCHECGQDFYSRTSLTGHHKRHHAPRKHLCEQCGKGYVNNVELQRHLKAHRNQRDFKCDVCGRSFLKAVDLTYHRRSHTGERPHQCMLCQESFIRPLGLRKHMLKHTAARKGKRLKYSKKKIDELTSSVICHDASPQEAEAHTPADVGGLGAGEVAPGSDQPPQHAPPSDLPQTLQVFPSPSSLAASSLAQPQPRLQTTLQQLTPSTLQVQQLAVTDLDGSQLEGQLELSQVVEDLSSGELLGMGPDLLLEATDVRGDDDVEGAMGEGGHGKRAAGEQAAQPVQVIYVQFVEDATGWRPEQQLQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFG0</accession>
    <name>A0A423SFG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_019221</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003524">
        <property type="protein sequence ID" value="ROT62928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFG0"/>
    <dbReference type="STRING" id="6689.A0A423SFG0"/>
    <dbReference type="OrthoDB" id="6379141at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000164">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF444">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="9">
        <location>
            <begin position="206"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="387"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT62928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="45211" checksum="267610E60C6AEFC3" modified="2019-05-08" version="1">MRSLFLKRLPADIQQILLVSDAPLEHLALKADAMLAPRAPTPSKATVSAATTTSAVTLGSLAAQVATLSGWAEVSLLPASHRDKRFPSSRTLEAANTSPINTYGERSRILSLEGEPAQRFQWIFLVADVPQPIIGADFLAHYGLTVDLQEHPAGIPGLDQADQPGHPTTARSPAPHRHPRSPCPLSLPSARPDRCRSARAEFDHMMQLGIIRPSSSQWAAPLHLVKKKDGDWRPCGDYRHLNTITAPDRYPLPHLHSFSHELSGCTVFSRIDLVRAFHQIPIAEEDIPKTAVITPFGLFEFLRMPFGLRNAAQTFQRFINDVTRGLEGVFAYIDDILVASISEADHARHLRALFGRLQDAGVVINPGKCQFGVASLSFLGHTVTPKASPAGEGHRYKEVPQASDGEAAAEIPGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SG07</accession>
    <name>A0A423SG07_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_018922</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATPase d subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003476">
        <property type="protein sequence ID" value="ROT63168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SG07"/>
    <dbReference type="STRING" id="6689.A0A423SG07"/>
    <dbReference type="OrthoDB" id="35799at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005514">
        <property type="entry name" value="ATPase_F0_D_mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT63168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="171" mass="19007" checksum="4D2BF4C019FD5136" modified="2019-05-08" version="1">MAARRIASSSIDWAAFASRVPAGQKNMFNAFKGKSDAYLRKVITLPESVPAINFAEYKARIPVAGMVDTFQKEYEALKVPYPADTVSQQIADVESAAAAEVQAFIKGSEARIAKLTEELGHWEAMIPYDQMTMEEWAEAFPEQAISMEKPTMWPHHPEDQPGYVAKEGAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIT3</accession>
    <name>A0A423SIT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin repeat domain-containing protein 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003325">
        <property type="protein sequence ID" value="ROT64112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIT3"/>
    <dbReference type="STRING" id="6689.A0A423SIT3"/>
    <dbReference type="OrthoDB" id="6370481at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="203"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="268"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="401"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="333"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="47287" checksum="A8D549FCCA5D6717" modified="2019-05-08" version="1">MSSPSPPTHPPKPIVLPPFPPPPTPSPTTHNPKATPPILTHRTHPHHATTYAPPSPPLNQPTTQLLPPAPPTPPTLTTNHVNSTPPNQPTNPMILLPPHSNTNTACPTPQITNNPSPTLKSTASRTKLENLKTRNRFAFQKQAREAARAGDVRRVREVLRRGFGIETEFQEAANRGPERSSGHSALVALLMQENAHVNASTKDGMTPLHLASWGGHAEVIGVLLAKRADGNAKTTEGMTAIHLAGMGGHVSSMEALTPACDILSVTREGKSALHLAAEYGNLGAVQWLLLQGLDASIRDKKGWTPRQYAKDEGHRKVVEVLEKLEKQRLPQGFAQQQKIVKDLQEKLQARETEINRLNRQQAMKDRIQERAQAQIKNELQEMRETLRAQSEMIVRLQSTMLTKAEPGKETQVGLRNGPGDGNEDNWSPSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKW4</accession>
    <name>A0A423SKW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidase M12B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_017231</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKW4"/>
    <dbReference type="OrthoDB" id="6365097at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF281">
        <property type="entry name" value="PAPILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19030">
        <property type="entry name" value="TSP1_ADAMTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12B" evidence="12">
        <location>
            <begin position="84"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="376"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="510"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="625"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="708"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="740"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="516"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="631"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1023" mass="110932" checksum="FDA08EBE81D207F2" modified="2019-05-08" version="1">MTLVSPVTPPFSLPTGTQVPPPCNTYLSSELPQENRGQINQEQVPSEPEARFESPIGHIDFNVDFAHKMKNSSEQNKTDDAETRVLRLAVFSDDALLSHLSDMHPEDPLSATHSYVTAGVSAIEQVIQQAMGKGVEFKIKLVQVGVWAEKGATPFNTNGLSSSNLLNFCEWASERKPGRGDPGYWHHAMMLTGKELFETTKDSLGVTFVGGLCHPRTSCSVVEANSFKAVQVAAHELAHSMGVPHDGEGAAARCPSEGFIMGQSLSEETFDWSNCSRDAISAFLKNETCLERGAASSRATPKELDHTKGGPPGQRYPADAQCQLAHGKGFRATPSKRNLCQYLMCTNGVTTRGAHPALPGTTCGANRICVAGDCKEGKIPPTKPPTKPPTKPPTKPPTKPPGNGGGDSVFPPAKIPNEIQYIPIPQRCYFLPPFLHPYIGCKSPPTGPSNPNRPQRPNRPENPNRPQSPAKEPQPFRIGISALPEVINNRSFSEDNYTRILVNDEPVETTADVKTTKTISSKSESTGATTTSAEFAEATTFEPESPKTTVSSDESWQVFNDEAPIPEGNSQETTTFTIKSLENTTAESSQIPTTEAKLPDDEFVLFDAVNEAVGSLAGEIRSLTEEEEQLQDDKENGEKVFDGKDLGGADQNATDTETKSDIVAANRTTETHEPTEEVTATPYTTETITTQTTTDSFVREEMTTSPLPYEAKNTTQGHTNHSRSEQPVTLRLTADDAHQLEDISRREVGNQTTTTETPTSPVDEKQLGKNNEDEEEHSATFSVDNFTIAGSGLHFSLPSHLLQNLLAPLLMNSHGTGAPMMKAEDPLVSRRQSEENFHRHDSAHPRISYLRDGYRQEPLLAATAPVHTRAFRISPCTRACGGGTRRVAQVCVETSAPDVVVSQDFCNGLPNIVAPFNQSCNTFPCAVPEWVVGPWSPCSHWCGLGLQRRLVACGMSLVEGASPLGAGRFVAAGKCSGDQPLDVKLCKGSCIQVDCKLPSNRLHPACYHLLGETPIERDHRPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLT1</accession>
    <name>A0A423SLT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016848</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003122">
        <property type="protein sequence ID" value="ROT65197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLT1"/>
    <dbReference type="STRING" id="6689.A0A423SLT1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF189">
        <property type="entry name" value="CYTOCHROME P450 4C3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="308" mass="35652" checksum="AF84CFB71ADD91C3" modified="2019-05-08" version="1">MTSYLLSRKIGSLVQQRQARPWLQPDLFFKLSGYQKEHDACLKVLHDFSNDTIRSRRFEYLEGKKNKDQNTTEDEAIGKKKRLAFLDLLLEYSETVSRLSNEDIREEVDTFMFEGHDTTAAAINWSLYLIGSNPEIQARVHEELDSIFGGSDRPITMADLREMKLTENCIKEALRLFPSVPFLARELKEDAVIDDYRIPTGTTVTVVTYCLHRDPEQFPNPEVFDPDRFLPENCKSRHPYAYVPFSAGPRNCIGQKFALMEEKILLSHILRSFRVESTVKREDLRLIGELVLRPENGNPVKLLPREAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNK3</accession>
    <name>A0A423SNK3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003031">
        <property type="protein sequence ID" value="ROT65828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNK3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="50144" checksum="EA89CD339699EC8A" modified="2019-05-08" version="1">MARSRASYLLSVVMARLVRLLLTNTVVWGSKPPRSSPSFNPETHTRSSFFPPLSFLFTPLSFFFFPLFSLLFFPYFSFLFFTPLSFFFFPLFSLLFFPPLSLIFFPPLSLIFFPPLSFLFFTPLSFFFFPPFFFSSFVPLFLLFLFFPYFFFHFFPYFFFHFFPYFSFLFFPYFSLLFPPLSFLFFPPLTLIFFPPHSLIFFSPLSLIFFPPLSFIFFPPLPLIFFPPLTLIFFPPLPLIFFPPLPLIFLPPLSLVFFPPHSFLFFTPLSFFFFPPLSLIFFSPLSLSFFPPLSFLFFSLSFFSHLPSLFFFSFSSLFFFSFLPLFFSSFVPLFLFFSLLSSPFFSILFSSFLFFPPLSFLFFTPLSFFFFPPLPLILFPPLSFIFFPPLPLIFFPPLSLLFFPPLSFLFFSLSFFLIFPPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRU6</accession>
    <name>A0A423SRU6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase Rpb4/RPC9 core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_015035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002878">
        <property type="protein sequence ID" value="ROT66909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRU6"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030880">
        <property type="term" value="C:RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="5">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT66909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12728" checksum="247E1B43CF066CE7" modified="2019-05-08" version="1">MSEPQNSNEATEEDATELQFPKEFEKAETLLISEVHMLFSKFKNRATIKAIRELLNQKKLHKFELAALANLCPETPEEAKALIPSLEGRFEDEELRVLLEDMATQRSFQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRY0</accession>
    <name>A0A423SRY0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein bric-a-brac 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014958</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002871">
        <property type="protein sequence ID" value="ROT66958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRY0"/>
    <dbReference type="STRING" id="6689.A0A423SRY0"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000019">
        <property type="entry name" value="Ligand-dependent corepressor isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05225">
        <property type="entry name" value="HTH_psq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50960">
        <property type="entry name" value="HTH_PSQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH psq-type" evidence="6">
        <location>
            <begin position="93"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="140"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT66958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="277" mass="30821" checksum="0BC8C5C0F850366B" modified="2019-05-08" version="1">MPLPGLLSSHVPHLLPHDHRDHLESPYSLSLKKEQHDEESRSMSDISREDEQEKSKIESLANGPLLPEFNPYHIDPNGPSHYSNFVSYVPTPKPEWKRYKQYTKTDLMDAIEAVRSGMTALQASRKYKVPSRTLYDKIKKMGISTVPRRMPSKKPSPSSTDLETSTADTHAPPEHHDPPPRDARDARDPPLPDHDKRHHKSATSDDDDHSASGAPVVIDDEDESSSPTPGSTPALGSFSLVGRKMYENGAGESSAKPLDLTDTESLLPKRAEIEERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUW2</accession>
    <name>A0A423SUW2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013899</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002732">
        <property type="protein sequence ID" value="ROT67991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUW2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="532" mass="58235" checksum="1B7FB2145D85B681" modified="2019-05-08" version="1">MLHQSLYTHQGASAKRVGVCSGSQSERSGRSLVSFSACRSLSLSSRITTTNRPNLSLATAEVEARQDSLAHPCSASHQTSENRVRESSSRESETGARGRPAIEENLPYSRTHPPLLDTRGARRFRLDLSLRPGSSPRGESTALHSLGEKSRLPAILSHSLSVANTNCRLSERCRKSEGGRSWPGADTKGGKGNSGVAGQDRGSALSRWAGAYTILLSLLFFRLSLFPYLQRSLRSLLRLTFLSSHRSSLGLFIILLTSYSPSFIISLSHPSIERLSLRVSRSLLSLRSAPCSSPISSASPSFFSRSLRSLTPNLYRYPPSRSHAILQKQPRKSYTLSRPLSLTDQFTPHPSRTTSHPVHLLLFSSTSSAKYSSHHLLPLSPSGILSLRSALSSARRLIESRRISLSSLSVDLYDVRSSYSPPSRLARPLSIRLSDPAFSMPGLLSFSALLTPLSLSLSLLFSNRRGRPFYLSDSRPPVSAHSLRLVSPLPRLGISLSVRKPPFWLCSSVLMELASLSSVCGRQHPRTSLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXQ7</accession>
    <name>A0A423SXQ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012824</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT68969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXQ7"/>
    <dbReference type="STRING" id="6689.A0A423SXQ7"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000103">
        <property type="entry name" value="Histone H2A type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="12">
        <location>
            <begin position="11"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT68969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="15540" checksum="779FBED8587FBB76" modified="2019-05-08" version="1">MSGRGKGGKVKGKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPVTCSWPSVTTKSSTSSSLALPSPRVVSCPTSRLCSSPRRPRRSKYFPYYLFSTTSAPFGATKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYK0</accession>
    <name>A0A423SYK0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative thioredoxin domain-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002569">
        <property type="protein sequence ID" value="ROT69360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SYK0"/>
    <dbReference type="STRING" id="6689.A0A423SYK0"/>
    <dbReference type="OrthoDB" id="6341258at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052792">
        <property type="entry name" value="Thioredoxin_dom-contain_11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46497">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46497:SF1">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="320" mass="35544" checksum="2D96DCE77579971B" modified="2019-05-08" version="1">MDAPLSKAALAAFVLNYTSGSLDRTMLSGGSERASRCEEGQVCIRELTSRDYVEVTQEPGKMVVVLHYSRNCAACTTVGHVLMAVAQVARHLPNITFARINVATNTLPWNLHFDALPTIIVHPHVHKSESRIFDLSQQLTPANLMSFLVSSLGPGHRLALALSVCRDQCQEQVLRAARLATTQLHHSLTSNTTRLLQVSERITSLTKGAVGSKGKESLHEDAHYRVLMQAKKLIVRDIKWQRMKLTYLREIQRLFSVGLEEGKEGEDEGERLLPIEGDPKYQGDLLRTLNSLMRKGSSVPKDITSLSGQEPSHEPPHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T034</accession>
    <name>A0A423T034_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002512">
        <property type="protein sequence ID" value="ROT69847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T034"/>
    <dbReference type="OrthoDB" id="10065127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="49"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="50992" checksum="10B70D24C2F41B4E" modified="2019-05-08" version="1">MAIRPYFAYQASLIPFSFCRQESFARWIPVCSHSEPPPNYSHDLLPETNFTCSDKATGGYYADPEAGCQMFHVCVRVSDEEIRDFKFLCPNDTVFDQQNFICANWRDIDCKRSTRYYSKNDLFRVDESTTEEEYETESTASVFYEDTFDTGSGGRKGKSQDGDAAQSRTPCPRPRQAAPRPRTRREAPSSPGRLETFLADDHADEDNLFHGVSDPFASYDWRRDSSGVTGVHEDDVREQRFGTGPRCRAPAPLLFSPASRNQEFTSTHRQEQGNPSRARAHHGEGAGRGRVDGPAARAALSSARGASRYSSVGRSARGAPAPPRPTPPAASSPLPLLQDRLEKNAGRRHTTALRPPPRAPGCGPRGSSRPGPPPGTPGTRCSAEGGGARMRSPAPRTSADQSIEACDVRDTTEVMVTECAMKGGALASPWKEEAEMLVIFTVARSRCRTLGLLVFLPREDQGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0Q5</accession>
    <name>A0A423T0Q5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002482">
        <property type="protein sequence ID" value="ROT70037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0Q5"/>
    <dbReference type="STRING" id="6689.A0A423T0Q5"/>
    <dbReference type="OrthoDB" id="6343208at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="524" mass="56284" checksum="742E174F29CB7336" modified="2019-05-08" version="1">MAVADPTEPHPPPARANTPLPGRPCVFYAPVPNPQTLRTHPPTCLWPPTCLRELASSDAVPTYPLSLPWPPTCHGTRPSALPPIPHRLRSLAPPQACLDGLGDSISRALVLVPLFTHPSLFSPLSSLRFPSLSLSCPPPLVPTLTPITIFYPCYFSPLRLLPLSGSPALPSSSLPFSPLPPLHQLPQVTPPPFPSPPSVLPLPPAALHFPLFAPTPLPLPPFYPSPPPPLSSSSSLPPPYPYSLPFFSPFPPLLPPFLPHTLTPYPLPPSPLPPSSPLPLSSPLLPLPPHPALSPLHPSSPPNPSSPPPCSSPLPTPLLPPPPSSPSPPTPLVCQAPATEVLAGTMAFIASADNDEEQAPASSGASVKARLIKRGRITATAGGVPQRASVSVKRPLDLVLPCQEIQYLDISYQKVGTVTHILPQVQFSPIPRKKIAYHPVLHNSIHYCDVPYCGTGERPVKRKPLQRSHSIAVADLRERVDCEWTSSYKLRSLWFAEELPSHRFTNRGLITLPANQRNPPSPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T278</accession>
    <name>A0A423T278_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="3">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_011189</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002414">
        <property type="protein sequence ID" value="ROT70513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T278"/>
    <dbReference type="SMR" id="A0A423T278"/>
    <dbReference type="STRING" id="6689.A0A423T278"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000101">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT70513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="16904" checksum="3D1E4FB0DF580DF9" modified="2019-05-08" version="1">MTALQRIAKELEDLADNPPDYCSAGPVGNDLFHCQATIMGPRNSPYEGGLFDVAIDFPKDYPFKPPRISFKTPIYHINIDVDGDICLDILGSEWSPAISLSKVLLMIVALLNEPNPDDPLRWEAFQEYKNGKESYDRTAQMWTFMYARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6H2</accession>
    <name>A0A423T6H2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002209">
        <property type="protein sequence ID" value="ROT72082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6H2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="518"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1152" mass="127209" checksum="878C3C299AF7F137" modified="2019-05-08" version="1">MTLMLSVPPQRVKSRIRPFLSVSVSSSLPLPLSLLSSLRPSLPLSPSPSLPPFHPLSEFCQMYSRDDRKTGLLAPLTCRVTSGFVGGSLISQRSLALFDEVFLTGLFSFLHLLQPSAFSSSHLLQQSAFPLPHPLLNQSAFLPSHPSNKAPFPPSPSAPTKRLFPSITKAPFSPTPTKAPFLLPHPPNQSAFPFFPIRSNQSPFPPSPSAPTATKRLLLPIRSNQSAFSPSPSAPTKAPSPSHPLQPKRLSSFPSAPTKAPFLLPHRSNQSAFPPSHPLQQSAFPPSHRSKQRPFLLPHPLQPKRPFPPSHPLQPKRFSLLPSSTFSSIRSNQAPFPAFLRFNQSASFPIRSNKGFSPSIHSNQSAFSFLPIRSNQSAFPSFPIRSNQSAFPSFPIRSNQRPSFPRFPSHPLQPKRLSFLPLRFQPKRLSPPSETKGLSLLPIRSNQSAFPLPHPLQTLLLPKAPFSFPIRSNQAPFPPSALPPSAPTKAPFLLPHPLQPKRLSSFLAPKRLSSFPRSNQSGSFPSSSLPSLNQAHSAQQALSSFPSAPTKAPFSFPSPLQPKRLSSFPIPLHKAPFLLSPSAPTKALSSFPIRSNKAPFPLPNPLQPSAFSSSRSNQSAFSFHPLQQKRFSSSNQKALSSFPIRSNQSALFLLPSANQSAFPSFPIRSNQSAFPSFPIRSNQSAFSPIAPKAPFLLPSAPTKSAFPFLRSNKAPFPPQSAFPPSHPSKRLFLLPHPLQPKRLSSFPIRSNQSAFSFLLPNQSAFPPSHPLQPKRLSSFPSAPTKAPFPFLRSLPIRLQPKRLSSFPIPLHQSAFSPIPHIRSNQSAFSSFPSAPTKAPFPFAPPLIAPTKAPFPPPHPLQPKRLSSFPIRSNQSAFSSFPIRSNQSAFSSSPSCRPTKAPFSLPHPLQPKRLFLPIRLQLFAPTKAHLLSSFPIRSNQSAFSSFPIRSNQSAFPSFPIRSNQSAFFSFPSAPTKAPFPSYPSAPTKAPFLPHPLQPKRLFLLPHPLQPKRLFLFPIRSNQSAFPPSHPLQQSAFPLPHPLQPKRLFPSHPLQPKRFSSFPIPRLFHPLQPKRLFLLPHLLQPKRLFLLPHLLQPKRLFLLPHPLQPKRRFLAFKRLHPLAPSPLSTHNRAFLSSAPASITRQTAVLPINRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6M0</accession>
    <name>A0A423T6M0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002214">
        <property type="protein sequence ID" value="ROT72045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6M0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="48126" checksum="98DB2F3898F3A748" modified="2019-05-08" version="1">MPLSSFLCSSSSLPSPLTLPYYFFPLLYPPFRLVLHLLSLFSWFLSFLLPCFASLILFLLHYRPLSHIPFFFAFSISFFLPFALSPFSLPSLGSLFFLSLSSAFSSFSSFSSSISLFFFFLLQSSLPLPPFISLFSLSLSSSISLLLFLFFLLQPSLLLPSFISLFPSSSSCSFSSFSSSFSPPLPSPSSSSFFSSSSLLFLCLRLFPSSPFPPLPLLLFLFSAFFPLSLPPFLLFFLCLRLFPSFPFPSSSSSSFSSSFSPPLSSPSSSFFVFVYFPLPPSPPIPLSLFPLSLPPFLFFSSSSSSFSPPLPSPSSSSSFSSSSLLLLCLRLFPSSPFPSSSSSPFPLALLLFLLFFFVILLFLFLLLFFPLCLPPLPLPLFLFLHLPDPHLHPSFACPSPRSFVSSIRSFVLSVRPFVPLDRLSFVLPVRPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6P6</accession>
    <name>A0A423T6P6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002213">
        <property type="protein sequence ID" value="ROT72075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6P6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00021">
        <property type="entry name" value="PRORICH"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="61529" checksum="350C19EBAEE2B2EF" modified="2019-05-08" version="1">MPAHLAYLPLHRPRHFEPCPPPLVFPLARPPALPALPTEGAFLLPTPPVAPLLPPAFPCPPPPRCPSPCPPSATEVPLPPTPPPRVPFPPAPPTEVPSPCPPTEVPSPSPHRGALPLPSPTEVPSPFPHEVPFPLPPPSALPPALPTEVPFPLPSPTEVPSPALPHRGALPPLPTEVPFPLPSPPRCPSPSPTECPPLPPEVPFPLPSRTEVPFPLPPPHRGALPPCPPTEVPFPLPSPPRCPSPCPPHEVPFPCPPPEVPFPHPPPPRCLPLPPTEVPFPLPSPTEVPFPALPHRGALPLPPPPRCPSPALPHRGALPPALPTEVPFPPAHPTEVPSPALPHRGALPPCPSPSLRWPKFPGSNDNNKSTPTPPPTEQGGRQTEIGVSYPAPSTRKKGEKMSEIRQILLYRDKLSTPLPTHKNDNTILISTRRGHPPPPRRPRGRRPKRRPRLSRACVLFPDCPTSFSSSSPPLSPLGYRGQAVAPSPRPAPLPRRAPRIVLPRYDTRTNKFFSPRFSFERPIFKVRSRTNPLWQNNIETRMHRGRNVDETFQSSLPQVPVSESSETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6Q7</accession>
    <name>A0A423T6Q7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002207">
        <property type="protein sequence ID" value="ROT72103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6376462at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF19">
        <property type="entry name" value="OBSCURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="110"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="208"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="54967" checksum="A613799A9C0B7EB4" modified="2019-05-08" version="1">MSLFHPGLLPPLFPSSXQATKRTDLRKQNEETEMTKKTELRKTKETATRDRCTEDEQEYRRRHGAGAERVDGRDPVRESLVLQRVSRQRAGHYTATVVSQPVHLQIKYKPECQTSPTTYFIYDKPINVTCSVTSFPPVRAIQWQWNSSNDVISTEPITEEEERVSAQLTVEPIKSREDRTLTCWAVNEMGKQSRPCGFAVKVAQMPLPLSSCRLANITASSLSLTCQRPNVATAGTTLYRAEVYFDNRTLFANVTSNRPNFNVSRLDAGTSYQIKVYVSHGPVTSQPVVVSAYTSRTSRTAPGSHESSSSVGEVVGGLAVALLLLAGGVWARQYCRKQSRAKKHEPRVPSDESNPDVVPTTVEETLDLLAAGAAKTEMPILTPVYEAMNASLQEVVPKVRKSGRKCLFSVPNPGIREVYSGMRTQHKELEEYQELRVQHSDDYPDVSLQHKDSEEQYHAGRMQGQENEQQHGGKGKLYCPVDQLMQAAETVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8H4</accession>
    <name>A0A423T8H4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8H4"/>
    <dbReference type="STRING" id="6689.A0A423T8H4"/>
    <dbReference type="OrthoDB" id="6368583at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052667">
        <property type="entry name" value="E3_ubiquitin-ligase_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47156:SF10">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM-21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47156">
        <property type="entry name" value="PROTEIN CBG20824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="78"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="156"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="243" mass="27432" checksum="A0AFD110C1011292" modified="2019-05-08" version="1">MTWPTPHDTPERRAVVAVDFYHFRSRFPAITTLIGSGASKVSEARKYILVQNKRQEQHITAASPRPTLAFRLSMPRVCPVCREDYAEGLTAPVSLSCGHSFCRRCLQTLLGLTQVLKCPVCRVLHAGASLDELPDNLALMEELAPPAEEEAVEGFMKLIIMNLEDLKFTLHVKPTDNFSRVKEYLCTHYGITPDLTRLIYRGRRLQDDKTPRDYKITCGTVIQMATCYESGVSWRVQGRVCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9K5</accession>
    <name>A0A423T9K5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_008451</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the hunchback C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9K5"/>
    <dbReference type="STRING" id="6689.A0A423T9K5"/>
    <dbReference type="OrthoDB" id="6489565at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000614">
        <property type="entry name" value="Zinc finger protein 142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051967">
        <property type="entry name" value="Krueppel_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45925">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT73135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="121" mass="13285" checksum="98507632F00977D8" modified="2019-05-08" version="1">MRALPPGMQAAAGGVGVPPGAAPFHPPPVAYRQSGATTPSRERRGPPPPPPASGPSKRCYWCHLCKREFPFPSKLNEHMRTHTGEKPFACPLCPFRTSLKWNLKSHMLRHQDSLGVSRPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG10</accession>
    <name>A0A423TG10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative ubiquitin carboxyl-terminal hydrolase 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001776">
        <property type="protein sequence ID" value="ROT75402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG10"/>
    <dbReference type="STRING" id="6689.A0A423TG10"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF937">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="265"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="580" mass="66289" checksum="DAFD28671A1AB8AB" modified="2019-05-08" version="1">MYASHYFLPPTFTGRSDTPAVSTECPYRHHKDFYRDQGASSPVRELLQRRPSEEYEKGFLYGGTQTPGSSSYPGDYWPSTDPRNKQSFPDPAASPSEEDEKGFVQTHQESKILEENAVTKQQEGFEPRTACLPDSKDKEESNFDSPGGRVSKSEISSPSHQHYGADRDNISAEKRNPSMPFPASPSAEEHQFKSHEHPQATDPSQAAHQPSLLSRRPRGRSHEHPQATDPQPSRAPTKLALEASKRKSDGETYQETLHKKARKSSGLPNLGNTCYMNSVLQCLYHTTELTEFLLSEDGRSNTNAGPVTKAFTELLKRMMNNANPKFELRELKRVVGERDPEFAGSRQREAHDFLAMMQTWLSKELEEDTEDLKIKDITIPNLRPSFPVELFNGIHCSTFICERKNRVFLRKYEPFSNLTLAVTSMSSNMEDVLKRYYESQMITWTCKLCQEDHECRHDTRIYRLPRVLIVHFSRYNLSAIGTSRKAVVYCPPVLKLDSYLHSDVKRGQEYELYASCTHQGRMTGGHYIAHHMDPSGKWTLFDDSYVKHDVEANIDKAHILFYRARRMDLVTHLSELGPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIQ4</accession>
    <name>A0A423TIQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative histone-lysine N-methyltransferase PRDM7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001672">
        <property type="protein sequence ID" value="ROT76328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIQ4"/>
    <dbReference type="STRING" id="6689.A0A423TIQ4"/>
    <dbReference type="OrthoDB" id="6380639at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21549">
        <property type="entry name" value="PRDM2_PR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="210"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="579" mass="65007" checksum="4A33335E695FDFC8" modified="2019-05-08" version="1">MEVNCCCRYASKSGSVGGGRRGGHKRKAEWSAPAWARRSENYDDAPLSVDQVDVIPLWTPAKLVAGAKGTAKIMPITVDRSSGDSAAENVKPEDKGIFPGPMSHLATDTEMETVKELPAETKTLGVGSDEEGRGNSCFSGESKTRYPRRSSRRKLFYEENVTKDDDFIYCADCEEEKEGECPYHPLFLILDNPVVRDGSEKDRARLTAPWPLTVYDSKVKGAGKGVWTNAHLPAHLVFGPYEGRVLSGHPEAGKESGYGRKIRGAGTRNTCIDAVDSAVSNWMRYVNCSRSDAETNLSVFQYKGQIYYKTDSAISRGSELMCWYGDDFGKDLGLSREPSKWKSAKKDVIDRQCEWSGLVYTSKDLMRPLKVFRKHIRTYTPPTCSTRGTSSSSGSTKQSLREEAPQIPEKASHETLCSPACDEYNTECSQCDYKWYGRLRASSPRYENESLGQASKVKRKEVGHPYILTSGRKRARTDHVVQPRGEDPSMWHAMHYAISLGTYDIAYCIACHVVRVRAAWHAMHCHQLGWSPERYSIYLVVVSHSWPKLEHSTLPSSCDRLFFHRTRFPLLAYLHFISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJW8</accession>
    <name>A0A423TJW8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Sodium-coupled monocarboxylate transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_004653</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001613">
        <property type="protein sequence ID" value="ROT76754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJW8"/>
    <dbReference type="STRING" id="6689.A0A423TJW8"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051163">
        <property type="entry name" value="Sodium:Solute_Symporter_SSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985:SF40">
        <property type="entry name" value="LD47995P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42985">
        <property type="entry name" value="SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT76754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="56187" checksum="5D21C87DD8D48BAB" modified="2019-05-08" version="1">MNIFGCAVGVVLVRNVILPVVYPLRLVSLFQYIEMRFRSRLLRKYATACQLTSCYIYVGICLYAPSLALSSVTSLPTWASVLVMGVVCTFYITIGGVKAVVYTDVLQTLVMFFGVLAVVAGRVPGHRRHHPGVGGRRGRTEAGVFQRALFRKAICFAQSQRPGIHHPGRFFLCRAKPVRSGVASRLALTSIPIPSLDTSPFARHTLWSTLVVGVYMMISFLGLSQSQYQRFASVPTLAQAQMLALLFFLGLTLLWGTFYVSGLVAYAIYSDCDPLNSGKIEKADQIIPYMVSDKLGHLTGMPGLFVAAVYGGVLSSLSSEGNAIACVVWEDFLKERPYFRDISDRSATNVIKCLSSLTGLIAIGVGLLAGKLGTIYYVISLIGAVIAGPLNGLFLAGMVIPWTNAKGAWAGMTFSLALNSWMVIGRTDENTIYDISYCYNGAIGIISNLVVSSLVSCCTGPHLPGDVEARLVYAPCARLYRSLFLLVGGGGGGAVTPRSRRSDGSGSGNAAQAGLILRKNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TL46</accession>
    <name>A0A423TL46_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_004213</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001562">
        <property type="protein sequence ID" value="ROT77184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TL46"/>
    <dbReference type="OrthoDB" id="6381660at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050991">
        <property type="entry name" value="ECM_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708:SF2">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708">
        <property type="entry name" value="TENASCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="3">
        <location>
            <begin position="80"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="225" mass="24141" checksum="BCCF10DDF4EBACB5" modified="2019-05-08" version="1">MRNTNWKVNVLCGTITHVGPLASLGGGVAIHLRRLQPRNWQLHRAGPGTFLAGGGVDERARQGRGKGRCSATTDEAVPDEPSEVIVSKVTNTTAHISWTMPLHVNGAIKSWEVTLRGDTDNEETENDVEGEMMFFDATDLTPSTNYEVTVKCQTGGGLSKGTRRSFKTLNADNTGDNQPNIGLIIGLSRPSGIRQNPKQSHAKVGGLRQSPVVTSFPGSGENLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN08</accession>
    <name>A0A423TN08_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001467">
        <property type="protein sequence ID" value="ROT77833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN08"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="50955" checksum="497DD19443AC0D9E" modified="2019-05-08" version="1">MSHIPLLQMVFAPLPSMPASSLPRVRRVSRGAAPTALRLTYCIGPIAPHALLKAPVTRASPSSSFLTVTSPSSSFQPSLSPLLPFQPSASPLFFLSNRQPLPSSSFPTVSLSPLLPLSTVSLSPLLPFQPSPSASPLSSFPPSASPLFFPFNRQPLPLLPFQPSVLVPSSFLSNRQPRPLFLPFSSGLFFLSFFLQLFPLLLSFTSPLFFLPTVSLSLFFFPTVSLSPPSFLTFLSPIPFLTVSLSPSSSFLTVSFLSNRQLLPPLHSLPFLTVILSVSLSPLLPFLTVSLSTFFLSNRQPLPLLPFQPSASVLLFLTIRPLLSIRQPLSLFLFIPLSSYSLYPSIRQLYPSASVLLFLSIRHLSSSSFYRSASVFLPYSFLSVSSVFFLLSVSCPLIPLSVSLVLIPFYPSVSSALFLSIFLLSSVLRQSVIFYPSALSLYWCDSLQRPYTDILRHPCRPSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNV0</accession>
    <name>A0A423TNV0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001430">
        <property type="protein sequence ID" value="ROT78108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNV0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="115" mass="12514" checksum="357E31A88EA723AD" modified="2019-05-08" version="1">MAGNFKRLPQRPRRLLVIINPVGGRKRAHHIYARRTKATGASWSRSTPSTRASRRRGGGGGDGLVNEVVTAAPAGGGEVGVDPMTLRLPAAHGAQGRHHTRWQHGRHLPRDPRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TP10</accession>
    <name>A0A423TP10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ras-related protein Rab-8A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_003109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001420">
        <property type="protein sequence ID" value="ROT78183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TP10"/>
    <dbReference type="STRING" id="6689.A0A423TP10"/>
    <dbReference type="OrthoDB" id="10327015at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="139" mass="15489" checksum="DA7F8B2DF148FBB0" modified="2019-05-08" version="1">MARTYDNLFKVLLLGDANVGKTALLVKFASEAPTDHAFISTIGVDFKIRILQVCGRKVKLQMWDTAGQEKFHNVTSAFYRGASGILVVYDVASEKSYENIQKWLADVGKNCADNTVTMILGNNCHLKGDERQVIRSLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TS59</accession>
    <name>A0A423TS59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative Pre-mRNA-splicing factor ATP-dependent RNA helicase prp43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001994</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001263">
        <property type="protein sequence ID" value="ROT79272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TS59"/>
    <dbReference type="STRING" id="6689.A0A423TS59"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="107"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="107"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41428" checksum="7336B81E2876D471" modified="2019-05-08" version="1">MDDLVVEKLGKAVNGGENGTSGAPSQTDLLKLLASGSGGGLGGGLGGLGGLGSLAAAAQARQNGSMMRSYEALLQGPSAGRMAPQAVTLPGPTRRRKKKRRRQPDMPKKACTPFMHFCAYFKRKLMEEGKEFPQFADFGKRAGELWRNMGDEEKKKFVELSEQDRQRYIKDMKEYEERKLAEKERERELQQQREKELQVLREKELEKIQKQQREQLEQQQKQLEQHQKHQQQNPNASLMNMLNPLSPLNPLMIAAMNQTLMQTMLTNPDLMKTVYSEAARNYYIETLKNIYQNMGSSQPNGNSVPVSSSGTHGGISDHQSHLSSSPLASMGMNVNLLSLLNSGQLSAVPTSTSSSTGSSPLTKTPSTLKAPPHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWX8</accession>
    <name>A0A423TWX8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_000320</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001048">
        <property type="protein sequence ID" value="ROT80932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWX8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="642"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT80932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="854" mass="94960" checksum="69080059FA6FF722" modified="2019-05-08" version="1">MACDGRAARAVKGTMELHRRMKRAVNLLLYFVVAAAFLAVISFLVEEHQLRRKAFRVAKVADPPSPFPPVTLCPWPPFNPLRLVRLGLNTSAASSAELQKRVENLSGLGNGGVTGRTLVEEAAWRVEDVVEEVRVGGRREMYSEEEADVRWWHRSFLPVGPCLTVSSPPLASRSSLNLTIRVRPRPLNVDLCERRESDVRRSSENLCRPAEQNSNTSLWGDYMEKGFFLIFFVYLSSTDSHLQTHIANTDLGISNSHDISVEGISTHYEVTYIDDYGDAPTCFHRCVTREAETVSKCKTISDHTIDSQIHELCVTQQQLYKVALAFIVKDAIYYNCLRSCKPLRSEHRWVWKPRSSAHSLPHHISIHLSTPITTAFKEELLYPLNDLVADVGGAMGLLLGASLLDFWKSLHAGLKCLARCLVPPSFCIGSRVSQASSQLSLWAGHTALAIAACAHLGLTTMAYILQTKEVAVSLKLSKRDNGQESQTVQDLVMSHLASRPLGCRLGSKSPNQECLIRCFLDGDALIPMPLSVVDDLNECSEEHLALPRRKYLIPSYITERIKNSDKAGSCVSRCGAPGNISAGFEKMYFVVEEEPSFSPSKLICTFGGIIGFYFGISFLTLFQDINNQLKSLSITPVLCRMVSVVVKGLVVLLCVFLMTSQLSIFILSHPIDSSSSKSLLKGSNLPAVTTCAWPPISPRNLMASAGLTEEYDRMVGLDIERRHFALIPLLQSLAKEPKAMDARLLWASSAWNHSEIWTEVTFGASFSKIHECRDCPLKDSAIFGHCKTFYPNFLISESLKHFEYEVKVHLKDESITTYTAIHSQDDYPVMEPDLISLDGIVSIKVLGRACMKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYI6</accession>
    <name>A0A423TYI6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_025318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000962">
        <property type="protein sequence ID" value="ROT81514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYI6"/>
    <dbReference type="OrthoDB" id="76101at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="121" mass="14092" checksum="E84E70731D659EBB" modified="2019-05-08" version="1">MPSPSAVMLPEENKRSLTELSEKDNDAFLTSWEMALEHLRTYKEQEEILPYYSVQHQKDTLELKSARIAKLLEHLHETNSDQDLAKLLTSSGLRKEIVNIITSQWWLGVAPRERLGELLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYL3</accession>
    <name>A0A423TYL3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000957">
        <property type="protein sequence ID" value="ROT81547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6377406at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="299"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1315"/>
            <end position="1326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1326" mass="149792" checksum="B7C5167825743D85" modified="2019-05-08" version="1">MALTRLSTGIQQEDHNTFRLYKAHRGPARCVMLTILNWGCQKAPEVTYEDYLLQNLGFSSKKYKTIFDGAQREKLKCHSRGDEFDITLLYKLIQNTCAGVAPASDSVWTSEDFSRLEFLVNYIKNSRNNLAHNDHEISNSEIVRRLEKLRDVLVTTLKAGRDLYCVQQSEVDALIKQVSDAITAIREHPFAQTDVLQYQNDLLFEDLREIMSTDGAKEVAKIFSRNNLLNLNPVSFISGGDCHLKVDRVFIDIQIYSVESGERKAIDYRDILVYSHETNNYPDDHSINSSQQSIQAKRVIHLVEGDPGSGKTTLLKFIMSDWKKQTNIIKELSDYHLVLYFECLNPYKDSLADFLVSQMPLTSTRFHKSDLVRCLLGLKVLLLIDGLDELNSASKRFFKEIIHVKRNSDISVICTTRSEKLKEISGMISSDLTINYFKLLGIPSNKRGKFVQQYHEELKRRGMSAGNTDSIVQYVENAPQQLNDFFVYPLNLVLFTYLWATRPESVNAVTSVTVLYAEVHSLIVEKLHRRLLDDPDIDYIPSEEIKGRCEQFLDVLYQFSFATLSCNMLYLDQEHVNRLLEVCSETGLAAKHMMSSFLVVELTSSGEQYVERHRFPHKGIQEFYGAQHILSIISNENLAKNRAQVLEALEKCLSKFHISSYEKQEIASWASELSERKRISTLLGKTCPVRFQEKGKYTNLLQHLVGLLRYQTSYLLLHYAEEIVGLLNDSGDLFFDQWADLLKKTDYDALVAKEVARFVCQISWIVRDDQERAAATLIAHRCPRVLSIELFKEPKDLPHLADLLGSAFAQGCEIRLHLHSHWREPKSGSSDGILRALQRSSLNETQEWEYYLEHTWKKSLTQFTGRATSPAVLASLVDTIEELRVAVRTDDEALDWSVCISTCDVFVRLKWIGGIRPSHLPAGVHVAGAGVDPALLCTLPSCADVEYGVISFPEGSLTSKGVEALAKRFYEEKIKVREVLMTCDLEGDVVASFSILVGCHVVQCQGAEIWTREPAPTPEPEYEDYISFNAAGGGVSNDRTQETAAGTEEHLYETFVQVDGSIGSDREESIYETISYDHQPLPFAPHKTDYVPLVPPRATKQPLPLPPRPRQPLPSKYYNLSSELQQRPPMPIPTKLQPDSLSGSLPPKPTLRLPPRQPLKPSVKTRRFKTPRPPMPLPLKPQETQAPKSRRKPPHSSANASKPPQAQAPMASQQVMYPAPVHPWSPAQPPHTVQLLPLCTWPLMADLQWTSWGMPIQRLMPMAPMLQPCISWGMQWGPPGGSLSTITGPALQHPGVQISPPPSASNGWGVHADQNDEDSLYENLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZD6</accession>
    <name>A0A423TZD6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_025038</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SKAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000915">
        <property type="protein sequence ID" value="ROT81811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZD6"/>
    <dbReference type="STRING" id="6689.A0A423TZD6"/>
    <dbReference type="OrthoDB" id="243840at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037781">
        <property type="entry name" value="SKAP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15129:SF0">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15129">
        <property type="entry name" value="SRC-ASSOCIATED ADAPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="PH" evidence="9">
        <location>
            <begin position="80"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="721"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="212"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="433"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="542"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="361"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="600"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="617"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="687"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="781" mass="85998" checksum="017E23AD26EC9693" modified="2019-05-08" version="1">MVLGRGGGDTLDPRHPSQQQQIQDEEYEDFQENNKDDIASVNDTTSLQDQSRDDADDREDVDDVYMESVEAVAFSNVIATCDKHGVLSKKTKGLLRNLKTYHCVASSGMLYLFLKETDDRQRKTIDLSGYTARMATGEDIRDQRKKDSAFEIVGPGKKTHTFIARTPRDKVEWLAALDRTIKSGRKSQSTFALDTLISSDETHRLSQPQILANSPLILPPKPGPQPQQEGKKDDAKPAEDDYYYHDVYEEVGPEGLAGRVLAAGQSQTLPARTQPPPSWVMDPPDYDPVSPDDSPPPLPEGPPPLLGRRPPGRPPLPAVLQDRVNKQASRPLPDAPPETSEGAEDPIGIYCEIEDDMLEAGRESYEQRLAEENEKNWNLTSNANKPRAVSSEGVPSDLQSLSSRMSSNSLVGSLSDEIFMNISENSSAHALPHKFSLRSSTPKTPPKLPPKGIPYPQAADDDSEYKVPTSAIADTEYQIPSSNPVPTDADDARERNSVGEISAPLPMQTYQVPPSQAIVPIKPKCDRKNSIVEEETKQLTSFFSGKEDTNPKNNLKALTRRFEMKSNSLPGEDVKEEKRTPNQGTSVKDMIARINQNKSQVEKDIKSKTKEEPVRPLSSSKSASAVFQVTPPPQEAAPPAAEAESRFAKPALPPRPHNLANGATIVVKPRANEDNRNCDSASRSTSDDDYYETPDDSSLESSSQRNSQDMARVSGGSSDTSSGEYYVAKFAFVATIDQALSFNRGDTILVHDVTSSTGWWRATLKGRTGLVPREYLKKKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U165</accession>
    <name>A0A423U165_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000822">
        <property type="protein sequence ID" value="ROT82445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U165"/>
    <dbReference type="STRING" id="6689.A0A423U165"/>
    <dbReference type="OrthoDB" id="10418600at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1143" mass="130849" checksum="7891C8B8C32A3905" modified="2019-05-08" version="1">MVSTTATTPPDVIDPIEEEPSDGIIQISSNVNKTCDEIEPEDFAQDVVIENKFEMDDFEMALHRLKDSEDSYCAVQTLLSQDPNNTMNSSWYYMDDGLIQMEVGETYQPDVHISEGLLIILPLIDDDGNLIIVVLIRTFNDEPASPIVQISQTFADHGNCHCLKRESFQASNVADDVAFHLSQHFQEKETNITKPRRSRRNAEPDPTMDYINMLDAVPPFRRTIKDVIIARVIEEDCNETTTEPPTTNYYFSRYNYTIGVNYYTTRNNYNTGANYYTWGVNYNTIKDDYTSSVNYTNRHKNNYNTGANYYTRGANYYTRGANYYTRGASYYTRGVNYTIKDDYTSSVNYTNRHKYTIGVNYYTNRHNLTIGVNYYSARNNYTTGANYTRNDCTTGINYYTNRNHIIKNDYTSGVIYYSTRNDYTSGINNTYRHEFTIGVNNYIKDDYTSSINNTNRYNYTVGVNYSTRDNYTSGINYYTNRYSYTTGINYYTTRNQYTSGTTLYTSLHTNRLHGINYYTTRRCQLLHQQVQLHHRYQLLYHQKPVHQRCQLLHQQVQLHHRYQLLYHQKPVHQRATTTPTGTATPPVSTTIPPETSTPAVPTTTPTGTATPPVSTTIPPDTPAVPTTTPTGTATPPVSTTIPPETSTPAVPTTTNRQQLHHRYQLLYHQKPVHQRCTYYTNRYSYTTGINYYTTRNQYTSGATTTPTGTATPPVSTTIPPETTTPAGANYYTNRHSYTTGINYYTTRNQYTSGANYYTNRHSYTTGINYYTTRNQYTSGANYYTNRYSYTTGINYYTTRNQYTSGVTTTPTGTATPPVSTTIPPETSTPAVPTTTPTGQLHHRYQLLYPETTTPAVPTTTPTGTPPVSTTIPPETSTPAVPTTTPTGTATPPVSTTIPPETTTPAVPTTTPTGTATPPVSTTIPPETSTPAVQLLHQQAQLHHRYQLLYHQKPLHQRCQLLHQQVQLHHRYQLLYHQKPVHQQLLHQQVQLHTGINYYTTRNHYTSGANYYTNRQLHHRYQLLYHQKPLHQRCQLLHQQVQLHHGINYYTTRNHYTSGANYYTNRYSYTTGINYYTSRNHYTSGANYYTNRYNDNIGAKNYHTIGVNYHTRRYYNIGINYYSACHNNNIGTIYSTNISIGVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3Q7</accession>
    <name>A0A423U3Q7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U1 small nuclear ribonucleoprotein C</fullName>
            <shortName evidence="9">U1 snRNP C</shortName>
            <shortName evidence="9">U1-C</shortName>
            <shortName evidence="9">U1C</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023499</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA. Interacts (via N-terminus) with TIA1 (via C-terminus); thereby promoting spliceosomal U1 snRNP recruitment to 5' splice sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000700">
        <property type="protein sequence ID" value="ROT83331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3Q7"/>
    <dbReference type="STRING" id="6689.A0A423U3Q7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000059">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="120" mass="13302" checksum="A97E60C1A5A69CAC" modified="2019-05-08" version="1">MPKYYCDYCDTYLTHDSPSVRKTHCQGRKHKENVKIYYQKWMEEQAQNLIDATTAAFKAGKIPKGAAIPPPNNMQAGGGPAGPGGLEVLVVQEGQVGHRTWVAQEVHPEVLAWGIWVLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7G9</accession>
    <name>A0A423U7G9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="2 11">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_022170</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="10">Binds 1 Ca(2+) ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="2 11"/>
    <dbReference type="EMBL" id="QCYY01000516">
        <property type="protein sequence ID" value="ROT84658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7G9"/>
    <dbReference type="STRING" id="6689.A0A423U7G9"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046488">
        <property type="term" value="P:phosphatidylinositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08591">
        <property type="entry name" value="PI-PLCc_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000084">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000008">
        <property type="entry name" value="1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1230.10">
        <property type="entry name" value="Phospholipase C beta, distal C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016280">
        <property type="entry name" value="PLC-beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014815">
        <property type="entry name" value="PLC-beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042531">
        <property type="entry name" value="PLC-beta_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015359">
        <property type="entry name" value="PLC_EF-hand-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF149">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE CLASSES I AND II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09279">
        <property type="entry name" value="EF-hand_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08703">
        <property type="entry name" value="PLC-beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000956">
        <property type="entry name" value="PLC-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69989">
        <property type="entry name" value="C-terminal domain of PLC-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="14">
        <location>
            <begin position="417"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="13">
        <location>
            <begin position="533"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="301"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="711"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="844"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="966"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1008"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="755"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="859"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="966"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000956-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000956-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT84658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1064" mass="121379" checksum="DDB6D0635C3DC9D5" modified="2019-05-08" version="1">MRIDNNTDCRSYCNSVVLDINGVFFPQNDSVSLDKFTWDTFLNFYNRLTCRLEVEKVFCEITEQPYNTSRKTKLRGMNVEQLVNFLNKEQRDPRLNEILYPYADAAKAREVIRDYEPYKENIAKNVLSCEGFLKYLMSEENVVMSVEKLDQYADMDQPLSHYFINSSHNTYLIGHQFTGRSSVEMYRQCLLAGCRCVELDFWNGRTDEPVIVHGYTLVPEISAKDVIESIAESAFKTSEWPVILSFENHCGPRQQAKIASYCREFFGDMLLDSPLENFKLEPNNPLPPPSSLKRKIIIKNKKKHRTHHHHHKKNAPGGESQFHVELNTTGEPRHTEMQGNGEIPRPPLEKEGSRESSEEENEVANGEIPDGGALEEVESSSSEEDEGPPTPDGVHSRERTSSEGSAANAEEEAGAEISALVNYVQPVHFHSFEVSEKRGRSYEMSSFVETQASNLLKESPMEFVNYNKRQLSRVYPRGTRVDSSNFLPHQFWNAGCQLVALNYQSLDLAMQLNLGIFEFNNRSGYLLKPDFMRRPDRRFDPFAESTVDGIIAGTVSVKVISGQFLSDKRAGCYVEVEMYGLPADTVRKRFRTKTVPNNCINPVWDEEPFVLKKVVLPELATIRIVAYEEGGRVALGNRVLPIVGLRPGYKHIPLRNEAGQPLGVSTLFVHLKVGDYVPHGLSDFAEALANPIKYQSELEKRTQQLAVFQDDEEGEETEGEVPQTPVSKQESSVNQGGGGGQTSTGDERQVKAPKNKSNGEVPDTTTTANESTPVGTRRQNSISAKVHMNTKTGDDKPEREKESSLTLLETSKLVIEAESLEKLWSGKIVKDKKLEFEKSLEKLRKKHEKERQSQIQQHEKKRGQIQKSHTKLVKKLSSNKPVEPSGRETTQDLNTVQEELESRLQEEDKLHKTSLCELSMEHLIAEKKLQEKYHDTIYAALDKAMRMSQAEQLKKLQTIHDKQVEDIKRKTEEQHREKRKGLGKTTVDKEELSRIKREISKQIVAEGIQERQKLTDIHEKKKTELEKQHEDVRTQFEEDKQKAKNNIDMEYEEKRAKLEEGISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7Z9</accession>
    <name>A0A423U7Z9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">C7M84_021985</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000492">
        <property type="protein sequence ID" value="ROT84822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7Z9"/>
    <dbReference type="STRING" id="6689.A0A423U7Z9"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF39">
        <property type="entry name" value="INNEXIN INX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="263"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT84822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="369" mass="42266" checksum="B519F17BAD58CB5D" modified="2019-05-08" version="1">MCCFSPVLFDALVGPPSALPCDKGRESVNKDCAISEAEQWEELRILVRCGGGNSAAPPFHPNPTTTTLSRETLERGSQVAQPGVGSPTGYDEEEVEERWRFHNYYQWVVFFLFFQAILCYMPKFVWNNAEGGLMKTIANGLNPGLFREDEVSSRKKVIIDYIVKHIRMHNGYVFKYWFCELLCFINIVGQLFLIDRFLGGEFLTYGPRVVEYSEMDQEERVDPMIYVFPRMTKCHFHKFGPSGTLERHDAFCLLPLNILNEKVFIMIWFWFVILACLLGALILYRVALFTLPGLRPRAMHKHNKSVSLETVQAITNKTSIGDWWILYVLSTNIDPLIYRDIMTTLAKEIETANSNNPYNSAGLYSSSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8F8</accession>
    <name>A0A423U8F8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_021656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000458">
        <property type="protein sequence ID" value="ROT84978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8F8"/>
    <dbReference type="STRING" id="6689.A0A423U8F8"/>
    <dbReference type="OrthoDB" id="694479at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019533790" evidence="3">
        <location>
            <begin position="27"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1087" mass="121095" checksum="CC6CE61232FE47D2" modified="2019-05-08" version="1">MSLCHCLSHILILLAALLASPQQASGEACPCTWSATDAALSCRDLGLQSVPRDCFLDHPEAVLLDLSGNSIESLGEDDFSGLDAVEALWLSRNKISSLHSRTFRNLSALAELHLDQNALEVLPEGMLAYQPSIREFSVDNNNLIKLPLSLFADGLQAPVTLNLTSNYLRVVPCSAVSSLPVNSTVSADYVQIWAQHEEEMASCSLLNLPELVSLCMPVDTRSNSIDCTALREPFSPLKASLAESESHRFFDGWTEHIVFSADVDDLMGEPPSQVSCLPDDLDVAGSFLVFHRYNPDLQLEGLFFDMADLPSHTSELTNSVTIKADTVVLTRPIPPLRYRLTVSARNVVLAHPLLMEAPTTLYPPTTTETFYQLQVSAGRVNGVTVIQYEHGLLTVRLLDGADVVAKHSCQPLPAYSEDEVREWVSARQLWLTVYCSSTLRESDERETLLYARDLASFVTRLTTNWTKVDMVGTSQRATNLLYDINAALSNSLLPRNVPYLSVSVYAEMVPYLADTIAVYKEAYDDLRRKLMVNAERLFDMNIHFEERKADLEFMQSNAQRAVEMAEEVHSVHSAQLQNHVSWAISSWKAIMDIYENVLASRPQVNDALDRAEEGLKAYKRQQRFVSFLNVGTTFARCIMGFPGGTIGIISNVGQVVSSAFEFKSFDETMEEITEKIEAVNVMMVKTESFMSAVPPLPPADGDQLAWLMTFNDSETLYAIARQAGVTADQWESAGVYSIKCLADEDFSDKVDGVKNLKMKLNELRVWSQALAEQVQAFCEYVASILEEVTNLAEDAEAVEEGSAALDSVNGMLVDQAVTEENYKEHIVEQNLAVLDVMMKLFLKSRSDILAINVILHEYCSAYFYAFFKDCDPANSPSLWDNYDTVLYKLNKIQFESLNSIASLSPPPQPFQKTIRVLDSASGCEGGAATSEGAACPVSALAFSGSSSFNLAEHWGAGLSFGARIRMDRLRIYLEGLHEHTVTIDVKRPAIFNDTYKGQEFTFRGHLEECRVEYEETALLTANPSHGDEKAVSYVTDCSTHQQYQLYYYRTSPDGMYTFTWREFQLGVDYSNLTALELYLEGSWIPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9A3</accession>
    <name>A0A423U9A3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000337">
        <property type="protein sequence ID" value="ROT85272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="720" mass="77786" checksum="26BBD24630B5EE42" modified="2019-05-08" version="1">MRCAPRTPVRIVRRRVPWGARPHAGADGRKAGAHGERARTPVRIIRRRVRMGSAPARQCGSSESGCPWGEPLHARADVGRRVRMESAPHASADRRKAGAHGERARTPVRIIRRRVPMGSAPTCQCGSSEGGCAWRARPHASADHQKAGAMGAPPHASADHQKAVPHGSAQCGSSEAGVRMGAPTRQCGSSEGGCHADHQKRMGARPHAASSEGGCAWGARPHASADHQKRVWSAPRTPVRIGKAGAHGERPHASADRQKEGAHGERPRTPVRIIRRRVPMGSAPARQCGFGRASWGERPARQCGSWCPWGAPRTPVRIIRRRVPTGSAPHASADRQKRCPWERPRTPVRIIRRRCPWGAQPARPVRIVRRPVAMRKRPPHATCVSSEGVCPWGARHTPAADRRKGGCAHXVRIIRRRVRMGSAPARQCGSSESGCHGERPCTPVRMGRKAGAHGERAHTPVRIVGRRVRMGARPHASADHQKAGAHGERARTPVRMVGRRVPMGSAPARQCGSSEGGCPWEPPARQCGSSKAVALGSAPARQCGSSEGGAHGERVRTPVRIIRRRVRMGSASARQCGWSEGGCAWRARPHASADRRKAVRMGTRPHASADHQKAGAHGERPARQCIMRMGGTPVRMVGRRVRMGARPHASADRRKAGAHRERARTPVRIIRKRVPMGSVPARQCGWSEGGCPWGAPPHASADHQKAGAHGERARTPVRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA99</accession>
    <name>A0A423UA99_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_010355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000231">
        <property type="protein sequence ID" value="ROT85613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF127">
        <property type="entry name" value="BLOODY FINGERS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="19"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="449"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="478"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="645"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="670"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="829"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="897"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="951"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="982"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1010"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1038"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1064"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1093"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1151"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1179"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="1244"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="701"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1581" mass="178872" checksum="18F9F3C1CAE875CB" modified="2019-05-08" version="1">MECSVCRVQFQPGDISLRVIDAVTEHTHTPMKDLVSSTLQRSLCPTDLICTKCADLFNEKDRLQKMTVDMDRNIMTKIKDSSKKSPDSGGTISIVMGETFTNEDIQAELERQYKNISIDSTSAQTAAKSIDEEVDPLEPRRAPKRRRGRPPKGNRKQKLEDIPEAPPLMVNQREKRKRSAKFNTFLEVLRGEKDFYIEDEELQEPKVAKKSGGRKKKMNFGIVPVEDKSKEMMEKMCIIQVTEVDRHEKEVPTVDKDKLDLDEVVQEILGISADPGSSLIEDIESLEHDGEDLISAIDEMTSEQGIIETNSRGPAKTEEIGIRSWPNIKSEDIATPSIEVTGFDEDLAASMPSLEVTITQSEDNTLQAVINDPDVLSAIVKEEAVEVLDEKMVKSENAGDCDEGSDLKKYRCKLCTETFSSKSDARRHALEVHMQSDLCDNDKNSQGSFRCCECDRVFPTARGRDRHLLYMHLKHKPVQCTDCCRSYNSFRPLERHLREFHDKNPTLHCEACEAEFVLGTALEHHKEIMHPVLNKNKLAKSTVNTKLKENVKQHKVVECPICHQKVYGIKSLKLHHQKMHKGQEYTCKYCKYKTNCLSTMHRHMVRIHKALKLELYNCIKCRAGYQYPKDLEEHCISVHKIDPSFLCQHCGEKFACIEMLRFHRKSHRAFSCKLCHLGFMKEEALEEHVKSVHNCDPVGLTENGDVTSQSENESVSEKADAIDTEAESTEKAAAAPNSKVLVIATDGSVQVKEEVKEASTAPPVPSEDVTLHLQQTREGGLEEMDMLNPLKGHKVKDLPKKMNCPVCNKVLTTKFLRTHMLSHKGDLPHKCHVCGKAYAQGTLLRKHMKNRHYDEFLKLGNKNPKKPKIGCDFCHEIYDNIYALEEHLWLHMEEKTIECSDCKIKFGMASNLREHYKSHYFKEARPCPVCKREFKSIGFYNEHVERCQKRWKCEQCGLECDTQEYYRKHQRAEHGGENVIRYQCNLCEKSFVERHRYDDHMITHSAEKAFTCHICDKQFKRQRPLKDHLVRAHSDEQMMCTYCRKTFSTQQELDQHKKKHKREFPCTACGHVYASKEALTNHLMVHHSETTPHTCHICNQTFVKQANLKAHLITHNPNTPNICHVDGCHKMFRSEGLLRTHVARRHHELQYECSVCDRKFGLESDLTRHMATHNTGSSLPCSECGKPFRSEAQLERHLLTHTQEKPYECGICQHTAATRHQLLRHIQIDHGINDATTQLVVNRWRCSVCSKMFVVRGSLLRHLQDHATHGVQAQGHAVKTRSTPSTLPEIPITGSATDAAAATNTFLEQVSTLSWQDLTPLLRLHVMADEEASDVESAAVAADVWLCPGCLHATQTEEEMRDHLVETQQCQEAVILQLAGGLANAEDLDDDSVAEEHLLNEEGTGAVLQLTSNEEGLQYVIVQEEEGGTTQLNGDTPVVPEVQAEVASDDRNMQVLVSMDDSLHQLLRQPAHGDIQIVVGNTAPLKQFLTENETDPNVPVPSTSASDQVQDNLSTDAPILNGSELLLQTADGRLVLQQTVGGVTQYQLVEGVPTGAEEVDANLSLLPSHTPSLSSDFILSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAB1</accession>
    <name>A0A423UAB1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative furin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_010759</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000237">
        <property type="protein sequence ID" value="ROT85600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAB1"/>
    <dbReference type="STRING" id="6689.A0A423UAB1"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000006">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000021">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF23">
        <property type="entry name" value="FURIN-LIKE PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0165">Cleavage on pair of basic residues</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019263580" evidence="12">
        <location>
            <begin position="19"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="13">
        <location>
            <begin position="592"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10 11">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10 11">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="10 11">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT85600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="717" mass="78150" checksum="472EAB4CACB750CA" modified="2019-05-08" version="1">MALLLYAGLALWAVPAQAHSNYRDFHHDPAFYLNRDNFTTPQVYWGQQGAGAGELTDHLALEIDAEEGRARELASKPSGRQKRSLRNSALLGALAREPGVRWVDQQKSLIRVKRRAPFGLTYRTKAHTQRSLAEVLRRRQEERGRDESNLLPKERDFWVQEDEDVVDRSRVGARISMRLPGSFVRPYRGGYGGKRMSFGKRGYLRDVGDLDSQPDWAMGSEEGGAWTQTMNGLDDLAGTGLDFNDPRFKDQWYLHNTGQLGRAGYDLNVVGAWRRGYTGRGVVLSVLDDGIQAENADIADNYAKDISFSVVRDGQDPRDASPRLDPGFSNSHGTYCAAAIAAVSNNQVCGVGVAYDAKVGGVRLVDGSVTDIQEATALSRNVEAVGVFSASWGPTDDGTKAEGPGRGVEKKRVGRGGKGVIYVWASGNGGLEGDNCNLDGYVSSIFTLAVSALTDAGASVFYGEPCASTLAGVFVGGEHTLEAALEKRERHQQDIHLVVPELDGHCSSSFQGSSAAAPLMAGVVALVLQANPSLTWRDVQHLVVRTARPTREAATEAGWQTNGLGRQFHLMQGYGAVDAGKLVESALSWENVGPQKIRSIKMFDGYRPIPPNDWLNITGKLESTNSMVAVEHVVANITLSHKQRGMLRIYIVSPSGTASQVLTHRRRDKSTSGFTRWGFMSVHFWGENPEGRWAVAIKDDSGLKGSLRKVDFVVFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYC8</accession>
    <name>A0A3R7LYC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014026</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002745">
        <property type="protein sequence ID" value="ROT67868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYC8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="117" mass="13810" checksum="0E122E4BEDD05D11" modified="2019-04-10" version="1">MTDEDVVTMDYETVKEAAVEDADYQRLIARGRTGDWPASKCKEFIGLRPYYQNFQDDKGSDQIPQRIELRWNARRDSELKRFVKTNFLIVNPKEELVYDLRKVLRDCIVEISAMTGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2J2</accession>
    <name>A0A3R7M2J2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12">Kinetochore protein Spc24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_016536</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Chromosome</location>
            <location evidence="12">Centromere</location>
            <location evidence="12">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the SPC24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2J2"/>
    <dbReference type="STRING" id="6689.A0A3R7M2J2"/>
    <dbReference type="OrthoDB" id="6349744at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11565">
        <property type="entry name" value="RWD_Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.570">
        <property type="entry name" value="Ncd80 complex, Spc24 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013252">
        <property type="entry name" value="Ndc80_Spc24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22142:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08286">
        <property type="entry name" value="Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 12" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 12" id="KW-0137">Centromere</keyword>
    <keyword evidence="3 12" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 12" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5 12" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="80"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT65505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25406" checksum="87BAC426D7CF8B65" modified="2019-04-10" version="1">MRKVPSNMDTPNARFCKMGVGKNGESTIERDIAGLEEMTSQAISLYANNRVNSAINASKDILVSSLAACEHSRLALKETIRELLQVEEAESNALDELRSETLGPGASQVVSQIAQAKRRMEEIKEEIKSVTGSISHTEQLEHSLEQRAKSSSKHTTAVVPKIKADVTTFTQISHLKWDYTAPENVVKGFILRPEKRDITPFKLDTSSHSQFFITNFLWQQIAADSDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2R8</accession>
    <name>A0A3R7M2R8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamma-tubulin complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_011518</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002451">
        <property type="protein sequence ID" value="ROT70212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2R8"/>
    <dbReference type="STRING" id="6689.A0A3R7M2R8"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="56"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="349"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="484"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT70212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="739" mass="84051" checksum="6422F5166A007B3B" modified="2019-04-10" version="1">MRAVERGEKKNTLGPPTPSWLDNRPYHTLDFVQVEHRPDVGALGKVASTSQEHQLIEDLLSLMMGIEGMYITVQPPAKHYDAPEFTVDPSVEPSLSALVSRILPLCGHYSQLVRFVEDKSLYHHGLVNQALAAALTSLIKDYMLLVTQLEAQHQRWALTLHKLWFYVEKTMAVMDMLACITRIITKSEAHGGSVLSLLHDRTLSLTGCGQLQEVMVFLTQAAAVPYMNMLAKWLYRGIINDPYNEFMVVDRESGTEENEDQDLADDYWEKRYTIIPHNIPAFLQMHADVILRTGKYLNVIRQSDHSVVCPDQEELAYSIRDPSYTEVIERTYSFASKRLLELLMKEKDLMGRLRSVKHYFLLDQGDFVVQLMSLCEDELSKNIDDVVPTRLESLLELALRTSAANNDLYKDDIHIETEDEREYYPQEERLQLSGLQGFSLGYRVTWPVSLVLDRKTIACYQMIFRHLFYCKHVERLLCRVWVSNKVENVDEVLAFHNDFLSGCLKDCMLTSPELLRMISKLTGICVNFANFIEESPEPAATTHEDSQSFEQTISRFELQFSGMIYTLMEKISEMGRDNYNDALVNFHSLTLTINFGLSSNHAYTSLPHYHLLKFTSLTPQSPEPQFLTPPSTNILTQYMLVAEVGASTRVASISPPSGLPPMLLLDLRHHFLDTEPPSRPPSKTYPESWPSVGALGPALVQLFRQVLLEPTPPSDVTSSHPFALESGRFKVKARPTCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3W2</accession>
    <name>A0A3R7M3W2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002196">
        <property type="protein sequence ID" value="ROT72168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3W2"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001234">
        <property type="term" value="P:negative regulation of apoptotic signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10428">
        <property type="entry name" value="LFG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF127">
        <property type="entry name" value="PROTEIN LIFEGUARD 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="276" mass="30925" checksum="E679F5A946F52A51" modified="2019-04-10" version="1">MAHYHMDNGQVDVEVAEHRRQVGQTQPAYNGSGGGMPIQDGAGLPKDDVLPEQFGGSFSDKAIRHAFIRKVYLILMVQLLVTLGIVSLFTFHSGVKRFVRQNMWVYFLSYGVFLVTYITLVCCSGVRRRWPGNFIMLGIFTLSLSYMTGTIASTYDTDIVIMTVGITCAICFLITLFATQTKYDFTGCGIYLFVASMVLFIFGIIAIFTFSKIMHTIYSAGIALLFSMYLVYDTQMVVGGRKHQISPEEHIYGALTLYLDIVYIFISLLSLFGNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M490</accession>
    <name>A0A3R7M490_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_010198</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002291">
        <property type="protein sequence ID" value="ROT71482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M490"/>
    <dbReference type="STRING" id="6689.A0A3R7M490"/>
    <dbReference type="OrthoDB" id="1740265at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.400.10:FF:000001">
        <property type="entry name" value="Maltase A3, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="entry name" value="Oligo-1,6-glucosidase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357">
        <property type="entry name" value="ALPHA-AMYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF179">
        <property type="entry name" value="NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="7">
        <location>
            <begin position="48"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT71482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="348" mass="40662" checksum="A5167478089B0580" modified="2019-04-10" version="1">MASKRCFGIFFFLLFLIIIGVTIICIIAKDGIKHQETYPFWQRTIVYQVYPRSFCDHDGDGTGDLQGILSKADYLKELGVGTVWLSPIFSSPMADFGYDVSNFTAVEPLFGTMDDFDALRAALHDRGEPAAGVGLRAEPSSDEHEWFVKSRRREEPYTDYYIWADPKGFDEAGQPIPPNNWLSVFRGSAWAWAEERQQFYFHQFLAKQPDLNYRNQRVREEMMQVLRFWLDRGADGFRVDAVKFLFEVEDINQNESIAIDPETDDPLDYYYLNHTLTINQPETLEVVREWRDILDQYSDRVMIGNEGTIDDDIASGDELLRQRQRFPLERLSPFNFLLIDRFHNRKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5H1</accession>
    <name>A0A3R7M5H1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">15-hydroxyprostaglandin dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="3">1.1.1.141</ecNumber>
            <ecNumber evidence="4">1.1.1.232</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Eicosanoid/docosanoid dehydrogenase [NAD(+)]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Prostaglandin dehydrogenase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_009059</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NAD-dependent dehydrogenation (oxidation) of a broad array of hydroxylated polyunsaturated fatty acids (mainly eicosanoids and docosanoids, including prostaglandins, lipoxins and resolvins), yielding their corresponding keto (oxo) metabolites. Decreases the levels of the pro-proliferative prostaglandins such as prostaglandin E2 (whose activity is increased in cancer because of an increase in the expression of cyclooxygenase 2) and generates oxo-fatty acid products that can profoundly influence cell function by abrogating pro-inflammatory cytokine expression. Converts resolvins E1, D1 and D2 to their oxo products, which represents a mode of resolvin inactivation. Resolvin E1 plays important roles during the resolution phase of acute inflammation, while resolvins D1 and D2 have a unique role in obesity-induced adipose inflammation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48640"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78836"/>
            <dbReference type="ChEBI" id="CHEBI:90697"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:48641"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23260"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57409"/>
            <dbReference type="ChEBI" id="CHEBI:57410"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.232"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="20">
            <dbReference type="Rhea" id="RHEA:23261"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD(+) = 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90866"/>
            <dbReference type="ChEBI" id="CHEBI:90867"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:48953"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NADH + H(+) = (5S,6R,15S)-trihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:41596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78325"/>
            <dbReference type="ChEBI" id="CHEBI:78329"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:41597"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>lipoxin A4 + NAD(+) = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:41572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67026"/>
            <dbReference type="ChEBI" id="CHEBI:78311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:41573"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>prostaglandin A1 + NAD(+) = 15-oxo-prostaglandin A1 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:41263"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57398"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:85072"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:41264"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>prostaglandin E1 + NAD(+) = 15-oxoprostaglandin E1 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16477"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57397"/>
            <dbReference type="ChEBI" id="CHEBI:57401"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:16478"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11876"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57400"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:606564"/>
            <dbReference type="EC" id="1.1.1.141"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:11877"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>resolvin D1 + NAD(+) = 17-oxoresolvin D1 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132079"/>
            <dbReference type="ChEBI" id="CHEBI:132081"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:50129"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>resolvin D1 + NAD(+) = 8-oxoresolvin D1 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50124"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132079"/>
            <dbReference type="ChEBI" id="CHEBI:132080"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50125"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>resolvin D2 + NAD(+) = 16-oxoresolvin D2 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:133367"/>
            <dbReference type="ChEBI" id="CHEBI:137498"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="19">
            <dbReference type="Rhea" id="RHEA:53589"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>resolvin D2 + NAD(+) = 7-oxoresolvin D2 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:133367"/>
            <dbReference type="ChEBI" id="CHEBI:137497"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:53585"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>resolvin E1 + NAD(+) = 18-oxo-resolvin E1 + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49244"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:91000"/>
            <dbReference type="ChEBI" id="CHEBI:91001"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:49245"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.141" evidence="3"/>
    <dbReference type="EC" id="1.1.1.232" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002138">
        <property type="protein sequence ID" value="ROT72527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5H1"/>
    <dbReference type="STRING" id="6689.A0A3R7M5H1"/>
    <dbReference type="OrthoDB" id="6368354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047034">
        <property type="term" value="F:15-hydroxyicosatetraenoate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016404">
        <property type="term" value="F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="22">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00049188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT72527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="19278" checksum="19AD854A189B7766" modified="2019-04-10" version="1">MGGCCTRSKTLETAVQRPPVAMQIQGSVVLITGAARGLGRCFAETLLGRGAKVCLTDIDAEAGAETVTELQAQHGGDNAMFFKCDVTKDEDFNGAWDAAVEKFGPVTLLVNNAGLGNEQNWQLTLNVNIRKTEREAAWRSRRRKSPTSWNRQSPLSKSLPLQEPVPLRGLGVTDNVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M640</accession>
    <name>A0A3R7M640_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Reticulon-4-interacting protein 1-like protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007537</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001956">
        <property type="protein sequence ID" value="ROT73976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M640"/>
    <dbReference type="STRING" id="6689.A0A3R7M640"/>
    <dbReference type="OrthoDB" id="9930022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08248">
        <property type="entry name" value="RTN4I1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037397">
        <property type="entry name" value="RTN4IP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="137"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="53835" checksum="872601907462C9D4" modified="2019-04-10" version="1">MDHLLFLAQERMEWLQVTLHSGSRSFSHSLASVRDGARGFYLESVNAVKNQRLSGELVEKVRGWLMKLKEVLDDFRPSELYNRLWVFLLTEVTRTHMYFGGVCFLFGGIIGITVGMKLRNSVVAPQRMRAVVTNSYRGIEAIGVVEDVVAPRIVQPNQVLVQVKAAGIDYLDIKVAEGYGRVLRRQLNKYNPNTEGEFPVVLGRDCSGIVVAVGKNVSKVEQGNEVWLACPFYHPGTLSEYVVVADDLVAPKPSQLTFEGAAALPYSIMTAWDALVTQGGLGPDSTAGKRILVHAGVSGVGVVAIQLVRAWGGHVTTTVSSRAAPLAHMLGADDVITYDNSNFDKELMLREKYDVILNTVGEVLHESCLKHCVPGGLVVTATSSQLASDSYGYVTGALYSLGMRLRYWFTQAPWLTGGRWGTLEVCGHVLESVAPLVEAGRLQAVVDKAYSAQDAEVAFAHVAKGEQIGRTVVRFSNNPPVRNLGMAFWQDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDK1</accession>
    <name>A0A3R7MDK1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001305">
        <property type="protein sequence ID" value="ROT78997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDK1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="43725" checksum="B6982148613845F7" modified="2019-04-10" version="1">MLLSPLPFCFPHSFYTLSRPSFFLFSLSLLLCHFSYSLPHLSFIHYFSPLSSSLPLPLLTSVLFIPQILLPFPSPSLSLSLAQFSLSPKFSFPCPLPFSPSLYPFIPILLPSPLPLFSSVLFIPKFPFPLSLPLPPFSSVLFIPQILLPFPSPSLWFSPLYPPNSPSLPLSLSLVQFSLSPKFSFPSLSLLSSVLFIPNSPSLPLSLPYPQILLPFPLLPLVQFSLSPNSPSLPPLPPFSSVLFYPPNSPSPSPLLPLVQFSLSPKFSFPSPLLSFSSVLFIPKFSFPFPSPSLLVQFSLSPKFSFPSPLPPFSSFSSLYPPNSPSLPLSLPLVQFSLSPKFSFPFHLPLFSSVLFIPQILPTFPSTEEVLARLRLLPASWLPPPPVRMTKKNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIS1</accession>
    <name>A0A3R7MIS1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024038</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000775">
        <property type="protein sequence ID" value="ROT82794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIS1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="43260" checksum="74C8BBE16E5E1152" modified="2019-04-10" version="1">MPLRDALPSAAAGCPLPSPAPWRPALGAAVRSFPLDWLPILALFFSLGSPSVPLSSSSTLASWPCITWFSLPQLSFPGFLILLSFHFLSPISFPLPPSLSLSLFLSMALPPIFAGFPSPPSKTLSIWLPILALFFLLGSPSVPLSSLLDSRFLALYSLLALFLSSPSLAFSFLCHFISFSPSSFLSPPFSLSLCSLSLHELLSVVFLSHLPLPSLFPSFLPSVFFSFFLLLKLSLFFTLSSCCFPSFLFLVFFPSTPPFPPTLSSLRPSPSASSGPNRASRDPRRLRHTEQKRLTARHSIPSTVSPRGSFSTCVMEHGRRGGIGLDPREETLFGLYECLKVWFRQRGNAIGFWRSSPVSSWFWGRKQGANLPLVACVGRTVLLVVVAVFLGLGLGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLR7</accession>
    <name>A0A3R7MLR7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003157">
        <property type="protein sequence ID" value="ROT65016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLR7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="472" mass="51919" checksum="BA655D7D353AD4DA" modified="2019-04-10" version="1">MGREILPNLLAPSNPPPHSLLKFLSHPSSPLSPFPHPFFLPIAPIPLPLPYHTHPIPTFLSPYPHSFFLPLFSIPLPLPYHPPPHPPLSLPIPLPLLPPSSLSPHTPLPHLIPIFLSPYPHPFFLPPPYHPHTPPPPTPSPAGHPRLGTCHPGSWVLLTTAVTPRSPNPRFPLSLFYHTFLHLPSSPLRFTSSFETISTLLFPLTPTLLHLNSNTPSPHSNTPPSPRLTPNSPLSRLTPTLPTFPSLHSPLSPHSNTPPFSPNSNTPPFSPHSNSPPFSPYSNTPPLSPHSNTPPFSPNNARLTPTLPPLSPHSNTPLFFSLQSSLFPLTPTPLSPHSNTPYFPSLQHTSLPSFQHTSPLTPTPLPHKQPYPSPPPNPSSTSTPIHIPFTNPHPLQPIHPHLHQSILYLHPNPHPFHLHPIHKPSTSTSTQSTQSTFFRPRPPPTLPLPRDCKAKMKPLSKVPSALTGERVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MM41</accession>
    <name>A0A3R7MM41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative peroxidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_000756</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MM41"/>
    <dbReference type="STRING" id="6689.A0A3R7MM41"/>
    <dbReference type="OrthoDB" id="6339244at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.640.10">
        <property type="entry name" value="Haem peroxidase domain superfamily, animal type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019791">
        <property type="entry name" value="Haem_peroxidase_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037120">
        <property type="entry name" value="Haem_peroxidase_sf_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475:SF4">
        <property type="entry name" value="CHORION PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11475">
        <property type="entry name" value="OXIDASE/PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03098">
        <property type="entry name" value="An_peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00457">
        <property type="entry name" value="ANPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50292">
        <property type="entry name" value="PEROXIDASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="585" mass="65782" checksum="E19821B385A3622B" modified="2019-04-10" version="1">MNEAVWMRGRVTRTGELLESTSKTILGMIRKTRVGKRCPEDWLLKGLEKHVIPLMNIDKDLSEELGLVMSFRCMVGSPYPNVDGTCVNQESPDLGAIGAKFLRLQPAAAGKDGFSLRESVSGEKTLPSARAVANLLRNHLQKPPVTGVFGEWGHFIQRDSFSIPESPWAEDVDCCATPEVEDCAPIYLEKDDPDHSTIQCMSFKRSAKAQAILGHRETLSLVSTYLDATPVYGPTNEVAFSRKTGYFGYLKAPEKDEEETASGKKKEVKCAAPESFQGCFQLAEGDDWLENLRLLFVMEHNRIVDALAEINSHFDDSLLYNEARRITIAEYNHITFKEYLPVVMGEELVKKHSLNPGAEGPAAGYIKEVNPGILNSFAVASYRNPSMHTEWRKEWGPTEILESSHYSAVREDPYQDLLAMDIQRGRDQGMVGYLTWRRFCDSTHSYNTWEDLEKGLPKELVNDLKELYQDEIDDIDALVALLEKPDEEDGGIVGKTFTCLLADQFARLKTGNRLFWEHDSSLLTVEQRDFIKTSSLAKLLCRNTPPSINLFILSNSHHGFPYSPIRFSSFIFSPPLIFSPPPPPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQ01</accession>
    <name>A0A3R7MQ01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002848">
        <property type="protein sequence ID" value="ROT67108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQ01"/>
    <dbReference type="STRING" id="6689.A0A3R7MQ01"/>
    <dbReference type="OrthoDB" id="6349622at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="116"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="48249" checksum="B1C218FA0BB67DDB" modified="2019-04-10" version="1">MARPCRTLGQLARELQRTDPRRRPALSAVIRRLDWCFLFGCDSESEAPARTRAKRRPEAQRRCLSCQGRGFRRGGEAPSLRVPSSNTKGVEIRRSGLGCCLQSHRFRASSNGARRQEARDPCSRGRLSEVTPPQRRQGGTRRGRAGRHCWSAGATATLCSSWPSGERFGHFQEEFKFLKKVGGAGGSPRALGICSNPPAILCSFVGRSTLEKVLEESKCSDEELLRLSRSLCVAVQEVHGRGVIHNDLMDDNVVVDKATGRVHVIDFGTACRPGHDCGFSDSSNDYLAPEILGGGPSTAASDAFSVGAMLELISDQMARPCRTLGQLARELQRTDPRRRPALSAVIRRLDCAVKEELGEGASGKALLVRWGDGDAVLKLAHSGERFGHFQEEFKFLKKVGGAGGSPRALGICSNPPAILCSFVGRSTLEKVLEESKCSDESCCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQ30</accession>
    <name>A0A3R7MQ30_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002840">
        <property type="protein sequence ID" value="ROT67165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQ30"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="489" mass="54482" checksum="C052F40BCA4F44A0" modified="2019-04-10" version="1">MRRKIGELNVRPLPLLSSYPSLLFPPLSCFCFSDSTSLSHFSTLFSFFYILPLFAHFLFPSIFLPLSMARFFPPYSSFSFPFFLSLSLPPPPFSLFPSPPFPSHTSIFLLSSSHLSPLFICSPFPSSAFFLFSSSLSLSLPSPLIRSSPFLLLSSPSLPLIPPLPPFLLSSPSLPLIISPFPAPSFNSQYNTCSGTPSQHQDTRLIALPFSSLSPILPFLPSLLFSPFFPLCFSALSSLSAFLPFLLSLLFSPFFSLSPFSPPFFLLLFCPFFSLSFLPFLLSLLFSPFFPLSFSPLSSLSAFLPISIPPLPSVFLSSFLFPYSLFIFSFLFFSCLSFYFPPFSLLPFLTPFPFFASSSFFLSPFSSILLLLPSTLSVHFFLFEFPSSLSLHFLPSSFLPLSPFPAFPQHIISPPSSFSSFSLLSLSPHFPSFLFLPLFPLSSFSSFSLLPSSYFPSFILGSLFPSALPSLFSYDLFSSRVRLKRGTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MS66</accession>
    <name>A0A3R7MS66_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">AmphiDkk3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_013373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dickkopf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002662">
        <property type="protein sequence ID" value="ROT68482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MS66"/>
    <dbReference type="OrthoDB" id="4321958at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039706">
        <property type="term" value="F:co-receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048019">
        <property type="term" value="F:receptor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006796">
        <property type="entry name" value="Dickkopf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039863">
        <property type="entry name" value="DKK1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12113:SF31">
        <property type="entry name" value="DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12113">
        <property type="entry name" value="DICKKOPF3-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04706">
        <property type="entry name" value="Dickkopf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018622103" evidence="8">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Dickkopf N-terminal cysteine-rich" evidence="9">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT68482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="211" mass="23976" checksum="627290E559E26D48" modified="2019-04-10" version="1">MNLCLFFLTVGCLVTPCTAQGLSWLFRRLHKAGRHNIRDLSGGRHNSRQVAADQPFNFYEHLRLCTNDRVCGRGQFCDQHYGVCRDHVTEGRECRRDAMCEGGYACMFGLCQKRIKRGREGARCRKERDCGAGMCCARRHGEQVCQRRVPLGHKCYVPEGGLDYSMNQLCPCESGLVCKYTAQQPPSRHQLMALMSAHEDMRCATPSHRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSB2</accession>
    <name>A0A3R7MSB2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="6">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_013268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002655">
        <property type="protein sequence ID" value="ROT68585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSB2"/>
    <dbReference type="STRING" id="6689.A0A3R7MSB2"/>
    <dbReference type="OrthoDB" id="10263824at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048821">
        <property type="term" value="P:erythrocyte development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042541">
        <property type="term" value="P:hemoglobin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="88"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT68585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="54331" checksum="02A0DA2E1983F6CE" modified="2019-04-10" version="1">MTSQAEGEKKCPFLNNKNLVKQASLEVQEDIIDLAAREQEQELFPYNDFFQEQIARKKADHSYRVFKKVSRMASQFPKAKEYSWGEKEITVWCSNDYLGMSRHEKVREAVKKSLEEHGAGAGGTRNISGNTVLHETMEAKLASIHRKDAALLFTSCYVANDSTLYTLAKALPGCHIFSDEGNHASMIQGIRNSGAPKHIFRHNDPKHLEELLKSVDVSTPKIVAFETVHSMTGAVCPLKELCDVAHKYGAITFVDEVHAVGLYGENGAGIADRDGLQDNIDIVSGTLGKAFGNIGGYIAGNETLVDMIRSYAAGFIFTTSLPPTVVSGALAAVTILSSEEGRTLRGVHQKAVQYLRKLLMDNGLPVEHCPSHILPVHVGDPMLCTKVSDELIRRYGHYVQAINYPTVPRGQEKLRIAPTPQHTPEMMDQFVKDLVSIWKELNLPLNDKRCGDECTFCKRPFLFKQLEARQKCNSECDKPYCPQLAECF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NAV3</accession>
    <name>A0A3R7NAV3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024712</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000882">
        <property type="protein sequence ID" value="ROT82126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NAV3"/>
    <dbReference type="STRING" id="6689.A0A3R7NAV3"/>
    <dbReference type="OrthoDB" id="10254973at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="135"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="216"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="315"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="568"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="697"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="790" mass="92561" checksum="8D2BD852603AA727" modified="2019-04-10" version="1">MSNLHNEFKTGNIFRIYIKDFLTFDEIEVTDYIKNGKDVSILETEIFVEGTSSNVVIKRQFDRKKKTVWFLQGKEVSKKVVETKIASLNIQVDNLCQFLPQDRVASFAKMNCIQLLEATEKAVGDASLYEHHDLLRSSGDKMKDLRAKVKELESQLEIAVKKNERLKDAVKNHELKNKLEKEIEQLQTQKLWFLFDVKRRVHMGLKANASEQKTALNKKRGELEPARKKIEKAKKDMVEYKKDIRNRTKFAETKQEEIDKLHKRYQQLEEALQDAQREYKGRELEEQQRMRELSDYRKHLDVLLVQLNNLPQVNDEETKKRLMELTRDIQEASQSMVRLESQRDEVVHSKKESERRIFSTERELVGLQDVARQRLELLNKTNAEAYRAAKWLESNADKFSAPVYPPLCTQLNIKDPKYAKYVEDRVSYQDLVAFVCESKEDMNLFKELMDKQKMRVNVVHSSPADMSQFQPKIPIENLKEFGFLNYMIDVVDAPPAILSYLCRNYSIYRIPIAEKADFDRVPVQLPYFYIGGERYSKAQSRYDKEWSTSIYPVKDARLLHITQDTQRIQQLRETINNSRDMIADAEEKLKQNKTEEHELTKNLEKLRNEKRVLHCRKEERKQMEQRIANKKNQIARHEKSSVNLEAEKAKMTKKIKETISMMIGSMTEQKKKMEVLAEVAVEHSKLMTQAAVTRTSLQILEEDLVSSEQALTTLQESIDRLTREQDAAKADATSTLQELLHSLGVRDYKDITNEIRERFRNSNLEETEQKLHQLEAHRDCLITANDSVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NBN1</accession>
    <name>A0A3R7NBN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cell growth regulator with RING finger domain protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000779">
        <property type="protein sequence ID" value="ROT82743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NBN1"/>
    <dbReference type="STRING" id="6689.A0A3R7NBN1"/>
    <dbReference type="OrthoDB" id="10251219at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030308">
        <property type="term" value="P:negative regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042496">
        <property type="entry name" value="CGRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15379">
        <property type="entry name" value="CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15379:SF2">
        <property type="entry name" value="CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT82743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="40965" checksum="284E79CE815BDFEB" modified="2019-04-10" version="1">MLPSPAFFACRRCVHSSALLTRVCVKNGKRIPPFPVSRLPFVPSLFPLLICFFSKVHLFCLTPFPSLPSSALTPSFPSQPSTPPPPYPSSPSSRTLLSPVLTAALMSAAEISNLCSALGVIICFVCMVVFILRLQGEDFIGTSVTHVAQPPVAQVAVQKVSVPFSIEIQDPSTASYNDIQLRVRSEVAYVRRSFWGVPSDQLHSLLNGTWPAFLRLIVEKPVVEADVVEEFYREDDNENADDTKHFQFKGNPQDLMLGSPPRKKYPLVVCVVRQDAHAEADPSNVGALISIIHIKDSECQVPTCILHQYLKQYSGQLTRLQALYTQGKTYISGPPTLPACLCLQHLLWEAKQLPHVPCKDTQLLPCGSREC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NMM9</accession>
    <name>A0A3R7NMM9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020068</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003826">
        <property type="protein sequence ID" value="ROT62103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NMM9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="45053" checksum="FFAD2785F37E8260" modified="2019-04-10" version="1">MAVFHPIFAHPAAPRSPPLLSLLVSLSLSIVSVILPLSLSIRLSLSHLLHLSRLSPRSPFSRRHPLTSCRRSLSFLLSSMYIVHLSISSLGPSLAHSSLLPLFLFNLSASLLSALSLLSLSRRPRSSLVFLAPLSAFVRLSHHRNLLSSSLRSLNSSSSLFLCFPCPLRDSFFSASLSPHPPPASAPSGHVSVLGSPLARACSSAQLRHSLPAGLELHYLIPSSPLFPTCIAIRPYCPPSSSPPPSPLSARSLASPPLLSPSPSPPPPLPPLPPPSHPLTYLPPFDPHSSSLLNSSPSLLIPLPLFPLRLTPLSPSIPPLPSLRHESLHPHSSLVHSLSPHHLPTHSSPSLLSRPSPSHLPPPSPPSSPLPPHSSLPLPPPSPLDTSPLHSLLLSSLPSHSLLPLPSPRHYLPLPLTPPLASGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NMS2</accession>
    <name>A0A3R7NMS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003781">
        <property type="protein sequence ID" value="ROT62182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NMS2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="51226" checksum="7A6B1A8B481D6B4D" modified="2019-04-10" version="1">MRYQIAPPPLHTFLLASLPFLFPSHPSLPPTPLLHLPISISLLIPFFAPPSSPYLHFLLPSLLRPSFISLSPFPFSFPPSPLLHQPPPPLLRPSFTSLSPSPSSFPPSPFLHLPISISLFLPSFYFHLPPPSLLLFPSPSSFLLHPSFTSLSPFPSSFPPLAPYLHLPPPPLLLPASFTPCFILPPLPLRLPVSFLFLPPSPLFPPCFSLPPPSLLRPSFTSLSPSPSSFPPSISISLLIPSFALPSPPYLHLPPPSLLRPSFTSLFHSPSSFPPSPSSFTSLFHLLLLPSFALLYLPVSFSFLLPPSPLLQPPCFNLLLLPSFAPPSPPVSNLPPPSSFALPFSFPSSFPPSPLLHLPVSISSSFPSFAPPSPPVHSPSSFPPSPSFTSLFHSPPSSLLAPPLPLSTSLLRPSFTSLFQSPSSFLLPSLRPSFTSLFQSPSSFPPSPLLHLPVSISLLLPSFAPPFTIPLSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NXQ3</accession>
    <name>A0A3R7NXQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">C-type lectin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_012144</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002540">
        <property type="protein sequence ID" value="ROT69640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NXQ3"/>
    <dbReference type="OrthoDB" id="418245at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051663">
        <property type="entry name" value="CLec_Tetranectin-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22799:SF1">
        <property type="entry name" value="C-TYPE LECTIN DOMAIN FAMILY 11 MEMBER A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22799">
        <property type="entry name" value="TETRANECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 10" id="KW-0430">Lectin</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018576773" evidence="7">
        <location>
            <begin position="16"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="8">
        <location>
            <begin position="120"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="9">
        <location>
            <begin position="241"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="9">
        <location>
            <begin position="434"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT69640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="504" mass="56755" checksum="B9D290BD013D0C16" modified="2019-04-10" version="1">MIFLFFIALAGGTQPERGISSCIRTTVLIGTSCPCNEAWCHELEKEIAGHAAEHMTGFCMPTYDAGLCYRMFTMQNSSQEICGCCIIQTRMLCSQENTSSNTSKDFTFGRLREVEEGLACGEHNITSPRFFTSPGYPLEKYPNKYYCWRRFRAWAPDYTIQVDCAMIHLRKDKNCQADFLLFKDGYSLEERLCGLLYNVTKVSETGAMNVLFDTNRRKKQVGFNCTVTAIELPCPGPFTKVGSECFYLSESGCVFGEARAFCLGLGGNLASPADVPALKDYVIGKGQTLAVWLGASDLDHEGDWQWFDGSPIKAEDWHWNAPNNGFGLEHCMVLRPDFDPPLNDAECDRPKKFVCDSHRTTRATGSGFDGSPIKAEDWHWNAPNNGFGLEHCMVLRPDFDPPLNDAECDRPKKFVCDSAAPLCISLPRLQRPVLRLSSFLDHEGDWQWFDGSPIKAEDWHWNAPNNGFGLEHCMVLRPDFDPPLNDAECDRPKKFVCEYDLLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P0G6</accession>
    <name>A0A3R7P0G6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002227">
        <property type="protein sequence ID" value="ROT71926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P0G6"/>
    <dbReference type="STRING" id="6689.A0A3R7P0G6"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="166" mass="19163" checksum="F7D702F0C78C11D7" modified="2019-04-10" version="1">MEEPVPNQDESISLDTAVFVFSLFDTGALLFLLVYYVITLSDLECDYLNAQQCCYRLNIWVIPKMVAHFLLSAVFLLTGHYYLFLASLPLAIFILREYIKVPKGNFGVYDPTEIHRMGQLKNHMRDAVIGLAYYLIFFFIYLYCLLTHLLRSNPVPKPDLSDDTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P1J2</accession>
    <name>A0A3R7P1J2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative myosin heavy chain, muscle-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002094">
        <property type="protein sequence ID" value="ROT72875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P1J2"/>
    <dbReference type="STRING" id="6689.A0A3R7P1J2"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin tail" evidence="3">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="153" mass="17454" checksum="8239A9DBB4C1E31A" modified="2019-04-10" version="1">MATDKAAAEKMNKQLQHQINEIQSKLDEANRTLNDFDATKKKLAVENTDLLRQVEEAESQIGQLSKLKLSLTNQLEDTRKLADDECRERATLLGKFRNLEHDIDGLREQLDEEGEAKADLQRQLSKANAEAQMWRAKYESEGVARAESSRQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P365</accession>
    <name>A0A3R7P365_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hornerin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007331</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001926">
        <property type="protein sequence ID" value="ROT74179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="609"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="656"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="685"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1523"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1555"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1590"/>
            <end position="1612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1618"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1646"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1669"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1702"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="878"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1731" mass="187259" checksum="3E7EC8FD1743DAE3" modified="2019-04-10" version="1">MLKPQYKVSLLAFPEVSLFFQRSLSWPSQIPEVSLLPSLSLLAFPEVSLLAFPEVSSWPSQRSLSGLPRGLSWPSEPSQRSLSLAKRSLSWLPRGLSLGLPEVSSSRGLSLVSLLASQRSLSWSSQRSLSFPERSLSWPSQRSLSSSSLLALSLLAFPEVSLLAFPEVSLLAFSLAFPEVSLLVQRSLLAFPEVSLLAFQRSLSWLRSLSWPSQRSLSWPSQRSLSWPSQRGLPRGSLLAFQRSLLAFPEVSLLAFPEVSLLAFQRSLLAFPEVSLWPSQRSLSWPSRGLSLGPRGLLSWLVSSWPSQRSLSWLPRGLSLGFPERGLSLGLPRGLSLGLLPRGLSLGLPEGLFLAFPEVSLLEGLSLGLPRGLSLGFPEVFSWPSQRVSLLPLSQRSLCWPSQRSLCWPSQRSLSWPSRVSLLAFPLSLAFPDLSLAFPEVSLLPRGLSLGLPRSLSWPSRGSKRSLLAFPEVSLLGLPEVSLLASQRSSLLAFPEVSLLAFPEVSLLAFPEVSPLAFPEVSLLAFPEVFPSILLLSWPSLGSLSWPSLASLHLLAFLEVSLLAFLVSLLPRGPSLSALSLFSLLAFSSQVISLGLLPVLAFLGLSLGVLAFLVSLLAFSSLLASLRSSLLAFLLSWPSLSFSGSWPRSLAFSWGLLCLAVGLSLGLSLGSLFLAFPGLGLSRGFLLSLGLLLELFLLPFSRCLFGLPGVSSWPSRVSLASWAFLQGSSLGLPEVSFSLWPSLRVSLLAFPEVSLLAFPEVSLLAFPESLSWPSQRSLSCLPRGLSLGLPRGLSLLSQRSLLAFQRSLSCLPRGLSLAFQRSLSWPSQGLSLGLPRRSLSLPSQRSLFGLPEVSLLAFPEVSLLAFQRSLSWPSQRSLSWPSQRFSSWPSQRSLSWPSQRSLSWPSRGLSLGLSQRSLLGLPEVSLLAFPEVSLLAFQVFFLAFPEVSLLAFQRSLSWPSSLLAFPEVSLLPEVSLWPSQRCLSWPSRGLFFSPRGVSLGLPRGSLLAFPRVSLLAFPEGSLGPRGVSLFQRCLSSSRLSLGLPRGVSLGLPRLLPEVSLCLPEVLLAPEVSLLAFPEVSLGLPEVSLLAFPEVSLWPSQRVSLASRGVSLGLPEVSLLAFPGLSLGLPRGVSLAFPEVSLWPSRGVFLAQRCLSWPSQRCLSWPSQRCLSWPSRGVSLLAFPEVSLLAFPEVSLLAFPEVSLLAFPEVSLLAFPEVSLLAFPEVSLLAFQRCLLGLPRGLSWPCVLFFQRCLSWPSQRPSQKVSLLAFPEVSLLAFPEVSLLAFPEVSLLAFPECLSLASSRGVSLAFPEVSLLAFPEVSLSWPSQGLSWPSQRSLSWPSQRSLSWPCLSSWPFQRSLSWPSQRSSFFSLGLPRGVSLGLPRGVFSWPSQRFSLGLPRGLSLGLPRVSLLAFPEVSLLASQRSLSGLPEVPLSWPSQRSLSVGLPEVSLLAFQRSLSWPSQRSLSLPRGLSLGLPRGLSLGLPRVSLGLPRGVSLGLPRSLLAFQRSLSGLPRWSLLAFPEVSLLASLGLSVGLLFSLAFGLSLGLLWVSPLAFSGVSLLAFSGVSLLAFSGGLFFLGSPFSSRGLSLGLLWGLSLGLLWGLSLGLLWGLASSLGSLFSVSLAFSGVLLLWGLSLGLLWGLSHGLLWGLSLAFSGVSLFSGVSFSGVFLLWASLWVSLLAFSGVSLLVFSWKASFVGDVHSILVFLLALLGVIRAWRGLRSWAHPGTNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P767</accession>
    <name>A0A3R7P767_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P767"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.110">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018654340" evidence="2">
        <location>
            <begin position="20"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="442" mass="48380" checksum="FB0CF2ACA663A9DE" modified="2019-04-10" version="1">MVAARAALVYLSVVALVGAATLTTHRPSGTTTPHAHESNNAHQSHEAPKNHSHSSSTEKSTEQALRDDEDETGNKTAPNTVEAAAPSFELQAVKRAGEAKSDRGSEETGDRDSEETGDRDSEETGDRDSEGKSDRNNGARYEEEGDLYTDVVNGSDDLEELPIPMAQSASKLALRKRRLKRLGPQQHPSTAHAHVPPGHGTPASSPQGKGFTRPDGTYVVNDEDGYCVLAYFKAEVTIYYADVKGDYQDAVPCRIPGSLRPRRRSKLVSPEDDSEVSGTCDRIGKVSEVVVGWKTFVLGLRFGLDEITDSCMSRFSLTYDLSDPEFRLSRPGGGEVTVMSKDNRKYWQTNNARSFRCLLLHDVPLTDSFNNSATLHFDEVASRPSPAATGLERPSTASTACTRRNGAGDPWCLRSPPPPSHHRFLRHLQVLQGQEVNYDTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9U6</accession>
    <name>A0A3R7P9U6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptidase M12B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_017232</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9U6"/>
    <dbReference type="OrthoDB" id="6365097at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1620.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041645">
        <property type="entry name" value="ADAMTS_CR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF281">
        <property type="entry name" value="PAPILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17771">
        <property type="entry name" value="ADAMTS_CR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01421">
        <property type="entry name" value="Reprolysin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19030">
        <property type="entry name" value="TSP1_ADAMTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018576451" description="Peptidase M12B domain-containing protein" evidence="12">
        <location>
            <begin position="23"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="13">
        <location>
            <begin position="83"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="432"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="758"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="882"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="758"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="772"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="910"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="931"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="957"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT64824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1233" mass="133331" checksum="2EE94C3792336D6D" modified="2019-04-10" version="1">MVRLATLIVFSVLLVTIGSTETAERSESRLKSNVIDLELLLSQLSKPDGPHDLPQDQMLLLQNQLPVKTNESASTPDTATGKRVLRLAVFSDDALLNHLSDLYPEDPLTATEKYITTGVLAIEKLMQQAVDEGVEFKIKLVQVGVWAEKGATPFNTNGLSSSNLLNFCEWASERKPGRGDPGYWHHAMMLTGKELFETTKDSLGVTFVGGLCHPRTSCSVVEANSFKAVQVAAHELAHSMGVPHDGEGAAARCPSEGFIMGQSLSEETFDWSNCSRDAISAFLKNDTCLEREEDGKGYRGLDHTQGGLPGQRYTADEQCALALGTSYRATPSKRSICEYLMCTNGVTTRGTHPALPGTSCGNNRVCVAGQCRAGGGGTRPPTTLLPGLLATLTNLPGLLATLTNLPGLLATLTNLHGLLTTLTSLLTTLTSNLPPNNPYKPPNNPNRPPNRPNRPSRPANKPVPFSGVEETDGNIVKKEKFPLATIPSELANIPMPYRCHFMPPFLHRYIGCGNYPNRNPHSPEAPGRTPGYLDTTAEIYEHSLDDEESKQMQDSPVRGENHGLILSDGAQNLSYGEEAKNSSITEGIPDYVISGELQQSLTFTGVEHSTHASQGQEILTPIQGLQNVSTTMNEIGDNQNSTHQVQPLPSTVQQVQEVIATTYQETPTTTTIQGVTKPPITTNSITKSPVIAYQGSDYDVTTHATNMFQMSAEQMAPTVNVEVVHPLTTENVTSAATPALGMGYSLTYNVTAEQVSTAEPATMEHQQAITQSTSVEEGTTTEPVTEPSPTKLPEQMSIEKSDTPQSTTEQPVVELTTDQRVEKLTSAYQIATEQPAFEQNTEEPDTKLITTEPPIKQVIAEQILTEQLGTEQTIIEQPHTENITAEEITTEHPAAETTTGEQITIKEVTIEQPTTEQSSEEITTEKSTNEQSTTPEPSTTKQNPAGEPPSVPMTATHAVSEQTFTKPVQNPEEDQSAKDNSEEDQSNTIFSVEDFNVTGSGLHFSIPSHLLHSFLGPVLMGSLAKDAPTPKGRLKDKHLFKESFGHQRNAFARIANLREGHHQAPVVAATAPTNTRAIRISPCSRTCGGGTRSVAQVCVKMDSPEVEVSEELCDGLPYSFSPFNQSCNTFPCSVPKWVVGPWSACSDWCGLGIQRRFVACGLPLVAGTSPLAAGRFLTPARCAGAHPTEVRLCKGPCVEVDCTVPGNALHPACRHLLKDTPLEKDHARQSSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD39</accession>
    <name>A0A3R7PD39_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">10-formyltetrahydrofolate dehydrogenase</fullName>
            <ecNumber evidence="9">1.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_014802</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-10-formyltetrahydrofolate + NADP(+) + H2O = (6S)-5,6,7,8-tetrahydrofolate + CO2 + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10180"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="1.5.1.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10181"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">In the N-terminal section; belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.6" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01002845">
        <property type="protein sequence ID" value="ROT67137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD39"/>
    <dbReference type="STRING" id="6689.A0A3R7PD39"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016155">
        <property type="term" value="F:formyltetrahydrofolate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009258">
        <property type="term" value="P:10-formyltetrahydrofolate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07140">
        <property type="entry name" value="ALDH_F1L_FTFDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08703">
        <property type="entry name" value="FDH_Hydrolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000002">
        <property type="entry name" value="10-formyltetrahydrofolate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.25.10:FF:000002">
        <property type="entry name" value="10-formyltetrahydrofolate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.170:FF:000002">
        <property type="entry name" value="10-formyltetrahydrofolate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000050">
        <property type="entry name" value="Aldehyde dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000008">
        <property type="entry name" value="Cytosolic 10-formyltetrahydrofolate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.25.10">
        <property type="entry name" value="Formyl transferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.170">
        <property type="entry name" value="Formyl transferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011407">
        <property type="entry name" value="10_FTHF_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037022">
        <property type="entry name" value="Formyl_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036489">
        <property type="entry name" value="10-FTHFDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 12" id="KW-0521">NADP</keyword>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 9 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="16">
        <location>
            <begin position="332"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="active site" evidence="14">
        <location>
            <position position="684"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="684"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="718"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>(6R)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>(6R)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="608"/>
            <end position="611"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="641"/>
            <end position="646"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="661"/>
            <end position="662"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="768"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="815"/>
            <end position="817"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="13">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036489-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036489-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR036489-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036489-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT67137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="913" mass="99887" checksum="D00698324752DAB2" modified="2019-04-10" version="1">MFACAQIYRRFSTSQSVLDRMRVAIIGQSTFAGEVYKKLVKDGHKVVGVFTVPDQGNREDPLATMAAADGVEVFKFKSWRKKGVALPEVLEKYLSVDPELNVMPFCSQFIPMEVINHPKNKSICYHPSILPRHRGASSINWTLMCGDKKGGFSIFWADDGLDTGPILLQREVDVDPNDTVDTLYNRFMYPEGIKAMAEAVTMVADGTAPKIPQPEEGATYDPMLNKKELCKVNWDQSAEGIHNFIRGLDSSPGAWTVKLFGSKMFTGSVSDGREVEIEGLSAPGIIHKDGLLLTGKDGQKVNVSRLSVDGKMMNASKYGAAAEAMEAIELTAEEQEVAGKLKETWKAILNIEISDDTDFFKSGAGSMDVVRLVEEVKEKAGVSLENEDVFMATTFQEFIQVMVRKMRGGDEKPVFEFDAVKMHVNNMDISFAHQLFIDGQFVDATGGRFLKSIDPATEKLICDVHSASKDDVDKAVQAAKKAFYQGPWGSMNARDRGALLFKLADLMDEHKEELATIESIDSGAVYTLALKTHVGMSIDTWRYFAGWCDKIHGSTIPINNARPNHNLTITKKEPIGVCGLVTPWNYPLMMLSWKMAACLAAGNTVVIKPAQVSPLTALKFAELSVKAGIPPGVINVLPGTGSVCGQAIADHADVRKLGFTGSTEIGQVIMKSCAVSNLKKVSLELGGKSPFIIFSDCDLDKAVRMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVARVIEECKKMVIGDPLNRGTAHGPQNHKAHLDKLLEYIDIGVKEGANLVYGGTRVDRPGYFLHPTVFTGVEDHMFIAKEESFGPIMVISKFGNGEVEEVVARANNTEFGLASGVMTKDISKALLVSEKLDAGTCFVNTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKTITFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDL3</accession>
    <name>A0A3R7PDL3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014386</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002803">
        <property type="protein sequence ID" value="ROT67531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDL3"/>
    <dbReference type="OrthoDB" id="6351141at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="36643" checksum="B127B0EFE6763C4E" modified="2019-04-10" version="1" fragment="single">WSGKPESVQGRMPSASSERREGSLRRRPPLRVVVAGQALAEAVGLGAGDGQMGHCGSASSLVRARHGDGMYATGYCLTAPSLLPEILCGKRDFLYIYCEQPTFFAFDCAQYPCATPCLNNSMGECKEASASTECSIQRLNGVYVPLDKAATSVFWWPGSANKLGMEGGTIDKYHDVDSVRKQWHQIIITSHEAVLQCGITSESLNLSLHCPEDLGDDYNEYEHFMSRMFVGSYRGHEMTSSYWALGCDVTPSWCPDSAECAIPATKEKKEVQWWMKLVLAVEVIFLVIGLVWLGNGILFQVRRKRTQKREFNRQQRPTGDNKVQETKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEW2</accession>
    <name>A0A3R7PEW2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000565">
        <property type="protein sequence ID" value="ROT84297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEW2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41321" checksum="93FE96A739D513FB" modified="2019-04-10" version="1">MLTLTSLSDIQSCSIIKRGFVPASPRQAGRRSQHESHMKILRRPIPRREARGAPRPRCPGGAQFTEYNFNLVDVCSSCVLTSAERLFRSKLVRERLWRRGILIQAGTRRGGGTRAVKELYDFSRGLLAKRVGRLRNLMGAPLAEAPGRQGQEGASSAIPWFHIPLLPLLSSLPLSTFLYPLSPSLSLSTLPSFPLYSPSHLSPSLLFFSPHLLSLLLPSPFSPLPFITFPPLPCPLIPFPISLPTFLSLYPFLHLLSFPSLFFTSHFLSLYPFLHPSLPSPPSPPSLPFSSPPLPPLPPLLIPLSPIPPLPPPPPSLPPLPFSPLSPFSPSPPPPSLLCLPFPPLPPLAPLLLCLEGGFRDNSPTYVKSRIARLLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEX7</accession>
    <name>A0A3R7PEX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003362">
        <property type="protein sequence ID" value="ROT63869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEX7"/>
    <dbReference type="OrthoDB" id="10489088at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018789307" evidence="2">
        <location>
            <begin position="22"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="44829" checksum="90C285FFB9105140" modified="2019-04-10" version="1">MRQIHIFLLVTWSYLFGGQRAHENVPARYRSPSKGQPAARPSLINETEQETFVMHIRITEVSVHSDEEEGRGGAAAPPRAKRGTCDADVVVPPNRTRFITTETKARVTLYFHPTEDFRYLSVILKLSNILDSPKIQVSFPSSHLCASDFSRWHELTVDAFELDVKNEVDKWAVRASVGSCSFIKASPYWYSLSTFKDLKIVATGASSWRLSAPGEDCRFTTTTAVPTQIALLPRHDFENAHHHDNANHNDYLSNDCQVHDTRNNYYLPDDCQTHDTRNNTTSPTTAKPTTRIATPTFPVTRRSNNTSPPTTAAKSTTTTTVRCQTPSLPQADDSTTSSRTTTTPGTTATTSTAVQLGQSTAGGRDKPEDLNHNPADTTDNVATDTTDNPGARRPAAAPDYHARSAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFI9</accession>
    <name>A0A3R7PFI9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003176">
        <property type="protein sequence ID" value="ROT64857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFI9"/>
    <dbReference type="STRING" id="6689.A0A3R7PFI9"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046351">
        <property type="entry name" value="UTP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="674" mass="75542" checksum="99897DC3E8737C79" modified="2019-04-10" version="1">MGEFTVHNVRFYDFEPKSIQCMSYEDESNRLALSRADGSVEIWNCKHRPFMQQVIHGDEDSSVEALAWCNGRLFSAGLHGFLLEYDLASCTVRSRTAVTGGPTWCLALSPNKQKLAAGTEDGYVCLFNVNENRVLYDKSLAKQEGRILSIGWHLSGNYIVTGSVNCVRLWSLKDGRVTRCSMGQTRGREIIVWCVAILDDMTIVSGDSRGKTCFWNSTLGTMTQYVQTHKADVLSLVICPEQKSLYVAGVDPTIVQVKLVQTGSKSGRKECWMRSLPRSIHTHDVRAMALTTNGKLYSGGVDTVLALSYYPPKTVIKYRALPHPGSISIASDAESILLRYKDHLDLWRLGHYEGNKKKPSGSFLPISQDRVKLLELQCKEDEVTEWSAISSSGKWIAYIVHGNHRLFHFNLPKDGKGLSLQRIKTMNESIKQCRQVLWIAEGKLASIISVTESEAEVDMELCLEEGHSVNKMKANSEGSILVVADNHEVITAFNLRKDTKSVLPKYSAPVTALGIHPVTSDVVVVYADMMVKEYSLQTQHYTPFCREFLSECPAELTKRNSVVHDVSFDVRHKNLVLLHDDSAIIVLNKAKSVSEPYVNNKPAKMKRRDSPARRMNGKIEKGKSTLCFTIARRPNQILHFSHVKNESVVSVELDDLQLLDKLPPTLKVKKYGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG96</accession>
    <name>A0A3R7PG96_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010858</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01002380">
        <property type="protein sequence ID" value="ROT70839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG96"/>
    <dbReference type="STRING" id="6689.A0A3R7PG96"/>
    <dbReference type="OrthoDB" id="2019940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF63">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT70839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="52958" checksum="63CC4616496C25DB" modified="2019-04-10" version="1">MTSYRISFSSSRGNPFVLSPSSYSLHSFSVLSLSPSRQNQKGKVSFSASEDVNPRYNIAAKKEVVDVELLPLKKEDFEDAKQLLKQEYWKSPEGAKLWEKNRNLEEKRPFAFNDLEANVWKGEDDLMGLKGKVEDLRTNDLKEDAGAIEDDLKLRRRRVKEVCKKYNLGPLAKPGSRPSIKHPPTPNYDVFYFDRNDGLAWCPIYKAASTTWLYNFILLGGLSDSYVQNTKEQVSHVARKLWPPLEYTQAEALKMSLKFMIVRHPFERIVSAYRDKLENLNIGKEHGIEHFYQKYGRKIVAKYRQEGHGPPPADRYSQDKDNPALPPPKGIEPTFEEFVRYLINTDLVYYADDHWMPYYLHCTPCLVDYDVIAKFETLERDQRYIIQKRKLEKKIEVSWKHLTKGKKTAETVKKYFATITKEQLLKLYEKYRIDFELFNYSIDDYLFYVKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PM92</accession>
    <name>A0A3R7PM92_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010579</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002342">
        <property type="protein sequence ID" value="ROT71112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PM92"/>
    <dbReference type="STRING" id="6689.A0A3R7PM92"/>
    <dbReference type="OrthoDB" id="9439903at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001049">
        <property type="entry name" value="zinc finger protein 319"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001289">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT71112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="138" mass="16091" checksum="1C1B1014A1DB972F" modified="2019-04-10" version="1" fragment="single">SFKCQVRQSVRQQGHLFIHKNVHAEVRPFGCDTCGRRFSQKGNLLRHSLLHTNEKPFGCGVCRKFFVQKAHLVKHVVVHRQRLAALKRCRRREALERGSSAEAKEGALRCKVCGLQFRRIFQLMEHLKAQHILGRERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNZ1</accession>
    <name>A0A3R7PNZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic prostaglandin E synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001430">
        <property type="protein sequence ID" value="ROT78105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNZ1"/>
    <dbReference type="STRING" id="6689.A0A3R7PNZ1"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="96" mass="10948" checksum="2C792CD547C52B6A" modified="2019-04-10" version="1">MRVGGSMCACRADTGQKEEGPYWPHLLKEKTKQHWLKVDFSRWKDEDDSDDEEGQNQDLEEMMRQMGGLGGGGDDRPSLDDLEDEDSDDDDLPDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPF7</accession>
    <name>A0A3R7PPF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008569</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002080">
        <property type="protein sequence ID" value="ROT73008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPF7"/>
    <dbReference type="STRING" id="6689.A0A3R7PPF7"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052242">
        <property type="entry name" value="Mito_3-hydroxyacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43561">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43561:SF3">
        <property type="entry name" value="HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="2">
        <location>
            <begin position="46"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="146" mass="16750" checksum="C34E0AF516C883C2" modified="2019-04-10" version="1">MNNLTGCFFFQQIIRIPETSNATYEAMKEWGKRMGKVSIQCKDTPGFVVNHLLVPYLFEAMAMVEREDAFKEDIDIAMKLGTGYPMGPLELSDYVGLDTLKFIGDGWMRDYPDEPMYRYPKILAKLVDDGKMGIKSGQGFYNYNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPN3</accession>
    <name>A0A3R7PPN3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dachshund</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002055">
        <property type="protein sequence ID" value="ROT73197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPN3"/>
    <dbReference type="STRING" id="6689.A0A3R7PPN3"/>
    <dbReference type="OrthoDB" id="6436112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052417">
        <property type="entry name" value="Dachshund_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12577">
        <property type="entry name" value="DACHSHUND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12577:SF6">
        <property type="entry name" value="DACHSHUND, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="251"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="44525" checksum="A685595EE5D68DA8" modified="2019-04-10" version="1" fragment="single">MSLNRGNFHTLGESGAAGRQSDSLARVGGETEEITERLKVKKQPGRAIREDRSREDRVLGLDRDEPGDRPTSPHKTNGYGESDVLNLSSKSDSRDDLSDAPTPRDDRDDKDEALSDAEDLDDKNDLSDREDFDYSERPSLHYTNNNNNLTSTANNNSSSGGGVASLVGGVGTLLTGTLSSSSSSSSVATPTISQCSALLPQGEDRLPPGLSGLAGLSMGGSGEVTPTPPHPPLSSLENLLGNIQNLLKVAAESVRHEEKQWNREKEHLRQEFMRQKEMRERLEKQLVEDEKVKLLYLRKLKKEKRARRRVEEELTEKLKRLSQYEPNAKDLLRAAAESLAKEGVKNAAVAAAAAAAAAAASGGSSSQGENPHHSPKSHQPQQQQQQQQQQQQQQQQQELQDVRTSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSX2</accession>
    <name>A0A3R7PSX2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myosin-2 essential light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_005324</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001695">
        <property type="protein sequence ID" value="ROT76077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSX2"/>
    <dbReference type="STRING" id="6689.A0A3R7PSX2"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032036">
        <property type="term" value="F:myosin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000082">
        <property type="entry name" value="Myosin light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF49">
        <property type="entry name" value="FI08416P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="11"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00069033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT76077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="78" mass="8883" checksum="93769AA7FBC8492E" modified="2019-04-10" version="1">MQTISRQRPVDTADDFIEGLRHFDKDGNGYISSAELRHLMTHLGEKLTDEEVEQLLAGQEDSQGNVNYEEFVRMVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTH9</accession>
    <name>A0A3R7PTH9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001631">
        <property type="protein sequence ID" value="ROT76622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTH9"/>
    <dbReference type="OrthoDB" id="10658003at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="18018" checksum="C109A8F70466CA61" modified="2019-04-10" version="1">MRAWWSRRLKREESRSPVCELCASGRDDQCSGKWPCRQAPTPNPSPPRKYRNNRSGSEWSNATQLTFISDGPADGPYSTRRTSFDSYGSSVSEESSESSGHFMEQLGTSTISYPPAGPPGSYLSPLELTYGHEDLRYAPDFDTILECDERSPRSDNAVSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PY20</accession>
    <name>A0A3R7PY20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003498">
        <property type="protein sequence ID" value="ROT63074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PY20"/>
    <dbReference type="OrthoDB" id="63112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT63074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="547" mass="60774" checksum="0A60741DB4B839D8" modified="2019-04-10" version="1">MALVNMPLPRLPLALARHQEALPLAPHRAAPPPTVPPTVISLKQMCSKYWLERVQYALRRDLPKPQVFRVQRFLEDLPRDLRTIMIHNALKAGGLHLQHGSRELAQINRALVLLTPEIVVYEPVYVSIPRPGADGVDWPLDIELLLYNGDGLMHLVLTMPPALPDAVRRVFTDLCRTCKKLRRVRIINANDDAITILTRHSRFVTHLDVSGSAGVTDEGLNRIIVNVLWGEGENSEVRLRHLDVGGTSVTQEGVCNLLTRLPSLTSLGSMDSIEALKMLDELSDGTTVTALEEVNARCVTVGTLQLLRRMCPNLTTINATLNCAGVTLNDLRLLPGLQHLRLTVREPFLLTPAALYEFAWSVGTQLVTLRVEGDVYWEADLGVLAGNCPHLEELALPAVTVPAKESITALTSTASIALAKLKVLEIDCMTGVGPKAWAKDFTLVRQGLVAALRKCLQLRRLVCRPTTLVENDLLDILAINRMQKLEVLELYNCVLGLSTARLIVDTCENLHVMKGLRTWRGLTLQDLVMLRKHTRGHRRMAELKILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYI5</accession>
    <name>A0A3R7PYI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001034">
        <property type="protein sequence ID" value="ROT81036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYI5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="616"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="616"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="708" mass="74280" checksum="0E5A7D3DD64CA3F7" modified="2019-04-10" version="1">MKNTKLASRFSLLASRFSLFASRFSPLAFSLSPSFSRLLASLLSLLASRFLLSRSLASCSRSLLSLFSSRLSPLSSRFSLRSPLPSGFSPLAFSPLSSRFSTLDSLLSLLASLLSLLASLYGPPSLARACVSPASMKNTKLASRSLLSLLSLLSSRFSPFSLSPLASRLSLLASRSSRSLSPLALSLLASLLSLSLALASLYGHPPWPGPAVSPASIRNTKLASRFSPLASRLSPFASRLSHLSSRFSPLASRLSPLSSRLSPLASRLSPLASRPSLLASRFSPSPPSLAFSLSLLASLLSPLASRLSPLAFSLASRFSLLSSLLSPLSLYGPPPPARACGQPRLDEETPKLASRLSLALASRFLASRLSPLAFLALSLLTLPLASRPHSLSPRFSPSLSPSLTLSSRFSPLTFSLSPLASRFSPLTSSPSLLSPLASRSLLASRLASLSLCPSLCFSPLSLSPLASRLSLLASLLSLLASLLSLLASLSRFSPSLLASLSLLAFSLPLASRALASLSLSLSSRSRFSPLLSPLASRLSPLPLASLSLAPRFSPLASRFSLPSTHPYGTRESLSSPFGQPLSHHPASLCPPFSTLAPPRCIPLVPPLKAPLAPAIPLPPHRQPLTPSQPSPHPLGTNIPLSPPLGTPLTIAPLPSPLAPPQPSPLHPLGTTPNILFPPRQPNHPLAPLGAPLSTTPTIPLRPPPLCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q5V3</accession>
    <name>A0A3R7Q5V3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MAGUK p55 subfamily member 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAGUK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002568">
        <property type="protein sequence ID" value="ROT69364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q5V3"/>
    <dbReference type="STRING" id="6689.A0A3R7Q5V3"/>
    <dbReference type="OrthoDB" id="65789at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11862">
        <property type="entry name" value="SH3_MPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.650">
        <property type="entry name" value="L27 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036892">
        <property type="entry name" value="L27_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050716">
        <property type="entry name" value="MAGUK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23122">
        <property type="entry name" value="MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101288">
        <property type="entry name" value="L27 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="102"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="200"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate kinase-like" evidence="6">
        <location>
            <begin position="332"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="61204" checksum="5F490F84541D2C07" modified="2019-04-10" version="1" fragment="single">VQDTLEEGVGVVEPVSSGNVKLVNQVRLLCEASTSAPSQELADLLLRPHLLALLETHDTIADRRHTGDAGTSNGYNNGINGCHDNATFMPEENGYPVDAIRMVGLRKRPDEPLGLTVREDESGYLVIARIMAGGSIDRQGLLHVGDAICEVNGVEINSLQQLHEEVAKCRDSVTLKVLPALHDPPAPNQVTSTLHPDATRAICYMRALYSYDPTDDTLLPTCPSQQPQDIGLKFEKGDILQIVDQSDPNWWQAQVVGSGSKRTGLIPSQELEERRKAFVRQEYDYVHKIGICGTRISKRKKKLMFSTKKSTDYDQAELLLYEEVARMPPFMRKTLVLIGSHGVGRRTLKNRIIASDPSKFGTIIPHTSRPMRELEVDGKAYHFTTREAMEADVRQHRYLEYGEFSGNLYGTKLDSILSVIRSGKMCLLDCSPALFISIGSLSPFPPPPSTLPSSAHSPLSRFFHLLVLDSLLFILSLLLPIYLLGLPFEIVFFSLLTFLSQHSSLSFSSFILSLSSLLCHATSIHKLSNSLSLSLLSFSPPNIPISQKLKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q625</accession>
    <name>A0A3R7Q625_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002557">
        <property type="protein sequence ID" value="ROT69515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q625"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="807" mass="88099" checksum="EB473DFF3B96611F" modified="2019-04-10" version="1">MAEDTPTSTHDTLHTHPKVTRTGYTTQGLHTYTQETRSYGGLSSKGMDYPGLQLSDSLDALDDPASGDGPPQVVAFQLKRLRSDDGSSTTAEEVWESLEQDSSGYVSCSEGFPAGGGASDAEPEFPAGSRSLRSIREDLAPAVSRETRSECHDALPLERETHEVGEVVASDGSLSEKASITEGKLATTSFTTKSAGGVKGEGNLPDREGEARRELGAAGRTESASSDSRRETAPSSRPPLTRARPLFGDDEPETPPASAPLAEDVAVRPKSASPSEKKSGEKEDSLSFKGRRNRKKGYASSSSLSLENPLPEIAEDPPAPQHVVVDLTGGGEHVSFVAVSVEEPEDPDSWDHEEALSMKIQTDLESQGDKMASRYLRSKGIRVPPPRHRSFGETVVNISAGEVDCEYVSEIESRKLNKSFNQSDAGEGGGRGRAEYLGHDNLAFVEDEQDAISQEENFATPEESDVGPVELPRRSSDPEVSSSAKSDEVKAEEELFRSASCGTELDKVLNNLSGEQSPVSGTPTLRKRSISRGRQESIHSEPDDTKAKETPDSAKYGDKKVRLRPTFFLGGEENSPSLFSKLVRNSPPVRLKRSESTKSHMSPMAYKEEGLSRSTSNIWEGAPRPAGEREFGRGGHHSRLPSTPTSPSVSVKGERRSEKGYLLQQHLYRNSRRNVQQKLHRQLSDSHHHDESSRVCPRDCFPPGTRRPPAIPNTHTTGTTTGASHSDTTTSRDTNYSDDTTHTDTNSTTNMYRNTNSAMHWNTLTNRNKHQIRTPCKFRKTLLSGASLTTARRKRGKPTWKGECQFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q8P0</accession>
    <name>A0A3R7Q8P0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010282</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q8P0"/>
    <dbReference type="STRING" id="6689.A0A3R7Q8P0"/>
    <dbReference type="OrthoDB" id="10251342at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.110:FF:000001">
        <property type="entry name" value="Protein MAK16 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04874">
        <property type="entry name" value="Mak16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="6">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="325" mass="38458" checksum="1A91D28A2DC7E735" modified="2019-04-10" version="1">MQQSDDVVWTIINKSFCSFKISTISQKFCRNEFNLTGLCSRSSCPLANSQYATVREEKGIIYLYMRTAERCPFPAKQWEKVKLSRNFVKALQQIDENLVFWKKYFRQKCRQRLLKITQYLTRMRKLKLGRKKKLIPLRRKQEVRLKRREEKALVAARIDNAIEKQLLQRLKEGTYERIYNFPQEAFDVRVDGEEVESDIDEVEYDEDREEEVETDEDVEGQLEKELSSDEDDSGDEEEDDEETREFVADFDESDEEDFESAADRLGDISEDSDEGSDDDDEVDDKEEERRKVMKAKPKVIKRRGKAQLEVEYEEPETAKKIRLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QC16</accession>
    <name>A0A3R7QC16_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001932">
        <property type="protein sequence ID" value="ROT74123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QC16"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018683108" evidence="2">
        <location>
            <begin position="18"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="263" mass="23378" checksum="FBDD466DF324BE2A" modified="2019-04-10" version="1">MRRSIAVLGLLVGAAYCFPGRISQSYGAPTVGFSSSGGHGSSFSGGSHAGGGSGFGGGRGSSFGGGSLGGFTGGSHAGGGSGFGGGRGSSFGGGSLGGFTGGSHAGGGSFSSGSFGGGSSGTSAGLSTSYGAPTSNFVSSTGGGFRGTGSHGSGSFGSKFSSGSQGSGSFGSGSHGAGSFATSHGSGFGSGSGSFGTGTHGGGSFGTGSHGGGSFGTGSHGSGSFGTGSHGGGSFGTGSHGSGSFGAGSHGSGGLSTSYGLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QH55</accession>
    <name>A0A3R7QH55_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate sulfotransferase 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002829">
        <property type="protein sequence ID" value="ROT67246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QH55"/>
    <dbReference type="OrthoDB" id="6138663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="360" mass="41788" checksum="F7404B18CA632553" modified="2019-04-10" version="1">MFLVVSELTQSDDVIKAQVKETPGSRGLMNNTMNTKLVGVLVEQRQNIEQQMKGYKFSREAQRKPPEGSRAGGRRSTREKCHCHFLEVRIHFHRIPKKCGVVSSHPGTFYHYEPLHDFGVKQIRHGEEAAQAVRNLRHLLDCEYGEMEHLIEHGRSFKCVFNQNKALWSQCKTLPDLCRKPEFLSPFCSLFPFQSLKTVRLRLNLTEELLEDKKLGVRLLYLVRDPRGTLHSRRNKNWCSRKDCNDPETLCKDLVRDYITASVFRRKFPNSFRAVRYEDISFNVFHETKELLDFFRLDFHPDIQKFLQTHTARSKGNAYSTFRDSKAAPPSTGRRRCPGKRRSGSRACARRPCGCGVRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QI73</accession>
    <name>A0A3R7QI73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001560</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001199">
        <property type="protein sequence ID" value="ROT79720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QI73"/>
    <dbReference type="STRING" id="6689.A0A3R7QI73"/>
    <dbReference type="OrthoDB" id="6380591at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000017">
        <property type="entry name" value="Down syndrome cell adhesion molecule b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF14">
        <property type="entry name" value="CELL ADHESION MOLECULE DSCAM2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="23"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="247"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="346"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT79720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="44363" checksum="2DB7236AA6291E0C" modified="2019-04-10" version="1" fragment="single">MASSHIQVVSRIPYKTFYHSPTPRTAEQNRIAHEIQVSAHPPVQTVSAGSRVSVRCRVQGSPVAEVRWYKDGSPLHTHTHAHLMLQGRDTLVITGVGERDAGMYQCVAANSLGEAQASSQISIRDSVPSLRHTFIEQTLQPGPPVSLKCTALGHPTPVITWTLDGRPLTPSSGHYGGQRVSVGAWVDVGGQVVSQVNISSAGHMDGGLYACAAANSAGRAEHSARLNVYGGWRGDGEAWEGLGDWMPSFVSVASAVSRTPSNVTVVDGSEATVVCPVAGYPIKSVTWTLHGRPLTPKPRRSPRADGSLVFQSVEAEQDVGLYTCTASNAQGRTATASFILGVLKPPVLAELKFPAGLVEGMRFSLSCSLLSGDLPISLRWEKDGRPLPRDPVLTETHSQFFTNLVFTDIRGRHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJU9</accession>
    <name>A0A3R7QJU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative methyltransferase-like protein 24-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002519">
        <property type="protein sequence ID" value="ROT69785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJU9"/>
    <dbReference type="OrthoDB" id="6348698at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="108"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="335" mass="38618" checksum="D7CDCCC53686994A" modified="2019-04-10" version="1">MIVISTQSQAVKNPRRVPSSRNLQTSQQVTNFAMTLLMGLILVVAVYFAVAKFQTHIPEYEATLKEVCRTSSLPRLQYKGVESFFEYLLNPDKSFCTSWVDFSKEGETESRVRRDSHYGRYVCANASDDGVGESCLVYYFTVVDDEQFKKDMDKLTCHVHEIVDKLKKEVEESEKSPRRHPWQISEISYDRVLPGGSVKRRRSLKDIVTSLGHVGRKVRFLRADLHGQEWTLLRQVVMNHDIINVHQISIGLHIPLSVNRLTMEERRRYFEDLYQVFKGLACLGYKHVRVEAIETDSSRLVVPEMGGATLPSFYEVHWVKTAPQASGSNDHYVYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-05-29" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLF0</accession>
    <name>A0A3R7QLF0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-arrestin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002333">
        <property type="protein sequence ID" value="ROT71189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLF0"/>
    <dbReference type="STRING" id="6689.A0A3R7QLF0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF17">
        <property type="entry name" value="KURTZ ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12644" checksum="11579EFCABAF3227" modified="2019-04-10" version="1">MYDCIITDSSQKENLGIIVQYKVKVKLNLGPLVGDLVAELPFTLMHPKPEEEPEVNNKPALPPASSPTQDPNSAPAVDTNLIELDTDGTTCYADQDDDIIFEDFARLRLKGETEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLJ3</accession>
    <name>A0A3R7QLJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002315">
        <property type="protein sequence ID" value="ROT71298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLJ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="40434" checksum="4FCA5D966F76B91E" modified="2019-04-10" version="1">MLVCLHSAREAQGSKQSCFLGGVGISAVLESSFLFYSPQSANSSTTPSNTTMPATPKSTIITTHNKTTITISTTTATKPPVATSTTTAVLSTTTTAVASRQDAGLLNMPVTETKKNHAYAMAPSAMSAFITSGSAVPVSAMAGGSAVPMSAMAGGSVPCLLWLDYCACVYHGWWIYCAYVCHGWWIYCACVYHGWICATMAGSTVPMSAMAGSMSAMAGGSTYGSAVPMSTMAGSTVPMSAMAGSTVPMSAMAGGSMSVACCAYVCHGWFYCAYLILLCLLDLCHGWIYCAYVYHGWWIYCAYVCHGWWIMSTMAATVCYYVYHGWIYCAYVYHGWIYCACVCHGWIYALCLHGWIYYHGWILLCLCLPWLDLLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QTG2</accession>
    <name>A0A3R7QTG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001509">
        <property type="protein sequence ID" value="ROT77582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QTG2"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="467"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="60156" checksum="AF124F130F460B06" modified="2019-04-10" version="1">MSDVTRNYLPSVFVQSSYPLSPFHPLSLSHSLPPSYTFSPSLSLTSLSTHSIFTSLSHSPSIHNPSHPLSPSSSLSLSSSQSTLHPSSSLPLLSSLNPFYPYIPLILFSLSPLLAHIPLNPLHPTPYLSLPLSSLSPSHSSQLLNPYIPLTSSLSSHPSLPFYPYIPLLFSLPSSLSLSSLSTHSILTSLSSSLSLSPLCPSHSLHLYLPLPSPLIPLNPFYPYIPLILFLPLIPLNLLYPYIPLILSLPSRLSPSHPSQPTPPYILSPSLPLTPPLTLIFLPLIPLYPYIPLILSLPLIFFLPLIPLNPLYPYIPLILSPSPLSPSHPSLSLHLLSPLIPLLPLIPLLPLLRRVGPPRRGVSLSGRPSRDETCGARPWSGTLAPVTPVAAMHLGDLQSSKPLNARDCLFLGKHAFNKGYYDKAIEWFEAALERSGSEEVLTAPKDEIEPFLQAAIKVHDDVLEKRGPRGTDWQTKALPVDKTLASKPKLPRRNAGLRPQIALPADRARGGEEHYNSVSTRESLGKGYAPPVERTQRFCTGGTEESPSSGKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QV39</accession>
    <name>A0A3R7QV39_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001974</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001260">
        <property type="protein sequence ID" value="ROT79307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QV39"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="111"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="42329" checksum="53CD9D38F182267D" modified="2019-04-10" version="1">MNTLHLNLNTLPSLHYYKLHSISFKHFLSFPPSSPLHSILLPLHKPRPLPAARNPQPSGDHPRSLKTSPESLSMPKTRASMCDLYINIGPRVVSRLGSSRVGGGGRDEGPVEWDKRARRGRSGRGERAPRIGVGGGEGNREPSPEAVAVKEVPAAEVVQEVAPAAEAVEPSEIARLHLILPPQGRHLTATGVPLVDLFSLPHTGLKKLVERASAWVYGVSRSGLSSVHQHEEAATPHALRSVPGLPKLMGLSLIPAAVLMTCHGTLDLQTWLCRHLELDEYLQILLSPSTTLHGLQTEGFTHNDLKSDNVTADERYVPTLIDVGLVSPKNGRPYKSNAMREAHDVESERASRHGHLAPEIYREELVPAPASPPSARSCTGPTGYLSSSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJ44</accession>
    <name>A0A3R7SJ44_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Cell differentiation protein RQCD1 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_018957</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003476">
        <property type="protein sequence ID" value="ROT63203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJ44"/>
    <dbReference type="STRING" id="6689.A0A3R7SJ44"/>
    <dbReference type="OrthoDB" id="1183224at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000037">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007216">
        <property type="entry name" value="CNOT9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12262">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04078">
        <property type="entry name" value="Rcd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT63203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="320" mass="35751" checksum="8397127FD1DA9E9B" modified="2019-04-10" version="1">MIESISATFGNKELHLMQGATPGQRFLGTGSGITSAERDKIYQWIIELANPDTRENALLELSKKRESVPDLAPLLWNSFGTIAALLQEIINIYPAINPATLTAHQSNRVCNALALLQCVASHPETRSQFLAAHIPLYLYPFLQTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEIIPLCLRIMESGSELSKTVATFILQKILLDETGLNYICQTYERFSHVAMILGKMVIALAKEQSARLLKHVIRCYLRLSDNPRAREALRQCLPDQLKDQTFGACLKDDKSTKHWLQQLLANLESTAAADHRITLPPLAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJQ0</accession>
    <name>A0A3R7SJQ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003361">
        <property type="protein sequence ID" value="ROT63880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJQ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="784"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="801" mass="92878" checksum="4139F6149A69D01D" modified="2019-04-10" version="1">MAMRKTGKGRALTAIQHGGKGRVSCVAAESDVQRGVLQSPLESHRIRQSESHRIRQSESHRIRQSESVRIRQSESHRIRQSESEVPEVESHRSVRVSPTESRQRFRQSDPESVRVSPTESVRIRQSESHRIQSEVRIRQSESTGQSESTVIRQSESVRESHRIRQVSPTESVEVRESSRVSPTESVRVSPTESVRVSPTESVRVSPSDSVRVKSTESVRIRQSESHRIRQSEYVRIRQSESHRIRQNPSGVSPTESVRIRQSESHRIRQSESHRIRQSESHRIRQSESHRIRQSESHRIRQSESHRIRQSESVRIRQSESHRIRQSESPEPSEIPVSPSRIRQMSPTESVRVSPTESVRVSPTESVRVSQIRQSESTEQSESESSEVSPRIPSEESHRIRQVSPTESVRVSPRIRSRVSPTESSHRIRQGESHRIRQSESHRIHQSESHRIRQSESQRTVRVSPTESVRVSSSESVRVSPTESVRIRQSESHRIRQSESVRIRQSESHRIRQSESHRIRQSESHRIRQSESVRIRQSESHRIRQSKSESVRSQSHRIRIRQMSPTESVRVKSVEVHKSVRVAHTESRQSESHRIRQSESHRSRQSEPHRVVRSESHRVRQSESHRVRQSDHRIRQSESHRIRQSESHRIRQSESHRIHQSESHRIRQKSVRVSPTESIRVSPTESVRVSPTESVRVSPTESVSESHRIRQSESQNRQSEPTESSEVPPQRESQSESHRVRVSPTESVRGSPTESIRVSPQNPSEIRQSESIRIRQSESHRIRQSESFSPRVSPSVPQSPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SM33</accession>
    <name>A0A3R7SM33_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_015384</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SM33"/>
    <dbReference type="OrthoDB" id="9996086at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="68"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT66585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="42645" checksum="7FBC081A62BF9693" modified="2019-04-10" version="1">MSSWNNPNPVTQLESTNPYGNYTVVDTAPKEILHMVHEHWYQFPPMNPLWYGLVGFWMVIMGCLSIAGNFVVIWVFMNTKSLRSPANLLVVNLAFSDFLMMLTMFPPMVVSCYWQTWTLGALFCEIYAFFGSLFGCASIWTMVFITADRYNVIVKGVSAEPLTSGGAMLRIAGTWFFAFAWCLPPFFGWNRYVPEGNMTACGTDYLTESEFSKSYLYVYSVWVYIFPLFYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFMAWTPYFVINWGGMFNKPMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACNTDGRDGGGSDAGSTATTAENNEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SR48</accession>
    <name>A0A3R7SR48_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative carbonic anhydrase-related protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010196</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002291">
        <property type="protein sequence ID" value="ROT71480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SR48"/>
    <dbReference type="STRING" id="6689.A0A3R7SR48"/>
    <dbReference type="OrthoDB" id="5978072at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF208">
        <property type="entry name" value="CARBONIC ANHYDRASE XA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018677142" evidence="3">
        <location>
            <begin position="20"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="355" mass="38223" checksum="DAB3DDE8B3995830" modified="2019-04-10" version="1">MKGHLARVAIIASLHLVSANYQQEPEEVVFDWSSWWSYDGISGPGFWGIINRRWRLCSDGRRQSPVDLATAAVVYDHTLSRLDLASHKIDGTLSNTGFGLRWTANAGQTWGVTGGPLHYAHTLTHAVLRWSNASPATSTVGSEHSIEGQFFPAEDCSVVFHTSCPFFTLPPNYSPISSPPSSSTSPSPSLPTSPPPYPPPSPPTFPPFPIPSSISSSTSLSKVSSLSHSPFNSLTSFLPLTPPNPLPLPGPLLSFSSAIPLHLLSLTCSYNSHHSSLSLFLFSPFPMRVVSFSLSPLPLPLPLSLPSLLLLTLHNLCTPLTSIPHHLPQSPTVIASRLSLSLSLSPYSLSLLDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSM5</accession>
    <name>A0A3R7SSM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Neuroblast differentiation-associated protein AHNAK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008332</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002049">
        <property type="protein sequence ID" value="ROT73242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSM5"/>
    <dbReference type="STRING" id="6689.A0A3R7SSM5"/>
    <dbReference type="OrthoDB" id="8058206at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043484">
        <property type="term" value="P:regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052082">
        <property type="entry name" value="Myelin_sheath_structural"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23348:SF16">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23348">
        <property type="entry name" value="PERIAXIN/AHNAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="341"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="509"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="604"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="691"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="828"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="883" mass="91595" checksum="8F43264C047E11E3" modified="2019-04-10" version="1">MKFGPCFGKGKDVDVEGEYKPGKVEVKGPSVSGEVGAASPEMSGDISVESPEAKIKGEKPKSKLGSCFGKPKGPKVEEISAEISAEQPKAKIKGEKPKSKLGSCFGKSKGPKVEGEYKPSIDVEGPEVSGEVAVPSAEVKGDIKVDSPDVKLKGGKPKSKFGSCFGKPKSPEIEGEYKPGKVSVEGPEAEAGVSVQSPAIKGDVDLESPEIKVKGSKPKTKFGSCFGKPKSGKLEGEYKPGRVDVEGPEVSAGASVKRPDIEGEIDIESPEVEVKGKKVSGKPKAKLGSCFGKPKEPKVKGEIDIEGPRVEGEVPTGKAEVDVKGPEMKVKNKKIDIDADVEPGSIKIRPEKPSMGGKISVEGPSIDVEPSVKVKGPSMPEVPELKGHLDVDADLPDFEPSIKIKGDIPDIPKVEAEIGGKADIPEIEIKGNVPALPIEASVDAPELKVEGELPKLKTEGDIDIGINVPSISGDIKGINIETPEFPSGKIEGDIKGDLPSIDIPKAEVSLPAGPELPSAEIKGELKGPEISGSAQLPKAELKTKKAKLGPCACLGKSGKIGKEEPYMAAEAGGKVSGEVEGVDVSVEGPKGSVGVDVESPEIKGKKVKASGKPKMSLGSCFGKAKPPSARGDISADAGVEGTISAEPHIKVEGAGIAGPSADITLPEGKVEADIESPEVKGDVDLESPEIKVKGSKPKTKFGSCFGKPKSGKLEGEYKPGRVDVEGPEVSAGASVKRPDIEGEIDIESPEVEVKGKKVSGKPKAKLGSCFGKPKEPKVKGEIDIEGPRVEGEVPTGKAEVDVKGPEMKVKNKKVKGKSAPLCASCIGKASPPDVDIDADVEPGSIKIRPEKPSMGGPELPSAEIKGELKGPEISGSANYQRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSQ6</accession>
    <name>A0A3R7SSQ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSQ6"/>
    <dbReference type="OrthoDB" id="6351383at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10773:SF19">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10773">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="586"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="728" mass="82775" checksum="E55DA846CC6DD094" modified="2019-04-10" version="1">MAEPAPEAAGFAQDLFSPLQFCEVVQEGQGSHHHVKDEPRPQQQAQLGTPHSSAPVTSMSQLMQQQLSVQQQAQSMAQRQMMQHQQQQAQQQAQQQVQQAAHQAQQQVAQQQAQQQAQQQAQQQAQQQAQQQAQQQAQVQQQVQQQVQQQVQQQAQVQQQVQQQVQQQVQQQVQQQAQVQQQAQQQVQQQVQQQVQQQVQQQVQQVQQTQQQAQVQQQVQQQAQVQQQVQQQVQQQVQQQVQQVQQQTQQQVQQQAQPSTQQMMQSQQQTPKQQQLQQQQQPGQQQVQPSQPQQQVQMAQTAVNNVQLVNGLQMPVAVQHPNTAKTPPSSGVTPGAATASPPLIVFTGIVTSEGAPVSSANTSSTSTANGTTSGTSSSDVKPVPVKRTWRRPWKKKKEREKKQPVKKARRVKRKRVVVPKKNIIHIDPRNGPVIDTTITQIKRESEEAINQLKQKRQRIKLNRNSGREYVNRLGKVVGARMIGSPCNCPLKCWERMGSKILEIFNNFWDLSDFNLQNSYLFTCLKLCDVKRRYTKKPAEESRRQNTFEYFVRISGKHLRVCKRAFMSSHGLTSDKRLRTLFHQMKDGALVPEPDRRGKHLRPAKSPNQMSPTQTIEQCQGNNKAKKPRTVKKKQNNKQENKPMYTPPPPPMGHIHPHCTPPPPPAHTTAMQEPPHAYIPNGDIYFPGHYLEPHQSMAPPPMNQIPSCQKMLEAPAYFMAGMKENTFHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ST92</accession>
    <name>A0A3R7ST92_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001951">
        <property type="protein sequence ID" value="ROT74019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ST92"/>
    <dbReference type="STRING" id="6689.A0A3R7ST92"/>
    <dbReference type="OrthoDB" id="66977at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050621">
        <property type="entry name" value="Tudor_domain_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948:SF29">
        <property type="entry name" value="FI02030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22948">
        <property type="entry name" value="TUDOR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="58"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="217" mass="24721" checksum="59AC584ADC086954" modified="2019-04-10" version="1">MPKPSDRTWRVHVTHVVTAGHFWIVSEETSALKNLNHIHSAIQRAVEQNQAVFIPESEVKPGIVCLAKFTDSDGMSCYYRARVDEVYTGEDNGVRAQVFFVDFGNTDVVKAVELRRVPGSLMLAEMLAVECKLAQVKPASDNKWLDEATEWFRSHTLNKDFIAQIYSVVHKIMRVKLMEVESGDFLSVNRRLIDLQYAVKAEEYYLSRSVFACFSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWC8</accession>
    <name>A0A3R7SWC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_002881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001387">
        <property type="protein sequence ID" value="ROT78403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWC8"/>
    <dbReference type="STRING" id="6689.A0A3R7SWC8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018578176" evidence="4">
        <location>
            <begin position="20"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="495"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="206"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="328"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="345"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT78403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="549" mass="58112" checksum="8539FF6A73980555" modified="2019-04-10" version="1">MLAWQSVGRFSLPVRVVLALPPLPGLEKTRDALAREGSVWGRDRHRATLETRIDTCQSHLSQHLLSISHRSPHPRSISRRIPHHILHSIPRSISRSTSLILHSKHLSQHASSQHLLSISLRIPILHSIPRSSISLAASLAASLAASFTASLAASLAASFTASSQHLSPHPSSSPHPSQHPSQHLSPHPSQHPSQHLSPHPSPHPSQHPSQHLSPHPSQHPSQHLSPHPSQHPSQHLSPHPSQHPSQQHLSPHPSQHPRSIAASFTASLAASLAASFTASLAASLAAILHSILAQHPSQHIFAASFTASLAASFTASLAASLSHLSPSFTASPQHLSPHPSPHLSPHPSQHPSQHLSSHLSPHPSQHPSQHLSPQPHPSQHPSHPSAASLAASFTASLAHPSQHPSPHPSQHPSQHLSPHPSQHLSPHPSQHPSPHPHASLAASLAASLAASFTASLAPSPHPSQQHSIAASSPHPSQHSISRRIPRRSISISRRIAASLAASFTASLAASLAASLAVLAASITASLAASRPVREMKRSGAGSTCQRRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBG2</accession>
    <name>A0A423SBG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004124">
        <property type="protein sequence ID" value="ROT61526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBG2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="44029" checksum="1DDF4E2D64E7307C" modified="2019-05-08" version="1">MLSLVSFSFFLPLSFHSLFSSLFPLFLPLLYPFTLFLPFCLSPFPSSLHQALPARLSSLSFSPLSLSFSLLSSFCFFSPLLSLCSSFLFLLVLFFPLPPPPSLLPSSSFPPLLFPLSSLVLSFLSSSPFLPSFPLLSFLFRPLSSSFSPLSLLLPSLPFFLLLSPLLFDSSRGASSLLPSPPSHHPPLPPSLLPLPHPTNTITTHTLHTSSGSAPEGKLVWDDRCLPFLFPSPPSLSPPPFLPPSHSPSPSSLLFYRPPSLSSLFFRRPPSLSLLSLFSYSSFMPSLFFSFFLSSPFFLPPLFCSSLCHSLISPSLPPYSYSFSSPLFPLIYLHLLPLPLLYSSFHPIPYSSSPLLYSSLCLLPPLLSPFLSSLSPFPLPYPPISLSLPPSPLPPPPPPPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDJ5</accession>
    <name>A0A423SDJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ovochymase-2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019889</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003742">
        <property type="protein sequence ID" value="ROT62277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDJ5"/>
    <dbReference type="OrthoDB" id="6345791at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019509275" evidence="2">
        <location>
            <begin position="20"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="27"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="17248" checksum="39D9FBE59F8654D2" modified="2019-05-08" version="1" fragment="single">MRTLGECLVLALVLSGAWGGVQRESRIVGGPRSDWGQFPMMVAVLTRPLIGTSKLLCGGTVLNDNHVLTSASCVMDHTALGLKVMAAGLDLLGSAGYEEYKNIQHVFIHEAYDPVTKTNDIAVLRTGQNFVFVEGLIDPTVLPEGRPGACERCLRLRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SER3</accession>
    <name>A0A423SER3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Crustacyanin subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_019481</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003566">
        <property type="protein sequence ID" value="ROT62668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SER3"/>
    <dbReference type="OrthoDB" id="6332976at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018825046" evidence="3">
        <location>
            <begin position="17"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="5">
        <location>
            <begin position="48"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT62668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22539" checksum="A9730B0F8DA0763F" modified="2019-05-08" version="1">MRTSLLCLALVAVVAADRIPGFVVPGKCPAVDERMLYSQQKPNYQRYAGTWYEIALTNNPYQLIKQCVRNEYTYDGTKFNVRTTGTDAQGNAITRKGQVLPNPFGEPHLSVDYEESWMAPYVILDTDYENFSCIYSCAGHNFGYYADFAFIFSRSPTLADRYYRRCEAAFMNIGVDPSRFSKTAQGASCSYNTNYRSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEW4</accession>
    <name>A0A423SEW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003553">
        <property type="protein sequence ID" value="ROT62767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEW4"/>
    <dbReference type="OrthoDB" id="10059697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="3">
        <location>
            <begin position="122"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="47477" checksum="5E6F212AD0F7639B" modified="2019-05-08" version="1">MGSEPIPQAQEGDNDSPSEGEFLDNEFDSFDACLDFGYQAREFFVLPDTPALDKAHQQDTSRVASAGGDTVSNQPAWTQLPLDHLTADQPEDDPDLTTMDPRKMREQQLQDPTCNDLIRALRTYQNLCNSWYFPNMLRQSREYVARCPVCQCRKGSAVRVPMQGHPPPEAPLVMVSADLMDLRSSSRGYRYVLSIIDHHTRFLQLARLRDKTAERSNGVVERSNRAVKDALAALVQRAPSQWPIHLPAVCLALYMAIHRSVGDQPLYLLSGRMALFAKGLTNDQTPDEGLMVKRLSDACHLAVEVSLKTRETNKAYYDQRAKATPTFEQGSLVVRKVEGTRRPLGDSWLGPGRIVRQLGPVTFDVLDLQEPYCAVRVHANQLKSYLPPSELDFAEEADQLPRPVPVAASSSVVTLIDELTSESAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH75</accession>
    <name>A0A423SH75_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Growth and transformation-dependent protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_018500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0389 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003414">
        <property type="protein sequence ID" value="ROT63598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH75"/>
    <dbReference type="OrthoDB" id="8193498at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009432">
        <property type="entry name" value="DUF1075"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13674">
        <property type="entry name" value="GROWTH AND TRANSFORMATION-DEPENDENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13674:SF5">
        <property type="entry name" value="UPF0389 PROTEIN CG9231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06388">
        <property type="entry name" value="DUF1075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT63598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="166" mass="18369" checksum="338FCD80758DF66B" modified="2019-05-08" version="1">MALRGTLARLPALRSSVLTTSPRILAVPARQTHSTEERLQVAPAVGAAVCSSAIPVGKLGLRDHHINRLEKYLLVWGGKYNSIADVPDLVSQDTLERARNKARIKINIWMGVATLLGCMYMIWSGKKAHREGQSLLAMNAEWHRRVNEEARLAKGEKNRLGDLADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKV4</accession>
    <name>A0A423SKV4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-galactosidase</fullName>
            <ecNumber evidence="10">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_017177</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01003173">
        <property type="protein sequence ID" value="ROT64877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKV4"/>
    <dbReference type="STRING" id="6689.A0A423SKV4"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019377">
        <property type="term" value="P:glycolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009311">
        <property type="term" value="P:oligosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000032">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000070">
        <property type="entry name" value="Alpha-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000111">
        <property type="entry name" value="Glyco_hydro_27/36_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035373">
        <property type="entry name" value="Melibiase/NAGA_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF86">
        <property type="entry name" value="ALPHA-GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17450">
        <property type="entry name" value="Melibiase_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00740">
        <property type="entry name" value="GLHYDRLASE27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00512">
        <property type="entry name" value="ALPHA_GALACTOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0458">Lysosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019074041" description="Alpha-galactosidase" evidence="11">
        <location>
            <begin position="22"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha galactosidase A C-terminal" evidence="12">
        <location>
            <begin position="315"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="50289" checksum="F97E44868DF22BF5" modified="2019-05-08" version="1">MTAARLLALTVALVCSGGVQALENGLARTPPMGWLAWERFRCNTDCVNDPHNCISETLFMQMADILVSQGYRELGYNLVSLDDCWLARDRDSRGRLQADAHRFPSGIPALSDYMHKRGLKFGIYEDYGNFTCAGYPGILGHLQKDAETFAEWGVDYVKLDGCYSHPTDMDRGYPEFGYFLNKTGRPMVYSCSWPFYQIYSRMKPNYSAIINTCNLWRNFDDIQDSWESVQRIIDYYGDNQDEIVPNAGPGHWNDPDMLIIGNFGLSYEQSKSQMAMWAIFAAPLLMSVDLRTIRPEYKAILQNQAVIAVNQDPLGIQGKRIYKDKGIEIWARPISPISQGHYSYAIAFLNRRTDGTPSEVSVTLRELGLAFPGGYAITDLFDGVQYGTVLPDKRFKVDVNPSGVVLVRCEVVKTTGFGSDVRAPVNPAQPQSAFRNPFNNQLFNPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMP0</accession>
    <name>A0A423SMP0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_016538</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMP0"/>
    <dbReference type="STRING" id="6689.A0A423SMP0"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000364">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="86"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="266"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT65507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="50314" checksum="823754EF77017D36" modified="2019-05-08" version="1">MADMATLPNHASPVKPIINNQVVKATDDRSWKAQIQVPPKDRRKRTSDVTDTKGNEFEDFCLKRDLLMGIFEKGWERPSPIQEASIPVALSGRDILARAKNGTGKTGAYSIPLLEQIDPTQNHIQAMVIVPTRELALQTSHICNELAKHIGVKVMVTTGGTNLKDDIMRIYEVVHAVIATPGRILDLMEKKVAVMDKCKMLVLDEADKLLSQDFKGMLDRVISYLPAERQILLYSATFPLTVEQFMKKHLRSPYEINLMDELTLKGVTQYYAFVQERQKVHCLNTLFSKLQINQSIIFCNSTQRVELLAKKITDLGYSCYYIHAKMAQAHRNRVFHDFRAGLCRNLVCSDLFTRGIDIQAVNVVINFDFPKMAETYLHRIGRSGRFGHLGIAINLITYDDRFALHRIEQELGTEIKPIPKVIDPALYVAEHHLEEDDEGNISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPU9</accession>
    <name>A0A423SPU9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA exonuclease 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_015807</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002982">
        <property type="protein sequence ID" value="ROT66189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPU9"/>
    <dbReference type="STRING" id="6689.A0A423SPU9"/>
    <dbReference type="OrthoDB" id="8191639at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06144">
        <property type="entry name" value="REX4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000007">
        <property type="entry name" value="Interferon-stimulated exonuclease gene 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037431">
        <property type="entry name" value="REX4_DEDDh_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF158">
        <property type="entry name" value="RNA EXONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="9">
        <location>
            <begin position="163"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="336"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT66189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="353" mass="39598" checksum="75489529137EE5D4" modified="2019-05-08" version="1">MRANGSIPVTNTTTKRTLEDDHEASGPLKRKKEDGIQNGSTADSSASNPKEPVKTGKQFSSNWMQLKMILEKQHKASNPHGISREKKDHNRKKMAAGDGKRKEPVPKEKPDIWFDNVDPLLLESENENNNSIDGGRSKHKDDGTLENGDAAAPVKKTNEELTQVIAMDCEMVGVGMDGKESILARVSIVNHSGKVLYDKYVKPLEKVTDYRTQISGIRHCDLEKGEDFKTVQKEVADLLKGKVLVGHALKNDLKVLFLSHPRTRIRDTSKYKGFRRLFKGSTPSLKNLTEKLIGVKIQHGEHSSVQDAQAAMRLYTAFRREWENSKKQFNKKKTAAVKDKSKDKELEVDADAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPX5</accession>
    <name>A0A423SPX5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002972">
        <property type="protein sequence ID" value="ROT66228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPX5"/>
    <dbReference type="STRING" id="6689.A0A423SPX5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032222">
        <property type="term" value="P:regulation of synaptic transmission, cholinergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030431">
        <property type="term" value="P:sleep"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23591">
        <property type="entry name" value="TFP_LU_ECD_Crim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031424">
        <property type="entry name" value="QVR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17064">
        <property type="entry name" value="QVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="140" mass="16405" checksum="FE34C44FF8B5D7AC" modified="2019-05-08" version="1">MLCRQISYFTLCTKDLLWPSDSPWVDWDFRKGTGEGMCKHSWCYRCVGSHPGCGLYDFDWRYYWSYQCPDPYDKCVKVIEQKGAEELMVTRDCLSNLEGHRRDIPADRYEGCRTAAADPLLGHYIFPSIKEIDHKRFGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQQ2</accession>
    <name>A0A423SQQ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002918">
        <property type="protein sequence ID" value="ROT66547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQQ2"/>
    <dbReference type="STRING" id="6689.A0A423SQQ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="42815" checksum="35CF37A83FCC479E" modified="2019-05-08" version="1">MPFPAPPPLLPFLFGLPPPPSFPDLLPSLSDHSSFSFAHHHHTTITTTRTIYQSPQPLTTTATTITTNYAHYHNHSTSPNHTSTTAAINHHPHSPSTHKHTYNHTTSTPHTVHHHLTTTNHTNTPPLLPQPSNNHHSTPQPHPPPPHTPTTTLPPRTTPPNPHPPRIPTSSTHAPQSPPPPTTTSPHPNSLFHAPTNSPRNLSLLPPPKPPPRSHPHLLPTPASLPPHHLPASIHPPHQQPTYPFPPTQPPPTLLPTSSRPSHTTPSLPPHHSHHPSLSPRPTQPLSPTTPPHTPPHTPASLLPHHHHSPTQHHLHHPHPHHHSPPHTLPHTPARLSIHPASSLHHHHSPHQPPAPPPSNPSSLPPHHHPHNPSSSSHHSPPSASWGCRRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STB1</accession>
    <name>A0A423STB1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002810">
        <property type="protein sequence ID" value="ROT67429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STB1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="563" mass="62979" checksum="CFD36108C1B5718C" modified="2019-05-08" version="1" fragment="single">MLSGPTALPPFILFMAVLTPFLLIPRITRSSISTSSNRLFLMLSIFISSLKYSFHLLNSFSSLAKIFPSASFISLTCCTSRTARSLSLADCFPNFFFSRFSRFCPSLSIPFISPLLFLLPHHSPSSPLSSFFLLLFFPFLNLSLPSLPPLRLPYYLHFLVIYRRLPFHFHFPFIYFFYSYFFLLSLFHLSLFIFLTLPLSPFRKFSFPSFSISFSFSLSTFSSFFSILPSLSFIFFSLLPPPPCLPPPTLLQILLLLPPYPIFLLFLICLPVSLLLALFSLPYSCLPSSSPSLFSSFPPVLSTFSPLSFSRLPFLLFPSTFSLFHSSSFLPSPHPSSYLILPIPSIFSPPLPYLLLLPSFLLLSLSLPFPFTHSPPIPSTFSPPSPSPVSFPTFSFSPNSFFFSPLLFPNFLIFPNSSSLLPSLSFPSFSFPLNSFFLLSPSLSDFVILLQFLPPSPLLPSPLPLFPNYKNKWNRRATRSETPPESDLRRRGPLTPVNGRARRRRPRNAGVSRNPIFPGGIRAARRGASGVKRRRVPAPPPLFPDGEARSGVTRPAGGGGGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STZ8</accession>
    <name>A0A423STZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002780">
        <property type="protein sequence ID" value="ROT67677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STZ8"/>
    <dbReference type="STRING" id="6689.A0A423STZ8"/>
    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009836">
        <property type="entry name" value="GRDP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365">
        <property type="entry name" value="ENOLASE (DUF1399)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34365:SF7">
        <property type="entry name" value="GLYCINE-RICH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07173">
        <property type="entry name" value="GRDP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="47467" checksum="EBC3224DFD78401A" modified="2019-05-08" version="1">MRVVAGVPVVSAAWVVAPVEVHALKKAHKRTRKLWMEMYPDEPFDVILDGSQPVLLSQYTSLISYDLEAAVARQSMFYYQVSLPHCLMKSYLKEAVERYKKFIYLKFSNPAKFLVPCYDMDIIWHAHMVHPKKYAKDTQRILGKILNHDDSVNDRQPGSKLTTSDSATRRLWANTFGENFARNGGHVIEPVPAELKKAALGSAFQLHVAIGGAPPGTLKIKLVHQLRIFICLSVCLLPSFPFFFEILLLPFFLLLFLFSSYTYSSFSLISLSSSPPSFLTPYPSFHPSSSFFISSFSYSLFSFPPPSPPFLPTLFPPFSPLSPFPPPSSFLPPTLSSLPPPFFLPSPPLPPSPPPPSLSLPPPPFPPFPPLPPSSPASFLRSVILLSIRPDPFSLLMLFYSSNIFSLLLSSFQRRNKEMELRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUK9</accession>
    <name>A0A423SUK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002743">
        <property type="protein sequence ID" value="ROT67879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUK9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="529" mass="57204" checksum="424F2C18D17BF1BC" modified="2019-05-08" version="1">MSVRVPTLTFVLLLPFSLLVIPCFSFYFSSFIFTSNPISLTLVTLSRAPHPSSTLLVSLAPSNLYSFLSSASFPPFLLPLFYFFLLLTVLSLHPLNVFPPLSLLFQLLFLFFLCLVPLSTFISPLTPFLSLSSSHIPYSAFPPFPLPSLPPFPSSSLSSFSTVSITLLLTFLPPLPPLSSLSSSFPFLSNLFPRLQQLLPLPFLKFCPHLPFNLFFSSLTFPLFPLSPRYLLSRLLSLPLFLISYSPSFSLHLSLFSPSSLSLFFQQAFLPSSLPLMLPILLLSISPPLSQSFYNLFPRLRTSFHSPLAFPLPSSPSPPSPSLPLYSLPSLSLPSLLTHLLPPLLTPHLLSLPSLPLCSCPPSCPLSFLPLSPSSSLLLLNLAPPPYSPSLSPSFPSSIAPPPLLPSPPHFPPLLLPSALPCLSKPPPSSLAPPPSPLSSLPPSLPLCSILPLPLASLSSPSHSLLLLNSSPQFGETVSAINPRLMPAGSNRGYSVKIGFPIRSPASCHNVSSYRLPASGCPAFTIWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXJ1</accession>
    <name>A0A423SXJ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ORF27, putative DNA polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002617">
        <property type="protein sequence ID" value="ROT68955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXJ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="596" mass="68178" checksum="2A427D7878277789" modified="2019-05-08" version="1">MNVSVVSAMYLTQLHIIEGAVLRAMGPERAFMRSCAIRCHSQYTKTLGGYVTTPLTKFQTLHAMDMGSLYPSAMRQNNLDTTTVCSHRQIIDCRNRIMMQIMAKKKPSSSSFSSSFLWGTPEALAIMDEANAFIMDRYRPCDLVVDSWKNNRKLKPNCCVTRQNCKTVIEQQQQRNHDSGDAEVTARLTNSLEDVVNMLEEDFTLEKDQILVKTRYSYSGNVCRQEKSRGISVLAQRQAHRLMSICVRIARRVYAYDSAKDEAVAKWSSRLLNVGNRCRVWNARQWILQGTIPLLQRRYREERVVLKRQVKLKAKSEPLAAAQFKVEEGVKKLFMNSIYGVLVLRVSSQQSDSISRWKTDNSLSRLLVGHAAEGVEGGRDTLPWNEENADYVYPHNGPELCRLLTDDERAILLNRQSGGAIFSDGPLLPIDRHDNDEVKENKLREIQTACLAWTQHQLFNYDTVVGGHAKRCLSYTEDPEDYITVSRVNKEQVPKKIGDIVTLPNPTARLINNHLNPSRVIELGEKILDRLGDEWSNANSWTRCHGKGPAAPSQEKMESNNRERRPGRFLGKKSRCRLSHHALYHGTREERLRFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXS9</accession>
    <name>A0A423SXS9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5 7">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012783</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5 7"/>
    <dbReference type="EMBL" id="QCYY01002610">
        <property type="protein sequence ID" value="ROT69054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXS9"/>
    <dbReference type="STRING" id="6689.A0A423SXS9"/>
    <dbReference type="OrthoDB" id="2015992at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10420:FF:000007">
        <property type="entry name" value="5-formyltetrahydrofolate cyclo-ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="7"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="142"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="22484" checksum="FE4F2C997A561953" modified="2019-05-08" version="1">MPLKTAKSLLRQELKAKLNAMSPDERTRQSQIVQTKVLQHDLYKESKRLSIFLSMHDEINTDLILHDALSFGKAVYIPRYDSKSTYMDMVRLRSWEEYDALPMTKWKIKQPPLDQDREKALDSGGLDLILVPGLAFSKAGHRMGRGRGYYDTYLARSRVMQEHPPNTIALAFVEQVLPQIPVEETDVPIDIILSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZ96</accession>
    <name>A0A423SZ96_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012276</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002557">
        <property type="protein sequence ID" value="ROT69509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZ96"/>
    <dbReference type="STRING" id="6689.A0A423SZ96"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="269"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="45908" checksum="2147A0EEB381A773" modified="2019-05-08" version="1">MFGDENTLEWKSSTLDIRRRHFGSHGSPRRRRRGRTSGRAEEPPKCDGMMLCGAEISAGSTDRGGKRDEARERRAASRPPIPRIRPRLPSQERNAGSLFPLFASVPPSPSPPAAAQGLRSPRRPAWSVDGACEGRGERGFLCVLGKISPGEKVAILDDWGRGGGYGGSGGGGRPSLKGRQPGERLRKPKWDLSRLAPFEKNFYQPTPVVVNRQPYEVEQYRNEKEITLRGKNIPNPIQYFTDYNFPDYVMAEIRRQGYEAPTPIQAQGWPISLQGRDFVGIAQTGSGKTLGYILPAIVHINHQPYLERGDGPIALILAPTRELAQQILTVAQDFGSSSKIRSTCVFGGAPKGPQIRDLERGVEICIATPGRLIDFLEAGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVEQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZH9</accession>
    <name>A0A423SZH9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fibrinogen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002537">
        <property type="protein sequence ID" value="ROT69670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZH9"/>
    <dbReference type="STRING" id="6689.A0A423SZH9"/>
    <dbReference type="OrthoDB" id="6145874at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="149" mass="17200" checksum="13B64F03D12CEBFB" modified="2019-05-08" version="1">MTKGKNHELRVNITDWSDSETWAEWKEFSVAGEDKYYRLKVSRYTSSSQAGDALKWHNGMRFSTPDRDNDALLGGHCAKKNSGGWWYRGHRGCYQAHPTGRYQHSPGNPPPPTANSRNFDMGPVLVWQNWRGESYYPKSLFLMFRPAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0U4</accession>
    <name>A0A423T0U4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative cAMP-dependent protein kinase type I regulatory subunit isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_011739</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002485">
        <property type="protein sequence ID" value="ROT69993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0U4"/>
    <dbReference type="STRING" id="6689.A0A423T0U4"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007611">
        <property type="term" value="P:learning or memory"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0114">cAMP</keyword>
    <keyword evidence="3" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="73"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="199" mass="22102" checksum="27D50B683A9D1956" modified="2019-05-08" version="1">MIFVNGEHVTSISNGGSFGELALIYGTPRQATVKAKTDTKLWGIDRDSYRRILMGSTIRKRKMYEEFLSKVSILDSLDKWERLVVADALEPVSIESGATVVRQGEPGDDFYIIVEGTAVVMQARSPNEEPVEVGRLGTSDYFGEIALLLDRPRAATVIADGPLKCVKLDRNRFERVLGSCGDILKRNIEQYNSFIALTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2C8</accession>
    <name>A0A423T2C8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002398">
        <property type="protein sequence ID" value="ROT70689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2C8"/>
    <dbReference type="STRING" id="6689.A0A423T2C8"/>
    <dbReference type="OrthoDB" id="10255963at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF8">
        <property type="entry name" value="UPF0047 PROTEIN C4A8.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="169" mass="18841" checksum="15433302EB8B6D10" modified="2019-05-08" version="1">MASSSRGIQIGSAWFQRKIKLRPQHRGIHLVTDEILKEIPELRQFSVGLLHVQILHTSASLALNENWDPYVRDDMEMMLNKIVPEGMPYRHSCEGPDDMPAHVKACFIGSSLTLPVSEGKLNLGTWQGIWLCEHRNDAGPRKIVVTINGCLRDGRTPVSPMSPMASTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2P9</accession>
    <name>A0A423T2P9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002399">
        <property type="protein sequence ID" value="ROT70675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2P9"/>
    <dbReference type="OrthoDB" id="10630836at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="285" mass="30787" checksum="DD0E1940C2A53570" modified="2019-05-08" version="1">MKVATSMGVMSSPSSTSHARKLAAREGGEREKEAWASSMRDLATPSRRSCRPEGLAKGAPPVRPLVHGRLLRPRGDAAAARGVPCHAPLTPTPSSSHFYSPIASEDSYPRPVHDEPPLKARRSEPRPNPYNDSRPPIPAAHSNLSNVHPAQPTAHFPPTAHPTAHAAHQMPYAPKESVGVGVGGLSPRKALIQDVVLKESTRAFRSHPLFPLPEGPLRRSTTTSIGCLQYRPLLSYLPTSTEDLVSRTWNPDVAQSYCGHQTSSLTVLPSTPCSWMPSRTPILVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5C3</accession>
    <name>A0A423T5C3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative tetratricopeptide repeat domain 11 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009947</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002259">
        <property type="protein sequence ID" value="ROT71704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5C3"/>
    <dbReference type="STRING" id="6689.A0A423T5C3"/>
    <dbReference type="OrthoDB" id="421154at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043653">
        <property type="term" value="P:mitochondrial fragmentation involved in apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028058">
        <property type="entry name" value="Fis1_TPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14852">
        <property type="entry name" value="Fis1_TPR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="137" mass="15224" checksum="7BA69BA4317EEF62" modified="2019-05-08" version="1">MEDVLSEVCSSEDLKVFEKKYNDELVKGLVSSTTQFEYACFLVRSRYPADIQRGVVLLEELYKRPEEIGKRDYVFYLAIGNARLKEYQTALNYLKGLLRVEPGNRQVQELETGAAIAGGAILGVGALIGLGMALAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB50</accession>
    <name>A0A423TB50_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox protein slou</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007926</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002013">
        <property type="protein sequence ID" value="ROT73632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB50"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF37">
        <property type="entry name" value="HOMEOBOX PROTEIN SLOU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="29"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT73632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="164" mass="18332" checksum="CE515109ED910BB0" modified="2019-05-08" version="1" fragment="single">MIRRPSRSPPKERPLRPRLLPPSGASCRSRRARTAFTYEQLVALENKFKHTRYLSVCERLNLALALNLTETQVKIWFQNRRTKWKKQNPGCDVSTPPLSTGGSTGVTCFPMEHQLYPQLAYLMAPGMALPRAPTPEPPAPLAPPAPHVKAVQVELTHSACNQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB59</accession>
    <name>A0A423TB59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methyltransferase-like protein 7A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002011">
        <property type="protein sequence ID" value="ROT73651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB59"/>
    <dbReference type="STRING" id="6689.A0A423TB59"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="83"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="29250" checksum="8C2A86B1107D637F" modified="2019-05-08" version="1">MLYSILAWLSNNFITVLAVLVVLWIVQKIVFATQDRWFAYVMHFCTKDEFPKLEEVKKDHFASLKDHVSHDPELRKKKVIKILEIGVGTGVNFAHYPDGCRLVVVDPNPHFKEYYDNNRKKFPNIHSEDVLVAKGDDMHMIADGSVDAVVITLVLCSVDNIDKILRWQVLYFMEHVQEFDLKKYSLRKNLQDFFTWCGLWPFIFDGCCLNRDPMPAIEGAGFSKVEVDHYYAPVPNFLFWVEMPNVKGVATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBL0</accession>
    <name>A0A423TBL0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001978">
        <property type="protein sequence ID" value="ROT73854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBL0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="499" mass="55194" checksum="C79A4F09568A3BBC" modified="2019-05-08" version="1">MNSLGHTSLLHAHESVTLSNVSPSRPRICQATRPHTSSRHEPTKPRPASPSRHEPARPHAHSISFTPTKPTSANTPIRFFTPTELAIPHTFFFLHAHESAKPHPFPLFSSTPLVPFPSSSFSPNFTFGLLSPLHSNFILCLISLFSLTSPLLHPCLLPSLPLFPLLLRLLSPLNPIFTQALSPLSLTSPLGSFPLFISNFIFVSFPYSPHFTLELHPFASCSSFFLFFTSFCFSFSSLLPLFSPFLLYPFFHPFPLPPFLLFLTLFFLSSPFNPFFFPFPLPFSLLAPFFSLLPRSFFLSSSPLPPFLFSAILPSLPLHFLLFPSSSFFLLTLLPSLPLFLLSSFLLPPSSSFLSSPFLLPPFSSFFIPPSSFSPLPPLPPFLLFLSFPSSIPSPLHFLLFLSFPLLPFPSSFSSSSPFPPSSSLFSSSSPSPLPPFPLLLYFSLPPLPSSSFFPSSSFFSFCPHPSFPSPQLPPLSSSALHLLLLTSSHYILLSLGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDV5</accession>
    <name>A0A423TDV5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized oxidoreductase dhs-27-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001866">
        <property type="protein sequence ID" value="ROT74653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDV5"/>
    <dbReference type="OrthoDB" id="6334212at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="138"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="43156" checksum="D70AFDB2E54A80F8" modified="2019-05-08" version="1">MAASAPELRPLHAEQDISEKWLQAMLTLKFGCPVRVHAWTSRTPRGREGFLSEIAFVSLTYSKDGEEGTVDASLVFKFLPQDPALRQFLANGGLTKREVEFYNFVGSSSFQEICKQCGIVLPVPETYYAGYTEEAITIVLHDMNTDKFKSVIVKEGSTLEQTRVALKAVALVHAAGLLFINRHGKSNSLKTLASEFRTDFYDQFFLPNLDTLSDMYKGSPLSSTMLALKPLTQKMYKVSEKRPFVETVIHGDLWAGQLMYSDDESRAVIIDWQFCRASNPVTDIVSMFFMSTDPGVLPNYEELLKDYWAVFTDTLKAGGVSTELTFENLLASVEDCWILGFQFLAVSIHDFMGGGSITDERIFGAIDFLEKRGVFKKFIKEFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF07</accession>
    <name>A0A423TF07_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative protogenin-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006463</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001819">
        <property type="protein sequence ID" value="ROT75016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF07"/>
    <dbReference type="STRING" id="6689.A0A423TF07"/>
    <dbReference type="OrthoDB" id="6373243at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050991">
        <property type="entry name" value="ECM_Regulatory_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708:SF2">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46708">
        <property type="entry name" value="TENASCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019007950" evidence="4">
        <location>
            <begin position="26"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="682"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="316"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="599"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="798"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="854" mass="93282" checksum="E1A4C464B570CFF1" modified="2019-05-08" version="1">MTYHLILLLPPIPAILILLPPPISSSPFPNPIPHPFPPPLLLPFLYLSSPRLTIHTVPPLSLRSPSHASPFIQPSTTPSLFLSSDFLSLPPFPFSLLAPSPATAGREQSVTTPRANEISSAPYTSTSISCAPSSSTRRAEHLSEEPSQLVVAPWQPASTNTTSYEILKLTPYTLYSIYVRHLRHSTREQQNHLIGEPSATLVVRTMASRESGVVLAVAWRVRLGRWRVWLGALQHPDIKLDPLSPTKLRVTWAPLSLEEARGAVVKQKIQWRRWRMHFFENAELSEDDRYEVRVLVATESGYPEHESNLPWKHIRMPSDAALSTAPVVHLSVDWVLPDQLRTKVLWFVLTYNSTAQNKVTRDLEASSTSYVLHQLEPRTNYTVKLEPMYKIGRAGSGVSRTIRTLPIDAHPTPAHGHLRKMGVKNLKVKTLNSTCIQMSWRPAGRRVTPDFYTRVRGHGHGVGGGRDQQADPAHQNQHQGASSPLVRPFPSPSLSHSSHSLPSPSPSFPLFSPSPSFPFFPLSLSFPPFPSPFFPSFPLFSPFFPPLSLFPLLPSLPLSSPLLSYLPLSSPLFSPSFPLLSPFFPFFSLPLPPPAVPSAPTNVSWTPVSPKDVALRWSPPKDINGVLLNYLVSYSHDQQEWRNHTVSHEATSTEIRGLISNTNYTEHLGGDPGGRREADQGVLTVIVVAVLVAVTCSVVLVVCVRTARLRRTGGHPTLQGGPGLHDDGIVASCPHDVHTSQITLGRMAAPLPNTAAAASAGLFPGRDGASKDVEDTLDDIDDDDATSTLLQGVAAAPDPKRDLVDPKRSLVDPTRDPADPRREPADPKAPSEAPAGAPPPRSTDGARAAEVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG45</accession>
    <name>A0A423TG45_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative translation machinery-associated protein 16-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001784">
        <property type="protein sequence ID" value="ROT75335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG45"/>
    <dbReference type="STRING" id="6689.A0A423TG45"/>
    <dbReference type="OrthoDB" id="270284at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021346">
        <property type="entry name" value="Tma16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349:SF2">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11176">
        <property type="entry name" value="Tma16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="79" mass="9275" checksum="477C8F322D53C697" modified="2019-05-08" version="1">MGKHKINVLKENQKVIHPNSRKAKKLSKMVSREIKMKKRRGENNLKLQVLGDKLLWFKKEMDPSIEVVTPKDVLNLIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGC3</accession>
    <name>A0A423TGC3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001762">
        <property type="protein sequence ID" value="ROT75508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGC3"/>
    <dbReference type="OrthoDB" id="6356954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005549">
        <property type="term" value="F:odorant binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036728">
        <property type="entry name" value="PBP_GOBP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47565">
        <property type="entry name" value="Insect pheromone/odorant-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019316352" evidence="1">
        <location>
            <begin position="21"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="181" mass="20436" checksum="E22D5F02FA811394" modified="2019-05-08" version="1">MKYSLALFLVAALCLLPGLCLEVWKTTNDYISFAVMKSCLGEELTVQMERKGILLGQECLQKLEPQPASLNARSRRNILKMPPNPSVGLQMCNMKAWDMLSEDGTILFENVDSFFRNVSHDKTLQDDFLQLSLSCKTSSPPTTGLQEDQKHTVVVSYLSCLNKGGLKACMDYEHRKYFNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGZ8</accession>
    <name>A0A423TGZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SRY-related HMG box C protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005651</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGZ8"/>
    <dbReference type="STRING" id="6689.A0A423TGZ8"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007420">
        <property type="term" value="P:brain development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000002">
        <property type="entry name" value="transcription factor Sox-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF323">
        <property type="entry name" value="TRANSCRIPTION FACTOR SOX-14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="48"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="48"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="124" mass="15173" checksum="47DAA93D8F9D18E4" modified="2019-05-08" version="1">MRRREEKEEGRGGGGGGVEEKEKKKEREKEEEEEEEKEETKKHPVNHIKRPMNAFMVWSQLERRKIVQRHPDMHNAEISKRLGKRWKTLSSEERQPYIEEAERLRLLHLQEYPDYKTLFKVWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN94</accession>
    <name>A0A423TN94_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003372</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001456">
        <property type="protein sequence ID" value="ROT77931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN94"/>
    <dbReference type="OrthoDB" id="6349274at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="370"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1159"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1183" mass="133656" checksum="D48FC50E08154FF4" modified="2019-05-08" version="1">MIKFSHRGSSISRSTDVSELPDTDRSPGLRLEKNREVQTNGGATRLMQGDRSAFDGSKIEGCTEARTQSKDPIEMTTRARTTTLTRHTVNGFRYQVAVIAKGRAVLVQAVEWLYQGGPCVKSYFLSLGHSKADYKRKFNSEQRHLLERGVPFKEYDISLLYIVLQLMCGLAGPSDPAWASPPTGQPLEHLLHKVKMKRNDIAHSNDVRQMSDQELIKELRKLRCLFSGILRLAGNRCGIRPHVFRDQVWEIKQNFQDLLEKVREPLQASDLDKFPQLQQEIQVFQKALQNKIKEASERELCGLYPQLWDVTLAQWLYPDLKIRPSVNFTNLVIKEDTSTLSPSQEQQHQPRDISHKDLLQITDVYDRLPEVIIIAGEGGIGKTTLLKHMLEMWVRDPSQIKGLQNVSPLLYLQLRGSTLTSWKGMLESALCGTFQESGLTIDIFADLFQAMHVVVLLDGYDEVSQQAKELITDLISYRRNMRIVITTRPSCQKELTQIMKNKKQVMNIEIKGIDRKDRHFFIENTLAALVQDPVRRDELKGKIIRNLENLKTGKGDLDVPLTLTLLIIRDVEAPDESSPDVYQDLTSLMMKKVKERLAAKGIGVTLEKVREYHEFQRGVALRCLKKREHDLLSETVEDLKAKCNELNLPYKEILSGFLISKKFRQGLFIVHVWSFPHNRFQEHWASSHIATQLSKMSRSLPDMSGLLDFAFLTDVEKKKKLGMPGLPTEEEVVTFMFTKNPILQVYVDNIEEAKELVWGNIGGDISALLMEIVFNIARIFSSSRENLLDKFASAIISFILYSDHSHLISKNSCHRICETVMASGHHASILEAAAKVLRTSGTLMTRGEYLPGFVALFDYVRPSCVEVFMSKDTEEFPPSWQVSGLEALSKQNIELILTINDIKSSIQFSEACLRAVTGPGSFCRLTKFGGELTEVGMQLLPESLEELNTKSDAEGVRALVPRLQHLQRLQTLGPADSRRGEPSARALRKLSVETDAEGFRALAARLPRLEKLQELEFEGHLTEAEMPLLPEVLFSLRVRTDAAGLRALARRLPRLTKLTSLNVRLLDCPPADSLSALPCEAPFLTLDLRHVTPPSWEWVCDAVQQVFLGRNSEYSVHLPSEYDELQTQRIGQELRGRGATLSCWLQVLRVFSFPLAVRPRPASDASGGKESGREGSDCVRSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRL7</accession>
    <name>A0A423TRL7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001290">
        <property type="protein sequence ID" value="ROT79099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRL7"/>
    <dbReference type="STRING" id="6689.A0A423TRL7"/>
    <dbReference type="OrthoDB" id="425619at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="34"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="50528" checksum="1091987749C95EEE" modified="2019-05-08" version="1">MSSEVARFCRSCDPCQRTVDKGRVSRAKLGRMPMITEPFQRVAVDIVGPIEPRADDGSRYILTIVDYATRYPEAIPLKNVETVSVAEALMSVFSRVGIPKEIMSDKGSQFRSDASTKFSPFELIYGHTVRGPLSLLKDLWEASERNITDETRTAYEYVINLRERLAETCKVAQEELQKAVDKKFHINMLKRYYERGECETERTADDVMVDGDEGVTVASVAVIHNEESDADVDVVPNYVQTEDVNDVHKGIEEEIERMLRLGLVEYSMSPYSTPMIAVKKKDGSNHAGLTARPCKTEIGKSSIEYLGHCVGSGTSSTTGDKIKRVLNMAVPRTKKEVRSFLGLTGYYRQYIADYATIASPLTDLTRKSVPNKVSWEICHQDAFDRLRNALAIFRRDVTATTPSHLTSSPIAMQGSSSIRRWKLFWKDISCRGRPFHLELRHTCRVEVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSZ5</accession>
    <name>A0A423TSZ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001223">
        <property type="protein sequence ID" value="ROT79578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSZ5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="49290" checksum="1AB22BC8E5CAAD2B" modified="2019-05-08" version="1">MNSTPHFLHINSPLSPHPPHPSQTLSPTTTQPTTPSLYHHLSPIHPDPAPPPPSPPPPPITPPTLPHKPPTTPHKSSPHHPPSTHHLPHHTPTNPPASHPPSCTPTASLLPTTCTSYTTTPSPTLTSGPHLLDEPFPSTHKHTLHFQIPRSPTSALSRPLSATHPTSVLNPTLTAPTKRTHIVEPNCLYLRHALHPNSLCCKFYCATISVPSHNSPHNYLQAPRHHSATPVPSASISARLSFIPIQRVPLYKYTDPHLYSDHTPNRASTLPISILPSGAANNSPDRTPLSHTHLSLSTVAAASLSTHTREHNALRPRSSLTSEERPPQAVPNTIFLLCLRQCVPIVTHNSRLAGAFSTTDHLSGYRTPHYIHPPSVKSKQFLRAAPPAHRKLCSHPSARCLARRRASDTPPSTELSLPYTAPLQSRPVPIYLHPVLTALASDTKLHTTLTNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT63</accession>
    <name>A0A423TT63_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TBCC domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_001628</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle pole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001210">
        <property type="protein sequence ID" value="ROT79648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT63"/>
    <dbReference type="STRING" id="6689.A0A423TT63"/>
    <dbReference type="OrthoDB" id="427777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051684">
        <property type="term" value="P:maintenance of Golgi location"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039589">
        <property type="entry name" value="TBCC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052:SF0">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="7">
        <location>
            <begin position="206"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT79648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="470" mass="52634" checksum="4A9F4208E4218DD4" modified="2019-05-08" version="1">MELSNLCLYLHRCYTSAHPRAVARQASLQSLTTDPYPCHRWPNNNSTGTSRKQLLEEKHSEFVREALPELLSLLAGHLQVEDTEKKKKTGDKRTARELLGFMKSAGVLSVDVVKSLSFILGASVQGEKTERDLLSVATDANNCYRSGYLSKKNAFQKGLFEQWLLRGLDWAPHGEWLCVRRGCRQSWPVVSLTQPSHHRLVASPAPGYRLMYICELVDGMTAYMGEEATYTDLKVRRCSKSNIFVLQPLRHAVIHKCHDTRVVLGPVAGRIKLSECRNTVVVCAARSLVIADCRGIVIHTLTPQRPLLVGGRTQGVTVAPLNIHYPRLKHHMAQTQLRPHINMWNRPLHLGSEGGVLSGACEVMNPEDFQLLVIPFTQTAPVDGRPPLLPPGLPHEFAKSVEEAGKCVSSFRAEVRDADLTPEQRAILQKAIDARFKAWLRDTGKQRELDQLEKLALTLKYERVAKTTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU76</accession>
    <name>A0A423TU76_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative hemicentin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001167">
        <property type="protein sequence ID" value="ROT80013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU76"/>
    <dbReference type="STRING" id="6689.A0A423TU76"/>
    <dbReference type="OrthoDB" id="6378907at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056475">
        <property type="entry name" value="GBD_Hemicentin/VWA7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056861">
        <property type="entry name" value="HMCN1-like_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052577">
        <property type="entry name" value="VWA7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905">
        <property type="entry name" value="NG37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14905:SF7">
        <property type="entry name" value="VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23560">
        <property type="entry name" value="GBD_Hemicentin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25106">
        <property type="entry name" value="VWA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="338"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="428"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="535"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="626"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT80013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="660" mass="72341" checksum="FC8681AE8DD9E360" modified="2019-05-08" version="1">MTVTTNPEEFLMSLQDLTPTISGGGDCPEMAVRAIKMALETSVPSSYIYVFTDARAKDYHLLDDVLKLIQKKQSQVVFVMTGDCGNHTHAGYKAFQSIASTSSGQIFHLDKSNVNKVLTFVELSLESRKVNLLSLDRETLDPRGDLPLLVDQTLKQFTISVAGKKPKIEIFGPRGEDVTRKEGVEELLTLENVKVLGVKEPEPGRYNISVGSESEYTVRATGLSSLNFEHGFSLKPTTNFKETYHRPVKGGISYVVVRPHDVTEFGDIYRLQLVSLDGEVLEDMPLTRLPGSGPVFNGTAFPAPDVPFNIKIFGRDQDGYQFERISPTATTAQLPFPPEVTSASRVYGYFGRPAVIICHVHTLVPFQLSWQRDGIDLGPSVTHPQSAEVEYVVESPQRDDEGRYTCIATNSAGSTSSTVFLDMKEPPPQITTAEEVSLPPSRPALLTCDVYSTVEHNVTWSRYIIKGQVQDYFGKTETIGEFVNVKNVRGYRMLSNTSLLLENVTSNDEGWFRCSAANEGGRSSREIHVSVQSPPQVTVVPEVAPFSAGDNVTVSCVARGFPEPQVSWRRYDVQIGRSYTRVREDEDHALHVASAVHDDEGPYVCMASSSAGSAEATVTLAFMERAKDPAGARQGPGSQRGHGLAPVLRRGDADSPPSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXX0</accession>
    <name>A0A423TXX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Neuropeptide-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000990">
        <property type="protein sequence ID" value="ROT81314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXX0"/>
    <dbReference type="OrthoDB" id="6426745at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="309" mass="34288" checksum="6FE48741C5536A65" modified="2019-05-08" version="1">MKLIRYKTNKKAPHSRSTFLSFQGAEIQTTSTTDERLTGDAAGSDAGDDATAYVSGPRERRFLGPQARRSWFVDNAGPRTWGFSVGTLPLDSNYMSKLLQRANLRSKYRKNAALRSVEKKSMSSLAAANNMPRSLKSSLTAFAPDDRLKNHDKRSIASIARDGKFPSNVDMKRSVQDAASAEDEKRSLSSLARSGNFPFPLDEKRNVAYIAKTKSNAMDDVAEKRNVAYIARTNSMNLGNAAEKKNVAYIARTNSMNHDNADEKRNIAYIARTNMIMPTTLLTSPEPTVKTWKIRARKGTWPTSPEPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZX9</accession>
    <name>A0A423TZX9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ITPR-interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000897">
        <property type="protein sequence ID" value="ROT82001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZX9"/>
    <dbReference type="OrthoDB" id="6360485at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029325">
        <property type="entry name" value="ITPR-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043444">
        <property type="entry name" value="TESPA1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17469:SF15">
        <property type="entry name" value="ITPR-INTERACTING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17469">
        <property type="entry name" value="SPERM SPECIFIC ANTIGEN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14722">
        <property type="entry name" value="KRAP_IP3R_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01257">
        <property type="entry name" value="KRAP_IP3R_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ITPR-interacting" evidence="2">
        <location>
            <begin position="34"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="22334" checksum="08C2A43C843AB167" modified="2019-05-08" version="1" fragment="single">PLTLSDVASSMQRQQEQEQAEALGVEGRRSQFAGLREKQASFQSELSGLSLQSKSSIDSLLESREADPVDVLLSLGFGGQAQDTVTRIPERFLRPSQVPGNNIEDFLKSEEEFSDMMESAEWMPGLDPHGVTMAGALSLSPRGRCRLRRRQYYHRPSSPQPSVRSLPASLHHPSRSPRFLTVLWEGHARAFPRSVVDDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2X4</accession>
    <name>A0A423U2X4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_023774</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01000746">
        <property type="protein sequence ID" value="ROT83046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2X4"/>
    <dbReference type="STRING" id="6689.A0A423U2X4"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2130:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000726">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="348"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="537"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="288"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="966"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="975"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT83046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="985" mass="113550" checksum="3B37DAD7216671BE" modified="2019-05-08" version="1">MGDAVKRWVSMRLHDVLGMSDPALAEYLIRLTERMPSMTHVLAELEDEITIDRAVEKFIGELWDRLIKKRRGGSSSSDDGNDEERQRRRDLRERDEYAERLRKRDEERTRNVANKGEEKAFEEAAKRLLLEKEGREKILPHLRVESRRKYLVKRKDDKLRELEADIQDDEYLFDDQVLTERERKEREYKKTVLKLAKDYDRVKDAEKVQRYVMPEEGGTVDDKYVEIDDKEKKPGYEQKKWEEDQMRGTALSFGARDKAEKYHSHEYNLVLEDEIEFIKSLPLEGTREKKKKKKKKKRREEESESSSSSEEEEEEEEAPKMSEHEKKKMTIAEVRRSLPVYPFKEALLDAIAEHQVLIIEGETGSGKSTQLPQYLYHAGYCSDGKKIGCTQPRRVAAMSVAARVSEEMGKKLGNEVGYSIRFEDCTSDRTRIKYMTDGMLLREFLMDPSLEGYSVMIIDEAHERTLHTDILFGLLKDITRFRSDLKLLISSATLDSAKFSDFFDEAPIFRIPGRRYPVHIYYTKSPEANYIDAAAVTVLQIHITQHLGDVLVFLTGQEEIEACQEILTERVKALGNKIRELVVLPIYANLPSDMQAKIFEPTPPGARKVILATNIAETSLTIDGITYVIDPGYAKQNYFNARSGMESLVVVPVSRASANQRAGRAGRVGPGKCFRLYTQWAFENEMDENTIPEIQRVNLGNVVLQLKSLGIHDLINFDYLDPPPAETLILALEQLYALKALNHKGELTSTGRKMAEIPVDPMMSRMILAADQYKVVEEILTVAAMLSVNGAIFYRPKDKAIHADTARKNFFHPDGDHLTLMNVYNEWEGTEYSSQWCYEVFIQHRSMKRARDIRDQLVGLMERVEVQLTSNPGDSVAIRKAITAGYFYHVARFSKGGMYKTAKKSQTVMMHPQSCLVEDLPRWVVYHELVMTTKEYMRNVVTIDGKWLLEVAPHYYKDTEVHDATSKKMPKTLGKAREELQKDYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3V0</accession>
    <name>A0A423U3V0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycine receptor subunit alpha-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000699">
        <property type="protein sequence ID" value="ROT83342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3V0"/>
    <dbReference type="STRING" id="6689.A0A423U3V0"/>
    <dbReference type="OrthoDB" id="442503at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="2">
        <location>
            <begin position="61"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="190" mass="21686" checksum="1A4E2D340F5F7189" modified="2019-05-08" version="1" fragment="single">LVCLARLVSRGRTPLTRMFRFAIVVLALASVYGQGANGFRDSAVNSELMKLDQLFRIGDREQYDRRQTPSAAEGTATRVHIEMYIRSFGSINPIHMDYTVDLYLRQRWLELRFLNNSLTRPIDLNDPILVKFLWKPEVYFPNAKESDFHLPLPPHPSFEPPSLPPSPSPFEPPRPPSLPLPPPSLPPYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4G6</accession>
    <name>A0A423U4G6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lactosylceramide 4-alpha-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_023230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000665">
        <property type="protein sequence ID" value="ROT83587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4G6"/>
    <dbReference type="STRING" id="6689.A0A423U4G6"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="4">
        <location>
            <begin position="346"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT83587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="482" mass="54774" checksum="1359EFF49952A678" modified="2019-05-08" version="1">MRSITLSNPVIRFSTYSSGHTVILYTSPQPSDKYQRTLNKTADCSDGNIGDFTSGVSSAAPHCSRCARYKKGGSFSRRWLVESDLVAAPQEQVQAPSGDIVLVRMSLCMTRQKCVLLSIVLSTGSIILYSMVNGGPVTLLRTELRLDTPQETTEIYERENTQKLEEWQRALCKSSVTDEPEYSQTLTLPMLARDITPNASDYNVYLSETGCNPRPLYRAWCSVESFALQNPTAKIWYVITAPYVDDTDSLVTILSERYKNLEVVGADLDKMFTGTPLEKLFKSGKWTRNTPWPANNLSNLLRNVLLWRWGGLNADTDCICVRNVTHLRNTLSYDEKDRVANNAIMHFEARHRFVLATMEYLKRNFKVATWHVNGPGAASHIVQELCGTKDLSQLLSRKCDSVELMPLKNMQLYNWKEWKNFFEKGKGSKFTEDHKDAYILHMYNKLSKKRAVEIGSQTIYDSVASVVCPLTYEAAKRRAYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U654</accession>
    <name>A0A423U654_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Oxaloacetate tautomerase FAHD1, mitochondrial</fullName>
            <ecNumber evidence="5">3.7.1.5</ecNumber>
            <ecNumber evidence="2">4.1.1.112</ecNumber>
            <ecNumber evidence="9">5.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Acylpyruvase FAHD1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Fumarylacetoacetate hydrolase domain-containing protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Oxaloacetate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_022628</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>3-fumarylpyruvate + H2O = fumarate + pyruvate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26168"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16854"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19009"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57278"/>
            <dbReference type="EC" id="3.7.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>acetylpyruvate + H2O = acetate + pyruvate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16097"/>
            <dbReference type="ChEBI" id="CHEBI:15360"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>oxaloacetate + H(+) = pyruvate + CO2</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.112"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>oxaloacetate = enol-oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:16021"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17479"/>
            <dbReference type="EC" id="5.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:16023"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.5" evidence="5"/>
    <dbReference type="EC" id="4.1.1.112" evidence="2"/>
    <dbReference type="EC" id="5.3.2.2" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01000585">
        <property type="protein sequence ID" value="ROT84178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U654"/>
    <dbReference type="STRING" id="6689.A0A423U654"/>
    <dbReference type="OrthoDB" id="411064at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018773">
        <property type="term" value="F:acetylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047621">
        <property type="term" value="F:acylpyruvate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050163">
        <property type="term" value="F:oxaloacetate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.850.10:FF:000003">
        <property type="entry name" value="Fumarylacetoacetate hydrolase domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="entry name" value="Fumarylacetoacetase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007967">
        <property type="entry name" value="PRK10691.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820">
        <property type="entry name" value="ACYLPYRUVASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11820:SF7">
        <property type="entry name" value="ACYLPYRUVASE FAHD1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="FAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarylacetoacetase-like C-terminal" evidence="15">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT84178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="24385" checksum="C039F77123FAB420" modified="2019-05-08" version="1">MAAAQTQNFARFVQWGRNVVAVGRNYKDHCAELGNAVPTKPLLFMKPPSSYLEEGAGPILLPRGCTNCHHEVELGVVIGSVCRDVEEKDVMSHIAGYALALDMTARDFQDEAKKKGNPWTMAKCFDTALPVSKFLTKQELVDPNNVTLWCKVNDEMRQNGTTSDMVFSIPYLISYISQYFTLNPGDLVLTGTPAGVGSVQPGDVISAGLGDLLTMKFPVAQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U710</accession>
    <name>A0A423U710_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative B-cell lymphoma/leukemia 11A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_022372</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000539">
        <property type="protein sequence ID" value="ROT84441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U710"/>
    <dbReference type="OrthoDB" id="6616785at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000744">
        <property type="entry name" value="zinc finger E-box-binding homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052795">
        <property type="entry name" value="RREB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46451">
        <property type="entry name" value="RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46451:SF1">
        <property type="entry name" value="RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="18436" checksum="3805BEF0BCF56BF1" modified="2019-05-08" version="1">MHWKALLCPPSDFSRNQEPRALARLRRSVPPGQRVGDRRAPSRTAFAQLPGSSRPAAGHGYSSARANAGDLDSLLAQCVCPWCQRVFSKSSNLKRHMLTHTGEKPHACPLCPYRAVQKVQVIQHIPEQAQHGQGPVELPHGKASGQLMALTSLEQDHEKKKGSAAKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2011-12-14" modified="2025-10-08" version="57" xmlns="https://uniprot.org/uniprot">
    <accession>G5D053</accession>
    <name>G5D053_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_014842</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2011-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Faiz M."/>
                <person name="Zhang Z.-F."/>
                <person name="Shao M.-Y."/>
                <person name="Shi X."/>
                <person name="Muhammad S."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="JN546074">
        <property type="protein sequence ID" value="AEP83534.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01002849">
        <property type="protein sequence ID" value="ROT67088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="G5D053"/>
    <dbReference type="STRING" id="6689.G5D053"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AEP83534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="164" mass="17620" checksum="CA35B80D8583E74A" modified="2011-12-14" version="1">MGNPKVFFDIAADNQPVGRIVMELRADVVPKTAENFRSLCTGEKGFGYKGSCFHRVIPNFMCQGGDFTAGNGTGGKSIYGNKFEDENFALKHTGPGILSMANAGPNTNGSQFFICTVKTSWLDNKHVVFGTVVEGMDVVRQVEGFGTPNGSCKRKVVIANCGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A2H4V3D7</accession>
    <name>A0A2H4V3D7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Actin 1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Slow-type skeletal muscle actin 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012586</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2018" name="Mol. Genet. Genomics" volume="0" first="0" last="0">
            <title>Actin genes and their expression in pacific white shrimp, Litopenaeus vannamei.</title>
            <authorList>
                <person name="X Z."/>
                <person name="X Z."/>
                <person name="J Y."/>
                <person name="J D."/>
                <person name="F L."/>
                <person name="J X."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="MF627850">
        <property type="protein sequence ID" value="AUB30141.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A2H4V3D7"/>
    <dbReference type="STRING" id="6689.A0A2H4V3D7"/>
    <dbReference type="OrthoDB" id="6331703at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AUB30141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT69212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="41688" checksum="1FCDC90873227669" modified="2018-02-28" version="1">MCDDEATALVVDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEESPVLLTEAPLNPKANREKMTQIMIETFNTPAMYVAIQAVLSLYASGRTTGIVLDTGDGVTHTVPIYEGYALPHAILRLDLAGRDLTAYLMKIMTERGYSFTTTAEREIVRDIKEKLCYVALDFESEMTMAAASSSVEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESVGIHETVYNSIMRCDIDIRKDLFANNVLSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQSMWITKEEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LR42</accession>
    <name>A0A3R7LR42_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003774">
        <property type="protein sequence ID" value="ROT62193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LR42"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="517" mass="57902" checksum="88D78E0BDF2A8FFC" modified="2019-04-10" version="1">MLPLHEPYHTTIHRHFSVPFLSFSIVPAFPATKYPAATIHSIHTQDLTLLSLLPSSIFPHVPLPATYNPAPYHTAPSSSSSPLLFPWSPPYSPPPYLGHPNTRTYSHSLPLPSSYFHLSPLSFPPQHHTQAPSPLLPLSLFYLPLYPPFPAPYMGPPARITTWHLSVLSSCQSSNFHYDSLPPGRSYAPIHKFPSPVPFALSISGAVLGFPATIVGDRSHHRHALAPLLVSFLSYFPCTSQPRPPYHHDLSTSPRPLPSSYFPGLFPATYIPAPFHRALSFCPGLYPLLVSLVPSFARHHIVSRPSTITRHSLRRFPLFLFPVPSFPRHQYQISTIHRHFSRPPFPSPNFPCPSFPATHIAHKHPLLLLPLSIFPVPSFPASHNRQTYTNTAPSYSHRSLLPSSTALSRSLVHSSLYLQPRHHTPYLSTLLLSPFPLLFPCPSFPRPKPYPAPYTGTLDGSQSLQFITRAVDSNRPTGLCTARERNRPTGRHRIPRRQFREPTSVTLRPGTDLALRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZB4</accession>
    <name>A0A3R7LZB4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002820">
        <property type="protein sequence ID" value="ROT67333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1006"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1237"/>
            <end position="1248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1301" mass="144886" checksum="1FD1C86873AEB7C0" modified="2019-04-10" version="1">MINKSRATECLPLKHAAGVAVVVLPSRLLAFPATTGFHTAVGTAPACPNCPQLFLPVRAAFSLSQLFLPVRAAFSLCTLAPVHNLSSAPLYMTCSHAAQPRPQPRGLVSTTCSHSFGAHTHHLSFPLPRPITLPRRSSSPSIRPAVPSLSTPLVPSPSTARPFPHLQPPRSSPSTARPFPHLRPPSFLYLRPPGVPSPSTSLVPSLRPPRSLTFEPARSLTFKPPGPLTPAVALNSTHRRSSPSTSLRSLTFESAGVLTFRHPRSSTFEPCFLTSNARPFLTFRPPAFLTFDLPRPHFDRPRSSLRPSCVPHPSKPPPFPHFERRPTQLRLSLPPFSSLSTRASFLTFDARPFPHFERRGVSITSTSLVLTFDLLFPFIRTPAVPYQFDRRPDHHFDVASFLPRKRLVSPHSNAAFLTFDRPRDLTFDRSFPHFKRPAFLYLRPARPFPPFDSRSSLRRLVPQPFESPGCPLELRRRRSSRLRLPRSSPSNARFPIRHGAGRSLPSTCRRSVNSTPCSCTFRPPRFLTFDAGRSHRSRPAVPSTVRLPRSPPFDSRSAHLRPAGVPHLDHPRSSLRTARRSHFDRRRFSPSTSLVPSPSTSLVPPLRPPAVPFQLRRPRSLNLRLGSFLTFAARQRSLLTFRPPFSHLRLPGVSSTFRLHRFPTSTARRSLTSTPLRSSTVERPAVPSPSTARPFPHLRPPGRSLTFTRRSSPSTARPFPHLRPPGRSLTFNRPAVPSPSTARSLTFPSPSNPASSTFVLPHLRPPGRSTIHSLSLTATPGRSSLSARPSPPRSSPFDAGQFPHLRRPRSVTSNAARQFPHFDRGRSLNFDRRPFRHIRPRPSSAFDRGPFPHLRRPTVPSPSTARPFPQPRPHAVPHLETAACRSFTFDARPFPPFDRARRSLKLRRSLVLTSTPSSLNIRSPAFPSLRPPSFHHLSLAADVPHASRRPAVPTFSARPFLNLRRPASLLRTARPFLHLRPRRSSPSTPRSLTFDRRGRSLTFAVPRSLTRPGHLRPPGRSSTPSFPTLPPPSFLTSSSRSSPSTARPFPHLRPLVPHFDRPAVPHLSTSLVPHASTSCVPSPSTRRRSHRFDSSFPHCRSTPGLPPPSTPGRSSLRPPAVPQPSKPPSFPTRSARVLLTFRTARRFTHFGTAAVPSAFRRRASSHSTSARSLHLFDRPAFPHRSTCRPFLHVRPPGRSSPSSPGVPCTFDAPSFLHFDRPPFPSHFEPRRSLTFNRRGRSSPSRHARPFPVTFDSPARSSLDRCLLVPHTDRRAFPSPSTARPFPHLRPPSFPHLRTAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8P2</accession>
    <name>A0A3R7M8P2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006417</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001815">
        <property type="protein sequence ID" value="ROT75051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8P2"/>
    <dbReference type="OrthoDB" id="10039931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF127">
        <property type="entry name" value="BLOODY FINGERS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="24"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="497"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="550" mass="62673" checksum="5FF8E603F1ACB756" modified="2019-04-10" version="1">MKSTGDSQATVVHIRIIREKKHKFSCDFCLQSFSSADRLSQHVASDHTSLDIQDVYMCPLCRCCLLCQDDLSDHLHVKHQVLINSLQEPAICEFCGLCLDDGESLSYHHRTSHHSETNGTSVVKRVELTLRDISNMGMGNPSCKTLFQLIEYPIEKSSVDLQTVDERDGEEIVVKPKENSEIFEVSESTMPHFEIQGVFEDDNFVSVETCNDTTFPHSFENSSQNLEDEVQNFEICDNSNDEAKAVGDVQSNDSHIEMVICCNSSEKSETSSGEIILTVESDKELVWSNDFMSQVINSSGILKRNSEPIRPSGSVESSCISYSLQFDDADTRQVKVGCEQNFETRNEKESDRSCDQLINASQSIEVISSEPYLARKSRGARRKVCAICGVVFRQLGELEQHESTQHGIRVKCDLCDDTFAFSKSLRNHYLRKHSKDGNFRCEECNKSFKCRSNLWSHRFTHTSQEDRRFTCPECPQRFNTRSKLNVHLQSHTGEKKFQCGECQKGFIYQGLLLRHMRKHFPETDNFLSDDQSIYMVEVGEKASEDDTTQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBV8</accession>
    <name>A0A3R7MBV8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kelch-like protein diablo</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_003650</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May have a role in synapse differentiation and growth.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001495">
        <property type="protein sequence ID" value="ROT77674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBV8"/>
    <dbReference type="SMR" id="A0A3R7MBV8"/>
    <dbReference type="STRING" id="6689.A0A3R7MBV8"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000024">
        <property type="entry name" value="Kelch-like ECH-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.420:FF:000001">
        <property type="entry name" value="Kelch-like family member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017096">
        <property type="entry name" value="BTB-kelch_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412:SF401">
        <property type="entry name" value="FI11917P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412">
        <property type="entry name" value="KELCH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037037">
        <property type="entry name" value="Kelch-like_protein_gigaxonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="BTB" evidence="10">
        <location>
            <begin position="76"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT77674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="615" mass="69599" checksum="73482B85D05B2565" modified="2019-04-10" version="1">MASWYPDIEMEEMRSDAKGYGKERGAGPSSGVRGCIRPRHYTTSYRDTGEIKFCISEYKHDAFQMMLLMKSNQMLTDVKLEVGREIFHGHKIVLAAASPYFKAMFTGGLRECEMDTVKLQGVCPTVLAHLLCFMYTGEIVINEMLVCQLLPAATMLQMSHVIDACCTFLEQQLEAGNAIGIASFAQQHGCMDLYRKANTFIEQHFSEVSMEDEFLQLSHCELVHLIQRDELNVPDEKDVYNAVLKWVRHDEETRQPKMEQILQAVRCQYLSPRFLTEQMKNCRLLKKAPACREYLAKIFKDLTLHKPPCQKERTPNAPCVIYIVGGYSNQQSLDTLECYDVEDHQWTQLSKLPVARSGLGAAYLRGIFYAVGGRNILPNGNYHDSNWVDSFNPITNCWKQMSRMHTPRNRLGVAVLDGQLYAVGGSNGARFHSSVEKYDPDDNTWALVRPMSKARMGVGVAVVNRLMYAVGGYDGEHRLNSVECYHPENNQWTFVSSMKIPRSGAGVCSLRNCIYVIGGYDGRHQLCSVEKYDTETDVWSSVASIKIPRSAMTVSVWDGKIFVMGGYDGSQFLSSVEVYDYHRNEWSECKPLPWGRSGHASASSFHPCLLHCDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDG5</accession>
    <name>A0A3R7MDG5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDG5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="58712" checksum="4B8BB65E1CD15E87" modified="2019-04-10" version="1">MNINNTKDNNDNTKDIKNTKGINNTKGINDNTKDMNNTGDINENTKDIKNTKDINDNKKDINDYKYTDNITYNNNHIYDHVNDLYKYNNYFNNRNEYTNEKCSIYNNKHTNKYIKYTRINNYNSRNKSDINHYNKYNERNHKSCYSKHINNYFVNHNKYNNDYINNYDDYFNHHNKHINNYINKYVFYNNKKHKYIHNIKYTATPIKYSNKHLNKYNKYKYTDKYIVINKYTANDVEFFKHNNNRKYNLKYENCHLYKQHCLATECAFVNGRCNSSCGANEQALSECVRGCSCCVAADQCATTTADCKAVGGSCTLPGPDLALTCDTIDLSRCPGCACCIDCQQQTDATCSSQYNGKCKKTCGSTELQTGECQEGCNCCGCRTTNRCSSLGGQCIASFSDCQGVAIKDECSGESCFCCIPESPCSWSTPRCAQLSGRCAPSCSSGEVGVAGICGSDSCVCCTSSQNQCGASSLCSKLGGSCEQGCPAFVTSIDDLCPGDLCSCCIFLASVARGIPPWDRLSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHY1</accession>
    <name>A0A3R7MHY1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SURP motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000857">
        <property type="protein sequence ID" value="ROT82221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHY1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040397">
        <property type="entry name" value="SWAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019147">
        <property type="entry name" value="SWAP_N_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161">
        <property type="entry name" value="SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161:SF15">
        <property type="entry name" value="SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09750">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01141">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="218"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="443"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="272"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="501"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="709"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="528"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="539"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="559"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="587"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="618"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="714"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="743"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="845" mass="95454" checksum="F14C4B95375648D0" modified="2019-04-10" version="1">MASEFGRIVWEGRPKDTNNGHEELLVFGYSCKLFRDNEKAQYVDKGEHLIPWMGDSSLMVDRYDVRGALYDLKEAESGEAGDRWEGLTEEERAEEEKCDQERYLALYHDEFQYQEYQDEEAKRLISELGSDTYTYSQVGFSYDGQAVLEGGVALTEEQILEQQGALQQQAELQQQQQQQQEQYTGYFPEADEDTFVPPPDLNVPPGMIVPETVKQNKIIVKTSKFIVTQGGQMEIVIKTKQAGNPMFSFLSFDNPLNAYYKHMVSMIKSGRYRPSEEAESGRNRKESEGSEGQYLHPSLSAGIKPDLAPGTPTAIHKPTADCAYSKLIHKIKEKQKGTVVVEGKDSPAPVLVASSTPVSAASAEVGDPLKKKKLQTDITPVGSPKITSLVDYPSFNQTAEHNSDDDNNDSEMDENERCLSKEMDCRDTEYSSIKWPPPDVQMVIDKMASYIIKNGADFEAMVRSRDDPRFDFMKKDHEFYPYYRCKIRLYNEVYGDIFKEGGEDKSRSGSSEGGAGSSTSKKDKRGNNKQPSTISFSIKSREQEVNLDRHSTFPVESSSTDDEDMEEEERERRRMEREERRRKRKLKEKEERERREREERERREKEEKERLMEKPDESTDASDDNEDVYDIFKYAKNGKSTDAEEPQKPSKLNVESEKKDSDSLSATTTVLEDTHPSANLRESKQERRKKAMFLAQEKVVERRKLSISQHILNSASQSPRSSVTSPRRSTPSRSRSHSVSPGPGIPMPPREAPAPPPPPPPTLSPVQSGHTDMFDPFTYKAGTAEASSALTYKNDRTSALESCIASGTDYIDTSKSTGLQESSVLSDVLQWLSAVDISSRAAVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ08</accession>
    <name>A0A3R7MJ08_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Large subunit Rpb1 of RNA polymerase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000751">
        <property type="protein sequence ID" value="ROT83010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ08"/>
    <dbReference type="STRING" id="6689.A0A3R7MJ08"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018723162" evidence="1">
        <location>
            <begin position="24"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="22933" checksum="38CE9E6CCE5D9EEC" modified="2019-04-10" version="1">MVFTLYVHPQIVTLFALMVGVLADSVPSYSPPAPSYSPPVPSYNAPAPAPSARWNHQKFSLQIRLALEIKAIRTRVYKAVHGIGSISSTFPLSVNMSSKAVVIAALIVGAIADSVPRYSPPTPSYSPPTPVYSPPTPVYNPPTPAYNPPQPAYNPPAPAYNAPAPSIHRPGGSNATPLAETKHCPAHSCSIVMSHRIQENKRKLSFTFTLHYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJV8</accession>
    <name>A0A3R7MJV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dynein heavy chain 7, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003406">
        <property type="protein sequence ID" value="ROT63630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJV8"/>
    <dbReference type="STRING" id="6689.A0A3R7MJV8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF70">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 2, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="43658" checksum="C1B102451CBAA05C" modified="2019-04-10" version="1">MVEVMKVMGEDRSLELDGFMTSVADQMDATHETLSRWFTQIQTVFYKGFQRGQMPGFSQPGRLASFCNAAVTIMTHNLQSLCLLSVFSVTSSLCGAEPLLHDPASIALWAREPTSGGSRISGGLGDSSGCGGDGSSTGEGTTTDEGLGESVAEPEKPMVLKLHLLLTGKQVIFKPSFSEVKTSLLSLYDKMIELSLSVPRLETKLFAEWEGRQGNITPVVEEFVVDGLRKQVLKEISDSNVAPTHHSTHYQKYHALISGEAEEEVQEFMSGDHPFEAYVQKLTEFSLLRADILNSSQQVVELGPYEVHCEALVAALVSRVTNLRREMLLHLHRQYCATAETLCAELKEITERALSTPGDTLELMAHKSYMENVMENQLNTLETRVWRLHTQLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML82</accession>
    <name>A0A3R7ML82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative receptor-interacting serine/threonine-protein kinase 3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000183">
        <property type="protein sequence ID" value="ROT85792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML82"/>
    <dbReference type="STRING" id="6689.A0A3R7ML82"/>
    <dbReference type="OrthoDB" id="6373017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004706">
        <property type="term" value="F:JUN kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF293">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="161"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="42645" checksum="9DD0151E5C5F1F1E" modified="2019-04-10" version="1">MAKENLKDFLAFLDNERRTSRRPAQEVHEQSQDHTSRPLRGLKRRSSDDDEPQPKRRAAAHERDASPEPQRRKRGRSSDEQEDEGQPAQKKRVRTILIEPQPVKKSAEFQACMSDLYSIEFQAPLAQRWPVPVEVDMLRHFCERHRVPLLSLERVHELLGERAQEMIGHGSFGHAFRNTRGDLVMKCASNLFAFRTLVMEAKFMTLFSGCPGFQRVEGVCPENMCLVTKYAGPTLKQVALPAAHRLAVVEVVCRVLQNMHAEGFAHNHVKAANVCVSDSQEVTLIDFGLTMTFGCFPRLAIKWGKRLTYAPEICNSKAGICSRASDSYSVGKLLSAVLPGLETPEPARRWVAGSQLRTPNQRPYLAELLQVLGAHKGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLG9</accession>
    <name>A0A3R7MLG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001167">
        <property type="protein sequence ID" value="ROT79990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLG9"/>
    <dbReference type="OrthoDB" id="6380853at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018599670" evidence="1">
        <location>
            <begin position="21"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="182" mass="19821" checksum="7039F9222F07D845" modified="2019-04-10" version="1">MFSLAQLLVTLSLVFASSNAASPPLPSVLGRNNLVGGSPAGNLYAAPAVGPVTITVTQDRFGLRPPTPRLTTNTAFVYFEGVVVRTPVDDDVAIQTRQVARPATVTVLDQVSNIRVVTDVSVEHFTITHSYYNIMQSTYTRTTTQAITISSTLVRTNVKTDTRTETDFRTVYNTVYVQGSYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-03-27" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLH8</accession>
    <name>A0A3R7MLH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLH8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="663" mass="69721" checksum="E90D3F09F19B77AA" modified="2019-04-10" version="1">MVSFFLLPLYLRSFLSSLSYGLFFLTPHFPPSPSLLSSPMGMFSYSPSPSSLFPSFPPLLGVFSLFLLLPSSLLSYGVSAPPLQSLPPSPPPSSPMLFLTPPSPFIPPSPLLRFYRVVLLSPPSPPFPSFPRPPSLPMGCFLLLPLILLLLHRSPSSPMGFVFLSPSSLLLRPPPSPLLVCFLLSASLPPPSSFPSASLSYGLFPCSPLSLPPPSPPSLPLLWVFLTPLPSPLSLSSLPLLMGCFLTPPSLSLLPSLLPLSLWVVSYSPSPSSLLPLFPLSYGLFSCSPVSLPPPPSLLPPSPMGCSLTAPSPPLPPSLPLLPPSPYGLFLLPPSPSLPPSPPLPPSMGCFSSCLLPPSPMGCSYFPLSLPPSFPSSSSPLWVVLTPPSPPPPSPPPSLSYGLFLTPPSPSLPSPLLPLLWVVLTLPPSPSLPPFPSSSSPMGCSLLPSPPSLLLPPPSLSYGCFFLTPPLPPPSFPSPSLSYGCFLTPLSLPPSFPSSLPLLWVVSYSLPSLPSFPSFPPSPMGCFFAPPPLPPSLLPSSLSYGLFLTPPPSPLPPSPPPSLSYGCFLLPPLPSLILLLPSSPMGCFLLPPLPLPPPSPPPPSPMVVSYSPSPSLPPSPSSLLSYGLFLLPPLPPSSFPLPSLSYGFVSYSLSPLFLSLPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMP8</accession>
    <name>A0A3R7MMP8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_000269</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001042">
        <property type="protein sequence ID" value="ROT80984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMP8"/>
    <dbReference type="STRING" id="6689.A0A3R7MMP8"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000021">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025483">
        <property type="entry name" value="Lipase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000862">
        <property type="entry name" value="Steryl_ester_lip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018704614" description="Lipase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="10">
        <location>
            <begin position="46"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="11">
        <location>
            <begin position="119"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000862-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT80984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="46851" checksum="95EE2DE2557D4CDF" modified="2019-04-10" version="1">MFFPAFALVVVVVEGGGGAGGLRSFWCCQEGGRCWLVVVEGGGGPQIIEYNGYPKEVHLVTTEDGYILELHRIPHGINESKYNGKNAFKDNGQPRPPILLQHCLLCSSAEFVMNTPDKALAYLLADSGYDVWMGNVRGNTYSRNHVSLSPSQKEFWQFSWSEMAYYDMPAIIDHILNETKAKDLYYVGFSMGTTVFWAMMSDRPEYNQKVRCMAAMGPVAYVGNAKGPLARLASKAGFMEGMAKFFGKYEFLAFGPVMDKLLSYACDERVLASAMCRNFLFQIGGSNPKQLNEEFLPVLLTHTPAGTSIFTVTHYLQEIMSGNFQKYDYGVKGNLEKYNSTSPPEYNLNNVTVPVALFSSENDWLAAPKDVEKLKLELPNNVYHKVVEDPMFTHLDFVWAKDADQLVYKDVLNFLAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N003</accession>
    <name>A0A3R7N003_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002014">
        <property type="protein sequence ID" value="ROT73609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N003"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="589"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="883"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1219"/>
            <end position="1236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1261" mass="137136" checksum="D6355177AE73D663" modified="2019-04-10" version="1">MYPNRTQHKAKYQLKAASSEGATTRIIQEQTRGRDAQPIRSSNWSNQMTPRGQGSTRAPCGFHVGSKASAPNGTPRRELNSTSSNLERASHRTIKNIGRHHSALVPACKCFLEFLIGPGKGSAIVGDNLLRGTRRAENLTKQLQRTQSISVLRATTQYRSLRHAKAKLLGSFEVHKKHKRGSTHPQINVLSSGVSVASLRVPIFPSHLPSVSLDGIGPDSVYSVLCRQALQLKDLNHNLHHQGRRPRTPPLLFPLLWFRGRPLYSSLAFEAASEDAPSTLPVAFERPRTPPLLFPLPSRRRPRTPLYSSVAFEAGVRGRVASTRTPLYFPLPSRRRPRTPRCLRGRRPRTPPLLFPLLRGGVRGRPLYSSRCLRGRRPRTVLRPASEDAPSTLPVAFEAASEDAPSTLPVAFEAASEDAPPLPFFEAGVEDAPSTLPVAFEAASETPLYSSRCLRGRVRGRPRCLRGRRPRTPPLLFPLPSRPASEDAPSTLPVAFEAGVRGRPLYSSRCLRGRSEDEPASETPLYSSRCLRGRRPRTPPLLFPLPSTASETPSTLPLPSRPASEDAPSTLPVAFEAGVRGRPLYSSRCLRGRRPRTPRPFPLPSRPASEDAPLLSRCLRGRRPRTPRSRCLRPRTPPYSSVAFEARPRTPPLLFPLPSRPASEDAPSTLPVAFEAASEDAPSTLPVAFEAGVRGTRTPLYSSRCLRGRRPRTPPLLFRCLRGRVRGRPPTLPVAFEAGVRGRPARCLRGRRPRTPPLLFPLPSRPASEDAPLPVAFEAASEDAPSTLPVAFEAASEDAPSTLPVAFEAGVRGRVAFDVLPLPSRPASEDAPSTLPVAFEAGVRGRPLYSSRFEAGVLFPLPSRPASEDAPSTLPVLRAGVEAPRAPVASSSPRWPSRPASEDAPLFPLPSRPASEDAPLLRGRLLYSSFPFEGRPYFPLLRAGVRGRPPSTLPLPSRPASEDAPYSSRWLQAGVRDASFPLPSRPASEDAPSTLPVAFEAGVRGRPRPFPLPSRPASEDAPSTLPVAFEAGVRGLLFPLPSRPASEDAPPSRCLEAAFPSRELPSRPASRTPPLLFRCLRGRRRPSKASPPPGSPCVDAPCPLPFRRCLPLPSTSEDAPALNVVFRSRSIPLPSRGRPLYSSVAFEAGVGTPDDVSRCFEAGVEDAPSTLPVCLRGRPRTPPLLFPLPSRPASKDANAPALENARAWSPLHWRPASDNARTPSQIPRLASENSNAPAVDNARAWSPLRPRPASENACTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N317</accession>
    <name>A0A3R7N317_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative serine proteinase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_005513</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001711">
        <property type="protein sequence ID" value="ROT75927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N317"/>
    <dbReference type="OrthoDB" id="9518664at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF278">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR 88EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Serpin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="304"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="368" mass="39760" checksum="50DF554F34B7D3B5" modified="2019-04-10" version="1">MLARNTTGNYLVSPYSVWKALTLAYFGSSGNTQAELEGVLGAEDKISSLKVWSHLDRLYGTEQSSEDEGVVMEGRAYLSGRRSLRPCVEEILDDALRTLDFSNVYRAATDINQWTAQVTRGRAARLLQPNDLLGTNMVLASAAAFKGAWAAPFEVSSSRLQPFYATPEEPRDAVTMTQRGVFNYGESEDLGVQILELPYANSPVSLYVLLPPLSAGSRGLADTVERLSPPLLESALAAMTPAVVRVVMPKFKIESKDGDGLQETLSRLGVKDLFSERANLSVFSPEGNLRVGHAAHKAVMEVDEGGTDSSVSSSAKNFAVPPAGGRPSGEGGPLRNRVFVCNRPFAFLLRDTRAGRLLFMGALKDAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRB8</accession>
    <name>A0A3R7NRB8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_017456</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01003224">
        <property type="protein sequence ID" value="ROT64610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRB8"/>
    <dbReference type="OrthoDB" id="2019940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF54">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT64610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="26115" checksum="086DE771A7DAD345" modified="2019-04-10" version="1">MSVSLYYFHSRSYCLYHILLSVPHNGFRFAFQSSLLHHKLRTYTKFLFVRHPVERLVSAYRNKLVINSTSAADFKRRYGIKILKKFRKGDAVQNISKTGHGVTFAEFVSYLIEKRHESPQSMNEHWAPYVELCHPCFIKYNIIGKYETLEEDAEYVLRKIGAPPSLHFPPLVTSKTTALVEAHMNTLTPELRKKLYNAYQLDFKLFGYDYVKEKDYVTQENGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NZ22</accession>
    <name>A0A3R7NZ22_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002381">
        <property type="protein sequence ID" value="ROT70818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NZ22"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="147" mass="16491" checksum="3F90519A0E0ED0D7" modified="2019-04-10" version="1">MPCHVSPVESSLKAWRRGLVGARRPEEPRGCFQRSVCQANAVLAREYGGAGRVIATLMSNVGSRLLSGSDPQAVRETLDAARTGRRRRETTTHKQAYIQNDNRIARPLNRQTDGQMHKQCANHTPARVLPTRPSPKFRFPPGFYERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P2U6</accession>
    <name>A0A3R7P2U6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative constitutive coactivator of peroxisome proliferator-activated receptor gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the constitutive coactivator of PPAR-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001976">
        <property type="protein sequence ID" value="ROT73882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P2U6"/>
    <dbReference type="STRING" id="6689.A0A3R7P2U6"/>
    <dbReference type="OrthoDB" id="6354174at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026784">
        <property type="entry name" value="Coact_PPARg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15976">
        <property type="entry name" value="CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15976:SF17">
        <property type="entry name" value="CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="230" mass="26698" checksum="DD1DD0A477942A81" modified="2019-04-10" version="1" fragment="single">MGVRGLQSFLESHCGQACYSVNIGKVADEYQRRTSKTPLIVIDGMSCLRKLYGKLNWICGGQWKGYIEHFQDFYKSLKAHNIKVIFFFDGNTPERKRETWTHRRRENLKDVTTYFNIIRTNKELEHGKHFFLPTGLAAFTPLIVKDILECEVYTCMEECDKAVAEYAKKYGAMGILGQDSDYVIYNTAHYYFSINHLNLETLDTIMYDRNALSRHLHLSVDQLPVLSCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P4P4</accession>
    <name>A0A3R7P4P4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAC-GTPase activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001789">
        <property type="protein sequence ID" value="ROT75300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P4P4"/>
    <dbReference type="STRING" id="6689.A0A3R7P4P4"/>
    <dbReference type="OrthoDB" id="2218807at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097149">
        <property type="term" value="C:centralspindlin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051256">
        <property type="term" value="P:mitotic spindle midzone assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46199">
        <property type="entry name" value="RAC GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46199:SF3">
        <property type="entry name" value="RAC GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="241" mass="27832" checksum="0619002C86EB2DFE" modified="2019-04-10" version="1" fragment="single">MESLSAQFDDLMRQMQVLADPAEYKFLEFLDHEEKNRVQLRELEAEVSRLNEQATRYQKEIKSLEMKLKNAKHMLDVEKAKRITTEKEKNDLAGQIGLVMELLGRGQVNETRERLQQLQHSFTFTGTATNQRRSMRDLSPGPLSTITEDNDTMGSILSVSDIDITEDDLEETRLRSGRSFKRRSSPERQDSSKGKRRSGRRSEEIQSHEVKTQVTYYTQGDEIKKIHTEMKVKPSAPPLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6Y4</accession>
    <name>A0A3R7P6Y4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001562">
        <property type="protein sequence ID" value="ROT77158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6Y4"/>
    <dbReference type="STRING" id="6689.A0A3R7P6Y4"/>
    <dbReference type="OrthoDB" id="6372761at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="132"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="24479" checksum="D44170AFB2C41F87" modified="2019-04-10" version="1">MAEDYALIHRNVEGPKSTVKPQPTPLTEGSVSLVGDESGEKPIVILRDTAALQSLLLEGVLPLAGKTSDASVVIAGIECGHLIAPLHKLAEEDVGMFPACAVTRSMREARRVGHDPPTVARASQCVRNKDKSDQGSNFLSKAFQAAMRRMGVRHQVSSAYHPESQGALERFHQTLKNMVRIYCHETDDQWDEMVPLLLFAARECVQDTLGFSPFELVFGHESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P796</accession>
    <name>A0A3R7P796_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_019204</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003524">
        <property type="protein sequence ID" value="ROT62911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P796"/>
    <dbReference type="STRING" id="6689.A0A3R7P796"/>
    <dbReference type="OrthoDB" id="75923at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12540">
        <property type="entry name" value="RRM_U2AFBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="322"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="43"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="360"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="425"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT62911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="461" mass="53346" checksum="D8783606D62B25EE" modified="2019-04-10" version="1">MSATKSGEGLLRERDDAESASNLLRNVKQDFKKQAALLADPAYVAELERIEQLEEEAQRLEQLAAAQAKREWELRDAALHTKFLREKQKRCQQEEERAKQENALLQAVVEGLGEAENGEVTQNPEPPEGYGRREIVHPKGEPCPFFTKTGACRFGIQCSRYHDYPDQSRTLLFPNMYSHFGLEHLALDIHDSDVALEYSDSESYQHFRDFFEDTLPEFQRCGIVLQFKVCCNTSPHLRGNVYVQYSSIEAAMKARTLFNGRWYAGRQLTCLYINLERWKQAVCGLFWRQKCPKGGQCNFLHAYRNPGNAFWRADQDLHLESPKDSAEGFRCTPTPRNNYDRHQETSKTYSGSVRNARNAYRSRAKKQIKKVKKQVSRAKKQIKKVKKQVSRAKKQIKKVKKQVSRAKKQIKKVKKQVSRAKKQIKKADQEADQKVKSRSTEPRSSDQRSKKQIKKVEKQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7Y1</accession>
    <name>A0A3R7P7Y1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein-sorting-associated protein 25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ESCRT-II complex subunit VPS25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003281</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001448">
        <property type="protein sequence ID" value="ROT78019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7Y1"/>
    <dbReference type="STRING" id="6689.A0A3R7P7Y1"/>
    <dbReference type="OrthoDB" id="245150at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000141">
        <property type="entry name" value="vacuolar protein-sorting-associated protein 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.570:FF:000003">
        <property type="entry name" value="Vacuolar protein-sorting-associated protein 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.570">
        <property type="entry name" value="Winged helix' DNA-binding domain. Chain C. Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008570">
        <property type="entry name" value="ESCRT-II_cplx_Vps25-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014041">
        <property type="entry name" value="ESCRT-II_cplx_Vps25-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13149">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13149:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05871">
        <property type="entry name" value="ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT78019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="175" mass="19942" checksum="26894CCC8905AF2C" modified="2019-04-10" version="1">MTDFEWPWQYNFPPFFTLQPNSDVRKIQLDAWCALVLSWGKSNNVSQIDVTEASSLPVFRNSAISRALPADAIAVVLEELAKRGNLEWTDKSKRRGYLFWRSPTEWGQQIYTWAQSTSRINTVSTLYEINQGDETASEEFHGLDIDVLMKALKALEASGKVEIMDFGDNQGVKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9P5</accession>
    <name>A0A3R7P9P5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative engulfment and cell motility protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001240">
        <property type="protein sequence ID" value="ROT79466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9P5"/>
    <dbReference type="STRING" id="6689.A0A3R7P9P5"/>
    <dbReference type="OrthoDB" id="28413at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13359">
        <property type="entry name" value="PH_ELMO1_CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16457">
        <property type="entry name" value="PH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="23275" checksum="2E2A1F0DED5DE747" modified="2019-04-10" version="1">MQAPPIKELRKQLEPEILELIQQHRLRFLVEGTRFRYGRGMRAKDKFWYCRLSPNHKFFYYDDCDEKTVPSIDELTKKISIVDLKGIVTGKECPHMKDRTGKKSSSQLAFSLILESNNVNETNSLDFVAPEETIYNYWIDGVNALLRQRMPSVAANRDLEMLLNMEIKLRLLDAEGVTIPQQEPPIPPPPPNYNFCYQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBF7</accession>
    <name>A0A3R7PBF7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003015">
        <property type="protein sequence ID" value="ROT65927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBF7"/>
    <dbReference type="STRING" id="6689.A0A3R7PBF7"/>
    <dbReference type="OrthoDB" id="195679at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042043">
        <property type="term" value="F:neurexin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08521">
        <property type="entry name" value="C2A_SLP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04020">
        <property type="entry name" value="C2B_SLP_1-2-3-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043567">
        <property type="entry name" value="SYTL1-5_C2B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45716">
        <property type="entry name" value="BITESIZE, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45716:SF2">
        <property type="entry name" value="BITESIZE, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="106"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="31738" checksum="BF183A6EB2128DD7" modified="2019-04-10" version="1">MPAPPCTYVKVYLLPDKSKSGKRKTKVKKHTLNPSFDEVLRFTTTMSELDSRTLWVSVWHSDMFGRNDFLGEVIIPLADTVFDDVTPKWYPLQEKTEPMDDLSYSPRGDLILALKFVPPDAVTGRKARRSRGALHVLVKEAKSLAAIRPHGTADPICKGLLLPEKGKASKQKTSVCRKTLNPTWNHTLVFEDTSLQELTERSLELSVWDHDRLGTSQFLGGCRLNLGKGKHGGRAVEWMEAAGMEVKLWEQMLERPNLWVEGSIMLRPSMDKPIYSSSMTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCP7</accession>
    <name>A0A3R7PCP7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Farnesoic acid O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002883">
        <property type="protein sequence ID" value="ROT66822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCP7"/>
    <dbReference type="STRING" id="6689.A0A3R7PCP7"/>
    <dbReference type="OrthoDB" id="2142040at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022041">
        <property type="entry name" value="Methyltransf_FA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36695">
        <property type="entry name" value="AGAP008648-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36695:SF12">
        <property type="entry name" value="AGAP008648-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12248">
        <property type="entry name" value="Methyltransf_FA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Farnesoic acid O-methyl transferase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Farnesoic acid O-methyl transferase" evidence="1">
        <location>
            <begin position="213"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="342" mass="38582" checksum="21C2C61F4158EB7B" modified="2019-04-10" version="1" fragment="single">IPESPQLRPRRDGSGVYAAPCCHPSEGPPKLIIRNTAFLAHDAVPACLHLSPLNLPGLGESWKGDDWASYGTDENKQYRFRDIKGKTLRFQVKAAHDAHIALTSGEEETDPMLEVFIGGWEGAASAIRFKKADDLAKVDTPDILSEEEYREFWIAFDHDVVRVGKGAEWEPFMSATIPEPFDITHYGYSTGWGATGWWQFHSEIHFQTEDCLTYNFIPVYGDTFSFSVACSNDAHLALTSGPEETSPMYEVFIGGWENQHSAIRLSKEGRGSGEDMIKVDTPDVVCCEEERKFYISFKDGHIRVGYQDSDPFMEWTDPEPWKITHIGYCTGWGASGKWKFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDT0</accession>
    <name>A0A3R7PDT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dnaJ protein-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003664">
        <property type="protein sequence ID" value="ROT62490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDT0"/>
    <dbReference type="STRING" id="6689.A0A3R7PDT0"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="253" mass="28146" checksum="E3F51E03B332B2AC" modified="2019-04-10" version="1">MALKYHPDKNKSNDAEEKFKLVAEAYEVLSDKKKRNIYDQYGDEGLKGGMPGGRSTGGTHFTYTYSGDPRATFEQVFGTNNPFSHFFNMGVDGMALTTCLRTCWLAGISQEEDHEERAADGGGGSTLREEKILTIEVKPGWKEGTKIIFEKEGDQSPGKIPADIIFIIRDKPHPLFKRDGANLVYTAKIPLRDALRGTLVSVPTLTGQRVALNFNKETTKPQTTRRLQGYGLPYPKNRRGRVILSSTLISNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFD1</accession>
    <name>A0A3R7PFD1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Putative paraplegin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_017499</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003233">
        <property type="protein sequence ID" value="ROT64565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFD1"/>
    <dbReference type="STRING" id="6689.A0A3R7PFD1"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005745">
        <property type="term" value="C:m-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000003">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000277">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000033">
        <property type="entry name" value="paraplegin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050928">
        <property type="entry name" value="ATP-dep_Zn_Metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655:SF8">
        <property type="entry name" value="PARAPLEGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="211"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT64565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="647" mass="71700" checksum="675986D1384A0392" modified="2019-04-10" version="1">MLAKAALWMLTAYMFIAIISLLFPGSNQPEIARYVSWNEFVHQMLAKGEVEEVIVRPDLDIVTIILYEGAVIKGKKIDQRTFHMNIVDLQHFEERLRESEAKLGIRSDQGVPIVYERSGDTAGRLLASIIVVAIIVSLLSRNMNIKGPLSMEGMSQMTRAKFTIIDPLLPGSGRGVKFADVAGAREAKQEVMEFVDFLKNPDKYRELGAKVPRGALLLGPPGCGKTLLAKAVATEGQVPFLAMNGSEFIEMIGGLGAARVRDLFKEAKKRAPCIVYIDEIDAIGRKRSSGQGGMDGGSGESEQTLNQLLVEMDGIGSKEGVVILSSTNRLDILDKALLRPGRFDRHIMMDLPNLEERREIFEHHLKSIVLEKPSTYYARRMASLTLGFSGADIANVVNEAALHAARHAKKVVTANDLEYAVERVVGGTEKRSQALSPEERRVVAYHESGHALLGWILEHTDALLKVTIVPRTNQALGFAQYAPKDQKLYTQEQLFERMCMALGGRVAESLVFNRVTTGAQNDLEKVTKMAYAQVRSFGFSDNVGQVSFPEEETREVGRRPYSQKLAATIDEEASRLIFAAYKKTEEVLKANMDKLTLLAESLLQKETLNYDDVEAILGPTPYGQKLVIEPLQFEGEINKWKDAGKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFT4</accession>
    <name>A0A3R7PFT4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002437">
        <property type="protein sequence ID" value="ROT70371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PFT4"/>
    <dbReference type="OrthoDB" id="2157866at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="775"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1285"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1366"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1555"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1790"/>
            <end position="2260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2335"/>
            <end position="2358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2376"/>
            <end position="2433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="779"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="920"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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            <end position="1131"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="1166"/>
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    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
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            <end position="1298"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1300"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1378"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1389"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <end position="1516"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1567"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1669"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1698"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1868"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1951"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1968"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2017"/>
            <end position="2032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2039"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2061"/>
            <end position="2072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2073"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2102"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2113"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2134"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2157"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2167"/>
            <end position="2194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2212"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2376"/>
            <end position="2386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2433" mass="272157" checksum="806883870725D665" modified="2019-04-10" version="1">MYSREDIREQYCINDKELHALEASRRKPIFGCLTSGNTQVSPCKKKSLLPACLRGRVPSDENVYTKTSSAAPSAHASPAHRKHQHEHDQIDYEDDSYFKRRPKTICYTDPKRLASFDDSLARSSRVSRPRSEVGSATYDSYHADDVESDAARRPTQLAITSGDHHSTEFYHGDSHKEGYPLTRSAFTQPNTPDLSRHSSRHRQVTTPALFPLEDRPQKHVSFQKAMSRSATVAVLEEQVMSRQDSGRASVKSGGSRSHERLLDGRRTPDYMEQRALDQLLAPSGGGKHRKGQAREVTRRSGGLTVESEAGSRSRSRTPSLRRKKVEKKTVGVQTDEMFEMEVEEERMKVGRGPGVLEEAREGARGLGVPEEGTYGVGGRRQKKTKKKAITIVEPPDVFSKREDPPPPARQRKEEAEASPREVAAENKKPKKTKSKSGKAKAKDGAPSEAVPAPKGKAVERQEQRPSRRPEEVPLSPVAPRIEKSVKDKGSKVSMAMQTDDAVETIFSDRSIFLTDDLDTSTDWREESSIDWQTSASSLAWQTDRSSFAWQTDASSGNKYTGDNSFALESCEEQENNEDLLNMDVFLIRDRRNKECSRQNMNQNAAQESENETNQNVQWDGGGPRSRDPVDGKAQRKVAAKEVKHKGKTQHSDKEDIEGKQRLGEEKNSRIGRTEKESKKRDGPQTSCKPPVLRPPNDNDDEVAEIHEEFRKNSNNGKEGLQMGDKVIERGILKEQIEQEEENEEMQQEMQMDDETNAMVRRLRFRRQMAEEFLNQQAEDLGKAREQASREPESRGHNNLAATLPNRRNQKLRFAREVVTPEKQLCTQESYGTWPQRVTENQRTDDINLKAFPAFSPSAASGGRKSRNQAPEHKRSHLEINLVIRDKDENPKNTFTNEHEGKTSISRPSTAKPQQVETSDEYPRSDHDYGGSRLKKIAPKSDPSRTPQRKKKTGVRELIEPTASNKTGNIEHEVQPRLPPKNQGERGINRLTYIRDEEKQQCYCTDTSSTVTNTDSVGRRVRRIKKKALAVQTEEATVDSQRAQEETKVEVEGKGDRAREITALGSNPTVAEEHKESGASQPEVTSLRRKRSVKRRSRCIQADLSLEDQIEAISSQENSQLPYSSERFNPSVPTDVGQFKGNVEIDAGRSDQEKLEAQAPKDDKEQRSGTMSSSIRRMKKVRKTVATTQTEEKAELEDGLFIPPAFQPDSVSIRTSSLRRIRRAQKATVAVQTDDVIPVCFDNLHLSLLDFKGGQPLAESLGPPRHSDSLIYMNIPAALLEVVESGNDADVSDSEEGDGDAQNKDSEDEDFRIYNKVTEEDFNTTSHVITRLSPGDVTVKISSRRSSYTEAYKGHDESVCLLPCESGVEEGVEGPQESEGAEEAEDTEDEAKRGKMYREQLLKNENSRECKNVEEDESQTGREEAKGKTRDISESRKKDITWRESLARDGDEEKTGSPKDGWMWQQVNDEETESSGTTDNELAVGVAQGTETDKSRRERETKNRELKKAKSQKDDKPDILKELYVDKKKDELIPDVEMANKTHAIKKEEIEKDGGIKKEKRTRIRQATAREKEVDPRGREEGEVREKVKNIPDVESGRTKVEKESMNRKEGGEIGKNEENEEKNEAEVQKPGEGEMLKEKSGMKAVVEDKERKIPNEEKAASHTEGQGDAPEREAKGTREMDEGRRGTRGRRVLTPRQKFSEKRSRHEKGDFSLTDDAQVRITDPAASPGPVVKEAADGNAVSAKDNRPSGGKPVVGDMKRDNKNSASPVHLEEACTESEVQISTRIADKPAAMREDGAETNAVVPIANFSEPEAETKSDGLEMNSHPQGELDEGMGKQEPEFEESSEVNVSTKEEDENENDDMTQFKTNKDAEREVENIQEEDTKKKTINEDHSDEGEAKMKATKAKMEVETIDELEKSESCMADEDDGEQLKITGKEEARDILDGKEVTEETLADPELTDNEDWEERSETTSNRKEEGDLLPLNLTEGSRDTFAEDDDECIVITYRPPQKPVQRGRPREGAGVRGEADGADRSPSASRRTDDQGDDGKDVSSKEGEEAKKKKTRRSKRKKVKDGIDANKKEGEETHVTDIENVSLKGEDKKKKRPRQRKNKAGKEKVPQTEIKEASKMGVQEGESRAADQESKSSAHPPTRRWAEEVEEEGLDEWGEGKKGEVNEGKDNRGEKRAGDASRVAERNPLPEVKAGEAGATLAVEEDFLTESDALETEEDTSYYEEEGEGSSRYEMESEEGGEGGGEQNAFEEYLLLREDEGIEEMQTVDRIFRQVFEDYNDGEFLGEGDVSEGECNDSLHFLGSGRGREEEAQGKSKTFTGVRVEGDELEVESKNDLDVQSSRTSVPPGAEVMQARLSASLPLLTNPSFPLSLSADNPLQLPANKISSPATPSYDPPNSQSLPPPLLPKFPLSLPANKAPSPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGM3</accession>
    <name>A0A3R7PGM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002333">
        <property type="protein sequence ID" value="ROT71177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGM3"/>
    <dbReference type="OrthoDB" id="6369419at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="629"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="796" mass="86244" checksum="026CB699A74EBA95" modified="2019-04-10" version="1">MLLPRPQRRTGRRLTSAGHSDSSGLSSPSEDRRPLNRKPPGYRGANQSFRESSEFRVGEAVRELSPRGPMKNSTSLPHFSSGKDSGFDETPPVGDEFATSRGGRSGGAFIVSGVFNDSSRMFIPAPPSPTPDYDDDGESDGNESDILQGSQFYVVTDQQGEPVKKKLTNRDSLSDDSLQNAPVTTKSTSKSSTPPKTPSTPLQSMMRAFHKGLPDLEQENGFSDDSLEDSVTAQSRPSTISQKPHRPTSMESLVSMESSTASFDYMNAGQAKNSSYGRARSRPNSADTGAQKGGNVRDRKDLNGKVKKSTPRSAENGIGQKGNLSNKDSEKNIEESNNFSRQSSRESSHSSGSTSSKPSEKFDTIRHMLKEGLIEGLDESPPTFKPPPPIKKTPNGVHAEDRADSGLGSAVSTTRTDESGGSDNRSDFSGTPPSILSPQDGDATKKGRPETKRGKETIRSRTSIGSEDMERNRDEGDEVEVMMQETMEIPPPPPPRDESMHWTPRTTTPLSQKDSARSSLRATPTTPSTSKNSSWLHNASKEEMVEISSANSPLPAGEKITHVDDLYGQHEHVGNGNEVSSAINGSLASQYSIQDNDNPLTDRDFLENLKNLEPRPRPDTLAVISEDQGSIGSKSSRSGRLLSRLADSVRSGSRTPTPSSSNSSTTRATTTKLTSTSRSSTRIHGDIIRDPWRSSLRESALPSPQEYARLPSLSPSVVPLTRDGSGRFRSIEDLAEAVSEPTQQEVTLTGKKKKHSTLPPNLTPADMKKENKELRRATSLMVGKKGKEYESAGNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PH21</accession>
    <name>A0A3R7PH21_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002285">
        <property type="protein sequence ID" value="ROT71508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PH21"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="668"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="694" mass="74608" checksum="352821E695A949D9" modified="2019-04-10" version="1">MTPSSPAYSSHEIRHFYQALRDASIPGLPPSMLARSPDASKVRPMLARSPASKGVFSRSLVACLSMLARSPASKGSLSRLSRRLPPSMLARSPQCVKRESFLASLVACLPPCCTSPASKGSLFSPLSSRLPPSMLARSPMRQKGVFSRLSRRLPPSMLARSPDASKGSLFLASLVACSLHAGTFAHASKGSLFSPLSSPASLHAGTFARCVKRESFSRLSRRLPPSMLARSPVRQKGVFSRLSRRLPPSMLARSPNASKGSLFSPLSSPASLHAATFAQCVKRESFLASLVACLPPCWHVRPMRQKESFLASLGLPPCWHVRHASKGSLFSPLSSPASLHAGTFARCVKRESFLASLVACLPPCWHVRPSKGSLFLASLVACLPPCWHVRPMRQKGVFSRLSRRLPPSMLARSPSASKGSLFSPLSSPASLHAGTFAHASKGVFSRSLVACLLHAGTFAQCVKRSLFSLSRRLPSLHAGTFANASKARLFVACLPPTFANASKGVFSRLSRRLPPSMLARSPNASKGVFSRSLVACLPPCWHVRPMRQKGVFSRLSRRLPPSMLARSPNASKGSFLASLVACLPPCWHVRPMRQKGVFSRLSRRLPPSMLARSPNAPKGSLFSSLSSPASLHAGTFAQCVKRVFLASLVKKKLSRLSRRLPPSMLARSPSASKGSLFSSLSSPASDTTVIARLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PH79</accession>
    <name>A0A3R7PH79_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 20">Polypeptide N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="20">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Protein-UDP acetylgalactosaminyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_010013</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23956"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:12788"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:53604"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:67138"/>
            <dbReference type="EC" id="2.4.1.41"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:52424"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:67138"/>
            <dbReference type="ChEBI" id="CHEBI:87075"/>
            <dbReference type="EC" id="2.4.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 20">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Golgi apparatus membrane</location>
            <topology evidence="2 20">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 20">Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="20"/>
    <dbReference type="EMBL" id="QCYY01002268">
        <property type="protein sequence ID" value="ROT71654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PH79"/>
    <dbReference type="STRING" id="6689.A0A3R7PH79"/>
    <dbReference type="OrthoDB" id="6159198at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23439">
        <property type="entry name" value="beta-trefoil_Ricin_GALNT10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02510">
        <property type="entry name" value="pp-GalNAc-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000011">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000029">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045885">
        <property type="entry name" value="GalNAc-T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF134">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 20" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 20" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 20" id="KW-0430">Lectin</keyword>
    <keyword evidence="17 20" id="KW-0464">Manganese</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="22">
        <location>
            <begin position="470"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="37"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00050905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00052209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU361242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT71654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="609" mass="69588" checksum="E118449297AB4BC0" modified="2019-04-10" version="1">MRLRRNVRWWAKVSVAAFLFLLGTYLTVRQAQQDASLGDKRVVRVQEDEGSESDSGKNPGSRARKDVEQDKLPEPPGYKDWNNYELLEREKSQVGPGEQGQAFILPAGHQSQKDQLYKVNGFNALVSDYIALNRTLNDLRHPKCQEKVYLKSLPTASVVVPFHNEHWTTLLRTAISAINRSPESLLAEVILVDDASTKEFLKDKLDNYVKAHLPKVKVLHLTKRSGLIRARLAGAKVAKGDVLIFLDSHTECTTNWLPPLLDPIAQDYRTCVCPFIDVIDFETFAYRAQDEGARGAFDWELFYKRLPLLPKDKENMPEPFKSPVMAGGLFAISTKFFWELGGYDPGLDIWGGEQYELSFKIWQCGGTMVDAPCSRIGHIYRKFAPFPNPGMGDFVGRNYRRVAEVWMDEYAEYIYKRRPHYRNIDPGDLSEQKAIREKLQCRPFRWFMEEVAPDLVKVYPPVEPPDFASGRIQSIVDSNLCVDTRYKRHGDRFGLQECGHGGEQSFHLTWHKDIRPGKRSVCWDVSSGDAQAPVLLYNCHGMGGNQMWKYDPDKKWLVHGGNPRCLDCNPGNKELFVAMCDPSRDTQKWSFEKYDAQRLAKWDQAGPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHM3</accession>
    <name>A0A3R7PHM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002886">
        <property type="protein sequence ID" value="ROT66793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHM3"/>
    <dbReference type="STRING" id="6689.A0A3R7PHM3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="49628" checksum="3CFAEE1F88A22051" modified="2019-04-10" version="1">MGGLGARRPRGRDAFCRTDKYRGKRNKQIVSRCHMSTAEREEIDGERKKWSLPGPVSTGNPSSAQYPRGIHPPPSIHGESLLREIKMISTHIAARKEDGRRYESRGRRDHAPLVLITARGGDATRPDLNPNELDIELALYVTRRISNSPYIQLTPHPTHTTSKLPHIQPALYPIHTTPTAQYPNSLDTHLQSPKTRTEIMTDRRKPGTHDPTGDTHPHTPLAPSPPTPARPPWHPFLPLPARTTMAPFPPTPAPPPWTLPSHSGPTTMAPFPPTPADHHGTLPSHSGPTTMGTLPSHSGPTTMALLPPTPARPPWTLPSTPPDHHGNTPGPGYRPTHHGTFPPTPATTIFPLLRQDGGIIRLPFTPLVAKPNEQSGPGRQPFRTITNEMGNEVRVMSLPAPSRIMIFIGGWRSSSRVADPRPSTSKPEGNVAAPQVVPEPGVPLTLGLGSRRTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMH7</accession>
    <name>A0A3R7PMH7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002314">
        <property type="protein sequence ID" value="ROT71309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMH7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1231" mass="133352" checksum="96319B4D861B9A7A" modified="2019-04-10" version="1">MSASPPTPLPNSHPSNPLPNPPHALNSSSSTNPSLFPSPASPSAPPCPPPPHPPLGISAPRGHLSTIFPFLPSASVSLLICSFTLSASPSPFTLSLSFSPFIPFSFLHLCLFSLSFTLYALLPSLPFLIPSPFPLSPSLSVPFSLFLTLYFLLLSLFLCFTPSPFPLPSLFPSPSFKSSLPFPSLLNLYSLLPLSSFPSPSPSPLFLLGLPSLTPHLFPFPPSPSSLSQIFPTLPPSPSPSIPFFSPSPFPSFPHPFSFLPLPLLPSHILLPFPLSSSPSIPSLFPLFPFSPPSPHFHFFLSLTPSPFSLPPFPLLPPSYPPYPSPLFLTLYSLLSSVSFPSPSPSPIFTSPSPSLPHPFPFLPFPFSHPLISSLPFPSFLTLYSLLSLPLFHSLSSPHFHFSLSLTPHPFPFLPSPSPSLISSLPSPLFLTLYSLLSLPLFPSPSPSPHFHFSLSLTPSPFSLPSFPPSPSLISSLPFPSLPHPLFSLSPLFPSVLTPFSLLPLPHSLTLSLPSFPLLPPPISSLPFPSLPHPLFSSLSPSVPISLSLTPFSLLPLPPTPHLFPSFLSPFSLPHILPTLPSLPHPSILFSLSLCSHLPLLTTIFTSPSPSLPHPFPFLPFPLLPPSYPPYPSPLFLTLYSLLSLPLFPSPLPHPFSLLPLPHSSPFSFLPFPFSHPHTSYPSLSSSPSISSLSPSVPISLSLTAHPFPIPSFPLSPSPHILPILPLSSSPSIFFSLSLCSHLPLPHPIFTSPFPSSLTFSLLPFPFSLPHILPTLPLFSSPSILFSLSSVPISLSSPHFSLSLSLTPSPFSLPSFPPSPSLISSLPFPSLPHPLFLFFSLLCSHLPLPHPIFTSPSPSLPHPFPFLPFPLLPPSYPPYPSPSLPHPLFSSLSPSVPIFSSPISLLPLPHPHSFLPSLSPPPPHILPTLPPSPSFHKGLHSLKSFLSRSQTASLNSLSGTWLSRTDEVPALFHSDLLGEIYVPLSPFPFHFCPNPITKHRGISPKSEKKKISLRGLATLAPPIRESDPMTRDSSAPERIASSHFGLLKELLSPQRTKTALILAVIKRLALCPQLQMSIDVQIDVAVNTSWFYSSKYTRKDILPLPSPSSKPSLPIPFLPAYYLLYPPSSLPFLSSLPSFIYSSPPPFLPCLSFSSSLLSFLPTPSAYLLSPPFFLSILPTPAQYPHSSASLHTPPLFLSLPAYSTYSISPFLPFSRLSFTLPIYIIYGPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSA0</accession>
    <name>A0A3R7PSA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative dynein intermediate chain 2, ciliary-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_000260</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001041">
        <property type="protein sequence ID" value="ROT80993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSA0"/>
    <dbReference type="STRING" id="6689.A0A3R7PSA0"/>
    <dbReference type="OrthoDB" id="6372332at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="372"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="43"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT80993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="531" mass="59065" checksum="3A13595998E1947A" modified="2019-04-10" version="1">MTSTTQTDPPPGNIFAAAASLSTIYDAYEKDYMLVLAKQRELEKQKEMEDEKEREKSGKAAPKGSPDPIVLPATPPPSRPSLGGEELDLDPNTVKMTERLVNQNIYDEITQDFRYWEDASDEYRQLEGSLLPLWRFSCDKSRSLVVSSLSWNPARHDLFAASYTPGGQADQYVKLRTLSLFPLHKASESESEGRICLFTLKNPGIPERMLVTPRGVMSVQFHPSHESMLVAGHSDGTVTVYDARHDASTGRLSSSTTSGKHLLPVMQVHWVTTEPGENMSFYSVSQDGRVSQWFVRTTSLKYEDVLNFHAAEQTQDHVAPSSKTELEDNVPSGTATCIALSPERKDVLLFGVDTGALFQICTSDTAHAITRYRAHLGPVTAVAWNKVHTMVFASCALDWTVKIWLQYHLSALITLDLGGPVMELAWSPSSSTLVVAVTDEGRVFVYDLFLRRYHPLCVQNLLQRRRSSLTCVALNPSQPIVLVGGEKSYIVAFKLSPNLRKPHKDAKCADEEGAKAIELCKMERIIATCRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTM6</accession>
    <name>A0A3R7PTM6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat shock 70 kDa protein cognate 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001615">
        <property type="protein sequence ID" value="ROT76737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTM6"/>
    <dbReference type="STRING" id="6689.A0A3R7PTM6"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000135">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000134">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000003">
        <property type="entry name" value="heat shock cognate 71 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="672"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="675"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00072095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="700" mass="76614" checksum="29F8A22E08FA3B13" modified="2019-04-10" version="1">MNVTSLKRRALIGSSARPKLLEMSSTLGSATGGLRHHSSLDDAGGHTRSRGRLDSFQTLDIMVKAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFEDSCVQGDLKHWPFHVISDGGKPKIAVEYKGEKKTFFPEEISSMVLIKMKETAEAYLGGIVKDAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRLVNHFMNEFKRKFKKDFIENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYDGVDFYTSVTRARFEELCADLFRGTLEPVEKSLRDAKMDKAQIHEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILVGDKSEAVQDLLLLDVTPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELAGIPPAPRGVPQIEVTFDIDANGILNVSAIDKSTGKENKITITNDKGRLSKEEIERMVHDAEKYKEDDEKQRERISAKNSLESYCFNMKSTVEDEKFKDKVSEEDRNKILEACNESIKWLDANQLGEKDEYEHKQKEVEGICNPIISKMYAAAGGAPGGMPGGAPSGGASAGGPTIEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PV80</accession>
    <name>A0A3R7PV80_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001445">
        <property type="protein sequence ID" value="ROT78042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PV80"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41820" checksum="2A925A033757B4CB" modified="2019-04-10" version="1">MLLFPLSPFFSSSFSLLLNPYSPFSLYLPFSFSLPLFSPLLLIFRPPYLSFCLSSFLSSFNFSLSLLLSFFFPLLLTSSLSFSLPLLILHFPYLSSSIFPSSPFRSPFPIPPLPFPFLSSYSLTMLLLLFPFLPFSSLPLTSPSPLLTLFPLLFPFLSPSPFTLPLHLPYPHLSTSFPPSSPTPSLFTLPLHLPCSYLSSSFSPSSLSPSLFPLPPHLPYPHLSSSFPLPFFLPSLTSPLFHLPLLLPSPYLSIFLTHISPPSFPTPLLLLLSSLYLSIFLVHISPPPFPLPSFLLFPSLTFPSPLPTSPLLLSHLLSSFSLPLPLPLPYPHISSSFPSSSPPSPFPYLSLSAIKASFSIQTINRDFNLTTMLMLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVU1</accession>
    <name>A0A3R7PVU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_022662</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000587">
        <property type="protein sequence ID" value="ROT84167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVU1"/>
    <dbReference type="OrthoDB" id="8190074at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF27">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="556"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="617"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="657"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT84167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="675" mass="72637" checksum="90629F37A2891B1C" modified="2019-04-10" version="1">MARLPRPSGAYPGCIRTSRWCVYLAHLGAATFGDACRGFSRGVGSLRPTTHQALESPPSVSSLPIIISPQKEISVLDPPSLCSLSLLSFLLLSLSPLPSTLTILPLHFPFSLLSLTPSFLLLSPLLPFSTFLLFLFPFSIFFLNSLHSVLLLSPLLTHLSLMTESKPQAPPPTAARLEEVEPPLSLPAVEGPVGKTAVAPSILSAEHLHAQIKNVGGDSWRVGADAPPPAIPRDQDKKLPDEDEAKGAYKTYYTRFWILAVFSTLALPVQSTVWGTFGPILDSAEAAFGWTDATVAAFPNWGPVVVVTFTLPMMWFTQKLGLRLGMLACATLIFAGTLVRCFTSEPFIFTVLCHVGAVLNSFAACMTLSLPAMVAAVWFPPDERITATAVGALMCQLGGAAMYMGPLVVRSPGNGTSPEDTSETLAEDIRGDIMTLMYIPEDKPSFLSGIKSIAKNVQLLLVLGVYSFSFGVPVVWIGVLTFSLRVIDIHQEQAMGVAVVAVCVSSVAAFVIARITDKMYGHLRVTIIGLLLASAACFLWFVLISTGVIEPSLVQVYMSVTGGVSFEYASVPLLVELAVELGYPIPESVTGAALTFLFNVVALVFLGLFQIPSDYMWVSYVLLACVSLTIIPLMFVKETHKRSEADRKEISHITGSAIVCVTLFYCGLPTLPAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWB5</accession>
    <name>A0A3R7PWB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004109">
        <property type="protein sequence ID" value="ROT61553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWB5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="528" mass="56380" checksum="1AAA0E4788010548" modified="2019-04-10" version="1">MILYVSVYYFRLRLSPSLPLPLSQYLSLSLSLSLSLSLSLSSLSLSLLSLSLSLSLSLLSLSSLSLSLSLSLSLSLSLSSLSLSLSLSLSLLSPSPLPLLLSSFLSPFSLFPSFPLSFFPFPPSLSPFFSPFLLPIPRSFLFPPFLPFPPPSILTPSFHPFNPSLLSLPSSFLPIPLFHSPLPPSSLPSLPSSPSTLLSLSLPPPFLTFSLPSFLSISFSFLPSSLLPIPFFLSPSLLLPSSLLSPSFLPPSLFSSFPPPFLFFHLSFHPPSHLPSSPSSYHPSLPSLFILRPSPLPLISLSPSPSPPLLSSPLSSSSSPPPFSILLSSSLPPSLPPSFPLPIIPPPSIFPSLPSASPPFFLLPSLSLLPPPSSLLPLPPSHPSSHLPLLLPLPSSPPSSFLLPPSSLPLPPILPPLFLPPSLPFDQRPCPLAHLALRPSLLPSPSLPSLPPSLLPPFHVLFSLFCVFFSSPFHHFCLSPSPSPFHTSCHLPSLASRLPPFPSLTPLTSPPPLPLPHPNLPAPLPHHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXA7</accession>
    <name>A0A3R7PXA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019779</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003703">
        <property type="protein sequence ID" value="ROT62387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXA7"/>
    <dbReference type="STRING" id="6689.A0A3R7PXA7"/>
    <dbReference type="OrthoDB" id="283091at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 9 11" id="KW-0349">Heme</keyword>
    <keyword evidence="8 9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="2"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="104" mass="11378" checksum="93265E51A5BA0564" modified="2019-04-10" version="1">MGDIEKGKKIFVQRCAQCHTVEAGGKHKTGPNLHGLFGRQTGQAAGYVYTDANKSKGITWASDTLDIYLTNPKKYIPGTKMVFAGLKKKGERADLIAYLEDSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZE3</accession>
    <name>A0A3R7PZE3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017673</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003257">
        <property type="protein sequence ID" value="ROT64385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZE3"/>
    <dbReference type="STRING" id="6689.A0A3R7PZE3"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017071">
        <property type="term" value="C:intracellular cyclic nucleotide activated cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005222">
        <property type="term" value="F:intracellularly cAMP-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005223">
        <property type="term" value="F:intracellularly cGMP-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050866">
        <property type="entry name" value="CNG_cation_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45638:SF11">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="158"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="23"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="351" mass="40101" checksum="AA48425048599D24" modified="2019-04-10" version="1">MLGKTSRGTRNISQFENLAGIPEEPGISLWPSSSTTSLPSLQKIPEKRSGENGFLSPGSLRNSLADDTCSEILRVEQRDAEEQLNRKSSPLSKLVATLQRIRSWTTRENHQEPERPDSFLEKMAMAGQVREADDTQHAFCCGVMRGDFAIDTTKPAHYKWLFVMTAALLYNWVMIVGRAVFWELHNLSPALWLSLDYICDGVYVIDMVIRAHEGYLEQGLMVKDPSKLRKNYIKSWGFKLDLISILPTDLVYLLTGTNCDNYVPGPVLVRVNRLLRISRMGEFFDKTETRTNFPNAFRICKVVLYILVIIHWNACFYFAISYAIGFGTDGWVYKNITIGRNGTFSHQYIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1E4</accession>
    <name>A0A3R7Q1E4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Protein-tyrosine sulfotransferase</fullName>
            <ecNumber evidence="2 5">2.8.2.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_015967</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16801"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:11688"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:65286"/>
            <dbReference type="EC" id="2.8.2.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the protein sulfotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.20" evidence="2 5"/>
    <dbReference type="EMBL" id="QCYY01002998">
        <property type="protein sequence ID" value="ROT66036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1E4"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1E4"/>
    <dbReference type="OrthoDB" id="545675at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008476">
        <property type="term" value="F:protein-tyrosine sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026634">
        <property type="entry name" value="TPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12788:SF10">
        <property type="entry name" value="PROTEIN-TYROSINE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12788">
        <property type="entry name" value="PROTEIN-TYROSINE SULFOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT66036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="17376" checksum="27390121F4F83C3C" modified="2019-04-10" version="1">MNTQCSELGPDRCLPVYYEQLVLHPEEWMKKILTFLEVPWDDAVLHHEEFVNKPGGVSLSKVERSSDQVVKPVNLDALSKWVGQIPKDVVEDMANIAPMLAVLGYDPNGNPPNYGSADPIVANNTKRIQRESNVWQDRAQEVLSLSKHRRGDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAI4</accession>
    <name>A0A3R7QAI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004004">
        <property type="protein sequence ID" value="ROT61755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAI4"/>
    <dbReference type="OrthoDB" id="6372189at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="922"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1026" mass="111096" checksum="E33EBA51CDED6C68" modified="2019-04-10" version="1" fragment="single">PEQWPPGGWVASWHVEESSRSHLSDNASSQNRFHSSLQLLSETSLQPRLSLSDHNTTSSSAQMGEDCYTPQERTSCTSAANSSTNTATTTCWYDIITSLSLTTTSQTAAAHYHQKSGGHQTNIADSPGGSGNLEDMGTSLAPRGESGMQKFSPLSLESAVTSTSSSPEQKNCHVSQSTMDNLDLKDSKYPIDLAVFTCEDKSKGALNKNLAKVSSKVSNSERTNSNDGSTAEEGAEVTTKDEGYSTMSSDVQAELYKERRNAQGHKIVASLDRHVSVKDLAERTASTAEVLEEACNTRSLKRSSAQASLKRANLRKREEQPTSGSSEELWPLEEDHRKYLSPTYSHAELEDWSLDLSSEYLSGACGEGEGSESVGTSGAHHGSLPSIQEATPELEEDNNEFLWNGATYFKTDLDLDWSSKKEMTKSWQLDHAKENQIVMSPRSGCSDQPAVWSSSEQLSCCSEGVSKCSSDFENFCEQICNLPELKRVSFCSSELGGQEASKGASHDTSSAGEHEEELADEMCIDTVFTRDFYRLVKFESNRSLAASSKSLATSDGLLTIERLQDLESSGSRKEALASVLGFIAEQQKYCKEREAQDEKVGSSHSRDMLKIANAIECAGSPLASVLFRGTFPKSALREGTGDQKKASEDFSMRTLPTKSWKQSNSVKSKVGPAVPAKPRSCYLQGGQPGAATSNVLPTTPARCHPAAASSSLPAASAELPPASLPVLPATSHPHPSVPSRSSSLAPLQAIPACEEEVPLSPIPTVPIRNASHPPDTDSIPEQQIYCTPCPEVPHHNPPVPDHNCVDMSCFPPVPRRSSSMAFCCNVLPVPEHKVSLNDPPPVPKRITSRALPKPPPVITSQASLNNANGTSKSSGHEGKRPRSFLGLGISSPKRPQSEHHELPSLSENPAGMLVELQRMAKVEEEEEEKRQRPRPGGLYEATSPGGSVGLGTGWVRVQPHVDLQDPQARANLLDGMMESSEGCSSETEDDEGMAHQYAQLRSMHRSRRKRKGLGQGQWYDSPLIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBA7</accession>
    <name>A0A3R7QBA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003696">
        <property type="protein sequence ID" value="ROT62412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBA7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="574" mass="62908" checksum="2331DF69F96D5391" modified="2019-04-10" version="1">MLSTPIPTPSPPTLPTHTHSLSRPRHPPPPTHTLQQTTSSSPYPITSHSRPFNRPSHPPLPTSLFLPSPISRTRPPHTPSQTTSPSTPTPPAPHTTPSADHVTPSNPPPPHTHHLQIPRHLPQSPLQADHVTPQPPHTPLQHTTSPLPPPLHTQTPSADHPTPNSPPPLPIQDSTPRVTSSFLFLPRFIQLPFIPSSPSSLPRIQFLSSPTQHPSPSPPPTSQFIFLSLPLSPSPLSISCTHYMFVPLSLSFIIFSSVSFSFSRSLFLLRSLSNHLFIRFVLSPSFFLSQYHYFILSLSPSLIIPSLSIQLLLMVFVSSPRSLSNCPLRYLLLSPSRCSSSSSLFLSLFLHLSPSLSFCFFSPPYSVLILSLSLSFSSSLFIRFFFSLFASPPPRPLSNDPFLYLLLSSSSSQPPPPPSPTNPHYQHPPHPCPFPYHPHYQYPNPSLPIPTNPTLPAIPFPTNPPLLAPPPSPLPHSYNPPLPASHVPPSLPHPPFTSATPTPPPWPRPLPTPLPLSPHPHSHYPTLVINDHTPSSSWPYTRPRFPTPSVSFASPSALPAPNSPYAVPSRLSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QDK6</accession>
    <name>A0A3R7QDK6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017909</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003311">
        <property type="protein sequence ID" value="ROT64162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QDK6"/>
    <dbReference type="STRING" id="6689.A0A3R7QDK6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="41223" checksum="0BCFFA2BF157966B" modified="2019-04-10" version="1">MKQGITVNNNNNKIYSPFTPLPPPSLPQNPLSLLFLPQIPLPPLFLRTLPSSFPSSANSFLFLSLTRPRFFPQYILHPPLPASSSPISTPPSLPPPPSPLSHPVPLHFSLKIHFLSPSFFPCLITSPSSFPSSISPSMPTSSSLLHTSPPFFSLLTFFLPPSFLPQSTLLPPSFKPFSLHFSPITHFLLLPYSAHIFLIPTTFFPPSHFLPQSPPSTSLLHTPSSNLCHFTSGLPVPPFFPTSSSPLHLPFPHFSLKSPSLLLLPFLPLPPFTHIPTPTPFLQTLSLLPSPLRSSSPTPPSASTPPHPATPASKTSSFTRARPSPFFFKDIFPFVSAPSPFYSPLFRTPSSPPPLFPSFDFYPSPPFADSLSYPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFL4</accession>
    <name>A0A3R7QFL4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger FYVE domain-containing protein 26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004096</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001545">
        <property type="protein sequence ID" value="ROT77276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QFL4"/>
    <dbReference type="OrthoDB" id="1936617at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032465">
        <property type="term" value="P:regulation of cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057946">
        <property type="entry name" value="TPR_ZFYVE26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028730">
        <property type="entry name" value="ZFYVE26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46591">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46591:SF1">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25569">
        <property type="entry name" value="TPR_ZFYVE26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="8">
        <location>
            <begin position="2209"/>
            <end position="2269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="548"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="633"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="824"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="548"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="652"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="684"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="824"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT77276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3019" mass="336726" checksum="95B3F2D96EB09550" modified="2019-04-10" version="1">MKDTAGGSGPLLRFLFQYEDRIQKEIFSIFNQEDTDTTKSHVSLSDEARTALRDKLLSHPHETSCILHELVVRSRTLRDRGGDQENVSEAENKNVKSEEKGSLELIKKKGHCIFGDILKECLDHCLRRVESLDDKLKGMEEDYASAINRPKKNFSPKKLSFGIPKNGSSESVEVVKLLERSQATEVEKQRNEVLLYKILSLSSDAPLSYLCELFPRMLRLCYEKNLLVSNKLHFTNLSSSDTCLRLFCEMEGEYLSSSSRINKASLVERLPSFAPTDIREMFLSCAADSKHVLQLVFEGLVVDGVKSMKEMEGCDTENWILTLWPMIFLHAWSTSVDKMESLIWISAVWENHPKNIDPLLFDICSDLNRDMDLVRWCLTRSSSVKILPLLQLIRNHSPLFTLHKSLPLHTLWPEEVLHLLDEHSKARDPSGTLSSSCQSTYKAFCILLSVFQVIGSGMQLDNAVAGRQARGKLLGDKGQIFGRSTDMSSEGISNYRDRQAPLQFYQQNILEKLQDVRRMIDELKPLECRVEVMENIFSLLFVRHSDMSDEGQSESGGEEGELERSFLSQQTDVESLASTSHAFIDMHLNSATSAGDKEKEQSTKKVKVLDFADQVVLEESSSETVNLSVRELSPFGSASEEEKTSGSSTEANSKELKTTESSEASKIRGSSWPPASSERLTWDAHQQSPQSGPTFHHQSSCTVSGKSTGSSMGELPHTGYLINSLVAWDILLLLRDSILTASAQTYTEIGQQAESKESCSRKEVQVRLSSLSRLISEGLWRMQVIAPYNRKFGSVENFDDFLDGTLISGNTGYTVYENSIQTSAKSRVHNSGQTSNSQGMKKRHGKEHESPELSAGLQDHTSVITYLLAPPSSLITLALANGNVTRAEQVVKMYKVGDSTEKREVCLTNRLSQLRPKLSLTSQKSGKLKDSKGVQHKGYSKDLIQNIGLLAREGSAQVSTTNLIHDLVTSTPPPIPQCLSTKVIEGSCQIASSFLSPQALVLADLALTVDLTETTASYLMEQALQRSVSQPSVSSSLPKTIGSIQGYIPVLQKLASMCSTLIAVRTLECESDSDGANKNSSVDTFAYVCPFSATPMSLMLSPLPLGESELKNYVKAWSRFLDSFAETQDALLWCGDSDSVDSSINIHINSGKNRAHVSYKLLLQILSEKANHLYRSSIKECQDTKMGAFVRTFYQYLQLMSAMVTLHADEKYHNNMKSYFSLLKQRPVHILGSLMFQEGIDPVKLEPIAARMRLNLTAMILQYCCPKITVSYDFLHRGEHDTEVQDAASRLGSQVSQGQVILNSGTVAGTSAVYGEVIVRDILTSLLSGLKEAIQAQALTFTHCHKAVILNDATAPNALLSTDVQEALKDTAELAAIDFTKISPNEEAVVFFVNLANLMYIHAGLLNHILYPKSKSGESRGIFSCYLIERLMAMKHLGYNLGQLGFLSLYDVLFGVLQLQNPLSSLLIQNEVNVRVSLFESNLIKSSLQHENAEKLKHISGLITAIPSKLSFCITQGNPVSPLVQVIYADRLEEHIEAAVSEHLNMFSVLKESHSGDAEGQVDPPPGTQKVNVCVSRTILNYVAKHCNGTFDGIHSLMQEVNEELASVFNKSNTGISSKKQVEISVLDNGENQGIAVEYVEDLVNQEFAMTHNSAETNVSAAVSDGLDWTSVKVPPTVLSHLRRQCPLLAFIVQALHSTLEMKRQKGHSWADDETDAWHKILYPPDRGVKPQHEEVHHFQACRNVFTNSRYKALGRISQDSNVLSALLIDPDISSIWSLADQLLGSQTITKDCAMEQQSNVTSMMTVLQALPTATMEAHPNLQSLLDQLLVFILQTSDVSADPKPWMYAYHISDCNVRYTAIQEAHKSWPASAAVNHLNIMVYDTRLPRPKQEWAQNKAVQIGVYEEILRVGNPEVSSWQEVEKMSEEEPAVLLQMLLQKKQFKLGVQWAEHHNVSPELRRLVDQSYLMSVLDKTSPDYGTALEALHALSSDDLVIVTQALLERLSSPPTRRFLIEFLLKTQFLSEAVTLCKDNDELSRKEDGEGITHSAVSPSIALPNISDLQQEVMGLILVEDIAPHADDRFQLSHLASTPHLIIEQWLMNIKLEAVEKAIKTLSQHLDMVDSRMSSSIHSQDFGISSLCKEAGVQKREPQSLSWDVLNWLLEAYAAKALDTTGVQVTLKPQTLNENVPKKFVMPARPPERHEWIPDAEVRECPVCRVAVFSMFCRRHHCRRCGRVVCGSCSKARIVVQGYGDLQVRVCLECYQQTKNLNLEDYIQVRPLGDGTYDTVSQNSEGLVSARGGGGSSCTSDTEGGWYLSTDPDHNALVRQEFCYDYAPSLSLCLAILAQHQDHKRAAVCIVKLCHHLFSLIVSSIKSASPEVDNTFVLSMIQTLLASSKVRFGNIGEHQGIALCEYYTQWVDLISLLSKANCGYIIPIPSLQNMLQIGELHRKNLMGEEKLKEKLERCLQQEFVHMRHLRDMLVKKQLWELALNISTKAGLEATGVWGAWAMASLKAGDFPGARERFSRVLERPFDKRRPCRSSLLPEVIKYLESNPFSVDQKVMEQAERARANIMMNDQSRLPPSQALVVLHSLQELNGISNGLLTNKESNKQIFSSHRTKKKNNSKMDSLFQTECKYYLCLYGNHCMTIQYFMRNKQLQECVNYLLSEEIEVDLFVHEVLVPILRCGQLDMLLRNFRAIDPKQEKWAKYMLGGCRWLERQGWWNSLLAVQEALGDRLRAAMTLLRMYSHAVDSYNGLANRVHHLLAAKSHLQAYLDTQALNQSNAKKKKIILNMSGWQVNQHINTLTLQADVTKFLANCEAKGNVLCSLLHNLHKMKVLGNISLPTLLGDEEERLAVASLAICSAQSVADGLSLAYRVVEGSGISTEKLLSVVSQLLVAHEQYSTVGQVVRGMQEWGVLKAKTIDIALQPALLATASSTQNTHLDALVKLLSSDSAKIEAYIKCGRLKSAYLVAVHRGRHEDVVKVQEVAKSNGQAHVATMCSKWLANYENRVSARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QN85</accession>
    <name>A0A3R7QN85_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022326</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000534">
        <property type="protein sequence ID" value="ROT84476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QN85"/>
    <dbReference type="STRING" id="6689.A0A3R7QN85"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="210"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="156"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="292" mass="32946" checksum="7A4A5A40653C085F" modified="2019-04-10" version="1">MPAAEDTVKSSWADEVEEVEGGNLPPPVEKNDGTSKTITEYSMNDEGKKVKIISYYRIEKHRVARTIAERKTWRKYGLSKNDKPGPNPATTITAEDVFMHFLSNKDEEQNEQEEIKKKLLDQQKGQVKCRLCKEDHWTKQCPYKDKLEPLRSSLLGEEAAEEETPAQATPAEKPKIGGVTQGKYIPPSMRDGGSKKGESMMSSRGRDETATVRVTNLSENTREQDLQDLFRPFGDISRIFLAKDKNTGQSKGFAFINFKRREDAAKAIQVLNGYGYDHLILSVEWAKPSGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNM1</accession>
    <name>A0A3R7QNM1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000477">
        <property type="protein sequence ID" value="ROT84892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNM1"/>
    <dbReference type="OrthoDB" id="6512771at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="617"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="729"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="730"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="789"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="852"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="988"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="996"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1070" mass="123438" checksum="A76DA35A7CE73479" modified="2019-04-10" version="1">MPMVRPAGPPEPRNHARVVRTESLKSERSDKRVSFNKDVGVKHIPRGQKQQQIKNNLVRAPQEDEWAHCAAVHREPVNLSSRELEQQAEDLVKLLDHVNCDTAGAALAHNTRSLDRPKHKNNKNFAHHHYNNVIVNNVRNNAGPKNTNVLNGEPRGRPRTLPPARTANPINRRVKGDVNRAAHPSPSPLPNGGPLAHRHRSADHLPDSDLDSPPLARRPHPLAGHKSVPDLNAVYYDNNEAQSYKYQHLAGRDPDPRIGYKSIDALYERDEHGAKLNRAQSAGYKSVDNLTEHSQVGGGRLQGFKSVGHLPSTTLSDSDDADMSRPKPYKNKVGNIIKKFNAESDGTRHSNVLLETEMDVSPRGTLEPDRFRNHNNNQPFSYTGSLPMATVQTVRRLSPTRDLPPRASPPRDSPPRDAPVYAQVNKKDARDAERNYRNARQEREYSAKIIITDDDHRPFQDPYDDHFRDAKNHYQEDDDAYESYQVPEDNIKRLLHEDIMPARMLSSEDLLEEYKEQSNNNINMSSVGVQTDALPKAPSRSRKTHKSSSPSPTRQHQSQQKQYQVKTQHIKNEQKHHQNYHYEREPDHYPSSKHHQRGGNIHNNLTSATLVRQVNHGFGRTDRSPSPPLRRPQTRQPRRNVVPLLSDTSDSEAEHRRRTVDPLARIRDQVMQREKLQEEEEEEEEARNGRIGIKESGVIPYRPEEMMPLTIDEVDALSLVMEDTGKKSLVVSNQSQSTSVTRTTNHRSRRSETVTERVHSQPHKDSLPRPQKPPREKNHAIREATPTRGHREQTPTRGHRETTPTRGHREPTPTRGHRETTPTRGHRETTPTRGHREGTPTRLPREATPTRGHRETTPTRAHREGTSSRPREQRKDPPTMERNRKNNLEKERAAKASKQKEEKKEKKKKRIKIKFFYDPRPQDEPDVDPLAKFTEFRGSSSEDRPSPRDERRPDDAKDEFRHERTQRDEYHRSEQKEVREDSRPRRGLPDVLEDTTSLRDRRGSREQLNRSREQLSKSREQLARSRERLDRSREHLDRSRERLDTTPRQVRHSSRDVRETKTREVSESQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWL7</accession>
    <name>A0A3R7QWL7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001057">
        <property type="protein sequence ID" value="ROT80857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWL7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="58857" checksum="8C7C0F1853F724E5" modified="2019-04-10" version="1">MVPKGEEDGAKRERKKRKDEEDSVRQCQCHRRGRQCHKDSVTQTRKTVSQRRGRQCHKTRRQCSVTKTDSVTQTRKTVSQRRGRQCHKDEEDSVTKTRKTVSQRRGRQCRRGRQCHKDEEDSADEEDSVTQTRKTVSHEEDSDRQKTTRKTVSHRRERQCHTDEKDSVTQTRKTVSQRRGRQCHKEEEDSEDEENVTQTRKQCHTDEERQCHKDEEDSSHRQDSVTQTRKTVSQDEEDSVTKTKEDSVTKTRKTVSQRRGRQCHKDEEDSVTQTRKTVSQRRGRQCHTDTVHTDEERQCHTRKTVTKTRKTVSQDEKTVSKDRKTVSQRQEDSVTKRRGRQCREDSVRKTCDSETKDSVTKTRRQCHKDGRQCHTDEKDSVTQTRKTVSHRRGRQCHTDEEDSVTQTRKTVSQRRGRQCHTDEGAVSTKTRKTVSQRRGRQCHKDEEDSVTKSKKTVSHRRGRQCHKDASSSRDPKSRRGSEEEVAATIKVRSESHETDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QX78</accession>
    <name>A0A3R7QX78_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000965">
        <property type="protein sequence ID" value="ROT81509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QX78"/>
    <dbReference type="OrthoDB" id="8122776at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="237" mass="25725" checksum="4FD6634AC1A6B028" modified="2019-04-10" version="1">MQWWQPLAASGNSSGKLFSAVDMPVKVETAPRTFSFAAHIHPRANHSLANHISMVLTMVGVLALADKPPTGPQVHHFTGQPGFDSFGKSVASQPIYGGPSHDIGVAHHPVSYGHAPSHGYGAPAPAVGYQTAYIAYEPPQPAPQYYVKVKSNPLKDLDKKIKDYASKFTKFMSDYMDLNTYEEESYDPVYVAPAQSYGPPPTSYGAPPRPTALPPTPTALPSRPTRLSLSTRRRRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SXI4</accession>
    <name>A0A3R7SXI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001161">
        <property type="protein sequence ID" value="ROT80068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SXI4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="442" mass="48239" checksum="923711E4EB5303C7" modified="2019-04-10" version="1">MAFESKCQVSASTKDGTLGLVFQRLVKGDGTFPFPYPPPPLLFSLSPYSFPPPRPPTPPYLLPSFPLSSSTSSPFPPYLAHSPRPPILSPFLYPLLLVLFSLPSPSSAPSFPPSSCFLLSILTSPSSLSPSSPSFPSNLSFLPVYIFYSFPLRFSLLSPLPSLCFPLPSFPLSLTLLFSPFPRFPLPFVLSVLPGPFPLSFLFVLPFYLLLPHTLSFHLVLTPFARSFLPSLFPPFSLPCSSSNLPSPSLPFFPSPSVIFFSPFPPRSPSLLATCPALPLFVTSLLLPLSLPFSVPSPNALPPSPTFFLLLSPSYINFPPLPIALPFFSFPSLCPHGSFPFIPSLFLRFLSSLSPTPFLFVIPSLHSTSFLPFSPFSHFPFLFALSSLPFPISSLTLPFHPPSLLPPLPLPPTRPPFSFPPLPSHSLSPFLPPLTNEAERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZB6</accession>
    <name>A0A3R7SZB6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">N-terminal E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="2">2.3.2.23</ecNumber>
            <ecNumber evidence="6">2.3.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024037</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="2.3.2.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [acceptor protein]-N-terminal-amino acid = [E1 ubiquitin-activating enzyme]-L-cysteine + N-terminal-ubiquitinyl-[acceptor protein].</text>
            <dbReference type="EC" id="2.3.2.25"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="2"/>
    <dbReference type="EC" id="2.3.2.25" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01000775">
        <property type="protein sequence ID" value="ROT82793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZB6"/>
    <dbReference type="STRING" id="6689.A0A3R7SZB6"/>
    <dbReference type="OrthoDB" id="406833at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23808">
        <property type="entry name" value="UBCc_UBE2W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000022">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="21"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="169" mass="19170" checksum="BC704B1D2A9868D5" modified="2019-04-10" version="1">MYLFVVEFPTPSVPLRGPCLPQQKRLQKELMSLLKEPPAGVTVDVDTAHTKLTEWVVHMEGAAGTLYEGEKFQLQFKFSPKYPFDSPEVIFVGDNIPVHPHIYSNGHICLSILTEDWSPALSVQAICLSIISMLSSCKEKKRPPDNSYYVKTCSANPKKTKWWYHDDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-03-27" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T1J4</accession>
    <name>A0A3R7T1J4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000222">
        <property type="protein sequence ID" value="ROT85660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T1J4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018602342" evidence="1">
        <location>
            <begin position="19"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="684" mass="72373" checksum="5DFAE0195B09DEB5" modified="2019-04-10" version="1" fragment="single">PFIPVLLLPALVSTPSLSVSPPHSGPSLPPPPLPLRLVPSFSHIHLFLSLIFLSSALPPLDMVVEAERTGSSLLVSLPSPLLSSSPRSFPPRLSSLAQFSLSLSLSPPSLPPSSSLPHFSAHLFSASLFLRSIASPSPSPPPPLSSLCLSLPSFFSLPPHLSPPSDLSLLSSPGLPLVLLSLLVPYPFPLCHASLPCSRFFLLSLSLSLDPSVHPLFPTNLSLLSPLSLSIVSRSFSRSSSSLLLSLDSLPSRSSFSSPALASSLSCHLSLFSLSIESSLLCSSSSLPPQSTLPHTSPSFRLSHLSRLSLSRSLLDSSSPSPSLPPPFSPSSFPSNLPSASLLPPFPHLSLSIFPPSTSSFPLLDLPSPLSLSLLFVPLSVLSLYSLRLYLISLIVPLSISRLSPSSYLPLLSSPPSRPSNPLPPPWSLSLAAPVPPVPSTPLSPIGDIIMFLAPRVSKCLSLLPVLLRSPLVTSLPEGDPFWFSLSLSFAFLPTSLRVLISSISPPLLLPFIALPSSHSCIFLPPFLHISSYLLPPLAMSFLAPSVSFLSRSPYPHLSLSPPSLPPSSLSTWLPSPLSIFPSLPSAPSICNLSLFASLARCLSLPPPLSFTTVLSLLRCAELILFRIKEDFVSPCNSSCKVVDLTLPSLEDGNTNPLTSLKGSLPPTPAVLNGDNRLGNIALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9F2</accession>
    <name>A0A423S9F2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative RNA-binding protein 39 isoform X7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_021484</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004511">
        <property type="protein sequence ID" value="ROT60862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9F2"/>
    <dbReference type="STRING" id="6689.A0A423S9F2"/>
    <dbReference type="OrthoDB" id="8123449at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12284">
        <property type="entry name" value="RRM2_RBM23_RBM39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000080">
        <property type="entry name" value="RNA-binding protein 39 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000090">
        <property type="entry name" value="RNA-binding protein 39 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="175"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="273"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT60862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="56311" checksum="86A62FDC808B9D4D" modified="2019-05-08" version="1">MRGCSVLFSPPSLPFSHHQPWLVLPLHRLLCSPRTEAVRRRTPNPRKMVTHPQKTRASPATGGRKRVANPETEIERSLGPGLGTRTGGKGLDQDQKIGNEDHALAAVAKVAAGIGAVVGVVAGTGAAVKVVVENAGGEAAVETGGGAAVESVDVHALGVKHQNCKELSVEERDARTVFCMQLSSRIRSRDLEDFFSVVGKVNDVRIITDAKTRRSKGIAYVEFVDVESVPLALGLSGQKILGVPIVCQPTQAEKNRAANTAAVQDQKAATGPMRLYVGSLHFNITEDMLRGIFEPFGKIDHIQLIMDSETGRSKGYGFITFHNSDDAKKALEQLNGFELAGRPMKVNHVTERSETQQGTSLLDSDEMERAGIDLGATGRLQLMAKLAEGTGLQLPAAAANALHMPAQPQQQPAPPIATQCFLLSNMFDPSTETNPNWADEIRDDVLEECNKHGGVLHVFVDRQSAQGNVYVKCPTIATAAASVNALHGRWFAGKMITAAYVPVMSYHSLFPEAMNATQLIYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAB5</accession>
    <name>A0A423SAB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative E3 ubiquitin-protein ligase SHPRH-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_021110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004331">
        <property type="protein sequence ID" value="ROT61154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SAB5"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18070">
        <property type="entry name" value="DEXQc_SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15547">
        <property type="entry name" value="PHD_SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16569">
        <property type="entry name" value="RING-HC_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000013">
        <property type="entry name" value="E3 ubiquitin-protein ligase SHPRH isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048686">
        <property type="entry name" value="SHPRH_helical_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048695">
        <property type="entry name" value="SHPRH_helical_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21325">
        <property type="entry name" value="SHPRH_helical-1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21324">
        <property type="entry name" value="SHPRH_helical-2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="1029"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1110"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1282"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1358"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1417"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1282"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT61154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1448" mass="165392" checksum="6AC2C017F4385F82" modified="2019-05-08" version="1">MKLKHDTEVLYKAVKEYHNNIEYVDLDVQHSSLIPQLRPYQKAAVRWMLHQENYGGDKQKDEWELHCLFTEIKCEDGTELYYNRYGGFIVKDKPLAVAPSPGGILADEMGLGKTVEVLSCILNHPRKEVPKPEYQEPVRVEQSRKRKSAKKDVAGDVYTLHQEENEDEDNAIDSKSHIELSCNKSPSEEKEETPAKRGKGRAARKQQEISEDTHWSSIESVIINECWEGKAKEYKKEGSYKDFRKYLKMKKKDPYHMMSLKERLQAQYKNSIAEYSAVGFVSKRAIQGFFDLKVEQKSYFECICGSTTAENRDEKFRVQCSVCSLWQHAECVQFDVSDPYRGVYICPHCWTQETPVVSEATLIVTPSSISYQWVDEIMKHLKNKALRMLVYKGVATQGYMQPRFLGNFDIVITTYETLRQELNYVDLPHSNSEMGRRCEPFRHPKRFMATPSPLPCVEWWRVCLDEAQMVECTTTKTAEMALRLAAINRWCVTGTPVQKSVNDLQGLLMFLGVDPYGVAQWWHRCLYVPYCHHQKEPLHNLVSQYLWRNAKKDVIHQIDIPKQMEEIHWLTFTRVEEHFYQRLHAECSYDAQQRLKKFSDPKTKLSDLDRQTLSSLLHPLLKLRQACNHPQVVKGQFMSINRKTMTMEMLLDNLIKKTKLESEEAHRLLVASMNGLAGVHIIKEEWVEAVNVYRGVLQSIEEHSNIKTDSLQRLHTLHNLAELIESNHQGVAPTLRDSTLREQAEAIRKRYLQHHPQQVTAANEECTSNTEAVDELKSQYNSRIDWWLGALQSFDNDFVQELTSMLDLAIDCHLRPTELEPPQCLLCATHEFFEDYEETLFSMKELKHSRTTGVSKETEDVKDKAQVLQATRRGNWGQSETERVLRYLQTRCLGKVENEIYEDSHVYFQSLEAMKKEFKNYRILWRSLFDSVSAMDEVNMATIRLRLRFPDEELPQQKKKKNGPDLDKKVEALRYVIEPAELDQQEIKLKSDQIVAKNDLRIKLGQLLYLQNLSKTDFGKEGGKNPEPCPICQGDLGEKWAVLLCGHCYCMECMRTLSNRGFNGLDKSNVKCPMCRQPTRTREISYVDTKAKEEEEYIKVQGSLSTKVEGVVRLMLKIKLSDPEAKVLVFSSWVDVLDVIADAFAQNGITFRALHQHSKFQKHLASFKSNSLISALLLPISSGANGLNIIEAAHVILVEPILNPAAELQAIGRIHRIGQTKETTVHRFLVRDTIEDRMHHILKHHHAIIHTDENTVTIEDLRNLFLHPEELELQREIALGTSQHNGTDSPQCDSQPQEGSGEGSGCRTSSGSTAASVANGSVLSALESSDSVSSPSTSKQSVSHCNSDYVTVVKASSSWLQPDEDQPSTSGHSADELSCDRNLNPDSPASEFFMCEAPERNSLQSSCTHEVDSAVLPLDSAPQEIDMSPAAPRDNTVPLSPSSSLHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCG9</accession>
    <name>A0A423SCG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003941">
        <property type="protein sequence ID" value="ROT61901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCG9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050972">
        <property type="entry name" value="SDr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34403">
        <property type="entry name" value="TOL-PAL SYSTEM PROTEIN TOLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34403:SF8">
        <property type="entry name" value="TOL-PAL SYSTEM PROTEIN TOLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="37672" checksum="81DDC215754E040D" modified="2019-05-08" version="1">MKQVQRLALKQALKQAGTESSTEASAKAGTEAGIEASAKAGTEAGIEASAKAGTEAGIEASAKAGTETGIEASAKAGTEAGNEASAKAGTEAGIEASIEASAKAGTEAGTEAGIEASAKAGTEAGNEASARLAKAGTEAGIEASAKAGTEAGNEASAKAGTEAGTEASAKAGTEAGIEASAKAGTEAGNEASAKAGTEAGIEASAKAGTEAGIEASAKAGTEAGIEASAKAGTEAGIEANAKAGTEAGIEASAKAGTEAGIEASAKAGTEAGNKQVQRLALKQALKQVQSGTEAGIEASAKAGTEAGNEASAKAALKQAEASAKAGTEAALKQVQRQELKQAMQVQRLALKQALKQVQRLALKQALKQVQRQALKQALKQTKLYSLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCM7</accession>
    <name>A0A423SCM7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein lin-10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003896">
        <property type="protein sequence ID" value="ROT61977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCM7"/>
    <dbReference type="STRING" id="6689.A0A423SCM7"/>
    <dbReference type="OrthoDB" id="5987010at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043197">
        <property type="term" value="C:dendritic spine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06720">
        <property type="entry name" value="PDZ1_APBA1_3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06793">
        <property type="entry name" value="PDZ2_APBA1_3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01208">
        <property type="entry name" value="PTB_X11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000007">
        <property type="entry name" value="Amyloid beta A4 protein-binding family A member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000017">
        <property type="entry name" value="Amyloid beta A4 protein-binding family A member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000207">
        <property type="entry name" value="Protein CBR-LIN-10, isoform a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051230">
        <property type="entry name" value="APP-Binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12345">
        <property type="entry name" value="SYNTENIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12345:SF16">
        <property type="entry name" value="X11L, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00640">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01179">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PID" evidence="4">
        <location>
            <begin position="11"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="191"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="282"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="40945" checksum="3267984E7D0C2868" modified="2019-05-08" version="1">MIHEPAVLIEGVLFRARYLGSTQLVSEGQPTKTTRMMQAEEAVSRIKAPDGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRVLPTDDTGNNIQKTPKMICHVFESDEAQFIAQSIGQAFQVAYLEFLKANGIEDHSFVKEMDYQEVLNSQEIFGDELQMFAKKELQKEVVVPKMKSEILGVVVVESGWGSMVPTVVIANLSPTGAAAKCGQLNIGDQIIAINGVSLVGLPLSTCQNYIKNTKYNTAVKLTVVPCPPVVEVKIRRPDTKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIDINSQSVVAVPHEKIVNLLATSVGEIRMKTMPTSIFRLLTGQETPQYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEG4</accession>
    <name>A0A423SEG4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003621">
        <property type="protein sequence ID" value="ROT62586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEG4"/>
    <dbReference type="OrthoDB" id="6379939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301:SF12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="644" mass="73318" checksum="89648415BD8E8F00" modified="2019-05-08" version="1">MVNREEESEDFHLPTPPEMSSAESSTEECIQNPERGETPVTGPWRVAEEAPPPPEDVNNLTWEHFPVIEDSPEEPQTPEEEVQEPSILSIGPHEITYKRKTTQDAEDTDTHSPLMKEVNACQHLIERVIGAIERMENIVARQDEQLTARSQGGQQLPQQSGTSQPHRSSWQGFQDHASQERRRKKRKPRKKQRKQQTQEDIRVQENAPQQREATSQPQRRRFRTQETTVEQRQDQRRNTWNPPQHHPQRNARVNRGRGTQQTPPQDFQRRPYPTKVSEGESGTPAIRGTHTGGRDRGTPTRKEDTTWETDTMVGQTIKEETPSGEQEEEKEDSGKKKIQTIGHGIGGQRDALLEHKPSIPHWYVLPKTHKPLDHVTGAWPGRPVLSGCSSPTRPVDRLLTTYLTPLLDLLPERLQDTTSFLQKMRDAKRYPGAILFSFDIVSLYPSIPQEEAAYVVANFYEQNFSYVEERLFSDFNMAAPPPYLIKEGIDHVLGGTLLRFNNRFFRQGKGTAIGASVSVAALRIKRIVSEEHKLETALQEMTGFFKARGYDNRCLNSALERVGNLQRDQLLIRKGHTLGNSLQDPPTNDSMEERKIDCREADQSAVPVASGRAQGVNEWQTTRLRYLKENRGGPRLPQSSKPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGG6</accession>
    <name>A0A423SGG6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Metalloendopeptidase</fullName>
            <ecNumber evidence="10">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_018815</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01003452">
        <property type="protein sequence ID" value="ROT63306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGG6"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9 10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018807792" description="Metalloendopeptidase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="13">
        <location>
            <begin position="130"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="12">
        <location>
            <begin position="367"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="12">
        <location>
            <begin position="667"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="491"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="502"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="174"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT63306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="783" mass="87600" checksum="406F2F3A0B74062F" modified="2019-05-08" version="1">MAFEKTSLCLLLIPCLTLTQIIREEATPDHNIYYESEENTEEPHFVLSHRSNEEVTPDNQIYYEEEQANTEPHFILDRNMDDRANTPKEGFIILPRPFEETNPDRVEAGELFDKDMLLTEAQWRDLALRKGLASQNYRWPEKDGFPYVPYRFIDSEVDQEAVMAGIAHWEQRTCIRFGLTTNFNQPHLKFQKGSGCWSYVGYISASTTGQDISIGFGCTSLGIVAHEIGHAIGFYHEQSRPDRDDSIHINEENIVDGRENNFAKISDSFVDSQGIPYDYSSDMHYSGFDFSKNGRLTIATVDPRNQELIGRRDGLSHRDTHLANLMYGCIDKWKQACGMDSDPCQNGGYTGVDCSCVCPQGTSGSSCETLEEDYFASQRSDCSARITSPGTVTSPNYPSNYPYGVVCAKWVVAPECKLPRVTFTAFRLSDCWDNLEIRTSNRYDGDFYCGTSIAPGTSFTSTTNELILMFYTRTNYETGWSADVTFIDDPNCSPATTQAPTTQPPTTQPPTTQPPTTQPPTTQPPTTQPPTTQPPTTQPPTTQPTTTSQPPPSCSLLSASVGVTWLSPYFGNDNYPNNFKCGIRGSTSSPYMATFKMNSFQLQKKKRRQCLDYVGIQIPYNRTVKLCGKRRGAVLVPVLNLRANFVTDNAITDAGFNFSITWEKTGCHQVIELSDDSATGVIQSPRFPKKYPKNSVCEWWIVAPEGKRIQLEFTQISIRDKKCLNAYIAVDRSGKASYLRDDSSLLCAAHKSADVLSDGNTVNVAFAGGRRRSRGFSARYTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH45</accession>
    <name>A0A423SH45_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003430">
        <property type="protein sequence ID" value="ROT63505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH45"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="40291" checksum="D709C5434F68EFDB" modified="2019-05-08" version="1">MREKKKLKSKFCSLVILAPHRCFTPVAALLPLPLYSLPACRRAVSPLTPLLPSPSSRIALTRAGQEHGPAPMTPPLFHSLPTDFPLPSSPFCHSLISIVSPFSIPYRCSARFSALPALSCLSLSRPPPIPPLLSAPFLPLLSLPPKALLISLPPLSLLSPPNLPAPFSPCCSPCHCVSLPCACSCPWFCSPGRGALASRSLWPSRFLPLPPLLSLSSLLRWSPSSLPPLLSTATLPSSLLSPKSRRPPTRLSSSSSYPPRHPLHSWSFSLPSTYPLPLPLPSPPSLLLLVGFLGLSAPAVCPLPPLLCLLLPCTSFLPSPTSNSALLPSLPFSPSTLRPPPTLPALPLLRLPCCPSLPPSSTYPLPPPSLLPLPSPLSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHS2</accession>
    <name>A0A423SHS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nesprin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003388">
        <property type="protein sequence ID" value="ROT63732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHS2"/>
    <dbReference type="STRING" id="6689.A0A423SHS2"/>
    <dbReference type="OrthoDB" id="18740at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034993">
        <property type="term" value="C:meiotic nuclear membrane microtubule tethering complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005640">
        <property type="term" value="C:nuclear outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21243">
        <property type="entry name" value="CH_SYNE1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000033">
        <property type="entry name" value="nesprin-1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047291">
        <property type="entry name" value="CH_SYNE1_rpt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052403">
        <property type="entry name" value="LINC-complex_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057057">
        <property type="entry name" value="Spectrin_SYNE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47535">
        <property type="entry name" value="MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47535:SF1">
        <property type="entry name" value="NESPRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25034">
        <property type="entry name" value="Spectrin_SYNE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="7">
        <location>
            <begin position="5"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="527"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="904" mass="104834" checksum="14E5817CE3DF7686" modified="2019-05-08" version="1">MTWKLGAKKALLEWVRQTVTKKFGIVVNDFGGSWRDGNAFLALIHCINPRLVNLQSMAHLSNKARLDAAFRLAEKGLGIPRLLDSEDVDVDKPDEKSLMTYVASFLHKFPEPGVTHECTSPTLEATTGDDMFSEIEMEYTELTTWLCHTSNWLDTLHDPDTHGNINYERFKALKSEADEKQVIYEKLAGLMDSQSSMISITSDSWQDIIASWNKIANLLSKKIEEHKAFFAELPSIVTKFESLKNSPDASVIPPQQLEYMELRLKTIAPRAAVRKIKLKYLEHRYCLVAFLILVEAKLKTWAVKYGREQEVQQILSEYRSFVGTRNIFQEFDRAFLEMQQVAEAYKKDSNLSKAESDGIAKFLLEMNERWKNVSVELRCIQSLLEEVITYWQKFVDLTEQFEVWLERALSMVGLPEEEKMEFFQDLGEWRDKHTQMNETGNFLAATCRPEVAQEIREKLITINAKWDELFQGLFNGESMSTWEYVQQYLHRGQILRTKNDYRSGQDRLELWLESAEVTLNTTNVCTVEAVKEYAEELKKLNTEVEEMEVLFKNISKSFQALVQELTPDEIERMMWSLKQEKEELVRIRTAIPQKTYLATQIITQLEAVDSGVKEINKWLDEGDALLASFSLHGTNENIQGQLDKQKTEDQLYCFTYTGTNETTRQQLEMHRAFFSRQLYYKSMLDTKNRVYQNLLRTTNGGENLDVQELQDTMNQLNARFTEVTSASVTWETRMSESIRCWQSFKECESEITEWLTSAEKLFQEKAITTKSYLESHKKEHNTTTRLITNRFNLIHYTPSSPPLHHTATTHITFTILHHLLHFITHPSYSTTSSTSSHRNHTNHIHFTPPPPRLHHTAYTATILHHLIHFITHQNHSHPPSSTSLTTSTILHLITNHIHPTPPHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI67</accession>
    <name>A0A423SI67_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003364">
        <property type="protein sequence ID" value="ROT63843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI67"/>
    <dbReference type="STRING" id="6689.A0A423SI67"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="38175" checksum="AF5B89E66D36B013" modified="2019-05-08" version="1">MNAGINQGNISAELAKTWRRTVSEAKSSVLKTLSFAAFLTVVVAADPTAESRSRRRLYAGRPFPSASPSTGPQSCPAFGDGSRRGRGFLAAGGHARSAAPVREGAGGEAQPAGGPRTAAQGPARSRRRARRGLATRPPAAEGAPPIVVGAGPQPPRPRPGPALGRPPGKNGPSVGDPGRAAPVPYAAAHGPRGRRGRRGKAQPAPARGRRGRLTGSRGSPPVVVGAGPQPPRPRPGPALARPAGARPRRGCGRATPESHATALGPRGRQGPMGAERPRWAGRRAARPLRPGGGTGERTEGRRAAAAAATQQAKGGARLRRPALPARPAARPTAAPHPTASPIVGGAGPQPTRPETGPSIRPAGAEPGDARGDCPAGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK59</accession>
    <name>A0A423SK59_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferritin</fullName>
            <ecNumber evidence="6">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ferritin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01003221">
        <property type="protein sequence ID" value="ROT64628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK59"/>
    <dbReference type="SMR" id="A0A423SK59"/>
    <dbReference type="STRING" id="6689.A0A423SK59"/>
    <dbReference type="OrthoDB" id="186462at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01056">
        <property type="entry name" value="Euk_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.10:FF:000002">
        <property type="entry name" value="Ferritin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431:SF75">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 6" id="KW-0409">Iron storage</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="7">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601519-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="169" mass="19432" checksum="E47D859CD8DEFC83" modified="2019-05-08" version="1">MRQVRQNFHEDCEAAINKQINLKLHASYVFLSMSYHFERDDVALPGFAKFFKEAGDRERDHAHQLMNYQNKRGGGIVLQPIAAPPQQEWGCAVEVVQMALDLKKRINQSFLELHVLSSTKDDPFTCHFIDDHFLIEHVETIKKMGDMVTKLRRVGAAGLGVHLFDQELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKX3</accession>
    <name>A0A423SKX3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase MLL2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003171">
        <property type="protein sequence ID" value="ROT64897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKX3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="50292" checksum="7178AA2DCB134522" modified="2019-05-08" version="1">MWRPCVISTSSLKWKPPGGLRQSSPRKKTKRGTEVNRARAGDPGGGTRTGDPVGGTRTGDQEEEPELETQEEEPELETQEEEPELETQEEEPELETQEEETGDSGGGIRAGDPGGGIRAGDPGGGTITGDPGGGIRTGDPPNWEGRNPNWRPRRRNRTGDPRRRNLEGGGIRLETQEENPNWRQRRNPNWRPAGTGENWRRKESELETQEEGIRTGDPGGGKLETQEEEPELETQEEEPELETQEEEPELETQEEEDWRPRRRNPTGDPGGGTELDTPGGGIRTGDPGGGTRTGDHPGGESETGDPGGGIRTGDPGERNPNWRPRRGTRTADQGGGTRTGDPGREPELETQEEEPELRNPKRPRRRNPNSELETQEEEPELETQEEESELETQEEESELETQEEESELETQEEEPELETQEEEPEPEAQQEEPEPEAQQEEPEPEAQQEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMS9</accession>
    <name>A0A423SMS9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">tRNA-t(6)A37 methylthiotransferase</fullName>
            <ecNumber evidence="15">2.8.4.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_016476</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:37075"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="Rhea" id="RHEA-COMP:11092"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:74420"/>
            <dbReference type="EC" id="2.8.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="15">Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Endoplasmic reticulum membrane</location>
            <topology evidence="15">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the methylthiotransferase family. CDKAL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.5" evidence="15"/>
    <dbReference type="EMBL" id="QCYY01003075">
        <property type="protein sequence ID" value="ROT65547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMS9"/>
    <dbReference type="STRING" id="6689.A0A423SMS9"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035598">
        <property type="term" value="F:tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000005">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000002">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006466">
        <property type="entry name" value="MiaB-like_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01578">
        <property type="entry name" value="MiaB-like-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918">
        <property type="entry name" value="RADICAL SAM PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918:SF45">
        <property type="entry name" value="THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 15" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 15 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="17">
        <location>
            <begin position="54"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="190"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="16">
        <location>
            <begin position="420"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT65547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="564" mass="63735" checksum="18BC75F87A76A032" modified="2019-05-08" version="1">MEDIEDLVKDDGEVLVPRNRNAVMPRVRRRKGVLTNKENDEYEGECDSFIPGTQKVYLKTWGCAHNSSDSEYMAGQLAAYGFKIIEDKQSADVWVLNSCTVKSPAEDHFRNEIKAGREAGKKVVVAGCVPQGAPQSEFLQGLSVVGVQQIDRVVEVVEETLKGNSVRLMGQKKEHGKKQGGASLLLPKVRRNPLIEIISINTGCLNQCTYCKTKHARGQLGSYPIEEIVARAKQSFTEGVCEIWLTSEDTGAYGRDIGVTLPDLLWKLVEVIPEGCRLRLGMTNPPYILDHLEEIAKIMQHPRVYAFLHVPVQAASNGVLADMKREYTVEEFCRVVDFLKEKVPGITVATDIICGFPTQRKISQETIELCRRYKFPSLFINQFYPRPGTPAAKMQRIPTKEVKNRSRQLTELFQSYRPYDHKLGEKQTVLVTEEAHDKEHWVGHNKFYEQVLVPKHSDFMGKMVEVEIIETGKHYMKGRPCEASKPVSPAISEPLPKGKVSGLIENAKDTLDSTQRNQLKEDLAKQERYIILSFVLLISALLVKLAWDIWPPRRSPTGRGNWHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNR0</accession>
    <name>A0A423SNR0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">26S proteasome non-ATPase regulatory subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_016153</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003023">
        <property type="protein sequence ID" value="ROT65865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNR0"/>
    <dbReference type="STRING" id="6689.A0A423SNR0"/>
    <dbReference type="OrthoDB" id="261572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000017">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="799"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="8">
        <location>
            <begin position="816"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="869"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="965"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="870"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT65865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1000" mass="111973" checksum="63E66FEDE12CDCAE" modified="2019-05-08" version="1">MGFITSAAGILALLDENEDQLRVFALERLNEITDTFWPEIADSIQKIEKLEENGEFPKRELAALVVSKVYFHLGSYLDSLTYALRSGPMLHQDRNQLYIDTIKVYYLFSAYSSCIDHYIKLRAQKDAKMDARLEELLNNMFKRCITDQQYRHAIGIALETHRMDWFREAIMTSDDIVGSLTYSYKIAMQYIEQRKFRDEVLEELVSLYQGLETPDYVNMCQCLIHLDKPHEVASILDKLIKNDSLKSEAMDNELMAYQIGFDLYESATQDLLSHVRQGLRTTAPVPSLLKDVDAVTSTTSTSAAPAEGSTSGTNEDEEMATPQTEEENADTAMSEEKTLDDLTELEKTHQNRVANLARILSGEMTIEQHLQFLIANNHTDMLILRHTKEAVRASVCHTATVIANAFMHCGTTSDQFLRDNLEWLSRATNWAKMTATASLGVIHRGHEKEALTLMQAYLPKESNSPGYAESGSLYALGLIHANHGANIIEYLLNQTKDATSDIVRHGGCLGLGLAAMGTQRTDVYEQLKYSLFQDDAVTGEAAGLAMGLVMLGSANEQAVSDMVNYARDTQHEKILRGLAQGIALTMYGQQDQADRLITELSEDKDAILRRAAMYTVAMAYCGTASTPAMKRLLHVAVSDVDNDVRRAAVEALGFLLFRSPDQIPSMVSLLSESYNPHVRYGAAMALGVACSGTGQKESLGLLEPLTNDPVNFVRQGALIASALVLIQQTESTCPKVKDFRQLYAKVIGDKHEDSIAKFGAILAQGIIDAGGRNMTISLQSRTGHTSMTSVVGMFVFTQFWYWFPLAHFLSMAFTPTCLIGLNSELKMPKMQFLSNAKPSTYGYPAPLEEKKKEVAEKVTAVLSITAKAKKKDDERKKKEQKDEKMEVDEEKEKKEKEEKEKEEKEKEKKKEEEKKKEEPTFDLLSNPARVMKAQLKVMRMAEGSRYTPVKELNIGGIILMRDMKPEDSEELVQPVPALGPKTEEETEPDPPEPFRYVDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPN6</accession>
    <name>A0A423SPN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002985">
        <property type="protein sequence ID" value="ROT66162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPN6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1024"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1116" mass="126191" checksum="68535F2447FA91D1" modified="2019-05-08" version="1">MLFLLILSPPSGFFFQHSIPGGFLTHSRSSSRSILPHSIPSGSFPHPFQGSILCPTLQFQVNSFPQLHFKVDSSTLRSRSFLPTLHSSLIPSHTPFQVDPFHTPIPGSILSHTPFQVDSFPHSIQVDSFPTLPFQVDSFHKLHSRSIPFPTLQVPDRFFLHHSFPGRFFPTLSSIQVDSFHTPISRWIFFPVTPTPGRFLSAHPFGDSFPHSIPGRFFPTPSVPGDLSHTPFQVDSFPHSFQVDLSHTPFQWILSHTPFQDGFFPTLHSKVDFFHTRSFPHPFRIVLPHSHPRWILSTGFHSRWNSSPHSFGFLSHTPFQVDSFPTLPFQVDSFPHSIPGRGGFLPTLHSRWILSHTPFQVILSTSIQAFLHSPFQVDSFPHSIPGGFFPTSPFQVDFPIHSSDFPTLHSRSILSPHSSGSFPHFHPGRFLPHSIPVGSFSHTPFQVDSFPHSIPGRFFPTLHSSFPIYIISNTPFQVDSSHTPFQVDSFPQLHSRSYFFLPTLHSSDSFPQKVSFPHSAFQVESFPHSHFQVIIPTLPIPVDSFHTPFQDRFFPHFHSRWILSHTPFQVDSFPHSIPGGFFPTLHSRWILSHFPGRFLEWITHTPFQVDSFPTSIPGFFPNFPGRVDSCSIHSFVDGFFPTLHSSWILSHTLSHPFQVDSFPTLHSRWILPTLPFQVILSHTPFQVDSFPHSIPGGFFPTLHSRSIPSHTPFQVDPSQLPFQVDSFPHSVPSWILSHTLPFPGGFFPHSIPGDSFHTPFQVGFFPTLRSSGFFPTLHSRWIPSHTPFQVDSFPHSIPGGFFPTLHSRWISFPHSIPGGFLPTLHSRSILSHTPFQLDSFPHSIPGRFFPTLHSRSILSHTPFQVDSFPHSDSGRFLPTLHSTFPTLHPGRLFPNSIPRWIISHTPFQLDSFPHSIPGWILSHTPFQDGFFPATTPFQVDSFPHSIPGRFFPTLHSRWILSHTPFQQVDSFHNFHSRFDSIPHSIPDRFLPTLRSQPIPSRTNSSPISSSRQFFHTSIPSHTPFPFPADSAPTPAAPPSHSRGASDTASPPQAPSHSQGRSLTQLSPATSSNMLKLLHTTFIFRPTLAISRRSRRSWSSSRHPDNACGRLASPTPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWF7</accession>
    <name>A0A423SWF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002659">
        <property type="protein sequence ID" value="ROT68511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWF7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="103" mass="11389" checksum="9F6172A79801B71A" modified="2019-05-08" version="1">MPIVATRAWTKEVVLHVAAAVTRPTSRRRAAAAVVAAAVVLAARRTEERREENGRRSRQDNNSDFMEPDVCDIVEPNDNDDEIINPDEVFDSGLISTDVNKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY49</accession>
    <name>A0A423SY49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002597">
        <property type="protein sequence ID" value="ROT69147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY49"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="762"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="832"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="974" mass="107416" checksum="F2FBAFB9961CA648" modified="2019-05-08" version="1">MGECQDDPSDGQRGRRGRWVRVLAQAPLALLLLAEFGFLMCLYYADVRKGRVFELELDKEEAKTLKNSMRNYVLEIWAFAGVWCVGVHCFQEGLLVLVGWVVSALTFGDDSTQEATVALFHLVVTRPSDYFRGTETPFELAQSSRVYWAAFLKVILQSCYLTGILFYYECTRPQGQKEEEEEPARASEALTATTSEPWREFLSSPASRLTPQPLPQSDATYARFLQDQRTSRGSSSAHSSTVIQIEAPQSRGSRARPDSSRGFTASGPRAPPRSGCRAALRVGSGRRNRALRSGQPIPSPGYKPEQGVRDNDWAACPSRPHLPSVVPRPPTSSERVVQPARGRRTPSTAMANSNDVRIDMGECQDDPSDGQRGARAVGASARSGPLALLLLAEFGFLMCLYYADVRKGRVFELELDKEEAKTLKNSMRNYVLEIWAFAGVWCVGVHCFQEGLLVLVGWVVSALTFGDDSTQEATVALFHLVVTRPSDYFRGTETHSNSQSSRVYWAAFLKVILQSCYLTGILFYYECTRASEALTATTSEPWREFLSSPASRQTPQPLPQSDATYARFLQDQRTSRGAAAPTARRSYRSRPRNLEGQGRAQTAAAGSLQADLGALLEAGVGLRCGSGPGRRNRALRSGQPIPSPRYKPEQGRRPKTSLRPPSGSFSQPEGEGHRRQRWRIQTMSESIWASARTTPRTGREGGAGGGCECSLRPPRLAPSGGIRLPYVSYYADVRKGRVFELELDKEEAKTLKNSMRNYVLEIWAFAGVWCVGVHCFQEGLLVLVGWVVSALTFGDDSTQEATVALFHLVVTRPSDYFRGTETPFELAQSSRVYWAAFLKVILQSCYLTGILFYYEASEPLTATTSEPWREFLSSPASRQTPQPLPQSDATYARFLQDQRTSRGSSSAHSSTVIQIEAPAISRVKGAPRQQPRVHCKRTSAPSSKRVSGCAAGRVGTPKSGSEIGAADSLTRIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZL6</accession>
    <name>A0A423SZL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002537">
        <property type="protein sequence ID" value="ROT69674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZL6"/>
    <dbReference type="OrthoDB" id="6367569at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="934"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="971" mass="108459" checksum="14F42B7A9D61B076" modified="2019-05-08" version="1">MSAATFASYVIGKLSGSDRVDSATSSMASRTSPTPRLTAVWRTKSIPYDVPKAESPTFKSDGSLLKILRTKSMPSLNLEDEIPGRSLRPMSPLSVGSSASSRSASPLPMVMSKTVNPRMGRITMTPPPSPAPSTPPQRRRLARTTSDGALLVKRRQKRSEFECEFPSGGTPSVRALKNMFDAKSDESVAADRSPLSPKEKLPFASPTKSVMVVGQLSEEEPVAAERQMEIVRHGSLDLYEKAEEKNTASILPEIRMPQRSIKELRMRFEQPNKLEETTTPQTHKPPRDSAMQVNIIVEEKALVREVQSEPKPKAHAPVIKQRSRSEPEIITKRPHVLASPVSVKRLKMQFESQGVKDSFASPALLHPCKETTKLRKHFAVRLSSSESEDDVFDMDLPSAVKKPEPMLLEATEASSVTHSVSNLRQQFEKVASAQSSSKTVGRDDVTVRIQWSTTRDLRSTFESAEQNREIQQERPTRPSLSEINPQKTVKNLLQQFQAQTPDPPLEEKTNKFSFEVRESTHSREISNSDVKSYIKSYEASSSPQTRHRSLDGEESEHRDVKSPRHGVFTQQSPAQRQRSSSSSSDSSSDSKEPDDLLISIKRGSAERGEQIENYWRNKEEMLTKKRKENEKSYGYRDNTDADRLENEKLLQKRLIQSSPSESEEEDQNTSGEDEAKWQNIEIKNEIMQMETLVKEALTEPLQTNKAEDSHSKIDVLITDFEKNQEEDSRVRSSSVVLEDLGFESPHGKVGHLIGKFANVRDVDSDDDSSDGDGKSEGKKSSAARSEDTVPDTSTGKVSHLIDKFAKINSRRVKSTSTSSDSDAEKPPVAEKEKPPVPTIPTKNIPGKVRTLNPDELQFFGMGGSSEPFVRSQSLRVKKADPQPFYPRGGSLRVKRTEPLPVIPAAKKLPRNCRYLKPDELRFFDMGNNNNVYSNLTSKSSSQSSSCASIPTMEKDDTFNNNKAPKDVQFFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T102</accession>
    <name>A0A423T102_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cj-cadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_011520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002453">
        <property type="protein sequence ID" value="ROT70199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T102"/>
    <dbReference type="STRING" id="6689.A0A423T102"/>
    <dbReference type="OrthoDB" id="6363789at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF85">
        <property type="entry name" value="SP2353, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Laminin G" evidence="3">
        <location>
            <begin position="95"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="272"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="48965" checksum="BFB4E8369A09074E" modified="2019-05-08" version="1" fragment="single">MPHIHPLPHSPVVVDINTTSLVTPRLRNMQHCHVHEPETCSHNSCLNGGRCAKLSVENREREKGISAHSAPKERPVCRRCVCPGGSWGPRCKVTARTFSGAGWAWVRAPPSCLPARISLRLLIRHPTGLVFYSGPMAPTPRGPDAPPTPLLALQLWQGRPQLLLEGRGGPLKVELNTPLHNGHWHTIHIQLHSKLEETDGDSDSVWPWFGHGVLQLGGMAHTPVRPEDHGWTAAPTSRPMEGCVSDLRFNGQLVDLGEPAASEGSVGGCLPQEEACLGAIPGCGRRGRCVGGLEQPECECEPGWSGLGCKTPTDPVALGRASFVKVALSFTPAPHVLTLQLRMRTRGARDGLLVRVNTHQEDVGLAMHGRPVSDGSWHTVWAERHGHNLVVGVDDGDGWRWNESLPALEGVDEGGGWSPPPPLHVDKNEGITVGGRPEFAGVNLVTVRDDLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1X0</accession>
    <name>A0A423T1X0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative UDP-glucose:glycoprotein glucosyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002431">
        <property type="protein sequence ID" value="ROT70403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1X0"/>
    <dbReference type="STRING" id="6689.A0A423T1X0"/>
    <dbReference type="OrthoDB" id="27683at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003980">
        <property type="term" value="F:UDP-glucose:glycoprotein glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009448">
        <property type="entry name" value="UDP-g_GGtrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040693">
        <property type="entry name" value="UGGT_TRXL_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226">
        <property type="entry name" value="UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11226:SF0">
        <property type="entry name" value="UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18400">
        <property type="entry name" value="Thioredoxin_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UGGT thioredoxin-like" evidence="2">
        <location>
            <begin position="79"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="323" mass="36159" checksum="5CBE76DFBA8A92DF" modified="2019-05-08" version="1">METGQVLRAPTVGSITTKQPSSDPGFDIIILKVRQINAMREILGPLLGLLCFLLTGTTVKCQGKVKPVTTHLSAKWSHTPLLLETAEYMREESIATFWEFVEAVSQKDFTLFTKGSDKAAYNEILGTAGQFLSPSQVSILKLSLSMRVYSPKIEMFRQIALDRNLPTGEDCIAVFDVNGELTCNIEAMKKLVEVGSGTKPVSYDMDHHYPGGENSKVGVTLYAELGTKEFRIHHLAVKELGNSKKKVRLSGYGVELAIKSTEYKAQDDTKVQDDGGRQEEDDEQEVEVEGFLFSKLESLHPEKMEELEQLRNHLVESRHEWHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3E1</accession>
    <name>A0A423T3E1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative zfh4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_010935</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002387">
        <property type="protein sequence ID" value="ROT70778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3E1"/>
    <dbReference type="STRING" id="6689.A0A423T3E1"/>
    <dbReference type="OrthoDB" id="6417226at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000081">
        <property type="entry name" value="Zinc finger homeobox protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051968">
        <property type="entry name" value="ZnFinger_Homeobox_TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45891">
        <property type="entry name" value="ZINC FINGER HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45891:SF3">
        <property type="entry name" value="ZINC FINGER PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24056">
        <property type="entry name" value="zf-C2H2_ZFHX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="422"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="583"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="845"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="854"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT70778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="877" mass="95463" checksum="C1352D8D889D25F8" modified="2019-05-08" version="1">MPGEELGEPPLKGCPPAPPHPPTEPQEAPSQTQQQDPPTMSPEDAPSTSPLAGEEGPGPLPQQGPNATSSSSSASSASPPATFNLTCMTCHTHFTSAEQYTRHHCVASGAAQDAMNESSSDVEKFDGKIVYNPDGSAYIIDSEMSDDDGVAGLELPQHEGSIVDSPRHPLSSTAAPTIPTIANAIYVTKNPAFYTALYGQTFTSLLQENKVPDVPIVHNYRVFTVGDKDSENEYPFAAPQHPAAVRTPDLSRKSPISALGANGRASVSPVTSMSPTSFSPLQSPVTQLTGTVIGACPEHMSGRPQGVSCDKCDLILQQSRTLGGQMAFMHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPENESTCIYCLTNQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGMPNLDGSQALTSQQQSPSGSIYSAPKTPTPSTTPAPPQQQQKPKPMWRCDVCNYETNVARNLRIHMTSEKHTHNMMVLQQNVKHMQQLSAMQGGGGGAGGQMDPMALLQFAGNPAAAAAMMAGLGVGEKPPLPEAALADMAYNQALLIQMMSGGQLPPGGPLGPGGPMGHGPGGPVGHGGHGGHGHGGDHPGPHFDLGLNPESLEPPPEPVPPNPRHAFTCCVCSVFSTDSLEQLTLHLQLDRSKVNENEVLLVVAGNYICKLCSYKTNLKANFQLHCKTDKHLQKLQHVNHILEGGPRNEWKLKYLSNTNPMHVRCNLCEYYTNSVHKLQLHAAHQRHEVLNVLFRHLCMAEHNMHDDRRQYTCVLCNFTTRAKLQLLHHIRSMRHLQMEQLHQIQRHAEGKGGTQQDIGDIFKVEEADEDGRHTPHGKRFRWPGSRGRPRRVGGGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T581</accession>
    <name>A0A423T581_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002265">
        <property type="protein sequence ID" value="ROT71682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T581"/>
    <dbReference type="OrthoDB" id="6381515at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019485808" evidence="2">
        <location>
            <begin position="23"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="326" mass="32458" checksum="1BBC3BC69AC43CE5" modified="2019-05-08" version="1">MILLNSLVKSLAVVAMASIVSAGVSRYSAGGPRGGGRSTSGRRGTRRGGGSVVEAELVGFGILPNRLIDPVLVRSFDRSDSDEGADGYDYGLGFDGGFSAGNPGFDGGFSAGNPGFDGGFSAGNPGFDGGFSAGNPGFDGGFSGGVGFDAGAGFDSGHGGAGFDAGFPGGAPLDAGNVAGHGVFGGVGGGAPFNGPNTGGFGFGAGNAGGFGFNTGFGDGLSFEVDFDDSITAGVGRADVIYPDDVSFDTGLNDDVSFNVGIPDDVSFNIDPVDDVSFNIEPIDDVSFNAGIRDDVSFNVEPADDVSFDAFVGDDSLFDANFDYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5V0</accession>
    <name>A0A423T5V0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Solute carrier organic anion transporter family member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_009758</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cell membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the organo anion transporter (TC 2.A.60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5V0"/>
    <dbReference type="OrthoDB" id="5062115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17403">
        <property type="entry name" value="MFS_SLCO4_OATP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00805">
        <property type="entry name" value="oat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF100">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="619"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="665"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="80"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="11">
        <location>
            <begin position="481"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT71874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="731" mass="78627" checksum="7E110C0B3AD44679" modified="2019-05-08" version="1">MTEVELDPATLPRANSDSGISSQSSTNSEPDTRAMGVGVVNVATSRADLVADDDDEETGECGWLCLRPEKLQKTRTAKWVLFWLCWAAAAQGMVVNGFVNVCITTIEKRFDLRSTDTGLIAGAYDIASVLCSIPVSYLGSRIGSSKPRWLGWGVFIMGIGSFVFTLPHFGSPAYDPSVSTSSLLVCLREGKRVSRCGVMVEKWLSSYRHIFVLGQFLHGVGASPLYTLGITYLDESVPVKMSSMYLGIFYAMAVIGPAFGYLLGGQFLKIYIDSPKVDPTNLGLLANSDLWLGGWWIGFLLSGALSILVSWPIMAFPAQLPGAKAIKADRVSEAHSSPDTATSGGARGFGRLRDLPKAIKILTFNPTFVFLSLAGATEGILLAGFATFMPKFLENQFSMSASFAALLVGFVVVPAGGGGTFLGGWLIKRLQLRCSGILKFCIVFSFFCVLACLTFVMSCPNTQFAGVNVEYDNRTITPSTPNLTAFCNDDCNCKDVPYDPVCGNNHVMYFSPCHAGCSGMEKGADGLKVYTGCRCVASLPLPPLTTPIPKSGVGADVRLAVDSAIREKCPSTCNLMLVFLVIFFVVMLLTFVISLPAVSATLRCVPDSHRSFALGLQWIVVRLLGTIPGPILFGALIDNTCTLWQTTCGTTGACRSYDNFYMSRYMMGISIIGKALSTITFFMAWWLYKPPATGPETCHANAVAVADTVPVKDPKEAKELSGIDNPAADLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6A9</accession>
    <name>A0A423T6A9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ankyrin-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_009642</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT72022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423T6A9"/>
    <dbReference type="OrthoDB" id="6358812at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
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            <dbReference type="Proteomes" id="UP000283509"/>
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    <sequence length="2841" mass="310955" checksum="32D72C98DE9D5E2D" modified="2019-05-08" version="1">MQRCFSSGDLRERGIDSSVLAAGCLETDGSASFLRAARAGNLEKVLEFLKTNTDINTCNANGLNALHLASKEGHVSVVTELLQRGANVDAATKKGNTALHIASLAGQEEIVKVLVQHQAMVNIQSQNGFTPLYMAAQENHDNVVRFLLANNANQSLATEDGFTPLAVALQQGHDKVVAVLLENDTRGKVRLPALHIAAKKDDTKAAALLLHTDHNPDVTSKSGFTPLHIAAHYGNENIANLLIQRGADVNYVAKHQITPLHVASKWGKGNMVSLLIDKGANYEAKTRDGLTPLHCAARSGHDTVVDMLLEKGAPITSKTKNGLAPLHMASQGDHVDAARILLYHKAPVDDVTVDFLTALHVAAHCGHVRVAKLLLDRKADPNARALNGFTPLHIACKKNRIKVVELLLKHGASIEATTESGLTPLHVASFMGCMNIVIYLIQHGASADVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTALHIASRLGNSDIVVLLLQHGAAVDATTKDHYTALHIAAKEGQEEVASVLLEHGASLTSTTKKGFTPLHLAAKYGNMKVARLLLQKDAPVDAQGKNGVTPLHVAAHYDHQNVALLLLDKGASPHATAKNGYTPLHIAARKNQMDIATTLLEYGASANAESKAGFTPLHLSSQEGHTDMATLLIEHNAAPGACAKNGLTPLHLCAQEDRVNVAAILVKHGAQIDPATKAGYTPLHVACHFGQMNMVRFLLQHGAKVESSTQLGYTPLHQAAQQGHTQIVNLLLENKAEPNAETKDGKTALSIAQRLGYISVVETLKIVTETTITTTTTTVTEEKYKVVVPETMHETFMSESEDEGGDDNLVSSMFGKQQHVTLPFYEGQLRYTSDDTMLGDQSYRYLTADEMKSLGDDSLPIDVTKDEKMDVSFISNTMAAPPVAPVDQLSPQHQKEQQYAQYTGHYPSDNVDIAKTPILAGPESLNTTLNTTIDSAMIESQIIPTQVANQLSAQVNQTQVQQPVGQSAKGQVPADQDSVPEKAAEILSGWEGFLVSFMVDARGGAMRGCRHSGVRVIIPPRKAAMPMRITCRYLKKDKLVHAPPLMEGEALGSRILEMGPAGAKFLGPVIIEVPHFASLRGKEREIVILRSDNGETWREHTLEATEEAVQEVLNESFDGEELKQLEDLNTNRITRILTTDFPQYFAIVTRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPIPTDLVAKLLGNRVAVSPIVTVEPRRRKFHKPITLTIPVPQASSKGMINQYSGEAPTLRLLCSITGGTTRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCSNIPEATKMATELYREAIHVPFMAKFVVFSKRHQLEEARVRVFCMTDDREDKTLEQQELFVEVAKSRDVEVLEGKPQYLEFAGNLVPVTKSGDQLAFNFYAFRENRLPFTVRVKDQHADPIGRVAFMRQPKVGRGDPPQTPICNLNIALPDNIQPEPAPSEPDLLALEKKYSFLSISKADTIHKADLRLTDISNMLGTDWVGLARELEISDSDINIIKSQYPDNAPKQAIVMLRLWMQTSGNKANGNTLEKGLRKIGRDDIVNQCIFNVELVTDDIERAMAKAHLDQSGFDAFRYELGPSRDTTLNRDVSLDVSYDEQDMMKEAESAEEEEENQRSYQDKTRREQHTADMSPTYESEEKKYAGEEKIVTEEKITKEEMKDGSAVTVTTTTTSVVAEPVTESKKEAKDKTIITEKVVPEDQKAPPAKEAEKVEDKVPKPEKKEEKPIVLDKAEEKVVEKVEEVVVEQKVEEKPVVKVVEKSAEVGEKAKDASEKLEEKAPEVPPASLDEAQKAGTTTATEVITGPDGTTTSSTTTTTERRSFTTADDGTVKEHIVIEKKTTSFVDGMEKGEDKSEILLKLGEELGRLDEQLEERFKEKRKAVEPEDGFTQASVESRQMSSTGGTTEVSTKGTAITTTQPVIGDETVMQMGQDFVLELPLSHYHHHTCSPSTTTAPHHHTRVLGGGEEAAARRAALIQQRTSRPDSRRAAQDVLQWDTPLEDSAYKTRLEDGKEQVLSNDSTKAGQTEERGCSPITVLEARPEVDHVATRPRSRAGSHTITTTTSWGAPVTTTTSIEVDDDQSARCVQLTLHSESRVTLHAPGGVWEGLHGVEQQPEHQDEEQQPHEDKHVGDNDVPAEASPDAGPENKSEGETLTEQDFYDDIHQAKDAHELESKETECAIPALSGDDSAYLASEATAPSAHRPTTLMITSNSNESTDDAECTANDLTKLGREDDIPKELKEETSVTEMEDLEEQGMGELAVSERPPGSESGAVPRPERPARPAPRTTTLVKVKVEKRPITSHLLVRERSVHEHQPTVHVPSVEEEVRGLMQEVKEATSQIKQEVKELRQADTPTPDTPTPLREFKEFLNREEEQELERLPTIKEMCRESEEDASGTVGGEHLRGHEHLRLDLDVPTLGRPIPVQAVQRSGDDSSHPDSGYSTLEGYYAVGVDPYHTSKYKSCSEPVPEGSPSEPSIKSELESPSSLVDSSDLSPVDSASATEEKGRRFHAENLSSGNITSLAVNMPVGTQMETTTLGVPGGQSPIGEMNGQDIQDALTDVEDLNMDGESPIPKQKQLLLLPEKETGAVTDTEDMDLSGDENDIIPEKANLPTIQDLGVLPEPTKEVINLTEGYAREASPLLLSDSDSEREDVQNRHKKNIKKGEKMSELEVPGDDEPEGVTDVEDMVASGDEIEEQVQVEDSLPDHYLDQGEGVSNQEKMKAASPKPKVFKHHEDSSDDEKRSKKQVRRRSKASLTVQPKEDGTTDVEDLLLLVTQVGQQIQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6J8</accession>
    <name>A0A423T6J8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable U2 small nuclear ribonucleoprotein A'</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_009508</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the U2 small nuclear ribonucleoprotein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002202">
        <property type="protein sequence ID" value="ROT72124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6J8"/>
    <dbReference type="STRING" id="6689.A0A423T6J8"/>
    <dbReference type="OrthoDB" id="433501at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000026">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044640">
        <property type="entry name" value="RU2A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10552:SF6">
        <property type="entry name" value="U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00069881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT72124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="247" mass="28424" checksum="ACC59FC0729DC876" modified="2019-05-08" version="1">MVKLTPELIQQSVQHINPVRDRELILRGYKIPVIENLGATLDQFDTVDFSDNDIRKLDGFPLLKRLKSLLLNNNRIVRISDTLPEELPNLQCLYLTNNLVQELADLDNLAGLKKLEHVSLLGNPVTTRDHYRLYLINKLPQVRVVDFRRVRMREREMAKKLFKSKLGKEIQKEAKKARTFVAGSGIMDSRPALNQMTAEDQAAIRQAIANARSMEEVERLQHMLRTGNIPGRSQGIKRRHGEEEEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBY8</accession>
    <name>A0A423TBY8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001956">
        <property type="protein sequence ID" value="ROT73979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBY8"/>
    <dbReference type="OrthoDB" id="10490087at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="310" mass="32792" checksum="4F0ADE16CFA72795" modified="2019-05-08" version="1" fragment="single">MDSEGRTRSGANRSSSRRGPRSDWRSSNQSGSANSSANQYSSSDEDPEVSRNTGRGYRSAQRTGDRGSNRSRATTPLSHTSDPDVGDPPSLVSLQDAAHAHPNNLSHYRGHSAHGHYYQEIPQTGHHYANHLDEYDSPVVKGSRKYPQGRRMPGGGSSLSSSDNNSDTTYAESDINSSLRAKMAALDNDAAGTPPDPAPPEVPIRGPSHHHPLLAASRRAGGAPPASNNTGVGGPPSPHYQDHLQDDTYQQPNSNVFLSQGGNTCYEYLMSGGSPRYGTGTAAKSPGAGGAVLYGPSTTPDYLSINNSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TE32</accession>
    <name>A0A423TE32_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative homeobox protein Nkx-6.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006737</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001850">
        <property type="protein sequence ID" value="ROT74754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TE32"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007417">
        <property type="term" value="P:central nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050877">
        <property type="entry name" value="EMX-VAX-Noto_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339:SF67">
        <property type="entry name" value="GNOT1 HOMEODOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339">
        <property type="entry name" value="HOMEOBOX PROTEIN EMX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="87"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="89"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="165" mass="18840" checksum="566DFFD561D5DF04" modified="2019-05-08" version="1">MDQLSVMNFQPLTWAFSHPWAPPVSPPPAHSITPSRMSHKAKAFTIDALLGLDTQKDLPAPTASPPASPLSLLQRESSDTGLRDAPGKLKRHRTVFTDSQLQRLEEEFQRQQYLVGPERRYLARQLELSELQLKVWFQNRRIKWRKNQLSTTQDRDACASPPTSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFU5</accession>
    <name>A0A423TFU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative Kv channel-interacting protein 4-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006137</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001785">
        <property type="protein sequence ID" value="ROT75326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFU5"/>
    <dbReference type="STRING" id="6689.A0A423TFU5"/>
    <dbReference type="OrthoDB" id="6351256at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF185">
        <property type="entry name" value="NEUROCALCIN HOMOLOG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="178"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="521" mass="59668" checksum="4AB7BAEC51E3EF68" modified="2019-05-08" version="1">MARNRIISRKPPSHPPSFRPPDDDGGDGLSFHVQRYRPEELEKLAKTTKFSKKEIQLIYRGFKQECPTGLIDEEGFKEIFSQFFPLGDATHYAHYVFNTFTRNHHGQISFEVCLPRLLSLARLYSGSRAGKKEKLQWIFGLYDVNNDGLITKAEMVDVVSAIYEMMGRSTEPQVEETSAKEHVEKIFHLIDANQDGAITIEELAQPRACFQIFTMGKQKKDIGEFGYMRRIYNGLAEEIATLQKRLKELDKKERFLRAEALKHQVQLTADSEIKCILKSKGDSIHLTEEHTDIVKKQREGQRTVSANHVISARVEVEAVEGMDEEEEEEQQQQQQQKSRSAPAELGLLKRWKVEGKIGECSYSISFLAGCDLENPLGTILQIENLSATEGNPVIQDIIDYKQDGPFKVQQLSNLLFGLQMMYEERNEAIDQLKDIPNLEVQHAIEPVTIEFEPQEGYHIKIVWKIGFDTRNMRVINIIEVVCDDEVTARFSRSTGFPYLSGRETITTPKGVLEFVESYMDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFV3</accession>
    <name>A0A423TFV3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_006090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001780">
        <property type="protein sequence ID" value="ROT75374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFV3"/>
    <dbReference type="STRING" id="6689.A0A423TFV3"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014434">
        <property type="entry name" value="Monothiol_GRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF16">
        <property type="entry name" value="GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005894">
        <property type="entry name" value="Monothiol_GRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="9">
        <location>
            <begin position="2"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT75374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="96" mass="10751" checksum="3D5C159B7A13A3A8" modified="2019-05-08" version="1">MPRCGFSNAVVQIMRMHGVNYDAHNVLADDSVRQGIKEYSDWPTIPQVFINGDFVGGCDILLQMHQSGELIDELQKVGITSALLEQEMENDKGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGU1</accession>
    <name>A0A423TGU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oplophorus-luciferin 2-monooxygenase non-catalytic subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001739">
        <property type="protein sequence ID" value="ROT75720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGU1"/>
    <dbReference type="STRING" id="6689.A0A423TGU1"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF96">
        <property type="entry name" value="LEUCINE RICH REPEAT CONTAINING 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019215278" evidence="4">
        <location>
            <begin position="20"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="399"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="46923" checksum="69BF1B98870F1552" modified="2019-05-08" version="1">MWSSSLFTKIALLIGVASCDITIKSPASANNTVVSNVSPCPEGKDIWPCICFEKDDLWADISCQDVNKEDLYTIFGADFPDPELNAIRVERNLELTTLPEDVFENVTFRALVFREGILEDVKAGGFNGGFSTALSLDFTSNRITSFPFGSLQNFAALTELLLGNNSIAGFPSMKSATLQVLSLAHNPLKALPSWAFVHLPALVSLDLDHTGLTVLQPGTFASLKSLAYVFLAGNQLTHVGADSLAFVSTALKVVSLSHNAIKSVDGISGLGTETGVFLDSNNLSEMPEMIWRPWLERGVKVWVLGNCQSTRSNVMAEQQTEFPDTPAPTIPLFAREPTLPLLRIPPSLLLWSFYPPLVHLPLSDLPSPVFLNTYALLPPVARIHTTLLEFLSPHPPLSPKFPPLPHPSPNKVNKPHPSSQPTPPTPLLKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJD6</accession>
    <name>A0A423TJD6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004843</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001641">
        <property type="protein sequence ID" value="ROT76572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJD6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="73673" checksum="2F93EAF682425E0C" modified="2019-05-08" version="1">MSCSFFPYISPCFLSSYLPSLPPCQSSIPILILSFSSLHSSYYLSHIPSLLPSLPPFFPPILPLFSLLPSLPPSLLSSLPPFFPIPPPSSPLLSSSPFPSPYFCTSVWHVPSSPLSLPSLFLFLLSSLPSTSHFPFLFLFVVLFLFSFLSSRSSAHPSFLPWNRYSLFSNPPPSLLSSLLHPSIPFLPPSLISPLLTFVNNSLLLFSSFLYPFPYPSLPPTIPPYFSFPHLLFSLPPPIYPSSPLFPVLPRSLFPWIIRIKSRYLFWRFSPLPLPPSSLPLCFLLSFFFKPFPSLPSSLSTLLIHPFSPFLRFHSFHPSLLSPSLYKGFPPSLQPFSYILSPCRFPLLSLFSSLLPSSPFLPPFLLPSPSSSLSSPRIIRIKQTSSLPALSPPSLPLPFPPLPPSPSHPFPFPFPPSVAFFSPRIIRIKQTSSLPAAPPSLSPFPSLLSLLSSLSFLSFFLPFPFPPSVAFFSPRIIRIKQTSSLPAAFPLPLSPSLPSSPSSPSSPSHPSFSLSLSLPPSVAFFSQNYTDKTDIPLSPAFPPLSPPFPFPPLPPLLLSFLSLPFPSSNITDKTDILSPCRFPPPSLPSLPPLLLSLSPIPSLLPSLPFPPSVAFFSPRIIRIKQTSSSCRFPLPLSLPFPPLLLSSLSSLPSFFLPSLPPSLSSPQELYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKI2</accession>
    <name>A0A423TKI2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Zinc transporter ZIP3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Solute carrier family 39 member 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Zrt- and Irt-like protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_004406</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Zn(2+)(in) = Zn(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29351"/>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29352"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Apical cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001585">
        <property type="protein sequence ID" value="ROT76962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKI2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF221">
        <property type="entry name" value="ZINC TRANSPORTER ZIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00036307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="233" mass="25667" checksum="CA209F7979C594D6" modified="2019-05-08" version="1" fragment="single">ELGHTHEWETFAEFPWGFFVVTCGFLVIFTIDKLVHAMEHAKQGSGGTNSHILLQKSSSTTFSSRCEDPEATDSSSDCQNCHELEGGHDVPSSVIFLVALGIHSVFEGIAVGLQTEKDKVLEFSVAVLVHETVMAFTFGMEVSKSQVLSRWSKAFYVLVFTSTIPVGIAGVGLRTRPRRTGRSCPPFWRPSRVEPRLQAIGIPASGLNPCLRLAEPRLQLGTTRAKVEREPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLN1</accession>
    <name>A0A423TLN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative trypsin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003972</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLN1"/>
    <dbReference type="STRING" id="6689.A0A423TLN1"/>
    <dbReference type="OrthoDB" id="6368789at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050430">
        <property type="entry name" value="Peptidase_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276:SF98">
        <property type="entry name" value="FI18310P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24276">
        <property type="entry name" value="POLYSERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="13466" checksum="0DB3F30E2E0AA59C" modified="2019-05-08" version="1">MPPPNPTYAGKTATATGWGTTSSGGSSSDTLREVDVTVLSNTACQSGSYGSAIKDTMLCAGSTGKDSCQGDSGGPLVFKDGGGNYDQIGVVSWGYGCGARGYPGVYTRVNSYLDWIRTNTADGVYCKGMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMJ3</accession>
    <name>A0A423TMJ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phospholipase A2</fullName>
            <ecNumber evidence="3">3.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Phosphatidylcholine 2-acylhydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_003654</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.4" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001497">
        <property type="protein sequence ID" value="ROT77657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMJ3"/>
    <dbReference type="STRING" id="6689.A0A423TMJ3"/>
    <dbReference type="OrthoDB" id="10059604at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050482">
        <property type="term" value="P:arachidonate secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.90.10:FF:000002">
        <property type="entry name" value="Phospholipase A2 group III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.90.10">
        <property type="entry name" value="Phospholipase A2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016090">
        <property type="entry name" value="PLA2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033113">
        <property type="entry name" value="PLA2_histidine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036444">
        <property type="entry name" value="PLipase_A2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12253">
        <property type="entry name" value="RH14732P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05826">
        <property type="entry name" value="Phospholip_A2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48619">
        <property type="entry name" value="Phospholipase A2, PLA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00118">
        <property type="entry name" value="PA2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Phospholipase A2-like central" evidence="13">
        <location>
            <begin position="22"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT77657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="17017" checksum="A4ADB516D0448231" modified="2019-05-08" version="1">MMIANGELPQTLAKCEKFSIGAGTKWCGTGNVAEGLDDLGTLKEVDACCRDHDLCPDDLEPGQTRHNITNESPFTMSHCDCNDNFRKCLHDVGSGEANEVGSAYFSTGLFQCYRLAKPTAGCKQWAGLLTQACQEYNFNEDGEPRWQVFDMKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMT7</accession>
    <name>A0A423TMT7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001481">
        <property type="protein sequence ID" value="ROT77770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMT7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="43322" checksum="6355DC199603CF84" modified="2019-05-08" version="1">MLMRLIRGGGGGGDRTIYRIIFIAHPRLPPSSGRPPLPFSSSLSSSLLFTLHHSPRLPSPPPFYSLSSIRPRPSSFFVHLVFLLLLPFIHSPPFALLPSSFTSSSLSSLLLTLLHSPSPFLLHHSPRLPSLPPFYSLSSIRPRPSSFFVHLVFSLFLPFIHSPPFALALLPSSLFFPSMFPFPLFLNSSLLPGFLSLASFLPSYSFSLPHLSTSVHPHFLLFLPFLYLIFFHLLASNFFPLSLYSLILRLFYDLSLSILISFPPLPLQFFTEPIPALRHSDPSRCATTLHRLTTPATETERQTTPTNARRGRWNRGGFRGMANSVVECHPRASLSLSLDFASRVTPPATPPSPRPPKPGQSRLIPLNHTLPCTPTAPSLAPSLPAMEGEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNY5</accession>
    <name>A0A423TNY5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adenosine deaminase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_003135</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-methyl-AMP + H2O + H(+) = IMP + methylamine</text>
            <dbReference type="Rhea" id="RHEA:16001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:59338"/>
            <dbReference type="ChEBI" id="CHEBI:144842"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16002"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001424">
        <property type="protein sequence ID" value="ROT78153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNY5"/>
    <dbReference type="STRING" id="6689.A0A423TNY5"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00443">
        <property type="entry name" value="ADA_AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000033">
        <property type="entry name" value="Adenosine deaminase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF42">
        <property type="entry name" value="ADENOSINE DEAMINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Adenosine deaminase" evidence="11">
        <location>
            <begin position="11"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00057464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT78153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="354" mass="39963" checksum="27D22C9B73EE41BD" modified="2019-05-08" version="1">MDLSEYCKSLPKIELHAHLTGSLSDETVLKLLRAKQAEGGANLPQSAEVTIQRGHKRTLEECFEVFRILHCLTDNLSAIKTIARDVIQEFVADNVRYLELRTTPKSINGVMTKNQYIDTVLEAMIDEMKLNTITIRLLISIDRSRGLDDAWDTLQLAKQYAAHERFKNLICGIDISGNPRAGNLVEYIPVLREAKQCGLKLSVHLAEVVNEKETLEVLKTELIDRIGHGTFIHPETGGSQELMQLVKDQGIPLELCLSSNIKSGTVKSAEAHHFSCWRKDKHPVVICTDDKGVFSTTLSEEYKICAETFHLKKTDLRELCLAAVEMTFLSQEEKDRLRQTILKDLDKLTHIESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRV4</accession>
    <name>A0A423TRV4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001278">
        <property type="protein sequence ID" value="ROT79195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRV4"/>
    <dbReference type="STRING" id="6689.A0A423TRV4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="44108" checksum="2777A5E81E427565" modified="2019-05-08" version="1">MVAISKRLSSECRRATHIPFFFFSSTYATPPTHLPPYRKSNPPHLPPPYYESNLLPTSLLSRVQPTHPLPPLPRPTHPPPPSLTASQPPLPYRESTHHPPPFLIATNPPTTSHPRVNPPTSSLPYRESNPPTPSPLPYRESNPPTHLPPSLPRVQPTHLPPLPPASPTHPPPPLPASPTHPPPPSFTASQPTHPPPPHRESNPPTTPSLPYRESNPPTPSLLYSESNPPPSLPPYASPSLPPYSESNPPTPSLPYRESNPPTPSLPYRESNPPTHPPPSLPYGESNHLPPTHPLPYRESNPPTHLPPLPRVQPTHPPTALPLSPRVLQVPNAKRTLSGRSCKQSDALRQVTRCRAVFPSASDLYLPPPGPEGVLQEGPRHSCCSRPCRSRRLGERAGDCVLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TS49</accession>
    <name>A0A423TS49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_001980</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001261">
        <property type="protein sequence ID" value="ROT79300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TS49"/>
    <dbReference type="OrthoDB" id="6377023at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF39">
        <property type="entry name" value="IONOTROPIC RECEPTOR 56A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13384">
        <property type="entry name" value="HTH_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="12">
        <location>
            <begin position="180"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="410"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="477"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT79300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="727" mass="81609" checksum="EF94875034D2F723" modified="2019-05-08" version="1">MRHTTLTDLARRLHSCSIYVHLPFSTKAKVVHVASWTASQELSLKAKTALFPEKFNNFHSGLINITALPFRPYWVEEVTEAADGTILKTYAGSDGQLMNTLAERLNFTFRVMEVKDWDEVTSKVVERKAFMSGVYHVLLPQRRKRYDFTFAYERAITEFSMAKPALRPRWQSLYYPLDENVWFCILALLALTPLFALLIICGGKLAHKDEQADARTVTLEMVGSLLGQSIAERTGQRSGGRVMLASWLIFAFILTTAYRGNLTAALTLPKYPPRVETLPELVGVVDKITMPPYGAEFKEFFSQSDSIVFQTIAKKMQLVSNILDGLKGINEKQSHMDGERYLRLAIAEHFTLADGSNRLYVGRGSVLPTIAGLPIPHDAPYKPQVDRLLMTIIEAGLYEKWSEDMLNQARREGRQRERNLKKLQETGKDNVETEGSDDSIKALTIVHMQGPLMLLLLGLILALMVFVVEGVVSSHYNSALDPPPTTRVSRREEPITPKGEISTNQIKASEARSQPPCAGVPLRKRRGTTSRRHTPALHLLRNGCLRSFLFLWAVAPRTPPPCRRPLVHTRRDERYAIVRLWQSGLSARLIADETGTSTTTVYRWVRRWQEDGNVENKPRVDRNPFCSLGLAPGNDLAPGNSLQSTVASHFLRNFELSSTWPKDFLAPYAPPRDQIGPFAFHGESTTLPQQISLTTPSFSVSSPPLVSLACFPPADRISWTQPKNSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTD7</accession>
    <name>A0A423TTD7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-soluble NSF attachment protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">N-ethylmaleimide-sensitive factor attachment protein gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_001566</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001200">
        <property type="protein sequence ID" value="ROT79702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTD7"/>
    <dbReference type="STRING" id="6689.A0A423TTD7"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000477">
        <property type="entry name" value="gamma-soluble NSF attachment protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF2">
        <property type="entry name" value="GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT79702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="323" mass="36001" checksum="ED0CADFB6FB3E984" modified="2019-05-08" version="1">MAATKKIEEALAHIREAEKSLKTSLLKWKPDYDVAADEYNAAATCYKTAKQYTQCRECLLKAVEYYKLNRSFFSAAKCLDQAVLISKEMGDLDNVFKFCERAACMYQEHGIPDTGALSLDKGAKIIEHQLPEKALHLYEHAVDIVMIEDRPRQAAEYQSKVNRINVKLQKYDAATDSIRREIGYHQASENNPAIGRLAVALVLVQLARGDPVAAEKAFREWGAYCDQEEVSTLEMLIQAFDEEDGDMARKALNSPFIKHMDVEYAKLARSLPIPKTSQESKKPGVTDTYPPYTSSAAADVGSITKGVADTSISQGEDEDLDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWH8</accession>
    <name>A0A423TWH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Steroid receptor RNA activator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000501</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001073">
        <property type="protein sequence ID" value="ROT80762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWH8"/>
    <dbReference type="STRING" id="6689.A0A423TWH8"/>
    <dbReference type="OrthoDB" id="5982138at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009917">
        <property type="entry name" value="SRA1/Sec31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040243">
        <property type="entry name" value="Steroid_recept_RNA_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18834">
        <property type="entry name" value="STEROID RECEPTOR RNA ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18834:SF2">
        <property type="entry name" value="STEROID RECEPTOR RNA ACTIVATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07304">
        <property type="entry name" value="SRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRA1/Sec31" evidence="2">
        <location>
            <begin position="78"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="266" mass="29362" checksum="D879E4319B5B217E" modified="2019-05-08" version="1">MEPIGPGSHDRAWNDPPKFAFNASATAGGQSGRRRLMNKRVPIPIGPSDGTAPVSPSLRPTDGPPKDGDLFRMKGPHGPPPTVSPAVSKLPDAKAEKEEKKKGDPLIEENLNTEEMLSEVKTALDESLEKVSDELKKSVLDDITRRLEMMKKMWIEGELDPIVQRRMLLLARAMRESNYDEAWDIHQGLIVDFTSVCSSWMVGVKRIISDFRKTEKEAAPEVAEAEVKTTDGEEKEAEELTKDVSEGVSNLLVQPEVHTKEGDAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYW5</accession>
    <name>A0A423TYW5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_025217</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01000944">
        <property type="protein sequence ID" value="ROT81637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYW5"/>
    <dbReference type="STRING" id="6689.A0A423TYW5"/>
    <dbReference type="OrthoDB" id="6354871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="271"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="460"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="147"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT81637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="689" mass="77621" checksum="B51F9C1BA2766062" modified="2019-05-08" version="1">MNEGGGDKKKPKKKPRKRGGNGGAAKTVKQQLPQDKAERVAPHHLITKKRSAENGDNQQPKKTVKQQLPQDKTERVAPPQPQDKTERVARPQPQNKTERVARPQPQDKTERVAQPQPVDKKCPAENGDGQKPKKRKPRKKKLGGDITEAKQNIDVKKKETEKTKAGETKSNPGERRSNTGETKTVVTGEKGELVKKRKKIFKKKKKPKENQSTVEKIDNQSTVELIDNSNFDFGNSERSFKNLEGSISPKTLRVLQQLGFKEMTEIQAKAIPKLLQGLDLRGTAKTGSGKTLAFTIPVIELMSKLNFMPSQGTGVVILSPTRELSIQTRDVLAPFAKAHSLTMELIIGGTNMKTEAAKLRQGVNIIVATPGRFLDHLRSTKDFIFKNMACLVLDEADRILDTGFEHDLKKILQHLPSERQTILFSATKDTKTNALAPLALKANPVEVDVDSDKNEATVDGLEQAYVVCPIEKRVSLLCRLIKENQDKKVMIFLNSVWNVKYYHHILNCLEVPVSLLHGRLSQNKRTDGFFTFKNQTKGTLLCTDVGARGWDIKGIDLIIQFDPPSDPMEYIHRVGRTARAGDSGSAILFLQPHETNFISYMKSHSVTLPHMDISWREVEELQVEELNQHDEHLSNMGKKAYRAFLRSYMALPLKSIFDPSKLDTLRVARAYGFNKEPLKVRLFRKEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYX4</accession>
    <name>A0A423TYX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_025174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000937">
        <property type="protein sequence ID" value="ROT81665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYX4"/>
    <dbReference type="STRING" id="6689.A0A423TYX4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="53035" checksum="359B6DC915248FEF" modified="2019-05-08" version="1">MAECLAAARCGVEMEQLAVPTRRFEGKHSRFVPAAGTCFASRPSVFYFAGQQEPLISPSGYQGSFATPRLPSPFLRASCPPPSPCPSFPPSCPLPFPVPLALPFPSCPSPFPRRLLPLSPSPAPLALPPVAFPRASLHPSFPRSCPPPLPRASPPLPPRALAPVLPPLPCPSSFPQPCGPSSSFPQPCGPSFCVPTLALPPPSPNPVAFSPSPTLWPSPPPTLWPFLLPLPFTLWLWPSFSLPVAIIFLASSSSQPCGLLLLPNPVALPLPPTCGPSSFPTPVALTLLPQPCGLLPSFSTFSSFPNGGSFPPSPNPVALPSFPPLAFHLNPVALYPPPSPNPVAFLPSFPQPCGSSFPPSPTCGSSPPPHLWPFLLPQPCGPSSSFPNPVALTPPPTLWLPSLLPNPVALHPSSPNPVASPSPTPALPSLLPNPVALPLLPNPVPFLLLATCGPFSSFPKPWALLRLPNPVALPPPSQPCGPSSSFPQPFEVLFTLGVRGSRTDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4Y9</accession>
    <name>A0A423U4Y9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000637">
        <property type="protein sequence ID" value="ROT83749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4Y9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1009" mass="109780" checksum="651081FA3FA0468C" modified="2019-05-08" version="1">MSLDSSSFGDRPSTPDSSSSLTRLSLLLSTPLVSCRSLLFSYRPSSSSPIDRLFVSCPTPLVLSTPPRLLSDCLLVSYPTSSSSPIRPPPRLLLDCLLVSYPPASSSPIDRLLVFTRLPLRLLSDSSSPPPRLLLDCLLVSYRCLLVSYVSFLSDSSSSLTRLPPRLLSTASSSPIRPPPRLLLVCLFVSYPTSSSSPIRPPPRLLLDCLLVSYPTASSSPIRPPPRLLLVCLFVSYPTSSSSLTRLPPLLDRLFLLSTRLYSVASSSPYPTSSSSPIRPPPRLLLDCLLVSYPRLYSSRLLVSYSDYRPSPTTSSGLLLDCLLRLLFRPPPRLYSTASSSPIDRLSSLSASSSSLSGLSDCLSSPIRPPPRLLLDCLFVSYPTSSSSPIRPPPRLLLDCLLVSYPTASSSPIRPPPRLFTRLPPRLLYLLLVSYRPLRLLSDLLLVSYSTASSSPDCLSSPIRPLLVSYSTASSSPIRPPPVSTRLPPRLYPTPPSSPIDPPPRLYPTPPSSPIDSLVSIRPSPRLLLDCLSSSPIRPLLVSYSTASSYRPPSSLTRRRLLSDLLLVSYSTRLLSSYRSLFVSYPTSSSSLTRLPLRLLSDLLLVSYSTASSSPIRPPPRLLLDCLSLYSLPLRLLSNSSSSLTRLPPSSFLSDLSSSSPTRPPRSPIPGPRIRPLLSPRLYSSSPIRLPPRLLSDLLLVSYPTSSFCLLLDCLLVSYRSSRLLLDCLLRLVSSRSTASSSPIPMPPRSLTRLPPRLSPLLSDCLLVDCLCLLSDSSCLLSTSPRLLSIVSSSPIGASFVSYPASSSPIRLPLLSPIRPPPRSLFRPPPLSYPTRLLVSYRPSASSLLVSFSSTLLLSGLYSTASSSPIPDTPLRLLSTSSSSLTRLLLVLLSDASSSPSDSSRLYSSASSSPIRPSSSFLSISSSYLTRLPPLSYRRLLVSYRRALVFLSDRSSLLSDRLLRLYRPPTLSIDLLLGLLLDCSSSPITGSVPIRPPPRLSIRPLLVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5R6</accession>
    <name>A0A423U5R6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000601">
        <property type="protein sequence ID" value="ROT84057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5R6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="577" mass="62666" checksum="59EA6B95501E28AC" modified="2019-05-08" version="1">MLILLFSTLPLLKNQNHFFPLHLSLSSPPTFLSFPSHAIIFFVCLLPIFLDPTFHLPSPFLLPFFPFSFSLPLLLINFLSLYYPHFPLLPPSLSIFFPHPLPILSLSLSFSPHFPPFYTLHTSPILSPPPFCPPLLSCHIPLLSFSSLSPLPSYPPHTPSSSYAPPYPQHPLTPPQHTSFPLPLPFPPPSLPPTPHHKPPYLIPPTLPPTFPYPTPHHAPPPPPTAPTPLPAPHPPAPHASQVLFPLPIPLLLLYHLPPSLLHPFPRPPPTSTFLSPFSSTSSSPSLHSLFSLPPSTPLLSLHPHPLHLPPPLLSPSSTSHTNSTPSIPALSTPPSLPPSLSQPFHHPSLPPSSPLHFLPLPLLRTPSPPPPPFSQQPPSLHSLIYPTPFYHPSPHPPPPSLPQQPFTSTPPSSPPPTSSSSIPPPPSYCPLPSSFLQSLVLHPLSHPLLDSTTLSTSIDIPLPPPLSKVLPPPPSPSLKILPLPPSPVPQRSSSYPLPSSPLPSLLLSQQSFPLSQQSSPSSPFPPSPNSPSPSPPLLPCPQRPLPVLPRGIRLGYETKNWTEIKEKSIFEKKSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6C5</accession>
    <name>A0A423U6C5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000577">
        <property type="protein sequence ID" value="ROT84242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6C5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="119" mass="12123" checksum="FAEF236D629A219E" modified="2019-05-08" version="1">MKEGERPEEAKTAAGATRVRSPFRGAAVRSQRMLRAGALVFVGAALSAAGASYVSSAGGLSDAFLRELVARMGSGLADPPGTTWTFLLKAFWESEMDSRNALSQAPGGVATAAGPAGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6J7</accession>
    <name>A0A423U6J7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hyperpolarization-activated cyclic nucleotide-modulated cation channel splice variant ABsC2-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6J7"/>
    <dbReference type="STRING" id="6689.A0A423U6J7"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098855">
        <property type="term" value="C:HCN channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003254">
        <property type="term" value="P:regulation of membrane depolarization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051413">
        <property type="entry name" value="K/Na_HCN_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45689:SF5">
        <property type="entry name" value="I[[H]] CHANNEL, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="93"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="331" mass="37325" checksum="BAEDDE11127A821A" modified="2019-05-08" version="1" fragment="single">ECKASVRATRPRSFLLSDSAHLRAFGLQLKQVEEYMAYRKLPRELRTRITEYFEHRYQGKFFDEEMILGELSEKLREDVINFNCRALVASVPFFANADARFVTDVVTKLRYEVYQPGDIIIKEGTIGNKMYFIQEGIVDIVMSNGEVATSLSDGSYFGEICLLTNARRTASVRAETYCNLFSLSVEHFNTVLDSYPLMRRTMESVAAERLNKIGKNPSIVSNREDLTNDCKTVNAIVNALASVAATEQGDGGTSSEESMMPADRSSLKSRRHHHHNLLDLGSIGQALAKGHLPRPKSENNFALSLDQPSPLNRNRPSFHKSDTFHKDTSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-03-27" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7G7</accession>
    <name>A0A423U7G7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000516">
        <property type="protein sequence ID" value="ROT84642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7G7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="657" mass="72255" checksum="DAB15EE76CA5D529" modified="2019-05-08" version="1">MTDICRKHSLSRWPPSCRTHSLIHSHVGRLPAASTLSHVGRLPAARTHSFTLTLAAFLPHALTLTQAAFLLHARTHSHVGRLPAARTHSLSRWPPSCHTHALTLTLVAFLPHAFTLTQAAFLPHARSHSHVGRLPASRTLSLSRSRLPASRTHSLSRWPPSAHASFTLTLAASCRTHSFTLTLAASCRTHSLSRRPPSCLTHALTLHVGRLPASRTLSLSRRRLPATRTHSLSRRPPSCLTHALTLTQAAFLPHHALTLTQAAFLPHALTLTQAAFLPHARTHSHVGRLLPHALISHRRLPATRTHSLSQQAAFLLHALTHSLHVGHLPASRTLSLSRWPPSCLTHSHSHAGRFLPHARTHSTWPPFLPHALIHSHLAAFLPHARTHSHAGRLPATRTHSLSRRPPSCRTHSLYAGRLPATRTHSLSRLPPSCRTHSLSHRPPSCHTHALTLTCRFLPHALTHSLSRRPPSCLTHALTLTLAAFLPHARTHSHVGRLPASRTHSLSRRPPSCLTHALTLTLATFLPHARTHSHVGRLPVSPTHSLSRWPPSCRTHSLTLTLAAFLPPARTHSLTHSRRSPSCLTHSFTLTLAAFLPHALTHSLSRRPPSCRTHALTHSHVGHLPAARTHSLSHVPYGSSLCRQNKRNEDLHVNTIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7N4</accession>
    <name>A0A423U7N4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Troponin C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000506">
        <property type="protein sequence ID" value="ROT84712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7N4"/>
    <dbReference type="STRING" id="6689.A0A423U7N4"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="97" mass="10890" checksum="FE8F6312B72ED24D" modified="2019-05-08" version="1" fragment="single">MDSLDEEQIETLRKAFDSFDTEKTGSITAETIATIMRMMGVKISEKNLQEAIAETDEDGSGLLEFRSSSSCRRKFLIEEDEEALKAELRGGFSLFTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBD8</accession>
    <name>A0A423UBD8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000036">
        <property type="protein sequence ID" value="ROT86032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBD8"/>
    <dbReference type="STRING" id="6689.A0A423UBD8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019054020" evidence="2">
        <location>
            <begin position="28"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT86032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="609" mass="69075" checksum="B27638F4F8F6F7AB" modified="2019-05-08" version="1">MHFFLLLLHPPWTLFFLTLRDLSNVFSTLVLYEADDAPPAEVVRDLVETLPHFLSHYFFLPFHIIFFPLPFPHFPSFSLTPPSTPSFRRLRTLPHFLSHYLSSSLPSFSTLFSLTPSTPSFFHLIFSHIIIFFSHFTLSFPPPLSSFPLFLPHSFFHALLHPPQDPPSFSPTLSFSLSSLLILPHSFFHPRTLPHFPSHFFLSFHIIFFPLPFPHFPSFSLTPSPSTPSLRHLRTPPSFSFTLSFSLSPFFIFLFLPHSFHALLHPPHFLSHYFFSSISHYLSPLSPSLISPLSPSLLLPRLPSGTSGLPLIFFHIIFLPLPFLHFSLSPSLPPSSTSFSLTLFFFLPFHIIFFPLPFPHFPSFSLTPSPSTPSLRHLRTPPHFLSHYLSPLSPFLISPLSPSLLLLPRPPSSTSFSLTLFFFSHFTLSFSLSPFLISPLSPSLLLPRPPSSTPRPSLIFSHIIFLTLLFAHSPSLFLPPQDSPSFSLTIFFSPISHYLSPLSPFLISPLSPSLLLPRLPSCTSGPPLIFFHIIFLPSPLSSFPLFLPHSFHALLHPPNFLSHYFFSPISHYLFPSPLSSFPLFLPHSFSFHALLQASQNQYDPISPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-12-20" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A292G5C4</accession>
    <name>A0A292G5C4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hyperglycemic hormone</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Sinus gland peptide C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002877</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-08" db="EMBL/GenBank/DDBJ databases">
            <title>Gene structure and expression analyses of multiple vitellogenesis-inhibiting hormones in the whiteleg shrimp Litopenaeus vannamei.</title>
            <authorList>
                <person name="Kang B.J."/>
                <person name="Sultana Z."/>
                <person name="Chen H.-Y."/>
                <person name="Zhang G."/>
                <person name="Wilder M.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.</text>
    </comment>
    <dbReference type="EMBL" id="LC318431">
        <property type="protein sequence ID" value="BBA57874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001387">
        <property type="protein sequence ID" value="ROT78399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A292G5C4"/>
    <dbReference type="OrthoDB" id="6365952at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2010.10">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018251">
        <property type="entry name" value="Crust_neurhormone_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031098">
        <property type="entry name" value="Crust_neurohorm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035957">
        <property type="entry name" value="Crust_neurohorm_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001166">
        <property type="entry name" value="Hyperglycemic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000346">
        <property type="entry name" value="Hyperglycemic1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981:SF2">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01147">
        <property type="entry name" value="Crust_neurohorm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00548">
        <property type="entry name" value="HYPRGLYCEMC1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00550">
        <property type="entry name" value="HYPRGLYCEMIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81778">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01250">
        <property type="entry name" value="CHH_MIH_GIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036035028" evidence="8">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="47"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR631098-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BBA57874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="114" mass="12891" checksum="F735D05D1B7A0F09" modified="2017-12-20" version="1">MTAFRMVWSMLLASLLLLLAASSAAPADALSAPAAGLTKRSLFDPSCTGVFDRQLLRRLRRVCDDCFNVFREPNVSTECRSNCYNNEVFRQCMEYLLPPHLHEEHRLAVQMVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LPK0</accession>
    <name>A0A3R7LPK0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endothelin-converting enzyme 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021305</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004450">
        <property type="protein sequence ID" value="ROT60976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LPK0"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF237">
        <property type="entry name" value="NEPRILYSIN-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="10">
        <location>
            <begin position="137"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="9">
        <location>
            <begin position="594"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT60976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="90597" checksum="503C30903E25E376" modified="2019-04-10" version="1">MEIMTGRENDVAETSGVLRRAWGRRTPLEKVLLAISGVAVLACMAMVGILATSGSQTPRTLSADMLPSQAKESQTRLTAEVIHDNFLKFMEVHDDKAHRLPVYNTQTASGKVEICSTEECVLAAADILEAMDTSVDPCDNFYQFACGGWEQKNPVPDESSRWSQFDLLRRELSNALSVILEEPEAADEPSPLKKAKVMFSACMNTTALEEAGLKYLTDFLSLYGGWPMTSTDWSEKNFDWQFTVADGRKTLGSAYLLSVWVFADQKDTDTTALYTDQTSLGLPRSVLINPSNYEERINAYKTYMAETASIMAKHLGQSVSSEDIQLDVNAVFDFEMLLANITTPDEDRRDIDRMYNPMTVAELSDLTPNTSINWQQLLSNMFAVTGNPIESTTRVIVQEVEYMKRMAILIDTTNQRTLANYLMWRHVKALGDETNQEMRDASFKYAMVANGVTAAEPRWKVCADKTNDFLGIALGTKYVETYFSQQAKDEANEMVEDIRSAFKDLLDVNDWMDEATKPLAMEKANAISKFIAYPDWYGNATALEHFYDDLGDVHTDRHFSNVLTLSSWWSTDELNDFGLPTERSKWFSAPTIVNAFYMPEFNSITFPAGILQPPFYRANSLQALNYGGIGQVIGHEITHGFDDQGRQNDKNGNAIPWWTNATLESFMVKAQCIVDQYDNIRVPEIDDFMPNATLNGVNTQGENIADNGGLREAFLAYQKYIDRNGEEPRLPGLDQYSPQQIFFLSNANIWCGSITKEGLLNQVLTDPHSPGKFRVLVPMQNMEEFSSVWSCPVGSSMNPEKKCIVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRJ9</accession>
    <name>A0A3R7LRJ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004418">
        <property type="protein sequence ID" value="ROT61025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRJ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="49183" checksum="F34D4B83322C45C2" modified="2019-04-10" version="1">MNKMKVPGPPPVIPRTSQFLEPIDEYDPNAFLSLLFRFSYSHLLSFFLSLFYFSPSFPLFFFVFFFLCFLSLLLFLLSFVFSFPLLLLSFFSYLLSFFLTLFSFFPFFFFLSSLSFSPSFLPFLFFLPFHPFLPFFPSFSHPCPAFFSYFFSLLSFFLSSLPFLPLSHPTLFLRGPSHPPFLLSFLLSFLPPFIYSFFLSFILPFLFFLLFISSSIPPFRLPFPHISLLPLLPPHDLFPTLFHQFLVVLLVPFMKLIFLIFIIFPSFFLHLILLLQLLLFLPFLLLHPPQLFSFLLFIFLSFSLPLPPLPPLPPPPSSSTFLLSSLHLSFLFSSSSSSSSPSSSSIFLNFSPFFSSSFLPFLFLFLLFLLFLLLICLFILSTTHRIPAYYTSMMLFLSINTNGLFIMAEQRGFGKNIIQTTNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LU31</accession>
    <name>A0A3R7LU31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003259">
        <property type="protein sequence ID" value="ROT64379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LU31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="50637" checksum="347D1EEB13FBF98E" modified="2019-04-10" version="1">MGRPHQPSEKGRKCRAFLAFGTLPDAPFTCPPHPTPPSSPRPSLPAPAPFPLLYPSLPVLCPLFSFLSLSLPILYSLSYYYPYLSFPPCPLLLLYYPYLSHSPSLSSILFTISLTLPPYPLLSFLFSYPYPSLLLLPVHYPLSYLYPCPSLPPFPMFSFLFLSLSLSLPVLYSLFYSYPSPFRSLSSISIYSYPSPSLSYNRFPTPLRFPSCNPSSFLSLSLSLVLYSLSYHSSPYPIPLSFFPVFLLFSIPAIIPSSSFHKPLLLLLFLLPPLLPSLHLPSPSTTLFSFATSSSLLTFSLSLSILPLPSRLTPLVPLAPLALLACPLSSISSSSLPSPDRLSMLLPVSCSPAFLSHALHLAFPSFFLSFLPFLPSFPSFPPPSLPPSFPSSLPLPLCPPQPISTAPPPHPLISAPLSFLPSLPPPPPSLPFHPSFLSHSFIHHTLPSYSPPPLFPPSAFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWJ3</accession>
    <name>A0A3R7LWJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015574</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002941">
        <property type="protein sequence ID" value="ROT66402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWJ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018684246" evidence="3">
        <location>
            <begin position="20"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="623"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="938"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="631"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1065" mass="119605" checksum="B36615D6E1ED7BD5" modified="2019-04-10" version="1">MSRQHTVLILNPFLLGSLGAKEKFTRVPVPVSGCLSTPWVIPLGPGLTHNTPRPALHHDNAAWQFSIPEESILRGGLGLGSPSPSPPKSFLTPPPALPSSGSSPPSPTFPLDPHHASFITLAVQQSFLPLLPLHLNSMQCHSTPFPPLHEISQPFPTIPQNPFTSSPSEIDFLLPHLESDLLRHSSSTLLRHLEFDLESDTSTSSVHLEFDLPPAVTSNVDAPPPYTSSLTSSVTSSSNLDPVTPEVHLLPPITSSHLDFRPSSRHLITSSSSHPQSDIVPSSDSDLHSSRHLEIDDIQPLSLTSIPSVTTQCCIDLLLRSSLTSFLRPLVSLLRPPSSVTSSPSSRLPPSPRFDLRHLEFDLLRHLEFDLRHLEFDLRDLLLLTSLLFHPSLPSSVTSSPSRSPRVSTSSVTSSFDLLLRHLGQTLPPSPGLRLLLRPCSTSSSVGLRLLRHLSTLLRPSLTLLPSPRVDLLLRHLNFDLLLRHLDFDLLLRQLESDLLLRHLEFDLLLRHLESDLLLRHLDFDLLLRHSSLTSSSVTWNFDLLTSDSSSVTSSSTSSSVTSSLTSSSVTWDLLRHLEFDLRSPRVDLLLRHLDSRPPPPFDLLLRHLDFDLHLPVTSSLTSSSVTWTSTPPPSPGLRPPPPSPLRPPPPSPGHLGLRPPPPSPWTSTFLLRHLGPPPPSPPPPSLEFDLLRHLELTSSSVTGLRPPPPSPRFDLLRHLETSSVTWTFDLLRHLEFDDLRRQDPRSSVNWTSSHLEFDSSSATSKFDLLLRHLEFDLLLRHLEFDLLLRHLEFDLLLRHLDFDLLLRHLESDLLLRHLDFDLLLRHLESDLFSVTWTSTSSVTSSSTSSSRHLEFDLLLLDLLLRHLDFDLLRHLEFDLLLRHLEFRLLLRHLEFDLLRHLELTSSSVNWTFDLLRHLEFDLLRHLELTSSSVTWTSTSSVTSSSTSSVTSSSTSSSVTSSLTSSHLEFDLLLRHSSSTSSLRHLDSTSSSRHLVLTLLLRHLDFDLLLRHLEFDLLLRHLEFDLLLRHLESDLLLRHLEFDLLLRHSSLTSSPSPRVDLSPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1Z6</accession>
    <name>A0A3R7M1Z6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">alanine transaminase</fullName>
            <ecNumber evidence="8">2.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010968</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-alanine + 2-oxoglutarate = pyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:19453"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="2.6.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-alanine degradation via transaminase pathway; pyruvate from L-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.2" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01002392">
        <property type="protein sequence ID" value="ROT70730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1Z6"/>
    <dbReference type="STRING" id="6689.A0A3R7M1Z6"/>
    <dbReference type="OrthoDB" id="1732682at2759"/>
    <dbReference type="UniPathway" id="UPA00528">
        <property type="reaction ID" value="UER00586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004021">
        <property type="term" value="F:L-alanine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000140">
        <property type="entry name" value="alanine aminotransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000236">
        <property type="entry name" value="Alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="10">
        <location>
            <begin position="20"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT70730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="341" mass="38031" checksum="E1AB8B8EB7E7642D" modified="2019-04-10" version="1">MQGGSLVPTVTLLALRSSDHVAEYIERRDGFPSCWENIVLCAGASEGIRGTMKLMINHENGVKPGVMIPIPQYPLYSATIAEFDLHQIGYYLDESKNWSLDLAELKRAYDDAKSVCTPKALCVINPGNPTGNVLTRENIEGIIKFAHERNLFLFADEVYQDNVYAEGSKFHSFKKVLMEMGEPYNKMELASFMSCSKAVKAMYLKSISAKLCPTTLGQAVMECVVNPPKEGEPSYESFMKEKQGVLSSLATRAKMVADTFNSITLPEKAIEAAKKEGQAADVFYAFQLLENTGICIVPGSGFGQRPGTYHFRTTILPQPDKLKVMLEKFREFHSNFLKLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M211</accession>
    <name>A0A3R7M211_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Crustocalcin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003145">
        <property type="protein sequence ID" value="ROT65094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M211"/>
    <dbReference type="OrthoDB" id="6373350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018703192" evidence="3">
        <location>
            <begin position="21"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="777" mass="81111" checksum="2286C9E6083A0D7E" modified="2019-04-10" version="1">MLIHPFPQVLVVAAVVGVAARTIFDYERDGLENEQKGQPGQAVTGEYEWRAPDGKVVEISYVADHLGFRLVDDPEPTATHESSGKEKSEEPEEGAEAEEKSAEPEAEEAEAEGQEPEAAEAEQGKADAEAEENAGAEGAAKKASEESATADEVEAESEAAGAEAEVAEAGGEPAGKQLSSGTPVLVPVKVESNFDSVSLATEAPVIATAEMLPPVAPLVAPMTVEAPAAPVPSAEVSFDAAHSASANLVPQDLVLFVIPPVEQFVTVPDVSQPAPATAPFASAASALPLEIPQPAFTDSDLVLTEQGSEEPVLLLPELPLALVASPEGTNVVLEKPVFEKVEVSAPIGVPEIDSDIAVIAKSYDSVQAAPQFLATDLSGSFDPVADIPASLSVIPASDTAFVPVENIPKMIRFEEVVEVSPEVALAPELPSPLPLIQLDEVDPSFVSVEIPAAPLPQPDTKPSSLFGADVEVLPEPQFIAPIVPPPSPLSQDDAPFALPPHRFEAPKSGRSMDSVPVFVESSHAEPINALFFVPEALQEESKGLSLETIEIVVPEDSIMTVAKSLVQPPTMPAEPVVYRETEVETVEPLLTQLEFGPAPSPTGAEASQAQGSVSFANSIPLSLKDEILFSAADASPLTLDASPVEITFVEVPAEDPFPALPEAIAQPLTGMQPGAQSAFEEPVLLDVSATAEVQVPEVSAPTVAIFETDAGPEPVFEEVVMISEEPAGAGPRTKVTIITDDAPSDPLDYDDATVLVSKSVQSPPLLPPLMKPSVILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6B6</accession>
    <name>A0A3R7M6B6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative MLX-interacting protein isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001927">
        <property type="protein sequence ID" value="ROT74164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6B6"/>
    <dbReference type="STRING" id="6689.A0A3R7M6B6"/>
    <dbReference type="OrthoDB" id="6022628at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11405">
        <property type="entry name" value="bHLHzip_MLXIP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF37">
        <property type="entry name" value="LD38259P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="610"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="155"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="654"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="216"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="268"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="363"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="816" mass="89102" checksum="9B47E02BE34E419C" modified="2019-04-10" version="1">MTKQNDQAIVLEGKYWKRQLDAVTAEYKKWRIYYKNKISGKNILDSDASIFDLDGMDFSRGSGMQVSLDDGDLSEFMDFTSVLFSSLISPSQAFAFPNPREIARGTGNSDFIQPGLIQLQPNLDDFMDIVEPLQEMLAGRGLATVPEEDFLPEVGETPELPAASSPPVSLPLHYNTRPHPPSWSPRPPHPPPHSPSHKAIAPLPQQHPSSVFSAGQIPLQQQQQHQQTSIKSPQQQHQQKEPQLVPIPTQSPPTSYQASLGIAPVPAQTQHLQPQQQSPNSSLQLQQPPTPPQQQLQQLQQPLTPPQQQLQQPLSPQLQSQQCPRSFIRSHSQHDLSTPPQPISLGDSSFVVPSAVPRRRSHSSGGSNSSSGLVGSPSLAPHQVISSVPVTSLPHLLPALNSMTATSLSHVAPTAPPTASVQASGTSLVTAPVIAPSSSPAGSALLAQLLTSGSYSVSCNSQPINTNQLATISSTNQLNNLGNNKSCNNVKVSLVIPGVITGNSSNSSCSSSSSSSSSLCSINSVTNIKPSVSTPLLMPPITLSAVTPSTLKTQSFSQLSPWSPCSPQGIIKQSPPHPEPSSPLMMNVPSPPTKAFRPKSDVERVQYKEHRRVCHINAEQKRRSNLKNNFDIMHQLIPSISQNHNAKISKAAMLQKGAEYIQQLKAERQQLSDQAEKFRAQIESLSLEISNAQSLLPATGAPMTHARHSKLKEMFNNYVRERTLANWKFWIFSLITEPLLESYNNSVSINSLDDLCRSSLAWLDQQCSLNVLRPLVSNSMRKLSTTTNVLAEPENLPEEIYRRVTKQEGERYPTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD98</accession>
    <name>A0A3R7MD98_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Disks large-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001233">
        <property type="protein sequence ID" value="ROT79516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD98"/>
    <dbReference type="STRING" id="6689.A0A3R7MD98"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098978">
        <property type="term" value="C:glutamatergic synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099572">
        <property type="term" value="C:postsynaptic specialization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023052">
        <property type="term" value="P:signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005026">
        <property type="entry name" value="SAPAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12353">
        <property type="entry name" value="DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12353:SF31">
        <property type="entry name" value="LD44824P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03359">
        <property type="entry name" value="GKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="23667" checksum="CE57624B74C9A523" modified="2019-04-10" version="1">MRPEWKLFDSRTKISPQATAAKIKELKEELARFKAEFPHPPTDTEVGHTPAKLEKDGHYFLKVVEEVVSSIEAEVLNTEQELELHGSEMTEEIRGKVLAAIGKARLLVSQKIQQFRGLCHKNIAGSEGEEFPTTSEDLAGFWDMVSIQVDDIKNSLQEIAKLKANGWKELSWADTVDGSGKNVMTGQAQKKPAPRPARAAKSTKSNTLGSARTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDQ7</accession>
    <name>A0A3R7MDQ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDQ7"/>
    <dbReference type="OrthoDB" id="2019940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="43233" checksum="5DF24611FDC5BCE1" modified="2019-04-10" version="1">MRLTSDRARARILPSPPLPPKAPTPAMRVLPATRRALALALAAAACVSFSQLCIFSASQTHSRFRSVTSEGEFIGATFDPRQASAGRKGNPQWKRASGNPLSYAESRQARKGFWNRSATRRTGKGGRFSTAATEGEVAREEKRRGPKEQKDREPRQTEGGLPRLSLSSGAALRDTDFAKYSPERICKSVRDKDSFPVSYHVKDLKAMGCPGKICTQGYAVRRSRLAFSPAPDARHMFLPLFAPQDRLILESRVGVMAERARAVARACQETPPIEGTPVRENFIWDLRHKPSIVWCPTYKVASTTWMRNFLLLGRFNEHNPRIPRNLSAEERERRRFKPKYGATHGAAFAMYGRPPTAAARARALRESVRLIIVRHPFTRCVPEALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGE9</accession>
    <name>A0A3R7MGE9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative sodium-and chloride-dependent GABA transporter 1-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021134</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004339">
        <property type="protein sequence ID" value="ROT61127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGE9"/>
    <dbReference type="STRING" id="6689.A0A3R7MGE9"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005283">
        <property type="term" value="F:amino acid:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089718">
        <property type="term" value="P:amino acid import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF241">
        <property type="entry name" value="SODIUM- AND CHLORIDE-DEPENDENT GLYCINE TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT61127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="49885" checksum="C1934F165697F14A" modified="2019-04-10" version="1">MQRRCTVLFHPGESGSRKVLHISSGLDDISRVQWQIVAVTFLTTAFLFFCVFKGVRVMGKVVWFTAPFPFAMLLVLLARGISLPGAVDGIRFYIYPEFERLKEMKVWAAAAMQIFYSLGPGWGSLISFGSYNMFHNRSTRDAVTVPVLNCTASILAGFVVFSVLGFMAKRAGVSVEDLTVAGPSLVFIVYPEAVSMMPVAPLWSVIFFLMLFFLGVDSCFAYLETSVICLLDEFPKLRERRGWVTFVICLISFSVTILFATDAGMYWITLMDWYCASFAVIVVCFCQICIFSYIYGAGRIIQDFQLMTKRPISYVWWVIWLAVTPPVLLCILANTVLSLSGAEYQGQTFPTWAQDVGWVIAFSYIPPIPAYFLYYFCCRTAGSFTQRIAACLSPSPAWGPAEDRHRQEWTQHRLKHPLRHRLLHPGLCAAEPSTSPDELLNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGI2</accession>
    <name>A0A3R7MGI2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative C-terminal pdz ligand of neuronal nitric oxide synthase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004288">
        <property type="protein sequence ID" value="ROT61219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGI2"/>
    <dbReference type="STRING" id="6689.A0A3R7MGI2"/>
    <dbReference type="OrthoDB" id="6372634at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="43606" checksum="F0A627DA085149E1" modified="2019-04-10" version="1" fragment="single">MSFLRQSVGETYASPLSEPLPSGDTLPQAGTPLSVHHELQLMREQLEQQQQQTQAAVAQVHLLRDQLAAETAARLEAQAARTHQLLVHNKELLEHIQALVLQVRDLEVKLSGQQSATMPSTQLLPTPPELKAQVVGRLTASVEANSAERRPPPRAGGLVTPRGLHGSVVSFVCRSMLLVPGASPGHTSQLAAALDLGGAAPLFRPPEPPPTPSPGLAQQSFLFPSPTSPTNSAPSLLGTLQLPILAQDPSSAPHSREPSPRVPSQGPLIHPLPVWATEGGRGGEVTLAVPRQDPLSAPKLQGLPRPRGAQRYEDCSSTPSLSSESDPKRDSSGQSSGESVTQAVAQLYALEPQRLAQVPEDAVTLGPYGPTPLGTPRNLNGPITRTASERVSRQETLAQLQRMAWARHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIV6</accession>
    <name>A0A3R7MIV6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative class B secretin-like G-protein coupled receptor GPRmth1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 2 family. Mth subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000763">
        <property type="protein sequence ID" value="ROT82885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIV6"/>
    <dbReference type="OrthoDB" id="6134459at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15039">
        <property type="entry name" value="7tmB3_Methuselah-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052808">
        <property type="entry name" value="GPCR_Mth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036272">
        <property type="entry name" value="Methuselah_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46953:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR MTH-LIKE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63877">
        <property type="entry name" value="Methuselah ectodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="573" mass="63836" checksum="5A5CFD381840CADE" modified="2019-04-10" version="1">MNLISVRANTRARAHRNTQNPSAESDAVPGARLVANVKQQFWSCRRRGLCERCCSRKAKDSCPLLPASPSERMFLLRLGLLLPALTLGTTHASGASGRRCCEEGKGCAGGGIVDVFEPPVSPSLDVSWSFHPLQCPEGYRKHQVDIEEDSLVPRQASLELRWMDVFWRRTTEFCVAVNFTGKYIAFLCRPDVQKVCKTKHCVQMCCAEGNFLRDRECVRSESPPGTQADDVHFVVSTPKCDSSSQFLTARDFIDGENEFNVSGDGALSFPSDDDSYEIGRYCLARNENGTTDRAIYCARQLSELLQQKNQAVKICLIVSCVFLALTILNHGLTKKLRDVQGLCFLFHMMSLLVADAALICSTWFSKHISLTHCIINGFILQYSFLATFAWINVMCFDIWRVVKATVSLVPLSDILASDAKKFRIYCALAFGLPLAIVAVTVVLQVLPTNLLPENSFFRPNLGTGSVCTCCSKKAPVTAFNRNHLEAFWQRFSLFCVSVLCWVTEFLSFLIQAPEIWIVTDIINSLQGVIVFFIFITSKKKRRIVFQSWESTVSSVVSRASKTFSRSDSAGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ06</accession>
    <name>A0A3R7MJ06_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003512">
        <property type="protein sequence ID" value="ROT62972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ06"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="216" mass="24842" checksum="D917181CF2157C0A" modified="2019-04-10" version="1">MLEKRMNSRWASSPLSRLLPFVGAGRVQIESFLGYWDRRFSCCAAARSSTLWNGRTRPGTTLQVRPGPRARPQRRLRRRRRPRQAPPTMPNWSLLDALYGPRHETHAGGNKMTHDEGHETRHDEGHKKHGEGHKKYDEGHKTTHDEGHKTTRDEGHDRRHRPKANSDLVIRIPKTEASDLIVQILHGLDRIRRRGPYRHSVEGGLPARSGRGRRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLA0</accession>
    <name>A0A3R7MLA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative phosphatidylinositol N-acetylglucosaminyltransferase subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022132</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000513">
        <property type="protein sequence ID" value="ROT84678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLA0"/>
    <dbReference type="STRING" id="6689.A0A3R7MLA0"/>
    <dbReference type="OrthoDB" id="196709at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009450">
        <property type="entry name" value="Plno_GlcNAc_GPI2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06432">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016104">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="271" mass="29694" checksum="7D5D5A38D14A19CC" modified="2019-04-10" version="1">MTEWSRVLWKKQPYPDNYVGDSFLRVSKKRREVTYGQAFYSATAVTQEICSCLILVAVFCGLSEGHMKAAGVLTFTAVLGVTGYFITRSQLRSSARDDIKLVCFYVALISCASPVVKSLTGSVATDTINACTTALLLLRIVHQDYGALVAIVNPTVSHNLGVFASVCLASRLGSDRDVFALMTLAVALFALFPGFRKYCRTKLGTTLDLFFTIVVVTVTAAGLWLYAIHLMPLLAFALVTCNGIIPALFVALQRHKQNIYGPWDEAQIEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLB0</accession>
    <name>A0A3R7MLB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative roundabout-like 2-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_005391</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000170">
        <property type="protein sequence ID" value="ROT85843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLB0"/>
    <dbReference type="STRING" id="6689.A0A3R7MLB0"/>
    <dbReference type="OrthoDB" id="428111at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008046">
        <property type="term" value="F:axon guidance receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050808">
        <property type="term" value="P:synapse organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF15">
        <property type="entry name" value="NEURAL CELL ADHESION MOLECULE L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00406">
        <property type="entry name" value="IGv"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="856"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="56"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="170"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="261"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="349"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="449"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="561"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="7">
        <location>
            <begin position="741"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1022" mass="110052" checksum="6E4814B6C7586519" modified="2019-04-10" version="1">MFDDDSFEKWSEAKAWSEGPEAETHSCETSSAAEASLSPCGLRLRPVGLEGGAGPPVIKEHPSSVAARRNDPATLNCAASGASRIRWYRDGEEVTTAAEDPRSHRVLLPSGSLFFLRVATSKRDSDAGTYWCVASNSHGATRSHNATLTVATLAYDFQSQADPVVRARVGDSVVLPCRPPKGSPPPEVTWLRDSHEVTNSSRISVSQAGDLVISQAVEEDSASYVCRARNAAGARESTPTKLTIMTFVLSPNGALSPAAPPWFEERPANVTVASGVVVELACRARGSPTPTVTWRRLDGKMPLGRAMIEDQRLVLDHVAAADSGVYVCEVESEAGIAAARATLTVIDAPEFAQRPQDVQVVAGQSARLSCKVEGDPKPLLLWRLPTQDRTALLAAGQSSGHASVADQGQTLLLGDVTTLETGTYSCWGVSRGGGISAHSEVVVVKAYPPPVIGIGPQDLKVSPGVSVVFPCEAVSEAAQASVSWWHQPAASHPIRHLSKGSKSGRVSILVNGALVIRDVRVSDAGTYRCHVSAETGSIKRSAVLQVVEAAEEYRPFLLPAPPSKPRLMAVNQTAVHLSWLPNSQMGGGSDQTYTVEFWRQGWEEWRVADALISQESCVVGGLTPGHTYTFLVRAVDSRGASFPSPWSDPVTTRSPRDPSLTEDEFLALADEAVEGVLVYAISDSGVVQVVTVLGSSTSHPVHGLQANTPYTFFLVPFWRSVEGTPSNSYSLQTPQDAPSVAPTDVRVTPLEEGSVLITWSTLEPEKARGEIVGYQVIISHNTTYTSETVVNPWLDAIGLVPGQLYTIRVSAVTKAGPGPFTAPLLVDIGPSQVDSQPREESDIASTDFHAPERPQWLIVLHIITPIVLLMSLATLLYVRKLNDKPVTSTAPKSSLLYQVPECLFSSRLPESASTYSENMILAPSKSQFSSASSSPLLRYHERVNEYAEPRFQKPNENTEPYATTTLLVPASPCPNHPKHWSRNTEKTSTSTYHWSVSLPSSHASSFTPHSMDYHCSSVRYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLE5</accession>
    <name>A0A3R7MLE5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003199">
        <property type="protein sequence ID" value="ROT64743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLE5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="477"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="508"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="551" mass="61948" checksum="B6ADD8413B560B93" modified="2019-04-10" version="1">MQRKHERQRLTANSNKNKNWSPPYLGRSGAKAALPSPFPPAVIRLFQFLFLGLSFYLSSFFSPSFSTISLLSLFLFLAFFLGHLSVTVSLLRSLLLLLFLFLSIFQGHTPMTVSLLWSLLLSLFLFVSVFLDHSSVTISLFWSLLPSLFFLSLCLNYFLPSSLPCFHFSPSVCYSIFLLSLLPSVVFPPSYIPLSSFFSFVPLFFLYFSFLASFITLSSFLSIVLLFCLFSSLFPSLYDIPSLLHDLIFTFLHHSSLPLLLFLSFFLSLPLSFPPFISILSYPSLFHSSSSFSLSLLPTPFLLPSFLFSLSLPLLQSLLLHLLPLILLFLFTFTFYHLPYSPIPPFLLPSSHSSPSLSHSFTPFINFPSLFRFQPFLPFSPSPSSTISRIPSLLFLFLPPLFTSPLLLLPFLPSLLPLSFSLPTFFTSPLLLIPFPPYLLYFPSPSPSLPSLLPLSSFPSLLPLSSFPSLLPLSFSLPSLLPLSFSFHFLPSLLYFPSLTSYSSLPSLLPLSFSFPFLPILSLCLPFASFPPIFLSSRMPLCEILLNTTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMM7</accession>
    <name>A0A3R7MMM7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">p53 and DNA damage-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016418</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003066">
        <property type="protein sequence ID" value="ROT65615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMM7"/>
    <dbReference type="STRING" id="6689.A0A3R7MMM7"/>
    <dbReference type="OrthoDB" id="20282at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22860">
        <property type="entry name" value="PDRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030482">
        <property type="entry name" value="PDRG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21162">
        <property type="entry name" value="P53 AND DNA DAMAGE-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21162:SF0">
        <property type="entry name" value="P53 AND DNA DAMAGE-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="77"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="15507" checksum="5F0CB27C9A1F9FEC" modified="2019-04-10" version="1">MAVSPERIQQQLEEVEAAAEDVISDRQEIVTLDRRRNTNREALRQLKTNKIASQSTGNKSWICVGNMFLKLPNTVVVDCIEKEQKQLDTEINNLRNGLRSKVNHLNDLEAKQKTVGTNLKPLSQDEWKAVKQVLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPY2</accession>
    <name>A0A3R7MPY2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">DNA repair protein REV1</fullName>
            <ecNumber evidence="13">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_024032</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01000775">
        <property type="protein sequence ID" value="ROT82788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPY2"/>
    <dbReference type="STRING" id="6689.A0A3R7MPY2"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17719">
        <property type="entry name" value="BRCT_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01701">
        <property type="entry name" value="PolY_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000001">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000011">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053848">
        <property type="entry name" value="IMS_HHH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012112">
        <property type="entry name" value="REV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21999">
        <property type="entry name" value="IMS_HHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036573">
        <property type="entry name" value="REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 13" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="16">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="UmuC" evidence="17">
        <location>
            <begin position="284"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="174"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="746"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="853"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="939"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="760"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="800"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="853"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="879"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="896"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="971"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="997"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="1024"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR036573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR036573-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT82788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1121" mass="123352" checksum="7594E7FAA27554F9" modified="2019-04-10" version="1">MAAKIAKLEKQYESSTSNINDNSQGIFRGIAIFVNGYTEPTGEELKRIMMVNGGTYHHYYSRSKTTHIIASNLPDTKVKNMNTERIVNPKWITDSLRAGHVLDYTKYLLYTNQSGSQPKLPFKPLSVDKNEKMRLDTSSSVSSDIAVDHKMQSSVEMHEASSNDLKLNITDTSNLTADNSGDKTNLDTTKNQTTGESPTKGHAMSTANPKFLSEFYNNSRLHHISTMGAIFKQYVNEIKRKGSSFPGRKRLMEWLKTSTKNTIKPEGSHHHLDKGFKLRSKRVIMHIDMDCFFVSVGLRKHPHLRGIPVAVTHAKGNAPTQAREGRDRQYELNYYKERAEKKLMKKMKPTNQAPLVNKETFDISDEESVEEPAKSTTPSSDKKFSSIPLIDETSSMSEIASCSYEARKAGVRNGMFLGPALKLCPSLQTIPYDFEGYKEVSYKLYDIVASFTHDIEAVSCDEMFVDLTELLNSCQASPEDFASLLRSEIQAATGCPCSAGMGPNMLIARMATRLAKPNGQHLAIPDDFADYMKDHKVSELPGVGWSLGKRLESEGVRTCKDMQAWSLGQLQTAFGSRTGQSLYNYCRGIDDRPVKSEHMRKSVSAEVNYGIRFTCVADAEKFISELAAEVANRLTSVNLKGKCITLKLKVRAKDAPVETAKFMGHGVCDNVAKSVSLSSATCSSDKIERETLSLLRQVKAPPQDFRGVGIQVSRLEGHQGSSGSSSSNKSVKSFFLAAKTSSKKSIFSQDTAEKKERLDNSISSSNTVSNVSNLRRSESYLDPQPGPSGLQRTDPKESKSSSGVNHTSGSKNQSTGKGTVDLDVLMALPENLRNQVISEYEQQGYTIPCAAKSPEKVSRTVGSDRESSLSLSSKMASPGDKDVTGTSEDRKDTYSPHRTSTNSESLESEDLITSFSQVDSSFLDAIPAELREELRQDFEHKKQAEASRSASSGTKNKDTFLVPVMQAPVKKGNKPKEKRGRPGKLDPRRTANKGLTKLTSLLQGPNNKLSSKIDDDFQPPIAMKKPKGKSVKTQNKKGSPKGSPKKVKPLQSALPVKDVQQLCHPVPFNPRAPCALPLGQLPSAHSQDLVMPYVLPQSAIPLSLNEMPSISSSLGQESLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MU83</accession>
    <name>A0A3R7MU83_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Homeobox protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_011931</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paired homeobox family. Bicoid subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002513">
        <property type="protein sequence ID" value="ROT69838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MU83"/>
    <dbReference type="STRING" id="6689.A0A3R7MU83"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000679">
        <property type="entry name" value="Homeobox protein aristaless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003654">
        <property type="entry name" value="OAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45882">
        <property type="entry name" value="PITUITARY HOMEOBOX HOMOLOG PTX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45882:SF3">
        <property type="entry name" value="PITUITARY HOMEOBOX HOMOLOG PTX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03826">
        <property type="entry name" value="OAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50803">
        <property type="entry name" value="OAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="85"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="OAR" evidence="11">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="61"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36046" checksum="D994DF0F72481C08" modified="2019-04-10" version="1">MYKRSCSTESDDSSSIESPLLSIFHSHSSFIQSPPLPLFPISPPSIHPFLPLSNVYFSPSPLTDAGEKPSQSCSTESDDDKNKKKRQRRQRTHFTSQQLQELEATFARNRYPDLSAREEIALWLNLKEAQVRIWFKNRRAKWRKRERHAMATAMPGDLKGGWGAQLNGLAWPDEGLYSGYSSYNNWAKVTPPPLGAKSFAWGFNGVNMNPLMSQQPSAMSPINCFQTPTQGMGGSANLMPTSMSSSLGSSAAPCPYPAPTPPYVYRDQTSSMSSSIASLRLKAKSHSPAFSYSSGGADTRSPPVPDNNAFFAAAAAPSDKFSCMNTVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MWX9</accession>
    <name>A0A3R7MWX9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_010079</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002276">
        <property type="protein sequence ID" value="ROT71592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MWX9"/>
    <dbReference type="STRING" id="6689.A0A3R7MWX9"/>
    <dbReference type="OrthoDB" id="2516at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000004">
        <property type="entry name" value="Putative diphthine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="9">
        <location>
            <begin position="3"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="9">
        <location>
            <begin position="276"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT71592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="544" mass="60212" checksum="1EEBCA8CB0FD084F" modified="2019-04-10" version="1">MVFYLIGLGLGDPSDVTVRGLEVIKKCARVYLEAYTSIISGGKEGLEKFYGREVILADREQVEQASDDLFAGAETGDVALLVVISNASIMNAVGCCGLQLYHFGETVSIPFWQDGWEPVSFFDKINRNLKKKLHTLCLLDIKVKEQSLENLLRGRKIFEPPHYMRVHQAAQQLLTILQRHSSNPATSGKDPVGEDEMQLTENTQCVGIVRVGTSSQRIMRGTLKELAESDLGEPLHSLIICGECHPIEEDAMSKLAAYFNGQQTEPRNSTSKRGVFHLIGLGLGQPGDVTVKGLDIIKKCSRVFLEGYTSIMEGGVEALQELFGREIQVSDREQVEQQSDGILQCTHEGDVAFLVVGDPFGATTHADLVIRALDENIPVNIVHNASILNAVGCCGLQLYSFGETVSLPFWDDTWRPDSYYDKICSNMENGWHTLCLLDIKVKEQSVENLIKGRKVYEPPRYMTVAQAAIQLLEIIKMRAEQGKATPVTPDQLVIGLARVGTPTQQLKTCTLEDMAKVDLGGPLHSLVIVGETHPMEDEYVDMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MXW1</accession>
    <name>A0A3R7MXW1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1</fullName>
            <ecNumber evidence="6">2.4.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Core 1 O-glycan T-synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Core 1 beta1,3-galactosyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">C7M84_009325</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="25 26" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002180">
        <property type="protein sequence ID" value="ROT72304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MXW1"/>
    <dbReference type="STRING" id="6689.A0A3R7MXW1"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000017">
        <property type="entry name" value="Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="23" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 25" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="17" id="KW-0464">Manganese</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 25" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="24">
        <location>
            <begin position="55"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="23">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00040898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00041226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00042009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00043065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00059245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ROT72304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="311" mass="35831" checksum="A0CFCF7EB2074FA7" modified="2019-04-10" version="1">MAVVQVEELHRVKKETEDSQDLEAAIQLLKEQREAKALYEEVRVLCWVPVSPGLHNKTAVHVKATWGKRCNKLLFISTKDDASISAVDVGSEEGFKALWNKTRSALKYFYANFFNDYEWFLKADDNTYVVLENLRYMLRAYDTNDPVYFGHHYKSKGGYNSGGAGYVLGRETLRRFVEKALPNEAICTSRRYGEDFQLGQCLQAVGVAIVDTRDHLKQGRFFQQHVREILQNPNIHSHLVYYPVKKDGTPDSCCSDTVISFHQMSIADLYMLDYLIYKVRVFGYIQPLPLRVPLPPDLQGVPNRTLQKYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N423</accession>
    <name>A0A3R7N423_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001616">
        <property type="protein sequence ID" value="ROT76728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N423"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="256" mass="27922" checksum="9C840BDD7A73303D" modified="2019-04-10" version="1">MAVLCSSCGSGKVSSRSSLAADALSAVSRTVSSRATMKILIAMMATAMLAGPIYSQNWEVIMKNKRTNPLLAVLSGFSRRVASSNKGPFLRKMYCKSPITRTRRTERYAEPPLFALEDMALRHSRAKLSTSRLRGITWYRTWFRDRPFTSRTSSCLTCTSTTPKSTLATLMARGNPKGWRKRPMVPVAGPSGVPQAPQHALSGCLHALLYSQSDAISSSCKVEEGTLLALHNALVLLKALRKVARRCGVHDEASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N6V8</accession>
    <name>A0A3R7N6V8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001328">
        <property type="protein sequence ID" value="ROT78811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N6V8"/>
    <dbReference type="STRING" id="6689.A0A3R7N6V8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="463" mass="51188" checksum="265E8BEA2B0F8129" modified="2019-04-10" version="1">MVEDRRREDRLKVGKVEEGKMQGGKGRGRKGGRWKKWREERWKEEIRKTSNTFLSVAPTLPPQSPTFLSFPFAPSLPPNLQHFSPSFSPYRSPFNLQHFSLLPLFPPISNISFPPFSPSLSSISNISLPPFLPISPIAPPSISNISLPPFLLNLQHFSPSFSPYRILISRLNLQHFSPSLSPHRSPLNLQHFSPSLSPHPSPLTADTPTIISLSFPFSLKLPLNLQHFSPLLSPAPKFLSFLSNLQILSLSHSKSPTFLFSLAPSPSPSISNSPTFFSPPYLPDASPPIFQHFALLQPPTFLSTRFLSLQYFSPSLPPSRPTLPLNLQHFSPSLPSFRPDASVSISNIYLPLSLPSPSISNVSLPPFPLNLQHFSPSLPPQSPTFLSLPSPILTSSSFPLISNILSPSHLQHSLPPFAINLQHISPSLPLNLQHFLLPSPSISNISLPPFAINLQHISPSLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7S0</accession>
    <name>A0A3R7N7S0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001787</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family. NFIL3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001234">
        <property type="protein sequence ID" value="ROT79489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7S0"/>
    <dbReference type="STRING" id="6689.A0A3R7N7S0"/>
    <dbReference type="OrthoDB" id="6022300at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14695">
        <property type="entry name" value="bZIP_HLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000025">
        <property type="entry name" value="nuclear factor interleukin-3-regulated protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040223">
        <property type="entry name" value="PAR_bZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11988">
        <property type="entry name" value="THYROTROPH EMBRYONIC FACTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11988:SF56">
        <property type="entry name" value="TRANSCRIPTION FACTOR CES-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="126"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="20340" checksum="84DCA0012AD68BFA" modified="2019-04-10" version="1">MGWLAARRGLRGGGSLGGGSGPGSLGGARGAMPGGMGGAQGEAVLNAESNEAYSRFRDQMLAQVTSAKARRSQASRTSSQGSGDARLADTAAEAHMDPSQEVWGRAGGQGEGRRVRRRGHAELHVDEAYWERRRKNNEAAKRSRDARRAKEDEIAIRAAFLEQENLKLRVEVASLKSETAKLRCMLYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NT20</accession>
    <name>A0A3R7NT20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003012">
        <property type="protein sequence ID" value="ROT65959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NT20"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21071" checksum="52C50A27F16844D0" modified="2019-04-10" version="1">MTDRTALVSRLTRWRVTPARWDAASPAVDLYDLLPGCQRPRGCSRRGQSESLSLLAGWCQNGGHNKPVGSDLAARRGERCAPRTCSAGNGGREVANATRAPARPRRAPGGQSARAGARTSGRAGCAGLTVPSSPWHCVRARRDLHARHRHGTYHHPRAHTTHRPIVQGSSACPRQYAATLKGSFRADLAGRSCDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P183</accession>
    <name>A0A3R7P183_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_008980</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P183"/>
    <dbReference type="STRING" id="6689.A0A3R7P183"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT72619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="44800" checksum="8448E759BCD80771" modified="2019-04-10" version="1">MDDTLDAMAGARWFSTLDLKSGYHQVEMAREDKAKTVSFGQGLWQFTVMPFGLCNAPSCFERLMERVLEGLQWRTALVYLDDIIVFGGSFDEELERLEVVLRRLRAANLKLSPKKCLFFQSEVPFLGNIVGRDGVKTDPQKVAAVQDWPVPTCVADVKSLSASPYLLDTDASAEGLGAVLSQVKDGKECVVAYYSAKFTDPEKNYCVTRKELLAIVKSTEHFHPYLYGAKFLIRTDHAALQWLKTLKAPEGQLARWLGRLEQYHYEVQHRPGRVHNNADSLSRRPCEPECQHCLRREERVACRQLQVWGDSVDAEERWRQVQREDDDLTPLIKWMEASPERPGWPQVTAESPVTKHLWQQWAMLRLENGVLQRAGMMLVDGQVTGWCWCLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P2S3</accession>
    <name>A0A3R7P2S3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001983">
        <property type="protein sequence ID" value="ROT73835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P2S3"/>
    <dbReference type="STRING" id="6689.A0A3R7P2S3"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="272" mass="28613" checksum="EBCE7AAAFAEBCB78" modified="2019-04-10" version="1">MYLSIPLYPLVARHTHWLTCGADYELEEIRNLKASGVWPAQYTLSLILKTDWLFFFSFLSNVLDLVWSLGALPDGIQAAAYAAYAGRGYASYPSFGFPYPAGLTAAIPIRNESQGSSKGLTSNSVAPIRAVHVLAPGFPAGCGYFPSATGASITGVSPQTPTPADGFKAAAYYESGAVATPTLTPTAPITPTLTGDVTEDMLHYHLQAERLAAAGTYYDSGALAAVTMSGSGGDQRAQQSIQVTAAAPGAPHTRADHINSSPMLRTTEVFCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3U6</accession>
    <name>A0A3R7P3U6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001857">
        <property type="protein sequence ID" value="ROT74694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3U6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="56958" checksum="4339B9F84AACEEC6" modified="2019-04-10" version="1" fragment="single">TAEAARVAEARRRAASESRQGAKTCPSASGVKPEVWRKAAVTAEAARVAEARRRAASESRQGAKTCPSASGVKPEVWRKAAVTAEAARVAEARRRQPVRAGREPRPCPSASGVKPEVWRKAAVTAEAARVAEARRRAASESRQGAKTECPSASGVKPEVWRKAAVTAEAARVAEARRRAASESRQGAKTECPSASGVKPESRPKPLVSLRPVVGQPVRQAGSQDECPSASGVKPEVWRKAAVTAEAARVAEARRRAASEGRQGAKTCPSASGVKPEVWRKAAVTAEAARVAEARRRAASEAGREPRPSARQLPAAVTAEAARVAEARRRAASEGRQGAKTECPSASGVKPEVWRKAAVTAEAARVAEARRRAASEGRQGAKTECPSASGVKPEAAVTAEAARVAEARRRAASEGRQGAKTECPSASGVKPEVWRKAAVTAEAARVAEARRRAASEGRQGAKTECPSASGVKPEDPKFLLVLPSRLAESIRGPSQMALLLQLAEDAPVSGHAADGADPLLFPGRLAESVICIEGRRRWRCCYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P449</accession>
    <name>A0A3R7P449_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxisomal 3,2-trans-enoyl-CoA isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006558</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001832">
        <property type="protein sequence ID" value="ROT74925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P449"/>
    <dbReference type="STRING" id="6689.A0A3R7P449"/>
    <dbReference type="OrthoDB" id="409763at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00435">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000084">
        <property type="entry name" value="Enoyl-CoA delta isomerase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022408">
        <property type="entry name" value="Acyl-CoA-binding_prot_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00880">
        <property type="entry name" value="ACB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="46"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT74925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="370" mass="40007" checksum="92BADEB84848CBBD" modified="2019-04-10" version="1">MASLRCATRLASVYKRGIGAGFGVASHQLAPAWGAAATQVRLMSALSPEFESAKARLGTLSEDPGNEAKLKIYALFKQATVGAVNTKRPGMMDFVGRAKWDAWNSLGNMSQEEAQKNYINFVNSLAGAEEEQAKAQAESGQKYKNLLVTCENGLRTITLNRPAKMNAITVEMYEEWIAALKEAAEDPATVITVTTGAGNYYCSGNDLSNFANISPENMHEHSKNAGVLLNRFVSAFIDFPKPLIAVINGHAIGVSVTVLGLYDAVYATDKATFNTPFSNLGQSPEGCSSYTFPKIMGPGKANELLLFNKKNTSRTVIPLRYWSGLKFTFFSISLNPFVCPPKMAPRSASGAWVNGDSRLSCHSDIGDIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAQ0</accession>
    <name>A0A3R7PAQ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_000957</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001132">
        <property type="protein sequence ID" value="ROT80309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAQ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02394">
        <property type="entry name" value="KH-I_Vigilin_rpt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="507"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="575"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="147"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="713" mass="76160" checksum="54E9B8079EA7FC81" modified="2019-04-10" version="1">MNREGESEADISPHKATTCEVKIRSRVAEIRDLSGRNPRLILAAGPSIECPLREKQPWPTPRLVDLRRQGECNAEALQNLRALAESIKEQKTPMALTPVVAVAASFIVAVIVVLGIRRRASATASPASQPAIEGSFDLPSSLSQPVIEGSFDLPSSPSQAAIEGSFDPAIEGSFDPPSFPSQPAIEGSFDPPSSPSQPAIERSFDPPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDPPSPSQPAIARNRFDLPSSLSQPAIEGSFDPPSSPSQPAIGGSFDPPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSPSFFPITASNRRAGKAAENFGVKLVRPHAGNLVAPFLVKGKQEAAQAFIQHMEDCISGNRPLRMPLQILVDLQLLLKTKQAPGIWLKMPLREDDPSESWALIAKEKDRALMLKKLVDIEGQVRSSERASSDIAPAHYGKVIGKGGARISYIKEKYGVWVNVPKDRESPIVISGLSTNVRRAIKELEELVQQDVLQQRVVLPVEILPEDIGIAIGKGGCHACKVQEEFGVKLRTHSREHPEWPLVVEGPLGAAEKAVASIQLQRHGVTIQLPERNKPGAQILVTGLKENARAAVAELIANLKFRPKHVLVPVHIRREEHILVLGPEGSSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAZ3</accession>
    <name>A0A3R7PAZ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="11">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_016427</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 11">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Phospholipid metabolism; alpha-glycerophosphate cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01003067">
        <property type="protein sequence ID" value="ROT65597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAZ3"/>
    <dbReference type="STRING" id="6689.A0A3R7PAZ3"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="UniPathway" id="UPA00086"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017751">
        <property type="entry name" value="G3P_DH_NAD-dep_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03376">
        <property type="entry name" value="glycerol3P_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="12">
        <location>
            <begin position="18"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="13">
        <location>
            <begin position="137"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="212"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT65597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="307" mass="33638" checksum="A899C6F30AAA80F4" modified="2019-04-10" version="1">MLYSTSNSFSLHFRSKIAVPDVLEAAKDADVLVFVIPHQFIKNICKPLVGQLKPTAVGISLIKGFDIAEGGGIALISKIICDFVHVPMSVLMGANLAGEVADEKFCETTIGCRDPAVGRMYRDLIQTDYFRVVVVDDVEAVEVCGALKNIVATGAGFIDGLGFGDNTKAAVIRLGLMEMIKFCEVFYPGSKLGTFFESCGVADLITTCYGGRNRRVAEAFVKTGKTIEELEKEMLNGQKLQGPQTAEEVNYMLKNKGMEDRFPLFSSIHRICKGEIPPADMVNCIRNHPEHMCTFDKEHTTVTGNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PB16</accession>
    <name>A0A3R7PB16_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative integrin alpha-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_000684</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the integrin alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001107">
        <property type="protein sequence ID" value="ROT80576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PB16"/>
    <dbReference type="STRING" id="6689.A0A3R7PB16"/>
    <dbReference type="OrthoDB" id="5317514at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.930">
        <property type="entry name" value="Bicelle-embedded integrin alpha(iib) transmembrane segment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013519">
        <property type="entry name" value="Int_alpha_beta-p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000413">
        <property type="entry name" value="Integrin_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018184">
        <property type="entry name" value="Integrin_alpha_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220">
        <property type="entry name" value="INTEGRIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220:SF133">
        <property type="entry name" value="INTEGRIN ALPHA-PS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01185">
        <property type="entry name" value="INTEGRINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00191">
        <property type="entry name" value="Int_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51470">
        <property type="entry name" value="FG_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00242">
        <property type="entry name" value="INTEGRIN_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0401">Integrin</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="658"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="repeat" description="FG-GAP" evidence="4">
        <location>
            <begin position="81"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="689"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="689"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT80576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="712" mass="77328" checksum="4C42B9D950615C68" modified="2019-04-10" version="1">MRVAQEHSHKTQTRTHPPPAQQTTQNAERDALRSTKQNEKPQRAKPANPRQTTITKDHRPAPHPHKQSQTTQTINIDDTQGYNVTLHGHSAFGRFGSSVVCLGDVNNDSFSDLAVGASEHPGGGAVFVFLGSSEGLVPTPSQILLAPPNVTGFGFSLAGGRDIDGKRVSGRGGRSAVSDSAVTFRAAPVPKLASRPSASTRPPSTSARRTCDLLGGRLNCFRLLLEVRDEGGHHRESPLKLRVKVNLDSGRRRKRIHFYDNTSSVDMSLDISGNLSKVFDVYAEDLANETDAIPGPIATVNVSLEPHRSVSKEGLLPVIGKPIINTTSLILQCGNDTNNCVAVTDMAFFAEEREINFTVGERYASVEFNVTVTGGNAYDPYISVMDTVGLTAQMGRSSNSPISLDCFRRRRCKFTTMKIRPGTEMIMMLRFEQDVKALLDFMNQTSVVPPSINLDMAGMCVNDKNASNDFLTFKMFPKLRPVLSLVGENEDESISITFADGKGAARVEKNDISFDDENFTVTHNYTLRNVGLFPIQKIAVTCSGKITGIENETLTEYLLSFDPPPEESGTCEAPCISEVYNLAAEKMVKIVLIFANKELNQQHLGQHSINLTSTCRAKVISPSGATVVSEVSDVDQTVTLTTYVIFIVSEGKAGPDSWVIALAMLGGCFLLALLVLALYKLGFFKRKLPPAPPQGSPGPPTPATESEVEEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHY8</accession>
    <name>A0A3R7PHY8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">XK-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009107</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the XK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002141">
        <property type="protein sequence ID" value="ROT72519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6356248at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018629">
        <property type="entry name" value="XK-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050895">
        <property type="entry name" value="XK-related_scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16024">
        <property type="entry name" value="XK-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16024:SF28">
        <property type="entry name" value="XK-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09815">
        <property type="entry name" value="XK-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="585"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="875"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="916"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1024"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1074"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1223"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="611"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="630"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="887"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="916"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1024"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1040"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1239"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU910716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1343" mass="148521" checksum="E7A508A8366644C1" modified="2019-04-10" version="1">MAGSSDEGDTRGDYFRPLPRTDGRTVTPKMPTFTYFDAGFLLVSMATFAVDVGTDLNLVIRYFLEGSVIWAGLTLALVLVPAVVVMIMSMKWHYVEAEAEAEYAANEAEQTSDSEKKPVKTPSVSKLCWLAHICLWGILHRYILLFKSGIRAQRTKDTEDFRDMYRQQSDVCMLRLFESFLESAPQLVLQLYIMMSHHDYSAWTAITALSSMASLGWGIAAYTKAMRNTLPAKHKMTVSGLVLQTFWRMGMIAARVAALALVATVLNEWLLVIMGAHLLVMFIWVVKQKAEYGVSTLEKMIFNFIMAVICCFCFFNLKDGRSRWRMLAFYTVTVAENTAFTLYYFFMSDHQQVLRLAALGLVFGGMALGLLCLVIYYRFFHPIGPIRMFIKDEPGELEKGGKEADNSHTLDSNANSTFRESTRRNIKYMYATATQKTVKCILSAPGVSLESSPASSASQSSASPPLVSHMQRPVEMMCSVQDLLANVSCTSEMQVAEVVEEGTSQSQSEVPEEKKNSEESPVVVEASPSSLERTVTRELEYRLSQSDFRSLCSAGEQSPGTTETSLPQESNQLCIKSVNSGAAIGESVHSSPNSVGIPQKSKTTSQTSVRSGLLSGSQHSGSSILRTSVRKRDATNSETDVRLTSLPHITTSTINLTSKSQEMELDHSEAQLSKAPVPNVELAVIDRMHIIEMESSGTSSENQSDYENIYEGQDARRNLPPKPANLVIAQNLNETQSTQASVPHDYENICAVNINRAMWGLRHWKTYSDIEDRIHDDNEAKDDSRLMAVLNQLRANKAMNKSSSVDNIPNYETIWVGDVAKPDTSNTSSQMSSLTSKSSLVVTIGDVRAKESLCNLYYSTMSDLSFRYYSERMRKNSSSGSLASKRSTRDTSREMMRAISVPDNKTLLEVSQLIEEQKKREEEEAKQTSNQGGATAATPCTPRPLKFGPGATPVRSDPSNNRPRRKFSMLRERFENPNWTPLRSPMKRGPSTQRRNSFQDRTAKALQAGMKVFRRPRVHVITPKKGEDKMDTPRLKSPFKSRNVTPSNTLGLKTGPEPLSTETALKTRLLESEGATAIHKTPHIKTPADNRLTKRTPKTSTPENKQPLVKKTPVPIKGAKKLTEGPKTSTPEGNKQLPQISILSAVSSVVPSPESVLKFNLSDHQQRIPLSENVHQIRTSSKSLAMPAIKEAEYIPSVLLPKPFYGSLQSGVAHGSQGLALKPTRIITSDENSQDIRSRPSSSGLASSQSVLSLKAKQASPLADGGSRLNQNQAMFSGILGLPPYQQEPCRPAIISVTESTENPSGQQNISISRIVLSSPQSPNFNMQKSTLSPTSKIFSRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIZ6</accession>
    <name>A0A3R7PIZ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013827</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002723">
        <property type="protein sequence ID" value="ROT68048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIZ6"/>
    <dbReference type="STRING" id="6689.A0A3R7PIZ6"/>
    <dbReference type="OrthoDB" id="6365500at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097527">
        <property type="term" value="P:necroptotic signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT68048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="26863" checksum="EA3C831A769662BC" modified="2019-04-10" version="1">MLLESEITRLVSEGGVLLGEGVFGWAFRVRYQGRDAVVKMAKDRQHAQLFREEVQTLVQLDGLGGAPRVATICEDYPGFIMDYCGGGTLQSMLKDGPPVGAVLRAVHDLALRLEEIHRAGYAHNDLKVDNVMVETGADGRVRARLIDLGLCGRLGESPGLEGDPKVHRHVAPELLRRGVSSVESETYSLGYVLRDVLRAYAGSLPRESELRCLARAMTCPDPLRRPAYQLCLAGLADSLEAPRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNC2</accession>
    <name>A0A3R7PNC2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_009631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT72011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNC2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="46606" checksum="A4447C2C1555F75B" modified="2019-04-10" version="1">MPSSNILPFARISFPFARISSLLLEYPPYPPFCSNILPFARNILLLLEILLCSNILPFARISSSFCSNPPFCSNILPFARISSLLLEYPSFCSNILPFARISSLLLEYPPFCSNILPFARISSLLLEYPPFALFARISSFCSNILSFARISSFCSNILPFARISSFFRISLFARISSLLLEYPSFCSISSLLLEYPPFCSNILPFAYPPFCSNILLLLEYPPFARIFLLLEYPPFLEYPPFCSNLLEYPSFCSNILPFARISFLLLEYPSFCSNILPFARISFLLLEYPSFCPNIESSLCSNIFLLLEYPPFARISPFANILFARISSLLLEYPPFCSNILPFARISFLLLARISFLLLEYPPFCSNILPFARISFLLLEYPPFARISFLLDILPARISSFCSNNILLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRB2</accession>
    <name>A0A3R7PRB2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RUN and FYVE domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001145">
        <property type="protein sequence ID" value="ROT80185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRB2"/>
    <dbReference type="STRING" id="6689.A0A3R7PRB2"/>
    <dbReference type="OrthoDB" id="9044749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17682">
        <property type="entry name" value="RUN_RUFY4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46753">
        <property type="entry name" value="FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46753:SF3">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="1">
        <location>
            <begin position="28"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="337" mass="37623" checksum="AC6B527564DBD57E" modified="2019-04-10" version="1">MSISDPLIKELKGHVLEATKASSNGAILDIHPFLLPLCQVLESIFRKGLNNIVHSAFGITRRDYWAWIDKTAQTSAGLQGNFKRIVEEVSSNPSINTPQGRGRLFIRHALKSKCLHVPVETIVRMKCNEGIYEEDSIIGDEILGEIFLSLLYQCSHLHFDLKLENASFLDETWQLPQYQEYELVPCMDLGVYLGHVSGRAVVVKVEDGSVAAEDNKIEVGDVIDEAFGICINGWRRGRVTALLRQKRGLPVTLKVIKGHYPNGSVFPGVIPLLRRLHLDVDSLQERFREAALSESQETSLTGSHIGYVLPSPYAMDFLLSRTIMSSRSPLAMSLPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRR2</accession>
    <name>A0A3R7PRR2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Centromere protein L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-L/IML3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRR2"/>
    <dbReference type="STRING" id="6689.A0A3R7PRR2"/>
    <dbReference type="OrthoDB" id="8864979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025204">
        <property type="entry name" value="CENP-L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31740">
        <property type="entry name" value="CENTROMERE PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31740:SF2">
        <property type="entry name" value="CENTROMERE PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13092">
        <property type="entry name" value="CENP-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT80514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="46257" checksum="B4112DEA68ACB8C8" modified="2019-04-10" version="1">MAPKKKPVPQSSKKKSPSKKPAVGVISPRRSPRSPQIRRKLPKRTHPYPSPKPTVPAKKKSLDVEKTPTTNVQRQSSVGSRQDSSSTPTTPRQLNICNLSSVHNFRYNFKNLRKQYEGTLKRMIEDVFASSMLTVNFSTTSFFSLVPNVVDAIYIQVNSLVPGNTVEEDKMMIVYSCWLFKTSHTQSKNIPGVEWFPVMLYTGRNVIHNVVVDWLQGSFDCYVTRRQLRQTDMMWIAGVWSGRKCFTSAHQRGEGSSIDFTYHVRHPDGTSNYPVPNTRSKLKLVMKLNMEDVHHIWDTIVDSSRGEMSVEELQLFFNTIGDCAQQLTFLPAELLQLQQLSTPCLSITSAGKVKLTCVRSASIVVNHLIDIFIQAMNCSALEDHLLKADEVAESETSVFLTDDEDKEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTE4</accession>
    <name>A0A3R7PTE4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_024735</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000883">
        <property type="protein sequence ID" value="ROT82113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTE4"/>
    <dbReference type="OrthoDB" id="6375714at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018706298" evidence="14">
        <location>
            <begin position="21"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="343"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="563"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="15">
        <location>
            <begin position="239"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT82113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="601" mass="66932" checksum="7C8F1C453B0FE65E" modified="2019-04-10" version="1">MKPLLASLLLGLCLEPPASARWSAGGPPEPLEATAKRAMRELSQGPLQGRRLSVLVDVEAEKSVDVGELLSSMGAEAYLTRTGGEGDPGPEAFEGELEDNLVEGEFAHENASREMVVGDVLVALVGDKVPWPLTSPPPWWGPSAVLIIGLSLQCQAARVFQMALVERTTWVSYLCPIRTQGQARFTVLSWLPFDPDQRLVSLGIWEPESFSTFSQLFIDRFKSMGGHTLNVASDDDDAPLLFLDENDEFEGTCKRILDSLADAFNFTFTLTHGAPDLKWGEIENGTWVGLLGEVYRGRKDLAINYFTITYERAQYFDYSISYHTEGFGFALPRPPPLPQWRSLVYPFTWVVWVGVSVVLVFTGMAFFFLTYTQPVAPDVSLPGAFGIIMMGLVNQAPTKIPASWSLRVFLAGWWITAYIIVISYNCNLIAVLTVPVYPKRIQTLEQLADSHYRLCMLDYGEFVPDALLQSAEPVMSSLGRKMDLVAVTEEGFYGQEDCAAHVLADSNAHIETYAYLQLTYADMELLDNVYFMKSQIYEGNLAFFYRKHTPWRRVARGSIPQPLALGHLQGVFFVYGLGLATALLVFLVEARLTARKDHKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVE5</accession>
    <name>A0A3R7PVE5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative TRIO and F-actin-binding protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000634">
        <property type="protein sequence ID" value="ROT83763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVE5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="643"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="765"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="792"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="846" mass="92355" checksum="9129A84C979688E6" modified="2019-04-10" version="1">MSLTLPPAFLNPESLGLRNPYRRESGSHRGSRQEEPELEAATEVAQEEPELEAATEVAQEEESELEGATEVAQEEEPELEGATEVARRRRTPRRSPRRRSPNWKEPRRSPQERSPNWKEPRRSPRRRSPNWKEPRRSPRRRSPNWKEPRRSPGGGARTHGGRPGGGARTGRSHGGRPGGGARTGRATEVARRRSPNHGGRPGGARTGRATESPGGARMTQLKGSSMTRRSPNWKEPRRSRTPRRFAPRTGRSHGGRPGGGAELEGATEVAQEEEPELEGATEVAQEEEPELEGATEVAQEEPELEGATEVAQEEEPELEEPRRSPRRRSPNWKEPRRSPGGGARTGRATEVAQEEEPELEGATEVAQEEEPELEGATEVAQEEEPELEGATEVAQEEEPELEEPQVAQERSPNWKSHGGRPGGGARTGRSHGGRPGGGARTGRSHGGRPGGGARTGKPRRSATEVGGSPNWKSHGGRPGGGARTGRSHGGRPGGGARTGRATEVAQEEEPNWKSHGGRPGGGARTGRSHGGRQEEEPELEEPRRRRSPNWKEPRSSPRRSPNESPTTQLQRFFNVTYILALPQPPINLETLEQLFYDKMINSQFATHLFELRDFSAWCSTGELTTCNISFIFVITQEVAQEESELEGATEVAQEEPELEGATELAQEEPGKPRRPSFKGSSIDLHLALPQPPINLETLEQLFYDKMINSQFATHLFELRDFSAWCSTGELTTCNISFIFVITQEVAQEESELEATEVELEAATEVAQEEPELEAATELAQERARTGSSHGARPGGARTGSSHGGRPGGGARTGSSHGGRPGGARTGRSHGSWPSVMIRSLLKMPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWH4</accession>
    <name>A0A3R7PWH4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Gamma-aminobutyric acid receptor-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_021897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000474">
        <property type="protein sequence ID" value="ROT84904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWH4"/>
    <dbReference type="STRING" id="6689.A0A3R7PWH4"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="5">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT84904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="16437" checksum="BEE67030254C64AE" modified="2019-04-10" version="1">MKWLYKAERPLAERVAECKRILSKYPDRLPVIVERADKTRFEDLDRKKFLVPKDFTLGQFYYIVRKRVRLEPEDALFLLIGRMIPPASALMGELYETHRDSQDGFLYVAMTDESIYGGEGGGLRAEAAAGWSSSHLAVSSVCFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWM0</accession>
    <name>A0A3R7PWM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001863</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001249">
        <property type="protein sequence ID" value="ROT79415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWM0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="712" mass="75733" checksum="2C4A8DC653EC5CE1" modified="2019-04-10" version="1">MPSRRARSYSSDFLLGSFATSASSWLRLPPRATSASPRALGDFGFLLAFSWLHFGDFGFLLGALRRLRLSSSVLRALRLPPRVLRRLRLPLGSSATSAPLGFSATSASSPSAGLRRLRLPLGLRRLRLPRLRSLRPSLGFLLGSLRRLRFLLGSFALRSSSVFGDFGFLLGPSATSASSSVLRRLRLPPRVLRRLRLPLGLGSFGDFGSSSVLRRLRLPPRSFGDFGFLLGSSATSLPLDFGFAPGPSATSASSRVLRRLRLPPRVLRRLRLPPRVLGDFGFPTSASSPSATSASSSGLRRLRLLLGFLRLRLPLGSFGDFGFLSGPSATRLPPRRLRLPPRVLRRLRLPPRVFGDFGFLLGRLRPSTSASSRLRFLLGSFGDFGFLLGSFGGLRLPLRVLRRLRLPLSGFGDFGFLLGSFGDFGFLLGSFGDFGFLFGSFATRFPPRVLRDFGSSSGPSATSASSSGPSATSAPPRFLSGSLPRVFGFLFGSFGDFGFLSGPSRLRLPPRVSASAPSATSGSFGDFGFLFGSFGDFGFRLPPRVLGDFGFGSFGFLLGLRRLRLPLGSFGDFGFLLGSFATSASFGSSATSASSGPSATSASSFGSAFLLGFGDFGFLLGSFGDFGFLFGSSATSASSSGPSATSATSSGPPATSASSSGRLRLRHFGFGSFDFSAFCKGLKTTVAPPRLKAQLLQLGASSPFRRDLLRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWR0</accession>
    <name>A0A3R7PWR0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003931">
        <property type="protein sequence ID" value="ROT61918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWR0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="40912" checksum="BF578031713EF530" modified="2019-04-10" version="1">MAPSSGSNSVWHLSSGSISMWHRFSSSSGSSSMWHLVLRIQQRVAPRPQDPAACGTVSPRPQDLAACGTVSPRPRDLTACGHLVLGIQQRVARGTSPSIRAPSPQRARTSMPNQSELRRPCERVQEPKSPQDLPSRLHLRLLLPLPRLRTRPSGTRSPPLIPSALLLRRRCVPEAKIGSPRASQASCPPCPDLAARSRTASRLTPSRTSIFHQCLRPGAATTDSESGWTSASFDIRVLVDIRVLVDIRELCRRNSPPDAITLRCGGGLILLFECWSSSEVLLEDLPPRSTSKLLSRSPPPRSSLKVLLKDPPHSSSSKVKGPLKGPPQRSPSKVLLIAPPQRSPSKVPQKLLKVPLKGPPKLLLKVHKAPPQRSTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZH1</accession>
    <name>A0A3R7PZH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000892">
        <property type="protein sequence ID" value="ROT82047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZH1"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT82047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="16911" checksum="EDEDDEB36D0D7902" modified="2019-04-10" version="1">MVESATCCQRCSVSWSVVNHGEVAPGKVYLPSLVLSVCSVKVKVKYKMRPALILALAAILAVSVVDARLNICSSTADCPPRSQCVRKRCSDKCSSMSDCLPGLGCVLGRCMDVCDGACSVSAKCDVILNEPVCSCPEGQEGDPQELCVAPAQKDAAKTPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZS9</accession>
    <name>A0A3R7PZS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative restin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003178">
        <property type="protein sequence ID" value="ROT64830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZS9"/>
    <dbReference type="STRING" id="6689.A0A3R7PZS9"/>
    <dbReference type="OrthoDB" id="5412539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF82">
        <property type="entry name" value="CAP-GLY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="2">
        <location>
            <begin position="63"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="2">
        <location>
            <begin position="183"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="32376" checksum="45E07C22CD3C6686" modified="2019-04-10" version="1">MGSLKRTVGATGRTSSLPAPKVPATKKLATDASVVLTEDTDSFIIGDRVWVGGTKGGHISYIGETQFAPGEWAGVTLDEPIGKNDGSVAGVRYFQCEAKKGVFSRLTRLSRTPLTDQDIEILTSRSSTVGSDSPKTNGTPAASVASGPTSSTTPSVSSDLKVGDRVVINSASGVKHGTLRFIGKADFAEGIWAGVELDEPNGKNDGSVAGKKYFECKNKYGLFAPVARVSKFTGGSGTPRRTSSLSQTPRGSLRRSNSKESIGGSSVASSTTSSIRGTRVRLGVTSLSPGQVPCLPVLLSFVDVVVRGSGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q083</accession>
    <name>A0A3R7Q083_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000797">
        <property type="protein sequence ID" value="ROT82613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q083"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1251" mass="138666" checksum="336920C8AFB9EBB0" modified="2019-04-10" version="1">MENGASIRCGSRREREPYRAKSTQIRFRCSSSGAALVLCVGEERNPKAWGAEDGLCRSPLPDGALSRSHNFWHAFCVGTPINLFSEPVAQERSRPPRPDALRIPPPGRRQVANAKPTATTTAEPTAINNLAQLGGSTCYTCSRPVPPAHDLLQLLKTCSTCSRPVTTAHDLLQLLTTCYNCSRPVTTAHDLLQLLTTCYTCSRPVTPAQDLLNCSRPVPPAQTCSTAHDLFHLLTTCSTCSDLFQLLTTCLFTTWTHDLPPAHDLLQAAQDLFHLLTTCYNCSRPVPPAQDLLQLLTTCSTCSRPVSTCSRPLFHPAHDLLQLLKTCYNCSRPVTTAHDLLQLLKTCSTCSPDLYILLTTCSPAHLLQLLTTCYNCPRLSTCSRPVTTAHDLLQRLLKDCYNCSRPVTTATRLLYNAHDCYNCSRPVTTAQDLLQLLKTCSTAQDLLQLLNLLNLLQLPRPVTAQDLLQTCSDLLQLLTTCYNCSRPFHLAHACLLNDLLNCSQDLLHCSRPVNAATTCLHLLKTCSTCSRPVTTAHDLLQTADLLQLLKTCYNCSRPDTPAHDLLQLLKTCYTCSRPVTTAHDPTWLRPCFHCSRPVTLASRPVQLLTTCSTCSRLFNCSRPVCNCSRPVTTAQTTVHPAPDLFQPAHDLFHLLTTQPVNDCYNCSRPVQLLKTCYNCSRTCSNLLKPVTTAHDLLHSHDLLQLLRPVTCSRLLQTAQDLFPPAHDLLHKTCSTCSRPVTLLKTCTLKTCYTCSRLFQLLKTCYNCSTCHLLRPVTLLFHLLTTCYNCSRPVTTATHCSRHTAQDLLTHNCSDLFTPAHDLLPAHHCSRPVTTAQDEDLLQLARPVTTAQDLLPVFHPAPRPVSQLLQLLTTCYNCSRPVTTAHDLFHLLKTFHLLTTCSAHALLQLLKTCYNCSNVSTAQDLLHCSPVPPCSRPVTTAQDLLQLLKTCYNCSRPLQLSRPVYNCSRPVTNCSRPVTNAYTCFTTCYNCSRPVTPAHDLLHLLTTCYTCSRPVTTAQDLHNCSKTVTQLLVTLLKTCSTCSCPVPPAPCYRLLKMCLQLLKTCYNCSKTCYTAHDLLPTCSRPVTTARSSPTCYTLRPVTTAQDLLTAQTCSMPKTCYNCSRPVKPTTCLHLLNCSRLFNCSRPVTCSRPVTAQDLLQLLTTVTPAHELLQLLTTVSTCSDLLHCSRTCYNAHDLCYTCSNDLLQLSHLLHLLKTCSTAHDLLPCSRLLPAHEPALTPLKTSYTCSRYTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3S2</accession>
    <name>A0A3R7Q3S2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002757">
        <property type="protein sequence ID" value="ROT67795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3S2"/>
    <dbReference type="OrthoDB" id="6355654at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="2">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="41690" checksum="0C135B30C690E80B" modified="2019-04-10" version="1">MKYGIEVSPDETPPKGREEGEMREEVRKNPDGEADPTTMASPVHSRLAGMKLEEAADAVVFSIQFYGKTIGEVGLMDQDLSELDWKKFKSYLFQNLLSINQQDNICVSYSDEEGDKLPIESDEEYREALKVAKKKAEMHDKMVLDITRQGGLPTVLSFVSSGIKKVGSSPPKERGMSFFKASSPPKESGGFMAKDWKPFPPFFMPDKGPIPGHVQGMWGYDCDEALECDKPHHTTTTATTTTTTTTTTAMSAPRTDCKKGPPVRSLRNSPPNLLFKFEAPSPNIKSEPPHSATTSQAVFGAGTGGSAGGGARSKVPQEATQRPEQPPAWFTTYMEKFRKEISEEVSECVMEKVSGMIKEMKFPSTPRKSNIRVSSSSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q7A4</accession>
    <name>A0A3R7Q7A4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase family 3 member B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011378</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002440">
        <property type="protein sequence ID" value="ROT70328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q7A4"/>
    <dbReference type="STRING" id="6689.A0A3R7Q7A4"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT70328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="354" mass="39907" checksum="F6E6D9A24F0DEE46" modified="2019-04-10" version="1" fragment="single">MNRLIQQAREAFHSGRTRDVEFRKKQLKALKRMYEENESVFCAALAKDLHKPKQESVLLELNLLKDDITHILARLDEWAKPEKIAANLVTMFDTPVIYHDPYGVVLIMGAWNYPLQLPLLPLSGAIAAGNCVIVKPSELSPATAQAIAELLPKYLDSDCYHVICGGIPETEELLKQRFDYIFYTGSPHVGKIVRDAANKYLTPTTLELGGKSPVYIDDTVNMDIAVRRILWGKCINLGQTCIAPDYILCSKEVQDKFVSKAKEVLKEWYTENPQKSPDLCRIVTDKHVNRLEEYLKDGTIAVGGEVNKEDKWISPTILVDVNPESKVMTEEIFGPIMPIVNVSSAYEAINFINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGG2</accession>
    <name>A0A3R7QGG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DJ-1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001430">
        <property type="protein sequence ID" value="ROT78112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGG2"/>
    <dbReference type="STRING" id="6689.A0A3R7QGG2"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051896">
        <property type="term" value="P:regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000022">
        <property type="entry name" value="protein deglycase DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="4"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="16491" checksum="31D7441C0B9B6BF0" modified="2019-04-10" version="1">MFSQIEVTVAGLNGAGAVKCSRDVVVVPDAALEDAAGKGPYDAIVLPGGLKGAESFGQSATVKTLLTDQQKAGRVIGAICAAPAVSLPPHGIGEGKKVTCYPALKDRLDAGKYTYQDQKVVEDGELITSQGPGTAFDFGLALVKKLVDSEKSASVAKAMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHS2</accession>
    <name>A0A3R7QHS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ecto-NOX disulfide-thiol exchanger 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002740">
        <property type="protein sequence ID" value="ROT67883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHS2"/>
    <dbReference type="STRING" id="6689.A0A3R7QHS2"/>
    <dbReference type="OrthoDB" id="10039782at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007624">
        <property type="term" value="P:ultradian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038876">
        <property type="entry name" value="ENOX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16001">
        <property type="entry name" value="ECTO-NOX DISULFIDE-THIOL EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16001:SF4">
        <property type="entry name" value="ECTO-NOX DISULFIDE-THIOL EXCHANGER 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="23235" checksum="0354744BDA407972" modified="2019-04-10" version="1">MRINNSTEAANTGRLHVDYAQARDDQYEWECRQRQLQREQRHRERIEAERLRPPSPPPVVHYSDHEATIIAEQLKGDDTFSKAVQIVITWLERGDCSKRNAGTFYSMIQSTNSHVRRLMTEKSQYEEELAKFREQTRARMQGVIMQFGQIERVFMSAGHQKVWDHFTKAQRRNIEMWKKQAEVCHASCTPIHSVCCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKU2</accession>
    <name>A0A3R7QKU2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024791</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C65 family. Otulin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000892">
        <property type="protein sequence ID" value="ROT82050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKU2"/>
    <dbReference type="STRING" id="6689.A0A3R7QKU2"/>
    <dbReference type="OrthoDB" id="10682394at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990108">
        <property type="term" value="P:protein linear deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22790">
        <property type="entry name" value="OTU_OTUL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023235">
        <property type="entry name" value="FAM105"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023236">
        <property type="entry name" value="OTULINL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33662:SF3">
        <property type="entry name" value="FIBROUS SHEATH CABYR-BINDING PROTEIN-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33662">
        <property type="entry name" value="OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16218">
        <property type="entry name" value="Peptidase_C101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02055">
        <property type="entry name" value="PROTEINF105"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02056">
        <property type="entry name" value="PROTEINF105A"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="449"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="614"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1039" mass="113370" checksum="210090F78ECD7E88" modified="2019-04-10" version="1">MRREWCRRADGPARSARGSAGSGRRPRGILASLLEDDLVQDFEDLDDEDPALIHHLIELGREFVVKLLVGKYFGPDSPCGEGPGEDLSLVSSEVSEVSEVFAHHYLADASASISAGDVGSSSGENSLPTDEDSDVELFGGHKRVVRRKHRSSELHRNQLTPSHGRAPGGGGGGRGSTAAPNASVVAKKHKTESKHAAKRQGTGQHPLQDDWCSSESSPAHGAPTSAHLPQVKELTRHLGDGSRRRPERGSCSSPKVGKRRHQCGSALRSSQTRDQEDWLVDSRLQPEGEEESHLSTNISSASLSDLMEKMRHRGCHGSISRDNSIASNMSDFVTSPQGSKRFTFKREDSVCSNLSDFAPSECSEMSLDVSVRDDLACKTFTYLDDIEHELDDLKSSMLEMDEEVTKFASKPNPYTFKTTYSDYSITSGDSRPNSALDLVNAHRSRASFRGVFGQKGTGSSDSEALEGGPADSTHTQGHVVSGSEAEGSFEWDSPQHGWTSARGPPLSRLPELPSEDAESSRASTQEDMMPSLEWDNDCLQQYDEEQMQDSHNSQLDEVFHRNNCERHQLLPDHSSLELDLEEELQAATNPLTEAADLRSAPMTISVDSAIHSATGSRSASSSPLPTGLGQSLLSSSGLASSSEISPATPDSESAGWGSWERRLGPGEFGSKARRYWSSEESGYMEGPDTPLDTAIHAHLSPVHEIKEKEYSESSGSSPTHHTDPKEVTSEGGNLNETALESNLNGNLIMGSTASTANDNEHILGTTTAAFGNQPTVAVGQRIEVARYASQEWRGNTAKAHTIKQGYSAIPVELNYHYLRRVRGDNYCGVRAALYQILSQGLPVPSGHATHTRLAAELNQGSTWLRDWSFGHRLSFSKEQVLNGFWECLDALDSMVLSLKGCENRECVVLSRLNSDPLLDVKLCEAVKLHMLATALDLHIGNNNGDNVPLFSMIMFARHTSLTPRDFVKNHLNLVGDTAGLEQIEMFLMGHTLGVTLQVVRPACYGKDDFICYYPDANIGVWPEVTLVAEDDRHYNVLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYI8</accession>
    <name>A0A3R7QYI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000685">
        <property type="protein sequence ID" value="ROT83447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYI8"/>
    <dbReference type="OrthoDB" id="6630425at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF79">
        <property type="entry name" value="CUTICULAR PROTEIN 50CB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018626447" evidence="3">
        <location>
            <begin position="26"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="123" mass="12989" checksum="716FAA9303379D89" modified="2019-04-10" version="1">MLLVLHHTFLKQVAVVLVVLATAQAHPGNQGPAYASGPIPYGFNYAVNDAYKGTNFGQSEKSDGNSVWGSYTVALPDGRKQTVDYTADHGRGFVAKVSFSGKAQHPKVSGPAVVFPQNGGGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7R070</accession>
    <name>A0A3R7R070_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000227">
        <property type="protein sequence ID" value="ROT85624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7R070"/>
    <dbReference type="OrthoDB" id="6356350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="615"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="672"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="806"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="839"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="881"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="915"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="949" mass="105653" checksum="11D98D200CCEF6D4" modified="2019-04-10" version="1">MPGKPERVTRSKHAGTLSQPSSRAPTCASTSVEQMPVIVPCSNPEVRQAVRAMEGEMTLFSEILDKIGALSADIQEIKSQTQDFGERLARQEEATHQQGVETASTTHSSPQRALPTPTPEQAQDSSRDEQIATLRRLLKEKERELEEEKRKSRPRDAVQMYGRNDATCDLPRPLPRGHFSFTALKRNQEIEGWIRSIENLVKPPTSESFIQAARASCRGPADLIINSPLFDFIRDWDTFKAALRSKFRGTYTAADFYKVLYENRMAAGQAPFDFYQQLEGSVYQGYRDHKEAIGDPSELIRRVFLTGIPPWLRDFLALKEDCPTSQLAETAQRIWNSRNGIRHRESTSRHQSPNDFPGDDSVGRHNYPPRPPRTRDAYAYAVAAEQDEVASPYPAPSRWCEYHRSSGPAILPGSVPFRPARMAELQAPLAVSQQGAVTTTSTQTELHEPVISVVNAAGPTGRPLVGLNVNGRTTICFIDTGSEATLIKSSAAILTDACRKLRSRSSSKILRGVTGQPLHVTSEWTLAFNLDDNLTVPHQAAEVDTTFPGDILVGMDLLRRLNFTLSHSTITNNAVLTLEGREFSVVYTDHKTLGICPVTRNKTLPTTRKVARTRFYFFYPTFNQLLLILLYSYPDSFSSRLHLFSHSFSPHPLLVLSLVLTRSPRSHSFSSFSSFSLVLLLVLVLLLVLLVLLVLLLVLSVLSFSPRSLISHSLLVLSLILSFSRSFSPHSLVLSFSPRSLAHSLVLSLILSFSRSFSPRSLVHSLLVLSFILSLFSRSFSPLSFIHSSFSLVLSFISHRSFSPRLSFVLILSLLSLILSSFSRSFSPRSHSPRSHCSSLSFSILSSFLSLISLVLILSSFSRSFSPHSLILSNLSSFSFSHSLLVLSLILSSFSSFILSSFSRSFSPRSLAHSLLVLSLILSHSLLVLSLILSFYCGRTLEKEQQHPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STN7</accession>
    <name>A0A3R7STN7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calponin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001877">
        <property type="protein sequence ID" value="ROT74556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STN7"/>
    <dbReference type="STRING" id="6689.A0A3R7STN7"/>
    <dbReference type="OrthoDB" id="21595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000557">
        <property type="entry name" value="Calponin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00402">
        <property type="entry name" value="Calponin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01052">
        <property type="entry name" value="CALPONIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51122">
        <property type="entry name" value="CALPONIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="19822" checksum="40E46BFD5BBA30AE" modified="2019-04-10" version="1">MPRSFQSSTRARILGSHRLSNNNSLPPSISPYFNFPLFSVNTVHSNLIPLPSNHCFPSTAMRFLNPHSTLPSFRLRPLSMLRTPTTTSQSFDRLLLHLFSTILHSNLLPPPTTPACQTYQHPEWPGPWLGPRPAEEHHPEFNEEAIIAGKATIGLQAGSNKGATQAGDNTGAARRVILGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZL8</accession>
    <name>A0A3R7SZL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Caspase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_023638</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000722">
        <property type="protein sequence ID" value="ROT83178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZL8"/>
    <dbReference type="STRING" id="6689.A0A3R7SZL8"/>
    <dbReference type="OrthoDB" id="6097640at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002138">
        <property type="entry name" value="Pept_C14_p10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF8">
        <property type="entry name" value="CASPASE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00376">
        <property type="entry name" value="IL1BCENZYME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50207">
        <property type="entry name" value="CASPASE_P10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Caspase family p20" evidence="7">
        <location>
            <begin position="544"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p10" evidence="6">
        <location>
            <begin position="687"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT83178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="771" mass="85090" checksum="A0FEB48F8D00AB2C" modified="2019-04-10" version="1">MPARPCRCPVPVNGSLPASVLSGNLPFLLISPFRISFPLLPCLPFFPFSLPFLPPPEDAPSVLSGNLPFLLISPFLISSSSLFSLSHFPPSPPCLLSSLFSPSHFPPPEDAAVPQPALFFLSLPFAFPSSSLFSLFSFPPSPLVSLSSLFSLSHFPPSLPPPEGRGQSVLSGNLAEVRAWLAEEGSDVNAADQLGFPLLYTACATGHREIVRELLRHHDLHLNARHSGSEKYVVGRDCRDLTPLCVAAFNGHEDCVELLLKASLPCQIDTSAWPRHSGTAIMSASDNNHWNIVSLIFHHQRRLSLKELDHILARARANNRLPLVLSIVYELFSRSVGRREWSQASSLLKRLREDAGLCVPLAEAVIGRNAGEVRGILREESQQSVDGVLLAAAVEGSSEDVVEVLLKHVSYAEDTLRHALLLTSLNNNLEILPALLRQFLGSYKYATLSQARRIAEEAGYRDAERLLASALEAAARACVVSTWRFSWTFLDCHSINETADLVAPPLAPHLRSSSQLCLEPLVVASAAGPLVSADASCYRTDTSPRGLVLILNYKEFKGKPELLREGSELDVSNLQSTFGQMGYATQVHMNLTEDQTMLNVIRFREQDGLRSCGSVVVVVMSHGVARQTFHTSDMQVFTVDKLLSLFSDRECPRLKGKAKVFLFNFCRGLDVSRMAYQTDAVRTAHNDMLCVYSAQEGFVSLRHPVLGTPFIRTWCQVLANNASNTNLERLLQKFMKQYSETAEGVSVEVQNLNFNKEFWFMPQQKQTPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZV3</accession>
    <name>A0A3R7SZV3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dixin-like isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000687">
        <property type="protein sequence ID" value="ROT83425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZV3"/>
    <dbReference type="STRING" id="6689.A0A3R7SZV3"/>
    <dbReference type="OrthoDB" id="10007451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd21213">
        <property type="entry name" value="CH_DIXDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="557"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="807"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="902"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="670"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="834"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="933"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1057" mass="115367" checksum="AC16B74745B160B0" modified="2019-04-10" version="1">MFLLSGGVDSDSPPPLPSSRPPPPPSHPPPPVPPHGPALQSMSQHPQPPLPPVPRPGGATPPAGAGHVHASPRGFAREEPGARFRSPSNPPRLQAALPAPRPAPAPALRPPPAPDPASSRRASRGPYQPPPPPKMDAREPREGRERELRDPRDPRDARDPRDAGDLQWDARDFRGQQDARDHAQDGRNFRDIRESWERRNATDFPPRREGGRGRQDRVPPAGVLRGMALALQGARLGLRLAHAPRRRRRRGAALPGLPRVSRRPRGVPSPRRRGHVLPVHRGPAQRLTDVAVPDHPAGEAALRRRPPARPRLAARLPRGGLAAQPRGAAAPLHAPRTPRAASPEEALLSDSVYPDAQPRYAEIPDARAKDDRGGNRLSRDLRELREPRDARESRKDLRESQEARTSRDNVRLRGFRETSLPRDFRDSRDPRGSYLEVRDDRGFRELSVDDTDDLEDDLDPRLQERLRGRRDSRQYASERGVDPAKEARLSRGDALRVRDTPAASAYERRDRNADGADGLQVADEHRGQRPPSARAQPERRGDGCPSTSSSVSWMEWTQQLQAYVAWVNSQLRKRGRPLISDLRRDLQSGVVFADLIEIISGEHVAGVTRAVDSPQVMRENLDRVLQFMAAKRIRMTHITSKEVVEGNLKSVMRIILALAAHYKPQSVKGNNNNSNNSSSTSPQHQHESSPLSSSSAVVAGQATTSSGPSGRSSGGAPPPTTHDVGVGPDAPPSSTAPEKTPNLSANRRMMAAGASAEDAGGVVGLRRHPSMTGTPAAARDSSPVYENLPRRVASNRWAYDSLRASHKFQWGGGSSSHARRGPGGAPVVPPKPSPSLDESSDDPLNSSFNASLNTSLNTSMEGDAEASSPRRDSSGSRGGGGGGGTRPAALNFWQDLTRKDASFQPPQEPLTAPVAPQKQAPATDDSDNPFRYHTIHRMSGRRKLPQIPGAAAGRSQNSSPATSLVREATLDQWPREKGSLDPWEQEDLKGVLRDLNTTRDQLLALQNLVSSVLRSCAFSSFLFLAYYEPKKNPRRKPQTPNPKPTSVSDYPRDFPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T161</accession>
    <name>A0A3R7T161_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000453">
        <property type="protein sequence ID" value="ROT85037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T161"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="672" mass="72989" checksum="C64DF3C47B11DB04" modified="2019-04-10" version="1">MAPFGAFFPTVEKFPTSPPTPKNSLLLTHTQNSYLPHPPKKFLSPTHPQIFPTSPTPKIPYLPTHPKNPYLLHPSQKIPYTTPKNSLPPHPQNSLLPTTPNLPYSPPTPKIPYLPHSTPKFPTSPPTQKIPTPTTPILPPLFPLPKSSYPPPPQKFLPPPPTPKIPTSSPTPQIFPYLTHPKKSPTSPPTLQIFPTSPTSPQIFPTSPTHPKSSLLPPPTPPPPTHQSSLPPPPTPNLPYLPHPPPNLPYLPPPPNLPYPTYLPTSPPPPNLPLPPPNPNLPYLPPTPQIFPTPQPTPQIFLPPPTSKSFLPPPPPQISLPPPPPPNLPYLPPTHPKSFLPLPPTPKSSLTPHPPQIFPNSPTIPKSTSPPTPNLPYPHHPKSSYPPTPKLPYLPHPPPNLSHSSHPPPNLPTSPTPQIFLPSPTTQSSLTSPTPPKSSLPPPPTPNLPYLPTHPKSSYLSPPPPNLPYLPPTPKSSLPPHHPQISLPPHPPPNLPYLSPTHPQIFPTSPPTQIFPTSPTHPQNSLSHHPKSSLLPPPTPQSSLPPHPPPNLSTSPTTPKIPYSPTHPQIFPTSPTHPQIFPTSPTPPLSPHPPQKFPLPHHPQIFLPPHPPPQIPYLPTHPNLPTSPTTPNLLLSPSTPTNSPPPLPPHKFPTSPTHPQIPPPTTHPVYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9S0</accession>
    <name>A0A423S9S0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004451">
        <property type="protein sequence ID" value="ROT60973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9S0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="40086" checksum="4DA102B2335D8344" modified="2019-05-08" version="1">MSQETATGALRRPPAAPELQHDTSRHASRALDDSSCQLSLSTPPAPPGPSPTTSSCLTGLRDLQLPPGPSRLLLTRGTQTELQAEGLRRPLQLATAAQTTSDGTPDCHPGPQTDTAPSDTFPAAPGPQTTSSCHRGEDDLQLPTGPSDTSSLPPGTPPQTTSSCHRGLGQTTFSCHRASDDLFQLAPGPQNRPPDDPPSMHRGPQTRQLPPLWLRRLSWHRGPQHTYQLPPPRCPGPQNDLTSHATGPQTTSSCTGPSDDLQLPPGPQSHVRLRALMPPGPQTTSSCHRALRRPPAATGPSATYLQLPPERTQDETTPAATPSRRPPAASGPFRRPPAAHGPSDDLQLPPGLRRPPSCHERPPAARRPSRRTSMAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAE7</accession>
    <name>A0A423SAE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004300">
        <property type="protein sequence ID" value="ROT61180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="490" mass="54513" checksum="3652654358A5E7B2" modified="2019-05-08" version="1">MSPSHFPIPPPSPLTQPPISPSQHTPNSTNPNPPPPRFLLPSSSTFPIPARGDFPFPPPHPTLPILLASCYLRPQLPHPPREETPIPPTPHSTNLPSSSLLVTFVLNFPHPPREETSHSPHPTPTLHKPPILLASCYLRPQLSPSPREETSHSPPPHPHTPQTSHPPRFLLPSSSTFPHPRERRLPIPPPPPPHSTNLILLASCYLRLNFPHPRRGDFPFPPPHSTNLHPPRSCYLRPHFPHPPREETSIPPTPPPHSTNLPSSSLLCYLRPQLSPSPARGDFPFPTPPPHSTNLPSSSLLVTFVLTFPIPRERRLPIPPTPPHTPQTSILLASCYLRPQLSPSPARGDFPFPPPHPHTPQTPILLASCTFVLNFPIPRERRLPIPPPTPTLHKPPNPPRFLLPSSSTFPIPRERRLPIPPPHPTLHKPPILLVLVTFVLNFPHPRERRLPIPPPHPHSTNLPSSSLLVTFVLNFPHPPREQTSHYAAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFA6</accession>
    <name>A0A423SFA6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003533">
        <property type="protein sequence ID" value="ROT62861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SFA6"/>
    <dbReference type="OrthoDB" id="5406014at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1415"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1498"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="769"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="829"/>
            <end position="845"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="861"/>
            <end position="877"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="931"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="972"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1154"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1356"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1504"/>
            <end position="1513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1561" mass="164234" checksum="D997B2ACCD028FF4" modified="2019-05-08" version="1">MLRSASHSPPPRSAPQSPTLRSAPLSPTLRSPPQSPPPRSASHSPPPRSASHSPPPRSPPQSPPLRSASHSPPPRSAPLSPTLRSPRSASHSPPPRSASHSPPQGPSHSPPRSAPQSPTLRSASHSPPPRSASHSPPPRSASHSPPPRSAPQSPTLRSASHSPQGRLPIVHPKSTQGRLPIVTQGRLPIVHPKSTPRSLPISPPKVGPIGRAQNPPLRSASHSPPQGRLSHSPPQPPRSAPKSTPKSTPRSAPQVHPKVAPKSPPRSASHSPPPRSLPIVQSLPHPRSASHSPPKSASQSTPGRLPIVHPQGRLPIVHPKVRLPPPPRSASHSPPQGRLPKVPLRSASLPRSAPPQGRPIVHPKSPPTSAPKVQPKVSDPKSNPIASTKSTPKVGFPIVHPKSTPRSASHSPPHPHSSPPPRSASHSPPPRSASHSPPPRSAPQSPPLRSASHPPPSFPTPKSTPKVGFPSPPKGRLPIVHPQVASHSPPPRSAPQSPTLRSASHSPPPRSASIVHPRSAPQNPPQGRPSPPQGRLPIVHPQGPPKVAPQSPTLRSASHSPPPRSASIVHPKVASQSPPKVGLPIVHPKVGSPPPSRPSPKSNPKSTQGQRPKIHPKVGFHSHPQGRLPIVHPQVHPQGRLPIVHPQGRAPQSPPRSRPKSNPKVASKVHPQGRLPHSHPQGRASHSPPKVSAPSPPLGRLPIVHPKSTPRSASHSPPPRSGPNHPKVGFHSPPQGQVHPKSVPIVHPQASASHSPPPRSASHSHPHPPPKVGFPSPPPRSASHSPPQVGFPLSHPQGRLPIVHPQGRLPKSNPKVGPSQGRLSHPIVHPQPPKHPQGSHSPPPRSASIVHPQVGFHPKSTPRSASHSPPPRSASKSTPRSASHSHPQGRLPIVHPQGRLPIVHPKVGPSPPPRSGPKSPKSTPSPPPGQRPKSTLRSASHSPPPRSASHSPPQVGPPKSNPKVSAPKSNPKVASTKSTPKRNGQGLTASQLAERNGHEDIAALLKVEDAVFPRPAGPSAFIPAHPLDLDRPPTPTETRSISSPFPSPSAALPFLLLLLHLVVCCPFPMPSAALSFLLLLLLLDVCCPSLLLLPPFPSHSVPPSPPRLVPLPLAVSANSNPTPSSQVLLPSLEGHRQESRRPDPPTPPPPAPPALAKSVKSRGSGKLSSSFKLTSKLFSRDSWDGDEETASASEVVASRREVGVSRQRDARAALGKSKSIDAIVETGYDPTSARARDRSIVGWETEIEENREINKKSQKEEEKGKTEPVRVAGPDRLEKQVLEELMKGLIVAGSPGSGNEADTESLMECERSAPGNADDSADDKMSSGNGRKTAVSGPSGGSCSASSSGMPKIDLSASSRSLNRSIQHLVQEDTENRPGHRPPTPARPSLPTLLPGRLLDVSLSASGWDHIRGARGRGPSCTPSEGHVVPLPPINQPRFSEFGVRGREGIRGRGGLGGGEENVLNVAKKTLEQLESNQDEPADPPGDLAHLALAARPRPDTTEAAQAGAEAVARSPRPRGRLNGRAQDRPGQEAAGEGTALWRPDGPRRAVRITHEMAVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH88</accession>
    <name>A0A423SH88_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">(3R)-3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="19">1.1.1.239</ecNumber>
            <ecNumber evidence="4">1.1.1.n12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">17-beta-hydroxysteroid dehydrogenase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="24">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="25">Estradiol 17-beta-dehydrogenase 8</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23">Testosterone 17-beta-dehydrogenase 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">C7M84_018551</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="26 27" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="26">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>17beta-estradiol + NAD(+) = estrone + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16469"/>
            <dbReference type="ChEBI" id="CHEBI:17263"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:24613"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:24614"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>17beta-hydroxy-5alpha-androstan-3-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:41992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15994"/>
            <dbReference type="ChEBI" id="CHEBI:16330"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:41993"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32711"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.n12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:32712"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>testosterone + NAD(+) = androst-4-ene-3,17-dione + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14929"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16422"/>
            <dbReference type="ChEBI" id="CHEBI:17347"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.239"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:14930"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Steroid biosynthesis; estrogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="18">Heterotetramer with CBR4; contains two molecules of HSD17B8 and CBR4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.239" evidence="19"/>
    <dbReference type="EC" id="1.1.1.n12" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003422">
        <property type="protein sequence ID" value="ROT63562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH88"/>
    <dbReference type="STRING" id="6689.A0A423SH88"/>
    <dbReference type="OrthoDB" id="1888931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004303">
        <property type="term" value="F:estradiol 17-beta-dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047035">
        <property type="term" value="F:testosterone dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008210">
        <property type="term" value="P:estrogen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000231">
        <property type="entry name" value="Estradiol 17-beta-dehydrogenase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760:SF83">
        <property type="entry name" value="(3R)-3-HYDROXYACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42760">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00050232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00050435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00052680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00065174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00066822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00070911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00077835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00081419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00081936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00083097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00083258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="ROT63562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="250" mass="26583" checksum="1652E7E7EEA0E131" modified="2019-05-08" version="1">MNALVLTVLGIRVRGGSGIGRAVCQVLARDGARVSVCDINLKSAEETVESMKNPGDHLALCMDVAKKEQVHDGLRVTQEKMKATPTLLVNCAGIGRPAPFLEMTEENFMQVINVNLKGTFLVSQAVCKAMLERGEAKGGAVVNIASITGKTGLANNGQYAASKGGVMAFSKTCAKELAKTGIRVNCLMPGPIRTPMLAFPQQVIDEFLKRNPLGRMGEPEEVAEMAAFLLSEKSSYLLGSCVEVTGGHDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKG9</accession>
    <name>A0A423SKG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative tigger transposable element-derived protein 3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017347</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003201">
        <property type="protein sequence ID" value="ROT64716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKG9"/>
    <dbReference type="OrthoDB" id="9909311at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007889">
        <property type="entry name" value="HTH_Psq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04218">
        <property type="entry name" value="CENP-B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="5">
        <location>
            <begin position="348"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="45"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="137"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="468" mass="53073" checksum="837763FA496A35B2" modified="2019-05-08" version="1">MNQQPYSTASIEMLPDALMTPQHQGQYHNAVVTLGQSPLHTTVSAQHHNVSHEQSPHHSTVASQHHDLTVTHSHSPHQSTIASTHHDTTTVHSQSPHHNTQSQHLETTTLHHQNAHHSCPRQLHAAPVVHSQNSQLTLPLPSQHHDNNQLPVTQTPQEATPTTSQQHIAMLSHGQNTHQTVLDQQSDSIDKTMLETSSPSRDMEEVEEIEEDQASGDGTARHCHTKKSPEQSDDEIKIEYDEEETREELPKKRTRKGRTKSKKKVRSKRSIPAGEVQVETSLTAFMRKRRQDLTLGAKVKVLEMLDMEPKVPQGKIANMFRVSQSQVSRIMKNKDAIMGQWNRFATPDRKRCRLGKAGALEQKLVDWYKQAKKEDLPISGPILMEKAKSIGNEMGIDFKPSAGWLGRWKDRNGVTLKRFKDKDGAPSITKVGNHWRRYLFAKATKEVPLQNVWVIDETEQLRFYSHFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLB0</accession>
    <name>A0A423SLB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003160">
        <property type="protein sequence ID" value="ROT64972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLB0"/>
    <dbReference type="OrthoDB" id="10064156at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051487">
        <property type="entry name" value="Ser/Thr_Proteases_Immune/Dev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24256">
        <property type="entry name" value="TRYPTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="14"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="352" mass="39218" checksum="B204D3DA164418B1" modified="2019-05-08" version="1">MRHRRGVLARSAYAIGHELQALYGEFPWQAAIYKVRNIGGGLQSTFVCSGVLVDKAFVITPAHCVVGPTTDFTVVFGEYTLGGGGSILERQVTGVSDILVYPGYESTNPLVHDVALVQLDRAIAFDNFPQIGLACLPYPDILYRNTGAWDCFTVGWNGKAGALQRVESNLLSKRDCRVYTRAYHEFHAYMRQSPYGYGTSGYDKAHGYHAATYQKHHYYSQSIPDLLCTESFETKACVDDPAAVLVCRHAALHADTFFGFGNRGYRYHAHRGHKRTNARIVNAYGKHRFDSEKWYVMGLSHSLSPCSGKGQGSYRKGYGSQRKDISVFTPVHEYLPFIHAHLDVKQTAAPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLJ4</accession>
    <name>A0A423SLJ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 19">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="13">IMP dehydrogenase</shortName>
            <shortName evidence="13">IMPD</shortName>
            <shortName evidence="13">IMPDH</shortName>
            <ecNumber evidence="13 19">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_016990</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13 19">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="13">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13 19">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13 18">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="13 19"/>
    <dbReference type="EMBL" id="QCYY01003149">
        <property type="protein sequence ID" value="ROT65060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLJ4"/>
    <dbReference type="STRING" id="6689.A0A423SLJ4"/>
    <dbReference type="OrthoDB" id="416622at2759"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000007">
        <property type="entry name" value="Chromosome 19 SCAF14664, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 19" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="5 13 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13 15" id="KW-0520">NAD</keyword>
    <keyword evidence="9 13 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 13 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 13 19" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="20">
        <location>
            <begin position="114"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="20">
        <location>
            <begin position="178"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="13 14">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13 14">
        <location>
            <position position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 15">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 15">
        <location>
            <begin position="323"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="13 16">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="13 16">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="13 16">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="363"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="386"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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        <location>
            <begin position="410"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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        <location>
            <position position="444"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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        <location>
            <position position="499"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
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        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ROT65060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="517" mass="55754" checksum="1C471C4F19B5A2C7" modified="2019-05-08" version="1">MADYLICGGTSYVPEDGNTGAQLFSTGEGLTYHDFIILPGFIDFTAEEVDLTSALTKKISLKAPLVSSPMDTVTESEMAVAMALCGGIGIIHHNCSPETQAQEVMKVKKYKHGFIRDPVCLTPHHRVSDVFDVKKSHGFGGIPITEDGKMGTRLLGIVTSRDIDFLEPNSDKLLSEIMTPFDDLVTAPAGVSLDKANEILQRSKKGKLPITNEHGELVALIARTDLKKSRNFPNASYDANNQLLVGAAIGTRETDKHRLELLVNAGVDVVVLDSSQGNSIYQINLIRYIKNTYPELQIVGGNVVTAAQAKNLIDAGVDGLRVGMGSGSICITQEVMAVGRPQATAVYKVAEYARRFGVPVMADGGIASVGHIIKALALGASTVMMGSMLAGTSEAPGEYFFSNGVRLKKYRGMGSLEAMDRKDTQGAAADRYFHGEGDRIKVAQGVSGSIVDKGSILRFLPYLVCGIQHGCQDIGAKSCSMLRSMMYAGELKFEKRTVSAQREGNVHSLFNYEKRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SM35</accession>
    <name>A0A423SM35_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003100">
        <property type="protein sequence ID" value="ROT65325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SM35"/>
    <dbReference type="STRING" id="6689.A0A423SM35"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="571" mass="61477" checksum="E650CACA0C475C9E" modified="2019-05-08" version="1">MRQLVYPFSAQPLHLLTSLPSFSPLSSSLSHTLSHHLHILSSLLPPSPSHSSPVFFSISSSILSSSNIFLLFPSSISPSPCSVFFPSLLSLYSFFSPPLFFPILSSSLPPPLLPCSSSLLPSFPPPSLLLSSPSSPPPSPSPYPLSPLSSPLFSIPFSHLPSLSHPPPPLPLLHSLFPSSPSYPSLPSSIPFPILSSSHPPPLLPSSTLLLSSLSPPFPFSPSPPPPFSPPSFSPSPSHPPSYPLPPPFLLPSSPPPPLPSTPFPPFSTPSLHPPPFPPLRPRPPTHIQVCLLFTRRCSGTHIRRQRTRRLIFSLDEATCILSSLLPSLFRLLLSFSLSPPSLLLLVLPSFAFSSLSFSFFLLYSYYILIFSFFVSESLSPSRFYPLPSFYLPHFPAIPSFVSLSPLFLLFLNSLLLLSLLPPPPNSSSFSPPPSSLSPTFPPLLPSPPTFFPLPPPSPPPLPPLPSLPPSHSFSHPSLSSPPPPLPLPSPPSPSSPPLPPSFLLPPLPPPPFFSAPSGGENAHLPRRFPIPGLSRIFPASFTWRPSSYPSFLPSSCACVSPRSPQLVKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMT4</accession>
    <name>A0A423SMT4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003069">
        <property type="protein sequence ID" value="ROT65565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SMT4"/>
    <dbReference type="OrthoDB" id="6605399at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="895"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1333" mass="120519" checksum="4A37324DB339674A" modified="2019-05-08" version="1">MLEMELAEVEPDLLLEEELAQVELDLPREVQVEPDGGGVGTSGAGFATGGGVGAGGAGFAAQTAVGGAGFATGGAGGAGFATGGGVGTSGAGFATGGAGGAGFATGGGLGAGGAGFATGGAGGAGFATGGGVGTGGAGFATGGAGGAGFAAHTAGGVGAGGPGFAAQTAVGGAGFAAGGGAGGGVGVHQIGGGAGGTSVTVHHTGPGGASLIGQQAGGVGAVVHQTGGGLGAGVTVHQTGGGAGFGVQTGGAAGLGGTRTGGGAFASQQTGGLATSGVHQTGGTSLSFGSGSPGGISVHHSGSPTSAGVTPGPVASALVSGPTFGAGNQVSVGQAGVGGVATGFTGTQGTAAFGGSAQGGFGGLGGVQGGIGFGAGQGAGVGATQGVGFGGQGAGVGGFAGSAQGGIGFGGGREAGFGATQVSIGGSHGAGFGGGTAAPGFAGAQGGVGFESGQGAIGFGSTQSGVGFGTTQISVGGAQGSGFGTTSAQALTSGFGGGVSVTPSSVTPTASPFVSTPSPVSHSVTPPGVTPASPFLSSTGFSVTPSSVSPTASPLVSVSVTPHSVTPTPFTPGPGGVSVTPHSVTPAPFTPGPGGVSVTPHSVTPAPFTPGPGGVSVTPHSVTPAPFTPGSGGGFSVTPSITPIIPTESPFVSSTHFSVTTPSPPVTGGGFSVTSPSVTPTGSPFVSSTSFSVTPSSITPTASPLVSGGDVGGVSQVSFHSGAASGGFDIPGFSAGIASQGSVPFSNRVDDVAIQAGGIGSGQAGAGFGGQSIGFVGQTTGFGGQEVGFGGPPAGFGGPPAGFGGPPAGFGGPPAGFGGPSRIQGGPPAGFGGPPAGFGGQGFAGGEVGAGFGGQAGAGFGGQEIGFGDQAGFGGGQSFTSGPIASPLVSDPSFGAGQAGPGFDVGPGPGFGAQDAGFGGGQSFTSGPIASPLVSDPSFGAGQAGPGFDVGPGPGFGAQDAGFGGGQSFTSGPIASPLVSDPSFGAGQAGPGFDVGPGPGFGAQDAGFGGGQSFTSGPIASPLVSDPSFGAGQAGPGFDVGPGPGFGGGQGGFVDNQISFGGDPGFIGGQPDLGAGVSFGPVTPEPIFEGGQAGPGFGAGAGFGDAQARFRTDLGFEVGPGFGGGPGLVAGHAGPGFGGGPAEVNFDGTLNIDIGGGPGGAGFAGGQAGFASNQIGIGGGPGFPVGPTASPLIADPSFAASGGQGAAAAFGHSAGGLGAPFDGQFAGPGGGFGFGPGPVANALISAPILSSEQVASQGFIGNQLGSAGVAARSNLAGPTVEFQIGQPLAAATVRGAPATSQAGVLSSLVNANQPALHLIPAQSIIPIGQVAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPD4</accession>
    <name>A0A423SPD4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_015919</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002992">
        <property type="protein sequence ID" value="ROT66086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPD4"/>
    <dbReference type="STRING" id="6689.A0A423SPD4"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000232">
        <property type="entry name" value="Organic cation/carnitine transporter 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF34">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="554"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="37"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT66086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="687" mass="75235" checksum="7E705FE3C782FC6F" modified="2019-05-08" version="1">MANKRSYSSLSPSVEEPQDDEEDYEKAITATGYGFFHYWLVAIGGIANASDAVEILCVSILLPAAECDLHMSSKDKGLLNAGVFMGMMVGGYIWGSLGDIYGRKNVLVVSLMVNAIAGIVSSFMQGFPLFFTMRFISGLGVGGSIPLVWAYVSEFQPASKRGGALSVIAAFWMVGNILVAVLALAIIPYDIGFVTPSFSYNSWRIFLAVCALPSLIIGIVLIFMPESPMFLLLKGRHEETIEILQKIYEQNTSNPRRSYPVRRVTIANIKMQTVSSGSAWRTLKDICIQSWRQSNALFSRSLLRTTLLMLFINFAIQFGYYGLWLWFPELFNRLQIYYNDHPNDKVSVCDLTDFKGNETVQTSNCNSGDEIVDPQALVNTLITAVAPLPSNLWTIFYMDRLGRKFFLVLSMVLSGGSAFGIYFVKTATDNLILSCVFGAVSTMGFNALDCLGAELFPTHLRSTALAVTLLAARLGAIAGNLVFGSLIDVYCAVPMFMVACLLIVGVSVLLVDLISRLTASSIGRSASSLDRLHHSLFSLLHRTRRLDSLTCRSLSPLHSLSFLLSRLSLHIFCLFSLRVRLSLSLSLSLFFVHLSLFLGVPIVRAGRSALLSFSLVGPSSLFSHSLLFVVLSANSGSLVVSFFLCLGSRALGLGLDWLSLQACRQSHLFTLVSLLHHLSPVLGHLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQ40</accession>
    <name>A0A423SQ40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002956">
        <property type="protein sequence ID" value="ROT66336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQ40"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="716" mass="79671" checksum="4E0C9D67E261E412" modified="2019-05-08" version="1">MLLILFYSVSPFYSSFPVLLIQFSFSSPFLFPFPLLTFPFFFFSLFSLISFYSLFSLFIFPFVLPLSHPLFLFTLPLFLSLFSSSFYYHSSTPSPLSFLHLPSFIHYFILSFPLLFPSPLFYSPFHSLLSFSPLLFLSSSSPHPSFIPSFILSLLLVFLSPRVYLSFHSLPTFPTSPLFLSVSSPDLTFIRSFILSLLFSSSSSPKPFFIHWLPSFFLSPIPVLFIFFSFSSLFPPSLIPLSSSAYYFIHSLSFFFLLSFYIISLFPLLLIHSFILSSFFIIPLSLFPLLLIPSSILSPTSLLFLSASSLLSLPPVSTFSFSPLLPFFPFIPLSLFPLFLINYFILSSPSLLPFYSSLPLPPPPLLIISSSPLLPSFSFILFSLFPPSSPSCIHSFILSPPSLLPFYPSLPLPSFLSLLYALFHSLPSFPFIPLSLFPPSSPSCTRSFILSPPSLLPFYSSLRLPSFLSLLYALFHSLPSFPSSLLFPSPLPPSPPPVSTLFSPPSSLLPFIPLSSSLLPLPPLSTLSFSPLLLPFILLSLFPPSPPSCTHSFILSPPSLHPFIPLSLFPPSLPPVNPLFHSLPSSLFPFSLLSLFLFPPSVPTLSSHSFTSSSLSPSSLLPLPPVPLFILPSPFYSFSPSSLLPLPPLFHHCTSPSFSFNPSPLPSFPSLLYPLFHSLPSFFSLLSFSLPSSSIPYLTFLPRVPTSYKKNVICFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSE2</accession>
    <name>A0A423SSE2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014852</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002849">
        <property type="protein sequence ID" value="ROT67098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSE2"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="471"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="538" mass="60333" checksum="12826A16A3C36B21" modified="2019-05-08" version="1">MPGKPERVTRSKHAGTLSQPSSRAPSPVPSTSVEQMPVIVPCSNPEVRQAVRAMEGEMTLFSEILDKIGALSADIQEIKSQTQDFGERLARQEEATHQQGVETASTTHSSPQRALPTPTPEQAQDSSRDEQIATLRRLLKEKERELEEEKRKSRPRDAVQMYGRNDATCDLPRPLPRSRPSTPEPPPRAFIWETASSQGPSQTVSYVLARETVPHFKGDTSASLPLKRNQEIEGWIRSIENLVKPPTSESFIQAARASCRGPADLIINSPLFDFIRDWDTFKAALRSKFRGTYTAADFYKVLYENRMAAGQAPFDFYQQLEGSVYQGYRDHKEAIGDPSELIRRVFLTGIPPWLRDFLALKEDCPTSQLAETAQRIWNSRNGIRHRESTSRHQSPNDFPGDDSVGRHNYPPRPPRTRDAYAYAVAAEQDEVASPYPAPSRWCEYHRSSYHNTSECRATASGIRPPPRSLTCFRCQRTGHLARECPFPTGQDGRAPSPSGSLTAGSRYYHQYTDGTPRTSDQCGERSRSHGTTSRGTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STP3</accession>
    <name>A0A423STP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative rho GTPase-activating protein 19 isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002801">
        <property type="protein sequence ID" value="ROT67558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STP3"/>
    <dbReference type="STRING" id="6689.A0A423STP3"/>
    <dbReference type="OrthoDB" id="10061772at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14963">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14963:SF7">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="81"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="435"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="649" mass="72907" checksum="8E7D401635A50EC3" modified="2019-05-08" version="1" fragment="single">MNSSEIIDDGEKCIQKLLWRLRHEDATQYNTLVKMHLSFATDLPTDQCDGREQPSGRRWHLTPLIRRLGRSGNGRGVMEGAPLTQEGVCQAFQLIHYLNKDYNITQEGLFRKSGSLTRQQELKNLLNSGGDLNLDYGVYSAHDCASVLKSFLADLPEPLLTEAHYSIHCKIAEMHQSHMSQEQKEAAQSRQIKALRLLFLLLPSENYQLLQDLLILLNRVAAHKEQNLMSAINLGTMFAPHILCPRKMAPNDLQYLSGTLSTSVAFMIENQPQLFKVPLELEYDVRQYWNNKKKMKHQLSKRSMMDAPTNTIFTFIDRELTAQANDKDVTEVALAELYAYVQSLPDSAKKRRLIKQFNHASGSGTPQLNQSFLKRQEARGKRLGDSIKKVMMTPRSRCPIIINSTTSLSNVPIPEEKDSQNTPVADVLRTKENVVEDETSHNSPVIINPTAKLSSPVRPTKPLADSTNLSINTTDSEMNDPEYNKGKAITNRKKRDSEGSCENEGETKLKRWGSSTLRRTLSSASSTGSLFGSFFRHLSTSSLAQLASRLSSTTSLTNPEVQEEEKSDESETEEDGEMNESLSSVFKDYLLSRSILTDNPVDLSTDCLEKGIEEEDKVEIQEIPQTTDSNEENSDDNLVDSAYGESQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STX9</accession>
    <name>A0A423STX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pjchi-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_014270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002785">
        <property type="protein sequence ID" value="ROT67648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STX9"/>
    <dbReference type="STRING" id="6689.A0A423STX9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="5">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT67648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="116" mass="12964" checksum="5FD06078AD4AB415" modified="2019-05-08" version="1">MVCYFGSWAVYRQGLGKFDVEDIDPKICTHAIFGFAGLSFTALKQQNANMKAILAVGGWNEGSAKYSTMAADPARRNRFITSSIDLLKKHGFDGLDMDWEYPTQRGGNPEDYVCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SW12</accession>
    <name>A0A423SW12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002692">
        <property type="protein sequence ID" value="ROT68313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SW12"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="46811" checksum="8D6EB45A3278FD6A" modified="2019-05-08" version="1">MRPANDYRGQVLHLHPWNVPKTQELRRQLQQGDQELSEVRRLAPSVQHTMTRYQDHHQQPPVINGSCFPPQPLPWSRPHIPIPEQQLYPERRHTYDPQTSLPQQFRPRSLPQCPQSPHPSSQLSGTPLSYVFTKETIPHFKGDTFASQPLKKNQAVESWIWTIENIAKPATSEMFIQAARANCRGPAELIINSPLFDSITEWDTFKAALRSKFRGTSTTSDFFLQLEGHVYQGQRDHRKAIGDPSELVKRVFLSGIPAWLQDFLSVKEDGSPTQIAETAQRIWNSRNGIRHSDTSPAEENPYHPNCPPRGRDLYAMPVAAERSSPSYHRSPVRERWCEYHRVRIHGTSECRARAKILDPQSPRRRCYHCRGPGCLVRVCPFRERQGDQAPGTAGRFDPRSTSRGEVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY30</accession>
    <name>A0A423SY30_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY30"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="22362" checksum="7CEC38276BE1FC63" modified="2019-05-08" version="1">MSWNNPVQDSVLPSTNPYGNYTVVDTVPQSMLHMIHSHWYQFPPMNPLWYGLLGFWMVVMGTLSVAGNFVVIWVFMKYQESPNTRQPACRQLGHLRLLHDAYHDSPSSGQRLLGTHGFSVHSSVRSMLSWILLRCVSIWSMSSSLADRYNVIVKGWLCCCLLTPHIIMVECWRTLVVLFTLPGAFLPFPSMEPICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T129</accession>
    <name>A0A423T129_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">HAUS augmin-like complex subunit 3 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_011511</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAUS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002449">
        <property type="protein sequence ID" value="ROT70229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T129"/>
    <dbReference type="STRING" id="6689.A0A423T129"/>
    <dbReference type="OrthoDB" id="2159690at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031023">
        <property type="term" value="P:microtubule organizing center organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026206">
        <property type="entry name" value="HAUS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032733">
        <property type="entry name" value="HAUS3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19378">
        <property type="entry name" value="GOLGIN- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19378:SF0">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14932">
        <property type="entry name" value="HAUS-augmin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02089">
        <property type="entry name" value="HAUSAUGMINL3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 3 N-terminal" evidence="11">
        <location>
            <begin position="31"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT70229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="602" mass="68743" checksum="4DDB576316736809" modified="2019-05-08" version="1">MAAMDGERFVSHLQSLGVPGAERLVGSNFDWLFLTDEGSPLAAFLEWFSANVLPSDILTDEDLLEFEELKSRGEVLTGHQLEEMEACLSGLPTSFNSACEPDGQQDMLSQEERERLESQLEVLSMRKDQLSAHKMELREDAFRASKSVKAAEASLKSRQESILSTSRQLTHAHSELASTLNKLTDIFITFNKTTEDEAKFMSQLDFEKWCDEEAKFTNKLKTYIKRQFREGIGEIAGIGDTSEYCLLDVDHLDLHLVRGSGKAEYAQNVEELNRLNKLLRQTEEWRLEGLLLQARRRAEVEEANHLLAAIHRTQLPSSVPLLQQQGRDASESRMVLKLKREQQQQVLLSLISEVAQLESTRTICGNYQLKCQRQEYFLQKQKIVMDQLLAQVARHDWFNVALDLEHQKIKDILEVAGSINAIVSERDSRYQERMKRFEFLSKHHDETKALGQLPPALITLSQLLPLPTVPYSQEDQKEAPVSGKTLEKQVEMLLRALNSAREQMATARNPQFSVLNRMSMNCALLETGLFGSAGSLGALPLAWLDPAVVERYSNLDEKVWKFKQKLLKLICEHEEKKKILQIEPTVREDFMKWTKNLLKGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T315</accession>
    <name>A0A423T315_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dynamin GTPase</fullName>
            <ecNumber evidence="3">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_010850</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002380">
        <property type="protein sequence ID" value="ROT70831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T315"/>
    <dbReference type="STRING" id="6689.A0A423T315"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000172">
        <property type="entry name" value="Dynamin-1-like protein isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin-type G" evidence="15">
        <location>
            <begin position="351"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT70831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="689" mass="77929" checksum="6046F92D10B16754" modified="2019-05-08" version="1">MGRIMGAWVGVGWALVGVGERVILFSFIVPYSPFLSLPFPSFLPPPISPFLSLPFPLSCPFPFPPFFPPHFPSFLVPSLFLLSCPFPFPLFLLYSLPFSPSLYFPSFLLTLSVYSVFLFLSPHLSTSHPFFSHFPYILCFSFFLPYLSSFLPFLFIQFFLFPFSLYSFHFYLIPPLSSFLPLLFFPNFLIFLSFFPSVSLLPILSSPIFLVFSSFILPLSHSSSLFFPSISLLPILFSLFPFILPFLPSSSLFFPSVYLLSFHFSSSHPLFPHFPYILSFSSIILYLFSFNPFFSHFPYTPFIPIFFLLSLLFFYFSSSNSFFSHFPYIPSIPIFLINKLQDVFNTVGADAIQLPQIVVVGSQSSGKSSVLESLVGRSFLPRGTGIVTRRPLVLQLVYTSHDDNQHRSAEAGTLDLDEWAQFLHARSRIYTDFDDVRKEIEHETDRVAGNGKGICSEPIRLKIFSDKVVNLTVVDLPGLTKVPVGEQPEDIEQQIRDLVLFYIGNPNSIILAVSPANMDMATSESLKLAKEVDPDGRRTLAVITKLDLMDAGTDAIDILCGRVIPVKLGIIGVVNRSQQDIIDNKTIKDALRDEAAFLQRKYPTLANRNGTPYLAKTLNRLLMHHIRDCLPELKTRVTMMMSQFQSLLHSYGDDVQDKAQTLLQIITKFNAAYCQTIEGTARNIETTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T776</accession>
    <name>A0A423T776_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002180">
        <property type="protein sequence ID" value="ROT72302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T776"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="714"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="829"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="855"/>
            <end position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="900" mass="95422" checksum="C63B01713FED45E0" modified="2019-05-08" version="1">MTHTALSLHHHSTPHQLSPSPILSPRGPSTPLSLSPHPLRINSRPPGGLAHRSLSPPPLHSATLAVTNPEPPGALAHASLHHHSTPISPSPILSPREALAHRSLSHHHHSTNPEPPGALAHALSLTPLTPLSPTNPEPPPSTPPPLIRINSQSPILSPGSPSTPLSLSPPPLRKILSPREALAHRSLSPPPLHRINSRPPILSPREALARRSLSHHHSTPHQLSPSPILSPGRPLAHRSLSHQLQLSPSPILSPREALAHRSSLSPPPLRINSRPAPLSPPTPLRINSRHQSEPPEALAHRSLSPPPLHSASTLAVTNPEPPGGLAHRSLSPPHSTPHQLSPSPILSPREALAHRSLSHHHSTPHQLSHRSLSTTTPLRINSRLTNPEPPGGPSTPLSLSTTTPLRINSRRHHPDPREALAHRSLSPPPLHSASTLAVTNPEPREALAHRSLSPPPLHSASTLAVTNPEPPGGPSTPLLSLHHHSTPHQLSPSPILSPREALAHRSLSTTTPLRINSRRPSTPLSLSTTPLRTTLPVTNPEPRSPSTPLSLSTTTPLRTLAVTILSPREALAHRSLSPPPLHSASTLAHTALSLTTTPLRITLASPILSPREALAHRSLSPPPLHSASTLAVTNPEPREALAHRSLSPPPLHSASTLAVTNPEPPGGPSTPLSLSTTTPLRINSRRLAHRFSLHPPLHSEPSPILSPREALAHRSLSPPPLHSASTRPHRSLSPPPPLRAVTNPEPPGGPSTRSLSPPPLHSTHPHHSLSPPPLHSASTLAHTALSLHHHSTPLRSPILSPREALAHHSLSPSTTPLSPILSPREALAHRSLSPTTPPPLAPLSPILSPREAPSTPLSLSATTPLRSTPLSPILSPREALAHRSLSPPPLHSAPLHSHQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8K7</accession>
    <name>A0A423T8K7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002112">
        <property type="protein sequence ID" value="ROT72791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8K7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="41605" checksum="A4E4C5B001E06D6C" modified="2019-05-08" version="1">MRAIRVKLLFLRAGLIGRSRFRVPFPLSPPPPSLTSPDPLLARSPPYSPCHHSFAFPFFLPVFSFYTYPLLPPLPCGSSFPPLRSPPCSSPFSHSPAPLLCNSPLPSSSPLSAFSPFPHSPPLQFLPSPPLSPLNLHRNSSSPPLHSFVSSFLSLFPSFANLHFLPNSALPLLPASLHPNSFFPPLLAPLRNSSCPPLPSFAILSLPRSPPSQFLLSPALLHRNSCSPPLSSSIPALPLSPPPRFLLFPALLLIPSPPAISSSPPLPSFAIHFAIPALPPLPSSSPPAFSSIPSPPLSSSICSSPPQFLSPLPSFAIPLSPRSPQSFLLSPAPLLQFPPFRPLWSGGVIVPSSGAAVVDLPLAALPPLSLPAFPLGTRSPWAPLPPLAQQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9L3</accession>
    <name>A0A423T9L3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9L3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="49614" checksum="7491A615E8B02F35" modified="2019-05-08" version="1">MSTAGLAVVPPMCLALGPPNLKVHHRPATLPRRLRGESLRATSAGNRSGQAAGAPSPSSVRHRCHQHARVTTWVFEEDVSLEVLLEAGGVRAHRTPVGLLPRVGAHVAVAVRGPVEGLAAVRARVHGPQALLAQRLRVRHGQERLATTPEPRTRSPLPDLPGGEQQLPRRETAFRPPSVRPPSRLTRSPQQGAHGIPASPSAAATPPLPPSIPVSHTSSHSSKKVETRVPPHVRRLRGTVRAQQTLVGFLPRVRPPVLGEVALVAELLVTKVAAEPPVGHAADAAAEGLLPREQRGTRASATPASRLRFEPLACTAHPTIQPATLSPYERNPEYSQPALQQKATHWGCQSRLTESPVAFSLAFVFTTLKHNDLAPGIPNGYTSLPDLSDPHSTDLPPLSLLSPLPFAPPSLQSPLPPPLPSAVVHHITGRGTFLSYITDSQLVYEISHSFSTRETPSQEATGCGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCY4</accession>
    <name>A0A423TCY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001910">
        <property type="protein sequence ID" value="ROT74319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCY4"/>
    <dbReference type="OrthoDB" id="6353749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="236" mass="25840" checksum="08F40A861365B3F5" modified="2019-05-08" version="1">MGVASPLEHPIIQTNIKVGQDASEHNHLEATTIMSTMKTLVISLLCVLVTAEQKREAEPGFGIGHPFIRPYGIGYGYSSAITHHPFGSHSSVQSYNHLVKKREAEPGFGIGYPLIRPYGIGYGYSSAITHHPFGSHSSVQSYNHLVKKREAEPGFGIGHPFIRPYGIGYGYSSAITHHPFGSHSSVQSYNHLIKKRDAEADPSFPGLLGYASLQYPGYGLGYKYSHASLPLHYGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEV1</accession>
    <name>A0A423TEV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001821">
        <property type="protein sequence ID" value="ROT75010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEV1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019498752" evidence="1">
        <location>
            <begin position="23"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="43837" checksum="9D9EA10902438450" modified="2019-05-08" version="1">MASCISHPRALFTLLDLSLVHSSPHLVHSPSCTLHDLSLVHSSDLSLVHFSPSCTLTLLDLSLVHSSHFSTSASCISHPRALFTFSTSASCTRSRPQPRAFLTLVHSSRFSTSASLVHSSHFSTSASCISHPRAHASRPQPRALLTLLDLSLVHSSRFSTSPSCTPHPRTLLTLFDLTLMHSSRFSTSPSCTLHPSRPQPRALLTLLDLTLVHFSPSCTLHPSRPQPRALFTLFDLTLVHFSPFSTSPSCTLHAFRPHPRAFLTPLDLTLVHSSRFSTSPSCTPHTSRHSPSFISLTSRPHSHSLSSLLDLTLIHFSRFSTSPFLTSPSCTLHPSPHFHALLTLKRHQPPALFTLLDTPPHAPFTLSPTPISRPHPSSIYYTISIIRLSTIVTLNCIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THA3</accession>
    <name>A0A423THA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative photoreceptor-specific nuclear receptor isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_005606</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001725">
        <property type="protein sequence ID" value="ROT75836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THA3"/>
    <dbReference type="STRING" id="6689.A0A423THA3"/>
    <dbReference type="OrthoDB" id="5774777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000028">
        <property type="entry name" value="Nuclear receptor subfamily 2, group E, member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050274">
        <property type="entry name" value="Nuclear_hormone_rcpt_NR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001628">
        <property type="entry name" value="Znf_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24083">
        <property type="entry name" value="NUCLEAR HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00105">
        <property type="entry name" value="zf-C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00047">
        <property type="entry name" value="STROIDFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00399">
        <property type="entry name" value="ZnF_C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00031">
        <property type="entry name" value="NUCLEAR_REC_DBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51030">
        <property type="entry name" value="NUCLEAR_REC_DBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nuclear receptor" evidence="11">
        <location>
            <begin position="117"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT75836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="23742" checksum="69ABA0996461A7E1" modified="2019-05-08" version="1">MTQPGEAAIQPAPLPGEQTTTSFPARLPAAPAAAQEGRRPPRSPSASPPAAHAPMITPAPFPPPSLAMHHHQMSSSLLGGRLSPLGGAGRCATSLPSGVCVSSSGMGASMGGSTMATVSCLVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGACVVDKAHRNQCQACRLKKCLQMGMNKDAVQNERQPRNTATIRPEAFAEMDQERLLREAAVAVGVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THL9</accession>
    <name>A0A423THL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001716">
        <property type="protein sequence ID" value="ROT75895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THL9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019270759" evidence="3">
        <location>
            <begin position="22"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="639" mass="72467" checksum="3DC4F211D9CCD647" modified="2019-05-08" version="1">MIFHIFHIVLLLIHFLPLLRIHILQNIIHSLILHPPHHHRFLRRIPPPSPIWTSRKQPEWRSECPSWPRGSTVFHNVLLLLIVIHMLVFLNILIHIPLPRTYNPPPPPPHLHPFSHHSTSPPPPISGLILQVTTQVEERVSTHTLPPPPHPSPPSPHPSPPFSFTLSPPSRNPIFHNVLLLLTPTLFLLFRYMLLLLSFVIHTPFLLLLLIHIPLLLRHIPSSSSSTSLSPPHPFSSPLLLHILLKPPFPSRSQPSGGAGVLHGHSLPQRSIIPHPLPPFPPHAPLTQLRHPDTLPPFHHPYTLPPSPPLLLRHNLLFLLLLHIPLSLHILLLLLHILLKPPFPLQVATRVEERVSFMATVFHNVPIIHILFLLFLHMLLLFNFIIHIPLLLCHILLLPTSLFSFATSFTSALLLHILLKTSFPLQVATRVEERVSFMATVFHNVLPQRLERYDYSYTYEYGSLDFCVAMPGLRPQWQSLYYPLSDLVWLCVLLVLGLVLASLLALIRLDWEDKKSSTTGFGRVAETVFGILMWQSVVLNAVRNNGTRVLVMAWMLSPSSWHGLSGATSPRPHAAQVPAAGRDAPAAGQHVRERFNASQRTEFIKFFKQSDSGVYKALAERMHIVPSVMEGLQQATERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKP8</accession>
    <name>A0A423TKP8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001576">
        <property type="protein sequence ID" value="ROT77024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKP8"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF41">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018813744" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="20"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="352" mass="40832" checksum="3585DD592C646A21" modified="2019-05-08" version="1">MISLRTLLVVFNLFFVAVGDEHTHTYKDLEEVVLWMNTVGPYHNRQETYSYFSLPFCVGPKEKISHYHETLGEALQGVELEFSGLDIDFKTDVAKTVYCEVELDEVRLKTFVYAVKNHYWYQMYIDDLPIWGIVGEIDEANDAYYIWTHKKFDLGYNGNQIVDVNLTSESRQKLELGAKIKFTYEVNWKKSGVKFEDRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEEMDDMERDLGDEYGWKQVHGDVFRPPSHPMLFSALVGSGYQMLTVTFLVILLAIVGELYTERGSMVSIAIFIYAATSPVNGYFGGSLYARMGGECSVFGLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TL29</accession>
    <name>A0A423TL29_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Alanine--glyoxylate aminotransferase 2-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004193</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001562">
        <property type="protein sequence ID" value="ROT77164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TL29"/>
    <dbReference type="STRING" id="6689.A0A423TL29"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45688">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45688:SF13">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="471"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="501" mass="55482" checksum="353E95AF2A380785" modified="2019-05-08" version="1">MCPQIELAGARGVQYPLRLREVWVKLDGRQGSGTMSVKQKLTKEETLQLRKKHIGPSCKLFFRSDPLKIVRAAGCYMYDEKGCRYLDCINNVCHVGHCHPQVVSAAVEQMSVLNTNSRFLHDNLVLYAERLTSLFPEKLNVCFFVNSGSEANDLAIRLARTHTGKKDVITLDHAYHGHVTSLIDISPYKFNHPGGEGQRDWVHVAPVPDVYRGKYTDKDFTVEECTKKYADEVKQLCDKATKLHGGVSIFFAESMQSCGGQIVYPPGYLRQVYSHVRAAGGVCLADEVQVGFGRVGSHMWAFQTQGDDIVPDIVTLGKPMGNGHPVSAVITTREIAESFGATGMEYFNTFGGNPVSAAIANAVLDAIEKENLLDNATKIGNFLKQEFNRLKGKHAIIGDVRGEGMFLGVDLEQYVLLSNDGPYRNVLKFKSPMVFGMEDAKELVEKLDAIMTEMEAAENIVTNGMEKLMVNGNHDPRQQQQLTNGHANNNIDAPSEIQVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLI4</accession>
    <name>A0A423TLI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sodium/calcium exchanger</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_004058</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001540">
        <property type="protein sequence ID" value="ROT77311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLI4"/>
    <dbReference type="OrthoDB" id="418484at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098794">
        <property type="term" value="C:postsynapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042383">
        <property type="term" value="C:sarcolemma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005432">
        <property type="term" value="F:calcium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051171">
        <property type="entry name" value="CaCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004836">
        <property type="entry name" value="Na_Ca_Ex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878:SF65">
        <property type="entry name" value="NA_CA-EXCHANGE PROTEIN, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11878">
        <property type="entry name" value="SODIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01259">
        <property type="entry name" value="NACAEXCHNGR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019424016" evidence="10">
        <location>
            <begin position="21"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="26"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT77311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="20961" checksum="4BC5297ADC9E9F49" modified="2019-05-08" version="1">MHFVTVFWKILFAFIPPTDIAKGYPTFIISILGIGLLTAFIGDFASHFGCSIGLKDSVTAIAFVALGTSVPDTFASKVAAQQDPYADASVGNVTGSNAVNVFLGIGIAWTLAAIYHNVQGRDFEVLPGNLAFSVTLFCVEAAVAIMVMMIRRHPSVGGELGGPRIPKIVTSAFLAFLWVFYVFMSSLEAYDIIPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNP3</accession>
    <name>A0A423TNP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative polyubiquitin isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001442">
        <property type="protein sequence ID" value="ROT78061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNP3"/>
    <dbReference type="STRING" id="6689.A0A423TNP3"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000160">
        <property type="entry name" value="Polyubiquitin-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019322438" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="34"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="100"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="192" mass="21337" checksum="963FFEA68B9C011C" modified="2019-05-08" version="1">MISFTSALLSECLRLVGVLAVHSLCGASSVADTMIIYVKTLTGKTLTIEVTPQDTVEVLKAKIQDIEGVPIDQQRLIFSGNQLEDERTLEDFNISSESVLHLILRLRGGGIPMFFLNVAMPSCSVIQQVVNEQTTVSEVRKLLEKDPSLKGRKYRLMVAQQEMDSSKTLEYYGITSEAVVRLEFIEDSCCVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQV8</accession>
    <name>A0A423TQV8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001327">
        <property type="protein sequence ID" value="ROT78837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQV8"/>
    <dbReference type="OrthoDB" id="6434680at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331:SF1">
        <property type="entry name" value="GAG-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47331">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="825" mass="92960" checksum="81E15754769221F5" modified="2019-05-08" version="1">MVDNRSNKSVGTSHSCKSSRSEISVAEEELERLQFIKEQNEHAREEERRIFELQQRIRRMKTSSEPARSRPGSSCGDSREDERHPRPHSFNNMCSNWIATSVEPHHKSGNLDPQVSRESEVNVTAGPVHFAVNAAIVPETPLPKWSTPVNPVLNGANIEAMISPAMISRPLNMDEVAQMVCAMNQSVLTQQEQARISLLPPVKLERFDGDFRNSLSSVGHLNGMLRATLNDPRRRLTQLYNQLDGPPKDLIEGCLHLPPDHGYDEAWRMLREEYENSSELLESFISKLFAWKDIEVGDAEGLKKYGSYLFNVEMALGDNICRMELRETISKIVGKLPRYLRTKWASRCVDPGTKSASSFSALVKFVKDQARVAEEIRYIEAGRAKSFAPSRKYKRSPTGSVEVFSNENIPDCYEKLGTPSSSTGGGIEAKGSVTPSVNSPLTDALPCANILDCEPDGRIMMKILPVRVNNSVSTYAFIDGGAAPTLAARSLIQRLGIQGLPVRQAMKTENGIFMCNERVPLMLSSIGGGNNITVNEVYITDKLSITTDSMMPVNWTKKWLHLNDVDLQRLPGDNQEVELIIGLNSILNRHILDQRHGTDDEPSAYLTRFGWVVFGPTGPRNPLTAPVYHISPTQDLGECLREHFNADFWEKEVHSQREDSLEDKLFSDKISQSIHQESGKYVVKLPFRDSSPLPNNREMAVRRMKSLKRKLESDKTFKETYITQMEKNISKQYAEIVPPSGLERNDGRIWYMPHHAVRHPTKLKVRVVYDLKAKFNGTSLNDHLLQGPDLTNPLIGVLMRFRHGHYAVTADIEEMFYQVKVPLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT52</accession>
    <name>A0A423TT52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative homeobox protein slou</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001648</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001214">
        <property type="protein sequence ID" value="ROT79633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT52"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050394">
        <property type="entry name" value="Homeobox_NK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340">
        <property type="entry name" value="HOMEOBOX PROTEIN NKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24340:SF37">
        <property type="entry name" value="HOMEOBOX PROTEIN SLOU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="197"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="199"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="303"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="39153" checksum="71B2AF9507965484" modified="2019-05-08" version="1">MDSRSISPDSVLPRAQNATLAPLPPSTTSPMDLSYPVVSKLTASSLRHCASANSSATCSSAASARSTHDSETTSTTSSSSSAAEASALSPAATTESQQSPPGEEPPGLHRDTNTHSCKPHGARHTPFSVVDILDPNKFVGRVQVTSSEVTSSIDDSQLHAAASAACGELTLGACIADAASPATNGDGLPSADSDSELSPRRARTAFTYEQLVALENKFKHTRYLSVCERLNLALALNLTETQVKIWFQNRRTKWKKQNPGCDVNTPTQPPSPPDMLSYPGGFLPHPGPPLLCPRRWPTSGPRAAHHHLLPRPGRPHRSLPPPPQELTHLTPLVTPAPLVAGASGTSCSSGIGRARARCVRRAPPAGASAGRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU74</accession>
    <name>A0A423TU74_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">cardiolipin synthase (CMP-forming)</fullName>
            <ecNumber evidence="13">2.7.8.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_001290</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="EC" id="2.7.8.41"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.41" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01001168">
        <property type="protein sequence ID" value="ROT79982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU74"/>
    <dbReference type="STRING" id="6689.A0A423TU74"/>
    <dbReference type="OrthoDB" id="10020554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043337">
        <property type="term" value="F:cardiolipin synthase (CMP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1760:FF:000005">
        <property type="entry name" value="Cardiolipin synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050324">
        <property type="entry name" value="CDP-alcohol_PTase-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269:SF60">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE (CMP-FORMING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14269">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT79982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="43881" checksum="446A792BB614568B" modified="2019-05-08" version="1">MAAYMTSSALAKTILQNERFAHSLLRHNIQRNIQQRRKTRATFPASLPALSCFHPSQTDVQSLSWREYHSLREPRNILSKAHVSRTFLSPLNHLGHQFLSHQTRDEVSFWRYACIKHPCQIRCLQTGDASREAGETREQSPPVATWEAVREKKNQFKEAGQDLLDDIKEKKAKVRERMDAIIERENIWTIPNLLCVSRIAFSPYLCHLVLSADYNWALGLFMFAGFTDLLDGWIARTFPSQASRLGSFLDPLADKVLVALLFLSLTYVGLIPLPLTGLIIYRDVLIIGGASYVRYKSLPPPKTISRYFDATHATAQLAPTTISKVNTAIQLSLITASLAAPVFSFSDHYLLTGLCWVTAATTLSSGISYIFSRNTYKILEKMKEESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVU3</accession>
    <name>A0A423TVU3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like-conjugating enzyme ATG3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Autophagy-related protein 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_000704</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001108">
        <property type="protein sequence ID" value="ROT80571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVU3"/>
    <dbReference type="STRING" id="6689.A0A423TVU3"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.50:FF:000001">
        <property type="entry name" value="Autophagy-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT80571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="17468" checksum="394ACD92369BEC4B" modified="2019-05-08" version="1">MLEQEDPSSIQTPRTVPAVSSPGNSTSDGGEVLQTRTYDLHITYDKYYQTPRLWLTGYDENRQPLTVEEMYEDFSQDHANKTVTMETHPHLPGPPMASVHPCRHAETMKKICETVLEGGGELGVHLYLIVFLKFVQAIIPTIEYDYTHNFTLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW12</accession>
    <name>A0A423TW12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MRECK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001095">
        <property type="protein sequence ID" value="ROT80653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW12"/>
    <dbReference type="STRING" id="6689.A0A423TW12"/>
    <dbReference type="OrthoDB" id="5956770at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008191">
        <property type="term" value="F:metalloendopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056978">
        <property type="entry name" value="CC4_RECK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056979">
        <property type="entry name" value="FZ_RECK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039016">
        <property type="entry name" value="RECK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13487:SF3">
        <property type="entry name" value="REVERSION-INDUCING CYSTEINE-RICH PROTEIN WITH KAZAL MOTIFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13487">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23332">
        <property type="entry name" value="CC4_RECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23298">
        <property type="entry name" value="FZ_RECK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reversion-inducing cysteine-rich protein with Kazal CC4" evidence="3">
        <location>
            <begin position="25"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Reversion-inducing cysteine-rich protein with Kazal frizzled-like" evidence="2">
        <location>
            <begin position="78"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="43708" checksum="E196F41484B2D837" modified="2019-05-08" version="1">MPVPPQRLRQPAHETGLPPGAPGLDAAKLGCCRLGSSPECRGLCGRAFSREWGRAWDALHSACLARPQEAALAACLAEADAPCQQGCAGMAFCATFNNRPNALFRSCTPRADDAARKDFQLWQDSLTLTLPGLTAAVPLRGVRAGASGGESAAAAAPCAAPSARPGSPCVTLAPFLAPSAAAARAAVRVPTFPCRPHPCPPRHVCSVNPNHLTPTPRPRMRIPAAHRQSPALILRLPSLPALSSPESARCGRVCECAREGVLQGCRYLPCVDPAPCLARRAKYGAHSPVSRPLCHTASIYTRPPLHTHTSLDTHTLLPHTPSPSRYTRHPHSHTHTLPHPSPHPHTQPPPPPSPLHTHPLPPQRTPHTHTLSFTPLPPAARQPRRISAFRGQTVTDTGPLFTTIKQPPPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TX03</accession>
    <name>A0A423TX03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transmembrane and ubiquitin-like domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001043">
        <property type="protein sequence ID" value="ROT80975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TX03"/>
    <dbReference type="STRING" id="6689.A0A423TX03"/>
    <dbReference type="OrthoDB" id="161999at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17057">
        <property type="entry name" value="Ubl_TMUB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040352">
        <property type="entry name" value="TMUB1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14557">
        <property type="entry name" value="PROTEIN C7ORF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14557:SF5">
        <property type="entry name" value="UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="292"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="463" mass="51257" checksum="86E440A9A462A067" modified="2019-05-08" version="1">MLSYDGIQDVFTAILVIIIVSVIVALAWLSTNVREQPLVATAVVVFQSERTGENHTESSNEQSQRETQGGSAREGEASAVGLANIVKESENSSVNGEPDMEVPERTDGNSSKGRSDMPESESTEVQNEIKPTPMTSMEADIEPTTNSPVSCTESADVEGQGSETKSPESDVTGQLGSSSTPSQVNRDEQKDSAPEMEVRKRRLQQFMSMGENSSSKGTENHSESPSPLTRDEDSYLHTTNDKGTGHKDDTVLKDSFCNSRIVVENCTSSDKSEQSSALDSEGEEDTRPPGSIRIRLKFLDETQRFVFAQLTEQVGSFKRQHFSIEMDANRRIRLIFNGQLLSQDNSTLAQYGLFDNCVVHCHVSQPQQTSRNANQNESVAHEEEDAYMSGLLAPLLYFVMGMMWYLRYEYGHLFNTMSTVILLFLTALLLFSTYLLYITQNVPESRSTTQVSAHSETETQSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXU3</accession>
    <name>A0A423TXU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative COBW domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_025583</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000998">
        <property type="protein sequence ID" value="ROT81255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXU3"/>
    <dbReference type="STRING" id="6689.A0A423TXU3"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="5">
        <location>
            <begin position="87"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT81255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="20060" checksum="3B51AF7EFD8588B1" modified="2019-05-08" version="1">MRGLRVWLIGRVIDMASVNLTTVSALFNPLERTINSSAEVIQTERCRVDLDKILDLHAYDSFTADSYERTLHSRFVEDLPHLDQKVRTVTVEVEGSMTEDAVDNLVEALLWERTVTSSTGSQVNIYRMKGILSVVGEKTPVMLQAVQELYETEPAGSWPDGCTRSCKLVLIGWFLLCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1L0</accession>
    <name>A0A423U1L0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sialidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000798">
        <property type="protein sequence ID" value="ROT82603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1L0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="43608" checksum="D85F189CB3D19062" modified="2019-05-08" version="1" fragment="single">PLVSQSTRRPQSPSPTVSLPLSQSHSSHSPTRHSPTRRLTSDSPTRLTVPLDSPLVVSQSHSSDSPTRLTVPLVSQSHSSSHSPTRLTVHSSHSPTRRLTVPLVSQSHSSHSPTRLTVSQSHSLSQSQSHSRLTVSSSLVRLVSQSHSSSPLVVSQSLVSHVSQSTRLNSPLVVSQSSHSPTRLVSSHSPTRRLTVPLVSQSHSSQQSHSSHSPTRLTVHFVVTVPLVVSQSSHSPTRLTVPLVSQSHSSSHRPARLTVPLVSQSHSFHSPTRRLTVPLVSQSHSSHSPTRLTVPLVSRLTVPLVSQSHSSHSPTRRLSPTRHSPSSHSPTRPQSHSVSQSHSSHSPTRLTVHSSHSPTRLTVHSSLTVPLVSQSHSSLTVPLVSQSSHSPTRRPTRRLTVPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2F6</accession>
    <name>A0A423U2F6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein pinocchio</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000760">
        <property type="protein sequence ID" value="ROT82903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2F6"/>
    <dbReference type="OrthoDB" id="10062522at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT82903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22659" checksum="2DE6EDED41B9BC1E" modified="2019-05-08" version="1">MGRPHDWLARGGPGGRVSDAESLAGNFSSCCLAVAERGRSSLISGSSVLHHNLSNGCLHPAMSCGMVQTDNYFASSSSWVTRSESSESLSRLDLMTHQYPTHVAEPMMTLEDLRSQYNSCYTCGVSWSDNHVSLDCRECGGYSLERPCPLCDGKCRSSWRRDISMSHSVGKAHWEGECGLSSEDRPAVPSFLQEDVLVQGLEDLTTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U467</accession>
    <name>A0A423U467_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000675">
        <property type="protein sequence ID" value="ROT83505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U467"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="45314" checksum="610059911A5A697A" modified="2019-05-08" version="1">MRHGDSLSEEIYYIAFHRSLSPLLSPFPFPSPFTPAKHLHILTLPLPSLTPLTSDFLLFRSPLYFATQSPSSSIHYPFPSFYSLSIPFFSLPNPLPLFPTSTIHYPIPSFHYSLPNPLLPLFTTQSPPSTIHYPIPSSTIHYQSPPSTIPLSLLHYSLPIPPSTIPPIPSSLFTTNPLHFSLPSFTIHYPILSSSLYHTIHYPIPFFLQSQPIPFFLQSPIPFFLQSTQSPSFSNHNPIPSFLMHYPIPSFLYTPLPNPLLLLLPPSLFEPLSSPLRFLCDRSKDVMTLEEVRREGDEGGQSAARRSIYKWHHGKTGPNSWHRRRGDFHLRSRDPEITHPSSKIPIYLLPNFPIFSSMAYLPPVQPANLAPIADLRAAKFTYQFPLFSFYGLSPPCPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U491</accession>
    <name>A0A423U491_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000674">
        <property type="protein sequence ID" value="ROT83524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U491"/>
    <dbReference type="STRING" id="6689.A0A423U491"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="43296" checksum="75D180871C71D7A5" modified="2019-05-08" version="1">MSSLSRIFPICPSSPLLSLSHIFLSSTSSHFAISLPFPSIAPLSSISPFPSISPSCSIFLSPSISPFSFISLHISHFLHLSPPLPLPPSLLFPPSFLLSPSFLPPPSLSTSPSSSISLHLSLFLYLSPPPPLPPPLSPLSSSLSLSPPSRYYIPEGRCVKTLLISSANIMIAPIFFPPLLPFADNTLATKESTRFPLIRISLYLGSFPPPCLPLFPTAPSLSALLPFLLPPHPSFFVPLLFPLTLSSPFPLPSLSPHPPLLSPSSFPLPHPPLLSPSLPLPSPFPLSSPSPYLPPPPPLTLPSPHTLPSISLPSLSPPPPPLLLPPSPPLTLPSPPSFSLPSSPSPSPFSPLPIPLLSPFPLPSPSFSLPFPSSHPSLSPPFPPAISPPPSAPEEPRINTLHVIRSDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4T5</accession>
    <name>A0A423U4T5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Guanine nucleotide-binding protein G(S) subunit alpha isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_023108</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the G-alpha family. G(s) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000643">
        <property type="protein sequence ID" value="ROT83705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4T5"/>
    <dbReference type="STRING" id="6689.A0A423U4T5"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007191">
        <property type="term" value="P:adenylate cyclase-activating dopamine receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007606">
        <property type="term" value="P:sensory perception of chemical stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:006178">
        <property type="entry name" value="Guanine nucleotide-binding protein G(s) subunit alpha isoforms short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF367">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN G(F) SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="77"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT83705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="20563" checksum="081616C3932CAEAC" modified="2019-05-08" version="1">MSHNEARNVGVCEVPREGAAKVFDGIQTVLFLVSASCFDLVVREDEATNRLQESIKIFQNVWVSRFLKDAGFIVFLNKQDILKDKVVNSKKHIGDYFPNYADYKLDVKDQDPPHEEPKKYKEDGCFIRGPISAFSLFSILSYHLLILPFSPPLPVVLFLLFPCRLSPFSYFPPLPHLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9S3</accession>
    <name>A0A423U9S3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_013879</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000273">
        <property type="protein sequence ID" value="ROT85456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9S3"/>
    <dbReference type="OrthoDB" id="6371319at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10534">
        <property type="entry name" value="PR-SET_PRDM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000450">
        <property type="entry name" value="PR domain zinc finger protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000193">
        <property type="entry name" value="Zinc finger protein 300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001532">
        <property type="entry name" value="Zinc finger protein 483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF49">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21549">
        <property type="entry name" value="PRDM2_PR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13465">
        <property type="entry name" value="zf-H2C2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="217"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT85456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="37891" checksum="EA68FF3BCAA1B9F1" modified="2019-05-08" version="1">MKSTSTDDPKMDTRVLMPAEFSLVVTARPLPPLDRLVPAEDCIKVCATRRLPAQTRYLPFSGTVRADNLPLLPYLPPMDVRSRYGGYDSVDEDGRRTCNWVRFLKVAPFYSHEVNLVGRRAGPRGDVVFEVVQEIQAGGELLAFLLPDMSGENSLLLPALSLIRSASSLQNSAVSPPLAPPKRRERTMLPCSECGKAFDRPSLLKRHIRTHTGEKPHVCDVCGKGFSTSSSLNTHRRIHSGEKPHQCGVCGKRFTASSNLYYHKMTHVKEKPHKCSLCTRSFPTPGDLRSHMFVHNGQWPHKCSVCGKGFSKLTNLRNHALLHSAKARVPPPAAPVSPSSASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBH9</accession>
    <name>A0A423UBH9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative gastrula zinc finger protein XlCGF57.1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_012682</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000026">
        <property type="protein sequence ID" value="ROT86056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6348615at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000340">
        <property type="entry name" value="zinc finger protein 473 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000110">
        <property type="entry name" value="Zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="773"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="801"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="828"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="855"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="912"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="942"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="989"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="1018"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="1048"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="1076"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="584"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1099"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1297"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1431"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="606"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="735"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1301"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1442"/>
            <end position="1457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT86056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1457" mass="159095" checksum="F42236973E140C58" modified="2019-05-08" version="1">MDEGHSVTAGDEVQQRVGAAVPEAEGLSSSGRNVAVGDVDRGVNSHTVLATFPEGDAEGLGSANHIQVQLLDGQVIQITSASIVESEMQESSGVGSRGSGTLRNAISSPRAEGSSGAVTLLTADGKTYILPQPLSSEVETTGGYLITEEVLGTEGGRSSEILQHHPVLTIPSPLAPLPYPTPTGRHPDALAIAASEVFSENYSGLSLEAGNGYEESRAFQIHVKVPEQGFKEQNAEENSQAFSQQRLCTQKEVAEFSDCSIITIHAPNAEERAGEKTMKHYEEATPNDVHERASEQLACRETDHGSHTRKERLLRDIEDGIQQFDSSNYSALYSKLSSEQESRIHVTPIHARAVSRGKKVSCEKAVTEDDSDRKQDEESHEKILEDLQPLSTEVGQSCDSSVGLWATGRREEIPGDAIQADTSSREIWLKGNRDQDFANAMPNLVQVKSYADIDSSRGNRSFTDVLDTHAGRSEIDSHDPQIMNSGNTTDSVQNDINHVPDRAGSCTVANINPNASDDISKPCSAYGNGIHTDPVNPTSAMHSVCTSNEEETEKYSLAEGSFEEADDISSLSDIDTKVRRSARLRKIKEQKKRVPSEDPPQQHQLPEPDAKRSRPAGRSDQKTVFWECDKCDAMFRTKVSRDRHIQEDHVFTCYMCGWQGKNKTKYEVHISTVHCSQQARCLACRKDFQSYEAYKQHMKTAHSVNTDIDIKTEAEERPSGGEPDCSRVSQYEDGSDGKMSKLLSDDGRLEQSDASDSKITLNEDEAFTGYGEKRCPYCGKQFQRRSRLLRHINYHLDNRKFTCEYCTKAFVEKSGLDAHLLTHRPINKSCSECGKVFKTRRTMKRHLKTHQNVVHSCGVCGKQFRHEESLRIHKSVHKDGGSGNVCSLCKKDCKTPYYLQLHITTKHEAAKFTCLQCDRSFKWRQSYGKHMAIFHSNADMQYACPKCPKHFKTASELRLHQVAHSDEKKYHEYTRDKHVKTVHQDKRDHMCPQCGSLFKAKAYLDQHLSQVHTTKERVKCLQCGHDFKTMSNLKSHIKSVHNSRNPKYTCETCNKTFMAPKDLARHTKVHTGVKDYVCPVCRRSFARKDNMVSHMRTHAKESALPPQEPHRDVAPTSIQPQDPSITHILGIPSAMAEARNTQTAVAVSSNSIVLSSIPVSSHNLTLSNIPVSSSIALSNPAVSASSISLPPESTTLSLSSVSSANVILSSVPSSSNSIILSRIPVSANNITQQSLPSSSNALEFSSSGSNNIVFSNTQLPVPSGSMDLTNTHSAPPGCLTLSTVACSEDNVISSETSAPASSLGFSGDTPSSSSSNGSHPVFGLQHHIMAPAQHEGAPMASMASLLPPCSAPGSSGTLSPHMAQQGNAAQMVWSRVGSEQVALAAGVLSLPSPAPPLSTENAQQYAQPGLYTIVGDSSKVTPLENFTLHSVEVAHPSPPAAPTSHQSSHSAAVSEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-07-05" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1W6AKT3</accession>
    <name>A0A1W6AKT3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Casein kinase II subunit alpha</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CK2A</name>
        <name evidence="16" type="ORF">C7M84_010639</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <title>Identification and characterization of casein kinase 2 alpha in Litopenaeus vannamei.</title>
            <authorList>
                <person name="Huang Y."/>
                <person name="Zheng Z."/>
                <person name="Wang F."/>
                <person name="Zhang Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="16 19" key="2">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17" key="4">
        <citation type="submission" date="2021-11" db="EMBL/GenBank/DDBJ databases">
            <title>Molecular cloning and identification of casein kinase 2 in Litopenaeus vannamei.</title>
            <authorList>
                <person name="Zhang S."/>
                <person name="Zheng Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="18" key="5">
        <citation type="journal article" date="2022" name="Fish Shellfish Immunol." volume="124" first="230" last="243">
            <title>Catalytic and regulatory subunits of casein kinase 2 in Penaeus vannamei: Cloning, identification, expression profiles and functional analysis.</title>
            <authorList>
                <person name="Zheng Y."/>
                <person name="Hou C."/>
                <person name="Yuan H."/>
                <person name="Hu N."/>
                <person name="Tan B."/>
                <person name="Zhang S."/>
            </authorList>
            <dbReference type="PubMed" id="35421572"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site. May participate in Wnt signaling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="KY038483">
        <property type="protein sequence ID" value="ARJ31756.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01002348">
        <property type="protein sequence ID" value="ROT71054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="OL411880">
        <property type="protein sequence ID" value="UZH43777.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="OL411881">
        <property type="protein sequence ID" value="UZH43778.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1W6AKT3"/>
    <dbReference type="STRING" id="6689.A0A1W6AKT3"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="7 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="37"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00057837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ARJ31756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT71054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="UZH43777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="UZH43778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="350" mass="41513" checksum="B6530148DE3FCCC5" modified="2017-07-05" version="1">MPLASRARVYADVNSHRPHEYWDYESHVIEWGHQDDYQLVRKLGRGKYSEVFEAVNINNNEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLQAVVKDPVSRTPALVFEHVNNTDFKQLYQTLNDYDIRYYLYELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYEYVEKYQIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQERLTAHEAMEHPYFYPIVKEQGRQMNSPTPAPPGAPLAGVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQ50</accession>
    <name>A0A3R7LQ50_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">14-3-3 protein epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020788</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004168">
        <property type="protein sequence ID" value="ROT61436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQ50"/>
    <dbReference type="STRING" id="6689.A0A3R7LQ50"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000002">
        <property type="entry name" value="14-3-3 protein epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="5">
        <location>
            <begin position="215"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00039427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="49705" checksum="158A2B7FF1BA6D64" modified="2019-04-10" version="1">MVRGAKGGKTSGEKSGWKAGKERERPRRRGSGPPAPSSACEAPRGRPPSSVSECEGTQAPPRPSGTRRRRPWPRAARAPRPPSSSWRGRGRGAPSGVGVRAPCPPRRGREGGSGEGGPSRRREGGARGIDHLAPVGTVGGVVSGSGGARARWPPGGAAGTPGLGAWAPCRRGAGGPAAVAPPGARAARAQVGRRSLPGRATCSGQGAAASSRAPRASSCVSTRGRFQRIKMVDAMKLVASMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEEKLEMIRNYRTQVEKELKDICSDILGLLDKHLIPTASAGESRVFFYKMKGDYHRYLAEFATGNDRKAAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPERACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGEAGEGEQKELLQDVEDQDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTP6</accession>
    <name>A0A3R7LTP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003593">
        <property type="protein sequence ID" value="ROT62618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTP6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="55878" checksum="FBB2D2F4A337081A" modified="2019-04-10" version="1">MSSQRASESSAVGRMSCKFGDTTGCPPSSSSFSFLFSSLFLSALLLFSSFFFFLSLCLLLFFFLSPSFFSLCTSSLFFFLSRCTSLLSFLQIWGYDWPSSFLLSLFSSFSHWLSSFLFSSSFLFSSFLCTSFSLFSNFGDTTGLPPSSFLFSSFFLSIDVSSFLPLFLFSSFFSPYFSYFLFFSPNWEWRLAGFLFLFHPSPFLSSFSLSIGCPPSSSSSLSFSCFFLSLAVPSSSSSSFLFSSFLSSAALLLSFFLSLHTSSLLSFLQIWGYDWLFSSLLFLLSLLFLLSHCTSSLLFLLSFHTSLLSFLQIRGYDWSSSFLFLLPPFSSLPSFSPLAVLLPLPPSSFLSPSFFLSALLFSLFLPKFGDTTAFLLPPFSSLPSFFWLLPPSFLLPLFSSFLLSILLFSLFSKFGNATGCPPYSSPSPFSSRFSLSIGCPPYSPPLFNLLLLLSPLAVLFLFSFFLFFFFFLSATSLLFFSPNLGYDCLTPTTITGFTNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUV3</accession>
    <name>A0A3R7LUV3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003401">
        <property type="protein sequence ID" value="ROT63661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUV3"/>
    <dbReference type="STRING" id="6689.A0A3R7LUV3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="318"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="46480" checksum="122DE53C5FEF518B" modified="2019-04-10" version="1">MARVPGAKALTSRHQSGIEQVRSVKVSSDSVTLFPCVLQRLSRRYQFQTKDLPEFGFSSAGFSCSTGFSSGGFSCSAGFSAGFSCSTGFSSGGFSCSAGFSAGFSCSTGFSSAGFSCSARPPARVEQVSPALQASPQQASPAPQASPQEDSPAPQASPQEDSPAPQASPQEDSGFSAGFSCCRILLLRTLSCSSPQQDSPAPQASPFSCRLLLRRILLLRRLLLRRILLQASPQEDSPAPQASPQQDSPALQDSPAPHASSGFSCSQASPPAPQAGFSCSAGFSSGGFSCSQASPQEDSPALQASPQEDSPAPGFSCSAALLLSPAPQASPQEASPAPQASPASAGFSQEASQGFSSGGFSCSAGFSSAGFSCFSCSAGFSQQDSPAPQASPLSPQQDSPASQASPQQDSPGLRRILLPRRLILRRRLLSAGFSCSAGFSQLASPAPQDSSAPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYD7</accession>
    <name>A0A3R7LYD7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_014006</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002740">
        <property type="protein sequence ID" value="ROT67889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYD7"/>
    <dbReference type="OrthoDB" id="203097at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF28">
        <property type="entry name" value="P3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018629033" evidence="9">
        <location>
            <begin position="40"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="453"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT67889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="491" mass="53224" checksum="9959E4F1A6E69B45" modified="2019-04-10" version="1">MAAVMSGGGATSYLSQMVRKMGVKVTLLMVLLSVGGARAEAPTVMGVQLFVNNTPTEVLDVTEKEAIVVSFQLDALPEDASVEVVVQENSADSFGHVKIWPNRFALKEMAGDLTETFNLTGTFLGFSKLQFLLVAPDGKLRALSNETDIMVQRADKLHDQIFTVTMIILVGIAYINMGCAIDLEIIKRTLKRPVAPVIGLASQYLFMPLTSYTLGYFLFHDSPALWLGLFIIGCSPGGGGSNIWTHVLGGSLDLSVTMTFVSTVVAFGALPMWVYILASTIFQDGNFDYIPYSKMAVMVVGLVLPCAIGVALKKFLPKVAGVLKKLLTPVAVVFIIFASTFGVYVNFYIFYYFTWKVAIVGMALPWLGFLFGAVMAVLCKRQFEEVIAVSIETGIQNTGLAIGVVKFALQKFSPLGDITVVVPVAVATLTPIPLLLALLCKRLYERRRKSKLEGIDGPCENPEDPTASPSSSNLKMTPANSQTPLSRDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZI2</accession>
    <name>A0A3R7LZI2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative PI-PLC X domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002634">
        <property type="protein sequence ID" value="ROT68797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZI2"/>
    <dbReference type="STRING" id="6689.A0A3R7LZI2"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="29384" checksum="208730E13510C1BB" modified="2019-04-10" version="1">MAAPETTKLKCHTQGSHDSFSYSLTPEEELGPDAPGLVSALNSCCPCLARPAILRWSVTQRATTTQQLKHGVRYFDIRVAIRHFLVKHPGEVVFLDFQHLHGLANTDHASLVTLLRNTFSELICPFFHQLNHLSLAYLARFKYQVSVFYNFSLPGLRFLQLPPLPSSPHLVTYNFSSPPRFFSTPLPLTTHTILRKALVFYNLPPPPQFLISTISPPNPTLIGLLVFYSLSQPHSSGLSFLQFLPLLQTGPSFNIIPRPLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0I8</accession>
    <name>A0A3R7M0I8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">C type lectin containing domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_012158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002542">
        <property type="protein sequence ID" value="ROT69623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0I8"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018595093" evidence="3">
        <location>
            <begin position="20"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="4">
        <location>
            <begin position="177"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT69623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="36456" checksum="EF8BEF295115A1C0" modified="2019-04-10" version="1">MEVMKVLLAALLCISQVAATCPESEQIHCGTSDSCTRIRYICDGDNDCGDYSDEESGICRAWRNEYCERGSVRCRRMGDTNCVTISRYCEISDPPCEGDLDMRLCQMLREEKLRPLEEIVLPTEESAVRRSSVEEAERFWERNSLKGQHYPAPPRLPSVLHPRRRPVPVRLLLWKGNWGEARSFCKTIGGDLLTLHDGAEKFHELVHLLREHHITTDFWVGGSLRNETEGWSWVDGAHMELGTPYWTIRSTTDCRPRTYSVGVNSTRVANEGACYHYQQAPHTPAEGHCAALNFENYFYMSDEKCLELKSPLCVHPKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6L1</accession>
    <name>A0A3R7M6L1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6L1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="484" mass="52462" checksum="7BC108C1CAC7EF64" modified="2019-04-10" version="1">MRGRRTGFTPLSHRMPSPLQSTRSKKRKSGPQFRATHHNHTPETPHRPLPQSGPKPKRPETSHPTDPPRRPKTQAKHSQTDAGYSLIEGVDTDFCSVSRGASRRGFSIGPELRFSCNKTATKGERLKACRVSPLCFLSPLSFPSPPSSLPFPPFHSSSAPSSLSLLTYFVIAPLPFRFSNPFCPFIRGDSPSPPPPYRKQYTKTNAPIRHTKQVPLRHLLPPPSSSGTSPSTHLLSSTSYPSRSSSRTSYPSRSPLRHHLLPSRSPPHLLPLQVPPPGTSYPLQVPSAPPTPSRSPSGTSYPLHLLRPTPPGPPPAPPTPSRSPSGTSYPPPPAPPTPSRSSSGTSYPSRSPSGTSYPLQVLLPHLLPLQVPLRHLLPPPVLLPHLLPPPGPLRHLLPPPGPPPAPPTPSRSSSRTSYPSRSPSRTSYPLQVPLRHLLPPPGPPPAPPTPSTPSRTSYPLQVPSYTSYPLQVPPHLHPLRPLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6N5</accession>
    <name>A0A3R7M6N5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative transport protein Sec61 alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_008120</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6N5"/>
    <dbReference type="STRING" id="6689.A0A3R7M6N5"/>
    <dbReference type="OrthoDB" id="420669at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000002">
        <property type="entry name" value="Transport Sec61 subunit alpha isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="13">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT73455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="52459" checksum="A87E1605E8A5D1F3" modified="2019-04-10" version="1">MGIKFLEVIKPFCAVLPEIQKPERRIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWIRVILASNRGTLMELGISPIVTSSLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMMITVGQAILYVMTGMYGDPSDLGAGVCLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPATVNTGRGTEFEGAVIALFHLLATRQDKVRALREAFYRQNLPNLTNLLATVLIFAIVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSNLYIIAQMLAVKFPGNFFVGLLGVWADTGSGGPGRASYPIGGLCYYMSPPESFGHIMEDPFHAVVYITFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEMGSMSTLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6U3</accession>
    <name>A0A3R7M6U3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007979</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002017">
        <property type="protein sequence ID" value="ROT73585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6U3"/>
    <dbReference type="OrthoDB" id="6330626at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="507" mass="58479" checksum="7F267C66DEEAE6AA" modified="2019-04-10" version="1">MVASYLRPPCLTSLAASVVARCLTYEDYEECTHYRWDPVMIWQFELPQRKKKNKRCTERSQIFSLNDVSVPVPQPPWKEMRKFRDWWWNTNLLGRLDSSLRNHIVDAIEQLSWTSNTEEEYVLFLLLRLSVDTSIELGADRFDIPSEWCADLAQVITHLGPYPIQKLCVFHDALGLKPVLTSLIQQSPYLQVLKVNQWAVSNDVMMALGNSCNLLTEFVIPCMQPQVFMSDESLFSCFFNGMTREEVLKCWAQGKKPTLSFKHLRYIDILYWKQTERFIQMISVFYPNVRLCGIDDYTVEDENLDLAQPFLEVGAQVTALRISCRTKNILSERLKCLIDNSSFLRELRIHVDDNFDGADNEHVFEKRLEETGVKLKKLVSQMKSFDSLALRPHDGVDITKAVLPTLHSQGNIITSLHMCYEYAMLNTNTLYQIINLCPKLYRLAVSLRFGEIDEASTAYRTVLHSHTSLHTLVVQDISVEEESIQESAFAKIINDLLNAAPNIEVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAJ3</accession>
    <name>A0A3R7MAJ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003876</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001519">
        <property type="protein sequence ID" value="ROT77468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAJ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018719072" description="Gustatory receptor" evidence="2">
        <location>
            <begin position="17"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="44938" checksum="FF2BE74FEFD2A8DC" modified="2019-04-10" version="1">MRVINWMLGFLRLCGSFPFRGRFPHGTFERSWPLGLWCLVRFVAHGTLQALQLDRRFHVMQVSGSLAGLANSSLTFMKDAVVLTQTLLLATRSSRLVDVLSRMKSLGEECRMGTADFVKDPMFVLTFLLSSGLCIWDMYEYVSMGVYMVSKGQWQWAVLFAMARQTLSFTVLPVVILVMHTVPKFLSLVTLATVPAWHEGPLNLAWHGPKGMQNEAADKGRERGSAARTVSLSNNGPPLDSFFTQVQARLTETEETFFMFVDYIAPVMLLFCAGSVIIFTSLLYLLYEDSAKGTADWFKIYATLAGFLLMVQPCLAADAVNREVNKAQEVFKASPMCKEVPATIASSCWAAPTGKADVKDILSRLEVSVEFDLMGFFSLSRSSVTKMCGIAISYLIICVQFSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAL7</accession>
    <name>A0A3R7MAL7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002285">
        <property type="protein sequence ID" value="ROT71514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAL7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="39977" checksum="F055C22906849E7A" modified="2019-04-10" version="1">MSRNLMLIRPYCYLLPRSLRRVSLLWSIVFLLSFLFYRVSLSSVYRALVYLSLSVLSCVSLLCLSCVSLSSVYRLSSVLPCLCPLHLSTCLSLLCLFVSCLSLCLIVCVSLLCLSLSVYRVSLSSVYRVSLSPLSIVVLSLLLSIVVSLLCYRVSLLCLSCVSLLCLLYSVYRVLSPLSIVSLSSCLSVSLSSVYRVSSRVLSPLSIVSLSSVLSWSLSPLSIRVSLSLSIVVLSPLSIVCLSPLSIVSLSLLCLSCVSLLCLSCLFSPCLFTCSIVCLFSSVLSACLSPLSIVCLSPLSIVCLSPLSYRVSLLCLSCLSPLCLSCVSLLCLSSLSLLCLSCVSLLSLVGGCWMLKPFQSVVTFFSPDIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBA0</accession>
    <name>A0A3R7MBA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative relaxin receptor 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT72010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBA0"/>
    <dbReference type="STRING" id="6689.A0A3R7MBA0"/>
    <dbReference type="OrthoDB" id="1883493at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050328">
        <property type="entry name" value="Dev_Immune_Receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373:SF370">
        <property type="entry name" value="FISH-LIPS, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24373">
        <property type="entry name" value="SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="15452" checksum="74100F68003F1C6D" modified="2019-04-10" version="1">MECTEAGLSSVPLVEALGDLDPAAVTSMDLSNNNLTSVPDNAFAAYPSLQYLRLSGNRISSVSPQAFEGVKLQNLYLDNNQLVGLVAGSLPDTLAELSLEDNFFITIPPAVSLIRDLQLLNLARNKVTHLRNGDLIGNDKLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBE1</accession>
    <name>A0A3R7MBE1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF885 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001547">
        <property type="protein sequence ID" value="ROT77241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBE1"/>
    <dbReference type="OrthoDB" id="5959877at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361:SF2">
        <property type="entry name" value="DUF885 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="GLR0591 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018566656" description="DUF885 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="67058" checksum="87D6E9CCD690FAE0" modified="2019-04-10" version="1">MHVCGMLMVLCVGSFSSTRADLPLVDQLMTDYWDWRISSSPEFASFVGIHDYDDQLDSMTLAEYEHRLAKSHEFLDRVTSILDVNMTLSHADEVNLRILKEEVLTYIDGYPYMGFLLPLSYSEGVHVDFERLVTWMVFETAEDYEKLLGRLDLLPQQLVEVEALMREGVARGVVQHAITMKGVGESLGRFVVETAEESPLWSTFTSFPDGFTEEQIQSLQERARNVITSKVSPAFETLKNYVTQEYVTRPDIAVTSLPDGIQRYDQLLKFHTSTNLGVADIHQLGLDEVTRIEGEMAKVIEELGYDLSVPEFSAMIRNDSNFYLNDADEMMAYFERLSYEVIPPELSKVFVNLPETELQLVARPSPDGTAAFYLTGSYDGSRPGIFYVNTYFYDKQPTYEIMTLSLHEGNPGHHLQGSHSLESSSMPFFRRVMEDRNYYQAPSRFPMNTGFLEGWGLYSESLGFDLGLFGDPYDRYGHYSFEIFRACRLVVDTGIHALGWTRQEAVDFMTQHSALSLKNIENEVDRYITQPGQAVAYKVGQLTISNLRARAAAELGEAFDVRKFHDLVLDSAGPLVLLEEEVNAWIAAGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCF8</accession>
    <name>A0A3R7MCF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002106">
        <property type="protein sequence ID" value="ROT72830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCF8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="656" mass="70075" checksum="7DF0161126510FDC" modified="2019-04-10" version="1">MARVGGAASRRERSRGPQNDLFCGGRDTSAAGAYGDDESSPEDSATRQRIPPSAALRIAMQSRSSQSRSSQSRSSQPQPITSFLVSFPRRPAQKAICPNECPNLSPVCLCCLSVCLLVLLRLLSLPIPLSLFSPSLHLLFSLSLTPIAPSSTTLLSLLYSTKIIPHRYSQHLRYRSPHQPLSTSFLALTSHFPTLLLTHHTSLSSPSPLFSLSPPPSSSLMSTNPCPPLFSAYLATLPPLSSLTTYTSFSSLLSSSFSISSPFPPIVFYSLPSHNLYSLLCPLSSPPCTPPPLPSSTPHSLLPYLLSCPPLSPLLLFSFPLSSISLSLPPSLLLSRHLVISLASLLSHASHKVSSEALSLSLPSPLPLLPPSLLSPPPHRPLLPPISLPFPPSLLAFPPSLSPSPPLPPSPLSLSLTPLISLPPPLSLPPPLSPSPPLSLSFPPCSLSFPSLVDLSLPRVSLPSPQRPSISLPPLSSSCSLPPPSLSLPKALSPCPPTPSHSLHPPSLSSRLPPLISFHPLLSSASFPPLSRSLPPSSSRPSRTLLHRLPFPPLSLRVSPPLSPGPRQGTPLLQHLSPLFSPYAPHRSPSPPSLSTVRSPSYFSSLPPSSRLNIISIDSIAPHCPPFHTYPLSPPPSPQTFREKCNRKWKVVVICM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEJ2</accession>
    <name>A0A3R7MEJ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001219">
        <property type="protein sequence ID" value="ROT79612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEJ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="53571" checksum="FEDF8E23CDB198A5" modified="2019-04-10" version="1">MAYFPHSLIYYLSLFLSLSTLSSLSLLPLLLVSFSPHSPLPHFLIILSDSCPTLFSLSLLHPFPSLVPFFPLVPYPSHSSHTHCLPLFFLSSPLLLPISSFISLPLSLSPIITLSSPHHTSPSLPHASPPPLPPSSTSSLPSFISSPLSPITHFSFIHLSITLLPHSFPPPLSLPHHHTSPSFLIHPPSLFPYHHHSSLIPSFISPSLSPPIIILIPSLPHSFPPSHHHTSPSFPSFISPLSLPPSPHFSLIHLPLLSPHHHTSPAFPSFISLSLSPHFSLIPPHSISPPLFISLSPSSHFSSFSSPPIITLLPHPHSSLSLSLSPPLSPHFSLIPSFISPLSLSPHHHTSPSFPHSSPPSLSLSSPYHHTSPSSSPPSLSPPSHTLSPSIITLLPHHSSLIPLLPHSLIHLPPSSHSPSFPHSSLLLSLPSIIHTSPSFPHSSLPLSLPPIPSFISPSLSPPIITLLPHSLIHLSLSLSPPQAASPTRTPRDFTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFC6</accession>
    <name>A0A3R7MFC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Solute carrier family 22 member 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001840">
        <property type="protein sequence ID" value="ROT74864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFC6"/>
    <dbReference type="OrthoDB" id="6348391at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="27482" checksum="230DB63596DE9E12" modified="2019-04-10" version="1">MTMIVKTIYPPTKTILILLLHHSPTPPHTLAPSPNRTPRLRTITLSLYTNYLLVGAVYFGLSLSGGDLSSDPFLYMVLTGVVELPAYTLVIPLVARYGRRAPVVAFFFMGAVALLALPFVPTGSGESMTLALMGKMSIASAFQILDFYSSELFPTEVRTRGMSTALVMSRVGSTCSPFITDYLGPLYPWAPSAVFGAASVLAGWPPRPAETLHVPLPDTIAHLEEREIRTSGFLRLPVRDPRIPTIYVSQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNS7</accession>
    <name>A0A3R7MNS7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024839</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000898">
        <property type="protein sequence ID" value="ROT81985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNS7"/>
    <dbReference type="STRING" id="6689.A0A3R7MNS7"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT81985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="24342" checksum="9B476299E6594351" modified="2019-04-10" version="1">MGQGRVRFRCLNPDCGAEILEETLWMVTKNTVYASLLVKRQLEEVLKAKIEGLEACPFCDFMAVLDQGNTVFTCMKCKRNSCRLCKKPDHLPEECEDIKEKTAARTHLENKMAEAMIRECSNCKKRFIKLDGCNKMTCSCGAMMCYICRQPVANYDHFNYDPAVDEDPSKCPLWKDSDTIHRSEISKAAEAVKRTMNPGENLQTTLRWHPLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNV6</accession>
    <name>A0A3R7MNV6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lysosomal alpha-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_015581</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002942">
        <property type="protein sequence ID" value="ROT66397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNV6"/>
    <dbReference type="STRING" id="6689.A0A3R7MNV6"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00111">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.110.10">
        <property type="entry name" value="Spasmolytic Protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017957">
        <property type="entry name" value="P_trefoil_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000519">
        <property type="entry name" value="P_trefoil_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044913">
        <property type="entry name" value="P_trefoil_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF131">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 31 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00088">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00018">
        <property type="entry name" value="PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57492">
        <property type="entry name" value="Trefoil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00025">
        <property type="entry name" value="P_TREFOIL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51448">
        <property type="entry name" value="P_TREFOIL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="P-type" evidence="4">
        <location>
            <begin position="142"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT66397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="46741" checksum="1467406A4470466F" modified="2019-04-10" version="1">MVQCQTRKTKKSSEVLFDDDLSPGINVTRDNVKITKTAITVVAGWMLFACMLTILIWGLPNFECGLSFSPFTISIKKLKYIDPHSEGDLLKAKEYQNWVRNWQYGNNISFRKDCGEECLDGNASKEENPQLPLEEPKKVEGSFCVDIPLEMRFDCHPDGSPSESSCVKRGCCWHELQEIPERKVPFPAPRLHRPTHGKALEDLPLNIPYCFYPRDYVGYSVTNFTSAEHGYTGFLERSVASVFPKDSPLLQMDVYFETDTRLRVRITDPFQLRWETPVPIVPQVNKSASNPSYSFHIRNEDGAFTVVRKSSGVPIFDTRGAAPLTFADQFIQLSSMLPSNYIYGLGEHLEGLLLDTYWKRHVLWNLDQIPEPGKNMYGSHPFYLSLEPDGNTHGVFLLNSNAMGEIFSFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQ47</accession>
    <name>A0A3R7MQ47_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002834">
        <property type="protein sequence ID" value="ROT67198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQ47"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21074" checksum="8E195D3483F6CB36" modified="2019-04-10" version="1">MPFFSAPSLLQVSPAADVRRRMTSIRGLRPPPRPAPPRLQRAGNRCPFILAAPSPPPAGVARRQMCGGGMTSIRGSANGVGVGGAAIAIDYLVKIHLPHRKYRPSHPPLFFLLPVVRPLHRSPPNSSLSAGHEGLSDNSSLAVGLLHRMNQIHHMLQQTYIKTAAPSEDLVTRGVMAGGVCFCVRHGLPFLPSRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQT1</accession>
    <name>A0A3R7MQT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ferritin light-chain subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000679">
        <property type="protein sequence ID" value="ROT83472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQT1"/>
    <dbReference type="OrthoDB" id="6363126at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="230" mass="26385" checksum="0FFE8AFDBCB6E969" modified="2019-04-10" version="1">MASFLDLSTLLTLAENAYHTMRILFINICVAVVALVTIRAQSSEANDSSGEQQSNEVQHFLETDEGKKMLNLMNKHLQDSLVYLYTSKQYDSQYWERPGMAKYLKELSDNQWEEGLDTLKKYMQRGGKIDDFRGKVNVNAKGQLHSSKRENKYSKLQQTFNKIHRDSSNKFKLRNRLISKTCTQDAEICHYLEEGLTKEAEKMYEVKQHQIIASGLISTGVGLNLFDASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NU26</accession>
    <name>A0A3R7NU26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_015211</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002896">
        <property type="protein sequence ID" value="ROT66736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NU26"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT66736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="493" mass="52862" checksum="C6D9567877833216" modified="2019-04-10" version="1">MTSAGQEHRRERRLTEAQLLPTNLRRLIPRHRHGRLAAHTFAGLGCADSRRGACLVCGCRGCCDQGRGSPPSRLQLAPSPPNSFTAMSSLIPRATANIIKSVTATRSLYDCHDSQHCHYHHLHASTTRPTASSAKNVARRVWSAGCAGLPCPSVVMPSYNCLYPWPALPCPCPALMPVAMAPVPRTGRFPGTRHLVLAVCEGAGPGGAAGRLPWCRLAVHVLVIIPRTSTGISQTEAPGRHSKYSGWLLSLLPSHRGSLSSLQSSSTPESAAAVLSSPGRSRLCHGASLARRVILEAADVMGAPPSAPQAAFQSPIKTFREFLAAARTAGGAPFLPGPGSWGAVRQRRPCERVTAAGKQPDRSFLVFFFFFSRRSSLSLIRLYEQKVLLKESIVLHVLIPANCHPRTLVLVPLCSCLVLQAFSPPLRAAPHPAPQTFQFIVPTLLFTKPHASATHISPDPIHATQSPDFALNRGCADFGAAVCSRNALTGHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P403</accession>
    <name>A0A3R7P403_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_006678</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001843">
        <property type="protein sequence ID" value="ROT74816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P403"/>
    <dbReference type="OrthoDB" id="10033446at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14978">
        <property type="entry name" value="7tmA_FMRFamide_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053093">
        <property type="entry name" value="GPCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47760">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47760:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="9">
        <location>
            <begin position="178"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="500"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT74816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="529" mass="60021" checksum="FE15D5C1B84BB752" modified="2019-04-10" version="1">MSTSPQLKGTGWLTNMRADRRKQCCTSSLTQVTRQPSSRDGPCPPSRQSSVVCREKRSRMPGVRSHWHWRQVGLYSSIFADCERTEKRSLIPETEKISVFFLPLSESPSSLLTTSLQHDPYGWTFWVATFMDTFFPPPGGSVALGPRENDWQQEQVARTRFIAYGVVAPISVAVGIVGNLFTIILLRQPQFRGVTFTYFLVLALSDLLSLCMVVSMLVHFQHEKTLAFSTAVWYAHFEVFLVNMPMSVSVLVVVFITVDRFYSVCRPTHFTAIHTERCARLAIAGSVAFSVLVWLPTCFLMQPVECVEPKCTPPDNRTWWVVHFNSKLFPEDWYRPYAWVRQALLSFIPIILLVVLNALTMRGFLRLRARRNEMARSSASGSLQLTVSSTAERRHRKEQHLISLLVAVMITFSVTMLPSGIFNAIHTDNPKHETTYEVFRAVGNNLEILSHAINFYMYILCSRTIRVALKNIFRRRRQVSLAGASVSRVLIAVQQLAKNNGRGKTPSAEPTRTAGYADTEELREQANET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P496</accession>
    <name>A0A3R7P496_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Clock</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_021520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004522">
        <property type="protein sequence ID" value="ROT60838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P496"/>
    <dbReference type="STRING" id="6689.A0A3R7P496"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990513">
        <property type="term" value="C:CLOCK-BMAL transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047230">
        <property type="entry name" value="CLOCK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46055">
        <property type="entry name" value="CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46055:SF3">
        <property type="entry name" value="CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14598">
        <property type="entry name" value="PAS_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="83"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="541"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="187"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="379"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT60838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="717" mass="77722" checksum="7C71AFA775F549C0" modified="2019-04-10" version="1">MDGVLDFSCSEAEDSLSLSNCSRSGAGGLFQSSLLHSQLPQESSTKVVFVAIGRMDRPQLVREMMIIEPSKTEFTSRHSLEWKFLFLDHRAPTIIGYLPFEVLGTSGYDYYHVEDLEKVASCHEQLMKTGKGTSCYYRFLTKGQQWIWLQTQYYITYHQWNSKPEFIVCTNTVVSYSDVKAELIKEETSKRSPSELEIHPTEDSGGLATAGPSGAGPSGEQQQSLSEDEASLQPATTPQPGPSHLHPQNLQHQQQHRPPQSPLPSASQAPHPQQIVPLQQEGTVVRLQETGSIAQPMGPASPSSQNSSYTPTQMQQQHLPARGEPPPWPAKTRSVSGNGGLETNLPMKIKCTSKSWAHYSRSSLRKDSSQYSGEGGSNISGTSHTSRVSHGSMQQETNLHFASKSNNKERYYRKIELPPELSRSLSSSRLSGSYEEEKKEDQFMQMMVASPTGSASSHNSGGGYSNIDLQYLSNSGVTQNPATPAVSGTATQVVQVATVPFSPVIPINPMVTNLSVQLPSAPTTEGLRQSLILSPDQRQLQEQLRRKHAELQQQILRQQEELRQVNDQLIMAQYGMSLQNIYKGGVQYTPANSVGNNGSFQSSVAVGSGVGSVIGMGTGSLPVSTALHPGGTVTLATGTLAGTLATQSFVTMSTPSSLQSPTNTVSTINPAQVSVQGIGTGMAVPYQLSQQQAQMLFAQPGGTGQPHQQSPQHQPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P667</accession>
    <name>A0A3R7P667_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001631">
        <property type="protein sequence ID" value="ROT76620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P667"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="43853" checksum="0496505B869775E2" modified="2019-04-10" version="1">MQTARKWARDPEGEGNGRRRRSSRGRERRRSQTGCGGDPRLSRQNCKIKGAQTDVLPEAGCSLIHPGALPPPPTQPTPSPLFTPASFRLPCTSSTNSSHAFAFKRHFPFLLPPLLVLSPLQHRLSLRYPARPCFAAPASSPLFPHCLEQYALFRAPETLPLTTTFPSPSLGHHQFPASPFPFHIHLRTFWRHNIKNTTVIALVGGGLSVLLAAPGGVRGQKDEDLARAGRRSALGGRLRPPPSPRTQRLSLPRDSPPSPFIPRALPLEPFLSRPPAAEEASRGFRTHSPTSTSFALLSRRSPDPAESAGATPVGPVEGWWARGGWARRGGGNDMFSYCTSGGEPGKCSSLREQDALTASSRRTLRRVLEEPQLAVIREHCFPLGRAAAAGGKHQGRPRPSDEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P752</accession>
    <name>A0A3R7P752_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor 2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001538">
        <property type="protein sequence ID" value="ROT77324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P752"/>
    <dbReference type="STRING" id="6689.A0A3R7P752"/>
    <dbReference type="OrthoDB" id="7486196at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="1">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="195" mass="22804" checksum="30A3C572E7C6FCFF" modified="2019-04-10" version="1">MFKNTFQSGFLSILYSIGSKPLQIWDKKVRNGHIKRITDNDIQSLVLEIVGVNVSTTYITCPADPKKTLGIKLPYLVMIVKNLNKYFTFEVQVLDDKNVRRRFRASNYQSTTRVKPFICTMPMRLDEGWNQIVFNLADFVRRAYGTNYVETLRVQIHANCRIRRVYFADRLYSEEELPAEFKLYLPVQTKAKSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE90</accession>
    <name>A0A3R7PE90_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative ATPase family AAA domain-containing protein 3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_023332</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
            <location evidence="2">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000677">
        <property type="protein sequence ID" value="ROT83489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE90"/>
    <dbReference type="STRING" id="6689.A0A3R7PE90"/>
    <dbReference type="OrthoDB" id="199596at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021911">
        <property type="entry name" value="ATAD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075:SF0">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23075">
        <property type="entry name" value="PUTATIVE ATP-ASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12037">
        <property type="entry name" value="ATAD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="353"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="101"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT83489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="557" mass="62189" checksum="8A1CF4D0CCD7144F" modified="2019-04-10" version="1">MSWLFGMNQRPQDFSQFVPPPGASGGDGGPDGPNDRGKGNSSMEAYRFDSAALERAAKAAKDLEKSAFAKEALSLSLMQEETKQKEIMTKAKEMEVQIEAAKAEGKRIEQEERRKTLQEQSKLDQQKSQYQDQLARKRYEDQLAQQQRMNEDNLRRQEESVAKQEAMRKATIEHELEQRHKYDLKRIEAEMTSKAKVDRENQDLTLEQIRVRAAEDRETTLKSMIEKRETILSSIKTAGAAIGTGIDAFLSEPAKIQAAVAGLVALTAGYYGAKGSLGIMFRFMEARLAKPSLVRETSRISAFDVVRHPVQTVKKIQKRPEDVLEGVVLNPSLEERVRDIAIATKNTKFNKGMYRNILLHGPPGTGKTLFAKKLAMHSGMDYAIMTGGDIALLGRESVGAIHKVFDWAGTSRKGLILFIDEAEGFLRKRHENISEELRMAISAFLYRTGTQTDKRLKVAEFDYSGACTKVADLTDGMSGREITNLALDWQMTTYASRDGVFSEEIMLKRAQAAVQHKKHKVSWRSAHETKKTVFSAAVIAAVENANSAPPSKPEPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF20</accession>
    <name>A0A3R7PF20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000528">
        <property type="protein sequence ID" value="ROT84560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF20"/>
    <dbReference type="STRING" id="6689.A0A3R7PF20"/>
    <dbReference type="OrthoDB" id="6357869at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="1">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="31731" checksum="8ACAC0017E66B16E" modified="2019-04-10" version="1">MPRERFEQITRNLHFVSSEAAHLEDDQLWKLRPVIDMFGDVFREVFVPEQNISIDKSLWKFRGRLFFKTYNPSKRARFGLKVYKLSASEGPCAGYTSVFRIYAGKDKGSIPSSQWAVMDLMERGGYIWKGYNMYCDNWYTSPTLFHFLQSRKMGAVGTVRSNWRFMPKDFKVSRKGEVAFRSSATGMLALAWMDSKQVFMLSTIHTSQMATVARRWGPDASKPQCVVDYNAGMKGDLGTSSPAHTLLRKSLKWYKKSFFTCMTLPLSIDMRFLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFA9</accession>
    <name>A0A3R7PFA9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL39</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">39S ribosomal protein L39, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_021312</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the mitochondrion-specific ribosomal protein mL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000446">
        <property type="protein sequence ID" value="ROT85111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFA9"/>
    <dbReference type="STRING" id="6689.A0A3R7PFA9"/>
    <dbReference type="OrthoDB" id="5870821at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000006">
        <property type="entry name" value="39S ribosomal protein L39, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="TGS" evidence="8">
        <location>
            <begin position="55"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00071662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00075914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="336" mass="38231" checksum="C7324AC096199F85" modified="2019-04-10" version="1">MQATPGRLLLRLLENRNHVKRSFYHKQALTNAAVQKKRVELFNKEAKRQAAFITDVEKITVKYCDQPEECTLVMNKNMSTPYNCAQHINQNILERSVLAEIDGQVWDMHRPIEDNCTLRFLHFRQQDPYYVNKAFWRSASIMLGAVLESAFKENLYVELCSFPSPNVRSGSFVYDVDLKIPSWEPTKDELRSLSAEMVKLSMAGHRFERLEVDASLALKMFADNQYKKRQVPFIAAQSSSGNSVVVYKMGNFVEISRGPMISNTGHLGKVSIVGVHPIQTEEGQLFRIQGVALPKGIMLNHFSYGLLEERATQLNSGRFPSIPSLDKPLPNHQARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHB1</accession>
    <name>A0A3R7PHB1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Skeletal muscle actin 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015492</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002928">
        <property type="protein sequence ID" value="ROT66474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHB1"/>
    <dbReference type="STRING" id="6689.A0A3R7PHB1"/>
    <dbReference type="OrthoDB" id="6329647at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41688" checksum="FEC3843A54E7D719" modified="2019-04-10" version="1">MCDDEDTCALVCDNGSGMVKAGFAGDDAPRAVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKVWHHTFFNELRVAPEESPTLLTEAPLNPKANREKMTQIMFETFAMPAMYVAIQAVLSLYASGRTTGLVCDSGDGVSHDVPVYEGFALPHAILRLDLAGRDLTLYLMKILTERGYSFTTTAEREIVRDIKEKLCYIALDFDGEMNTAAASSSIDKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETVYNSIMRCDIDIRKDLFANTVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQAMWVTKEEYEESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIL9</accession>
    <name>A0A3R7PIL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008479</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002064">
        <property type="protein sequence ID" value="ROT73108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIL9"/>
    <dbReference type="STRING" id="6689.A0A3R7PIL9"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042574">
        <property type="term" value="P:retinal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018606354" evidence="6">
        <location>
            <begin position="20"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="557" mass="62140" checksum="1C1C8FEDCF72CE9D" modified="2019-04-10" version="1">MGRSLFSIVILALLTFAHAEPDPPTSSWLRHCEKDTPTPVKGVVEGVVPAWLEGRLTRVGPGARHVGDTSYRHLFDPLALLHLITVQGGEVTYTSKYLDSDAYRANMEANRIVVGGFGTAPFPDPCRTLFDSVASWFSRPPKIMDNCLVNVLQVKDQMVAMTETDEVRVVDPETLDTLGDKLTISEYVAVRQATAHPHVDPDGTVYNLASSGNRNGPTYNIISLRNGEIEQAKMEASINARWRFHPGYMHSYAITENYFILLETPFTFSIGALLAGQYFGKSFEEAMVWFPNEKVHFRVIDRRTGQEHPTTFTSDAFFTFHHINAYETSDDMLVIDVSHIQSGEIVKSLYYSNLKKANDDPTKLKFDSVAKRFILPLGDVSGMPDESELLEGVPDAKVENRAGDSASAKKVSDNTIHLEALTLNPIFFEMPRINYDYNGKQYRYAYGASNEGMVLDFTTLVKLDVKTGEEKVWTDPAYFVSEPVYVASPDSKSSGVEDDGVVLSLLLHRTNPRLISFLVLDAQNFNQIAKVDFEAQGTVTPTFHGQFVSSFDQVHGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNZ2</accession>
    <name>A0A3R7PNZ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Disabled homolog 2-interacting protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002131">
        <property type="protein sequence ID" value="ROT72590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNZ2"/>
    <dbReference type="OrthoDB" id="6158299at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021887">
        <property type="entry name" value="DAB2P_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12004">
        <property type="entry name" value="DAB2P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Disabled homolog 2-interacting protein C-terminal" evidence="2">
        <location>
            <begin position="41"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="123" mass="14266" checksum="81335E062516A0ED" modified="2019-04-10" version="1">MNGEENEQEWKQEAAAAEAEHKEGHEDLKDESTGDEQLSNSRMAHLLAVYQNKVQDSKRVIARLKRQKDSQLQAVISQLLLLEAQLRKEQKGIVSELAQRDHVILAQRQEIDRLRRDNRRLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQ31</accession>
    <name>A0A3R7PQ31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002018">
        <property type="protein sequence ID" value="ROT73544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQ31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="613" mass="66352" checksum="550720D12DA2C6A6" modified="2019-04-10" version="1" fragment="single">MTSRGFRVCLSEVKLRVTLTLLYHLPDLGNTLILLHPPYLLMELPTYLPPTHLPVYPLTRTYPSIHLPTTPSIHHPSTHSPVYPCTYPPTHYPCTHLPACPSSHLPISPSIFNPSIRLPTYHLSYPLTPYPSTLPTYPSTYLSMYPFIHLPTYPPTHLTLSLPPPLTHFSRVSLSPLFWCHTVSDSPPSHLLPPPPPPPHLPLPPPRLSAGDRLSFLRPLSFFRLFCYPSVLSVHPAVPVLLFPILLVFFLLFPILFRPLPPSVSPPLPPWGSPPLPLSPSSYSSLCPSSSCLFSSFRSTSPSLRPSPDSLRPSSSSLPLPLSSPFHPFLFSLPSHPFLFHFLSPPFINSLPPFPLLPSMPFLPSLPLPFSLPSVYHLSSIPSLPSLPLPLSPPLPLPSLFHPILFSLPFLLTLPFLFYFLCPPLPSLPPLPLLLSLPSPSPSFVPLAAPPPCRGDDKTLPRGPDHAPCCVAVVARVTLTSPPSPLHPHRSPFLHFTPPIYLHPPISLLPLHPHPSPSSLPPLPHPSPFTPSSPSPPPFSPFTPTHLPSPQPSPSSPSPPPSPFPPSSPSSPSSPSSPSPLPPPPISPTDSAGSFGSARIAFPLGVTCAGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQM9</accession>
    <name>A0A3R7PQM9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001947">
        <property type="protein sequence ID" value="ROT74057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQM9"/>
    <dbReference type="STRING" id="6689.A0A3R7PQM9"/>
    <dbReference type="OrthoDB" id="6484170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014853">
        <property type="entry name" value="VWF/SSPO/ZAN-like_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37860">
        <property type="entry name" value="AGAP008810-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37860:SF2">
        <property type="entry name" value="VITELLOGENIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08742">
        <property type="entry name" value="C8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00216">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFD" evidence="1">
        <location>
            <begin position="369"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="966" mass="109638" checksum="354F2B842F0B2F2B" modified="2019-04-10" version="1">MPSRREMRLHIFPALPVKSGGIAPSVACPLRPLSPLYLLPHPEERCTKSCLYAERRAIVLYLYRYEQRKKEAARERATVNPARVLLIVNLSGPPYEETRVQGSHVPRVATWLRRKWQAVYDNYKPHILRTFDNVETQAWIFAENLMDWLQKVGLEIKSSAYYQKIAEIVTYVEGIYKDFTEKSKRENLEKYYTMFVEKMKSGFKMLVDGVAPFVQDWIDELQTAWAKLLQYNQIARIKDAVLAAIDKVVWTVRYVDIRGHLIDAAAFILEHGDTIVSQTSIQASQKHIVAKTKFLFTPSQGKVLLVQKLPVDWQAFNVKPNWRDLPEYKNIQWVRDTFFSTSNTTILDKFYKYWNLNFNPVTWVPPFPATGYMIGEQHFMTFDGHHLEFKGRCQHLLVADMVSGQYAVTVNYHSHSSRTIIIYIGGSEIELATDFRVTVDKQPTELPVRVDGATVDRWLHKIEVRTDHGLRINWNLAHDVLSISLSGTSFDKTGGLLGVYNNEPMDDQQLPDGTQTDVVHVLAQGWDVSRGACQSGGNLAVGASKVSVDTCQHLFQSKTSPFKHCFFQVDPTPYLHMCMVDYRSEDRDTCTAATAYMEACSRNNIPVKIPVFCVECVYETDDGETHTLEEGTSTMLEVDDILKSTDVVLLVEDGACNKGFASKKPLNRFESFINAMDEELAKNGLRNVRYAMVLYGGESLYAQPAIATVDNQIFTDASNIHRALDRVEFTAETDSEDYWGADAFEAFNFAADLTFRAGVSVTFVLFPCRSCKPSIPSMDYSTMYHILLEYSITLHVFNDELFDIPKATERSKLYGMDRDNAYTVKDSKRSFTGDQALRRQLTTPKDDLGYCAPLALETGGSIFTMSPIKQSKKRLKKQIEKVAIVFGRRVSLTAKPQSRKRCVCVPSTADGAASVQCDNWDSGQLSILAMYGNLTDMQPDFEMNMDEVGTCQRRDSQGVCVQRIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTL9</accession>
    <name>A0A3R7PTL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000851">
        <property type="protein sequence ID" value="ROT82281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTL9"/>
    <dbReference type="OrthoDB" id="6374889at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="764"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="835" mass="90267" checksum="5E1A7323AE889987" modified="2019-04-10" version="1">MWGGRGGGGGDGMAFSSSPSLFPHFLSSPPSSYSPLTFDLKHPPLLLSFIITYSLLLSSRSRLNHARSTRYTATTGPGTAVTRQSIHGSRRPRPYHKPRPLHLGTPIPKLCHLRRARPFTLTCCRYGQIGTFGKRSNAVNPYLHPSLRPSFFLPILHLCLIDSSPFSPLPLIIPPLPFLHLLPPSIPRLHLHLLPPPALAPSIHLTLTLPSSLPPSILPTSHPLLSHPPLPASLPSLSPQSYLPSPSISPHLSSSPPLTTQCHLPSALFPLHFPTSLYPPSPPPLTSPFPPPSSPRASPNPHPLCPFPPSCLSPSILSFSLSSLPSIPFRLQPSLSISLPFPPPSRLVPSPPSSTFLFPLPFPSTHFLRTLPSLSISPSPLNYVLLLFPFPLHPPSPFTLLALSPLALLPSTHPSFAPSPPSPYPFPPPSSPPRPPPPPPDLILARRAGRGGQTLLRPPGQHLYDAMLAGRSVYDFYDRRHPNAYYDRYFLPDDTSSSETTSLLSYRLHRSCSAHLPRHHSLRKCDMLAPPPYSEVAAKPELYPVVVVRGGMPEVKSTKSMTEGGHVTHTSAHWPAPCHHYIYRSGSVSTPEGSQSSSYTCGATLQSDYGRCRVSSPGCVLALASPASSVGPHNSDVSSLPPTSPPSPPAPTSPTLPPSPATRELRDALHLMDRSLRRHYSPPPRQRARRPLGASLSLDVAAPTRPRSLPLTAVTPSSPPCLNDPPSPLLPASTSTPNLAAAWPSPSGRTMLVAALVDGERVVQRPAMEGDPEPLAPGEGDGEWGRDATDRRFRWRARDRSAERSPSSPKRDAAGFGGRERVQDKPEGQVPKHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PX50</accession>
    <name>A0A3R7PX50_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_001388</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001177">
        <property type="protein sequence ID" value="ROT79910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PX50"/>
    <dbReference type="STRING" id="6689.A0A3R7PX50"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF12">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="597"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT79910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="688" mass="78459" checksum="3360BF3DF607C971" modified="2019-04-10" version="1">MGLCGDTTSPMREEERRPTDVVWLIFFFLFLALLIFIAAFALVYGDPLRLVNGYDSFGNVCGSSNADMADHNDSRMSLSGYDTTDRRYVFFFDVQDLSGSTKVCVKECPDQTLHTFQDIQDFYLRTGSQLCRYDYTKHEEDINKMQSINARQANESLPSPECPSLPVYHSDPVLNRCVPVEGEGPAGLVYNLYGYLNSLDILEQVLADLYASWHLVLIFIFITLGISCVVMLLLHYMAGLVSYAIMIAVMIVSTALTVLLWWSYISVHLQLDNAPLDQILEETVRNERALLIYAIIATIMTVALLALVLYVRPHITMVAELFKHAGACLTRHPGLLLQPVITFFVLLAFFLFWVWVLMSLATAKHLRSSRLQTTLQEVINNNSAILSEGDDTNLTFMRTPQRILEYVDPSWVRSMWWVWVLGLVWVAEFILACQQMIIASAVSTYYFSRQEGRGKVRHPIWWSWRTLLLYHLGTVAKGSLLITLCKLPRLLIQWITKKCKDPEHSCARCGLRLCCCCLWCFEHFLKYMNHNAYTVTATRGTAFCESAKIAWRVVLTNMLQVATVNSIGDLTIFLAKITVTALVCCIALPVLHANPTLHLYAVPLIVTAVFAFFITHCVFSVYEMAVDTLFLCFSDDYNTYDTTDGRELVADKELYEFMVKHEDIDRKNSRKPRRRDPPETIRFKEGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q084</accession>
    <name>A0A3R7Q084_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003121">
        <property type="protein sequence ID" value="ROT65203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q084"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="48457" checksum="0F60AA2616D97B65" modified="2019-04-10" version="1">MTGQPSLNHERRQTPHSPTFRSSPKTSAARGGTETPLVNPTSHPHNILAHPHTSLKIFTHPHTSLKTLTISSYILIYRHPPSRVTTHTTFTPPFPLPHTPFIYARTILTSLIYSHIRPRPHTPFKSPTFPLRRLYPLKTLTPALIPAHATTTASSHTFTHSFQPSRFLRAHPLEESFSVPSWIDLFSPHPLEESFSVPVPVLVSYPYPYIFLPTLNIPFKTPLPLKPPTPTLISTHALTHSFQPPHVLPTRPSEESSSIPAWIDLFSRVLRPQQPRPPGATRRSEALGRKAARFHISPCHCPPPPSPSSLTNTLSPVPCGCDAPKCQGIVTSLRSAMEYPTPLPHLPNPPTSARHPPPLPKPPLTNVMYPSPHPPKGRHTPYPYLPNPRQTIPHPSNTTHLPPIQRQPLLEPPPPTHPRHTPPYPARVSVSAVKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1W5</accession>
    <name>A0A3R7Q1W5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative DNA repair protein XRCC1 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015637</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002955">
        <property type="protein sequence ID" value="ROT66339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1W5"/>
    <dbReference type="STRING" id="6689.A0A3R7Q1W5"/>
    <dbReference type="OrthoDB" id="25840at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000012">
        <property type="term" value="P:single strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17725">
        <property type="entry name" value="BRCT_XRCC1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000008">
        <property type="entry name" value="X-ray repair cross complementing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045080">
        <property type="entry name" value="BRCT_XRCC1_rpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11370:SF5">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11370">
        <property type="entry name" value="DNA-REPAIR PROTEIN XRCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BRCT" evidence="7">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="22693" checksum="4B99EE29E6523731" modified="2019-04-10" version="1">MKDVVFVMSGYQNPQRSNLRDMMLDMGAKYKQDWEPSCTHLICAFTNTPKFLQVKGKGKIVTAKWITDCHKNKIRYPWRRYQLERDRNADESEEEVWAEELLPKEERRAKPNTNTTNDNTATTAIYTNRTMTQQNQQTSTAHTPHLAHANTPSTPPHHAHTPATLPHTCHNHTHRGFPEVIANKITNTMFTANISNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QA98</accession>
    <name>A0A3R7QA98_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chymotrypsin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002123">
        <property type="protein sequence ID" value="ROT72673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QA98"/>
    <dbReference type="STRING" id="6689.A0A3R7QA98"/>
    <dbReference type="OrthoDB" id="5597713at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051333">
        <property type="entry name" value="CLIP_Serine_Protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260:SF132">
        <property type="entry name" value="PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="211" mass="22906" checksum="A007677DCD51EAE2" modified="2019-04-10" version="1">MILTAAHCPFRLNSAQNALNPPSRISVTVGAHYHAQPGTTGGYNVEVDVNNIHLHPQYRLPYDIALLKLVSPLTFSETVKPVCLAPRAWIDDDMAGKEVTLSGWGKTETGSLSSSLREYDTVGYSLPDCISFYGSWMRPTQMCTDGAQRKHTCSGDSGGPVMRIENGKVFQVGVISFGASADCKDQSPDGQVRVAAFIDWFESITGLTFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QEQ4</accession>
    <name>A0A3R7QEQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003152">
        <property type="protein sequence ID" value="ROT65031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QEQ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="446" mass="49687" checksum="58164F6F7BDFA8B5" modified="2019-04-10" version="1">MTNQHMPGGADFSTRVDRLGENACFRALEDATRASLACCPYGIADLSDIRTTDSPPPPPPLLAPRVVRQWDRSTGAPTSVHEPGPGRYLGVSNGQPGRREDLRSDPEDVGVSGRVGVGAGRASLDPPPFLRSTCARSCCLSGKGHFPPPPHLPPTPSHTYPECPSSRRPKRKHDDNQPPSRPFTRPYPYTPNRTRPIGTRPAVSRTRPVPAQPYPTVPPQPYRTQPYQAVPPQRVAVSARTQPSASPVPTQPYPPTRTPHQPYPPNRTRQTVTHPPYHPAVPAQPYAPAVPTHQPYPPRPTRNPPYHPAVTHPTVPATRTHTRRYPTQPYPALTVTHPPYHPTVTHANRTHLHPQPYPPSRTTQYPPYRLAVPTHPLPYPPPYAQQRIHHPVPNPYRPPYPPVYHTPPYRTQPYPSSRTHLAVPTQTRPIQPYPPSQYVYRGSGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHX3</accession>
    <name>A0A3R7QHX3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rotatin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001240">
        <property type="protein sequence ID" value="ROT79469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6343032at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007099">
        <property type="term" value="P:centriole replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010457">
        <property type="term" value="P:centriole-centriole cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032053">
        <property type="term" value="P:ciliary basal body organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030791">
        <property type="entry name" value="Rotatin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029249">
        <property type="entry name" value="Rotatin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31691:SF1">
        <property type="entry name" value="ROTATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14726">
        <property type="entry name" value="RTTN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rotatin N-terminal" evidence="2">
        <location>
            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="1">
        <location>
            <begin position="2177"/>
            <end position="2396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="2412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2412" mass="269201" checksum="057823D010493B57" modified="2019-04-10" version="1" fragment="single">MADVKDYIKKLVHPIAEIRERALNSLLQKVNFQLVASKGLSEHADFLPNLLKLLDLGPHTLRKGVIDLLRFVLTEETARHRFQSLGGIQYLSSLKMVAPLDIVPVISELIQKLQPCYIEEKSEDHIKQFPFRVPRATQVRFASANVAETSTSKDSSFASIIINNNQYIDQAEGNDNVDNSCLCENSEHELPQVTYKSPITFTTFPWQALTSSDRRVLDSTTQSLLSHHEAVVVAALHFLDTVVLKDFPPEVFLQRPAVVQAVYGCVEEEGENAWRVQGPACASLLTLTELLNMRVSHFMDPHLSPRSQQNMTPTSSGMATPCTDMTRGSCCSSLGDHSENIGKGDINIRHKGDGQDWSGSLDSIVHLSSTTVHEADDGDEFILLGMHQIPVTSHCVHIMNVICPLLVSPRPAIQTASLRLLLSCLKLLEHCLEPESLWQSDSDEHDILEAVGGIRRVIRSIAHLLIATFEWRNNARLSTDLEKYVTDTNCLGLLLSNIFKIFVPLEASCQVIDHDVAKSLVSVLCDGGFYIEYSKHHAYLLSHLSKAEPTLAKQVKSITFAAQGLCATSDFLRTSTSHLAQFLELAERSLPVASIHQSTVFVEKLVRGLAKQIALGNVDAEQLTRMRQLLLQVLSYPDDVLRSAGFNCVLKLVEGSIGISQVGDTSLSRSARISILLSPSVIRFLLFSGLVDENDEVVQVTKAILLALFRGKLLMSQTVWGSAVECWRECLLDMQILADADTNLGRAVANLPADIYGHNRTEENFKILKFHLQCLYSKDREIRVQALSHVVHRLAAEITVFVPDPREFHLMTHQDLLINSQPIHLLLKGRISTETGRLAKVVELVMSAGESEVRRAAWSQLAFFLEDPALHQPFLQLCSIQYIVMNFVGMLKYEEALDLTVECIPGAVDVLRLLATHSQDIRQTLARNEELLLCLVRAAHIYYAEERIRGQASCLMALLLFDEIIQLDNIQNRKENEKIIGGKDFIMVPELLPTRLHLPFLCSTYPWHEEQGFCEEVRTLYQVLQEEDWEVMNLLKSVWASVCAGGLENLDGEPGQSANFSDNLQLTTSNVVMLRSSVLKLVISKHLQNTENATSHHEVKKNVNALSFSLLQNRLLWSDTPDCLSTHDWSQSLNRFITGRPNSTVDEQLLTHVLNATSMALMIGGSSQENGNSKFPLLVKLLMNELVNQESALHQTLRVTGAANWVASDPNPRALLSVRLFRTITNLVRQTLKYISGNPSLQDTDEEFSFDKLVESVTTALLPVLKSNDELQNYNLAVLGCTVECVAHVTNTGWPGEEIACQLARGLIRLISTFHVGRGRAHNSYMGRMVTLSSSLALIHLLSHPSGSLTQDIGSWSVEEQGDWSWLVSLWVYRDPVVTSTGLTVATALTIQPQGSKLLHESLTQVSGGVWGAALSYLLASGRSCLVRTLAAQLLINLTEEEPTANSPWRFPVVSDTLTGGSVEGVPALMVLLKHCNFFSVMYLSMAKLWIYQEQPIGNTHDTPNAAWDLSLSRLSSFCAPVSTDDLGASQSEVGSEDYNHNTPSLVSLQLYETLLRLLNNILLLRPSQVILELTSHGIISLVVKQLRYVVSLIQTSEVHLKVVETAMIFLCTVLKYDPTQVLPLARDTSLGHLTLVVLSSGLENTSICMVCLEVLTSLVWAGDWGAAHILEWISVSPVHTLQPVVASLHSTAPLGLQAAAASFVSSLLASVYSSDVTAHHDQEATLANILDVPVRLLNDQDVSPGWELCRHLIQLVCDENEIKDTASNTTTKLKGSHNPEHQHLLLECLKLLLLASEGAREAAHHLRLSFIPFLMRPLSQLTNKIQDINIHITTQLMNKKEIKEDAFLAIQYLEVANNWVKGRGRWIETVGEVLVPLLHQLWTPALRTPPLLTAMLTFMVTASAHHQACLFLTRTSGLPGVALSATRTSRPLLACVTTLVCQQLARLPNYTRGSHIGFKDLPKERFIQSISLLTNCARLQECTLIMNKCDLVSALMKWLDSKQALEDGMTVTGSIVKLMVVLTTHQEVQMSVCKTYGWVGTLRDLILQPSLRIEALLIAANLSRNHLCAQALLSSGNYCHHHLKARIYGASTAISHRDVNRTTHTPLRKTASIQLRRMSSDFPYAIEPLEEKENDAIKKDFTGYLSGAVRVQPRGYFFQGIYRHYAHQYFNLPLKPTDVFVASYPKSGTTWTQELVWLLMHNLDYEGAKESLDDRFPFVEADHVLDPEVFQRPEIKAKLKAVPKPGDRLAQVLKLEEPRCIKTHMPFSLLPPKILDTCKVIYVARDPRDVVVSYYHHHRMWITHGFQGDFKAFFDYFLKEQVMWSPFWEHLREAWERRSHSNLLILTYDQLKEDLPAVIRKVAGFLGKEVSQEETNKLANHLHFDSMKNNPAVNAVADASTGLLDLKEGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLP2</accession>
    <name>A0A3R7QLP2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023893</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000759">
        <property type="protein sequence ID" value="ROT82908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLP2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018620741" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="45"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="182" mass="19962" checksum="A33003C6C6C72D57" modified="2019-04-10" version="1">MKRGWKLVVMLALLLTSAATRGSMTLFKLEHQGQKGTAVIFSRAMLSLTMCASQCAAVPQCRGFNWQRTYSVCEGLSSYEPTLMDANSNVYVPDIHYSWQLLEYSCPTCLGPHFGLSDWVHDCDPATGALVGVAALSSLDDLDYMLCASFHGLDIDHSNGAFFTPSETLRCQGFFSVVCHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNI9</accession>
    <name>A0A3R7QNI9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002070">
        <property type="protein sequence ID" value="ROT73080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNI9"/>
    <dbReference type="OrthoDB" id="118105at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="158" mass="16945" checksum="D8D21648BAC60FA8" modified="2019-04-10" version="1" fragment="single">MIASCFLIGLETSQKPTAGKRTTNMPRKLRSTSSGDKPSVVRKHDDPTSTSQEAGGAPSSRSYSSEPGPSISRQTDAARLRRGSNYSHTGDGKSQTRSFLDLLDESDFSESDDDWLPEAVTSSGRLIGVEEAVTSSDSDSEEDLQEISVSSTAGEPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QT65</accession>
    <name>A0A3R7QT65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-arrestin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001560">
        <property type="protein sequence ID" value="ROT77194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QT65"/>
    <dbReference type="STRING" id="6689.A0A3R7QT65"/>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.840:FF:000003">
        <property type="entry name" value="Kurtz arrestin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017864">
        <property type="entry name" value="Arrestin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF17">
        <property type="entry name" value="KURTZ ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00309">
        <property type="entry name" value="ARRESTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00295">
        <property type="entry name" value="ARRESTINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="197"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="40069" checksum="1201552AD33D302F" modified="2019-04-10" version="1">MEDNSKRQGTRVFKKSSPNGKITVYLGKRDFVDHITHVDPIDGVVLIDPEYLKDRKVFGHVLAAFRYGREDLDVLGLTFRKDLYLASEQIFPLDPNNKRPLTRLQERLIKKLGPNAFPFFFELPPHCPASVTLQPAPGDMGKPCGVDYELKAYVGDTVDDKPHKRNSVRLAIRKVMYAPIKQGEQPSVEVSKEFMMSPNKLHLEASLDKELYYHGETVAVNVHIQNNSNKSVKKIKVSIRQFADICLFSTAQYKCTVAETESEDGCPVGPGFTLSKVLHLTPLLRNNKDKRGLALDGQLKHEDTNLASSSMEGCPVGPGFSISKVFTLTPLLSNNRDKWGLALDGKLKDEDTNLASSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLZ9</accession>
    <name>A0A3R7SLZ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative major facilitator superfamily domain-containing protein 6-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015548</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002936">
        <property type="protein sequence ID" value="ROT66413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLZ9"/>
    <dbReference type="OrthoDB" id="10029266at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="2"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="239" mass="25612" checksum="322AD2C6856B6419" modified="2019-04-10" version="1">MGAQQVTSLVFFLYIFRLLGLSVVGAYGPAWATLLVEFLNGPCYGLGYTAIVVYAAKISPPGTSNTVQSVVNICYESFGYATASLVGGVLYQQFGGPRMYLIFGSVSILVFLLHVLSLRFLPPPEGMSRGWVVLLKGVGCVAEGKVGCGGRVGCVAEGKVGCVADGGRVSEGKKEKGRPLQPRVARWRSNRKRGSDPYTDFPQHAFVRIGGGGIRSESVRRLGVSGEAGRVELVELMRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STU9</accession>
    <name>A0A3R7STU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thrombospondin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006642</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001841">
        <property type="protein sequence ID" value="ROT74835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STU9"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF106">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018564979" evidence="7">
        <location>
            <begin position="19"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="148"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="8">
        <location>
            <begin position="262"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="343"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41062" checksum="46955686B1364C5F" modified="2019-04-10" version="1">MFPLAAALAASLVLVTSAQNGNSYFFECQAEGRFPHPKDCSSYVDCVLSPLGHFLQIKDSCNGGSYNEHLKTCVSDKECKNSFRRGRALISDHTYQHMCSEGNGFLCADCMTMISCVDGVAYSHPCSAGSTCAELEVFGGGVCYPERPEECACPEANTFRVDHYDSKKFFYCNDSWSTPEMFECPEETAFDETTTQCVNKENLPECERSGMFAIASNCSQYYTCIASKDGWIQKALSCDTPDFMYNEASGSCEDPCSWDEGAFSCQAEGRFPDPRDCQRFFECIAVGDGFRVFSRECPAGYHWDSISQGVGLCTKTTDGSSCKAFTPNKCVIPENMCTQGGATGESLVGDGTTPAEETPAPPALRRATRRGNRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZ66</accession>
    <name>A0A3R7SZ66_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pancreatic lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024191</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000792">
        <property type="protein sequence ID" value="ROT82637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZ66"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00707">
        <property type="entry name" value="Pancreat_lipase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.60.20">
        <property type="entry name" value="PLAT/LH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016272">
        <property type="entry name" value="Lipase_LIPH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033906">
        <property type="entry name" value="Lipase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF185">
        <property type="entry name" value="LD47264P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01477">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000865">
        <property type="entry name" value="Lipoprotein_lipase_LIPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00821">
        <property type="entry name" value="TAGLIPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00308">
        <property type="entry name" value="LH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="PLAT" evidence="8">
        <location>
            <begin position="359"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000865-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000865-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="487" mass="54155" checksum="C9389F147B4CD700" modified="2019-04-10" version="1" fragment="single">HPKKNQARKMPAIGATKGAVLFHLLNINLLMDLGAPPPDPVASPAVSSNVEEVCHIVYGQRTCFSMTDPWFSSSRPVVKAPMSPEELGTSFTLFTRLNDTFPAPFKVVTHGYLSYGAVGWIKTMTGELLRSADQNVIVVDWGVGARPPYTQAVANIRMVASQLAYLIYLFNKFADVPVSSVHLIGHSLGAHMSGHTGTYLKKIYGLTLPRITGLDPAEPYFNDTHPVTRLDTTDADFVDIIHTDDSPILGFPLSVGMTQPIGHLDFFPNGGHNQPGCMGDVNCQHRRAITYFTESIRQSCPMIGVACPSYGEFIDGDCWGCDDEHPCSYMGLDAAPLPSQPELTKLYLHTWERSPFCGYHYRVTVEFSNSTEAQEKMGEFGIIHLRLTGNKDKSPPIKLSEKSKYYEAGSVHRRVILTHDIGDLQTMGVTLEYPRSIMSWVRLEKPTFFLESITVEPLGENTKWKYCMAERVQKSGYEYILSSKQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZN1</accession>
    <name>A0A3R7SZN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000717">
        <property type="protein sequence ID" value="ROT83214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZN1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="492"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="625"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
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        <location>
            <begin position="706"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="723"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="823"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="869"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="899" mass="93048" checksum="25528E047E4FA360" modified="2019-04-10" version="1">MIIRLHKRASHLRPATLHHTRQSHKPRHPLQSPSSRNQTSLFIKSHLNTRTTKLFTYKTQPPEQIPQRHSSEPATTTSFTKTNTKPPSSPLIRRPASSDPPPSPQSRPNRLTSPLPPSPVPTPHAHPVSSARPPIKPASSARLSARLLSPPPLPPPPSALLSPPHSPASSARLLSPRLNSPPPQPAPQPASSALALSPPPQPASSAAPLSPPRPPPPQHSPPHQPTSSARLHSPPPQPPPPLARLSAASSARLISPPPQPRLHSPPHQPASSARLHSRLLSPPLQPFFSPPLQPASSARPTAHLLSPPPQPASLSPPPPLQPRPPHQPASTARLHSPPHQPASPASSARPTARLQPASAASSPPPQPASSARLHSPPHQPASSARSSASSARLFSPPATARLISQPPQPPPQPAHQPASSAPLFKPASSTAPSTARSSARLLSPPLQPASTARLLSLTARLHSPPPQARLHSQPPQPASSARLHSPPPPALHSPASSARLLQPARLHSPPSSARLSATARLISLHSPPHQPASSAPPFHSPPPQPASTAASTARLISSASSARLHQPASSALSPPPSRLLSRLSASPLSPPPQPASSARLSSPPARLFSPPSSRPPTASQRLLHQPASSARLSASARLLSPPLQPRLLSPPSTARLLSPPLQPASSARSSPPHQPHQPASSATPSSARLFSPPPQPALLCPPPQPASSARLRPASSARLHSPPHQPPHQPALPPQPPLQPASSARLHSPASSARLHSPLQPASTARLLSPPPQPASSARLLSPLRSPPPQPSFASTASSLPQPASSAHASSAPPHSPPPQPTSSPASSLLSPPSSARLLSPPPSPPPPSPPPQQPLQPASSARLSAARLPPPSAPPPQPASAARLLSPPPQPASSARLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9B3</accession>
    <name>A0A423S9B3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004583">
        <property type="protein sequence ID" value="ROT60747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9B3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="272"/>
            <end position="296"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="502"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="589"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="656"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="732"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="772"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="795"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="844" mass="95779" checksum="6751C9A1CE07FDA7" modified="2019-05-08" version="1">MQLQLTSRGLSGGQRDTRQLKKETLLLYYCFLPLHLFFLFFRLPPSLLYYCFLPLSHLSFLILPSSHFPPLLLFLPSPSLFLILPFFPTSLLLLLFLPFHLLFSILFPSSHFLPLLLFLPLSISFSILPSSPTSPPLLIVSPSPSSFSILPSSPLPPLLLFLPLHLFSILPSPHFPPLLLFLPSPSLFLFFRLPPLPSFIIVSPLSIFFFYSSVFPHFLFYYFVLPLSLFFLFLRLPPTSLLYYCFLPSPSLFLFFRLPPSSFIIVSPSPSLFYSSVFPTSSFIIVSPSPSLFLFFRLPHFPPLLLFLPSPSLFSILPSSPTSLLYYCFSPPPSLFLFFRLPPLPSFIIVSPLSISFLFFRLPPLPSFIIVSPPLHLFSIFRLPPLPSFIIVSPPLISFLFFRLPPLPSFIIVSPPLHLFSFFRLPHFSSFPPLSSFIIVSPLSISFFLFFRLPPLPLYYCFSPLHLFFYSSVFPHFPLLYIVSPSPSLFLFLPSSPHFPPLLLFLPFSISFSILPSSPTFPPLLLFLPLHLFFYSSRLPPLPSFIIVFSPLISFSILPSSPTSLLYYCFSPLHLFFLFFRLPPLPSFIIVSPLSISFSILPSSPTSLLFIVSPSPSLFLFFRLPPSLLLLFLPSPSLFLFFRLPPLPSFIIVSPLSISFFYSPSSPSSLLLFLPSHLFFLFFRLPPLPSFIIVSLPLHPLFLFFRLPPLPSFIIVLPSPSLFLFFRLPTSLLYYCFSPLHLFFYSSVFPHFPPLFCFSPSISFSILPSSPTSSFIIVSPLSISFSILPSSPTSLLYYCFSLSISFSILPSSPTSLLYYCFSLSISFSILPSSPTSLLYYSDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDE0</accession>
    <name>A0A423SDE0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003774">
        <property type="protein sequence ID" value="ROT62195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDE0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="43749" checksum="E0EB621DC7E260FD" modified="2019-05-08" version="1">MALRRLFAYNKKKQVFDDIFREALRKLVGDEPLAKDSVRFQALRKILERSLISRCRYVSLKSHAETFDLAIRGLRKVEENFAILRPISYSSTSLWERIRAKYRFTSYLENTVLVAMKRKLLAFDYDIQTFDGIMCQAVQRLLAGRNLLENSSLAQAFSVLLNYVTSRVVTEELKPLILPLHVVTLWRNWFGGQKSPTYVSKQERMRRAVAEVIDQQVLDRFQEPRITSRSPQDDTNLRLGAPVRTTERASAVDPEAKRDEADPARSSPVAPLKNDVVEIYDAIGMLLGRGSQSRWVPAQLSQSVKHAMFDLLAYNYNDSFSHAHKQAVMKLIGSQPLERGSRRYSALRRILEWERIVMKTITASATKTENRTVTSVVHLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEH9</accession>
    <name>A0A423SEH9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative chaoptin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003583">
        <property type="protein sequence ID" value="ROT62627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEH9"/>
    <dbReference type="STRING" id="6689.A0A423SEH9"/>
    <dbReference type="OrthoDB" id="10027416at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001164">
        <property type="entry name" value="GH01279p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45617">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45617:SF170">
        <property type="entry name" value="MIP14966P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019233457" evidence="3">
        <location>
            <begin position="24"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="774" mass="86674" checksum="4F311487B23B5CF5" modified="2019-05-08" version="1">MDWLYFTTLLAAWTAGGSSLTRAQEVSRTACPSWEDNPWCPCYHFDDGVFLECPMVSLNKVSRVLGLVQRAVKSLSIYDLDANVTKLPPGLFTSSAGVSSLQISHSGLQTISDGSFQGLENTLESLTIMHSQLTAVPQAALQTLTRLRALDLEANNITELQSFSFFKLKLVSLNLKGNGIKLISEYAFDGLHETLEELNLMNNKLKQLPIPALRRLSKLRTLKATWNRISDVINDGYSRLPALEVLDLSSNHFTQLTSSTLGTMPVLLSLSMYMNEISLLSGDAFVQNTRLQTLYLSHNDITNVEPETFTYTIYIRVIDLGDNHLHSISNGMFRNLPEIQEIFLNNNNILKIKNDTFTNSTKITVLYLQNNEIHSIESGAFANLELLFDLQLSSNNLVQIPVGLFSTTRSLSSLSLDNNRLTSLNKGTFAHLAELRELRLQNNRLTRIERLTMLERLNMDDNEIMDIEPQTFQKLPNLTTLDLSNNQIFVIRRYMFEGSIPLRTLNLKGSMINEIDPDAFADLRFLEELNLKKNMLVSLHKLYFRTPSIRNLNLADNHFDTVAEDSLYDLPNLDTLDLSGCRLENLPAHLLAEASELRTLNLARNNLPPGVFANLSITRLNLADNIFSQIPNAMFLDGMASLRTLNMSGNPMKRVTGILVAGGPPLAALEELEASRTNLTVLTSHDLLLTPSLRSLNLGQASIAKISPGCFRNLTQLTHLNLGFNHLEILPRERLRGLKSLSHLNLTGNSLKKLDQLPSDSHMLKASILWVLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHE7</accession>
    <name>A0A423SHE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative mRNA-decapping enzyme-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018517</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003415">
        <property type="protein sequence ID" value="ROT63595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHE7"/>
    <dbReference type="STRING" id="6689.A0A423SHE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09804">
        <property type="entry name" value="Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031953">
        <property type="entry name" value="mRNA_decap_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16741">
        <property type="entry name" value="mRNA_decap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="mRNA-decapping enzyme C-terminal" evidence="7">
        <location>
            <begin position="386"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="216"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="45141" checksum="396603D44ABA8EF7" modified="2019-05-08" version="1">MEQTRDTIRLNSVRRIDPHVSHIVDSANRTALYTYEQGGESWAKTEVEGTLMVYSRVAPPHHMVTIINRLNKSNFIEPLTSACDIQVKPPYLLFRSAKGVIYGIWFSETEDVQRIATAIQEHMKNDLPAAPQPAPNILDDPAIAVAGAPGGDILSMLSRAHGEYESKRNEPRSIVTTTTSVNNDLVKPAPLRVTAGEQNTVADFFAKVSGAQAGGGMGGLGTGLPSPSSSGPPVSSTANPSNAPLPVLQKLFQGAAAVGGQAMVQLPAGAPVQGQQGVTNPIPIPGSAPQPHPPAMSSSVPGGAPISLQELEGRFKDNLRMSNQVFTSSRTSDPVIHGTPPIETSCPRTFPGLLTPGTAAAMDMRPLNGSQESLHDGLLGGSSHVTPLTQEQLVQAFTLLLKKDDFVRQLHEAYVQALNLSLKGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIB3</accession>
    <name>A0A423SIB3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003350">
        <property type="protein sequence ID" value="ROT63941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIB3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="41028" checksum="AB320796041FBB74" modified="2019-05-08" version="1">MEGPVSGRVACGPAPPTIGRGAERRPWPAVWRRPRVSHGPFPRAAAWPERASGVGGRRAVPPSARQAPAPAGRMDGPVSGRVACGPAPPTIGRRRAPPLACCVAAAARLPLGPFPWVGSGFPHRPLAPSRAEGGGVGFGRGPAAPRRGVAPAAGRARGPWARSCVAEGLRRQRQGDCLGCGRRAASPASSSPGAGFGGAWLPGPSEGLPSLAPGPSGPCPRSCGLRARADNYRGTTFGSCGRAASSRRGRKPLPLRLPSPKAGQALGEAWLPGPSEGLPSLAPGPNGPCPAVVWAESARADNYRRAGLGWNAARRARVPSGPEPAEQAALGAGRRAWRAGQEAVQRGWRLGPVAPALHPRESEAFTGAWVVGRAEGVLSLGVAQEGALFAVVLAEGPRRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ89</accession>
    <name>A0A423SJ89_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative cyclin-L1 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003283">
        <property type="protein sequence ID" value="ROT64266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ89"/>
    <dbReference type="STRING" id="6689.A0A423SJ89"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="57"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="194" mass="21913" checksum="CD94003A861F34D7" modified="2019-05-08" version="1">MATATKEVMNPPLKKYGSVVLTLENVLLPPEKLSPSPSQLDGLDSEIEMDLRILGCELIQTGGILLKLPQVAMAAGQVLFQRFYYAKSMVRYPMETTAMACIALASKIEEAPRKIRDVINVFNHVRQVKNGKTIQPVILDSNYIALKNQVIKAERRLLKELGFCCHVKHPHKIIIMYLRLLEADNNRQLAQTSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJY5</accession>
    <name>A0A423SJY5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative bifunctional arginine demethylase and lysyl-hydroxylase PSR isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_017593</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the JMJD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003248">
        <property type="protein sequence ID" value="ROT64464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJY5"/>
    <dbReference type="STRING" id="6689.A0A423SJY5"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033749">
        <property type="term" value="F:histone H4R3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106140">
        <property type="term" value="F:P-TEFb complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006909">
        <property type="term" value="P:phagocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.270:FF:000001">
        <property type="entry name" value="Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.650:FF:000010">
        <property type="entry name" value="bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF32">
        <property type="entry name" value="BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="JmjC" evidence="13">
        <location>
            <begin position="142"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="336"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT64464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="44048" checksum="08A674969BF0C977" modified="2019-05-08" version="1">MDHRCRKRVREAKKKARPELCLEKGVWTKHDYKNKFDCSIDIVPDTVERIHANEVPTEEFIERFEKPYKPVVIEGVTDNWKARYKWTLERLYKKYRNQKFKCGEDNEGYSVKMKMKYYIEYMKTTDDDSPLYIFDSSFGEHVRRKKLLEDYDVPKYFRDDLFKYAGEDRRPPYRWFVMGPARSGTGIHIDPLGTSAWNTLLRGHKRWCMFPTDTPKELIKVTSAEGGKQVDEAITWFSIIYPRTKLPSWPEKFKPLELVQHPGETVFVPGGWWHVVINLDNTIAITQNFASCTNFPVVWHKTVRGRPKLSKKWLRILREKKPDLAAVADSIDMSKSCGMASDSSSDSSSSSSSSSDESSSSESVSDSGQESLPEHKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKA4</accession>
    <name>A0A423SKA4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenylate cyclase</fullName>
            <ecNumber evidence="4">4.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C7M84_017373</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003211">
        <property type="protein sequence ID" value="ROT64675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SKA4"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000001">
        <property type="entry name" value="Adenylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000002">
        <property type="entry name" value="Adenylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009398">
        <property type="entry name" value="Adcy_conserved_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627:SF26">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06327">
        <property type="entry name" value="Adcy_cons_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="19">
        <location>
            <begin position="27"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="19">
        <location>
            <begin position="507"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="776"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="876"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1000"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1208"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1455"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="793"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="889"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="916"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="930"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1000"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1026"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1040"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1209"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1262"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1300"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1321"/>
            <end position="1332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ROT64675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1508" mass="168277" checksum="944455A914E03460" modified="2019-05-08" version="1">MEMKADIIKPVERQFHKIYIQRHENVSMVFADIVGFTVLASQCTAQELVRLLNELFGRFDQLADDNHCLRIKILGDCYYCVSGLPEPRSDHARCAVEMGLDMIDAIASVVDATDVQLNMRVGIHTGRVLCGVLGLRKWQYDVWSNDVTIANMMESTGEPGRVQITQATLECLGNEYEVEPSDAQSRSQFLRDRNITSYFIIPPARRRKVRSALGSAHRRKLSFKNVSNVVVQLLHSIKYSMEVPFSNMAIPPQDKSTSITKKSTLSDKFKRPFKKRLSSLPHTPSNRVNKYLAQAIDARSVDREKSTHVSLITLCFRDREKERNFTCDLPHVPCKANVTDLTPLRSGPQEFVHNLWCPLPEYIPLSCIVGFMAVAVFLRLPVLVKTLLLVSMATVYSLLIFITHLPVFECYDIRVGALVPTEVLGVVYILLFLLAVIAHGRQVEWTARLDFLWQCQASEEKQDMDALQESNRRILFNLLPAHVATHFLDNQFRNNMDLYHQSYSRVGVLFASIPNFHEFYTELAVNNQGTECLRLLNEIIADFDELLDDERFKAIDKIKTVGSTFMAAVGLMPDMRILDKDDSANYYMTMLTELVFAFKDKLSSINENSYNSFTLRVGMNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGLPNHTQVTEEVYQVLRKGAYQFQCRGKVKVKGKGEMTTYFLVDRKEAPTIKAEDGPRPPKVPPHLQSYAPEHGCGWPVWAAYCVVGRCGGTLHPPHSSLRSHHRHYHTHNGGLYGGVATPLAMVPPQIPPHGRSLSQGLTGQGGQGQSGGTPRSRRNRDSFCDDNQVVNMNMSQCVSKMGGRQPSGECQRCEEEPLLDKVPPAPLSAHVLPPRFSVAQMRACNKSQTPTRAAMQQMKPQNQIPTTKTYSQSRPRTYRPDEYNLPQNSYVPTWARSQSGGRPSASGGKKSSGRSRTSPRKENDDGQMRPLDAGRTALSGGLVLPPMPRHHHVEEAGVRHKLRSFTRHYSDDSLHGSSHRDLQSTRIHSSADEISSLNRSPSLSSSDESFSRTDFSRTDADSPSPQHAPSLSDERFKYMFGGMNLEGAMAPGFRELSPQIYSDYLSSVKASSDESSLRLNSLSRDSTTYSYPNVPGLWRETDIASPTHDERMRRDDLVIPKLTAEFSSDKMKRSKHGDKADVEVPSHVDNCVSHSASPSSEKVRPGCRLSYVDCDINSPSRTSASGSTSRMRSLEKSPRESTAMTPDSVIMVPKKRSLSREEGMKIGNHVSTEHDIFRKRSTERPKRDGECQTDPRTHHHKNSATGVKTGDRNKPERKIEKSATFEGIPEDPKSTHRDGSEGRYGSSGRGRDSEREGGAQQHLSSDISNNNSSCNLVENYSGNTLEGYSALQKAARLQEDELNNVLASPEQFRLDSLTLEPLTAEPLSIDPVMLGLHFDPCVNQTVLQLTSASVDGVLKSQLPVKPQSAKRSLADPVPLDHRAKASRGPLGHRFPLEIPTPEKLAPHQGVRRNAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKR2</accession>
    <name>A0A423SKR2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017282</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003193">
        <property type="protein sequence ID" value="ROT64772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKR2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019498537" evidence="3">
        <location>
            <begin position="21"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="655"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="740" mass="79466" checksum="0A7FD5ED5E5F262D" modified="2019-05-08" version="1">MQANTASLFFILLQYQSVASSPLPRFPTPPYPLSPALLSLILCLSSLPLANGRIWFLTLAYIGNGKTASDLAPPSCISSPPLISSSSSSPSPSLHYHSSPLSSSSSFIIIHSPLVSFLLFIIIPLPFSSSSPSPPLHYHSPPLVSSSPFSSSSSLSFTLTLSPSSLLVSSSPSSSFSSSSLSFTLLHSFSLSFAPPPFPDHHSILLLLLMPFFSLSLFFFLFILFFVFFPFVFVFDTLFFLFFFFSFLLPSLLFSRFILLFLTRSQYLLSLLSFLLLFSNPCLLLLSLFYFLLVLSVPLFSFFSSIPFRFPNFNPSPPAPAPSLLFLFLLFFSLSLFSLFFFLSLSLLLSSSFSPSPLPPPSSLLPPLLPSPLLPPPPSPLPPPSPIFPLLVFLFLLLPPPSLSLPPPPPLLLLLLLSSSSFPSSSSSYLSPPTSILHPCTHPSSSSQLSTSATPPAPPSSFNLGSHSRPPSLPPPPPTFPHRRNHPHYPLLPLPPSLYHPPIPPLPSYPPTLPQPSTLQLFLSLTSSISSLPPSTPLSLLHTSSLPLLPILHLHPLPYLPLSPSLLHPFSLLLPSLLPYPHLLPSPHPPPPPIPPPFPPPAFLLPLSSSVPPPPSPPPRHPLLHPFPSSSLPPFPPPPSPHPPLPSSGPPFHPPTSSHPLSLPSLLCPPSPPPSPPIPSPSPSSSVPPPPSHLPHPLTLPTTSHPRTLPSPSTLPPPPTPSTLPPPPIALTPHPPSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNE0</accession>
    <name>A0A423SNE0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_016367</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003060">
        <property type="protein sequence ID" value="ROT65664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNE0"/>
    <dbReference type="STRING" id="6689.A0A423SNE0"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.210:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="11">
        <location>
            <begin position="129"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT65664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="605" mass="65690" checksum="8912F491E7F7EC45" modified="2019-05-08" version="1">MEFLLINHPLDCPICDQGGECDLQDQSMAFGSDRSRFLDNKRAVEDKNIGPLVKTVMTRCIHCTRCVRFASEIAGVEDLGTTGRGSDMQIGTYVEKMLMSELSGNVIDLCPVGALTSKPYAFTARPWEIRRTDSVDVLDAVGSNIVVNHRTGEVLRVLPMTNEEINEEWLSDKSRFAIDGLKRQRLIHPMVKDSAGELRPCEWEDALIVAGKALKAANGSVAAVAGGLADAESLIALKDMVNKLGGESVCTEEIFPDAGTGTDLRSSYLLNTKIVGVEEADLVLFVGTNPRFEAALFNARVRKAWVHNELDVAMIGPKVNLTYDYEHLGDDVNIVNSLLDGSHPFSERLAAAKKPMIVVGTNALSRGDGGALHAQLVKLSQKLRSGCEGEWRVLNVLQQVASQVAALDLGYTPGVADIRNNPPKVLFLLGADEGAITREDLPKDTIIIYQGHHGDHGATIADVVLPGAAYTEKTATYVNMEGRAQQTKAALVPPGMARVDWKIIRALSEIVGATLPYDTLNEVRHRMAEVSPNLVRYGDVEEANYFAQASALAELVKGNFDAAPLDVPLKKLEDYYMTNSITRASPTMAKCIAAVKKEASNKFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQM5</accession>
    <name>A0A423SQM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002928">
        <property type="protein sequence ID" value="ROT66479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQM5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="576" mass="65271" checksum="906B4FCCA8B9CE40" modified="2019-05-08" version="1">MSLFFSSFPLSLLSLPFSFPHFSLSISLFSSSFPPPHFFLSFLPLFFLLLPSSFPSTATKITDGNPTRKHPSPSQPHQSPSRTQRGIITLTLRQSSPSLYRKINKKQIRSVRTTEVTTTDQSPQDSHHRNHHHRPQTSHHPPDQTTVTTSHHHRPVTTEITTTDQSPQNHPPGPSPPDQSPQKSPPLTHQTDHITDQTQSPQTIITTTTTDQSPQKSPPQTSHRHRPSPQKITTTDQSPQNTTTDQSHHHRPVPSPQESSHQTSHTEITHRPVTTEIITTEIIITDHTTEITHHRPVTTNHHHRPVTTEITTTDHTTEITDHHHTEQTTSPQKSPPDRSPHIITDQSPTEITTHRPVTTEITTTDQSPQKSPPQTSHHRNHHHDQPPSPPITHRPHHRITTTDHHRNHHHSQSPPEITRPTTEITTTDHHHRPVTTEITTTDQSPQKSPPQTSHHRNHPTTDQSPQKSPPQTSHHRNHHHRPVTAITQSSHRPVTTEITTQTRPVTTDQSPHTTHQSPPQIRHHRPVTTEITTTDQSPPQTRHHRNHHQCLTTIPLPPPLSLSPSLTAEIRHFQVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQZ5</accession>
    <name>A0A423SQZ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Muscle M-line assembly protein unc-89</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_015340</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002916">
        <property type="protein sequence ID" value="ROT66618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQZ5"/>
    <dbReference type="STRING" id="6689.A0A423SQZ5"/>
    <dbReference type="OrthoDB" id="6371610at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043065">
        <property type="term" value="P:positive regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342:SF14">
        <property type="entry name" value="DEATH-ASSOCIATED PROTEIN KINASE DAPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24342">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ig-like" evidence="9">
        <location>
            <begin position="85"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="10">
        <location>
            <begin position="180"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="328"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT66618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="639" mass="73122" checksum="F04728BAD1D939A0" modified="2019-05-08" version="1">MNLDKWLRIPIVHERRRFTDVMDEEIDDERKRTALDRYTAGFVRSRMETCSLDMPRRVKQEVPSRLSIYDEVVVMKEGAHYGTAPFLREKPGTCAITDGCPLTLTCVFTGDPEPVVQWFKNDIILGENSRVSIHTANGRSTLAYQECHDYDVGLYKVVARNTLGQATHRFRLVQGHIPGPCDSPDVSEKSDTEVLLHWSPPADDGGSQILCYHVQMKLPGDTEWLTVSDNIDHEFFLVKGLTENSIYQFRVAAKNFVGWGDFSRVKSRVIAGAPKVRTTREMQILQQATESGKIVLPFLEKKELDYRKETDPVKLKSGENAQLQVRKYDMIAELSRGRFSVTARCIRSDDRRHFAAKLLENYDREDVVREEFEVFKTLRHERIAQLYEAYNVGDVTVFIMEQLAGLDVLTYLASKREYSEQHVVTIAMQVLDALSYLHWRGMCHLDVQPDNVVLTTPRRCDVKLVDFGSTQRVSKQGSTVPVSGLLDFVAPEVLAEQKAFPSSDIWSLGSLIYLLLSGKSAFGGVDDEDTHQNILHVRYRYEHLGSNTTQEAIRFLMLIFKRDPSKRPTVDDCREHKWLVENDYIVKKRERATFLGSQLRDFDQAYHKERAIAATKSLHLLTYGGKEIPAAITYEPETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SS39</accession>
    <name>A0A423SS39_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Methionine aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_014954</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase M24A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01002870">
        <property type="protein sequence ID" value="ROT66986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SS39"/>
    <dbReference type="STRING" id="6689.A0A423SS39"/>
    <dbReference type="OrthoDB" id="7848262at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000106">
        <property type="entry name" value="Methionine aminopeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 14" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="13">
        <location>
            <begin position="155"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="13"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT66986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="52003" checksum="5FA96B6C08A977AC" modified="2019-05-08" version="1" fragment="single">WRCRVSKCSRWSGGLGREARSHNLKDGKPEAEEGGSSATKKKNKKKKKASGEGGSEEGENKAGLVNGTADLADKMKKTEKVSCLSIEYPISCSSWMPIQTDPPTVPIVDLYPDGNLPIGEICEYKINKDDRSAINRMNSDEKKALETSFEEMYREIRIGAEVHRTTRKYFKENVKPGMSMIEICHMIEETNRKLIKENGLKAGLAFPTGCSINHCAAHYTPNSGDKTVLNYDDVCKIDYGIHINGRVIDCAFTLTFNDRYNNLVEAVRAATNTGIREAGIDARLCDIGAAIQETMESYEIELNGKTYPIKCIRNLNGHSIAPYRIHAGKTVPIVKGGEAEIMEENEVYAIETFGSTGRGYVHDDMETSHYMKNYDAGHVPLRLAKSKHLLNVINQNFGTLAFCRRWLDRLGESKYLMALKDLCEKGIIDPYPPLCDVKGCYTAQFEHTIVLRPTCKEVVTRGDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUP3</accession>
    <name>A0A423SUP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013933</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002736">
        <property type="protein sequence ID" value="ROT67952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUP3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF14">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="434"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="600"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="690"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="718"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="832" mass="94814" checksum="5D4428394A62CB36" modified="2019-05-08" version="1">MTFNHSFRCVIRKTNLLRSYRCASPICGCIQAYAFFSSFSLSSFLFSSFSLSCLPISLFFLRVYPSFSCLSIVSIHFCVYPSFVSIHHVYHLSFSPRVYPSFSFPLVSIHLSFFPSCLSIFLFRSIHRVYPSFFFRVYPSSCLSIFFFPSCLSIFLFPRVVSIHLSFSPRVYLVSIHLSFSPRGVYPSCVYPSFFFPLVSIHLSFSLVSIHLSFFPLVSIHLSFPLSIIFLPRVYPSFFSLVSIHLFFSCLSIFLFLVSIHLSVFPSCLSIFLPSCLSIFLFSPRVYPSFFFPLVSIHLSVFPSCLSIFLFFVSIHLSFFPSCLSIFLFSPRVYPSFFFPLVSIHLPFFPSCLSIFLFSLVSIHLSFPLVSIHLSLFPLVSIHLSVFPSCLSIFFFSLVSIHLSFFPRVYPSFSFFPILCLSISLFFLRVYPSFFFPLVSSSCLSIFLFSPSCLSIFLFSPRVYPSFFFPLVSIHLSVFPSCLSIFLFSPRVYPSFFFPLVSIHLSFFPLVSIHLSFSLVSIHLSVFPRVYPSFCFPLVSIHLSFSRVYPSSFFPSCLSIFLFPLVSIHPFFFPSCLSIFLFSPSCLSIFLFSPRVYPSFFFPSCLSIFLFFPLVSIHPFFFPLVSIHLSFSPRVYPSIIFLFFPSCLSIFLFSPRVYPSSLFFPSCLIHLSFFPLVSIHLSVFPSCLSIFLFPLVSIHLSFSPCLSIFLFPPSIHLFFPLVSIHLSCLSIFLFFPSCLSFHILRHTCVTVHPSGRRSKRLVSQVTSFQEPFLGGLKRRICPCGSATAPQTASSFDLSRRGSARIRLRDPVEGGERWASRGGDGPLPSVTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVE1</accession>
    <name>A0A423SVE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002711">
        <property type="protein sequence ID" value="ROT68171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVE1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="38922" checksum="D61AA76F24B147C2" modified="2019-05-08" version="1">MHGGTLNADEREEEKGKKKAKVGESAAFPFTCPSSPASLTSPSSAPPPQPPSLPFPCLSSLLLPFPYPSPAFFPSLSSVFLPSPPSPLSSPPSPPFLPSLPTSLSAVLPSPPSLFPPPPPSGPEADFAELLSYACLVLQVRLGVELWEVGEPLGRAAGDPGGEGVGGALSPPGDSQGGPGGPGTTRSDSSRSDTSSSGASSSCCSSSGGPRRPCLHAALSDPGYESAHLPDDDRDDPEHSRRQQLCHSGGGMSLRERCEGRDGSPLHQGLTRSRSFGGLLSHRRPCHRPGTCAASCRSRRTSRCPSRRGRNARRRSARAWPPAFGSACPSPGRTSTPSGRHSRIRSCSRCLIKASTSPHPHSPRNDIVEMRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXG7</accession>
    <name>A0A423SXG7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Trypsinogen 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_012949</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002624">
        <property type="protein sequence ID" value="ROT68887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXG7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000077">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF83">
        <property type="entry name" value="COMPLEMENT FACTOR I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT68887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="24392" checksum="0E51F7D52F66279F" modified="2019-05-08" version="1">MADNHYVWHLKLPGISFGFAWHFCGASIYNENWAICAGHCVQGEDMNNPDYLQAKLNQDVDEGTEQTVILSKIIQHEDYNGFTISNDISLLKLSQPLSFNDNVRAIDIPAQGHAASGDCIVSGWGTTSEGGSTPSVLQKVTVPIVSDDECRDAYGQSDIEDSMICAGVPEGGKDSCQGDSGGPLACSDTGSTYLAGIVSWGYGCARPGYPGVYAEVSYHVDWIKANAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXY5</accession>
    <name>A0A423SXY5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002610">
        <property type="protein sequence ID" value="ROT69051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXY5"/>
    <dbReference type="OrthoDB" id="6364835at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="170" mass="17626" checksum="DFC84345C2BB4A47" modified="2019-05-08" version="1">MKRAAKEKAMSEQTTSSNQSASPRRISVPVLVKEENATKGSSSTSSSAAGGEGKLGHHRDTSSSTSSSSLAASNTSSLLPSHLTCDPASALDPFRSQGSATPVSASAFPSMTPLHHNANNAYLHHQRAILTPVARNGASLRGRGGPRTSPGEHANRARRPTGFSVEDACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZ57</accession>
    <name>A0A423SZ57_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012291</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002557">
        <property type="protein sequence ID" value="ROT69524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZ57"/>
    <dbReference type="STRING" id="6689.A0A423SZ57"/>
    <dbReference type="OrthoDB" id="2018023at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14316">
        <property type="entry name" value="UBA2_UBAP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1920">
        <property type="entry name" value="UBAP1 SOUBA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038870">
        <property type="entry name" value="UBAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042575">
        <property type="entry name" value="UBAP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023340">
        <property type="entry name" value="UMA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15960">
        <property type="entry name" value="LD44032P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15960:SF5">
        <property type="entry name" value="LD44032P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51497">
        <property type="entry name" value="UMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UMA" evidence="3">
        <location>
            <begin position="9"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="485"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="552"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="593" mass="64683" checksum="74E489C6813AC36C" modified="2019-05-08" version="1">MSTDPAAFVAGVPVKISERFRPPRRVTIPASCQYQINPDLLTQDYDFAIEKTTLKWVQERLQPGLVKSGMGTNFYRNDAVYNANPSYESDTSMAYPGMLQPTPIPSQKNNLRSPLKTPADINFAEFEGEGNDPFDSAALKSINDMEELAKVLDSTNMGTGSQSLDRNTVSKQNSSEDKRTIPTTYPNGQVAYNAYGQYPYYLQQQLHHTVPQPGQNFGQFTGHLGKNSPVTSAASPVPSYNNSHQYGGGPDRSFQNTYYPQQWNNSYSAGSPNKGAPFGPYDYRLQANNSVPSTSQGVLSPSNITGTVTAAPTVPVSMSSGLSNSSTIERGTVGKRQDLEDFYTRYYSPNKSTVTQAQQSGVRSGDSTPSHSSSSGALGSTTGSLRSCRSVPDLSAAEDSEVTSYNSRIPSAGEGRGFSHTPPPRPSSTGLSGLEDWKPLPDLPSTPESSPAQHSYQQGLSQTTVGSHQYTPTKTRLPDPFIELTADAQALVQSMAEMGFPRPRVARAVQKLGTDHKKLIEVLLVLQNLQDAGEDEYKAERAFYHYMGDLQKTKDHLAAAKQLCDLGFEDERIVDALLKHDNDRDKALEELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0G6</accession>
    <name>A0A423T0G6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Neurogenic mastermind-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011736</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mastermind family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002485">
        <property type="protein sequence ID" value="ROT69990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0G6"/>
    <dbReference type="STRING" id="6689.A0A423T0G6"/>
    <dbReference type="OrthoDB" id="5982619at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046370">
        <property type="entry name" value="MAML_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019082">
        <property type="entry name" value="Mastermind-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09596">
        <property type="entry name" value="MamL-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01275">
        <property type="entry name" value="MamL-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neurogenic mastermind-like N-terminal" evidence="5">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT69990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="334" mass="35683" checksum="3DFA71D1D0A3D4FB" modified="2019-05-08" version="1">MVEPSIPSHMEMAPHAYTSPVLVAPREPPRFPDAKEDCVGTRCGGEREAPVLPMHRVVKSKCITANHVILLWPPRVGGGTALAGGAAGPDNMADLQDRQVVFDRLKRRLSNYRHNHNSVTQRYDTSIDLVYSSEQKQTSILKQRHIESKAKKSNKKTTDNKKQDNSSLLATMGQSKMLARGHDQTTSSGESHENEPAAKKQRLNNGAPPHGGPHGATHAATSHGGPPHVGGPQASGAAGDINNFQMVQQLPNMKKTNSPVPAGAGPAGATTSASNGPPVEDVKKEQQDLDIALLDDIEDFSNIDPQADGRAAPDQNGVVRTEQCAAEFPGIPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2Q7</accession>
    <name>A0A423T2Q7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calphotin-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002398">
        <property type="protein sequence ID" value="ROT70693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2Q7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019161993" description="Calphotin-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="41718" checksum="716E271CDD99C5B7" modified="2019-05-08" version="1">MPLPLQVLAVLAASCSAAPQMFRAVSGDLFLLRSDIPAVVKIPEPGIKLAAPLTEAVALVSIPASPVAPVVKTVEVVASLGTVVESGAVVAPAAPVVVEPVVKNAEVVAVPTPVVKSAEVVAVSAPVEVDPVVKSASDVAPDVGVIVEPVVKSAVVAVSAPVVVDPVVKTPVAVAPVPVVKAAPVPVPCPPLKAAPVPVPVVKAKAAPVPKAAPVPVPVVKAAPVPVRSLRLPLWLWPLLPRWSRVQPLWLLLPLWQSPLWSRALSPSLWWQRLSPSWPLNPPCPPSASLTWEANSTPRTRPASTPSATTAAQHPRGDQGLFGSYLRQLRLRGPRGGRPGEEVRRRPGSGFRVAASDLVEDTPAVAQVKSAHARAHETAKSLVRDAVCTRHAHAHEMSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T420</accession>
    <name>A0A423T420_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Eukaryotic initiation factor 4A</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP-dependent RNA helicase eIF4A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_010513</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002333">
        <property type="protein sequence ID" value="ROT71181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T420"/>
    <dbReference type="STRING" id="6689.A0A423T420"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 18" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="58"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="239"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT71181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="45451" checksum="54913BA11F9DDEC6" modified="2019-05-08" version="1">MKSGELVEAVVVGTMIIRIMMAQPVATSFDDMNLNESLLRGIYAYGFEKPSAIQQRAIMPCIKGHDAIAQAQSGTGKTATFSIAILQRIDSKSQETQALILAPTRELAQQIQKVVLALGDYMNVSCHACIGGTNLREDMRRLEMGVQIIVGTPGRVYDMINRRVLEPKDIKMFVLDEADEMLSRGFKDQIYDVFRFLPHDVQVVLLSATMPADVMDVTTKFMRKPITILVKKEELTLEGIKQFYVNVEKEDWKLETLCDLYETLTITQAVIFCNTRRKVDWLTDKMHQRDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTADDARILQDIEEHYRTSIEEMPMNVADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T477</accession>
    <name>A0A423T477_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipase maturation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010493</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the maturation of specific proteins in the endoplasmic reticulum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the lipase maturation factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002331">
        <property type="protein sequence ID" value="ROT71203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T477"/>
    <dbReference type="STRING" id="6689.A0A423T477"/>
    <dbReference type="OrthoDB" id="434126at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009613">
        <property type="entry name" value="LMF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057433">
        <property type="entry name" value="LMF1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057434">
        <property type="entry name" value="LMF1/2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463">
        <property type="entry name" value="LIPASE MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463:SF5">
        <property type="entry name" value="LIPASE MATURATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06762">
        <property type="entry name" value="LMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25179">
        <property type="entry name" value="LMF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 N-terminal" evidence="9">
        <location>
            <begin position="103"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 C-terminal" evidence="10">
        <location>
            <begin position="416"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT71203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="637" mass="73028" checksum="80E75FCA5E2DA20A" modified="2019-05-08" version="1">MFAFGSLYLQIPGLYGEKGVLPAHTQLPNLKYPKQCFMDKLTFLCFSSYFGLNVSYMMEFISLAGTVLSFIGMVWKSWCTATLFLLLWSSYLSLYQVGQTFLWFQWDILLLEVGFLTILVAPVSRRGWFEYRPRNLVTMWLIRWVLFRLMFASGVVKLQSGCPTWWGLTALNVHYESQCIPTTLAWYFHQLPGWWHKLCVVATFVIEIPVPFMFFSPVRSHRIFSCYAQMLLQIMIILTGNYNFFNLVTLTLCLSLMDDVHLGYQFVKDLSFGFISYVKNTCSWFGKWVGFGILIYYTMAYFSLRVTPEGTIESVVAFTREEFDAWMSRAVPLSIAIGAFSLVITIAEALTSALFEVRGFLDKFGVFSTTFIYSVAAICMFGISLVPYTVLDRPTSQRVWPVFQHLYGHTSDFHLTSAYGLFRRMTGVEGRPEVILEGSNSLDGPWIEYEFPYKPGHVERPPPVVAPHQPRIDWQLWFAALGTYNQNPWLISLAHRLLSGQPEVIALLDISSPWRDNTPKYIRASKYTYQYTSIKEGASGSWWKRTYEGDYLPIFTVDHAPLVEYLRKIGTIGTMDIPATNQPLQHGLDAIRGWINIASPEVLLWSLFITACVITWTKRGVKPSMSYRSAKHAGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6I1</accession>
    <name>A0A423T6I1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009551</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002209">
        <property type="protein sequence ID" value="ROT72092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6I1"/>
    <dbReference type="STRING" id="6689.A0A423T6I1"/>
    <dbReference type="OrthoDB" id="10039134at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061564">
        <property type="term" value="P:axon development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007423">
        <property type="term" value="P:sensory organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19712">
        <property type="entry name" value="bHLH_TS_dimmed_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF167">
        <property type="entry name" value="PROTEIN DIMMED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="62"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="248" mass="28482" checksum="3E62675ACD172A34" modified="2019-05-08" version="1">MGAVLTYDGRRCRRRRGHSPHVVTFFSATCRKRKKTNLSGSTGPSRRGKKRRSGISARERNLRRLESNERERMRMHSLNKAFQELREVIPHVKMDRRLSKIETLTLAKHYIMALTNTVCDMRGDEKPYNKAPRFRWKPKPAASHGSRSRSNGLRFLSHYEENWKYCGVGAWQSPSHTMVIFHSGPSIPCYNVLLNVIKYVDVTLVPRPQSENVLSSGSNHICKGLAHLIVAPSGTLWEYDLTQLNLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8P7</accession>
    <name>A0A423T8P7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002102">
        <property type="protein sequence ID" value="ROT72840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8P7"/>
    <dbReference type="STRING" id="6689.A0A423T8P7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="41289" checksum="070B74880944FA50" modified="2019-05-08" version="1">MARTVSVRFIHLARHTPPLPIPLPPPWVKGGDVGEIQRRRRREPTQDLQGRVAPLGRGGSGALWGSLGLPAVLFGFPAAPSRLPATAYGYLSLPASPCDFLSLLANSCFSLDLLWLPTTPCDSLRFPESPCSSLLLPWLPTAPYFSPCDSLQLPAPPMALCFSLLLPPPCTSLLPWLPMSPYFSPATPSFSLHLPRLPKTPYFLLATPSFSLHLPKLPKTPYFSLLAAPSLLPASPYTSHGSQRLPTSLPATLYNSLHLPWFPKTPSSSLSPLHLPAPLLLPSSMALCFSLLLPPPCTSLHLPWLPTAPYFSPCDSQRLPSSPYTSQSSQRLPSSPYTSQGSLRLPPPPPSSPCTCLPPPPSYLRTPTYKPINLWWKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB40</accession>
    <name>A0A423TB40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">JHE-like carboxylesterase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002008">
        <property type="protein sequence ID" value="ROT73666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB40"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="234"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="45605" checksum="742BFA940BAA348A" modified="2019-05-08" version="1">MWGRGLFQRAIMQSGAALCPWALREDHRQVAFGFGRMVGCPGERADAANSTALVDCLRDVPVEQLMAVTPYITVSERPSGRLIESLPYVLTPRVDGEFLPAHPATLVREGRYNRVDVLSGVTRDEAPSTPEHFATWRSNFEVKGNLFLASSSAFVEDGVMDSMIQNFSLVAPRPRLRGLGRRPRVPGPPGLPQVPGAHGVRPDQDRPSRQGKTSRASPDATGLSEKCSLERLRLSLLGDSFYSMCHVEAVEHHARDAAFGFRAFAYELQHRGEHAFSDLFRGPSPVEPGLSGGDRHKGFSRTDVGDSDDLQYLFSFDKLNVSLTKEEDLFVSRIMVDLWTNFAATGNPTPDLSLGFKWTPTEASSLSYLGITSAPAMKVYDREQDIEFWRNLPRKMNKLLYPDRFSQNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBS9</accession>
    <name>A0A423TBS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001978">
        <property type="protein sequence ID" value="ROT73857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBS9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="540" mass="59096" checksum="242B71D5C10457AD" modified="2019-05-08" version="1">MTLLLLFSFPFPPFFPLSLSFPSSSFSSLPPSSAPLSLTLTLFFCFFLPFLLLSLTSPYSPFLKFRSFCSLLHPPFFPLLFPLSLHAFPPPFFSTLLPSPLYFHLPPFLTSFLSTPFHCPNFLLSTHPFSLPFSPSPHFSYTPFLFLPLSLLPSLLPLSIYSAPLTTFLIILPPSHHPFPPLPLFPSLPPLFPFLLSLQSPPFPFLSLPFPLPLSLLLSPSVFLSISSHPLPLLSLYFPHSSSPPISLHSLTILSILPLPFPSPLPSHPFSLTTTLSLHSPPSFNHPSLPSLPSHLSIFPPIPLSPFPPHHLSLSPFPPISPFPFPLHPPSLLSLPIPLSFPLLSPSPSLSFHSHLPLSHSLPISISPFPSPSPSPPLFPPHLPSLLSLPIPLSLFPPHLPSLFPTFLPIPSLPPFPSPSPSLPLPFFPTFPSPSLSSLPIPLSSLFIPHPPFPSPPPSLFSLPIPLSPFPPYPPLPPFPSPSPLSLPPHLPFPLHPPSPNPPPLFLSPLFPSPSLPSLPLTLYSPSRHNYRLGRGCQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TC19</accession>
    <name>A0A423TC19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">SET and MYND domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_007477</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001949">
        <property type="protein sequence ID" value="ROT74043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TC19"/>
    <dbReference type="STRING" id="6689.A0A423TC19"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042826">
        <property type="term" value="F:histone deacetylase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052097">
        <property type="entry name" value="SET-MYND_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46165">
        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46165:SF7">
        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="9">
        <location>
            <begin position="297"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT74043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="47265" checksum="8FA82D10803E2181" modified="2019-05-08" version="1">MADAYEQLLRKIQAGLQQKMAGEQAAGEQEESLLIRATGVLDAIMEEFQEQRTDLERVQYVSQMSEIQTFSLKENYAQKSAEDATNYEKVYDMLVPNEASANKALDVIKKCLLKTPPEDTLALATRYMKRGWTYLLLEQFDNAKVDAMKSLSFKCPDEQMWNAYEILGHCYAMSKEYKEAEAQFLKALEYLRKSNISNEVKAATTVRIMSVFKTVKGKKQKKASSAAAEKPATRHVPQLSYGVNKRFPSASSAVNFVRSPMVGRCALAQRDIKPGDILIIDEPYVTMMNADVCGSHCYNCFSYCPCPIPCSSCAKVSYCSDSCYAASWEKQHKMECKVLNHLMDPEIGKVALLVFRALVMVSWSKLQKLKEKLLTVIDEEKCEAPNLVAEEVSTDYGNTDTPLSSTKVSTAILLFYIYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF56</accession>
    <name>A0A423TF56_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative titin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
            <location evidence="1">Sarcomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001808">
        <property type="protein sequence ID" value="ROT75124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF56"/>
    <dbReference type="STRING" id="6689.A0A423TF56"/>
    <dbReference type="OrthoDB" id="6070751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030017">
        <property type="term" value="C:sarcomere"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000345">
        <property type="entry name" value="Muscle M-line assembly protein unc-89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000425">
        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF4">
        <property type="entry name" value="MYOPALLADIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="105"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="205"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="321"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT75124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="360" mass="40476" checksum="8C1B7F367115658B" modified="2019-05-08" version="1" fragment="single">MHHAQTYTSKLRCVWNKHSPPATTEILIRPLSTPRVGVADDRGPIQLERTKASTSWRCRNPGGRVTSFHPESPPTTDCSVLEAQDKINRNLVALSQMESVPTMAPQFTMRLRDRRVQVGFPVRLTCQIVGIPKPVITWYKEGILMSPDDCHTMWQEDGHFYTLEISNSTHDDAAVYSVRASNPYGSVMCRCRLVVDSGLTSYISPMFLRELEDQSVREGSTITLQTVIEAYPTIGVVWHRDGQRIRPTRKHSFNLDADGIATLTIRGADYTDGGIYTCTASNEMGHIESMCRVSVSCTDSDLAAKKRLTSKLTHPWLSKEPMFVRKPRAIEAEEGDLVIIECEVAGDPKPDVTWLKDWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF76</accession>
    <name>A0A423TF76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006447</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001817">
        <property type="protein sequence ID" value="ROT75027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF76"/>
    <dbReference type="OrthoDB" id="6362958at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008253">
        <property type="entry name" value="Marvel"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51225">
        <property type="entry name" value="MARVEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="MARVEL" evidence="7">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT75027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="18040" checksum="F4FA2D0555BEDC30" modified="2019-05-08" version="1">MDGYRRSQFIISPPAILKAGEMLILVTGMILFLVENSCPGDGAFLAMYLLPCGVCLAATLVSYVTAVLVLVGGRNPLTTPAWVKGDVWFNVCALVLMLVGSVLTLTRNECANNYSMVIAAIALGFISVILYASSGAVTYVILTRHREEVKAAQRAQLEDRRVTLSALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGL9</accession>
    <name>A0A423TGL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001750">
        <property type="protein sequence ID" value="ROT75623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGL9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="43052" checksum="0D7432D26CA1756C" modified="2019-05-08" version="1">MPNTWNGELYLFFLLPLNLYIHFHFWLDCSSYRHSIHSSPRFQLSFFPPICVHLANSSPPPLAPLFHFFFSISPFLHFRLHALRASFFIHSQVYEASTIMRGNESSRTLPLLSLPCPSPYSLTPSFAVSFPLPLPYLPLLSNSLFRHPLPPAPPLPLTLLSSPSFAIPFPLPTYPPLPLPLLSNPLFRLSPFPYPLYPAPPPSPQFHFSSYLTCPLILPFIPFPFLPYPILSSLPPPPSVLLSPLPPSPTTIPPTPFPTHTPLLPPISSTLPTQSPSSPPLYLLPPPPTLSLPPLLPPPTHPFPIPPLPPPLSPSPLPTNLLTHHHTLLPPSLYPLSLCPLPLLFVPSPYTLTSTLPPLPSPPPLHLLPLLPPSTLPLSLLLPPLYPPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH75</accession>
    <name>A0A423TH75_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heme-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001732">
        <property type="protein sequence ID" value="ROT75806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH75"/>
    <dbReference type="OrthoDB" id="6424451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.80.10:FF:000002">
        <property type="entry name" value="Heme-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF1">
        <property type="entry name" value="HEME-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="491" mass="55255" checksum="2DBD9E56A4B32FB3" modified="2019-05-08" version="1">MKPKGYQVKDTHFRNEILLKRTTKGISQSSFIPQRADITPRISRMRCFLVLTLFVAAASALPPSWVRSFLSRKQEEAKPSNGYEERTYPARKWGLLHGDTGDAEDEDDRDRAMFKRLYRYIRGNNDMQERLAMGAPVTTQVTMGEFSNAYEMCFYIGEDHQASPPAPNDQLVTIQDRPQITVFTRTVGGYMHDDEDWLTEAARLAQVVEAGGEAVSHDDMYWVGYDPPFKFWHRRNEVNDSVSGYLGAHVGLAIGSWRAGWRGKKVLGGGQTAAEEQETKMAGMRMATLVLATGMLATLFQPSLAGSLIGAFSNSLGPDEIIKYDVVQEGNGFEERKIPSLNWACVEQESGSSEADQMEVFFRLFGYLGGNNIQGVRMNMAAPVSIEYVKNGTDVVLSGCFLVERRHQQQPPEPTDSSIKIKERPEMNVLTRKFGGYATSDSVWLRETAALKAILTAAGKEVRSDLMYWNAYDAPFKFWNRRNEVWLLEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH92</accession>
    <name>A0A423TH92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Copper/zinc superoxide dismutase isoform 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001726">
        <property type="protein sequence ID" value="ROT75826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH92"/>
    <dbReference type="SMR" id="A0A423TH92"/>
    <dbReference type="STRING" id="6689.A0A423TH92"/>
    <dbReference type="OrthoDB" id="2015551at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006801">
        <property type="term" value="P:superoxide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="entry name" value="Superoxide dismutase, copper/zinc binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="SUPEROXIDE DISMUTASE CU-ZN -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="Cu,Zn superoxide dismutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019153097" evidence="2">
        <location>
            <begin position="23"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="3">
        <location>
            <begin position="122"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="645" mass="70159" checksum="69704D1EA351BD2F" modified="2019-05-08" version="1">MTTLLLLVCVCSVAAGLQKGSAKPCSEPEGFGGTVVATLSEDRALVVDDGIHKQLLLCISGKWSSAKLELPAFPAFDARGRLPKGPPVSGGRAKRSPNTGKYSDLRRRVKVQRKLQRGLLETTIEENTLSSVRVHPGGTAYLLCRVQNLGTHSVTWTRLKDSNVLAIDTLLISSDQRLSPSFEEQTGTWILRIGEVRPYDAGQYECQVSTRPPLKKVVTLEVVPAGQALDPPAAQEENGLDYVLQNLTAVWEELAYLRSEVDGHFHAGHEGRYHHQVVDEVAIMNHERHVHHLHHPHTSHNAHHNNDLLHHLKHHGLDQRKRPSHSHQGKHDQDDQDNGGEESGEDNGAETDQVYHEDDHDTHGLHALRDYDLDAFNLRDLAFDQGHGQGSGHGHAHVFDVSHNHDHGHGTSHSRLHSHESSHSHDGSDEADNSQEAGRQPSRSPVQAAPGRGLALIPGREPISTVPVNPADPWMYAKCDLKPNVDVPESAVRGNITISQLKSGKGPVYFDLHITGFDVASTGRLHGFHVHELEVKDGSCGSTGGHFNPHAQTHGAQDASVRHVGDLGNIEVDEDGNVEGHILSDRLVAFSEPNKIIGRSIVVHAGEDDLGLGGDSGSLATGNAGGRLACCTVNIMAMPYFRFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THI7</accession>
    <name>A0A423THI7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005546</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001716">
        <property type="protein sequence ID" value="ROT75901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THI7"/>
    <dbReference type="OrthoDB" id="6370264at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019216960" evidence="2">
        <location>
            <begin position="19"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="291" mass="31414" checksum="5BC2B29872E92365" modified="2019-05-08" version="1">MNVFALVFLIFAVLQTCAEQLKTKVLPELSSHTFRENTDMSFVFFATSRLRINLTLNKEPYVLCREIPGAKVVLRKLGDGFGQCLDGVTPYEYHEIKLTLQSNNFFRIEDPSAAAISPDVLGPVTVDILVGKVVDESLDNVTDKGGAAYVAPDPPGDPAVTSGGNDPGSAAISPRIGQKEAQATPPPPPRPTNAQTPCQTRTPLAKANVVRPVDRAILDQELAGANPKWKPPAGGFRKKSDPQAVVGFRKISDAPAPQPCEDDDYLSLGSGYPPPQQYGRGFDSRGYPAYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THQ6</accession>
    <name>A0A423THQ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001702">
        <property type="protein sequence ID" value="ROT75992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THQ6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="31539" checksum="66E640A99AA24134" modified="2019-05-08" version="1">MSHFRELGTPEARSESQKPWNVMGVKSVIFTSLHTESTLLIHHRLNNHRIILRLSSESAANRPETQRESRTHTTLEGPPHGESRKQSSSPSSFLSRFFPNWRDSRLGKPRPRESLSVGPLFLPCRGNNNPKKAGEKGENPSASFKFKVTRDLLLLLPHRWQKRRVLVPTGLLIPPGSRGGRRERGETREAEGKIFSKGRKPEGKVFSLPFVQVKPPPPTPRLTNRFLARSSTASCTPYQHTTIEEGTTRAIGQTSDARLAHDGTLRSLLFALISFIFLSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJG5</accession>
    <name>A0A423TJG5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative alpha-actinin, sarcomeric isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_004825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001637">
        <property type="protein sequence ID" value="ROT76585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJG5"/>
    <dbReference type="SMR" id="A0A423TJG5"/>
    <dbReference type="STRING" id="6689.A0A423TJG5"/>
    <dbReference type="OrthoDB" id="18853at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21216">
        <property type="entry name" value="CH_ACTN_rpt2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000001">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000004">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000005">
        <property type="entry name" value="Actinin alpha 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019299415" evidence="4">
        <location>
            <begin position="21"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="23"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="5">
        <location>
            <begin position="536"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="144"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="657"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT76585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1081" mass="125064" checksum="6C1FE99E29ACF985" modified="2019-05-08" version="1">MTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHTSFKDGLAFCALIHRHRPDLLDYSQLSKDDPLHNLNLAFDIAEKHLDIPRMLDPDDLVNTPKADERAIMTYVSCYYHAFQGAQQAEMAANRICKVLKVNQENERLMEEYERLTSDLLEWIRRTLPWLQARQQDNTLADLQKKLEEYRLYRRNHKPPRVEQKARLETNFNTLQTKLRLSNRPAYLPSEGKSVTDIANAWKNLEGCEKSFEEWLLSEMMRLERLEHLAKKFKHKAEIHESWTAGKEEMLQSQDFRHCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYYDSATINSRCQAICDQWDRLGTLTTSRRNALEETEKLLEKIDQLHLEFAKRAAPFNNWLDGACEDLVDMFIVHTIEEIQGLIDAHNQFKATLGEADKEYQAIMSLVTEVQHIAQQYQIPGGLDNPYTTLTSQVISSKWGEVKKLVPARDNTLQAELQKQQKIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHTSFKDGLAFCALIHRHRPDLLDYSQLSKDDPLHNLNLAFDIAEKHLDIPRMLDPDDLVNTPKADERAIMTYVSCYYHAFQGAQQAEMAANRICKVLKVNQENERLMEEYERLTSDLLEWIRRTLPWLQARQQDNTLADLQKKLEEYRLYRRNHKPPRVEQKARLETNFNTLQTKLRLSNRPAYLPSEGKSVTDIANAWKNLEGCEKSFEEWLLSEMMRLERLEHLAKKFKHKAEIHESWTAGKEEMLQSQDFRHCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNALDYYDSATINSRCQAICDQWDRLGTLTTSRRNALEETEKLLEKIDQLHLEFAKRAAPFNNWLDGACEDLVDMFIVHTIEEIQGLIDAHNQFKATLGEADKEYQAIMSLVTEVQHIAQQYQIPGGLDNPYTTLTSQVISSKWGEVKKLVPARDNTLQAELQKQQSHTGSCEGSSCSLPLIFPITFLSIALSKFASVVHSITRSPISYTINLFLPLRLLASRSPPFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TK40</accession>
    <name>A0A423TK40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001606">
        <property type="protein sequence ID" value="ROT76832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TK40"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="468" mass="51661" checksum="513C949474A26C35" modified="2019-05-08" version="1">MDGSLSSLSLSPTFFPSHSLLSFFPPYFHFSSLLVFFSPSLLPFFLSFSSFLSPFPSFLFLLPLLHPSFPSFSSLFPSFLSFLSFVTTSCFLSPIATLNFPFPPSLFVPFRFSLSSLSLYPLLLLFLSSFLFTSPFALLFFPSLTSSIFLPLPLPSFFSLFSRLLYPFSLLFPSSSLIHIFLLFSHLSPLLLFALFLPNAVFFLLFSYVLLSLLLRSLLSTSSYPPPLSLHSPPAFIPPPLPSYHSILSSSSLPSSFPIFPLPFFSLLIPPPPPPSLPLFPFPLSSPPSSLFLLFRSLFLSSPSPFSILPLYSLFPTSSPLPFPSYYFFFPTVSSSSPFFPSLPSPLSPLPFLPVPPPLPSSFPPHPPFISFFLPPLLPLPFAPPPLPSSLSIFLLFLLSLPPPPPPSPLFPLLFPSSILSPLSFPPPPPLPSPSLHALSLPPLRRVPPVSNYISGRLNVIRRLTVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNK9</accession>
    <name>A0A423TNK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001442">
        <property type="protein sequence ID" value="ROT78054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNK9"/>
    <dbReference type="OrthoDB" id="6370871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="20132" checksum="62E699E4763CDFD5" modified="2019-05-08" version="1">MNILSSTVHYKVARNMSGPLAVVTMMVLIVTVTFLALSNKSLRAALEEERTLSLKSIIKELTAQKTKLTSEAEERAKELNHLQEQAVKNQQMTQEIDTLNARINQLTEDGKQLEGKLQSAQQQVGALEATRKDLSEQLATAQREIADANAKAGNAIPQEQPAPAAQPAPAPQPVPAAQPVPAAQPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPL7</accession>
    <name>A0A423TPL7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative vacuolar protein sorting-associated protein 11-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_002872</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Late endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001387">
        <property type="protein sequence ID" value="ROT78394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPL7"/>
    <dbReference type="STRING" id="6689.A0A423TPL7"/>
    <dbReference type="OrthoDB" id="26184at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PEP5/VPS11 N-terminal" evidence="11">
        <location>
            <begin position="46"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="10">
        <location>
            <begin position="298"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT78394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="44919" checksum="3D956149767CC8C8" modified="2019-05-08" version="1">MSKREAGGEELGTRVLVWFTTPLDRVPPPTRLKTPYTRLGLRCVRCEVTCTAAGRGHVYIGDSTGCVHSLTRQLKLDSFQAFDRAVKSITAFDHTSIIITVADKNDGPSEIKVWAPDKADVHGQPPCLRTLCPDPRPNQAGSRASSGLNQAGKVPKVTALAVHPNLSLMAVGFQDGSVMLYRGEVSRDRGSKHRVLLTVSSSITSLHIRHNTRATHLFVTTKNNIFCINCTARDKETTVELDSVGCEPGCATLADGRHEHFLVARPDCCDQEEVAEILRQYGDWLYSKGNHPAAMDQYIKTIPHLEPSYVIRKYLDTQHIHNLTTYLQALHRSGSATADHTSLLLNCYTRLRDTQQLDEFIMSKDGAVDCDVELGVRVCRSAGYYDHALLLQLNTSYIIITCNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPN2</accession>
    <name>A0A423TPN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001389">
        <property type="protein sequence ID" value="ROT78382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPN2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="43636" checksum="CBF21C78D5C8AA4D" modified="2019-05-08" version="1">MKPFPKRAHPSTQTLDAPSPPLLLPRLTFLLLLFSLLPSSPPPHFLLLFLVLPFQSPTPSVTLFRPPLPFPFSSTSSFSPFPSSILPSPSPILPSPSFLLLHFSPVIIVLPLHLHHFSPILPSSPSPLTHPPIPLPPSSILPPPLHPLPSPSSPLPLPLPIPPPPSPPLPPSSFSLSIPLPSSNPPSPSPSSLSPLPLPIPPSPPIPPNISNQTAEPHSFNLNSSDQHCPTNINTRKPSALRFSTDSLPLLLFVSIVFLPLFWFSPSYPFYSLALSVIVFLPLFVSPHPLLIFPLLVLLSSSWAGGVPLPCLALRWGSLGSEANPAFSFYLPPLPCLACITVILIPSLPRFGSSHFVLSLVSQNQYSASASFISARVQSRAASCTSCHLHEPGGESMSSPEGPATSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU22</accession>
    <name>A0A423TU22_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative neuronal pentraxin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001306</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU22"/>
    <dbReference type="OrthoDB" id="6515930at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="739"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="771"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="827"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="10">
        <location>
            <begin position="24"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="9">
        <location>
            <begin position="239"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT79967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="848" mass="95650" checksum="E69E2D68C4E3E968" modified="2019-05-08" version="1">MLQAECRNSQPRADDAHSRVVGVQQGLWTVPSNQVFLRYNFSVPEDEPVPTLFNYTICYWIRGERAASLFTHVSYAVSDLDANNILLYQGHDRLLAFVNGVYQRVPQAREFPFVPGVWHHLCHVVEEENYAVYWGGKEFVSGKLAGVPGAPLNGSLVIGQEQDRFGGHFDKYQVLFGEIGQLNFWDRTLPLAEIGKMASCGWSGRGNVFSLDTADMEVVGNVSDTRVELGHFCKETPHYAVLSERLTFQAALAQCRVLGGTVPAPSSSYDNDILLKNAEPFMDSCAPGSNWKYWLGIAHKEENDTWISVESGEEAQYLNFAKPYPMRSNLFQCVVLLDDGTWANHRCSLKKCAICHLPTPGVLYLRGFCFDSDCQRKFRVAEYFGGRLVFRGHEDLFIFWSEGDEAWRLHDIDRNVSVARTEQVGRNSYPVGTHRWVAVEQVCDMQKGSVFEMILSTCTDDLFVCSSGDCIERNLRCNLWNDCSDGSDEENCDVVAIGSSYQPHLPPRGPTDAALTLTPTVTLSRIAKIDEIAMSVTLEFFTTLAWRDERLSFQHLTPGKETPVPATQADRMWIPDFQLLDLEGGQPKVLDEKVMITTANNATLPAFNSIERDLTYPGTENDLTVTRQFIAKFACSFNLHTYPFDKQECSINLQLSRAYQDRVSFSLEGWTGTYTGPEELALYTVKGVAFRSTDDARTELSLGFELHRRQGVILLSTFVPSVLLLLVSWAALFLKDLNVSANLSLTNLLVLYTLFSNLLRSVPDTAAVKMIDIWFFFAISLLFLNIMVIIFLDYVAGFFLNAQTGTSPKDTSLEKIRERIMSLYRSAIPFAFLAFNVSYWWLVVFVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUA8</accession>
    <name>A0A423TUA8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">KxDL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KXD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001165">
        <property type="protein sequence ID" value="ROT80020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUA8"/>
    <dbReference type="STRING" id="6689.A0A423TUA8"/>
    <dbReference type="OrthoDB" id="10258877at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099078">
        <property type="term" value="C:BORC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032418">
        <property type="term" value="P:lysosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039843">
        <property type="entry name" value="KXD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019371">
        <property type="entry name" value="KxDL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13511">
        <property type="entry name" value="KXDL MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13511:SF0">
        <property type="entry name" value="KXDL MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10241">
        <property type="entry name" value="KxDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KxDL" evidence="3">
        <location>
            <begin position="32"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="191" mass="21094" checksum="C3720B1F4FBC10E0" modified="2019-05-08" version="1">MNVDQPLPTFRRLGSIECFQNYTAPEVFVQGLAGQINQQDVEAIIRAQKQMLQRFEKTNEMLSNCNALSATRFALAQKEFKKHTALLVDMKKDLDNIFPAQEAVFKEEEEDEEATSASKDQTSSDSAENDAKRASVSGESGHSSKSERVEDMEQSSDGSRADTERRMKKTASSSSDSSSSAKLSSSSSFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUT8</accession>
    <name>A0A423TUT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prostaglandin E synthase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001142">
        <property type="protein sequence ID" value="ROT80218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUT8"/>
    <dbReference type="STRING" id="6689.A0A423TUT8"/>
    <dbReference type="OrthoDB" id="423541at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050220">
        <property type="term" value="F:prostaglandin-E synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12782">
        <property type="entry name" value="MICROSOMAL PROSTAGLANDIN E SYNTHASE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12782:SF5">
        <property type="entry name" value="PROSTAGLANDIN E SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="3">
        <location>
            <begin position="455"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="621" mass="69161" checksum="A3466887F4CA33F2" modified="2019-05-08" version="1">MYRDAPHLSSLIEAVSLSARPSFSLRARHPTVSLVLAPSSFSRSLQPSSLSPSSPVAASSSIPPSLTHSVHPPVHRFLSTPLSPYPFCLRRRPPSPEAGRPVGPVPVPRILSSLSGSPVCRLRLGPLSPLSSLLSSEVPASVVSPLSDLISLLSPSSLPRRPLCCFALLAQLSLRLSLSARCSLVSLQISSLSPLSGPLRPQSLIFSLSLCSRVSFRKSLLLLDLSLSSRRLSCSLSLSFPLPHSSSTLIVESLIWILSLIASLRFGHPVLSRSLRVPTSPPRGLPPSSHLSLFNLARSPLSISSLMSLSHLSHAVDKECIRIPRLRVKTTMNIYVRRVLSSLRQYEPIFSRNTPQTLQRYGVKESPLLRFASTGKTVKSPTKSNAMKRYGKLVAIGFSMGAIGGAAYMYEIYKKIVTPVSNPSEGSEYLLKEKPPTFKPARSIRTPTDTTGLKITLFQYQTCPFCCKVRAFLDYYGFNYDVIEVNSVTRAQTRWTDYRKVPFLVVELPNSDKVLQLKDSSMIVSVMQSFLDNKSENLEDLVKCYPTIEFSDDEGEKRLEIMNRYFLMYGKHPPGRSKDDIVDERKWRKWVDDVLVHVLSPNVYRTPQESFQAFQWFSKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW76</accession>
    <name>A0A423TW76_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001095">
        <property type="protein sequence ID" value="ROT80652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW76"/>
    <dbReference type="OrthoDB" id="6367319at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="764" mass="84853" checksum="590CA5CFDC414BB5" modified="2019-05-08" version="1">MYQLSGFSPLAGAQTTGSAPQFLIEMDSIDAKIQRTWANAMAEMDAAMNANMVMNLDSLMAHPVHYIPDVASKFNKGIKAASAAFMAPWNNAATKAQLIESLLRKPGTKDQFMLQVPQDRKVYIRVQSAINAFISTWQEAQNPLSILEKEMLLSPDADSSSEKTEILVSSWQASVQWLRDLRVKVTICMRPNVASTKKTEALEDIEKIMSSFIDSWKKAKGSVNDIQPFIYKVAEVKPSGSSVPNSDMPIFMPSMEGATDEFTKAWGIASSDFPDMDKVLSTIKFPDIEEPEMIDFATQEAVAKFMGSWNSALAKANTVQSGLIRLENNGRVSVKIPDQVDLSTSIQEAIDDFTDAWKRAKVSIVIFQQLFPNFSKNTATSLMHHWDDAAQSLSVIQRSLTISNSPEYGTSERRKASRQVAKAIYAFIESWTSATEKAREIHPQVYKLVGMKPSAVPVGIAPVFMPSKDSSSEFQAIWKFMVAEFDGFDKMMDEISIPKVSVATAPPKIFSLIDEDLSVQKAVTGLMASWNIASQSLDQIRKSCLISEKEKSFAIPSDKTERNTLLGAINTLMAAYDTAIRKVYQFETVILDLSEEEDGVKELKRNLAEYLYSWNTAAKRIQIVREYLTINPFLCKRCLDMKVIPEFFAACHEASLRVPKIETAFYALSGATSLDTCAACLTATSVSVTPNTKVAKKKYVAEFNKSMAQIPKTKVTTVLPVPSKFSRHVQSYSFSIRSFSSSTQTSNRLFAPVRDLPIYVEGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXG4</accession>
    <name>A0A423TXG4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_000118</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoethanolamine + S-adenosyl-L-methionine = N-methylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58190"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:20366"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001015">
        <property type="protein sequence ID" value="ROT81127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXG4"/>
    <dbReference type="STRING" id="6689.A0A423TXG4"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="9">
        <location>
            <begin position="190"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="42235" checksum="4136F8A9F2BD16D2" modified="2019-05-08" version="1">MSSAKRMMLSTQALSPAEPLRLLAEYSLTLLPFRCDTEVPRLAQEADHVTFVFPSKGGNSVEMNKSSDKVTYKCDDVTELSFPPSSFEMVVGAWVLSGLSDLQANDFLHRVLDWLVPEGHFVFREACGFHEGWRGYSATLGFQQEANLQLGTAPDSRLTDSRRGTAQIGRADIGGQEFCQRLGLQPGHKVLDVGCGTGGSPFFMSRLSSTMIDLAVELQTHLQRVHRKRVHFEVRDILNADFDGCIYDVIYSQNSIYHIAKKEELFAKLYVTVTDYCVKSTQPSEACADFAAKECSTLLTISAYERGLSKAGFSVESRDLADDFCSIHQKELDAFLSTREGFLEECSQLEFEETVAMGTNKITLVKTGQLTWASFFARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0I4</accession>
    <name>A0A423U0I4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000860">
        <property type="protein sequence ID" value="ROT82207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0I4"/>
    <dbReference type="STRING" id="6689.A0A423U0I4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="505" mass="54797" checksum="FFC462DA73E371AF" modified="2019-05-08" version="1">MIFAGSSGNWIFRHVTPSSFASPSLTLAPSIPLPFHPFLSLFFFICFLFDPQTSHYLFSLLFFSLFTSSFSVDLLSFPPLFLPPSPSPLLSYILPFLLSFSPVSPSSLPLLLSFSFLPPSHPRLSSSPSPSFPPSSSPSPLVSSFLPPSPPLLLPSFLRPPPPPPLLSSLLSFSPHTLPPSPPLPPPSPSPHTSLLLLPSLSLLLRPPLAPSLPSNTWPTRAHPAPSSYPSWNSHPRSLSPSHVIILLVPIPLAILLAALARNYSSPLCSVFIISSPPLSPQTFPRSSTPPQTLPSPPQAHPSIVLSPLPPSQLPTTLPSLSLPVTTSHPFHNFHHPSFLSTHPVTTIFIHFPPRHTPSSSRLPLSQFFITHHPVTTVLPLRPSPPIAPFALHNLPSPPIALVTTSSPRTTSLRAYTTSLRPLRPRHKYRPRHNLALSPRHPFAPIALVTTSLRPLSPSSFYRPRNLPIPSSQSPSPFATNLPVPPPHPVTTLIFSVPFPSLPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0M5</accession>
    <name>A0A423U0M5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative acid-sensing ion channel 4-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_024585</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000853">
        <property type="protein sequence ID" value="ROT82256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0M5"/>
    <dbReference type="STRING" id="6689.A0A423U0M5"/>
    <dbReference type="OrthoDB" id="10051479at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT82256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="340" mass="38683" checksum="953966A8D43A8223" modified="2019-05-08" version="1">MDIVMQLRCELLIYSLLPLTAAIWYPQNGKRFRTQLTFDEEIKSSPLTDLSSKNCFTIFGDLDNEMEDEFIISYAGAEGGITLIMKTEVGDYPGSGLAESTGFLVQVHYRYENPNAFHSGFLVSPGTETRVVLTVHKTERQPKPYSSQCVSSWNETGFEPLLFYSTENFKPSYENYSKEECSHMCSHRKVMQLCRCYQSSERINFNTKDLDVCMTKEEGNCASKVDYELLPDKEKDCNCRPECSLFGFDSRVSTAPFPTPNYRSAFMNKYNFTDGQEATKLVVYFSSMEVEVQREEPRYKDYAALLSALGGVLGLYLGLSLLVIAELVLLLVKGILWCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1A5</accession>
    <name>A0A423U1A5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000818">
        <property type="protein sequence ID" value="ROT82470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1A5"/>
    <dbReference type="OrthoDB" id="6398195at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="28270" checksum="24614F63AD9162BC" modified="2019-05-08" version="1">MATMQMFGRTGNKKTGIILAVIGGLMFAIGIALVITGAALPCSFDEDDWDYDCNSKLPLFITGGFMLPFALIILGLGLTIICYIRHASLITSVSTRTDMHISHQYGTTTVSAQRTVGNSPYPQQAAVPPYPQQEAAPPYSQQAAVPPYPQQEAAPPYSQQAAVPPYHSSKLHLTHSMIQFHHTTHKRNPVRHTHSRQQLQHIHSRQQLHHTHNKQQLHHTHSRHQFHHTHSRPQVSHTNKAQDQPYPEKSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4Y2</accession>
    <name>A0A423U4Y2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000637">
        <property type="protein sequence ID" value="ROT83754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4Y2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="454" mass="49097" checksum="96D6E121EDF914A3" modified="2019-05-08" version="1">MTRKHIKRPAINSSPPPPLYFLLSFLSPFEILPLLLPHFLIFLFPSCRALSLLSTIFIFPPHFALPPLLPSSPSAAISLSVRSSLLISSPPFISFLNLTLILPHLPFLLFSISLSFPTQTSPYPPLLHISLPYPSLPHSRLKPSFSPFLAAFLFPFLLPHLPSPLSPPSSSPPQFSLFLSLPRSLSLPPSLLHISLSLIPFSSLSPAFTSLFLSLPRSLSFSPSLLHISLSPLSPSLPHSPTLHFLSLSHSLPSRAFPYPLTALAHLPFPLICPSLPHLPPHLPLSLPSSQPFLPPSLSTSPFPLTPLPPSSHSPASPPSFSPSSQAFPYPPLFLQSPLSPLSPPSLISQLTSSLFLSLASQPSLPPLFSHNLPFPLIPSLPHSPASPPSSLPSSQPLLPPSSSTSPFPLTPLPPSLISHLTSLFLSLPRSLHDAQRWHDRRSSINFTAGITDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U806</accession>
    <name>A0A423U806_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase</fullName>
            <shortName evidence="13">GNT-I</shortName>
            <shortName evidence="13">GlcNAc-T I</shortName>
            <ecNumber evidence="13">2.4.1.101</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_021966</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11456"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="Rhea" id="RHEA-COMP:14368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60625"/>
            <dbReference type="EC" id="2.4.1.101"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">The cofactor is mostly bound to the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyltransferase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.101" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01000489">
        <property type="protein sequence ID" value="ROT84844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U806"/>
    <dbReference type="STRING" id="6689.A0A423U806"/>
    <dbReference type="OrthoDB" id="6361914at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003827">
        <property type="term" value="F:alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047223">
        <property type="term" value="F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004139">
        <property type="entry name" value="Glyco_trans_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039477">
        <property type="entry name" value="ILEI/PANDER_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052463">
        <property type="entry name" value="O-linked_mannose_GnT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396:SF1">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03071">
        <property type="entry name" value="GNT-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15711">
        <property type="entry name" value="ILEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52031">
        <property type="entry name" value="GG_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ILEI/PANDER" evidence="14">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF15711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT84844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="63588" checksum="A7CEFAA8C2582DB7" modified="2019-05-08" version="1">MSSADKVFMSLNKREIYRNLQDRGIHAVVLNQHSGRVTAKRVFDTFSPGVEEELVEFVDDVQDGRIIVFAVLDEASKGLTWRGRNKLRELGSRWSEKIAYRDMWALVTRKGGLKLAETYSNVATADTGYEWGGPCSSGRTSTSRRTSVTACSWADERNEARRLFCRSNDGYGAMCDCDVTSWKDVFFHADDQLHKNLASKQLYKDLGIAILATDRPHYLYRTLKSLWEAPGLNRDKVAVYADTHHQGIMDVCKLFGVHLVVAQQPGNSSAIRIRNKFQRILGDLFMAKFPEGTVPPEDTSKDAVPPFACTSILILEDDIEVSVDIFKFLHEVSPIMERDPTVMGISSFNFFGFRDVANNLTQLYRTDQVNNLALYLTSKVVHKELAPKWMPVDSTREWYRALIDVVAEKPGRAIVYPEVPRARHRAYSGITINGGVQYNLFRDHVLALTTDYQFQKEEIERLELSQYEAWQLNTLKASEPISFDFCKHDFLYSHDPVIMFVNHNDSREGESDWHYAMKCLKTWDIYMEAGWKGVWQFHFHGHLLSVVAYPTSPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9T8</accession>
    <name>A0A423U9T8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transgelin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013682</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calponin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000271">
        <property type="protein sequence ID" value="ROT85466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9T8"/>
    <dbReference type="STRING" id="6689.A0A423U9T8"/>
    <dbReference type="OrthoDB" id="21595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000075">
        <property type="entry name" value="Transgelin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050606">
        <property type="entry name" value="Calponin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000557">
        <property type="entry name" value="Calponin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003096">
        <property type="entry name" value="SM22_calponin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385">
        <property type="entry name" value="CALPONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47385:SF14">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00402">
        <property type="entry name" value="Calponin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00888">
        <property type="entry name" value="SM22CALPONIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01052">
        <property type="entry name" value="CALPONIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51122">
        <property type="entry name" value="CALPONIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="23"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="20382" checksum="A5214CAAFB536943" modified="2019-05-08" version="1">MNRATKSGIAAEAQAKVNAKYSEEQAAECLEWIAIITSADINKSGDADNFYETLKNGQLLCQVINALKPGQIKKIQTSAMAFKCMENINAFVEGAKACGVPTQETFQTVDLWERQNLNSVVICLQSLGRKGSQFDKPSIGPKESEKNVRHFTEEQLRASEGIVNLQYGSNKGATQSGMSFGNTRHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9Y2</accession>
    <name>A0A423U9Y2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000260">
        <property type="protein sequence ID" value="ROT85500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9Y2"/>
    <dbReference type="STRING" id="6689.A0A423U9Y2"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="19539" checksum="59AE9F86A843CDB5" modified="2019-05-08" version="1">MSLAQGAPLLSRLVSSSVAIASQAGHSVRDLQTEADRAAQRCIISSLNKCFPKITIIGEEGEDETTVASGSIFDPSTTSLVDVTCPPHLSSMAEEEVGAAVCSQHGGPLNLSESGDGESGGAGTPCHGKHARTLPRTFSEWNDLCDVRDDMKTAYVCWPAATTLLQAATIASLYGADQWLCQTFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB75</accession>
    <name>A0A423UB75_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">EGF-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_003532</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Extracellular space</location>
            <location evidence="2">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fibulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000148">
        <property type="protein sequence ID" value="ROT85947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB75"/>
    <dbReference type="STRING" id="6689.A0A423UB75"/>
    <dbReference type="OrthoDB" id="409374at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000009">
        <property type="entry name" value="Low-density lipoprotein receptor isoform 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000037">
        <property type="entry name" value="Signal peptide, CUB domain and EGF-like domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000240">
        <property type="entry name" value="Vitamin K-dependent protein S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052235">
        <property type="entry name" value="Nephronectin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24050:SF27">
        <property type="entry name" value="FIBRILLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24050">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00907">
        <property type="entry name" value="THRMBOMODULN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 15" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="4" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="197"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="277"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="317"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="415"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="415"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="483"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT85947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="521" mass="58272" checksum="72353FC3BA8A3C21" modified="2019-05-08" version="1">MPSSFSLLPLASYVGIHTALGPDKRRCDPADPCHEKNGGCQHLCENVSGQPRCSCPRGLKLEDDQRTCTDEDECQTPGTCSQRCHNAFGSYSCTCDQGYQLAADGRSCYKIEMEVVNPCHTGNGGCEQICEHGPEGAVCSCNAGYVLGSDGRTCVDVDECQAGSHRCQQECLNTPSGYACSCKPGFTLSSDGFSCTDVDECRERNGGCEHFCRNNVGSFTCSCREGYRLVGRTRCLDIDECRENNGGCEQYCRNKPGSFECLCRRGYRIVDRTRCLDIDECRRGNGGCEHQCLNTPGSFTCSCPPGFRSVDGKRCEDVDECQERTDGCEHYCRNTAGSFTCSCLRGYRLVDDRRCEAVPTDLGQDIAVSQRGQVDDVTENGLQILEDDFTDLTNDLTVVETERSWTVDEKGTWRIEGDRDSRGRGKTTGMDDRRRGPGEGEGQRKGQDAVDDRRWKLDEGRRWETEGQRPLRPGGGRGDEDESRYNNVDRDGRWRIDEERRGKGERWKKMEGRRRVLHENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSA8</accession>
    <name>A0A3R7LSA8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_019046</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01003496">
        <property type="protein sequence ID" value="ROT63082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSA8"/>
    <dbReference type="STRING" id="6689.A0A3R7LSA8"/>
    <dbReference type="OrthoDB" id="302728at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="80"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT63082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="272" mass="30922" checksum="0F4D8C61AC3AF2A7" modified="2019-04-10" version="1">MPRSFADFCAVVFMCFAIPAIYVFEVFIVAPTIYNATLSVLHGIAGTFIVANIIGNFIAIMLVDTSTQGLLLPSQVPSGWHVCAACESTAPARSRHCNTCNVCVLKKEHHCVFTGCCVGLKNHRYFYIFLFYMWGSTLYCSFLNAFFIWPHVGGFSMWAVVRLLLPGVWILWEPSLDTLYAFLFSINVIGFLFMTVLIFYYTGLLVTNTTTYENNNRKGQKYDHGTEHNIKVTLGERWYLTWIFPTISSPLTYDGLDWSNQISSRSVRPKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVB6</accession>
    <name>A0A3R7LVB6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_017988</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:36684"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01003329">
        <property type="protein sequence ID" value="ROT64084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVB6"/>
    <dbReference type="STRING" id="6689.A0A3R7LVB6"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12349">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12349:SF2">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="67"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT64084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="34955" checksum="5484B730E0F357C3" modified="2019-04-10" version="1" fragment="single">CTSLYLKWGIYVPVYQGVVTLFVVLNFSLATFMDPGVIPKASTDEDRDDDFRAPLYKNVEINGITVRMKWCVTCHFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRYFFMFLCSLSIHMISIFTFSLIHVLDKKDSLTETTTIVSMVVMGVIAVLFIPILGLTGFHMVLVSRGRTTNEQVTGKFRGGYNPFSRGCCRNCCYILCGPQYPSIKRPAKYIGRYRFTPSLSPPAPVSTITSQSQVRVYMDNGVQAPNSTAYSQDTAGLIAQDNVSTVHDMSNVHDGSHGASTPCMYSKEAVVASNLVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LW28</accession>
    <name>A0A3R7LW28_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003216">
        <property type="protein sequence ID" value="ROT64650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LW28"/>
    <dbReference type="OrthoDB" id="6365616at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="636"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="689"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="838" mass="90487" checksum="3B074670AA846708" modified="2019-04-10" version="1">MDASNEFKVFLSPSSASAAKKPEGESSNIRQRLVPVINKVFSPSHFMLAQRKTTVYKAVSGVSFQDIELGGKRKSGTKREKKEKRSDKKDDIYTTASEGDKSQASGRSDKSGGGGHGSKAEARRHRHSLGSHAERPQSFLNDNLEKLSLDKKPRVRSASRTRSASATDNLYLSQAAGESNGQGDAPPIKPRRTRSASRPRKALSTVPVPSLTSTSSTSKASSSSGDGRSRQDQRKENGDKQSEKKSGRSNKSENSGERQEAEKDSKSKGELKAKEGEDEEPEGGYFSLEKEEKAAGEIKFIYEAVPTNSCEEYLENDQCVEAIYVCQVFRKDSDTEGDDDHVYENYQVIKMTKEGKLITDDDENYANYQIIRRVKEAELLGLPDAGDGGGEEDDLYESINFLSQNPLALVQTTATEARMKRRPRLGSSDSIPFIDDSDNSGDETVTRNPVARGVTPGGSVTVITIKDDDKTEITQKVAGPLRTKTSPLGAQDGPDAAEAEGKGVHGEKLAEASDRGRQTQSEARSKQKRSSEPSASGATTASSAGRGCHTAPSRHSYPAASSLIPKLADKVGPNATRLAPASEEAGGSVAGAKDGRQKKVKKSMSHSDVQSHFKGKSGLTLSESFSDDDIQHNEDFESFSETDSELDNLDYDMFTPKSSRSGQGSRPPLRRARRLPRGRSLSASHASPLMTSTPFGTCRNSSGSSAVESTVVLGEELQSPKTFQALLQDRCLNPPETDAESQAGDSKTDKGAPLLIRETGDVSVRGARDVVMSYHSVGAEAGDRVIVDDTLSFTWSDAESEFEFIDFKKAEPPKTKGSAVKRSHSMKGKPTDAALDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZ84</accession>
    <name>A0A3R7LZ84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002829">
        <property type="protein sequence ID" value="ROT67259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZ84"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="461" mass="50126" checksum="14B3FC5A45E3CDC1" modified="2019-04-10" version="1">MMADPDQTLARWWYVSFDTIDIAFFVITSPFSPLLFILLSFFFLPLPSPLISLSFLPLPLTLFPSFSLALSSPFPSFLSPSHLPLLPSLPLSPFPPFSLLPLISFPLLSLSSFLSSPPLISLSSFLPSPLPHLPFPSFLPLPSIPFPSFSLSLLHLPFLLSPSPSHLPFLLSPSPSHPTPPSLPLSPSPSSSPFPSFSLSSHPLFLLSPSPLSLLSSFLLSFSPFPFSLSSHLPFLLSPSPSHLPFLLSPSPSHLPFLLSPSPFIPFPSFLSLSLSSTFPSLLSLLLSPSPSHLSSFLLSPLPLHLPFLLSSPLPLISFMPLPLPLSPYAIPSPSFISYAILLSPPSSPLCYSLSLSLPSPLCYSLSFPFSFSSFFLLFPLISLSFFLPLPLISLMLFSLPLPLISLIYSFPLPLILSFFLLSLSSPLPYANLSPSPSSSLFLFSTPFGLKNQPLTQRNIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M982</accession>
    <name>A0A3R7M982_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase</fullName>
            <ecNumber evidence="4">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_005979</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001772">
        <property type="protein sequence ID" value="ROT75486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M982"/>
    <dbReference type="OrthoDB" id="6353658at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001613">
        <property type="entry name" value="Flavin_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF410">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00757">
        <property type="entry name" value="AMINEOXDASEF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="5">
        <location>
            <begin position="99"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="120"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601613-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="546" mass="61358" checksum="C15D7B9F595F8859" modified="2019-04-10" version="1">MRLRKTSVGHRQVFGRLLFVLARSGRHFHGVSHRRCRLFRILCRRNGLDDMVVHLLSVLAFMCQTLALSSSHPCDIDENPAAWITNHIKKDVVIVGGGVAGLSAAKELLAAGISDVIVLEAQDYLGGRVKTYREGDILTEDGAEWINGGRFNPLYGLAADLGGLTMPLPDTAYDWRAKTQSGEVADARGYDAAAWVMEECERDSVLQNYLDKGYGECYENKFPGAYDWEMARPAEQAAWLHYTEMWVNKDTGLVDWKDISGLDADHFTDWGLDEWNQWADGFDTLVNYLKADIPVANMKTSSPVCRIFYGRKVAGKRLRNRVLVVTQDGTSYLAHHVVVTASIGHLKERHDRIFTPALNSAYRDAMAVTELGLADKVQLGWDSPWWGNDPLDLQVIFTEDLPGEMSWLQGIMEFMTIHQQPNMLQAFVPGNYARQMEALPEDTVKQHLVAHLATVTGQTVPPPTFFRRSLWEDNVWMRGSYNSYVTVEGALSVMPNRSPLARTVRRNGKPLLLMAGEHTHTTRYGSVDGAMATGVREAKKIIRYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9L7</accession>
    <name>A0A3R7M9L7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cuticle protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010861</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002380">
        <property type="protein sequence ID" value="ROT70842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9L7"/>
    <dbReference type="OrthoDB" id="6355773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF196">
        <property type="entry name" value="CUTICULAR PROTEIN 72EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="24237" checksum="754FBCC118504926" modified="2019-04-10" version="1">MESESEKARGRGRETTYPDVEGRTTPIPSPSADGLDVRRYIRDGCRFSRQTAPRRWVNMNALTVISVAAFVASSSASLLAYNGVYGGHHGLLGAYPYAGYSGLHPYSYAGVLPAAAPITLKTPVVKTVAPTPVSYNVAAAPLAYNVAPFAPVAPIQSQYHAQDEIGQYSFGYAGGPSTRAETRDAFGVVRGSYNYVDSEGKVQTQHYVADALGFRVSGTNLPVAPDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAY5</accession>
    <name>A0A3R7MAY5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein fend</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001470">
        <property type="protein sequence ID" value="ROT77815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAY5"/>
    <dbReference type="OrthoDB" id="6341493at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="446" mass="48668" checksum="0E7CFE291B2933CB" modified="2019-04-10" version="1">MAQCRAHCLDKFEKDSSLQDDASCHQNSNCFMCWENCELLATNYPIWSITCGQRDICGEGCEAACNFHSAHPNSVVPLSQHNSRLTLVFSGWAAQWTLSWGRSAAQEHVVFALFTRTPGKSWDLRLQTADFGTALDDLPTGSDMKLVAVAESGVLSVIITPYAPPAHPRGSVKPTLGSSREQSSQEIPENNSIEMDGSDLWPLLHEAEVEDSGLVAARVWWAPQNPRGGDYLVTWEVEGGGLKGHLYTDLPEVDLTLWPETVYHVQVELVTGPLGEPLRSAQLTLDTHNITLAAQQKQNEITPTLPLVHRFVTPVQLEVVLGVGAGVLAALLVVVILVWRRRQASALTYETSSTASTTKWGAWNRTLSDLTLDESLVVKSHKFPESAPTHSTPVRPTNAPVFTLPPPPGSTSTSLLTLGRPAQAQVNLYSVVPPLLDHNNGKISRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD64</accession>
    <name>A0A3R7MD64_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001241">
        <property type="protein sequence ID" value="ROT79453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD64"/>
    <dbReference type="STRING" id="6689.A0A3R7MD64"/>
    <dbReference type="OrthoDB" id="6379141at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000003">
        <property type="entry name" value="Transposon Ty3-G Gag-Pol polyprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF454">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="68"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="269" mass="30693" checksum="92421BD5F566AAF9" modified="2019-04-10" version="1">MCRLTGDAYWAIFSDFPAVFKPELRGTNPGAAAIHGVYHHIKTTGPPVHSRFRRLRPEMFHAAKLTFTEMVVCSKAASPWPSPLHMVWKPNNSWRPCSDYQRLNLITELDHYPMPNINDLRASKDNALIFSKLDLLKGDFQVPVHPDDVPMTAIITSFGSYVLHYSTFRLRNSSATFQRMMDQIFGKLPFCVVYVDDILIFSRNHQEHQQHVQTILHLLKQNGLVVSPDKCIFGASSIDFLGYKIHRPIKLTLCSSSLRQHLSRESSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDA5</accession>
    <name>A0A3R7MDA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001228">
        <property type="protein sequence ID" value="ROT79536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDA5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="478" mass="51702" checksum="77B71C3516ED935F" modified="2019-04-10" version="1">MAVNSLPLNSFRLTGSHSPSLTPSSFPHSCPQPLPLLQSASLTLSPSSSALLPSPLLPIALVPFSFQAYRYVALPLGYLPFPSCRISSFPCPPLPYPILLLPTSSLVLTGSLRAPPFAPVHVCRSPAASGRHTSSYAFLPLLLPLALPAPPPFPLSCPYALTLSPLRLHPLRPSLSSYLPPCPARHSLVPVLSFPSACLAFAALPATALTLLAHPLTVSRLPLPRTPSPFLPQLYPYAPLPYLSPSSPPPSLPLSVAHKRLTLLHFLSRSPPSRPLPSPTSSFLLLSLYPLALPLLLPSLFLPRVLLPFSFLTLPRLPLLLPLSFWLPVALPFSFPYLSLPSLSCPFPPRPSFLSLTRSPPSASSSSLPSRMPLLHLTPRHDRPFLSLPLRLFAHSALRSPYPLIASLSPLPPSPFCFSLPYPQIALLLLPYRCSALPSSSPSSLFALIYFQLARLSILIATLLSLFIRLATNSRSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGS4</accession>
    <name>A0A3R7MGS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_025497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000990">
        <property type="protein sequence ID" value="ROT81315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGS4"/>
    <dbReference type="STRING" id="6689.A0A3R7MGS4"/>
    <dbReference type="OrthoDB" id="6374771at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010564">
        <property type="term" value="P:regulation of cell cycle process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039893">
        <property type="entry name" value="CEP120-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21574:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 120 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="174" mass="19299" checksum="9FE51D01A109130A" modified="2019-04-10" version="1">MLGRAVDLPQLAGSADELRASLTSLTRFGLEKIEFSCLTPLFLPHFSGRGWRPKNGHTAIVTAKLGTHVVTTDPVALTSDPQFYTELSWELESQIIRRLKVDHVPIRVECHSISKRGKQECLGYIIMPLATAVLGVESDPNWHKLLGGPSVPHKKPPSIRLALCLRNTKVRLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI52</accession>
    <name>A0A3R7MI52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">5-HT1 receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_023594</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000715">
        <property type="protein sequence ID" value="ROT83232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI52"/>
    <dbReference type="OrthoDB" id="6375351at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004993">
        <property type="term" value="F:G protein-coupled serotonin receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071880">
        <property type="term" value="P:adenylate cyclase-activating adrenergic receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043410">
        <property type="term" value="P:positive regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF199">
        <property type="entry name" value="IP13425P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT83232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="143" mass="14927" checksum="797B139E297199CB" modified="2019-04-10" version="1" fragment="single">MFVMNFTLRTTVDTLLQTRVNLSKALDPLTSPAGAGGSVLGLDVDPSDVGLGIGMGSLVTLDDSFWLAGGNDSANQSHFFGNETSDGLIVDTVGMVITSVILGIMILTTVIGNVFVIAAILLERNLQQVANFLIVSLAVADLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKR0</accession>
    <name>A0A3R7MKR0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Solute carrier family 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_022525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000567">
        <property type="protein sequence ID" value="ROT84289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKR0"/>
    <dbReference type="STRING" id="6689.A0A3R7MKR0"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="3"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="83" mass="9047" checksum="66E9B13501745938" modified="2019-04-10" version="1">MGEQRLAKWYFGGLASCGAACCTHPLDLLKVHLQTQQVASMGGSQMAVHIVRSQGLLALYNGLSASLLRQITYSTTRFAIYEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKX2</accession>
    <name>A0A3R7MKX2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003255">
        <property type="protein sequence ID" value="ROT64406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKX2"/>
    <dbReference type="OrthoDB" id="6377329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055251">
        <property type="entry name" value="SOS1_NGEF_PH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22697">
        <property type="entry name" value="SOS1_NGEF_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="644"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="761" mass="86095" checksum="4CBE078B242854E6" modified="2019-04-10" version="1">MENRTRRHLCILVGQMEVPQSVISCRSEETLQLSRRCYDAVTGRGAADVFGRVERGCMAVEVVIAPSHVTVKHGDQLINSIRLQELRLLMAMRSPGNHVVAAGYCQHAQTSVALVFEFADVELANIFIKDYQGCSDSMNREVERERRRKKRRRGERKGEREKQRGGEREGGGRREGEKEEWRERYTGREGEKDKGRDAGREDIQPKSPPRRTSVELSKHPSLSGVCAAPANSQEKLRETAISKPPIPPRTRMYCQEKPAVPSRNSVVGGTYKPTLPRRDSGVEQISPIAATAKPPLPQRISDTTSKIPPPLPRRGAKVAEICEAVASSRDTDSKIPPPLPRRATEAPENCDAAGSSKSHSPRFHMLNPFSKKERKGEESPEGQNQGKKGLFLRKNIKYENVEFQVEKKIETVTPSPIDDKEFADYEFPDSDDDSYGNFYGSFDRSVEDSERIFCHETVPHAEEKDKQTSSQADRINYFLTHEYNYLTSLSYIKAARTLSPELQPLLRGVDTLEELHHDLYRELYSSCQSYSSIAQALLSRREQLESYKYHMMNGPLIYAALAKVPETKLKDHPNLKDSLRISWKRLHFYFMSLEEFLASAPEGDKGVMQEAVAMLRELHALGDSAILIDGVKGTPFDLHIKGPLLLHGSFKIKGPEMQKKDYRALLFAEMLVITLPEGWTSRYQCSLRIDQLIPISQKSDSVSSFTVQVSDGGGKGKLYVFTARDEKTKEKWFNEITKLAAKIADEVKREFEKRYGMKPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPU8</accession>
    <name>A0A3R7MPU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002867">
        <property type="protein sequence ID" value="ROT67003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPU8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="46447" checksum="D3EB0201EB04D37B" modified="2019-04-10" version="1">MLKCFLSTVDVSTVQVVKNHRFGPFLLMYHLGVVVSASLGEPQPTAQVQIAAFRPPPSRQRPGKGGSFTKTECPRWRGHARASTGTSKALATGFGDNHSLVTAVSMATPHPPSPSSTTSSFFLSLPITFLQCLARPTFSLLSLSFLLSLLPPYSLSHSPFPTPSFPFSLNLTFHLALPPSPPSSASTTTFFLSLHSFLSCLLPPRSPSSLSSITTSSFLLPSSPCTTPIFSLLFHSSSSPLSIRPSFPSIYDTILLNLPHHFFLSLLHTHSFSLLHPSPPLFFAPHPPSAPFAVSSSPSSTPYSFLSLLALSFFLSLRHSYFFALHHTLLPPLPSTTSTFSSPPPPPPPTTTTPSSFSFLPPSTTPPPSSPSTTSSSFFSSTTTTLPPSPPPPHPPPSSSPPPAPPSFPPPPPPPPPSPTRNRNSAFRTRQTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MT88</accession>
    <name>A0A3R7MT88_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000301">
        <property type="protein sequence ID" value="ROT85348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF3">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64518">
        <property type="entry name" value="Phase 1 flagellin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="860"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1462"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1739"/>
            <end position="1769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1818"/>
            <end position="1886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1947"/>
            <end position="1968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2113"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2195"/>
            <end position="2216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2343"/>
            <end position="2363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2573"/>
            <end position="2674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2741"/>
            <end position="2802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2826"/>
            <end position="2881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3000"/>
            <end position="3028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3055"/>
            <end position="3093"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3204"/>
            <end position="3230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3252"/>
            <end position="3310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3338"/>
            <end position="3386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3411"/>
            <end position="3472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1463"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1485"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2199"/>
            <end position="2216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2345"/>
            <end position="2355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2584"/>
            <end position="2674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3000"/>
            <end position="3021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="3060"/>
            <end position="3073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="3080"/>
            <end position="3092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3440"/>
            <end position="3464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3491" mass="396479" checksum="D85AD7A2A5B64FDB" modified="2019-04-10" version="1">MRISSQTPQRLLRLCPCRRLLYCLCYRHPQPPLLLRPPTRRLLRLRPQPQPPLLLRPPTRRLLRLRPQPQPPLLLQPPTRRLLRLQPQPQPPLLLRPPTQRLLRYDHSHNHLCYYDRRHDDSCGYDHSHNHLCYYNRPHDDSCGYDHSHNHLCYYYRRHDDSCGYNHSHNHLCYYDRRHDDSCGYDHSHNHLCYYDRRHHDSCGYDHSHNHLCYYDRRHDDSCGYNHSHNYLCYYDRRHDDSCGYDHSHNHLCYYNRPNDDSCGYDHSHNHLCYYDRRHDDSCGYNHRHNHLCYYDRRHNDSCGYDHSHNHLCYYNRRHDDSCGYDNSHNHLCYYDRRHDDSCGYNHNHNHFCYYDRRHDDSCGYDHSHNHLCYYDRRHTTPAATTTATTTSATTTADTTTPAATTTATTTSATTTADTTTPAATTTATTSSATTTADTKTPSATTTATTTSATTTADTTTPVATTTATTTSATTTADRRLLRLRPQPQPPLLLHRRHDDSCGYDHSHNHLCYYNRRHDDSCGYNHSHNHLCYYDRRHDDSCATTTATTTSATTPPTRRLLRLRPQPQPPLLLQPPTRRLLRLHHSHNHLCYYTATRRLLRLHHSHNHLCYYNRRHDDSCGYNHSHNHLCYYNRRHDDSCGYNHSHNHLCYYNRRHHDSCGYNHSHNHLCYYNRQHDDSSYNHSHNHLCYYNRRHNDTCGYNHSHENLCYYNRRHDDSCGYNHSHNHFCYYNRQHDDTCGYNHSHDHLCYYNRRHDDSCGYNHSHNHLCYYNRRHHDSWLQPQPQPPLLLQPPTPRLLWLQPQPQPPLLLQPPTPRLLRLQPQPQPPLLLQPPTLRLLRLQPQPRLPLLLPTRRLLRLQPQPRPPLLLQPPTRRPLRLQPQPRLPLLLQPPTQRHLWLQPQPQPLSTTTATRRHLRLQPQPQPPLLLQPPTSRHLRLQPQPQPPLLLQPPTRRLLRLQPQPRLPLLLQPPTRRLLLLQPQPQPPLLLQPPTRRLLRHNHLCYYNRRHDDSCSYNHSHNHLCYYNRRHYDSCGYNHSHNHLCYYNHRHDDTCGYNHLCYYNRRHDDSCGYNHSHNHLCYYNRRHDDSCSYNQSHNHLCYYNRRHHDTCGYNHSHNHLCNYNRRHDDSSGYNHSHNHLCYYNRRHHDSCGYNHSHNHLCYYNRRHDDSCSYNQSHIHLCYYNRRHHDTCGYNHNHNHLCNYNRDTTTLATTTATTTSATTTADTTTPAATTTAIPPRLLQPPTPRLLGYNHSHNHLCYYNRRHDDSCATTKATPLCYYNRRHHDTCGYNHSHNHLCYYNRRHHDSCGYNHSHNHLCYYNRRHDDTCGYNHSHNHLCYYNRRHHDTCGHNHSQNLLCYYNRRHDDTCGYNHSHNHLCYYNRRHDSCGYNHSHNHLCYYNRRHDDSYNHSHNHLCYYNRRHHDSCDYNHSHNHLCYYNRRHHDSCGYNHSHNHLCYYNRRHTTPVLQPQPQPPLLLQPPTPRHLRLQPQPQPPLLQQPPTPRHLHDHLCYYNRRHHDTCGYNHSHNHLCYYNRRHHDSCGYNHSHNHLCYYNRRHHDTCGHNHSHDYLCYYNRRHNDGYNHSHNHLCYYNRRHHDSYGYNHSHNHLCYYNRRHHDTCGYNHSHNHLCYNNRRHHDTCGYNHSHNLLCYYNRRHNTCGYNTSHNHLCYYNRRHDDSCATTTATTTSATTTADTMTPVATTTAATTFVTTTADTTTPAATTTATTTSATTTADTTTPAATITATTTSATTTANTTTPPATTTATTTSATTTADTTTPPTLRLLRLQLHATHLCLLTRRHYDLRQPQPQPPLLLRPPTRRLLRLQPQHNHSATTTSDTTTPAATTRTTSATTNADTTTPAATTTATTTSVTTTADTTTPTATTTATTTSATTHADTTTLWLQPSHNHLSTTNADITTPVAKHTPNHLCYYNADTTTPAATTTEPNLLATTTADTTTPAATTHSHTTSATTTADTTTPVATTTATTTSATTTRHDDTCGYNHNHNTSALPLTRLATTTHNTSATTYTTPVATTSRRPSATTHRRHHNICGYNHSHDHLCYYNLRHHDSSGYDHSHNQLCYYNRRHDDSCGYNHSHDHSATTTVDTRLLRLTTTATTLCSTTTHDASATTQPRRLLQRHHSRLQPQPQPPLLYNRRHDTLPTTQPQHLLLQPPTRRLLRLQPQPQPPLLLQPPTRRLLRLQHSHNSSATTTVDTTTPAATTTATTPLLLQPPTRRHLRLQHSHNHLCYYNRTPTTPRLSTTTLATHRRHDDSCGYNHSQDYLCYYNRRPHDSCGYNHSHNHLCYYNRRHDDSCGYNHSHNLLCYYNRRHDDFCGYNHSHNHLCYYNRRHDDSPATTTATTTSATNRRHDDSSGYNHSHNLLCYYNRRHHDTSGYNHSHNHLCLHNADTTTPAATTTATTTSATTTADTHTCGYNHSHNHLCNYNRRHHDSSGYNHSHNHLCYYNRRHDDTCGYNHSHNHLCYYNRRHDTLRLQLQPHTSATTTATRLLWLQPQPQLPLLLQPPTPRPLLQPQPQPLLLQPPTPRLLRLQPQPQHLCYYNRRTTTWLQPSHNHLFYTTADTRHLRLQPQPQPLSTTTSATTTADTTPAATTTATTTSATTAADTTTPVATTTATTSSATITADTTTPPATTTTTSATTTADTTTPPATTTATSTSATTTADTTPVATTTTTITSVSITADSTTPAATTTATTTSATTTADTTTPVATTTATTTSVTTTSDITNPVATTTATTTSATTTADTTAPAATTTATTTSATTTADTTPAATTTATTTSATTTADTTPAATTTATTTSTTTTADTTTSAATTTATTTSATTTATTTTTATATSASTSGDATPAATTTTSSATTTADTTPAATTTATTTSATTTAHMTTPAATTTTHHLCYYNRRHHACGNHSHNHLCYYNRRHRHPRLQPQPQPPSATTTADTPCGYNHSHNHLCYYNRRHDDSCGYNHSHNHLCYYNLRHHDPCGYNHSHNHLCYYNRRHTTPAATTTATTTSATTTADTTPATTQPQPPLLLQPPTRLLRLQPQPQPPLLLQPSTPRLLRLQPQPQPPLLLQPPTPRPLRLQPKPQPPLLLQPPTPRHLQPQPQHLCYYNRRHHDTCGYNHRHNHLCYYNRRHDDSCGYNHSHNHLCYYNRRHHDTSGYNHSHNHLCYCNRRHHDTCGYNHSHNHLCYYNRRHDDFCGYNHSHNHLATTTPTTTPAATTTATTTSATTTADTTIPAATTTTTSATTTADTTTPVATTTATTTSATTTADTTTPAATTTATSTSAPTTADITNPVATTTATTTSATTTPDTTTPAATTTVITTSASTAADTTTQEATTIATTTSATTTADTTPWATATTTTASAPNTTDKTTSETTTADTADGAATTATIPPVTTATATTAAATSAGTTAVSHASAPTATAGVTPSDPASGATGSDAATPSAPVGTALPPHLPPAAAAAGPTSSRPPSSDAKRAPKVSLVASHRLSFICRRSFRWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MVB8</accession>
    <name>A0A3R7MVB8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002403">
        <property type="protein sequence ID" value="ROT70634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MVB8"/>
    <dbReference type="OrthoDB" id="6354186at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="573" mass="64214" checksum="D984D0F9B20CB3E4" modified="2019-04-10" version="1">MAELNRTKDAVINSPSYPEGELVCPRPTEEGKNPDVTVLPTPEPLQIKVNSEHHVYLIVNEKEIHGTEKALAIDSESVSDEEGEKENENGDNPASSEKAYSTKTFDDDLTNKVKLIINIEGFKEAGGLLYIGCKNEVEKTNPSKISEWFTADFLNHHRIYAIKEEEPFLLRVFTRNHESTNRGIRKKGGRKVMLMGKEVFGDVLFACGHCGYRSHEGSNVRRHLKKSVCLKEKGYSEEDLVGLDRTERRKFLRRVAAAKFRAKKRAKASKEDATPAVNGTEVTEQQKTMPSNFGSYSLPMGMSNNSYVENLVEIQERCGSDGTNRSGTGLTPQVPNTIVVNSLPPPKVKRKAPKYKALTLGPAVEREVVRRVSYDIFTVNENNERIAWKPPTCHKASPGDRTCQIVFKGARMKRRCMDLPVPMVLIYRKLDCKTHHCCFTLFHPSARIAFKNDSASKASVNIKMYGDIVMTQEFYHYFVSLLSIMKMKSSQTARHLTSVWETIIADRLGSPAIPEEHRKIITLSKQTVKSIWASIEEEAGSRGGLKLLKGPARKKKPPAPAAPLPPLPPAMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N4A8</accession>
    <name>A0A3R7N4A8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Vacuolar protein sorting-associated protein 51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_004463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the Golgi-associated retrograde protein (GARP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
            <location evidence="3">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the VPS51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001592">
        <property type="protein sequence ID" value="ROT76919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N4A8"/>
    <dbReference type="STRING" id="6689.A0A3R7N4A8"/>
    <dbReference type="OrthoDB" id="203678at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990745">
        <property type="term" value="C:EARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007041">
        <property type="term" value="P:lysosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014812">
        <property type="entry name" value="Vps51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT76919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="28610" checksum="24EB9B15300A206B" modified="2019-04-10" version="1">MFLRSPEEGGSGSSNVAMEKLRVFVADLVEQYVAVVGVRVASEPDVGHYGQLTTALDKFHRRLHAITQLLPNTDFGNVALSLVLEAGSARCQSSLAMLKSGLASSLGDIRHALVAPRHPTQDGTESTHRQLNEHLTRLVASTAASIKDKVTALQAFTQPKHTFAVKAEFRRKFCRDLVREGVVVAFFLHITDTLLQFCHKKDKDPVLLLVLSRMCLDLHTSTVHYLLSHCDEQLQLEEKTGLTPLHSITDGMREAGKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N9I1</accession>
    <name>A0A3R7N9I1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vesicle transport protein GOT1B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001055">
        <property type="protein sequence ID" value="ROT80872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N9I1"/>
    <dbReference type="STRING" id="6689.A0A3R7N9I1"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="22099" checksum="372B87560E35F9FC" modified="2019-04-10" version="1">MLMCGADNIEGELTTPCRGGGRRGEELTTPWLPLPPSQAAFANPHLRLIFDSQTFDLPGDVIIFWQAIEPKIGVGFAAFGVTFIFLGVILFFDKGLLAIGNILFLAGLAFVVGLERTFRFFFQRHKWKGSGAFFGGILTVLLGWPLIGMCVEVYGFVILFSGFFPVAVNFLRRMPVIGQLLNLPFISGFVDRIGGDSKMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N9M5</accession>
    <name>A0A3R7N9M5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000299</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001043">
        <property type="protein sequence ID" value="ROT80978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N9M5"/>
    <dbReference type="OrthoDB" id="7480422at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="723" mass="82510" checksum="67B07BD643105D62" modified="2019-04-10" version="1">MSHDARRNEQNEHQRIARLIKTGICPDKWCCVCGYALRRTEDAVKCASGICQNFCHVICLHGNSDFACDQTASLRDLAEEEELLNLPSNQLITIVRNLRAELSRKNSLLTFFNTFSENLASKRDAVVTVLQLIDNIQATKSSIDSLEPTQSVLTRSGVAKPTPTQLRRRGGRRVNHDHLSPASLSLLPFLRLQRQQIKRHKATAIHSHSRNPPTHFLTQTTATRLCNYGNGAHVTRTLSHDIDHATSPQPQRRRTRRPSSQQQHHVSQRQPTQPQRSDKRNSFCQNCKIKGHSQEDCRKNQFCEFCHRHGHEEQSCRTKLSEERQERLFRSLSAEQSHNNNILVQTLQRQLSLLPHLNSGLLRTSWPGVTPHQAHQPYSGWPGATPFVLPLRPDIIATVETFLNHTVPDNFGRIGGYTKWHRKDRTQGTFGGIAVCFKSGLHVQPLQVEMPEHLELSFFKFWKNTQETSLLITSIACFISTTVKNIIIVGDLNQYLVARSFDDLLDTFGLANHVDFPTHISGSSLDPVITDLPDGAVTCQGIAKNAARKLACIRRIAPFLDAKGCYTLYHSQVRPVMEYCPLVWSCCPPSYLRLLDRVQIRAQRLVSHKTLVGERQLHFQPLQHRREVAALCVFYKVHRLRVSHLTSLRLEPRAAAAYETRHSSNRGQELQVPFSRTELHQRSFQPRYSRLWNTMVQQTSLYNLSSLQAFKAAVHRWRSHDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NAK4</accession>
    <name>A0A3R7NAK4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024953</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000908">
        <property type="protein sequence ID" value="ROT81884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NAK4"/>
    <dbReference type="OrthoDB" id="10449905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="625" mass="66822" checksum="0BA5F6D4A2C3BD1B" modified="2019-04-10" version="1">MVPKTAYLELINMASISSQTSGLVLIVGGVVLTLAGGVQTFIAVFMDKPAYFGLFFASGILSLLPGIVVTLVAYRHYTSTSLGLPLGRTAVVVRILLVLSSLILLASVILFHLDFASVWTWAPKESFGVFQDVDDAAVWAVTISGLVGSSSSLICCPVTFNGYHKSSSPVADRITMMSDWVFQPSPTLARSRLSLSGVVAAHRSSRREILHRSFESPQAHNAVSRSRHPDPGVVDPPVHSRCQALNTSTVSDTFPCKEAIIDVTFKSATISGKTAVRSMLSFKPVESSGAAPSPSASMPHLVGILHSRAWSSSPSFAFFEKSEAPIFRMPSTADVSKCQKETAVPAPVTPSPSHENLREHDRDCAAQTSSVLRSRQLSTPSPAHNGLSLITFTPSSNSSSSSGPVTPLSCEVRSTGKKPPYVWPDLSLLIPWKPNISASSSFEHLDIARAEASKTSRPLDASAKNSCNSPSLNVSPFPQCLTSTPAHEMPPTVARPKPAPPPRSEGRSRATKPTPPVRSTSSPEYNSPSPTPSPLLPVVSAPRAEQAPNSAVRGHQFTYTPTTPVGGLLAQRNLKPVPRSYLASSGGSKNNGTFDSSFKTPFSRRSRKSSDSRSASFRSCWTREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NMA2</accession>
    <name>A0A3R7NMA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein phosphatase 1H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003931">
        <property type="protein sequence ID" value="ROT61913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NMA2"/>
    <dbReference type="STRING" id="6689.A0A3R7NMA2"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004741">
        <property type="term" value="F:[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF354">
        <property type="entry name" value="GM14138P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="6">
        <location>
            <begin position="247"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="173"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="676"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="680"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="732" mass="79982" checksum="21D2C50529655D63" modified="2019-04-10" version="1">MLSRFKTALYNVVGSFDPGESNVGALGPGVTSTLPTASGVSRSASQSSSSREKGLRFPYTRPHFLQLNSEDEIQVSADHAIRPIICPRDINRLPWKTGYAETINAGKSKKNEDQAMVHTGLLTRPMRSESSNSRSSPTLSKEQSLSVRNEPFVNGHAEEVEPSKVGAAQEHTVVLSPQGATTETSTNNTKDKKENSNDGKGSQDTNNSNTSGEESRSTNTIRQGVVLQHPLAEPPTPPAPAITSQPDSKTSSIPPSTTPQPPSVSSVSLPYFIFGVFDGHAGWGAAVAAANQLHHIIHEKLCDVIDVLLPDPNEDKNTKSQSPLWLPDKEITVENVVTGALECAFWEMDNVIGEDRLKFQLQGGCTACVALFIHGKLFLANAGDSRAVISRADQPLPMSHDFTPETDNQRIRKLGAMHPELLGGEYTHLDFFQRPLRRDLGRRILYRDHYMSGWTYKTITPDDLKYPLVCGEGKRSRVLATIGVTRGFGDHDLKAQCSSLPIKPFLTPEPEVRIFDLTTADLTDGDVLILATDGLWDITTNEKAVSIVTKSLSHFPAEDHDKYKYRYTGAAQDLVMSARGKLKERNWRTSDDKHATIDDISVFVVPLKPYKEINEEWTLKYKASGGASQKTCEIKNRVGATSSVLSRPVVSILNPVEPTEGLDQCSVAQSDEPVIPESNVAEQNDKSASPSEEIIVTPPVSAADLKPQEDYFRDDSVTEAQTTVPSDSTNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NWC5</accession>
    <name>A0A3R7NWC5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002659">
        <property type="protein sequence ID" value="ROT68541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NWC5"/>
    <dbReference type="STRING" id="6689.A0A3R7NWC5"/>
    <dbReference type="OrthoDB" id="294541at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="433"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="546"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="618"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="666"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="6">
        <location>
            <begin position="37"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="693" mass="77625" checksum="CA91C65C74BD0E58" modified="2019-04-10" version="1">MDPSQAAAEDAAGSPAVRAFPLFGAVSVIIVVLGGTGNLLLVYLSFKKSKLMTAINQLLLSQCLINLTVCFVGIPIKIFLEASGLVFSARDSLCWYLLSWTYASWANFCFSLCLVASVRLLYTVAPLWMHSLQEGRVAALSCGILFLDQLAWFVASVLEDEPPFGSVTCLVEKMEHTSRRIIAAIVFNLTCLLITLGTYLGITFSTARYPLPPPATSRQRNLITARTGIIQCVFFLLTYMTATWVVESMACANAINHCRRMKQLKKRGQVADELVSRTLENAEADQRSTDTSEDHDDHDEELPLITDGVIERTVGEYYAIQEQIEMGQMAKLFYSTVWVKVFYIVLCVYLYGDLAIYEAAVAKSLRDIICDYVPENCTKELLDSDPCFTDSSRSHMSRMEMYRICTFSFVGVMGPFVFFNLTKTKYMQILTTITRWLAMGTMITWAIVLLAEGKNQGHPPAADITKLPQLFGVCVYSFMCHHSLPALITPISEKKSILKLLGADYLLILLFYLLLAFTGIFAFAHLNDLYTLNFQPDRCKDVDTPIAIYCLQVFLLLFPVFTLSTNFPIIAITLRNNLKGLFLRETRRYSFFTSRCLFPLLAIIPPTIVGLVTSNVEFLVGITGAYAGSIIQYVVPATLVHYARKMTLEHIGMGVKNPFSSPLQHYMWLIAICLWAGVCQIFVTLYLVGKDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3Y6</accession>
    <name>A0A3R7P3Y6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transmembrane protein 63B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001848">
        <property type="protein sequence ID" value="ROT74777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3Y6"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="22554" checksum="8C69BBFF9B7DE166" modified="2019-04-10" version="1" fragment="single">MTIIYSVSCPLITPFGTLYMIFKHLVDKYNIYFAYGPSRINKNIHTSAINFVIVSIVCLQLSLLFFSLVRQGLKKDITIYSIILLIITCVVFITHNAFHWFKDLSPVEYKKFGNGTANGDTASVNDDESTTEVACQFVPAVLRDAPSGVESSYDYINQPRSYGTRPRDENGLTNEAAVRSDEDSPRPRQSSLYQDYSHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P624</accession>
    <name>A0A3R7P624_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004872</name>
        <name evidence="8" type="ORF">C7M84_009138</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002149">
        <property type="protein sequence ID" value="ROT72479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001647">
        <property type="protein sequence ID" value="ROT76529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P624"/>
    <dbReference type="STRING" id="6689.A0A3R7P624"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34072">
        <property type="entry name" value="ENZYMATIC POLYPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34072:SF52">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="7">
        <location>
            <begin position="47"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT72479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="230" mass="25789" checksum="BD329863083C3E1E" modified="2019-04-10" version="1">MFPLPSDVTQVKSFLGLAGFYRPFIKDYGRIAAPLMYLLMKDVPWRWDEEQVNAFRKLKNCLSHAPVLAFPKFDLPFILHTDALNIGLGAVLIQEHKGNLRPVGFASKVLTSAEKNYSVTNREMLAIVWALKYFRDIILGYKVMVHTEHMPLTSLNGNDPYGRRAHYQDTLGDFDVTMYIQGRANVAADTQSRALIGTSQPLRRDDAADFPPSFSLPSSTVVNSASQVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6M4</accession>
    <name>A0A3R7P6M4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative CDK5 regulatory subunit-associated protein 3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDK5RAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001592">
        <property type="protein sequence ID" value="ROT76924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6M4"/>
    <dbReference type="STRING" id="6689.A0A3R7P6M4"/>
    <dbReference type="OrthoDB" id="340432at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008491">
        <property type="entry name" value="CDK5RAP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14894">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14894:SF0">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05600">
        <property type="entry name" value="CDK5RAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="435" mass="49995" checksum="967ACD9031D29651" modified="2019-04-10" version="1">MDEQDIPIDIHGHKLLDWLVSRREVKRDWSTKTRIIREKINNAIQDMPEHPEITRLLSGTYINYFHCLKIVEILKETEKDTKNILGWYGSQRMKDWQEITRLYEKDSVYLAEAAHLLMRNVKYDIPDLKQQISKGTHIQEECDRKEAEYIKSAEEARKRYSQMCKQIGIPGEKIEEQQIEIDLDDDDQKADAGEIDFGDVGGTIDFSTADIELAENLTTGDIDWGNLSTEEPQTIDWGVDVNDVATVDIVVEDSGVSGGVAKGTDALTLLYNPKTRAQLIDELFELEGFLKQRLIELESDESSFSINQFSTAPISVQDQSKEQLEVMISYIRNVIDPLSTNKMQHLFLIYSSPKYVDRLAASLRSKLTVADKFVISQEGVRQRRLEAQQEQQKVHPKLATMIERSKELKVNIEEHISKRYKNRPVNLMALSLSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6T0</accession>
    <name>A0A3R7P6T0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001573">
        <property type="protein sequence ID" value="ROT77040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6T0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="101" mass="11076" checksum="49E6D217C8D0B7BC" modified="2019-04-10" version="1" fragment="single">MSSYHSVLVRVRPLRGAVPQHSAAFVGANRRGEENDRGEPQGHHPRHVFVRDSGGVQAWACCQSHGRGGRPWVGQQHGRSAVTVRPGRALRHSHAQVSYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE34</accession>
    <name>A0A3R7PE34_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013962</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002737">
        <property type="protein sequence ID" value="ROT67926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE34"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="555"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="593"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="625"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="669"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="755" mass="84719" checksum="63F97F8FB293750E" modified="2019-04-10" version="1">MHLLHLLYSGLELPGMHLLHLLYSGLELPGMHLLHLLYSGLELPECICYTFWLGAAGMHLLALAWSCPECICYTLYTLAWSCPECICYTLYTLAWSCLECICYTCILCLELRNAFATPSISLAWSCRNAFATPCILWLGAAWNAFPTPLYSGLELPGMHLLHLLYSGLELPGMHLLHLVYSGLELPGMHLLHLLAWNICYTFYTLAWSCPECICYTLYTLAWSCPECICYTFILWLGAAGMHLLHLVYSGLELPGMHLLHLVYSGLELPGMHLLHLVYSGLELPGMHLLHLLYSGLELPGMHLLHLVYSGLELLHLLQYSGLELPGMHLLHLYTLAWSCPECICYTLYTLAWSCLECICYTFYTLAWSCLECICYTLYTLAWSCLECICYTLYSGLELPGMHLLHLLYSAWSCLECICYTFYTLAWSCWNAFATPCILWLGAAWNAFATPSILWLGAAWNAFATPCILWLGAAGMHLLHLVYSGLELQCICYTFYTLAWSCPECICYTFILWLGAAWNAFATPSILWLGAAWNAFATPSILWLGAAWNAFATPSILWLGAAWNAFATPLYSGLELPGMHLLHLWLGAARNAFATPSILWLGAAWNAFATPSILAWSCPECICYTFILWLGANAFATPCILWLGAAWNAFATPSILWLGAARNAFATPSILWLGAAAFATPSILWLGAAGMHLLHLLYSGLLAYFYTLAWSCLECICYTFYTLAWSCLECICYTLYTLAWSCLECICYTFYTLAWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHN7</accession>
    <name>A0A3R7PHN7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002196">
        <property type="protein sequence ID" value="ROT72165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHN7"/>
    <dbReference type="STRING" id="6689.A0A3R7PHN7"/>
    <dbReference type="OrthoDB" id="10044608at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="276" mass="30491" checksum="63E52D18405DB989" modified="2019-04-10" version="1">MPHCVGESETSGGDEWSSGDETDSSTTVSSTHQDPHCDCCYCHMLHHKQGGGRQKYSDRRERLLKILSRKKNARNNAVCPNTSSANAVTAASDSTEVPTSTGGTPLGGQNIDKIMDYIEGNQTDEAKRAKKAAKKARQRQKKLALKKEKKEEEKMKLEDKKGECEEEEEEEEEVEDGPLAELRRRAPDVTITVVRPGQQTSRTASSPQHSHLKNFHHSLNHPQELFSILPGILPKEGNHSLSLASILQRLPQASVIVNLLSVQWLVGVNKEALAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKK2</accession>
    <name>A0A3R7PKK2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_012228</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002552">
        <property type="protein sequence ID" value="ROT69567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKK2"/>
    <dbReference type="STRING" id="6689.A0A3R7PKK2"/>
    <dbReference type="OrthoDB" id="48057at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2720:FF:000001">
        <property type="entry name" value="Oxysterol-binding OBPalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF141">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="198"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="234"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT69567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="606" mass="65628" checksum="2E40357D616D087D" modified="2019-04-10" version="1">MVELQISRDKAGSIGIHVQLELLGQMSCPHTCTPIFCVLLSVSILSLKYVPPLSFLLFLNPLPVLGCLWCGGATAGVCPLLGSVCVDRVGSFGSLSGRCSPRCSPLLGRSPRFHRRTASDASSASLQRRRSSPTPTRLGSPSLRSSSPSLRIRTAPHSPTPGTTQGVSGTPPSSSAVQPLVPSSPAAVAASHCLPDVAGTTSSKSSSLASETPVSTPTPPPHSSRIGVTGYDSEVSDDDEAGGDGDLGEVGDGQRSVIMHIISQLRLGMDLTRVTLPTFILERRSLLEMFADFLGHPDYFAKIADATTPEDRMQAVVKWYLTSIHVGRNGSVAKKPYNPIIGETFHCNWRIPRDSIHGEVRDRGDWEWKATDGKKSPFVNIKYAAEQVSHHPPVSAFFFECPEKQLSINAHIWTKSKFMGMSVGVNLIGDITLIIGNVRESYSLAMPSAYARSILTDPWVELGGRVNISSPETGCQAAIVFHTKPFYGGRLHRVTAEVKNAAGTTLTKVQGEWDSQLEFTYANGSQEVVDVNDIPIVCHKRLKPLAQQSPMESRRLWHDVSVALARGDVETATSHKRALEEQQRKETRACCPKCAIPNTTIPFSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PL14</accession>
    <name>A0A3R7PL14_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Beta,beta-carotene 15,15'-monooxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006213</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001796">
        <property type="protein sequence ID" value="ROT75261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PL14"/>
    <dbReference type="STRING" id="6689.A0A3R7PL14"/>
    <dbReference type="OrthoDB" id="1069523at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042574">
        <property type="term" value="P:retinal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="51144" checksum="909D79CB5BB61ACC" modified="2019-04-10" version="1">MSKTAKSPPPPPSQVWLRSCEKETVEPIEGKLTGELPHWLNGRLTRNGPGRIEYGNTRINHLFDGTAYIHQFNIIDGKVTYQSRYLNSDTYKKNKKADRIVVAEFGTAAYPDPCKTLLQRFMSAFTPISKAEPTDNCVVNVCYFGDQLYALTETRNLRRIHPDTLDVVGDKTKLDNYVVVNTATAHPHVEPDGTIYNMGNAYAGKKGPTYNIIKFPPPKVVDGKKISSIQQAEIVSAIPCQWKMYPSYYHSFGITENYFIFVEQPYVFNLKKFLLNYYLGKPYFAAVEWYPDQKTKFRLVNRKTGEMVKTVYAADAFLTFHHTNAYEKDGQLVIDLASMKDGEAVNALMMKNLENPNFESEPATMPTHWRFVLPLDVQKAPENTNLITLEGSKCTAYKRADQSVEVHGHRISSQYFDLQRINYKYNGKEYEYAYGVEVNPKGSVFSQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNB3</accession>
    <name>A0A3R7PNB3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Caspase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001519">
        <property type="protein sequence ID" value="ROT77465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PNB3"/>
    <dbReference type="STRING" id="6689.A0A3R7PNB3"/>
    <dbReference type="OrthoDB" id="6355758at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043067">
        <property type="term" value="P:regulation of programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48169:SF1">
        <property type="entry name" value="ASTROCYTIC PHOSPHOPROTEIN PEA-15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48169">
        <property type="entry name" value="DED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Caspase family p20" evidence="4">
        <location>
            <begin position="245"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="467" mass="51819" checksum="228A5668610ECD5E" modified="2019-04-10" version="1">MSQSSSVPDQQQVSVAIAEERSSEGDRCSICGKRNCPADPKLRSKISQMPMPQKSLVGKPKSPRKSKFSQVNVMKGQLFKAVEDGDVVKVQELIQDTGAAVRKNKSRCTLLHTAASHNQADVVMFLLKLISPNITNEEGQTPAHVAAEKGHTQLGGHLFKAVLEGNKKEAERLLAVGADPDSHGGKLVNGVLARELGVTTAGLLASALNMEWAVTMFAKVPSRQFRVRHATAIQGADVYKMDKEARGFVRILNFSCFKDRSDLNLQQLDYDACIMSDVFDKMGYMCKTHSSLTAQQTKEVMKNIRDGDELTDVGCAIFVICGYSVNGRSVLTSDMKCVDIDYMLNAFKDSECPQLKNKPKLFIFNLFNMNEVIETSSSESPKVMRLTDPLNDMACLYSNSIGVNCVPNGKGTSFSWSLCRTLAEHAAEHELCDFYREFLKEYNKSSPSFSPELRYFGFTKKFFFNPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQL3</accession>
    <name>A0A3R7PQL3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001953">
        <property type="protein sequence ID" value="ROT74015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQL3"/>
    <dbReference type="OrthoDB" id="6376270at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="299" mass="32988" checksum="E82D4972CC6C6593" modified="2019-04-10" version="1">MTVFGAQALTSANVSRRRDIRGAPGKENAPCAGDHTPWQRLRVPVHHGGAPVATERRGQRGKQRMAQMYGGGYDDSEYESSDGFLPYVLPALAITGLSLLFPNIVTASATTPLCWSLLLLAVLAPAPVLGYSWGTYGSSSYESYDHDYYHPRSYQRQAEPRSIFARARSIMPRFADVAAETATSLAIPALVVLAFSALWPEHHYYRVKRDSGEMTTPTEELTEHMMNVYFAAMESDECLQRVVCELGASAKSLKPGNQNIIVSMLGSVSSKKYSSLFEKFKSGMNSERCQKIGCNFLDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSY8</accession>
    <name>A0A3R7PSY8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000927">
        <property type="protein sequence ID" value="ROT81729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSY8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="616" mass="66739" checksum="FE086D0EBEEED544" modified="2019-04-10" version="1">MKGPGSLLCRAQKYQKEVNSENCAALISSIDLNGAGIYSLFSFSYLQPLSSLFYTFLPSSPSPLSALISSFIPSSYFSFLFSLFFFFPIPFFFFSPFLFLIRISFASTPLLFSLFFFLNHSLLLSLFSFTLSPLLSLSPSLLPYLPFLPHPSSSLSLSLILPLLYVSPLLPLPLLPPLLLYSHPPSLLHPFSIIVYTYLFSSFLLPSLHSPFLHPLPTHLFLPLLLFFFPPSLSHPPTLITFTLSFSLFLLPSPPSLLSLFLLLSFPRPSSPLPLLSFSLPFLPYSFPHSLSPFVSPSHLISLHPLLSPFLLPSLLPSLLSFLSLLAPLLLPSLSRPPLPLTFLPPSQSLPFHLPPPLLSLSSSPLHPVPPSFLPFLSSILSSHSSPPISSSSPSFSFPLLFPFPALSTLMPSLPSLPSSPSLPFLLSPSFPFPSPPPPLPYFLLSLPFLPLTLLSFPLSFSPPLASFPPSTPSPSHPSSPPSLSPSSPFPPLPLTFLSLPSLLPPLTSSPFFPPSPLHPPLPFPLTLLSFFPPPLILSPFPLTPPSFPPSLSLSLLPLLSLSPSSSFPPSLSPPLPSLLLSPPSPLSPFPLTLLSLLPSLLPSPPPLSIGKSQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUI8</accession>
    <name>A0A3R7PUI8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-G-associated kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_003896</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001521">
        <property type="protein sequence ID" value="ROT77449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUI8"/>
    <dbReference type="STRING" id="6689.A0A3R7PUI8"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035612">
        <property type="term" value="F:AP-2 adaptor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045747">
        <property type="term" value="P:positive regulation of Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000369">
        <property type="term" value="P:regulation of clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000228">
        <property type="entry name" value="cyclin-G-associated kinase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1110:FF:000001">
        <property type="entry name" value="cyclin-G-associated kinase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000255">
        <property type="entry name" value="putative tyrosine-protein phosphatase auxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF105">
        <property type="entry name" value="CYCLIN-G-ASSOCIATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="35"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase tensin-type" evidence="5">
        <location>
            <begin position="429"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="6">
        <location>
            <begin position="602"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="332"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="773"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="832" mass="92784" checksum="6A504FE7A33F2007" modified="2019-04-10" version="1">MADLFKSAFGYLGSNGTTSDNDFVGQEVEINGIKLRIKKQIAEGGFAFVYVAQDLSNGKTYALKRLLGADQVACDAIRQEITISKQLSGHPHIVDFIAAAAIDKTQSKENRNEFLLLSELCTGGSLVDALRLLNGKQLSVPQVATIMYQTTRAVQHMQAQNPPITHRDLKVENLLISESGHIKLCDFGSAMTKIYEVDLGWSANQRGLLEEEMAQHTTPMYRAPEMLDTWSNYPINGQADVWALGCILYYLCYLKHPFEDSAKLRIINGNYAIPTNDGKYECFHELIRGTLKVDPSERFRVSDILERLAAIGETKGFSMKAPIQIECKKIDLTTPVHQPESNGRLGERRSGAPDRPPARPPAPRSPVPQRPPQPQRPPPPGSHPQHGVVGQSQQQTSAGGGGLFSSIKGYSGSIFKNIKDTSSKVMQTVSQSITRTDLDLSHITSRVIAMSYPAEGLESAYRNHVEDVKAVLDGRHMGHYVIYNVSGRQYHSTKFSARVVEGNWSGKKSSTLGALYNLACSIYDYLIKDPKNIVAVHCMDGKASTAMLVCSFLLVCHAFKRPEQALNMFAIKRSPPGLQPSQFRYLEYVRDLVASPAVIPHFKPVTITSVIVSPIPLFTQRRDGVRPYVEVWQGEHRMLSTLQEYDNMKLYMPQDNKIIIPINIHLVGDVCIYVYHARRMMGKVMGVKVAQLQFHTGFIPEEDTSIRYSLRELDDVCEPDRYPERFTVTVNIFVSDVDRAPPQPPPWVARPATSFKPNVAYSTAIEMEETRDKFASAHGSPATHRRDSLPKPGMISSEANKSDFMASLNWDKAQGGTQVREGLKIIRNWECS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVQ3</accession>
    <name>A0A3R7PVQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-2B adrenergic receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_021541</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004530">
        <property type="protein sequence ID" value="ROT60830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVQ3"/>
    <dbReference type="OrthoDB" id="5957871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF189">
        <property type="entry name" value="ALPHA2-ADRENERGIC-LIKE OCTOPAMINE RECEPTOR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="75"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="249"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT60830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="417" mass="45165" checksum="FACC92B02DC7D025" modified="2019-04-10" version="1">MIIYYRKISVPTSQPIKNTPTASTINPATNNSLLRQVSDDLGYVIYSALGSFYIPSCIMIFVYIRIYYAAKARARRGVPKKKPTPSGVGGGATRQVVGKPATKPPSNTSITPPIATATTTTSFSKPPPSPSNPAHGSEESSRNGTATERTSLLNKKVHICDVRVHEEEEAPPSRSATPTPNPEEETPLRTVSEQVDTDHRNHNAKSENGLYLGPLGSDNPPELTIGLPTPTAPPTPMREPNGGNMAVTVASPAGSLRRGVPTTSMEGDQMSDIDPSSSDSGVVTRCSVVKPLKLRFCHPLLGKKLTKPKRELIDMGRGACRREGPRPREGEEAAGAEEGEEGDADPGAHHGLVHRVLAALLHHVHHGAHLPVVLHPRVRLRPRLLARLHELGLQPHHLHHLQPRLQACIQKNYFQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVX0</accession>
    <name>A0A3R7PVX0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="7">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_002584</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the P4HA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01001345">
        <property type="protein sequence ID" value="ROT78710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVX0"/>
    <dbReference type="STRING" id="6689.A0A3R7PVX0"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000005">
        <property type="entry name" value="Nucleolar protein 5, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000001">
        <property type="entry name" value="Probable Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013547">
        <property type="entry name" value="P4H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08336">
        <property type="entry name" value="P4Ha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="17">
        <location>
            <begin position="283"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="18">
        <location>
            <begin position="904"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="479"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT78710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1003" mass="111690" checksum="5C823D5AA0F2047A" modified="2019-04-10" version="1">MLVLFETAAGFAVFKLLDEKKLKEVDNLFEDFETPEAASKVVQLQNFKKFEDSAEALQAGVALNEGKICKPLKKLLKKVFTDEVQEQLMVWDAKLGNTIKEKLGVQCISNNNVNELMRCIKSQVEGLIPGLQEKELSAMSLGLGHNLARYKLKFSPDKVDTMIVQAICLLDDIDKELNNYVMRAREWYGWHFPELGKILTDNQAYIRTVMAMGTREKAVATDFSDFLSEDLEEKVKEAAEVSMGTEVADDDMLNINSLCEQILELTEYRAQLFEYLKNRMAAIAPNLTILVGELVGARLISHAGSLINLAKHPASTIQILGAEKALFRALKTRNSTPKYGLLYHAQLVSQISAKNKGKMSRMLAAKAALACRYDALGEETTTEMGIENHSKLSSRMSMLETGYSRKLSGKAKSQSAFASYHGTSDVRQYHIAADTTMESSTKRKFDDSYGEQKAKRIKVEEVEEAAAITVSSYDSQREFTDASRSGKHALDSTARQSRSANREERIRTAKLRLNVVRCVRGTVCEMAAIKRTEMVFLVLFFTIAGVACDGHALHTSWAQIDQLWKDESEAIARIRTTMHSLSKLNEVLKRYVASWEDLTGSSDSGARSGDPAAAFALLHHVSRGWKHVDQVLQETKGVLGDIEHLASRPDRELLPNTDDLIGASESLARLAHVYRLNTTELARGGLHTTVDRERDSSYHTLSMSDLAHIGLVAINKGFLGVAVEFLRAARSKADVHARARARGSATLTPELSEVVVGTEFLKRHVNSTWMRNYRQLVELQQVERLCRGEDLRPVQVTSQLTCRYMAGNSAWLLLAPFKVEVLSLDPYITIVYEVMRPREAEEVKAKAGHLLQTPHNPAYGTSENGTQSGWTLKHTWLQDKDEPALQNVGFRLSQLIDVVVDDAASEPYMVANYGMGGTYEAHRDTHGPARRPHSEKAGERLATLLTYVEAPRAGGRTVFPWVGVGVTPAEGATVIWWNLLASHEHDFLTRHAACPVLRGHNVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZX4</accession>
    <name>A0A3R7PZX4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit protein uS10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000826">
        <property type="protein sequence ID" value="ROT82415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZX4"/>
    <dbReference type="STRING" id="6689.A0A3R7PZX4"/>
    <dbReference type="OrthoDB" id="5984298at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005761">
        <property type="term" value="C:mitochondrial ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027487">
        <property type="entry name" value="Ribosomal_mL48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13473:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13473">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="3">
        <location>
            <begin position="49"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="179" mass="20240" checksum="5DA671522C1704CC" modified="2019-04-10" version="1">MFSISKITARCLPVAQRALSTTASRCKISFEPPYLDAGGPDVPEFPLLNVQMEGYDFTVLEHYGKWVHRTALNMGIEVEDSWATPCEKIHIQTFKPRSVKVESEYDLHVYQRTVQLADVPSYLAPMFIEVAQAGLPEGVNLTVQEHMPEHTEVRFIPDLELKELKKQLDLLGGPSKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q864</accession>
    <name>A0A3R7Q864_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kelch domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010661</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002350">
        <property type="protein sequence ID" value="ROT71035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q864"/>
    <dbReference type="STRING" id="6689.A0A3R7Q864"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052637">
        <property type="entry name" value="KLHDC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46461">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46461:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="49120" checksum="035B0F6CC65D2FCF" modified="2019-04-10" version="1">MGPELPQESVRAGGGLWHLRHPRPQAPRPPPPPSWQGWTTTNLAIRESGGTSSRPGSMLWTVELEGGPQRVNHAAVAVGDRIYSFGGYCTGENYRTIRNMDVHVLNTVTYRWKAIDIKQEREFVPFQRYGHTAVAFGHLVYVWGGRNDVSACNILYCFDTNTHEWSVPKVHGHIPEARDGHSACIINDHMYIFSGYLEYVESYTQDVHTLNLRTMTWSYIKATGPAPVYRDFHTATGVDGIMYVWGGREVASGWYDSPEHEEYGADLYALDTVTNRWSIIPCSVVYRGQIYVFGGFNSRKCLHFNDLHRFDPVLHVWEEVKPLGQGPCPRRRQSCCVVGSKMFLFGGTSPKENYDEILEEDPNGEEQTDRRLKDHNDLHVLDFEPSLKTLCLLEVQKLKLDTTWLPRELHMLLNFMQMPNNITRPLNHTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QA59</accession>
    <name>A0A3R7QA59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004149">
        <property type="protein sequence ID" value="ROT61453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QA59"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003882">
        <property type="entry name" value="Pistil_extensin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01218">
        <property type="entry name" value="PSTLEXTENSIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="43092" checksum="BD03A27B455C9DC0" modified="2019-04-10" version="1">MHQWPRKGIEQQYGRRPPPHNNPTIPNTHQPPHPPSKPHNTTSSHPFPTHPPSAPPSPHPSSPLPLPSSSLLPLPSLPSPFLLAPPPSSSLAPTPFPFLFPPFLPSPLPLPSRPSPLPPSAPTPLPSSPLPFLLASPLPSFAPHTTPSPSPTPHHCPRPPHPPLASLLPRPNPTNFLSSPSPPSSFLAPPPFLSSPLPFFLALPPPFSLRLFFLAPSPSFSPLPFLPRPPPSAPSPFLPRLPPLPPPPPLPSSPLPSFLAFLPPPSFLARPPFLLAPPLPSLAPPPFPSPSPSFLAPSPFLPRPSFLLLAPPPPLLPRPSPSLPPPSPPPSLPRPSPLPPSSPPPPPSFSVPPPPPSPPLSFLLPSPFPLPSPSPSSFTSVVFRSGRNRAFILATGLFLAFLDLFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAC2</accession>
    <name>A0A3R7QAC2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004086">
        <property type="protein sequence ID" value="ROT61601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAC2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018711789" evidence="3">
        <location>
            <begin position="24"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="741" mass="80261" checksum="9DD89F72F8CDBACC" modified="2019-04-10" version="1">MRNFKFIRIGNLSIFQLSSLLLSLPLPHPPFSPPSPPSLPIPPSFSPPSPSLPIPSFSSHPLLLSPIPPSLPIPLLLSPSSFSLPIPPPSLPHPLLLSPNSPLPPHLPPSLPSLLLSPTTSFSPPNPPPSLPHPPSLPIPPSLPLLLLLSPPSSPFSPPSPPPSPSSPLLQTSSRLSFPYEQLLRINMNPDPYPPSLPRLCPYPPYAPPPLMPLPLMPLPPLCPIPHAPTPLCPCHAWPGNTTLAAGPLDYLLNIHRGNTMLKCLPLLSLSTSPLYLSLLSSPQSLSLLLSYLSISLSVSDPNSCPLSLSPSSPRSVSVLSLLSLHFPDFPSLSPPYASFFPIFLYFLIRFLFHPFYTNSPSLYLNLYIPSSLSLFLWFAAFLSLPSPSQKASNPLTRSLLPLSPSLSPCFFLSSLSFFLLSLSPRPLFPTLLLYPSSAPFSQPLSHGSPTLHIKSAPHHPHHHGIKYPFPQSQQNFGNPQKKKKTGDQKPGSNPSPQVAPAHSSWSTSFTALPKTNCRTRSLGTSLLALSRPTAGHTLSLPPGFCPANHHLELSILPPASALPLPPPDQTLLQTSFASGYTRGNRTLLSCHRFCPRYPPLTLSLPPTLPSRLLPRYRPHLLPTAFGRAIQPTELPHRCSPLATLSASACRHHRLDTLSTQPLLAWRSSAPCRSPTDTSCSLPTQRLLPATTDADTALSADPLLPAAHLTDTLSLTTRPRSWPPLPDLDHRYPPLLPYPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QC31</accession>
    <name>A0A3R7QC31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003508">
        <property type="protein sequence ID" value="ROT62996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QC31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="51730" checksum="133D8447D3FFB4A2" modified="2019-04-10" version="1">MLLVCVVCGACYAAGLVCLAMLLVCYAAGLVCGACYAAGLCGLWCLLCCWSVVLAMLLSGVCGACYAAVLVACAAGLGACYAAAGLCLVCVCCGACYAAGLLGGLAMLLSWCLLCCYAVLLLVCGCLLCCRACYAVVCGACYVLVCLLCCWSVVACYAAGVVLAMLLVCGACLLGLAMLWSVVLAMLLVCVLAMLGLWACYAAGLWCLLCCCLWCLLCCCWCLWCLLCCWSVVCGAWMVCGLCYAAAGLWCLLCCWSVVLAMLLVCGACYAVVCGAAMLLVCGACYAGLWCLLCCCCWSVVLAMLLVLVWCLLCCWSACGACYAMCWSVVLAMLLVCGACYAAGLWCLLCCCVCWCLLCCWSVVLAMLLWCLLCCWSVVLAMLLCSGCCYAGLWCLLFLVCGACYAAGVVLVIAAGLWCCYACVCGACYAVVCGACYAAGLWWLVVLLLWYGLVWWSVVLAMLLVCWSVVLAMLLGLLVLAMLLGLWCLLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QD67</accession>
    <name>A0A3R7QD67_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006476</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT74992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QD67"/>
    <dbReference type="OrthoDB" id="6360984at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="42400" checksum="072C59575F749957" modified="2019-04-10" version="1">MATGIGSAVLGALKAVSVEPVMLVDGACNQAMLLFIENVQMNKICSINLGLPDQVCNNLSEHPEEDVLVQREFSVFAFYNSIIMSIIPLIFVLFMGAWSDKYGRKIPLLMTLIGHVMYAGGYLLSNWQTSWPVEVIYFVTVLEALGAATTANSLWYLGGPVGTLVGALVIKYGGYNLALLLVLLAYLSAVLYVVFVIKESHGPFAKTALQAHGSAKQEPSPDSKEVSKLRMASDFFNWRRVVESFKTAFRQREGNARKFIMAIILSNMLRRVARGFFMYMFVRRALSWEATDYGYWVTYRNLLAAIGSLFLVPILTKMLSFTDASLAVLGSLSIMGEYVCYSLVNGVSQAFLMWLGPPVGVISNAASSPSDLCPPNLSAKRRKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE82</accession>
    <name>A0A3R7QE82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mannose-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005494</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001710">
        <property type="protein sequence ID" value="ROT75937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE82"/>
    <dbReference type="OrthoDB" id="6375279at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407:SF1">
        <property type="entry name" value="RE43931P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407">
        <property type="entry name" value="RE43931P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018686245" evidence="2">
        <location>
            <begin position="16"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="24"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="18162" checksum="62996E3D8B7D58B6" modified="2019-04-10" version="1">MKVLLFLTVVAVALGDDDVVDEDRGDSEYHFAWLHDGGRTYDWQGANSYCSSLGRGWKGISIETREENDFVTDVIEHHELPWVWTGGQRRGRDFVWPSGARFVGLNWSHTGGKKQPQPDNREQGGENCVAVLNDFYDDGVRWHDIACHHEKSIICERDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFF7</accession>
    <name>A0A3R7QFF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative thioredoxin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003039">
        <property type="protein sequence ID" value="ROT65772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFF7"/>
    <dbReference type="STRING" id="6689.A0A3R7QFF7"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="19143" checksum="A50E5790DAE82647" modified="2019-04-10" version="1">MEDSGVPGHIDLLPMVNKAGCECLNESDDHPFTQALNSAGGYLESDTDEQLILYLSFNQAVKLHSMRIKAPADCGPKTIKVFINQPHTIDFDTAESANPIQEITLSPKDLEGELITLKYVKLQNVMNFTIFIKDNQTEAETTQISYLQIIGSPVQTTKMADFKRVAGKKGESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QU75</accession>
    <name>A0A3R7QU75_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_002749</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001367">
        <property type="protein sequence ID" value="ROT78544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QU75"/>
    <dbReference type="OrthoDB" id="6375148at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="648"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="486"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="230"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="681"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="294"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="681"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT78544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="733" mass="80389" checksum="65FAE11081BA588E" modified="2019-04-10" version="1">MIDWKMFPMKLHYILRYAGTGPLMPFLPVIARQKGVSDHVVGIIWTVMPFFRSYPFVGPIPSSGRLSFVVLSFQVLSLLQRSIFRSYPFVGLSLRQVGPIPSSDSPIGRSYPLLSLRQVGPIRCYPSSGRSYPSSLSLLHVGPIPRCYPFVRCYQVGPILLQGPIPSSGRSYPSPKVLSLRQIVSFVGPPFHQVLVDLLQVGAIPSSGRSYPFVRLAFALLQSAGEDDGGGAGRLLQGPPRCLPRESGRHDGGADGDLLTLDRQRHLDNRGTLDPNPPGTTLRDTGSPKPPGTTLETLDPNATWNNLRDTSTTLDSPEGHSTPNATWNNPGRHSIANTTRDNPATSGERPPSWDVVRDTDVEGTSVGVCGGNESECLGDSLMRVELPASELATRYEFWILFLWLLLQFCGYVVVLDLQEAVCFQMLGDAPHRYGQQRLWGTISYGLAAVAGGALVDWYSKDQAQKDYWPVHKLSRADVHEVFRRPSVMLTVLTTVVLGLSCGMIGTFHFLLVEDVAAAWDPEFLHLKLLQGLMLGVQCLVAEVPCLFLTGWLIEKIGYVNAFLLSLSTFCLRLCLYAAVTNPWWFLPIELLHGVSYAVAFAGVASYANSVTPEGAEATMQAIFGGVFFGGMGVGGLVGGWLFHLVGGWKAFLFVGVGNGVYAILYLAAHLALERLCPAHSPSERGKNYDEVRNTEEPATRYSECSNRDRQDNSEDSEREAIKQRKITNNVTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWZ7</accession>
    <name>A0A3R7QWZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000998">
        <property type="protein sequence ID" value="ROT81254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWZ7"/>
    <dbReference type="OrthoDB" id="6329352at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="206" mass="22628" checksum="8B19BCDBC8CA0977" modified="2019-04-10" version="1">MDRGGGGPQRATLQASAAAPPSVPRLPRSRSVLRPWCPYVRPYVPPRTSDPPHCSAMRTRIWLTATLLALAMEVVWGDPLGGGSSGRNPAKPRASAQIYPLADREGNSLYALPPKLTGEMIQSLARTRHWRPYQAIGTSYDVARKPGQSSHRGRRDATSSPCTDGKVFRRGVCQCPYLSEWDEEQGACACTYGTYRDSRGNCHPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SN28</accession>
    <name>A0A3R7SN28_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002733">
        <property type="protein sequence ID" value="ROT67986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SN28"/>
    <dbReference type="STRING" id="6689.A0A3R7SN28"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="46846" checksum="6D93C4E5470EC630" modified="2019-04-10" version="1">MDLHAYVLSLYLLSPSSLPLPTSSPSLLLYTFLFPPHTNDCSPYLSLFHHSLTFPPPHIYLLSSLSYPSHTIHALLSFSCPHIYLPLSASAFPSRICNLPPAFLLRSLRPHSARPLIPCSVTVRVPKQCLPHLTSSLPSPSPIWALLPPPFPPTIYLALSLSSPPHICCSLLSPPNLPLPVIPSSFYLPHIYLLSPSISLRLTPPSLPSPFPSHTACSLRLFPTTICLLSPAPSPLPLTSTLHSLHSSSSSYRPSPSLPSIYLLSLSFHSHIHLPPLSLSFLPICLLPPFAPPTDLPLLLPLLHRRHSVYLHTLPLTSLRRHHTSLFPSPPPTSYPSSSLRYRIGSYPSSRCSPHLPSSLISLLLPLTPDDLLSLSPSLTPNLLLSAPLLPAPQDHGSNISFCLPPLLAQLFTSRHIASLNLLLLSSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVX3</accession>
    <name>A0A3R7SVX3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="13">HMG-CoA reductase</shortName>
            <ecNumber evidence="13">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_003389</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:15991"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01001458">
        <property type="protein sequence ID" value="ROT77909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVX3"/>
    <dbReference type="STRING" id="6689.A0A3R7SVX3"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.770.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004816">
        <property type="entry name" value="HMG_CoA_Rdtase_metazoan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00920">
        <property type="entry name" value="2A060605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0521">NADP</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="15">
        <location>
            <begin position="85"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="794"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT77909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="838" mass="90555" checksum="A4E1E3160865AAF0" modified="2019-04-10" version="1" fragment="single">GGVAWRAFWSHGRLCAARPWEVIFSVITTTVAMISLADLYKAPRQPRTPQEYQGLDVVVMTILRCSALLYTYHQFRTLHRIGSKDALFFFLLLVDLSKASLLAQFALSSSNQIEVHTNIACGMARLGPSLTLDTIVEALVIGAGTLSGVSRLEQMCAFACLSIIVNYVVFMTFFPACLSLVLELSNRCSSGQPPWQMATLARAMVEEEKPNPVVQRVKVIMSAGLLLVHGITRWSLSLTDSSSSTQDVPQSFNSSTDPHIIVRLLNAGLDHIVFMVMLVALIIKYVLFESQGQLEENLIHDSLITPQDTLDNSRINNKGGLNTSGILRQRTRSRTTSCNSQWEEIPPKKIDCSSQTDKEAMSLRGYCLEKEDEKPPRSIDECLLIMSSEAGVKSLTDQEIVQMVEKKHVPGYKLETVLGDPLRAVAIRRSVIAPHTASQNALETLPFDHYDYTKVMGVCCENVIGYVPVPVGVAGPLLVNGKKYMIPMATTEGCLVASTNRGCRALVGGVKSEVIRDGMTRAPSVRMPTAAQATQVYKWIRKKENFAIIKEGFDSTSRFARLQDLHVGLAGRLLYMRFVAQTGDAMGMNMVSKGTEAGLKALKIHFPELEVLSVSGNYCVDKKPSAINWIEGRGKSVVCEAVVPGKVVTSVLKTTVAALVEANVTKNLIGSSLAGSIGGNNAHAANIVAAVYIACGQDPAQVVGSSNCMTLMESWGEYNEDLHITVTMPSLEVGTVGGGTGLHPQSACLNMLGVKGAHKDTPGENSCQFAKILGATVLAGELSLIGTKVVEETKAGTEAAPSAESSRSQDGEKENGITGSFQACKDPADLSVPHSRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYQ3</accession>
    <name>A0A3R7SYQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000892">
        <property type="protein sequence ID" value="ROT82052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYQ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="43950" checksum="30019EA0335AB7B6" modified="2019-04-10" version="1">MERYTWRRLPGVDLKRGQLIRQSVFPDASPGWSSGGMSCGLPPCSYTPSKTRPLHPTPSAEDTHPGRLEDSLPPVALKTPPPASPRRLPLSPSKTPHPPSPEDSPPGRPRRSPCRFSKTPRLPLSPSKTPVASRSPPPVALEDPPLSPSKTPLPRRPPPTGRPRRLPRSPSLRPHHPEAFSPAAASLHPSPPPHPRFPVSTPPPKPVKSPVGFLNRLLQGNDGPSSRPLAVPRAGHWRSSSRPLAVPRAFEQQVLEQALAVLEQALVLEQATWRSLEQAHLGSLSRLLAVPRARSSSRPTWRSSSRPLGGPSSRSSSRPLAVPRAGQVPRAGLLGGPSSRPTWRSLEQAYLAVPRAGLLGGPSSRPTWRSLEQAHLAVLGLWRSLEQALRAVLEQAHLGHRRKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9K7</accession>
    <name>A0A423S9K7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004499">
        <property type="protein sequence ID" value="ROT60889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9K7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="727"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="836"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="206"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
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            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
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            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
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            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
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            <end position="338"/>
        </location>
    </feature>
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        <location>
            <begin position="348"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="423"/>
            <end position="455"/>
        </location>
    </feature>
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        <location>
            <begin position="456"/>
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        </location>
    </feature>
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        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
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        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
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        <location>
            <begin position="543"/>
            <end position="554"/>
        </location>
    </feature>
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        <location>
            <begin position="555"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="583"/>
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        </location>
    </feature>
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        <location>
            <begin position="597"/>
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        </location>
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        <location>
            <begin position="610"/>
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        </location>
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        <location>
            <begin position="727"/>
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        <location>
            <begin position="836"/>
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        </location>
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    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="916" mass="105070" checksum="9C2FB29DF46D03A4" modified="2019-05-08" version="1">MQTRCAIIDRHYNGNPYRSRRVLTGFYNGCVARVKGEPVCARWAEWLFPLCSHPTLPSSHQLPQHPHTHTTPHPHTHHTHANLHTFDAHDDRIHTPHTHTLPTPQHTHTPRSHTHTTPHTAPSPHTHPPLLYSTLSSLHTQSHPTHHTHTAHTHTQPTHTHTSPHTHTQPHTHTTPHNTPHTHTQHTHTTTHTHPTHHYTPNTTHHFPHHTHHTHTHTTHHEHTTHHTHTHTHTHTAHPTQHTPHTHHTHTPHTHTHPYTTHTPTHTPHTHTPHTHTHTHTHHTTHHTHTQATPTHSILHHTTTTHTPHPHHPTPPPHTHHHTHTTPQHTPPHTTHTPHTPPPPYTHTHTHTHIHTATHTHTPHIITPPPHTTSPHPPPHTHTPTHTTPQHTDHTTPHLTPPPPTTPHTPHPTHTPTPLTHTTHTHHTHPPHHTRHTTTHTHTHTHAPHSKHTRTHTNPAHNTHTPPHTHTHNTSPTHTHHPHTHHTPHHHPHHTHHHNPTYTHTPHTHTHTHPTPPHTTPTRTPTTPPTPPPPTTNPPPPTHTTLYTTPLHTTPHTHTHPPHTHHTHPHNHTPPPHNTPPHTRPHHTHPHTHPTYNTPPPHTPPPPPHPHIHHNTHTPHHTHTHTHTPHTHHTHHTHLHTPHPHHHTPTHTPTHTHHSTTHTHTHTPHSHTPTHHTQHTQQHHITQHTTPHTHHTPPPHTHLHTTHPHTRHMHTTHIALFTTHTHMQHHTPTCTPHTTSCSPQPHAHATPRPHAHTQHATYAHQHITQCTTTTHFAHQHTRTCHHTHRTHALHTIPLMHTTHTHMHTTHYHWQPTHSTPRTPTLCHCHHAPALPKPRHAHAHPHTHMHHHFRPHAHHAHSTLHTTAHASSHHAHAHAHHAHAHATHAHAQHTTRRPHHPPHTPEHAHHTFRHAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9M4</accession>
    <name>A0A423S9M4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Suppressor of cytokine signaling-2 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_021489</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004511">
        <property type="protein sequence ID" value="ROT60867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9M4"/>
    <dbReference type="STRING" id="6689.A0A423S9M4"/>
    <dbReference type="OrthoDB" id="10063348at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005942">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046935">
        <property type="term" value="F:1-phosphatidylinositol-3-kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09923">
        <property type="entry name" value="SH2_SOCS_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001496">
        <property type="entry name" value="SOCS_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036036">
        <property type="entry name" value="SOCS_box-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10155">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10155:SF16">
        <property type="entry name" value="SUPPRESSOR OF CYTOKINE SIGNALING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07525">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00969">
        <property type="entry name" value="SOCS_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158235">
        <property type="entry name" value="SOCS box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50225">
        <property type="entry name" value="SOCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0341">Growth regulation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="2" id="KW-0734">Signal transduction inhibitor</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SH2" evidence="7">
        <location>
            <begin position="117"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="SOCS box" evidence="8">
        <location>
            <begin position="222"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT60867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="270" mass="29453" checksum="0522557D42C97617" modified="2019-05-08" version="1">MLTCPNCHHVLAAHSCCGLNLTVPSAAFPPSATSGASVPSAAMLGPRLGPPGGRAALAQRQRPPAAAGARHAAHQRPHWPDSGGSLPGPAMAARMHTSGGGIRVLGATRRMLGESGWYWERLSWRQAETLLQSTSLGTFIVRDSADTRFLYSLSVQTERGPTSVRIHYASGKFRLDCESHMAATIPDFSNVIALVEHYIRVNQKLQKHFWVDAQGKVYCPITIRQPLKRAVPSLKHLCRLAINLAVPRSCSALRLPPSLCQYVDEYPYWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9R2</accession>
    <name>A0A423S9R2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-2-macroglobulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_021346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004468">
        <property type="protein sequence ID" value="ROT60960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9R2"/>
    <dbReference type="STRING" id="6689.A0A423S9R2"/>
    <dbReference type="OrthoDB" id="6376547at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041555">
        <property type="entry name" value="MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040839">
        <property type="entry name" value="MG4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF171">
        <property type="entry name" value="PREGNANCY ZONE PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17791">
        <property type="entry name" value="MG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17789">
        <property type="entry name" value="MG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macroglobulin" evidence="1">
        <location>
            <begin position="58"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Macroglobulin" evidence="3">
        <location>
            <begin position="148"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Macroglobulin" evidence="2">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT60960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="470" mass="51511" checksum="B1C1DF0B1AB4F66C" modified="2019-05-08" version="1">MSALSIPFLLPGRVETCFEVTLPQADHFDAKLSVRGRAGGADFEDTRDIRLQKSRNLTFVQTDKYLYQPGQEVKFRVLTIRGWRATYPEIWVTTPSDTRIAQWIDAASTSGLLHLAFQLADEPEEGLYTIHVRGPGDGKKTRSFKVEEFVLPRFEVKVTPPQFALATDRVFTFNVCANYTFGQPLKGTVTLTVSNNQRRKCRINIKRTEPITGCKDISVTSKELRITDCHVFRLSATAVVEEDGTGVRLNHTASASVSRSAVNFVTVYEDNYKKPNLPFTLKVKATLPDDSPAVGVPVEVCAAGMCTNRTTQEDGVFTVVVASDDASRVFMSTLNCRADLSASTFSKDIRQYFSPSNSSLLLQVPEKKLKCEAGLSGNYNLPVWFSANNQPRASLTVQVVSRGKIQHLSTRQVSFAPSVFPIDTEHLVDTPTNPGFPIVMGVLNLPISLPPTASPTAQVGVVEGGGVGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCN9</accession>
    <name>A0A423SCN9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative leucine-rich transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020253</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003917">
        <property type="protein sequence ID" value="ROT61925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCN9"/>
    <dbReference type="STRING" id="6689.A0A423SCN9"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050333">
        <property type="entry name" value="SLRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45712">
        <property type="entry name" value="AGAP008170-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45712:SF22">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Ig-like" evidence="6">
        <location>
            <begin position="443"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="672" mass="75202" checksum="3E0ED15E57AAF80F" modified="2019-05-08" version="1">MVTKRKFGVNLCSGLPLPVVVAVWAASFVGVALGNARSTSSNDVYNSTCLEGCTCGKLRSNHLHEELDTFDCSFNNMYAFPENLPQDLQVLSLRGNSIFSVLDNICKLTDLRELDLSGNRIKSIGRGRMFQNMTRLEYLSVGKNSISTIFHDNLMGLKSLVHLILSNNKINYIEDKAFIELSHLLTLDLEQNLLGSLYAEWFQGLGGLVALNLAHNRIHKIPASLFRDLVSLERLYLAGNRISAVDPRAFSGLMNLQHLTMENNLLSRIPTAAYQSLPSLLTLSLDQNPLVKIKPLDFSHLSVTKISLCQMPELEIIDSKGFYNLANISTIEITDNAKLAYVDPLAFMNVDTLRDLHLHNNNLRGLQKEMAAYLPEGVQVSLYENPLHCDCNMRWIQKLIRKGENASIVIMEPEHLVCHSPTSLAHKLLMNLVPTKLPKECLPMVLNLTQSQTVVGKVGERQVLECRALGSPRPQLRWILPDGSLVNSTLNEVRRRFFPPGTLVYYHLKPRDGGTYTCVAENSVGETRSSLTLNVTGIDIHLFPIRMSSTLVTLVWNGTERRAFPSYKIVFSQIDANGTDVGEKRSSTASPTRKTFTITGLHPASTYRFCIGYEDASGYWLQISCCVANTRGVEFMMQGKYRHRMYETPDKVGEDSNSVPLDNLYRPLLMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDI3</accession>
    <name>A0A423SDI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Thrombospondin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_019899</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thrombospondin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003745">
        <property type="protein sequence ID" value="ROT62259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDI3"/>
    <dbReference type="OrthoDB" id="6357843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000002">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017897">
        <property type="entry name" value="Thrombospondin_3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008859">
        <property type="entry name" value="Thrombospondin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05735">
        <property type="entry name" value="TSP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51234">
        <property type="entry name" value="TSP3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51236">
        <property type="entry name" value="TSP_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 9" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018994637" evidence="12">
        <location>
            <begin position="20"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="32"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="10">
        <location>
            <begin position="122"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="10">
        <location>
            <begin position="181"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="10">
        <location>
            <begin position="274"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="TSP C-terminal" evidence="14">
        <location>
            <begin position="313"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="236"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT62259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="537" mass="57540" checksum="CE276D1789440523" modified="2019-05-08" version="1">MWTSVWLLTVAATQMPGAAILQAAVTVLVNQDVDECLVANGGCHAKAKCTNTAGSRTCSCLAGYTGNGQVCVVLKCPVGFAGEGADCAPDSDLDGYPDTELSCSSKYCRKDNCINRPNSGQEDADGDKIGDACDADADGDGHNNNKDNCPLVANSGQSDKDNDKRGNLCDNCPDASNPSQSDIDGDGIGDKCDDDIDNDGLLNAADNCPKVANGNQADGDGDGIGDACDNCPKHPNAGQKDKDEDLLGNACDDDVDTDSDGVEDSVDNCPNNQKDTDGDGRGDACSNDLDGDKILDSDDNCIANPSVHSTDFRHLQMVALDPQTASTPPVWVVYDNGAEIHQTVNSDPAIAVGDHVMGDVDFEGTFFVEDTSDDDFVGFIFGYQSNAKFYVVSWKKGPQNWFNKAERGVTLKLVNSNTGPGTKLRDALWFTGSTANQAKMLWHDGSIGWKPKVAYRWLLHHRPDIGAMRFYLYQGTKQVMDSGNIYDGTLKGGRLGLYCFSQEEIIWSNMEYKCANGVPQEMFNDLPANLQNQVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDS7</accession>
    <name>A0A423SDS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003722">
        <property type="protein sequence ID" value="ROT62349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDS7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="431" mass="46640" checksum="ECF88472ABB04675" modified="2019-05-08" version="1">MTGNALPSLSLSPLPLPLFFLSPPFPVTFLPCPPPSDLFHPLLPLYSFLHPPLPHLSLCFSPSLHFFLSYPSLSLSSTHPLFPSILPIIPHTHLLPPSVLLSSIRSPFFIRSPSLPFLSLFLLPPLYPTPPPLPSPLLPYSSFPLYLPPFPDPSSSSRHHSTSPAFSPLLLFFTYPLPTISSSSPLPIMILLQPFPYHPSLPSLPSPSFHHFFLLRPPPTISFRTTPPTPLFTPSRLPSSPPLPPSSPLTHPPPPSLPLLPIPTPPTPPYPLLLPSSLPPTLLFTPSPTLLFTLLSFPLPSLFPFPFTPPPPLPPLLFTPSPPPLSSLPLLFTLTSSSLPPPPTPSSLPLLFTHPSSLPSPTPSSLPLLRPSLTPSTPSSSLPPPPTPSLYPLPTPPPLPTPSYPSPLYPLPHPLLFTPPLKRLVSLYKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEA6</accession>
    <name>A0A423SEA6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Period circadian protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_019628</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003648">
        <property type="protein sequence ID" value="ROT62526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEA6"/>
    <dbReference type="STRING" id="6689.A0A423SEA6"/>
    <dbReference type="OrthoDB" id="7788983at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001222">
        <property type="term" value="F:transcription corepressor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022728">
        <property type="entry name" value="Period_circadian-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050760">
        <property type="entry name" value="Period_circadian_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11269">
        <property type="entry name" value="PERIOD CIRCADIAN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11269:SF16">
        <property type="entry name" value="PERIOD CIRCADIAN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12114">
        <property type="entry name" value="Period_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019382425" description="Period circadian protein" evidence="7">
        <location>
            <begin position="25"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Period circadian-like C-terminal" evidence="8">
        <location>
            <begin position="393"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="367"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="533"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="329"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="379"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="414"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT62526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="601" mass="65639" checksum="C043BB2DEE3DACD7" modified="2019-05-08" version="1">MRRTLIKHPSAFLICCCHFHHLLAAVFPCCAKFRKSESTGNGSGSGDNGSYRHVQLTEEVLSRHNADMQKMFLQRQRTGGKLYKDKWKIKSMKKLMKKSGDRNHGIKRSGAVLEQEASVQKQPYLAPPSGVPGPLKPPPREGWSQNESKASETPGQSSTTNVGPNVLPTGRLAAPPFPGIMPGYYLPTSTSSVSPIPPMENLLVPQPPGPTLLMPPQQPTYIQPQASMAVPVQYVGAFPGVMYQPVGPPLFNAPPLMLPNVVFQHTVVQSPHGQISIPLSSDGEKRSGAESEQEMDPNQPSGKNFTLKRSAVHMRRPDSQATSVKAEPGSARGSTASASGKIISSHSHAAESIRSFVEDTTILSPGCAPKLDREKNHDSSQFSQSTSVRAEAESVGSPGKQDKAALDDREQCLDNNSSDMITSSTNSSREYKSTDDSVQNISEQSENSEASPAAIKWNLPRSKCRRPILNDPPWLDDVKVTPELLYRYQLETKELVDVLRHDMDMLKKLRQPVWVDDQLSSLYHELELEGSSPDLHLEEGVTSSSGEDQAGTSSQNFARKKKSSMYFSKMSMLHEEDAPMPPPDVGLLTGHPAPESSTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIN0</accession>
    <name>A0A423SIN0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integrator complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003329">
        <property type="protein sequence ID" value="ROT64086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIN0"/>
    <dbReference type="STRING" id="6689.A0A423SIN0"/>
    <dbReference type="OrthoDB" id="69088at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040316">
        <property type="entry name" value="INTS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029444">
        <property type="entry name" value="INTS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029445">
        <property type="entry name" value="INTS5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31697">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31697:SF2">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14838">
        <property type="entry name" value="INTS5_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14837">
        <property type="entry name" value="INTS5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrator complex subunit 5 N-terminal" evidence="1">
        <location>
            <begin position="56"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 5 C-terminal" evidence="2">
        <location>
            <begin position="250"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 5 C-terminal" evidence="2">
        <location>
            <begin position="529"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="68179" checksum="1A56E751DD555104" modified="2019-05-08" version="1">MVVTGVMEPGATTNVDGGGHTISSTMLLAELDRFLSLALTTTDKRSHSGRRDGISEGEEQTMAETALFLLRNLPPARPAALAFLAHTLSKQVSSHMRGFTSGDSTRKTDAGDDGLSGQLEGLLGELVEATPGVWGPLVSQWAVEQLGRWSVEWANTVVGRGDATLEEVVAGWLSCGPARTLAALTVACVAHDPDTAVAALLDASAASGPALDWLVAHVGCSFPARVISRVLALGLCSFASCHGRPPEHQLASVNKILSHLADRHLPDIRRGLHAILTRTFNGTTDEEVQASVPFLLCLAVTSRSRAVLAALTSGLDTLLMPGDRLGALAKQVGWWVPRYFNTHSQLQEMVVHLILDTGGAAAPSLLRLLLQGAASTPKLPPTVTAAVNSVLQGVVGEICIVTYMRRNSGSGRIHIPFLVGLRGGGLDGSDVGIAVGGRAVSPVAGLVEETLALPGTEANLIIRLLVEGVFRPECAHLFGALSHAKLEIKEVTGEKLINANRQFDTWVKAPQSHTTALTAFWNTFPLAAAKQAPEALQATRNLLEVMVTAQFLPGPLKVLPQMVEALAPYEVVCILQDVWMYMRDHTPSPDRWRELPSGYQRIPEPPMAPVYTERIKRIIQCNVDTIGHLMCAMVNADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN79</accession>
    <name>A0A423SN79_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative gamma-interferon-inducible lysosomal thiol reductase-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016412</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003066">
        <property type="protein sequence ID" value="ROT65609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN79"/>
    <dbReference type="OrthoDB" id="958254at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF8">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="244" mass="26827" checksum="36E4C37CA871C25E" modified="2019-05-08" version="1">MSRVRRRAQRQCRLDAHCPSDSVCCADGCGHHGKICKKKARNSNALAYRPSKVNMTVIMTSASAESQQFLTSYLAPLELSLRNYVRVEVVPFGRVENGGCQHGPGDCLGNRLISCSERHLAAADRGVAFAVCLTKYQHQLRSADHSAILSAALSCAEGSRRNTKAFYRCAVGPEGYQLFAAAGRRQYQLVPFLSYVPTVLIDGEVVVRSYGDMAKFPSALCSKLDHLPQVRSYCQSLGHQQVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN98</accession>
    <name>A0A423SN98_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003052">
        <property type="protein sequence ID" value="ROT65715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN98"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="761"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1086" mass="118357" checksum="A1B293EC4A76127B" modified="2019-05-08" version="1">MILRRIFSVFVSSLLLSLFSFQPFVMTSLALPRPRSTFSFPRSLSAFLDLFRPSSPFRYLFRPFFYLFRPFSTFFPFTLGFPRPLSAFFYLFYSLLTCPRPFFPSSTSFSFLARLRPLSPFLDLFRPPSPAFDLLPSSPSSILPSSPSSIFSFSVFVLILLPLPFSFSFSPNLSRPHSPFLVLFLPSSPVFVLSPFSTSFASLACLRPSPFLSVFDLSPFLAVFVLISLPLVFVLFLPSSSFSSPFSFLFSLPRPSSSSFSLSRRLSSSAAFDLLLPLPSSLLLPLRLRSSLPRPSSSSFSLPLPSSFSFPSSTSFALPSPFLVLFLPFLAVFILFSPFLDLLPSFSLPRPLSPSRPSSSSFLPFPRPFRPSRPLSPSFSLPDLFRPSSPVFRLLLPSSSSFSLPRPSSSSFSLPRPLSPFPRLLPRPPPPSRSTSTSSPSRSTSTPAVSGAWAETRRLRPFHEAKFETSDDDVKWSGRIKMAGRRADAAVGVGGVGGRAHSHPRPHSRRHKVDVVADPGPQWAGGGAGACEECLSRRGPPGGYWRVFERPLQQVAAALDRLDQPLAPPALRAHLLGTRTLLRHLASALHLPVMDAVKGEDPEQPETQAAVLAAPGKTKGRLACPEWFMGSRVGYPRYTRGFAPLNCSAVPFRQVLTAVLWDLDQKDLMALQVEFSRLYPGLPLTLVTEGAAQSQPNVVLERPKPTVAAALSRALSRVTTPYVLLAPRLAQLSQSRRRPAGLHEGLRGLPARVPAVPLAGGAAGDEGGGAGEPRLAPRDLADADADAGALPGHPGGARPAHKHAAALCPDAMFLLRSLEPPWEVTPQPRHHDREMRRLAALWQPLVKRRRLARLHLPSGLTINYPCHFLPAARPAHATHLSPTPVDKAVSAAWACESKEVSTMLTALLRACDNLQVKCHLLDPVLSGMLGGQSLQEEATKVLSLGVEDPQAIPQMPQNANISQFPASFEDGVLRVEGRWWAVTMAPTTSSQDAHWTRMEVLEGVWAWAALPSSEKWAAEGRREGAPDVQIFDSSRADELALFMSPRCAQGRARARPCAGGPTAGAPECCLPGALAEGRSRHGMVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNK8</accession>
    <name>A0A423SNK8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative proline-rich extensin-like protein EPR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003050">
        <property type="protein sequence ID" value="ROT65724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNK8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="898" mass="102856" checksum="186DF50ACFBD0BA4" modified="2019-05-08" version="1">MHIPRHPHSPLSPYPHSVIHNFRYHIPRHATFPVYPHFHPIPVSTSPLYSPSSTFPVIHIPRYPHSRLSTFPPSSHSPSSTFPSSTFPYPHFPLSTFPFHIPRYHISPLSTFPVIHIPRYPHSPSSHSVSHFPLSTFPVIHIPRHPHFPFPHPRDPTFPVIHIPYHISPSSTFPVSTFPVIPHSPSSRIPRHPSPPHITRFPVIPFPVIHIPPSTFPVIHIIIPRHPHSPSSTFPVIHIPRHPHFPLSTFPVIHIPRSSHSHYPHFPVIHIPRYHIPVIHIPRYPHYPHSPHSTFPVIHIPRHPHSPVPISPLSTFPVITFPLSTSRYPHSPLSTFPVIHIPVPLSTFPVIRIPRHPHSPLSTFPVIHIPRYPHFPVTTFPVIPFPVSFPVIHIPRSSTFPMYPHIQHSRYPHPRYPHSPSSTFPVITFPVHYPHSPLSTFPVIHIPRYPHSPSSTFPVIRQSTFPVIHIPVIHISRYPHSPFVPHSPSSTFPSTFPVHPHSPSRYPHSPFHPHYPHFPSSTFPHYPHSPSSHFPLSTFPVIHVFTRHPHSPSFHPHSPSSTLSTIHIPRYPHFPLSTFPVIHIPRHPHSPSSTFPVIHISHYPHSPLSTFPVIHISPSSTFPVIHIPLIHIPVQSTFPVIHIPRHPHSPSSTFPVIHISHYPPFPVIHIPRYPHSPSSTFPVIHISHPHSRYPRYPHSPLSTFPVIHIPRSYNPHFPHYPHSPSSTFPVIPHSHHSTFPVIHIPRYPHSPSSTFPVIHIPHFPSSTFPGYPHSRYPHSPLSTFPIIHISRPYIPRYPHFGYPPVIHIPRHPHFPLSHISPLSTFPVIIPHPKSTFPVIHIPIIHISFPVIHIPRHPHFRLSTFPLIHISHYPHSPLSTSSTFYPHFPLSTNTAFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SP86</accession>
    <name>A0A423SP86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003001">
        <property type="protein sequence ID" value="ROT66017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SP86"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="42225" checksum="8CB5D1CF295DEE5C" modified="2019-05-08" version="1">MTRPPLMRSPEPCQSTVNYYSSPTIVNLISPPPSSTHIPPPAPHTQTPPQTLLACPYPYPPSSFSTPLLIPRTPPQIYPHTRCLPSLSYHRGYPSLTPTLTPHTPSSHSPYPTPTHTLVPSPTNPIPLLCPHTPFLPTLSTPLLPPPTPPPLPPHTHHTPPPTYPSTLSRKPYTPPMPSYPSQPLPSSSPHTTYPPYPLLPHTQVPSPANPIPILYPHTPLYPPYPPPLPYPHTHHTPSSHIPKYPLPQPYTPPIPSYLPTPTPLLSPIPTYPPYPLLPHTQVPSPANPIPILYPHTPPATPPYPSSSPYPHTHHTPSSHIPKYPLPQTLYLLYPHIPSPTLPILLSHTPYPPYPLLPHTKYPPMPSYPPPNPHPPSRESQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPE6</accession>
    <name>A0A423SPE6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002996">
        <property type="protein sequence ID" value="ROT66061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPE6"/>
    <dbReference type="OrthoDB" id="6356489at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="466"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="711"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="775"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="543"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="475"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="744"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="884"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1127" mass="123746" checksum="D152247B148A4DA4" modified="2019-05-08" version="1">MFDLDLQEELDEIEALLEREQELLGQQDHSHHTSVNLLHSPDQNWRPPKQFSQRQIRTPRSISRTQGNFAVPQNQLVALTRNMTFSDAEEDHQGSRNSQDASNSGGAGEGSSNHERSVSRSRTESGVSNASTASLVTPLSSAPPMANGQAPTESSDPTTPVASARASDLSNSEMSAAAAAVRNSTVADMKGVDSKKIVEKLHQIQGYIQQTTSAMSALEQQGDVSKIGQYNTLAKVLRDLRDSESKLKAYLESAKKSEAAAAAQAAAQAAGSPHNEETTTPASSSSREEVPVTTSSSGGGNQIVGIVGPGSVRSLQERLAMSQEESQEIMVRMRESIARREDLMTRYKATRERLENLKKQRRGLQEEEKRLLQSASSSETPSGSFDSPLPGSENWSNEEIETAITDFQVLYDKIDNLLTAYNAKAETIDPDDAQAVAEMNNKKEQILSKRRELIESLTCLRGIQQRRAQEGPSDGNETPSASTPHTQTNNTDTSQTPRVTTSNTGNEGATGNPHPLVARQQQSPPTDGEGAALSGLRNAVASVNMLSEEMTSKRSELQSLQKQLGDMKKLLEVTTAARQEDERRMIEAQQRLAKAENEHAMAAAAASRRDEQMEGAVGGEIVGVDGRKIQLSEAERKNPEIATKYREISQSKARLAMMEEALSMISTASRNRQNVRDVLPPEYLAILEDAEGSDLEDPIPRRVTTVPVIEEEPETEDKYKPSRRHAHSARMGARNREGATSTGRNEHNVRNEESREISAMQKRLNKTSTRISAINEGSRQGHEKGAIKKQPQALWREGGANVDPRVSEMIVMQEELRQKKNALEALMRRMGKPSSLNMDNISDNISDNISEPMDRLDGVSGTAATWGSGAMHDYSDNHYHQTSDEELLEEDMEGEVPMHSHRRPQQQLPPTPKDRNHQPGFSRQRRHHESSRLSVNNLATPQLERPKHNRFRSSSVPKAVWESVPTMDGRTYKSPSNTTLQAQQTIGSALSQLNQVQDTINGLRETLRHEQNQMISTSGGQYGSVVPQMMPDLATASLGTSPLPHMSGIAVSGVGAVTPMSAYAGLGSLGLAGQGGEMGSPMNQQMMSALQQCFSQLHLHSLEIQALSKHLQVRRPMFFPPYYPPYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPZ4</accession>
    <name>A0A423SPZ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002970">
        <property type="protein sequence ID" value="ROT66244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPZ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="958"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="602"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="958"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1211" mass="130554" checksum="92DE3412F4361B59" modified="2019-05-08" version="1">MFLLCLFALCCRRLTIFWYFFEYFHHHCFSKHFHHPFRTLPSLSTASSIFSLPLLPSSHSNTSTFFSNLPPSFYPFHHLSPPVPPSLSTPSTISLRPFHHLPAWRLSQPKVATESLRPRQTGRVSPPLASVASLCQRVLLFKQESAVSPPPPEAPNPHHHRVICFLTFQSFWVSLHKRGFHISLTPSTISALPILSTPSTIFSPSTIISLTLPPSLPLHISLPSHLSHPSPSLPPLPHLSPPSTISLHPFHIFSTHHLFHHLSPPLHPLPPSSLHPSTISLHNISLHPFHISIHPSTISLHPSTISLPPPPSLFHPSTSSLHHLSLSTISLPFPSSASTPSTSLSTPSTISLTPSNHLSPPLHHLSPPLPHLSPPLHLSPPFTISLPPLPPSLSTASTISLHPLPHLSPPFPSLSTPSTISLHPSSHLSPPFHHLSPPFHHSLSHPSTILSTLHILSTPSNHLSPPLPPSLSTLHHLSPLLTPSLSTSTSLSTPSTILSPPLQHFLHLSTSLFHTTLLPPSLSTPSTICSPPLSTTSSSLHPSTSLSTLPPTISLHPSPSLSTPFHHLSPPLHILLPLHHLLHRFPISLHPFHHLSPPPSPSLSTPSTISLHLHHLSPPPHSLSTSSFHNPSPSLSPSTILFSPLPPISLHPFHHLSPPSTISLHPFHHLFSTPPPSLSTPSTISLHPFTISLRPSTSLSTPSHLFHPPPSPPPSTIHPHISLHPFHSSHPSLSSTSLSTLPPSLSTPSNLSPPFHHLSPPFHPLSTLPPSLSAPSPFSLSLHPSTISLAPLPPSLSLHIFPPSPSLSTPSTSLSAPSTFSHPFPPLPPSLSTPSPSTIISPPLPSLHPPSLSPPLISLHPFHHLPLPSLSTLHHLSPPFHHLSPPLHHLSPPFQPSLSTLHISLHPFHHLSPPLHHLSPPFHISPPLSPSLSPFHLSLHPSNLSHALPHLLPPPPSLSTLSTSLSSPSSRPFHHLSHPPPSTLSTPPPLSIHLSPPLPPSLSHLSTDLLSSFPTISRPTPPPSLSTPSTSLPPPHFSTLPPSLSTPSTILSPPSTISLHPSTSLSTFPTISLSISLHLSTTLSTLHPLFHPPSLSTHISLHLHHLSTIHPSTISLTPSTIVGVSPNPKSRPRAFARGTLAACLLRWHLWRRCARGFIFKQESVVSPPPWKPLEAPGTTSSSGKSASSLFSRFGFPYISEGCFFLCDYCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQV8</accession>
    <name>A0A423SQV8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purple acid phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015396</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQV8"/>
    <dbReference type="STRING" id="6689.A0A423SQV8"/>
    <dbReference type="OrthoDB" id="6138663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00839">
        <property type="entry name" value="MPP_PAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.380">
        <property type="entry name" value="Purple acid phosphatase-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041792">
        <property type="entry name" value="MPP_PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025733">
        <property type="entry name" value="PAPs_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015914">
        <property type="entry name" value="PAPs_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008963">
        <property type="entry name" value="Purple_acid_Pase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867:SF3">
        <property type="entry name" value="ACID PHOSPHATASE TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45867">
        <property type="entry name" value="PURPLE ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14008">
        <property type="entry name" value="Metallophos_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16656">
        <property type="entry name" value="Pur_ac_phosph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49363">
        <property type="entry name" value="Purple acid phosphatase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Purple acid phosphatase N-terminal" evidence="7">
        <location>
            <begin position="56"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="158"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Purple acid phosphatase C-terminal" evidence="6">
        <location>
            <begin position="389"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="5">
        <location>
            <begin position="468"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="764" mass="87349" checksum="CBDDF445A8E35B28" modified="2019-05-08" version="1">MSSEVGERSAVIAEAFPPFVRKENVRMRSFTSWVILPILSGLLLTSAENRIDDYQPQHVHIVIGETSKDMVITWTTFTDTPSSVVEYGNAGLTQTATGSSTQFTDGGTEHRNLWMHRVILKDLQPDTMYFYHCGSQLGWSELFVFKTWKNGTDWPVSVAMYGDMGAVNAQSLPRLQEEVQRGMYDAVIHVGDFAYNMDSDNARVGDEFMRQIQPIAAYVPYLTCPGNHEQMYNFSNYRARFSMPNHEDTENLFFSWNMGPVHFIAVNTEAYYFLEYGLKPLSRQYDWLIKDLEEATKPEVRAERPWIILFGHRPMYCSNNDHDDCTRVNCLTRVGLPLVNLYAMEELLQKYGVDLAVWAHEHSYERLWPMYNYTVLNGSTEAPYTNPRAPVHITTGSAGCDENHDHFMPAQPDWSAFRAIDYGYTRVKIFNKTHMYWEQCRFSLRQNGSSSSEAALDGAPATGTPNVVLMSSMARSGSSFLGGLLSSLPGVFYFFEPLHNIEHWHMLSPATARDGLRGLLTCNITGAIRKAVRTRGKYTVYHPYTRRCATKEACFNSLLDETCRKEKFRVVKTIRARVSWLTSLLDDPEVDLRIIHLVRDPRGSVISNWKADWAPISEATSCQNLLSDLRDGARLRRQRPGKFLTVRYEDLCLDPRLMAEVILSFLGYSKLPQPTATYLDKQTKTTRDTKTYSLKRDTKSQQQKWRTTITDEEFARIEKACAASILLLGFNLFGSVEAARNLSLPLYNSSADHRAFDHRFCLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSG2</accession>
    <name>A0A423SSG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002849">
        <property type="protein sequence ID" value="ROT67096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSG2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="43093" checksum="ED7D97D85E786719" modified="2019-05-08" version="1">MPETSKQKLFKDPQRVTGQPLHVTSEWTLAFNLDDNLTVPHQAAEVDTTFPGDILVGMDLLRRLNFTLSHSTITNNAVLTLEGRSFQLSTLITKHSESVQSPATRLCQQHGRILFFYPTFNQLLLILLYSYPDSFSSRLHLFSHSFSPPLLVLSLVLSHSFSLGSFSYSFSYSFSTRSLLVLLLVLSLILSLILSLILSFSRSILSLTLVLSSFSRSFSPFLSFISPCSLAHSLLSRSSLLVLSFILSSSLSFSPRSLVHSLLVLSSSLLVLSLILSLVLSLILSSFSRSFSPRSLAHSLLVLSLILSSFSRSFSSRSLAHSLLVLSLILSSSLISSFSRHHSLSFSSFSRSFSPRSLAHSLLVLSLILSSFSLAHSLLVLSLILCSIAEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STQ5</accession>
    <name>A0A423STQ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative Y+L amino acid transporter 2 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_014336</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002798">
        <property type="protein sequence ID" value="ROT67586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STQ5"/>
    <dbReference type="STRING" id="6689.A0A423STQ5"/>
    <dbReference type="OrthoDB" id="3257095at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000003">
        <property type="entry name" value="Y+L amino acid transporter 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF240">
        <property type="entry name" value="LD25378P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT67586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="543" mass="60006" checksum="AF49DA0511AF783D" modified="2019-05-08" version="1">MPRQSNEALALRARARHLFLRSRHGHCQSDARVVAGHWTKPEKKKMPAKRIPTSETQEALTAAELEPMTPTEEKKEDNNGKTELKKELGLVEGIAIILGIIIGSGIFISPKGVLKETGSVGMSLVVWVLCGFLSMIGALCYAELGTSIPKSGGDYAYINTAFGSLPSFLFLWVANLIFVPTTNAIMGLTFAKYVIQPFFPECELPNSAVRLLAALAICFLTFINCWNVRLTTRLQNCFMVTKVGALCIVILAGLVTICMGNTQNFENSFEGTKTDPGSIAVSFYSGIFSYAGWNYLNFMTEELKNPFVNLPRAIYISLPLVTLVYVLANVGYLAVLTPTEMLASDAIAVTMADKLFPYCSWIMPILVAVSAFGGLSVHIMTSSRLCFVGARQGHFPDCLALINYKCNTPTPSLFFLGCFSLLYLCTTDIYSLIEYSSFVESLFILISIAGLLFMRWQRPNMIRPIRVNLLIPCAFFLICGFLVFLPLYVRPWEVGMGILITVSGIPAYFLFVYPQNKPALIRKLLDILTVGTQQLFLSVQGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUI5</accession>
    <name>A0A423SUI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002745">
        <property type="protein sequence ID" value="ROT67864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUI5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="42342" checksum="E93B2A6849070DF8" modified="2019-05-08" version="1">MLELMPRPPNQPMFNTRALRSVLFMGESPYSETVCADCRPFSPLLLPSSIIFFISSSFFSISFSPTFFTPTLSSLLASLITLLTYDPYPFHCPSLFTLLSLPLAPLPYSLLPSCFPNTPMALLPLLYRLPYSTSFLHDFYHTSPALFLLLLPSSSSSFFLLQFSLIPLSLFSFPSFSSRPLLFLPPLLSRFSSSSVLSSLLLLLSSPFYFFFFFFSPSFHHFLPLLKSAPLSSSLSTFPSLLLFFSLSPSLFSSLPLLLLLPPFFSLAPRSLSPPSLSLFLPSLPSSYNTSISFPLTLNASPSFTTSLFSPTSSHPPNPSLASSPSPLPSSPSSPFPLHSLLSPSPQSPSLLFLFSLLILLSLANTQICGFFLLSRPRPPSFSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SV15</accession>
    <name>A0A423SV15_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ammonium transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002726">
        <property type="protein sequence ID" value="ROT68018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SV15"/>
    <dbReference type="STRING" id="6689.A0A423SV15"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097272">
        <property type="term" value="P:ammonium homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11730:SF58">
        <property type="entry name" value="AMMONIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="6">
        <location>
            <begin position="2"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="106" mass="11772" checksum="9DEC0FA481B2CEBE" modified="2019-05-08" version="1">MISIGLFVKADSLLGMTGGKAGLFRGGGFYLLGVQTLACVVTSVWSMSVTYFLLTFIDKFVVSIRMSEWEELVGADFAEHGIRRRGVGGVARRVRVRIQSQWLRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVA9</accession>
    <name>A0A423SVA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013788</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002718">
        <property type="protein sequence ID" value="ROT68115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVA9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="515" mass="56676" checksum="6519959059A6C58F" modified="2019-05-08" version="1">MQEFLVHCIHLVDSYYLPVLLCFPFSLLVCYNIFFLLHSLLFLFLSYILLYFTILLTPFSSSFFFHFFPVFPFLLLPACFSLLRPSFPPFLFFFFSLPSSFFPPPFVFHFPPPFILFILSLCSSFLLLEPFSSLLLFFSFFHPFLFPFFPIPPPQPAILFSPIHPSPFHPLLSSTLTPLPLPSLSLFPHPSFLHPYPSFSTPLFPLPTLLSSPLPLFPTSLLFPPPLPSPYSPQPSSLSPTLPSSQPSLPSPPPSSLHPLPSFQPPTLPSPPPLPPPPLSSPLPSFHPRFFPPTLLSSTLPLLFSNPPLSSLSPILSLFPPPSSLFTPNLFSTPLFPPSHSPLFIPTPLSNPSSSLPPSITYFIPPTLLSSPLPLFPIPSFLPPTLLSLFTPTPPFPTPSSSRPPLPHPYLLLTLLSSPLPIFPIPSPLPFPPTSPYSHPTLLFFTPTPSLNPPPLLPPTHLPSSPLTSSQPPLLPPPHPPLHPPSSLTPSLSLFTPTPPTFPLNPPPLIPNGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVM0</accession>
    <name>A0A423SVM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013599</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002699">
        <property type="protein sequence ID" value="ROT68264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVM0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="42950" checksum="E40DF5EB0CF33DBD" modified="2019-05-08" version="1">MESGPRDQLAAPALSASVSVALFRPAALGSLSAREEMPRYIDGTGSGRPRALAGDWRGGRGNKVRRWFFVCLFVSVLLYSLLSSSYFSFTHIPSLYLRLFPSLCYNHLFLLPSPFSSSTLSFLTLSFSLSSILVSLPLSSYSILFSRLLLPFLPSFHPFPPSSPSSPFLSSLSSLPSPLLSSPFSSLLPHPVLLLPLSPRSPSPPSLTPPLYVSLSSLSPPHPRLPHPDPALPSPSPSLLTPRFSLSLPSLTSLPPSLTPSSPPLPSLTPFLLSSSPHPFSSPPSSRRPPSPPLPPSSPPPSPRFLSPSLTLPPLSLINPVSPSPSLLTPVLLSSPSLTRSSSPPPSPRSSPPPLTLPLLTPPPSPRSPSPPPSPRSPSPPHSSLSSSLSSSLSMQECSATCLSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZ01</accession>
    <name>A0A423SZ01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZ01"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="176" mass="19730" checksum="B68AE3615096CEB3" modified="2019-05-08" version="1">MELRKQMHFYLQVLAVLESFSRPSLHHDFENLDKGREVQVVQLEDGEYGVRVFERSQRRPILLPSQTWSIPPGWRAPGHEAARVVHAELLSSGDVVVVLYSPEDGLDLVVLPKEIFKPIEVTTNNAIIFPKVSVPWHPTVSTPAEDWTWPSDAEAVTPSGTGFRSAAPEKATLPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZ12</accession>
    <name>A0A423SZ12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012322</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZ12"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019380973" evidence="1">
        <location>
            <begin position="27"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="120" mass="13380" checksum="8BEAE10298A08FBD" modified="2019-05-08" version="1">MAFSWTSRAILLVAAVAVGLFITTKAEVPKEGHCIWYGMCHKNPQKNTTDKSMFLNCAYEGPAKLLENATAIDAMRHTVRKLLDEISKEERSYRLAAGFVMSKLQTERLSNHSTSTGLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2B8</accession>
    <name>A0A423T2B8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase CPPED1</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Calcineurin-like phosphoesterase domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_011037</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallophosphoesterase superfamily. CPPED1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002399">
        <property type="protein sequence ID" value="ROT70682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2B8"/>
    <dbReference type="STRING" id="6689.A0A423T2B8"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07395">
        <property type="entry name" value="MPP_CSTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041867">
        <property type="entry name" value="MPP_CSTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051918">
        <property type="entry name" value="STPP_CPPED1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="12">
        <location>
            <begin position="69"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT70682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="332" mass="38229" checksum="06126B83EBC3EDA4" modified="2019-05-08" version="1">MVEEDFVVLAKDRKFLPYYSDSQKEWKEPFFFIQAADTQFGMQEKYVEGKSGDYGWEQEMAWCRQMIADVNAMWPKPKFLVVCGDILDAMPDSEPEARRRQEVDFKRVFAGLDIPLVCVCGNHDVGNTPTPSTVAQWQTSFGDDYFSFWCGGVFFIVLNSQYYEDSSQAEALAAEQERWLEEQLEVVRREKPQHAVVFQHIPWFLRTPEEEKEYFNMEIGLRSAMLEKFHSAGVRYIFCGHYHRNAGGFYKDLEEVVTSAVGAQLGDAGHGYRLVRVLEDRLSHHYYRLGTAPTHIHLPKPYKSEPVSKGLARTWSFSQAADAVSRGWSIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7E5</accession>
    <name>A0A423T7E5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002167">
        <property type="protein sequence ID" value="ROT72374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7E5"/>
    <dbReference type="STRING" id="6689.A0A423T7E5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="44704" checksum="F5A8A78B26CE5F0A" modified="2019-05-08" version="1">MLLFKEIRSALPAIFPPPVPRAGRAGIRSRPPRIALPAARASSWAGHSKPPSPASRAGGHSKPPSPASPFRRPCIFAALPCSALPAARASSRAGRAFEAALPCIALPAARASSWAGRAFKAALPCSALPAARASSRAGRAFEAALPCSALPAARASSRAGRHSKPPPCALPAARASSRAGRAFEAALPCIALPAARASSRAGGHSKPPSPASPFRRPCLEGPGGHSPPSPASPFPPPVPRAGPGGHSKPPSPASPFPPPVPRAGPGGHSKPPSPASPFPPPVPRAGPGGHSKPPSPAAPFPARARAGPAGIRSHPPCIALPAARASSGPGGHSKPRIALPAARASSRPFEAALPCSRRPCLEPGRAAFEAALPCSALCLEPGRAFEAALPCSALPAARASSRAGRAFEAALPRTALPAARASSRAGRAFEAALPCSALPADPPVALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9R8</accession>
    <name>A0A423T9R8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008347</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002052">
        <property type="protein sequence ID" value="ROT73210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9R8"/>
    <dbReference type="OrthoDB" id="10507775at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="39825" checksum="F2158FAF995CFF62" modified="2019-05-08" version="1">MTVLPSVSERSIAVLVVGDFLEVFETKNNPVLRINKTKGMEFATDCKDSLTNVCLSCEQPAEAPPDVATTEPTPGGDSVWLPVAVALLVLLAIVALVSVAVCFRLRRRASSQEPEALRQSSACAQPALSSSPSPSLAEGKSPLGQRYSTLLASDAVAVPNGRSKGGGGGHRSQASRDLSGLPDLAPPPLPSTSPPSLPHHPDGASPPTEAADVRRTLEWQDNACHGDAKDPQEAPWSGADDGEGDYADPKELETPPILLGKDKEEAQRRSLAAEEGRLSSHDSENSLYEEMKALEAARETSALEERRRRERQQREEQEQQKQEIQEGKQEQQGDEEEKRQQKTVEEQEQNEQMKDSEQEILESVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA74</accession>
    <name>A0A423TA74_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_008161</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UPL family. TOM1/PTR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TA74"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin-protein ligase HACE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000007">
        <property type="entry name" value="E3 ubiquitin-protein ligase HUWE1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000004">
        <property type="entry name" value="E3 ubiquitin-protein ligase HUWE1, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000003">
        <property type="entry name" value="E3 ubiquitin-protein ligase UPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="11">
        <location>
            <begin position="1475"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="259"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="340"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="624"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="707"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="835"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1141"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1350"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="632"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="707"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="840"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1145"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1213"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1243"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="1778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT73389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1811" mass="197968" checksum="887EFDC0978E7B0C" modified="2019-05-08" version="1">MDHCYCWFLGLSLFLIHAIGCVLVLLGPSHRDALQLSSNLREATQVLFTNPDVRLMPPDPDEFIDMQDHGGTMMNNGGSSASLASVPNALSRWTEEARVLEADSMHDAVTVVKPALMAVLEKYRDAEQSERDKKKKEQEASKPPPASTETSQAPLLLLQSGDTEMGEATENNQTASGDQEQANQETTGQDAAILSTASIAESIVESVLGTSSGPVTTTATPSFSGLLTLLSPVSSGAPTLPLQEPPVSSVPAISGSLTSGVPSAPATPQTTTVSSLPPFPSPATSTSTPTLVAPTNTSSLEVEATSSTLTVNDTEMVAASPLPATGSTPISQDNVEALAAQEETPMSVSPPEYPSQSPELLASSGDAASTPPLPQVTPRDDWYDPSMTMQQDPPQDQSEDQAGAPPELAMPPAAESNTEGRSATTGSESNVAGPSGSNSNRPDYSAILGDIEIPEGVDPSFLAALPEEMRQEVIAEQLRLQRVRQRATENTRENNSTTVGEVNPEFLAALPPNIQEEVLAQQRLEQQRQQAARSNPDDPVDSVSFLQTLPPSLRQTILADLEDSQFAALPPELAQEAQTLRRQREERNRHAHEHMFSRTNASLSSILRNTARMGSRLMHSSSWSTSWNLRPSSSGQQASTTTTKPRGRQLLDHEAMTCLLVLLFVDEPKLNTGRLHRVLRYLCHHAPTRDWVIKALLSILERCGDPTLSSSRSAGPSTDLPMPSLPPITPEPASKCGGKKGTAGGRGDQAPLSSTPVWRSESRSPAAPSWLSMSMDAALGCRASIFQIHRTQPTGKRTSVASLTTAVNIHPQASPLVCRHALDTLISLAKSFPSHFLPHQGKETDDSKSDSKKSSSGMTTGAISKNSKGSSSSSQSSEPTDFWELLVKLDSISVSRKGKGLPRTHSSAGGNSEEEQRVASLEASALGQLIQQLAHPVIRRSSLLTDRLLRLLALISLGLPETADSASTQNSNTTTQHSVENSQTLEHLLKLAIQVLTSKSCSEEGLEDATALLLHLSHGPPPARDQVLRLLLQGAATLGSTVATHIAALLSDLRAYNASHPMASHEDEHQPHVTDKSKKGLLQDRFTNECIIISGATKVKPPCELQLASMSALTSKTSSQAFFLRTLKVIIQLRDAIRLSRTRRNAPQSNNTSERPTSGGQDAASNQEPTEGTGEDQTAASNNQEQSDAAASQDITETPSRTDTASSRDQLEENQQSQQQAQERSVEPAVSIDVPNPEADNAANASATPQEEATQPTAEAMDVDNETTETTELGSLSSQLNLDELWSTLSECLVELGETPDTHAVLVLQPAVEAFFLVHASGASGDRRERTTTQTESREAQLAHLHHEIAPLSPLPSVPTDDGEGASSQAGARKRENSTSQSDYSPGDTEKFLKFAETHRTVLNQILRQSTVHLADGPFSVLVDHTRLLDFDIKRKYFRTELERADDGMRREDLAVHVRREHVFEDSFRELHRRSPDEWKNRFYIVFEGEEGQDAGGLLREWYMIISREIFNPMYALFCTSPGDRVTYMINPASHCNSNHLSYFKFVGRVIAKAIYDNKLLECYFTRSFYKHILGKMVRVGDMESEDYSFYQGLIYLLEHNVADLGYELTFSTEVQEFGVTEVRDLKPNGRNIAVTEETKMEYIRLVCQMKMTGAIRKQLNAFLEGFYDIIPKRLISIFNEQELELLISGLPTIDIDDLRANTEYHKYQPNSLQIQWFWRALRSFDQAERAKFLQFVTGTSKVPLQGFVALEGMNGTQKFQIHRDDRSTDRLPSAHTCFNQLDLPVYETYDKLRHYLLKAIHECSEGFGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAD0</accession>
    <name>A0A423TAD0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Coiled-coil domain-containing protein C6orf97</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAD0"/>
    <dbReference type="STRING" id="6689.A0A423TAD0"/>
    <dbReference type="OrthoDB" id="6381883at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039139">
        <property type="entry name" value="CCDC170-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18863:SF6">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18863">
        <property type="entry name" value="TSEC-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="304" mass="34665" checksum="3A1C75017BEF2822" modified="2019-05-08" version="1">MGQEVTNDVEMIICRCQQLAKLEGEKIVDKTTTVYQLQRKVKSLREAVDRKDLHVDMLRRKLALTEDAARASRHLEEERDELIAKYKRQCRMVERLNSELGETRLQLRDLQAQLADAAEEKGRSTQQQKKVEELTAKINELDAIRSRQQKKITQMKEQIKAHGEHMLEERRVNENSLEGITQELAVTKQAVRDLTRREKQLQEFRRAVVSLLGLDGDPGAEGDYEAICRLERVVGAHRELNDLSRRIDEMTAPSRPNSRNSSLNGITSGCPNSARTLASRSPPLRSPTRPSSAAPPYRLDSPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBV5</accession>
    <name>A0A423TBV5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007648</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001975">
        <property type="protein sequence ID" value="ROT73891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBV5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="495" mass="53664" checksum="27A1BD5F0F5B8C33" modified="2019-05-08" version="1" fragment="single">MPLGNTSSIIFCLALPVNFPLTPSLLPLPLFFLLFPRLPLFSSSSSYSLVSLLIPSSPLSSSSCPLLISSVSSLFSASSSSYSLVSLSPPFLPFTLFFAASSPHAFFSFASSLSSSSPKFRLVSLSPPFLLLTPSSLLLPFLYSFFFLLLSPTPSLSFPLPFTLPLSSLFTPFFLPPKPPPLHLSSPFHSSSHLSPPPAPAPSPPSLVSSTPHLCFQILSFYLTLLLILSSPSLPFPHSSPLYPSFSLSPLFSASFSGPSLLSSTSTNHFLSSTLLLSIPFHPLLFHPPDLPPPFRLTPSTLLRPFHPTSSLLRPPPYSPPTLPPFHPFPASTLPPSFHPTFLHPSFHSPPRLPPSSPPLLPPLPPLHSSTPFPPYPATPHFPFPIHLATPSTPPLFHHPFHPFTRSTLSRPFRPYPPRPPSSTRLLHSPHPSHSYPPLFPPFFPPLPSPPSTPHPSPPPASTPLPPYLLPSLPLLHPLTWSLAPLSCSSDHASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEC8</accession>
    <name>A0A423TEC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative homeobox protein Nkx-6.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001850">
        <property type="protein sequence ID" value="ROT74747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEC8"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007417">
        <property type="term" value="P:central nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050877">
        <property type="entry name" value="EMX-VAX-Noto_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339:SF67">
        <property type="entry name" value="GNOT1 HOMEODOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24339">
        <property type="entry name" value="HOMEOBOX PROTEIN EMX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="94"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="19283" checksum="25E6A70B1FAE70CE" modified="2019-05-08" version="1">MDHLSVMPFQTHQWAFSQSWALPVSPPSTVTPNSPPTHRTLSRMSDKAKAFTIDALLGLDTQKDLPAPTASPPASPLSLLQRESSDTGLRDAPGKLKRHRTVFTDSQLQRLEEEFQRQQYLVGPERRNLARQLELSELQLKVWFQNRRIKWRKNQLNVNEFSSLPLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFP1</accession>
    <name>A0A423TFP1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="12">ARD'</shortName>
            <shortName evidence="12">Fe-ARD</shortName>
            <ecNumber evidence="12">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="12">ARD</shortName>
            <shortName evidence="12">Ni-ARD</shortName>
            <ecNumber evidence="12">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_006279</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <cofactor evidence="12">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="12">Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="12"/>
    <dbReference type="EC" id="1.13.11.53" evidence="12"/>
    <dbReference type="EMBL" id="QCYY01001803">
        <property type="protein sequence ID" value="ROT75195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFP1"/>
    <dbReference type="STRING" id="6689.A0A423TFP1"/>
    <dbReference type="OrthoDB" id="1867259at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010308">
        <property type="term" value="F:acireductone dioxygenase (Ni2+-requiring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010309">
        <property type="term" value="F:acireductone dioxygenase [iron(II)-requiring] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000031">
        <property type="entry name" value="1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03154">
        <property type="entry name" value="Salvage_MtnD_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027496">
        <property type="entry name" value="ARD_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418:SF0">
        <property type="entry name" value="ACIREDUCTONE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12 14" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4 12" id="KW-0533">Nickel</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <note>for iron-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <note>for nickel-dependent acireductone dioxygenase activity</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT75195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="181" mass="21515" checksum="FCE9054D7F3ECFF9" modified="2019-05-08" version="1">MVNAWLMDNSDEDKRNEHHLSPPEYVSLEKLRADTGVLYWKLDEKNFEPELEKIKSSRGYSYSDVIQVSPEKLPNYEEKLKIFYEEHIHTDEEIRFVLEGSGYFDVRNKEDKWIRIEVTPGDLLILPAGIYHRFTLDTKNYIKAMRLFVGVPVWTPHNRPADDMDARKEYVRMQKEGFSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THD1</accession>
    <name>A0A423THD1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001721">
        <property type="protein sequence ID" value="ROT75866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THD1"/>
    <dbReference type="OrthoDB" id="6365851at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="250" mass="26746" checksum="7A00EC7335532571" modified="2019-05-08" version="1">MTQHSIPSPCPLLFPPPISPPCPHPFLPAFLPCPPLPPPPPPLSQTHAAFLIKKDAPTTSLQCHSRSPRRSNRIPAASDMKLWVDVLLVLAVVLGPPVVTVGSLQYYGPEGVNCGLVLSGVYLMLVVVALVVRRKRQSAGGDDTLQAIRVADSPPPYEMVAAKPPPYSALFASAPPTDDVIRLANGTSHITRTYVPVHAPLQDPVSHKSSASPPTLSLARQESYDAGLPTYQEAVRYISLTAPVPRDSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TM52</accession>
    <name>A0A423TM52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001512">
        <property type="protein sequence ID" value="ROT77537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TM52"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019147977" evidence="2">
        <location>
            <begin position="24"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="46251" checksum="929C8B4161B936AA" modified="2019-05-08" version="1">MDRFRQWFLIWEALLLKNRVADAMLMLQGVSTDNADESGNTPGTSSDSTLTSSHSQGRGKRGVLQRQHGIIRDAAGEERREENREATHQQQHSQQSQHPQQQQTPQESGKSDTKDAKGEAEKEPELIIPDTVVVSAGTVTLSSNQPALLQVPTMLMGHRDSIGPGPLPKQHSHPTPLLTPTPIISKQLSHPESRGPPTHQGPPQMSKQRSHPGVLTHTPSPSERLPSTTTTTSTSSTAPQQQQHLQVIPMHLVVKPRAPPVTMPSQLRPIQPKPCEGPAVSEPLPKKEIPLIRLTPSEDGGNVNISSSGFNMSGCTVTGPSRPIRALSEEPAMSRQSMTHTHEQLAPGPSVLIQSVSQDSGLDSGTGNRMLSTPQLSVTTTPPLRPASSPGHCPVLRGGPALGCNLYRAEEHSFGTPLQVTVPSFVVVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMI8</accession>
    <name>A0A423TMI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001494">
        <property type="protein sequence ID" value="ROT77676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMI8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="49999" checksum="8C4D50615BF076A8" modified="2019-05-08" version="1">MQLSPHVRLQSFTDGELQVGTSDKLQSRDGDRLEGGRFLFVYFYFFSLSSPRPPLFLSFSLSSLFLSSSSSFLFLSSFFFVSFLSLLILSFFLSSSLFLLNIILLLLLALPLTSHSYPLLLSLPSAFHFLSLFYFYSSISLSFLSRSIPSIFYSSLLFQFSIPPFSSFFVTSFHILLFPSLSSHPLFISLSLSSYSLPRSSFSSLPFSFLPPLLISFLFILLIIIIIITILPCFFSSSSFFPFFSFSSSSFFSPFLFLLLLLFFSSFCFYFFVLLLLLLSLSFSSLPPFTSLSFAFTFFPSYFFFSFSFFSFLFSPFLFLLLLLLLLSLSFSSPSSSFPHFSFSFSSFSLFLFLLLLLLLLPSFIPLYRAERSSSIKPRPPTSKMDQSYPARCGLDQSRVTSLTDHALLARDLRPGPSCVSRGPSSLPFRASPVGPNASTGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMP0</accession>
    <name>A0A423TMP0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001488">
        <property type="protein sequence ID" value="ROT77728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMP0"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="4">
        <location>
            <begin position="150"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="658" mass="73389" checksum="1EA462DDFF805C87" modified="2019-05-08" version="1">MNLTPVPLEIRGGVPVLNFEFTDLPIREFDLPTPSPVCAASHSPPQSLNMRKSCVRYFERLASAGLTINPGKCQFFRSKLDFLGHTLTSNGIAPNQNKVQAVIDFPRPQNQKDLKSFLGLSGFYRPFIKDYGSIAQPLTTLLKKDVPFEWAKETEDSFLQLKALLANAPVLAFPDFELPFVLTTDASSVGLGATLHQKVNGKLRPIAFASRTLKPAERSYHTTDRELLAITYALRHFRELILGYKIEVHTDHSALTTALHGRDPHGRRARAIEVLAEYDVTIVYLPGRQNVVADALSAHPCHPPRNYRPMLVLMLLAMASPLLAEPGLPERLRAVPGALIENLGTVFPISSNIEVRVSLRPLSDISNIAIHHLNEITRLRNEIAEDNLSHEKFFLLDKAINSTMFTLQQFVVHKRRSRRGLINIVGKVAHSLFASKGTVSESLISPQDIDLILKQAASHKLHPLFTLTDRVPFYSTLKSFLTISGHTITTPPPTFMTACTQALPRLFVCNSRPLPLFSDDCSDAIITNHNIINECSFDSIVPTSRPFLLPFDDISVLYFFQPSTATVVQRGSSRRCSYRNLCPPYLLRDCDNVVIHSGVPFIRNRHIRPWSQHQPHGTGCARFRSTYHHSDTCQKSRASQPVNPDAPTPGRHLATAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQY2</accession>
    <name>A0A423TQY2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc finger and SCAN domain-containing protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001319">
        <property type="protein sequence ID" value="ROT78867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQY2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1163" mass="129079" checksum="FD9A1A4C92109799" modified="2019-05-08" version="1">MLPCRRCSSAERCPAEGAPLQKGCSSAEGARMLLAEEAPLQEGCSVQKDTLPAEGCSPRRCQKMQKEDASLAEGCSLAEGCSLAEGCSPRRKMLEKEPPAEGCSLQKDAPSAEGDLPCRRMLPCRRMIPCRKDASSAERCSLARRMLPVKSSVQKDAPLQKDASPPAEGCSLARRISLLPCRRCSPQKMPCRRMLPCRRMLPAKMLQCREDVRVAKDAPRRRMLPCRRMLLGRKDAPKDAPRAEGCSRQKDVPSMQKDVLCLAEGCIHARRCPLQKGCSRGERCSSQEGAFCKDAPGQKMLPAEDAPCRRIAPVQKDAPVARRRMLPCRRMLPRRRMLPRRRMLLAEDAPSRRMLPVQKCSRPAKMLPQKELPCARRCSSAEAEDAPVQKDAPSQKDAPKDAPFQKDAPVQKDARVSMPAVCSPAEGCSLLCMLPWQKDAPLQDAPRRRIAPARRMLLAEGCSLVEEVRAEVCSLAEALADDAPQQDAPCRISLAEDASQCRRFAPFQKDAPVAEDAPMQKDLPRRRCSRAEGCSLAEGCSRAEGCSRAEGCSRAEGCSSAEGCSSKDAPLQKDPVQKKGSSAEGCSAADAPVEGCSSAEGSLARDAPLQKDAPVQKDAPLQKDAPVQKDAPVQKDAPVCSSARRMLPCRRMLPCLQKGCSSAEDAPLQEECLSEGCSLRRSPCRRYSSAEGLLPPCRQAMLQCRRMLQCRRMLQCRRMLPCRRMLPRRRMLQCRRMLPRLPVEGCSLQKDAPVAEGCSSAEGCSLQKDAPLERDAPLAGRMLPAEGCSQCRKACFLAKDLPKDAPCRRMLPCRRMLQCRRMLPCRRMLPCRRMLPCRRMLRERLPCRRMLPCRRCSLAEGILEDVQKDLPCRRCDAPLQKDAPLQKDAPAEGMLPCRRMLPCRRMLPCRRMLQCRRMLLAEGCSVQKDALAPQRMPCRRSSLQKMLPEKDAPSCRSMLPRRRMLPCKKDAPCKEEFHCRRMPRRRKQKMLPAEGCSRTEGCLQKEAPCRGCSSAEGCSLAEGCSLAEGCPRAGKMLPCRRMLPCMQKASLRKELLAEGCSQCRRMLPLQKECSSQRNASRAKGCSLAEVLPVKDEKDAPVQKDAFQCRRDAPVQKNAPVQKDAPCREDAPVQNRMPQCRRVLPAHAPCRRCSVPCSPQKACP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRD7</accession>
    <name>A0A423TRD7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hydroxylysine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_002242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001301">
        <property type="protein sequence ID" value="ROT79026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRD7"/>
    <dbReference type="STRING" id="6689.A0A423TRD7"/>
    <dbReference type="OrthoDB" id="9973935at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019202">
        <property type="term" value="F:amino acid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000549">
        <property type="entry name" value="hydroxylysine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050249">
        <property type="entry name" value="Pseudomonas-type_ThrB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21064">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21064:SF1">
        <property type="entry name" value="HYDROXYLYSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="261" mass="28920" checksum="73E8CE8EEE797971" modified="2019-05-08" version="1">MALLPSYRLSPLSWRHLSVTDHSCHPSVTDHSVTLLSQITPVTPLSQITPVTLPSQITPVTLPSQITPVTLPSQITPATLLHPLHPAAHSYFLLYHILHPFSTADPTQPTLHSPVLQLAMSSMPEASDAHGLLQPGQIIRPMLKKADVPALVGKLYGLTVVSVKELNSYDDKNYLIQVQSKVNNPHMTDLCPHGYVVKVTNSLDSKNIHLMAAQNDMMLFLHSRGINVPKPEKNVHGTYMVKEKMEIFLSKGDKYFQDLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUK5</accession>
    <name>A0A423TUK5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001153">
        <property type="protein sequence ID" value="ROT80092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUK5"/>
    <dbReference type="STRING" id="6689.A0A423TUK5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="540" mass="59315" checksum="95276FE7E19F9C5D" modified="2019-05-08" version="1">MSVFYRPSFSRPFSLSPLFPSLSRTFCLRFPFHAFFISPLLLSYPLLYLPSLFPSLYLSSSAFLFNSFSASPLTFFHFSIPPFPYPFFFHFCFLHLNLPHYIFFFVLFNLLSHSSLPLSHLFLPLFLPTFPLYLPLFLSLFHILFVLVRSTISLLPLPSSSPYSSPFCLFHHPLPFPYCTHLPSFFIASSSSPSPLHSLFFLFPSLFSLSKFITSDSPSLSLPLISSSTFSPLLSPYSPFSFSILLSPSFPTLLPSSLSSPFLPSLPPSFSFLSSHILSVLPSLSFQHFPLHSPLIATPPLSLSRFSLPLIAIPPPAPSLPSLPSPHNPKPSLPCPYHPPSLSPLFPPPLNTLLTSAPSLPLHNPNPISPLSPSPHHPKPSLPSPYNPNPLSLLFPSSRNHQPSLPSFPLITPNLLSPVLITLLSSFPPPLITLALSPPHNPTPLSHLPPSPHNPNHLSCAQHSSSLFPLITPIPLSPHNPPLSPLTPNNPRLSPLTTPIPLSPHNPKTSLSCAHHPPSLSPLLHNPRPSLPLPPPPSTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUU1</accession>
    <name>A0A423TUU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001139">
        <property type="protein sequence ID" value="ROT80227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUU1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1151" mass="117617" checksum="F78BE21EA1174634" modified="2019-05-08" version="1">MGGPKTPSASQQVNPGLKWAALNARKCTSHFEETRVFALTSRLSLPQRHNRLAVKRTFPSPLVSPPGGLPLANDEKRREMTRNRRSAARTAGAPAPWLPLLLPPWLLGSPPSSSLAPPPWLSLAPLLGSLAPPWLSFLSLAPPPWLLAPPPWLLLLGSPSLAPWLPLLGSPSLAPPPWLLLGSLAPPPWLPLLGSPSLAPPPWLPLLGSSLGLPLLGLLGSLLLGSPSLGSLAPLGSPSLAPLLGSPGSWLLLLGSPSLAPSLAPLLGSPSLAPPPWLLLGSCSLAPPPWLLLLGSPSLAPPPWLPLSLAPPLLAPWPLLGSLLLGSLLGSPSLASPSLAPPGSSSLAPPPWLPPPWLPPWLPLLGSLAPGPSLAPPLGSLLLGSPSLAPSPPWLLQGAPPASPPWLPLLGPPPWLSLALLLGSPPWLSLLGSCSLAPSSLLPLLGPPPWAPWLPPWLLAPWLPSLAPPSLAPPPWLPLLGLLLGSPPWLPPPWLRSFLGSPSLVPLLPPWLPPPCSSSLAPLLGSSSLLGSPSFPSLGPPPWWLLAPLLGSLAPLLLSLAPPPWLLLGSSCSSLLGSSLLLPWLSLAPPLLPSLFSLLGLPLLGSSLLCSLAPPPWLPLLGSSLASSSWLLPWAPPPAPWLLAPWLLLLGFPLPPSLAPLLGLLAPPPWLPLLALLLGSPLPCPFAPPLAPPLAPPLAPPLAPLSWLPLLGSSSLGFPLLGLPLSGSSSLAPSLAPLLAPLLGSSSLAPPPWLPSLLSLAPPPWLPLLGSSSLALLASLLGSPPWLPPLLAPLLGSSSLAPSSLAPLLGSSSLGSLLPWLLGSPPWLPPPGSPSLAPLLGSPWLSLASLAPPPWLSPLGSPSLAPPPPGSPPWAPPPWPPSSPSLAPAPCSCSWLPSLAPSSLALLLGSPSLAPPLLVLLGSSLGSPPWLPLLGSSSLAPASSFPCSLAPPPCSPPWLLLGSPSLASFLLGSPSLALLLGSPPWAPPPCSFLLLGSSPWLPLLGSPSPSPPWLPPPLGSPSLAPPLWLPLLGSSSLAPPLWLPLLGSSSLLPPPPGSPSLLPPPCSPSWLLSLVPLPPLPLLAPPPWLPSLAPSLAPPPPGSSPPWLPPLWLPSWSSSLASPPSSPWLLPWAPPSFSSLAPPWLPLWLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWA7</accession>
    <name>A0A423TWA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Putative stromal interaction molecule-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_000502</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Endomembrane system</location>
            <topology evidence="13">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001074">
        <property type="protein sequence ID" value="ROT80744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWA7"/>
    <dbReference type="STRING" id="6689.A0A423TWA7"/>
    <dbReference type="OrthoDB" id="9986177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005246">
        <property type="term" value="F:calcium channel regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051049">
        <property type="term" value="P:regulation of transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002115">
        <property type="term" value="P:store-operated calcium entry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09504">
        <property type="entry name" value="SAM_STIM-1_2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.50:FF:000009">
        <property type="entry name" value="Stromal interaction molecule 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.180:FF:000001">
        <property type="entry name" value="Stromal interaction molecule 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057835">
        <property type="entry name" value="EF-hand_STIM1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032393">
        <property type="entry name" value="SOAR_STIM1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037608">
        <property type="entry name" value="STIM1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15136">
        <property type="entry name" value="STROMAL INTERACTION MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15136:SF5">
        <property type="entry name" value="STROMAL INTERACTION MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25578">
        <property type="entry name" value="EF-hand_STIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16533">
        <property type="entry name" value="SOAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAM" evidence="16">
        <location>
            <begin position="86"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="215"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="470"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="473"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="503"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="558"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT80744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="632" mass="71333" checksum="C0CF9963082C162F" modified="2019-05-08" version="1" fragment="single">CVPVDELCLVPEEVPNYEAIKSLHSQLDDDRSGDIDVSESVEFLKEELQYAKGYEKRQKVFHSNNDQYISVRELWHMWKKSEVHNWTVEQTVSWLAESVELQQYAQNFYANAVNGSVLPRLAANNEQFLTKVLGIKDPKHRSKITIKAMDVVLFGPPKGSHVKDLVLVSLLTLALIGCFKAYQRNRQYEGQLSDMLRDMEKLKEAEENLRHLEQRVQTNTKAEERQMSEENKEHNEEVQLLKQQLEEEREKNEQMKEQMKWSAPQDLQHWLQLTYERERLAFEKKQRGAREQFSQARDLCEKLNRQRRSLLGMITSVNGKMENIDQSISQARTIMEEVTQELREREQRWQNIEVLAGCSIITNAGLHALELMLRPQVNGRPHSTYAPSIGASSCYGGVAINSSGLGGTPRDSMVDVRGSVGSVRKRSQLLTRDSGSSLGSEASITQTTIMHHSQTYTAGMGLHSEEEECIRRASSTGSITVTDCPQSKDSESSTEETDGSACVSETTSFSMGGSRLTLNSECSRTISPVQEREKISASEPALDSPRTSSMLNKKKGASPSEEGNSSDSSMMEERPPSADSRKKSKSWFRNGISSSLKFSRSKKLKETDKDSSKNNTKHLSADFCLHASQYAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TX45</accession>
    <name>A0A423TX45_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-type lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000202</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001033">
        <property type="protein sequence ID" value="ROT81043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TX45"/>
    <dbReference type="OrthoDB" id="7755331at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050801">
        <property type="entry name" value="Ca-Dep_Lectins_ImmuneDev"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22801:SF63">
        <property type="entry name" value="C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22801">
        <property type="entry name" value="LITHOSTATHINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="135"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="28345" checksum="F6F31741D8859C18" modified="2019-05-08" version="1">MRACYALPSSSSPSRPYPPVPPLEALPSSPSLLSPPRGPPLQFLPSRPSSPVLPSTPMPPPRPLLLALTVAFGAAASVPSAAPATSDVPGYFLNMLMWSGDESERYHRSPLVPAALTAASSSLAAAACPAPFLPVMSQCFWSSAQYKLSWDDARDFCQQMGGDLAEPLHLNALMVHLQDRYPSAKVFHLGATDLEQEGNWTYISGRPVDPRGWMPGEPNDTAHAQNCLNLCFQGCRASYPPLNDQQCHAKFHFVCEFSVARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZE4</accession>
    <name>A0A423TZE4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000913">
        <property type="protein sequence ID" value="ROT81825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZE4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="34946" checksum="FC993C89019D94C6" modified="2019-05-08" version="1">MKISPRIGSHSNEDEAVVSENGGGSPPITAFRLLQSNSSHNQQRYTDKSTDADPHGAQASRTSSSTEEMTTNQEGISSSLAQLVQNQTLVATLLSELVAGQKQLVASQKDMLAVARDGSLIRNAPIKRKRTTAEVSSRTTNYLYHVRVNHAEFRVCRIGFLSIYGIGKKKLEILLRKRKDSPNGTPVLDKRGKKPSPRSITGSILASVQEHIQTLPVTSSHYSLTTTPHCGYQEDGTSIGTDYQDTKRNITKARLMNDYARYTRATFNPSNVALAQKYTHDRHQGLRASKADNNSPEEDDPEKDILDNVPLPHPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1D8</accession>
    <name>A0A423U1D8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024307</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000811">
        <property type="protein sequence ID" value="ROT82523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1D8"/>
    <dbReference type="OrthoDB" id="6360870at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00003">
        <property type="entry name" value="4DISULPHCORE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019473118" description="WAP domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="26"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="102" mass="11125" checksum="840DCB557609CBB6" modified="2019-05-08" version="1">MSSTAVRVCALLLVVLMVQNSWAGRPREKPGVCPAFPAPPPPPGGIDFSPDKLGFERTGCRGDYECEGDLKCCAAGVCCHFFCTKPLDRPHWIGLCLDRLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3C8</accession>
    <name>A0A423U3C8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative BAG domain-containing protein Samui isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000721">
        <property type="protein sequence ID" value="ROT83194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3C8"/>
    <dbReference type="STRING" id="6689.A0A423U3C8"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="534"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="456"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="664" mass="74541" checksum="5318C7803A30094C" modified="2019-05-08" version="1">MWPSHIAKPLQRAPVKRSQCPAPRCVSSAICSLRRERLFSMTSAATGERDLGRSPPLFSSSLSSALSAEDGEDLARRCMGDLRGRHGMFRMPDWMSEDDDMSDLAHRMSHAPHFATMGRRGGPWRERRSSGGSAMSATSEDDSCDAAATDKSSQCSGGSTEGPATSHEIPIRLEAPAPPSASRQQQQQVENEPVAPLRTSHARNAPQYPVRTTSAVDASDHSRDVPRSTRCASAPPEMAEQPLQPQASQASPQQQRFVSKISITPQAPQGPGTPPAKPASPLPAKFNTIPKPFVPANKTQTQTAPQEQQQQPFEEQQQHGHMASPQMQYQQPPQPQQQVPSQTTPQYQQQYQQQQPQFHQQYHQQQPQYQQQYHQQQPQYQQQYHQTPLQQQQQSPRQSGQRPSVVRNIPIFVEGRDGPLVNEESGTPPKPAPQWGQQWQQPQPQQNQHPQPPLPQQQRQQFKQQNQPQQPQSQPIPQPVPMPMPQPHSQPQAQTPPQQQQQQQQQLQQQQQQAEPKPPQPAKDPRLSQIESVKASVDEYRAKVEAFSGSKKSREFLYLDEMLTRALLQLDNVDPDGRDDVRQARRAVIKDINAAISLLESKAAEPEQAQKEKTPTPVATHEAAAEPKVDSEATEENRTTEEEKAAEQKTEENRLRRKVPRSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5R2</accession>
    <name>A0A423U5R2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Synaptotagmin-17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000603">
        <property type="protein sequence ID" value="ROT84046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5R2"/>
    <dbReference type="STRING" id="6689.A0A423U5R2"/>
    <dbReference type="OrthoDB" id="6373064at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="176"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="326" mass="35836" checksum="329777A8A48DE350" modified="2019-05-08" version="1">MPEPACVRPAAGGVADPAKECYGAVTLKVLSRQGRWVRVLVCGLSGLPWVGGSGGLMLEVNIEPGGRPRWLVLPHAHGPNVNVKLEAVVKQPREIKTKKKFLVKVGVWVCGRVWRHAALGHALTPLREPGNPVTAQLLHHTQLTEDLGLVEVSLRCDYSDNLMKQVVGTSMAEVILTLEVLRAKNLRPFNPGLLSKAKHSKKKEHAEVVCRVGLWVKGERVERKSSTSVKLPVTHDPVIRNRSVFNIPRDHLQNAALIVKVLYTSKWAGEDTVGRVKLGPLLYLGTSPDQASVNPQPDYNTSITLSHWGQALKTPGPVTMWHHLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6P6</accession>
    <name>A0A423U6P6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000556">
        <property type="protein sequence ID" value="ROT84362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6P6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="685" mass="75974" checksum="4157A7F1265A15BF" modified="2019-05-08" version="1" fragment="single">SVFLFFFSFGHFAYFIYLLFHLLFFLCLSFFPLLSPFIFSCLSFSLSIALFTLLLRLLLFFLSLLPCSCYFSLSLSSSRFFALLAYFLFPFSLPPSCLFPFLDFLLFFLFLLASSLPLFSYPFPSFLSSLFPFHLSSSCSSSSFPLSHFLLFFSTSPSLLPILASPFLPSFPSLSYLRFRFLNHSYSPLLIYLPSSPLLPLFLFFLPLFLFSSPLSLLISSHFPSSLLISSHFSFSSRILLFPFFSHSILSSLPSLPLSLFVSPTRFPSSSFSTTLPISLPLSLFVSPTRSFFVFLSPLLFFSYPFPFPLPLPPLPISSFSFLLSPHFFSLPFLLSSSPLPPFPPLLSSLPLFLSIFLFLSPLLVFPLPVPSLPLFSSSYPSSFLFSSFSLHSSSFSFLLFPLSSLLFILTPSSSSSSPPPPLTSFSLPSLSLSHLLASLFPLLAFLLPVPSLHFLLLFSSLSPLLLAFLHPIISHFQVSRSVALSLSFILLLSYIYADTVKTRDRRVRWIRMRGYRKLCNTPCLLGSASSPLFSLPPSLSPLSTSLALLTLPALFRSSLPLSSFYSPPPSAFSLSPSLSVLIVPPFPSRPTGLFSSCLPPAPRAFHPLLPLSPLSLLRRLPCLSPLSLLTSLAFPLISPLSLSLPSLVNPSSFYLSSPSFSAPLFISFTLRLCAHLPISIPSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7C7</accession>
    <name>A0A423U7C7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000520">
        <property type="protein sequence ID" value="ROT84620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7C7"/>
    <dbReference type="OrthoDB" id="10059697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054465">
        <property type="entry name" value="Integrase_p58-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22938">
        <property type="entry name" value="Integrase_p58_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="351"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="651" mass="74109" checksum="E98547E0D5C34453" modified="2019-05-08" version="1">MRPFARSTHPYYRSRKEFLQIPSGGTLKETIDGKAPKLRDSPPEDVSCEDLGSLEISTAEAVTPDSGYRGSALGALNESIEQHGFIEDGFESFDACLDFGYEPDEFFVFPETPAIDESCQICNEPQLDVASATPSPNTDGSNLLEEQLSLNHLTCEQKSQLTDILRSFPRLYTGNKHTETLLLTLSPILIPHCWKYPLQCRISRCKNRNHIRCPTSQPWPQQMREQQLQDPVCTDLIAWLERRQSLPKIRLPAAISDFELYDGVLYHLRHFPDRVVKQIYVPHQLCNQALHLAHQPPTAAHPGALRTYQNLCNNWFFPNMLHLARTYVASCETCQRRKAPVVRAPMQGHPPSKAPLEMVSADLMDLRRSAQGFRYVLSIIDHHTRYLQLVPLRDKSASRVLKAFVDHFITLFGPPAQLHTDNGLEFSSDEWRSLLKELEVRHSFSVAYHPQSNGVVERSNRVVKDALAALVQQSPSQWPIHLPAVRFALNSAIHRSTSDQPLYLLTGRMALFPRGLTNLQTIDEGQMVKCLADARRIAIKTTLETREANKRYYDRKAKPLHLNEGSLVLRKVEGSTRALDSRWKGPFRVLKKIGPVTYDILELQQPHRTMRVHANQLRPFVPASEIDFVEEGDQLPYPLVNFEFDAAPRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7M6</accession>
    <name>A0A423U7M6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000508">
        <property type="protein sequence ID" value="ROT84705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7M6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="603"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="683" mass="76447" checksum="88D577AE3E86CFF2" modified="2019-05-08" version="1" fragment="single">TKPTERHPRTPNALISPRSGKRTQISRSFTQNALRSHAPHQIPLPHANALNAPHANALPRSSTQTHSIQLPSQRTQIPPSQQNALRFHAPHANALRFPPHATHLTLSRKRTQIPSSLTQTHSDPRSLTLRFTLIRFPRSLTQTHSDSHAPFTQTHSDSHLPHANDSDSHAPSRKRSDPTHSIPTLPHANALRFPRSLTQTHSDSHAPFTQTHSDSHAPHANALRLHAPSRKTHSDSHAPSRKRTQIPTLPHAKRTQIPTLPHANALRFPRLPHANALKIRTQIPRSLNANALRFPRSFTQSTQIPFRTLRFPAPSRKTHSDSHAPSRKRTQIPTQRKRTQIPTAPSRKRTQIHAPHAKHSALLTQTHSDSHAPSRKTHSDSHAPSRKRTQTSLTQRTQIPRSHALRFHGKRTQPHAHQIPTLPTQTHSDSHAPSRKRTQIPTLPHANALRFPRSLTQTHSDFPRSFTQALRFSRDSDSRSSRKRTQIPTLLTQTHSDSHAPSRKRTQIPTLPHAQTHSDSHALTTHSDSTLPHANALRFPRSLTQTHSDSTLPHATHSDSHAPHANATTLPHANALRFPRSLTQTHSDSHAPHENAQIPTLTQTHSDSHALTQRTPAPSRNALRFQQTHSDSTLPSRKRTQIPTLPHASTPQNVKSSASRALDLSPNKICKFSRFFGGKMKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U836</accession>
    <name>A0A423U836_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000481">
        <property type="protein sequence ID" value="ROT84877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U836"/>
    <dbReference type="OrthoDB" id="6362496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="51456" checksum="96D80505122FF11A" modified="2019-05-08" version="1">MSLEGEISSEVHEDLEDIPSTEWEKSLAISPTALSCISAPYDEDVDLGVGEVQEFVNESDNKEKRRKKSHHRRFTVPVVTADMQEVVASQSEDIRMDTKAEMFAETLQVPMAQKLLHLKYDELSYADTESESIVDASLMSGSDKGLAYIESCLRGRIFSGWVEERKWVENLGSYRDIVEVDEWEVDFNKQLNIIIRKIPGVQEGTRWINITAPTAVQLSYCLWVLLIQPPIPGHYWFVITGVAVQPLFGLKISLQIVRSIDPQDYETAEARSKRRQISSSELGHELETISQQFMDWWDQVRQLNFALVWSAVTATFTISNILEAVRFCIILVITLIVGLVTLLRDSYHFVLGVIHEAGIFFRNLRPFLQSVVLFVEKLIGGLYLLLAMVYRDWKQPSPQSASPSPVTRHTLQPSKSDHPHVPTCSPAVPRTVKYVPPQQWVYKRQTSNPLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA52</accession>
    <name>A0A423UA52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000245">
        <property type="protein sequence ID" value="ROT85576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA52"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019495903" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="147" mass="15451" checksum="BB524D2A9563719B" modified="2019-05-08" version="1">MKFLIVATLLALGVATASSALVDESEPATAAVKILGGYVTRTRFTTLFSTTLKTCITQVGQNAQCQGRKKREAKALNENLMAADNVREVLLDSSQGEKVEAVGPQAASSSSPSIASHLGRPCPTVSLLPPRGPHVRLLLSADEQFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB49</accession>
    <name>A0A423UB49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000157">
        <property type="protein sequence ID" value="ROT85895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB49"/>
    <dbReference type="STRING" id="6689.A0A423UB49"/>
    <dbReference type="OrthoDB" id="6373298at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="21480" checksum="AB36BC159EBFC3B3" modified="2019-05-08" version="1" fragment="single">MSVCEALHPALERLDSEHLSRFKLNWVTVNMHVFHSTILTDPDVHDYAQICKEKFRETPGGEDVLSCLASLHRTLAVAEAVWVRADTLLQEYAIERAALSARRRQLLADWEQFKAQQRTQQQEAAKAGVPNLASTSAALSEDGGAQCPCDDCVNGRTGQLEGQPLSGNARIALSSSPDVRSPSSCECHFCNASMAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSH0</accession>
    <name>A0A3R7LSH0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.130</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Coenzyme Q biosynthesis protein 4 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020411</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid into 2-methoxy-6-(all-trans-polyprenyl)phenol during ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H(+) = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:81179"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="4.1.1.130"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of a multi-subunit COQ enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the COQ4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.130" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01003991">
        <property type="protein sequence ID" value="ROT61780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSH0"/>
    <dbReference type="STRING" id="6689.A0A3R7LSH0"/>
    <dbReference type="OrthoDB" id="4249at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120539">
        <property type="term" value="F:4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03111">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007715">
        <property type="entry name" value="Coq4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027540">
        <property type="entry name" value="Coq4_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05019">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="299" mass="34041" checksum="7966C60CD3A21C19" modified="2019-04-10" version="1">MLQVGFFSRKWRPELIRNLGRLSHSCARGAHTIADETGMKADSSEAREIPIRHSREKIDDDSKSNQQVKEEKALPLYKHHIPTDIFQKTLLTVGAAAAALLDPRRHDMVAVLGETTGYTALSKIYAMMIEDEEGRQILIDKPRINSSTLNLPFLRQLPEGTLGHAYIKFLDDNQVTPDSRLPVQFVDDPELAYVMQRYREGHDLFHTVLGMPTNMLGEVAVKWIEGIQTGLPMCVGGAIFGPLRFRPKQRQKYISEYLPWAVRVGRSSKLLMNVYFEKRWEQSLTELRDELGIESPPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZZ3</accession>
    <name>A0A3R7LZZ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003417">
        <property type="protein sequence ID" value="ROT63578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZZ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="41371" checksum="0423F5A274297E03" modified="2019-04-10" version="1">MVNYFYFPHYYGPVHPFTPPPLIPQNILTPPSPFPFLFLFLPSPPTPLRPFTLFYSFSPPPSHPLCLPFPPHPTLFPLILSPLLPLPILISLSPPFPSHPHPALPPLAPPSNSSHPPASLFPRLLLFPPPFPPPIFLLPLIPSHPLPYFPFSSPSFSPPAFPSFPFSSPFPSSSPFPFPLIPSPSFPIPPPPPFPPPPTIPPPIPPPPPPFTPQPPPPQSPILPSPIPFLLHPNFPPASLFSILISFPSLFLLSHPSYPCPPPSPPQNPLSPSHPPASPSPYPLCFPSHPHPPFPPFPPHFPLSPSLSPLSPLSLCFHLTPPPLPPIHHPAFPSLFPHPPIPLPFPPISPISPPPHFPPPFSRRSRSRLTASKLSAAPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M051</accession>
    <name>A0A3R7M051_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013891</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002729">
        <property type="protein sequence ID" value="ROT68004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M051"/>
    <dbReference type="STRING" id="6689.A0A3R7M051"/>
    <dbReference type="OrthoDB" id="9049620at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052667">
        <property type="entry name" value="E3_ubiquitin-ligase_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47156:SF10">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM-21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47156">
        <property type="entry name" value="PROTEIN CBG20824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="135"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="331"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="417"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="467"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="484"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="509"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="632"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="641" mass="72321" checksum="DEB12B81DC8090E1" modified="2019-04-10" version="1">MKQVVEGLTLMLNYQSQNGRVPPSAPPSVPMAPGGPTLAYSTVPGNYNPGTQPGIQAKSDIRITMTQQDLLALITRALASEFMQSRDRDSSYTRDVNGAIARREGLEQEEPSTPPVPREQLERFSEDPLRDIMCCDVCGLHYNKDDRKPIILPDCGHTFCRRCLITASRNMELRCPTCRRGCRVPAEHLPPNYTVLSLVAEVNSTAAINGTPSATTNPSSMNDDEQMKYVLDLSRKLYEEEQDLLLAQQLQEEENAKAMMKGKKGKTSKLHAWEDVDQDDVDQPYPCRQNHGRDEGGQDAMNAYYSARRLMEEEDGELDTRVPYHQQHDSVLEDHESYRHDANPERGVELEDEGSGSDEDAQSWGESNSLRLYRSDVGRESPTPAESINDLQRETHSHRECMTDVGRELQTPGDSTYDVRREPHAPRESMDDIQRESHRPGESTYEQRESHAPRESMGDVHRESFTPGENISNAGRASCSSRDSINDAERESHTRDESLSPVCTPTENRNNKGREADSPKDNTGGARGTSYAKHSYKKPKEGSLELPPMEKDLEHYIDTHFYGKDGRKSKSASLDEETRSMLARALEREQQEREGSHKRKARRLLKEQEQIDLAIALSRSLQDASGNDDSDKDEKEKENEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M115</accession>
    <name>A0A3R7M115_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002628">
        <property type="protein sequence ID" value="ROT68831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M115"/>
    <dbReference type="STRING" id="6689.A0A3R7M115"/>
    <dbReference type="OrthoDB" id="6022711at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11324">
        <property type="entry name" value="IL16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11324:SF16">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="590"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="982"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1163"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="944"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1208" mass="131176" checksum="765D755239F2AF62" modified="2019-04-10" version="1">MRLFRRRHSDPRIVSSPSKDTVTAVPARVLETAANGTGTGTPPAAANATAGSTPPSSTNTTPKTPKKALATWGRRVGKKLEQLTRTPSKEKVSSNMFSRSSSTRSAGTGASPPSSGGASWGGSSVPGTPSPESRSVEARQLYRSCSASQLGTYLAGDDPTAGLDLGASPPSAAPYVPTKTVSCENIASLGGARASFPHAFLRSRPQAAGAQQAEAQETHTPITETPSRPPSKRLTTLRDSVCDEDTRELIRQKLRAVSEENCAASPAHRNLGGLKLRLHPIPTPLQPRSRSFSATAIIEADAAYAAAERPPTRQGARVHRADRFRARSEGRAAAVYLSSNESGYESDGARQESPKARAKKAESDADSGVSTESHSETNSDSGSLTGADSAGLDHYAKLDACAKLDDYAKPDRYAKAENYAKLEEFAREPFSHASADYADCSVTPKYSDDYTDYSRVLRHSRLERQSSGPTPSPGSKYNLTDEEKLVPGRSRGPRRLSDPPDLMCRRQRFLASQLERRTSPLSPLRGALSVFREASEDGERCAWWDESSTPLRGHLRAAALAHPVPESYSTAPLSLPVSLARSPTPRTFRLMRLVKDHTGELGIYITARRNARGATTGYVIAHIEKGGLTDRDGRFRVGDEIINVNGRRLRGVTLDEARHILRSTPKEVDIVIARDVDVHLHREYNGQCHAHDEKPSEAEAARRLSEACGELYTADRAFRQELLDADDVLGVRREHFVPYSDRSLPRRRGSYSDYDDYGDYSTLAPLEAYLPGYDPSRATVSVSGPVSVTVPLTDCPTSLPATLPPAAAEQSPATTFASSVPAACMGARDDYYDVHASRKSNLPRYVNGEARYCSSQDVRDAVDVRYSSASDVRLCADKTFSADIYKSKLIHVEPEDPQAETRQASMIPRLSTPHRTLAESRSSPATPSRKSPFGSRKYPPVTQRFASPQGYSKLPSPSKSEPRGLSSTLPRRPKSLSMSVQTVVFEKGRGRKSLGFSIVGGRDSPKGSMGIFVKTIFPNGQAAEENKLKNGECCRVSFRFSGAASLRRRLSSVGKQTKAKQKTRTLRWTCARPTGGDRRKIKGRGRGEGSGHGAALHCHPPEHVHRPAHPSSPPPFSLLLPSPFSLLLSSLPRLSPPRPSLFFVFFPPLSSRLAIKGLSFGQKRTSVPAPAPRASVFPRRRPSARSRSDRVSARGHVSVCEEIRNALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M228</accession>
    <name>A0A3R7M228_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative RNA 3'-terminal phosphate cyclase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003133">
        <property type="protein sequence ID" value="ROT65141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M228"/>
    <dbReference type="STRING" id="6689.A0A3R7M228"/>
    <dbReference type="OrthoDB" id="1911237at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF1">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="2">
        <location>
            <begin position="60"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="21806" checksum="57989FF613E58B3D" modified="2019-04-10" version="1" fragment="single">IDPSIDMIKLSLLPVLEKFLVTDEGLSLKMVKRGLPPKGDGVVTFTCPVRRTLKAFQWEECGKVKRIRGTVYTSRVAPTVGNRMLDAAKNEFTKFLTDVYFNVDNAKGVSPGYGLCCTARTNMGTMYCAEAMSNHQGEELEARLPEDVGREAAWRLMEEIFRGGCTDTLGQPLVLLFMALAPKDISKFVCGPLTPYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2N8</accession>
    <name>A0A3R7M2N8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002321">
        <property type="protein sequence ID" value="ROT71253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="422" mass="45643" checksum="DD23A1849C5E461C" modified="2019-04-10" version="1">MRNAAAPGNGAAGSALAGRRTCCPSSSLLLSFFSLSSPSFLFLSFFPSSSNSLLLLSLLLSFFPFSLLLSFFPFSLLFSFSLQFSPSSLSFSPSFFFLSFFPSSSNSLLLLPLLLSFFTFSLLFSFFLQFSPSSPSPSLLLYFFSPLFLLAPILSFFFPLLLLLLSFFPFSILLSFFLQFSPSSSPSLLLSLSLLFPSSSNFPPSYPSSLSFFFLSFLSFFLLLLLSPSSFSFFSPLFLLPPILSSSSLLLLSFFSLLFSFLLQFSLLSSSLSFSPSFLFLFLFPSSSNSLLLLSSPSLLLSLSFLPFLQFSPSYPLSXLPSPLLPVPPPVGFSPSPPPSLPGATPSGSSSSSPPPRPGASPSYPPPLPPVSSSPPPPSPLRYPRWVLPLPPPPPPFVSSLESDYRHTRASLGGRGCHGMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M386</accession>
    <name>A0A3R7M386_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cuticle protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002398">
        <property type="protein sequence ID" value="ROT70687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M386"/>
    <dbReference type="OrthoDB" id="6374545at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="22938" checksum="F06770EDA04AFED9" modified="2019-04-10" version="1">MEGVVTGRDERVLSLLAATCSAAPQLYQTVAGTVASPQWNLPAVMKIPEPGVNLGMAAPSLTVVEAAPVAVAPVAPLVKSAAIVAPAAPVAVAPVVKSAVPVTVVAAPEPLMAPEPPMPSLSVPHVGGQFHAQDEAGQYTFGHYGGPNTRVETRDSLGRTSGSFAYVDPEGDVQVRKYAAAPGSGFRVAASDLVVDTLAVAQVKSAHARAHQAVKSLTANSVVTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M887</accession>
    <name>A0A3R7M887_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012006</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002521">
        <property type="protein sequence ID" value="ROT69759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M887"/>
    <dbReference type="STRING" id="6689.A0A3R7M887"/>
    <dbReference type="OrthoDB" id="266334at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018770000" evidence="2">
        <location>
            <begin position="29"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="543" mass="60077" checksum="219EC7B0F24EF0DB" modified="2019-04-10" version="1">MTYAKGRAKCTLASKLLRFLFLQEVGVAIFERSGLPPVAGGLEVEKEVLSAIEARSSSVVNVTISPARVLDDGVHNVHRKVLAQHLKEKDDDHGRSGGGGGKLTHFLDAKEFFNSISSKNFTRIHSARAIQLVEGEARERDTGQRQGSGGGGGGGGGKKESEGGKEEKGREGTKPSDVRRKLGKGKDPEDVERGKAKEEKEGGKEETKNREGEGLKEKESESEDQGKESVEQQSEGAQTEDDDDGKGTKETSSKKEEEEGVSADADQDKEEPEETKEKKKKKQDKKPLDTPTPVPEERAESDDNEDKQAEEFTDTEPEEKEKNIGIVEEPEKADLSEEEKKKKKRKEEGREQEKEKGPGPEEQEAEAEAEKEELQDAVSDKKASEEEPSEATEEKEKTKDTAEEQKEEQKEEIPKESAKEEESQDKAEDAKEPEGEEKKQKETKAAKEKEIDEEKGERPTANITKADKETGEPEKAKKKQQAESAKIKKTKEGAEEGKADKKEEEKSPDTLETYSQFTQRVNAEKKNDVNANGHSGNGHKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M947</accession>
    <name>A0A3R7M947_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transaldolase</fullName>
            <ecNumber evidence="3 8">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_011274</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="3 8"/>
    <dbReference type="EMBL" id="QCYY01002425">
        <property type="protein sequence ID" value="ROT70445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M947"/>
    <dbReference type="STRING" id="6689.A0A3R7M947"/>
    <dbReference type="OrthoDB" id="2015515at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000088">
        <property type="entry name" value="Transaldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00492">
        <property type="entry name" value="Transaldolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009001">
        <property type="entry name" value="PRK12346.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT70445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="331" mass="36922" checksum="0C1C1F717C7ACA3F" modified="2019-04-10" version="1">MSESPTKKSKMATALDQLKEMTVVVADTGDFEAMKKYKPTDATTNPSLILQAANMEQYSPLIEQAVEYGKKTGSNSEEKLTAAMDKLFVLFGCEILKIVPGRVSIEVDARLSFDKAASVSKARKFISMFAEEGINKERILIKLASTWEGISAAKELEEEHGIHCNLTLLFSFAQAVACAEAGVTLISPFVGRILDWYVANTGQKTYEAHEDPGVKSVTKIYNYYKKFGYKTVVMGASFRNDGEIRELAGCDLLTISPKLLEQLQNSSEPVTQRLSEASAKKHDLEKVEMTEPKFRWEMNEDQMATDKLSEGIRKFAVDAIKLEKMLVEKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD35</accession>
    <name>A0A3R7MD35_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative discs large protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008377</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002055">
        <property type="protein sequence ID" value="ROT73193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MD35"/>
    <dbReference type="OrthoDB" id="10067129at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035331">
        <property type="term" value="P:negative regulation of hippo signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053004">
        <property type="entry name" value="MAGUK_Signaling_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46360">
        <property type="entry name" value="DISKS LARGE HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46360:SF1">
        <property type="entry name" value="DISKS LARGE HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="858"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="953"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1029"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1162"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1266"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1320"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="352"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="495"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="716"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1166"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1281"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1327"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1350"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1378" mass="157286" checksum="051C06938AC7E33A" modified="2019-04-10" version="1">MIVTTDRDIMKKELKKVTRERDDAVSRLNAVSQSDQPANYGTLGKHGVSVSDKSLSTPRDYESIKLQCEKAMAEVQGLLKQNVDLTRKYENCMKEVDYYKKQERAAYTALQNLRMQYEEVVAEKQKLEREVTSLQTIMEDDRKEIADLRRQQQEAMSQEGSGEAINQLYMTTMRKYEAIKDEYDSIRKRYSDLVASHSNNISKLELTQEEVSRLKKQYDEVLRECNEAVREKNCLKQQCTKAITEWDSALREKNKLQEELLKIREKYDEMMKEMNTHLMQRQHLNKDLKRLQIVTTDRDIMKKELKKVTRERDDAVSRLNAVSQSDQPANYGTLGKHGVSVSDKSLSTPRDYESIKLQCEKAMAEVQGLLKQNVDLTRKYENCMKEVDYYKKQERAAYTALQNLRMQYEEVVAEKQKLEREVTSLQTIMEDDRKEIADLRRQQQEAMSQEGSGEAINQLYMTTMRKYEAIKDEYDSIRKRYSDLVASHSNNISKLELTQEEVSRLKKQYDEVLRECNEAVREKNCLKQQCTKAITEWDSALREKNKLQEELLKIREKYDEMMKEMNTHLMQRQHLNKDLKRLQEERNAAMQEYTLVMSERDTVHKEMDKLQEELSQASKKIKTIEQSTNDSTKERESLLLQIEMLKREIAASLHDRDKAIKECNDLRERFGAKEDTNKEWEGSYKDHDNYKQEREMTLKEGPDLDSSSHNMYSKAQKERLDNLDQANQEIDRLRKTIEKLQSELQEAQQEAEVSKRRRDWAFSERDKIVQERESIRAHCDKLRRERDRAVSELAEALRDSDDMKKQRNEASKELKELKERLEAEQEKAAVVRQLAAHNHSRDSAIDTDMQEWETDILHLPIGVVSERDVGFVVAGGADDPHYGGNDGAIYVTHIAKDGPFEGKLRLHDQIINVNGVDCQRVHRSSVYAAVVNGGGWVQMTVRRRRSGGRSLHTVHLHCPHTAHHGLTLHTGVYIANILPGSPAARESNLAVGDRVLNINGKPVDNIGSCEEAQCLLDAAGEVVQLTTLKSHGSSSLSDPLSSSSSGHNITEDDKSTSSSRPYSSPTSPSKETGVSPGRSGSRELVKKLMPGSGGSHSEDNSCKRYGSSEKSGSNGGTSTTKRSKKREKDKSGGTWPKYRGGGSGKVGKAELEYYVKKNILKYPPSDSESIDNSLQISQPPVYGTRPSPLHHDRTPNSRIPHPHSGLYSPPNPPLRSPQGFGPYPHLSHFSLSHPHQYPHSSVGSSISAVSPRYSSPPTLPVVPSHYLSQSRSGDSIFPSGLERDPRDGRGYYESRQASSPTPVGMIGTVSGGVFYHSPSPSLELPGHHKPRTLHHLHPYRPTSDDHPLLPHHSCPPSYHDSQRFTGTMPRKKEDERIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEM2</accession>
    <name>A0A3R7MEM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Estrogen sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEM2"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="16296" checksum="297990F3CBA798E3" modified="2019-04-10" version="1">MKFLSGHEAKAIEGEEWKRQKSHWLGYADGLVRFSPGGWVLPTPFTKFADKYYDFKFRSTDVLVHTWAKCGTTWTQEIVWTMRNNPDLNHPMAGISVNARAPFLEFDMFMAIPRRNQTTTSSRLSTDSAPERTRRMACSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHH6</accession>
    <name>A0A3R7MHH6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001622">
        <property type="protein sequence ID" value="ROT76687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHH6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT76687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="874" mass="97804" checksum="7F48700C46E5D21B" modified="2019-04-10" version="1">MAGGGREEELELLLGKLQSFGPGNGQGDPDAAKDVIVDIAELLAVDLTPAQYGMCRILKQKNTRTQVIALRAPLQVIPSSRLFRSPLKSYFKFQGCSELPRQVLFQVQRLFRASHFKVYFKFEAVLRAAHSQVISSSRLFPRSQFISSLQGLFRAPPSSYFSLKLFELPTSKFISSSPKGWVRAPTPVIFKFKAFRAPTQFISIPRLFELPTPSISVQGCSELPRQVYFKVQPVLELPLKFIFKFKGLFRAPTSKFISSSRLFRAPTSSFQVQGIPLVYKFKAVPSSHFKFISSSRLFRAPTFQVYFKFKFFQELHFKFISSSRLFRAPTSVYFKFKAVPSSHSKFIFKFKAELFYFKFKAVPSSHSHCSSHSLFQVQGCSELPLQVYSKFKAVSELPLKFISSSRLFRAPTSSLFSSSRLFRAPTPSLFSSSRLFRAPTVQVHVPKLPLQVYFQVQAVPSSHFKFISSLKALFELLKFISSFKVFRSHSKLFQVQAVRAPTSSVVPSSKFISSSRQVKFISSSKAVPSSPRSSLFSSSRLFRAPTQVYFKFKAVPSSHSKFISSSWLFRAPTPSLFKFEAVPSSHSKFISSSSCSELPLKFISSSRLFRAPTSSLFQVQGCSELPTSSLFKFKAVPSSHCTLFPSQGCSELPLSSLFQVQCCSELPLQVYFKFEAVPSFFCKGLAERSKLQVRVSSKVDESIYSKLKFVLQALRPSLLVCSKLYAQVCWFVPSSTPKSAGLFQALRPSLLFVPSSTPKSACLFQALRPSLLVCPSSTQVCCCPSLLVCSKLYAQVCCKLSPKLYGFQALRPSLLVCSKLYAQVCWFVPSSTPSKLYAQVLLVIPSSTPKSAGCSKLYAQVCFFIPSSTPSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI64</accession>
    <name>A0A3R7MI64_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003728">
        <property type="protein sequence ID" value="ROT62329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1370" mass="149711" checksum="F2D6D841D33131A8" modified="2019-04-10" version="1">MAAQRGSRWFRLLVVGLQACGIFVHTWPQEGSTPRSTCSVLLCLWALFIRLWMAGSLFVYGAEKIESDKAGNIGDIAVITTMVSAASAYTIGPVFLLAKSKGFALLIGQLQDVIGTQTARLARKIVYLLVFYVVICATFTGSMFFSSTIDSMDLSLAIPVAAFIVVVTMSVSLVIEVFHVIVELLAHEILNTSLQTKLLLIPRHLDQDSLDSPAPIGDFQLKSCGESDVLKEDMAIQLCIRLSEGILRRLERKIYQVTLLRERVVKLFFPTLSLLFLSFTTSGITSLFLILTDLEHAKWIGVYSFISLTHFFRICTTGEAFTKKVWLLAFSCRRSLDQKGLAPRFLLPAKPSPGRSGSSLSLRRSLLLLAFSCRRSLRQEGLAPRFLLPAKPSPERSGSSLLCRQSLRQKVWESLEGLAPRFSCRRSLRQEGLAPRFLLPAKPSPGSTGKGRSGSSLLLPAAFEGRSGSSLSLAAALAPAFSCGGTCRSLLSLSSLLCSPAKLRQEGLPRFLLPPKPSPGRSGSSLSLAASLRQNLAPRFLLPAKPSPRRSGSSLSLAGKAFARKVWLLAFSCRRSLRQEGLLLASLREAFAKKVWLLAFSCRQSLRQEGLAPRFSLPAKPSPGRSGSSLSLAGEAFAKEGLAPRFLLPAKPSPEGLAPRFLLPAKPSKVWLLAFSCRRSLRQEGLAPRFLLPAKPSPRRSGSSLSLAGEAFWLLAFSFAKGSRRRSLRQEGLAPRFLLPAKPSPKGLAPRFSCREAFALAPRFSCRRSLRHWLLASSQEGLAPRFLLPAKPSPRRSGSSLFSCRQSLRQEGLAPRFLLPAKPSQEGLAPRFLLPAKPSPRRSGSSLSLAGEAFAKKVWLLAFSCRRSLRQERSGFLAFSCRRSLRQEGLAPRFLLPAKPSPGRSGSSLSLAGEAFAKKVWLLAFSCRQKPSPGKVWLLAFSCRRSLRQEGLAPRFLLPAKPSPGRSGSSLSLAGKTFAKKVWLLAFSCRRSLRQEGLAPRFLLPAKPSQEGLAPRFLLPAKPSPRRSGSSLLLPASLRQEGLAPRFLLPAKPSPRRSGSSLSLAGKAFAKKVWLLAFSCRRSLRQEGLAPRFLLPAKPSPGRSGSSLSLAGEAFARRSGFLAFSCGKASPKVWLSFSCRRSLSGSSLSLPAKPFWLLAFSCRRSLRQEGLAPRFLLPAKPSPRRSGSSLSLAGKAFAKKVWLLAFSCRRSLRQEGLAPRFLLPASLRQEGLAPRFLLPAKPSPGRSGSSLSLAGEAFAKKVWLLAFLPAKPSPRRSGSSLSLAGEAFAKKVWLLAFSCRRSLRQEGLAPRFLLPAKPSQGRSGPRFLLAFALAPRFSCRRSLLWLLAFSCRRSLRQKVWLLAFLPGLRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMB9</accession>
    <name>A0A3R7MMB9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Slit 2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016582</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003084">
        <property type="protein sequence ID" value="ROT65441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMB9"/>
    <dbReference type="STRING" id="6689.A0A3R7MMB9"/>
    <dbReference type="OrthoDB" id="6357701at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000082">
        <property type="entry name" value="Leucine-rich repeat-containing 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF163">
        <property type="entry name" value="KEKKON4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="8">
        <location>
            <begin position="225"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="514"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="457"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="550" mass="62681" checksum="D91AC57F2A7F3B2B" modified="2019-04-10" version="1">MVVCQNANFIDIPRGLESTTQVLDLRHNNLRILPRDSFAYSGLLNLQKLWLNFCNIMWVEKGAFRKLTHVKELDLSNNFLRDVPSGALADIASLRELRLAHNHLTVLSAAAFLFSLDLVELDISYNKIEKIEERALRVLGNLEILNVAGNRITFLNSTELRPLQVLRVIRVDDNPWYCDCRLRQLSHWMREQKLTASTPPSCSHPSWLYGLDWQTLDTKHFLCAPHAMAVAPRILATDRDNVTLMCKVEAEVEVIISWLADEIPIRNTNMTHRYKVKQSGDPDRQLYVSNFTILSVVKEDQGVYRCLAENRAGTSVCDIILQVSHEVAEVRSENVEQIFMRRGLLGAVSIFLFLVFFLCSAMYCKAKDPRLQVSEEDNLRTTKLTKNLHEKLGQHNVGHDSKSNTQTHDAQSWVISDSPCEKVQTSDLSTESRQDLATPDNGSPKQPLFIGTTTSCVEKKKQEETDIQTNKEDDMYPKTFSEENVFSAEFNRPPSHSSLGNISHFPDLLDLPQSRLSDLAAPQQYEPFQRPQEDLSLSTHRPYSSSSRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPQ8</accession>
    <name>A0A3R7MPQ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="4 13">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_024205</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="4 13"/>
    <dbReference type="EMBL" id="QCYY01000795">
        <property type="protein sequence ID" value="ROT82633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPQ8"/>
    <dbReference type="STRING" id="6689.A0A3R7MPQ8"/>
    <dbReference type="OrthoDB" id="1621027at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12173">
        <property type="entry name" value="PGDH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000021">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938:SF22">
        <property type="entry name" value="D-3-PHOSPHOGLYCERATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42938">
        <property type="entry name" value="FORMATE DEHYDROGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="Serine metabolism enzymes domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase catalytic" evidence="14">
        <location>
            <begin position="8"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding" evidence="15">
        <location>
            <begin position="111"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="D-3-phosphoglycerate dehydrogenase ASB" evidence="16">
        <location>
            <begin position="329"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF19304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT82633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="533" mass="56121" checksum="E7749C08C0C87F6C" modified="2019-04-10" version="1">MTAKIEKVLLLDGVDSVCGEILQKAGIKVTVHAKLSKEQLAEELKSHDGMVVRSATKVTSDVLAAAPALKIVGRAGTGVDNIDVEAATRRGVIVMNTPGGNTLSAAEHTCAMVCSLSRSVPQACAALKAGKWDRKLYMGSELYGKTLAIVGLGRIGREVAKRMQSFGMTTIGYDPMIPAHVTAEWGVESMSLEELWPRADYITVHTPLLPHTRNLIGSEVLSKCKRGVRIVNVARGGIVDEAALLVALEDGRCGGAGLDVFLEEPPTDLTLCQHPKVICTPHLGANTKEAQRRVACEIAQQMVDMMQGKPLVGVINAPALTNATSDACRPWIELAQSLGCLANRISQPTDTPSLSISLHLYGPGVSKMKTFLGSAVLVGLLKEMASSDVNLVNAPLMAQEMGVTVTVDDHPDICPSIAAAGPEAVEVKVTRGLNTHTLLGNVSGGQATLYGLDGCVWEAGLTLGRNMLFFTASPGTSPLAAIATQLASLQASLTSLSSSVPNTKEGWHVARTQAAVDFQSAIPNARLVAQVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MRM4</accession>
    <name>A0A3R7MRM4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000587">
        <property type="protein sequence ID" value="ROT84154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MRM4"/>
    <dbReference type="STRING" id="6689.A0A3R7MRM4"/>
    <dbReference type="OrthoDB" id="6352234at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="27"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="133" mass="15376" checksum="5D7D6BA68F40FFAE" modified="2019-04-10" version="1">MSVSRCLPLLRPHLDRPRRGLGHLDPDSKKGIPVKTVPIATILRALDVTQIDFFSLDIEGAELKVLATFPWDEVKIRLMCIEVNHVGKERVSSFMEKRGYMYVGTWHIDAWYGWKDLLKETINVEEYPKKLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N011</accession>
    <name>A0A3R7N011_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">NADPH:adrenodoxin oxidoreductase, mitochondrial</fullName>
            <ecNumber evidence="5 16">1.18.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C7M84_007956</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>2 reduced [adrenodoxin] + NADP(+) + H(+) = 2 oxidized [adrenodoxin] + NADPH</text>
            <dbReference type="Rhea" id="RHEA:42312"/>
            <dbReference type="Rhea" id="RHEA-COMP:9998"/>
            <dbReference type="Rhea" id="RHEA-COMP:9999"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Steroid metabolism; cholesterol metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 16">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.6" evidence="5 16"/>
    <dbReference type="EMBL" id="QCYY01002014">
        <property type="protein sequence ID" value="ROT73630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N011"/>
    <dbReference type="STRING" id="6689.A0A3R7N011"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="UniPathway" id="UPA00296"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000036">
        <property type="entry name" value="NADPH:adrenodoxin oxidoreductase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055275">
        <property type="entry name" value="Ferredox_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021163">
        <property type="entry name" value="Ferredox_Rdtase_adrenod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000362">
        <property type="entry name" value="FNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 16 17" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14 16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 16 18" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="19">
        <location>
            <begin position="28"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="173"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="394"/>
            <end position="396"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR000362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ROT73630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="481" mass="52254" checksum="892F4A3D487EA0EC" modified="2019-04-10" version="1">MLLRLGISRWAACRLSTSAATSTAHVPKVCIVGSGPAGFYAAQQIIKSHEAAEVDIYEKLPVPFGLVRYGVAPDHPEVKNCINTFTQTASKNRVTFLGNIDIGSDVTFSQLRQAYHAIILAYGNAKDRKLDIPGEELSGVLSARQFVGWYNGLPEDADLKVNLDVESVAVVGQGNVALDVARILLTPMDMLRKTDIPENVLACLDKSQVKYVTLIGRRGPQNVAFTIKELREMVNLPGCRPNLIAGDYQHLKDLIPSLPRPRKRLLELLAKTALDTPAPALASAWASAQKEWRLRFLLSPVEVLAGADGQTVSGLKLAHNRLEGDGDNQRAVQTEETESLECGLILRSIGYKGVPIDSSLPFDHRTGTIANDNGRVKGHNGVYVSGWIGTGPVGVILSTMTSGFTSGKMLVADINSGQVDVSSARGGKEEVLDILSKKDKKPVTFSDWNRLDKFETEIGAKLGKPREKVTNIQKMIDISHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N0Y7</accession>
    <name>A0A3R7N0Y7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001910">
        <property type="protein sequence ID" value="ROT74318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N0Y7"/>
    <dbReference type="OrthoDB" id="6360260at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018628749" evidence="1">
        <location>
            <begin position="16"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="219" mass="23666" checksum="E9CC0E6D5D577108" modified="2019-04-10" version="1">MKALIAVLLVACVAAEQKREAEPSYGHGVGLSFPHGVVSGRQYGVGYGHAAIAHHPYGGRSFVQSYSHNLHKREAEPGYSHPAYGYGYGHSHAFAPAIAHHPYGGRSFVQSYSHNLHKREAEPSFVLPSYGYGYGGGIGYGIGHSLGYGPAVAYHPYGGLSYTRSYNHVLHKRDADPSYGHTHGLTGSVYGYASSVTHPGYGYSYQQRHGVVPAHYALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N1A2</accession>
    <name>A0A3R7N1A2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative organic cation transporter protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006911</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001877">
        <property type="protein sequence ID" value="ROT74576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N1A2"/>
    <dbReference type="OrthoDB" id="6484641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="46480" checksum="EA61957D9925410E" modified="2019-04-10" version="1">MFGVTIGAPFNGVLADRYGRKMTVAAGSIAYSALAIGSCWIPNLSALLLSRFLMGAVHPTIQKTGYILGMEVADPKWRTHVGIALFMPWGFGIIAWGGIAYLVREWRMLQLTVSLLCLVFLPTLWFMDESPRWLAVRGQHRRALRVLQRAARWNGVALPPEDELLLLLKDGVKDEAMERPHQDTHAHSPKGAFRRHLDEAFILFRTPRLRTITLSLYTNYLLVGAVYFGLSLSGGDLSSDPFLYMVLTGVVELPAYTLVIPLVARYGRRAPVVAFFFLTAAALLVLPFVPAGSMVLALIGKMSIASAFQVLDLYSSELFPTEVRTRGMSTAHVMSRVGSTCSPYIIDYLPPCITRPNPKTSPLLARAPCTRGRRQQCSGGVGARGTGHAPLPETLHVALPDTIEHLEEREIRTRRLAWLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N8K0</accession>
    <name>A0A3R7N8K0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001146">
        <property type="protein sequence ID" value="ROT80169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N8K0"/>
    <dbReference type="OrthoDB" id="10072532at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="204" mass="21922" checksum="3AD5B4818FC5A8BE" modified="2019-04-10" version="1" fragment="single">LSGQKQQIKLTLKGSAMRRLDKPVLPQEDDSGESDTDGKVIRKRKPDSPPPEPPPQKVVVRSPPAPIPAAPPQAKKPQANRREELLKQLLRDLEQVHCSRREAEEEQQEEGASLRAALADQKLSSRHQTLQPALREAEQGQGGCQVPVSSLTGPDSSSLASPSCPLPAPFALTPFSQLSCAWSGTCSSSKREGGGGVQPSEEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NAI8</accession>
    <name>A0A3R7NAI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024986</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000910">
        <property type="protein sequence ID" value="ROT81853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NAI8"/>
    <dbReference type="STRING" id="6689.A0A3R7NAI8"/>
    <dbReference type="OrthoDB" id="6393648at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="246"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="330"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT81853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="38502" checksum="E8042D1BB8EC6CA5" modified="2019-04-10" version="1">MAAQALTRPRGAPESESLTAEQQASSRYDWPGRPREDDLSRPSRLSCSLGDEGGEGAWPEDLRGGGGSFRQDREAAARRCRRRPRRIVKMLILGGDVNGKNEKGATPLHRAAYKGHTSVVTALVTRGATVNEIANLGFTPLHCAAHQGHEAAAEELIVKGADVNAKKMNGPSLQYGPPLTAPFPCSWTWPERATPRPCRRPRLLAPRATKDFFAEKPLHVAAEEGHDEVAKMLVSMGANVNDKNDEGCTPLHVAAEEGHEAMVQELAVRGADANAKDDAGYTPLHLAAQEGQVSAIEELIAKGAEADAKDDAGYTPLHLAAQEGRGGGGDARRQRRPSERGGERGNPFYGTVTEPQILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NDV5</accession>
    <name>A0A3R7NDV5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7805 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022281</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000531">
        <property type="protein sequence ID" value="ROT84521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NDV5"/>
    <dbReference type="OrthoDB" id="10037824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056707">
        <property type="entry name" value="DUF7805"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF3">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25090">
        <property type="entry name" value="DUF7805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7805" evidence="3">
        <location>
            <begin position="171"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="49708" checksum="5595A72D580DE222" modified="2019-04-10" version="1">MDFILRYEFVNTAPGYQPTNGSECDFEAISDGYSLRTGRVFSPRTSVLYGRWGRKKLSCQYRLTAHSDEVVRVTITKFHSVSRSCVTTTNNFTKGYDCDNLSGQTASLVLSEYPWQDIEVPRLCTCDYSAIPIEYESKSQEVRLRFEVDNMDDNHDYMDFMFEAQYEFIKKSSCKKVQRLQGTNGQIVFQRANKTEDKPCDSYPWLLQTSDAQKSIYFRIRGYDHIDKNCSTSTRLLVFKVGRLRPVGVLCPDPTSKNVVELFSFAWQGSGTLVEQSTDKLVLEVSGRDPTRDSGPHTLSWLQVSPARQYDWSAEGIVRGCQQECPELGVCISEDLWCDGIHHCPSGHDELIAHCFFLSVPWAYIGVGSALSILFLVGVTVYGAARLRASDHKTHQHQPIPTLPTASESLFSSDKDAAERDGGVTSAYSLDYSEVDYVTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NP48</accession>
    <name>A0A3R7NP48_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_019121</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003506">
        <property type="protein sequence ID" value="ROT63000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NP48"/>
    <dbReference type="STRING" id="6689.A0A3R7NP48"/>
    <dbReference type="OrthoDB" id="6347820at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050780">
        <property type="entry name" value="Mucin_vWF_Thrombospondin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014853">
        <property type="entry name" value="VWF/SSPO/ZAN-like_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001846">
        <property type="entry name" value="VWF_type-D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11339:SF272">
        <property type="entry name" value="BMP-BINDING ENDOTHELIAL REGULATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11339">
        <property type="entry name" value="EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08742">
        <property type="entry name" value="C8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00094">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00832">
        <property type="entry name" value="C8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00216">
        <property type="entry name" value="VWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50923">
        <property type="entry name" value="SUSHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51233">
        <property type="entry name" value="VWFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0768">Sushi</keyword>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="460"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Sushi" evidence="7">
        <location>
            <begin position="488"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="590"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="VWFD" evidence="8">
        <location>
            <begin position="733"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="612"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT63000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1031" mass="110054" checksum="98F1CCBEA293E592" modified="2019-04-10" version="1">MSLAVEESHSPIQLRVDTEGNIATTAPLGDVKPFACLVEAGVPRGSLTTAVSTQYPFDRNPMFRASSSYNSRKGGPRTLSRSTDRSFSRFGGGPEAFLEAATTERIEAEEDVMGFKFSGSANFGASRPSGGGRKGGPSKGGSKGGNPFATFDRESAPGFPPIRNIGGAPGFSGASGPGFSGASGPGFSGASGPGFSGASGPGFSGANGPGFSGASGPGFSASSSSATFGGSLGAPFNGPAAPAYSSPPGTFSGSLTQGGAKFGASFNPGFSGSTNYFGGNAGGAFPAPKTPFSAAFPGVSGNINFDPNGGNIQFPPPSGQFPPSSIFPSMTEEEGGPIVFPQGPGEGAAGLNLPFTIDDELAALLFGMQEATTANGRQDEADEEVEPPILVRRPEVKQGCNSKPSAPANGRTDCSTYAGCRSVCNPNYQFPSGERRLYLMCDNGEWKVTGSVWETLPDCEPRCSPPCENNGICLAPSVCQCPDNWEGDQCQIPKAPPAKKCSNKPPTPKNSRIFCSKDECSARCHEGYHFAEGTARLSFQCEDGEWVIQDPRWTETPDCERKSGLLWLGCGWVDEVVAGCVVAGVWMRGWRAACDPACENGGRCIAPDMCQCTVDFRGELCQYRKYRLPLGCKSVTTSNCDPKKLGFKGGYNCSGEGMDFGCAFWCPPEADFEFPAEDFYKCDYATGLWSPSPIPNCDYGFLVVTPGAQDISTGTYPPGFVFTTTEYIRKSPGVCFTWSGSHYKSFDGRVYSFESSCPFTLLQDSTHGTFSVNLKSKDDCTGSSCSKAIHLFLDDEEYVLQNTGEGEGRGSFFLECYLALSESGQPSLEYHETNLAIPGQMNGVVSERVAHYVLLKVDAIGLTLKWDMKNTVITEVNELLWNRTSGLCGRRDGNKENDWGYSDGRTEDNLSSFLQAWQSKTIGDQCLGQPMIKNPCGRRPVSSQATDFCSRLRDDPKFEPCRQVVDVDPFVSACKWDYCGCESDDREGCACESFSAFFRECTSQGVDLPEGWRAPGLCRKTRGWTLRVGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NQ54</accession>
    <name>A0A3R7NQ54_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative sarcosine dehydrogenase, mitochondrial isoform 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003380">
        <property type="protein sequence ID" value="ROT63786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NQ54"/>
    <dbReference type="STRING" id="6689.A0A3R7NQ54"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.110:FF:000008">
        <property type="entry name" value="Sarcosine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.120:FF:000023">
        <property type="entry name" value="Sarcosine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000769">
        <property type="entry name" value="Sarcosine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000004">
        <property type="entry name" value="Sarcosine dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032503">
        <property type="entry name" value="FAO_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF11">
        <property type="entry name" value="SARCOSINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16350">
        <property type="entry name" value="FAO_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase central" evidence="5">
        <location>
            <begin position="220"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="GCVT N-terminal" evidence="3">
        <location>
            <begin position="278"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="4">
        <location>
            <begin position="611"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="711" mass="78989" checksum="FFC4ECBDCC0786C4" modified="2019-04-10" version="1">MDPAGLCTALTRAATRAGARVVEKCPVTDIRTVPTLLGGRKVSEVHTPFGVIKTNNVINATGCWANDIANMVGVEVPLAPMKHAYVVTERIPGIENMPNVRDHDASVYLRLQGDALSVGGYENNPVFLDKVEREFSFGLYELDWDIFMAHIEGAVNRVPVLENTGIKSTVCGPESFTPDHKPVMGEDPTVEGFFHCCGFNSAGMMLGGGCGDQIAKWVVHGRPEIDMFGYDIRRYHTPLNVNKSWVLERSHESYAKNYSIVFPHDEPLAGRNQRQSPLHNVLEDLGCVFQERHGWERPGWYNTVPAPTQPYDWYGFYGSELSSDTRYKTMLTADYTFDFPHHHDLIQKECLACRNAAAIFDMSYFGKFYLTGPDAQKAADWLFSADVARDPGSTVYTCMLNRRGGIEADLTVSVCDSGEGSPCDPKFEGRGFYLAAGGAAALQNLAHVTKEIRSHKWNVQILDHTDDMAMLSIQGPNSRAILQQLSDADFSDATFPFSSHKVITVAGHKARALRLSFVGEMGWELHIPNESAVAVYKAVMATGEPLGLVNSGYRAIDSLSCEKGYRHWHADVRPDDTPLEAGLAFTCKLKTDTNFLGRQAIERQKAEGIRKKLVTLTLKDSSKPLWGLEGIWRNSEVLGYVRRAEYAFYLGRAIAYGYVERPDGEQITNDFLKSGTWQLEAMGTMLDASLHVQSPFDPKNLRVKGLYSEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRC6</accession>
    <name>A0A3R7NRC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative amiloride-sensitive sodium channel subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_017433</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003221">
        <property type="protein sequence ID" value="ROT64630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRC6"/>
    <dbReference type="STRING" id="6689.A0A3R7NRC6"/>
    <dbReference type="OrthoDB" id="6382381at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF248">
        <property type="entry name" value="PICKPOCKET 17, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 15" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT64630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="570" mass="64302" checksum="ADCB58E5326F9D9B" modified="2019-04-10" version="1">MIVKTTASSNEGVLSTTVTFTRTTNHFHHFTVCLVYHHSLTLHSGVSEATTTTSSNEVTSQVCLSEVSTTPSSDVTSHFIRPLRRKKREDRRPPPRDDDHEEYEDLFQNYQEMAPSERHDLQMNFLSLYMDMPPAIKRNIGYSFDELIKDCDFLGRKCYNESQFHHHLSPTYGNCYIFNGAGGVYTSLTGPTYSLSLVVDIWEKTYLPRRLTKKVGARVAVHRPKTLPLLDDDAIDVGPKLASSIAIKELNLHRLEKPYEANCTGSWETTKYQYINRTYANVYTITDCLRMCLQRLFVDRCSCFHALYPDNFVFDGKKYIRFFSTCNLTSTNPNSACVEKSLKLYSTNPGAANCGCNVACNETQYPSALSMANWPPEASEKDVKADYGKEETDDMMRVDVFFHTLNVDDVTPVESMRYEHRGIERALISKVENVWGLVSSLGGALSLYMGISVFLLVEVLEFLIYLVVNSCMYVVGGYETQTEVSPGHSAPISPLRQISSKFSSRAAVNTPSDAPTLFRDANHTCTVLWPLIETLLPKIYRSLAGVNSSRLPIEGVMTRGQHRSPILQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PC24</accession>
    <name>A0A3R7PC24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000967">
        <property type="protein sequence ID" value="ROT81481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PC24"/>
    <dbReference type="STRING" id="6689.A0A3R7PC24"/>
    <dbReference type="OrthoDB" id="10620640at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="24216" checksum="3FFCAF1C799EB0A5" modified="2019-04-10" version="1">MSRRNVLATAPRNLESGGRISSLAHFGAASLASALTLARTHVSPASSLSRRMSSGSRRATRHQQEKDDEVPQWIPGLGSDKPKPRTLGTSFFGYVPDAFVEKTPYLPSERTADSAKKQAELEKSAGQRSESASEISEQDATSQRDMDASSDEGVVTEEVIVPRRVMSSAAEPWNTDVLDGVREVACCLVNNALSSASSFVDAKDPSRCNRGQRISVMVRWIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIH6</accession>
    <name>A0A3R7PIH6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014239</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002784">
        <property type="protein sequence ID" value="ROT67655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIH6"/>
    <dbReference type="OrthoDB" id="6347579at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45823">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45823:SF1">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13975">
        <property type="entry name" value="gag-asp_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="431"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="793" mass="88883" checksum="DFB6532AC134A700" modified="2019-04-10" version="1">MADNMADDRTEGTEEMAGEQVVPTRQAAGTPPPSSPVVTGVDLDTIIRLLSQTRETIERQTAQATEERAQQAAQQLQSMSELKYTLKAELDAMETRVRDYTNDVCARVKWEVKREVEEPLQAMKHQLAAVTRDVEAYRQMMALSAVLTSLQGYVLVEGNAAPWALREQNLTEVASTSWSQQNMVEEEGPSAPPLFPSPPPNTKCIPKDQLGITDVAWAAVIDKRLAEYDGKVSWNAFQAQFETVARRQGWNDEEKAYKLVISLKGAAVEVLEHLTAAQMRSYACVVRALQRRFGCRQQPEVYCAQLKTRTRRRDESLPQLAQDIEVLVGGAYPMATEETIDMLAKDSFVDALNDKQLQVHVKQAGPHNIQEALVRAAEFEAFLLTTMPSYSMHRYRGEMTISPRHIHVRRTMAKRSPPSRRTSPDGFRGICWRCGLKGHRRNECTSGGANSSRSMEDHRRPIFQPCCRACGDEDLRSARDWNREYGPAGRRAAAQQDAMSPQYTRYQQVVAPIAMRVAGKINRCPVEMVVDTGSELTFIRKDLIVSCGVPKAGQKLCGVTGDCIPMRGPVWVSLNVGDMIERLPVFVAEMEDPCLLGLDYLARVEACVDLQRRRMTVRGHEVPLILGEHALVAQTHISHYHFISSCNTRHPTVTRKGGQASSATGSNTSHLEDLVQRSIKHLTMVLVTKKDGSKRFCVDYRALNAVTVIDAYPLPRIDDTLDALSKGLWHFNVMPFGLWNAPGCFELLMEQVLEGLQWKVALVYLDDVLVFGNTFEEELEYLTEVLCRFKAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN64</accession>
    <name>A0A3R7PN64_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_009753</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PN64"/>
    <dbReference type="STRING" id="6689.A0A3R7PN64"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="208"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="97"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT71869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="674" mass="73218" checksum="ECCC838CCBCD9E26" modified="2019-04-10" version="1">MGSQSLWQLRLESKSEYFSTPRDEVRRRGGGRVLGPRSLFWKLVVPPLVISECVDLVDLGEKWFCISLSLYLSSWLSKRRHASFEDIRRSRNRCCRRHDLDRPDQPGIRRHPRRRSDRSRAPPPPPVGEGGPAEDKTGSTDAKRPPPSGRISPSDLKAKGKQFDLVKELITGEDLVKAVGGSGPAWKADEGQRNGDDTGQPAPDAGPALGTQALGVVMASLTHLAIGTIVGLPGVTLPQLTDPNTEDIFLDTAQVALFGSLVHIGAIVGSLVGGALNLRLGQRVTLLIAMPLSLALWLALAFSPAVWMVQVARTLLGVAQGLAGAAANNYVVEVAHTSVRGRFAGFVDTARQLGFLFAYVVGSTGLSWRHVSLVCGFVTAIPPFIGLLFLPNSPRWLVTRGRLEEAHKALKFYRGPRYDVSSELSAITEQIDRTSSSTMGTKDQLRLLREPSVSRRLVLLTFLMFILQFTGNITIATYVVTILKSSNTGVDAYTSAMLVGGIRVVGTVAFLLLVDRVGRKAIVLATCVACSVCLTVFGVYFYLQNQSADLSHLTWLPLTVLLLYMPLVCALEAATCLLRGELLPTNVRAVGAALMYIFFFLGMFATAHSFPASVSTIGEHGVFWLYAGSCLLMAAVVGLSVPETRGLSLEQIDDFFRAQRKRTDASQIEKDSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PP91</accession>
    <name>A0A3R7PP91_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002097">
        <property type="protein sequence ID" value="ROT72862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PP91"/>
    <dbReference type="OrthoDB" id="10565666at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="175" mass="19899" checksum="E595C267BFA5D34D" modified="2019-04-10" version="1">MMDGWCEWLLHDGSTDRNRDTRVGEGSCPTRSNCLPSRFTVASDEQRTQGQVSILAYICATCPDPVAVVRVHLTFDQDFAMRVQYIVFLALMATASAKAWYLVSFADNNLEFKPVSNPWQPAVADFENPSKKSQTTKTDEGDVQKRREEMRRLLHRFDWSDENSMSDEDSNSYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPC4</accession>
    <name>A0A3R7PPC4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002887</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001387">
        <property type="protein sequence ID" value="ROT78409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPC4"/>
    <dbReference type="STRING" id="6689.A0A3R7PPC4"/>
    <dbReference type="OrthoDB" id="6358729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF174">
        <property type="entry name" value="TYRAMINE_OCTOPAMINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="82"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT78409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="163" mass="17013" checksum="FF55FAB57281E5BF" modified="2019-04-10" version="1">MTWAAQAGDPAAATASSAFLSTSPSSFSGGDLSVVATMVGNGSLLDLGDNCSEPLGHVDWGDVGMLTSLTILVVINALVVAGNCLVILAVFLSSKLRTVTNLFIVSLAVADLLLGMAVLPFSVTVEVFDTWLFGELWCSVWLAVDVWMSTASILNLCVISLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPS2</accession>
    <name>A0A3R7PPS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3 4">Cuticular protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CPAP1</name>
        <name evidence="4" type="ORF">C7M84_002461</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2018-06" db="EMBL/GenBank/DDBJ databases">
            <title>A novel cuticle protein involved in WSSV infection to the Pacific white shrimp Litopenaeus vannamei.</title>
            <authorList>
                <person name="Yang F."/>
                <person name="Li S."/>
                <person name="Xiang J."/>
                <person name="Li F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <dbReference type="EMBL" id="MH550050">
        <property type="protein sequence ID" value="QEE04478.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001327">
        <property type="protein sequence ID" value="ROT78834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPS2"/>
    <dbReference type="OrthoDB" id="6342296at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033395194" evidence="1">
        <location>
            <begin position="18"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QEE04478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13353" checksum="CFA6D18118509FA1" modified="2019-04-10" version="1">MMKVLLILSALAVTAFGRMAGVLPGGFRINDGFSCDGRPYGFYADADNDCKAYHVCEPVVDEDGQLVEMAHYTFLCGEKTVFDQEQLSCATPGEAYPCANAAAIYEETNRRLLIEAEDQTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYK8</accession>
    <name>A0A3R7PYK8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_000129</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Receptor for basic fibroblast growth factor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001016">
        <property type="protein sequence ID" value="ROT81108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PYK8"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06366">
        <property type="entry name" value="PBP1_GABAb_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00192">
        <property type="entry name" value="PTKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000593">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001227">
        <property type="entry name" value="Tyrosine-protein kinase receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF489">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="17" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15 24" id="KW-0675">Receptor</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="13" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="828"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="884"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1190"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1287"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1215"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1247"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="917"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00056965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT81108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1312" mass="149857" checksum="CCB14F83A3BCAB5A" modified="2019-04-10" version="1">MLKEPPPKYVYDKSEQLQVPLTLDTSQRLSHQLTTAVVKILLEEGLGYQNVTIIKYEEDSFNSEIALSRLKSPPKQKSKPPKAMINLEVWLPPRFLEEDNIVKMDCAPARVSPGSPLAPRFGWYISNNSYTQTDQIMDHWRSFQRVDVVRIFELTQEEDATLQRDYTKSGDKYFCQHLNCTDGIFTPPICREGPCATLLVGDYNDFSAFLVDQVMDQHLRVRVAWIGPNLNHQFLCTFRNPKPLMFFDWWPNQLSNLEEFMPVSFPPCSSYKGMNSSYLCNYELHSLKKMIWSNLPETAKVAVELVKRFYLSEEDYRELLSLYTNMTSTCGRHASLITKSQSEIIEDVACQWLQRSHSNGTEVWVDWLPHDYAAKTVLWIGGIFPVNSKKNNGFTSATLLKAAYMATDRVNNNSEILQDYDIKLMVQNGGCKSEYVLASFIHYVRSETGSPPLEQMIGILGPACSDTVEPLAGVAKHFYTVVLSYSAEGAIFNDREKYPYFFRTIPENKMYGFVYSELFKLFGWKQVASLTEDCNKYSEYLTLLQNMLPKGVNLVNRKFPRAANRNMTDHLLKLKDKNLKIIIADFYAGTAREVLCEAYHLNMTAKNDYVWFLPRWFASNWYDTEYYAKDDAKKIPCNKSMMIEAVDRHMALGYAYYAHDDFKYHEGKTVGEWREEYKAVYLNHSQSLTADYAGYTYDAVWTYAFALDKLLKEDETHVSNLHSARTNKRFVEIISQTEFDGVSGHINFKDGPSRDATINIMQYVFDYNTMTGQYRTVGTFTSNDSQKKILNMKKQNTQFFNGIPGDGSLPNSCLFETFRQILDVRCEVAIVIVMVLIFAVFAMILIGLFIVYKKRFEKMLPEQPAWPLGELMSLDEWELPREKVVINRTIGEGAFGTVFGGECQFGENSPWLAVAVKTLKVGSTVEEKLDFLGEAEMMKRFTHVNVVQLLGLCTHQEPIYMVMEFMLYGDLKTYLLARRHLVSDKTVHSEEDEISSRRLTSMALDVCRALAYLTENRYVHRDVACRNCLVSAERIVKLSDFGMTRPMYESEYYRFNRRAMLPVRWMSPESIEDGLFTNMSDMWSYGVLLYEIITFGSFPFQGMSNNQVVEHVRAGNTITIPSGVKPQLERLLMSCWSKCPQDRPTFNEMAETLTMWPRLITPCLEVPSAAVQLNDTDSLEIVLPAADQPCRRSSAPTARLPNPRVRHTSGGDSIPASSNVQGNLLSRGQNVPLLSTTSTPAPPTTLNVSSWNRTPQENGGGPSVEPLLPQNGDGYMSRYVCLQRTKSGENNSDLDSPYNKNLYLDSPNMTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q020</accession>
    <name>A0A3R7Q020_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-like protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003151">
        <property type="protein sequence ID" value="ROT65039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q020"/>
    <dbReference type="STRING" id="6689.A0A3R7Q020"/>
    <dbReference type="OrthoDB" id="199041at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106370">
        <property type="term" value="F:protein-L-histidine N-pros-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007884">
        <property type="entry name" value="METL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890">
        <property type="entry name" value="DREV PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12890:SF0">
        <property type="entry name" value="PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05219">
        <property type="entry name" value="DREV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="165" mass="18880" checksum="DFCE048098257CFF" modified="2019-04-10" version="1">MNPHQPSHFRVLDVRSWMEETGDLEYDVITCLNLLDRCDTPKTLLKDIYRKLRPDGTLVVALVLPFSPYVEYGAADNLPSEELGITGSTIEEQVNSLANEVFPGLGFQLDRWSRLPYLCEGDLDQAFYWLPDVVLILKKMEISEENLYSPSMQELAKEVNLKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q121</accession>
    <name>A0A3R7Q121_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AP-3 complex subunit delta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023627</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000721">
        <property type="protein sequence ID" value="ROT83189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q121"/>
    <dbReference type="STRING" id="6689.A0A3R7Q121"/>
    <dbReference type="OrthoDB" id="10264595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904115">
        <property type="term" value="C:axon cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098830">
        <property type="term" value="C:presynaptic endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043195">
        <property type="term" value="C:terminal bouton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048490">
        <property type="term" value="P:anterograde synaptic vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098943">
        <property type="term" value="P:neurotransmitter receptor transport, postsynaptic endosome to lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016182">
        <property type="term" value="P:synaptic vesicle budding from endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048499">
        <property type="term" value="P:synaptic vesicle membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017105">
        <property type="entry name" value="AP3_complex_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010474">
        <property type="entry name" value="AP3D_dom_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058898">
        <property type="entry name" value="Mu_AP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781:SF12">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781">
        <property type="entry name" value="DELTA ADAPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06375">
        <property type="entry name" value="AP3D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26171">
        <property type="entry name" value="Mu_AP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01354">
        <property type="entry name" value="BLVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP-3 complex subunit delta" evidence="8">
        <location>
            <begin position="340"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="297"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="397"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="316"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="459"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT83189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="876" mass="98004" checksum="47A91BDEF284FF9C" modified="2019-04-10" version="1">MSKILKTHPKSVQAHKDLVLQCLDDKDESIRLRALDLLYGMVSKKTVMEIVRRLMTHMDRAEGTMYRDELLQKIILICSQNNYQYITNFEWYISVLVELCRMEGTQHGGLIANQLMDVAIRVVAVREFTVGQMALLLDNAHVIVGPAAARSSIAEVLYAAAWICGEFSQLLANPKATLESMVRGKVVSLPGHIQAIYVHNMLKLYAHIISTAEEEEDSEMIEEVTSLLLERLPVFVSSGDLEVQERASCILQLVNYVQKCHKNGDKIGSDLTLLLTGELNPVAPKAQKKVPLPEGLDLDVWINDPPSESEEEEKDDVFKKEIFVKNDPSSKERKKEKYEPTEEELQKRRDARRAEQASNPYYVKSHSSPRPNHNSLQVDEIPVAALDLNVSLKIPGMASLDKYQFVEGRQESGKKRDKKHKKRSKKRGVASSSSDEDVPRTHVVNTDVGEMPEGANFSDENEPDDRPEDDPHRALDINLDEPLAPNEVLPTRSHYEVPRKASSDNQDEANLLASPAKKKSSGKKEKKDKKEKGKKSKKEEKKVSRKKNGVPKKEESLILDLIDPLKETSISDETVPSTANHINGVEESSSKEPQSDDLDFWLSPENPPAEAHIEEADKVAQLPSSELHSKEESKSKKSKTKKEKKAKKDKEKHEKKSKKKAKEEPEAMSRNRDEYEETNGLSSKDISKLQLIVPDSDALKMIRTDPESDTVNLPWTLEAGRSRESQFSFTADDDTIPHKLRGSLSYTQEGIGSSDISFRLDFPVVTFLSGKTASRATFTDLLGSGQLSARSSFTLPSCSRSFQEVLDEVTRGGSLAVVESVDQTASLYGRSLHGHHVCLLVKYQASSRLTVDGKSTEGTLLSNTLDYLKTTLSQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q609</accession>
    <name>A0A3R7Q609_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative sodium-and chloride-dependent glycine transporter 1-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012315</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002562">
        <property type="protein sequence ID" value="ROT69479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q609"/>
    <dbReference type="STRING" id="6689.A0A3R7Q609"/>
    <dbReference type="OrthoDB" id="6354857at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="96"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="272"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="469" mass="49708" checksum="5F515EF0F8A1F2C2" modified="2019-04-10" version="1">MGKEDKKDVGSTEALDAEEDRGTWGNQCEFFLSCLGYAVGFGNVWRFPYLCYKNGGGECAGSGSGNGFGLGRRGGGGDENGGGECAGSGSGNGFGLGRRGWGGDENGGGSGSGNGFGLGRRGGEATRTAAGSGSGNGFGLGRRGGEATRTAAGSGSGNGFGLGRRGMGERRRERRRGVAQGNGFALAAFLIPYVIMLLCAGLPLFFMELALGQYVSLGPNILFPKLAPIFSGLGWGMIVVSALVAIYYNLILAWTLFYTFASFTSVLPWGHCDNDFNSIECFTEDAAANCRNQSLLYYNKSCISIDSYCSIGNLSSYNETYCEDLITGEIKKAEGSVPRISASEDYFKNRMLGVTGTTWDDMGGMRWELVGCLALAWIIVGACLAKGVKSSGKVVYFTALFPYAVLLILFIRGVTLEGAYKGVEFYLLRPNISRLGEIEVWNDAATQIFYSLGSSFGGLITLALQQVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q925</accession>
    <name>A0A3R7Q925_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial genome maintenance exonuclease 1</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MGME1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002272">
        <property type="protein sequence ID" value="ROT71630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q925"/>
    <dbReference type="STRING" id="6689.A0A3R7Q925"/>
    <dbReference type="OrthoDB" id="5777131at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008297">
        <property type="term" value="F:single-stranded DNA exodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043504">
        <property type="term" value="P:mitochondrial DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03030">
        <property type="entry name" value="MGME1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31340">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31340:SF3">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="22420" checksum="5F738BF21F8D7C78" modified="2019-04-10" version="1">MPLPNRIALEKWKAKMIKELGEEGFNKYRQELLDRGKLLHGCIQSELSGMTLSSDQTQAVSGFWTSVRHVIPNVSEVQVLESRIIHPYLYYQGAVDCVGSYKGMPILIEWKTSGKPKLSVKSMFDDPLQVVAYLGALNFDGNYRLRQPIESAMLVVAYDTGLPAHIHILSKGDCEHYWRMWCTRLSQFWTQLAANPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBD4</accession>
    <name>A0A3R7QBD4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002018">
        <property type="protein sequence ID" value="ROT73565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBD4"/>
    <dbReference type="STRING" id="6689.A0A3R7QBD4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="612" mass="67191" checksum="63094807601C8517" modified="2019-04-10" version="1">MFMKEGSDELVSRRPPPPPSRNKGVIAGYRFEAATRTNFFVRSWPTVTTPPPPNPPTPLPSLLSPLLPLLLLLFPPSLFLVSLSLFLVRSFSSSPLPLLLLLFPLSLFRVFIPFSLCVPSPLSSPASLTSLSPFFIPCVFIPFSLCVPSPPSSSPLPLLLLLFPPFLIPCVFIPFPCAFLLLFSSSLTSLSPFLIPCVYPFYLCVSFSLFSSPAFLTSLSPFLIPCFYPFSLCVPSPLLLFSSPTSLSPFLIPCVYPFSVCVPSPLLLSHFSFPFLIPCLYPFFLVRLLLSLLFALSSSSLRRLALLFVARLKLLAIAPETKDMRGKGHETRDSEITPSPLLPLRAASAHYQFVDFPDSSRVSESDIPPLPHATTSPPLLPSIHPATLNPHPSQHPHFHPFPTPAHGFSTPSLTPPPPPTPPPNPTVHPFPTPPTLLHPLHFNPSPTTHTPTHIHISTLPHPRPRSPPPPLSLPPPTPHPHPHFPPFPPPAHALHPIHYPHHHPHPHPHPHFHPFSPPRPRFSPPSVPSPTTPPPTFHPFPPPPTLSTPSLPLPPPPTPHCPSHPHHSLSLAPPPNADFTPPSPPLRHHPPHQYPTPSPPTRTNQSERKASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QF28</accession>
    <name>A0A3R7QF28_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative isocitrate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003089">
        <property type="protein sequence ID" value="ROT65407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QF28"/>
    <dbReference type="STRING" id="6689.A0A3R7QF28"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF60">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="3">
        <location>
            <begin position="41"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="23332" checksum="35CBBF9D57ECB80D" modified="2019-04-10" version="1">MLNLSPREWVSFSIWVPVVLPRRSFTASKPFPVAQYGGRFTVTMLPGDGIGPEMMSYVENIFRYAGVPVDFEEVEITKNSSEEEFANALTCIKRNGVALKGSIESKYGESGSSRNAALRNELDLFANVLHCKSYPAVRSVYQDVDIVIIRQNTEGEYSMLEHENVKGVIESLKIITRTASERLARYAFEYAVGHSRKKVTAVHKANIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHP6</accession>
    <name>A0A3R7QHP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">M-phase phosphoprotein 6 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001263">
        <property type="protein sequence ID" value="ROT79269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHP6"/>
    <dbReference type="STRING" id="6689.A0A3R7QHP6"/>
    <dbReference type="OrthoDB" id="20403at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019324">
        <property type="entry name" value="MPP6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13582">
        <property type="entry name" value="M-PHASE PHOSPHOPROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13582:SF0">
        <property type="entry name" value="M-PHASE PHOSPHOPROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10175">
        <property type="entry name" value="MPP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="166" mass="19011" checksum="CCD7440132AE6388" modified="2019-04-10" version="1">MSMEGEVKQNVKKLSKGVLELKFMKKTKEKAVLQEENEERQQLYQDQLSLLHKGADRIVMVDSYFDCMDFLPCRLSFGGMDPDIEKLNEDKLTGVYKTERILPAPNKGDGIEEDVTAEEIAENYSKLLGNKAKQFTKRKSDHNEFENTTEAEVPMMTGEERVGRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QID1</accession>
    <name>A0A3R7QID1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium/calmodulin-dependent protein kinase kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013447</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002671">
        <property type="protein sequence ID" value="ROT68399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QID1"/>
    <dbReference type="STRING" id="6689.A0A3R7QID1"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT68399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="342" mass="38722" checksum="151D242DD699E417" modified="2019-04-10" version="1">MSMKAGCRPRRVGGRPIENPLDRVHREIAILKKLIHPNVVKLVEVLDDPDEDNFYMAFELLEKGEVMEVPTDTPLTEDQAWGYFRDVVLGIEYCNTLPEEIHRDIKPSNLLLGDNGHIQIADFGVCNEFDGQDAFLTNTAGTPAFMAPEALSTSRHKYSGKAADIWAMGVTLYAFVYGKLPFHDENIVVLYDKIRNAPLVFPPAPFVSDDLKDLISLMLEKDPAKRITLPDIKQHPWVTAGNQYPLPTEEENCVLIEVTDEEVQTCVRSIPKLETLILIKCMLKKHSFHNPFKMNVLIKEQFARAGRSHSAPGSYEFYLDRKRSLDITLPAVDELEVCGEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLK4</accession>
    <name>A0A3R7QLK4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dual specificity protein phosphatase 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024087</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000779">
        <property type="protein sequence ID" value="ROT82755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLK4"/>
    <dbReference type="STRING" id="6689.A0A3R7QLK4"/>
    <dbReference type="OrthoDB" id="9979246at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45948:SF2">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45948">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="57"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="119"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22269" checksum="20EE65C9AE19A8F9" modified="2019-04-10" version="1" fragment="single">MVPKPWLIPAVSDVRFYPEGGLSPCSSQGWKDVAHHTTQLEDAPHAHTQWRTHTRTHPVEDAHTHTPSGGRTHATHAHIRTRPVVCNIGTHEGRTRTDQTRDKEYLCILASDSPGQNLTQYFPACNDFIHTARLKGGSVLIHCLAGMSRSVTVAVVYVMCVTSLSWRDSLKAVRGARNVANPNVGFLKQLQDFETDRMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPS0</accession>
    <name>A0A3R7QPS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001935">
        <property type="protein sequence ID" value="ROT74101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1215"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1449" mass="154968" checksum="812A4D2FB29F6A0B" modified="2019-04-10" version="1">MEKIVRAAGPRHSPGLQDLQYRRDVAPLTFISKTSQHLRRRQPRRQVTRTFRTEAQDLKPWSSPSQDSTSAEAACVKREEDWRSFRPASLNEPRQHLALGCSGSGNSGRRKALPGGSCPYLLLPQAGNPYLLLPQAGNPSLLLPQAGNPCLLLPQAGSSCLRQETQAGKPQAGNPSLLLPQAGNPCLLLPQAGNLCLLLPQAGNPCLLLPQAENSCLRQETLASSCLRQETLASSCLRQETLASGRKPLPPLASGRKPFPPLASGRKPFPPLASGRKPLPQARKGRNPCLLLPQAGNPSFLLPQAGNPSLLLPQAGNPCLLLPQAGNSCLLLPQARNPCFASSCLRQETLAPLAQERNPSLLLPQAETLASSCSGRKLASSCLRQETLASSCLRETLASSCLKETCLSKKLLPQALASGRNPCLLLPQARNCLGLRQEPLPLLPQAGNLLLPQARNPCLLLPQARNSCLRQETLASSCLRQETLASSCLRQETLASSCLLPQAETLASSCLRQETLASSCLRQKPCLLASGKKPLPPLASGKKPLPPLASGRKPLPPLASGRKPLPPLASGRKPLPPLASGKKPLPNPLPPLPQARKPLPLCLRQETLASGKKPLPQARNPCLLLPQARKASSCLRQETLASSCLRQKPLPPLASGKKPLPQAGNPCLLLPQARNPCLRQETLASSCLRQETLASGLASLASGRKPLPPLASGKPLPPLASGRNLASSCLRQGTLASSCLRQETLASSCLRQETLASSCLRQETSCLRQETLASSLPQARNPCLLLPSGKKPLPQARNPWPQENPCLLLPQARNPCLLLPQARNLASFASGKKTSCLRQETLASSCLRQKPLPPLASARNPSSCLRQETLASSCLRQETLASSCLRQETLASSCLSKKKKPLPPLASGRKLLPQARNPCLLLPQARNPCLRQETLASSCLRQETLASSCLRQETLASSCLRQETLASGKKPLPARNCLLLPLASARNPCLLLPQARNPCLPCLLLPQAGKPLPPLASGKKPLPPLASGKKPFLLLPQARNPCLLLPQARNPCLLLPQARNPCLLLPLASGRKPLPPLAQARNPCLRQASSCLRQETLASSCLRQETLASLASARNLASGRKPLPPLASGKKPLLKPLPLLPQARNPCLLLPQAQKPLPPLASGKKPLLLLPQARNLLPQAETLASLASGKTLASSCLRQGLRQNPCLLLPQAKPLASGRKPLPPLASGKKPLPPLASGKKRQETLASSCLRQETLASSCLRQETLASGKKPLPQARNPCSCLRQETLASSCLRQETLPSSCLRQKSCLPCLLLPQALRQETLAYPCLLLRQKPCLRQETLASSCLRQETLASSCLRQETLASGRKPLPPLASCLLLPQAGNPCLLLPQAGNPCLLLPQRFRLGAASDVTSGDLNSFLRQQCSPGASFNKAAIQPRWKSEIAVVPVVNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPS8</accession>
    <name>A0A3R7QPS8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Sodium/calcium exchanger membrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">C7M84_023987</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="20">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000077">
        <property type="protein sequence ID" value="ROT86002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPS8"/>
    <dbReference type="STRING" id="6689.A0A3R7QPS8"/>
    <dbReference type="OrthoDB" id="2127281at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008273">
        <property type="term" value="F:calcium, potassium:sodium antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000018">
        <property type="entry name" value="Sodium/potassium/calcium exchanger 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000009">
        <property type="entry name" value="sodium/potassium/calcium exchanger 5 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00367">
        <property type="entry name" value="calcium/sodium antiporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="SODIUM/POTASSIUM/CALCIUM EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846:SF74">
        <property type="entry name" value="SODIUM_POTASSIUM_CALCIUM EXCHANGER CG1090-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="10" id="KW-0769">Symport</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="420"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="19">
        <location>
            <begin position="48"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="19">
        <location>
            <begin position="314"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ROT86002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="49941" checksum="3231BD1B5E2CDC20" modified="2019-04-10" version="1">MPMSSSSSSRHLLQTDAWAGENCTQPAIEQFPRPLMSSAARRSGGLILHILISFYMFLGIAIDEYSCLREMICDSLQMSEDVAGATFMAAGSSAPELATSVIAVFVAKDDIGISGVIGSAVFNIMFVISVCALFAGQVIVINWWPLIRDSTFYCISICGLLLTIYNEKVNWYESVFLLLLYVLYIVMMFYNKRLEAWANTLNIPFKNATREEKSSLFGTKPVPPVGDDMKGEGAQDSENPAMDGQAVGDVPKEVEATEVESAGVKSMAPEMKDEDVSPWTMPVGVGERISWIVKLPLVAIHHFTTPDCRRERFTLGIPDTVMGLTFIAVGVSVPDALSSLCVAKQGFGDMAVSNAIGSNVFDILLCLGLPWFLKTAVVDPGSIVPVESRGLTYSTVSLFSTVVFLIVATHMNGWKLDKKYGVVLMFWYLIFMVFASLYELNVFGYFNPPECESSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QQ74</accession>
    <name>A0A3R7QQ74_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ankyrin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007044</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001896">
        <property type="protein sequence ID" value="ROT74448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QQ74"/>
    <dbReference type="STRING" id="6689.A0A3R7QQ74"/>
    <dbReference type="OrthoDB" id="448455at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050776">
        <property type="entry name" value="Ank_Repeat/CDKN_Inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24201:SF16">
        <property type="entry name" value="ANKYRIN-1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="30"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="457"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT74448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="499" mass="52547" checksum="B0E77F3326536214" modified="2019-04-10" version="1">MAQSGDAEGVRRLAEEGVDLKAASSMPDQRGLRALHIATIGGHARVVQELVRGGADINGRTTEGVCALHYAAAGGHTEIIGILTEAECDVNAETSDGDTALHLAVYHSNLSTVKCLIKGGVDFARGNKRGLTPLDIAAAARKADIASYLVEVSVKRALESEDTGILVELLRKGADLDPLIVKQSTEGMRAVHYAAWHGSLEMLRLLKEKNADLTATSVEGHTALHWAARGGQLDAVKWLLSHGGLDAACRSKDGATALDVALRLRKTDVADFLKSFTRGVGPANLDGKPPQTHEIEVNIKQRTEAGATDEAGVGGAVVRKGSGSTAGREGAAATAQGLAKTNAGTRAAGVAGAAPTNPQPRQGEVAQDPGLGQGTPDLDAKLLKAASDGDLQGVRFCLSAGASVEAASSAMGEERVVFPERKEKWLRPLHLQRGRGTWASFVSFLVEAPNSKARGREGYSAIHYAAKGGHIDVLRILHEKMWQHESQNRQWADDPSRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QT02</accession>
    <name>A0A3R7QT02_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001575">
        <property type="protein sequence ID" value="ROT77037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QT02"/>
    <dbReference type="STRING" id="6689.A0A3R7QT02"/>
    <dbReference type="OrthoDB" id="2020426at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12600" checksum="548719CFEF133F52" modified="2019-04-10" version="1">MTPVTSAVTTAGDTFITTTDIHTRQESADSGLGLGTNYSLPHTPEDFLASMEDVEITPDVEMKTSPANNILEAPELESMDSEDLVQSIQLNDDLSTDFLNDMLEPSKIDNLHTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QXN6</accession>
    <name>A0A3R7QXN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000863">
        <property type="protein sequence ID" value="ROT82192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QXN6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="48404" checksum="B710D6D9DDC0042C" modified="2019-04-10" version="1">MTPYNRLFDNTGGVTAIAVHGSSAKAARESFGDVSCSQALRDESVEGEGGKGIYIGAKRKATAPIVSAMKSLLCCLLCIAVGVQGWVMPYGPRPMGPAPLFEPWWSMGVHPPSWMLGPRSPWWQEGLWEMSFNVGCTPLIIAQLACKHGTYVDSENKCKCSAGLNQICVKSDQDTRRCAANLECSSKTGRCVPVADALSTPFVGKEADRTDDLAFCARYGRRKSWHLAVSHICCPSSSSLSQHCPLTVPSPSPHYPLTVPSLSPHCPFNMFSLPPHCSFTVPSLTPHCPITALSPFLSPSPHCPLTIPSLSLHHPLTVPSLSPHHPLTVPSPSPHCPLLPSRYHMRAVCLPVHLPGLPRVQRSQRLGAGGLLRPVRGHLPVRCGLASTQISHLALIPNITQDPNDRTELNAIRWAKDLALEILHSILVSSPTTGRPESSRSSVPVIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SK24</accession>
    <name>A0A3R7SK24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017728</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003266">
        <property type="protein sequence ID" value="ROT64331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SK24"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="41916" checksum="8577A27936D56B1E" modified="2019-04-10" version="1">MTTFMNSTSLNTVDDDGSVVRDTVDSTVDTPGRRRHRGKMNVEDDTVDDDSVDDDTVDDDSPPTHPSQSYRISPSPLPPYVHPPPTSLPASIGLLPLPFPFASFSPPASLKAPLPPSPPPLRIGPLLPPASLKAPFPPPPPPLRIGPLLPPLPLSNPLPPPPPPPASLKAPFPLPPPPLRIGPLLPPCLSQSPLPPPPSTPSHRPPSPPPCLSQSPPSPLPPPPLRIGPFSPPASLKAPPLPSTLRIGLLLPPLPLSSPFPLPPPPLRIGPSPPCLSQSPFPLPSTPSHRPPSPPLPLSKPPSPLPPPPLRIGPFSPPPRLSQSPLPPPPSTLRIGLLLPPCLSQSPLPPSPSTPSHRPPSPPLPLSKPPSPSPPPLRIGPFSPPLPSLKAPSPLPPPPPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLK3</accession>
    <name>A0A3R7SLK3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003007">
        <property type="protein sequence ID" value="ROT65980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLK3"/>
    <dbReference type="STRING" id="6689.A0A3R7SLK3"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053299">
        <property type="entry name" value="ASTRA_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44156">
        <property type="entry name" value="SUPERNUMERARY LIMBS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="106"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="45149" checksum="C8C8A765226D3F34" modified="2019-04-10" version="1">MKRTGGEFSNEPQEKKSRNGEEEMESCDVSTTSPVDTAKEGKQEKPAGTSQKTSRLPQALAGEATSKQDVSQEKIPQPTKGKSVEPTKPKKEPCIWRDTNYKVYTLKGHNDIILDVDCSDGYVLSASRDTTVRVWRVGGIEEERSLRGHRASVTSVAFLPGELAATVLAKLESEYEEIPSVQGQHSPECRVLAVSGGLDCTVKVWDIISGESHGSIYTYNGITCLSCGTWGIVTGTEGGKLEIWCVSSGQRFAFVNAFESQVISVSVKGNLIYAGSFDGEIGIWKYDSKERTLGTQYLLEPESPTPVSLKQLSCLAAHGDCVYLGDSGPNIKKFNWKKMQQLNREPSFIVRSLKHSHLICAAVLALVVAVAVGDVDLRQLVDHDLCVLDDTNIAQRHQGSDWELKGNGQLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRI2</accession>
    <name>A0A3R7SRI2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132367"/>
            <dbReference type="ChEBI" id="CHEBI:132368"/>
            <dbReference type="EC" id="2.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.17" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SRI2"/>
    <dbReference type="STRING" id="6689.A0A3R7SRI2"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000021">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018379020" description="UDP-glucuronosyltransferase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="496"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT71876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="533" mass="59906" checksum="86310C5B062079A3" modified="2019-04-10" version="1">MGVQSFGCRVLYLFCLLSAAHAHREPQERTEGANVLILHPIYAGSHELTLRKFGEKLVERGHRVTQLRWRSSKTRPVSSSVEVITLSPDNHDLRYPYMNQDGTFQPPTSMLWERPRHMWQLPTDVFGLMDAHCEAILGDEGLKSRLRSANFSLALVDIIANECSLALAFDLNLPVVGFWGFSFQGAESRAAGVFQSPALVPNFLSEVGATMTFTERVWNTLVMLAETAIITYHFTVTDGHIKRLLPSSPTSRELLREMEVVLVHSHWFIDYPKLMPPHVQYIGCIQCGPPSPLPPDLEEWVSGAGEAGAIVFSLGYTGYEANTVPPHIMEAFVNAFARLPQRVLLRFNAARLSVIPDNVKVLEWFPQHDLLAHPNTRLFVTHCGQNGLNEAVYHGVPIVALPVFADQGDNARRVVDHGLGLAIDKDSISESVVFETITTVLNDTRYTETVKRFSSLWQEEGESGAERGARWLERVHRYGRLTHLRMPGAHLSFSQYFALDVAVFLILVAAAPWCLAYWLCCRRKHGKSKIKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSP0</accession>
    <name>A0A3R7SSP0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GST-N-Metaxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002040">
        <property type="protein sequence ID" value="ROT73296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSP0"/>
    <dbReference type="OrthoDB" id="5809458at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03193">
        <property type="entry name" value="GST_C_Metaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026928">
        <property type="entry name" value="FAX/IsoI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033468">
        <property type="entry name" value="Metaxin_GST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050931">
        <property type="entry name" value="Mito_Protein_Transport_Metaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289:SF41">
        <property type="entry name" value="FAILED AXON CONNECTIONS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12289">
        <property type="entry name" value="METAXIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17171">
        <property type="entry name" value="GST_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17172">
        <property type="entry name" value="GST_N_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01180">
        <property type="entry name" value="SUF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01200">
        <property type="entry name" value="SUF1.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="3">
        <location>
            <begin position="91"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Metaxin glutathione S-transferase" evidence="2">
        <location>
            <begin position="232"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="311" mass="35737" checksum="F4729FE66722F484" modified="2019-04-10" version="1">MALVDASPNFSRMALVSAGGWAPAHFVGRALRWLWCKNRPVTFALAAVVGVVKIRQHQKRRERRRKWNEAGKDVVVLHMSRRGYSCPSLSPFVLKLETYLRMAEIPYQTDFEEPLGAKGKSPWVTLNGEDLADSQLVIEWLGPKFGKNLSSHLAPQEKAVAHAFRVMLEEYFLWCLAMWRYVKERGRPVVENMYLPMPLRLMMPLLVKNAVKATHAQGIGRHSHQDVEEMGRKCLHSLSTWLGDKPFLTGDKPAEVDCSAFGTLAQVVWCSPNSPYLRMLESDFRNLYDYCHRMKEKLYPDWDQCLDNSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSX9</accession>
    <name>A0A3R7SSX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative janus kinase and microtubule-interacting protein 3 isoform X7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002017">
        <property type="protein sequence ID" value="ROT73582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSX9"/>
    <dbReference type="STRING" id="6689.A0A3R7SSX9"/>
    <dbReference type="OrthoDB" id="6374446at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="807"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="960"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1074"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="590"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="515"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="825"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="862"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="878"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1125" mass="127184" checksum="0388C0B0D25922E1" modified="2019-04-10" version="1">MSDNDPLTTMTTLPHNPSDDGEQYRASTEARLATTTAPQGMKEKSFCEVAEEGKPHLKETQEEKENRSTHFPFLRMPKLKREKSYTETLERKKKRVKFSPNDDDDDGLVVDTRVFEAHAVSAHDGDADDGVLSHKIKKLLKKRSKRKKSSIETQTDGNDDGQNQDATKATFLKDKQEISSSRDCDRTREPLPSSPKGHYKFEVDVKHHVDVSDVSSPDCDATEPSAAAAAGGSPSAEPLSAAADSANHDVSVEAGVPTVPIPSTQEIENDLSPRVENENNTSLLEKEHDSASKENDETSPASAESAAKTSECEIYLVEGPVLEGQELEICLDRGEDEFHARQLSKENINLISSTEEESNPTSCQATVKREGTFTLDGPPPAKITKSSCDAVGDASRKESSLLDDSREPVIFFVDLDSCEVKKPEEPQAMKARAERSPRSRSKSRSPQNQAKTVRAKDAAAKPQEQSSTVTSLKNTAKRTFVSAWRTAMKAQDSSEKGSKLTRSRDAASSKAAPASDERNTKVLRKKSDPKVPKNVTWDKKVTLKEPQESSRPNRDPLRSLYLQPLRPLPERSSMWSGVCLPSMRREGTFTKKYDSEKDRLQAECNRLNVEKERLQSELSEARIRLEEEITARKALRRTHELNLRQLREGELRRTEVLLADLRNRLEDEKREALDQQKGALTRIHESDLIRVERERDEDHRRLQQENKAAQEKLRADMRREVTRAEPPQVQCCHSTDRDLDRLNRDLSTLREHKKRLEDAVMTLQESERKRAGELRRLHEEHEAAVARIHRANKSEVARLLDEVRSKDRSIGQLERQLSAQSAKIRLQEEKAREASNDRTEDAARKRTTRGGGSGVSSKRHKEAATTKDGRTREKESCASATGPVNNNSVKSNHNASRGSPDVGADDTCQRTRAAQEEGATPEMAAQVEELSQEVEQQRELIEQQRQQIELQLQQLEETAKELEQQKQKWDEEKQAMKQEMEEQKATVEAEREELQHQIEDKIHQVEEQKLVMEAQKQVMEDQKQVMEEQKQVIEEQQLRIADLAEESMERECLPPVPPPPTWHPRRESCVKASPFETAVPHPESSRQRARGEEREVAALSLPRQVVLRTPYHVVGAHAVPYRLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUR4</accession>
    <name>A0A3R7SUR4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynein heavy chain AAA module D4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005418</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001701">
        <property type="protein sequence ID" value="ROT76029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SUR4"/>
    <dbReference type="STRING" id="6689.A0A3R7SUR4"/>
    <dbReference type="OrthoDB" id="5593012at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF70">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 2, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="3">
        <location>
            <begin position="2"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT76029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="307" mass="35215" checksum="14201C68DB4B27C0" modified="2019-04-10" version="1">MKAGGEGRPTVFLLTDTQIKDEAFIEDVNTLLNTGDLPNLYSNEEKAEILEKIQLVAKEEGKKMDASPLTLYGYFIDRVRSNLHLVLAVSPVGDTFRTRLRTFPSLINCCTTDWFTPWPEDALERVAHSLLQDAQLEPSLLQRCVEACKFFHHTMDVLGARYFEQLRRWCYVTPTSYLELVLTFRQLLLKKRSEILMLRDRYVTGLEKLKEAKLLITELQEELKMLQPRLVETSANTEALMIKIEQDTIQVERKKELVAADEAVANRKFADARPSRTTARRSWPRPCPPSTPPRTPSTPSSRTTSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWA2</accession>
    <name>A0A3R7SWA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001403">
        <property type="protein sequence ID" value="ROT78283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWA2"/>
    <dbReference type="OrthoDB" id="6376853at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="126" mass="14609" checksum="F358BCEAE84A7BBA" modified="2019-04-10" version="1">MGLRKIVQNGKTSYMYSSSSQEELFLVLLQAGSAHSMKITAESDTVQRWCRNLEKTPQEYLSLACQAVENLSSVRDSDGKDLKEDIFEIQDDHLVWKQYFPEKKVYGRRGKFTLEKMEYDDALENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T183</accession>
    <name>A0A3R7T183_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative nose resistant to fluoxetine protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020416</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000400">
        <property type="protein sequence ID" value="ROT85198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T183"/>
    <dbReference type="OrthoDB" id="118951at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052728">
        <property type="entry name" value="O2_lipid_transport_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161">
        <property type="entry name" value="O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11161:SF0">
        <property type="entry name" value="O-ACYLTRANSFERASE LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="421" mass="47193" checksum="83DC46EDC7EC087A" modified="2019-04-10" version="1">MKDQATAFSLFPYTNAPFQANTPNCCCHALPGDGRSFHTVRPLAPSVNTLYKSCSDNWWMDVLYVNNFLAFNATTNTLTDCLGQCWYTAVDTQLYLVAPFVLLPLAFYPSKGKILLFLVTLVSFIIPAAVTYAYDLPPGRSGAVMSNNVDNTGYERKVYYTPWCRMSAYIVGIWTGYIIFNQGSKKLVLSPVQVLTGWTVAVFSALAVLLGAWSYNHIGTTYYYDPITQVLYGGLHRGVCVSLWLGWCGLSLRLRRCSEYFPLSSFVAASLSPHILHVPRRASHSDHSDFQHQGPSLFHPCEKIIQTCGTVFLSLIRPVALAHGSSSRENYIQATQESTFSLASVFCQRSPPSYNSPRFLRHRSRMTTQELQLPHEKQGQDNLASPEKWTRKADLAKKEEAAETVTSRSSQTPYSEKEQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SC89</accession>
    <name>A0A423SC89_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003998">
        <property type="protein sequence ID" value="ROT61773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SC89"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="43333" checksum="458DE8E729BAD472" modified="2019-05-08" version="1">MNSCVGRAEGFMSSSKRDREIARRGEFRTSVITALANWYSNYWYRVHPAVLMRSLQGCEYAFVTPTFLYLSSSLPLLRPTSPSLSFLSFVFSNHSPSIIFLFLPCFPLLSLSSLSPPSILPASIPLFPSSSFHSSRFLSFFRFYPPFLPPPSILPASSFSLPFFPLLSLFPSSSSSRFYPSLPFPSFILPAYPSFPSSSFHFFYPASTSSPRHPLASLSFPSILRFPYHFSSLPSSFLLSSRRFYPSLPSPRLYPSLPFLFFHLPSSIPLSLSISPSPFSSLPPSLFSPLPSLLLPFSLFIPLFLPPPSILPAFIPLFLPLPSIFPASIPLFPSSSSILPAFIPLFLPPPSSFSRFYPSLPPPSLFRSSRFYPSLPPSSSPSLKKGRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SD59</accession>
    <name>A0A423SD59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003825">
        <property type="protein sequence ID" value="ROT62114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SD59"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="562" mass="59873" checksum="6C637F3EED29CA7C" modified="2019-05-08" version="1" fragment="single">LSFPASPCLLSSSPHSPFSHSFSSLLLLPSFALLWSFSVSLPSSCASASSSPSCFPLPFPSLTTFFLSFLSFNLPFLPLPFSPSLPPTAFNFQFSAFILNPFPHFPISSASPLTFHPYSLTLSFLLLLLSLLVSSSSFFLLLLSLIFLISSSPCLLLPSSHTFSPYPFNFLIPLPLPLSPSPYPFSLPYFPIPLPASPFPFPFPPYTLPRFYLLPSPNLRISCSSRSSPQIPLACPSCPFPSPSLSSPMPFSRSALLPPSSFPSLIPSPLSRSPLSPSSSLSSGFPSLPLPPALPPHPVPQSLPLPHPFPPAPSSLCSPFPLPSPMPDSHSPPRIPCSLPSPSLPPSAFPSSSPPFSFSLPSSPSLSPPSPLLPPAFPCPHRLSLSSFLPSLPLPSIPSALPALYARAPSPLPSHSFLPSLSLSLPPLPLSFVQLLSLRFCVSFPSIRLYPLSLPSPLPLAHLLHVPSPSLWPLLFSLPPSPLPPLFPLPFLPSFSHPSSLPSFPSPITRLSPLSPTSLFLIGVLTAVRRVFVPLSGCDSIEASSAQVPIPGTPRIAIQVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIQ7</accession>
    <name>A0A423SIQ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017921</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003312">
        <property type="protein sequence ID" value="ROT64148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIQ7"/>
    <dbReference type="STRING" id="6689.A0A423SIQ7"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000298">
        <property type="entry name" value="Methyltransferase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="109"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="422" mass="48157" checksum="A21A0D28D8B12C65" modified="2019-05-08" version="1">MSEEGARNVPGKRPQFGARFLKDKKNVFEHNAWDNVVWDDTQEAAALAKVQENSEVTLTPEDIQKLEEEAAHHWDAFYGIHQNRFFKDRHWLFTEFPELAPHLAHTFPRKIQPGEDMDSNDIPASDSDGKVPAEPQSNEVDKSQCDDCPESSTNTKRQNTPDCTNSPKDTHKVEDTEQSELNEGDEANSKSSASAEGREDPKKSNVLRQDESFPGEKSSYRILEVGCGVGNTVFPILKVNNDPELFVYCCDFSSTAVDIVKDSPDYDTDRCRAFVCDITSEDWGAPFPKNSLDVIVCIFVLSALNPEKFEHTVRMMADYLRPGGLILFRDYGRYDLAQLRFKKGRCLSENFYTRGDGTRCYFFTQDDVRKLMTDAGLEEVQNLVDRRLQVNRGKQLTMYRVWVQTKYRKPAVQDTQQISVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SK32</accession>
    <name>A0A423SK32_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003242">
        <property type="protein sequence ID" value="ROT64523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SK32"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="379"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="519" mass="55240" checksum="AA5ADAED0CCA851B" modified="2019-05-08" version="1">MVAEPPKHEGDPHSSKDDLHNQLPHKGNVAGEEAAPAGQHVFPGHHGPLALSSSASGRNTPQQDCDEEEPGPAAHQAAARARVHAGGQPSEQVPVGKGSSDARPRQMTEVPSDDMGAWRRPQREEAEVQRDAEAGAAEGGVHTGRATPRGSDSCSKLPDGDAVRREQESRGGAVRRKSFDGGDGKYARGAGLMARPSARSVSNVSKGAVGRVSEAELRPRGGTLPDLSDFERVWEAGPEVIVKLARLASAETLTPTEGYTPTPTRTLDSLAESRSVSTDPSAFQETQETPHRHADEDEDWPRRDDGLVGAVGGGGRACGCGVQVGGLDETCGRCPSCPALTDVYVSEQFPSSDPLECVDGSTHTLHVDVTTGEVKWRVAEPDGKMPPPEPPLDPSKCLDMPPQRPPAPTTSGEAESQTRREFTWVGHAGPCVMGALFAGREWIWWIRWMEGFGAALGRKAAPGTRRRRRIFGSRDFEGDPGLEGGNGGRDVPGASGAATPFPGTLQRARPRPGRRRQHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLY5</accession>
    <name>A0A423SLY5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cuticle protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003116">
        <property type="protein sequence ID" value="ROT65236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLY5"/>
    <dbReference type="OrthoDB" id="6423516at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF79">
        <property type="entry name" value="CUTICULAR PROTEIN 50CB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14524" checksum="868E672C07BD1814" modified="2019-05-08" version="1" fragment="single">FAVLAFVVGVALAAPQYDYEPPSAPSSLYETPAESVQEPVQLYEAPSENVLVAEPQNLVPDVVSPPQTMEGMPYEFQWGVEDGESSNAFSHVESSDGQTTQGEYRVLLPDGRTQVVKFFDDGNGFNAEVTYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMC8</accession>
    <name>A0A423SMC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003107">
        <property type="protein sequence ID" value="ROT65284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMC8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="46158" checksum="DD649FC92DB9B0EE" modified="2019-05-08" version="1" fragment="single">MFISFILFIFIFLFTLLNPLLLSPLPTLSPFPSYLYFLSPFPLLSLPLPLASSPSFPFLLPSPVSLLSCLPPLPFLSPTTPSPSLKPFSIALPFPPLALVLLLCYSPFPSNTLSPLLAFPFFRLPSFYPPSFLPLIILLLLSPSLPFLFPPPLLSLHLPLLSPPPASTSPSSPSICPFSLFLPPPLAPPPTSTRPSSLSPSPYFPLHPLLPPASPSSPLPPFLSLHSPLLSSLPSSPASSPPSTSPSLLSSPPLSFLSPSSASTTPSLPSTLPPLPPPSPSPLPLLLPPLLSHPPAPSSPPLAPSLLPPASPASSPLLPPPPAPPPPSTSPPLPPLRSSSPSTSPFSPLLSLHSSFPLLLPPPPAPSPSLAPSSPSSRLHQPSSPSTSPSSPSTSPSLSSPSTLSSPLLPPPPAPPPLPPLALLSSPPASTSPSSPSTSPFSSLSPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNH1</accession>
    <name>A0A423SNH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_016246</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003038">
        <property type="protein sequence ID" value="ROT65775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNH1"/>
    <dbReference type="STRING" id="6689.A0A423SNH1"/>
    <dbReference type="OrthoDB" id="2544694at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT65775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="44970" checksum="9B6F307337A8C80E" modified="2019-05-08" version="1">MSSKFDGLLIQLGTGKWNMLYFLASSYWCLLVPPQFINGVYVAPPLRYTCRPPPDANVTSVSDNSCKYSTNGSSGVEEELPCTEWDFDTSVFTSTLTSEFDLVCDREHLQATYQGIYMLGTFVSPLLGGYLADRYGRLVVVIITQVVVSITSVGIVFLSDFTFILAVRFVMGSVNLLTFFVLAMEVCEPKHRSTVGILIGLPWALGTMWWGMMAFFIRDWRWLQLAVSLPTVLIFPFLYVMDESPRWLIVRGHHEKALKVLEKAARWNKATLPAPSSLYALMSEIQEESTTAKHKPKAGEKNKKCGFPSMPALLSTRAITTITAVVCLDFFAVSLVFDGLNLSGANFSADPFLYIILGGLMEVPGYSLTAPLIQRFGRSRLAFALTVCIFADIIRTIAIFLLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SP14</accession>
    <name>A0A423SP14_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_016043</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the GAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003009">
        <property type="protein sequence ID" value="ROT65975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SP14"/>
    <dbReference type="STRING" id="6689.A0A423SP14"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="9">
        <location>
            <begin position="184"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT65975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="269" mass="29011" checksum="28D9FD5D48B4B63A" modified="2019-05-08" version="1">MKLQNALGVCSSFRGGRGGGFGGRDQGPPERVLEYALFTHTAQEDLVCKVTHKDVPYFNAPIFLQNKEQIGKVDEIFGTPHDKYISVKLGENFKASSFEKDTKLFIDEAKLLPLFMFLPGHKRGGGRGGRGGREVVCRLLAASGNISTADRVRLDTVRMALCRLIYQSGVQGVRSYSTGGLNDVVIVSAVRTPMGSFSTIIAWGTALGTVAIKAAVERAGVDPKAVQEVYMGNVCQAGAKQAPLDKLHSLQVSTRALPVQLSTRCVPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRG2</accession>
    <name>A0A423SRG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">COP9 signalosome complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015189</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002890">
        <property type="protein sequence ID" value="ROT66763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRG2"/>
    <dbReference type="STRING" id="6689.A0A423SRG2"/>
    <dbReference type="OrthoDB" id="422427at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048624">
        <property type="entry name" value="CSN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF2">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21151">
        <property type="entry name" value="CSN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="271"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="532" mass="59446" checksum="90B82EC80DCBC591" modified="2019-05-08" version="1">MPLQLQGGQMQNNVEPMVIDMAVEENDNTEEEPVIVESTSLDLETYANSYTGLAKLQRLIFIADRCPQLRVEALRMAIHYVQTTYNVNLYTQLHRKLQEAVSGANAGNASLPDIAGGQVGGGSVANLPALDMQWVESRAKKAALKLEKLDTDLKNSKVNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSFRHIINMCLNVIKVSIYLNNWSHVLSYVSKAQATPEASESRPSSNKDQSAVIQTKLTCAAGLAQLATRKYKAAAKSFLGAQLDACDFPDLLSTSNVAMYGGLCALATFSRQELQKLVISSSSFKLFLEVEPQLRDIIFKFYESKYASCLKLLDELKDVLMLDMYLAPHLNTLYTRIRNRALIQYFSPYMSADLEKMAAAFNTTISALEDELMALILEGQIQARIDSHNKILYAKAVEERSMTFERSLEMGREHVMRVKGLILRSALIKNQIHKFLSSNLLKNSPSNWSSEGSICDRAEPISPPGITLAYLIDFRIHTGITAAALIEVKMSRWHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STZ2</accession>
    <name>A0A423STZ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RWD domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002785">
        <property type="protein sequence ID" value="ROT67633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STZ2"/>
    <dbReference type="STRING" id="6689.A0A423STZ2"/>
    <dbReference type="OrthoDB" id="10045773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23817">
        <property type="entry name" value="RWD-RWDD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042770">
        <property type="entry name" value="RWDD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21275">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21275:SF1">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="190" mass="21890" checksum="AC81B132D4E5B5C3" modified="2019-05-08" version="1">MREEHEEEREVLQSIYEGDSNFSMINETTFQYKYGDEGENRSFLVEISWGADYPDVAPSINLDLFYNKHIVSTVKEKIMSGLKEQAEINLGMSMTFTLFEWLKEAKEELLEEQPSEAPVNRIAEINSDVGQMTLNDDQGEGKKDKKEQLTKAQKRRMWDRQNAAGERARGYNWVDIIKHLSQTGGSKNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVS1</accession>
    <name>A0A423SVS1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002692">
        <property type="protein sequence ID" value="ROT68320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVS1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="425" mass="45488" checksum="CF295BB7F27603EF" modified="2019-05-08" version="1">MNEVTAVKRKISRCRPCISHSPFLISSLFFSLPPLYHLFPPLLFIYYSSAFPFSSFFSLVFSHFSLFLFSSPISPHILSPLFLPPLSTSIFPSFLSPISPPLFSSPISHFLFISPVPCLLSLSPASSVSLQSPFTFSFLISITPFFSVSHLPPLSPSSLLPFFLSHLGSTLLTLSNSTPDFPPTPTLLSLLPSSHTSSSPPVCPTSPHSLPRPSLLPPALLPPPFPFLPPPFPSHTPPLPPTLPSAPSPPSPSFSPSFPPPFPLPHLPPLPPTLPSPQPPPPPSFPLHTSLSPPDPPSAPSPLPPLLSPLHPLPPHTSLLSPRPSFCPQPSLPTPPFPSLHPLPLPHFPPTLSSAPASLLSLLHPLPLPHLPPPPDLLSAPALPPPSFPLPSSSPSPPPPFCPQPSPSFPLPSLPQRLQEIQRPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWH8</accession>
    <name>A0A423SWH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">AmphiDkk3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_013374</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dickkopf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002662">
        <property type="protein sequence ID" value="ROT68483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWH8"/>
    <dbReference type="OrthoDB" id="4321958at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039706">
        <property type="term" value="F:co-receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048019">
        <property type="term" value="F:receptor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006796">
        <property type="entry name" value="Dickkopf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039863">
        <property type="entry name" value="DKK1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12113:SF31">
        <property type="entry name" value="DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12113">
        <property type="entry name" value="DICKKOPF3-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04706">
        <property type="entry name" value="Dickkopf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019523345" evidence="8">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Dickkopf N-terminal cysteine-rich" evidence="9">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT68483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="211" mass="23957" checksum="CD5D8ADD4BCD6B03" modified="2019-05-08" version="1">MNLCLFFLTVGCLVTPCMAQGLSWLFRRLHKAGRHNIRDLSGGRHNSRQVAADQPFNFYEHLRLCTNDRVCGRGQFCDQHYGVCRDHVTEGHECRRDAMCEGGYACMFGLCQKRIKRGREGARCRKERDCGAGMCCARRHGEQVCQRRVPLGHKCYVPEGGLDYSMNQLCPCESGLVCKYTAQQPPSRHQLMALMSAHEDMRCAAPSHRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWT2</accession>
    <name>A0A423SWT2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002649">
        <property type="protein sequence ID" value="ROT68645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWT2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="700" mass="74744" checksum="8F5779E529420C06" modified="2019-05-08" version="1">MTHPTLVERRLSPPFHSTLSLNYPCAKHIVDTDHKLYPLCRFLPFFLFFGSFSILLSVSVSLSLSLILLSPFSSLSLLSPSPSLPLPIPSLPLSSPLFLSPSPSASPLPSLQSPSLPPSLPLSPSPSLSLLSLLLEFQSTLLAYFIKSSQTQTYPPPTPVTSSPPPPHHPVLLPLLLPPYLAPSPPPLLFHLTPFLSHLLSFLLSPSSIPPPYLVSSLLPFLSPLLSYTSLLPILIPTLHPLLLLLSPTLSPSPFSPPSPNPFSFPLFSSLLPSPPSSPPSLPPSPHPSFSSSSLPPPLPSPSPLPFPSPSTSLLPLPPSPSPSSLAHPLSFPLPPPSPLRPFPPPPPPLPTLPLPLLLPTLLLPPPSTLFPPLSFLPPPPFPPPPSSLPSPLLPPSLSFPPSGPPPPSPSSSPPHPLSFPSSFLLLLPPSFPLALLPSSSPLPPSLLPPPPSPPPSFLLLPPPPPSPPHALLLPPPPSRLPTLSPSLLNRLNIRPPLVPAPGSQAQEVQFIFSQNRPCEGYLPPPTPPITIPHCPSSSYTLLPYPLTLLTHFLRPFLPIPLLPPYLPYPLPPPFLPLHPIPTSSPPSHHHLLPPYLPYPLPPSLPSLFTPYPTPQPPHPTPHYPTTPTHHSSTPINIDLQFLSLILITGASYRGPSLPADELDAAEEPGDRGAPFSPSILILNVSVIRKLARLSQRFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYD9</accession>
    <name>A0A423SYD9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Actin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012619</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SYD9"/>
    <dbReference type="STRING" id="6689.A0A423SYD9"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT69245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41630" checksum="9D3C5A1801579873" modified="2019-05-08" version="1">MCDDEDATALVVDNGSGMVKAGFAGDDAPRAPSSPPSSAARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKVWYHTFYNELRVAPEECPTLLTEAPLNPKANREKMTQIMFESFSVPATYITIQAVLSLYASGRTTGEVCDSGDGVTHFVPVYEGFALPHAILRLDLAGRDLTHYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFESEMNVAAASSSLDKSYELPDGQVITIGNERFRAPEALFQPSFLGMESAGIQETVHSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILSSLSTFQSMWITKDEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T079</accession>
    <name>A0A423T079_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002534">
        <property type="protein sequence ID" value="ROT69678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T079"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="491" mass="53316" checksum="3023ABB1A3228A5E" modified="2019-05-08" version="1">MKMAVIGFKGTGQKKPLHRNQLEEQQKSSVNHTTTLSPLSSPLLPPPFPLPLPPPLLTPSPPSPPSLPYFYPLLPSLFSSIPYFYLLSPFPPPFLPPPFLFFSLPPHFYLLPLPPPLLLLPPLPSPLLPPSSLPLHPLPLLSSLPHFYLLPHFPSTLPNFYLLPPFLSTLLSPSLTSTSFLPSPSLPLLAPLLSPFPSTLSLSFPSTLPPSLPSTLPPLPTSTSSLLPLPIPPALPHFYLLPPLPSPTSTSSLPLPTSTSPSLPPTLPLYLLLPFLPPSPSLPPSTSFHPFPFPLHLPPSLPPSPPPPPSLSSLHLLHPFPFPSTSSIPSPSPPPSIPSPSPPPPPFPPLPLHLPSLPLPPPPPSLPLPLHLPPPLLPPPSLLPLPSTLPPPSLPHFYLLHQSNFNALFSHLCSLLSLSIYLSFHPPSLHPPTLPLFQPFILHPPTLPSFHPPIRSSHPPILPSSHNSAPFLWMRPVRSRNRMCYLERPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3R7</accession>
    <name>A0A423T3R7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHK kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002345">
        <property type="protein sequence ID" value="ROT71081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3R7"/>
    <dbReference type="OrthoDB" id="6343766at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015897">
        <property type="entry name" value="CHK_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004119">
        <property type="entry name" value="EcKL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11012:SF30">
        <property type="entry name" value="PROTEIN KINASE-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02958">
        <property type="entry name" value="EcKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00587">
        <property type="entry name" value="CHK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHK kinase-like" evidence="1">
        <location>
            <begin position="189"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="469" mass="53926" checksum="D50E9DD9BAF5E40A" modified="2019-05-08" version="1">MPGHDSFPWRRKRRRSLHLSVWQLGSTVPVPCKPANASADTAGQRWVAYVFTCETMEGDGAESDFRPSEITQESVEAALKNDKGSDARLVSFAVQECTKKGDNYATSVARVIVNYTLWETDHETSYVVKYNPRNFAAFEKFLYVVFRKEVMFYQHLVHDIQSQLKEAGQTPLRVPRCFHTSLEEFQEVIFLEDLRPKGFKMFDRKKGMDVAHTKLVLEELARLHAASYLLKAKIPDLTEKYPILKLDWLNYADDARDKTYKLFSKQMDIVKDMLNKVGGYEVAENWLGRNKVKVLDMLGDHIVGVPPFDLLCHGDCWNNNLLFRYNEEETPIEVMLLDLQLCRQASPATDLNYLFHSSLEGFVRKTNLESFLDIYYSSFLSVAEAGKTAIPFSREELRQEYKNNLEYGLLLAMLVTVIVICEGDINKEDEDGFTDSLKDVLDELVATSPILRPRFLSIFDEMIENKVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5F3</accession>
    <name>A0A423T5F3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002256">
        <property type="protein sequence ID" value="ROT71734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5F3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="678" mass="70357" checksum="96929CF280B0D8F8" modified="2019-05-08" version="1">MVASSSIQSAFSHLAPNSSLQSASSDLVVSSSDQSAFSDLAHSSFHQSAFFDLASTSSHQSVSSHLIASSSHQSAFSDLEPTSSHQSFFDLVASSPHQSAFSDLTANSSHQSAFSDLAAISSHQSVSSHLSASSDLAPTSSHQSAFFYLAPTSSNQSAFSDMAPTSSNRLASCDLVASSSHHSFHRAASFDLAPTSSHQSVSSDLEITSSHQSVSSHLVASSNTTSSTHQSAFSVLAPNSSHQSPSNDVVASSSHQSAFSDLAPTFSHQSFSDLVASSPHKSAFFDLAPTSSHQSPSSVLVASSFHQSSFSDLGASSSDQSAFSDLAANSSHQSGFSDLTASSSHQSASSDLAPTSSYQSASSDLATTSSQQSVSSHPLASSSDQSAFSDLTHTSSYQSAFSDLIWHAPLHTSDLLASASDQSAFSDLAASSSLQSAFSDLAAFSFHHSSYQSASSDLVASSSEKSAFSDLAPTSSHQSASSDLVVSSSDQSAFSYLAHSFFHQSSFFDLALTSSHQSVSSHLVASSSHQSAFSELALNSSLQSVSSRLVASSSHQISDLGASSFHQSASYYLAPTSSHQSASYYLAPTSSHQSASSDLVATSSHQSAFSDLADSFSHQSAFSDLAASSSHQSAFSDLAASSTHHQPSLTWQPAPLPASQHSLTWQTAPPISQHSLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7I6</accession>
    <name>A0A423T7I6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ADP-ribosylation factor-like protein 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009218</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002160">
        <property type="protein sequence ID" value="ROT72413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7I6"/>
    <dbReference type="STRING" id="6689.A0A423T7I6"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051649">
        <property type="term" value="P:establishment of localization in cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000412">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="118"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="228"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="390" mass="43099" checksum="B80E7FDAE2E13FB5" modified="2019-05-08" version="1" fragment="single">MRPESRVTIHFDPRRPPSQVIAVDTGGRRLVLQLLHTENCAGHFGRYRTLAFYQLLVWSSEAVREGSCDKRWSFTLDVFSCLCGVVKMGVGRVVEAAQSLVQGFVALLSAPAHIVLVGLDSSGKTTVLFRLRYGQYVNTAPTVGFNCEKVKSGGAHWLVWDVGGAERVRPLWRSYTRATDALVFVVDSSSSAERVEEARVELQRLSKQQVAECVAHNRPRPPLLVLANKQDLPGARDPQHLAKALGLPDLPECQPWAVAPACAVTGEGLDEAMAALHSLVLKTRKQQKSKKTGRVAARSHDRSHSPETTRRCVRTIASRECSQRNGPKGVPKVPPQKQRSDTPTWPRLEVISRACFFPSASALVAEDIARANSSTQHYRVEQDLNERVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8I7</accession>
    <name>A0A423T8I7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein phosphatase 1 regulatory subunit 35 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008861</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP1R35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8I7"/>
    <dbReference type="OrthoDB" id="6336882at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019902">
        <property type="term" value="F:phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903724">
        <property type="term" value="P:positive regulation of centriole elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045724">
        <property type="term" value="P:positive regulation of cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033590">
        <property type="entry name" value="PPP1R35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029135">
        <property type="entry name" value="PPP1R35_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28625">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28625:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15503">
        <property type="entry name" value="PPP1R35_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein phosphatase 1 regulatory subunit 35 C-terminal" evidence="6">
        <location>
            <begin position="95"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="238" mass="26845" checksum="B6421F49C90CD867" modified="2019-05-08" version="1">MQKKVVGGERHIYVKPSNGLDPSGARRKYPKEKPVLENREMRNIPIAPSLSQEIRNIAAQSSGALTIHGKRGKKKNHPIIPTPLPESAEGVYGEPELHSALRVSQALWKVRDEEPDLSMMLKEKLESPNTAARVKKQRAKRVNVSGSRQIFNDLVSVDVKEQELAAQFEDQLQMRATAVQPRARPRDPEPQLSDYLNVEDYITTCPITSIQVHPPFNSVRAHRVGREELCCLYGQLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAE9</accession>
    <name>A0A423TAE9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abhydrolase domain-containing protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAE9"/>
    <dbReference type="STRING" id="6689.A0A423TAE9"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="17917" checksum="13A69715F65066EB" modified="2019-05-08" version="1">MTPKQKADFAVIKFVAGLVLIVMRKFWFTSAAVMLGIFVLFWLYGGCLALLLTLIAFSGIVYQISDQLVYWPNFPPDSRVLVQPPSSMGLPAENLYLYARDGTKLHAVFVKQASGAVKSAPTFIYFHGNAGNLGHRLSNVYEMYRWLHVNLLLLVSTVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAM0</accession>
    <name>A0A423TAM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative vacuolar protein sorting-associated protein 54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008031</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002019">
        <property type="protein sequence ID" value="ROT73543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAM0"/>
    <dbReference type="STRING" id="6689.A0A423TAM0"/>
    <dbReference type="OrthoDB" id="6728797at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="113" mass="12586" checksum="BEC480D4B415B1A4" modified="2019-05-08" version="1">MSDTLERQFASWEARSPVPSPAFNGILKAVSKLHEAVSGVLPPQQMYKLFEKITSVLKEKLKVHLVRLNVSSVGPKSWVVTSELTFYFNHLESLGLGGLVSQEEFTSGLWPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB61</accession>
    <name>A0A423TB61_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative enhancer of zeste, ezh</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007808</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001998">
        <property type="protein sequence ID" value="ROT73730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB61"/>
    <dbReference type="STRING" id="6689.A0A423TB61"/>
    <dbReference type="OrthoDB" id="6141102at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035098">
        <property type="term" value="C:ESC/E(Z) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046976">
        <property type="term" value="F:histone H3K27 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045318">
        <property type="entry name" value="EZH1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041343">
        <property type="entry name" value="PRC2_HTH_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45747:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE E(Z)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18118">
        <property type="entry name" value="PRC2_HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Polycomb repressive complex 2 subunit EZH1/EZH2 tri-helical" evidence="3">
        <location>
            <begin position="186"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="220" mass="25243" checksum="C5CE7368EF1CA1FD" modified="2019-05-08" version="1">MSGRRKVSAEWKKRVKSEYTRLRSLKKFKRADEIKAAWNQNRAHLNELLEQEDQTMIGMGPVWVCSVEAPPHQAVMRRTHVTSSCSEPLSVPIRTISAVNPIPTMYTWAPLQQNFMVEDETVLHNIPYMGDEVLDQDGKFIEELIRNYDGKVHGDRETGFIDDEIFVELVDTLVQQYQEDGTDSSSSVGKRDFPCFAIFQAISALFPDKGSPEELREKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TC42</accession>
    <name>A0A423TC42_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001944">
        <property type="protein sequence ID" value="ROT74064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TC42"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="54088" checksum="FFB3056FD89080A3" modified="2019-05-08" version="1">MNSHTLTTQRARQRRKSDESNDKIEEREEEEEGNEDERSNKFSVSANRCVLEASFVNRSSPHHFYVLYNSAPENRTSSSTRHGYTFQSSSVHLTRPLLPPRPLSLFPRSLIVLHTLAPTPTVTGTERYIDPPLSAHGTNPIRLHTPSVLRFSLSPSSPDPLDLLPLYSTPPLQSPRPPLLSPHPFLPPFTWAPGKAFFLSQEACSPPALPKFPTRLPPPSLTYDAISLPLRLSLSATCLFYILVLSFCLFSSSLFLAFLFCVCVVSSPPFPSFVPLSFFLSPRPPLLSLPSSILSSLLLLRFLSLLISSSSLPSHGSAFSLALLLIPSAFTILIHALPHAHAPSPLPLSPSPASVLLCSSPPLISSPALRLCLLPLLSLPLALLSLPPSFSSLPPPLARPSLLSTLFLSRFLALPLRFLSPLVFRAPSALLSSLTHPLSLLSSPPPLCSLLSLLVSLSLTIYENYSWYHFNNIRVNQNGIVRWCNEKSLYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEV9</accession>
    <name>A0A423TEV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative ubiquitin-conjugating enzyme E2 J1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001826">
        <property type="protein sequence ID" value="ROT74976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEV9"/>
    <dbReference type="STRING" id="6689.A0A423TEV9"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000086">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="10"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="334" mass="36363" checksum="AD0FF4F20D310B14" modified="2019-05-08" version="1">MEASYNSRCPAVKRLFREAKELHEATEEYYAQPLEDNLFEWHFTVRGPPDTEFDGGIYHGRIIMPADYPMKPPNIIFLTPNGRFETNKKICLSISGHHPETWQPSWSIRTALLAIIGFMPTPANGTIGSLDYTAKERAKLAKKSQEYECPDCGCINSLLKERTGDNKDLQQEAREVMSQCAVSIKADTKNGSDQASGTADSSNTISKAEEADTEHSSLADGEDTTIAAETQGSANPESTVSAPQATNQTTLPGNHLANRNQGATAVDPAPEMLMEGVAPHNAQTNPVSSAPVSSPGFIYNMVLSAAIVLFIGLVMRRIFLLEGDTSEELDDLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG59</accession>
    <name>A0A423TG59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005973</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001772">
        <property type="protein sequence ID" value="ROT75480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG59"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="460" mass="48949" checksum="DB018E96CA9A78D3" modified="2019-05-08" version="1">MLCERRVEGGSALPPLRPPPLAPLPSLTILCFSLSLFPSLCFSCLFLLSSVPSSSASLLPSLSPLSSLSVPSSYPSPLPLSFFLFLFRSFIFLPPSPQHLSCPSFFSFLHSIALIPFPSIFAPSFPSLSPFPSIFPPSLLPRSPPITPSLPPPIPPSLPSSLLSSPIPSSPSPFPSLPILPFPSPPCPSPPSLPPLPPPPPPPPSPSRRKIPPGRLVTFTALETTPAAARRRPGRVASSSSRNARRPNGRPRTTPDSFDLRPTSRPPPACCVGSQGGTSSGEALLRPGLLALYCPEGAAPGPAFVPEESRRHRTGGYIGIFLPDIPASAMNILREPHFTAKGIGVSRILREFLPAPYLLPTLPPCFLLPIHPVLFFSPLSFPCAFLPLPPFRSPSHSPSLPCPFLPLSIPPSPSLSIPPPSPLPLPCPLPLFPLPPLPGPPRNPRRFSSRKKATAEEVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THC1</accession>
    <name>A0A423THC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">E3 ubiquitin-protein ligase parkin</fullName>
            <ecNumber evidence="5">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_005583</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the RBR family. Parkin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001721">
        <property type="protein sequence ID" value="ROT75873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THC1"/>
    <dbReference type="STRING" id="6689.A0A423THC1"/>
    <dbReference type="OrthoDB" id="1431934at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902532">
        <property type="term" value="P:negative regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009896">
        <property type="term" value="P:positive regulation of catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022603">
        <property type="term" value="P:regulation of anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20340">
        <property type="entry name" value="BRcat_RBR_parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20357">
        <property type="entry name" value="Rcat_RBR_parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16627">
        <property type="entry name" value="RING-HC_RBR_parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21382">
        <property type="entry name" value="RING0_parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1750:FF:000009">
        <property type="entry name" value="E3 ubiquitin-protein ligase parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000008">
        <property type="entry name" value="E3 ubiquitin-protein ligase parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047534">
        <property type="entry name" value="BRcat_RBR_parkin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003977">
        <property type="entry name" value="Parkin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054694">
        <property type="entry name" value="Parkin-like_IBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041565">
        <property type="entry name" value="Parkin_Znf-RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047536">
        <property type="entry name" value="Rcat_RBR_parkin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047535">
        <property type="entry name" value="RING-HC_RBR_parkin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041170">
        <property type="entry name" value="Znf-RING_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22605">
        <property type="entry name" value="IBR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17976">
        <property type="entry name" value="zf-RING_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17978">
        <property type="entry name" value="zf-RING_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037880">
        <property type="entry name" value="Parkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="21">
        <location>
            <begin position="17"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="22">
        <location>
            <begin position="305"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="93"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00029442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR037880-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT75873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="534" mass="58300" checksum="07EC57005FE022BF" modified="2019-05-08" version="1">MALFGFGSSQAAVSNELEVYVRTNTGEKVSVRLDQSWTVSQIKTTLAPKLQSPADNLRIIFAGKELPDDMVMRQCDLGNHSILHAVRVVSKEDEGKGAAGPSEVENVASSSNTQEDGVGGTEVTQTEKEDGRLQEVEVPSTSSGHTDAEVDLRSKAASPPLPEDPCLMPGPSTSNRSCGRLLCDASTVITIQMTEAEQKSIRDLKSYDGMGERPHFYVYCVVPCNSVQVGKLRVRCASCKQGALTLHRDPCNWEDVLQPGKINATCETPDCSGTQAEFFFKCRGHETSGEDDTSVALYLVRANLPAVPCLACTDVSSPVVVFECADAHVMCLDCFVTYCVSRLNERQFIQDERLGYTLSCPIGCQDSLIREVHHFKLMGDNNYERYQRWGTEEAVLAAGGVLCPYPGCGQGIIPDQDCRRVACLNGCGYVFCRLCLQGYHIGECNPEDGNGPNVIGNSGSFAVDPSRAAGSRWDEATSLAIRVTTKPCPKCRTPTERDGGCMHMVCTRASCGFHWCWVCQTEWTRECMAAHWFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIW9</accession>
    <name>A0A423TIW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative UDP-sugar transporter UST74c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001665">
        <property type="protein sequence ID" value="ROT76410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIW9"/>
    <dbReference type="STRING" id="6689.A0A423TIW9"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="2"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="272" mass="30488" checksum="1FE172E73BD5E04E" modified="2019-05-08" version="1">MTATVVVLFVAKRLKIVDYPEFSPDIVNKIWPLPLIYVGNLIFGLGGTKRLSLPMFTVLRRFSILFTMIGEKLILGNNPPFTIQLTVYTMILGSIIAALNDISFDAVGYFFVLSNNVFTAANGVYVKKKLDSKDLGKYGLLFYNSLFMLPFATSFSWFNGDLDKAMAYEGWSDLWFTVQFIMSCIMGFILMYSVMLCTQYNSALTTTIIGCLKNIFVTYLGMIIGGDYVFSIYNFAGLNISIAGSIVYSWVTFRRKDPPKPELLKAAPTSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIZ2</accession>
    <name>A0A423TIZ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Putative arginine-glutamic acid dipeptide repeats protein-like isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_005016</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001666">
        <property type="protein sequence ID" value="ROT76403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TIZ2"/>
    <dbReference type="OrthoDB" id="5843172at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04709">
        <property type="entry name" value="BAH_MTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11661">
        <property type="entry name" value="SANT_MTA3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000052">
        <property type="entry name" value="Arginine-glutamic acid dipeptide (RE) repeats"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1240.50:FF:000004">
        <property type="entry name" value="arginine-glutamic acid dipeptide repeats protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.490:FF:000023">
        <property type="entry name" value="Egg-laying defective protein 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002951">
        <property type="entry name" value="Atrophin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13859">
        <property type="entry name" value="ATROPHIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13859:SF11">
        <property type="entry name" value="GRUNGE, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03154">
        <property type="entry name" value="Atrophin-1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01448">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01189">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="13">
        <location>
            <begin position="99"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="ELM2" evidence="14">
        <location>
            <begin position="237"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="15">
        <location>
            <begin position="347"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="401"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="493"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="867"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="907"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1046"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1168"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="516"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="651"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="918"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="933"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1055"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1087"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1111"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1132"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1233"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1275"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1329"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1366"/>
            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT76403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1708" mass="184655" checksum="AC144557E9F07BC3" modified="2019-05-08" version="1">MTTTDRGKVVDQGEQGGGCGNASNTPPSSTASSNSNSNSSTNSIPPSGVLVPGGPRGPDGTVIEEVMTAVVGKKQPVRGQAFRAPNGEYVSYLCTDDTTLYRPGESVYIESQRADQPFFICSIQEFRRSKRDTLMVNIKWFYRPSEVPETVYQRLVQDRNTENNNKSLVTDDPVIKSRELFISDATDSYPVSVLRGLCRVDHYSDIHSVRDFNPEENAFFYILGYNPETRRLASTQGEIRVGPSHQAKLPEYRGNVMVEERPEVCADWEEQRWVPGASRDTDLLMYLRAARSMAAFAGLCDGGSTNDGCNAASRDDTTINALEMLHNSDYDHGKALQALVKCPVPDGIEKKWSEEDRKRFMKGLRQYGKNFFRIRKDLLPHKETSDLVSFYYLWKKTPAAAGHRPHRRHRRQNVLRRIRTPRAQRNTGPSDPLDPSSASEKDDDSDDSDSKDRQGYHCRHCYTTSSRDWHHAGKDKQLLCYECRIHFKRYGDLPVITNPREPPPGTGRPPPTPNEEDLRMRTRTRAKEISTRHRAVRRSRANTPDMTDECPTPDRRTPDRRTPDRRTSRHSASPAPKKGEDKNGRRIKRTRGSDDASGPSTPNKRKRNGGDISGLSSEESSDEGDGASGEPSSPSPATPSTPTPQLHPVSTPQPPTTLASAPPPVTVQPPRGSVVQAALVPTTVPRVSPSNLVPPPAHSGPSVQAQIIGRLPNPASPTQAPPVVTHIKPPIISSPPSITTVSSLINSAPNRPVITTTRVPPVSQLMSPGVSRPSSLTVVAPVASVGLATTAVATTTVTSAVRPVSTVPVDERGSVVRAPVSVPHSVLASVPPGTPPNAQEKMVKVKSEAEIVRYPPGIHPAMRHSYTQPGPAGLPLSQGPSNTTPVARVSPAPAIYSVGVSCTPPTSIPPVQTRSPIPSGPGIPQYPPGPVIKSEHIKREPEQVPRPEKPKYEPPPISALPSGPKLELGKVEPKQEIKSERGDRPEIIAEVKSEPRPDIKPPTTVGIPGIPSAAALASLPPNLAIPGYAYPYAPFGYPIPMQLPYGGQPTRPLTQRSQSPLQRPSSTGPPAPTAATNPSRLSPNPIPLTTGSSTITTTSTTTKPSPTLGVHPPPPPPHLGPPVYPSRTGGLPPHISSPSKLPSSQPSIVPAGIRPSVPAVGLPGMSPGLVPGMSQGMSQSMAHRMSPGMVPVTSGGPPPLPTPPAAHTGPVVKPPTMPTNLAPVPGPSPSQPPTTQALPATVQPSHPVYTGGPPPSIGSSGAIHDGDEQDDEDEAPQHREPSPEPKIEDSEFHRSESAIFLRHWNRGDYNSCTRTDLTFKPVPNSQLARKREERLRKQAEKEKEERERLQRKASTPDKRETPKPTSSGESSSIYGSMQPRNPVDTPALNRLSDYARPHAGLSPGAVRPPAIGLPPAMPSAPPPGLDLLHFGSMAALYPPGSQERMELEARERELRELREREISDRIKQEIMKRPMNPLDAGHPHSLSPHWISASRFPGFSPPVSLASGFAHGHGLYAPSPSASSAALLAVSERERLERLGLPATTLGLPAAATPSDNPLSVSTAERLALADHMHRMQLISEVHAHTHSHAHTHLHLHPGGMDVRPPADVTTAPSTTGGLDKHDDLNYLPKQRHLKVSANRTEVMVRNLSPLTWYEVSVISQNRHGSSLVPYSLRALTKAQEANKTEIVNPELPDIIGCCNEKGVKHYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLP3</accession>
    <name>A0A423TLP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative piggyBac transposable element-derived protein 4-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLP3"/>
    <dbReference type="STRING" id="6689.A0A423TLP3"/>
    <dbReference type="OrthoDB" id="8191242at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="1">
        <location>
            <begin position="51"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="179" mass="20126" checksum="28B3305634FCCF70" modified="2019-05-08" version="1">MTQDCFDQLRRSLHMVDNEGSHPPDDRLWKLRPEDYGRRVSLEISGALVAVTFNPSKCSRFRVKVFKLTVNEGQQGYICAFETYTGKDRGDIPASQRAVIHLMGTAGLFEKGYDLYTDNWYTSPTLFHCLQSRGMNAVGTVRATRKFMPTDLQVKAAEMWTVTARLQSCCACNGATGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLU9</accession>
    <name>A0A423TLU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001524">
        <property type="protein sequence ID" value="ROT77436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLU9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="421" mass="47165" checksum="769001C3C0126A45" modified="2019-05-08" version="1">MTSSDAEALIQKTNGIHREMCWLSVHLLLHRLPPSIFISSISFLLPSFILLHLLSSPPSIFISFHFHLLSSPPSIFISSIYFIFLHLLLSLHLLSSPFFHSPPFPFFFPSIFIPSISFHLPSFILLHLLSSLPSIFHLPLHSPLSPFFSSISFHLLHLSSISLSFFIATSFLLPFYLSIYFNISPSPSLSLYLSISFHLPPFIFLHLLLPFLFLLLPPFIPIFLQLPLSPYTSLSSFLTLHLLQLLSISLPILPPSSISLSLSPITSVSLHFSSISFLTLHLLNISPPSLPISFTNYRSSSSSLHLPPSILHLSLSPFLALYFNISHLFSRSIYLQSPASLAIYLISLHHPPSIPISPHPLPFPPIYPLLSISHHLSPVISISFLLPPKPFIYFNISPSLSIVLHLSLSLSLYLQSPHPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNZ7</accession>
    <name>A0A423TNZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative TBC1 domain family member 24 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_003139</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Synapse</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001424">
        <property type="protein sequence ID" value="ROT78157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNZ7"/>
    <dbReference type="STRING" id="6689.A0A423TNZ7"/>
    <dbReference type="OrthoDB" id="10065050at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF122">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN SKYWALKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0770">Synapse</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="8">
        <location>
            <begin position="301"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="TLDc" evidence="9">
        <location>
            <begin position="615"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="800" mass="90313" checksum="2BDF11D60BC5D60D" modified="2019-05-08" version="1">MHLFPLKGHARRLKAVKTVAGHPPPAGSVYIAPRLVFLSSWSWTGGVISNYRRALVRYTRSNAFVSTEEVPVEFGSSSYTMALVMCATRGVACRHDEGKNHPHRSRLTKRQQNQSGNQHHSRRQQKSKSQSPLRQYTEDSCDTPGYTDSVQHRYPEEQEILYDTSNNNDRNRLDLNNLKIVNGKSVHVPVSAYPKSFIQWPVDGSTKNKRIAEVKKQVKLLGELIKMTVGGGQHDESLADDKTPSNPPPFSDHVDMSRIPAYALVHSAEDGSQPKWDDIKELINAGKMKEAKIMVREADWSLASPVREELWKEMCRHHSTEKDFSDYYYWDTVKQIYGTTELSECHAQLPAFIDTHHTVSHCLSPRGVSACERVISVIAFSHPAITYAPSLYSLTSVLLHYMDETDVYNCMSVLVSGAQNKFITQTKVSHEATWRAAMILARKHIRGSFSTLSKFGVTQEQIEEGFQNWLWWILASLPLTHLVRVLDCFLFEGAKVLLRTALAIFHLFVKAVMNDSSMAASLPSRGLKEAICRFCQNIQVPTQKLLKTAFGIRGFSKSEITKVIVQTEMFLKSQRSMGGTGSGSGVPEVPTLTRSVSLEGLPTSETQADIQMMSHTLTIKELLTLWSWLPVRMTMHQPSLIYTTEEHGCSLTTFFQRVEKHEPTLICIRTVKDHVFGAYCSTAWEQRNLKDEFGNRQTYFGTGECFLFSLRPTVAKYQWVGISKQQQNSELSSVEHSSELFMHADSYMITIGGGNGQGIMLDQELRFGKTEKCNTFDNPPLTPDVDFEVKVIEVYSFANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRN2</accession>
    <name>A0A423TRN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001288">
        <property type="protein sequence ID" value="ROT79109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRN2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="622" mass="65461" checksum="D81ADA755E30A555" modified="2019-05-08" version="1">MMTHTTTQFALPPSEFLLPSPPPQGLSTLRTLNPGSLLPLALPPGSLSSSPSPRVSPPFAPPQGLSSPPPRPSPQGLILPPGRPRPRVVPLSFPVRPLPQGLSLPRPPHVSPPFAPPPGSLLPSPLPPPRVPLPSLLAPPPGSLLPSPSPQGLSPPFAPPPGSLLPSPLPRVLLPSPSPGSLLPSPLPRVSPPFAPPPGSLLPSPLPQGLSSLRPSPRVSPPFAPPSGSLSSLRPSPRVSPPFALPQGAPPPGSSSSPLPRVSLLPLAPPPGSLLPLRPSPPPPGSLLPSPLPQGLSSLRPSPRVSPRPSPSNPFAPGSLSSRRPFSARVSPPFAPPQGLSSLRASLQVSPPFAPPPRVSFLPQGLSSPLPSGLSSLRPSPWVSPPFAPPPWLSLSFELPPCVSLLPPPSPRLFFPLASFPSLFGSPTLAAFPSIGLVLLMDSLFPLDWLFPLASGVQLSARVFIFFLGSAFSLALRCSPLDRHFASRLGFVPGFDFPLALGRLPWGRCFSPRLALPPGFSPLPWVGSCPLGWLFLLGSLLHVRFSLPPGFSPPHRVAHPPWPSPYGEHFPLVWLFLLVSRPPPWVWLLPLGFLLPRWVGSSPWVLSSSLGWFVPSVFALLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRX9</accession>
    <name>A0A423TRX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative per-hexamer repeat protein 5 isoform X12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001272">
        <property type="protein sequence ID" value="ROT79220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRX9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="647"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="676" mass="71879" checksum="8B9007B858C290D2" modified="2019-05-08" version="1">MAPLKRDAATQTMAPLKRDAATQTMAPLRGTGHSDDGALKSDDAPLQRDAATQTMAPLKSDDAPLKRDAATQTMAPLKSDDAPLKRDAATQTMAPLKKGRGHSDDGALKSDDAPLKRDAAAQTMAPLKNDGALEEGRGRSDDGALKRTQTPTKPAPARRASTPYKPVLGSRRSLFLHILGSRRSLFLHILGSRRSLFLHILAAGEASSCTSSAAGEASSCTSWQQEKPLPAHPRQQEKPLPAHPRQQEKPLPAHPRQQRSLFLHILGSRRSLFLHILGSRRSLFLHILGSRRSLFLHILGSREASSCTSSAGRRSLFLHILSSRRSLFLHILGSRRSLFLHILGSRRSLFLHILGSRRSLFLHISRQGEASSCTSSAAGEALPAHPRSRRSLFLHILSSRRSLFLHILGSRRSLFLHILSSRRSLFLHILGSRRSLFLHILGSRRSLFLHIPAAGEASSCTSSAAGEASSCNILGSRKPLLHILAAEKPLPAHPRQQEKPSSCTSSAAGEASSCTSSAAGEASSCTSSAAGEASSCTSSAAGEASSCTSSAAGEASSCTSSAAGEASSCTSSAQEEASSCTSSSPSHPTGDAAIHVEPLPVTAHSAHSQSAATCPLIQPIRVSEKERPSSLARGHRIQALCTKHRVASTPNPTRTTSCQRQSSVGSAVRARRAPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSJ3</accession>
    <name>A0A423TSJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Variant surface antigen A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001241">
        <property type="protein sequence ID" value="ROT79447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSJ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="519" mass="57473" checksum="884A236B54BFEACB" modified="2019-05-08" version="1">MPSLSLALPLFPHPEELSTDLPSPSPSYVFEYPVPPRPLSSQAPPSTSLPSRRISHSDIDATATNEDSMDAQMNRPNPPGLPYSNIDKETEHIQSSDFPDTHPERTHSSDLPDTHAEHTHSSDLPDTHAEHTQPSDLPDTHAEHTQPSDLPDTHAEHTQPSDLPDTHAEHTQPSDLSDTRTQPSNLSDVHTEHAQPTDVSDTQTQGIRPPAQTGPSPLSDIQTESIQSSDHADGQNEHMSSALLDVQTEHVQILEFSDENPESPASEPQELESQENGSSENIHCADDQRVSPEPDLQSDLISVQTDALFLDRRSSEGTELTCSVQHADEEGVPKYMSEDIQMDYYESSVPPTARREPCDDPDSHADDADIPHDTRHPRMTQRHSIPGSDYADHQKETSKTHSLSKLLRAKTEPNLNTKSTKKHRVKPVKPKPKVKPRYRSRSSSPYTNSAFLPRLPAATSLSSPFPKLPKRYKGTARRRKISKDHLSPPTLFPKLASDAPPPPSYPQSLRPPQSPSIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTT7</accession>
    <name>A0A423TTT7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="31">Epidermal growth factor-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="31" type="ORF">C7M84_001418</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="31">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="31 32" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="31">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the neurexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001184">
        <property type="protein sequence ID" value="ROT79850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TTT7"/>
    <dbReference type="OrthoDB" id="430340at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005112">
        <property type="term" value="F:Notch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00033">
        <property type="entry name" value="CCP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="CDD" id="cd00057">
        <property type="entry name" value="FA58C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000368">
        <property type="entry name" value="Delta-like 3 (Drosophila), isoform CRA_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.70.10:FF:000014">
        <property type="entry name" value="Membrane cofactor protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000004">
        <property type="entry name" value="Neurogenic locus notch 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000173">
        <property type="entry name" value="Neurogenic locus notch protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000434">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000146">
        <property type="entry name" value="Putative neurogenic locus notch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000053">
        <property type="entry name" value="Slit guidance ligand 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.10:FF:000018">
        <property type="entry name" value="Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000309">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000472">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000649">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.10:FF:000032">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.290:FF:000048">
        <property type="entry name" value="Uncharacterized protein, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1220.10">
        <property type="entry name" value="EGF-type module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013032">
        <property type="entry name" value="EGF-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003410">
        <property type="entry name" value="HYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035976">
        <property type="entry name" value="Sushi/SCR/CCP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000436">
        <property type="entry name" value="Sushi_SCR_CCP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12916">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2"/>
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        </source>
    </evidence>
    <sequence length="3609" mass="394229" checksum="A6579184F2F8C935" modified="2019-05-08" version="1">MGGSQGFHKAQDSLNSLELLSPGLSLQPLDSLNSGLPPHWTPSLLDSHSWTPSHPGRPSPFVSFSSSDIHKHRNNFPFSLLRFGSDLVLVESYEQNNFTEHLAHQTLDHPTNSYWLGLVSLNDLSTNTLESAGGQHVSLYSGFWAQGQPKVTEGECVRGRLTDTHQSWELSTCETLLPFMCRVEACTKGAVHCSNGRCINKAFQCDGQNDCGDMSDEMDCPNQCNFYTQSSGESIESPEYPKKYGPNLDCKWTLEGPIGHNVILQFSEFDTERNFDTVQILSGGRTEDSAASLTTLSGRQDLTNKLFISASNFMIVKFKTDASVEKRGFRASWKTEPQDCGGELIATPQEQVMTSYNYPLEYPGGLECLYILKTQQGRVITLEILDLDLEDENDFILIRDGSTPSDAMLARLTGSQDENPKFIISTGPFIYFYFQTNLGVSRRGFRIRYSSGCSVTIEASKGTITSPAFGISDYPTNQECSYLIKRPGGGSLSLKFNAFDVEEKDAIQVYDGMTSSQGFRLHSGNGFSAKNPPSFTLTADSGAMFLMFNSDPLRPAAGWSANFSADCPKLNAGEGAIASLTDTSFDSVVTYTCPVGQEFANNKTSIVTKCMPGGFWSEDYIPNCQVVYCGPVPQIDNGFSIGATNVTYRGQATYQCYAGFGFPSGKPVETVKCTELGVWEKLPECLASQCPALPETPFASQEVLNGGGRSYGTVVRFECEPGYYRTGLPVIHCMSNGSWSGDVPTCSRIQCHEYPEIENGFIADVTRNYYYGDEARVQCHRGYKLIGSPIVKCGPEQNFVNLPTCEDINECEAAQCDAASTECKNTPGAFSCMCKAGFRPNLNCRPRGDLGLSDGGIPDDAISVSTTAAGYEKNSVRLNSQPGWCGAVPVPGRNWVMVDLRVPTVIIGFRTQPVGLTDGQLAFAKSIRLQYTDDLTDVFREYTNNDGSPVEFRITSGASLSVVNLPTPVEARYIRLTLADYEQAPCLKFELMGCARQDCTDINECEDNNGGCDQRCINSAGSFSCLCNVGYDLFTENGTAGYVIERSESGLRDGDTYRLNKTCVRKMCPALESPENGKLLDTRSMYHYGDLVKFHCNFGYVMIGSDTLTCTSNGVWNGTLPECRYASCTPLQDDPAQGLTINYASPDEPVVPFMSNVTVSCNVPGRPLRKTLTSGFRECVYDPQPGLPEYWLSGIAPQCPRVSCGLPAETPGATYGFFKDTLYETNFFFGCEETFSLAGQTSRFDNAVRCLSDSNWDFGDLRCEGPVCSDPGHPPEGIQIATSYEQGSRVSFDCTRPGYIPITDEPIRCVREPECRVVAPIGITSGKIPASAINATSERGNYEARNIRLNSATGWCGQQEAFTYVTVDLGKVHRIKAVLVKGVITNDVVGRPTEIRFFYKKQEGDDYIVYFPNFNLTARDPGNYGELAMITLPTVVTARFVILGIVSYDKNPCLKFELMGCEDEPAENRLLGYDMGYPVCVDNEPPQFANCPVNPIVVQKGPNGVQSVNFTVPTAYDNSGMIARTEVRPPGFRPPIHIFKDTMVEYLAFDFDGNVAICQINITVPDDIPPSITCPQSYVIELVEEQENYRVNFNSSLTLSSVNASDNSGEFTLKVMPEVALIRVGGYENVTVVATDPSGNSASCNFQVAVQATACVDWELKAPANGKLNCLPDQGEGVQCLATCDTGFRFTDNMAVKTFTCTEENLWQPSRMVPDCVSENTEQASYDVVADVMYRANGAVLPTCLPQYESLVQQFYESLNGVLSSRCSAAVNVAIDVMFHETRLKLVQENMVHVSYVLRITPEVKQKLLYDLCGSTLSLIFDLSVPSTSAVIEPILDLSSAGNACPPMQAQRSNVSRGFTCNVGEVLNTETSEVPRCLHCPAGTFARREETMCTPCVAGFYQDQSRQGSCKRCPPGTYTRTNGTKSSIECVPVCGFGTYSPTGLVPCLNCPRNSYTEAPPEDGFKECQACPPETFTHAPSTASQQMCRQKCRPGTYSDTGLEPCAPCPRNFYQPSIGSTSCFECSTGNYTDDEGATSSEMCLSVACSGVCQNGGLCLARQHQVQCYCPAGFTGQFCEVDVDECASRPCYNGGSCVDLPQGYRCDCSEGYSGLQCQDEVSECVEGTCPDRAMCKDDPGFGTFECLCRSGYTGVGCNITVNPCTEKGNPCANQATCVPLDQGRFRCECQAGWEGRLCEVNIDDCAEDPCLLGANCTDLLNDFQCDCPSGFTGKRCHVKVDLCQNSPCMNGVCVDNFFSHSCVCHPGWTGESCEVDIDECASEPCQNGGQCVDRVNGYQCACDTGYTGKVCQHTIDDCASEPCQNGGTCVDELDGFSCECRPGFVGLQCEASIDECISSPCNPVGTEKCLDLDNMFKCKCHVGYEGEFCEVNINECEPDPCHNGAVCTDGVADFTCTCQPGWTGKRCELDIGGCESAPCLNDAQCINLFEDYFCVCPSGTDGKRCQVTPERCVGNPCMNGASCQDYGSGLNCTCSEDFTGIGCQFEFDACEAQLCENGATCIDRGAGYQCVCPPGFTGRHCDQDIADCTSTSCPPGATCIDLTNDFYCKCPFNLTGEDCRKVINVDYELYINDESKASSASLATPFHLGMAPSFTVAMWVQFATSDDLGTFFTLYSVSSPYMPTDKKVLLQATNAGIAVEFFEDVKEFVTYRSNIPVNDGQWHHVALVWDGAEGTLTLTTDAVVVAQVEGFGQDRMLPMYAWVTLGSVESEFAGYTNERGFHGRIARLNAWNRALDFRTEIPKMVRSCMNSPVIFDGLLLRWTGYDSVKGNVERVGPSTCGQYVCPPGYTGDCSVLERDKTPPRVNHCPGDMWVITRNGSEVVTWDEPVFSDNIGVTQIVDKSGYSSGQAFTWGTYDIARVAYDAAGNSATCAFNIYVLEDFCPKLDDPVGGIQRCADWGPGGRFQVCKIECNDGLKFSQEVPDFYTCGAEGFWRPTPDPTFPLVYPACAPATPAQRVFKINMQFPSSVICNAAGQNVLSEKIRLALNKLNANWNFCTDTATSTGICNGLDVAVDCSRRSRLAREAVDVRAKRQATPDSDDVYDVKITFPSVNDGLSASRSRRETDQAYQYNLKVSFAAKNDPVQHSNAELESTVRRLIEGIILEKDEFDVRDALPNVVPDPSSLELNSEYSCPVGKVVVGSECVDCAPGTYYSTESKTCELCELGTYQNEMGQVACKACPQRAGRQGVTKIPGSRSAEDCQERCAAGRYFDEQMSVCRSCGYGYFQPDEGKFSCKRCDRGLTTRTKEAVSASECREECESGLQLGTTGPCEPCPRGTYRTKGIHSSCIRCPADRTTQGPGASSLEECSLPICIAGTFLSNSECLPCPKGYYQPEALQTVCLSCPQDTSTRDVGATSEEECSNPCEVHGEQMLCDSNALCLFISETSDFECRCKPGYNGTGEYCVDNCDNFCENNGLCKKNEDGEPYCVCSGSFTGSRCHLKSDFTYIAGGIAGAVVFVILIVLLVWMICIRATRRREPKKGFLAQPSTDPNGSQVNFYYGAPAPYAESIAPSHHSTYAHYYDDEEDAWEMPNFYNETYMKTGFQNGAGNSLARSNASIYGNKEDLYDRLRKHAYQGKKDKDETVDSDDQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUR2</accession>
    <name>A0A423TUR2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative structural maintenance of chromosomes protein 6-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_001098</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001146">
        <property type="protein sequence ID" value="ROT80170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUR2"/>
    <dbReference type="STRING" id="6689.A0A423TUR2"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19306:SF6">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="14">
        <location>
            <begin position="53"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="284"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="667"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT80170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1094" mass="126708" checksum="D55663F4B72ADDC6" modified="2019-05-08" version="1">MSVRKLDDLHNGDSEATPVSSQKRRRTSYSDSSYLTEMKMTQESASCGILERVIVKNFMCHDHLEFTFSPNINFVQGRNGSGKSAILTAVVVGLGGNVRATNRGNSMKELVKYGKYTATIDIHIKNVGRDAYKHDIYGDCIIVERKIMSSGGGSYRIKAKNGTVVSTKKDEIVRMLDHFNLQIENPVTVLNQDMSRSFLNSTDPHDLYKFFLEATQLQQMRDNYTYLQEALRSSLATIEGRKEDLPYLKKEVEEQRSRYEFSKSLADKRNKLRELRRELMWAVVREAEKEEEATVQKLEAHEALCNKLQEKITSYQTNFEEEQQQHKALQEELANRTNQLSNQAKETKAANEQMVKAKAMLKDQQMQAATAEKKVKSIQKEISELKEAIEKDNSAAQNNWAAQRAARLEKIENFKKEMLEIHQSMKTEDTHHSNITNTMEHKKAEQKQFFLEEKAIRTKCSRLEKELTELRGQQSNVFTVYGPWVPEVLKQIDIAHKKGMFSAKPVGPLGAFIKLRDQQWGHVAEAIIANRINSFCVNNQKDCLVLKQILSRVNFHGAPKPIITVSRFRERVHDVSQFEVQSDRYPSLWSVLNVSDTVVANTLIDQMQVESTLLIPTAQEAGRLLKDQRTVPKNCKVAYTLNRDIYHPDPNYRIYSGRGQQPARYLQVSVEQKISDLQAEIESTREELKTHSRKAQEYQAEMKELENEIHISNRKLQKDKVKIAQLRGQVRVLQDQEEPAPPDVSQLEEDIRQQEVLLESAQTHAEELKNLVIESKEKYQEASSKYEILRQEQHKFLQEAENIKKNVSQCEQRTNRLLQALEGYKKKKKETQTRKKDFEAELKEARENREKESERAKNFEPRFETTRSAKDVNSQYKALEARLSKEEAERGDPVEIAQKYKEVQQRYSGIIKALEGHSNLLELIQQSLEKRQQEYGCFRRFTSIMIKSYFRNRLSFRNLHGSLHFDFEKEILTMRVVKSGSKGDHDTVSELHKNKKSEKGAQQTLAMMSGGERSFCTVSFILALWEVMDSPIRILDEFDVFMDIVARKQSMDMMIDIADSKTQYIYLTPLELNKAEHPNVNIYRMPDPERREED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0N3</accession>
    <name>A0A423U0N3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024556</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000851">
        <property type="protein sequence ID" value="ROT82264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0N3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT82264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1043" mass="109651" checksum="E9EE86ADF1276393" modified="2019-05-08" version="1">MVLLAVKEGRELMESQCRREAWHQMCGGESLAPPVMRRGKGSWRALSNRQVVVNFSLARVFSVKPVVQRGFWSGSLATHGGFCSGSLATHGGFWSGSLATHGGFCSGSLATHGGFCSGSLAIDGGFCSGSLATHGGFLRRFSGILQRFLWQLTRFCSGSLATHAVSAAVSLALTAVSCSGSPGNSRRFSAALAAVSAAVLWQLTSNTASLAAVSAAVLWQLHGGFLAGVLATHGGFCGVLWQLTAVLLAAVSLQLTAAGRFSGNSRRFLQRFSGNSRRFLQRFLGSTAFLQRFSGNSSAAVTAVSAAVLWQLTAVSAAVLLFCSGSLATHAVSGGARGFCSGSLATHGGFSAGGFCSGSLAAVSSRRFLQRFSGNSRRFSAAVSLATHGGFCSGSLATHGGFCSGFCSGSPATHGGFCRFSATHGFAAVLGNSRRFLQRFSGNSRRFLQRFSATHGRFLQRFSGNSRRFLQRFLQLTAVSAAVLWQLTRFLQRFSGNSRRFLQRFLATHGGFCSGSLATQAVSAAVLRQLTGGFCGGSLATHGGFCSGSLATHGGFLQRFSGNSRRFLQRFSGNSRAVSAAFSATLSGFNSRRFLRRFSGNSRRFLQRFSGNHGGFCSGFSRRFLQRSLATHGGFCGGSLATHGGFSVLWQGGFCSGSLATHAVSAAVLWQLTAVSASSRRFCSGSLATHGGFAAVLWRRFLQRFSGNSRRFLQRFLATHGGFCSGSRQLTAFLQRFSGNSRRFCSGSLATHGGFCSGSLATHGGFCSGSLATHGVFAAVLWQLRRFCSGSRRGKRFNWAVSAAVLRATFLQRFSGNSRQLCSGSLATHGGSPATHGGFCSGFWQLTAVSAAVLWQLTAVSAAVLWQLTAVSGSGSLFLQRFSATLQRSLTLHSPATHGSFCSGSPATQRFSAGSFCSGLRQLTAASAAVLRAAVSTHGSFCSGSPATRSRQLTAVSAAVLRFSGATFCSGSPATHGGFSAAVLRQLILQRFSRQLLQRFSGNSRFCFSVFCSGSGRPATAVPAAVLWQLTAVLEQLTAVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U226</accession>
    <name>A0A423U226_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000778">
        <property type="protein sequence ID" value="ROT82760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U226"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019071091" evidence="2">
        <location>
            <begin position="23"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="495" mass="57932" checksum="E10B3BFEE4CF7626" modified="2019-05-08" version="1">MSSHSSFLLPLLSLSFPLPSSFSPSFVQTQRKTRETPKTPRNPKKPKKTPRNPEKAPKRNPPKKTRETPRNPPRNPEKPQEPPRNPETPRNPKKEKPQETPRNPKKPKKPKKPPRNPEENLRNPKKAPQETQKRNPKKHPRNPETPKETLETPETQENPRETQKPQKPRENPKKPQETIRENPKKPREPRTPKKPKKPQKPENPKKPKTPNPEKPQKPPKKQETPRETPRTPRNPKKPQETPRNPEKPEKPKNPKNPKKPQKPRNPRNPKKPLQKNKKPRETPNEKQNPENLQEPPQKQETPRKPQDPRKPRENPKKPKETPRNPEKPKKTPRNPRNPPKKQENPKPPKKQETPRNPRNPQKTRNPEKPQETRRNPEKPKSPRNPETPETETPRKETPNPKKKKPQETPRNPKKTKTPRNPKKPPKKTRNPRNPKKTPKKKPQKPRTPQKNKKTPRNPQKPPKKTPKKPRNKAPGVCLLHIAQRVADFRAKPGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U674</accession>
    <name>A0A423U674_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prostaglandin reductase 1</fullName>
            <ecNumber evidence="4">1.3.1.48</ecNumber>
            <ecNumber evidence="5">1.3.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">15-oxoprostaglandin 13-reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Dithiolethione-inducible gene 1 protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Leukotriene B4 12-hydroxydehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">NAD(P)H-dependent alkenal/one oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="36" type="ORF">C7M84_022599</name>
    </gene>
    <organism evidence="36 37">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="36 37" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="36">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="36 37" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="36">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="31">
            <text>(5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133974"/>
            <dbReference type="ChEBI" id="CHEBI:133975"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="31">
            <dbReference type="Rhea" id="RHEA:51213"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>13,14-dihydro-15-oxo-PGF2alpha + NADP(+) = 15-oxoprostaglandin F2alpha + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133374"/>
            <dbReference type="ChEBI" id="CHEBI:133409"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="27">
            <dbReference type="Rhea" id="RHEA:50590"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="32">
            <text>13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57401"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133408"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="32">
            <dbReference type="Rhea" id="RHEA:50586"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) = 15-oxoprostaglandin F1alpha + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50592"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:79072"/>
            <dbReference type="ChEBI" id="CHEBI:133411"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="24">
            <dbReference type="Rhea" id="RHEA:50594"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="29">
            <text>20-hydroxy-leukotriene B4 + NADP(+) = 12-oxo-20-hydroxy-leukotriene B4 + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51208"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57460"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133346"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="29">
            <dbReference type="Rhea" id="RHEA:51209"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="28">
            <text>4-hydroxynonanal + NADP(+) = (E)-4-hydroxynon-2-enal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:64736"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58968"/>
            <dbReference type="ChEBI" id="CHEBI:156112"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="28">
            <dbReference type="Rhea" id="RHEA:64738"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="30">
            <text>6-trans-leukotriene B4 + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51204"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:90723"/>
            <dbReference type="ChEBI" id="CHEBI:133974"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="30">
            <dbReference type="Rhea" id="RHEA:51205"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="33">
            <text>an n-alkanal + NADP(+) = an alk-2-enal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13737"/>
            <dbReference type="ChEBI" id="CHEBI:12834"/>
            <dbReference type="ChEBI" id="CHEBI:13757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.74"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="33">
            <dbReference type="Rhea" id="RHEA:13739"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>decanal + NADP(+) = (2E)-decenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:31457"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133455"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="21">
            <dbReference type="Rhea" id="RHEA:50614"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>dodecanal + NADP(+) = (2E)-dodecenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:27836"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133741"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="25">
            <dbReference type="Rhea" id="RHEA:50786"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="34">
            <text>hexanal + NADP(+) = (E)-hex-2-enal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50776"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28913"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:88528"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="34">
            <dbReference type="Rhea" id="RHEA:50778"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50608"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57461"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133309"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="23">
            <dbReference type="Rhea" id="RHEA:50609"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>nonan-2-one + NADP(+) = (3E)-nonen-2-one + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50616"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:77927"/>
            <dbReference type="ChEBI" id="CHEBI:133457"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="26">
            <dbReference type="Rhea" id="RHEA:50618"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>octanal + NADP(+) = (2E)-octenal + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50780"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17935"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61748"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="20">
            <dbReference type="Rhea" id="RHEA:50782"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>pentan-2-one + NADP(+) = (E)-pent-3-en-2-one + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50788"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16472"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:145276"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="22">
            <dbReference type="Rhea" id="RHEA:50790"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer or homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADP-dependent oxidoreductase L4BD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="36">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.48" evidence="4"/>
    <dbReference type="EC" id="1.3.1.74" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01000582">
        <property type="protein sequence ID" value="ROT84204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U674"/>
    <dbReference type="OrthoDB" id="809632at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047522">
        <property type="term" value="F:15-oxoprostaglandin 13-reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032440">
        <property type="term" value="F:2-alkenal reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006693">
        <property type="term" value="P:prostaglandin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08294">
        <property type="entry name" value="leukotriene_B4_DH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014190">
        <property type="entry name" value="PTGR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="15" id="KW-0379">Hydroxylation</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0644">Prostaglandin metabolism</keyword>
    <keyword evidence="37" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="35">
        <location>
            <begin position="15"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00031851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00033119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00047871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00047878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00047903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00048066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="ARBA" id="ARBA00048290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="ARBA" id="ARBA00048387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="29">
        <source>
            <dbReference type="ARBA" id="ARBA00048591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="30">
        <source>
            <dbReference type="ARBA" id="ARBA00048953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="31">
        <source>
            <dbReference type="ARBA" id="ARBA00049068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="32">
        <source>
            <dbReference type="ARBA" id="ARBA00049070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="33">
        <source>
            <dbReference type="ARBA" id="ARBA00049179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="34">
        <source>
            <dbReference type="ARBA" id="ARBA00049368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="35">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="36">
        <source>
            <dbReference type="EMBL" id="ROT84204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="37">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="332" mass="36415" checksum="1640CC0B229F745B" modified="2019-05-08" version="1">MVKARIWTLAKQPVGIPRKEDFSCIEKEVSECKNGDVIVEAEYLSVDPYMCFMAKKVPFGTPMIGTQVSRVIESKNPDLPVGSYVVAQAGWCTHARLPAKSFQIDNWFKRSEILIPLEPLPRSLGLGVIGMPGNTAYFGLLEVCKPKAGETVLVNAAAGAVGSTVVQIAKLKGCKVIAFAGSDEKVAWLKELGADHAYNYKTTSVTDCLSEAAPEKINCYFDNVGGKFTADVLPHMADYGRVAVCGSISNYTNDDHSDPYCDPVVKAKKLHIEGLNVNRWSDWTQGLEQMKEWVLEGKVKYRETVYEGFEKMPEAFIGLFSGDNIGKAVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6J4</accession>
    <name>A0A423U6J4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6J4"/>
    <dbReference type="STRING" id="6689.A0A423U6J4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019146076" evidence="2">
        <location>
            <begin position="28"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="571" mass="61179" checksum="6FB864D2AAEA72E5" modified="2019-05-08" version="1">MVLPPVFRPRRCLRLLALALPPPRVAAAGGGAASRSPSQVARFARAARSPAGSGPARPGPPSPRALRPPSARARPRRRPRLAGPPAAVPVPRSGARDQWPPPASPFCVARRGLLLCPPPRPLRSCPAFRFLAGRPSLRFSLPPDPLPRARPLAGAPWFPRVCRWAAAPPSFPSLVCGFPALFPGARPVLVALRAPPLLFLPLLPGPLRLRSVLFAVPRLLRCFRARLWAPCSLRVWRRGSVSSRPPPALVFAAPCPRVCAPVPRAPPVRGPPPGPCSPVAPRLLPLRVPACLCAARPSPRGPAPPRCLFSAPPAPVCSWARTTRPASALSARCAPSPAPAGSLPFPPADSRPACLGSPRPPPPLPGVPRPPGPLRRRSPFLLLLLSFLHLAPPLRGPVRRAAPVLRVALPAACPPPVPPLLCARLPPRDQPSDLTGPGSVRPSCWNREPKRRVASCRAYSFMASLKLQDSRLLSAQGCHARQTHGKPASGESRLNERERGPSKDWCDYGVFHGFVKEYDTSVLAVMCYEDDTSFWFFVLPGELVSGQGRPPLLSLCDDDAAVTAPLFLLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6W8</accession>
    <name>A0A423U6W8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_022389</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000544">
        <property type="protein sequence ID" value="ROT84415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6W8"/>
    <dbReference type="STRING" id="6689.A0A423U6W8"/>
    <dbReference type="OrthoDB" id="6381144at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT84415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="56187" checksum="AF380C15B5118799" modified="2019-05-08" version="1">MNEMIAYRAGVGGVLAASVGVTGILGLVTHPVSLGGPWALLALRVVQGAAQGLSFPAILRILEDIPESSRNVASLVTFLGPYLGTCLGVGLGSLEDWYTATYALGSVALVLLLPCLLLPPVEANVHQNLAWRRVLKSRAVWACLGVHVANTWVMHSLLVGVPFCLTYYLQQPCYRGWSAVAVVGAVAVICRPLEFLSPRLADKGPLSGLDRRRAPVLAGSLLVVTAVILMATIGLDSAGVLVGVAAGCAGVGVGLVRVGNRLNLEDLAPLQLWRLVHIFNLTGILTAAVVPVVLTAFAQAGKSGWMAVWLVPLTLVVPAALLHLFCLSSNAQSWDQPVTGYDGPAARPVRVSTISVAGWKAWVGVIANGHGPPKEIRRSLRSRQSFKSAKSALTYKTAMSRPRARSLSCRTVDDDLEADLKSVIEEASVECRSIAMESEVECRSVASTVFKSDCDDMFSAIEGTVGDVQRRDLPHALYNGTSLDRTTAWLSYHYCVDMPQRSMSVPGFPTKEETRRKNVVFALAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U741</accession>
    <name>A0A423U741_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_022317</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000533">
        <property type="protein sequence ID" value="ROT84502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U741"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="511"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="178"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="429"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="74"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="574" mass="66469" checksum="9FE50049965C0889" modified="2019-05-08" version="1">MMVTEVIMFDQMMEKINSLVAEVREYKEQNDDRLQRHEEALEHRMQEGTLDQEQPADSNLHQPQERELDQEDPVQQLRRQLEEHNRELEETRLQLLQMNAVPVPVVHTREQEIQELRRELEERNRELTEARQRLQGSGVAPAPMECAQDREIQEFRRQLQQRDQELAEVRRLAPSIQHTMTRCQDHHQQPPVINGSRSPPQPLPRSRPHTPVPEQQLYPERQHTYESQTSLLQQFRPRSSAQRPQSAHPSSQLSGTPFSYMFTKETVPHFKGDTSASQPLKKNQAIESWIRTIENIVKPATSEMFIQATRANCRGPAELIINSPLFDSITEWDTFKAALRSKFQGTYTSSDFYKVLYDIRMTPSQAPMDFFLQLEGHVYQGYRDHREAIGDPSELEKRVFLSGIPAWLQDFLSVKDGSPTQIAKTAQRIWNSRNGIRHSDTSPAKENPYHPNRPSRGRDLYAMPVATERSGPPYHRSPVRERWCEHHRVRTHGTSECRARAEILDPQSPQRRCYHCRGPGHLVRDCPFRERQGDQAPGTAGRFDRRSTLCGDITSQEGNGNDRAYQTASSGTQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U879</accession>
    <name>A0A423U879_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021901</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000474">
        <property type="protein sequence ID" value="ROT84908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U879"/>
    <dbReference type="OrthoDB" id="6380461at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019067236" evidence="2">
        <location>
            <begin position="21"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="207" mass="22334" checksum="7336992060B09257" modified="2019-05-08" version="1">MAWLHMTVAILAALAKSSHAQGSQGYIAPDPPCYAPTVTVYDTETQISTLVETVSTTVVENVVLTETAYVTETLTEREVQSVTEVETVVATETEEVIATAYETVYETQVVTQTETQVEERTAIVTETKVEEVEVTKCAAPAPPPRPAYGLSTSYGPPPRPSYKAPAPAPSYGPTPMLMSLGGFKGYPGFKGFDFQGFNPFSQYESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U880</accession>
    <name>A0A423U880_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_021900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000474">
        <property type="protein sequence ID" value="ROT84907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U880"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="246" mass="27127" checksum="8E6C489AC86CA833" modified="2019-05-08" version="1">MPPFLAKVPRDGRCKEGRGEGPDGEKSSGFNSAYVTEVAPSLVDARARVGGYIIIYNESLETCPTPPTHLGCYKCHKLLFQAVVPTQRCCLMDGHMEIRATMWASIIFASLVAVSSGIPQYSSPPPPSYIAPAPACDPVTVTETTTEYGEVVETTTVPVTTTNTLYETEVITQFETVVETDYVTETETNYQTETETQVIPTTIVDTQTTYQTVYETETQQTYITETTTAVQKQYKTVCPKNSYVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U935</accession>
    <name>A0A423U935_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Optix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_019921</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SIX/Sine oculis homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000375">
        <property type="protein sequence ID" value="ROT85218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U935"/>
    <dbReference type="STRING" id="6689.A0A423U935"/>
    <dbReference type="OrthoDB" id="3501850at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000046">
        <property type="entry name" value="SIX homeobox 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031701">
        <property type="entry name" value="SIX1_SD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10390">
        <property type="entry name" value="HOMEOBOX PROTEIN SIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10390:SF33">
        <property type="entry name" value="PROTEIN OPTIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16878">
        <property type="entry name" value="SIX1_SD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="264"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="266"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="286"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT85218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="36083" checksum="6C4EC0DACD9B4B5E" modified="2019-05-08" version="1">MIRARKVGGKRCHGDGRRAPNSEALLRERRGVAQRRSVSGGGDAKRRSRAKPRPPARQRHRAAATLESSPAVYPAKLASSVADLLRALQPNMALMSGLGGLGSFGSLGAFSALNALSASSAGTGGNVGGSGGPVVPTPLVALPSLSFTAAQVAAVCETLEESGDMERLGRFLWSLPVAHPHLHDLNKHEAVLRARALVAFHVGNFRELYAILESQRFSKPSHARLQALWLEAHYQEAERLRGRPLGPVDKYRVRKKFPFPRTIWDGEQKTHCFKERTRSLLRESYLQDPYPNPSKKRELASATGLTPTQVGNWFKNRRQRDRAAAAKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBH7</accession>
    <name>A0A423UBH7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_014319</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000028">
        <property type="protein sequence ID" value="ROT86051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBH7"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030667">
        <property type="term" value="C:secretory granule membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004500">
        <property type="term" value="F:dopamine beta-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042420">
        <property type="term" value="P:dopamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042421">
        <property type="term" value="P:norepinephrine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006589">
        <property type="term" value="P:octopamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1210:FF:000001">
        <property type="entry name" value="Monooxygenase, DBH-like 1, like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1210">
        <property type="entry name" value="Cellobiose dehydrogenase, cytochrome domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000945">
        <property type="entry name" value="DBH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028460">
        <property type="entry name" value="Tbh/DBH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157">
        <property type="entry name" value="DOPAMINE BETA HYDROXYLASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10157:SF23">
        <property type="entry name" value="MOXD1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03351">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00767">
        <property type="entry name" value="DBMONOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49344">
        <property type="entry name" value="CBD9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="DOMON" evidence="5">
        <location>
            <begin position="115"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="261"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT86051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="41666" checksum="514F1E13F5CB4152" modified="2019-05-08" version="1">MGAPHTAFLSTPSSPPLETPVDAAMTGSKASRRTERDRPRAPRQPSSRRIFRTPSSVALLLLRAPQPSLWCLLQTLVLTVSFLPGARCFAASSFATPRLSSYETWEHEAWLEDTGAFVVQWKPREDSIEFRVTARTKGYIGFGLSSAPRMDGADIVVGWVHSGKAYLQDRHGRGNVEPSVDEQRDWMLVGGYENDTHTVLIMSRPYNTCDKQDHVISNDTVRLLWAYHSDDPVDPESPRPRLHYHGAKRGVRSMFLLERGHRAPSHSRHTQDLPGGFSAHDAGLPPSRSPGLPPRFNAAGGHHHSHHHHHRAPLTRSWVLTNNGVEVDAASDTVYWCKVFKRPQLIQKNHVIRVSLGPPRSAPTPHKRFTCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LP64</accession>
    <name>A0A3R7LP64_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP-ribosylation factor-like protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_021779</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004634">
        <property type="protein sequence ID" value="ROT60684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LP64"/>
    <dbReference type="STRING" id="6689.A0A3R7LP64"/>
    <dbReference type="OrthoDB" id="442317at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060170">
        <property type="term" value="C:ciliary membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051649">
        <property type="term" value="P:establishment of localization in cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04157">
        <property type="entry name" value="Arl6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000457">
        <property type="entry name" value="ADP-ribosylation factor-like protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041839">
        <property type="entry name" value="Arl6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51422">
        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 16" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="15" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0519">Myristate</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT60684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="191" mass="21740" checksum="80EFFFD1095D70EF" modified="2019-04-10" version="1">MGMFDRLAFFLGLKKREASVLVIGLDNSGKSTMLNHFKTEDQKTTDIVPTVGFNVEKFKTKNVGFTAFDMSGQGRYRSLWEHYYHDCQGVIFVVDSSDKLRLVVAKDELDMLLQHAEIRHRRIPILFFANKMDMRDAVSSVKVSAALGLERISDKPWHITASNAITGEGLHEGVEWLTNQIKENFGNNMNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUU0</accession>
    <name>A0A3R7LUU0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_018476</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003406">
        <property type="protein sequence ID" value="ROT63629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUU0"/>
    <dbReference type="STRING" id="6689.A0A3R7LUU0"/>
    <dbReference type="OrthoDB" id="10027416at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026906">
        <property type="entry name" value="LRR_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366:SF171">
        <property type="entry name" value="LEUCINE RICH REPEAT NEURONAL 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13306">
        <property type="entry name" value="LRR_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018787053" evidence="3">
        <location>
            <begin position="25"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT63629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="337" mass="37231" checksum="4DA39C028E596F03" modified="2019-04-10" version="1">MTTTGGMLATVAVALAALLPLASSQEAMMCPTWEENPWCPCYNNDYGIFMECPMVSLDMVSKVLGLVTNPIHSLSIYDLDPNVTTLPSEVFSQSAGVSQLQISHSNLQSLADGSFEGLEGSLEKLTIKHCKLNSIPQAPIFQLGRLTNLDFENNNITEIPSFAFSKLTLVSLNLKDNRINLVSDYAFDGLKESLEVINFNGNNLSQLPLSSLRKLTSLKNLQVAFNRIPDVHLDEHNGLPTLQYLDMSSNRIRKIKSSSLSGLPELVSLSLYMNSINSVARDAFSANPLLETLFFSHNNIRHLARETFKYTPKIKTIDLGNNNMQSILGGLFMLLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWD2</accession>
    <name>A0A3R7LWD2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003168">
        <property type="protein sequence ID" value="ROT64926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWD2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="47705" checksum="EB40F2A8232547C1" modified="2019-04-10" version="1">MLPFSQSTSCIRLQRVIALVDGRKLSHFGLSEVGISLLLLPISLLRILSSSLIENLLSDTLSLSFSPPLSSLLCSLYSLSLILSLSLSLFSLVILFSLLSFSSRRLLVIALSLSCLAPATPRLMPDQDLSLSSLVYPPSSYFGSLYSISLSLFFCHLLAAQFAFVFFSFSHLFNSAQMLFFFYLSHLPMCHRASRAHYFYLSLFSLSQTTTIRSGLRPSSHSPEYNLCERSVSVTLFWSLFSSNTHTSSVFPLSSLSLISLSSTLSLVLSSLSLFSALSLLLSSLSRLLSSLSSSSSLSLSLISSSLPLPLLSLVLFFSSLSLLTLSLFLTSLSSPILNLSTSLCSSSLYSSLSLSLSLSLVCSTLYTRSLSHLALSLSPACSSLSLSLLSSLYSTLSLSSLPCVQSLSLSLLSRLSSLLGSLISLHIVRAISSSFSLSPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWN8</accession>
    <name>A0A3R7LWN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002924">
        <property type="protein sequence ID" value="ROT66498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWN8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="438" mass="49099" checksum="1F65DDA195D622F9" modified="2019-04-10" version="1">MSREEHERQKERERDQRERRKREEDRKRERKRMKRSAIPHPPVHPHRSPIHLPIHLRNPHPPQYLIHLFIRTVPHPFPYPLNEFLIHLFTRTVPHPFSYPLNDSSSTCSPAPFPIHLPYPLKRSSSTCSPAPFPIVSPIHLAIPHPPVHTHRSPSVSLSNLNASSSPAQPALSPIRLLIHLKPLIHLFIRTVSHPSPYPLSDSSSTLFTRTFPHPVPYPLSDSSSTCPPRHRSPSISLSHLTIPHPPRFLIHLSSAPSHPFSLSTLTPPHPPAHRIVPYPSPYPLKASSSTFSSAPFPILLPIHLTPPHPPRFLIHLFTRTVPHPSPYPLSDSSSTCSPATVPHPSPYPLCDSSSTCSPAPPCILPSPRRPHPSPYPLSEFLNPPVHPHCPPICLLIHLTPPHPPRSPAPFPILLPIHLTPPHPPVHPHRSPSFSLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXG9</accession>
    <name>A0A3R7LXG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-binding LIM protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003969">
        <property type="protein sequence ID" value="ROT61862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXG9"/>
    <dbReference type="STRING" id="6689.A0A3R7LXG9"/>
    <dbReference type="OrthoDB" id="1746725at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030032">
        <property type="term" value="P:lamellipodium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.950.10">
        <property type="entry name" value="Villin headpiece domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051618">
        <property type="entry name" value="Actin-binding_LIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003128">
        <property type="entry name" value="Villin_headpiece"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036886">
        <property type="entry name" value="Villin_headpiece_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24213">
        <property type="entry name" value="ACTIN-BINDING LIM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24213:SF9">
        <property type="entry name" value="UNCOORDINATED 115A, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02209">
        <property type="entry name" value="VHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00153">
        <property type="entry name" value="VHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47050">
        <property type="entry name" value="VHP, Villin headpiece domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51089">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HP" evidence="1">
        <location>
            <begin position="186"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="251" mass="27877" checksum="792ABA9A16722CFE" modified="2019-04-10" version="1">MPPMAATPANPTTTNVCPHLALSSNPNPTLPYIIVVSALRGEPKPGYGLKSSTLPAAGRNGGPAGMIFVSSLRQPPKPGYGFSPRNTFYRQGLGSYSALHGDYSFTGLGEKTQSTEFSSARSDVSAGSLTEADRSALVCIECSLRRARVDNAELCASTTYSSGLRGYTSYSPHLRRSLPNMHHMSSEPPKIYPAHLLFVSNYRLPNDVDRCHLERHLSDAEFEMIFHMSRMDFYRLPEWRRNDLKRRCKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYP9</accession>
    <name>A0A3R7LYP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tripartite motif-containing protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_019599</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003633">
        <property type="protein sequence ID" value="ROT62554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYP9"/>
    <dbReference type="STRING" id="6689.A0A3R7LYP9"/>
    <dbReference type="OrthoDB" id="295536at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF15">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="6">
        <location>
            <begin position="206"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="322" mass="34769" checksum="CC6268435BF1171D" modified="2019-04-10" version="1">MEEELRCSQCTGYYHVPVILVCRHALCLACAGALQKPAAPPARSEDEGSVAPAEDLHETSEVDKLSVLSDADSGVSCSSRPTSLVGAPEGGSSSDPPPPPPVYTIACPQCSVLTPTDEAGAQGLTRFKVLAAVVDKHLERYQVAEPCQLCDAATAPRPAQVFCDQCLVFYCGPCREACHPARGPLAAHWLVSVAEGRALLRARRREREGRCTHHPQEHVSMYCLTCRLPVCVLCLHHGRHHAHDVHALNAVTKTHKVSTDANVLIIQSTEFQPYFVSVNSFNMASGLPGTIACCQPKIGAEYQTVMGICQCHGKFRFENSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2C0</accession>
    <name>A0A3R7M2C0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003096">
        <property type="protein sequence ID" value="ROT65339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2C0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="641"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="731" mass="85939" checksum="F913D5E6869ABC9C" modified="2019-04-10" version="1">MRRLSRLAAAETPRARQKTPRARQKTPRARQKTREPGRRRARQKRGRRRAGPESQAEDPESQAEDPESQAETREPEDPESRQKTPRARQKTREPGRRPREPGRRPREPEEARQKTREPGRRPESQAEDPRARQKTPRARQRPQAEDPRARQKKKKRARQKTREPARRPRARQKTPRARQKTPRARQKTREPGRRPREPGRKAEDPQAEKRQKTREPGRRPREPGPQREPGRRPESQAEEEAREPEDPRARQKTPRARQKTREPAEAESQQKTPRASRRPREPGRRPQKPRARQKKSPRARQKTPRARQKKSPERARQKKSQRESQKRPQSRARRRPREPGRSESHPARQKPGPREPPRARQKTESQQRPREPGRRPETRIPAEPGRRPREPGRRPRRAERQKTESRPRQRAREPGRPRARQKTPRAGRREPGRREPGRPREPGRRPREEKPRQRESQERDRQRPESSERGRESQAEDPRARQKTPRQRPRESQRPESQAEDPRARQKEEPPREPGRRRGGEPAEDPESQAEEPESQAEDPESQAEDPGRRTREQAERGPESQAEDPESQGEESKTPRARQKTPRARQKTPRAKSPRARQKTREPGRKTREPGRRPREPGRRPREPGRRPESQAEDPESQAEDPRRARARQKTREPGRREPRARQKTPRAQKTREPGRRPREPGRESQAEDPKKTPRAEDPESQAAESQAEDPESQAEDPESQAEDAERSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M398</accession>
    <name>A0A3R7M398_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002265">
        <property type="protein sequence ID" value="ROT71686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M398"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018601983" evidence="1">
        <location>
            <begin position="21"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="251" mass="21966" checksum="B0E1334A02028B1A" modified="2019-04-10" version="1">MNPLSLRGVSVLVLVCVVSAAPQGYGAGGDGGLGVDLGGAGGHGGAGGHGGSGVGGGSVLPFVFVGSSVLPESAIGGVGGGAGGVVGGEYSAPAAGAAGGFDAGVAGGFDGGLAGGFDTGVAGGFDTGVAGGFDAGAAGGFETGVVAEEYSAPSAGAAGGFGAGVAGGFDAGVGGGFDAGVAGVGGGFDAGVAGVGGGFDAGVAGVGGGFDAAPVGAVDSGFVSDNIIPQDAIRSLPGAAAPAAEYAGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3C5</accession>
    <name>A0A3R7M3C5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002256">
        <property type="protein sequence ID" value="ROT71744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3C5"/>
    <dbReference type="STRING" id="6689.A0A3R7M3C5"/>
    <dbReference type="OrthoDB" id="6371339at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="147"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="435" mass="48861" checksum="C3228F059E556201" modified="2019-04-10" version="1">MLTDLYTKGRLYRVDLSPLLQPDLVERHQRDDPLWQQLIEYLEEGRLPPRRIPLPLDQFELRDRVLYHVKSNNERALLQLVIPRSLRGAALDAVHAVPSAGHQGVHRTYQRLRDHFYFPGMLAASRKYVASCTACQRRKGAIARTPLQSMPDVAEPFERVSVDILTLTPSARGNKYVLVLIDHLTRFVELFPLATKDAQTVADVFLAEFVTRYGPPRTLLSDNGLEFRNRLLSDICHHLQLGWPLVRPPERLVSVGPPITIEGGGLDRGSITKGIWSLCIAALSCTPVTEPDPWVPDEPQRDACCPLLITSPSCNITLYDLGPNTLAACSFQSLPFIQPVEWGIPLTMDGSRAQQPASVLRNDPVLSYSQPPLIYAGFLFCLRFWQGRAFVLNVCRNPVQLLFLLSLAKLWLVFTPDRQCPGAEVGLRSFPMTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M614</accession>
    <name>A0A3R7M614_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002085">
        <property type="protein sequence ID" value="ROT72982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M614"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="216" mass="23904" checksum="32E0AD85879B6152" modified="2019-04-10" version="1">MRGVAGLTFPACSISESGARDDPRTGLVGNATTLKHYDVSSQLCLRRVHRWQVGLKPRSVVTQSLPCRAVLAGHVTRCVTRVYKCGHTPGRSECGGRGRTFAVAPRSRQKTVDSSRGSASSRFQNTSFGGTLKMSLSRRWLWWAVLLAWAAVMCQQVSAAAAPLAYRPSACQDRFCCGATLETRNCRYQGQRCRCPFVVRKPYARPYWGSHQSEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9Q2</accession>
    <name>A0A3R7M9Q2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002372">
        <property type="protein sequence ID" value="ROT70904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9Q2"/>
    <dbReference type="OrthoDB" id="6343880at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038877">
        <property type="entry name" value="THSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16311">
        <property type="entry name" value="THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16311:SF3">
        <property type="entry name" value="THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="583" mass="63706" checksum="D3B4434D033B70D2" modified="2019-04-10" version="1">MTKSLTIFPLRNRTDAPLYTWDFENSTALLGNGTPEASSSSADDPLTLSLFAKGYRRAIKTYRVAENVANLSFVFPCGLVVQGGIHFFRLARGDAVLAESGEVDVAWPRVVMQVPRRLETYHSPVDVEFGFTRNICLPQSPVHFKVWVDLLYHGVPVAGPDLNPQPTTATPPGSGRRGKHRGGWTPLDDDRLRRALRKARNRTSAHDRKEGKSRRKFTWRMKKQRRRKNRLAGVARPDARQGETQDRDGGEEGEAEEALARVKRMMGAQPPRGTLVSSGARAGSSAWGGRAMRLERILLPALYARGSHRVSFLCDSIGPAGLYSVRLITNVSSSPVIASSEWFTVVWSDLFNLFIRASSITPCKVALGVTVSHPACIGEFDKVRVFARVRANVTSADPPTVDRYLLERRVIPFKSSVVFPCSVFELEATDFCFVYVNTAKNKAVSEVQRKCIPTYRPNGIIITIFIVVYRLRLGISPGPNQHPGQSTLGVQQKPGDRARLAPPPVALGSPRDPRPPPLALGSPVAHGSPPDSAPPVTLASLRDSPPPPVALGFPVAHGSSVTRPLVALGSLRDSPPRGSRLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBC4</accession>
    <name>A0A3R7MBC4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="9 10">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Eukaryotic translation initiation factor 3 subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_009549</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="9">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix. Interacts with mxt.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002209">
        <property type="protein sequence ID" value="ROT72090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBC4"/>
    <dbReference type="STRING" id="6689.A0A3R7MBC4"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001060">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000607">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="56"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT72090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="693" mass="80569" checksum="F6FF4AB6351DE607" modified="2019-04-10" version="1">MAKKKSRPLDNEDDGGAEEEEPDFSDPEDFVDDITDEELLGDLLRQKPKETDGVESVIIVDGVPCVGAERLEKLKNVIRKIFKEFGTIINEFYPTGEDGKTKGYIFLEFKDRSSADEAVRQRNNYKLDKQHTFQCNLFTDFDKYDNIPEEFVPPPAQPYKDLGNMHYYLLDDNCFDQYSIILDGGTTTAIYLNAVPEPVEIAKRERWTETYVRWSPRGTYLATFHGKGIALWGGEEFRQVSKFSHPGVQFIDFSPCEKYIVTFSPLVDQRAEEPQSIIIWDVRSGLKKRAFNAERPPVWPVFKWSSDDKYFARIVEDALSVYETPSFGLLDKKSIKVPGIKEFGWSPTDNILAYWIAEDKDVPAKVSLVSIPSREEIRTKNLFNVADCKMVWQKCGDYLCVKVARYAKAKRERNDIKYSGIYYNFEIFHMREKGIPVDSLEIKENIQAFAWEPVNNKFGIITGEPPSVNVLFFQVNKGQAPSELKRLEKRPCNNLFWSPQGQFVVLAGLRNMSGALEFVDTKDFQIMMSTEHFMATDIEWDPTGRYVASCVSWWGHKVDNAYWLWSFQGKCLKRHSVEKFCQLLWRPRPPSLLQSTDIKEIRKNMKKYAASFEVQDKMRFSKASREIIEKRQKQMSVFTEYRKRMIEQFESEKEQRLRLRGGQDTDTLTSNENDFEEEIVEFLIKKEVIPVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFZ5</accession>
    <name>A0A3R7MFZ5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 10">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_025236</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 10"/>
    <dbReference type="EMBL" id="QCYY01000950">
        <property type="protein sequence ID" value="ROT81609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFZ5"/>
    <dbReference type="STRING" id="6689.A0A3R7MFZ5"/>
    <dbReference type="OrthoDB" id="6359622at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT81609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="266" mass="29257" checksum="96E60773CF4A9867" modified="2019-04-10" version="1">MSSQRKFFVIGNWKMNVDKARIDNIVKFMSAASLDPNTEAVVGCPSCYLSYARQRLPDEIAVAAQNCYKVAHGNFSGEISPAMILDSGCEWVILGHPERRTIFKESDQLIAEKVAHAQQTGIKIIACLCETSEDREEGRTDDVLFGQMKSLASISDWSRVVIAFEALWASNTGVLATAAQVQEALAKLRHWLRANVSDKVANSTRILYAGSVSSSNCRELAQLEDLDGFLVGSAALRPDIVDIINARRPDVSSLIAHFDRPDGRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJI6</accession>
    <name>A0A3R7MJI6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Menorin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the menorin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000550">
        <property type="protein sequence ID" value="ROT84386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJI6"/>
    <dbReference type="STRING" id="6689.A0A3R7MJI6"/>
    <dbReference type="OrthoDB" id="413402at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019356">
        <property type="entry name" value="Menorin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21184:SF6">
        <property type="entry name" value="CONSERVED PLASMA MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21184">
        <property type="entry name" value="MENORIN (DENDRITIC BRANCHING PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10223">
        <property type="entry name" value="Menorin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Menorin-like" evidence="2">
        <location>
            <begin position="21"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00044953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="13003" checksum="96D3AF0062C9A93A" modified="2019-04-10" version="1">MATVGVKAVDVIDFFPDVGDDLSKITWGHAINDKDLLQSSIDNATIMMLEADVSPGRLIGQSPDDPHIPIMAHPPYETSNLSLEMWIDEVIKANENGKNKGAKLDFKSLSIVKYSLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML05</accession>
    <name>A0A3R7ML05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc finger, C2H2 type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_022343</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000536">
        <property type="protein sequence ID" value="ROT84466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML05"/>
    <dbReference type="OrthoDB" id="6362124at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000478">
        <property type="entry name" value="Zinc finger protein 133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001182">
        <property type="entry name" value="Zinc finger, C2H2 type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF139">
        <property type="entry name" value="HUCKEBEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="328" mass="36237" checksum="4DC6A2817ED74E71" modified="2019-04-10" version="1">MTDPPRPLSPTPIFRPWQPNLANLPISDQQKPQKFRSAHCSDKDRPPTSPMSSPGSLPVLPTPSRSAPPSQPAREPQKRRREDSEDEDVGSRRKVIKGEKGAPAPLTTPPAPFPVLGLRPPSLAIPTPTDLPRPREWRNKLRHAARGLPAGCAARPRPGALGAGSSRLGGNARERCARAVRGFAGVPGPLVPLLDMLVPAAEVERVCARRPRPKRFSCSECGSAFSNKGQLKGHLRIHTGERPFACGHDGCDKRFTRNEELTRHRRIHSGARPFPCPLCDKRFGRKDHLKKHVRTHQLHRRPLRGVFAAREKLFAWSPPVADVCDNSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQT2</accession>
    <name>A0A3R7MQT2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002794">
        <property type="protein sequence ID" value="ROT67594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQT2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="531" mass="60249" checksum="04EEF95D28635EBF" modified="2019-04-10" version="1">MFARDNLLLLASSSSWFPSLLTHSSSPSPGLYLLPFSFFLSFSSPPNVLLRLPFLLFYSSLLFGSSFSASFSFTSPAFIFFFFFFSLSLSPPVDVLLRLPSLLSIRLLLQVLVLLRLLLQLMLLFNLFLLVFLLFQLFILFLHFQLFLLFQFFLLFSFLFFQFFTLFLHFQLFLLSILLFLLFFLLFRFFSRDWSLVSPVVTSLPSLYSFLSPLFLSFFFFLSLLLILLSRRYFSSLSSLSTSFFLPSLTPLPFHLSLPSFFLPLPPSLLPSLLLSPFSHSFLSLSPIVLSPHFLLSLLSPSFFLLFLTPFNLTLPLLLSSLSLPPFVFLLSPTPLPFHLSLLSFFPPLFLPPSFFLLSLTPFHLSLPSFLLSLFPFPLLLSPFSHSLPFHLSLPSLLLFSLFPSPLLLPSFSHSSPSTSLSLPFHPPSFSILPLLSPFILVSHHFFPPPLPPLFPSVSSRLSLPFPSPSFSFLPLLSPFILGSRRYFLSSLFLPPPSFSFLSLLCRYFSSLSSLLPSFLSPFSHSSPLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MXN6</accession>
    <name>A0A3R7MXN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002200">
        <property type="protein sequence ID" value="ROT72141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MXN6"/>
    <dbReference type="OrthoDB" id="6362512at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="260" mass="29680" checksum="9C8E1A6835205E14" modified="2019-04-10" version="1">MAESLMGSDDSADEAPQFTEEEIEEAWWTDFTTSDFWTDEDNVDMLQAILDLKYNDYPGSELEADVEYFSNPRLVVYCLVCSNVELRSYKHFSTHVDGKPHKKKAAKSVYEDTCSTVKRLSLLPISKARMTYAEGTLEYELQRSSVPAIGMGFVFKEKYRGKIVYSCQLCSEARLDHDDMFKHLTCSSHAMEYIFVKFQKNVSLANLPVERSRVYECEGGVNFSIVDFSSHLPSKLQEASKSSSTLSPTRVSRLSLKDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N727</accession>
    <name>A0A3R7N727_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative melanoma-associated antigen G1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N727"/>
    <dbReference type="STRING" id="6689.A0A3R7N727"/>
    <dbReference type="OrthoDB" id="205198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1210:FF:000001">
        <property type="entry name" value="melanoma-associated antigen D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1200">
        <property type="entry name" value="MAGE homology domain, winged helix WH1 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1210">
        <property type="entry name" value="MAGE homology domain, winged helix WH2 motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037445">
        <property type="entry name" value="MAGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041898">
        <property type="entry name" value="MAGE_WH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041899">
        <property type="entry name" value="MAGE_WH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002190">
        <property type="entry name" value="MHD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736">
        <property type="entry name" value="MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11736:SF14">
        <property type="entry name" value="NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01454">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01373">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50838">
        <property type="entry name" value="MAGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAGE" evidence="2">
        <location>
            <begin position="42"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="253" mass="29030" checksum="3AF1C8E4BAF68666" modified="2019-04-10" version="1">MPRRRIVEDSSDEEPSQSQPASQLSQSQGGGEISDQDKKVLAGNVCNYFLVSDCKKIPAKRSDIVKSVLKDHGRHFKEVMAEANRIMERVYGYKVVELEKKNQFIMINTLMMNNQDDDDLLLAPTSNSEVANIGLVTAILAGIFMSGQVMQEGPMREYLKKLGIDIDSREEHPTFGNVTRYIHQDLVRQQYLQITLNKDVEPPSNEYRWGERAHKELSKKDILELVCKVYGNQTRPEDWVAQWKIVKKEEKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7G3</accession>
    <name>A0A3R7N7G3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative tRNA methyltransferase 112-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001263">
        <property type="protein sequence ID" value="ROT79274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7G3"/>
    <dbReference type="STRING" id="6689.A0A3R7N7G3"/>
    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21089">
        <property type="entry name" value="Trm112-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="18024" checksum="806E05B11C1E7C2D" modified="2019-04-10" version="1">MLTSKGIKNVKEGFPLKIQAEEVRNVDIDFDREFISRTIPKLDWNALIFAAQCVGHQEDLPETLPESYDNDEDLLKKLHHILLEVEVVNGCLECPETKRKFPISNGIPNILMILPTIVLLQVLRIQERLQELQLSVKSQTPDHRARKPQEARKSPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NQW4</accession>
    <name>A0A3R7NQW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003263">
        <property type="protein sequence ID" value="ROT64337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NQW4"/>
    <dbReference type="STRING" id="6689.A0A3R7NQW4"/>
    <dbReference type="OrthoDB" id="6356038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090263">
        <property type="term" value="P:positive regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14423">
        <property type="entry name" value="CUE_UBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000009">
        <property type="entry name" value="Putative E3 ubiquitin-protein ligase UBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024725">
        <property type="entry name" value="UBR5_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46276">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46276:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11547">
        <property type="entry name" value="E3_UbLigase_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="142"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="371" mass="40568" checksum="2E6155DE6A9F66FB" modified="2019-04-10" version="1">MTSLHCVIHPLPGTEDQLNERLKELGLRLNWSGGVGVSAVAGLRENIRQVAIGPSHIAVLTEDGRVARLVFSINTDALDLNKADHKQGNCNKSNNQSSTKLTARMSTGGRRIVRTTSGSGGVRGRGTGVIMGSSRPMLPAQYVPEELISQAQVVLQGRSRNLIIRELQRTNLDVNLAVNNLLSRDDEDVEEPEESGDSYVPEDLISLLDAGISVAADHPSVIIDADAMFSDDMFGYSSVRSRSGGSRGRAGERDREGSAGSGGSEHRADRELRWRDRHYSGPRKWLSNALLSVRVTQPPTEAGKKKDSLLPDAIDVADNLQYWPERLGNQPAPRFSHIAALHSELVAVSTSGQVYQWRWADKDPYVHPETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NSX2</accession>
    <name>A0A3R7NSX2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="11">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_016146</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01003021">
        <property type="protein sequence ID" value="ROT65868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NSX2"/>
    <dbReference type="STRING" id="6689.A0A3R7NSX2"/>
    <dbReference type="OrthoDB" id="10250191at2759"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT65868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="805" mass="90815" checksum="CDE6E3FD2D379E87" modified="2019-04-10" version="1">MAGATGMARRFLGGANERGAGRGGGRPGTTHTHIFPCPSTSPPAFVSSPNPLHLPQRPPAMSTRGALREPGARKSVGASPQVPRSRPEVVSSPPREGGDADGVLRAGPPPSREMARPERPSTAPINSLDLRRARAPRPLTVIKESTCYKTFSSCRGDTVFVIASPRVRLQQRLYTAMPEADYCKYASSLVPQPMRIPVNMQWLLQHCPVFPISGSKVRIITSPKEFYQELLDRASRSSHRISMSSLYLGTGKLEEELVSTMVKRADECKSLQVKWLLDFTRGSRGEYNSRSMLQPLITRHPSSCSVSLYHTPDLRGILKSLIPQRWNEVIGLQHMKLYVFDDTLVISGANLSNDYFTNRQDRYFVFENCPALANFYHCLIETVSKFSFLLHKDNTIAMPQESTVHPFLGNYKKYCSAMREAVEHLWRKECEKNVLRLQNVSQGHHHHLPSDKRGDDSNGEIEFRNMPDTLIFPTLQMGPFGITNDSIITNKLLTQAEEGARIQLASGYFNLTKEYMKCILYHSRATYGILMAHPKANGFLGARGFAGAIPAGYTQLAKGFYKRLCQERQNDRIFLCEYKQPGWTFHVKGLWYYQANKPLPLLTMIGSPNFGWRSVNRDLESQIVLITANEDLQKSLHQEQERLYNLSDQVTDKTFGQPDRWVPFWSESDVRITRSHIIPPHPFPLFPFSFSFPLLSYFLPLSPFHLTPSLPFPPLSLTFPFLFCYPLSLPNLLYSHSFLPMQVLQLPPPNSLLFLLNPPIFTTLIPFPPFFHPSLLPEPLSLSSIMGIHCLPLNDTSKTGIKADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NX19</accession>
    <name>A0A3R7NX19_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calcium-responsive transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002600">
        <property type="protein sequence ID" value="ROT69131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NX19"/>
    <dbReference type="OrthoDB" id="5984937at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029309">
        <property type="entry name" value="CaRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47456">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47456:SF1">
        <property type="entry name" value="PHD-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15299">
        <property type="entry name" value="ALS2CR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="63250" checksum="AFF7BEC43844F749" modified="2019-04-10" version="1">MMHEYAKEVKQEKKSGNSKIFKPFHVRKFKNLQEVYECLEDYQEQTVTHFIKYNRDKNFGNEEYVPNIEKGRIHYWSHTGKCGVPIEYDGVPFMHVGRWVLMCHQGQDTNKRHKEKYQIRKHIEQQESGVTPKSRNRTQVTKKVNCPAEIYVNHIMKFPQHKVPNALLAINSLPTDHMRKLAKKKIINSFKRYSNRFVRESWYYVRLPDPSAHEGHPVIGLVKQEPVASLAAEATIEISSQDGAPTTVKRKKTGKSTRFRTKEPVDPRVLQKMYELTRQGVSTVKMMQESIAEFVKEELFPFGEPPPTMYRRYNPTASDIQNAMYKVKQEMRLEGKSILQYRCAALVREITELVVQTDSEEYLNQLEEQLRNIYNAVRNTVPVQQVQFSKPEQEAEKGKRLLCESQLVAALPAEGEPKAKRGRRRRQMEHQTELEAATYHLKLENQQLHSGDQQMVLEGVQPTFYEEQQQGQVLEHHQVHEIIQREDGTITEVYYYQPIEQYEQYVKDDGTSHEQAQYQADTIIIEPQNIKTEPPQVENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3F1</accession>
    <name>A0A3R7P3F1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001906">
        <property type="protein sequence ID" value="ROT74367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3F1"/>
    <dbReference type="STRING" id="6689.A0A3R7P3F1"/>
    <dbReference type="OrthoDB" id="6750768at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000006">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000005">
        <property type="entry name" value="Aminopeptidase N-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF299">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="2">
        <location>
            <begin position="86"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="49230" checksum="7B448B6140F65EDC" modified="2019-04-10" version="1">MDTWTLQAGFPLISVGLEDGLVTASQARFLVCEENVTDPNEPLNSTLGYKWHVPLTYVTSANPKNETMHWMNLTDVEFEVGKEVKWIKFNVGQRGFYRVTYDEGGWDALIHVLQTEPHTLSPADRASLLDDAFTLVKAGTINATVALNLSLYLKRESLYIPWHTALNHLFSWVQLLFNYSAHTLMLEYIHTLILPHYERVGWMDTGTHIERLLRSEILMAAVECGNIQAIEEAQKRFAAWRNKNESIPPNLRSVVYKTGVRYGTEEDWRHCWQVYNTSSIPSEKSLMLKAMAQTRDPWLMQQYLEYTLDGSKIRPQDVMIVLSEVSQNPGGRLSAWRMVRQHWTQISQLFGHGSFTIGAIIKAVTSPFTSAFDLGEVESFFSNVDVGPGERALAQALETIRLHIQWHEHNLDDVTQWLHQQLSQPEGRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P4Q2</accession>
    <name>A0A3R7P4Q2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006139</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001785">
        <property type="protein sequence ID" value="ROT75328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P4Q2"/>
    <dbReference type="OrthoDB" id="6345657at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="143" mass="16339" checksum="C132D373B14EF219" modified="2019-04-10" version="1">MTVYAVYPEPTVHSGLYSADRGGFFDQVTPLEWHKIVYDNQSVAYSYYEKVFQIDADTPLDTVFLTTVGVTKSDNNYISLETKRSYDQTWQERGCAPLRTQEYQVVHYSTDRTTCRGKRMPTGPDPLTAKVTCEEGYRAEGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P875</accession>
    <name>A0A3R7P875_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001411">
        <property type="protein sequence ID" value="ROT78229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P875"/>
    <dbReference type="OrthoDB" id="6077994at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="873"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1100" mass="122615" checksum="AAE8F1C7FB6B6A8D" modified="2019-04-10" version="1">MRASVSAGPRERLVEAGLRRLERESSVSRRPWKRLSSAHAKRITGRRRMGLEKGARGVGRNAADQRRGHSRSNNAWHFISLALMVQGAWHFEGLSLVKRPQPSRRTYRPTCSSLFSTVLQDDEQRRGREGSLRRGDQKQTLAFRYAVESVNHDHGLRKTSLRPIIETIPPYDSFYASKRDKNPNCTANTRVESPRVEPAVSNPLSSQLQSPTVQLLIPIESRLTSNSLVVPNNPESESVTARQGTTRVEWPLTSVQRVCVATGGEVEDEGKIFIIQTRPCHPCGEAYLYFFSPELSSLLEGLHEAVSKLISASAADDVSLISDLSELSGALSSVVVLPQRLPDPPKMRKSTSVIDLAQIHELQPLCNIHTPTRLSSSQCNLAEELRGEPPLPGRLLGHSRRRSMSETNLAKLCLDETDEELESRDDDLEDADLRQADLPKDRTSSSGSYNSYRSTDSGVRLSASPSTHCDGGRYMSENAARRFVTKSDSIDSGVRTKDENREVAAEGDEAKKADPQAGDGKQESSSRRGMSALEEEPDVETKVGAWCLQSARARKSFFAKNLNVTCAAHKERKKGSLSRTMSESYKEVTDKHDEFRRLSEFTTSSKACTVYEEIVDVLKPLTQANQQAKEHDYEELDKCRRDIKRSYSFQEKTKPPPLPPRRPKSFSPDPWAEEALSKSGTLKKIFGLSFQSKSHSTESMLDVSSGYDDLSTLGSEDMAMVQALGTLPRVKKKPVDRRERQSSRSASPKMSPKQKGQRTPSTDSSLADASTPETPQQQQQQQQQQACQHRQYWRPEASSGPPGEPPDANLSTKFPNSYSMDSFAVDKGSQSCGTPVRDTDSDWADADVVPGSRLRSIPLRKLSSPQPPTDPSLWRDEGDCWKECDSRLLPGGFPPPPREPPPPPAPHEPHYANLPHHTHDQDYMSMDEVRGAYRRISSASVGEARRDSGGYLSMGEIRSFRAGDTPDCPGCSHAPGSITHHDCHPEREAMPEDHEYMTMDDIQTVLHTEFPGIYSSKEEKELYKHCGYKSAPASRKTSYSEGSDYLTPQEVGRMIRREVLAIRRGGREATPPSEDKPRPLDATLAHSAQRRLWTLTILWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCR8</accession>
    <name>A0A3R7PCR8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Solute carrier organic anion transporter family member 5A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002879">
        <property type="protein sequence ID" value="ROT66868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCR8"/>
    <dbReference type="OrthoDB" id="5062115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016323">
        <property type="term" value="C:basolateral plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015347">
        <property type="term" value="F:sodium-independent organic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043252">
        <property type="term" value="P:sodium-independent organic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004156">
        <property type="entry name" value="OATP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388">
        <property type="entry name" value="ORGANIC ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11388:SF76">
        <property type="entry name" value="SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03137">
        <property type="entry name" value="OATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="8">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="222"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="290" mass="31214" checksum="57D0053FD61FC01D" modified="2019-04-10" version="1">MFQCIRSIDLYRGCSGGCMCSQKEFVPVCVRDGPIRLTYFSPCHAGCPELEGTGPGSDFFNCTCGSPAASVTLGYCRETCSGFLLYNVVMIIIKTFLSVGTIGGILINMRCVAEEDKPLALGLKATMLALAVMLNPLVFGSLVDSACLVWEEVCGDRGSCWVYSSDDFRYKLHGMACAMFAVSVVFMSQAARHVGDLKLVEDAIPPSGDASSALSSGPPSLFSEFADGKEPAEGGKKEGGQGISDKDGRRERRRAEEVPQVPRNEVPMDFSRSRQHPHILPSNVIKTTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEH1</accession>
    <name>A0A3R7PEH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002689">
        <property type="protein sequence ID" value="ROT68330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEH1"/>
    <dbReference type="STRING" id="6689.A0A3R7PEH1"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="156" mass="17292" checksum="31B34C7104D5CB1F" modified="2019-04-10" version="1">MSAANGSVCVKDEVVYLFVHNHEGSQPRSNPSFPRPLTEIICHCHRDIFNINHDYWGNTLSTIAKTDAVGLVSEINEKHLVPWAAICSAGGLDNTPLTPYIDQNSVHPNHLHLDGSKLRKEGFTFSVPKPSQDNLMEVLKDFIGMKMFPANALPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF96</accession>
    <name>A0A3R7PF96_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fucosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_017611</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus</location>
            <location evidence="1 12">Golgi stack membrane</location>
            <topology evidence="1 12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF96"/>
    <dbReference type="STRING" id="6689.A0A3R7PF96"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008417">
        <property type="term" value="F:fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11660:FF:000002">
        <property type="entry name" value="Alpha-(1,3)-fucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11660">
        <property type="entry name" value="Glycosyl transferase family 10, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055270">
        <property type="entry name" value="Glyco_tran_10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001503">
        <property type="entry name" value="Glyco_trans_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038577">
        <property type="entry name" value="GT10-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48438:SF1">
        <property type="entry name" value="ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00852">
        <property type="entry name" value="Glyco_transf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 12 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fucosyltransferase C-terminal" evidence="13">
        <location>
            <begin position="18"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT64428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="218" mass="25394" checksum="83022630235D3C9C" modified="2019-04-10" version="1">MYESLGERKIGRPTAVMRNKTRLIAWFVSDCNSMSGREELVKQLQKHVTVDIYGACGTLTCIRGQSDCEGMLEKKYYFYLALENSLCEDYITEKLYYTLRNYVVPVVWGLGNYVKNAPPHSVINALAFPNVTALANYLIYLKNNHTAYYEYFLWKRKYKPVIRGDILRNAMCDICERLHTDNTTKVYKDIHWWFSPERQCLTIENPKIAAFLGRQNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG58</accession>
    <name>A0A3R7PG58_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integrase core domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002394">
        <property type="protein sequence ID" value="ROT70728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG58"/>
    <dbReference type="STRING" id="6689.A0A3R7PG58"/>
    <dbReference type="OrthoDB" id="6378979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681:SF1">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="96"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="44745" checksum="86901907D908D84D" modified="2019-04-10" version="1">MLCREGQTSLYLERVKIPNSCDDLLCDVSLGYPRPYIPPSLRRRFFDAYHQHRSNRATQHIIRSKVVWPAINKDVRQWCRSCIECQRNKIHRHTKSPLQPFPIPDSRFQHVHIDIVGPLPMDDGYSYILTMIDHFTRWPEATPIRDITAATVAKTFFNTWISRFGTPETVTTDRGAQFESGLWRHLMILLRSKRIRTTAYHPCANGMVERLHQHMKQALTSFSPNRRWVDQLPHVLLNIRTSFKEDLQCTSAEMVFGTTLALPADFLVTASNFEPGTFGKQLCERMARVRSRPTRPTRQQYIYMPAGLQDCSHAFVRKHPRPPLCPPYEGPFPVIRRGDKTITIRRPKGEDTVTIDRAKPAHLQQPFRIARVRFATAKLEGECCSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGJ8</accession>
    <name>A0A3R7PGJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010572</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002341">
        <property type="protein sequence ID" value="ROT71124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGJ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="654"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="702" mass="77572" checksum="61F2477D8D2B6CD7" modified="2019-04-10" version="1">MLVDFLPLLPLPPPLLSSPHHLQPPEGPSARPGHGLTPAPPAKSGPDPPRAPSPPPRFHLDAGVPGHEKPSPDSVASSRDQHTMGSLPYPYPLPLPISPPPLLPLFNSPFPFISLFGYFPSPTTFSRLILPFTPLLPILTPLSPFNSPLPLIPFLRPSLLTLTFYPSPFLFPSSSFSLLFLFLTPLFPSHISPLPLSFPAFLTPPLSPFTTSSLSLPFPILSPVLLPPPLSFLLPRFILALLLFPLSYSYLSYLPLPFPLPPSLVLYSLYISPYSSTSYPSLTILIHFLRPPPSPLPLSSVFISSLFSFSLFPLPFPPSHLIFFLPFPIPVFLPLPFHPFLSPSHSPFPLPFPFPHFSPSPSTSPLPLFSPSYPWPLPFPHLSLSPFPFPLPHPRPPTPSLPFPHFPLPFPTPTPSPPPSSYPSLPIHSAPSLSPFTLPIHLPPTPPLPLFPTLRDPPPLPLPLSPTPLHSFPPSHPPPPSTPPLPHLSLSSTLFLPIHPSSYPCIFHAYIYPSFALYSSLLSNFPSLLVHPFSFYLSSLTPILFPNLFPSPSSTYPSPSRFSSSSFIYPIPPFIILFPRLSSYLIYPPPPTLSILPTYPYPFVHPPSHLSIPLTYLPHLSFHFCLSSSSTIYPSHLSSLFIYHPSPLFILPTYLPFSFIILLLCLSFPPILLLLFVLLLPIPPFRSLKWAYPSPFFPLASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ76</accession>
    <name>A0A3R7PJ76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Xylose isomerase</fullName>
            <ecNumber evidence="2 8">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_007987</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="2 8"/>
    <dbReference type="EMBL" id="QCYY01002017">
        <property type="protein sequence ID" value="ROT73593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ76"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48408">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48408:SF1">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0859">Xylose metabolism</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="211"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="403"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="221"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT73593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="630" mass="70005" checksum="4F958C9CCA5B04C5" modified="2019-04-10" version="1">MGPQDSKHWTPPMLPGSKIKRPNLTSLDLLLLPLSQTIYYLPILALPLPFPLSFPLPSSTFSHPPSPFSSLPNSASPSVPLAFPLLPSSPSLFSLPPPLSITSPSPQTIPTFAPLTALPLSILPFPPTSSTSLAPHPHLPLPLPSSSFPSLIHPLPSPFHPLPPPPSTLAPPLARPLPHPSPSFPSNPPLSSPFLPFIPFPHLSSPSFPILTFPPTSSPSSPSPSPIPPRPPSTPPPLPPPPPPHSPLCPHPNRPLFVPGISPIQYNPDAAPDESLVFRHYDAQQEVLGRTMEEWLRFSVAYWHSFRGTGSDPFGAGTIRRPWDDGTESLENAKRRLRAAFEFFSKLGNKYWTFHDRDLAPEGATIAETNANLDQLVELAAELQKKTGVKLLWATCNLFAHPSNQKKRSKRNQQDDSPQVHARRRHQLRRPRDGLRGAQVKEGAGGRPRLGAENFVFWGGREGYLSLLNTDVKADLDHLAAFFRMVIVYKEKIGFKGQLLIEPKAKEPTRHQYDYDAQTVMSFLHQYGLTQHFKLNIEPNHTTLAGHPHEHDVVFASAYGMLGSIDANTGSPDLGWDTDQFPMDVRNCTVIMKTVVEQLRDSFDWIHDDVWIDIFLRLSRWTPREYEKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJW5</accession>
    <name>A0A3R7PJW5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronosyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007278</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:132367"/>
            <dbReference type="ChEBI" id="CHEBI:132368"/>
            <dbReference type="EC" id="2.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.17" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001921">
        <property type="protein sequence ID" value="ROT74228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJW5"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000050">
        <property type="entry name" value="UDP-glucuronosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF159">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 4 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018378417" description="UDP-glucuronosyltransferase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="460" mass="50201" checksum="FAE209582C08CC4D" modified="2019-04-10" version="1">MRVLLTLLLAAALAEGSRVLMVLPLGSASHKNILTPLAERLAQRGHQVTIASLHASAAPANGSALPFTDLVAADAWDVVRKVTGGFDVFRMREASGGKDVNSQVMKKVVRHLPEYCDAFLRDPALQAAWAERPDLVLLPAFMNECGLAFVHKFKAPFIYVTTSGLTPWTADLLGNPENPAYVPNQYLPYDTHMTLWQRTLNTLVRFISPHLRSQLVLSPWTAWSSGSWATPQCPCPSLGSAIRSEQLPASVRDTLVRAFARLPYRVLWKWEGAAVPGLPPNVLTRPWFPQQDVLGHERVRAFLTHGGLSSMQEAVYHGVPVVGLPLMSDQHLNVRQAVTLGLGRELTLETMTEDDLVEAITAVVEDDGFRTRVRARSLMLRDQETTPLARAVYWSEHGVQAVRRQGPASPVEPRQGGVAPPARGGTPISAAPHSPPSTLTDVTTHHCESPVNTVMAAIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PK49</accession>
    <name>A0A3R7PK49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative GPI-anchored protein PB15E9.01c-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001891">
        <property type="protein sequence ID" value="ROT74463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PK49"/>
    <dbReference type="STRING" id="6689.A0A3R7PK49"/>
    <dbReference type="OrthoDB" id="21678at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052237">
        <property type="entry name" value="Ataxin-7-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013243">
        <property type="entry name" value="SCA7_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15117">
        <property type="entry name" value="ATAXIN 7 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15117:SF24">
        <property type="entry name" value="SCA7 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08313">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51505">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCA7" evidence="2">
        <location>
            <begin position="535"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="987" mass="101657" checksum="F7F9D183222FA78A" modified="2019-04-10" version="1">MAALDDSLTHFEGQKWSLLAERLGMNSPTSDSEDEENTKVRRESTTTRLKKEEMAIYGYCPRWEDFYLVVCDVCGRAVKPQALKQHIELRHGGLSNPVKSSGGTKSSASSGSKPSKTRNRAHTINPVVKLEGRIDSRVLPDSPVCDLLSSPSGLALSQLKTEVKTEESLDSGPTLVPPPQPLPTSLPPPAPPEPQHPMPHPISHAGPPPSVGPPSIGPPSVGPPSVGPPSVGPPSVGPPSVGPPSVSCPSATHPSLTTYSVPPVTMSGTALAGVHIASQSVSSVEEEVNKISAMLQAEAEALTASQNLIASSNMDMGTGIVGTHDIVEAQGLAGGSVTSNGSSLSAGPGGMISNSQAMGSVPVPMSHMSMATLNQIQADLLATVSESDLNAVLNATPDSSDLAQTVLPNNSQCYLNESGGQQWAGVTAGGVTAAAKLHPAPSPSPGATGIPVGNSISAAPTLGTTATSQGITVVIGAGAQPSVTTVTTQPSLSMPTLAATLKKPVVSNTTLTPVPPTPSPKKSNKKKKPGERKLLPLKDREYDPEVHCGVVVAETGKPCTRSLTCKTHSLSLRRAVPGRSKKFDDLLLEHRAAKEAQTRAAKPPDAAAGQIQGTPPRGPAMATTSSGGMVVGGAAATSPLLVKTLGGSAPTLVAAGDPSPNPTLHHPMDPPSTPSHIHATPPSPAYWPPTPRIAPALVPADNFYVREPPKPLATCSYNCRRLGGHLATDHRADLLRSAFRNALKKPHPASVLSDSSISNTLNIGGTQERFVNVKPLLAKKLQLTVPSGSASKDGISVSTGYNGHIHVGNSMGIVNSSALAATLKRPTQPDALKNNATPITSAKNKNKKVKTNDGAINIVGNVLQLDTGGSKNHIPVVVSLQNGLSNTQTITLSNVAIAGVRNSTTQPIRINPSTTTTLVRDAQVTDARPGSSDSTNIVLGSSLPSGIVISDALAKSFKSDGAGSIRLELHSNTFGDASRLVTNTAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKF9</accession>
    <name>A0A3R7PKF9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKF9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="54286" checksum="7C3D5797821B53CD" modified="2019-04-10" version="1">MSSFGLLSRTPRSLSVICQALVPCHVLLFLLSSPLPPLVSFLLVSSSPVSASSFSPPLPLFVSLLILVLQFGLLSRTPRSLSVICQALVPLHVRLLFLLSSPLPPLVSSSSSRLPGVNSLVLQFGLLSRTRSLSCQSYARPSFRARALFLLSSPLRSLLLSSPLPPLVSLPPLAPLPPSLLFPWLILVPPVRTPLPDIAVAVSHMPGLVPCLVPSPLPPLVSASSSRLLFLLSSPLPPLVSSSPSRLPGVILVLQFGLLSRTTAVAVSHMPGPRSVPRAPLPPLVSSSSSRLLFLLSSPLPPLVSSSSSRLPGIILVLQFGLLSRTPRSLSVICQALVPCHVLLFLSLLLLPLFVFLSSRLPWRHSRPPVRTPLPDNRGRCQSYARPSFRATCSSSSSRLLFLLSSPLPPLVSLASFSSSSSDSSPGHRGSLSVICQGLVPCHVLLFLLSSLASSSSSLFLLYVFSSLVSLASFSSPVRTPLPDTAVAVSHMPGPRSVPRARQRRFSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PR43</accession>
    <name>A0A3R7PR43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Putative dynein heavy chain 5, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_007058</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001898">
        <property type="protein sequence ID" value="ROT74439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PR43"/>
    <dbReference type="OrthoDB" id="6334149at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000003">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000543">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000003">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000003">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain tail" evidence="15">
        <location>
            <begin position="19"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein axonemal heavy chain 2/5/8 coiled-coil" evidence="18">
        <location>
            <begin position="665"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="16">
        <location>
            <begin position="848"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="17">
        <location>
            <begin position="1378"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="17">
        <location>
            <begin position="1625"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="19">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF25007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT74439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2022" mass="231888" checksum="C0B98CB54367D0D4" modified="2019-04-10" version="1" fragment="single">IAPHGNRFERIGEVVPQLDVTGKYKRILARFHQELEKVTKIYNRQCENPPQLRGLPPVAGKIQWARSLFLHLEEPMMFFKDHAVLLKMPEGKEAVRKYNRIGKTLVQYELAYYDAWRKQSISDIQKSLRCTLVVRRPESEELFVNWDPRISTLLHEATKIQQLGFEVPYMTQLLLNRAPLLLKKRDMVKHLLNEHERVLSKVSKNLVNLLVPHVTTLKEALDPLLTTLTWSSIQAHSYFEQGFAAIRTFETLIDRVNDIFQHRMEGVLGAMTGVRLYALPDVNPWTLDTFVHNNWLTCCQAAQELNSRSRVVEDAVLELIELVLVGVDGGAPVEPGQCQTSFLTVDDLDDGGDFDDGRSVSSGGGSSRRSPVPVAEGHFTATLELPAKPLTTQEKAVRKKKEMREKVESAARDLRRNYHRRVLDVLIKSVRGALESIRKHTSVVPPLSKLNEASIRRSNDRPEDLGIALVELSVSLVSPGVQVSPSLDQVQEAINKVAKIILSTAKGVSQWIRCRKEDAAQPKLETEDSIGGRKSRKKVIVYEVPAMPKNYYTHVLESKDVSKVMSHMSNSFQSTRNEVHNTFNIWEQYHHLWRVDKDAAIKEFISLAPSVQDYDKTMKSYIVLEKQINAEECHYRVGALALNTENLKKALAEEASLWVDKFGEALKVNYMKEMERLFAQLNELSRRLERPLKDLDDIKGAIDILRKTRDLELDMDDAIEPIEESFGLLVKYELGLSQEEAEKVDNLRFTWQKVLAQAVEVQNLLSRVQPYFRNELIHNVAQFKKDCNKFVHDYRTQGPMVPGLAPEDASDRLIVAQNRFDTLWRKHSSYSVGEELFRLPRSEFPELGQIRKELNLLQKLYKLYNDVIDRVSSYYEIPWSEVNIEEINNELMEFQNRCRKLPKGLKEWPAFNALKKTIDDFNDMCPLLELMSNKAMKPRHWQRIAEVINKPLDVDSENFCLRNIMDSPLLQFKEDIEDICISAVKEKDIEAKLRIVTNEWASHDLTFSTFKNRGELLLRGDTTAEVITQLEDSLMVLGSLLSNRYNAPFRKQIQKWVSDLSNTNEILERWLFVQNLWVYLEAVFVGGDIAKQLPKEAKRFYVIDKSWQKIMVRAHDNPNVVACCVGDDMLKQLLPYLQDQLELCQKSLSGPRFFFVSDPALLEILGQASDSHTIQAHLMSIFDNTKTVRFHEQDYDRITAISSCEGEMVQLEKPVRAEGSVEVWLMKLLVMCQQSVHGIIRQAHHVIQDPDLNVLRFLEQFPAQVGILGLQMIWTRDSEAALTQSRADRRVMAEMNNRFLDLLNLLINQTTRDLEPVQRTKYETLITIHIHQRDIFDSLCRRNVRSVSDFDWLRQCRIYFREDMDKTNIVLTDVTFHYQNEFVGCTERLVITPLTDRCYITLAQALSMSMGACPTGPAGTGKTETTKDMGKTLGKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEFNRIELPVLSVAAQQIAVVHTCKKERRKTFTFTDGDVITMNPEFGIFLTMVSRRARCAAWPLPLSWSQRLRHCNDRDASNRGADALTVILWAYCHGIWNPRQKQFEHKHKEQIPGNYFSHAIIVQGGEVSFDPIPSSSLFFLPAYPSVAKDGNKQNLGYHGRQELPENLKIQFRNVAMMVPDRQIIIRVKLASCGFLENITLARKFFTLYKLCEEQLTKQVHYDFGLRNILSVLRTLGAAKRANAKDSESTIVMRVLRDMNLSKLVDEDEPLFMSLIDDLFPNMAQEKGYNNHLTNNIAEIVVELGLIQHAPWQLKLIQLYETQRVRHGMMTLGPSGAGKTTCIQVLMKALTKMGQPHREMRMNPKAITSAQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGEHIWLVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMSPCCKVIFEPANIDNASPATVSRNGMVYMSSSGLDWQPLLQAWLRTRPHYEQPIISDLFAKNFLSLFTWCKQNLRLCIPILQVNVITQRKLKRKVPLKRPKEQPPDPSAPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRS5</accession>
    <name>A0A3R7PRS5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative THO complex subunit 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006498</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001826">
        <property type="protein sequence ID" value="ROT74965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRS5"/>
    <dbReference type="STRING" id="6689.A0A3R7PRS5"/>
    <dbReference type="OrthoDB" id="1049195at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12680">
        <property type="entry name" value="RRM_THOC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF82">
        <property type="entry name" value="THO COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="106"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT74965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="268" mass="27605" checksum="50ED04935B940E36" modified="2019-04-10" version="1">MTAKVDMSLEDIIKANKIKPGNRRGGIRGARGGRGRGGGLRRGAAAGGGGGGGGQTRGRASGGGRPFVSNRAGFGQRGNVEGRWNHDMYQGGGGGGGGRIQQSGPAKLLISNLDFGVSDSDIHELFTEFGTIRSAAVHYDRSGRSLGTAHVSFERHADAIKALKQYNGVQLDGRPMNITMDGGASAVRNTAPVKRLAQGPRPISGASYGGRGGRGIRGSNRRGNTRGSTRGGGRGRGGMGGRGGRNQVVPTAEELDAELDAYVNQVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUZ9</accession>
    <name>A0A3R7PUZ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023443</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000696">
        <property type="protein sequence ID" value="ROT83383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUZ9"/>
    <dbReference type="OrthoDB" id="10015491at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="268"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="482" mass="53707" checksum="73B9CF492D337975" modified="2019-04-10" version="1">MFKGGGEPGPQPAAPLYPPLLRSWICAGARLEYQFQNRERISVYCAKEFDCVRSHWGRILWEISLKGETEGKVFKGGGEPSLLSTPLSSSPLVSPPLPPPTSSPSLLTPLLSFLFRYSFLPPSPTLLLFPSSSPHLLPLSLTQPHPLFYPPPITYLPLPPPLLPAPPPPPPLLPIDGVSCYNAKTVDITEIIVPQHPRSGDDVTLTCRFRLDGHGHRLYTKDESTDQSVVLKNVTEATSGEYKCEVIGEGPSFRTAVRAKQMNVIVPPQHVEILSWANPPLYRKEELVQLNCTSRGSKPRAVLTWEVNGRQVRPQDVQQFDDRTDHLGRVISVAGLRWRAPEYFQDYEAKVSCVASVGGFHTKASKEIYLDPASSAAFNHQYASAGCQLSNTWTILISWLFPFTRALLNPIRPARECYCLSERLVCGGQECCWPDTKRLLGFGAVPGTLVARTFGAHETERKIRTGQEARRRNFAEEHRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWH2</accession>
    <name>A0A3R7PWH2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1</fullName>
            <ecNumber evidence="6">2.4.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Core 1 O-glycan T-synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Core 1 beta1,3-galactosyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">C7M84_002003</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="25 26" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="22">Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01001263">
        <property type="protein sequence ID" value="ROT79281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWH2"/>
    <dbReference type="STRING" id="6689.A0A3R7PWH2"/>
    <dbReference type="OrthoDB" id="414175at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000017">
        <property type="entry name" value="Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF14">
        <property type="entry name" value="GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 25" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="17" id="KW-0464">Manganese</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8 25" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="24">
        <location>
            <begin position="89"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00040898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00041226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00042009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00043065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00059245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ROT79281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="40541" checksum="CF080EB030C5192C" modified="2019-04-10" version="1">MAHSAASIRVALLVLIASVLSAVFTFVFVVPYSPVSRRMAEPQTHEELENSADIPDNPLSLHDPHEIHHEGEAEEANRLAQKVRVLCWVMTQPASHDKKAVHVKATWGRRCNKLIFISSKNNESLGAIDVGVEEGRNMLWGKTKAAYKYAYDHHLQEYDWFLKADDDTYIIVENLRYMLSSYDPNYPIYFGSRFKPFTKQGYMSGGGGYVLSREATRKFVEEALTDEKKCKSSPHGAEDAEIGKCLDKIGVMAGDSRDSLGRGRFFPFTPGTHLMGGIPGWYKTYAYYSPYVGLDCCSDTAISFHYVNTARMYELEYMLYHVRPFGIQHKDPFPAPLPPDTASIPRPILEQAGRLEPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PY00</accession>
    <name>A0A3R7PY00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Craniofacial development protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Bucentaur</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_000634</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001098">
        <property type="protein sequence ID" value="ROT80619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PY00"/>
    <dbReference type="STRING" id="6689.A0A3R7PY00"/>
    <dbReference type="OrthoDB" id="445677at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011421">
        <property type="entry name" value="BCNT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027124">
        <property type="entry name" value="Swc5/CFDP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48407:SF1">
        <property type="entry name" value="CRANIOFACIAL DEVELOPMENT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07572">
        <property type="entry name" value="BCNT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51279">
        <property type="entry name" value="BCNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCNT-C" evidence="4">
        <location>
            <begin position="171"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="140"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00019033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00030244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="253" mass="28231" checksum="6EE0AB92F81D4286" modified="2019-04-10" version="1">MLQDEDYDSDTSDEDFVPQAHIEDKEQDTEEKEAEQDVVSSEKDKKKEDNLWADFLADVEDKPSPPPKPKASSWAALLGKKSSSSANSTSAHPVSATVKKEEPKKDLKKENQDNKPSTVKITKVFEFAGEEVRIEKEVDANSAEAKAATLTPESSTTLDKKASPVGGLGGVKRPAGLSNIIGLLDNKKQKLTTLEKTKLDWNSFKAEEGIDEELESHKKSKHGYLDKQAFLERADIRQFEIERAMRQSKRSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q0I7</accession>
    <name>A0A3R7Q0I7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003084">
        <property type="protein sequence ID" value="ROT65438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q0I7"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="618" mass="69358" checksum="E846BA5F969F8188" modified="2019-04-10" version="1">MFDGIREWAIFKTLLRRKFRGTCSSTDFFTILNECRMTTTQGPQDFFQQLEGIVYQGVRDYPDVGNPEPLLKRLFLQGLPLWLREYLAIIDELPLDRLVETAQRIWNTRTGVARTEPLADRHPPRPLRAVAPVEEPPEHRRTRWCSYHRTSRHDNTECRYRPRRLACFRCQQEGHLVKDCPFPPPSDGSAPVAGGTRWGQPLQYPRSSDTGAIGRNSLNPHLQPTSRTTDGGFKVPRSIALQSQRLDFRLGYDSRTNNSYLRLRGKAFTVRYVNKDSLELTAVVMKMKGMSVPVPPARAAIRRSVSCPPESGRFVPVRVPDALIGKQLLVEGLGYSVILPREVIKPSSKEAVVWVVNPTLNPVKLRNGTHLVELHEVEEMCDTPEAPGNVASIADTPVAAVPTSALEKISLQHLSDHPGEDAHCKLREALDVARKAAQEASRKARQEYAAYHNRNLRPPWSLEAGPRWQGPAKVVKKLGPVNYVVQDLSPPFSERNCHANQLRPFKLEEELTFPDASPYHDPDYVDPWLPDDAEPDHSNTSTSCGLSSETDVARTTNSARPYLELPECPGPPLLYLSTVRVPLDLSAQHSQQPPFDVMAASLRSAHARRPVGLAREAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q168</accession>
    <name>A0A3R7Q168_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Hyaluronan mediated motility receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003018">
        <property type="protein sequence ID" value="ROT65898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q168"/>
    <dbReference type="STRING" id="6689.A0A3R7Q168"/>
    <dbReference type="OrthoDB" id="2152335at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043325">
        <property type="term" value="F:phosphatidylinositol-3,4-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080025">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010314">
        <property type="term" value="F:phosphatidylinositol-5-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056804">
        <property type="entry name" value="Spectrin_SESTD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46607">
        <property type="entry name" value="SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46607:SF1">
        <property type="entry name" value="SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24915">
        <property type="entry name" value="Spectrin_SESTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SESTD1-like spectrin repeats region" evidence="2">
        <location>
            <begin position="393"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="707" mass="80654" checksum="BFC0B082CA27957E" modified="2019-04-10" version="1">MGSSEWEGLLERRLAVLPGSRDPGGGPILVIPLPQDPALHDVGGISATIKYLKTIPSVSSRDRGWVVVVDARVCHYRLVKPTVSTVRATLGHIRHLFVVRPEGFWDKQRVDCRKSEVDSQPIYVSVSKLTKYMELSQLPVELGGTLDYDHFAWLKTRKAYEEFVDECERARRDLETLQAELRREEPCSRASTLHDLLSVNSNTYNTITARPAIIFNMGQEVLKVLEMDEESGFRVCEGQGDAAEAASRVRTMLHDLHLLTTAVEACWRRLNTALDTYMQVRELETEMNDIGQWLVSAGQTLLADTSIGTTTEQAEAILREHEAIELKCRETYGRWAGLRYRVEDALDRGDGDLRALADHRTTTTDLRSLKDYTDTLVRTFATRLDRRRTLILASVRFHRIAAQMCERCCVLLQQNRWLPHTDDVDTLKKTLRELTARKEAIDYLASEGTRAGEKLLDLLTVGVKDLSGRDVTPDYTGELNHVHALLTNVHEQYARAARQADLHKLRLQQNIQLLTCQRDVKQAYKWLKALLEALVKAHSHVGRSSEEIRRLKTEHQQFQETATGTFEYGFESARAALLVEKSAGGSVLSESRRMVGDLEYVWKMFVQGSQEQLTRLRVAGVFFRTMEQHLERLDALYAGVMERLNGRQASDGDTRSLLSSRDRLLREIGRNVRLGKLLKERLLDPLVPNYRYVVPNRRRFSFSRCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3W2</accession>
    <name>A0A3R7Q3W2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002744">
        <property type="protein sequence ID" value="ROT67876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3W2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="598" mass="66836" checksum="0B060BF78843D56A" modified="2019-04-10" version="1">MLSIVVPPDLATYSPYRRLDFPVTYLPRLSTEHTPYTSLPSLYRMPPPVAKLRSQSLCAAANLIQPANTEGNHPYMLTRTREKQISPYSTLRHHSCLTFLSIHFLFPLKLPHLLHPPFYPNPLPYPPPTTLPPIPLLRFLPFPASYEATLPHFPLKALHRDPIAPPPKRFTSDRERPTFRPTLSSFPRYECRTTRPPLSPPPTLPTSTSAQAGGRAIALSTVSNLGLRSRSRDVKPSARVTATVARHPHPQPRTSSPGGSQHAAPPRPPLRAPAPEAMAPAHQNHPKINQRSSPTILTRNEVNVLLDQQKSSKIIDKLRNNTFTSVEKLKDTITELRLSKELKKTKERADYLDDQSRRKSLARCLRTPTRHGNTRRSRFSESCETNSISQPRLKGPIESGKKEKNKPRDIVAKFLRFQQREYIHQNRRKLANTFIYEDLCPASVDARKKQMDQLMAAREQGKLAYFSYRTLVIKEKSIKPKSTPNMTQPAPSSAATPPRPHPPPNHVSVTRPPPTASSAAPTSGSGSTETTRDHDTAHSANDLSETTWPTHTGAVPKRSTDGTHDVEETLPLEGATGPFASTDASCPSQRRVQRQKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCU3</accession>
    <name>A0A3R7QCU3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pacifastin heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001855">
        <property type="protein sequence ID" value="ROT74700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCU3"/>
    <dbReference type="OrthoDB" id="5914301at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13529">
        <property type="entry name" value="PBP2_transferrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001156">
        <property type="entry name" value="Transferrin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11485">
        <property type="entry name" value="TRANSFERRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11485:SF29">
        <property type="entry name" value="TRANSFERRIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00405">
        <property type="entry name" value="Transferrin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00422">
        <property type="entry name" value="TRANSFERRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00094">
        <property type="entry name" value="TR_FER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51408">
        <property type="entry name" value="TRANSFERRIN_LIKE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transferrin-like" evidence="1">
        <location>
            <begin position="158"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="50313" checksum="B30265383FC521D6" modified="2019-04-10" version="1">MCSMCRSKRCDKNDEYAGYTGALRCLTEGGADVAFLRTTPAPSTPRTTVCSVVTIEWCPSSPLRLMSAFGQHDPGMLTYHSVDASDSKAQKLFSALTQARLKGEENLKARKWYSSTLGIKQNLQDIFPILVNVTTREFYGKTQMNIVEAEEMCPEKPVRLCTIQADELSKCTDLQAVLKLRGVSPPLQCVMGTTLNDCLNLITRNKADIMTLTDKQRFNKQQAYNLVSLLSENYGQAKDSLYYLLAVVSKSSGINSTSDLAGKTSCQKSGNGTTADEIDAELKECLSGSSKFFESFRDAYVCLSLGHKDVAFVKYPATEPTDTDQLDIFNSDDYQLLCPNGVAPVHEDHLKECNLGRIPANVIVTRQTETGASKENMRHLMLTAAQNFGKSDSFFRLFYEYFSSKDLLFKDQTTDLSVLSDEHYQTEVLNMFSMACDLYSHHIRTSSWLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE92</accession>
    <name>A0A3R7QE92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative histone H1-III-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001705">
        <property type="protein sequence ID" value="ROT75967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE92"/>
    <dbReference type="OrthoDB" id="6372154at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000116">
        <property type="entry name" value="HMGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00930">
        <property type="entry name" value="HIGHMOBLTYIY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="H15" evidence="4">
        <location>
            <begin position="161"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="236" mass="26149" checksum="A63FA3B30F750508" modified="2019-04-10" version="1">MRTHINLPKTLASQEERGRWLAGYEKDLHNRSSITPPSQAQTSDMAPISKSKTNEQVQKEQKKRGRPKGSKNKSLAMASKSKNIGEAQKNRGRPKGSKNKSLAMASKSKNIGEAQKKRGRPKGAKNKTTDTSSKIAKPKKIGKTKAVEKRGRPRTKTDAEYPVKFVDLVLRAFKALNNRKGSSLQAVKKYLKENEGIDSQKKAIYINKSVRKLTEDGTLRHRAGIGARGTFKLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QI37</accession>
    <name>A0A3R7QI37_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001214">
        <property type="protein sequence ID" value="ROT79632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QI37"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="46561" checksum="5716789A5E59E4A6" modified="2019-04-10" version="1">MTTLPDTPLSSPPSPLLTPPPPSPVRPPRLSPPPVSPPAPSHTVTSTLQSGPYSVYPEISSTQHATDNSCTNIATTSPRSSKHNTCFDNDDSADAFAAALAKAMQEPFTFSEGKKILSKLLNQFPDILPTKDRPLGRTHIVEHSITLEPGAKPVYIPAYKNPPSRRQILEDEGRANVAADTLSRAPIETLQPLRRDDAADFPPSFSLPSSAVVNSASQVPPLEPLHKDEVYVAQRAEERYGQIIQASEAESSTVSGSHEAETGMPAVKRDQVEDRLPPRELRVNTPWTDTPCRRTRFRTLATKTDDDRSGENEDVRREPSSSADPCRSREAVRTSAQLRGGSIFSTSRARRGRWLSDMRVTNKAHHIRTPVVGTGCLYQAAISKYTPFCPTRPKGDPAGPALTISLTTLGVRTNALARPDHPDNPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QM00</accession>
    <name>A0A3R7QM00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_023489</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDLR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000700">
        <property type="protein sequence ID" value="ROT83321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QM00"/>
    <dbReference type="STRING" id="6689.A0A3R7QM00"/>
    <dbReference type="OrthoDB" id="2019384at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000024">
        <property type="entry name" value="Low-density lipoprotein RecePtor related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018696078" description="Ig-like domain-containing protein" evidence="10">
        <location>
            <begin position="24"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="11">
        <location>
            <begin position="30"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT83321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="163" mass="18031" checksum="E2B241422052380D" modified="2019-04-10" version="1" fragment="single">MASSGLTILTLFLCCAAIDVASGLEVKIEPNVMEIKNYVGDDLILSCHVKKSKEEQDKFSLSWQVPFDKNVRVNISDILGTLILSVQDLHETDRGNYTCTLMSEHDPPLRTSVNVVVLPRGRVGYCSHDSFRCLNGECISSRYKCDGHADCTDASDELQADQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QT08</accession>
    <name>A0A3R7QT08_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001571">
        <property type="protein sequence ID" value="ROT77060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QT08"/>
    <dbReference type="OrthoDB" id="6382106at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="530"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="197"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="452"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="548"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="700" mass="80832" checksum="FF7025B30D65447C" modified="2019-04-10" version="1">MPNSRERQERYQRLQQRRNVQMSSQPTSREVSPTPRRIPGGSNPDVREAVQMMVTEVTMFDQIMEKINSLVAEVWEYQEQNDARLQRHKEAFEHRMQEGTLDQEHWRNATGSWRRPAFNYAAPVPVVHTREQEIQELRRQLEERNRELTEARQRLQGSGVAPAPMECAQDREIQELRRQLQQRDQELAEVRRLAPSVQHTMTRCQDHHQQPPVINGSHSPQPLPRSRPHTPIPEQQLYPERRHTYDPQTSLPQQFRPRSSPQRPQSAHPSSQLSGTPFSYVFTKETVPHFKGDTSASQPLKKNQAIESWIRTIENIVKPATSEMFIQAARANCRGPAELIINSPLFDSITEWDTFKAALRSKFQGTYTSSDFYKVLYDMRMTPSQAPMDFFLQLEGHVYQGYRDHREAIGDPSELVKRVFLSGIPAWLQDFLSVKEDGSPTQIAETAQRIWNSRNGIRHSDTSAEENPYHPNRPPRGRDLYAMPVVAERSSPPYHRSPVRERWCEHRVRTHGTSECRARAETLDPQSPRRRCYHCRGPGHLVRDCPFRERQGDQAPGTAGRFDPRSTSRGDVTSQEGNGSDRAYRTASCGTQYLEMHHTVTVCDVRFPGDILLGMDFLRRTTFNLSSRSQDDSACLTLEGQEFHVNYTDAQSLQLSVVRVTTPEVPVNAEESRFSRVHLPLCTFTELQSFHHTMCVSWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QV65</accession>
    <name>A0A3R7QV65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001252">
        <property type="protein sequence ID" value="ROT79387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QV65"/>
    <dbReference type="OrthoDB" id="8188202at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="615" mass="63299" checksum="6ECA1A786EB02B66" modified="2019-04-10" version="1">MFGIEAKEAPASLFARSPPRLPAGRSATLGRGVGGGSDLTPAMGVPAKGSTLPRSKRHTDNPDLLTQRPPRPQTLPNPPSVPPSSHPRPRAWKTAISCWAETSGSHAFSTGLTTLRWWTTLRTLGIVEIHPPQGHLHMNGHLPPHHASNGHLANAARTTPTSAATTPARTTSGARSRAGSRPGSTTTSRRRSRTSSPAATSPTTAPRRPSTARPRPAPAPRTTRRTAAAASRSRAPSSRARARQRPRPQAQHELPEGHPQSAQKTNLQETMETSLSAGGAAPQPNGLPPHYPAAPASTRAAAAGRAAAVAALVPRRGPHPLPSPHLGRQHPHELLGRGLASRRSGSYHHLAQLRQDAPSWRPHHYSVDNLADAQVLPSDHTYSGPAVTGGAQPAGGEGGGSGGSDSGRGTAGSGGEGRAAHALDTSLDSAASQRQAGQGHSSGNDSEWVDMTDAELQRIMKKGAEGSSKAHGGGLVRRESLAATPPLPPLSPEGSPQPSPQNSPARHRKYNLSYSVGGLNKPDLLEAAGRDGGGRAGGEGRAGNSSQGSSQSTPRRGGPTQTQHSHAGNAAPSGGGGSSNHRATGGPSGAVVPKEGGGTAPHRQPRAAHQEQEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVW5</accession>
    <name>A0A3R7QVW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative myosin light chain kinase, smooth muscle-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001142">
        <property type="protein sequence ID" value="ROT80206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVW5"/>
    <dbReference type="STRING" id="6689.A0A3R7QVW5"/>
    <dbReference type="OrthoDB" id="6380783at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1820">
        <property type="entry name" value="L1 transposable element, RRM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004244">
        <property type="entry name" value="Transposase_22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11505">
        <property type="entry name" value="L1 TRANSPOSABLE ELEMENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018603231" evidence="2">
        <location>
            <begin position="18"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="44978" checksum="786403C638060F25" modified="2019-04-10" version="1">MHSYYLLLLLLFYRVSQQTSPVSLLFAEPALPLLSVALRSAPSAAPLAAPTTAPGVVLSSVQQTSPVILVIRALLHDATQSTFSHQFAVPDPRRSERSDRPTEQATGRSLGANPARDVSPEREPQLSLGRGNSKSGVRPQGNRGSQGTGGGCKELKDRLSALSRENADLKSDLAKMTERLDYQDDQGRRNNLRFSGIPEERGETWEMCQRKLSDLLRHLHITPRIERAHRVGRQTHDRPRDIVAKFASFVDREAVFKDKAKFKNAPGRVFVNEDFCAGTIKARKDQLEQLRQARSEGKNAFFSYRKLVVTERQRPRAPPDSALPMPSSGTAFDPLRLPTPLQSRPRPASLSDPPSPLMQRPSGPCFNTPPPARHSYSTVLRSPVGATALEPLPPFSPVSQRLRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIQ3</accession>
    <name>A0A3R7SIQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pigment dispersing hormone related peptide 79-penaeid shrimp (Penaeus sp.)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_019453</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arthropod PDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003564">
        <property type="protein sequence ID" value="ROT62686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SIQ3"/>
    <dbReference type="OrthoDB" id="6378554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009396">
        <property type="entry name" value="Pigment_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06324">
        <property type="entry name" value="Pigment_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0027">Amidation</keyword>
    <keyword evidence="4" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-0529">Neurotransmitter</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="129" mass="14445" checksum="1E43478265ED7A3E" modified="2019-04-10" version="1">MSQRVQVEETATKEGLERERGWTDSPYKRRQTHTRSHYIHDTDPENTFLEYHSLKDAWFYCGRLAGGGGCESSGSSGREQPQVVFELAAQILRVAQGPSAFVAGPHKRNSELINSLLGLPKVMNDAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SL66</accession>
    <name>A0A3R7SL66_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SL66"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="233"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="527" mass="57802" checksum="A816B3A3AF18A1B2" modified="2019-04-10" version="1">MCEPAVALSLYDLRTEIARRIEQTEREDGGVCPLCLGRVASGRLEGVRGADTSARTLPANRQTLTRQRRTDPRARNLEQTLDHELATAAPTSATEFNTPAAQQTNTDAEPYHRGLPDQPEHTRQPNFHASKPNSAPQQSSTNLHRRPPTELIPCSPPTTPPKNLYPARANNPQTCSPPPQPTESTAPDPPQPLKLTPAPHQPTKLPPRPPQPTKLIPAPHNPTKLNPPPQPPKQTTFYPAPQTTHQTYTPPPTTPPNSHPPRTDPPNYTPPPQPPNFHPAPTTHKTSTPPPTTPPDLHPAPTHPPNFPPPPTTPNHPCPHNHQHHPPPHNPPNFHARPHNPPNLYRAPAHTHQTYTPAPHNPQQPTTPPHNPPNLYPPPHNPPNLIPRPPQPTKLHPAPTTHPSAKTYTPPPQPTKNLYPAPTTHELPPRPPTTPNITAPHNPQTSTPPPQTPPPNIHPAPHNPPNIHPAPHNPPTHQTSPRPPQPTKLTPRPPQPPTTHPSPPYLANDVNELVRKNEQKCGRETSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLL5</accession>
    <name>A0A3R7SLL5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015969</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an essential role in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002998">
        <property type="protein sequence ID" value="ROT66038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLL5"/>
    <dbReference type="STRING" id="6689.A0A3R7SLL5"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF177">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="241" mass="27532" checksum="3158138818840F80" modified="2019-04-10" version="1">MMGGTKWVSNINLTTVLFAGPFFLIWSIQNTVAWAYHSTQALPFTTIILLLLMWIFVGYPLTIFGGILGKNGRIEYNFPCRTKNIAREIPSGPWYRSSWAHCAVGGFLPFSAISVEMYYIFSTLWGREQYTLYGILGVVFIILLSVTACVSVALTYFQLAAEDYRWWWRSIFSAGSTGGFVLMYCVFYYLKRSNMSGGLQTIEFVGWSLLTCYVFFLTLGTVSFMASLTFVKYIYRNIKMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STC2</accession>
    <name>A0A3R7STC2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative nibrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007381</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001931">
        <property type="protein sequence ID" value="ROT74140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STC2"/>
    <dbReference type="OrthoDB" id="552194at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013908">
        <property type="entry name" value="Nibrin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08599">
        <property type="entry name" value="Nbs1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01348">
        <property type="entry name" value="Nbs1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nibrin C-terminal" evidence="2">
        <location>
            <begin position="405"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="482" mass="53424" checksum="53B157ECF421701F" modified="2019-04-10" version="1">MPPPKDVDISQNNTENKENLANNQKKRPRTGSVDAMAPPTKVSNRSQVKSLPASSEPPEPTQPMESQDDSQDSEMALSRFDPKHHSTQRESPTSTAAAPSTAKKLDSRAGNSAAPTSSGQSVGPVAEPSIPFEPYTLPSLKTEAFNQEEVLTQPSHNIKEEPASCPVQEENDVILDETDYRREKRPIDEIDLTDENETHVWLGAKRTKVAEPIGTRPVKRERSPVDTSEPQARKAIKQEPEPDEELFALPGGNARIRRRALATNAPTENQVTAVSKSESTDGDENPFSLPTCSRAQRRRQQQAVVPKVEERTPESSAPAEHAQTNGIPSCVPTTSKSVITSNQGNFLSKTNSNMKQEPGQGMSNSVADLTAEVEKSLLIVEVTSLIKRRAFNNTTNLQDTTVSGMPNFKRFKKSISEVSVLPRIIGGRDLVPHDQSVSHREEWLRQQEESVCRQEDRNAINEEDEELFALPVNPWNRIRTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWJ5</accession>
    <name>A0A3R7SWJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 4 gamma 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_002586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001345">
        <property type="protein sequence ID" value="ROT78712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWJ5"/>
    <dbReference type="STRING" id="6689.A0A3R7SWJ5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="5">
        <location>
            <begin position="84"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT78712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="260" mass="29414" checksum="DC73DA149A1DF7BE" modified="2019-04-10" version="1">MKTRQKDPKREPFISHFLSLHCKQTRISSHRNLRSFTGRKQPIGKMPEGPSMTIDNGSDSPPSLRRCDNPWKRNAQHGQSEVYRRMLGILNRVTEQSLTILLEQAQELPLSDPDHLPHVLALLLDKAQDEPLFAPIYARMCRDLAARVGIQDDLTAACESHFTESYNLLLQYADILEGPISSQVIHEEILARKKFVGHLKFMSELHKVGVMSSNQVVAMAETLLEHGDDRSLEGLCRLLSFSGLALSRTNERAVYSFLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZH1</accession>
    <name>A0A3R7SZH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative dysbindin protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023819</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dysbindin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000752">
        <property type="protein sequence ID" value="ROT83008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZH1"/>
    <dbReference type="OrthoDB" id="2445127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007531">
        <property type="entry name" value="Dysbindin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16294:SF6">
        <property type="entry name" value="DYNAMIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16294">
        <property type="entry name" value="DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="246" mass="27780" checksum="4B59BC6EA062BCFD" modified="2019-04-10" version="1">MFESLKKNIQSVQDGITAGLQRLSVGEKSATTPTESNVNLAAGEDLLQMYQTQWATMHHMAEQNAKLAQDIDSAITTLTHECENQHGQMAEIHSLLAHLPNIMAQLHSMLATIGSLRGLFEEVEGGLLALEDLEEDLALQEKTLDLRLSLALSREKHNHRLNALRNELSVTHQAKMVALEQHQETQRKEREQVFSEQFTEDLKNYKERGVVTRRISSSEDEQGLKLEEVDLEQDTSELDQFLNDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAG4</accession>
    <name>A0A423SAG4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_021045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004292">
        <property type="protein sequence ID" value="ROT61212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAG4"/>
    <dbReference type="STRING" id="6689.A0A423SAG4"/>
    <dbReference type="OrthoDB" id="10062378at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005918">
        <property type="term" value="C:septate junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035151">
        <property type="term" value="P:regulation of tube size, open tracheal system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019991">
        <property type="term" value="P:septate junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004031">
        <property type="entry name" value="PMP22/EMP/MP20/Claudin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284">
        <property type="entry name" value="EG:80H7.2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21284:SF11">
        <property type="entry name" value="KUNE-KUNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13903">
        <property type="entry name" value="Claudin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="222" mass="25797" checksum="08F7D18EFB1E26AF" modified="2019-05-08" version="1">MSQLSEYETFEPTTHPWGVTISLISFLAIVISFCSPYWLKNDGELSEGHFLNTGLWEACFSNYHDYTYRYDRIYDGCYWTLDEETHVIAEQLRRPFFVTVQVFYTFCFTLSLLGAGLTGVLILCPGEDFEKYVLKLAYIDLFISWFFGFIAVIVFGAMGDNRDWMPHWDHNHLSWSFGLAVVGVVAEFVAAVLFWVEYRIQKRKESYRQSHGVFTLEGGTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SD43</accession>
    <name>A0A423SD43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative facilitated trehalose transporter Tret1-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_020079</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003834">
        <property type="protein sequence ID" value="ROT62090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SD43"/>
    <dbReference type="STRING" id="6689.A0A423SD43"/>
    <dbReference type="OrthoDB" id="6355042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="584"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT62090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="70554" checksum="2540E09B1018DE46" modified="2019-05-08" version="1">MQFSWNAVLPKLEDTSKFIVTKEDVAWLGSLTFILIALLSPLAGILAEHIGPRRLLVTAMFPVAGVWLLKAYGPCLWLLYLGRALLGVSATVVYTVLHPLIAELCPARIRGLALVLPEIFGCVGMLLSYLLAYFLSWEAATAVSAAPFVPLSFMLLLVPESPYWLVRKKKIDAAEKSLRFLWGRDANVDRELEAIRSTTISEQNKVKNQIKKLRKRHNAIPVVLTISLLILKELGGRGPTFTYSVYMIRYSGVQLDAFYCTIFIGVARLASTCVSACISDVVGRRPLLVASTLVCAVSEGVAGTFLTLEAEGPTWVPLASVIVFAIGYGLGLGPISWVYIGELLPTPVRYLGSAMAIFGGFLTYFVLNLVFLNMTSSPGLEFTLLLFGGANLTIALLVLFFIPETAGRTLHDMDKAFVSNRRQQGRHNSTFEIDIIPSVADRARKFEDSLFNMMLTRHQSVRSVRQSARSVRQSVLLSVSVRHVSKVSRCASSVSQSARSVCPCVSLPVCSPFCASVCPFCASVCPFCVNQSVRQSARSVWRQNQSARSVQGLVLPLVISGSQPELRMASAALAADVTMHKETLQQLKEGHEQMGQRMQELERQFVEVERRMEEQNQQMVEERRQSAERHEQLLKMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDK5</accession>
    <name>A0A423SDK5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_019877</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003737">
        <property type="protein sequence ID" value="ROT62285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDK5"/>
    <dbReference type="OrthoDB" id="6352760at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="284"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="90"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="398"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="563"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="629"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT62285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="783" mass="85265" checksum="A1A6154AA18309F8" modified="2019-05-08" version="1">MGQLGSSVEGVKQLLPLVMQTREDIDRKVSTRLACGAVCMSVGCQAYTLRDHLCTALSDVYELSYSAADQSLRVYASEELLLTTSSTSTTTTTTITTSTSPAPTTTSTSSTTSAATTTTSSTSAAPTTSSCTSLLLLPHQAHLLLLPQQHICCSYTTSTSAAPSTSGYICCSYTSTSAAPILLPQQVHLLLYHITLLLLPHQVHLCSYQQHLLLTTSQSAAPTTSSTSAAPTTSSSCSYHIKYLCCTTSSTSAAPTTSSTSAAPTTSSTSAAPTTSTTTAPAGCLTSYIANAEYVLKGPSGSIVADNSTFYVDGQDCSWRIIVDEGFLVSITWLSFSVEPSYDYVSVADPCLGSDGYAWQTYDGNSLPPDVVSTNNQMRPQKLQIVAPIRSRSETRPFVPRAQRPLSRPRLPSQAPLTSWEQTQPLGRQTNTRSPASFPPRFSFLSFSSRPMLYFLLPCLLPLSQFHDRSIAFSAYHFIYLIFSIYSPHLFASSWLQSLSIPPLLFLFFHLPPCPSPRKTLIKASLSLHLSYFFLLSSLSFPSSPLSFFFSISPSFLILRSPSHRHSPHQTQKQRTNKNYNLSTPSKGGQRHLNRPKHGEVFIFGSNFPLSPPKNAPPSAASLMKHPGRGVPSVPRPGSRTAPSKRASPLSSPSSFLQAIIFHFFSSNSFIPSLRTFPSSFSASSIFLFPSFLFLHRHFHSTTLPLFFRLLSLPFLFQSPYPFPSSLPLILFQSPSLFPSSLPPLPFSISLSLSVFSPSFSSFLSLLLPFLLHPLFYTPSKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEE5</accession>
    <name>A0A423SEE5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003621">
        <property type="protein sequence ID" value="ROT62578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEE5"/>
    <dbReference type="OrthoDB" id="6379939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301:SF12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21301">
        <property type="entry name" value="REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="57232" checksum="235590B43E67C4D1" modified="2019-05-08" version="1">MENIVARQDEQLTARSQGTATSPAKWNKSATSVFLAGFSGSCLTGKKEKEKEAKEKAEKTTNTRRHKGTRECPTTKRSHKSAPEEKVQDTGNDGGTEAGPEEEHLEPTPTSPTKECQGKQGKRYPTNTPSGLPEKTLPPPRFPKERVVPQPSEEHIQVAGTEEPHKERRHNMGNRYNGWADHQRGNSQWGTGRREGRQWQEEDPNNWAWNGGQRDALLEHKPSIPHWYVLPKTHKPLDHVTGAWPGRPVLSGCSSPTRPVDRLLTTYLTPLLDLLPERLQDTTSFLQKMRDAKRYPGAILFSFDIVSLYPSIPQEEAAYVVANFYEQNFSYVEERLFSDFNMAAPPPYLIKEGIDHVLGGTLLRFNNRFFRQGKGTAIGASVSVAALRIKRIVSEEHKLETALQEMTGFFKARGYDNRCLNSALERVGNLQRDQLLIRKGHTLGNSLQDPPTNDSMEERKIDCREADQSAVPVASGRAQGVNEWQTTKLRYLKENRGGPRLPQSSKPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI64</accession>
    <name>A0A423SI64_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003364">
        <property type="protein sequence ID" value="ROT63849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI64"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="56686" checksum="381FCF01B8DAEA46" modified="2019-05-08" version="1">MSVPLLTSPSPHRSTPSSPLSLTTTPSPLPAPPSLTLPLVLSPSPLPFPSLSPNSPLSPTLLPLPHPLPSPLTHSSPPLPSPSLSLPPLPLLLSSSPLPLSSPSHPLSFSSHSSPPSLTLSPPSLPLSFLLPTPFLFPSPPSSLSSPLFLLLPLSFLSSSLLPSPSSPPPPPLSFLSSPPPSSPLSFSPLSSSPLLPLSSSLLPTLLPLLLLLHSPSLSSSSSSSHSFLLPLSTPPPPSASLSFPFPLLFPSSLLLSLFLLPSSPISLPLPLYSLPSPSLYFPLITLYYLSPSILHSPSPSTLLHSRLLSLTSVSSLVCLLSLSLSLFVCSSLSPLSSVSSLVSLSRLLLVGLLSRRSLSLVCSPSRRLSPLCLSPLSSVSLSSVSSLVCLSLSPLSRLPPLSSASSLVCLSRLLLSRLLLSRGAPLSERACYAAEGRDAQRSGVPRALSHLHVLGRLGLSPPPYYLPLPLPLDRSSAPAPLPRTKDLLRSPPSPYAPILHSVLSLSSPPSWGNLVHIVRVRTAGKGRTHQCGNKNTKGICY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLF0</accession>
    <name>A0A423SLF0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="7">PARP</shortName>
            <ecNumber evidence="7">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_016966</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01003147">
        <property type="protein sequence ID" value="ROT65075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLF0"/>
    <dbReference type="STRING" id="6689.A0A423SLF0"/>
    <dbReference type="OrthoDB" id="429950at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990404">
        <property type="term" value="F:NAD+-protein mono-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070212">
        <property type="term" value="P:protein poly-ADP-ribosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01437">
        <property type="entry name" value="parp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.142.10">
        <property type="entry name" value="Poly(ADP-ribose) polymerase, regulatory domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050800">
        <property type="entry name" value="ARTD/PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004102">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036616">
        <property type="entry name" value="Poly(ADP-ribose)pol_reg_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036930">
        <property type="entry name" value="WGR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008893">
        <property type="entry name" value="WGR_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10459:SF66">
        <property type="entry name" value="PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02877">
        <property type="entry name" value="PARP_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05406">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00773">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47587">
        <property type="entry name" value="Domain of poly(ADP-ribose) polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142921">
        <property type="entry name" value="WGR domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51060">
        <property type="entry name" value="PARP_ALPHA_HD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51977">
        <property type="entry name" value="WGR"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WGR" evidence="11">
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            <begin position="335"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="PARP alpha-helical" evidence="10">
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            <begin position="499"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="9">
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            <begin position="673"/>
            <end position="888"/>
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    <feature type="domain" description="PARP alpha-helical" evidence="10">
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            <begin position="866"/>
            <end position="983"/>
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            <end position="1220"/>
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            <begin position="833"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
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            <begin position="472"/>
            <end position="483"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
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            <begin position="840"/>
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            <dbReference type="ARBA" id="ARBA00004123"/>
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    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00022676"/>
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    <evidence type="ECO:0000256" key="3">
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            <dbReference type="ARBA" id="ARBA00022679"/>
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            <dbReference type="ARBA" id="ARBA00022695"/>
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            <dbReference type="ARBA" id="ARBA00023027"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="9">
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            <dbReference type="PROSITE" id="PS51059"/>
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    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
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    </evidence>
    <sequence length="1220" mass="137301" checksum="C48518B0856AAF73" modified="2019-05-08" version="1">MPNLSSMHTCHSTSPILMQRIHPNREGSDDVMNPILLDGTVPECKQGHRSIASFAMNLVAWFVDNHEHYPGLLNPLSHRFLLPFTLASSHNHPPSSLLHPLFSIIPPSLILPSSSVIASPPFSFHHLLISHHPSFPLRYRLPDPAPFPPPSWSRIHRLSSVFLSPPSFPFFIAFLRFLSPPTSLLPPSPPSSALHHLFIILRCSPPLFPVFTASPLPLLHRLSPPFFTASPLPLLYRLSPPPARPRQAGARGQREHAAAAGDLRGPGGRPEEGRQAQAGRLPQLHASRLSVSCPLFLSPFPFSFPLSSIHSLSFPLFPFLFSLPYVSFQCIFPFQATVHEEYACMLNQTNIGQNNNKFYVIRSQRQERLPLFHQWGRVATVHEEYACMLKPDQHRPEQQQVLRHPGRQRQRGFSLLHQMGESGRGGPVEHRLHGEGEDAIKAFEKKFKDKTRNNWADRDNFEPVAKKYTLLEMDDDSDEEEVGGDSSEPKKELVSYDGPCNLHKRTILMIKLIFSDDMFVRQMADMSLDVKKMPLGKLSKLQIAKGLEALIDIEDAIKKNKPRSVLMELTSKFYTLIPHNFGRSAPPVIDTDEVVQKKKEVMLTLSDIELTQSLQKEKIISEYATACPYSRKGPLLDVWRVDRKGEKDSNRVSRNFFSSPPILPPPPYTSPSIPLIPPPPLLYLSLPLFPFLPVPLALPRPSFYLYPLSPSSSPTPKPKNNKAKAKPARFAAHDAIQHRKLLWHGTNVAVVAAILKAGLRIMPHSGGRVGRGIYFASEHAKSSYYVGYHYGTYEGESNVGFMFLVEVALGKENNIMQDDCSLTQAPKGYESVVARGKTEPDDESDEEEDEVDSSTPKKELVSYDGPCNLHKRTMLMIKLIFSEDMFVNQMADMSLDVKKMPLGKLSKLQIAKGLEALIDIEDAIKKSKPRNVLMELTSKFFTLIPHNFGRSAPPVIDTDEVVQKKKEVMLTLSDIELTQSLQKEKENKDLHPLLEKYEMLDCLLEYVEKSSSEFKVKLLKEYATACPETRKGPLLDVWRVDRKGEKERFAAHDAIQHRKLLWHGTNVAVVAAILKAGLRIMPHSGGLVGRGIYFASEHAKSSWYVGDHYGIFEGERNVGFMFLVEVALGRESSITQCKCSLTKAPNGYDSVVARGSCEPDPKKNKKVVFDGKDVIVPVGKPVPQKEWAQSGFCQSEYLVYKESQARIRYVLKFSFEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNU7</accession>
    <name>A0A423SNU7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative titin isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016131</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
            <location evidence="1">Sarcomere</location>
            <location evidence="1">A band</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003018">
        <property type="protein sequence ID" value="ROT65896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SNU7"/>
    <dbReference type="OrthoDB" id="6375732at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031672">
        <property type="term" value="C:A band"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040017">
        <property type="term" value="P:positive regulation of locomotion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060298">
        <property type="term" value="P:positive regulation of sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045989">
        <property type="term" value="P:positive regulation of striated muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Muscle M-line assembly protein unc-89"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Myosin light chain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Myosin light chain kinase, smooth muscle"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="9"/>
    </dbReference>
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        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
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        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
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        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
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        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
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        <property type="entry name" value="Spectrin_met"/>
    </dbReference>
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        <property type="entry name" value="Spectrin_repeat"/>
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        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
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        <property type="match status" value="9"/>
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        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1033"/>
            <end position="1122"/>
        </location>
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    <feature type="domain" description="Ig-like" evidence="10">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3308"/>
            <end position="3346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="3355"/>
            <end position="3364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="3373"/>
            <end position="3391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3491" mass="389493" checksum="31DDA86C57D27109" modified="2019-05-08" version="1">MDAAERVYTDNVLPSDAEGARQLLSQLHDHKRAILEASMYTLQEAQALLARLRGLATEGATLDSRPQHIKTNIEFACSQIEHYLESLHDRRRFLDGLFSARKHHLEQCLALCLLYQDLTEAVTSLKQLRDEVSEHQGLGESQGNAEILLHEHLRRETAAKEQQDKCIRLLKTAERMASGGHYAGLEARSRAYSVLEAATALHETCDTRTALLQQSILFFKLAQTAMTKLDQAEVQVASLGGEGAQRLSLVVGVVEEAIQPALAEGYAILEVTGGRNQPHNLGISLVVEELERRRSHLSSICVSSTEQVLQRTELSNAFLEQYNSIESWLVRIGDAFLQGHQDPGGSLSLARDFLHLHQTLNNDVMEKKREIDSLDTFLSKLLRDLSEEEAAGYQEKMQALKDHWDALKKVLDIRIAISDKYVKFHEDAEAVNNEHESLEQLLKEAHGEDIVPQVEAKWEQVQKLYLDLCNNGKAFCQDVKNVEDPYLDTNRAVLCVENILEQLGKRRLVITDLHSHFHMKITTTKEMLLLWNTYRENVVKMQSEMSSLETDFCPLLRGDPADPEDIANTLDQRLSVYVSAVKKTQEDIQNMMTRAEVMSYKGDQGGQRDEVIGALLQLYQNLQNKATEYQILGHMLIQWCRNIAEIHRSCDKLESQFGNVSLDIGGIEGQLLEHEASKQAVLELLKFAQNESTSIVTKIKEQCPPDAGAKDIGMINEMLERRGRVFETVISDQLRDLSEQLGRMRGHYGDSLAAAKNMQTAFTQFKITVDMLERRIQTFVSTAVKMLGQEDDSGEVQQELAELEKKWSTFQRQVGESEKSIELSIDFFKLVEEAEDWFKNGSKLLVTVAGESSNIQNPDQAQKLRKRIEHFLQPGEQAQAERITKISSLALQLYGSATPRQIEVVSHQNTHMLESFNVINRNLEMLIINLKNAEDLREKQKKEKEELAASLTAAQAEAEAARLRAAAAEEARRAAEEVARTMAIPVEPIVPEKVEIEIQTEAIPLPPEEPRKPEETPPAKKAKLIDDEPQHMPPVFMTPLVGASVSEGVKFSFECRVIGFPMPEVEWLKDNMSISGNPDYKTSFEEGICTLTIEETFTEDSALFTCKAVNAAGMAETSATLTVKEAEAVEVMAPPLFTKRLIDSAAEEGSSYQLEATVEGHPLPVVSWSKDGKCVDESPDYVITFNNGECVLRFEEVFVEDQAEYQCRASNDLAVELSERPKFTMLLSNVMARAGQKFKLECQVTGNPTPTITWFHNNKPVKETPDCRLTFDGQTATLVMSEAFPKNAGTYTVVAKNSAGEAQCSANVSVKGRIPTETSDSEVASDIDAEPVKPSVQLPLKDTSIQEGRPARLDCVIVGQPEPEVIWYHDDKPVKESNDFKLLFHGDRCSLIIQEAFLEDAGIYRVVAMNSAAVPELAPPSEPEAPTVAPRFSQLLTDSHVTEGKPITLRASVTGEPAPTIAWFKDGVPLLPDNEFQIQENRDGSLIVHINAATLDHTGQYEIVASNAAGTAKCVAYLSIEPRLPTPPPPEHREPPVFTKLIQDVTVTSGSGVIFEAEVTGVPKPTVYWTLNDCHLTGQEYLHGQLQYLIGNRGSVHSLELPTTSKLQAGIITIVAENAAGKAVSAAALKILDPPTVVAKPAAMEPQGKPQHHVREESYTSSTTSSSTMFQQTSRMETSHITKVVMSSGGSMDEKKHSMSAASTSQVKKVSGQPATEVHKAHFQEVKQDGIAPAVVSDKVSMVKIEGDKVVQQVSQDSGTVSITPPPKKFATGKRKAAPARFITPLQSIIAKEDDRIVLESTIDGYPDPSVTWTHNDGPLKDDIQVKTQLNKTSLTIPRVNQGHSGHYTCFIQNEGGSAQCTCDVIIKKKQFPPVISKRLQPVVVGVNERLHMEIDVTGTPLPEVSWTKDGQALTASDRLTQRSEGTRHLLIIQEAQLDDSGRYGAIATNPAGRAETLADVMVTQLIIDETSQTHKIVFTDVTDETKMFTSRSEEVHEERRGGAPGTKPTPETKPTKEEKKPKYEEFRRETHGHPGKSGPYSEDTYYAMKDESDISTEGRRTKKKVEMKSETHVEVMSDKKVEVFESTSVDVTPKPKKKQVVKMEQKHEVKAIQDARPAETSAPVPTSEPKVKSTPVAETKTSEKEIKISSVTECKEHLVKESFTSEKQDLPQQVIKPVKKVSLKTEPEKDVKAPLKVPKIEPLKSTGLVKQAVTIQEKEKIELDLKPFPFEPDPEKPKKPRGQPPSHPSKFKKGEFHESDYDSDYEGKIAPKWKPADSDAEENVYGKVQPPLGKSKVSQPHVRTPTPPSAFDQPPQFEGPARPKIDFPESETEPERDVSPEIVIPEKVEYVAPPEPPKVAPKEPKLFRSQPPKKEFPKKEPPKREPPPRSPSPVLQPGTPPEELYAESKPKESPFSNAIGVESTKITKIADSSAYHKRFVTMQQTTRVIKFTDSRTATTSTESQQASSSERKSRSTKREEPKREPLPALEPFPFTPDPPKPKKDRGAPPPKPKKFQKGEFTGSDYESDYESRIRPKWQPPDSDAEEPNYTKVKPQLRSDRTPSKTRERTPTPPTVFDVPPEEGPWRPSVEKVEITAEIVPSPEILIPKDVPKKEIQRKVVVKATKSTEKLPERPVSPELPPPGTPPEEGVIIQQTEYVVDKVDVKSRILPPPMQEVQTYEEKPYTKIIERTEKTFTDIKLEEEMRMKKEKMERKITTETDYEQVPERPPPPVEEEQVVVETERLMDLEPFPFTVEEPKPKKERGPPPPKPKKFYKGEFRESDYESDYEGRLKPKWKPADSDVEDPEYTPVRPPPPRERTISKSRERTPTPPSKFDVPPTLGEPLRPVIKPVDQPLVQAFKETSPEIIIPKIEEKKVSKTPKVVPKAPSIKVKQEEPEKPKVPSPPLPEPGPQPEIGYVEGGTATLVQEEEDAHIRMIKKKIEAKKGFQIDIDITDIYDFVSESELEKTDTESGKGKQFPKLEPFPYEPEPHRPKRERGPPPPQPKKFFKGEFRGSDYESDYDSRPIAPKWLPPDSEGEEPMYRRVAPPAGDPGKRRSESSGRDPSPPSKFDQPPQFEGPPRPVVELSDIPRRERRESLEEYSIPRFPKVEFKPFDLEDENRHHPHISHTTDTETEPEAFTQPLSPTKTGIDKKYAKSAQKVVSHQFEDMTQTFRHKAQKFAEQLVTEVFAAREGSVPAEPAGEPPSMPEELKKQSVSPVSTAAPPTTADGLATDVQEPQAYRDESRVSEFGTKHIDPDTGLIYFKYDFGYEFGVILPGEAKKLEKKKEVNGDRTTDIPIPVIHEKSGTSCKSEISSTKTNGHIQTPQEKSLQEEPPQTTGKTLSTEAPEEDHTSPQPSLQSDISETDPPGSPLSATPPSTPSTPRSGPLTQPKRPPHYITPLRDLAVLVGETLRLECVVQADPPVQVTWSKGGSVLQNGPDYQIVYRNGVCRLIIPQVLPEDEGVYTCTAVNLLGVDSTSGTVCITGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPP1</accession>
    <name>A0A423SPP1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPP1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="20083" checksum="10AB6255544C3D2F" modified="2019-05-08" version="1">MNQFLPLVGQESKKVEDGCAAPASRLDFTDPSVQKQTSQIQFLLDRVYIIEDDWEKLQETLSKISKQMRGTIRDSETNLQIAIEKARRLMDSVGTNHRLTNEAHASTEMILDCGFFLKKNLADDNPSSEQGSRSVMSNNNGFADQSTNSCEKSDSTYSTSHQSSDQLESFPSYDGISNGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQ18</accession>
    <name>A0A423SQ18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002960">
        <property type="protein sequence ID" value="ROT66316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQ18"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="11999" checksum="7C7E20007C1B43E8" modified="2019-05-08" version="1">MEQLNKEKPVDVPCGMPNSLGNSPRGLHTSLEGGLDDIDLLSICKVTPIDQLVDKVVGKTTNPELELTPLVSPKKRRPPSVGDDDKENFAQPRVPTPGHKSRKKATPSTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQR6</accession>
    <name>A0A423SQR6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_015365</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQR6"/>
    <dbReference type="STRING" id="6689.A0A423SQR6"/>
    <dbReference type="OrthoDB" id="6373057at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="5" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT66566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="20077" checksum="89D2FB3236CBAA9B" modified="2019-05-08" version="1">MLACGTDYLTETELSRSYLYIYSVWVYLFPLAYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFVAWTPYFIINWGGMFNRPMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACNTEGRDGGASDAGSTATAQSTEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQX8</accession>
    <name>A0A423SQX8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative metallophosphoesterase MPPED2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0046 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002914">
        <property type="protein sequence ID" value="ROT66635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQX8"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07379">
        <property type="entry name" value="MPP_239FB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024201">
        <property type="entry name" value="Calcineurin-like_Pesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051693">
        <property type="entry name" value="UPF0046_metallophosphoest"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905:SF0">
        <property type="entry name" value="CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12905">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035808">
        <property type="entry name" value="Pdiesterase_Brain_239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="298" mass="32980" checksum="ACD5D20281E22D14" modified="2019-05-08" version="1">MSGGKVTVHPITNNPTQAWEQIRTTQRTIKLNVKTPTTPPDENMLRFVCMSDTHSLTSHIQLDIPDGDVFIHAGDFTRCGSAVEVEEFNNWIGALPHKHKVVIAGNHELSFDSKFTTTTRQHHKTAHTGDSLINEIPDLGMEREELCAAVAEQNTVDLVTNAIYLQDQALTICGIRLYGTPWQPEYCNWAFNLPRGTSCLEKWDAIPEDTDILITHTPPVGHGDLCCTGVRAGCVDLLSTVQTRVKPKYHVFGHIHEGYGVTTDGKIIFINASTCNINFVPINPPIVFDVPIPSGFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUT0</accession>
    <name>A0A423SUT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002736">
        <property type="protein sequence ID" value="ROT67959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUT0"/>
    <dbReference type="OrthoDB" id="6334967at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="16805" checksum="37FF4CFEEB9B0300" modified="2019-05-08" version="1">MWSFSSSWRAEEELQDDLEQLFDDPHYLVEANKLRAYFSYLKLENEKCRQKFLCELATDPEAFFPASDIFLKELQPSHGPVKEDAKNRFWLYQEASRAGLMGGRGECVRLFPACRTPITDIINTSVLKVWQFIGRKLNISFTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYN5</accession>
    <name>A0A423SYN5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Actin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012617</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SYN5"/>
    <dbReference type="STRING" id="6689.A0A423SYN5"/>
    <dbReference type="OrthoDB" id="6330430at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41812" checksum="0DAAF854F44CA610" modified="2019-05-08" version="1">MCDDEDATALVVDNGSGMVKAGFAGDDAPRAVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWYHTFYNELRVAPEECPTLLTEAPLNPKANREKMTQIMFESFTVPATYITIQAVLSLYASGRTTGEVCDSGDGVTHFVPVYEGFALPHAILRLDLAGRDLTHYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFESELNVAAASSSLDKSYELPDGQVITIGNERFRAPEALFQPSFLGMESAGIQETVYSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILSSLSTFQSMWITKDEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZ86</accession>
    <name>A0A423SZ86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Synaptic vesicle membrane protein VAT-1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002545">
        <property type="protein sequence ID" value="ROT69606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZ86"/>
    <dbReference type="STRING" id="6689.A0A423SZ86"/>
    <dbReference type="OrthoDB" id="203908at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052100">
        <property type="entry name" value="SV-ATPase_mito-regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44054:SF1">
        <property type="entry name" value="SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44054">
        <property type="entry name" value="SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="18198" checksum="11B2408FE3A169A0" modified="2019-05-08" version="1">MQENGVDYAIHHGQDYEREILKVRPQGVSIVLDSLAGAEFTRSQNLLEPLGKVVLIGAKGMIEGEHRSLWCILKTWWNTKNVSPQSLIMKNHAVAGFHLTELRKRDPKAFRKGWMEVRDMIADGVLRPRIDSVWKFEEIVEASKQISERKNIGKVIIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0E0</accession>
    <name>A0A423T0E0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002496">
        <property type="protein sequence ID" value="ROT69949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0E0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="53365" checksum="B6ECD46301FA0126" modified="2019-05-08" version="1">MSSAPSSSSLHPPSCPPPPPSSSFPPSPPLTPSLPTLSFLPPAPGFLKSPPSPTPTPTATPTPITPSLLPSPSHSPHPITPHSSPPPTPHSPPINPPFLPSPARPPITPLAEMGQGERAPTGRRNAQEATWSLPPRRKLSKVEDSGLTFQVDRRAITPRSPEGRCLLNSTIQAARGYTGFLPPRRLSVENPPSPQFYRRSAFKNSRSAGSVTGLPLPFGHLPLCSNPRDSRKRKPQVTGRYVCLLKFHFQLGSQVLFRETLPQVEARVNLSLTTQREHQVNTKGCALLIPTVFRLGSQSASLRENPQVEDLVRLTSLNPIHPRQLRSPRQSNTPTEDARRSPLNAGPPPQPKRPPPPPPTRQVTRCRGALPFLKNPQLVGSGQLRVQTKKNRVLLVSLFFLPLFPLCPLALSPYSPLPCCFFSPEREDSFLFVLRFNSLTSQNRFQSIQNLTLILAESTTQGPQTDPRPSIMTFTTSFSFVSSTTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2E7</accession>
    <name>A0A423T2E7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_011110</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002408">
        <property type="protein sequence ID" value="ROT70591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2E7"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17358">
        <property type="entry name" value="MFS_GLUT6_8_Class3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000055">
        <property type="entry name" value="Facilitated trehalose transporter Tret1-2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044775">
        <property type="entry name" value="MFS_ERD6/Tret1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="25"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="476"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT70591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="486" mass="51981" checksum="AA18D0D806869D04" modified="2019-05-08" version="1">MAEQGMSSADLVNNARPARATQYIAALSATMGALCFGTALGYSSPAGILLTSNSTDSSLQLTTVENSWFSSSVNLGALVGGPIGGLCINAIGRRGTMLAVFPFFFGSWAIIAFAQNFAMLLVGRIIAGLCTGMVCIATPTFIGEFASADIRGTLGAGFQLMAGVGILYAYIFGAFINSWQILAVVCAVPTIIFCVLMFFSKESPSYLLSKGKEKEAQESMRYFRGPDYNIQPEMQILKQTLEDSKANKASFSDLKQAYILKPLLISIALMLFQQLCGVNAVLFNLKAIFAESGTDLSDDVSSIIVGVVQVLATVVSSVLMDKAGRKFLLISSAGAMTVALVGLGVFFYLKENGDVSALGWLPITSLMIFIAAFSFGFGPIPWLMMSELFPANIRESASGLSTMTNWAMSFIVTYFFESIRDAIHEYGVYWLFGGICAVSLVFCVLVVPETKGKTLQEITALFGGPATSPKAARPSAPSTGSEKMRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5C7</accession>
    <name>A0A423T5C7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Vitellogenin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_009952</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDLR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002259">
        <property type="protein sequence ID" value="ROT71709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A423T5C7"/>
    <dbReference type="STRING" id="6689.A0A423T5C7"/>
    <dbReference type="OrthoDB" id="6345916at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042562">
        <property type="term" value="F:hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000009">
        <property type="entry name" value="Low-density lipoprotein receptor isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000024">
        <property type="entry name" value="Low-density lipoprotein RecePtor related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14670">
        <property type="entry name" value="FXa_inhibition"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 12" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 18" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1023"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="14">
        <location>
            <begin position="95"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="LDL-receptor class B" evidence="14">
        <location>
            <begin position="843"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="17">
        <location>
            <begin position="971"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1168"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1268"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1279"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="337"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="375"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="488"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="536"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="998"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT71709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1331" mass="146759" checksum="51551200171A0DCA" modified="2019-05-08" version="1">MIDWLRRNVYWIDGTKAAVEVIREDGAFRTELLKAMPHLTSITLAPLLGFMYVSDASIEPFIMRCGLDAKSCSKIVTVDLVQPLSITFETNPDIKRLYWCDRALGRIESVAEDGTDRRVFVQNAKSPVSVLVTRSQILWSEERTSLIYAASKLDNSSVRAMALEMGIPENGERSLKLMEVGWKVPEQLAATNHPCLQSNESCSQLCLGDNFSEKVCACSFGYKLQVDLRTCESVKCNDIQFHCFRSHTCIPSSWKCDLTPDCQDGEDEEDCNQPQACKEKEFQCSTGSCINKLWTCDGVHDCEDGSDEKLDECSNVTCSSVHWRCKSGMCIPKMWVCDQEKECDDGSDETECDTSCPEHKVACRDGKCVPKVWKCDGDKDCLDGSDEENCPTECKSNEFTCGNKNCVPLRATCDGEDDCGDGSDEGLPSCQPPAPPPTCHKGQIMCERHDLSSPPICIPLVSVCNGVRDCPLGEDEDCDYCARHEFSCSSHGCIPRGWMCDGEKDCTDGSDESPYAGCPPGNDTVSDVCGTHEFECGSGGCIASRLVCDGLVDCLDGSDEGSLCAKTCLGNGGCQHVCKEGPKNRICSCWKGFKLAEDQTSCVDVKECDDEATCSQKCEERHGYHLCSCLPGYTLRQDQRSCKPIGGDEYVVAVHPGSILNMSHSFHLVEKVTMPSHVQFSSLEFAPESHHFVYADKAHGTIGKMSMDGKLTTLLKHRKRPQGLSLDPISNSVYFSEEFGKAEVVDNGLPRARRETSADGAYSVIMVCGMEGDRECSMVYQGHGEEIPAIRVAPISRRLFFCTNNMAQEEAKIFTSDMDGRSARIISHKVVKCGDLAVDEAKERVYWTDLSRNVVESVKWSGDGHRIIKENVHTPIGLALSGDWVLWLDTHKHQVIKCNKFDVGVCEQHTMGSAGIALIVQHRLRMESSMIGACTAKNCSHHCTIQMDKKANCMCKVGYTTAPNRPNECVRLKSCDHSPCRGEGICESHSDTEFICRCPVDHEGALCEVAKTPTADNSDSSSATLGVCLFLIIFGALIFGLYWYRKRPFPFWKGKGGQLRKRCFKANQTLRFANPGFGIISPTTVPNGNTASGINTIPSTPPVLRGSHNFENPFFKTDEHVPDTSADSAIVSTADSTSINIAPHQVDLTTPQHVLKPPVEKKVEWDLSPFQPLQPPPRSEYKRRWTQTEEGGCSQDDPRGEGRANSCRYLQGKPREQVPEEPFLNPRPQWRDLNGKACQQGHASRAMPVGPAGPAPAGQCTCRTPITKQGHARRATPAGSRQQGHTKTGGQRKALPPHPNWTKVQQQCARLFCPEINGTGWDLHFGKQFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6E5</accession>
    <name>A0A423T6E5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT71993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6E5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="40795" checksum="C628D9894BEAF72F" modified="2019-05-08" version="1">MKKGNEIALDDITIRGVGTGDGEAGSDDQQEYDVESSGTSPDEAGRNETVANSTAVGNETSGAGDETDQGTAEPETNTEVPQNATEEVEGSVTEAPVVTGDSEVESNATDIPIDLPGITEGEGLNQGTENSSLVTVSVDNISSAPGNDSITDNATESALNETATVTPAPDSVENNTEEASQDPLAVNATVEVPENENMTLSITDFPVNATELPETNATITSNGTEFVNETFSPVNATVEPSVDPQFTPGVEGNGSVFSSTPVTSFITEFPPPHGPPTDIITDPYSPINTTVMTNFTTPSGSASTGDAAILAGDDITSSSWGMFKIFLVICVLGVAALGFLYWRKRRQQDDEIPVFTRSSHADYHNPTFSPDDDSSFASQGTRHNYKSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6T9</accession>
    <name>A0A423T6T9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dual specificity tyrosine-phosphorylation-regulated kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009401</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002191">
        <property type="protein sequence ID" value="ROT72226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6T9"/>
    <dbReference type="STRING" id="6689.A0A423T6T9"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF22">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="203"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="274"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="322" mass="34522" checksum="7445F232256839F8" modified="2019-05-08" version="1">MLTVREHSNISFFLKENVLLKQRGSSSIRVIDFGSSCYVHQRVYTYIQSRFYRSPEVILGLPYGLPIDMWSLGCILAELYTGYPLFPGENEVEQLACIMEVLSLPPHHLLIAASTPLLAGVWVGVAPGGVARVGWVGGLDSKGNPRCVTNSKGKKRRPGSRDLASVLKCSDLNFVHFISRCLEWDPSSRMTPEEALQHEWLHPTTSNASSSSSSSLSTTAGGGGGAEKRGGAVNGGPVANVRRQGPITQDSTEDENFSLYTVYKGKRHRDNCALAAESGAKNDSSSSATNSNPAAASSNGNQDGTSTENSLDDSGTFLPPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T708</accession>
    <name>A0A423T708_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CUB-serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002187">
        <property type="protein sequence ID" value="ROT72245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T708"/>
    <dbReference type="STRING" id="6689.A0A423T708"/>
    <dbReference type="OrthoDB" id="6380950at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="19124" checksum="140CC41538F72736" modified="2019-05-08" version="1">MTTSDYVLVGDHNLYSASEANSQWMQIAEIMNHPSYDSNTLDNDIALIRLKTEIQFPSDNKIAPVCLPTAGEMYDSVDATITGWGAQQEGGETLVDQWWWKKTASGSWWELCRGVMAVLDLIGPESTPELHNTLTGFRPRPEVSVRRLVNPPIGKVVRSQSPGQEYTLEGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7H4</accession>
    <name>A0A423T7H4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hormone-sensitive lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002160">
        <property type="protein sequence ID" value="ROT72408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7H4"/>
    <dbReference type="STRING" id="6689.A0A423T7H4"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025:SF3">
        <property type="entry name" value="HORMONE-SENSITIVE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23025">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="340"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="442" mass="47563" checksum="00CB004B750B2E35" modified="2019-05-08" version="1">MSYPLPPTPLHTETSDSAGGNLITGLTIKCLELGIRPPDGLFLAYTPFVFELVPSPARLLAVMDPMLPLGFALRCLKAYAGVPSGGTSLATTPGDATISTPPLHTPKLPATPEHCEGTPEMAPATLDAALEVPQGRVSDTQSDNESFVEVSESDVKEAESLVKSPSFVSEPGSDTLTTVSLTSEASKMDDSSTRKSNGNGSQKPQEKEERSRRYVTEFLEKYVLDSRTDKQGRRVPILRTGSEESEQDDETVLFEAPGVGAGITAKLGRAKDAVVSGISAGLTSFGLKRKESASSPSSPTQPFPKAVAEKRPSLGQILMGKSPERRSSRCSLTEEFSGVEIIHDHYLSPLTAPKEILAKFPPCAILTVEYDFCLDDDVTMAKTLKSLNVPVTIDILERLPHGFLSLSMVSQEAHVGCKRAIYRIQELLGLTEDTQVKENDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T932</accession>
    <name>A0A423T932_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fidgetin-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_008648</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002087">
        <property type="protein sequence ID" value="ROT72944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T932"/>
    <dbReference type="STRING" id="6689.A0A423T932"/>
    <dbReference type="OrthoDB" id="10251136at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051013">
        <property type="term" value="P:microtubule severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031114">
        <property type="term" value="P:regulation of microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19525">
        <property type="entry name" value="RecA-like_Figl-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000022">
        <property type="entry name" value="Fidgetin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000093">
        <property type="entry name" value="Fidgetin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047858">
        <property type="entry name" value="FIGNL1_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="531"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="311"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="341"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00035694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT72944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="773" mass="85100" checksum="BCF9FE7A135AF479" modified="2019-05-08" version="1">MSTFGCNVQETASPAAEDVYLHLWQKKTLEAESGGGQVKADALRFNLAQLHYLKANFNDIDDATVAIKTKELLQDYGRFMDDQKKGLNNYAKPILTLVGKSKNDSKNWKCNLKPEEVIDKYLKPLPDSSQNLKSECKKLAKILNKSQERKSLQSEKFHNMACVSTLSESVTLDDTVGPSFNLMDDDMLDSQESDAGYNVKQSDLFNEERYSTSGSGSNFNRQQLNKNSIQSRMSQSAGPFRSEGNSFDNGIATQRHREKAGTYPWNRGNLSGVSSAGNMGKGRSAGMEKENMENRFGNDQVNIVNGNLERSRQDGLRGSFGGGSSGNVFTSYSQPQQQQQGGSGGGFRGRGGGGSGRYPWNRGAGKQMDDSPNMDDVSCFKTASHQLLLEQMKKSGRGVVSEAAYGSVKRSLGVRRAVNNKFTPPIRREDEDNNFGSGEIIRRCLPQGSSGKGGEGRAGAEESPYAELLTDERLKNIEPKMVELIMNEIMDSGPPVSWDDIAGLELAKTTIQEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTMIGKCIASQSGSTFFSISASSLTSKWVGEGEKMVRAMFAVARCHQPAVIFIDEIDSLLTQRSDTEHESSRRIKTEFLVQLDGATSGSDERLLVVGATNRPQELDEAARRRLVKRLYIPLPEAKARQQIIVNLMANQVHSLTEEDVHRICQSTDGYSGADMANLCREAALGPIRSISFSDIKHISVDQVRPISTDDFMSALRSIRASVSDKDLQMYEDWNKKYGISAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA78</accession>
    <name>A0A423TA78_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008229</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002036">
        <property type="protein sequence ID" value="ROT73331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA78"/>
    <dbReference type="OrthoDB" id="6347053at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="56251" checksum="1BA5ADCFA7556282" modified="2019-05-08" version="1">MLVKGFRLLLRPNSRVICSPIMAKLSTKPNPENESSEGREFKWLWPAYREVEMFKAGHDIGCKHTGGRYRYNTVKPLDPGHVEQALRHYQRKIQNCRCFFKEREGKMWVCENPNPDIDFEYLEGAESNDVIKQLTGEPFLADWTPTWKARLIPVPADAPCHIPEIKAAFPYQYDLVMMPHHALIDGFTMSFITGKLVGLLNDVIAGRPIDDEPFGVYLNNEEIVKMDEEIAKDLEKEPEKIEAIKQELLACDTPPILCKAFPPPGGKPSTDFVYRNINQKSLASFTAKCKANGVTFNSGLEAVINTAIIEMVREAGVESHHMSINLATDLRRYMKRRPLPILGLHVRPTVHRIETPSNVRDNFWDYTKKLHQRLSVFLKSGEAIHQNVVREMTLPQLPPVEHHAAGPKALRDYGVTNVGDLTVLIPGVGEHLQQTDLAMFSCTHYSGFPMLHQIYTFRGHSPYTLSYDTSYLAEDTAVQLMDRILALMDELGTSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBV9</accession>
    <name>A0A423TBV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pacifastin light chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_007546</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the protease inhibitor I19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001957">
        <property type="protein sequence ID" value="ROT73970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBV9"/>
    <dbReference type="OrthoDB" id="10026631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029856">
        <property type="entry name" value="AMBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008037">
        <property type="entry name" value="Pacifastin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036201">
        <property type="entry name" value="Pacifastin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46676">
        <property type="entry name" value="PROTEIN AMBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46676:SF1">
        <property type="entry name" value="PROTEIN AMBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05375">
        <property type="entry name" value="Pacifastin_I"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00215">
        <property type="entry name" value="VWC_out"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57283">
        <property type="entry name" value="PMP inhibitors"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51446">
        <property type="entry name" value="PACIFASTIN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 9" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 9" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="78"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="213"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="253"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="302"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Pacifastin" evidence="11">
        <location>
            <begin position="342"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="413"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="10">
        <location>
            <begin position="484"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="site" description="Reactive bond" evidence="9">
        <location>
            <begin position="150"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="site" description="Reactive bond" evidence="9">
        <location>
            <begin position="280"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT73970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="953" mass="104738" checksum="4863BA4D5BB05196" modified="2019-05-08" version="1">MGRSGSSTATPVCALTREHVAHGRLVMFHGQQNCPLMQCANPGHSGKKNATRVGVPTLGGRVACTVKACIGTTENADEPKCTDGSKWKRDDCNWCDCVEGKIRCTQRVCGHPTPQIRQFEEKEEMCTEGSRWRVSCNWCSCMNGTGGCTKKGCPPDFEERTDAPECEGTSRWKKDCNWCNCHNGRGICTTRACISTPAVHSQPTVEVTVTQEEPECTEGSRWLQSCNSCRCIEGKAACSKRRCIPDFEPSPDEPVCHGNSSWRVDCNWCNCANGKAICTYKACGVQRPQAPPVAVTVTREEGATCTEGSHWRLDCNWCRCIKGQGACTKRGCSADEAPGPDDPVCEGTSSWKRDCNWCNCEDGKAVCTEMACDLEGRSFGSVGVQENPTPKPCINGTTCTRRFCRHPPVNPICNLPSVYPDVDRCRGFESLWTFDSYEGRCVAIVYGGCGGTENLFETKAACEAKCTRAAQGSLRSAGSQEDKCQLKLESGPCFGLFYRYGYNSANGRCEQFIFGGCGGNANNFETAQECQEQCGGGVPVSDSSCDRTKCPWKRWAHYLVKNCIPQYEDGACCPTSFSCPPSDSVIPDPTKCYYRGNFYENGEEVPVEDVCSASCRCHAETAPQIHCANIECPSLFRPPRPGCRLLFSPDQCCSTDEECRMYFLDPAAPPDLETRAVGCSWGNKTYQIGDKMYFDDFQCQSCVCTPEFTSPTGPGCSKIDCGFEFRYTSRLADGCVPIFFEDKFVPLTGCVLETVASHQLMQYSSNKEFHHRKKDDQCHLGELTISHGSKLNINNCRIDCRCTTPPELTCVQYRSCELAAEVTQPKDCPEVNCPPACQTITDVATGCPVCSCTKYTFSCEKKECPSGCRTDFDSKTGCLTCKYYTGRAPCPMDCAIRYVTDPETGCEKCECDPANPGHPFGLPLVQIAQRSIRKTPMPHGLCIRYVTDPETGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDB7</accession>
    <name>A0A423TDB7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001897">
        <property type="protein sequence ID" value="ROT74445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDB7"/>
    <dbReference type="STRING" id="6689.A0A423TDB7"/>
    <dbReference type="OrthoDB" id="5988548at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF101">
        <property type="entry name" value="POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="91"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25696" checksum="3FC6C0C40B6C210C" modified="2019-05-08" version="1">MDTGFKLDYPPEELQKWVSRPPVPEHPGLPGEMGKPVRTPPGQEALMKEKFKLNQFNLLASDSISLNRSLPDVRLEGCKTKKYPPLMPTTSIVIVFHNEAWSTLLRTVWSIIQRSPRPLLQEILLVDDASERDYLGEELEQHVKTLPVPVRVLRTVERSGLIRARLLGASQVKGQVITFLDAHVECTEGWLEPLLARIAEDRTRVVCPIIDVISDEMSTTNSPIESSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFV8</accession>
    <name>A0A423TFV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative lactosylceramide 4-alpha-galactosyltransferase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006129</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001784">
        <property type="protein sequence ID" value="ROT75352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFV8"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="8">
        <location>
            <begin position="226"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="370" mass="42359" checksum="E54CE92AEAB1A616" modified="2019-05-08" version="1">MKRCLGYILMTAMACAMMTYYFMNPQISSYSFRLNIISEPSVNQDIPWWREVLCKGTDQQGARMLELPWLQRDVEPPESDSNIFLVETACKTTPSFRVWCAIESWSRPLTSQVWYVMTSLTVNDTDGLVSRLKEQYSNLRVVGADVEKIFEGTGLHDLFSSRKWIMKAKWPAVKLSDLIRVAILWRWGGFYTDTDTVCIKDVSPLRNIISFSNNKRNHISNGAFQFKHHHKFLELLMEVQTKRFKNPQQPASWASLGPEAVSTVAKKLCNITDWSNLPGSKGDPVECGDLTLLPPKYLLPLDWTQNKRLFAKGSGEYFFSKFNSTYVIHLFSALTRNKKLHIGENSIYEVAAKTFCPVTFKHATADSDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG29</accession>
    <name>A0A423TG29_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase RNF10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RING finger protein 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_005981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNF10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG29"/>
    <dbReference type="STRING" id="6689.A0A423TG29"/>
    <dbReference type="OrthoDB" id="10064108at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16536">
        <property type="entry name" value="RING-HC_RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039739">
        <property type="entry name" value="MAG2/RNF10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983">
        <property type="entry name" value="RING FINGER 10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="610"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="677"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="749"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="621"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT75439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="782" mass="86023" checksum="13BD2F8D9DD6E38D" modified="2019-05-08" version="1">MDTQPAMDKKAMAKAPPLPSKNGSEGTLKDYGGKKCASQYARKRDFDRPDPGKKPVAGRGGRAGQRYVRPREKTGGQVESSNSNVESGSLYRMGGKKQNITHLMNWWGPSHRSQTGHGHHQRGGTRVRRYSSHTPKYSKEHYLQANCQFVVKEGEDYSVYSADPDLLVEWKLVEEVRLHVSEAPACPICLHPPTAAKVTRCGHIYCYPCILHYLALSDDKWRNCPICYVPIEKDELRSVKAVCHKDFSIGEEIELRLMRRERDSLLPMPAASFSQEVLHEMQRIGSPNAATPFAKLIIASKEEVYKHILEREERDLIAQLVEEGDQPEACFIDEALSLLHIRREALFSSGTKDGKSVKKTIEGMHSLSLSSPEEELCAVKMLSTEETGPPSFLMEQESSTLLEPSPTTDTKVAGLKLGTETTVTADDLDISQLQPGNTPTPAHGQKNVPKSTYYFYQASNGAHIYLHTLNVQMLVHEYGDLVNCPAVFRAKVVDKESVLMTEELRQRLRYLSHLPVACSFDVVEVMLKHPLVSKLTTANYQEKIDARQHIRNKRAREERKIERRVQAEQDRMMGRSRGAANLKVNSFVHFPSFAEDFPTNPGLEATDGSVTIPGKPEGSECSASPTGDSLYGSSADTSGSGMSFAKMIREGQSKVHPLPNEPACRAGGLWPSLGKAAWPDPVNPGKNRTEGGSTWAMKSNAGHGGVGAPSANSGLLSEDEDEEGAPVPEFKHAFSDAIAKAFDAAVLKPTGQNTELEVSTAGGKKGKKKKKKVLLFSSGGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THP7</accession>
    <name>A0A423THP7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulatory protein zeste</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005542</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Self-associates forming complexes of several hundred monomers.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001716">
        <property type="protein sequence ID" value="ROT75897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THP7"/>
    <dbReference type="OrthoDB" id="6377268at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028002">
        <property type="entry name" value="Myb_DNA-bind_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13873">
        <property type="entry name" value="Myb_DNA-bind_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="4">
        <location>
            <begin position="162"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="24124" checksum="3A7E5084DEC5DC9B" modified="2019-05-08" version="1">MTHNGAPRYLKASAIVGAAFALFLLLLNHDLGSYVGPLMPKKALLLLPKIQNAHTYTVPSASASPSTPTSFEEEGVARRFQEREEFKKEMCREMNTSGKILTNYFMYYNKEYKLLLCAPPKTGCSSLKRHLLRLVGFPENINVHSDQARRAIAVRMDRLPVLSECQRIVLLQLVEDRPVIQDKSSSLGLNEKKRKAWEELTACFNARNPEETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJJ9</accession>
    <name>A0A423TJJ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">F-box/LRR-repeat protein 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">F-box and leucine-rich repeat protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_004768</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FBXL7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001627">
        <property type="protein sequence ID" value="ROT76640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJJ9"/>
    <dbReference type="STRING" id="6689.A0A423TJJ9"/>
    <dbReference type="OrthoDB" id="423607at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22120">
        <property type="entry name" value="F-box_FBXL7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000122">
        <property type="entry name" value="F-box/LRR-repeat protein 7 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000018">
        <property type="entry name" value="F-box/LRR-repeat protein 7 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382:SF80">
        <property type="entry name" value="F-BOX AND LEUCINE RICH REPEAT PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="11">
        <location>
            <begin position="31"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00070271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00077966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT76640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="46201" checksum="C58EBF0A3CE2DE59" modified="2019-05-08" version="1">MSPSVYVGGGTLGRTTDQLLATYKGKRVARSSPFDKLSDELVVRILSFLPTNAVCQCARVCRRWYVLAWDPRLWATITLTSDAIHADRAIKQITRLLARDSGGCVHVEKVILNSCSRLTDRGLSLIGRRCPELRHLEIKGCVNVTNIGIFELVTQCVNLDHLDVTGCHQITCIHLTQQGNVEPEPMHSRQLYLQYLDMTDCYALEDQGLKVIVKNCPQLLHLYLRRCINITDAGVKHMASYCLMLREVSVSDCVQITDFGMYELAKLGPNLRYLSVAKCDQISDAGIKQIARHCYKLRYLNVRGCEAVSDDSMEMVARSCPRLRALDIGKCDVTDNGMKLISEHCPNLKKLSVKSCDMITDRGVQYIAYYCRGLQQLNIQDCQVTIDGYRTVKKHCRRCIIEHTNPGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMI3</accession>
    <name>A0A423TMI3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_003698</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Part of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
            <location evidence="9">Nuclear pore complex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the nucleoporin Nup84/Nup107 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001500">
        <property type="protein sequence ID" value="ROT77642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMI3"/>
    <dbReference type="STRING" id="6689.A0A423TMI3"/>
    <dbReference type="OrthoDB" id="3098at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3450.20:FF:000001">
        <property type="entry name" value="Nuclear pore complex protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007252">
        <property type="entry name" value="Nup84/Nup107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003:SF2">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13003">
        <property type="entry name" value="NUP107-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04121">
        <property type="entry name" value="Nup84_Nup100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="585"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT77642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="689" mass="79411" checksum="2D3D659F12463D26" modified="2019-05-08" version="1">MGEEENNRDSPMSGEEPTTDLTVVSRLYDTNRTIRVAQIVIDWLEKNAADDFDRKFYDRVEYFDDTHIGWENTLKTLKSESSGVSIPFRGTRSLVTSLDPDAPVRQGKPLHDLDHEDEMRLMRCVFVYVRSGQVAAAEELCVKAGHHWRAATLEGWKLHHDPNPLNPSQRNPISGNPYRDVWKAVAWRAASDERLPQYERAIYGALCGHLQAVLGVCHEWQDVLWAYSRTMVDQWVEEQLRRAATHLRPLHPLPKDFPEEKLSMKALFEAVEQRPEVQQQRHNNPYHLLQKYIILDDVESLLREAHVWLNDGLAPHLLRCLTHVVLFLRKIGRISQQQESLCTDILEACVKESIERGDVEQVAWYTSVLPVWLQVEWYARFLHNISDDHHRRHALQLAATVGLDTRAITSTVVTNIRLSGSRDPENEVVSETTGDDRVKISAIDWLLYDPKQRVEALRQASALLRTLLISRKIETGSRDLTTQSDNIVREYLCIRTFLDAQDSFTDWFDHYHQKRPQPPKKPTVGSNFSQQVAYEQAEQQHNGELDRWKHTLSLITKTACDRLYNVLLFPEGGWLVDSGLEDQDVDTSAKDTSSSRELRLDNQEPDRAQQMSVLRSIYIPQVTSLLQNILHSTENYKESVRLADIIASEQHQLYKAFGSCELQQFLIKLQETSRELLDCNCDALGYPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMQ8</accession>
    <name>A0A423TMQ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mucin-1 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001490">
        <property type="protein sequence ID" value="ROT77716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMQ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="518" mass="57212" checksum="0E4A9E7A18462272" modified="2019-05-08" version="1">MSYGRPRWGSLHIAPDKKAKEEGNQPPPHPRRRENNPLPHPRGKPPHHPSQEEGKPPTHPNPLHHPRGGNPTPSLTQEKGKPTPSLTQEEKGNQPLPHPRGEGNPPLTHEEENQTPPSPRGGKPTPSLTKRRRGNQPPPPPKRRETNPLPHPRGDGKPAPSLTQEEMGNQPPPHPREGKPTPSLTQEEKGNQPPPHPRRRRETNPSLTQEEKGNQPPPSPKRRETNPLPHPRGGKPTPSLTQEEGNQPPPSPKEEGNQPPPSPKRRRENQPPPSPKRRETNPLPHPRGGGKHPRAAAVRSSGLLEPRRRELAGKKHQGQAGKASKQTSKREQAGKQAASRSEQTGKQVRADRQVKSEQAGKQVQASKVRGRQAKRQAGQRQQAGQSKGSEQDRQGKRQAGQSRQTSRSEQGQSKQSEQQVSRSADTSRSEQTGKQVRADRQAGQSRQAKQVRADRQAGSAADRQAGQSRQASRFKQVRADRQAGQAGGKQAKQTGKQVRADRQSSERARSEQARKQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN11</accession>
    <name>A0A423TN11_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibrinogen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_003449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001464">
        <property type="protein sequence ID" value="ROT77851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN11"/>
    <dbReference type="STRING" id="6689.A0A423TN11"/>
    <dbReference type="OrthoDB" id="6361951at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.215.10:FF:000001">
        <property type="entry name" value="Tenascin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020837">
        <property type="entry name" value="Fibrinogen_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF327">
        <property type="entry name" value="FI21813P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00514">
        <property type="entry name" value="FIBRINOGEN_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019547638" description="Fibrinogen C-terminal domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="5">
        <location>
            <begin position="192"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00053344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT77851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="411" mass="45540" checksum="F9427F2EE7FADD80" modified="2019-05-08" version="1">MKPATVIRGLGNVFMLVTLVMGKPTSEVNVDSSGSVVNLQGSDPGRAQITVDMPGQVNMNADGQALVLLLSEKGQGLRVDINGVLVSDLIDDNDLTTSAPEQVTTPPVYQINLQCPRRLNLQDVPQTSQPPDVSTSPRRLNLQPQTSQQCPDVSTSSPRTSQPPVCKVFQLCPDVSTSTCTKPPVQPTTQGPPKINHDRNCLTKKMEGYTSSGIYTLQPFDCCPDRNVDAPCDMTTDGGGWTVIQRRQENPSHQEDFYRTWDEYVDGFGDLTGEFWLGLDNIHALTNQTNYEIRIDLEDWDGTAKWAQYSTFLVKDRASNYKLQLGSYSGDAGNSFAYHNMMPFSAKDGPVLNECPKTSHGGWWYNSCHYANLNGVYRNAFNLDGDSIAWFSFRGPNYSLKFSEMKIRPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQ72</accession>
    <name>A0A423TQ72_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001354">
        <property type="protein sequence ID" value="ROT78616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQ72"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1107" mass="119748" checksum="A678879804EC95C9" modified="2019-05-08" version="1">MSRGRIGGSSATGRFVTRHSGSAVTAADDYCHFGWSAHTWGPPPAALGYEKWGGSTFLITIPWSLSPFILSFHFLPCFLFPSSPLLFSFVLFSLSLPFPFLSFACLSPSLCPVDFSSTFFFSLVYSPLSFSPYFSSFSRHSPFLPSPSSSPSFHLLSLSYISIPVFSPSLYLSFYFLPLILPSSIFLLPSLLSSHSFLIPSLFFHTLPLPSPLSPILFLPVILSPISSFSSSPFPPFSSSLPSLPFILSFSFLPFSSLSSSSFPSSLSVLAHPPLSPFFPSRPLPPFPFLLSSFPSCPFSSLSSPPSSFLSFPSRPTLPSPFFPPFLPSLSILFLLPSFHVSSFLSPFHPSFPFPSSHSPTLPSSPCFPLSPLSFLPFTLSSYLFPFPPPILLLSLTPSSPLPSRPPPRHSPLSRLLFPFPSLSPSLPSFLSQFFLLISPPPFPLFPLVPSRHPPSLLLFPSFPPFSSLFLPSFLPILPPYSLLPLFPLPLVPSASTLPLSLSSPLFPPSLPFTLLFPSSLPPFLSHFSSLFSSLFPLFLFVPSRHLSPLSCSFPPPSFHPLLPFLFSFLPPILSLSLLPLSPLPSRFPSLPSSPLFSLSFSSFLPFQFFLLISPPSFPSPSRPLSPFLPLSSLLSFSSFLSSLLSPSLSSLFPLSLSFPSLASSPSTFHPLFPPSLPFTLSPSSLPPFLPILPLSLPPLFPLSLSVPSRHSPSLPLFPFPPFHPLFPSFLFPFSSLISPPLFSLSLSSPSAPPSLSSLLFLLPSLSSSLPSFFLPPISSLSLLPLSLSPSSILPTSLFSFFPSSSSFPSLFTSLFLPSFSFLPPISLLISPPFFPLPLVPSAPLLPSLLLPFPLPLPFTLSPSSFPPSSHFSLSLSLSLFPLSSRPSLPSSPLLLLFLSLPSSLPFSFLILLPSLFPSPSRPLSPFFPSSSSFPSLPSFLPFSPSLLLLFPPSPSLSPLFLLFPPLSPSLPASPSFHHFSFLPPFLLPPHSPSLILSCPLSPLLSFPLGATLPLSLFSPSLLFTLSSFLPFSHSFLLISPLLSPLPLVPSRHSPLSSLLFLLPSLSSSSSFPSSSFLLPYISPPPFPLLSSPRALSLLVSSQSPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TS24</accession>
    <name>A0A423TS24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001270">
        <property type="protein sequence ID" value="ROT79231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TS24"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="46299" checksum="BFA997906D86432C" modified="2019-05-08" version="1">MSVALSHPLSLSRSPYGLSLSRSVSLFLSSFFLSFFSFLFLSFSSPLFLFSFCFFPPLSFFFSPSVFYSLFLSLISLFFFPLLLSSPLFLLFFPFLLLSLLLFLCLSLLLSYSFLLLFPLCFLSPFLFLPSFLVPFLFFLFSFSPLPLLPSLLFSSSPSLFLFFLPFSPPLFFSFFLFFFFPLHLPFFSGPFSLSFYPFCPFLIFIFFFLPFPSLFFLLSFFFFFLSFFFFFLPPFFFSSFPPFPLPFFFFFSPLFFFPFSLFFSSFFLFPSSVFLFFPPSFSFFFSFLFLLPFFCLLFLFFLLILSLLSPFFSSSFYFFPLLSFLFLSIFFFPSFFSFFSTPFSFFFFFFFLFPSFPFLFPSFLFFFPFFLSLSLFFSPFFSFLFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUS4</accession>
    <name>A0A423TUS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001145">
        <property type="protein sequence ID" value="ROT80180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUS4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="114" mass="13764" checksum="B3862CF0F773B14D" modified="2019-05-08" version="1">MVFWGGNASTFLETVQIVRIGSFLQKVTCTSLKFGLFLKFYWKQFVEVNLILRIRQRNETEEDWRKRNCYCFHQEGNSSKSSVWKQDVNWTDFLFDENTCRHFKDNALRCRCED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWF0</accession>
    <name>A0A423TWF0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamma-tubulin complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_000458</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001068">
        <property type="protein sequence ID" value="ROT80791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWF0"/>
    <dbReference type="STRING" id="6689.A0A423TWF0"/>
    <dbReference type="OrthoDB" id="6344705at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22572">
        <property type="entry name" value="GCP5_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059169">
        <property type="entry name" value="GCP5_N_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF33">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="264"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="669"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="741"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="762"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT80791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1011" mass="113630" checksum="C1E07FADA13D8EDF" modified="2019-05-08" version="1">MSLSMQGKFDELSKELINHVLGFEEGEENFIRSEQYVLSNLLYHHCLAVNSHNVRRSIDGLVLKFSIHGQHHRSQQLQNLTSKFLASPFFKDHDELDIEWSLLSLLLHLSNSPTQVPVSDDEILLTLNKSSSPVKSLHLAEENIDWVAYLRQGEPEYVVGVEQPLSYSPVKNSSVAVKDTCNLPRAPTAQELLEQSHRAQSWLAANTHTQYWGSKKYQQCAPLSSHPAANVAKLWETKCGSRGSQQLSEWAVMRETVWVLMCPSTSHIFQYNADQGFVVHPEITIPSLTPGAAKRLLEELCLPLNQLLEIDAFLKKCEVPSVDPPFPVTLQAYATGIRLWRHRFQSHLATIEDQIKKQESTCTLSWLEGELYPWLRTLSAIATVHSMAAMRPEISPREAAVRLINGLCDGVESAGEPGVRCVLLRLLLHTLRHYLSIINNWLLHGSLVDHAQEFIIQRSESVKVTDETFWHDAFILNPHHQSEAKQSRRSSLKFLSPLVGALTTVGKSRELLAVLDVEPLPRSSAILYLHQKSKMDPEMVLEEVIIRHIQDALYGSSEKAKENTEGNEGVADDSSALTEVDQHMVSNYQQVDPLLLAAFIGDAGTPASPTMTAQKDSVTRMIEDMAEVPRAISVVSLLSSAISPLIRKKEEELSARLTQVLLEKYHMDRHCQAVRSILLMEAGDVMHEFYSHLFSKIDIGESIDGISLTLHLQDCVTRLVPDLAPLFSVSVSSASGFLNSAEENKTDNQSVPADSMLGKDSNQTKEEEQDKNKLGSDSTTMPLSKAGLPDISINYQVPYPVNLLLSEKVLSQYNILFRFCLSIKRATNGLERLKFKDLASWNAVIGSGSNTEDAAGPLLSRLHRLQLLRLWLLCFTRELHDHFANTVFLPFHQTVEKLFLSRPSLNVIITEHEKLLNRLITNCLMGSGKTSSPLQIVLNKVFWLSQRLGQLWRRDIGRVTCNELSAIETQYAQVHRYLVNFLTRLTTTNYLPHLEGLTRTLVDTVPLLTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1B5</accession>
    <name>A0A423U1B5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dynein heavy chain 7, axonemal-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000817">
        <property type="protein sequence ID" value="ROT82479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1B5"/>
    <dbReference type="STRING" id="6689.A0A423U1B5"/>
    <dbReference type="OrthoDB" id="6373483at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF36">
        <property type="entry name" value="DYNEIN HEAVY CHAIN, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="2">
        <location>
            <begin position="184"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="44347" checksum="09E53484846F7A7C" modified="2019-05-08" version="1">MTINICTFHLRSHSGHNATVSPSTSSVEEGRDVDPEMLEYLVGRVFYGGRVHRAEDQQGITGLDRPEIFGLPAGVQQLQEIEAGQRFLTVLATVGGAQNLQGESERISKDEVKRLKKMSRMSVALGRLKGLELYGRFRQLPAPIEGEAQLDECEERDLRDVMRREINKYNAIVLGITREERPGDGTEEVISAVNLGHTPASWRALCKHPTPGTLHAFLQDFHARVDFFQTWLNNGCPKTYWLGAFQFLPAFLTTILRQVGQSTRRPLHHLTWGFHMTDEPPPEMPEKRVGGTVIPRADTAAPLLSMIPTPTVQTGSLPCEGRFTLYHSTALNPRFTDTRDLEKQQKDLNHHADRPSRCDHPSTEAQQTRFSDEFQNIKDSTSLDLQLGEETCQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1Q8</accession>
    <name>A0A423U1Q8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein Wnt</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024201</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Ligand for members of the frizzled family of seven transmembrane receptors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Secreted</location>
            <location evidence="1 8">Extracellular space</location>
            <location evidence="1 8">Extracellular matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Wnt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000795">
        <property type="protein sequence ID" value="ROT82629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1Q8"/>
    <dbReference type="STRING" id="6689.A0A423U1Q8"/>
    <dbReference type="OrthoDB" id="5945655at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005109">
        <property type="term" value="F:frizzled binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045165">
        <property type="term" value="P:cell fate commitment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005817">
        <property type="entry name" value="Wnt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027:SF81">
        <property type="entry name" value="WNT INHIBITOR OF DORSAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12027">
        <property type="entry name" value="WNT RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00110">
        <property type="entry name" value="wnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01349">
        <property type="entry name" value="WNTPROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00097">
        <property type="entry name" value="WNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 8" id="KW-0879">Wnt signaling pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="119" mass="13318" checksum="1C5FDC2D74389437" modified="2019-05-08" version="1">MPLAESIATGAQTGMSECERQFTWDRWNCPPQAFTKLHEGEPATRERSFMHAITAAGVVFTITKNCSRGELEGCSCSGGQGGRRRDWKWDGCSENVEFGSRITSSSWTRSRQARTQRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U294</accession>
    <name>A0A423U294_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Centrosomal protein CEP104 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000773">
        <property type="protein sequence ID" value="ROT82823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U294"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048739">
        <property type="entry name" value="CEP104_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21038">
        <property type="entry name" value="CEP104_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomal protein CEP104 N-terminal" evidence="2">
        <location>
            <begin position="35"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="23745" checksum="05E054652910437A" modified="2019-05-08" version="1" fragment="single">MTKSSKSSLCLSLPPGEDDGGRAKELLQQGPGVKGWASARFCIYPQELVFQLEERCNLSRVQLLAHQHLIPEKIELYIGDVPPGREVALYNVRFAQLGYITLSDNEHSQFKARELKSVTVDCTGTFLKLVLHKNHINRLNLYNQIGLVAINILGNEVETNNNSVSPDGEGGQVPSARDQEVPIYHDLAFAMYVDTQVAATIRTLEDRRLAAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2R4</accession>
    <name>A0A423U2R4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative EF-hand and coiled-coil domain-containing protein 1 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000754">
        <property type="protein sequence ID" value="ROT82986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2R4"/>
    <dbReference type="STRING" id="6689.A0A423U2R4"/>
    <dbReference type="OrthoDB" id="6359872at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031601">
        <property type="entry name" value="CCD48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15799">
        <property type="entry name" value="CCD48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="274"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="540"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="607"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="673"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="722" mass="79213" checksum="24691799646D899D" modified="2019-05-08" version="1">MDSGRSAGAGMGGPRGLVAGVKAAFRSRSRSEKSRSRSRSRCENSKTDDHDEVRPGKGERAPRSPFLGWARSRHKEQPKAKEAAKAKEVAGGATEASGPCSLLQAERLSLHSSEDYWHTSEDLRDIRRGTYTSFRSDFYDSKYAGEKENEKTLDRLRLLVDDGAATRLQDSRERTGRLGRYVNLPVHCAGVAGQVPGESSARAGAGGLALGVNASNHRVASCGVAAALESQGPRYYDKEKTPEAVRGSWLKSALSYNLEVPESPRNEVIVLALGIDQYIEEVFRFLDRSGSGRVGIEDFHALCQVLGLAESEGLPRKGQQRCQCLGSKLTLNGSLDNSLLNNEVPGDKVCPIHLNFSEFHDRLCECFVKGAQTETLSPLASRRPCNPRLVTSVVHIQRRYDILEKISKSIAEINSELEGDAKRPPAECPTAASACCTSRQPAHVDRNSNISPQPSYSETCLLKRQVLLQQQELQCLREVIEDMRVALQNSDAENLSLQVQMARSSAPSRRGSEHDLCLTDEEDTIDDLVRQLTELSRPRNDLSSIPVAEVAPQPQEAPKEAPQEALQADDPKCKMEAQETASRLPEPPGSPKDAHNTAFVSGDLSLEAELQATYEALQAAREEQEATQADLQRTVSELQQREADLKGAELSLQASYTALEKVQYDSHALVMEVAETRSLLEDTKERLAGALEELAQAKSTMQEQEAQLTCAKESLEVLQNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2S2</accession>
    <name>A0A423U2S2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_023850</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000754">
        <property type="protein sequence ID" value="ROT82988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2S2"/>
    <dbReference type="STRING" id="6689.A0A423U2S2"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000009">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="85"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT82988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="14989" checksum="2BD3AA4110AB5D99" modified="2019-05-08" version="1">MSLMAKGGGDGPGFVGIRFCQECNNMLYPKEDKENKILLYACRNCDYKMPTENNCIYVNKLMHEIDELRHINPEVIQDPTLPRTDDHPCPRCSTRDAVFFQAQTRRAEDEMRLYYVCCNSECTHRWTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U505</accession>
    <name>A0A423U505_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Crustacyanin subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_022983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U505"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF15">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018824911" evidence="3">
        <location>
            <begin position="17"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="4">
        <location>
            <begin position="80"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT83800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="162" mass="17990" checksum="22FCDE1F2E9939F8" modified="2019-05-08" version="1">MKSAVFFVAFVAAVAADKIPDFLVPGKCPAVNEKALFEQQIPNHSKDGSKFIAKSTGINADGNLMRHNGQVLPMPLGDPHLSIDYEGSFTAPYVILDTDYENFSCIYSCVEFNYGYYADFAFIFSRSPSLSDQYLRRCEAAFKEIGVDVSRFEDSPGFELPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7F7</accession>
    <name>A0A423U7F7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_022200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000520">
        <property type="protein sequence ID" value="ROT84609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7F7"/>
    <dbReference type="STRING" id="6689.A0A423U7F7"/>
    <dbReference type="OrthoDB" id="10257076at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="150"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="282"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="253"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="422"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="49520" checksum="3F0850ECC98EC2DB" modified="2019-05-08" version="1">MHWAGWSGHWRTLEALAASGADVDPVCNKGNTPLHDAASNGKLLAVGALIGLGASTSKKNKDGKTPQDLLGTTSADRVFSMVMAAGNQTGDMESWFSLPCFAPQCWCQAGRRGRWPPLLLFISRELKRMFFLKSLNVLCEWPFQAKESARRGGRCRSGRSTTRKRRRRPPCRRSTTRKRRRRLQKEYDSKAAEAANLQKEYDSKAAEAANLQKEYDSKEAEPAEGKRRQKLKEKEAEIKQVEGQVKKARRDRQRGEREAGAEREGFNAQIAGLEERIATLQSHLEEESRKNRALTTQIAEKESELTQAELESELKRRDKKIEDLKSEEEDSLLKRMMVSAPRPDASLSPPRDPEAPGAGEPSAVGGRRRVRGAAGSGDTPPAAARDGAKAAAGGGDKPRQATGRKGKARKAPEDDEPLSAAGRDERPEAAGTRGKESPQEDSDASTLEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8F0</accession>
    <name>A0A423U8F0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative choline/ethanolamine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000465">
        <property type="protein sequence ID" value="ROT84941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8F0"/>
    <dbReference type="OrthoDB" id="6378979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681:SF1">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="27"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="35915" checksum="110BBC740C9EF236" modified="2019-05-08" version="1">MSPSATLAHTSRLPSAGDSSMPTTNIAASGPPHPQQDSRFQHVHIDIVGPLPMDDGYSYILTMIDRFTRWPEATPIRDITAATVAKTFFNTWISRFGTPDTVTTDLVAQFESELWRHLMILLGSKRIRTTAYHPCANGMVERLHRHMKQALTSSSPNRRWVDQLPDVFLNIRTSFKEDLQCTSAEMVYGTTLALPADFLVTASNFEPGTFGKQLCERMARVRIQPTRPTRHQYIYMPPGLQDCSHVFVRKHPRPPLCPLYEGLFPIIRRGDKAITIRRPKAEDTVTIDRAKPAHLQQPFRIAKVCFAAAKLEGECCSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBA4</accession>
    <name>A0A423UBA4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000148">
        <property type="protein sequence ID" value="ROT85953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBA4"/>
    <dbReference type="OrthoDB" id="10065127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF31">
        <property type="entry name" value="FI18007P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019467098" description="Chitin-binding type-2 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="39"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="116" mass="13854" checksum="FA7491A6B0D913F9" modified="2019-05-08" version="1">MLRQLAVISLVSIAVTLVYSMPSLHRSKRWEEFPNVTFTFDCTDRPVGFYADQEFNCQLFHMCDEDGRRIPYMCANDTAFNQEFRICDWQYNFDCSQAQNWFYLNELTYVTDPPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSA6</accession>
    <name>A0A3R7LSA6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004070">
        <property type="protein sequence ID" value="ROT61627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSA6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="59043" checksum="1A94AD7285849F52" modified="2019-04-10" version="1">MYLSSLPPPLSAVAPPPCPLSLSFSLPPFPFFFLPYLPISISPSPSSHPPFPNSLLSLSPLFPLLSSLSHFPIFPLSPFPSFPHFLPSPFSPLSPSSSTSPLPPPLLLPILSLLSSPFSSFPQSLLFPYPILPPFPLSSQPLIAISLPSSFPALLLSPPCLISPLSFVLLFAFPFCNPPTHHFHSASLSPLSHSRLTFLRRSRFTFSSSRLTSSCTFSSLSSHFLLLSPHFFSLPHFLHFLLTFFSLSPHFFSPRSLFRLTFFHSRSSLSSHSRLTFLYSRLTFSPLASLSSHLLTFPHSAFLLSPHFLRPLVSLSPPSRLILFSLLFFTLLTPPRQSSSHLLFTSLLFTPLPSLRPPSYFSLSSSPLPPPSSLFFPSSFLLRLFLILPPFSPPFSFPLLTLSLPPLSLSSSSLPFSKPFFSSSFTPLSLPLLLHSLTLFLFPHPLISPFSSPPSLPSPNLPLSSFPSPSLSLPFPIPSRSPPPLSLLPLSPPLPSLSLSSLPALPPPLPSLLPSPSPLLLPLPPSLLPLPPPPSPSPPSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LV46</accession>
    <name>A0A3R7LV46_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018164</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003356">
        <property type="protein sequence ID" value="ROT63919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LV46"/>
    <dbReference type="STRING" id="6689.A0A3R7LV46"/>
    <dbReference type="OrthoDB" id="330772at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="10">
        <location>
            <begin position="191"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="49"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="391"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="545"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="209"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="310"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="416"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT63919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="652" mass="75223" checksum="C8467DD1BD908FA0" modified="2019-04-10" version="1">MKIKYASLTYGPESKMAPGVTGTSLVDAIETEIERAKQDLKGVDENLRKLTGRDFNDPNQRGEQRRVRLSSGGRDEEPPAKRRPPGGVFARLGGVVQDQQHVDHRGKPRDFRGEHLAGHPLHSLTISFLVFPSFFYLELPSPLHVFQHGFRPFSAGVHTTSPSLPSSVARPQADMKSRTEAAAELTKDRASRDRNRRMFGALLGTLKRFKNDEAKQKDKEEQRAAIERKLEEKGRVEKEELRRERLELINQRQERKAQIKRLTVKMARVKEHEQWEAHQMKLTRFIRTKSTPSIFWIPRTHTAKTTSLVRASHDNIMRELEEDRLRMKEELEEILGGVRSAVARQGEGGVSTSLDNCPDLLDYEAEEGELVYGEADLSGKDDDDTERMVVQVDGRGEGARKVEIVASQSEEGTSGLERESKGNDSEKENEGKPRDGSRERERDRYNREKDKNREGDRDRKNKERGKEKDRIREKDRDREMERDRGKDRIVGRDKERERERDKSKEKSRDTVEREKNRDTGKNREVQTLYNKETELEATVVHVKIEKDDDDEAGPKASEAAFKKVKEEKPDKAPTSTADKPDVDVASKILREWRRAAATKMMMNQLPCPTVQQVGKIHLPQRAKTHRIRMTRKGKQRFRELVIQLRVILWVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVJ8</accession>
    <name>A0A3R7LVJ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_016391</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 glutathione + H2O2 = glutathione disulfide + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16833"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003065">
        <property type="protein sequence ID" value="ROT65622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVJ8"/>
    <dbReference type="STRING" id="6689.A0A3R7LVJ8"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029760">
        <property type="entry name" value="GPX_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF88">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00763">
        <property type="entry name" value="GLUTATHIONE_PEROXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 9 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT65622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="132" mass="14795" checksum="7A1400B22F13A919" modified="2019-04-10" version="1">MNQLKEEFGDKLEVLAFPCNQFGHQENTTEGELLSSLRHVRPGNNFEPKMVMFGKVDVNGSTADPVFKYLKERLPLPADDSVSFMSDPKCIIWTPVCRSDIAWNFEKFLIGKDGQPSSIALPPPFSLTSPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LW29</accession>
    <name>A0A3R7LW29_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Multiple banded antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002998">
        <property type="protein sequence ID" value="ROT66044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LW29"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="309" mass="33383" checksum="F6D7B20AFC2BB597" modified="2019-04-10" version="1" fragment="single">GKTITPRRAKRNRIPAGEKNPTRGGKKESIRGKKGIIRGGKGHPRGEKEKSTRGEKGINPGGKGINPRGKELTRGEKESTRGGKKSIRGGKGNHPRGTNQPRGKGINRGEKNPPAGEKESPAGEKESTRGEKESPAGGEKNHPRGKRNQPAGKRNQPAGEKESTRGGKGIKKEYRGEKESNPREKESTRGGKESPAGEKESTNEGKRNQTRGGEKESNPRGEKESNPRGKQKESTRGGKGINPRGKRNQPAGEKESTRGGKRNHPRGKGINPRGKEHPAGGRDGKHHTPCKITVIGLLKRHYAPCTLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1L3</accession>
    <name>A0A3R7M1L3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Perilipin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002433">
        <property type="protein sequence ID" value="ROT70399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1L3"/>
    <dbReference type="STRING" id="6689.A0A3R7M1L3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1044" mass="116920" checksum="8FE5AB7A7A11A931" modified="2019-04-10" version="1">MRSRNVVLLFIRDVLLISSDLFPVRVAVTILALAAGCAALPSYKGAPRLPQLARGHSFSFQSSSAAASSASSSSSFSSSGVNFKNAAPSSASSAASSSSSSFSGSFSGGVPHGFPRLLGLKPVFASAFASSGAFGALPTSGTLGSALGTQGLFVGLQTGTRGTSSGAKLGSAGRLSLSYGFPVLEVKDPRLDYTLALKDHRLDSRLALKDQLDSHLAFKDHQLASRLALKDHRLDSHLALKDHRLDFRLALKDKLASHLALKGELASQLALKDHRFESHLALKAHRLDSRLALKDLHPAYTLEVRLSQVDSSQALRHPQLASTPARRVPQVVSTLAPRHPQLAFRLALKAHRLKSHLALKDHRLDSRLALKDHRLDSRLTLKEHHLESRLALKDHRLDSHLALKDHRFESHLALKAHRLASRLAFKDHHLDSHLALKDHRLDSRLALKDHHLESHLALKEHRLDSRLALKDHRLDSHLALKAHRLESHLALKDHQLDSQLALKDHRLDSHLALKEELASQLSLKDHQLDSRLALKDLHPAYTLEVRLSQVDSSQALRHPQLASTPARRVPQVVSTLAPRHPQLAFRLALKDHRLASHLALKNHQLDSRLALKDHRLASHLALKDHQLASHLALKDHQLASRLALKDHRLDSHLALKDHRLDFRLALKDLLASHLALKEELASQLALKDHRFESHLALKAHRLDSRLALKDLHPAYTLEVRLSQVDSSQALRHPQLASTPARRVPQVVSTLAPRHPQLAFRLALKDHRLKSHLALKNHQLDSRLALKDHQLASHLALKDHQLASRLALKDHRLASHLALKNHQLDSRLALKDHRLASHLALKDHQLASHLALKDHQLVSHLALKDHQLASRLALKDHRLDSRLALKDHRLDSHLSLKDHHLDSHLALKDHRLDSHLSLKDHQLDSHLALKDHQLNSHLALKDHHLESHLALKDHQPDSRLALKDLHPAYTLEVRLSQVDSSQAFRHPQLASTPARRVPQGPLWLPGILSWLSVWHSRVLNWPPFRFPGILRWHSRVLNWLPFRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2V8</accession>
    <name>A0A3R7M2V8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003037">
        <property type="protein sequence ID" value="ROT65783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2V8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="473" mass="52577" checksum="8E79160C79F70E8F" modified="2019-04-10" version="1">MTHFILTSPLISLTFLCSFLASLSSPSLFLFILLRPSHLPHFSCSFCRVFSYPHSHVHSPRPSHFPPFPASLSSSSLPLFIPRVPLIPSLSPFIPRVPLISLTFHRSFPVSLSSPHFPPFIPRVPLISSFSFLFPRVPLIPFLPLFIPPRPSHLPHVPPFLSPRPSIPSSFHRVPLISLPFHRSFPRPLIPPFPCSFPSSPCSFPAPCSFSPRPSSISPRLSSPPSLHRSFPFLPFLSRVPVPFPASLFISPRLSHLPPFHRSPSLPVPFPRPVPFPASLFISPRLSHLPPFHRSFPSFPCSFPRVPVPFPRPSSFLASLSPPSFHRSFPSFPCSFPRVPVPFPASLFISPRLSHLPPFHRSFFPSLSPRPCSFPRVPLLFSPRLSHLPPFHRSFPGVSLIPSLPRVPLISHPSPVPFPASLSFPLHSPASLSFPLHSPASLSSPSHSLFIPPRPGFCWATRELIDAQTLGVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3P0</accession>
    <name>A0A3R7M3P0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015623</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002950">
        <property type="protein sequence ID" value="ROT66356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3P0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="41599" checksum="76857AEA9ECCF5E2" modified="2019-04-10" version="1">MVERSSTCLAAPPSAPVSLVLHVRQLTISAPKWLNAIHELREVWWTLSSRDKLVGQPGKRRGLGSLSSATGEHNKVRRVVHPMPVTRSRVIRVAIYGNSAHPSSHVPSLPILPNQYMQTRLSDACTTVDLPFYISPSPLPLSLLSPPSLLPPIASPFHYVLCHSFPFFLSLSLLHLAFLFLSLISFPFFAVLSLSLLFFSLFAFLLSVFLLRLSSFLLSPHSVLSPVLLLAFTPFLPFAFFLSFGFPFFFPSFLFSLSSLPSSRLHFAFPSPFTSLSTSYTRCTSYISFSRFSYLIFLFPSLFPAFLFTASSKQVPHVLLFLFTQFPPSATIFLPVPSSPFSFHFSFIASHLNFFLSASPVCAHISSTFFPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5E2</accession>
    <name>A0A3R7M5E2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative tyrosine 3-monooxygenase isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009157</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002155">
        <property type="protein sequence ID" value="ROT72451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5E2"/>
    <dbReference type="STRING" id="6689.A0A3R7M5E2"/>
    <dbReference type="OrthoDB" id="983542at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043204">
        <property type="term" value="C:perikaryon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004511">
        <property type="term" value="F:tyrosine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006585">
        <property type="term" value="P:dopamine biosynthetic process from tyrosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.800.10">
        <property type="entry name" value="Aromatic amino acid hydroxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001273">
        <property type="entry name" value="ArAA_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036951">
        <property type="entry name" value="ArAA_hydroxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036329">
        <property type="entry name" value="Aro-AA_hydroxylase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019774">
        <property type="entry name" value="Aromatic-AA_hydroxylase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473">
        <property type="entry name" value="AROMATIC AMINO ACID HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473:SF15">
        <property type="entry name" value="TYROSINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00351">
        <property type="entry name" value="Biopterin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00372">
        <property type="entry name" value="FYWHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56534">
        <property type="entry name" value="Aromatic aminoacid monoxygenases, catalytic and oligomerization domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51410">
        <property type="entry name" value="BH4_AAA_HYDROXYL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biopterin-dependent aromatic amino acid hydroxylase family profile" evidence="8">
        <location>
            <begin position="119"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601273-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="459" mass="52456" checksum="183D38DF1AA8289E" modified="2019-04-10" version="1" fragment="single">NGYPARRRSLVDDAKFESTIKKQQKQTWIEEAKRLSCDGELSEEEVFLVQSPCEPDVPQQVALVLALVDGITSLPRIIKTIENFKGTVVHVETRPAPRKGVAFDSCSKVLILGAPPDAAQEPAPGGLHCLQPWFPKHISELDLCNHLMTKYEPDLDMDHPGFADQDYRARRKEIADIAFKYKHGEPIPRIEYRPEEIATWGAVFRELERLIPSHACRQYREVWDVLKRDCGYAADNIPQLEDVSRFMKRRTGFSLRPAAGLLTARDFLASLAFRVFQCTQYIRHHSDAIHELLGHAPLLAYPQFAQFSHELGLASLGASDQEIEKFATMYLVHGGVRSVSRGRRGARVGRRPPQQLRRAPARALRQARAAAVRARQDRRQPYQDQDYQDLYFVSESIEDAQDKFKRWTSQTLSRPYEVRYEPYSQSVQTLDSVQRLEDLSAALGTEVSRLRNAIQKMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5T4</accession>
    <name>A0A3R7M5T4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">G-protein coupled receptors family 3 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_007851</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002001">
        <property type="protein sequence ID" value="ROT73712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="425344at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007206">
        <property type="term" value="P:phospholipase C-activating G protein-coupled glutamate receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15285">
        <property type="entry name" value="7tmC_mGluR_group1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000219">
        <property type="entry name" value="Glutamate metabotropic receptor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.50.30:FF:000001">
        <property type="entry name" value="metabotropic glutamate receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.30">
        <property type="entry name" value="GPCR, family 3, nine cysteines domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011500">
        <property type="entry name" value="GPCR_3_9-Cys_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038550">
        <property type="entry name" value="GPCR_3_9-Cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017979">
        <property type="entry name" value="GPCR_3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000202">
        <property type="entry name" value="GPCR_3_mGluR5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000162">
        <property type="entry name" value="GPCR_3_mtglu_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050726">
        <property type="entry name" value="mGluR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24060">
        <property type="entry name" value="METABOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07562">
        <property type="entry name" value="NCD3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01055">
        <property type="entry name" value="MTABOTROPC5R"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00593">
        <property type="entry name" value="MTABOTROPICR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00980">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00981">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="17">
        <location>
            <begin position="331"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="767"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1232"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="773"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="859"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="880"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1232"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1286"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1400"/>
            <end position="1409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00054813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT73712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1409" mass="155804" checksum="83A852134EB83959" modified="2019-04-10" version="1">MMRDNTQLPRVCVTVVDVEVVLHAQPSARRARFSLHLNAPRRSPLSPPSPLSDGWADRSDVVAGLEETAVGGLSIKIQSSYVEQFDDYYFKLHPDTNTRNPWFREFWQSRFNCSLPGVQESDDRHPEPCSGSQSLKNGYKQDTKMAFVMKAIYTMAWGLHNMQRDLCHGMSGLCNAMVPINGSLYRDYLMNVTFSSMNETVSFDSHGDPPGRYNIMNYQRLENGSFDYVRVGIWDNGSLVVHEDKVVFKFPNNDPPTSVCSAPCKEHQYKSLGGQSDGTQQCCWSCIDCDQDEYLKNETACEKCEPGYWPTDDKTGCEAIPVKHVMWSDAESIVALCLASLGGLATCFTMVVFIRYNHTPVVKASTRELSYIIFVGMMVSYLATIPLLARPSPLSCAVSRILPGLSFSMIYAALITKTNRIARILAGNKKILTRKPRFMSATAQVVITCILISIEVGIITTMLILDKPDVKHTYPGIREVKLVCNTLPRGIMAPMGWDFFLIAMCTVYAVKTRNLPENFNEAKFIGFSMYTTCVIWMAWVPIYFGSDHKIICMSVCTSLSALVTLVLLFFPKIYIILFRPEKNDRSAFKTTTTVRCHIGSGNKASLSRTTERTPSAAVESMYVGSAMLGIGQPQLSLMQRIRSTLGMPFLPPVGILPGEAHPRSLLRREISVWSDVSGSGGQAGGNAVNQNRDIMLRKAYGSQLDLAGVEGWREERSCQTTDDLLDPLIPRLRRRVARAVRENELEVAEGREFFSLTHSWMTSQAEAARSVRNRHDSQGTDEERPITTTIIREDLQTRAVAKEDPGEGPRQEKEKSASEPEEKPGAEGKPGSPRGTEDPPSDKGGGAHGEGKGEKRSEGASQDESGGASQKSPGHGSAQEVREVSPLAKDKPSVLLNKVVEEEEEEDCCDPGLQQKCSAVGKDYTVLRECSTEPQIGDCIGYGSLMPCSPSWKRQRSVSCDNSIIYKKNRVRPFDQATQTDRCPDTQGWIPNGDPSNSLVLVKANSVNDNAHRKRKVGISAKVSDVRGILKTVSFSPAEKENRVSFNSVVCGRNLSRGDELISQESSDEDTEGDSQERVRYVRYRNPVCAEVASGDVSSRIREETLSADSDISDNCELKSIIIKLGCEEDEPDAADKAKSGKNGNIINWRPKLGKNHKLLSQSSDMYEYDTPSATEDEESVIEYPRSGFSNSLDVKETEKEDPDCCKRYSRDNELVILDLLHNTFVPKYQGSQISPDLDSPQCSSAATPPSVCGGTPGHLSPVSQSHFTITPPEYYRNSPTKHASPPESSCSSSQGYGSPQHPCRQDAWSWEASEAQPEAEELTPTASPRPGSSPPVAYRGSHDNPMCCPDEDDPMTKPPGHGSRGAIDPRLARHDTDDDTDESTTPLEEFFRTHGVKFDTTSNRPKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8K2</accession>
    <name>A0A3R7M8K2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001714">
        <property type="protein sequence ID" value="ROT75909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8K2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="560" mass="60383" checksum="F1AD0D5AC614B578" modified="2019-04-10" version="1">MPSRVQYLTSTPNGARTRKDDPRRLHREKQSALGLTCKNENRQDLTRGSHHTTHSSALTADLIAVEPEPASRHANSSSITYTTAQLFGFAFAYCRSTETYAKDNNKRQFARYRVNNRSISISGFRETKKHREQTSPEVLCNPRPFKVSWLQAFDDLPDNGVLIQGIHFFRILIWRGLHKSSLQQPLPISFLPLSPTSIPHSRPRSLSLSILHCPVSLSSTSPDLSPTLSLSPISLARRPQLSVVFISFLPSFLSSSLLSLSYLLLSLSLSYHLAFRYSFLDTVLPLSSLFSLRCVPSASLPPLRSLPPSSLTPPLASSLASLALVLVRSREPPISLSLSLCSRLLSPSLSPRLPPSHSLPHSHSLPLVSSLCVSLSSSLLLVSLSLSLSLSSLPRLHSLPLARLLPYPPPPVSFTSESTRKPNPPPSLPPPSLSPSSSSPSPFLSLKSFTLSLSLLSPSFSSLSSPLPLSLLLSLPPLSTPSLPPSLLPSPSLAFSLSPPSPPSLPPFPPSPSLPLSLPPPLPVLPPSLLPPSPLPSLPPLPSLPPSLLPPSLPLSSLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAV2</accession>
    <name>A0A3R7MAV2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Tyramine/octopamine receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_004569</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001606">
        <property type="protein sequence ID" value="ROT76826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAV2"/>
    <dbReference type="OrthoDB" id="5955450at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004989">
        <property type="term" value="F:octopamine receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15060">
        <property type="entry name" value="7tmA_tyramine_octopamine_R-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002002">
        <property type="entry name" value="Octopmn_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248">
        <property type="entry name" value="ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24248:SF174">
        <property type="entry name" value="TYRAMINE_OCTOPAMINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00664">
        <property type="entry name" value="OCTOPAMINER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01381">
        <property type="entry name" value="7TM_GPCR_Srsx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="14">
        <location>
            <begin position="23"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="203"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="45491" checksum="5D0B9E6777D4FD1C" modified="2019-04-10" version="1">MPVWEIVVTVVSLGVIIIFTIIGNVLVILSVFTYRPLRIVQNFFIVSLAVADLTVAVFVLPFNVAYSIIGKWVFGIHLCQMWLTCDIMCCTASILNLCAIALDRYWAITDPINYAQKRTVKRVMIMIGLVWAISVVICLPPLFGWNDWPDVFTSDTPCILTQERGFVIYSSSGSFYCPLLIMTMVYIKIFTATRRRLRERARASKLNQIPNSGKARLTREEDSAVSENGQNGYNDTSTKKLVQKKRRKKRKSGNKGQASPATPTLAPPPIAETSDLSNPKDEASPLDEKKGADVIVRVNPKDGSQIHQFIEEKQKISLSKERRAARTLGIIMGSFVVCWLPFFLMYVILPFCSTCPVPNDKVINFIVWLGYINSSLNPVIYTIFNLDFRRAFAKILRCPNTTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGH0</accession>
    <name>A0A3R7MGH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004299">
        <property type="protein sequence ID" value="ROT61183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGH0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="46078" checksum="DED184B46EFE1FFB" modified="2019-04-10" version="1">MYCISPTPSNYGLLASALAESPRPIPSSPALMAPRTTPYLLLGPFCLLSLISSPPPVPPSPSPSPTHHSPPLSLPPHPSSPRLLFPSPFHTFPPPLYRISLFFFAFSFFFSLSFLYSSKSLFSFFSFFSFLFYSEPPSPFASLSITLFYLLPPHLPLPNLHFSPQLSSHNLHPPPLQTFFPLSLSPPPLPLLLPTFSSLFPFPLPPPPPHLSPPRSVSPLPLVPSPSLRPVLSLSLPSLPPPSYPSLPLPLSLHLPTSPLCFALSLPSPPSSPPPHSSVPRLANHNNYPGHNSVWLIAPLPSPCLIMICLQVAMIREGVYHPPSPLLLPTPPPPFFLWSPFPPPPSPFFIRGSLSHLLVPPPLFSWPPLPTPSPLFLLALSPLPPHSSSGFLSPHLLVPPPLPPGPLPPSSLPPPSSYGSSPHSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHA5</accession>
    <name>A0A3R7MHA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Na+ channel domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_024326</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000813">
        <property type="protein sequence ID" value="ROT82514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHA5"/>
    <dbReference type="STRING" id="6689.A0A3R7MHA5"/>
    <dbReference type="OrthoDB" id="6366127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF296">
        <property type="entry name" value="DEGENERIN-LIKE PROTEIN DEL-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 14" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="489"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT82514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="521" mass="57281" checksum="47E7C90F1273490F" modified="2019-04-10" version="1">MAENLEDLAPEEDLDDLKAMSSERRTVDIIGHVFRVTTNHGFGHAWSRGRTVKMTISSWLIPNCATTVVLLFGSAFLVLSPPGHEASSIAMCSRPHGFGHHDRQQVAHGQGDQAKVAWNENDEGLQLPSVAICNLGLLSKSRIEAMNIPVNVSNFIMGLVAGTLLYRPEVFVAEEGRAFLQESTRYVGDLMKERNLTLVQLVDALSLRCEDMIAYCEFGLNGGDTTLCCGFMTPIPTTLGQCYVSFAGERTRQIYRGAHSSFSLIFKDVTREYPGQVGSCRVKLGHVGSGRVKLGHVGQVGSDIDTRIIDPMRKAKQGLQISLFSNLTHPGLFVAGGGTVIPPGTHTDLEVSLFEPLLDWREKPCAPADSFDFHKDPRAFLFTSVNCEFAARGEAVRQYCGECNMYFNAVSVGAQRKCVWICQQYDFQHTAVTTRIPAGLEAKISQQLGLPEGEKLSVVTIFYPRLLYHLNTLTRMSISEMISELGGEMGLFLGSSLISLLEVVVFVVLALCAFWGKLRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJZ1</accession>
    <name>A0A3R7MJZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000502">
        <property type="protein sequence ID" value="ROT84760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJZ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="206" mass="23253" checksum="D0AA27D0AADFD9EC" modified="2019-04-10" version="1">MNSRFVLVVIVPIFLRNNRLILLHGNTLISFLEPKASRGFTQRRQHRLYKQREPRGDFSVQATSLACCVTRSSFSLSQKMRVVAAFVWAVAGAWALEEGGVGSLYDQHFPPLHPNCTQSLTDLLLRQESQLRESAGILKEILSETKGSLATEASCSGTFLKFGGTCLYLAKDVKKLGMLLGPSARTWERLGRVPRRQRTRRGYWIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK39</accession>
    <name>A0A3R7MK39_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000630">
        <property type="protein sequence ID" value="ROT83877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK39"/>
    <dbReference type="OrthoDB" id="8963674at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="393" mass="45001" checksum="6261584B42EDB350" modified="2019-04-10" version="1">MGGRVGWGSRGEYGEVDESEGRRRTVPREPVPQRTSTPENQLPRETQYLREPSYPPENQYLREPVPQRNLPREPVPQRTSTPEPVTSEKPVPQRTSTLREPVPQRTSTSANQYPENQYPREPVPQRTSTPENQYLRQPVPQRTSTRENQYLREPVTPQRTRRTSTSETSTSENQYPENQYLRNQYPSEPVPQYPSEPVPQRNQYPQRNQYPSEPVPPTEPEYPQRTSTSEKPVPQSSTSSSWHRGSFGYREPPVSVESPWEREPVPQRTSTSENQYLSEPVPPENQYLREPVPQSSTSSSWHRGSFGYREPPGSVESPGRENQYLREPVPQRTSTSENQRTSTSENPPQRTSYLREPVPHRTSTSRAAHGTGVLLGTVSPPVRSSPLGEREPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNN4</accession>
    <name>A0A3R7MNN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transducin beta-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024951</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000907">
        <property type="protein sequence ID" value="ROT81892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNN4"/>
    <dbReference type="STRING" id="6689.A0A3R7MNN4"/>
    <dbReference type="OrthoDB" id="206335at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042410">
        <property type="entry name" value="WBSCR13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44321">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44321:SF1">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="279"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="49991" checksum="A9E8E069078DFD4A" modified="2019-04-10" version="1">MMAGEETDVSSAPTMLFLSIVIGATILVLAWLIRLSRSQTNNTAEKPSKPKRKEPQVTKKPPPPKKQAKITKKAVVTQYTHQELITTLKGHTGSITGGSFSSDGKHFITAADDRTVLIWNADQFTQRENKSVRGNIEFDYATHIRWMPNSKGFTIFKKMENAISIYKVSKTSSGMIGNVQEFSNFPKQGDEVADIITFDVAVTGNIIMTCNSKNQLVIWNFKGEVLEQFDTRHGDTYSATLSPCGRFIATTGFTPDAKVWRLKFGASESFEGVKRAFDLTGHKASIYSCSMNADCTRMVTVSKDGTWKLFDTDIEFEKGQRPYELLTVPYDGMDHKVMIRMSPDGRTVLLAVQADLIFYSAITGEKLNVINDIYGGDIIDVMFDPTSKQVVTLGDRHARVFQNVAGYIAAVQDLEQCLKKSTNSAMSERIKKQIKEAKAALAVVKKSIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSU9</accession>
    <name>A0A3R7MSU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative heparan sulfate 2-O-sulfotransferase pipe</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021453</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfotransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000450">
        <property type="protein sequence ID" value="ROT85050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSU9"/>
    <dbReference type="OrthoDB" id="10019582at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007734">
        <property type="entry name" value="Heparan_SO4_2-O-STrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12129:SF20">
        <property type="entry name" value="HEPARAN SULFATE 2-O-SULFOTRANSFERASE PIPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="27226" checksum="65A243DF55756B77" modified="2019-04-10" version="1">MLPALPVVPPLTSLSLPRVSDLVAAVCIPASCLPPPDAAVPDQTAPPTGPEEPLSLVERGAPAVASSFAVPPPVNVTGAAREDLLLMTPILKCGATAMRNLLKVLKNENKFDLVISQPKKAELVHIPQMKLQHDPLTLDLALVPSATWGQRVVLLAPTALMQSFAYINFTSHHFRKPIHISLVRAPVERAISWFYHARAPFQLVERHNRFPDTKFPTRKFLKKVGTATGQSRRRLSFSEAASTRHGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MU65</accession>
    <name>A0A3R7MU65_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_011966</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002517">
        <property type="protein sequence ID" value="ROT69805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MU65"/>
    <dbReference type="STRING" id="6689.A0A3R7MU65"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000173">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12 13" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="42"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="15">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT69805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="143" mass="15659" checksum="5A1E839315E3FB44" modified="2019-04-10" version="1">MIFPFIVHHQRQPRLAKESVGHAIGSIPGHPALPHVPMRPAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MYB7</accession>
    <name>A0A3R7MYB7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell surface glycoprotein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MYB7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="769"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="817"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="916"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1227"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1423"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1592"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1692"/>
            <end position="1894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1922"/>
            <end position="2002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="393"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="396"/>
            <end position="413"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="507"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="536"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="619"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="682"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        <location>
            <begin position="959"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1114"/>
            <end position="1147"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1213"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1281"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1340"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1435"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1494"/>
        </location>
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        <location>
            <begin position="1495"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1529"/>
            <end position="1541"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1542"/>
            <end position="1553"/>
        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="1573"/>
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        <location>
            <begin position="1592"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="1858"/>
            <end position="1894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1922"/>
            <end position="1946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1959"/>
            <end position="1968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1993"/>
            <end position="2002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2002" mass="229802" checksum="6C98984F55AB55AE" modified="2019-04-10" version="1">MQSQRRDQQCHQRRQNLRSQQREQQCHQRQLNLQSQQREQSAPTTEPAISTERTTVPPTTTEPAISKREQQCHQRQLNLQSQQREQSATTTTEPAISTERTKVPPTRHEPAISTERRTVPLTTPEHAISTERVPPTTPEPAISTERQQCHQRQLNCQQREQKCHQRQQNLQSQQRDNSATNDARTCDLNRENNKRTTVPPTTTEPAISTERTTVPPTTPEPAISTERTTVPTTTTEPAISTERQQCHQRRQNLQSQQREQQRHQRQLNLQSQQREQQCHQRQLNLQSQQREQQCHQRQLNLQSQQREQQCHQRQLNLQSQQREQQCHQRRQNLQSQQRENSATNEPAISTRATVPPTTPELRSQQREQQCHQRQLNLQSQQRENSAPTTTEPAISTERTTAPPTTTELQSQQREQQRHQRQLNLQSQQREQHATNDLNLQSQQREQQCHQRRQNLQSQQREQQCHQRQLNLQSQQREEQCHQRTPAISTERTTVPQRRQNLQSQQREQQCHQRQEPAISTERTTVPPTTPEPAISTEKQQCTNDNRTCNLNRENNSATTTTEPAISTERTTVPPTTPEPAIQQREQQCHQRRTCNLNRENNSATNDARTCNPTERTTVPQRPEPAISTERTTVPPTTPEPAISTERTTVPPTTPEPAISTERTTVHQRRQNLQSQQRETTVPPTEPAISTERTTVPPTTTEPAISTERTTVPPTTPEPAISTERTTVPPRQNLQSQQREQQCHQRRQNLQSQQREQQCHQRQLNLQSQQREQQCHQRRQNLQSQQREQTVPPTTPQLQSQQREQQCHQRRQNLQSQQREQQCHQRRQNLQSQQREQQCHQRRTCNLNRENNSATNDARTCNLNRKNNSATNDVRTCNLNRENNSAINDARICNLNRENNSATNDARTCNLNRENNSATKSVRTAISTERTTVPPTTPQPAISTERTTVPPTTPEPAISTERTTVPPTTSEPAISTERTTVPPTTPESAISTERTTVPPTTPEPAISTERTTVPPKQNLQSQQRENSATKRQNLQSQQREQQCHQRRQNLQSQKKEQQCHQRRQNLQSQQREQQCQNLQSQQREQQCHQRRQNLQSQPPCNLNRENNSATNDARTCNLNRENNTCNLNRENNSATNNTTTCNLNRENNSATNDDRTCNLNRENNSAINDDRTCNLNRENNSATNDDRTCNLNRENKKNNSATNNARTCNLNRENNSATNDARTCNLNRENNSATNEEPAISTERTTVPPTTPEPAISTERTTVPPTTPEPAISTEEQHSEHNSATNDARTCNLNRENNSATNDARTCNLNRKNNSAPTTPEPAISTERTTVPELQSHRENNSATNDARTCNLNRENNSATKRRQNLQSQQRECECATNDARTCNLNREKCHNNARTCNLNRENNSATNNARTCNLNRENKQCHQRRQNLQSQQPQRPEEQREQQCHQRRQNLQSQQREQECPTNTNLQSHRKTNSATNDARTCNLNRENNSAINVQSQQREQQCHQQRQNLQSQQREQQLPNDPEPAISTERTTVPPTTPETCNLNRENNSATNDAEPAISTERTTVPPTTPETCNLNRTTVTRICNLNRENNSATNDARTANLNRENNSQRRQNLQPVRTCNLNRRNNSATTTPELQQREQQCHQRRQNLQSNRENNSATNDARTCNLNRENNSAINDARICNLNRENNSATTQNLQSQQREQQCHQRAKPAISTEENNSATNDARTCNLNRKNNSATKRRQNLQSQQREQQCHNDARTCNLNRENNSQPTTPEPAISTERTTRTTVPNPEPVNRENNSATNDARTCNLNRENNSAPTTPEPAISTEETTVPPTTPEPEILTERTTREQQCHQPPAAISTTTNLNGENNSATNDDKTCNLNRKNNSATNDTRTYNLNQRRRTCNLNRENSATDDARTCNLNRENNRATNDGRTCNLNRDNSATNDARTCDLNRDNSATDDPRTNKADRQNTPTDRSGTDKFSRGTDSSDNGSRTRHLVKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MZD1</accession>
    <name>A0A3R7MZD1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beclin 1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Putative beclin-1-like protein isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008281</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2018-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Wang W."/>
                <person name="Zhuang K."/>
                <person name="Zhang Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <dbReference type="EMBL" id="MH797016">
        <property type="protein sequence ID" value="QBZ67168.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01002043">
        <property type="protein sequence ID" value="ROT73282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MZD1"/>
    <dbReference type="STRING" id="6689.A0A3R7MZD1"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.40:FF:000001">
        <property type="entry name" value="beclin-1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="5">
        <location>
            <begin position="105"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="4">
        <location>
            <begin position="234"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="147"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QBZ67168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="47997" checksum="F7B507945CDF16C7" modified="2019-04-10" version="1">MDARVTVNFVCQRCLHPIQLDPGFSHLNEHILAELALPIFPGEEAEFDASEVDKLVPPLQLTDSGHHPHGFTLVGESGDTEKSQPLKVATGLYDLVSSNSDIDHPLCEECTDALLDLMDTTLSRTQRQAQMSQQLLNSLADMPDMDVTALESELKNLQAEEERLLAELSEVEAEQKAAREVLEKHEEEKARLEDEEERYWREYCTHKSQLTAMEDENRSLKSQLSYTQNQLEKLKKTNVFNTTFHIWHSGHFGTINNLRLGRLPTAPVTWPEINAAWGQTVLLLASLARKIGLKFSKHRLVPYGNHSYIEVVGESRELPLYGSGGFRFLWDTKFDAGMVAFLECVAEFQQHVEAQGGQAARFCLPYRINKHFIEDPSSGNSFSIKMQFNSEEQWTKALKFLLTNLKWGLTWVSSALFSSTQGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N438</accession>
    <name>A0A3R7N438_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001611">
        <property type="protein sequence ID" value="ROT76762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N438"/>
    <dbReference type="STRING" id="6689.A0A3R7N438"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="255" mass="26745" checksum="8CF799A7CFA27240" modified="2019-04-10" version="1">MSGPVPFLGSKISLISKSEIRYEGILYTIDAQESIIALAKVRSFGTEDRPTEMPVAARDEVYEYIIFRGTDIKKIEVCDTPKQPTLPGGLHNDPAIVQHSAPAVPSSFQAAPFSRQSLGPIGGGLGLSYGAYGQSMTQQGLPGTGGFPMGSTSQPSELSTVAGGGGGGGVGSLDQQPNTTPGAVPAPIGAPPQSGTHALHQTDILVGSRSSTPTARKSPVSDAGVQVSPPPSREEKKKSPQQQRQSQQERYFYWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N498</accession>
    <name>A0A3R7N498_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative tetratricopeptide repeat protein 33-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001595">
        <property type="protein sequence ID" value="ROT76903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N498"/>
    <dbReference type="STRING" id="6689.A0A3R7N498"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052658">
        <property type="entry name" value="TPR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15544">
        <property type="entry name" value="OSMOSIS RESPONSIVE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15544:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="244" mass="27638" checksum="E7853F408CBFEFE7" modified="2019-04-10" version="1">MQSFGWKRKAGLTKPKPAVFSQDNVEVDNDMNDPDVDWLTATKKPKVLQLEDAKAKARRLSNEGVMLAESERWWAAIGRWNAALALTPDDYALHEMLAQAYMQVGEVFPALRSAEAAVQLYPNWWVGLQTLGRAQLGLGDVAMAVKTFSKAVHIRPDEQELWREDLQWAVGLLKKYKEIEAEKEKMKDGATITEPSIEGTVRERSIQIYDRQRRKEALLKGNPEGNLDNGSVIDVTKMVRMRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N671</accession>
    <name>A0A3R7N671_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative serine/arginine repetitive matrix protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001400">
        <property type="protein sequence ID" value="ROT78309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N671"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="43843" checksum="0FD84ECDF536E266" modified="2019-04-10" version="1">MLPSGRERRTNRIMSIRFTTSLPLHCPFTPLHCHFTTKLQLHWHFTDSLHYHFTALHFTSPLHYTSLHTHYTSLPLHYHFTATSLPLHCHFTFTATSLPLHYHFTATSLPLHCHFTTLHFHFTATLSLLHCHYCTSLPLQLHFTSLYYHFTALPLHCHFTTTSLPLHSTSLPLHYHFTATSLPLHCHFTATSLPLHYFTTTSLPLHCHFTTFTATSLPLYTSLPLHCHFTTLTATSLPLSLHCHFTATSLPLHCHFTTTSLPLHFHFTALHYHYCHFTATYYHFTTATLFNCHLPLHCHFTTTSLPLHCHFNCHFAYTSLPLHLPLHYHFTATSLPLHCTSLPLRLHFDATSLPLHCHFTATSLSLHYHFAYTSLPLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NL12</accession>
    <name>A0A3R7NL12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004380">
        <property type="protein sequence ID" value="ROT61079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NL12"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="623"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="687" mass="75182" checksum="669A06669754D25D" modified="2019-04-10" version="1">MLLRSRRSAEFRSGSERFQFYIHRESRRRRPPGTHGSYHPQLSAEHALLPNAKSLTTTDRSTPPTSFPPPQCLPSFTFVPPSPSPFTLHIATHVFFLPSSSVLPSPASSSLHRPTPTSSSCLPLVPRSPLPFPPIILPHLSSCYLVYVPRLSAPPLSRQTYPNSRPSSVLSTPLDPSLQSLTQRPFVYLRPRPPSALPPISFLPTHLLFTSSTSPPPIPFRAPSIPNCLLLLPRLTSSLPFPQPYRPTSSSTCARPPSPRSPLPPIPDSLTSSSYYRSSTVSPRLLTTPVPSPPYRPWITAPPCLKYSHEPCHSQGPSVKRSALPPLSLLPPRLTLSSPSLLRPSPPSPSSPSLPPPLPFFSLATWTSPPSSPHCTFPSSADFRPLPPSRLLPRVLPLSLSLRRRPPLPPLSHVLPSLFSTLSPVHFPDFSAPPPPAPLLPSTTTPFFPSLRSPCRDFAPPPSPIFRLSTPLPDSRPSRPLSPLPSLLGMTSPSPTSPSPSSSLLPSLNPSSHFSYTHLFHFACFGSPPPTTTSYSQLKVIPVPFNRSLFLNILSFHFSALFSFFHLYLLLHFSPLLLLKPPFTSSPLLYFSSLLPFNSLLSLHFSPLLLLAPLSLHPSSPFISLLFSLLHISPLFFISLLFSLSISLFFLPPLLSPFHLSPSPLLSLHFSPLLPLLPLSLSPSPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRU5</accession>
    <name>A0A3R7NRU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003152">
        <property type="protein sequence ID" value="ROT65036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRU5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="476" mass="50301" checksum="0C0995A4373560D3" modified="2019-04-10" version="1">MYPNTPLIIVPPHPTPPPPPTHHPHTPPHHFSNTPLPSQQTPASPIPHTPPLLHTPSPPPQTPPSPPPIPSLPPIQTPHTTRTSPLPQTPPSHSHNPLPSLPQTTHPSPTYPFPPPHPSPPPAPPGHKPPPSLTQTPLSLHQTPPLSPTYPPFLPTNPSPPSHKPLLRPTTPPPLPPTNLLPPLPPTPQPSPSLPPTNPSPPLRPTTPSPPSHKPLTPLVPQPLPPPPPHPPSHNPSPPLPKPLPLPQPLPSPPPLPHKPLTPLRPTTPSLSLPQTPPLPSHKPLTPSLPTPFPPSNPSLRPLTPPLHPPNPPNPSPTPPPPSHNPSSPPTNPPPLPSVPQPSPSLQPPNPSQHTPPPSHKPPPLRPQTSPLPPQTPPLSPTNPFPLPPTIPPLTPPPSHKPPLPKTPHPPLRPTKPPNPSHIPLPPLPSHNPSPPSQPLTPPPPTYPSPPSHKPLPSPQTLPHTPPSPSHLPTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P540</accession>
    <name>A0A3R7P540_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001747">
        <property type="protein sequence ID" value="ROT75664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P540"/>
    <dbReference type="STRING" id="6689.A0A3R7P540"/>
    <dbReference type="OrthoDB" id="434324at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09510">
        <property type="entry name" value="SAM_aveugle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039144">
        <property type="entry name" value="Aveugle-like_SAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052268">
        <property type="entry name" value="SAM_domain-containing_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20843:SF0">
        <property type="entry name" value="PROTEIN AVEUGLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20843">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="2">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12765" checksum="C42D4A3649AA3D92" modified="2019-04-10" version="1">MTMTLGVDASQTAKPKGKLTRPKPCYLWTTADVQKWFKRHCSEYFQLYSHLLIQHDITGKALVRMTEGTLIRLGIAHPEHLEAIWREILKLRLKADIQEMKEIEMSSIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9D4</accession>
    <name>A0A3R7P9D4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gamma-interferon-inducible lysosomal thiol reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002108</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GILT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001282">
        <property type="protein sequence ID" value="ROT79159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9D4"/>
    <dbReference type="OrthoDB" id="958254at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004911">
        <property type="entry name" value="Interferon-induced_GILT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234">
        <property type="entry name" value="GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13234:SF71">
        <property type="entry name" value="GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03227">
        <property type="entry name" value="GILT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="45873" checksum="9C19D462D35F4294" modified="2019-04-10" version="1">MEYEHCPTTCESDVEEDVLVLVEVPTGPDGRKRQIRHTRKSPYGWQYAWTMSLLSLVLTLVLINDMITYGRFESRWQREEAALQLLQEARAHPGGRQEVAVRPTMRIEIYYEVLCPDSRNFIMKQLTPAYEKLKDILQVGLVPYGKAETQEKNGKVTFDCQHGPRECEGNIVHACVTNVIKDEAKQIAIVHCMIDRNEQPMVVGKKCVEKHGENWGKISSCVTSDKGTSILKHMGDMTHRLKPEVTFIPTITIDGSQDDQKNILKDFHKVDVTSARQTEARGRFWETYASCPSVLLLPLYALPSRLSLFLSFPSSFPSSSLPSLVCCFPPSLLLLPFLLPFPPCFASPSLSSFSSSPSPSLPFPFLPTSSAHFPSPSSLLFPSPFRFSSSLLPLPPLLLPHVHQLPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PI83</accession>
    <name>A0A3R7PI83_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002814">
        <property type="protein sequence ID" value="ROT67394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PI83"/>
    <dbReference type="OrthoDB" id="6343673at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="355" mass="39051" checksum="421E68BC94FD8017" modified="2019-04-10" version="1">MHPKSLISICIDNIVSATIIYSLSHPPEITWPGVSQLWATLWRLPLQIPLRASRLLHAHLTHDLCEATLPLMTLLAAEARKVSLCPTDRRLASARFSDKMLKFIRLESQHELRDLDITGVDLGLDTSLLESLLPRCPNLCALKLGGNTSPGVLRAARACPIQVLHVSERLVWNPRVTEKDLVEIFFGVTDVQADQMLQNIKDAKPLNLNLSWPLLKDLCTGFCRASSPDTPKLKLKSCTVVSGEFVRVAVAVPDLEELTLISRGGCDHSTAEDLKVLRTLPSFKVLRLRDLRHFGQGDLSIVLDSLKLIGPKLVELELQGGKVGEACVGAQGSEDNGKTTVANPRYLRSSTINTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJB3</accession>
    <name>A0A3R7PJB3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative LIM homeobox transcription factor 1-beta.1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_007890</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002007">
        <property type="protein sequence ID" value="ROT73681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJB3"/>
    <dbReference type="STRING" id="6689.A0A3R7PJB3"/>
    <dbReference type="OrthoDB" id="10068367at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000227">
        <property type="entry name" value="LIM homeobox transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000103">
        <property type="entry name" value="LIM homeobox transcription factor 1-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050453">
        <property type="entry name" value="LIM_Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208:SF166">
        <property type="entry name" value="LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24208">
        <property type="entry name" value="LIM/HOMEOBOX PROTEIN LHX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9 11" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 10" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="13">
        <location>
            <begin position="59"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="14">
        <location>
            <begin position="152"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="9">
        <location>
            <begin position="154"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="210"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT73681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="353" mass="39005" checksum="E553BF8A5FE30303" modified="2019-04-10" version="1">MALPPRASLGGGARLQQHLKPSPPDAAPASSPWSRESPGRDLLAMTDASPVFPSRLFSVKCAGCGDRLLPHELVMRAQSLVFHLHCFACVVCCQVLQKGDQYVLRGHQLFCRADYEKEMFLLQQHGPQSEWLSPLGDDFIVDDGSRPRDGRRGPKRPRTILTSAQRKQFMASFSVSPKPCRKVREQLAKETGLSVRVVQVWFQNQRAKMKKLQRRAKQSEQNNNDKDDKDEKGENGKKDGGSEGQYGGLTPIDSLDSPYATTPKSSAVPYSPEGESFPAHSGDSFCGSDISFEEGRMDQFDDQGEMSSGPPPPPQQPQAPPDVPAMVGVAGSMYPQINPIDKLYLMQNSYFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJJ8</accession>
    <name>A0A3R7PJJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001966">
        <property type="protein sequence ID" value="ROT73925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJJ8"/>
    <dbReference type="OrthoDB" id="7474354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="623" mass="67637" checksum="ADF14AE599D543CD" modified="2019-04-10" version="1">MYFSLPGSEATVLFSPWQRRCFSLRRRCDGTFLSLATVRSDDLLFSPWQRRSDGTFLSLAAFSPLATVFLSLAATVLFSPWQHGTAAGAFLSAATVLSLPGSDGTFSLPGSERAATVLFSSLAATVFLSWQRRYFSLPGSDGTFLSLVLFSPGSDGAATYFSLPGSGYFSLPGSDGTFLSLAADGTFLSLAATVLFSPWQRRCFSLPGSDGTFLSLAARRYFSLPAATVLSLPGSDGTFLSLAATVLFSPWQRRCFSLLAATVLFSPGSDGAFLSLAATVLFSPGSDGTFLSLQRRYFSLPGSDGTFLSLAATVLFLSLAATVLFSPWQRRYFSLPWQRRYFSLPGSDGTFLSLAATVAATVLFSPWQRRYGSDGTFLSWQRRVLFSPGSDGTFLSLAATVLFSPWYFSLWQRRYFSLPGSDGTFLSLAATVLLSLAATLSPPWPATVLFSPWQRRYFSLPGSDGTFSLPGLVLSLPGSDGTFLSLAATVLFLSLVATVLFSPWQRRYFSLPGSDGTFLSLAATVLFSPGATVLSLSATYFSPWQRRYFSLPGSDGTFLSLTFLSLQRRYFSSLAATVLFSPWQRRFSLSATVLSLWQRRYFSLPGSDGTFLSLSDGTFLSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLI8</accession>
    <name>A0A3R7PLI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PLI8"/>
    <dbReference type="OrthoDB" id="6355222at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="692" mass="75394" checksum="DDD82B0C4A62F382" modified="2019-04-10" version="1">MAIMIQKVKVEPGAFASFDSIPKNPYGYSEEVHREIYRSKGPGSGFERVELIPDNPYGYSTQIQNVKAGPGAFAAVDSIPKNPYGYSEEVHGDIYRSRGPVSGFEKVELIPDNPYGYSAQTQKVKAGPGAFAAVDSIPKNPYGYSEEVHGDIYRSRGPVSGFEKVELIPDNPYGYSAQTQKVKAGPGAFAAVDSIPKNPYGYSEEVHGDIYRSRGPVSGFEKVELIPDNPYGYSAQTQKVKAGPGAFAAVDSIPKNPYGYSERSSWRHLQKQGSKEVHGDIYRSRGPVSGFEKVELIPDNPYGYSAQTQKVKAGPGAFASVDSISKNPYGYSEVVEREIYRSKGPGSGFEKVDLIPNNPYGYSKKTEKGTAASEAFESVAAIAQNPYGFSEKVQGDIRTQRALSSGFENVKSIPTNPYGYSTEVKELKKSPSGFETISSIPKNPYGYSEQIQADNQRARSIGNGFVKVDAIPNNPYGYSTEIRNLKWFEGGFVKVDSIPVNPYGYSEQIQGDNFKMRSTGSGFEKVEAIPNNPYGYSTEAKKLQDQPSGFITVKSIPSNPYGYSEKIESSANHGKSLPTGFSEVKSIPSNPYGFSTEIKGLTNAPSGFEAVDAIPRNPYGYSGDIRSDVHTPKARTSGFVSIQSIPTNPYGYSEKVADLKSAPSGFEEVDFIPSILMDIQTEFNQNSTEPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PM59</accession>
    <name>A0A3R7PM59_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_010660</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01002350">
        <property type="protein sequence ID" value="ROT71034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PM59"/>
    <dbReference type="STRING" id="6689.A0A3R7PM59"/>
    <dbReference type="OrthoDB" id="6344558at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF63">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT71034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="58266" checksum="84657CC0B2F36D16" modified="2019-04-10" version="1">MKLIMLNRQWKIVFLAGVASLFVYVRVTDNGQVQEYKQGIRERVDYIMQNARLPSRGDVQVLLEALDDARRGFSGKQDTQGGMPETTLRSDTIIHQKSNASLDSEVTGRTSSSVPVSSVRKSNPTKEVVFPSVHDCNMTAYKEQIKNHKGPTIPTMNVYPCRSWHYPSRDTSWPIVVEPTKGKILESISLSHVEEEARELVEEGMEIQKARVARLADTCNSHPELFIRQYVSLVWDTSRSPPLVYCPIYKVASTTWMVYFQRLAHVNDDNHALDKYKKAGKERKKYMPRFGGGHRRVFEEYKAPSTSREKNQVFQSSLRFLVVRHPFTRLLSAYRDKIERPNPKPFAPYFEDLQRAIILKYRPPDSNITATTPTFPEFVDYIIDFTANLTTAQEWDENVVCWTPYWVQCGVCSSDYQVVIKLETMTEDEQFLAQIANLKEIQNVFEWRNHKKFSKSSKEVLPVYYKSLTKKQILLLYERFKIDFELFGYTVEEYLDYSDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMM3</accession>
    <name>A0A3R7PMM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative metalloreductase STEAP3 isoform X6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004491</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001595">
        <property type="protein sequence ID" value="ROT76906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMM3"/>
    <dbReference type="OrthoDB" id="550646at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008823">
        <property type="term" value="F:cupric reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052851">
        <property type="term" value="F:ferric-chelate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015677">
        <property type="term" value="P:copper ion import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051267">
        <property type="entry name" value="STEAP_metalloreductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14239">
        <property type="entry name" value="DUDULIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14239:SF0">
        <property type="entry name" value="F420-DEPENDENT NADP REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="415"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="480"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="529" mass="58340" checksum="C350B78E8733032F" modified="2019-04-10" version="1" fragment="single">RLKIAAITVTTLKEALEQGEVVLVAIPAEHHDSLPRHLLAGKIVVDVSNRSPDSPRRPESVAERLQECLPESHVVKAFNTLSAFALQQGDVRGSKEVPICSNSSRGRERVSALVKVLGFTPIDRGVLENARDVENIPFRFFPERQICPNIQNEEPWDWNRFIKLPLNNGMLAFALSGTVLLLMCYVPGMIAAYIQLSRGTKYSTFPSWLDRWLKARKQMAPCIPHLLLFQAFMSIFTLMATGMKQPLQWTQNLYLALGAVLTAVLAILGVATIPSVAATLTWREFDFLQRYLGWLSVVLVTLHALFKGNVFLLKNRFVCYVIPHETHPIISNRRRLFMQFDSIPETPDPTSSPNLSNLALCRSLSLACLPPPSLPLTTPSPPPRFPHPTPPHTSHSSIPPHIPYFTPPPPLSYAHPPLLSPHPSPQSLPLLTPLIPTPPPPSLPPSPQYPLSTLPPSPFLAPSPHSSTPPSPLLSLSSLPPFPPRSPPPPPPPLSFPFLPLLPSSPLPPLPLPPPHPLPRYSLMQLADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN01</accession>
    <name>A0A3R7PN01_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAD synthase</fullName>
            <ecNumber evidence="3">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_009954</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002259">
        <property type="protein sequence ID" value="ROT71711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PN01"/>
    <dbReference type="STRING" id="6689.A0A3R7PN01"/>
    <dbReference type="OrthoDB" id="270728at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23948">
        <property type="entry name" value="FAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="entry name" value="MoaB/Mog-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056596">
        <property type="entry name" value="FLAD1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24102">
        <property type="entry name" value="FLAD1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="Molybdenum cofactor biosynthesis proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoaB/Mog" evidence="14">
        <location>
            <begin position="75"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT71711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="62700" checksum="77D1A3C4CCE211A5" modified="2019-04-10" version="1">MNLISQVLWQGGRWGAAIKSVNPARRTVTPAVNTLGRRRSYRASFPGVHRGLHTTFVRMSEQNGIPEASSVPTAGIIIIGDEILKGQTRDTNTHFLSKHLHSYGVKVQRVSVIPDDVPTIAKEVAQFSKAYTFVLTSGGIGPTHDDLTFEGVAAAFEEKVHPHPLLVKLISGFFKTDDLSSPAMKMAHIPESAELHFGEDKSKGVKSRYPIISVKNVTIFPGVPHLLERAFALLGEKLFHRPGMGFKVHRVFLTADEVSIATYLNDTVAKYPSVSFGSYPKLFHSYYKTKITMESLDEEILQEAEQYFKSQLEEGTVIDYMEDTVTSPWDYIDNLSVLNPSLEAPLQEALDILNQCFDRYSPEEICICYNGGKDCLVVLHLAYALMQKKYPKNKLQAVYITEPKAFPQVTEFVQHSVNRYDLDCDIIPGPMKAALAKVLENRPKIKAMIMGTRRSDPYSDELDFFSPTDKDWPAMMRVNPILNWKYSNVWDFIRGLYLPYCPLYDRGYTSLGSQDNTLPNPLLETRDRIGQVVYLPAYTLKEEDMERKGRISSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSQ8</accession>
    <name>A0A3R7PSQ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000967">
        <property type="protein sequence ID" value="ROT81478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PSQ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1769"/>
            <end position="1796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2011" mass="213911" checksum="96AE06B147285194" modified="2019-04-10" version="1">MAIQPPNHLSHCHLHPAPHPATLPPQHLSLPILPSHLTLYPATPTISPIAIPATSATSPCYSYTATSLLASCTRPQSCYSTTTISPCHPAPPSHPPGYLPPPNHLSIAHLPPQPLHPPHLLFYTNHLSIAILPPSHYPATTPNISPCHPATTQPPTLLFYHPNHLPCHPATSTLLLLTKPSLHCHPATPATSTLLFYPPQTILHCHPATPATSPCYSTTQLISPCLLPPHPAIPSHPNHLPPCHPATHPAILPPQPSLHSILPPHPHPAILPRQPSLHCHPATPATSPSILPPNHFHAILHHQPPLYFYPAQPSPIASCHPPPHLLFSTPTISAMHPATPAPCYSTTPPSLHPLPPALTLLFYQPPTIFSLPSCHPSPHHPATLTTPNLLHAILPPQPPHLLPCHPNPLSMPSCHPSHLTCYPPPQPSLHCHPATQPPHLLFYHPNHLSMPSCHPSHLTCLFYHPTISPCHPATPATSPCYPATPTMPSCHPSHLTLLATSLHCHPATPATSPAIHHPNHLSIAILPPQPPHLLPCHPTISPLPSCHPSHLTLLPAAPQPSLHAILPPPCYSNTPNHLSMPSCHPSHLTLLFYHPNHLSIAILPPQPPHLLFYHPNHLSIAILPPQPPHPASHPNHLSIAILPPNPCYSTTPTISPCHPCTQPPHPAILPPQPSLHCHPATPATSPCYPATPTISPLPSCHPSHLTLLPCTPTISPLPSCHPSHLTLLFSTPTISPLPSCHPSHLTLLFYHPTISPCHPATHPATPTISPLPSCHRHSPCYSTTPTISPLPSCHSCYPATAPLPSCHPSHLTLLFTTPTISPCHPATPATSPCYSATPNHLSIAILPPQPTSPCYSATPTTIAILHPSHLTLLPCHPNHLSIAILPPQPPHPATLPPQPSLHAILPPTLTILNHPTISPLPSCHPSHLTLLPTPQPSLHAILHPSHLTCSCHPNHLSIAILPPSHLTLLPCHPTISPCHPATSPCYSTPTIFHCHPATPATSPCYPATPTISPCHPATSPCYSTTQPSLMPSATQPPHPACHPNHLPLPSCHPATSPCYPATQPSLHAILPPQPPHPATLPPQPSLHAILHPALTCYPATPTISPCHPATPPHPAILPPQPSLHCHPATPATSPCYSTTPTISPCHPATPATSPCYSTTPTISPCHPATQPPHLLPCHPTISPCHPATPATSPCLHPNHLSIAILPPQPPHLLSCQPSLHCHPATPPPHPAISPCHPATSPCYSTTPTSSMPSCHPSHLTLLFTTPTISPLPSCHPATSPCYSTTPTISPLPSCHPSHSPCYLPPQPSLHCHPATSPCYSTTPTISPFAILPPQPPHPAFYHTPTISPCHPATPATSPCYPATPTISPCHPATPATSPCYSTTPTISPLPSCHPSHLTLLFYHPNHLSIAIPATPATSSCYSTTPTISPCHPATPPCYSTTPTISPLPSCHPSHLILLFYHPNHLSIAILPLQPPHPATLPPKSLHCHPATPATYPAIPPNHLSMPSCHLTLLILPPQPSLIAILLPAPATHLTLLPWPPQPSLHCHPATPATSPCYPATPTISPCHPAILPPTSPCYSTTQPSLHAILPPQPTSPCYLCHPNHLSIAILPPQPPHPATLPPQTISPCHPATSPCYSTTPTISPLPSCHPSHLTLLPCHPNHLSMPSCHHLTLLFYHPNHLLHAILPPQPPHPATCHPNHLSMPSCTQPPHPATLPLPCHPSCYLPPNHLSPLPSSHLLLPTISPLPSCHPSHLTPATLPPTISPLPSCHPSTSPATLPPQPSLHSIPATPPPHPAPCHPATHHLHPATISPCHPATHPAMPSCHPATSPCYPATPTISPCHPATSPCYSTTPTISPWPSCHPSHLTLLPCHPNHLSLPSCHPSHLTLLPCHPNHLSIAILPPQPPHPATLPPQPSLHCHPATPATSPCYPATPTISPLPSCHPSHLTLLPCHPNHLSIAILPPQPPAIPTSCCYPPCHTMPPAPYPFEPPCLVLPWLRFSFLVLRFLREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWA7</accession>
    <name>A0A3R7PWA7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_002202</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001294">
        <property type="protein sequence ID" value="ROT79074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWA7"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40237">
        <property type="entry name" value="LD44813P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40237:SF1">
        <property type="entry name" value="LD44813P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="1 3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="5">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="232"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="37709" checksum="502DF1465CCAE07A" modified="2019-04-10" version="1">MGILETELAELQQCVPRVIADSTVEACVPAMVRVNIERTKYKQIVACFQFQPDYPSSLALIELKSRHVSEKLLDGLVKLCEEEAKKYLGKPQVLHVLRFVRNFIDENPLCCCSEEISNVRKKLIAGSDELKLRQKTSSVVVKVQEGQYVMKYNITVPENYPDKQVGIEEKECNFPSVFRRWFLAQATEIARQCVEPPAKKRPKDPPFVLRPSMEPVVSFLVSEVHLYPKLECKMCRKKAFPTNPKDIETSESGPLHVERIYCGHVYHNKCLDKYIRTPPFQGGKKCHTCNNKIYHDKWKLTPETAEARWAHKQAKQRELDEVVDFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWD9</accession>
    <name>A0A3R7PWD9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Calcium-activated potassium channel transcript variant 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_022022</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000498">
        <property type="protein sequence ID" value="ROT84792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWD9"/>
    <dbReference type="OrthoDB" id="10035564at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060072">
        <property type="term" value="F:large conductance calcium-activated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048735">
        <property type="entry name" value="Slowpoke-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF33">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21014">
        <property type="entry name" value="Slowpoke_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="11">
        <location>
            <begin position="5"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT84792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="356" mass="38859" checksum="08B529080C147075" modified="2019-04-10" version="1">MTVLNGHVVVCLFADPDSPLIGLRNLVMPLRASNFHYHELKHVVIVGSVDYIRREWKMLQNLPKISVLNGSPLSRADLRAVNVNLCDMCVILSAKVPSNDDPTLADKEAILASLNIKAMTFDDTIGVLNQNPSTGGDTLSPLGSPIVLQRRGSVYGANVPMITELINDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSTTYFNQNALTLIRSLITGGATPELELILAEGAGLRGGYSTPETLANRDRCQVGQISLYDGPLGQFGESGIYGDLFCAALRNYGMLCIGLYRFRDTSSSCDASSKRYVITNPPDDFKLLPTDQVFVLMQFDPGLEYKPNRGDMAKDDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWT8</accession>
    <name>A0A3R7PWT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/glucose cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003902">
        <property type="protein sequence ID" value="ROT61962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWT8"/>
    <dbReference type="STRING" id="6689.A0A3R7PWT8"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005412">
        <property type="term" value="F:D-glucose:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819:SF195">
        <property type="entry name" value="SODIUM_GLUCOSE COTRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="562"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="591"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="639"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="706" mass="76986" checksum="990FAF1BB6DA679F" modified="2019-04-10" version="1">MMDNEEETTVLQWPDVLVIVSYFLIVLAVGVWASRRSERSTTSGYFLASRNMSWVPVGASIFASNIGSGHFIGLAGAGAASGIAVGGYEQGASYLLVALGWVFVPVYLSSGVYTMPEYLKQRFGGERISVYISCLSLALAVFTKISADLYAGALFMQMSLNKSSEEWLYISILILLGIAALFTMAGGLTAVVWTDLVQTVLMVLGALVLMVKAFSEVGGYEGLVDSYPYATASERARNRLNESCGEPPSDFMHLLRTVEPGKSNYPWIGMTLGLGILELWYWCMDQVMVQRTLASKNIVHAKGGCLLAAYLKFLPMFLIVFPGMAARVLYPNRVACASPEACTRICGSARGCFNIAYIELVLNLLPVVNPLLHISSSTSYYSALPCSSSHSLTPNFILPAHFILPALPCSSSHSTPTSYLPALPVPSHSPTPTSYLPRPPLSSHPPTPTSYLPALPCSSSHALTPPLPKGVRGLMLAVMMAALMSSLTSVFNSASTIFTMDVWLHLRRMCRRRGREGSLLSAPPSDVELVVVARIFVTAMVGVSVVWIPVIRNNATSELFDYINTINSFLAPPICAVYLSALFWNRTTEAGAFWGLMFGLAVGVFRFALEFTYTPPPCGLDADYVEPAIITALLTRLHYLHFCCLLFFLTILVIFCVSLTTPPRPKDCRREVKMMKCSKGKVNPLLKMNPVHMQAASEYLNDTSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4W2</accession>
    <name>A0A3R7Q4W2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative Peptidyl-prolyl cis-trans isomerase B2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_013202</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002649">
        <property type="protein sequence ID" value="ROT68654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4W2"/>
    <dbReference type="STRING" id="6689.A0A3R7Q4W2"/>
    <dbReference type="OrthoDB" id="252722at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051435">
        <property type="entry name" value="RING_finger_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22791:SF6">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="3"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="356"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="119"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT68654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="511" mass="56242" checksum="E2972A901A48FD29" modified="2019-04-10" version="1">MECKVCFNDYDQADRRPRVLPCGHFFCSICVTSLLKEGTLKCPICCSQHTIPDIMQIPIAYDFEELLSSINLASPGKREVPEPQQDIGIDPTRLRLIQLAVSSATSDCTQMQTQLRTYNTTLDNLITEHEEQVKNLTDMIQRHMNAQELLKKEKSRLTDLQGQGEQQYHLLQEAAESLHTSDKMDTDRAISSAEQCHAVTLMWIKQCNDTLPDVNAIQQSAKLRYATKKTIEVMNQEVDAGVQDAGVTASNRLVSGTLHATVLEKVNNIIGIPVETVTIESLRGLSMPVRMLVEAGKLAAVLTKQGKSRHGRITVHDGAICLHHLQNECPKTTQHLHTLPFYDVVASTETLSSLVFLDLAWPGSSPGRVYIRIIRDTPMAKNFVLLCTGEHGPSYTNTHFFGVVCKGLPGERIVGGDYEYNDGNGGAAVIPGLSGSGDYNKHCSVGAVGGWVSDDSRAAQFTVTTKKSLFPYIDPRVFGKVEKGLEVAKAAAKYRNIKNVTVVDCGIVIPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q6K9</accession>
    <name>A0A3R7Q6K9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002508">
        <property type="protein sequence ID" value="ROT69875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q6K9"/>
    <dbReference type="OrthoDB" id="6348248at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="961" mass="103222" checksum="25827E8513651688" modified="2019-04-10" version="1">MADTVSTQCSQDDGEPGSALATAAPVVQATPGGSQALETQTSSKPPPKMSLEVPVVCITPPSPIPGDSQDKPAESSPEKPNRVDGDPLQYLSCEVPNVSTKHPAAAAKESSLGVVPDINLDPLKHKQESTVLGGSEESRKEHEEQINVQIKSPLDNCPANHPLTDAERSVEKSDTRVEISTEKAASFESVSDSVTTCNESSTEKLTSESETSLKTSDEVGNATLENIPDSASLTEKNNTDHGAELSEDNTKNISPSSKDQTTPLTSSSSSVTEENVKEVVSSSSQEQVQAPVSENRASKVPLVLTDRSSSLPTVFSDQQSSKVPSAANQSSGSPLSCPSALADTLQSASSKEESNSSAVSDCSVSKNAHSSRTVQNSSSECGVEVEQSEVSSERSKEKTTDSISVTENLKEPLESEDVAKASKLTIKKVDEINDDHEVNTVDTTKVLSEQNVAHEVPVETIPVIVNTEEREQVKIGREVQGNFVSPVIPSSHSSAIASPDNVSSVDAEQLQPVTIGSSLQPLEEVQEASVSGDPSFAAADLALIDSSADEADSIGGLVINSVIGAADGVADFHPDEMETDRELTDISASAPHTVGENCDNVDSSDEIEPSAKRMRFENGGDDIEDKLQTSRNVNIKVSPIKNGHGLWDACKLRQILLEKGTIMLRLHASVDHMEMNDSDKENKDVDFTGIMIEIKDDDQDHILGLASLEPDADLCDPLAIGLTHNLDHTSPPHYSRGYPHHPRGRSTTLQPAMTRPVFKHLQSPPHSQHYMKQDLLGHPQPLEFEEPQLGTTEWAGKEYYGGLLLQRKAFPPSQYPGMSPAPPPPPRGRKRGRPPLSSRRGHCPPGGFPRSSPSKSRAYGKRHPEPIKYRPPTPPHHLLVSTLLKLNKSHYMANKAESKKVMKHLENLKHDILPGDGKKLSSTGSFEPTHGGDCLILVTQNGTGSKEGEECRSCDKNEEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QH43</accession>
    <name>A0A3R7QH43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative breast cancer type 1 susceptibility protein-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_002611</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001347">
        <property type="protein sequence ID" value="ROT78680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QH43"/>
    <dbReference type="OrthoDB" id="2384350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070531">
        <property type="term" value="C:BRCA1-A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031436">
        <property type="term" value="C:BRCA1-BARD1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="BRCA1-associated"/>
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        <property type="entry name" value="BRCT_dom"/>
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        <property type="entry name" value="BRCT_dom_sf"/>
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    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
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        <property type="entry name" value="Znf_RING"/>
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        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
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    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13763:SF0">
        <property type="entry name" value="BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13763">
        <property type="entry name" value="BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ZF_RING_2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="21"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="12">
        <location>
            <begin position="2090"/>
            <end position="2153"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="12">
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            <begin position="2168"/>
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        </location>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="10">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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            <begin position="722"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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    <feature type="region of interest" description="Disordered" evidence="10">
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            <begin position="680"/>
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            <begin position="730"/>
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            <dbReference type="ARBA" id="ARBA00022723"/>
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    <sequence length="2288" mass="251852" checksum="9646E7F09B05FA36" modified="2019-04-10" version="1">MEERLNQMSAVLQAMQKTLECNICLDLMNKPLTTKCGHSFCSECIHQVVKGPRSSAQCPLCMTNITRRSLGHNNKITNLVIAVRKIIASIKKDCCFEVTPSKYRPRPRPVISPEDDDSENEENDEPRRGTRKRGVTSHYNPEVHVPKPRAKSAKQRILATDNGQELSLHTDVRSDRFLKSEEGGTDQNRAVVDVISQEHSYSSPTKQEPVVRTSLIPTISRGRGGRGGVSLRGKSKMTSTSLKGKADAHMSGKPFGNGMKTGPSTYSTKKAEQQLEKNLLSVSQQDNGCIFPGEAMVSVQEDTDHLSKKLGRVEPADKVANWLTTSSEVGFRIGVTQSTDTLSTESEDNQLYQKAKDKGPSNSKLIEPKVNVMKKGNKKFIYPNEGTELSESKSATTTSSSQSVKKFFKLKVNEVVSSTLTESHLPIVKHDAKHDQSMLPQASSDDPYSFIPSQKTPKQLKTVEKRGQEVKSRARGMLKMSRGRVRGRGRGRGLIQAESSSTEPAGIFDESCVSTVDTTMLKQSTPLAKVNKMKQDIDISVIRPPDTVINFADNEPLPSVIVQTHADIEDDYGIPDSCPVNTKDEFDVLVSEAKDVCKTTPQGTQQIDGPEIDAEADLLFVTPAQGPDQPLDIITGKPKSAEDPSQQANTEAGCRTKKKRASDDSDSGNERSKRARVKKSSSSSGSDAESTQSSKKSKTKAEKAKEEVEALCSMFEEIEDHTLSTVSLVEAEKDNKKQEKEKEESMRSNISVFDKTLENTKLNRSIASTEGGKSAMPPPKAPVRNKKVKFHESLEENSAPSTSKDSLSSVATRSAGKKTIPRISHNARYASEMKLVEPSKNLAVSVSVKDTKSPGWSHVAGARKDLKTRHTSLNITGGEQRNINDSRTEGGTSVLSSKIAPSSEESEVSIDDQTQDYDVEHLCSSQSKKERVKKLKEIVSQLNKPEEESETVATHGNNVNSKETKPAIKESDSEKNKLGVQELNNKGSKSAVKEISGGEIKNLSTEVSSKNTKSADKEVRSKLIKSGTKDASDKESKSFGKKEDTYEDESTVKQIKSKENRCDTKLVLPPTACTTSIESKAAQKQGIDEKPKENSCHSSALLNPAETEPFECTEEPTRKSSVSSSSSDSTSNQVKGRLKRPTRAEQRNITSRLSRTSARQLNSSSSKLSRKTFSLSVNTQDLSTLHSDYEILSSLEDTEKPNCVPDPSGQKSVTSSNKVPEALKPKKSASTSSETSSVISKPRPPHHAMSSSTASDLLDNEKNKKDISPPATSLPTEATYSNQLVSEDSKVIPFRSVGPLCSKRCDEAGKGEAVALVGSTNRDLCLHAIPCEVYQVLMKYMTLLVTQQDNHSVCCGSSNLPKLLNSKEVQTSPMSEATEEKMHVEKKLQLKSSDSTSLVKPNSESDSQVIPNSCETQEMDIAIPLPASIGVKTKARKDAAADTETVVEAENDRSNLICLREEENKDTVTVKSALSSEISLDKNCLMPQKKKFDNASSSQNSDSQSSQMSTSLLAAPDVIETKHGRLTRSTNSSGDANSQAGEGRSVEKYDRGQHASQKVKERAGVGKTMVSKNNLVEVEKENLKNDSTLPVAISRPRRKPLQSGQPVIENIMSQLTKEEKRQVAEKIELSQIQNQSSHNIQKSLSTQNRPANSKPLFMSDESSHASRKQKDVLTVGSKNLEEEQEESDSDSPLKASLESKRQTFKRIRRPSSGSSSDDSDSDSVQPRKRKAKTISSSDSIQMSGRFKEGKSKENLEQHQLDSEEMRDLERLDKNVWEFFGHPDEDLLTNKDDDDKSSHVSIDDPSQKKDIIEFENDALVPSLPSDEDIPSTEDVMRNVQMDMDLVKKMRQQGQGDPEVISLISQEIQETAPSTQKPTFSASTKSLFNKVDKNLTKAEDLLCSGNSLFGGIVTPVDEPKSNSTKTTTVGNTKTKSNKEKAEMVDESDRDTEEDTENMSHSSAYSSQSEAISTQKREEVKDEVEMLKARVRELEAVVKKKETEESAKRNEDPEDDVLPPTCPTEISDTESEELFSSLPDLTACTQPKLPVSGFEKKTTKLSMSGPPMLVCTGLNSSELSKVQDLVNKLAPPGTKLMKSWVDGITHVVVKTDADRMAQRTLKYLYGVANGCWVVMLEWILDSITLKQLQNEEEYEVLDCTGVPGPHRARTTITPLFHGCEFYLIPPFMDVTLEQLQEMLEQCGARVVDSLQKFSQSKQSLKLIVLQTDGDHETDNIWKKHKKVCVAHDWIIECIGMYARICISPYIIGSPSQSHIAASNLPYALMQETQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QIW7</accession>
    <name>A0A3R7QIW7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Innexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">inx</name>
        <name evidence="13" type="ORF">C7M84_000935</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Structural component of the gap junctions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Gap junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Cell membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the pannexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001129">
        <property type="protein sequence ID" value="ROT80332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QIW7"/>
    <dbReference type="STRING" id="6689.A0A3R7QIW7"/>
    <dbReference type="OrthoDB" id="5867527at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005921">
        <property type="term" value="C:gap junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005243">
        <property type="term" value="F:gap junction channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000990">
        <property type="entry name" value="Innexin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893">
        <property type="entry name" value="INNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11893:SF38">
        <property type="entry name" value="INNEXIN INX7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00876">
        <property type="entry name" value="Innexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01262">
        <property type="entry name" value="INNEXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51013">
        <property type="entry name" value="PANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0965">Cell junction</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0303">Gap junction</keyword>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU010713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT80332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="177" mass="20422" checksum="5332C80866BB0AB7" modified="2019-04-10" version="1">MLKYVAAAKILKKHNAQVDNAVFHLHYRVTFVVFLISSALVTAREYIGNPIQCISKAVPGNVLNTFCFIMSTFSVPRHWDAPLGDGVAYPGVGSHDDEDEIKYHAYYQWVPFVLVLQAIMFYIPRYLWKNMEGGLFTTILAGLDKLTLDDSQRHKKHKILSQYMIKHLHMHMNWAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJB6</accession>
    <name>A0A3R7QJB6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000584</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001092">
        <property type="protein sequence ID" value="ROT80675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJB6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="44767" checksum="C6D8093D5682A089" modified="2019-04-10" version="1">MIIFRFGLLISFSLLSFPLLSPTSSTSLLLSSLFTSLSPLSSPLFPPLLSLFFYPLTFPYFLPLSLSFSFCSSSSCFPFSSLFLPSFPPPTLPSSHLSSSTFILPFYLCSPLIPSLKPFHSSFSFASPSPPLSPFILPILHFSSSIPPSLFSPLLLPPFLPRPVSLPPTLPRSSPSPLLPQTCFLFSTFSFSSPLLFYPPPSSSFPLPPSPFSPLFSPTSLSSPFLPSSSFSFPPSFPSLSLLPSSSPSPSPSPSPSPSTPPALPLSPPPLLLSSFPFPFFSSLLFFLPLPYSPSYPSPLPFPPLLPFLPLLPLPPFPLPPPPVPPPFPLPTPRPLLYLFLLLFSPFLPPPLSSPLSLPLPPPPSFPSPFLPHPFPLLLLILSEASLSSVQPPPPLALGREKRDARPLNLGEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJM1</accession>
    <name>A0A3R7QJM1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001052">
        <property type="protein sequence ID" value="ROT80904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJM1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="40522" checksum="3C7372CF37458261" modified="2019-04-10" version="1">MKVLARGQAPRSFPKATWSSTASNNPLGIRVSRESVCVRSRSLRLIIPPLFSLSLPTLRLSPSLLESALPYASLPGISASPYSPFYGRFVTRSSHFLSPLSLARRGSVSTVADERKPPPLLSLFLPLPLLPSIPSPFIALIPPPCTPPHPLPQPPHLPILLPLPLLPPIPSPLPSFCYSLHLPTFPPPPTPPPLPTLTLPAFLNPSTLSLTPTPTPLTNPARPPSLPSLPLPPSPPPNPNTSPSPATRHFPLPTLLTLFFNLPHFPLQPLPSFPPHKPPPISTLPNTLTPPVSTSPFPQHSFPPYSPQPPPFSNLHPFPTSLPLPPFLPHNLAPFPNPPFQHLTLPPFLHTLPPRLPRQPGLTPFTRTDFFSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJR4</accession>
    <name>A0A3R7QJR4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH2/MDH2 oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001035">
        <property type="protein sequence ID" value="ROT81023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJR4"/>
    <dbReference type="STRING" id="6689.A0A3R7QJR4"/>
    <dbReference type="OrthoDB" id="7881616at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.60">
        <property type="entry name" value="Hypothetical oxidoreductase yiak, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043144">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_ah"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043143">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036111">
        <property type="entry name" value="Mal/L-sulfo/L-lacto_DH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003767">
        <property type="entry name" value="Malate/L-lactate_DH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11091:SF0">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11091">
        <property type="entry name" value="OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02615">
        <property type="entry name" value="Ldh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89733">
        <property type="entry name" value="L-sulfolactate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="34848" checksum="9B05774CE856C498" modified="2019-04-10" version="1">MTSVATPTLQASALADLLVAADLRGHFTHGLNRLEMYVNDMVKKVCAGDATPVIIKESVSTALVDGKNGLGPVVGNFCMDLAIQKAKQTGVGWVCAKGSNHYGIAGWYAMTASKQGLMVESSLNSDCAIRTNPIALAAPGEKGDDFVLDMATSVVSGGKVEVACVKGEDVPAGWALDRDGAPTTNAERALDGYLLPLGGDETHSGYKGFGLGMMVEIFCGILTGAPYGSNIRDWTRTDRPADLSQCFVAVDPSFFAPGFEGRMTDLMNHCRNMEPEAPQKPVLVAGDPERLHMRKVEQEGGITYHINQINNLWKLAKYLDVTPLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJU6</accession>
    <name>A0A3R7QJU6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001016">
        <property type="protein sequence ID" value="ROT81109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJU6"/>
    <dbReference type="OrthoDB" id="6390065at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="119" mass="12497" checksum="793630E5F34E8F6B" modified="2019-04-10" version="1">MAGLRPLTPLLIKAPMLPDGADASEVPDGILPGTSRSPAEQIKMRTIFFLALAALATAEPGQSDVDDVNAPLDGDVHNRVKRDIGYDPDGYGPNINVDMEINAGPNAHVAIDVDVNIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLC4</accession>
    <name>A0A3R7QLC4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010588</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002342">
        <property type="protein sequence ID" value="ROT71121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLC4"/>
    <dbReference type="STRING" id="6689.A0A3R7QLC4"/>
    <dbReference type="OrthoDB" id="10004641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001049">
        <property type="entry name" value="zinc finger protein 319"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001289">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT71121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="16394" checksum="583B101282A5C8F7" modified="2019-04-10" version="1" fragment="single">VRPTGSSLHSQECPRGVRPFGCDTCGRRFSQKGNLLRHSLLHTNEKPFGCGVCRKFFVQKAHLVKHVVVHRQRLAALKRCRRREALERGSSAEAKEGALRCKVCGLQFRRIFQLMETPEGPAYSRKGREIVRHLSFVINALDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMQ4</accession>
    <name>A0A3R7QMQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000603">
        <property type="protein sequence ID" value="ROT84047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMQ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="59981" checksum="2259F65ED8F92622" modified="2019-04-10" version="1">MKEREDGRDQDHKREKETGRVRWVEKRRKRRRRAETDTNTDKQPETKDTKNQRKREKEPKQRKRGKEAKISRHREPSNKQKQTERALRSPPGAQRSRGREKDGCIRYRRVRVVEASLDRRVLYEGRARAGYETEGGVKAERGEAMNQLLLPLSLSNHCPPNSSIVSPSPFFFCYYLHSPSPLPPPSLKILPTSLSFPGPPRPLLFLSPSSPSLLLPFSPPFLPSLFFFPSSPPPCLAHLFPHSSPSSLPPPPLPFQPFLFHLPPSPLPLPPPPPSTPPPSPLLFHPSPFHPLPFHPLLLPLPPTYSYPLHTRSLSTPSSFHPLIPITSSPFPPPHPLPPLPLPLPPLPPLPFHLPSTPSLPPSPSTPSSFHPLPFHPSPSTLPFHALLLPSPSTPSPFHPLPLHPFHPFPTPPPSTPSLPPPSTPFPPPPSIPSSFHPLPSPPPLSNPPFTPPFHTPPLPPLPFHPLPFHPLLLTLPLPPSSFHPPLPLPRHPLPPSTRSLPPPSHPLLLPPPPSTPPPPSTPSPFHPPSFHPSTPSSPTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMY7</accession>
    <name>A0A3R7QMY7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMY7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018061">
        <property type="entry name" value="Retropepsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00077">
        <property type="entry name" value="RVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="498"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT72629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="533" mass="60390" checksum="75E91E6C98ED9673" modified="2019-04-10" version="1">MFDGIREWAIFKTLLRRKFRGTCSSTDFFTILNECRMTTTQGPQDFFQQLEGIVYQGVRDYPDVVGNPEPLLKRLFLQGLPLWLREYLAIIDELPLDRLVETAQRIWNTRTGVARTEPLADRHPPRPLRAVAPVEEPPEHRRTRWCSYHRTSRHDNTECRYRPRRLACFRCQQEGHLVKDCPFPPPSDGSAPVAGGTRWGQPLQYPRSSDTGAIARNSLNPTCSPRQGRPMVRLMISGKMINAFIDTGSEATLLKHSAQTLIAPSRTSEPRRRLQGASEHRLQSQRKAFTVRYVNKDSLELTAVVMKMKVIKPSSKEAVVWVVNPTLNPVKLRNGTHLVELHEVEEMCDTPEAPGNVASIADTPVAAVPTSALEKISLKHLSDHRRLVLYKIKTTQTGPDRALGPRWQGPAKVVKKLGPVNYVVQDLSPPFSERNCHANQLRPFKLEEELTFQMRHHTMTLITSTHGYLTTRSQVQRCCFQQYVHPNMHLSRGKTGYDHSNTSTSCGLSSETDVARTTNSYLELPECPGPPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRY2</accession>
    <name>A0A3R7QRY2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001701">
        <property type="protein sequence ID" value="ROT76015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRY2"/>
    <dbReference type="STRING" id="6689.A0A3R7QRY2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="42473" checksum="5F4D30FC1BEB455C" modified="2019-04-10" version="1">MGLGAPTATGTQANGKSGVISVNGNKLSTPITTSILLSTSEVVTDSQAALRGSAVSPRGGGAGVRVYSGSPKTSAASFLLTNVTSASNVRMASPSMVITNTLGVPPGGCATSASTEPLSLSMGSVVVSAGGVSNNGGGMVGGSGRGRVILTSSPRLVRPLMASPGSRPIGSTRMLNAPTASRPTVMLVTTATPGAAVSPSSATPGTLTTMALTPATNVTSPTLMASSTPMTSSTILAAVSKSPTNSAVLAQSKSSPLTLATSTSLLPKNITTQSAVSPKGLATAPVTTTRPSVVPAGELALLVAASEMSERARNPGSPTAMATEASIHIISSVDSSGAQPEVTVSPSAATSQSSPSASTPVGDKNCSNTASKANDTKKTAVTSSQQQDIYPKWRNQPKVEAEQRTSGGGARQWTSEQVIGQWVLIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QS46</accession>
    <name>A0A3R7QS46_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001678">
        <property type="protein sequence ID" value="ROT76229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QS46"/>
    <dbReference type="OrthoDB" id="163257at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="245" mass="27466" checksum="3E463BC3BD805E39" modified="2019-04-10" version="1">MSPNMRRGRSPSPRNRRSPSPRGRRSITPRGRRSSSIRGRRSVSPRGRRSPSPRGRRSSSPRRRPMSPPQSRYRRSHSRSPVRKKHGSASHSPRRGGPPPPAAADKKHNISNASRLMQLANYSADTIKEVQYKLTKKNENNHPASGSDESESDDGRMSRRVPKRRSRSASVSQSPRQRRRMDSGSVDGSEEEEEDEGSSSRESSPESESESGESMGGEELERKLREKALLSMKRQERSSAASESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QUW1</accession>
    <name>A0A3R7QUW1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TNase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QUW1"/>
    <dbReference type="OrthoDB" id="6220511at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042421">
        <property type="entry name" value="C3orf33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28434">
        <property type="entry name" value="PROTEIN C3ORF33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28434:SF1">
        <property type="entry name" value="PROTEIN C3ORF33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="2">
        <location>
            <begin position="251"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="40721" checksum="F5167019235B82E5" modified="2019-04-10" version="1">MTDLEVLATTSRPDIGTQWLPGSIPRTMSDDAPQPRPDFFTPLPRSFAKFTHFIDEHIRIIQYCVYGVGAAGIAITLHSVRAFTKFRTIPDIPKEFISKHVRLHGHVRWVGVSPPATATSPTLLSLPATHTSKSSESASDTQPPSSLESGSISSPLSVTKEEDKENGKRLKGGDSRSLSSDNRGIYDGAGELHPWDDGIDPDVDRIFYEEELRPVYLKIEHSPAIPLLRKGDDMCLPLHLADVEVSRAGLQRAKEQLMGKRAWFTLISHDADANTLVSIVKPVKFLRRKSLNEELVRNGEALVGPMDLDLFDDKAYSKFYSRLAQAQDYAERKKVGLWKPPPDPAGAISLLKRVWRRIKVLVGRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QV90</accession>
    <name>A0A3R7QV90_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Death-associated protein kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_001811</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001240">
        <property type="protein sequence ID" value="ROT79463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QV90"/>
    <dbReference type="STRING" id="6689.A0A3R7QV90"/>
    <dbReference type="OrthoDB" id="74764at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039788">
        <property type="entry name" value="NOL4/NOL4L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020859">
        <property type="entry name" value="ROC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12449">
        <property type="entry name" value="DEATH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12449:SF18">
        <property type="entry name" value="DEATH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00005">
        <property type="entry name" value="DEATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51424">
        <property type="entry name" value="ROC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="58"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="190"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Roc" evidence="7">
        <location>
            <begin position="262"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="Death" evidence="6">
        <location>
            <begin position="877"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="951"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="960"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT79463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="978" mass="106857" checksum="CAE9B08328BB0087" modified="2019-04-10" version="1">MPARPPWKRPRRSRSHSENKTLLVVTSSRLNTRTRTNANPTGLTAERRRTQQTLGSSHGETALHIAVWHGFPRIVHHLCSAAANTELTDKENQTPLHVASGRGHVECVRGLVGAGACVDCQDAHGATPLHHSLARHHTQAAMILLHAGANTDITDDLGETPIHIVAREGLLALAQTLCAFGCSVDVSNKAGLYPLHLAAKHGHTELVRCLCLAGCTVEQKSRDGILAEVSAMAQGYDDIADLLNKLRGEQQREEYIQQLIPSPSPIQRIKVKILGHSGSGKSALVETLKTGYFSSFFRRSKSNASSTSIGSAGKSTSAMKGHFEMESPVSSRQNSLTFEPCENYTRGIDVQQVNISGVGELSLWEFSGHEAYFPVYDHFIGNTSCVHLIVFPLNQPFDVQLQQCSFWMSFLQARIPPMEPLNVRGKPSKAAKVALIGTHADVAQCHRNAQGEYIAPQVHLLQEKLLDLFGDVFEVHDTVYVMDATAPGSAACRALKQYLADCKAKVTQGVPKVTGFLGAVVSTLADWRASLGEFPVVSWPQFVDVTHQRVNPLAGEEHLREVVQQLQLMGEVVYLKAEAQDLVVLDPSWLTHHQLGHLLSTQYAQHARVTGCYTVDDFQMSFPECDALDLLQVLEALHLCTQCDNDGEIEYEFPCFNQVETLDGLWEKGDPRYTNGVYGGVRLRSPAPTQYILPPIYIRMQVQLRRSWQEYPERDTDLYQWCGGSKFCSGPLEALLTLEEGGEAVEVKVRGPPEAGHVAFFFMEDLLAMIDQVLVEMCPGLVLEKHVLSAEQLSSHASTVYAWPPADIYTALLSGGVRASLQNPLTDKEESFTQLVCFGSQEVVSSIVVGGEVHISSLCTVTVQRLAALMDPAHPRGSDWCVLAVKLGLQQLLPSLDTQSGSAQHSPTATLLHSWGQSTTATLGTLVKELRGMEREDAAVAVMCGAPLYQLAPPDEDTTSDSPPISSTSATSTSNLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QY29</accession>
    <name>A0A3R7QY29_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000784">
        <property type="protein sequence ID" value="ROT82703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QY29"/>
    <dbReference type="STRING" id="6689.A0A3R7QY29"/>
    <dbReference type="OrthoDB" id="448455at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="127"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="23071" checksum="C5A21880539E3EB3" modified="2019-04-10" version="1">MHSTTSDYESMDSSLGSVSLANGSEPSSLTVRDSPEKSESLFNGQYSSLSPGYYNGYGYSKAPSPAPSWCSRKSHSPAPSGSWRRHRMHEGYSLPLDEFRMAAMQGNLPVIKALIKQGIAVDQILKSGWTCLMYACSSGKQHIVEYLLQQNADPNLHKEEEKRQQQRDTIQTIIKPERAEYPCDCAEESVMGHVCSRCHMCSLASLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SM19</accession>
    <name>A0A3R7SM19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lactosylceramide 4-alpha-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002922">
        <property type="protein sequence ID" value="ROT66525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SM19"/>
    <dbReference type="STRING" id="6689.A0A3R7SM19"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="3">
        <location>
            <begin position="259"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="348" mass="39724" checksum="59493C00F326AD60" modified="2019-04-10" version="1">MELMLKKLQSPRTLVVLAFITTATVVCVLPNTNQILVKVKNQYIFNNTEYDASEEYADGDQDSQENKTQTSAPEISIEWWQKELCKPEVLQLQPTTTYLRLPMLGRDIIPSPNDYNVFLGETACNPQPLYRAYCSVESYAHENPTAKVWYHTTSPLIDNGDGLFTNLEEAYENLKVVGTDLTKIFNGTPCEKVFMAGKWAHNTPWPANNISNLLRNVLLWLWGGLNSDTDCICVRNLTHIRNMVSYDEQDKVVNNAIMHFDAGHPFTYELMEYLKENFKVATWVVNGPGAATAIAKKVCGTEDLNEVLLHHCANVTLRPLKEMQLFRWPDWNNYFQDNKGERFAEASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SX33</accession>
    <name>A0A3R7SX33_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001249">
        <property type="protein sequence ID" value="ROT79417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SX33"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="485" mass="51681" checksum="2983E269CFE1F474" modified="2019-04-10" version="1">MEGQTEELQATVYFPLLSSLLFSLISPLICLLFYLLTLSSSSNLSLFSCFLILDLPLSIYSLHLDPHPTLSLLHRRPTFPLPLTPLSPNLRPTSPSSPHPLSSCTFAHLPPPSPPLSPVPSPNLLSPLPTPSLLPFTPPPLPLSPPSPPSSSCSSRLSPPSPHPLLSCTFTPLPLPPSPPALLRPTSLSPLTPPLSPCTFASPHPTLSPAPSPHLPSPSLLPLLLRPPALHVSLSLHPTPSLLYLRPTSPPPLSPPSHLTPPTSPPSTPLLPLLLLSFVLLLFTSLSPHPTPLSCTFAPPPSAPSPPLLLLSFVLLLFTNSKRRLTSSAAAPPLLLPSSSSSSSSSPPPPPLPLYFSPSFSLFLSFLFFFLLLLLYRPLPLPPLHHRPSSSSFSSSSSSFPPPSSSPSFHLLLHPTPSLCFLFPQKENSPLSPTLSPVPLSPALEPLSQTIPCPKLSIRTQFPTLVPTLTLSPALQPLSQPLPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SZW7</accession>
    <name>A0A3R7SZW7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000683">
        <property type="protein sequence ID" value="ROT83460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SZW7"/>
    <dbReference type="STRING" id="6689.A0A3R7SZW7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="44694" checksum="55CC94374D226CA4" modified="2019-04-10" version="1">MGRGRTNTTTLNPTSSHYPHLTHLCPVKSTPPSHPPTPTHLATSPSPLPISLPPYLFSLPSPSLFPSLPLPIFPSFYYSFPLTYFPSTYLLISFPLAYFPSLLPSLLPPYLFPFPLTYFPSTKPLPIPFPSLNLPYDTTHITPPQLSHYTHTPFPQLPPPLLPISLFFSSLNLQFFHHPLSLSPPSPLTTTPSPSLPTLNLPSHTTLPLFLYHHSPLPLTILTTVLLFPITTTLPFLYHPSPSAPPPLTPLNIILTSYHHLPLPPHFHTHSLHPYNSPLPFLLTPSLSYSLPLTSYSSLQPRTHPPSSSPPSLFSFLLPPSPHTSLPLPFLLPPQLLLIPLSPSYSPLPFPSSSPSPLLLQSPLNPLTLPSLFPPSLPPPLPPPFPLLPLHPHLPHPPPPPPSPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T1E3</accession>
    <name>A0A3R7T1E3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger, C2H2 type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_013878</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000273">
        <property type="protein sequence ID" value="ROT85455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T1E3"/>
    <dbReference type="STRING" id="6689.A0A3R7T1E3"/>
    <dbReference type="OrthoDB" id="6344823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="302" mass="33674" checksum="705FD9616EC43975" modified="2019-04-10" version="1">MDNFEYIFSYPSDVAASQYGSDAAGYAWTFGDVVGVSSRDIMDHLLGAPLPPPKRQCVRPPSDLSWCQPSYASYSTPFVGRPSESDLDAASWLASVSAPHEKEAISPSPAPVPPSVSQEFKSALGPVTVTFLSPQVTSSSTVPASSGRRRKNAHCHLCDKRFESRYKLKMHVNTHTGARPFTCDVCGKGFMRRTTLNAHRPIHDASQFSCPTCNRPFKRSSERLIHILLKVCLRKQRILRRTTSGWFCDVCNEGVPQPEEHRCPVKGRRRQCPVCGMDFGGQRDHKMLTHVRQDHPEFLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9H2</accession>
    <name>A0A423S9H2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_021468</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004500">
        <property type="protein sequence ID" value="ROT60883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9H2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT60883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="412" mass="45360" checksum="6EFAABD54A28C50D" modified="2019-05-08" version="1">MTLIVVGGASGRPFEITAHTRPKHKQLHVPTNDGRPHVPISPPTSPPPLIDLLKSFIYTVNSNGSHRSLAGDCTLLFPCLASSRFVRLASPFPFPFLLSRSPFPHLPRLACFLLGFLPSPRSPLLPHAPHASLLLLHPHFPSFPSTANKQRKNPFVWAGQGGGRGGALNLANPPSFAARGGGGSTSHSRNWTGKSSSFLLRRIQLRNRHELKAREATRDTTISRCPRRRFLDSAKKSFRFIEQRDAYLSLLGNAILLLVSTWQCKLFVGFLPQSPSQKQECSREREKYIFYSFLFFFSHILLSLLFPPLSLPLYHPISLLSPLPLPLLYHPLPPPSPFLTPPSPFITPPPPLPLSPLPPPSPLITPSLLPLPLSPPSPSPFITPPSSLSLYHPPPPSPLSSHHHPSLVPPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBR2</accession>
    <name>A0A423SBR2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">BRCA1-A complex subunit MERIT40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020562</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004062">
        <property type="protein sequence ID" value="ROT61644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBR2"/>
    <dbReference type="STRING" id="6689.A0A423SBR2"/>
    <dbReference type="OrthoDB" id="547311at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070531">
        <property type="term" value="C:BRCA1-A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070552">
        <property type="term" value="C:BRISC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045739">
        <property type="term" value="P:positive regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21502">
        <property type="entry name" value="vWA_BABAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026126">
        <property type="entry name" value="BABAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15660">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15660:SF1">
        <property type="entry name" value="BRISC AND BRCA1-A COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="263" mass="29465" checksum="B308009AC3B8AFE3" modified="2019-05-08" version="1">MAGEETSSSCSTPSEAHEATEQLGCVTVERHVPRVNCPEHIILVIDVCKEEGNTPYKLADGTKYSPMYMMKRALTLFLQNKHAIDSRHKFALMLLHESPVWLHDFTSNPKDIIAELDELEEAVTSGSHFDLSHLFSLIANQVSVPHCSNPAVAPPPYVIRTIMLYGRSQCLPQFLSGKTSFTNLSQSPHYFLDILYMHETPSDDNKCEGIFDLLCGLDESGWSYVLEVSRNATKLHNHCGSLLAHPLQRPTQKDVHYTLVATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEA7</accession>
    <name>A0A423SEA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Retrograde Golgi transport protein RGP1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003642">
        <property type="protein sequence ID" value="ROT62538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEA7"/>
    <dbReference type="STRING" id="6689.A0A423SEA7"/>
    <dbReference type="OrthoDB" id="1918at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014848">
        <property type="entry name" value="Rgp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12507">
        <property type="entry name" value="REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08737">
        <property type="entry name" value="Rgp1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="43200" checksum="B2F9EAEAD0A7DCBE" modified="2019-05-08" version="1">MVEVQAQVLGGPVHLAGDTVQVCITITVPSLDPALRAQSSDVCEVLAWGSAQIHCQCSVNESRVRLPATSPKQAEERAVTNADTSFAPCRGERGHVVLSTKPKILFCDLQLLPGESRSFVYRETLPCDAPPTYRGQLLKYAYKITIGVQRLGSPIKLLRVPIRVIVLQGLSEACVYSESGELAPSNPFLHTPQRDTPRHTALQIIQNLSTRKNVNQYNITNTQGKVVRFCIYKTSFRLGEDIVATFDFSSAEVPCVQYSVTLQSEEVISEACRQRPSQKPMLVPYSKAHEVCLNMTHTNLLLPIPLHVTPTFTSDLVSLQWRLHFEFVTSKTEVPGPSTPQNAEDQIEWRAPSSLEIETMVWDLPITVLPTTPSQVAQAICMPAQQTLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMQ8</accession>
    <name>A0A423SMQ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Serine/threonine-protein kinase TOR</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_016559</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15" key="3">
        <citation type="journal article" date="2020" name="Fish Shellfish Immunol." volume="96" first="53" last="61">
            <title>Functional analysis target of rapamycin (TOR) on the Penaeus vannamei in response to acute low temperature stress.</title>
            <authorList>
                <person name="Liang Q."/>
                <person name="Ou M."/>
                <person name="Li Z."/>
                <person name="Ren Y."/>
                <person name="Wei W."/>
                <person name="Qiao X."/>
                <person name="Hu R."/>
                <person name="Wu X."/>
                <person name="Liu Y."/>
                <person name="Wang W."/>
            </authorList>
            <dbReference type="PubMed" id="31801694"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="MN398907">
        <property type="protein sequence ID" value="QHT73480.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01003082">
        <property type="protein sequence ID" value="ROT65480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SMQ8"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016242">
        <property type="term" value="P:negative regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045930">
        <property type="term" value="P:negative regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045787">
        <property type="term" value="P:positive regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000243">
        <property type="term" value="P:positive regulation of reproductive process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038202">
        <property type="term" value="P:TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05169">
        <property type="entry name" value="PIKKc_TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000060">
        <property type="entry name" value="Serine/threonine-protein kinase mTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000007">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.150:FF:000001">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000004">
        <property type="entry name" value="Serine/threonine-protein kinase TOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.150">
        <property type="entry name" value="FKBP12-rapamycin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009076">
        <property type="entry name" value="FRB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036738">
        <property type="entry name" value="FRB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024585">
        <property type="entry name" value="mTOR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026683">
        <property type="entry name" value="TOR_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF9">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08771">
        <property type="entry name" value="FRB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11865">
        <property type="entry name" value="mTOR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01346">
        <property type="entry name" value="DUF3385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01345">
        <property type="entry name" value="Rapamycin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47212">
        <property type="entry name" value="FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="13">
        <location>
            <begin position="1343"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="2069"/>
            <end position="2384"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="14">
        <location>
            <begin position="2431"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QHT73480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT65480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2463" mass="279402" checksum="7735B299571373AE" modified="2019-05-08" version="1">MSNVKMTQFVAGLKSRNEETRVKAACDLQRYVTTELREVSLDELLTFLDEFNHHIFEMVSSNDINEKKGGIYAIMSLVDVDVGQTGVRISRFANYLKNLVNSPDTGVTELTAKAVGRLALASGTFTAEYVEDLVKRSFEWLQGDRNEGRRHAAVLVLRELALSVPTYFFQQVQQFLDVIFNAVRDPKPQIREGAVAALRVALAITAQRETKEMQQTMWYKQCLTEVWAGFDDQANNKDRSLTRDDRIHGSLLVLNELLRCSNTEWERLVKQLRHLTHYQTPPPKKDSMSSVVKRLRGQGSLSSSSHTPHDLLSALPSHTNNTIGGTEITILDQPCESRTCRELILEKYDSISTQVLNQKTSRNNIIQSALLQIIPRLAALNKEKFSQSYLSGTMTYLLGCLRGRDKERPTAFITLGLLAVAVGPAIKKYLPKIMEVIKASLPTKDTPSKKRVVEPAVYVCVSLVARGVEGAVRNDVKELLEPMMATGLSPPLTLALQELATEIPSLKRDIAEGLLRMLSQILMHRSTPHSRSGVAPPPSSPDHQDTGSLVLALRTLGSFDFEGTGQSLMQFVRHVADHYLSSEHREVRLEAVRTCCHLLRPTFASLGRRASQSQTHIIFNIVSKVLWVCVTDMDPDVRLCVLASLDESFDSHLAQPENLNALIYALSDEVFEIREHAITILGRLSAINPAYVHPLLRKALLKILDELDYSGIGRNRELSAHMLGQLIGNAQRFMRQFVQAIMSVLVPKLKDQDPNPAVTMYVLMAIGDLAQVSGGEMQKWLPELMPLLLEMLADGTSGWKRRVALWTLGQLVENTGYVVHPYTQHPTLLDVLLSFLKTEQQPAVRRETIRVLGLLGALDPYKHKMNVGMIKIQEDTGVAVISTSENKTDELSGEMGTSEMLVNLNYSSLEEFYPTCAIAMLMKVIKDPTLGQHHNEVVRAVTFIFKSLGVKGVPYLAQVIPSLLYVIRTADANFRDYLFQQLATLIGIVKQHIRNYLDDIIEVLKEFWVTGGKLETTITIITVVESIALAVGSEFKIYLKELVPMILKSCINDSKEKQVTGKLLLAFQKFGATLEEFLHMILPHIVKLFDASDVPLSVRRTALETVDHFADYLDLSDYTSKIIHPLLRTLDTCPELRDQAMEVLCALATQLGRSYECFIPIVYRITTKHKIHHPRYDILVAKVVRGLTVSDDEMTIITAHQRARRPRSRDHQLEADSTTIKKHTVGVQSLQKAWLFTRLVSKDDWLEWLRRFSIELMKASPSPALRSCYSVATTYVQLSRDLFNAAFVSCWSELNESLQDDLLQSLRQALTSQDIPEITQTLLNLAEFMEHCDKGPLPLELQLLGEKAMECRAYAKALHYKEEEFHKGPTSEVLEHLISINNKLGQKEAAAGLLEYARKNNRTDMKVQERWHEKLHDWDQALQAYQTKLETRPDDLELTLGQMRCLEALGEWGELYSVSCEWWSSSMNDECRAQMARVAAASAWAMGQWTSMEEYTKFIPRDTQEGAFYRAVLSVHKDQYPVAQQLIDSARDLLDTELTAMVGESYQRAYNAMVAVQMLAELEEVIQYKLVPERRQPITQIWWERLQGCQRVVEDWQKILQVRSLVLSPQEDMRPWLKFASLCRKSGRLTLSHKTLVRLLGCDPSTNTQQVLPATHPRVTYQYCKHIYTYPNRRHEAYGHLQNFLQYIAPAVGVGGCHNNDNKLRELVSRVHLKLGEWYEQLHGLNEDNINTILTYYTHAKDTDKLCYKAWHAYAYMNFEAILFYKNKADSGKAENGDDTSTPSKKKKSAGDFTIAAVKGFIRSISLSDGNSLQDTLRLLTVWFEHGHQSGVYEALVDGLKTIQIDTWLQVIPQLIARIDTPRTLVGKLIHQLLMDIGKHHPQALIYPLTVAAKSSVVARSQAAEKILKNMREHSANLVQQAMMVSEELIRVAILWHEIWHEGLEEASRLYFGERNETGMFRTLGPLHAMMERGPQTLKEMSFNQAYGPDLRDAQEWCRRYQRTGNVRELNQAWDLYYHVFRRISRQLPQLTSLELQSVSPRLLKCRDLDIAVPGSYAPNSPVICISQVQSSLQVLTSKQRPRKLCIRGSNGRDIVFLLKGHEDLRQDERVMQLFGLVNTLLISNPDTFRRNLTIQRFAVIPLSTNSGLIGWVPHCDTLHALIRDWREKKKILLNIEHRIMMRMAQDLEHLTLMQKVEVFEHALEHTQGDDLARLLWFKSPSSEVWFDRRTNYTRSLAVMSMVGYVLGLGDRHPSNLMLDQLSGKIIHIDFGDCFEVAMTREKFPEKIPFRLTRMLINAMEVTGIDGTYRMTCESVMSLIRRNKDSLMAMLEAFVYDPLLNWRLMDHAQPKSKRSVVGETVSGGGVAATDPGHTPIMEAASTSSGAPTGSQTKKMEVREDSGASEALNKKAVAIVNRVRDKLTGRDFNNDEPLDVHKQVELLIAQATSHENLCQCYIGWCPFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SMT7</accession>
    <name>A0A423SMT7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tektin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_016541</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
            <location evidence="10">Cytoskeleton</location>
            <location evidence="10">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the tektin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SMT7"/>
    <dbReference type="STRING" id="6689.A0A423SMT7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048256">
        <property type="entry name" value="Tektin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000435">
        <property type="entry name" value="Tektins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19960">
        <property type="entry name" value="TEKTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19960:SF25">
        <property type="entry name" value="TEKTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03148">
        <property type="entry name" value="Tektin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00511">
        <property type="entry name" value="TEKTIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6 10" id="KW-0969">Cilium</keyword>
    <keyword evidence="5 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="11"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="73"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT65510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="43263" checksum="48B04BC8539430B1" modified="2019-05-08" version="1">MEVNPDLVPLSRPPPHPTLPPPPPHTSYPHPRPPPPHFPSHFLPPPPPTPHFLPSPHSPPPHFLPSFLSSPSLPTPHFYPPPHLLPSPHSPLPTAPHPSLPSPHSPPPHSYPPPTPTPHFLPSPHPHPHTSPPPTPTPTLPTLPPLLADPACPLVPYHLEKNVQDKDGAIKVEEETRRLTATAHPTDIIHGQTIDPSPVSVDWWKATGVKLLERADHEHELSVQVLAVSEDILVAAGRHLKERLEHTDLCLATRVKDTRHAKTLLEEHHAKLVEEESQLEKSLVEVEDQLEAKRGPLALAQTRLHTRRRRPNMERTRDEVEAALLKEVEELELTISRLSSAAATTREQIQKIKSTRVSLQHDINLKAKTLLLDEVEVLGLRSSVKIDTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPA3</accession>
    <name>A0A423SPA3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ionotropic glutamate receptor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015987</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003001">
        <property type="protein sequence ID" value="ROT66011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPA3"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="11">
        <location>
            <begin position="140"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="376"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="45269" checksum="69709B4084976900" modified="2019-05-08" version="1">MKQRSFALSSHPHPMPPRFLYGAQGQAVGSAESQRRVDGDGERGHGGRADLIGGLIILSSRAEVIDYSIAIQQTWNMIVVRKPSSKDMTWTSYTKEFTPWAWAGVGVLTALAPCILLLGEKQPEGGPAGRSRGLLPAHDGMMTQQGSEMRVSSTSCRIIFFAMFVSAQLIVMHYSSFLISMLSVSNNILPFKNLEELHRTGDYQLGIWKGSFTEDTFRHSDIPLYKAVWRDMVEGRPGSLTYNPDGVARVLEGKYAYIMTQQEFQYSYSDDPRLVTLPDKAGIFYMALGLRKNSPLKPIIDEQITRLRSSGILNLFEIKNSKQALAFSRTNAPSLSLQNVGAAFIILASGGRARCVFSWRRRSTPSTRALRLVLGRRRSGASPRSQPGARVAPTALCRRGPSPPWQGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPS6</accession>
    <name>A0A423SPS6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hsp90 co-chaperone Cdc37</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015778</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002974">
        <property type="protein sequence ID" value="ROT66226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPS6"/>
    <dbReference type="STRING" id="6689.A0A423SPS6"/>
    <dbReference type="OrthoDB" id="440202at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.610:FF:000001">
        <property type="entry name" value="Hsp90 co-chaperone Cdc37-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="8">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="7">
        <location>
            <begin position="155"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="219" mass="25938" checksum="B146AEDA4F04D75C" modified="2019-05-08" version="1">MGRKDESLSEEEKEKRMKEFVKKNEVEIKKYGMFRNYDDSRRYLMEHPHLACEDTANYLVVWCINLQMEEKTELMAHIAHQTICMQFILELAKQLERDPRSCISAFFHRIQQAEPEYKKAFQDELDGFKDRVTKRAKQKMEELIKEAEEEERQERLGPGGLDPIEVMESLPEELQKCFESQDIELLQKTIEKMKPEDAAYHMKRCVDSGLWVPDAKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPU1</accession>
    <name>A0A423SPU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002975">
        <property type="protein sequence ID" value="ROT66213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPU1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="45780" checksum="50ABE420431CCE8F" modified="2019-05-08" version="1">MHATPSAGVFGSQCQSSAVAPFLCKAPALQPLLSLLLPLTPRFFHQHFHGEFSAYDCLTIPIGKDLSHACQICVNNAKAANKGLACVLPVSRVLESLTMLPTPQILARSPSALRDNASPGLFRETGGSLQIAELGDYVYHVQGNERPRRRKGGGCQDFFPLGAPLVTLVRKFALLPLRRRIHKLPPRLAKEAEGREANEVRGASGNFSRPMLRVEVIDLTEFVEHLLSWRRPTPAPSEGDAAADDDEGKASSRQKSLCADCLGTQRRPDAQVLSPSPRPSPYHPTQPTSHLPNPLNPPTFLHTPSPPSPSEIDVPTPTLANPTPRTKLGLQCGGEEGEGESPHEHRPQGTHGELTAAGTGQLSLSGGGAAPGGSEGRGHQEVKGGGRHQGVKGGGGAPGGQREGAPGGSEGEGRTPGGSRGDGGGTRGQRRAGTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQK6</accession>
    <name>A0A423SQK6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002924">
        <property type="protein sequence ID" value="ROT66500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQK6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="56085" checksum="AAE876073D2B8A4E" modified="2019-05-08" version="1">MATICNTREIHNDLGQKAWETCASRGHLACAEFLCVHEAGLALAGDVTRREAELEAAVADNAEFRTSFKEVVGIARRLAKEREEAFRELAKLREYMVEAHDNVVMALQVLAEENTLLRERKVWFGTMVDVVDLRHKMVDVEDSWKRLRAKNHRTVATAHHPLDVFSPCPPPNLTHAGPPFTHSPTSPTPPPHPHPHLTPHPYLTHGPPPHPHPPHPRPNLHPRPLPHPRPYLTHTLTSTPRPHLIPRSHLTHAPTSPPPPPHPNPHLTHAPHLTPHPTTSNPHLTHTLTLPRSHLTHAPPHHAPHLHPKNPTTPKPPPHPHPHLNSTPHGHPRPLPHPHPHLTHAPTSSTLPTHPRPLTSPKNPHLTTPPPHPQRPTTINPHSQPTPPPHPPLPPYPRPHLTHAPTSPNTPTTPNHHLTHTPTHPHLHLHHAPFSPHAPTSPKPPSLTHAPNLTPTPTSTHSPTSPAPHSHRAPTSPTPPTSSHAPTSPRPHLTTPPTRPANRPAHNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQY7</accession>
    <name>A0A423SQY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002916">
        <property type="protein sequence ID" value="ROT66626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQY7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="676" mass="76711" checksum="5ADEDECBA2C5DA89" modified="2019-05-08" version="1" fragment="single">MQAAARARMQAHLNTYTHLLNTYVHLPQAHLTHTAHSTTFPQAHLNIHTPSTSTPQHICTPSHTHPQHSHTQAHLNTYVHLPTSTTPTHMYTFPQATSNTYVHLPQAHLTHMYTFPQAHLNTYVHLPTSTPQHICTPSTSTLHSTSTQHICTPSTSTPQHVHLPTSTPHTHTTPQHICTPSHKHTSTHTHTFPQAHLNTYVHLPTSTPQHIRTPSHKHTSTHMYTFPQAHLNTYVTHLPTSTPQHICTPSHKHTSTHSHKHTSTHMYTHTPNTYVHFPQAHLNTYVHLPNKHTSTYTFPQAHLNTYVHLPTSTLNTYPPQAHLNTYVHTHLNTYTHLPTSTPPHSHKHTSTHTHTFPQAHLNTHVHLPTRHTLNTYMYTFPQAHLNTYTHFHKHTSTHTHPSHKQTSTHTLPTSTSTHTYTFPQAHLNTYVHLHINTYTHLPQAHLNTYTRTCQHITPQAHLNTYVHLPTSTPQHIHNKHTSTHMYTTSINTHLPTSTPATHSTPSHKHTSTHMYTFPQAHLNTSPQDTTHHLPTSTPSTHAHLTLQHAHHTSTHTPSHKAHLNTYYSTPSTFPQAHLNTHTFPQAHLNTYVHLPTLNTYTHKHTHHGGTPSTHMGTPQHIGGTPSTHMYTFPQAHSTQTPSTHTSTHHTSHKHTSNTYTHLPTYLKTSTPQHIRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SR73</accession>
    <name>A0A423SR73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_015225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002897">
        <property type="protein sequence ID" value="ROT66732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SR73"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT66732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="20215" checksum="DD581C9FE63D4914" modified="2019-05-08" version="1">MERRQWLILETNADEAGAVVQVPPSLDHLRQDDLPPNSHPKFHLRCLRDRRRHILRPVIPGNYVVRRPKISCSWRRRRRTRTNRPRWRRVWRRFAPMSRLGFTAECGGGRKDAATQHGNRSLHLHLRRHRVCGHLDSAAAFVVIRDWPNRRGAATPSPLSLPRLLCFAETWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSZ6</accession>
    <name>A0A423SSZ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014612</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002822">
        <property type="protein sequence ID" value="ROT67322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSZ6"/>
    <dbReference type="OrthoDB" id="6347961at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.30">
        <property type="entry name" value="Nonribosomal peptide synthetase, condensation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="435" mass="48338" checksum="C78BAB5DDAFBBF21" modified="2019-05-08" version="1">MLATKRLLPRLPAAASHGLPRCLAGPSRAPRFSHAASKSAENGVLWLHPAGGTIERLDVAAKYAQLNLLGCLTINSCLPLEPAHFEEALKHLHRKISPLRACFRWREGTLWVCEALDPQLDFLVLKDSDVTTTINNLLIQPFENSAEAPLWRARLLPAAPGVPCPIPEMKEKFPHQYDLMLHIHHGLSDGITGFVIFSTFLKLLEAVVLGSPISKEQLGKLVSGKQSMDIEGEVLKNLESRPDEFQRMIDETANTKFTPLLEQAFGTPEEGISPTEYVMTDIEPRLLQNFQERCRSHGVTVNSGMTSVINTALVELVADAGLERDVYSITSRHPVNLRRYWNGDPVTAMGNHMGAISHTMQIPRHNRNTFWEHAKRLIPSSAGSSMTGTSSGKIVRSKTLPKDYSHDSFYGSPPTSIYDYMFSSHLPLQLLTPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXF7</accession>
    <name>A0A423SXF7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_012891</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasmic vesicle membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Early endosome membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002618">
        <property type="protein sequence ID" value="ROT68940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXF7"/>
    <dbReference type="STRING" id="6689.A0A423SXF7"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002376">
        <property type="term" value="P:immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000043">
        <property type="entry name" value="Putative e3 ubiquitin-protein ligase march8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45981">
        <property type="entry name" value="LD02310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="18" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="14" id="KW-0391">Immunity</keyword>
    <keyword evidence="17" id="KW-0458">Lysosome</keyword>
    <keyword evidence="16 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 21" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="23">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="22">
        <location>
            <begin position="42"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT68940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="293" mass="32905" checksum="F76A87E8915E93D9" modified="2019-05-08" version="1">MTGSDSDFLPFQELYDVRTVPAPPMERCASHTSTFSFSQDICRICHCEGDADSPLIAPCYCAGSLRYVHQSCLQQWIKSSDTKSCELCKFSFIMHSKIKPFNKWEKLDMNGMERRKIACSVTFHVVAITCVVWSLYVLIERTTEEVQEGSLEWPFWTKLIVVAIGFTGGLVFMYVQCKMYVQLCKRWRAFNRVIYVQNAPEKVPLSERDRTEFQREASQQCAAPRDLTPTTTTTLSTTPFSTNTSITTTTIATTNPTITATSPPGAVWTEAPTTPLDSQLAFSTGLTATALLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0R3</accession>
    <name>A0A423T0R3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Neurotransmitter gated ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011650</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002470">
        <property type="protein sequence ID" value="ROT70080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0R3"/>
    <dbReference type="OrthoDB" id="6352648at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="14">
        <location>
            <begin position="77"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="439" mass="50065" checksum="4AD4DC2971E98ADD" modified="2019-05-08" version="1">MIQNNPDDLPVGLHQWLISGDGCPAGEVDLLLTVCGEESFPCNDGTCVHMSQRCDLRAHCDDGSDEMECDKVFVGTDYEKTLPPPPPETEDVLNVTLSLVIHAVHDLDLLAQTVRLDVLLTSQWEDARLLYADLHSEQFRNEIQDPDRLWLPRFTVTDDTGSRVRIEERGSSLRVLRGSTPLPRENTRAVKGKLRTTVYPGRENVLFLRQELSIAFQCQFDLRWFPFDNQRCSINLRFADMESKLLRMLGTKARYLGQKKLHEYKVEFIDMTEAKLENGQRVSLCLTNLFVYYLVNSYLPSFLLVIISYSTFYFPLEGFNERIMANITAMLVLVALFQQPCSTILKTTYLKLIDVWYMICIVVDFIMVILLVMIDYIRNLGDNVTKVFPASAGVKTLFAAENMPNARKFNTIAKMMLPLLFLLLFGVYGSISAIQYSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3E6</accession>
    <name>A0A423T3E6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002351">
        <property type="protein sequence ID" value="ROT71030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3E6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003109">
        <property type="entry name" value="GoLoco_motif"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50877">
        <property type="entry name" value="GOLOCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="490" mass="54202" checksum="C9856DB464201884" modified="2019-05-08" version="1">MREMVMREMMTMTRCPGERGREREGEHRRIITNPPPPPSPLSTCRHGAFLVSVSLKKVARAVLSPKTPLRNHLHYPGLFGLVMVSGWNGSVFPPIPALSEAIPVALLSPSHISPSHPLSLYSLPFDHSPLSPSPSLLLTPLSFSPSPPLSSPLSPSHPLIPLTSPLSPSPPPLPCDVEIACCLAPAVQSKGVDGGLYLPTQTRDDRSEAAGDYMLELLDRMSKYRLDDQRCSLPHTFNQHPQLTNVSEYEAELLNLLPSTYQCPVVSNLKGRCRALYSLSFCVASSTTRPDPTRRDTGLLRRRLSVGSGSLGKKRVLNAMRRAIKKEEIKNDGASSLTAPTYHSSILEAVLSEGCRQDTLLLQDTFASSPLRKVCHQHRRSINFIGDSPAWKLNWRASRTGPVSPLASSGPVCCAASFVSWVRISGLCERTFDTFLFLLVLLRSFISNSFNASRSSSFLSFQLVQRFSFFFVPFFPTRSTRILQNLRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3K3</accession>
    <name>A0A423T3K3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Estrogen sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_010605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002345">
        <property type="protein sequence ID" value="ROT71086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3K3"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="161"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT71086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="47760" checksum="28CB656F005D211A" modified="2019-05-08" version="1">MSLKVKAPYGMTAHAASLATVCADSSRCSRASVSNCCVSSPTVTIVGLASAACNGLRREGCEGLESELLVAQVPLRTSLVLEETRGGGRVRYAEMPSSGEPTTLASGHVAVPLETEDMKRIYRNFPTFTDGASRLYPGRWLLLTGFKDVADRIYNFKIRESDVVIATFPKSGTTWSQEVVWSMLHDPDLKDAPRSPLMDRPPYLEMEVDQWPAEVKSFVPPLFHAMCPGGDASRGTVVQMLEVEKEPRVIKTHLPLSLLPPDTLDKAKVVYVARNPKDLVTSFYDYSRTQKRLQFQGMRFCPYWEHLREAWQKRDHPNLHFIFFEDLKKDSVREYRKLDEFLGSRLSEEQLARVMEHTSFSSMKARDEALGKCDQIISEGSFFRSGQAGSWKQKLSPDLENKIDTWTKENVADFGSDFKYFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3X5</accession>
    <name>A0A423T3X5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002325">
        <property type="protein sequence ID" value="ROT71226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3X5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="608" mass="68565" checksum="6D08FA6663914E00" modified="2019-05-08" version="1">MFFLFSFLCFSLSFSLILFFRFYSFLFTFSLVLSFFLSFPLLLSRPSVFSFPCFSLSFSHSFVSLYSISLLLFFGSLFALVSPSPLSLFLFIAFLSLSFRLHCFFFSSLFSFLLLLFFFFFFYRLPCLFYLPRISSLLLHLFLSFLSPLLLRSPFLSFFSFSFSPLFLIIIFLHLSLSFSTLYCFSSISPLPCFSSLSVSTFSFYLFLAFSVFLLLSAILFHLLILFLFSSHPVTPLSPFISLSFCLSPYPFFLLYFSSLSFFSISLPFLSFLFLYFFLSLPLSFFLLYYSSSLSLPSSLLFLLFLFPFYPCFSSPRFFSLTSCFSSSFFLIHLSSSPSLLFLFFPPFPSVSCFSSSLFSPPPSLTPLFLSPRLPLSCSFVSIITLYSFFVSLSSPLFISSLSFLSLLTLLSLSSLTSLFLLPSFFLHSLSPPCLFISFLLPFIPFSSVVSPLSPSPYPSVSLPPSSFISSPFAAFFPPSPIPCPCFSLLLFPSFSILCFFSPPPFIPSPLSPSLIPCFSLLLFFTPSPSFFSLLAPPLPLCFSLLLPLPSFSLLCFPLSLILSLPPCLFIRFSSLSLPYPSVSLPSLFLHSFSSVSFSLPLSPFSHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAJ0</accession>
    <name>A0A423TAJ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7153 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002023">
        <property type="protein sequence ID" value="ROT73513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAJ0"/>
    <dbReference type="STRING" id="6689.A0A423TAJ0"/>
    <dbReference type="OrthoDB" id="6060890at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055577">
        <property type="entry name" value="DUF7153"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22198">
        <property type="entry name" value="FERM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22198:SF1">
        <property type="entry name" value="FERM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23672">
        <property type="entry name" value="DUF7153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7153" evidence="2">
        <location>
            <begin position="286"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="472" mass="51335" checksum="FAF47BCDB0E70177" modified="2019-05-08" version="1">MIAFPSCSSGSTRGNINSFALNILVITSVYDRNLVESDCRVRCCVMLAAKTYASRHGTVSRGTGGTSSSRSVGVSFSRSSGTSSSRGGGGAAASRGSHAQGCDCEVCASEFPLRTHPFLDMSYSRLNQDQKPSSTSKFSFFSRKKPSSHTPAHTAAALALAQEQRRASARAQLQAQQEAEAMARALQEPVTLGTLKQDSLMIPVAKMKQFFPAGHPIPTIASQGRLRLLEAPEHSIHVVFHMMGSAVHVNAALRSPLLDSYAHQRECVVKAFKAAVSAANVGAGTLQGMVLLNLERGGEMGAVEFPFMIVWFVDGRQCDANQLIGRVRQSSLETLDPMKTGFTCSHYFDTFEEVATLARPPLEKMQRKPSSAHTGYIITVFRVFEGNDGVKFERNWLGWTGARTLYKSLTSEVGLKRITLHKSSPQNGTLHYVLMCDCTNFLTCFNKAVKAVPSLRMRLCGDTGLYRPICSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCP8</accession>
    <name>A0A423TCP8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative cubilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007267</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001919">
        <property type="protein sequence ID" value="ROT74239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCP8"/>
    <dbReference type="STRING" id="6689.A0A423TCP8"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251:SF37">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24251">
        <property type="entry name" value="OVOCHYMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="77"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT74239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="193" mass="21450" checksum="7626DE6A08D4C815" modified="2019-05-08" version="1">MQVVHPASPVQVSKKKLKKCVDFVGIQIPYNRTVKLCGARKGSIFVPNLNLEANFVTDNAVTDVGFNVSITWQKTECHRVIELSDDSATGVIQSPRFPKKYPKNSVCEWWIVAPEGKRIQLEFTQINIRDKKCLNAYIAVDRSGKASYLRDDSSLLCAAHKSADVLSDGNTVNVAFAGGRRRSRGFSARYTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCY9</accession>
    <name>A0A423TCY9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001909">
        <property type="protein sequence ID" value="ROT74350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1660" mass="183560" checksum="59F09C3CA347A215" modified="2019-05-08" version="1">MPSETRVCSWLDCDSTAESSRVIVQMRHEKGKKTNRSRKEEYEEKREGSGKLFSRFPSHQSRAFPLVPLAFPFPAPRSLSVFDAPLGLSRFPCPLAFLVTSPFPFGPLRFLGPSRILLFLSRFPLSSRVPFRPLAFPCPLPFPSVLSLLSRSLSSPFPLDPLVFLGSRVSLCPLAVSLSSRVSLGLSLSLVLPFPLLLSALSLGPLPLSIGLSTFPWSSPFPWSSRVFPWSSPLSLPLLFLVLSRSLVLSFSLCPLAFPLFLIAFSLASRVSHWSFLSLVLLRFPCLSRFPVSRVSLVYSRFPWVSRFPCPLRFPCPSRSLDPLPFPCPTSRVSLESSPISLVLSRFPWSSSPFLVLLPYSLSLASLVLSRFLVPLALPLVLSRSLVLSRFPCPLAFPLVLSRFLGPLAFPLVLSRFPCLSRPCPLASLSSFPRPSLPLSLRSFVLSRFLCSFAFPLFSRVLGLSRSLSSPIPCVLCVFLGPLAFPCPLAFLVSRFSLVSRVSLVLSRFPWSSRPFPWSSPFPLSFAFPLSSRFPGPLALSLDPLAFPFVLRFSLGLCPRVSFGPSRRSPLVFAFPLVLSFPLVLSRFPCVLSPFPCPLAFPLVLSRFPLCPSLSLSFPSSPFPWSSAFPIGPLAFPFTPWSSRFSLVLAFPCPLVSLSLAFPSGPLGPPLSFVPGPLAFPCPLRFPGPLAFPFVPWSSRFPSLAFPVSRFSLGPPFSLSSRVSLGPLRFPFVLSRSLLISLSRFPCSLAFLGLSVSLCLSLPGPLAFLLAVPWSSPFPLSSRFPLVLSVSPSPFPLSSPFPCPLAFHFLSLPCPLRFPCPLAFPWSSCFSLVLSRFPWSSRVFPWSSPFPLVLCVLSLSLVLSRFPCPPRVSLVLSFSLVLSRFPLSSPFLSSRVSPLVVLSRFPCPLPLVLSRFPWSSRFPLSFRVSPLWSSRVLGPLAFPLVLSRFPWSSRFSRPRFPLAFPSRVSLGPSRFPGPLRFPWSSRVSRPLSLRVPCPLAFPLSFGLVLLRFGPSLVFPCPLAFPCPLASLSSRFPWSSRFPWSSRVSLGPLAFVLAFPLSSRVSLGPLPFPFGPLAFPLVRPLAFPLSSYFHSSSRVSLGLLAFPLVLSRFPWSLARFPFPFAFPLVLSRFPWSSRFSLWSSRVSLGPLAFPLVSLVSSPVSIRPPFPLVPLLSFPSLAFPWFSRFHSSSRVSLGPLAFPLFLSLFPWSSPVSSSPRFPPIRPLAFPFRSSSRFPCPLRFHSSSRVPLVLSRFLSRVSLLSRFPWSSRVSLGPLAFPLVLSVLSRSVLLRFLGPLAFPLVLSRFLGSLLLLSRSLVLSRFPWSSRVFPLVPCVFHSSPRVSVLVRVSLGPPLVPLAFPLVPLARSLVSRVPFGPLVPCVLSRFLVSRRFPCPLAFPLSSRFPCPLRFPLVLSRFPWSSRVSLGPLAFPLVLSPFPWSSRVSLGPLAFPLASSWSLRVSLSRFPWSSAFSWSSRVSPLAPSFLFSLGRSPSSRFPWSSRVSLGPLAFPLVLSRFSLPLAVLGPLAFPLVLSRFPWSSRISLGPLAFPLVLSLFPWFPPFPSSRFPWSSRVSLVSRFSLVLSLFPWSSSVLSSPLVLLRSPLAFPWSSRVSLGPLAFPWSSRISLLSFPLSSRVSLGPLRFPCPLAFPWFPLVLSHFPWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF82</accession>
    <name>A0A423TF82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rab9A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006354</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001810">
        <property type="protein sequence ID" value="ROT75118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF82"/>
    <dbReference type="STRING" id="6689.A0A423TF82"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045335">
        <property type="term" value="C:phagocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF1">
        <property type="entry name" value="RE17845P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="78" mass="8852" checksum="2A50A2EFC31CA6B7" modified="2019-05-08" version="1">MSNNHRRQNSRGRSTVLKVVILGDGGVGKSCLMNRFVTDRFDEHSFHTIGVEFLNKEIELSGETYTLQASFPLLIGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH17</accession>
    <name>A0A423TH17_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_005676</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Toroid-shaped homodecamer, composed of two pentamers of five dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001735">
        <property type="protein sequence ID" value="ROT75773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH17"/>
    <dbReference type="STRING" id="6689.A0A423TH17"/>
    <dbReference type="OrthoDB" id="4966at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046148">
        <property type="term" value="P:pigment biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00642">
        <property type="entry name" value="GTP_cyclohydro1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.10:FF:000003">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000012">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006825">
        <property type="entry name" value="PRK09347.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006826">
        <property type="entry name" value="PRK09347.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="13">
        <location>
            <begin position="113"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT75773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="289" mass="32186" checksum="5C6A483926DAF288" modified="2019-05-08" version="1">MVPLDTPSQQSKKQQLIEEPGRPPMYKRGDEGRPGHTPANLRSETPSSALSLGTQEFAMPFVTGFARPTAASVADSNGSHKHDKNVENNKKNIKALEEHKLPKRKDTIPELAASYRSLLKDLGEDPSREGLLKTPERAAKAMLFFTKGYDQTVQDVMNDAVFEEDTEDMVIVKDIEMFSTCEHHLVPFWGKVSVGYLPNKKVMGLSKIARIVEVFSRRLQVQERLTKQIAQAIVEAVQPHGVAVVVEGTHMCMVMRGVQKVSAKTTTSSMLGAFRDDSKTREEFLSFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLV9</accession>
    <name>A0A423TLV9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001527">
        <property type="protein sequence ID" value="ROT77409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLV9"/>
    <dbReference type="OrthoDB" id="188042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48174">
        <property type="entry name" value="DUF946 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48174:SF5">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="511" mass="57376" checksum="A2A14F33B1508A15" modified="2019-05-08" version="1">MALEREEVARAWAPLVWLHSDEHFYPGDVQTFLSQVTPNPLSTAPPISVNEGSTTIILRPLPVGPASGDTFLMAHFDEECSNCHLPKFLYGKKPTPSHSPPVYAVIHSCHSSPVRTSRHVTKFYDDGLSGRFSSRLSEQDFAADAPQGTSDPAYERPSPPETLTTPQAASTAPSIEAHTRNAVSTSPAPTKSQAVTLSRQSINNNDNRTYYNNRNDNLTVDEGEEIGSDSDYTESRNNSNLHEQESTPRPLTSTMISVLNGTNQDVPKSRASGTLSDQSEGAQPYPLKHPEDDLVSTQRPVRTRKREINEESQVFTVTYWMFYPYNYGKDVCTINLGYYLGRMYKPPVNGTCFGEEVGMGKHVGDWEHVSIQFRGRVPLNMYVSSHNFGAYYQYNSYHQHFEYTGQDTRKGIPMSPEYPKIVRVESSHPVLYSALGSHGLWAAPGLHQYNSFPQLEDLTDEGTEWRTWLNLDVVDLRDRAALKQPHRQWLGYEGRWGNPKSKCHTLMLAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNP7</accession>
    <name>A0A423TNP7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein FAM107B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001442">
        <property type="protein sequence ID" value="ROT78058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNP7"/>
    <dbReference type="STRING" id="6689.A0A423TNP7"/>
    <dbReference type="OrthoDB" id="5963205at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009533">
        <property type="entry name" value="FAM107"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16768">
        <property type="entry name" value="DOWN REGULATED IN RENAL CARCINOMA 1/TU3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16768:SF5">
        <property type="entry name" value="FI14214P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06625">
        <property type="entry name" value="DUF1151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="35"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="23454" checksum="4CD5C9C3A3762B50" modified="2019-05-08" version="1">MPLKKYIRAPVEEVPSIKGKLAFFEQQGREVVYGAMIPEPDYSDDERETQPSSVSSMVARNNKVNTNSSSNNKEQEKGQHPASERLDGRGLIMPKKLVNPCLESSDKMNLHRELKFNQKMGVNVLNQKTELQKAMEKHNDKKVLREQQEKKQAEMTPFQKALDERAQKIEQMEKAEKGNVENEQTPSCEFQKIHAKVRAKMEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPL6</accession>
    <name>A0A423TPL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative proline-rich protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001388">
        <property type="protein sequence ID" value="ROT78388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPL6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="621" mass="67293" checksum="FA72840D3EE71557" modified="2019-05-08" version="1">MTKASDEVYPAERERDILYPKRSDEVYPAVKVSEEIEGLPAAVSLPDLSSSRGHAVVSLPDLSRSHDLTSSSRSHEGVSLPDLSSSRGHEGVSLPDLSSSRSHEGVSLPDLLEVTRASLSLTFRRVEVTRASLSPDLFVESKSRASLSLTFRRVEVTRASLSLTFRRVEVTRASLSLTFSSHGRLSPPDLSVESKSRGRLSLPDLSSSRSHEGVSLPDLSSSRGHGRLSLPDLRRVEVTRASLSLTFRRVEVTRASLSLPSSSRSHEGVSLPDLPSSRSHEGVSLPDLSSSRSHEGVSLPDLPSSRSHEASLSLTFRRVGHEGGLAGRVEVTRASLSLTFPSSRRSHEGVSLPDLRRVEVTRGVLSLTFRRVEVTRASLSLTFRRVEVTRASLSPDLPSSRSHEGVSLPDLSVESNRVNEGVSLPDLSSSRVTGVSLPDLSSSRGHGASLSLTFPSSRGHEGVSLPDLPSSRSHEGVSLPDLRRVEVTRASLSESRVTRASLSGRRSHEGVSLPDLSSSRVEVTRASLSLSRVESRGVFSLTFRLEVTGASLSLTSSSRSHEGVSLPDLSSSRSQRASLSLTFRRVEVTRASLSLTFRRVEVTRASLSLTFRRVVTRRLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQ71</accession>
    <name>A0A423TQ71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_002671</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001354">
        <property type="protein sequence ID" value="ROT78615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQ71"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="530"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="166"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT78615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="639" mass="70061" checksum="9F6C36149059DD62" modified="2019-05-08" version="1">MAANACTLSLAILPAMKPTHRNLGKSEKGRKDAELRSSIEFGNNVCDHEDMKLKISVDPEAADAAPEKRASSDAPQSPFERVLDEVGGEGRYQILLLFAYLLPLSFYSPFGSSSLLLMMTTPDHSCRVPGRPSHVSEEEWRNMTIPWEDGADGKLRLSQCHMYNMTYSDALRPGPSYAIDTSAITRCQHGWDYDKSRWRETSVSFFNLVCDDASSVTTIFSLAVAGNALGTLILSILSDRIGRRPVFFLTVLINFSFGLLNMLVPTKELFAAARFLTCLAFFSFYQMSYIIVVELSSGHLRGLTAALSFVVGTVGVCCVTFVAWVLAHWRSFGIACHAPSIFFFLYWWYLPESPRWLLSMGRVEECVAIMKKVAATNGRALPSNLRELLEEAKADEKKTASMRDLLRHSSLRKHLVITSICIVIFCVVHSGIMLNLHNMAGSELVNFLVLSVVEVPGNVVGGVSAHYFGRRLTLGLTLTVTAVFAGLATTAITDRWLLVTFCGLAKVFVTAAVLVVYMQIGELFPTALRSLSYGTTSVAGLSATVFVPALVSVGATDRKLPYYILCGLCIFGAAVSTLLPETLGRPLPQTVLQANHIGQDESFWSITTHWTRRKYVPIGEATGKEARNGTPSVAAETGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQD9</accession>
    <name>A0A423TQD9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PEST proteolytic signal-containing nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_002607</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in cell cycle regulation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with UHRF2/NIRF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001347">
        <property type="protein sequence ID" value="ROT78676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQD9"/>
    <dbReference type="STRING" id="6689.A0A423TQD9"/>
    <dbReference type="OrthoDB" id="10068198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029169">
        <property type="entry name" value="PCNP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16523">
        <property type="entry name" value="PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16523:SF6">
        <property type="entry name" value="PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15473">
        <property type="entry name" value="PCNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0832">Ubl conjugation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="73"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT78676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="220" mass="23392" checksum="59F20C45164597B9" modified="2019-05-08" version="1">MTTSPKVPQATFQTSARMPPRPCAHQVSMGVIKIRSSPSLLLPVVQVSVSAVQCPRNIPSPADFLQCLSPETSLVERSSATKRPAAEGDGGEEPKKKISFGLGKPLDKGTVGMPPSAKKPLGGISIKLGQSQQKNATQTGASALKPKVGAAASVFGSEDDDDVEEEMPPEAKMRMKNIGRDTPTSAGPNSFGKTRMGFCDSKKIYEKQLRDVQDKANKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TS42</accession>
    <name>A0A423TS42_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_001989</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001263">
        <property type="protein sequence ID" value="ROT79267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TS42"/>
    <dbReference type="STRING" id="6689.A0A423TS42"/>
    <dbReference type="OrthoDB" id="103349at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16029">
        <property type="entry name" value="4-S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047115">
        <property type="entry name" value="ARSB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342">
        <property type="entry name" value="ARYLSULFATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10342:SF274">
        <property type="entry name" value="ARYLSULFATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019309739" description="Sulfatase N-terminal domain-containing protein" evidence="8">
        <location>
            <begin position="21"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="9">
        <location>
            <begin position="26"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="9">
        <location>
            <begin position="167"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="338"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT79267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="538" mass="59754" checksum="E589712D0022101E" modified="2019-05-08" version="1">MTRNAEIYLWALVLLSSAAAASRGQPHIVLIVADDLGWNDVSWHNPQVVTPHLEDLARRVILEQSYVQPICTPTRSALLTGRYPFTLGRQHSVLKDNEPTGLTLNATLLPQSLKEVGYSTHAVGKPFLHVSHPYPPYSSPHPQHLFASYVEDLLTSRTRFVLPSRAAPLMVPEEYMKPYDHIQDLDRRTYLGMVTAMDEAVGRVVAALKSSGHYEDSVIVFTTDNGGPTKHGANNWPLRGYKTTLWEGGTRGAAFIHSPLLPNPGAVSHKMIHVTDWYQTLVGLAGGVAPGDTDGFDQWASLTSSAPSPRTQLIYNLDDTDKFKAGIRVGDMKLLINPGNAGWTPPPESEPTNQEPPHSQATKTETSSSKKYTPAKSYENSLYAEGDKSESWNHARRGRSSPGRKTMLQLNHELMERESTLVEGPYEDLQAVPQSKDQAGFGSDVAPNQDKSSISENFDGKDDLKLDYFFRNVDIQLYNIKDDPDERVDLSKIESDTVEDLLQTLLKEMPRYVAADIKPGDPGAHPKHWNNIWSPGWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT46</accession>
    <name>A0A423TT46_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Wilms tumor protein 1-interacting protein-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_001650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001215">
        <property type="protein sequence ID" value="ROT79629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT46"/>
    <dbReference type="STRING" id="6689.A0A423TT46"/>
    <dbReference type="OrthoDB" id="25414at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005912">
        <property type="term" value="C:adherens junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035331">
        <property type="term" value="P:negative regulation of hippo signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001666">
        <property type="term" value="P:response to hypoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047172">
        <property type="entry name" value="Ajuba-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24219">
        <property type="entry name" value="LIM DOMAIN-CONTAINING PROTEIN JUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24219:SF4">
        <property type="entry name" value="LIM DOMAIN-CONTAINING PROTEIN JUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="102"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="19470" checksum="645F2FA4F5E1109F" modified="2019-05-08" version="1" fragment="single">MAQSGVWSWQPAEIGAEMQEGRLGSARSVPGHPRLAVPPPPPSPIIMSTSLKLQHKFSGYTTRETVLEAGGGGKPWGSRGPQCPRWEQPAVSVLSLTLGRADTCPYIRVSFGLGTGETVRVVSMDKDFHVDCYVCESCGMQLTDEPDQRCYPLDGHLLCRNCHLHRLHAMGRTTSNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTP4</accession>
    <name>A0A423TTP4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001187">
        <property type="protein sequence ID" value="ROT79791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTP4"/>
    <dbReference type="OrthoDB" id="5867217at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019415588" description="Apple domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="50"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="344" mass="37763" checksum="1AF7E040C9530DD1" modified="2019-05-08" version="1">MLPFRVAPYLSLLLVLCGSALAQETEQPPTGLPPVFDIDFESTDAQLTGCPPDKVSFELVTGYVYSAPADMLDSQPGTLMLTDCIDMCRKNRSCMAVNYETGLCVLFSSNADMYPVLEEIMSWFYKIKDLFLCSLYSFYAYTRPHAHYTPTSSAMSVTGEAHTANHLRNLTYITPSPPPPPSSLPLSASLPPLSPLFLLTIRPYLSSSPILSPLLSVFTPSIPLYLSPSPPLSPLFPFFPPSRPFFPLFLIYLFPPSLLLPLPLPLIYLIISSLPLPPTPLIYLFISPSIPSLPSLSPHLPLISIPPFPPFSLPLPHLPLHPPSLPLPPPLIYLSTPPPTSLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTV5</accession>
    <name>A0A423TTV5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001178">
        <property type="protein sequence ID" value="ROT79875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTV5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="499" mass="53816" checksum="919D7045FE9A5961" modified="2019-05-08" version="1">MSCLGRFEEQPSSSVLSSRQPELPHTASAVCSPQNPVSLPFFQSPSAWYSSRLDLPFLLVGQITTGRSYREVTDSRDPSTVCSSLFPPLTSAILLVYLIPCQTFPGQIAWLLNACYAAGRPQPPLTSPSSLLPTFPPTSLPCPSPRLSPPRLPPLLPLSLPYTSLPPVPSSLPPYPAFSLPSSLPPFPCHPLTCLPTSLPSPSLASPSVTSLILFPSPTSPASRFTITTPPACCLRALPPLPSLLQVCLLASFLSSPAPGFSWPTLRWPAVLPLPSPLALLPSFTCVFLYLLLLIPSFTPLIVPSVVKFSMSLSPLPHARSWRSSSRLPAIFPRVFTRRRPPPLGGHANWAGGADRGRGLKAPQPKRERGEARGFIAHRNDSAHALVSHSPTRGRVSHRTFFSIKPVDVIRWRSREGEKKVGEGVDTPPRRTSGKGFRVGKGEIGAPWIRGGTYGAARNQQQLSSQGEETERIRGLCAATRGVILSLFVCAGVRDGNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWU9</accession>
    <name>A0A423TWU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000313</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001047">
        <property type="protein sequence ID" value="ROT80944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWU9"/>
    <dbReference type="OrthoDB" id="6496929at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032222">
        <property type="term" value="P:regulation of synaptic transmission, cholinergic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030431">
        <property type="term" value="P:sleep"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031424">
        <property type="entry name" value="QVR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050975">
        <property type="entry name" value="Sleep_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045860">
        <property type="entry name" value="Snake_toxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562">
        <property type="entry name" value="ATILLA, ISOFORM B-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33562:SF14">
        <property type="entry name" value="PROTEIN QUIVER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17064">
        <property type="entry name" value="QVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57302">
        <property type="entry name" value="Snake toxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="139" mass="15397" checksum="E31E243C93D886D1" modified="2019-05-08" version="1">MLGLGERRESCLGSAIRCYNCNSHLDPDCLNLDTPKAKDYLTDCGDEADGHRFTLCRKIEMAMDMDFGVAHPSETRVHRACGWEENDEDGKECYYKSGYNTRSWVCACKEDGCNSASLPGATFVVVPLAILSLALRGVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY32</accession>
    <name>A0A423TY32_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000986">
        <property type="protein sequence ID" value="ROT81381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY32"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="41950" checksum="14F86FBBE58CD3AB" modified="2019-05-08" version="1">MSPLTCLSQATVRNPAQALAHALTAWARAHTTQVSVPRESGQGASVATVEGLPPDLHPKRPPRDVRLQLCGLTKNFPRTTGLLSLPCAAPDGKRASLIPHECSRTLLTCLANTPFILPPIYALPALHSLLLTTLFLPYIYASPLPPPPPIYAFPLPPPPIQGLYKYLYRPCSYLRFPFSSLLPPNYALPPPPLYLRFPSPSSSYLRFPFSSLLPPNYALPLLLPYIYASPLPTPPPIYAFPLPPPPIYAFPSLPSFLLTTLSLLLPYIYAFPLPAPPPFSYLRSPPPPDSPPAAASCVCGAHAPECPGHATCSGFLSCLPVMVAGLEHSHLPLAKRTRPHLPSFATSANEDSSALVWRRPRAEASTQSVHLRKTKRGRSLPPPATTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYG8</accession>
    <name>A0A423TYG8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000976">
        <property type="protein sequence ID" value="ROT81422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TYG8"/>
    <dbReference type="OrthoDB" id="6356419at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009039">
        <property type="entry name" value="EAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005492">
        <property type="entry name" value="EPTP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15261">
        <property type="entry name" value="THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15261:SF4">
        <property type="entry name" value="THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03736">
        <property type="entry name" value="EPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50912">
        <property type="entry name" value="EAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1637" mass="176455" checksum="76147A569F76CDAA" modified="2019-05-08" version="1">MRPFQRIRTSAARDWAAFHFSNGKKTEYFLAVANEFSFDAAGRKNYNIDSIIYRYDEASEKFLPFQCIPTQGAYQWITYKGVHGEVLLGVVNGASGVAFYQYNGWRFVRINIPVSAPGVEWAWIGNLPNTLNEVLFMMSSSQANPRPASSYLEFTYQNPLGTYHNATAEWCSAYKTEMTNDGLSQLVLDVEQAPKTNESYTFTKPVHIDGSLTLPAGSAVSEVRDVDGLHFANLVTTCSTPGCIASTVDSLTANTVNGVSASYTGIALLNNTNEKLDLTFADVALAGGAVCSVTNIKAHDTAVIPMNELVTLHQDHTITADVTFNKVLADNMQVSGTVDGLTVDDSTLLLTYGTQTVNGLVTVDGVDTTLITTTNVNSRNFNDFIDSLIVNGTTDSFQGLLEVGDDLIAPNIDTLEDMKPLNPVDVEARALFHTKTSTQVVTGLHSVGNLEAVNGVWFDHLNGVLVPDDVFLKDETVTVSAPTTFDSITATSIQVTNAMNDVKQVGGSLEFLLLDKDATLTSKTFTDLTLEKDSTVAKLVAGYDLDYLAKGLHEKFLQDLNSGRAVNGSVIFEKELHVTSDKIHGVSIGKIRDTAIPLTATSLNPALTFEKPVPIAGAMTVSSTINGVAKDDYVLLDSDHTIVSPKTFVSDMECREDVTAGLVSGYNLAKFAKDVVLKKGPAQIIVQDLSMASADVNGDLNVAGQITIGGVNFNNVVALNATETVRGKKTFTNVEVTSSTSAGAVNVGDFGTVDGVVVKEIFFDDSLRKSVTSTQELVGRAMDTIIAQNAEGTDLAGFERKVVYKDDIETISGALTLEGSVSIASLNFESDFDGVSEAAYKSAWLLNEGPQTLTGSNSLANVDASAVNFQGIYVDGVHLGRLHTVTAKIDEQTTLNSTTFDQVESLSGITLDGTIQGWHLHEQALQSSSNHQRVTGKKRFTNPVHIKNSITVDENVIIPRAGGSPLVLEMSQFCDAFMQNGKVLGDLVVNGNAVFNKDLDISKSFNNEDVSTLASVFWLSDMDNTVSSVKQLDTAQVAGNAEVIMKGLINGEDFSTLASDVLKNKCTSQSFDLERILRTDKTQTITGAKTFPEVQVAGSVDLDGTLNGLDVKTNLVQYGKGADITAPKTFNQKLTVKGDLSMSSGSTVQGVDVSAFEESAVLHNTSGITKSIGGITTFKGLVLKTLEVGGTVDTVQVDSNTILLTSGAQSVAGLVTVSVPGQDKVVFVDQNLEVQDQMFNTIKLDKLYGDTVRVDGSKDTITAEVTFTASPTFSSITLENHLVNGYNLTDLILFLDGKHTLDNMGDHLEEAIQSSQDSNMVLEERPTDLWYFYETKLQETLYKLQPITLASPLGHRSIDAFVGLNWEDTSIQIYGPELGRKSLADELKDLCEEKEPLDVLAAFPPTSTISIPKAKVAAGLGNNHLAACGDSLVTFPYAAAPTYQQPFHLENGKDCLAVIDHGTTSEVICGTAQTGYRLLNYLGTKRAVKELNHDLQKASHLDALAGNHKAYVAVTHSISPVAAGGVDIFTVTDKSGSVEMKKMQTIKVPGALASNFGELAKYDVGLFVQTEHGVHVYVLKGMQFVHERMVKTVPARKPFSFPFFHTGQNTTFLLYAGNDLDGHLERNARVYEAVYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZG1</accession>
    <name>A0A423TZG1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000913">
        <property type="protein sequence ID" value="ROT81834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZG1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="41883" checksum="C7864C0BD04B4D4A" modified="2019-05-08" version="1">MKAAVVVPGAFVASHNRWPSRPSPESERSRLEPGEGSARGRGALDSRPIRAAGQSSSDTCSTAKPSLTSRTPFSCTRLPAPVWLSLDGLSTTLRCDNATSPATATTFPCHNDDDLPCHNDDHLPCHNDDTDDDFPATTTLPVTTTTTSPVTTTTTSLPTTTTSPNGDDFPATTTNLPCHDDPSPVTTTTTADDDPCHNDDDLPCHTTTTSPATTTTPCQRRPPPCTTTTTPLPQRRRPPCHNDDDLPCHNDDDLPCHTTTTQRRRPPLPQRRPPPLPQRRRTTSLNDDHPCTTPLPRRPPPLPPLSQRRRPPLPHDDDLPAKRRPPPLPQDDHLPCHDDPPCHNADHSPCHTTDERRRPAPPRPAPPLSPTNAAAATTSRRAGLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1R1</accession>
    <name>A0A423U1R1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative GTP-binding protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_024203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000795">
        <property type="protein sequence ID" value="ROT82631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1R1"/>
    <dbReference type="STRING" id="6689.A0A423U1R1"/>
    <dbReference type="OrthoDB" id="10268034at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000886">
        <property type="entry name" value="Putative GTP-binding protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="entry name" value="GTPase HflX, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3350.20">
        <property type="entry name" value="Tmem141 protein family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026788">
        <property type="entry name" value="Tmem141"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038259">
        <property type="entry name" value="Tmem141_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229:SF0">
        <property type="entry name" value="GTP-BINDING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="GTP-BINDING PROTEIN HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15110">
        <property type="entry name" value="TMEM141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="6">
        <location>
            <begin position="377"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT82631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="651" mass="72328" checksum="5CA9D910E89206AD" modified="2019-05-08" version="1">MLLPYNSPLSFVTISQQRSEIRTGSKGTRLGSRRFVGKMNNNTELINQYKDAFPAFGGYMECMSRTLLTGLSSFCLAFGGTYITQHLTSKYLPYGRKNHIIVSSLIACAVAYKVTSIRAEACQAGCHFKNAILNHTRSFTTSKSMLKKKKKATKRMTPPPEDTDEDFEKSILEDPDFSNLREGMEDLNIRKYLSGSVSHIGTIVLQPWVKWGPKMKRNTTAQLMLEEAATLVSTLPGVKVVAKEVVPVKSLDGKMIFGSGTLARLISEARTTRTAVSVFISVDMLKRSQIEELEAAFGMKVWDRYSVVLGIFQHNAHTREAKLQVALAELPYIRKRLPGERERMMIMEREKRIRNALNRLAGKRALIRRGRTRSNLPTVAVVGYTNSGKTSLIRSITGDESVEGKNSLFATLDVTAHGGRLPCGLEVAFIDTVGFIQDIPTELVASFRATLEDAVCADVVIHVRDASHPDYELQGITVHETLSSLPLSEETPVITVANKADLTLVKPKDEFGEHMLSATTGQGIPEFLDYLQEVVLKVTGRRSWRFSLPTGSPEIQWLRNVAGIVSEEMDPENLQPLGVAITCLLSLFSLPFRLCHLSSFLLICLSSTFSTVPFALLPLLRISSSVLSRHVQTAPSRYSLLLPLYLPSYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5Y0</accession>
    <name>A0A423U5Y0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_022682</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000591">
        <property type="protein sequence ID" value="ROT84106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5Y0"/>
    <dbReference type="STRING" id="6689.A0A423U5Y0"/>
    <dbReference type="OrthoDB" id="10037534at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15040">
        <property type="entry name" value="7tmB2_Adhesion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053066">
        <property type="entry name" value="ADGR_G7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47767">
        <property type="entry name" value="ADHESION G PROTEIN-COUPLED RECEPTOR G7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47767:SF1">
        <property type="entry name" value="ADHESION G PROTEIN-COUPLED RECEPTOR G7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01825">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00249">
        <property type="entry name" value="GPCRSECRETIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019134659" evidence="8">
        <location>
            <begin position="26"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="721"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="764"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="GAIN-B" evidence="9">
        <location>
            <begin position="456"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="10">
        <location>
            <begin position="613"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="866"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT84106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="962" mass="107594" checksum="45BB1DCA23DA3061" modified="2019-05-08" version="1">MMAFLHRLAVVRGVLLLVSSAAVWAQTKSVFPAEEPAPLDPLPSCNVAVLGDCLMPGPRPMSWEAAHRHCRSAGGFLLEREELGQFDHLWTSRYQTPLQKNLTMPVSVLSWPALNSSWPGGEASLEDLTLTGLTFHGRGTLNQVGLSARSLKKGLERTGREIQLYKRGEGYICIDNEEMLSGSNLLRCFANGREIKVKKAGKEENEQKVLQLFDLLGSTSELTSGCVIRSVRSTTKCFSETTVDSGIEERNLTWPSTAGGIIALPKELCITEEGEPVTRECLGSFLTGYYWGSPSSSCMGEPTNKTKQLWEINNNATVEKADIPTTLSSITQNGSTLQPVDIHFVATSFKTLSEETEKLDELDLEEIVQTINNVMEAKDETFEPVQKKLLSSSILYEAFEEMTFKVQLPEAKGDQKVNASRKLITVERFDLEMNSTIIGFESRKGGTVETTIEKGFRTDHADTDVAIILPENLTYTVATSHVSMRANIRFESKIQLAFAVFKNAKLFQDRDSFPNYTVSSPIIQATYRGEVVKNLEEPVTLIFKPPEYGRRNTKCVFWDFSKNGGRGGWSTQGCWKGKSRGNHDVCHCNHLTCFAQLMNYNSDDFDGNHALALDIITIIGCCLSIGGLLLVFTTFFLFKKWRRPLDNKILVNLSFSVFCSIVIFLAGINQTWNKILCRSIAVALHYFILASFGWMLVEAVHQYLKFVKVVGTYIPRFMWKASVSAWGVPVVPIIVVLVCDSSLYDNGDDSHPESNICWMSRDGFLYAFLPPLVLTMVINIIMFSLILYGAVCGRARVNSTMSERSLFISQLRMAICVFVLLGFTQERQEALGRLPLCHKQEPVVDGAFELQQRPRFYAVSRSLRQRDLQPRRRDPRHPSEADSTNDHQGNEHQIAGHDVDPPSLENKLHPVEMCSSTHYLPFLSSPFAVLSPPPPSLSLSSAFPLRFYGKDLSIICKSIHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U688</accession>
    <name>A0A423U688_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcified cuticle protein CP19.0 isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000581">
        <property type="protein sequence ID" value="ROT84223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U688"/>
    <dbReference type="OrthoDB" id="6369557at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019342595" evidence="2">
        <location>
            <begin position="16"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="171" mass="17855" checksum="8532BA6364BF522A" modified="2019-05-08" version="1">MLRKVFLAVLGVCSAGPFTGYTPEVQAERARFFQSFSAAQAAAAPQQAYYHHAAAPQQALYHHAAPVQPKWTGPVAATVPAGVDGTITPSATPTSAYQAQLRATVGAHSFHHAAPVQPKWTGPVAATVPAGLPGSAPQVADTPKSPPPSSSSSAPTTGRRQLRRPPSRHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7Y7</accession>
    <name>A0A423U7Y7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative basement membrane-specific heparan sulfate proteoglycan core protein isoform X6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_022006</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000496">
        <property type="protein sequence ID" value="ROT84796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7Y7"/>
    <dbReference type="STRING" id="6689.A0A423U7Y7"/>
    <dbReference type="OrthoDB" id="10047962at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005041">
        <property type="term" value="F:low-density lipoprotein particle receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1220.10">
        <property type="entry name" value="EGF-type module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.75.10">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF14">
        <property type="entry name" value="MEGALIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00095">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00217">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="WAP" evidence="11">
        <location>
            <begin position="73"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="522"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="537"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="675"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="715"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="739"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="751"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="779"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="810"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="828"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="861"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT84796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="885" mass="97457" checksum="214388742C04EBF0" modified="2019-05-08" version="1">MGRKQSLKRVFPAIGRGEDEAAGRAKRGGGSEGGGDFVTEPDVGSDGWGPEGWWDEAVVDENFNPRGYRAANWPFVNGRCPSRSELSGQTPCDFECREDYHCPEMKLCCSNDCGRVCVIPDTSGPTRCGCSVTFFTDLNEYYSSPSDIAKVSHFVWNVLQGSLSPALEPHLFFGSLENRDWLGADVQDDLAIITDANSTFMQSYVDYFPEIFDHFIAINIGDVDQAGKLAAAANHLIEVISLDDLTRIVQEARYDIGGERASGFGLLSRPETRAKGTVIDSPLSATKESANVLNLIQFRRLTRPGGKPGPGAKPARHRNGSLAQEGDRIFPVIIEKNSTQKGQPDESSNKKTVVTSTPCTKRPYPECDGYLSLKDKEDCEKHKAKKNCPEPEAGKTNKKLAVLDEGPKRYLYRTLDYTGHCKAGLFRCSGIPNICLYGELLCNGESNCIFGEDEDEDFCSKRECLVTEFRCDSGQCINKHQECDGKTDCWDGTDEHCASDSDCSTPRTHYCGGACINPLFMCDNILDCPNGEDERDCNCTGFKCNSGECIGEYQLCNGKGDCNDQSDESSETCSGFVCQEGHSKCDSGACIPDYQTVQMDLMNTTVQIIHVPHTNFGVARATVFTPPTYATVGKNAQTDRKDESVCKEVTCPSHRSYKCDSGECIYTSSYRNPRCDGDKDCRDGSDEMNCEDVLCPANEPFRCGSGECIYDSWVCDHYRDCMDGSDERGCDCWYNQISCDSGRCISANSQCNGIRDCLSGNDENECDNFTCPYNRPFKCGSDVCLSDSIFCNEEADCPGDVHEVCLSRECEEYEYQCASGECVSGNRCDGYIDCRDRSDEANCEDFVCPEERPFKCGSAVCDGFYDCSDGEDEQNCITSTTVAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U802</accession>
    <name>A0A423U802_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_021982</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000492">
        <property type="protein sequence ID" value="ROT84819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U802"/>
    <dbReference type="STRING" id="6689.A0A423U802"/>
    <dbReference type="OrthoDB" id="6372332at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="79"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="470"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="470"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="485"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="500" mass="53651" checksum="854644A864ECD30F" modified="2019-05-08" version="1">MRPSLPLYPFSSIYMPRLNLAPSSSTHAPAYSYPHPPSPSTSPASLPTPSTSPVSLPLSLLYPAAFTASLPSPPASLHLLRIPQPSPPSPRRLPSTLQASPSPPSTSSPPPPPPQHPSALSPPPSTSSASLTPPLHLPSIPNHSLSPLPSPTAPQQRKAAVPEVEIKLATSRTQARGRVQFNHKAGKYEPLGDDPSLIDLLTLPSRTPPALATETHDFDVHEDLRELYGDLVSAEELDRLDAQPNCFNFSERVSQTLRPQTKSPRVSESDRGPPLPLPETPSTPSPPPRRSTFVENEVNLQGLLPAAKVVERMANQNIQDEVVQEGDWEAESEGMVCLYTLKNPGIVERLVPVPRGVTSIHLHPTRPSVLVAGRTDGEVMVVSFRDAGPPSVLTSSASMGKHLLPVGQVSPESEVHSSFSYFLRLSELYVLAIVVLGFVADGLVDIGNKGGLPVLPSALRRDRLLRGVPVAADSRPDADSAPGEARPEPRAAADHRQRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8K8</accession>
    <name>A0A423U8K8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000452">
        <property type="protein sequence ID" value="ROT85042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8K8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="45095" checksum="BBBF922283ECB9B5" modified="2019-05-08" version="1">MMAMFGVSRRACGCGDVESPPDVSNPDSSWPTERAITERRFRRQYAKLRNLFVSAAETKPGRGRAPSLPLTVGHEKRKPGLQLGITPVTSASRPRKKAAQLFSSPPLCVSPLLSHILSLFLSSLPHFLSFFLLLSPSLFYNYSLRPFPPTPFSLPTLFLPYLILFIHLLPFLLFLSNPLTFLFPSPFPSPPPLLFFLFYVTPFHSSPLFLPSYISPLFSYLSYTSFLTLSLLPFSFPSSFFALTLFFSYSSPLQHIQPPYLFLSYSFLSPPTLFLAPPQSLRLPSPILQHSPGLPLLPRPLRLPSLIPPTLSRASTLLISPYTPSPPPNPSVSLPLSLQLFPVPLPLLNLSSSIPLHQPFRLPSPIPQHFPIPLPSLTPSPSLPFLPNPSVSLPHPSNTFPCLYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAR9</accession>
    <name>A0A423UAR9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000188">
        <property type="protein sequence ID" value="ROT85785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1260"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1284" mass="139402" checksum="A51C55A6FE0116A8" modified="2019-05-08" version="1">MARFPREGATRQRRDPGPALTLRPNSPSPASLSSLSLPPPLFLFGSFSSPFPFPLLLSFLTPLAAPILPFSLFPFPSPFLIPPPLPSSLSPPFFPSPPPSYFSLPSLSAHPLLPLPPPSPFPLPPSPPPRYNSPPFLVSSLFSLASSLSPPHSYSLPPFLFLLFLLPSFSLPPFPLPPFFPFFFSPASPSPPPYPSPLLPPLFSPPFFPALLPPSLPSLPLFSPPLFPPPPPSLPPLFPFSFPLPFLFPPLFLPLPSSPPFPQSTPFFPPFSFLLFPPFFGFPPFFCPPLPSFPSLFLPFFPFPSSLFPLFPFPPHLSLPLFPPPLSPPPFFPSFPPLSLTSLFLFFPCSSPPFFPLPPSFFPFFLFPFPSLPLFPLPSFPLPLPSLHFSPSPPSPPPPLSFPPLSPFISPFLLFGSPFPLPSLPPLPFFPLPFLPPSPPSPLPFPPSSPPLFPFPLLPFFSSPPPFLPSTLLFPLRPPSFLYLPPPPSSLPPSFFFLLSPPPSLSPFLPSPPSPSFLPFFFSPFFFPPPLFPSPPHPPSTSSSCSPPSPLFVFTFLPFRPFLLSPPSPAFSPPPLSLSIPLPFFPSPPLPSLFPLPLLLSPPSFPPPSSPPLPPLLPLLLSYSLTSSLLFSPLFPFPFSPLPPFPPPLPFPPFPPTFPLHSPPCSLLPHFFPPFFPLLLPVPSFSPSFLFPPPPLSLSSSLLPLSLSLLPPPFLDLPFPPCLPFLPPPDSLLPSLLLPFPSPLPPLPIPLPLLLPFPFPPLHSLPSSPPPFLPLFLSFIPLSPFPFPPFSPPSLPLSFLPSFFLPPPLPSSTLVALFSPSFAPRPFPFPSSFLPPSSPLFPFRPSPRLYAFLPSLPSSPPPPFSHPLLPHSFPPSSLLSPLLPSFPPSLPPPPLSPLLSSSTPPPPFSPFPFFPLLLPPLPSSSLPSPLPGGLPPLPHLAPVPIHFPPSFFPLPPFPFPPPCPFFPFPFPPPQLPLPFLSLHLSPFPPSCPFPFPFLSPPPPFSPPFASLSLPFHPSFPFLSIPPPPLYSFLPSPSLLFPPPIPFLYSSPSCSPFPLVLSPPFFFSLPPLFPPPPPPSLFLFLSLPPPPSPLPLPFFPSLSFLLLPPSFLLFLSPPSSPPPPSAPFSPPLLFPLSLPLLSSCPTSFPPPLPPPPSFSSLPLPPSTLPPPPLPFSFPSPFLPFPYSPLLPTFFLPFPLSSPSLPPPLFLFCCPTFSPPPFPSSPRSPFPPPLLFCPFLSFPFSPSSVPFPLPFSPFTLSSSQHHGLRSTAWPSKRPSARPPETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQK2</accession>
    <name>A0A3R7LQK2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004003">
        <property type="protein sequence ID" value="ROT61759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQK2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="43721" checksum="F94FAC1718974F14" modified="2019-04-10" version="1">MPPTPPNPQVSTCPPTPTPKYLHAPTHPNPKYLHAPTPKYTCPHSTPTPSIYMPPPTHPQVSTSPPPHPNPKYLHAPPHPNPKYLHAPPPHPTPKYLHAPHPTHPPSIYMPHPTQPKYLHAPNPVSTCPTPPPPSIYMPPTHPTPKYLHTPQPYLHAPHIYMPPTHPTPSIYMPPPTHNPPTYLHAPHPTPTQVSTCPTTPPSIYMPPTPSSYMPPLHPNPQVSTCHPPTRPPSIYMPPPQPPSIYMPPPTPTPIYMPPPHPDPQVSTCPHPPNPPPVSTCPPPHPTPVSTCLHPTPTPKYLHAPTPPQVSTCPHPTPTPKYLHAPPTPKYLHAPPYPNPKYRIYMPPPPQPPSIYMPHPPTPSIYMPPTHPNPQVSTCPHPTPTPKYLHAPPHPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRK7</accession>
    <name>A0A3R7LRK7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004415">
        <property type="protein sequence ID" value="ROT61039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRK7"/>
    <dbReference type="STRING" id="6689.A0A3R7LRK7"/>
    <dbReference type="OrthoDB" id="6381864at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="1">
        <location>
            <begin position="192"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="393" mass="44251" checksum="B9863D67C75790BE" modified="2019-04-10" version="1">MRPRSPVEGRNRGLQPSTSSVVPARVLRHTIAIACTLGTSFAHLFPYFVGRKWRRLDAESGGGRRRPRDELDSFPLVDAAVDTTLDSDELLSSVAAKLALRKVPGSKGFTWRHKVNVPKIEEFRSDPGVRGYPPFCRLATYEEVDSNVLAGGQGVPWDSLIMGMVKVSSSCDYWSTNLVLRHHLIAEVMRDQFNQLTHIHFSHLEEISIDELLWKFRGRLAFWTYNPTKKARFGLKVYMLYASIGLAAGYTGKDLGDMPSSTKAVLHLMEYGGFLDKGYQLFVDNWYTSPTLFHLLQSRRTNAVGTARLNRKFMPKDLSVSWRDDVDYPSSTTGLLALVWKDSNNVTMLSNVHTAAMEGEKPLVVKDYDVGMKGVDVGDQMMNYYPTPCQSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRZ1</accession>
    <name>A0A3R7LRZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003551">
        <property type="protein sequence ID" value="ROT62793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRZ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="422" mass="46667" checksum="27D6F13D3E3E6942" modified="2019-04-10" version="1" fragment="single">KVKWKTPPKPLSARPIRSASSSVSGKNCGCLRSSLSSPLPLPLPFSPLLCRLSPFFHLLFPLFSLSPSLRLFNLLLHFLRLFPLFSPRPLFVSFLLSVSVLPLSLLSVVSFFSLVTLLSLSLSLYLSLLHSLSSSLCSPLLFPCSPLPPSLPPPSSPLSHSPHSPLLPLLPPFLLPFLTKQKRKGKSSCSVTRIPPLARNPPFPLWPGPKTPLWPENPLWPENPLAGPKPPWPAPKTPFGPNTPLWPENPLWKTPFGPKTPRKHPFGPKNPFCPKPPFGPKPPFLPPFGPKNPPLARKRKPPFGRKPPFGPENPFARKHPFGPKTPLARIPPFGKPPFGPKINPPLARKPPLARNPLWPKTPLWPENPLCPKTPFGPLAPPFARKPPLETPLWPENPPLARIPPPPWRVRGLKSGGIAYFVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LU04</accession>
    <name>A0A3R7LU04_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="6">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019257</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01003531">
        <property type="protein sequence ID" value="ROT62866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LU04"/>
    <dbReference type="STRING" id="6689.A0A3R7LU04"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000003">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000079">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000002">
        <property type="entry name" value="E3 ubiquitin-protein ligase HECW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024928">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF429">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SU(DX)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001569">
        <property type="entry name" value="E3_ub_ligase_SMURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="10">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="11">
        <location>
            <begin position="402"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="11">
        <location>
            <begin position="434"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="12">
        <location>
            <begin position="528"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="207"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="358"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7 8">
        <location>
            <position position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001569-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="862" mass="95763" checksum="54CABD2F720B9852" modified="2019-04-10" version="1">MSEAANASHLHQLSVTAVSGELSALSSLFNKPSAYVELLVDGVHQKKTQHVKHNTHPKWHETFTVLVTKDSVLVFRVSDHHTLVRDSVIGEATLKLADVVAANDGKKSSTHTLPLTQPTNCVVPATSQPPTITVTLDGLNILTQGGARQREVNYNLPTVVNVSGGNVSGSNTVTVRVGGKTPPPVPPPPKLIQSDAHSGAALPAIMSASGSQSNSGTTITHTSHTSATHSPIPSLPSINSDGQAASSHPSARARKSVGNGSAVVVLGGESPTDSSGNQNGRPNGAESIAPPVPGNVSPQANHQPNPPQVASNATNGKLPTNGTPQHSASSAAAPKPPGLAPRPANRHHRAHKNKRNSDGSNTPGSGNSNGSSSGAPASAGNISSSSSGSNSAQPATVGVQEEPLPHGWEMRHDQYGRRYYVDHTTRSTTWERPKPLPAGWEARRDPRGRVYYVDHNTRTTTWQRPTVEHISANRGQYGIPVVYERSFRWKLGQFRYLCQSNTVAGHIKISVTRQTLFEDSFHQVMRLPAFELRRRLFIIFRGEEGLDYGGIAREWFFQLSHEVLNPMYCLFEYANKNNYSLQINPASEVNPDHLTYFKFIGRFIAMALYHGKFIYSGFTMPFYKRMLNKKLTMKDLESIDPEFYNSLVWIRDNNIEECCLEMTFCTDFEVLGKITEVELKPGGKDIQVTEENKEEYIDLMMQWRLTRGQEAQTRHFLEGFSEVVPLEWLKYFDERELELLLCGMQEIDICDWQKHTIYRHYNRSSKQIMWFWQFVREIDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQKFCIEKVGKETWLPRSHTCFNRLDLPPYKSYEQLVEKLTFAIEETEGFGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXS3</accession>
    <name>A0A3R7LXS3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_015970</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an essential role in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002998">
        <property type="protein sequence ID" value="ROT66039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXS3"/>
    <dbReference type="STRING" id="6689.A0A3R7LXS3"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF177">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018381556" description="Transmembrane 9 superfamily member" evidence="8">
        <location>
            <begin position="37"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT66039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="334" mass="38965" checksum="95391D354BAF6AFF" modified="2019-04-10" version="1">MALSKADTSGKEPELPALRERRLILLFLLYFTAIEATSFQDGDEVILYVNKVGPYFNPHETYHYYQLPVCRPKIIEHKSLTLGEVLDGDRMAKSDIRIKFKENMQNRKLCDLVLSEEEVQYLREAIEEHYYYEFVVDDIPVRDFIGHLEESGFVPHTHKVYLWTHQHFNIYYNDNKIIYVNATKEHAPISLDDVEPPLNIQPTYSVTWIPTKIAHADRGRLIQDNSFFPRSLEIHWLSIINSMVLVFLLIGFVVIILTRVLRNDFARYNIDEEGRDDIEMSMVGKSSTPMYSGSHSTRACFHPFWVLDVSSWQWQWGSSAWLCWACSMSTVTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYQ9</accession>
    <name>A0A3R7LYQ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_019590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003623">
        <property type="protein sequence ID" value="ROT62570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYQ9"/>
    <dbReference type="STRING" id="6689.A0A3R7LYQ9"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03177">
        <property type="entry name" value="GST_C_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF9">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="91"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT62570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="227" mass="25139" checksum="33AB36D25558C678" modified="2019-04-10" version="1">MLLTAKAVGVELLKLLDLMAGSRMKPEFVAINPQHCVPTMVDGDSLSGVRRAGRVTLFPTCSYEVLQETVVRAICSYLATQYGKIAPLSFRPEDARLVDRLMYFDMGTLYFRFRRYVVNEGQPEKLENCTKPGWLDGYLDGHEWAVGNSVTVADFVLVATVSTFEAAGIDLSKHKNVTAWLARCNTWPLRGDETPRARGLLRQDGSGRGKLGKQLSVSESPSHAEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZE3</accession>
    <name>A0A3R7LZE3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative zinc transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_019022</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003491">
        <property type="protein sequence ID" value="ROT63104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZE3"/>
    <dbReference type="STRING" id="6689.A0A3R7LZE3"/>
    <dbReference type="OrthoDB" id="29444at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010312">
        <property type="term" value="P:detoxification of zinc ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF9">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="16"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="406"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="490" mass="54318" checksum="28498DFF212AEB48" modified="2019-04-10" version="1">MAEKGELLRRIPSVKLWLVLTFTLAYTVVLLVADYTTHSLTLRVEVYHALYNFFSLIGCLLTMKLCSRPQSLHNTFGWARLEVLSMLTTLLFLSALCFSVAVEAIQTAVHAGHQDAMHHPLQVLMLGIVGLAINGVVFCLIGGYTHHQGCFLEMRPSGGVWVGRQVTQEAVQAGRRTLSSRSLKAGAAKPSRISQGVLEVLRDICGVLLVMVCAAVVYWDDGGTIALYIDPGLAVTSAALLMWFSYPYGKECCHILLQTIPGHIDVEEFQARFLQEFPAIVNVHHLHIWTFTPENVVATAHVVFSSPRVYLNMKAALTHFFHEEGISKVTLQPEYLEMGPDEALDSTLPTKGQVCLLRCENEHCYEKECCHECCHQELTSVNTTRARVVTTNAKAVEEGVTTKTRCTVTDAPSKRVTGKAGEGEPLEKDRSAIQPKSLEEIDDVEQPEEKIPFLKSKRLSSDDGNESGSPPQREENVMQKDALEHESESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1D7</accession>
    <name>A0A3R7M1D7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_012623</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1D7"/>
    <dbReference type="STRING" id="6689.A0A3R7M1D7"/>
    <dbReference type="OrthoDB" id="2105199at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="9 11" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="68"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="203" mass="22943" checksum="503DAE0B2495A625" modified="2019-04-10" version="1">MSSWNNPVQDTVLPSTNPYGNYTVVDTVPESMLHMVHAHWYQFPPMNPLWYGLLGFWMTIMGTLSVAGNFVVIWVFMNTKSLRTPANLVVNLAISDFFMMLTMTPPLLVNAYWGTWILGAFFCEVYAFLGSFFGCVSIWSMVFITADRYNVIVKGVSAEPLTSGGMMRIAGTWLFTLAWCLPPFFGWNRYVPEVTCLPVVLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M575</accession>
    <name>A0A3R7M575_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_009349</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide. Man(5)GlcNAc(2)-PP-dolichol is a substrate for ALG3, the following enzyme in the biosynthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="4 14"/>
    <dbReference type="EMBL" id="QCYY01002184">
        <property type="protein sequence ID" value="ROT72277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M575"/>
    <dbReference type="STRING" id="6689.A0A3R7M575"/>
    <dbReference type="OrthoDB" id="2276068at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 18" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="7 14 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018564143" description="GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase" evidence="15">
        <location>
            <begin position="25"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="17">
        <location>
            <begin position="12"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="16">
        <location>
            <begin position="223"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT72277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="424" mass="47641" checksum="58F586305569609A" modified="2019-04-10" version="1">MSLAVRAWSLGITLILQLYQHVKCYVYTGDIDVTPQEILQKAQQRFGVVLPRPVEFIFLQSRTVVEARHYSFLTLLMQSVGSLMLGGEALLKFRPDVYFDTMGYAFTYPIFRYVGGCVVASYTHYPTISTDMLGQVANRVEAHNNRGFIARNTIFSAMKLGYYHLFALMYALVGRCAHLVMVNSTWTHGHITALWGQAHHTHIIYPPCDTEHFKSLSLIPDASKKLKTIVSIGQFRPEKDHSLQLRSFQKLCEILDPADQEKVRLVLIGGCRNNEDQQRVDDLKTLASDLGVADKLVWKLNAPFSELLEAVQTGTIGLHTMWNEHFGICVVECMAGGLIMVAHDSGGPKMDILLDYEGQKTGYTASETETYAKVMKEILEASDAERETIRTAARSSVDRFSDEQFETSFIGASEFIFSSTGIHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6Y3</accession>
    <name>A0A3R7M6Y3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002634">
        <property type="protein sequence ID" value="ROT68801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6Y3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="422" mass="46177" checksum="F731B60242F26F84" modified="2019-04-10" version="1">MLEYPCHGYYQPSISICLMWPLDYPLPNPLLTPHPPKLPTTLSRLPIPSDPPHLHTPHPPNPSPLPPSPFPGLTHTHPTLSPYPPLTPFPDPTPTHTPHLPIHPDCGYERSAPERSIAPGFFLPLSSCPYPFPFFDLLYSPFLSLLISSVLSLLPLPSYPLPVFPHYAFLISSLLILLPSYCPIAPPPFFSSLPSLLLSLSLFPCPPPPNPFSFPIPLPSSPTHPPFPFSSNPLPSSSLPPPPIPFSFPIPSPSPTPPFPPPSHPFLIPYPPPLLTPPFPPPSHPFLFPYPLPPPQHHPSIPPYPLPPPYTTSLSPSPPIPFSFPIPLPSSQHHPPLPSLQPFLFPYPPPSSSAPPSPPPPSHPFLIPYPPPVLPNNTLPPLPPIPFPFPIPLPLHHPPSHPPSSLTQSTRWNLDAAEIFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAH1</accession>
    <name>A0A3R7MAH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative dual specificity protein kinase TTK isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_003932</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001527">
        <property type="protein sequence ID" value="ROT77407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAH1"/>
    <dbReference type="STRING" id="6689.A0A3R7MAH1"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="503"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="32"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="735"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="280"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="390"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="461"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="735"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT77407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="763" mass="84307" checksum="5327CF54CD5541A6" modified="2019-04-10" version="1">MEEEEKWDEGPTVEDVLSSVLKSKSKFGKIKLSLPPLPPRRTTFHVKEPSRDDFPRTKTEELQSLLHGKKTNSDEGSSAQVNIGELKPKEISGRVSPQNRERLNPNNFGRHHLSMSSSKILRSVSTPEMRDKSSFKAAVGVTAAETVKPAASRQMNFSEMPQSKHANKENTNPILSCHTLEGKCSNTLESVFKDMQNTKFQSLLADDFNLGGAKAAKEYSFEVSNTGETVKALLERDIFCDSKPVVSQKDPLKSDHFLKSIDTKVVKNSDQLNLSQKSLFPKCSQTPNQKTVPQTTVPLSSSHSKVSPDSASGRGTQSSAPSQKAFLTSSVTATPRPVSTTRFSELSQKSEAQQNKEVPVVAHRNVSSEEISARAGLAKDSADLAHAKHSSAVPQQSVVSQVHHNAAQSALSSHSSTADEYRQPKISKVPQTNQPAPQGTTTKNKSPSATGEMKFKETPVINRTQSRQFQTPSGQMLRAMPPTPPTKQKLQQMDHIVVNDQEYLKLGLVGRGGSSKVYEVLDLETRKVKAIKLVELEGVDEATLHSYKNEIDILNRLQWSDKVIQLYDYELTDIYLKLVMEKGNRDLASILNSARGKNAKPISPFTIQHYWQGMLLAVQAIHQEGIIHSDLKPANFLLVNETVKLIDFGIASSIQQDMTSVIKDSQAGTFNYMSPESLMDVHSGPIINGRSGDRPTIKRKRPSISELLEHPYLTAKPGEGETPQKEPHLKSMLQQLSQLTPNSLSKITSMMQQMQSSDSKPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBI0</accession>
    <name>A0A3R7MBI0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002192">
        <property type="protein sequence ID" value="ROT72215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBI0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018649765" evidence="2">
        <location>
            <begin position="20"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="12210" checksum="6CBD0743BC4EEE68" modified="2019-04-10" version="1">MKSILLLYSLLGLMAAAQALPNGANATTTTETPTTTEIPTTETPTDPPTTEPPPETTTTPTPAPTEPPTTPPPTEPPTTEPPTEPPTEAPTTLPPPTTTAKPCPTPDGRHFDAPSFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD88</accession>
    <name>A0A3R7MD88_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pax3/7-1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_002545</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paired homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001341">
        <property type="protein sequence ID" value="ROT78744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD88"/>
    <dbReference type="STRING" id="6689.A0A3R7MD88"/>
    <dbReference type="OrthoDB" id="3225452at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007365">
        <property type="term" value="P:periodic partitioning"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000031">
        <property type="entry name" value="Paired box protein Pax-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043182">
        <property type="entry name" value="PAIRED_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001523">
        <property type="entry name" value="Paired_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043565">
        <property type="entry name" value="PAX_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45636:SF49">
        <property type="entry name" value="PAIRED BOX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45636">
        <property type="entry name" value="PAIRED BOX PROTEIN PAX-6-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00292">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00027">
        <property type="entry name" value="PAIREDBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00351">
        <property type="entry name" value="PAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00034">
        <property type="entry name" value="PAIRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51057">
        <property type="entry name" value="PAIRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0563">Paired box</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Paired" evidence="10">
        <location>
            <begin position="73"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT78744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="177" mass="19455" checksum="E469E5C6C6AB27B8" modified="2019-04-10" version="1" fragment="single">MAAGPFRDRQGRATPFSPLALSLPLERPGLRGGKRRAWRGHSGFARTTGCLGRRCWLTGGGDGRRHLEIGQVGQGRVNQLGGVFINGRPLPNHIRLKIVEMAAAGVRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPKVTTPDVEKKIDDYKKENPGVFSWEIRDRLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MH82</accession>
    <name>A0A3R7MH82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative rho GTPase-activating protein 12-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_020438</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004004">
        <property type="protein sequence ID" value="ROT61754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MH82"/>
    <dbReference type="STRING" id="6689.A0A3R7MH82"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="344"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="525" mass="59888" checksum="851D8519A3C27EE1" modified="2019-04-10" version="1">MFISHDEEDSILEDKPLTSESGEASARALGTEDDASGQGARRFFAPSPRCLSPDNGSGTHSDREESTFSDDTEGSTSTLPCLGIGSDHYKELKRSLDSEKWLATNNDDGKIYYYEENGSRSQWKLPELDSFDEFDIRDGQQTSTLESQRVSLVTENLAELSKNIVKEGFLQRTFILKEGKKVRKNWTSSYARYIVSSFNSGSQGLIHFSKTKDDDKKAEIFDFIPPCSLDLSNDKKTSRQQVIALRNGHDTEVLLQFEDRDIENEWHKVLVDHDGMQQNMASVAEKEEKKGKKGSEKMKRAASIEQLAPDSKGITDKLLNFIKRRPLKETLEKKGIYKEAVFGSTLSELHLQDKTAIPIFVLQCINHIEKSVENLRTDGLYRISGNAAQIQKIRYEVAQRNYTILSREKEVHNLSGALKLFFRELKEPLIPFANYQDFIQATGSEYRKKNQQVEKLTKAVRQLPVENYDTMRVLLQHLLRVSEYESENRMSISNLAIVFGPCLLWPKITNAQDLMTDMRNEVEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIE2</accession>
    <name>A0A3R7MIE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019697</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003673">
        <property type="protein sequence ID" value="ROT62472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIE2"/>
    <dbReference type="OrthoDB" id="6354698at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="48576" checksum="C2F46799A87680DF" modified="2019-04-10" version="1">MQAHPANSRQPPHAAQRRPADPPRFELPISHPRKGFDPTTGLLLTTSMTLVPLRDLRSALTQLPDTTRHQLCLSSPASLVLWSSHPPLNTHPNPPPPPTALDDGKRSACVLVLLALLAGVAGRVAGVPATSSACSCGNHPAPAPGLCSGVALLHGTASDIRRSVLRELCLRVHQHVHLKTPQRSASNPKQQPKRTEQAAALNLHRDSFSDQVRWEAGEASDVINTANWFVDAEVPLSNGYTWYEHGLPLWPLLDQALTQKETVLAKKKKLNWPNYAIATPLYVAPLEASNSRDLAISVRKLFAGDTARPQQQSQNTFANSNKFQSTVLDFIKDHFQDQFGYTRSDIGQTFGETERWIQPLVKQSLRPMLESFMKRQKTRAPKSSDIATCPDEVYLFFLQKPCPTASTCQVILDIQQELRVTNCVNTDVVVGYTTARSASHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNN0</accession>
    <name>A0A3R7MNN0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative p63-like transcription factor isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_015731</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the p53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002965">
        <property type="protein sequence ID" value="ROT66269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNN0"/>
    <dbReference type="OrthoDB" id="5915660at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012346">
        <property type="entry name" value="p53/RUNT-type_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011615">
        <property type="entry name" value="p53_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002117">
        <property type="entry name" value="p53_tumour_suppressor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11447">
        <property type="entry name" value="CELLULAR TUMOR ANTIGEN P53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11447:SF16">
        <property type="entry name" value="P53 PROTEIN LONG FORM VARIANT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00870">
        <property type="entry name" value="P53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="p53 DNA-binding" evidence="14">
        <location>
            <begin position="246"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="125"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="405"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="12">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602117-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR602117-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT66269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="507" mass="56094" checksum="FA8076FA34071D10" modified="2019-04-10" version="1">MFANNDEKIVWLTPGKGKALSSSSCRVLTFSFIAFQQENTPNDWVGNEILSLIYGNHPYTPQNTPQPTPQAIQSQPLCHQVNQPLAQTPSGFPAPSHPQTSSAPSAGTNALQVHMQYVAAEVPQQQPYSGQNQPSFRPQFPGQPLTNGGTMNSLAQPPSGNSCSPAQPVSRPGGSQALFTPFSVGGKRPSDYSEQYGAPLKCTATSPLFPQDPQGPETAREPPVAQLSQCLESTRGPPVAQFPQRNRIEGSHGFKVTFPGNSPKFIVSNIGERRHINTLMNNYITTIIHHSAGPRAWLRFFIVFSRDSETAQPVLPCRNHQNENHPYHMLEVSAGNDEARWDYDFHPSVMVRPAPASAGVYNVQLRFLCRNSCLTRKDLMLICQLERDGVVEGREVLDVKVSACPRRDVPKSSGNPPPPKMPREDRNQGSHQEGCLGLGESMDTVPVPALPASANVLEQAFSQAQDFGIHSARLHYIGQRFRELHPEEYEDVERQFNDLWDSRMQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MRE2</accession>
    <name>A0A3R7MRE2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000613">
        <property type="protein sequence ID" value="ROT83975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MRE2"/>
    <dbReference type="STRING" id="6689.A0A3R7MRE2"/>
    <dbReference type="OrthoDB" id="6372777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="27724" checksum="0DB4BCC21F07A118" modified="2019-04-10" version="1">MTAATVINCLSQLFSIFGMPAYVHSDRGSSFMGKEVQDFLVSKGIGCSRTTAYNPQGNGQVERFNGSIWRTITAALKSRGLPTQYWQTVLPDALHSIRSLLCTATNATPHERLFNYARRSSTGTAIPSWLCEPGPVLLKRHVRTSKTEPLVDEVELIQANPQYAHIRYPDGKEDTVSVRHLAPAGSETCIDPGCESSDVPSQTIESTNVTPQEGSPESTSTPLPQQELAEEAPVPRHYPSRIRRPPTRFESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MUR6</accession>
    <name>A0A3R7MUR6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002449">
        <property type="protein sequence ID" value="ROT70216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MUR6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="42408" checksum="16C6DD8DE2C57E58" modified="2019-04-10" version="1">MPTRWTNTPTPREHNGRRSVKWKGGGEEAHGDDGLRWWIGRRCRASLGSDPQESKAIPAAGQPVTPKESSIPTPTPPTQGRLLRPFHTRRANAVKNSIACSFFRRPRRSPGQRGRHETVRWMPQDPKRNGTPPTRAARAPCASEAYVHRDPGGRGGAPRASRCTLAVDGEGGGRGIRTPRNNTQTLTQFLDEPEHDSADVEVALHPQDPLHLQVGHGDVQLPRPVTDQLTVRHHLEWRFVWTSLARKKISQDFVFLTPFPPFFPSAALARTHTHSNSIFLGVESRVNTTHKPTLAACICKGENHLPSQDAATPRHTRGLDIAWVTHSSFSRARLATRDRTITNKCLSCSPFKPAARPFGGHHPPKPPAARASQSWKTLLSLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MXY5</accession>
    <name>A0A3R7MXY5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cuticle protein AMP3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_009266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MXY5"/>
    <dbReference type="OrthoDB" id="6359117at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF237">
        <property type="entry name" value="CUTICULAR PROTEIN 65AU, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018706296" evidence="4">
        <location>
            <begin position="28"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT72356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="15840" checksum="B278CFC2B9904DBA" modified="2019-04-10" version="1">MGTTAPLKHSSSMHLILLVCLAGLVAASPMPQPQNRHPEYTAETLLDEREDQGDGNFRYRFETSNGIKTEKVGTPGSKGQSNMQGAFSFPFPEGGVAEFTYVADEFGYQPSSDLLPVPPPLPEHVYRLLEIAEQQRAQGITFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MZF5</accession>
    <name>A0A3R7MZF5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasminogen receptor (KT)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002037">
        <property type="protein sequence ID" value="ROT73320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MZF5"/>
    <dbReference type="OrthoDB" id="10256697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019319">
        <property type="entry name" value="Plg-R(KT)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13411">
        <property type="entry name" value="PLASMINOGEN RECEPTOR (KT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13411:SF6">
        <property type="entry name" value="PLASMINOGEN RECEPTOR (KT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10166">
        <property type="entry name" value="DUF2368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17738" checksum="54A6FF0D3C0581E0" modified="2019-04-10" version="1">MGNSADKGLNENLRRNHELMAESQRIGLERQIHMQNEMREKLMSMQIARARELLYWFGAFYAISAIGMIAGFRRTRKPGTLVPLLPLTFIVAYQADLAYGSKLNRIKMEAENILVFERELVSMPMGVPTPASIDEARERQEESKRLNKVHEVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N0C2</accession>
    <name>A0A3R7N0C2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001976">
        <property type="protein sequence ID" value="ROT73877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N0C2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="49440" checksum="9FD487EE1470B086" modified="2019-04-10" version="1">MVPPAGTPPAAAGGLAAPAVPRGRPGVPGLPPAVASPRSTPTPFKLRRFSMGTDRAGSPCASNPGAASVLQMTAAQLEQHMAATQAAKQAAMNLQQQQQQQQQFAAQNYHQQSAQDHAQQNSDGPAEPPLQQQQQTGVFYPMPQHPASPSPAPQQKTVFENPRRALATTNSHAVSRHAPQQDMQRPYRHSPILFRDPATEPRSPPASRPGSVVLRERDPNSPTPGSRPTSALLRDRKGKKKTTQNNLSSPLHPLWFIFLAPPSLSLSRLSPVFFLSLLLAALLFSFSFLFVLDRFSSLFPIFRGSSSLSLTRFSLRLLSSSLVVFPSPISPILPLPSPPLCSPSSFFLIDGFFPSPPLFARAPLFSSFPLSSHSPPPTFPTLIPSLPLHPLSSFFLPPSSFPFTPLSFSSPLHLSLLFPLFSFSPSFSSLPPLLLSPSPASLFPSNTGYFSHQYDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NKJ8</accession>
    <name>A0A3R7NKJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004538">
        <property type="protein sequence ID" value="ROT60812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NKJ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="49014" checksum="E04A3B98B8A99CCB" modified="2019-04-10" version="1">MLDSYPNRQGAHLERLPPMPPRSEHISTPPIAKEHISTPPIAKEHISTDRPSPKEHQSRTSAHSQGATSRTPPDRQGSTISNFTPIGARSTSSTPPASPRSSNSALLRILPRSTCSTPHAIPRSTSDSSPIVQGAHPRLLPIAKEQQHISRTRPPIAKEAGTSRPSGPYRAKGAHNTRTPRISAPRSTSFDSAPYRHSQPHLRPPRSNRPTEHIDLDLPSHHCQGARISLFPSATGAHLDSGSGPPGASRPRPAFALPAASPKEQHLDCRPSQRKQHLDSSRIAKEHISIAPPQSPRSKAHLELRSQSARGHISNFAPIANQEAPSRLRLHRQEHISDSHAPSPKEHILFEHRSTALRQVHTSRPPAASHKEQHLRLAPIAKEPSSSTPPIAKATHHSSTPPPTPAKKSHARLPPSAKLTHMLDSLTILALGSSISTPLLSGQGSTSRLRPCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NS31</accession>
    <name>A0A3R7NS31_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_016751</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003107">
        <property type="protein sequence ID" value="ROT65274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NS31"/>
    <dbReference type="STRING" id="6689.A0A3R7NS31"/>
    <dbReference type="OrthoDB" id="21182at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016324">
        <property type="term" value="C:apical plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042562">
        <property type="term" value="F:hormone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000181">
        <property type="entry name" value="Low-density lipoprotein RecePtor related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000005">
        <property type="entry name" value="low-density lipoprotein receptor-related protein 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000037">
        <property type="entry name" value="Signal peptide, CUB domain and EGF-like domain-containing 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000062">
        <property type="entry name" value="Terribly reduced optic lobes, isoform AI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026823">
        <property type="entry name" value="cEGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF14">
        <property type="entry name" value="MEGALIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12662">
        <property type="entry name" value="cEGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 11" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="363"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="172"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT65274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="47972" checksum="85C3EFFFCCBEA919" modified="2019-04-10" version="1" fragment="single">SLSLPLFIRLPLPSIKISFIGLIFNFGESLGQKNTQVVTWSRWFAGWKNHQGTFTCFLEEQQKCNINLCEINNGGCAQSCHPVPDNKVECKCNSSLKLVNENKMCVPKNYSCDANRFYCANGKCISRLWACDGSDDCGDNSDEDRNYCTYHTCSPSEFRCKNGRCIFSTWKCDHEDDCGDGSDEEGCEYPPCADGEFTCANHRCIPQAQIYICDGDNDCLDGSDEDDRHKCNNRRCDEETEFTCNDNKQWGRAMCIPRKWVCDGDPDCVDGADENTTMLNCPEPEECAENQFQCNNRRCISKTYHCDGEDDCGDNSDEVGCEPEKTCGPAEFQCKNGECIAMKLLCNKVSECSDGSDEPLHCNVDECAKVELHQCGHKCINTIIGFECACNQGYKLMPDGKACEDINECVETPGVCSQKCYNNPGSYNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NSW5</accession>
    <name>A0A3R7NSW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003027">
        <property type="protein sequence ID" value="ROT65853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NSW5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="534" mass="59526" checksum="1581D26043A184C4" modified="2019-04-10" version="1">MTPIKPTRRHHESHSANPTHNSTTQPHTHDTYIHPPARTHTHPHTHIYSSRYTQHTSHSPALNLHTHSTHTLTGTYSPPTHTIRHTARTTWFHVVHTRSHTQSTSPALTHKIGTLTLHTHDTASLSRLTQTHTHTHIIITQTHAKPSASPNTTHTPHNTQHTYSLPTHTQPTSCAHHESHSAALATQHSPTLTTLYSTPTHTHNHTHAHTESHSPALTQHLHPHTSQPYSHHPHPHTYHPPHTHTHTTHTGRKPIASPTQSSPKFSLPLVVPSSHSFISRFPHSLLLPISFSPSFLPRSSSSLHFSLLVVCLPSYRFSFLSDFLLPFFSDTSHLPFLIYPFYYSSCFLSLPSSYSLLQFCLGFLPSSFLSYSSCYSLYLFPSIPLIVINTPFLLSPSRSHSPFPFPFISSSLLLRNYLLFYPSPSSVLALLPSYPPLPSPPVHLLLLALPLPLLPLPSPYSLTPSIPPSNPPSPSLHHYISSPFFRVLSSLCPFSPPPTLFSIPPLAPFPAPLSQTSFLSRTFRLSPLSPFPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NY50</accession>
    <name>A0A3R7NY50_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Palmitoleoyl-protein carboxylesterase NOTUM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011808</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pectinacetylesterase family. Notum subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002493">
        <property type="protein sequence ID" value="ROT69956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NY50"/>
    <dbReference type="STRING" id="6689.A0A3R7NY50"/>
    <dbReference type="OrthoDB" id="2015280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004963">
        <property type="entry name" value="PAE/NOTUM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562">
        <property type="entry name" value="NOTUM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562:SF122">
        <property type="entry name" value="PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03283">
        <property type="entry name" value="PAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="51814" checksum="9FB5CB974D49844B" modified="2019-04-10" version="1">MAASSWRSGGCCSPLNLTHGHKLILEGAGSSAGGVGALVNVDRVAAQLARQGIRAEVRAVADSGWFLDNEPFRAPQAIRRARSCGAAHPDACAEQYPRHPWYCYFGYRLYETMKAPLFIFQWVFDEAQMTADNVGKPISKEQWDYIHSIGERLRKTFENVTALFAPSCISHTVLTKRDWSSVKIGEVSLPQALYCWDITPAAALHAKSSSGRPHSRRKTQEESGQDEDDLPNARAGEDRDGGGSSKKSHRKTGRRQSQGAGRPDVLNREMLADSPRDSPKGPDQHAAPPYLVESNAIDTTQESTKLKQQQEEAEKREDGKKELTRKERRRRRRKKKNRNKGKKKRKRNKKRGKKRRRRQRNKDKSGKKKRKPKAPSRESGEDLHEGVCPADTLHLTDRCAWPQCNYACPILLNPFTGEEMNFIELLKSFGLDMASVANALGIDIHTLNSMANDELLHILTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P2X9</accession>
    <name>A0A3R7P2X9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007538</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001956">
        <property type="protein sequence ID" value="ROT73977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P2X9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="57636" checksum="1DA066EDD13CD9A1" modified="2019-04-10" version="1">MIRVVSVDPDSETVIRGFHERPLKTWGCGLFVSPFLDSRSFFFLYLLSRVSLFVSCSLFRSFSVFFFVSFLRLLLLLFLLSRVFLFPSSSSSSSSFSFLFSFVFLLLSRSSLVRYFFCFCRLFSPLLFFFSFVIFISCLFSCPVLLYFVFLLSSSSSHSPFSLLSLRISRYSLFLFFLPFTSLFLTRYSLLSSLLSCLLPCLLSPFHPIPSLLYLFLSRPFFPFSSLVPFLLLSSPFFRPSPFLSSDPNAYTLKSSITVMCPHYTMPKPLTCPFSPSAHYEQLYHSNTHTHKSNTNPHHTRQNPNHSAHNTNTPHSPFPPFLLPPSPSPLFPSLPTLPLPPPPLPPSPFPPPLPPPHFPPPSIPFPTPSPFPFLPPFPPLPLHPIHLPPPHSPFVGLTPPPPYEKKNPRRDMQMSPDTYIKITEENPIPPPPLPSPSLIPLPPFHSPFPSPLFPPPPMLSTHEANRGQLFVSLTSPLSRWLRSYQEPCRYLLGDWHTRLGVSLRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5E7</accession>
    <name>A0A3R7P5E7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Myosin-XVI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004016">
        <property type="protein sequence ID" value="ROT61706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="642"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="759"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="907"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="776"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="822"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1192"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1247"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1371" mass="153163" checksum="0FE1656C4637210D" modified="2019-04-10" version="1">MLYTKLQEILSLNRSFLHEASKLTSHGACRLGSRGNRFDRTFYEGAKETPNSEKRVPGTRDGRGGREKRQGQGIQNVPRDSCVAIPNYICLSGHANLPPPTSHSLPRVFSPRQLKPTAILLPPPQRLQPPTFNFKQLALSPRPHVSELRLSSPSLQDRALYSPRLSLVPSLPKPSSPNRRESERATSRIRAGHFQNPNGRHFPESTATSRNPKGPLPESETGHFQKSRRGHFQNPKGPLPESEGATSRIRTGHFQSEGATSRIRGEEIRRGHFQNPKLPESRGATSRIRTGHFQESKGPLPESERATSRSERGIQGPLPGERATSRNPGATSKTGHFQNPGPLPESRAGHSRIRTGHFQNPKGPLPRYPKGHFPESEGATSRIRTGHFQNPNGTSESDGPLPESRTDFQNPSGATSRIRTGHFQNPNRGHFQNPNGPLPSERPSERATSRIPNGATSESERATSESERATSRIRTGHFQNRTGHFQKSEGATSRSDGPLPESEGATSRIRRGHFQNPKGGRGPLPESERATSRIRTGQLPESERGHFHGRIRTATSRIPKGHFQNPKGPLPESERATSRIRTGHFQNPNGPLPESEGATSRIRRATSRIRTGTSRIRTGHFPLPESERATSRIRRGHFQKSERGHFQNPTGHIPESESGRHFQNPKTATSRIRRGHFQNPRATSRIRRATSRSGPLPESERATSRIRTGHFQNPKGPLPESEGAHFQNPNGPIQESERATSRIRNFPESERARIRRGHFQNPKGHFQNPGHFQNREGATSESGHFQNPNGHFQNPKGPLPESRRGHFQKKGPLPERGHFQNPRATSRTGHFQKSTNPKGHFQNSDIQNPNGPLPESNGPLPESEGATSRIRRGHFRIRGPLPGGHFQNPRPLPESRIRRGHFQNRAEIRGHFQNPKGPLPKRGTSRSGPLPESERATPSTFQNPKGATSRIRRGHFQNPNGPPNPKESRIHFRIRGHFQNPKGPLPESEGATSRIRTRIRGPLPEFRRGHFHPIPKGPLPESNGHFQIQTSRIRRATSRIRRGHFQNPGPLPIRRATFRKKEGPPWATSSKSEKGPLPESERGHFQNPKGESERATSRIRTGHFPEIRRGHFQNPKGPLPESEATSESEGATSRIETGHFQNPKATPESEAERATSRIRRGHFQNPKGPLPESERATSRIRRGHFQNPKGPLPESEGPLPESEGHFQNPKGHFQNPNGPLPESRATSRIERATSRIRTGHQNGPLPESERATFRTGHFPESEGPLPESEGATSRIRTDHFQNPKGATSRIRTGHFQNEGPLPESERATSRIRTGHFQNPNGPLPESERATSRIRTGHFSERESERPLPESERATSAPRRWGWPVLCYRMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD05</accession>
    <name>A0A3R7PD05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002860">
        <property type="protein sequence ID" value="ROT67056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD05"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="433" mass="47011" checksum="D566FB1BC38C044D" modified="2019-04-10" version="1">MNTKVPSRMPCPGLRLCHPTHSSLKVTPLPFLFPPSPFTFLLSFSFHFPFPSSPSPLTFLHSSPFPPPLAPSSSLPPSLLPFHLSLLFPLLSLPIISPPPFSPSSFPSLLPSFPPPFLFSSSPSLFPPPFHLPLLLTLSRPFPFHLPYSPSPSSFPSLSLLTPSVFLLPPSPPRPFSPLLNRPPFLTPFLLLPLPRPPPLFSPAHPHLLRTSLSPPPPPPSLSTLSHAHPSILHPLPPLPPPQPHHYPSDIPPTRPSAPPPTGPSAPRPPPITRMNHTRGNTFWASLIALTSLPYLPPPLQVTFLLPSLSLLPLSLSLFPRSCILRTLSPVLSVCFVLSFIFSLFLGLSPPIDILSSLPHPLLSFSFPASPPFPPHPPTPLLLSPPSHPYSPISPHPLFLSHPSPFSSPTPFSPLLPTPYSPSPYHPSLPIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE61</accession>
    <name>A0A3R7PE61_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002732">
        <property type="protein sequence ID" value="ROT67993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE61"/>
    <dbReference type="OrthoDB" id="6374606at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="257" mass="28933" checksum="B1BBCCFBF0541C3C" modified="2019-04-10" version="1">MDLRGSATGFRYVLSIVDHHTRFIQLVPLRDKSANRELRAFVDHYVTLFGPPDHLHIDNGLEFSSDEWRSLLEALQVEHSFSVAYHPQSNGVVERTNRTVKDALAVLARQAPLQWPTHLFAVRIALNSAIHRAVGDQPLYLLLGRMALFGKGLTNRQTVDPDLSLARLADARRLAVEVSRKMRETNKAHYDQAARTSGPYEEGALVLGKIQGNRGPLGDHWLGPCSVQKRLGPVSYNVLDLRPPYRTVRVHANQMRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEM4</accession>
    <name>A0A3R7PEM4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000625">
        <property type="protein sequence ID" value="ROT83910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEM4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018590307" evidence="2">
        <location>
            <begin position="50"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="43153" checksum="97DC7EF4F67890EC" modified="2019-04-10" version="1">MTPRTSDAVENWAAPRVASSTSPPWPSPPPPLLLLLFLLLFSSIPPLSLLPLPPSPDSPPPCFSILGPLLCLSSSSTNLSPSLVFPHPFSLPCFSLSPSPIPPLLLSHLTLFPLLLPFLSPSLSSLFLHLPLLPFSFTLPLALSLPPLPFTFLSLSLPLTLFSSFFPFFPPYPSLLSSPPLRSRLPSSPPSNHSPTLTQPPTPVPSPSLHLLLSPPLFSPHLFLLLPSHSLPLSSLTHPLSPNFPPTPLSSFFPPLLYPPPPPTPLSLHPPLSPHSPFHHPPLLPHPSPPPLFPAPFPLFFPSLPPPPCLSHPSSLTSILLHLLLLSNPPRPPILLHLLPSSTPTPLYLLPLLSHLCLSTPPHHSPLPPLSTSSLFHPIIPHSYPLPSHPHPSPARTTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHJ2</accession>
    <name>A0A3R7PHJ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002902">
        <property type="protein sequence ID" value="ROT66697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHJ2"/>
    <dbReference type="OrthoDB" id="6352826at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="155"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="284" mass="30112" checksum="D7E756AE61CB54F7" modified="2019-04-10" version="1">MGLRRRGILAIVGGLGQARADDRLPAALGELTAVLRDLGGEVTAGINKLLSELQQERLRRGEEVQALREQAADNRRALDVLRAELVAVASGRCPAAGHGPLGEGGGADVRAMGAGMGGDERARSASPPGGRGVEGDASADETPPDGDCPRPYKRFGRYCLTLLQERNKWEFARSRCHLHARSMGGGRATVKGDLVVPHDMEAFKAFIASTDFGGAPTGRAWVGGSAEGWGGVWAWVDGSLMNELPWVYSQASGDGSRIAVDHESVFHTVGDDEILWSVCQYLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJV7</accession>
    <name>A0A3R7PJV7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002621">
        <property type="protein sequence ID" value="ROT68931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJV7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="468" mass="50878" checksum="4A3E56EB5D4FC042" modified="2019-04-10" version="1">MSSFLFFFLFFCPHIHVFSFPSLNACFFLFLFFLFSFITIPALFCFYFSCFTSRNFFFSILFSASLFFFSLSPFGLLYFLLHSHHLLPVLSHSLSYTVLPSSPFLCHLFPPLALFLFSLPSCLIIFSLSFLCTYTPSSLVPSPLSFYFLLLSLPLLLSLPLPSSRSFVFSYPSLPFPLVPPLIHLSSVAPLLAPQPSSLILFLLSLFSPLASLLSFIFSLSTHLPLVSSLASLFLSHSLSLSLSHSLTLFLSLSLSLSLSLSLSLFSLSLSLSLSLLLPIPPFPLSFLPIAPYCLTPLLLFLSASLPFACSLTSFFFTSLPDLPSPPPSPPPLPSSLTLSSSPSLLSFLPLLPFLSSFPLLFFCSILLFPCLLPPLLLLPSSPLPLLFSLSPPSPPSRLPFSSPPPPPSPLPPPFLLSPSSSPLPSPLLPSLPPLSPLSLPPPPLAPPSLCATRPFDSSLSSTVSTMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PM60</accession>
    <name>A0A3R7PM60_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001660">
        <property type="protein sequence ID" value="ROT76454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PM60"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="459" mass="51492" checksum="009CA3F8A317EB4C" modified="2019-04-10" version="1">MLLSFLLVHSPPPNPSNHQLPHDQHRTLFRSSSLSYDENNNGLSSSQPSPIPLSRPLPPFLFLRSPSQSLFLPYHHSFILSLSLFLFLFLFFSPSPLPSFLRSPSQSLFLSHHHSFTLSLSLFFSLFFFLFISPSPLSSFLRSPSQSLFLSHHHSFILSLSLFLSFQLSLLSSLTLSIPLSLPPSFLHPLSFSLFLFIFLFLLFSPSPLPSFLRSPSQSLFLSHHHSFILSLSLPTLPPFFAHSLNPCFSPTIIPAPSLSLFLFIFHFLFFFLSFSFSLLPTLPPSFLRPPSEALFLSTPSFLHPLSFSFLFSLSLSLYLFLFPFLHLFLAPSPSFPSPFPSSLPQPSPFPYFPQSFSTPTLPPFSAPFLPPSVHSQQLPLPELPLHFTPLPPLYFPSLLFPSPPSLPHPPPHPPSFPNYIPHTLTHSLLSSLPPSIPHTLPPPSSPPFPHPPSFLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZF1</accession>
    <name>A0A3R7PZF1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">E3 ubiquitin-protein ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024841</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000898">
        <property type="protein sequence ID" value="ROT81987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZF1"/>
    <dbReference type="STRING" id="6689.A0A3R7PZF1"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="127" mass="15282" checksum="4465D75210371A9F" modified="2019-04-10" version="1">MKDLPYHLKKDVDNELRKHNYHYLPTLRALQNNKKLNRRKTKRTSPLKQRDLDDIFIKELCYVGMEVQIKEHLVKKEENKRRAFLWAKKNGQLKECPCCYDDEVLEEDMDTCSADDTHKVCNTCIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q647</accession>
    <name>A0A3R7Q647_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCN TSP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012221</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002551">
        <property type="protein sequence ID" value="ROT69570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q647"/>
    <dbReference type="OrthoDB" id="6367582at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008201">
        <property type="term" value="F:heparin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045597">
        <property type="term" value="P:positive regulation of cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050941">
        <property type="entry name" value="CCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043973">
        <property type="entry name" value="TSP1_CCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11348:SF17">
        <property type="entry name" value="CCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11348">
        <property type="entry name" value="CONNECTIVE TISSUE GROWTH FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19035">
        <property type="entry name" value="TSP1_CCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="CCN TSP1" evidence="2">
        <location>
            <begin position="64"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="11473" checksum="2D97B3D84E8F6ED0" modified="2019-04-10" version="1" fragment="single">MTIGSQIAAVSSNATYACVSLCPGESLPPSAQCHHPHLVAVPGQCCREWMCDTVPGKSVGPPSCRRVSGRWSPCSHTCGAGVSVRWTTDNASCQTINETRLCQLRPCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QB03</accession>
    <name>A0A3R7QB03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003776">
        <property type="protein sequence ID" value="ROT62191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QB03"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="570"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="611"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="685" mass="72326" checksum="6B1D675897B99AFA" modified="2019-04-10" version="1">MLQSSLSPPSHPLLTHSAPPLSPPTHQSHSLPSLLTPQISLPPLNPTRNLTLPPSQSTPQSHSPPSHPLPNLHSRPPLSPHSPISTLPSLSHPLTNLTLPPPSHPAPQSHSPLPLTPLPTHPSPLPNLTPKSQSPESSLSHTPLGPLPICLFPSPLTHSESHSPLPAHPTPNSLSAYPSHPASPNLSLPRRSQPTPHLTLPPSHPNLPAIHSLLPPHATPQSPPSQLLTHPNLTPRPLTPSQSHSPLPIPSAQSHLTLPLTRTPQSHSPRSLTPLPNLTLTPLSRRPQFSLLALPSHRRSPNLISSSHLPNLSSPLHSISLAPSLSPSLRPIPLSLPSLILHSQSPRLSPISPLSPHSPISLSPPSHPHPTALTSPSHSLSSLSTHSPISLSPPLSPHSHSPLPSHPTPQSHSPLPSHPTSPISSLPLTSPSLSPHSPISLSPPLSPLPNLTLSPLSPHSPISVSLPSHPSPSHSSHPHSQSHSPLPLTPLPNPTLSSLSSHSPNIPPSHPLPNLTLPSPLTLPNLSPFPLTPPQSTLNLTLPLSLSPTPLPHFPSPSLSPHSQSHSPLPLTPLPKPPSPLTPLPNLTLPSPLPSHSPSLSPHSIPPPSHPSHSPLPNLSLPLTPISTPPPHSFPLLQLLPPKDMQYPLCKSVHPEPQSLKGKGTERCRVPSFPRHLVMTASRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QG81</accession>
    <name>A0A3R7QG81_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Class 4 HDAC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002936">
        <property type="protein sequence ID" value="ROT66422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QG81"/>
    <dbReference type="STRING" id="6689.A0A3R7QG81"/>
    <dbReference type="OrthoDB" id="437693at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF19">
        <property type="entry name" value="HISTONE DEACETYLASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="3">
        <location>
            <begin position="63"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="348" mass="39280" checksum="75531F7E23CE4EF7" modified="2019-04-10" version="1">MFACRGLRARKCFSKRLLTTLHGNPYHSVRDHLSEEELGQLQRVTRLPVIHHEGYVCPLPPNHRFQMMKFHHLYNILIRDGVIDQQKQVIEPQQVSREVAGTVHSRTYVDKFFDGCTSEQEQRVTGFKWTPGLASRVRYETGGTLLAGKVCLDRGLACSTGGGTHHAFPEYGSGYCLINDLAVTAYRLIESGLVTKVMIVDLDVHQGDGTAFIFQNRPDIFTLSLHCQNNFPLRKQESDLDVGLDVGLNDNGYMSILSEYLPFTIDEFHPDVILYDAGVDPHEKDQLGKLKLTDQGLYNRDMFVLKTAICRGIPVMTVIGGGYDEILALSARHSIIHRVATEVWNNYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QK71</accession>
    <name>A0A3R7QK71_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2'-phosphotransferase</fullName>
            <ecNumber evidence="3">2.7.1.160</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_011656</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:23324"/>
            <dbReference type="Rhea" id="RHEA-COMP:11106"/>
            <dbReference type="Rhea" id="RHEA-COMP:11107"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:76596"/>
            <dbReference type="ChEBI" id="CHEBI:82883"/>
            <dbReference type="ChEBI" id="CHEBI:85027"/>
            <dbReference type="EC" id="2.7.1.160"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KptA/TPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.160" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002470">
        <property type="protein sequence ID" value="ROT70086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QK71"/>
    <dbReference type="STRING" id="6689.A0A3R7QK71"/>
    <dbReference type="OrthoDB" id="419694at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000215">
        <property type="term" value="F:tRNA 2'-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.170.30:FF:000002">
        <property type="entry name" value="Phosphotransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.970">
        <property type="entry name" value="RNA 2'-phosphotransferase, Tpt1/KptA family, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002745">
        <property type="entry name" value="Ptrans_KptA/Tpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042081">
        <property type="entry name" value="RNA_2'-PTrans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042080">
        <property type="entry name" value="RNA_2'-PTrans_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684">
        <property type="entry name" value="PUTATIVE PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12684:SF2">
        <property type="entry name" value="TRNA 2'-PHOSPHOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01885">
        <property type="entry name" value="PTS_2-RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT70086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="207" mass="23443" checksum="C961D128B31FED75" modified="2019-04-10" version="1">MADFPLQGDSKVKTSKALSWLLRHGAAKEGLELLPGGWAKLDDVLKKPKFKRVTVQDIEEVVISCPKQRFGLKEEDGVYYIKANQGHSIQVEDPELTEITLEDRVLEVVHGTYYRHWPSIKEQGLSRMNRTHIHFAPGLPGDSAVISGMRTSCQLYIWINLPKALEDGYKFYKSANNVILCPGNEEGFLPPKYFAKVTDKRTGENRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMN6</accession>
    <name>A0A3R7QMN6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine sulfinic acid decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009231</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002165">
        <property type="protein sequence ID" value="ROT72379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMN6"/>
    <dbReference type="STRING" id="6689.A0A3R7QMN6"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06450">
        <property type="entry name" value="DOPA_deC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000016">
        <property type="entry name" value="Glutamate decarboxylase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677:SF8">
        <property type="entry name" value="CYSTEINE SULFINIC ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="50396" checksum="DDCFF739BD633298" modified="2019-04-10" version="1">MENSPKILQLGLTREGLSFAQVEELLEKVVKYSVKTQHPHFYNQQYGGIDEVALTGAWLTDALNTNQHTYEVAPVFILMERFIIQHMISLFGWPEGDGIFSGGGSMSNMYGMLLARYRLYPDVKRTGIFGRKPLVIFTSDQSHYSFAKGASVMGIGMDNVISVATDSCGRMLPQALREEVAKARARGGEPFFVNASAGTTVLGSFDPFEDIADVCQEEGLWMHIDACWGGSVILSKTHRHNLNGIQRADSVSWNPHKMIGTTLQCSPFFVRHKGLLHECNSASATYLFQQDKFYDVSYDTGDKSIQCGRKVDAFKLYFLLSTKGMDLVEKKIDAAFSASDYLNEQLGVRPGFRRVIEKPQCTNTCFWYIPPSLRDQPETPEWWEKLSKVPSIIKARMVQEGTMMIGYQPLASKNLVNFFRLVNTSTPMTTNADMDFVLDEIERLGKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QN30</accession>
    <name>A0A3R7QN30_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QN30"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="49929" checksum="DF2189DCAFAE74C0" modified="2019-04-10" version="1">MVSLVFPSLAFPSPLPRPLTPPPHPSTPSLVRKSSITPVCCFPSFCHPLPLPLPPLICLKPSCPSPLPCPNLPLPFSLFRTVFAFCPTVALLPYPHPPARALPPTPPHLLRACHPTTPPCYPTTPTHSHLLSALLPCYPTTLKPLLTSPRRRPSPLLSSSPLVPSLNHDRARQRRSFVQHHDRGHLRHRSREDIEGERHRGRGHRGRGHRGRETSRERDIEGEDIEGEDIEGEITSIRDTNPQRAIQSPPSITLNHPAINPPTDREPHSPPPLRTHSVSQDEALLKAPAEGTPSAHRRRVTLLSRRPSADSEAPAEESDHPPPTRQRNRPFLPHTKERPLSPSHKGTAPFSLTQRNQPFLPHTKEPPLSPSHKGTAPFSLTRILRQTISETLVLHLHFPFLPMILPITDTSEAWDVFTLHLASIKGTAVTSAVISSCCLSLSLLAYDEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QSV0</accession>
    <name>A0A3R7QSV0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal Pro-X carboxypeptidase</fullName>
            <ecNumber evidence="14">3.4.16.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Proline carboxypeptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Prolylcarboxypeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_004489</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Cleavage of a -Pro-|-Xaa bond to release a C-terminal amino acid.</text>
            <dbReference type="EC" id="3.4.16.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.2" evidence="14"/>
    <dbReference type="EMBL" id="QCYY01001595">
        <property type="protein sequence ID" value="ROT76904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QSV0"/>
    <dbReference type="STRING" id="6689.A0A3R7QSV0"/>
    <dbReference type="OrthoDB" id="2130629at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.980:FF:000002">
        <property type="entry name" value="lysosomal Pro-X carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF38">
        <property type="entry name" value="LYSOSOMAL PRO-X CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0458">Lysosome</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 18" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018634944" description="Lysosomal Pro-X carboxypeptidase" evidence="18">
        <location>
            <begin position="20"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00066456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00073691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00076475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00076608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT76904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="487" mass="55055" checksum="01C388C7C6175419" modified="2019-04-10" version="1">MARHLLLLTLSLWLSCCSSYKYETYFFKQKVDHFSFADQDSFIQRYLISDRHWDHRGGPIFFYAGNEGDITLFAENTGFMWDIAPEFNALVIFAEHRYYGISLPYGNKSFTEPKYSGYLTSEQALADYVELLAYLKTVIRGAKNSPVIVFGGSYGGMLAAWFRIKYPHIVQGAIAASAPILQFTGLTPCEKFGQLVTADFAKESKECAEVIRKSWAAIDAVTADDSGLAWLTKEWKLCKPLKGKDDVKTLKAYLMDVWTNLAMVDYPYPSDFLAPLPAYPIKEVCSQLTNPGHGPKLLLEELFSGLTVYVNFTGETKCVNIDQQADVRLDDQGWDFQACTEMVMPFCYDGVNDFFEPADWNFEEYAENCHQKWGVYPRPMMAPKIYGGKELSAASNIVFSNGNLDPWSTGGVLWNVSDSVVSVIIPEGAHHLDLRGSNPNDPESVIDARRVEKEFIKTWINEYRSAHNLIGNDIKNTNTFEVEEPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QW14</accession>
    <name>A0A3R7QW14_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">C-type lectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001126">
        <property type="protein sequence ID" value="ROT80360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QW14"/>
    <dbReference type="OrthoDB" id="6353463at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018547148" evidence="1">
        <location>
            <begin position="20"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="18641" checksum="8F077AB60F5C7FBF" modified="2019-04-10" version="1">MFRLKTLLLVAAAAVTVGAQCPDTFFEAGGGCFHVVDTGDTDITWEDARETCIGLSDSSWTVDLASLDSTAQLEAFAEAWDTVGADYRPYGYMWVGFTRETGQWANLDGVPISLYSNMWRESHPHDMNMYVFIEDVTMTSGIESRGRFYASCTMKDALQRALCRAFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWD1</accession>
    <name>A0A3R7QWD1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001094">
        <property type="protein sequence ID" value="ROT80664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWD1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030414">
        <property type="term" value="F:peptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008197">
        <property type="entry name" value="WAP_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51390">
        <property type="entry name" value="WAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018792979" description="WAP domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="WAP" evidence="2">
        <location>
            <begin position="185"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="236" mass="23563" checksum="1BA2588ED75EBC42" modified="2019-04-10" version="1">MNPTRCLGLSICVLLLANGALSQQGSTGGGRGGRQNRFFGGLGSSTGALVSGLASTGANLLNQLAFQGSGGRPGFGGSNFINRPGGFGTNFGGNSFGNRPFGGNSFGTGFGGNNFGNRPGFGGNNFGSGFGNNFGNRPGGFGGNNFGNRPGFGGNNFGSGFGGNNFGSGFGGNRPGGFGGNQFFTVNRSGQCPAADPTCPIRTGPSVCNSDIICGPGEKCCFDSCLEYSTCKRILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWM2</accession>
    <name>A0A3R7QWM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Double-stranded RNA-binding protein Staufen-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_000388</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001055">
        <property type="protein sequence ID" value="ROT80874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWM2"/>
    <dbReference type="STRING" id="6689.A0A3R7QWM2"/>
    <dbReference type="OrthoDB" id="10037267at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032839">
        <property type="term" value="C:dendrite cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043025">
        <property type="term" value="C:neuronal cell body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098964">
        <property type="term" value="P:anterograde dendritic transport of messenger ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007281">
        <property type="term" value="P:germ cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035418">
        <property type="term" value="P:protein localization to synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19857">
        <property type="entry name" value="DSRM_STAU_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19859">
        <property type="entry name" value="DSRM_STAU_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19861">
        <property type="entry name" value="DSRM_STAU_rpt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000007">
        <property type="entry name" value="Double-stranded RNA-binding protein Staufen homolog 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000024">
        <property type="entry name" value="double-stranded RNA-binding protein Staufen homolog 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000013">
        <property type="entry name" value="double-stranded RNA-binding protein Staufen homolog 2 isoform X3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051740">
        <property type="entry name" value="DRBM-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032478">
        <property type="entry name" value="Staufen_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46054">
        <property type="entry name" value="MATERNAL EFFECT PROTEIN STAUFEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46054:SF3">
        <property type="entry name" value="MATERNAL EFFECT PROTEIN STAUFEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16482">
        <property type="entry name" value="Staufen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DRBM" evidence="5">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="5">
        <location>
            <begin position="127"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="5">
        <location>
            <begin position="234"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="5">
        <location>
            <begin position="345"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="529"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT80874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="69158" checksum="1E09EAD7872E09B2" modified="2019-04-10" version="1">MTPTSSGVGVSVGGSSPTNSSSMSNSMCLSNTDPSTSSKEKTPMCLINELARYNKIQHQYCLTDEKGPAHKKTFTVTLRLGESEEYTASGPSIKKAQHSAAAIALEKTQFKHPPPKTQRQNKQTKLTPTVELNALAMKRGEAAVYTFMETPRPPNPYFNMPPNIRAMYNQKYYGRPPLYPIFFVTLRVGTREFIGEGTTAQQAKHNAASKALKLMKQLPMPENATTCTQGDLKSPISLVHEIALKRNLTVAFEVIRESGPPHMRTFVTVCIVGEYRTEGEGTGKKVSKKRAAELMLEELRKLPALPPTSLIRVKRKPTTKKKSRNLIKVGQEEQKAAPEYGQGINPISRLIQIQQAKKEKEPVYTMLAERGVPRRREFIMQVTVGNQSAQGSGPNKKLAKRAAAENMLQLLGYSRPQPQPGKPAIKTDGAHSDPDKTRKVTFLEDGGETRGSDSAVVGGVNNVNHMGGPAVGGGRQLVPGLIMMPDGSALHGFQQVQPQGMGMVSVGPMVNMQATATIAKELLKSGNSPTAEAMVKQNPPTGPQGPPQNQTVPSTQAVRPKDQLMYLAQILGLQVQFTDFPKGNKSEYLSLVSLTTSPPHVSHGAGPTIDDSHDQACLTALRALAKMGLDTVTAAKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SHA0</accession>
    <name>A0A3R7SHA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein melted</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_021018</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004278">
        <property type="protein sequence ID" value="ROT61233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SHA0"/>
    <dbReference type="OrthoDB" id="5869902at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010314">
        <property type="term" value="F:phosphatidylinositol-5-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039888">
        <property type="entry name" value="Melted-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21630:SF10">
        <property type="entry name" value="VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21630">
        <property type="entry name" value="VEPH-A/MELTED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="287" mass="32023" checksum="06CD3F40AA5D3A5A" modified="2019-04-10" version="1">MHELFTQVLSHKDLSKAGDLFNVSDHVIVNDLTDVINKIREIASLPEYTRNDNDQSVVEICITRVTSAIRETGSIEQHAEALVALLQTCLNHNLRPSSRDSDPPHAKIASDVVSCIFLNYHKREVMALALPVAVKFLHKGNKELSRNMSSYLSLAAIEAADLLAMHIQPIIDSVISGNYSLSRVLPQIYAVKKEPIHDHVMTLVSLLPQCDTNEKLGLLMLFSLVAKNRPALLEPSLPQLVECLSISGTSMATLQIFVELCSWRPGPFTEHVTRLKSIIEQQPHCWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-05-03" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLU9</accession>
    <name>A0A3R7SLU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_015726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002965">
        <property type="protein sequence ID" value="ROT66264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLU9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT66264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="422" mass="46412" checksum="9FE18C54F5697DEF" modified="2019-04-10" version="1">MGAEADFMWYGQRRDFMGMGAEAGISWMGQRRISWVWRKRRDFMGYGGRGGISWGMGAEAGFSWVFHGGRGGISWGMGAEAGFHGVWGQRRDFMGMGAEAGFHGYGAEAGFHGVWRQRRFHGYGGRGGISWGMGAEAGFHGYGCRGGISWVWGRGVSWGMAAEAGFHGYGGRGRDFMGYGGRGGISWGMGQRRAWVWRQGGVWGQRRDFMGMAAEAGFYGMGQRQDFMGLAAEAGFHGYGGRAGFHGGMGQRISWVCGGMRQRRDIMGYGRGGISWVWAEAGVWGRGGIHGYGAEVEFHGYGGRGGISWVWAEAGISWVWRQRRDIMGYGGRGGISWGMAAKAGISWGMAAEAGMVWGQRRDFMGYGARRDFMGMGAEADFHGYGGRGGISWVWRRGGISWVWRQRRDFMGMGAEAWLWMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SM44</accession>
    <name>A0A3R7SM44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002911">
        <property type="protein sequence ID" value="ROT66657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SM44"/>
    <dbReference type="OrthoDB" id="6376637at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="229" mass="24518" checksum="21DC2BF69C3590A3" modified="2019-04-10" version="1">MGNGTPHLTLLGKFNSPLSCPNCPSCYRCPNCPSCYRCPNCPSCYRCPPTTVPPPPRTIASLPAITSEPPYQPPTSKDKVTTAGVGGGIAEQPVHQPPTSTPDLALPPAPSKEEESWVWSLGGVGGVPVVPLTIVAVVVLAVLITLGVVWWRRRRSQSKNVTSKAVQLDSIRHTGYEPIDTREEKEGGAEGPRENEGVVRDPQLDQMDDSYGPQVNHGRPLTSFSNSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQ34</accession>
    <name>A0A3R7SQ34_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Zinc finger protein 593 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011314</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Associates with pre-60S ribosomal particles; released from the pre-60S particle very early in the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002431">
        <property type="protein sequence ID" value="ROT70409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQ34"/>
    <dbReference type="STRING" id="6689.A0A3R7SQ34"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="98"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00057732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00065398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00068297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="15808" checksum="2C8036CF4E2122CA" modified="2019-04-10" version="1">MGGGPKRRKKSSPGLKRLLKTKRKTKDLDQIDDDLKEENIHKLLHQEVDPDLPGDAQHYCVHCARYFINREALKTHFKSKPHKKRLKSLELEPYTIEESERAGGLGSYIPPKKRKIETQPMDDETFDPTKEDVDMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVQ7</accession>
    <name>A0A3R7SVQ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative deoxyribonuclease TATDN2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001511">
        <property type="protein sequence ID" value="ROT77559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVQ7"/>
    <dbReference type="STRING" id="6689.A0A3R7SVQ7"/>
    <dbReference type="OrthoDB" id="6340875at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46363">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46363:SF1">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="179" mass="21064" checksum="47054FA03ABA9676" modified="2019-04-10" version="1">MQRYLKLSYDQQRLLTEKYSPGFIDTHCHLDFLFSKCNHIGTYAKYQSTREGQDVFPVSYEGCIANFCQPWTFKRISWWENFLAESNVWAAFGCHPHYSSSFGVEEEGYLRHALQHKKTVALGEIGLDYSCKNNHSRELQQIVFRRQLKIALEFNKPLVIHCRDADEDCINILKEARFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SX77</accession>
    <name>A0A3R7SX77_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001222">
        <property type="protein sequence ID" value="ROT79593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SX77"/>
    <dbReference type="OrthoDB" id="10047268at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="631" mass="69604" checksum="20CAFD7C839D9D94" modified="2019-04-10" version="1">MLSILFVYHSLVSSARGPSPLLHEHSQQVLLPENMRPVDREDTAPPETQDDVTRASVKEEMPCEAEARPQTPPTPVEQSPEAEVGEASETEEDLNDEAEGDVPRAEETEEGGAPRGSAGECRLESARERVESDTPDGMYDKLTICDACETRHHPSRECTSAADCVRASRSHVDSGTRETPLEPPEEPEISSRLPAPRGRLMRQGQGPTPGQQWSATLNRPSRRGRCVPTPVDPRGVRSQTEPPANKPPPDLLQVSWVWETRQPPRVASVRRRPTRKISCRRKIRPRLTIRKATSRRSSISPQHRASPAKDEDETWAECEEEEGGEAPAEVAERRSPIAPDVLLTGTHAAPGLILASTPQPNRDGIAEEAGPPPGPPPEVALRNTRNLNYFQTASRAVKQRWRNSDIVLPKLLRESDLYGSEKENDIIYLDLRRQLRDSLQRQRSVRRRSVPAVVGVKRQGSFSPRNSLGRNKAVTWNQKYQAVMGLKRAGGGPGRGGADCPVIQVTKAAEGAATPASEGEGEGDWRSLCSTPTSSPHHALLGLDLPQKKPNVLKKLWGRLRHSVPRSLSPSRNQSRDQPASDRHPNGLWLLSLNADINDGCLPVCHNFPFENLTALTALTPSLHSIWFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-09-13" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SY82</accession>
    <name>A0A3R7SY82_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001055">
        <property type="protein sequence ID" value="ROT80868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SY82"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28259" checksum="95708245F6897C26" modified="2019-04-10" version="1">MAEQQEITRRQWCREKVDIICSALQWLNRKDVEEYVKDCKDENEVETLFSMLSEGLSNIEKQPNQAPNDDCDVSSPQPEGATAMTTEYVEEFVNEITGEDTGVAELKLIDMFPDVDPEYIKKRCKRTQGDSDLISALTSELLDQQDGGGLDALHQLLRGMSLDEYQANFADFELLLCTNFLISVKLGFRQCAICCSDNLSRDRMLRVSARSITYSAICCSDNLSRDTEWATFSQLAASRQLILLILPINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9B6</accession>
    <name>A0A423S9B6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VmcE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004597">
        <property type="protein sequence ID" value="ROT60728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9B6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="45182" checksum="4A727CE77490E07F" modified="2019-05-08" version="1">MEMEQGGSGWNRRLRMEQGGSGMEQGGSEMEQGRMEQGGFEWNREGCREWIRMEQGGSEWNREGSEWREAQNGKGEAQDGTGRLSTQNETGRLRMEQGGSEWNREAQNGTGAQNGTGRLREQGRLRMEQGGSERNREAQNREGSEWNREAQNGTGRLRWNSGWTGRLRMEQGGSGWNREAQDGTGRLRMEQGGSEWNREAQNGTGRLRMEQGGSEWNREAQNGTGRLRMEQGLRWNREGSEWNREAQNGTGRLRMEQGGSEWNREAQNGTGRLRMEQGGSDGTGRLNGTGRLRMEQGGRMEQGRLRMEQGGSEWNREAQDGTGRLRMEQGGSEWNREAEWKQGGSEWNREAQGSEWNREAQWNRDGSGQGGGFQGGSDREALRLRLEQGGSVTSDRRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SC03</accession>
    <name>A0A423SC03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dnaJ-like subfamily B member 6 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004034">
        <property type="protein sequence ID" value="ROT61693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SC03"/>
    <dbReference type="STRING" id="6689.A0A423SC03"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="3"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="212" mass="23345" checksum="153685FB043102D0" modified="2019-05-08" version="1">MVDYYKVLELNRSASQADIKKAYRRLALKWHPDKNPDNQDEATKKFKEISEAYEVLSDEKKRRFMTNLAKKDFKQEVDLDLQGLAHPAQRVIMGTIVMMTISTTPSQRSLSETLKKCSENSLAAIPLQNCSALTPSITTVGAVDKADTEEVQILLSHIISAIQIPSAAISSILSALFLAQGCSRLSQILTLLVVAALPHFPRSPLPQLGALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFZ8</accession>
    <name>A0A423SFZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018966</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003479">
        <property type="protein sequence ID" value="ROT63156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFZ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="502" mass="53856" checksum="88C2F94C8462190C" modified="2019-05-08" version="1">MGIRNPFWHSPLSLLSPFPSSSLSSLLLLFSLLSPFSSSLSLSSLLSSSLSSLFPSFLSSLPTLLFSLLSPFPSSSFSLLSLLSPFPSSPLLLPSSSLSFLPSPPLLSPLSLPLLFFLLSPFSSSSLSSLPSPPLLSPFSLPLLFSLLSPFPSSLSSLLFPSLFSLLSLPLSLSSSLSLSSSSLFSSCTIISSFLLPFFFFFPLPFSLLFLFLLFLILFLLLLPLLFLLLPLLFIFLLLLLLPLLFLFFFLPLLFLLFLLPLLFFILLLYLIPHLPLFLPAPHFLQLIFISSSSSSLSSSPFSTSSSSSLSSISSTTFSSSSLLFSLLLRLLLLLLFSLLHLLHHILLFPFLFSLLFFLLLPLLFSLLLPPPSSPFSLSSSFSFSSTSSSPLSPLPPSPLLSAPPPPLPLPSSLHLSPPLPLPPPPPFSPPPSSPLLPAPPPPPPSPPPPPPSPLPPSLPPPPSPPPSPLLPAPPPPPPLLLLLPFSSSSSIPSNIPRPCEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI18</accession>
    <name>A0A423SI18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003362">
        <property type="protein sequence ID" value="ROT63877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI18"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="449" mass="47822" checksum="7B86B78CEC167893" modified="2019-05-08" version="1">MTFLLRLPPPPFSLLRLSSFASLPPPHSLSSFSSLPPILFLLLLPSSIPSPPPPPPPFSLSFASLPILSLSSPPFLTFSLSSASLPHSLLLRLPPPHSLSPSSPFPHDLSPSASLPSILSPPSPPSPPPILSLLRVPPPPSLSSFASPPPHSLSPSPPFLHSLSSFSSLPPFSLLLRLPPSFSLSPPSPPPPHSLSPSPPFLHSLSSSAPFLHLSPPSPPPPFSLSFALPPPPPILSLLRLPPPFSSSFASLLPFFSSFAPFPPFPLLLRLPPPPFSLSFASLPRHSLSSFASSPLPPFSLSFASLPPSLSSFSSLLHSLSSFPPFLHSLSSFSSLPPFSLSSASLPPILSPPRLLSSHFLSSFASFPPPSLSSSLPFLPSLSSFASLPPFSLSSFASPPPWRSWRHEPISEKGQVNTGCLCGLRHCRDEALALKSRERESRQEILSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKM2</accession>
    <name>A0A423SKM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003199">
        <property type="protein sequence ID" value="ROT64742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKM2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="620"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="814"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="844" mass="95577" checksum="38F60036B7CE95E9" modified="2019-05-08" version="1">MASVASGSGSHKRLETDTSKPQLENGYKQTTARKRIQANHSSKTDSSQTKTRKRNTSKPQLANDTSKPQLEKRIQANHSSKNEQATTASKRIQATTARKRIQATPQLETIQATTARTPISKPQLENGFKQPRSKRTKQTLARKRTQKTTARNGTQTNHSSKTDTNKPQLEKRITSNDSRKRTQKTNSSKTDTNNHSSKRNKQPRSKRIQVNHSSKRTQTNHSSKTDQTTTARKWISKPTARNGSSATTARKRNTSKPQLENGYKQTTARKRIQANHSSKNDNPSKPQARKRIQGNHISLENTSKPQPKRISKPQSRKRKQQLENGYKQTARKAQQTTARKRSKRNKQTKLRKTDTSNHSSKRYKETKARNDFTESKPQLENDTSKTTARTQIKQNQVSKTDTSQTQLRKRIQATTARKRTQTNYSSETDTRNPQLGNDTSKTTARNDTSKPGNGYTSKPSWKRIQAKHSSKNGYKQNKLTKHNGYPNHSSNKALKQTTARNGYKQTTARNGYNNHSSKTDTSKPHARKRDNHKANQGSKTDTSKPQLETDKREKNTSKPQLENGYKQNHSSKTEQRKGSKTDTSKPQLKTDTSKTTARNGYKQIDGHRKTDTSKPQLETDTSKQPKTDTSKPQLENGYKQTTARKRIQANHSSETDTSKPQLENLENGHKQTTAQNGYKQTQKTTQATTARKRTTSKPQLENRYKQTTARKRIQANHSSKTIKANTVENEQKQTTARKRIQANHSSKTNTSKPQLERVQANNSPKTDTQANHSSKTDTSKPQLENGHKQTTARKRTHNTADRIQSDHSSKADTSKPQLGNGYKQTTARKRIQANHSSKTETSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLI4</accession>
    <name>A0A423SLI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative patched domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016931</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003140">
        <property type="protein sequence ID" value="ROT65118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLI4"/>
    <dbReference type="STRING" id="6689.A0A423SLI4"/>
    <dbReference type="OrthoDB" id="6505774at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051697">
        <property type="entry name" value="Patched_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796">
        <property type="entry name" value="PATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796:SF92">
        <property type="entry name" value="PATCHED-RELATED, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="44661" checksum="BB1941B33EC1EB35" modified="2019-05-08" version="1">MMTCIDAVLASVKVLVITTASSRYREREKKREKCTVLEKGATGVYGVLEDRKTVRCLELENCATGVYSVLEGRKSVRGRGLVVASRTFLSDDPLGLPRLQALGLVGFESRVLCEEPREARTSEQLPSCCCCLTPACVAESPRLRSIMGCFLEKFDNFLNRCFYRLGQIIANHFGYFIIIPIFITAILATGFQNIVYEDDPEYLFAPTTGGAKDERAIIEENFFLNFSSDFHPSRVTRTGRFARFIIMAKDEGTLLRTEVWNDIMELDRLTHTVGVEYDDKFVRYEDLCGIWDSKCYENNILDLKDLMPEIEAGEYNLTYPLMLNPNTFEMYVFPLFFGGLEISNSSTIESVKALSISYWLRTNTRKEDESQQSSDLATKNLSAGWPRKCQGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLL8</accession>
    <name>A0A423SLL8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003151">
        <property type="protein sequence ID" value="ROT65044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLL8"/>
    <dbReference type="STRING" id="6689.A0A423SLL8"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="367"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="470" mass="50515" checksum="7A6EF56E2FDF28FF" modified="2019-05-08" version="1">MVSLGAPSPPLNRKRSFGLLLSFLSFSGFRPEERILGSGIGVEDPQDQLFFSLLFFFSICGPPSFSAIFLQRAYCLSAPPPPLLPTLQPYPLPPYPTLVASPPPLFPLVPSLPYPRPILTPPLISHFIPTSLPPPIPYLPSPISHTHPSPSDPHASPSPPPYPSPSPPIPDGTPPPCHPLSPPPLHSSTSRPPSILAPLPTPYANPTPPPLTPYANPSPPPPIPVPPPPFHHLSLPNANPSPPPPIPVPPPPPPSIPPPLPRQAIWTHSCCSLTSCLECPWEGTEIFGFVCVAPSQTPTNTKYTYMSPVHGTHPETSSLLGALSSKRDSTYSSMSEYSGRTSPTNSCRSSVGDSVGSGVGSPVGGEAQGHLSFGIQYIPTGSRGATLETRLVITVIEARGLAGKEYLGNACDPYVKVVLWKERRSLRKHKSPPLHVFRTRTVRHTQDPSFNQSFVVEASKSELKVKWKCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNF4</accession>
    <name>A0A423SNF4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016253</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003040">
        <property type="protein sequence ID" value="ROT65765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNF4"/>
    <dbReference type="STRING" id="6689.A0A423SNF4"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000115">
        <property type="entry name" value="Polyprotein of retroviral origin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051320">
        <property type="entry name" value="Viral_Replic_Matur_Polypro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064">
        <property type="entry name" value="POL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064:SF37">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="5">
        <location>
            <begin position="32"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="433" mass="48175" checksum="ED4C39333469A11F" modified="2019-05-08" version="1">MNLTPVPLEIRGGVPVLNFEFTDLPIREFDLPTPPPSAQHHIALPSPMILVPKKDGSFRPVVDYRKLNAVTIPEPFPIPNLRLLLQDIGSGNLVFSTLDLAKGFLQVPVAKESRPLTAFSTHMGHFEFLRTPFGLRNSPLTFSRLMSIVLSGMINDQVMVYLDDILICSPSVSEHEKKLRQVFERLASAGLTINPGKCQFFRSELDFLGHTLTSNGIAPNQNKVQAVIDFPRPQNQKDLKSFLGLSGFYRPFIKDYGSIAQPLTTLLKKDVPFVWAKETEDSFLQLKALLANAPVLAFPDFELPFVLTTDASSVGLGATLHQKVNGKLRPIAFASRTLKPAERSYHTTDRELLAITYALRHFREDPHGRRARAIEVLAEYDVTIVYLPGRQNVVADALSRAPLPSPAELQACKSTPSLLALLNVMKPEPLRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRK5</accession>
    <name>A0A423SRK5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_015094</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002880">
        <property type="protein sequence ID" value="ROT66850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRK5"/>
    <dbReference type="STRING" id="6689.A0A423SRK5"/>
    <dbReference type="OrthoDB" id="10012075at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051170">
        <property type="entry name" value="Neural/epithelial_adhesion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231">
        <property type="entry name" value="CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231:SF253">
        <property type="entry name" value="DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="97"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT66850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="20998" checksum="5D6F8F5CA64529BD" modified="2019-05-08" version="1">MVVLVYFKAEPPASAWKGRARGSAFVGWVKADTKAIQAIHHQVVTHNPRVSVTYRDRTTWNLHIRNVQEDDRGLYMCQVNTDPMMAMMANLKVVVPPEIIDNETSRDTEVKEGDSVKLSCKAKGFPQPVVSWQREGNKGIVFKDLGKTAQRGEEKTGSLTETERSDSQESLLLAAYLCHRHKSGFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STA4</accession>
    <name>A0A423STA4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002809">
        <property type="protein sequence ID" value="ROT67438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STA4"/>
    <dbReference type="STRING" id="6689.A0A423STA4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="710"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="888"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1073" mass="113060" checksum="59BACBED59A92652" modified="2019-05-08" version="1">MLHILAPSSNSKGPEAPINRQGHLPPQRATQTGYRMPPSRHLRRKPPPTGTQQRLPWPPIRGKQTHPQKGRQGLSFRHLRWATTQIQYRVRGKATSKRDHGGSLAPRKANQRGGGRGSLAPPRQLQRGGGSLAPPKATQRGGGSLAPPKATQRDKGLLGTSPRQLKGAGGGLLGTSQATQRAGGSLAPPSNSKGLLGTSPRATQRDGAPWHLRRQLKGTGGAPWHLPKAIQRDGAPWHLEGNSKGGAPWHLPRQLKGTGAPWHLPRQLKGTGAPWHLRRQLKGTGLLWHLEGNSKGGAPWHLEGNSKGRGLLGTSEGNSKGRGLLGTSEGNSRDGGSLAPPKATQRDGAPWHLPRQLKGTGLLGTSEGNSKGRGLLGTSEGNSKGRGLLAPPKATQRDGGSLAPPKATQRDGGSLAPPKATQRDGGLLGTSQVNSKGRGLLGTSEANSKGGGSLALRRQLKGGGLLGTSQGNQRDGGSLAPPKATQRTGLLGTSKATQRGGGSLAPRRQLKGDGAPWHLRRQLKGTGLLGTSKGTGLLGTSEGTQRAGAPWHLRRQLKGRGSLAPPKATQRDGGLPWHLEGNSKGRGSLHLRRNSKDGAPWHSEGNSKDGGSLAPRRQLKGAGTLAPRRQLKGTGAPCTSKATQRGGGSLAPRRQLKGRGAPWHLRRQFKGTEAPWHLRRQLKGTGLFHLRRQLKGTGAPWHLRRQLKGRGLLGTSQGNSKGRGGLLGTSQGNSKGRGLLGTSEGNSKGRGLLGTSEGNSKGRGLFGTCEGNSKGRVHLGTSEGNSKARGLLGTSEGNSKGRGLLGTSEGNSKGRGLLGTSEGNSKGRRLLAPPSTQTQRDGGSLAPPKATQRDGGSLAPPTQTLWHLRRQLKGRGLLWHLRRQLKGTGSLAPPKATQRTGLLGTSEGTGAPFRSNSKGGAPGLRQLKGAGAPWHLSKATQGAGLLGHLPTNSKGRGLLGTFRRQLKGNGAPWHLRRQLSLWRELQLITQDFLTRLGNTHLASSLLVDTPNNRCNTALSTDFPFRLRWPRARLRVTSQSDIVDLGRLVSPAAMAGRRSQARPPTPLSSVFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUA5</accession>
    <name>A0A423SUA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_014136</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002762">
        <property type="protein sequence ID" value="ROT67771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUA5"/>
    <dbReference type="STRING" id="6689.A0A423SUA5"/>
    <dbReference type="OrthoDB" id="1334205at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004558">
        <property type="term" value="F:alpha-1,4-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="4">
        <location>
            <begin position="273"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="4">
        <location>
            <begin position="657"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="5">
        <location>
            <begin position="705"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT67771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="910" mass="102635" checksum="5470799B94530BFD" modified="2019-05-08" version="1" fragment="single">GQSVASEGECAKYSACEWTEGQCHMRANSEAGYRVVSRVEDGGAGFKLHLQKIDPYSTLFDNDAQNLMFEVNYHEDYHVQVKISPRDEERYEVPVPLNLPESPTSTGQMYFVNTSEVGEAFWFSVKRAGSSNGMSLFSTEGPLTFEDQFIQITAALTSSYLYGFGENTHTKFRHRFSPRQTFPIFARDQPVGEGDMNEYGHHPYYVNIDPDTGEAYSVLFFNSNAMEYSTFLLADGRPALTLRSIGGIVDLHFFLGPSLEDINKQYTNMIGKPVFPPYWSLGFHLSRYGYGSTENVRVVRERMKAMGIPQDVQTCDIDYMNRYRDFTYDLDAWGDFPDLVQELHNDDVKLTLILDPALVTDWANYPPGQRGKDRDVYIKWASPEYIPGDQDTSYSDYMVGYVWPDTKTVFPDFLNPETQAWWGDELKLFHETLSIDALWIDMNEPINFNLHLCLTSFILIFYHLTHPPTNGNQTFLHYDVHSLYGWSETVATYKNAGIQPLRRANGGRRHLRLLRRARHGDVRAVDAAGGLLPLQPHSSHTCPYSPHSHIHLNIPLLPSYLPNPHTHPHTPHTYPHPLTLTFTFHPLTPLILYPHSPHFPLTLIFTFTFPSFSLLTQTPLILTLIPLTLIFTFTLLSYSPTHPSYLPSFPSLSPRTSRNHNTIDTADQDPAAWPEVAEISREYLLLRYQYLPYLYALFHRAHMHGESVVRPVFSLSPNDLTALDVDDQFLWGDGIMVAPVVTQGATGREGEWYDLQTGVRKASGPAHSEYVEAPLERIPVYARGGVAIPYQNPFGITVALNATGGASGEVFWDDGDGEHSMDEAFLGVRVFVFAEDTLTMTVAHSTDPVHGLKLETLQFFGYPSNPAGVQVNGVDLPASEWAFNGDVLSVFLSVPLGEDLLSLSLVMCIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUR3</accession>
    <name>A0A423SUR3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_013956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002737">
        <property type="protein sequence ID" value="ROT67920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUR3"/>
    <dbReference type="OrthoDB" id="6330469at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007623">
        <property type="term" value="P:circadian rhythm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007218">
        <property type="term" value="P:neuropeptide signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2010.10">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018251">
        <property type="entry name" value="Crust_neurhormone_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031098">
        <property type="entry name" value="Crust_neurohorm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035957">
        <property type="entry name" value="Crust_neurohorm_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001166">
        <property type="entry name" value="Hyperglycemic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35981:SF2">
        <property type="entry name" value="ION TRANSPORT PEPTIDE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01147">
        <property type="entry name" value="Crust_neurohorm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00550">
        <property type="entry name" value="HYPRGLYCEMIC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81778">
        <property type="entry name" value="Crustacean CHH/MIH/GIH neurohormone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01250">
        <property type="entry name" value="CHH_MIH_GIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0372">Hormone</keyword>
    <keyword evidence="6" id="KW-0527">Neuropeptide</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="92"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR631098-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="162" mass="18756" checksum="DC40E58E2841235E" modified="2019-05-08" version="1">MARKHPCHGDKISPQHPPTAFAFRRAVAEADFAGSLQRQLERKMVVPKALHFDKIFQKRLMLFLVLMICQQGYASFIKVRPNTLREFQFLKCQGEFNKAQYVSLSHVCEDCHNLYRQPEILTECKANCFQNTLFPTCVSLLMLDRHEDDLNKKVALISGQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0B5</accession>
    <name>A0A423T0B5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002499">
        <property type="protein sequence ID" value="ROT69924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0B5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="344" mass="35387" checksum="0595F1801BEB69E5" modified="2019-05-08" version="1">MLSSGCSCVRTCVQGPPNGLYKKLNARRQTQFPHCILRNNSNMKFLIVLALAALSAARPQLVFLVPNTGAGGAPAFASFIFPEDEPAVVAAKKAHFAAVMSALGQGNAAAPAEGEAADAEAAAAEAEAAEAAEVEAAEAAEAEAGAAEAEAAEAAEVEAAEAEAAEAEAGAAEAEAAEAEAAEAEAAEAEAGAEAEAAEAEAGAEAEAVRLLFFSPISTLSLTPFTSSFLPYSSISSSCLFPLTLTLPSHHPLPPLPFPYSFHPFPPPYSSISHPPYSPCPSPPSPPTLPSPHPPYSPLLPLLPPLLFHPLILLILPDPPPPLPSSSCVRPTQELARCRRVSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T168</accession>
    <name>A0A423T168_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_011528</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002453">
        <property type="protein sequence ID" value="ROT70207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T168"/>
    <dbReference type="STRING" id="6689.A0A423T168"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="36"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT70207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21053" checksum="08DAF97D685FB29E" modified="2019-05-08" version="1">MFRSSITRLLGTGAAFSAAAVAGLSSRSQSTLPKVYFDMEANGKPVGRIVMQLRSDVVPKTAENFRQLCTGEQGFGYKGSIFHRIIPNFMCQGGDFTNFNGTGGKSIYGSKFRDENFELKHTGPGILSMANAGPNTNGSQFFITTVTTPWLDGAHVVFGEVVEGMDVVKAIEKLGSRSGRPSQKVVVADCNELKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2L4</accession>
    <name>A0A423T2L4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010967</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002391">
        <property type="protein sequence ID" value="ROT70737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2L4"/>
    <dbReference type="STRING" id="6689.A0A423T2L4"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050260">
        <property type="entry name" value="FAD-bd_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43429:SF2">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="6">
        <location>
            <begin position="8"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT70737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="50257" checksum="C48F0014A64B8A6A" modified="2019-05-08" version="1">MAEVENYTYVVVGGGIAGVTCAEHLYILHPEERTLVITASALIKAVTNVLPLTKTLDAFDVEERNAEYLENQCPNVTALLSRCCGKARCKRTVCLRIFRQKIQIKKLCICTGAIPKVIAEDSPYVMWIRDTESVCQFQARMKGARRILIVGNGGIATEMVYEVTGIEIVWAIKDKHMTANFIDPGAAEFLRSELSKEKSDVTGPSKRRKYTVDEKERVSAVMGGALGPDWHSGLELRGSNQRSVTLETEVEVKEILEPDKFRQSGKELTRLIDWPVYVELTNGKVYGCDFIVSATGVTPNVEKLLAGNNLSVGEDGGLVINEQETKMYMLRGTHAWLGKGTALVSGEEIYMDFCFELFAHATRFFGYKVIILGLFNGQGLEGKYEILLRYTKGMEYIKCVMVDGRMQGAVLLGETDLEETFENLILNQMDLSPYGEDLLNPDVDIEDYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4F5</accession>
    <name>A0A423T4F5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002302">
        <property type="protein sequence ID" value="ROT71380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4F5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="46383" checksum="D12EBD72FD4CAC43" modified="2019-05-08" version="1">MFSPPNPALLQNPPPPPPAPLSSPTLPNDLDTKIPTPRILKTHQHSKGAVIALLRRPRHKHTPCPPARPQCPRTDSLCPRRPPVPRPRPCVATAARPAPHAARSLAHTAHAFVPTPPTLVPTPPAPVPTPPVSLPTPPTPVPTAARIPAHTAHIVAHRPPLYPRRPPLCHATPFPCHHRPPLCPRRPASVPTPPVPLPTRPPCAHPPPLYPRRPPCTHAAHPCAHAAPHTRPWRPAAAKVTGAAASSPPRRECHNKQRSHLVAPRSAAPCPSAAPSAIPPALPSPAAICDAIPPPIFFSCLLSQAVIIAHSSRSHGVEAEPQNPAHPQAQNVPVTSAWACSSGSLAASYFPANKYPDRRHKVACARPATTSIGKKTAEWGTRGDATLVTTLVTPLPLSSPLPRTKCHHHPPTPSNLQYARLASPPRPTSTLQTLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5V8</accession>
    <name>A0A423T5V8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_009892</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01002250">
        <property type="protein sequence ID" value="ROT71775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5V8"/>
    <dbReference type="STRING" id="6689.A0A423T5V8"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006689">
        <property type="term" value="P:ganglioside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF21">
        <property type="entry name" value="BETA-HEXOSAMINIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019179943" description="beta-N-acetylhexosaminidase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="10">
        <location>
            <begin position="30"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="9">
        <location>
            <begin position="175"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR625705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT71775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="355" mass="40054" checksum="F35EAA2000380CC8" modified="2019-05-08" version="1">MYRVCLILLAFATACAIAGFPSVLPTKGEVWPRPQMSLTSSTYMVIRPETFRFTTIGQDCDILKAALKRYIGIMFASYSSVELRSQPWRKDGLFRGYLDNVKVNLIAQCEELPHRNMDEQYEIKIDSPDAPLEGTIISHSVWGILRGLESFSHLLLPSGSAYVLNSTQIMDFPRFSFRGLMLDTARHFLPVSKLKENLDLMAMNKLNVFHWHLVDDQSFPYESAAFPNLSKLGSYSSNHVYSAEDVADVVEYARLRGIRVLPEFDTPGHTKSWGPGQPGLLTKCYTNSTPDGTFGPIDPTNDANYKFLQSFFTEVTHRFPDHYVHLGGDEVSFSCWTLVREGAFVQPGMHSYSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7C7</accession>
    <name>A0A423T7C7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cuticle protein AMP3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7C7"/>
    <dbReference type="OrthoDB" id="6359117at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="153" mass="17028" checksum="0C8A49BA04AC5532" modified="2019-05-08" version="1">MQAYPPRLSGRPGGCLPDASEPPPRVRRPDPVDEREDRGDGNFRYRFETSNGIKTEKVGTPGSKGQSNMQGAFSFPFPEGGVAEFTYVADEFGYQPSSDLLPVPLPSPPTSTDSSRSPSSKGLRESPSRRNDSRRLPYLHRHRKNRKNHLCIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T857</accession>
    <name>A0A423T857_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Myosin heavy chain type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_008946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002125">
        <property type="protein sequence ID" value="ROT72640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T857"/>
    <dbReference type="STRING" id="6689.A0A423T857"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034709">
        <property type="term" value="C:methylosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007309">
        <property type="term" value="P:oocyte axis specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000025">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000009">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052139">
        <property type="entry name" value="Methylosome_Comp_WDR77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46853">
        <property type="entry name" value="METHYLOSOME PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46853:SF1">
        <property type="entry name" value="METHYLOSOME PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0518">Myosin</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="124"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="167"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin tail" evidence="9">
        <location>
            <begin position="331"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="364"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="470"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT72640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="976" mass="110728" checksum="3ECBCB57EACF7BD3" modified="2019-05-08" version="1">MYVLIGFQQDVTSPAGMEQPASHMPCQVDKQLDFITFSKDGHFLMGSSNLTGRYWGGSIWYYDDPSLAPSVEKCLTAYEINSGVVDAAFIDEKNIVVGQDSGTVEFFTVSKSGSGSQLQSVCQIEEHLDSIHCVEVTCNNKSIITGSADMSIRIWDSHTSIVSRLLSVAHSQQVTGLAPHPSNDQVFLSTGMDGNVLLWDLRLQKPASCVYRDWDDKPECVVWTGTGEAGGEGYLVGVQSGAIVLRNTANLSYNITSFQALNRPLYRLAANPERPSQVAICGNDCKLVVADVDSEAIKARYEDERHNDFIRGLAWKDGNTLFTCGWDKATTAEKTTKQLQHQYGEICAKLDEVNRTLSDFDATKKKLACENADLVRQLEEAENQVSQLSRVKLSLTNQLDDTRKMCDEESRGRATLLGKFRNLEHDIQALRDQLDEESDAKGDVLRMLSKANAEALMWRSKYESEGVARAEELEAARMKLAARLEEAEMQIESLNVRNLHLEKTKMRAAAELDDLHASAERAQALASAAEKKQKNFDKIISEWKLKVDDLAAEVDASQKECRNYSTEHFRLKAANDENIEQLDSIRRENKNLSDEIRDLMDQLAALEEAEAALEQEENKVLRTQLELSQIRQEIDRRLQEKEEEFDNTRKCHQRAIDSMQASLEVEAKGKAEALRIKKKLESDINELEIALDHANKANADLHKHLRKVHDEIKDAEARVKEEQRHASEFREQYGIAERRFNALHGELEESRTLLEQSDRGRRHAETELNDAREQINNFTNQNTALTASKRKLEGEMATLQADLEEMLNEARNSEEKAKKAMLDAARLADELRSEQEHAQAQEKMRKALEITVKDLQTRLDESESAAMKAGKKAVSNMEARIRDLESALDEEVRRHADSQKNLRKCERRIKELAFQTDEDKKNHDRMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKTQQELEESEGVTIIHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8L6</accession>
    <name>A0A423T8L6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002113">
        <property type="protein sequence ID" value="ROT72789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8L6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019473873" evidence="2">
        <location>
            <begin position="22"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="42020" checksum="1A4D4A650F3ED6AD" modified="2019-05-08" version="1">MHVLLPPVLSYFSTFLWLASSSRPSDIVKQDARVVVQRQQEEEGVPGPEYRLEKPFQNTRDMREQSSSYKSWNWPEITATASSVCPPAPCSVRWLCLLGGGGAVSPCCCVFFQYSEKQKCKNGRRKDDVREGSGKEGVRGARAEEGAWRHNNHGQREVCRRARETRRRKTLRDFILGLGITPGRSASTPGLGRAWRRRPAGDSGSRATQDSEGRNRGRSGAGSRAGAQAAGGASGIESGSLRRSKRRLIGNDNYHGVPTRARGGRACRALCPETPLGRVRTKGVRGSRRSPRSTALAEVGVVLPGRLRSERAREGGRARQGSGRSKHDAGGVPHGRARRVSIKRPIPLSCRRSRKGRSCACARLLADRLGVYCFTASTAGARLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T995</accession>
    <name>A0A423T995_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peritrophin-44-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002080">
        <property type="protein sequence ID" value="ROT73017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T995"/>
    <dbReference type="OrthoDB" id="6329730at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019417452" evidence="1">
        <location>
            <begin position="16"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="100"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="162"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="221" mass="24044" checksum="A5E221DD4896DF6C" modified="2019-05-08" version="1">MAASLLAIALFVALAVSPSVQVCAPDCTGVDPLTKVRDPTDCTRYYVCVDTSGTGVLLPSIDPVECPDGQYFNDQHTNPRCDPISSAPYDFCSPLCNPCEAHCTHAGEVTPDPTDCSTYYVCLDDGHVLPVGCSAETPFFDFMVGECQTDPTLCFHYCDVCEPHCTQQNERVPDPTDCHRFYLCTPPTMSSFLCPHEEVFNRVTGVCEAGATCITDCPTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAD7</accession>
    <name>A0A423TAD7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fibrinogen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAD7"/>
    <dbReference type="STRING" id="6689.A0A423TAD7"/>
    <dbReference type="OrthoDB" id="6361951at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF327">
        <property type="entry name" value="FI21813P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="1">
        <location>
            <begin position="24"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="238" mass="27496" checksum="9345D02EC28E00BC" modified="2019-05-08" version="1">MVFPPPEHAEPVESSVYKSFVRPPRFEGGYRNCLEIQQKGKATSDGVYIIYPYDRSPQRPVAVFCDMATEGGGWTVIQRRENIVVKENFNRSFLEYGLGFGKPDEDHWLGLDHIHALTNQGHSQIRIDMTDFYGNETWAEYDFFYVGDREKQYALEAKYYRGDAGDSLSFHSGKDFLDNAFSASYVPLGGWWHGRNRKCNLNGDFLDQSKDCDYGVFWSSNNRCHPLNMTSMMIRPNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TB84</accession>
    <name>A0A423TB84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative glutamate-gated chloride channel-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_007797</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001995">
        <property type="protein sequence ID" value="ROT73749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TB84"/>
    <dbReference type="OrthoDB" id="6358867at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="731"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="763"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="13">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="12">
        <location>
            <begin position="229"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="462"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT73749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="846" mass="96729" checksum="355C019778145ED6" modified="2019-05-08" version="1">MLSICQLTLSLHIKLRRVSPYTPLLSYATEHSDNEILIELALQEKAINVICCGELVFEVVNATIELYKWQHICVSLDLSARTLRVLYDNVVGVAARPSSAALLSYLSNVLTAQSTEQSVKVDTTWLKDGQQLEVKGGGRLVVGQEMDSIEGDFDVDQSLDGIVADYRLYDVALGAEEMSDLVNCRSTREQKEPLLDLRNGKLAVKGPSRPLNASEREVCEERDVRFDLLFPQRMNFENAVKWCTNLKSTLSVARSDKDNTYMYDNYVKFSPQCTGTWTNLYWIGVYGDLAGDRWLTPVDPRPIAYDNFIQGWGKPSKKFQCVTMITKEDYKWAAASCLTETCVVCNFTRYPPARLRGLCKESLLERSFHIFEYENNQLVFDGRWHVRIVWINTSWVMESRVHPDLRAWIINEERDVHPVGIHTWEVQGDECEEKQVEMLLTFCSQDEYTCNEGTCIPKDRRCDLAVDCPDQSDEMNCAVIDIPSGYSSRLSPPSLNSNPLPLLISINLTSIKEFNLVSFTISIDAIWQLKWLDRRLQYSNLRGNYRANKLRDFDTVWTPGIKVRDGTMSSVDTVVRSRSLYVARVADPLPDDDTTIVEDDVYSGSNNLLVYEEEHTLTFRCHFDLQMYPFDRQRCSIIFKIQDLTQELCILVKDGPGVVFLGTRRLLEYYLMTETFSNFTQDAVSHVKVELEFKNLYRYYLGNTFLPTLMLVIICCITLCFDLADFQDRIMISLTSLLVLATFFVQTSQSITKTSYLKLIDVWFVALICEDFFIIVGLVIIESLRMKQLEPRLKEVKPFLAFGEKRPAVNTAARVNAAMLVFFTGSLLVMLACFVPVCFNSLNTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFK6</accession>
    <name>A0A423TFK6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001798">
        <property type="protein sequence ID" value="ROT75228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFK6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="419" mass="45008" checksum="3FC5E3D560B9E6B7" modified="2019-05-08" version="1">MPAHARLVPIECQTSAKRDLSPPPPAGTPGRCVFFLLALLISNYTRLLSPFPSSFFLAFSSPPTFFSHLLSLHLWLGTFLLLSLLISPSLPPPHSPLSPSSLYPLSQLLSSAPFLLLLFSSSTLPTHQMCSRSSHAFVPSPPTPTPPPKNLLPCHHSIMHSLYPPIPPPLITLLSPFHIMPTFHLSPSLPRFFLSLPPFLFPIPPHSPHFSFPLPLFPFSSPFPSSPLPLFPSLSHPFLPCPKSPYPPSLSLFQLPLPLPPPQLSPTIPPSPTPAFGSSRSPPQNPPLLFPPTPPASLSPPSPPPNPPPFSLPSPSPNVPLPLSSPTPRLPPQLPSRFPYPLPPPPFPLPNSPSPTPSLPPKLPLSFFPPPPLPSQNSPSFPPVPPPTPPPPLPSPTPSPLPNSPLPFPSPPPPPFTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THG9</accession>
    <name>A0A423THG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-type lectin 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005491</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001709">
        <property type="protein sequence ID" value="ROT75944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THG9"/>
    <dbReference type="OrthoDB" id="6375279at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407:SF1">
        <property type="entry name" value="RE43931P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407">
        <property type="entry name" value="RE43931P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019562239" evidence="2">
        <location>
            <begin position="16"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="82"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="223" mass="24707" checksum="99A59838BE53E5D1" modified="2019-05-08" version="1">MKFLVLLALLAAAAGEHSHGGHGHFPHGGHTHFLPVRHGFRHTTSTFPHRPRPFRPAAHPVAPVHPVVPQPPASGVAVDDRLDDSEYHFSWRHDGSKTYTWDGANQYCRSLGSGWQGISIETREEDSLVSKAISGDLLPWIWTSGHLSRHGLDWAWDSGAQFVGLNWSHTGGNGQAQPDNRERGGEKCLGVLNNFYNDGVKWHDIACHHDKAIICERKARVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIK8</accession>
    <name>A0A423TIK8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001675">
        <property type="protein sequence ID" value="ROT76294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIK8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="481" mass="51314" checksum="7BDB6A47618CB39F" modified="2019-05-08" version="1">MASSPQRLAVLKLLSPDAVLKGRCVRASWQILLLGAAIAEDERDSERHELHSAFYLGLSQRHVGSPAAGDHEYRTWQGHGRCVSVGSGACGPPSLVQMHFWGRECYTAAAACGEARGRQSRCVCQTGCGCPTLPDCCCQRSQTAPYPYASPPMASQSLPYPGALARQAPGSYYRGYTQNYPPAAHCSPMYSITYPDYTPKSDLNQQYPRQAQPPPCTPRQVPPPVAPADRDSALQPDGGDTAHLRPRRSVAGRVQPSSPRHLPCHGANNNSAPPSSRCAPSCTCRPSPRECRACGPGGNRSSFSLRNWASRPAAGHATRVPSRSSSFSNRRGGVVPSSSDDDGALSDTYLAVRINGRRQAAPGYLSDRENGGERVSWAPDVMPGSPRSRQSRVRRSSDSTVRPSEQRGGGISGYESEGEQPTVWGLGGPGDQPRAWGLNLGRAGGVEPQHARFLLDYGFTKVMSGRLSHGVGQAGPAICGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIR7</accession>
    <name>A0A423TIR7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001670">
        <property type="protein sequence ID" value="ROT76345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIR7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="38510" checksum="858263E14185C7FC" modified="2019-05-08" version="1">MISYVATVYLFINPFFLSSVPSDYTFFHYALFRSHPPFPSASLPASSPPYLPPSPISLPPSSLLLSCLPPHPPFFHSLPTFPLPSPLLPASLTSPSSSPPLSLLFLPPSSSPALPSLPSALPPLPPLPASLALFPLPLPPFPHSLCPPPPLPPLTHTLSPSSSTTTSKALPPPPSSSSSSTPPPLPPFSFSFFFFFLLLCLPQPLPLQPSPSPPPPPRLTHQPLVSTAISPTTTTNTTTASSSSTTTASLLLHPPPPATTTSSSSTTTAASSSSTHHPAAASSTSTSSSTTAAAAATTTTSRTAASSSSSTTAAAAATTTSTATAPHNVDCLYEGQFLPISRRGRVSKFYQQYILSLSFVSLGPRSFLLDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ31</accession>
    <name>A0A423TJ31_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sidoreflexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004935</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001657">
        <property type="protein sequence ID" value="ROT76470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ31"/>
    <dbReference type="STRING" id="6689.A0A423TJ31"/>
    <dbReference type="OrthoDB" id="6608471at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140300">
        <property type="term" value="P:serine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF14">
        <property type="entry name" value="SIDEROFLEXIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="326" mass="36384" checksum="52508231CD5A2403" modified="2019-05-08" version="1">MGDQLRINLDEPRYDQSNFYGRLQHFFGITDWRLCVKTDQELNEAKDLLQKYRLGQEPPGTTEEQIWYAKRLYESAFHPDTGDKQNVIGRMSFQVPGGMILTGAMLTFYKSTPAVVFWQWANQSFNALVNYTNRNAKSQLTEQQMAVAYVSATSAALVTALGLKKSLAKKASTLMQRFVPFAAVAAANCINIPLMRQNEIQNGITVCDDKGNELGESKLAAAKGITQVVVSRIIMAAPGMTILPVVMERLEKQAWLRRNPRLNAPFQTLACGLMLTFMTPTACSLFNQKCSLSTSMLSKYEPQVYAAMQNKCGGKVPDTVYFNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TK54</accession>
    <name>A0A423TK54_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004554</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001603">
        <property type="protein sequence ID" value="ROT76846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TK54"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="727" mass="77213" checksum="470C72E60B90EEA4" modified="2019-05-08" version="1" fragment="single">YFFFCSYLPIILFFSSTFHPPFSFFLFIVLFFSLPNFFSLFSFSIIFFHFFFFFISLFTTFRLFLFILYLPPPRLLSLLLLLLSFFLFLPSTLRRSLLLPPRSLLPHLLLVHHLLLSSLSSCSSSSPFSSLSPSTTAATIPSSSLPSPLPPPSPSSSSSSSLSSSSLYSPPSSSRPPGQPPPPPPPFLISLPPSLPPLLFISFLLLSPSSPHPSPSLHSFFFLLLLLPFLLLSLPPPLPPLIPPPPPPPPLLLPSLLPLIPLPPPPPPLLLPPPILLFLPSPLLSPLPPPPLLPPPLLLPPSSLIPLLPPPPPSSPSSLLSSPLLPPFPPSFIPPSSSSPSLHSPPLSASSPFSSLHSSSSSSSSSSSCLLRSSYPRPPTLPLLSPFLLICPLLLSRLLLPSLLLFFFFLPFSPIPLFLPSSSSFPSSPPLPPSYAPSFPPLPLLSPPVLFCSTSSSFPPPSLPPPPPLFLPSFLHASFLSPPLPPSPPPPSSPPLPLLCPRSFCSTLLLFPLLPPFLLPSSFLPPSSHPPPLIPLPFPPLPPPPSSLPPLPLLSPSSFCSTSSSFPPFLPPFLSSPPSFLPPFPPPSSLLPSSSSSSSSSPLAPRSFCSTSSSFPPLLPPSSSFLPSSSPPPPPLLLPSFLLQSPLPSSSSSPSSPSSSSSSNPLPFLTSSSSFPFLLFLSLAPVLFAPLLLLSPLLPPLPPPPPLPPLPPLPLPLAPRSFAPPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLQ3</accession>
    <name>A0A423TLQ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative spidroin-2-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003996</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLQ3"/>
    <dbReference type="OrthoDB" id="6364363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019503904" evidence="1">
        <location>
            <begin position="20"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="150"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="225" mass="22231" checksum="493B64C73DBCEECE" modified="2019-05-08" version="1">MASVIRRALVLALFGVASAAYLGDLQAQPSNQFSSFNGNGGYGGNNGGSNNGGYGGGNGGSTNGGFGGGNGGFGGGNGGFGGGNGGGRGAGYGGGNNGGFGNGGNGFGNGGQNNGGYGSGDPIADLADAIPGGGVPGQDYPILASVPATGFSCDGQLPGYYADTAPEAGCQVFHICQEGGRMDSFLCPNGTVFNQQYFVCDWWSILLLINFILLKLVSHLWCHML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPG8</accession>
    <name>A0A423TPG8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_002940</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001398">
        <property type="protein sequence ID" value="ROT78355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TPG8"/>
    <dbReference type="OrthoDB" id="5987976at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048814">
        <property type="term" value="P:regulation of dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000079">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000002">
        <property type="entry name" value="E3 ubiquitin-protein ligase HECW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000036">
        <property type="entry name" value="E3 ubiquitin-protein ligase HECW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040524">
        <property type="entry name" value="HECW1_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF320">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18436">
        <property type="entry name" value="HECW1_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="155"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="10">
        <location>
            <begin position="1077"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="10">
        <location>
            <begin position="1334"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="10">
        <location>
            <begin position="1596"/>
            <end position="1629"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="11">
        <location>
            <begin position="1842"/>
            <end position="2177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="461"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="615"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="778"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="826"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="948"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1131"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1360"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1410"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1643"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1768"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="615"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="632"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="789"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="829"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="951"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1023"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1134"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1157"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1183"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1198"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1208"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1256"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1271"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1295"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1360"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1372"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1417"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1779"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="2145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT78355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2177" mass="236031" checksum="592119A8A6BAC2E9" modified="2019-05-08" version="1">MGGDGSLPCGARAHVASVVTGNASPRAASAVFLCFAGGARRGGGGVDGGQGGYVGLVERLALCAGASRPQQRGADLRPGESDPEKCLERRPASGESQGHVVWAIDVPAVLPKNVGSVVVRYHSGVEARRACLGSSAVVRVVRLSDGSASDSSEDESLHPSLALQRCLSCTKLLRFTLTNFSAHGLRRGMFFQPDPYVKLRILPGESQTLLPHHGQEARSAVAENTVNPTWKRQDFTFVAYLHDILEVELKDKFAKSRPIISRFLGRLTIQVATLRDRCKAGSPGLLDFPLSSKNTVDSVSGHIYFSVTFAPAASGSGGACTGHGGLECPGEDASMRLTDSAVIESLGPQDLLSNGHMGGYKKSVFPLRAAGNNNNPAINNGVGTGCSADGVVVNGDLMPEDVAANSGEGTDAAGRESDYSPIWKYSCKVPNVTTKPDASEPSGEEAIYETVYPAEDYQSQESDAAGLSAGVSCDSSQPVSDDDSPPPLPPRTKSLLKSLADSGHRPLERSIALYPTVVKKRPMPLPTGTAGEPAKAQTISCTPGKVHNGVNEPSVRPKVGHLSASSQSSCDSESSGASFGEVRRMQCSMEGPFSYDIVDIDDVLQISEFSSNQIDVDSQCQGTKSSTQGPHSSLQSSSCASMESEMSEDIARPSTLQSSLDEASGTSLSSTDNSYKEEACSAVAPLATPEQDCSLLQEAASTDTLLENSEEVLEAEFAACGNRGPYLSRSSTSSEIAASSPASFNHHMPSLHKLARNQSDSVSSPVEDMRECTSLLSAQERQIADDEASVSRESDLTYRRRDSATHGFLRGNEMTIAEEMRMLTSCDTSHQDDTHSDGTDPEGSSAVGPSRKGSTSTRSPSPRLADCLPVSNSASESISLASGSVTCSVSSQQGEEGLTGLEPTCMVVSTESSSSNSVFASPTAETNDLNIESLPSASCSADMNIPREASQEAQTAVAEAQEPSVRPRREAVSQNVSLNEDEDIPPAVPPHKPHHRLLKALVHPPLCPPTPTHHAKPQPPERTTSDKREREASFNAKDDVRERDDKPGSSHHPKLSRQPSLRDWLRRYPKVEVAFDEPLPANVEARKDSHGRIFFIDHVAKTTSWEWPPPKPLSTHRPLFFVPQVDNEKRRSLCDSGESECSSSRTSSRVGTPEPSTPSTPNILGTTGCLSPDHCLGNEGAVAPPPPPPPALSPPPAAAVGGAATALNTSASTPMPSVATSPTTAGLPGATAMLDGSDGDRRRLDEGQEEEEEEEKAPTPRRDRTTGSPGRRPPSPTPPAAVPPTPTHHRRPHHSAGDQDGAIHPERHSRTMRLPSIPERTIKFQRVEIQPGEEPLPTNWEARIDSHGRIFYIDHVNRTTTWQRPSGNDSAQTQRTQSTDQLQRQQLDRRYQSIRRTITSRRVEIEEFPGASSGIFPSSTSTPSLSSPPSGPVATASSTSTINVSSPSSATPALNLSSATSIHNTSSSLPATPSSSGATASSSSSASTTTAATQSSLPSTSASHPQASSCGPSTSTSSSGIERMDMLLQLPAVKFLTRSDFFSVLHMNDEACIVYERSASLRHMISRIRRDPAAFTRYQHNRDLVNLVNQFAYRERDLPSGWEAKYDRSGKLFFIDHSSKTTSFMDPRLPIDAPFVNATKLAVPSAHHRRSRSSGEEEASRVPIPPPRPPTTIGSVCGGIAAHVTPNIPTAYNDKVVAWLRQPNIMDILCERHSGLRTSPALREKINSIRVDGTSALDRLSHDVDLTIVLSLFEHEIMSYVPPMVGISPRGSPQPSPQASPGLPRAAARAPAPYRRDFEAKLRNFYRKLESKGFGQGPGKLKLNIRRDHLLEDAFNKVMGASKKDLQKSKLYITFYGEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNYHEWFRFCGRVLGLALVHQYLLDAFFTRPFYKALLRSPVSLSDVESLDSEFHQSLLWVKDNDITDMLELTFCVTEEICGHVVEKDLKPGGKNIAVTERNKKEYLERMVRWRLERGVSEQTESMVRGFYEVIDPRLVGVFDARELELVIAGTLEIDVADWRKNTEYRSGYHDSHPVIQWFWIAIERFDNERRLRLLQFVTGTSSIPYEGFAALRGSNGPRRFCIEKWGKPSSLPRAHTCFNRLDLPPYPSPEMLYDKLLLAVEETSTFGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQD4</accession>
    <name>A0A423TQD4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed DNA polymerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001350">
        <property type="protein sequence ID" value="ROT78633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQD4"/>
    <dbReference type="OrthoDB" id="6364503at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31511">
        <property type="entry name" value="PROTEIN CBG23764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31511:SF12">
        <property type="entry name" value="RHO TERMINATION FACTOR N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="579" mass="65036" checksum="F2DCD771067BE998" modified="2019-05-08" version="1">MARTACFCENCGQKLSENHLCLLCQVCNIFLRQDYIATASIVTEVALERLLRVQKYLLDTPSHKSSPARPSRCSTFLFRFCTSSSFTAPPLQKTIAAGGPSRPRRRSASPQLGPSRPRCKTPDVQPGPSRVRPERVCNRASKYGDSDSDAEDTYNDNIVETPHIISRQELFEGVCVRLGFSVPDQDQPDPSDYLRVQEEYLADILQTHRQTLGLPPPAAKAFAGFTLVLTRTDLTTGEAREIEENITLHSYIFTSDDDCRRAVRGWSEEMETRLEDWITDEGSGLDLERITAHTITILRVLVPQAIGSMAFMNGSLSSLAKTHIESGLLLKYSKRLILHLPPEAHSLLLTGKGIFPYEYLDDFKKLEDANLPSIEHFFSSLTGETPAEEHDNVLKVWEAAQCRTLSDYADCYLCVNVGLLADVLIEWRSMLLTKYSLDMVNYVSLPGYAYDAFLKMTKAELELISDPLERSVRGGLTTCVRPYTVANNPLVNPSFDPEKKKRSYLLYLDFNSLYATVTSEKLAYGNIRKFSLNEKTEFVVKDLSEHDGSGNISHWIEADIRIAPDVARKTDDLPFLSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQH5</accession>
    <name>A0A423TQH5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_002575</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001345">
        <property type="protein sequence ID" value="ROT78701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQH5"/>
    <dbReference type="STRING" id="6689.A0A423TQH5"/>
    <dbReference type="OrthoDB" id="7609718at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000010">
        <property type="entry name" value="receptor-type tyrosine-protein phosphatase delta isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055470">
        <property type="entry name" value="DUF7042"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45889">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45889:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23069">
        <property type="entry name" value="DUF7042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12 19" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="263"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="355"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="18">
        <location>
            <begin position="461"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="552"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="17">
        <location>
            <begin position="763"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="653"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1021"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="661"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1039"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT78701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1048" mass="114996" checksum="E87962CB59C9982C" modified="2019-05-08" version="1">MAKSKTNQTNELNFALFASLRPVTLVLKPKASKASEGKEGSCESADCPFKVKKASYESADCPFKVKKAHVNQVIALLRRKRKTCVRCFLFEEKHQNYLVYRKSRCQSKQDAASLCESVKNDTDGTAIIKDGGTTVCPFTGSRSFTFQKPYLVCDLDHSKLSSVDNDTQLSFVYNPCPKQTSPNVFPYQERVACVASWSDGDTHYLLGQLTGYNYGGPQYRCHIYEEKPGENYLYSMTRTSAHCGAYSSDYEYFYRIYNESVAPGMPVIEGYDPTKELYLGAPLRLVCRSSGGFPPAELKWFKNGDEIPSESLETKAGSENHIDYRCDAVNFADTLATSIVLFLRPDSELTTTSEPEITTVLTPTPTTRSRHFHGLPDTPIEVTQGASLNVTCAAEGTPMPYVQWVKRDENLHRINMSERVLGEAILVLDGVSDSDSYTCEAESESGFVSREIDVLALGPPPPQNVRLSFLTETQAAIAWDPVEEAKFYTVFKNYSSSQGEAVDVFESTIYTFAGLEPYTKYEFRVAVVTANDQIALSDSIFAITGDTAPDQPTIEGLDAVLKFSVGDTVNLTCSSGGGLSPRVMRWFKDGVEMASAESSSGVELSLVLQEEDDGAELLCQAKNYVAAVNTSVVARIKEVFLFRLALPGPTLQGPLPNPTQSSVSYLSSPSSPVARPPRRHHIHTSTLNVPHDPFNPAQDGYISIITKSFNSAERIECVGTWSEGNASYLMGKLETSSEACAALGESSDSSYRIFGEAVAPGEPTIHGYDASERVKIGSVFNLTCSSGGGFPHAKLTWFKNGEVVPSETFQEAGESAAVVEVTVEGPENETEYLCRAHNFVAGFSASVVVRAEQASQPAFEDIMLPSVSVVEDETAFLPCIRTQEEDTKMDWFDADIETQLTSGTTILADEKTHFQPWNRDGVLGLVVLAGFVDTKYACNVNGRRVGSTRALILARYLIGEGGYEPYDDHLDYTDYHKTVQEGRSVFLNCTIGSNSSSTTGQCVYLPRTHIPRITTKFLLDSKKPPTVNQTNKLFPPENPSTLPKTGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSY8</accession>
    <name>A0A423TSY8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ETS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001716</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001225">
        <property type="protein sequence ID" value="ROT79554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSY8"/>
    <dbReference type="STRING" id="6689.A0A423TSY8"/>
    <dbReference type="OrthoDB" id="5975550at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF190">
        <property type="entry name" value="ETS-DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETS" evidence="4">
        <location>
            <begin position="258"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="355" mass="40849" checksum="0FC2E697BB459EDB" modified="2019-05-08" version="1">MDFSYINVTDTIVYQDSFIECTDNLSSSLTNLDSVDYYTFGIPSEMEGGIFSDMEVFKQLDIARWRGEDCLDWAIDVCRVHGIDQNIVNLMAFRQISGSELMTFSAYDFCRFDTVYGPTFYEEFQRLLETRGLASAGFTPETSDAFVTEENTLFSEGNSDLCDLSPLEPDEDLTDIIQYIDHPASSWDSMFDSDRKEYCDSSYGIEECSIIKSEESCSEFSDDGSIDIPCPSPEPCRVPSADVLGKIRTKSRKRERGPKNWEFMIRLLVDKKYNPELIRWEDQTEKTFRLVKPVIIAQMWGQRANKPNLSYDNFARGLRYQYTTGALKPVPERQLVYKCGPKALKFLKELQREGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT18</accession>
    <name>A0A423TT18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Solute carrier family 25 member 38</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_001680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001222">
        <property type="protein sequence ID" value="ROT79599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TT18"/>
    <dbReference type="STRING" id="6689.A0A423TT18"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="53"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="5">
        <location>
            <begin position="147"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT79599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="235" mass="26207" checksum="E8D4F8731B2C57F0" modified="2019-05-08" version="1">MGMIAIVGRVVRNERIFGLWKGVTPSIFRCVPGVGLYFSSLNWLKTNFCEGQPGALQAIALGVVARTITGVTMIPITVIKTRYESGVYSYGSVREAMRSIYTKEGARGLTCGLIPTLLRDAPFSGLYLMFYTQTKKRVPQIYLEGSTAPPIHFTCGVVAGLMASTVTQPFDVIKTKMQLYPHKFTSFMQAIIYVHKKYGPQGYFKGLVPRMLRRTLMAAMAWTVYEQITKSFGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTA0</accession>
    <name>A0A423TTA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001205">
        <property type="protein sequence ID" value="ROT79679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTA0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="788" mass="89170" checksum="3529237A8A61FC37" modified="2019-05-08" version="1">MSPPSTTQTSTPPQPVHNIHTSQRLFPHSHLAITQTHSHTPSPSLPAQEHFTHCPSAKAHPTNMRAALPIKKQSAFEREQIDILYLLFPRLSIETENARNKLHLFFPHSHTTSHITTSTKHSPPVTNIHTSTAQHHFTTSHKHSPPATKHSHTITNIHHHPQTFTTSHKHSPPVTNIHHQSQTFTTSHKIHHQSNIHTKNIHHQSQTFTTSPNIHHPTNIHHQSQNSTTQTPHHPQTFTTVTNIHHQSHPPVTNIHQSQNSQSPPSQTFTHQSQTFTTSHRHSPPVNHSPPVTNIHHHQSHSPPSHQSQQFTSHTSHKHSPLTTSHKHSPPVKTFTTSHKHSHQSQTYNQSQTFTPVTNIHHHHIHHQPNFTITTFTTAQTFTTSHNIHHQSQTFTTSHKHSPPVTNIHHSHKHSPPVTSHKHSPPATNIHHPVTQSPPPQHSPPAHKHSPPKHSPVQTFTTVTTFTITQTFTTSHKTFTTSHKHSHTQTFTTITKFTTSPQHSPPVTKHSPPSQTFTPSPTFTTSHKHSPPVTNIHHPVTNIHHQFTTATNIHHQSQTFTTSPKHHQQTFTTSPQTFTTVTNIHTATIHHQNIHHQHKHSPPVTNIHHQSQTFHHQPQPFTTATNIHHQPQTFTTSHKTFTTSHKHSPPATNIHHQSQHHRHKHSPPVTSQTFTTSHKHSPPVTNIHHSPPFTPVKTFTPVTNIHHQSKNIQVTNIQHQPQTSHQSQTFTTSQQTIHHQNISPPFTTSHKHSPPVTTFTQSHLPRSLEEAPPSMKIFRSASGFRESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVL9</accession>
    <name>A0A423TVL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ran-binding protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_000744</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVL9"/>
    <dbReference type="STRING" id="6689.A0A423TVL9"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13180">
        <property type="entry name" value="RanBD_RanBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF142">
        <property type="entry name" value="RAN-BINDING PROTEIN 3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="4">
        <location>
            <begin position="329"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="448"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="132"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="476" mass="50135" checksum="FD74E573D914A7DD" modified="2019-05-08" version="1">MGNPFARAASQTTWGSESSDQKPILAPSRLAPPSESGTTKVSSSGLSVIRPSTLGSGRSGGTSRSGASLFTPPTLTVTSSSPPQAAKSAFKLKPSVLSGSANPFAKSGADSDDKADSATGLEEGSSEEPTPSLSGSQDVSSSTSGASRSPQVKQSGERDTPMEEKSSPAASLSHTCTNNFDSSSGTSNTNSSNNTSNSRTLFVPLARNGEGSDSSLSPSISRNSFIFGQNLQSKVVAGDSSVTSSSDSAATTNGENQTGNLFSDAASEISRVPESAATNGRMTTGNLFSDAASEISLPREDSLWNSRQSLAESSRELTEKENSQKRKFDQVEVITGEESESNVLQMNCKLYAWVSGSWQERGRGILRLNDWDAGQEIHSRLVIRTQGTLTVMLNTKVWSDMSVERASSKSVRFTALDADGQPKIFLAMGSPKDVDLLYNSLEWRVAASRSQTNEEAQADSVKKPKKEEGGAESLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW19</accession>
    <name>A0A423TW19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001094">
        <property type="protein sequence ID" value="ROT80659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW19"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="43012" checksum="BC205FFB3FD554CC" modified="2019-05-08" version="1">MTFSGQLLKELATLLDCGRALKTRRARDSSGRAWPSRLALRVGMWVCGTYLLLSLHYLFPPSFRFSSSSFSYSLFTFITFYYPLSILPAALSSLSHSFFSSFFLFFLSTRFLFLIHSFPHSFSSSFFSSSFFSFSFILFLILSLSHSFFSSFFLFLTFFHFSLPHSFSSLLFFFYSFSFSFLLFLQSHLILTFHITLPCSRLPPNSSASSIFFHFLLWLIFLIFFIPSPPSPSSTFSFFLLLILFPFHSFPFNSLPLPLLVFTSSLLIHFLYFSSFFLLPSFLLLVSLSLFFIPSPSILSLFPFSSSLLPSFLSSFSTLSLSSLYFPSSFSPFFPLSPFFFILSSSSSLLSSFLFSFLSFSHSPLFSLPPFPPFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYK7</accession>
    <name>A0A423TYK7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025292</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000957">
        <property type="protein sequence ID" value="ROT81546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYK7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019084261" evidence="2">
        <location>
            <begin position="20"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="42511" checksum="B401B339541EADDC" modified="2019-05-08" version="1">MAMSQVALCHVVVVGLCHAAVVIPIIPPPLCGPVHFFTPAELCCGPVITVSSARELHQLLAISRDSRRAPLDTLASPAPTDPSPPRPQQPPAPSPPRPQQPPAPSLRPAHRASSPSGRMTHRTTSEGKEWGGGKGRGSGPPTTPFGYRLTRRRASDDADARANTGRGEGVSKGGFVYATNEPPGAPRHPSRQKGADHQKGSSCKGKPVSGPAVPPSGRTLIITGRQGYLLVREDRNKTGIECCLVSEDVLGYPEGPPLHYQPRLCGWPGGQLAGPRRGGGGCRDERARAAGARGRGARLATEGARSTPGDEAREDSETASARQMPRVQRGFCHFPRGRARCHSPLRGDLIRPLDRRALSTQLSTPLQSLILVRHSDSSGMASPTKGLCGIGRSCSSCFSFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0D0</accession>
    <name>A0A423U0D0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Facilitated trehalose transporter Tret1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_024660</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000870">
        <property type="protein sequence ID" value="ROT82173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0D0"/>
    <dbReference type="STRING" id="6689.A0A423U0D0"/>
    <dbReference type="OrthoDB" id="6343369at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT82173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41061" checksum="32E8EFD63CE2BC86" modified="2019-05-08" version="1" fragment="single">VYGPGCLFLLRGTGHLRCLAQPRYTGSPEAQCHRVWHSDDLFDWQLDMLGSMVSVGNIPGTWLWGFLVAAIGRKRAIMLLVVPYTLGWCLVALAVNPAMLLAGRVVHGLCIGATFIAGSTYIIELPDTAVRGALAALPSLVLSTGFILTTGLGLVLRWYEIAIVGVGVIVVQTCVMSFLPESPSYLAISGREEEAMRVLRDLRGPSVDVGELLRILKESNKASAKEPLHKVMRNPAILKSLATVLTLFFVQNFCGLMVFYVNMTRIFLEAGSTLDESVATILVFLVQAVGTALACLYLDRFGRRTCLMFSLAVMSVCLLAMGAYHFLSGNEGRESYTWVPLVCLMVYMFASSSGTGPIPSILNSEYYPTAVRSQGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0R3</accession>
    <name>A0A423U0R3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000851">
        <property type="protein sequence ID" value="ROT82280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0R3"/>
    <dbReference type="OrthoDB" id="1877767at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="289" mass="32558" checksum="0F03DB2AC76FF550" modified="2019-05-08" version="1">MSSPATSLKSSQVSHAYPPPPPPHFTSHPLPLSLSSLPLRGRKAPLASCSLPLTCRSLVSVKNSVFLAPSPPLSSKNFCCATPASSNNKQNININKQENNKYNTQNERITNPKASIQKDTPNKEAQDKNKNKSTCWHPFAEQSLPRKSFLLQFPFRRAKVVSSSSGTSVYTMSREELGEDLETIKRQQAETRLRLSLANRHISTLYSQVQDLEVQFKTAIKHKKHSARYNLRQKLAVIMGLKIVYLNYCAAKSQELERINQTLERFIGRQEEAMDTDTNEEPSLSMLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1V6</accession>
    <name>A0A423U1V6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alkyl transferase</fullName>
            <ecNumber evidence="5">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>n isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate = a di-trans,poly-cis-polyprenyl diphosphate + n diphosphate</text>
            <dbReference type="Rhea" id="RHEA:53008"/>
            <dbReference type="Rhea" id="RHEA-COMP:19494"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:136960"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.87"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01000789">
        <property type="protein sequence ID" value="ROT82689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1V6"/>
    <dbReference type="STRING" id="6689.A0A423U1V6"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1180.10:FF:000005">
        <property type="entry name" value="Alkyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="321" mass="36917" checksum="7F7A2ED0B89CCB52" modified="2019-05-08" version="1">MTWLVEKNRSWAEWAVARILRVGPVPRHLAVIMDGNRRYARKEHQDTLTGHTRGFHKLTEVLSWCRDLGINEVTAYAFSIENFKRPRHEVEGLMDLAAEKFAEVLEELEKLAKHGVCIRALGNLTLLPERVQQGVAEAVLATKDNDKYFINLAIAYTSREEIGTAMSELCRGVSEGQLQASDISEELLEKCLYTGGTRDPDLLIRTSGEVRLSDFLLWQSGFSCLFFTKVLWPEVTIWHLFGAIFYYQRHYHTLAEARRESLNVRQCMVEESDIDVCHAKFGEKVTAEHIAAQTCSRTERTDAFLKELYEKRINYLKKVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2J7</accession>
    <name>A0A423U2J7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SURP motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023899</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000759">
        <property type="protein sequence ID" value="ROT82914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2J7"/>
    <dbReference type="OrthoDB" id="5836667at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040397">
        <property type="entry name" value="SWAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019147">
        <property type="entry name" value="SWAP_N_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161">
        <property type="entry name" value="SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161:SF15">
        <property type="entry name" value="SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09750">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01141">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="118"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="152" mass="17256" checksum="46B34E6CC76458D9" modified="2019-05-08" version="1">MGDSSLMVDRYDVRGALYDLKEAESGGGGDRWEGLTEEERAEEEKCDQERYLALYHDEFQYQEYQDEEAKRLISELDLTPIHTAGYFPEADEDTFVPPPDLNVPPGMIVPETVKQNKIIVKTSKFIVTQGGQMEIVIKTKQAGNPMFSFSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4A3</accession>
    <name>A0A423U4A3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000673">
        <property type="protein sequence ID" value="ROT83535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4A3"/>
    <dbReference type="OrthoDB" id="6375098at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.70">
        <property type="entry name" value="Designed single chain three-helix bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="116"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="49319" checksum="73AE4AB4A99575F2" modified="2019-05-08" version="1">MVSSSEDPDSGPGTGDEAGENGRGKVDGSGQPSQPQQRSRVDRSQGEKVSTERKIKTTETRRETITTKGMHDLSSAINSLDDHFQAGLQEVRNSLASIHQERNTLTEHLRSVSEMLVEVSGEKNECQNVISDLQQEVSSIRDQLTNEQRTNAVLRKKIHEMENENESHMQSIASQLRDRQLAHRSIVKWRRKVLERGHYSVVRLLEEENSQLRAELLKCQEAAKQAFLRSANALNSEAITMFQKPTRGIVIMDYTRPVSFVDLDADPALSEEEMRAEDWPLLLPQAGGTDTRPIAAPGPTPLVSSQLTPPRTLIVSPCRPLPNQPDARVLRLLISPAWSEHVAWVHQTFDHPPQSCLCSLTYTYTCIIASSCTTLPSCFQPRSHTCPLQKAVDSLNSQCASLAARLNTIEARFDAIESRFDILAASLADLSTKLATNDTTLVSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U606</accession>
    <name>A0A423U606_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase DC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_022705</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000591">
        <property type="protein sequence ID" value="ROT84129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U606"/>
    <dbReference type="STRING" id="6689.A0A423U606"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="7">
        <location>
            <begin position="121"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT84129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="175" mass="20357" checksum="72EF8DE642485E6D" modified="2019-05-08" version="1">MVTQVTSIFTKSPNPFRTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLAGYPPFFDDNPFGIYEKILGGRVEWPRHLEATAKDLVKKLLTQDRTKRLGNMKNGAEDVKRHRFFKNTDWDEVYHKKLKPPIVPKVSYEGDTRNFDDYPENNWRSTQGVSDIELAIFSDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U616</accession>
    <name>A0A423U616_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000587">
        <property type="protein sequence ID" value="ROT84151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U616"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="45364" checksum="B8484BFF962FBA4B" modified="2019-05-08" version="1">MEAKRKFSRLAGLVRPEGWRGIRGPDVQGHGLRGPGGAPYSREAPHPVVQPSIDAIVNLPLYIAEKNRRRFFQQVGKAADKFNMKLARPHADNLVAPFLVKERKSRPRLRPAHGGLRSRQEAPADAGSDPSGLAATDEGQAAPGIWLQTPSREDEPSESSALVGKAKDRALMLKKLGETEVRSLRRPPRHRPAHYGKAIGKCARCHQGAGGARPAGRAQVALVPPGEHPSRGPRRCHREGGSHAAKAQEEFGVKLRTKSREHPESGRGASERSREGRGLHRAPCCREAPPEGGARREELRGTFPSASSPAGSARPSARRDEHILVLGPEGCRAAWIEREFGVRFVRPSGNMPLVLEGDVEAVTGAEGPPRATGRRPALCQRPSLLISAHGGTTRDGDGRTKRPAFLTFRLSDSAETGNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8J2</accession>
    <name>A0A423U8J2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_021558</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000454">
        <property type="protein sequence ID" value="ROT85017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8J2"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045596">
        <property type="term" value="P:negative regulation of cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002373">
        <property type="entry name" value="Protein krueppel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001498">
        <property type="entry name" value="Zinc finger protein 404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000912">
        <property type="entry name" value="Zinc finger protein 660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050331">
        <property type="entry name" value="Zinc_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515">
        <property type="entry name" value="PR DOMAIN ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16515:SF58">
        <property type="entry name" value="ZINC FINGER PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="260"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="316"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="216"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="413"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="490"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="598"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="224"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="422"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="619" mass="66618" checksum="6AEBE9DC9E8552E3" modified="2019-05-08" version="1">MKDGGDSDKDPGSGALTHKAGGPDLGISLGAHLGATRHLSGGHHHLGGGGGGLPGFPGLHHPLQLAALSSQQQAAAAGMLYPSLLGPNLSPATLMASLAAARSTHQFLGGQPPSGLPPVLPPTSGTLASLHATLAAADTSRQRDLLATMAAADSLVPAAPRLARQAGLRRGVGAPRQLGVAGVVLFVQRDRRVPSLAPPLSHPNLIGASLAAAATTGGLGSEAPSPTLGSSPPGSNGRLDPYTSTTPARKASAGRPDRVFTCKICNRSFGYKHVLQNHERTHTGEKPFECKECHKRFTRDHHLKTHMRLHTGEKPYHCTHCDRQFVQVANLRRHLRVHTGERPYACELCSSRFSDSNQLKAHMLIHKGEKPFECVRCSGKYRRRHHLIHHKCPNDPDSDKRVEAIQYSETTFAESDTYSIGPEEEEEEDFPEEELAPPATLLEEEPLQLEKRRERKSRDPRRVISHPMSGLMNSGRLADAAHLLRGLHSTLPEQTEPEDLSVASTRRDRNYSGMSAVSSVSGGGPHAHAPARPHGTPPRCCVPPIARRPAPLVGVERIFIYRAPGDERGAVPVLFYPPPLLTPPSFLVSIRINQMTGSLRPPSDSHASLTTRISLPNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U954</accession>
    <name>A0A423U954_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein 91</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_019495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Early endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Late endosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat WDR91 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000357">
        <property type="protein sequence ID" value="ROT85238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U954"/>
    <dbReference type="STRING" id="6689.A0A423U954"/>
    <dbReference type="OrthoDB" id="193023at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141039">
        <property type="term" value="F:phosphatidylinositol 3-kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051898">
        <property type="term" value="P:negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056327">
        <property type="entry name" value="ARMC9_CTLH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039724">
        <property type="entry name" value="WDR91"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13083">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13083:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23138">
        <property type="entry name" value="CTLH_Armc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="ARMC9 CTLH-like" evidence="9">
        <location>
            <begin position="203"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="537"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="413"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="871" mass="94737" checksum="20837238F94555EE" modified="2019-05-08" version="1">MPLLSLFPYATSPVSPLCPSSLTPSPCFPMPPPLFSSLCPSSPPPSPPSLFPTPPHSILPLIPLLRPSSPSLPIPYAPFLYSPPYAPPPSPPLPISLRPLTLFSPSSTPPSRPLPIPVPLSPSSPPPLLPPPLVILPLPLPLPLLPRSAERVNMSHIQYLDELVKEYLLFRGFSQTLRSLDNELKIDKDKGFRVDRLVDQVVSHIQTYDLVGLRELWAHLDKRIFAHLPHTLLPCVRKLETSILRLYVVNTIQTNKPDKLVEFFEKMAQELQSQAEWREWFILPYLKGVEENSSFAMYFTRQWQDTLLVSLHNFFAVVFQSIELPTLASYRDEASKIARLQEDNELLRARLSALTTSDQPSLEHLVVPDPPPPSHLMDDFYNIAQEAPSSESQLKSLKTILFGLGGGLPTSPILGRRATGGAASASPQPSPIAAQAPSSNNHGGTSVFTHSVARRTSSQAPAEEKKRTRSSSVASMSSSRNSGEHIPVKRLVQTSASTTRQSRSPTKIRPQEDPMSSAKMEVTSDKASFLLLGQEEYSEHRAVVTHAVFNPSGTLVASADTDGVVKLWSPSPSPKTQSGLVVKSAVTALEWLPRGERFLLLATKAASLRLYDSRDKKTVWETGPDSCPVLKDQRIMGVRVSPGEGSAVISVAPRVRPQGTSTPPAPPSLHTIDMKSLKIESSYRLDGVVVNGCIMNHNGGLLVCGCNDGSVRIIDLRCPDVIASWPAHQGEVFTVRLSPQENNIYTIGSDNRFACWSMAQTGARVMDHVLHDRAAGPFLVGVGSGGTGRSVLLRPYGPLFALHQDGEHVLTCSPSGPIVYKVCENGLEQVLQVGGHKSPVVTVDWCNALQCGTSVAAALDGSVTVATLMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB28</accession>
    <name>A0A423UB28_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">26S proteasome non-ATPase regulatory subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_003956</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000153">
        <property type="protein sequence ID" value="ROT85916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB28"/>
    <dbReference type="STRING" id="6689.A0A423UB28"/>
    <dbReference type="OrthoDB" id="261572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000017">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="789"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="9">
        <location>
            <begin position="5"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="8">
        <location>
            <begin position="806"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="859"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="955"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="860"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="990" mass="110749" checksum="71D428186E831BED" modified="2019-05-08" version="1">MGFITSAAGILALLDENEDQLRVFALERLNEITDTFWPEIADSIQKIEKLEENGEFPKRELAALVVSKVYFHLGSYLDSLTYALRSGPMLHQDRNQLYIDTIKVHAIDHYIKLRAQKDAKMDARLEELLNNMFKRCITDQQYRHAIGIALETHRMDWFREAIMTSDDIVGSLTYSYKIAMQYIEQRKFRDEVLEELVSLYQGLETPDYVNMCQCLIHLDKPHEVASILDKLIKNDSLKSEAMDNELMAYQIGFDLYESATQDLLSHVRQGLRTTAPVPSLLKDVDAVTSTTSTSAAPAEGSTSGANEDEEMATPQTEEENADTAMSEEKTLDDLTELEKTHQNRVANLARILSGEMTIEQHLQFLIANNHTDMLILRHTKEAVRASVCHTATVIANAFMHCGTTSDQFLRDNLEWLSRATNWAKMTATASLGVIHRGHEKEALTLMQAYLPKESNSPGYAESGSLYALGLIQNGANIIEYLLNQTKDATSDIVRHGGCLGLGLAAMGTQRTDVYEQLKYSLFQDDAVTGEAAGLAMGLVMLGSANEQAVSDMVNYARDTQHEKILRGLAQGIALTMYGQQDQADRLITELSEDKDAILRRAAMYTVAMAYCGTASTPAMKRLLHVAVSDVDNDVRRAAVEALGFLLFRSPDQIPSMVSLLSESYNPHVRYGAAMALGVACSGTGQKESLGLLEPLTNDPVNFVRQGALIASALVLIQQTESTCPKVKDFRQLYAKVIGDKHEDSIAKFGAILAQGIIDAGGRNMTISLQSRTGHTSMTSVVGMFVFTQFWYWFPLAHFLSMAFTPTCLIGLNSELKMPKMQFLSNAKPSTYGYPAPLEEKKKEVAEKVTAVLSITAKAKKKDDERKKKEQKDEKMEVDEEKEKKEKEEKEKEEKEKEKKKEEEKKKEEPTFDLLSNPARVMKAQLKVMRMAEGSRYTPVKELNIGGIILMRDMKPEDSEELVQPVPALGPKTEEETEPDPPEPFRYVDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQ64</accession>
    <name>A0A3R7LQ64_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vitellogenin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004146">
        <property type="protein sequence ID" value="ROT61470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQ64"/>
    <dbReference type="OrthoDB" id="6484170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="825" mass="90870" checksum="FD6D92B7900C514D" modified="2019-04-10" version="1">MEGGSACRNWSLETASYIREGSQSGQISEHISALRLTKGSKDIISVEATHTIEGAFPENIIIKNEATVDIGRSSYKAIYDVIYQAEKVGASMEVVRTGDNEKIVKLDAIYHHSGAEYSTNFLLKVPTYMKPLKIQAKIGEEAEGRYMLETAIKYGQRMILEANGPIMARLSSKIAKMQANIKLSALASEPYIIGANVVFGNKKQVIAMEIKEREEPLFGVEWKMVQESSEKTTVGIAFVLPALIENKVDAIITEELIHVNFNNLVLPNTSSRRRVKGFTDVNIAEKRANVEFSWDADNAPEKKLVLDASLISSPANPGHAEIHGNVVIAGEPYHAKLILTATDLIEHMEGENGFKLILTTPSQKTVVVGASCDVQLAGATTKVISTVEYKNVRDRKYKYTSVIALERLGGPLNYAVEAKVTYKQPGTAEIKVETTAKHHWTPEEHVVAFKVAAEAPVLKTPAMIAFSIHNAPNAFVGVCKIERTAPFTAFEWNVQVTPEGGIEAVEAGVDMKAIIEVLKIVRAIATLEEESYETYGPHTAQYQYRFTRPSPTSYTMQMRTPTRTMEGRAKLSPRESGIKFYPNKGKTESKYEIGYKVNHEGRWAQRASKLEVRMNHPVLPKPIMAAAQYTVAEGTMRGTIELDIFPEEADKITGTVETQRISENAIRAEAFLTGRMLKVNPKAIITAAYAPETVALDVVFHKTPSAAPIFAIAAKYDKTAAHSAAATLTVKMEERPVFEMSAVTEPEEPATCNGIRMNAVAYAAAFGKYNVFSKMCRPAFIEVTAMRPGGAKETLPSLASDTLTLLKQAYMWRVLERVAVLLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRY3</accession>
    <name>A0A3R7LRY3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003553">
        <property type="protein sequence ID" value="ROT62779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRY3"/>
    <dbReference type="OrthoDB" id="6379691at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="578" mass="65080" checksum="6CFE8D81431B2492" modified="2019-04-10" version="1">MQNFKTIFPSAKAVSVSWIPVAERHVRSPASTYLSRTPLPSAGGAVACGCPGTNQVYVLHKAPMTGWYTFVPGEEGFQLVVNLEDEAKVEYKLVYVRTRQAWVIKEIRSPMVNDLFTWNSTGAQGDGVNNVKIFCPGPCRCRKVKVRGERCFRGYYGRTDVVEQLKEEETARLEQEALAKALRTTKGLSLLAPSPRLLPTTSMTGEDALETLFRQMNGKDNRNLPKVKIQSPSTSPRKSLSRVKRFSLPGQRDRNQRANIDNLQGLLAGQFNLGHDGAGLQNGRKKGWQDERRIDQVDNTLDEQDGDRHMFDILLNDQQDDQLNRDQKDLPNGRQVELPNDRQYPMLSNWQGSRQEDQRDARPNERKAAAQNEQEDDALTRLLFAQSQVRQRDSYPLLSSRLPKKPAPKNTLQETLDMLNKLSECVLSPPETSSSATERPSKSCAAGTHPVSAKVKPKPPPYGPDTRRTRRNLNLTILQSFNNLHIDGQDSEVVEEETVKCEPDVYAYMGNAEYKITRTETGHFWWIGMGNDLFAVSDEGGPCLDQLPAHTKWMTAVDRNAVKNNENVTVQCVDWDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVP7</accession>
    <name>A0A3R7LVP7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Orcokinin peptides type B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003046">
        <property type="protein sequence ID" value="ROT65739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVP7"/>
    <dbReference type="OrthoDB" id="6093641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005184">
        <property type="term" value="F:neuropeptide hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040384">
        <property type="entry name" value="ORCKA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33864:SF1">
        <property type="entry name" value="NEUROPEPTIDE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33864">
        <property type="entry name" value="NEUROPEPTIDE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="14453" checksum="EFF810797FEF2895" modified="2019-04-10" version="1">MGFAKRNFDEIDRAGMGFAKRNFDEIDRAGMGFAKRNFDEIDRAGMGFAKRNFDEIDRAGMGFAKRNFDEIDRAGMGFAKRNFDEIDRAGFGFLKRAFMPRSNLFKRNFDEIDRAGFGFNRRSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXH7</accession>
    <name>A0A3R7LXH7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malate dehydrogenase, cytoplasmic</fullName>
            <ecNumber evidence="2">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020297</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003951">
        <property type="protein sequence ID" value="ROT61883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXH7"/>
    <dbReference type="STRING" id="6689.A0A3R7LXH7"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000010">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="MALATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="6">
        <location>
            <begin position="4"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="14028" checksum="69E4E16FCF3800CB" modified="2019-04-10" version="1" fragment="single">AEPVRVCVTGAAGQIGYSLVYMVGSGAVFGPETPVILHLLDITPMMNVLNGVCMEISDCALPCVRDVIPTDDPAVAFKDIDAAFLVGAMPRKEGMERKDLLAANVKIFKTQTKKSSYFTSIFGCGKVFYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZB3</accession>
    <name>A0A3R7LZB3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002652">
        <property type="protein sequence ID" value="ROT68627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZB3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="40580" checksum="E274FDCDADB02C11" modified="2019-04-10" version="1">MPLSLSFLASPSPLLLPLSFFSPFLLSLSLLPLLSSSLSRPSPLLPCLFSPPSPPPFLFSFRPSSPSFTPSPSLPSLSILPPSSASFSSLPLPYRPPLLPPPFSSPSLSLLSSSPPPSLFLPSPLSSFLALLHPSLFSPLLSLPLSSPPLPPFSSPPFPSSPASFSFCHLSSPLSLLSSPSLPLSLPPSPSALLFLLLLCISHLLFSSLPPSLLTSPPLPSSPFPFPFPLFLSPFSSLLRSMFLALVVLLCFSPLYSYGIHSVGSLLSLSRLLFSSLSLFSSLPPPSPLFYSSFFSLLLTSPLSFSYLFLSLLLSFLFPLSWCSIPSISLSDLPLLPFPLFRSVSTLPLSSPFSFSSVSRFLSLSSFLSPLFLRFSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M189</accession>
    <name>A0A3R7M189_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002612">
        <property type="protein sequence ID" value="ROT69032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M189"/>
    <dbReference type="OrthoDB" id="6371112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1118" mass="127635" checksum="70A3709D63CECB36" modified="2019-04-10" version="1">MWGPRAFVDSGSKRDPAEDRDSRERRRRSIRHRLLVEVGHSCSLPPWSDSDDDDLSDRDYERMVRRRLEREHRWFGRQWQPPRLVSPDAQEEEEVVAADEVVDVGSVVSDARLYEAMEKMDSGEVATRFLLQMPSSVPPELQGESPAGPSEANSYNILMADVSGSMGSYWAHVVSGWNTFVAPRLRGRTDLYVFGSYVELLRTGSQLEKSDFTGGQTDLTGALQTIVDKVYTCKEKYIKVFIITDGDHNQSPDPPNTVISQMTEPFGKVCDVYLLGAGTGFPVEYSLSIRSRLHNGSANLPTLFWANDTSGVEEQMDAISKNLAKMNERSMKLSVPGWKLPGAESKQDFHVLEWVYFPEDPAKHGHIDVSLHKYKGQLTPERKKITCDLLGKALRQWNSVAVQFHSVGKEIPPDLLPLMERLFYSNLHTETEGYSVAAKLARANHKTVEVEFRTTMNKIKEILTTEKHRDALRLAENILSTTVTAGKYEVKSLQLKGHTEYDYGRDCQAFERLYHEKKPELKALTVTPEECCRITMSSTLSDLQDDAFLEMLNMNKFEFLKNFTMSGIPVFSPTRDSVSLNPWSYNIVRILRSPYTTMSQVAIESYASNSDPGTRHKDIKLKEDDDNTHFNAVIPVFSREAAKVMRPFLQTRLYAMCATFAILKNPHIIDFNIHLAALATCWVRILYDHPEVPRPEYVRLREESIIATASQYMHRRGHVDYCDLLRDDAPQALMTESEVKIKNRPVKCESLIKPMFMLYILKRNDELEMTEVEQIVRLILVEFIGRNLSHSSNSQKDSTPYTDFFLAEKKEDFFQNYSKDVRSTILQAESSAAFPLSKFYTLEEVQKEAKRKSKEQMKAVRESLSLPVRVSMEKVERLFNPSLAGAVSWRTLRTYAGEVGLPEEVVEELFSEKSAFVYTHHALRYSSSKQRLLAKIDSYENAFMYVKSQVEKENMGLLVKTLLNDLVSFYENAWLAEYRQAHADVVRPMSKEEILAEAAARGVEVTAATFEQVYRKYRPHLGLLTDACQCPSCPFFLKPNKRYNQHAIVERRKATLFPHGFHQVAYDCREGGLESAISEFQKGTHRKHKGQGKSLPQEAISPLLQEMEQLAVIYSGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2I2</accession>
    <name>A0A3R7M2I2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">non-specific protein-tyrosine kinase</fullName>
            <ecNumber evidence="5">2.7.10.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_011731</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
            <location evidence="1">Focal adhesion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002485">
        <property type="protein sequence ID" value="ROT69985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2I2"/>
    <dbReference type="STRING" id="6689.A0A3R7M2I2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005925">
        <property type="term" value="C:focal adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009887">
        <property type="term" value="P:animal organ morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008284">
        <property type="term" value="P:positive regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13190">
        <property type="entry name" value="FERM_C_FAK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000004">
        <property type="entry name" value="Protein-tyrosine kinase 2-beta isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041390">
        <property type="entry name" value="FADK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049385">
        <property type="entry name" value="FAK1-like_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041784">
        <property type="entry name" value="FAK1/PYK2_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000299">
        <property type="entry name" value="FERM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46221">
        <property type="entry name" value="FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46221:SF9">
        <property type="entry name" value="NON-SPECIFIC PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21477">
        <property type="entry name" value="FERM_C_FAK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18038">
        <property type="entry name" value="FERM_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50057">
        <property type="entry name" value="FERM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0965">Cell junction</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="FERM" evidence="18">
        <location>
            <begin position="776"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="68"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="116"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="426"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="551"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="359"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="600"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="717"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT69985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1157" mass="126784" checksum="E7DC657EE1E2142E" modified="2019-04-10" version="1">MPLAPSEDARRDPLLDEGAGVAAETPTPVLVHSTSHLLSPLVSGVGGASRHPRGGGSVSTPVLQLASATRRGGHDGAGARSPPSTAVSMHAGSRDSHLLPGNSYFFQRDAGVRHSVSSSNRSTISQNSCNSVSFTPDKPPRPTSGRRADFISRGSVAPTPTGKDVAKTNQKNSGLRSFSQSTRNFLRGGGGTSDTSGTPVLKRSQSVKAGSGFCRPQGTARGDVRESQSVTSNHPADRRSQRQDATNAYGIINGMKQPTAKESPTTPFHFFRRSSVRDSQRTPSERSSIRSKTNSGPSHIPEPSWRSRGTPSTPGRSSGDSARPQSIDEGTVSRSWRRQSAESRQALQRNHSTRVLRDANSQPGGQGSRGQTRAGSGPSELQYARIQTGGDKGAGKQKTKLLQQCKCGMNSYCDQCRSSMKASKEEVSKCPSATSKENSFARNSVRRASASQRVQTEKPKEGAQPASAALERRPSVRKAVETYEQLQSVRRERDRLQNRPTALYIPVDREQDAEDDTGRKDIKEYLLEYDEPGRPISVAIDELMARSAVAPQLPKKRNLSPPAEEAKKRSHRGAATASAPHMYARAQTSRAKSADAASSGVLQTTRANRQPKTTGCENGHHWHRKPGPAVSRKPATERPALMKTLDASSYEEESLEEVMRALEAEHRMRTLQAEESSEDDFVDLDEILVDYDLPGRPSARPRRGEDESLGCGLSILPSTGSSAGLRSSTPPPSSAIMSSGFTNAENVSPLTSPFLAQENGGVGVSPRLGSPERPEKSIKVHFNTSFNVVKFGDGTDVKGIINVVIGRQAAGPRPYESMFAIRLRNTITGELHWLHQDLTMYQVEEKFPDYQSEEWRFELRVRYVLSDLHQLYDKDRTTFCYYYEQVKNDYLEDEGRGNEGIDQESAIQLACIEIKRMFKDMNGSTLEKKSNLEFLEKDVGLHKFLPSSVLNTVKPKTLRKSLQQHFKKYGQLSESECFFKFLELLGKGRKYDQESFRCALGSGWSIPVTLLVGPSVGISYTTDSASKPHHMASFEQVQSVETLTTDCDTHRKALVQLKVAGTAEALTVTCPSIIAAESLADLIDGYCRLVNNTRTSLWNTKVHIWKSLPCPCQTPQGSFVCSCPYFPFCGPWTVHAVAFRRVVIALVAFVFFISPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M553</accession>
    <name>A0A3R7M553_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002057">
        <property type="protein sequence ID" value="ROT73166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M553"/>
    <dbReference type="OrthoDB" id="6377675at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="363" mass="39906" checksum="6252AED01B93CB49" modified="2019-04-10" version="1">MPRRKCKYRWLPMVIVYTAETWHHRIALEVVLVKVEYLHAGRWLWVHHLPNSPCIPLCPKHILAERRPKIPSTRALLNPRSPSPSRPAVPLPPAASPPGQGRSKVGRTLPTPAVGGRSSPGHSRLAVSSAHKPGTLRTMWKEVLLVGFASVVLQAPQAQSAAESVPFPGYLPGENVRAKAPEGDGGPNDIYAHLPVRRPELDDDQVVIYPHSLVFEYGQDPEHHIYEVHSAKELANLAHSKHDKHGKHAHDHHHHDKGTKEAAAKGTPKNLKPAPPRGSHEQNPELPILSFRHVPISSSAGVILRYPSPVLECDALTMPFARNSILAQTPYPRLPPSACHIVTPSLPSQVLYPRVLPLTPSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M707</accession>
    <name>A0A3R7M707_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hemocyte kazal-type proteinase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007734</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001988">
        <property type="protein sequence ID" value="ROT73800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M707"/>
    <dbReference type="OrthoDB" id="192611at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="11"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="61"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="112"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="160"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="4">
        <location>
            <begin position="210"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="261" mass="28500" checksum="EF8D30D6337C29B2" modified="2019-04-10" version="1">MKPPASHPSPLPPFDACSRECPFTLQPVCGSDGKTYSNECELEVAACRDPDVRMLAMCACLMDPKCNRQCTAEFDPVCGSNGITYPNHCTFDIATCNNPTITKVRHGRCDNQRECATTTCQQPYDPVCGSDGKTYENDCALEAKICVKPELYKVANCQCAPECPKAECTREYKPVCGSDGVTYVNDCLFDNARCRDLSLRVLRSGECDSDNCDLKQCTTDYQPVCGSDGGTYRNQCHFDVAACKDAMLVKAGDGECSSVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M789</accession>
    <name>A0A3R7M789_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-tubulin complex component 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_007519</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001955">
        <property type="protein sequence ID" value="ROT73987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M789"/>
    <dbReference type="STRING" id="6689.A0A3R7M789"/>
    <dbReference type="OrthoDB" id="5860513at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF14">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="7">
        <location>
            <begin position="224"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="6">
        <location>
            <begin position="498"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT73987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="856" mass="96700" checksum="E279ED21F8EEC834" modified="2019-04-10" version="1">MTHRVTSHFQLAVNLLNEGWSGAAAKDHNVVADKIRRRLVREKRLEDAARFSGLINKLMKSEVPRNKASILSFFLALSQDNTSLSSTRILTLSNAQSPVHENGLTNGHQTEEAFPIPKLFHNVDACLSPTAPSGARVPPGVNSLPSLNVQSTRHGGADITSGSSRVSRLAAMYKGAATANPDSPFAELQQQAPADRLQFAQNSHKQSTKSTKEELIEVTEKVLIREVLFIFQGIEGKIIKMDVNKDGFRLDPKVRLSLSQKELIMKLTEVGWLYNQVKNFCEWGGRGTGSERTTDRTAAGLVNQSLVMALREELNEYCRLIAVLEAQIQEGGDTPMGEPMGGLTLRRLVLWTLEPRTHLKALALLTHAAREVYGGACVSAIYQHMHHGDPGHRTVVRHVLNMACTPLYVMLTQWLLDGTLEDPHHEFFIASDHTVSDDKLWQDKYSISKSQAQKVLASGKSLNFLRNVCHFRAPIAGRDAIKSALQQTTEEILTRHKLMDHLRALRRYLLLGQGDFIHYLMQVLTPELGGPATYLYPHNLSSLLETAVAASNAQYEEPDILERLDVRLLEISPGDLGWDVFSLDYHVDGPIGTVLTADCMRQYLMLFNALWKDKRMEMILSDIWKEQAATSKLCRDLPELGVVLHGVQLLTTEMVHLVHQMQYYMTFEVLECSWHGLMTNLKSAQSLDDVIAAHNEFLKRIVAGALLDSKSKQVRTHLRTFYNLIQNLRGLQERLSLAVSAEVNARKNAEAEIKAKTEAGEFGTTAEQQDVEKRRRKEFLTKVVPKLKSDLRINTQTYQDMVQSFLLMLSQHDDQNLHLLCTRLDFNEYYHRRDHRLNQRLTYHHKRKSMGTSFCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7A6</accession>
    <name>A0A3R7M7A6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative organic cation transporter protein-like isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006633</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001840">
        <property type="protein sequence ID" value="ROT74876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7A6"/>
    <dbReference type="OrthoDB" id="6348391at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="575" mass="62593" checksum="11DF089BED0C0F6E" modified="2019-04-10" version="1">MAKRLDDVMSRLGTGRWNLLHISLPLLLLLSDHVPHPGRRLPRPRVDYTCRRPEGAHDAAAARSASPLFIPAGDNTSEEAKPECSYFVLNSSSGQVEEEPCVEWDFDNSTFSSTVGTEVIFDSDRLFQLACGWEYLRSTYQSIYMFGVTIGAPFNGVLADRYGRKMTMAVGFVAYSALAIGSCWIPNLSALLLSRFLMGAVDPTILKTGYIYTRHGGRGSQVAHAYRHCIVSAMGAWSHGVGRVRLPRPGMADASADRVFAVSGLLAYSVFMDESPRWLAVRGQHRRALRVLQRAARWNGVALPRGRASAPAQGRSQGRDARATPREAGSEGTILILLLHHSPTPSHTLAPSPNRTPRLRTITLSLYTNYLLVGAVYFGLSLSGGDLSSDPFLYMVLTGVVELPAYTLVIPLVARYGRRAPVVAFFFMGAVALLALPFVPTGSGESMTLALMGKMSIASAFQILDFYSSELFPTEGPLYPWAPSAVFGAASVLAGLATLALPETLHVPLPDTIAHLEEREIRTRYGRKMTVAVGFVAYSPGHRLLLDPQPLGSPALALSHGRRPPHDTEDGIYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8R2</accession>
    <name>A0A3R7M8R2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002463">
        <property type="protein sequence ID" value="ROT70137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8R2"/>
    <dbReference type="OrthoDB" id="6344716at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT70137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="49962" checksum="84FD49B021E71F59" modified="2019-04-10" version="1">MPSTLWNEYAEILMDEAVKRFRYREEGKKYFERIMDYTFCGKLTRCSTSAIEGCSSGLEETLYRKLRCCRKLESLNMTIVPRDDAGLSTAMLSLQHLQHLVTLALLPPARYSFHWAVKAIGRHCLKLRELKIVYNGDLFSEGEGIADLQRCRCIASLWLFNFGRLCETKGVGCLLRTLTHLKVLFHKELPNAILEMTSGRREGMLQACEESPGDMQVLMKEPSLPRLIGPPCLSEIVRRLPQLRVLVLQQASLASSLGSTLQDVDVSALTVLRVSDVWDVNHDLVSAIARSCPALQVLSVASSSLEARGQLVTPPRRAPFPSLREVTLVPSALAGRPALVTPSAWQLGTALTRYVLDGALRLAFVRLHFKDSDVAPEDMPSEPDLEAVLCRPALRDLSLEWPPAASPTLVERLVEACPALTSLAAITTWPLSPRQCADVIASYGRRIDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9U9</accession>
    <name>A0A3R7M9U9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane-associated protein Hem</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEM-1/HEM-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002360">
        <property type="protein sequence ID" value="ROT70995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9U9"/>
    <dbReference type="STRING" id="6689.A0A3R7M9U9"/>
    <dbReference type="OrthoDB" id="548214at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031209">
        <property type="term" value="C:SCAR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030031">
        <property type="term" value="P:cell projection assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030866">
        <property type="term" value="P:cortical actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048812">
        <property type="term" value="P:neuron projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019137">
        <property type="entry name" value="Nck-associated_protein-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12093:SF10">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROTEIN HEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12093">
        <property type="entry name" value="NCK-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09735">
        <property type="entry name" value="Nckap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1116" mass="128307" checksum="74D1CDCED811744E" modified="2019-04-10" version="1">MSRNLSPTQQKIAEKLSILNDRCVGILTRIYNIKKACGDAKSKPAFLSDKSLESCIKHIVRKFPNIDSKSLQALTNVRTDIMKSLSLYYYTFVDLLDLKDHVSELLTIMDALAMADSLDINVSYDLTKGYLDLVTNYVTLMILLSRVEDRKAVLGLFNAAHEMVNNQGDPSFPRLGQMIMDYETPLRKLNEEFVPHGKLLSVALSSLWVLYPRRNLRADQWRAAQMLSLVSTPSQLLNPAQTDVMPCEYLSLDTMERWIILGYMLIPQTLQKQAALECWAQALQTGWVITLFRDEVLHPHSYIQSYLETKKELSKRTSDVKESYSHAVTHAPLMHRERRKYLRTALKELALILTDQPGLLGPKALFVFMGLSFARDEVLWLLRHHENPPLQKVKGKTADDLVDRQLPELLFHMEEIRALIKKYSQVLQRYYIQYLCGYDAIALNQLIQSLQNLPEDESVILSSMCNEIGNLSVKQEEGATFDFRGIRLDWFRLQAYSTSNRSGLHLKDHRELTALINQIVFHTKMVDFLDEMLIETSDLSIFCFFSKQFEDNFHMCLEFPAQNRYIVCFPLICSHMQACTHEICPEERYHIRERSLSVVNMFLEEMAKEAKNIITTICDEQCILSDKLLPKHTVPLLIHKKKEKKKKKEDTTEGRPGFESYRKTREELTTMDKLHMALTELCFAINYCSQIQVWEYTFAPREYLYQHLEQRFARALVGMVMHNPDTNEIAKPSELLASVKTYMSVLQTVENYVHIDITRVFNNVLLQQTQLQDSHGEKTITAHYNTWYSEILLRRVSAGHIVFSENQRAFVSLTAEGAQPFAAEEFSDINELRALAELIGPYGMKALNENLMWHIANQVQELKKLVILNKEVLLSMRTNFDKPDQMKELFKKLQQVDSVLSRMQIIGVILCFRQLAQEALADILDNRIPFLMSSIADFKHHVPNGDTMLVNEMSSAAGHPCEVDPALVNVLRSHKNEVPDEEFIITCLLMVFVAVSIPKLARMDNTVYKPAYGAHANNSHCLAQAVNTLFAALFTYCGRAQDIEERLKEFLALASSSLLRLGRENDKDVIKNRDATYILLHQIVVQSPFLTMDLLEACFPYALIRNAYHTVHKAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MA95</accession>
    <name>A0A3R7MA95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001555">
        <property type="protein sequence ID" value="ROT77211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MA95"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="47440" checksum="28FE84C9EC230868" modified="2019-04-10" version="1">MTPDTRSSKYTTPSSRTPCAVSTPVGTLCPSCSLPFACCLVQWLFVGVGGAEESPRGRSRRSPRGRSRRSPRGRTRRSPRGRRTRRSPRAQKKPAGQEDQKKPVEEARGAQKKPAGQETRRSPRGRRTRRSPRGRRTEEARGAGGPEEAARAGGPEEARGPPRAQKSPRGPEEARGAGGPEEARGQEDQKKPAGQEDQKKPRGRRTRRSRGAGGPEEARGAGGPEEARGAGGPEEARGARRSPRAGGPEEARGAGGRRSPRAGGPEEARGQEDQKKPAGQEAEEARGQRTRRSPRGPEEARGAGPEEARGAGGPEGPEEAPGQEDQKKAGPEEARGAGGPEEARGAQKKPAGQEDQKKPAGQAQKKPAGQEDQKKPAAQKKPAGQEARGQAQKKPGQEAEEARGAGGQKKPAGQAPAGQGQKPAGQGNPAEDKTPHVPPVETPLPLRRPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAK3</accession>
    <name>A0A3R7MAK3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004798</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001634">
        <property type="protein sequence ID" value="ROT76613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAK3"/>
    <dbReference type="STRING" id="6689.A0A3R7MAK3"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11054">
        <property type="entry name" value="CYP24A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000006">
        <property type="entry name" value="Cytochrome P450 302a1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050479">
        <property type="entry name" value="CYP11_CYP27_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279:SF120">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="778"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="794" mass="89855" checksum="BF0D99D5B97F27AB" modified="2019-04-10" version="1">MNFGPSLGPKPGPEKREKNRKRETPQQPRYGGPDDKERRTISVWWLAQDAPARGAGGSVRTQLRRRKNAREGTTKDPRNFEHAVRKEEEKRARIPKETKDPEATSSSKTNSTVTRRKRSLNATTRSSASVENPPCSSLDSILYWVALTVGFFSLSLVCFAMCRGPRHTNPTLTNHRRRGSWTFFSRRNSRKRSGRASSTEGNVGSVYSKEDDENSFFEIVAVYDTLHDAPGNSVSPDPRLNCDDNRDATEVLENVTHDVTSAVHNEDLDNLTTHPIVIRLEHSLHSRSVIHCLAKVFCARFTSSYTMVLLVKKRALLASLSRRAVISRCLGSSSIQEQLAVPLEEEIRDAKPISEIPGPKSYPVVGSLLTIMKGHQFDKMAAHKFYLHMRDTHGHIYRMTVPIAGNFTVVSNPDDCEKLLRVTMHNPQRLPLDSIKAVREETVDGFFKENTGLLLENGEKWWRVRSKVQTPMMKPKMVGAYLQQMDEVSREFTDRIAQLQEEHGEMPSDFQFELYKWALESVSLVALNRRMGCLNPDVAQDSETVRLIGIVNGIFQALNDLEMGSMLWRLVRTPTYNTLKRRHGEFLEIAMRNIQETEAAILAEDPENERELSLMETLLLTEGLTRKDVLTLILDMLTAGIDTTSHTLGFALYLLARNPQAQAKLHEELDTVLGDHQGPLLPKHMAQLSYLKAVIRETLRIFPIAIAMVRILDQDAVLGGYVLPKGEKVIYPNMIAAWDEHYFPRAKEFIPDRWLRGRPLGPIHPYASLPFGAGTRMCIGRRIAEQEMSCNASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC68</accession>
    <name>A0A3R7MC68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001454">
        <property type="protein sequence ID" value="ROT77947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC68"/>
    <dbReference type="OrthoDB" id="6368529at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="42881" checksum="A20FC1625CFABC87" modified="2019-04-10" version="1">MDLDYENVTPKWRVLEQDLASRNKVKYKRVLDTFREKLREFVKQHIAENKIAKQNSEGRHVGPQWLSFLADLGSNAAQKLDANQTENLQESGQSGPGHEPPQSASESSAPRQESSDAPKARSETSKEPGGGRTEGRQRRLARDAPGVMYLPVQSGSSSCPSYADTVASSLTQMAFASMVVTVFNAVNVVLPPPIPGRKRQVDLKRKRRHILQLKRISGKLREMQGSRYALVDKQQKGPAGGQGDGAGGECMSRKAHARAALVTLSVVKSLLLPPGITSRGSGLEGDRQEAQDIPHWGEDTTRSHRLPPFAETGIRRHRFLQMKDQYNVTICSLQHLCNFIGSSALQEDLVSHVTLMSRLRDDIMPEGVFAGSGTPIPVTCSALKPLCPAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEB2</accession>
    <name>A0A3R7MEB2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001241">
        <property type="protein sequence ID" value="ROT79461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEB2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="75860" checksum="ACAEB169F09F07B5" modified="2019-04-10" version="1" fragment="single">FPKTFAHVTSITSPHGGTSCQTPASHRSLSLSFLSLFPLLHPSPLLIFPFFPSLLLTFLPSSVFNLSLSFHFLFLLFILPLFLTFHLSPLLYLSPFFLFVFSLSLPLPLPLLFFILLLYLPCSLSSSYLPPFLCSPLPRSSSFSPFLPLPPPFLLFILPLSLPSPSSSLSFPPSSFSWFSSLYLSFFLLFILSISLPSLSSSPSSPFLSSSSPLPPFLWFPSSYLSFFLLFILPPSPSSFQASLSLPFPPPFLLLFILPPFLRFPSPYLLLTLPPFLLFNFPSLFFLFPSLPLPSPSSSSFPLPFFKVTLSPFPFPSLHPSLSLSPLPPLHPSPLPLFFMIPLLLPFPLHPLQASPFLIAPHPPNLPSSSSSSSFPIPLLFMVPLSFPSPFLPSKLPPSLSPPPLSPFYPLPLFFMLPLPLPPPHPTHPPPPPLHPSPYLVSSLAKMSLHIPALQRERPIHSTFPLQLPHATLTHYIPPSTSHVTSSLDLPSPIPLSPSLLPLSSSLLLYSPPHSLNPHSYLPPHSSIPPHSISPPHSLYPLPLLLSPSHSFYSLPTPLLLPLPPLPPSSLPLPPPHSLYPLPTPSIPPPLLLLPSHSSLPTPPHSLYLTPYHLPSPRLFLSFLYPTLLLPSTYYTPLSSSSRIPTPLFTPPATSFLSPSFLSPSFSSPTLPPLFLSPPPPLSSFLAPRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEP9</accession>
    <name>A0A3R7MEP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001900">
        <property type="protein sequence ID" value="ROT74413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEP9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="494" mass="53879" checksum="3B5C9BD43B3ED29C" modified="2019-04-10" version="1">MCLSVCLSVFLFLHFILHPLSLCLSPFPFAFSPSLVLLVSLFLSPSPFPSLSSSSSSSVYLPFLSPSLPLSFSSSPSSPPHLPFLHFLLHLLPLPISLSFSFFLIFSLFLSLSPSPFYLPSSSLSLSFPISLFFIFFFIFFLCLSPFPFTFSPSLVLPVSLSSFPFPSLSSSFSSSVYLPFLFTFSPSLFFPLPSPHLPSSLSSSSSSPHLFSFSFFLIFSLFLLPLPNLPSPSLLPPHSSSFFFSHLLPLLSLFPISLFIYSSSPSFFLSPSPSPSLLPPLLPLLFTSPSRSPSPSSFTFFPSLFSLSFNLPFPSPHLHSFSFFLHPLSPSLHLPSFSLPSSSSLPSTSSPLSLPLFLPLLSSSLSPRLLSFPSPLPISLFFPTSSSSSLSPVSLSFPSFPFFLTSLSPRLFPSPPFPFFLIFSLPSPSPSSLILFSLSSLPLPSPSLSSNPDFYRYFSALRFLLTVVVCGGLIVSCLSFSFLCLACFSLFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGZ3</accession>
    <name>A0A3R7MGZ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020647</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004108">
        <property type="protein sequence ID" value="ROT61556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGZ3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="81758" checksum="32AD311C122F5443" modified="2019-04-10" version="1">METTIRHSPTFPHGKLPYAILQHSYMENYHTPFSNIPTWKTTIAILQHSHMENYHTPFSKHSTWKTTTFSNIPTWKTTMPFSNIPTWKTTIRHSPTLETTTFSNPHGKTTITPFSNIPHGKLPLQHFPPWKTTIRHSPTFPHGKLPYTILQHSHMENYHTPFSNIPTWKTTIRHSPTFPHGKLPHAILQHSHMENYHSPFSNIPTWKNYHSQHSHMENYHSPFSNIPHGKLYTRNWENYHKHSLMENYHTPFSNIPTWKTTIRHSPTFPHGKLPFAILQHSHMENYHSFSNIPTPKLGNYHSQHSHMEKLPYAILQHSHMENCPLGKRFAILQQGKLPFAILQHSTWKLTAILQHSHMENYHSPFQNSIPTPFHMENYHTPFSTHFSTWKTTIRHFSNIPMENYHSPFSNIPTWENYHTPILQLFPHGKNYHTPFSNIPMEKLPFAILQHSHMENYHTPFSNIPTWKTTIRHSPTFPHENYLTPFSNIPTWKTTIRHSPTFPHGKLPYAILQHSHMENHHTPFSNIPTWKTTIHHSPTFWAILQHSHMENYHTPFPTFPHGKLPYAILQHSHMEKLPYAILQHSHMENYHTPFSNIPTWENYHTPFSNIPTWKTTIRHSPTFPHEKLPYAILQHSHMENYLKPFSNIPTWKTTIRHSPTFQHGKLPYAILQHSHMENYQAILQRYILPTFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MII1</accession>
    <name>A0A3R7MII1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000676">
        <property type="protein sequence ID" value="ROT83503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MII1"/>
    <dbReference type="OrthoDB" id="6372844at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="436"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="365"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="497"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="581"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="674" mass="73746" checksum="CC86085B33436CBE" modified="2019-04-10" version="1">MATFPEKRTRPSTQRQSWFIGLAVVVFVSLPRTTDAQGLQDYLKLQATVSSHTQSLLILREYQTLTDKIWKWYLDIQKGKERDLAPSSSSAGRSRLPEASAQHQDLQEQLFSLQKQFEARFDSQKAETQQLKEELDSQKLQSRRLRHELSTQKEVVARLEDVFSKRTWSLEEQLGELSDQLERERNATQTLKQQLESAVVESLATDARAAEELEEQVGEGRSRAELEDVLMFVKNVVVSANRSLDDLHAEVKRLRDEKIKALTSDLASLSSRQEGDRRTLSEHLRGLKEEVRVLNQSSSRGNEAQLERRLASFDARITGLSTLDARLNGRMSKLEGRAQGLQSAVDVVRQRMNAVDAAVGALRQAGDVAEKLASLEDANRNLDNRLHVAVDDVKRRVSYLEQQAPPGTEGTQGLQEKEDLQVQGGLRADREMQDTEATLGRPGAGGLKDHAGLQAREGPRAAEEPQGTEELRVKEEMQETEATLGPLVEGERKDHAGLQAVEELQAAAEPQGREELQAAVEAQGREELQAAAESQGREEPQGREELQAAAESQGREELQAAAEPRGRGALQGKEERTVAEAPRASKGRAGSRAGEASRGRRAGPACGGASGCEAGRARGGRRGSRGRRGSQGIQVSQGREVSRALKAQGATLGPLANAPGRGHPVLGSSACVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIK2</accession>
    <name>A0A3R7MIK2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003853</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001518">
        <property type="protein sequence ID" value="ROT77485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIK2"/>
    <dbReference type="OrthoDB" id="6358005at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="62"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="376" mass="42716" checksum="EAA9F6B21C88132E" modified="2019-04-10" version="1">MEQQSSKIQQLEASEERLRANLRNNSRSSDGARISDLLDRLIETENSELKLKERVWGLERSEKELQIKLMEGEKMNQSLRAELRDQEELVHRLMTLETENNALSAEINQAKDSARKMSEVQQNESYLRGRVEELEMTENMLRETLQQADLILAQREKKLRDQVSSLQEEVQSYKAQLESAASKEHGARECEVSYKKQLEELKARLAETERQLRESSSETNSQETQHRSEVTKLRNQLKLGNSQLNELERLNCELRDRVLAAEAQSEHLAKELEEQCRRHEQDLLTLNLQVSAGESHVKELQGQLEQLSHEHAASELDVLAASPIAPLYATITSLITALKSCESCSETQKSTLAEVTAQLGTLASCSRAGPVTPTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJN7</accession>
    <name>A0A3R7MJN7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_018657</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003438">
        <property type="protein sequence ID" value="ROT63445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJN7"/>
    <dbReference type="STRING" id="6689.A0A3R7MJN7"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10780:SF18">
        <property type="entry name" value="LD43650P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10780">
        <property type="entry name" value="MITOCHONDRIAL CARRIER HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="124"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT63445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="315" mass="34876" checksum="05A6359A3B6D4016" modified="2019-04-10" version="1">MSEKGKKDELTWMHVIVRVFLNSTTHPIEYAKVLIQLGHEPLEPYKSRTVFGREALYYPSVFGYSDCAHKKRDGFLGCYRGLTPKLAANIVSGVAFQRVTENIQFKELDGEVNIEELNMKQRTQRFLQNTARESAGRAAAILVSQPFHVIAVRSMAEFVGEDGQYVGVFTSVGVIYREQGVKGFFCGLIPRLLCDLAALWLGKTLAHVINNYLVEDKDLKQYVSASMNFLASALTYPLQVVSNCMAVSGSGLVAGSPPNMPIYDGWIDCYRHLKQIRGLKRGSSMLWRAYTGPTIMLGGSPAIATNSMFVAPASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKZ0</accession>
    <name>A0A3R7MKZ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-terminal amino-acid N(alpha)-acetyltransferase NatA</fullName>
            <ecNumber evidence="4">2.3.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_017620</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-alanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-alanyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50500"/>
            <dbReference type="Rhea" id="RHEA-COMP:12701"/>
            <dbReference type="Rhea" id="RHEA-COMP:12702"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64718"/>
            <dbReference type="ChEBI" id="CHEBI:83683"/>
            <dbReference type="EC" id="2.3.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-cysteinyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-cysteinyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50512"/>
            <dbReference type="Rhea" id="RHEA-COMP:12707"/>
            <dbReference type="Rhea" id="RHEA-COMP:12708"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:65250"/>
            <dbReference type="ChEBI" id="CHEBI:133372"/>
            <dbReference type="EC" id="2.3.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N-terminal L-seryl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50504"/>
            <dbReference type="Rhea" id="RHEA-COMP:12703"/>
            <dbReference type="Rhea" id="RHEA-COMP:12704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-threonyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-threonyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50516"/>
            <dbReference type="Rhea" id="RHEA-COMP:12709"/>
            <dbReference type="Rhea" id="RHEA-COMP:12710"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64739"/>
            <dbReference type="ChEBI" id="CHEBI:133375"/>
            <dbReference type="EC" id="2.3.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-terminal L-valyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-valyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50508"/>
            <dbReference type="Rhea" id="RHEA-COMP:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12706"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64741"/>
            <dbReference type="ChEBI" id="CHEBI:133371"/>
            <dbReference type="EC" id="2.3.1.255"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-terminal glycyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50496"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133369"/>
            <dbReference type="EC" id="2.3.1.255"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.255" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKZ0"/>
    <dbReference type="STRING" id="6689.A0A3R7MKZ0"/>
    <dbReference type="OrthoDB" id="25586at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990190">
        <property type="term" value="F:protein-N-terminal-glutamate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000101">
        <property type="entry name" value="N-alpha-acetyltransferase 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091:SF4">
        <property type="entry name" value="N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT64437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="177" mass="20499" checksum="5E42B6339B29CA38" modified="2019-04-10" version="1">MNIRCAKPEDLMHMQHCNLLCLPENYQMKYYLYHGLSWPQLSYVAEDDMGQVVGYVLAKMEEESEEDPHGHITSLAVRRSHRRLGLAQKLMDQTARAMVECFNAKYVSLHVRKSNRAALNLYTNTLKFTISEIEPKYYADGEDAYAMKRDLCSYALQNDITPADASTFFDNKKNEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLM5</accession>
    <name>A0A3R7MLM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001151">
        <property type="protein sequence ID" value="ROT80125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLM5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="138" mass="16031" checksum="217B87F892094AE1" modified="2019-04-10" version="1">MCGHGAWSQVKGAAAQKRQQYKSFVLSYLNDNEGPQRRDQILRDIKDQEKLTKDERNSLDQVIDSMIENAIVSLKYDEEQRECIELCDLTCTITKEKRKSPNASRKEQAVQTSQTRWTAPAIVVIKQQHDVVLRRQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLV4</accession>
    <name>A0A3R7MLV4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_000945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001130">
        <property type="protein sequence ID" value="ROT80328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018611640" evidence="3">
        <location>
            <begin position="28"/>
            <end position="1957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="492"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="659"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="854"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1378"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1428"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1517"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1649"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="893"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="930"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1396"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1454"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1685"/>
            <end position="1696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT80328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1957" mass="205319" checksum="E02A3410E055A7C7" modified="2019-04-10" version="1">MYNVQTKIRPFHIVLALVLVNLVCSAGQSPLGDASHGAFGAHERIRAAPFAAESTAATSGVPLQVSQAEFRVSFPPKTTDGRDAASGRGDTSNAVGLIGSTGAEDHVPYVSQSAPSAPHSPMQASMRVQRRGAQRPRRNPQHFSAPLGSASPSLLRPASLPSRAQPPADVRATPSESSGISDRKAPTNPHRSGPRPGAGQVRGAHGVLTGYGGQQHVLSRGKEAAARADPYDLLSAASPSRSARPLSRQHLSALTARDNAANLLPTATSARASLFGRLAESHAADPLPVGHFPLSQQTTDGKALGGSQHAGQARVTMVTHGQVVQPGLAFRKISTREYQSPPHGRMRQPQRPEAEAGADEQRSPNLFPRNNPKTGLRGANFQIGRGKNSSKGSTDIPKVRNSFLRQSDSLNPLSFTGQPSGSLSGGGRPGALTSTSLANVHHRNVTYVDLSAHTDASRIPGAQGRPTPPAPTYEAGGPVSPAQLLLQTLDARPVAPGRPPSSVIARPSPVNPEELLGSTEAPPVTLSFLRNLTDASENQEAPPKPIDPSAVQVGGAQGGQDLGPSPFFSGSPLRPQYVFTTPSPPRAPVDPASLLIAPGFTTRPPITIAPPGYNPLLDNLQKLDIVHVNAEPSPGGVDIPSPQDALSGLDAELPFQAQPPYLPNLAERPRPQEPQIPGKPPSAVSPEGPLVISNNTLVEGQGTAPILDLIDNNIAFDVLDQISGLSVGASAAPHVTVPGFQGLQSSQSPQQLLYTKRPGLQPQQFLPNNPVLNVPQPTNNGYFPQNPAYSANPYDANFQPFLSNDAQMSHSLPQQVNLPPRNPNTPVGYPNIPSAGYPNIRPDYPFPLNPHWPYGQPQPGDGLPQVPGYGVPFRDPNGHFPYPYPPPQGASDLGSQGATGQGTQPSASVAASVTNEFSSADSAAEGGDGVVSTSTTVVKGGSSTSNNNFYRPSPGVGQGTADAVPAGGARPTEVEPISRRPRPPIIVDGVHNRTATPSDIFPDSNVNVACSRRHGCPAFILRKRPSEPLPGDDGKLTYIFDEAPPLATTIGEGQLLEAIGLVLDLLNRTEGLDFEDDATGLTGDFDYIFQGAGVEGFDDLLSHTPGLAPPINPQNIRPGLQIRPVAVPSTTPSPLAQHIGLQKRPNYEVVRVPENTVLNAPSLPNLLDNKRVFSVNPILTKSPEDASDPGSGLLGQPGSFELLRNKLVQAHLETLQEDGHGVTSPDPLGSHVSEVGSLADTQMGGALPAARPSLAEILNLEQQSIPDEPPLVPAREPEGDHHHSMMRHVMAATFMGLPMTTALMTALGAPVALLAPLGLAIPALLTMGCKLTEHGKGRPGGASKDSRLRTAPSLCEQHYATSASLHFSWLFPGLGGGDEATSTTQAPAHSDTRVSHGGGGEGLRDGGGFAGALRRLGGVFPMMASRIASRMGGRRRRAAEEELSRGVPAAEAGQSESDPASASLSAHDLDTLRDLSLFYSSLSGNNATDVEKPSPDEVLMHRKYLLGLLKQLRGQKQEVLPSQSARLPPSTAGENSTFVPAKGEREEAAATPAEGPGSESLGSHSISGGVDRIGQVADAADIQNLDPSAAALLLHQFQTQGSLNLLPPGLLGQAPPTTPPPTHFDLLYGQQQPEQQEASVEGHLVGAAAAPSLERSPPRGEAKRLASGAEGPSPHHLTPASAITSSAQPSQSANQSPLPPPASDSPEGLPEILPVPQYINRSPSLQAEALPHPSLAVNAFGHPFFDTSQLPLGTDLDLSANGEQGSFLFPSSELLPMSPSELIHDRVSQADADGFAKPEFYPNYETLAEALQLLQRLNALQASPTLNRVDLGASTYLDQDPSILPAPGSSNLDYLYDQDYLQYAALSNPVPNTRLTTEVNDAFSTLAQNLADAISTFLTDIGTPSPRSRHCSSSASSFASSALSSLQLSVEALETLTWTILLQIENFEKRNQLPTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPC3</accession>
    <name>A0A3R7MPC3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="21">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_015254</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 21">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="21"/>
    <dbReference type="EMBL" id="QCYY01002901">
        <property type="protein sequence ID" value="ROT66704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPC3"/>
    <dbReference type="STRING" id="6689.A0A3R7MPC3"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000010">
        <property type="entry name" value="alpha-1,2-Mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 20" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 21" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 21" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="24" id="KW-0430">Lectin</keyword>
    <keyword evidence="12 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="18">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="536"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="20">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00053655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT66704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="546" mass="62354" checksum="419F556044E565EF" modified="2019-04-10" version="1">MALISSQRWNQLPRLQRVVFFMLGVAALVALIYVIASHAEPSAPSAVSHENNLIAPTPAALHPEVIENEVNVEEEAKKEGADQIIPPPGPPRKRSERQEAVVGAMKHAWKGYKTYAWGHDHLKPLSRSSNDWFRLGLTLIDALDTLWIMDLKDEFNEAREWVATQLNFNINQDVNLFESTIRILGGLLSTYHLTNDQLFLDKAVDIGDRLVAGFNSGSGVPFADVNLYSRKASNPKWGPDSSTSEVTTIQLEFRDLSRVTGNPIYEEKVNLVSDHIHKLPKTEGLVPIFINAQTGQWRAHSTITLGARGDTYYEYLLKQWIQTGRTRDFLRDDYNESVAGMEHLLARRTEPSNLLFFGELHGSKNFVNKMDELVDCYLPGTLALGVHYGMPKHHMKIAEDLMYTCTLTWLRQPTNLAPEITYYNTQPTSTNEDFFVKSNDAHYLLRPETVESLWYMYHLTGNKTFQDWGWQMFQGIENYCKVENGYTSIGNVRSTIDTKPKDKMESFFLGETLKYLYLLFMEDQSAFSVDKWVFNSEAHPLPIYTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQJ8</accession>
    <name>A0A3R7MQJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ecdysteroid-regulated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002808">
        <property type="protein sequence ID" value="ROT67454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQJ8"/>
    <dbReference type="STRING" id="6689.A0A3R7MQJ8"/>
    <dbReference type="OrthoDB" id="6576058at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032367">
        <property type="term" value="P:intracellular cholesterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00916">
        <property type="entry name" value="Npc2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.770:FF:000001">
        <property type="entry name" value="NPC intracellular cholesterol transporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033916">
        <property type="entry name" value="ML_Npc2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF36">
        <property type="entry name" value="NIEMANN-PICK TYPE C-2C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="6">
        <location>
            <begin position="54"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT67454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="19439" checksum="45C699EEDE308680" modified="2019-04-10" version="1">MCLRSQEVESQLNLRRVQQLPQHTQTHISRMTHSAGLLLALGASLIAVASTTIVQDCGSKATVNGVKVSGCELPPCLLKRGEDIVVEIDFENLQETTESLTAKVHGNIGGVDIPWFGVDENACNDLTVGDCPVEGNEKIYYSAHVPILSSYPAVAVIVKWQLLTQNNEDAACFLVPAQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N700</accession>
    <name>A0A3R7N700_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_002365</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001315">
        <property type="protein sequence ID" value="ROT78904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N700"/>
    <dbReference type="STRING" id="6689.A0A3R7N700"/>
    <dbReference type="OrthoDB" id="238316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000033">
        <property type="entry name" value="Phenylalanine--tRNA ligase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041503">
        <property type="entry name" value="AIMP2_thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040586">
        <property type="entry name" value="PheRS_DBD2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18554">
        <property type="entry name" value="PheRS_DBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18569">
        <property type="entry name" value="Thioredoxin_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="16">
        <location>
            <begin position="119"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT78904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="648" mass="72680" checksum="A7C4456804E32B6F" modified="2019-04-10" version="1">MKNKWVKKEGEKIVPVVSSINDEVQIHLQAIMSGSADNVPDKIKVDYKKRKLIKEVDLTVFEVTKGSDFTTSVSKQEAELTKDMIESGQWKSKSFKPFNFKAKGRLEQRSGHLHPLMQLRSEFRQIFLEMGFTEMPTNNFVESAFWNFDALFQPQQHPARDAHDTFYVAEPEKTLSVPEDYLQRVKKTHSTGGYGSLGYQYEWSRDEAHKNLLRTHTTAVSARMLYKLAQEGFRPVKYFSIDRVFRNETLDATHLAEFQQIEGVVADYNLSVKHLMGIIKGFFEKIGITKLRFKPAYNPYTEPSMEIFSYHEGLKKWVEIGNSGMFRPEMLRPMGVPENVSVAAWGLSLERPAMIMYGINNIRELVGSRVKMELILDNPVCTIDKFKGQSQKAANGAPTVESLTKRQELILDRLSALQSKVASIAAKMGVTLVESAASINTQLTGGVKAGVVHDVVIYADPRRPPYSLRILANALSSNFSVCLRVHCHSSVKEVSEKLQQFWGSSGATERSQSQICLTLVWRQDGDTPTALMPSLSVSPLAPNQETSFSPSPPPFSHSLPLPSSLPFPHSLPFPPFPHFLPLPPSLPLPSSLPLPPSLPLPLPLPPFPPFPDSPLGPFPLPLGRFLLRSAWLLRFPWRSSPQGTGLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NCC5</accession>
    <name>A0A3R7NCC5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000696">
        <property type="protein sequence ID" value="ROT83381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="904"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="963"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1198"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1296"/>
            <end position="1333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1352" mass="144401" checksum="0BA6B07B5A73D14E" modified="2019-04-10" version="1">MHRTKLATLPARGGERVPHGGGKTAVGAKGGQNQVEPQEPGFPSAGLCMYVYMQPPLPHPRASLYPPSYTTPRSRQLHPSAPSYTRPPPRFPLNSRLPPHNPPPPSPQIQPSPHTSPPPSVNLPLPPYPPLSRQFSPPPHPPPCFPQISQHLPSAPTATPTDHLPDKLSTHPPSRPIHQPPSTPPSLPGMILALSPTPHPTTPFPGKFSTLPSPRTTHTPTNPFQANSHPPLRPYTTPHPTLPGKVLIPPLPLSYEPHTADLTAFPGKISPPRPGNSSPSPHPPPPSCCRILTLPLQPPPQPSLAGKSSPYTSPTLHHSPSRHLVPPLPPHSPPPRPPFSKILTLPSLHPHPISPPSRQIIPSRSPNTHQPPSRKFEPPIPLHPNPTTALAGKFSTLPSLTLTPTVPLAKSSPLPPPPRANPSPFPLHPSPLPGKCLTSPLTPRPPPPPSRQYCLTLPPPYTHNPPTPSRQILTLPSPYTHTPPHPSANSSQTSLYTHTHHPFQAILTLPPPYTHTTPTSGKFSPSPSPNTTPTPFSANPPPPPPHPTPFSENSHPHPPLHPHPTNTLPGNLPPLPSPSPTPTPLAGKFSPSLPLHPHPHRPLRPKLTLPPPRQILTLSPYNALPPPRQILILPPTPTPHPPFQANPPLPLSPHSPPPTPHPTPFHGKSPPPPPTPTPHPLHKSSPPLPPSHTPPTLPGKFSPSPPPHHTPHQPLPGKFSPSPPPYTHTPPPPRQTSLPPPPPPPPPSGKILTYNHTPPTPSGKFPLPPPYTHTPPPPSRQILPPPPPTPTPHHPFPANPPLPSPTPTTPPPPSRQILTLPSPLHPHPTTPPANSHPPLPPTPTPHQPLPANLPSPPPYTHTPPPPSRQIPPSPPPPLPPFSENSPPSPPLHPHPTTPSRQILPLPPPYTTPPPLPGKFSPSPPPTHTHHPTGKFSTLPSPPTPTPHHPLPGKSPPSPPPTPTTTTPSRQILTLPSPLHPTPHHPFQAILRPSPAPTRPHPRSRHFPPSRANPAFQALPPALANPPTAPFQANSHLPSPAPTPSHARSGEISPLPPPYTHPHHPLRQILTPPSPLRPTPPHPFQANSPPSLAPTTTTHHPLPGKILTLPSLTPHPTTALREANSSPPFPLHRTPTTLPGKFSTLPPPTTHTNPYPGNSHPPPSPLHHTPPPPSRQFSPSPPPPLPLHPHPTTPSGKSSPPPLPTPTTPFPANSPLPSPYTTPHQPLPGKFSPSLPPTPTPHHPLPANSPPPLPLQPTPNHPPSRQILPSPPSPPTTHTPPPFRQILPLPSPAHYHTPPPPSRQILPPLPLHPHPPPPFPANPPPPLPLHPHPTTPSRQISPSPPPAKFYDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NDL5</accession>
    <name>A0A3R7NDL5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vascular endothelial growth factor receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000561">
        <property type="protein sequence ID" value="ROT84329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NDL5"/>
    <dbReference type="STRING" id="6689.A0A3R7NDL5"/>
    <dbReference type="OrthoDB" id="3256376at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007169">
        <property type="term" value="P:cell surface receptor protein tyrosine kinase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF600">
        <property type="entry name" value="PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="339" mass="36800" checksum="F15C0D52C92AA2CE" modified="2019-04-10" version="1">MATSSPSSASTHPSSCHQVDPQRDEIDLADLGQTPRSLPRDHPGPLSRSVSIRTGSAIAATSLATDISIGPRAVTPTTLRKQRTAHANGTAQVHNPTYRSVPTADGADEPDERERCQDSAGTVVTDLTASSSGQDYMKADSSQRARVGTRRARRASASLSIRVPLCVGRGRSLRACLTWRGGRSSTEILAARNLLLADENVVKISDFGLSRTCTGHLPEEKQCKGFCSQDLLPIKWMSVEAIRDCTFSVQSDIWAYGVTLWELFTLGSTPYPGVVVDVSFLDLIEGGYRMDKPKYATERIGTLACEHVSLGSVTQIQTWSWSYFKPQGEPPFSATLIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NPW8</accession>
    <name>A0A3R7NPW8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003414">
        <property type="protein sequence ID" value="ROT63597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NPW8"/>
    <dbReference type="STRING" id="6689.A0A3R7NPW8"/>
    <dbReference type="OrthoDB" id="360327at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="22456" checksum="31F4A8A00F6D2132" modified="2019-04-10" version="1" fragment="single">MGERKGVNKYYPPDYDPSKGGLNKFQGTHALRERARKLHMGILIIRFEMPYNIWCEGCENHIGTGVRYNAEKKKVGMYYSTPIYQFRMKCHLCDNHFEIKTDPANLDYVIVSGARRQERRWDPTENEQVVPEDKGVTRKMAADAMFRLEHGVDDKNKSKKIDLSLRQLEEFQTERWFDDYGANRALRAAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NXC2</accession>
    <name>A0A3R7NXC2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein 223</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002569">
        <property type="protein sequence ID" value="ROT69357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NXC2"/>
    <dbReference type="OrthoDB" id="5950063at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026100">
        <property type="entry name" value="Tmem223"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045325">
        <property type="entry name" value="TMEM70/TMEM186/TMEM223"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14549">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14549:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06979">
        <property type="entry name" value="TMEM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27565" checksum="DB84423CC414B642" modified="2019-04-10" version="1">MTLSRLIAGARWCQLTLSNLRGGLRNQNTLRSKEIWPTSPSATQARAHTTETRSLIEQKYAVEKDTLLFRNENRRFFKLINLFAMSQFFFWSYLSHFALTMMKDVEVPVEIRDDPNVPWWRKMNLGKYRNGITVSCFMIGWGTMALAWMYTLRSVRYLVLKKGGKTLAFVTFTPFGNKTLAVPLEKVSAKQSRMTATVHLPLKVKGKYFHYILDMRGQFPNAKLFDYSAGLRRNWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PB48</accession>
    <name>A0A3R7PB48_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003051">
        <property type="protein sequence ID" value="ROT65717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PB48"/>
    <dbReference type="OrthoDB" id="6331085at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="143" mass="15583" checksum="00538212EA63A657" modified="2019-04-10" version="1" fragment="single">LVYPEVALDLASDKVAGLVTSGEAGEDRGMLEASPEYKAKLYPCPECHKVFRHPMSLHHHRHVHKGTYTCHSCGKVFSRRWDLHRHLHRSKMGCRRPNHVTTAAAVVTTAPGTVTTTTAAAAAAAVAAHRAEFTLDLNNPPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBX0</accession>
    <name>A0A3R7PBX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002972">
        <property type="protein sequence ID" value="ROT66232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBX0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="638" mass="73178" checksum="98A0177E34F90B36" modified="2019-04-10" version="1">MMDEENMQLERGRKNRGGKTQGEREQQGGRRRGTESQKMRCSESPSPAEGASHHHPQKERVTITSRRSESHHQSASPAEGANNHHPQERKRVTITPENSASPSPEKERVTITRKERVTITRRRSDHITRRTERVTITCIRASHQSPCRRSESITRRRPSHHHLQKERVTRRRTSHITREKERVTITRRRSESPSPAEGASHHHPQRERVTITSRRSESPSPAEGASHHHGSKGASHHHPAEEASAPCTAEGASHHHPQKERVTITPEGASLITRRRKRVTITPEGASHIIRRRASHHHPQKEESPSPERSESSPSPAEERASDHHHPQKERVTITAEERVTITHEQKERVTITAEERVTITAKKRVNHHPQKEPSPPITAEEKRVTITMQKERDHHHPQKKRGHHTRRRRITITRRRSESHHPQKSVRRSSSPAEGASHHHPQKERITITRRRSESPSPAEGASHHHPQKERITITRKGANHHQPAEGAITHHPRKKSPSPAEGASHHHPQKERITITRRRRSPHHHHAEGASHHAEEASHHHPQKDHHHPQKERNYHHPQKERAEGVTITRRRSESPSPAEGANHHHPQKERITITRRRSKSPSPAEGTRHHHVDSVAYSDSFQPVLLVGVRCQILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PC38</accession>
    <name>A0A3R7PC38_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cyclin-dependent serine/threonine-protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000962">
        <property type="protein sequence ID" value="ROT81516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PC38"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1064"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1193" mass="132265" checksum="B78F5245F85402C4" modified="2019-04-10" version="1">MSYSLPQNGRSWNLPLDGRTFYLLFDGRFYLLGCMSYSLPQNGRSWNLPLNGRSFYFLLDGKSRNLPLDGRSFYLLLDGRRFYVLELEPPPLWLELVPPPREQDLKPPPRRQELLPPRRQELEPPLDGSSWNFPLDGRSFNLLDGRAFFLLDGRSFYFLLDGSSFYLLLDGRSFYLLDGMRFYLSFYLLLDGRSFYLPLDDRSFYLLLDSRSFYLLDGRSFYLPLDDRAFTSSSTAGAVTSSSTAGRLPPPRRQDLLTSSSTERRQELFTSSSTAGLLLDGRSFYLFLDGRSFYLLDGRSSFLDAGGFTASLPPPRRRSFLDGTAFTSSSTAGAFTSSRTAGAFTSSTAGARTSSTAGGFTASTAAFTSSSTAGAFTSSSTAGACTSSRRQELLPPPRQQELLLPPRWQELEPPPQRQEAEHPPRRQELEHPLDGRSLYLLPDGAFTSSTVGVLPPRNGGWNCPPRSGRSWNLLLDGRSLNLLTGDGRSWTSRRQELLPPPRREELVPPPRRQELKLSISSSTPAEKLVLLSSVGSSCIALENGQGVLPPRGRSGITVHCSIGRILLYRFLLAAELKTAELLTSSSTARELEPPPRRQSLYSPRTGKSLYLLLDGRSFYLFLDGRSLYLLDGRSLYLLLDGKELVNLLDGRSFYLSLTAGACTSSTARACTSSTARACTSSSTAGTCISSSTARACTSSSTAGTCISSSTAGAFISSLTAGACTSSTARACTSLDALVLLVAAGALSPLDGKELVPYPTVGTLLARRQEACKLSLLDGRSFISSLTAGACTSSTAEILDGKSLYLLVDGRNLYLLFDGKSLYLLLDGRNLYLLLDGRSFYLFLDSRSLYLLDGKSLYLLDGKSLYLLVDGRSFYLLDGRSLYLLPDGRNWNLLLDGRSLYILLDGRSLYFLLDGRSLYLLLDGRSFTTSRRQELLLPPRRQELLPPPRRQVLPPRWHELLPPRRNELLPPRRQELLPPPRRQVLPPRWHELLPPRRNELLPPPRRQELDPLRWKELLPPRRQELELLLDGAGTSSSTAGAGTFSTARGGTSSSTAGSFTSSSTAEDGRSFNLLLDGRSFPRRQELLPLPRRQEVLPPPRRQVLPPRRRSFYLLLDGRSFYFLLDGRSFYLLLDGRRYYLLLDGRSFYLLLDGRSLYLLLDGRNFTSLDTVGAFTSSTAGGFTSSSTAGAFTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFK8</accession>
    <name>A0A3R7PFK8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003175">
        <property type="protein sequence ID" value="ROT64873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFK8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="48709" checksum="B618AA6D631480EC" modified="2019-04-10" version="1">MRTSSPLFSLSTLLYLSLSHFSSLSLSLLSSLSFSRLLSSSPSSPLSSLSSHLFFLLISLLSFVFFSLLLFLSSFFFPSFFSFFLFFFSFFFFFRFFFFLFSSFFLFFLLPFFLFFLFFFFFFYFLPLFFHFFFLFSPVLGSSPFVFFLFFFFFLFFFFFPFFFFCILHTHFPRPPTLPRSLSRLLPPSSPPSTALLSVSPSFHLSPHPSFYPSLSPFSPSAPSPSLPSRSLISLASLGLSPSSPSSLPLFPLSFQLVVRVSRLALSLLPVPCVLAVVCVSAWHNETYGDPVPTTLLLHLSLPLTSIRPLSSVTSNLLSSSHSLSIIHSSLISSVSLVALSPLSLSSLLPLPSHLISHQLSLVEPWRLLLPSSSSHLHPGSPPHHPFSFVLPLSRILLFFSSPSSSSSTFHSISPLLSPLPALPPSLPSLPPVSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PP68</accession>
    <name>A0A3R7PP68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sphingomyelin phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_008784</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acid sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002109">
        <property type="protein sequence ID" value="ROT72812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PP68"/>
    <dbReference type="STRING" id="6689.A0A3R7PP68"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061750">
        <property type="term" value="F:acid sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006685">
        <property type="term" value="P:sphingomyelin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045473">
        <property type="entry name" value="ASM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011160">
        <property type="entry name" value="Sphingomy_PDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF29">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19272">
        <property type="entry name" value="ASMase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000948">
        <property type="entry name" value="Sphingomy_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="11">
        <location>
            <begin position="42"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin phosphodiesterase C-terminal" evidence="12">
        <location>
            <begin position="338"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="64"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="230"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="433"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000948-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000948-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT72812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="53229" checksum="DDEAEB675B653441" modified="2019-04-10" version="1">MLFVGFGCETDNPERVWEVSLPDTPKPPVQPPTLPQPDAPVMKVLHLADTHFDPFYKPGSNAECDDVYYCCREESGPPERPEAAAGQWGDYRFCDAPKWLLQALYSHIADTHQDIDFIVWTGDLIPHNLWNTSREGNLDVARQAIQMVKDSFPGIPVFPAVGNHESHPVNAFPQPYIDNEFDISWLYDEISALWATWLPGDVAASVTYSAFYSTLIKPGLRILSINTNYCYSFNWWIVYDDVDPASELEWMAQELQKAEDAGEKVYIMSHIPPGHDDCSKTWSHQYNRIVHRYESTIAGLFYGHTHKDHYMMFYDPDEPERAYHVGYVAQSQTPYHKLNPGYKIYTVDGDYQGSSYRVLDHENWILDLDEVNESNEPRMYLLYTAMEAYGLSDLTPTSWSGHLHQMSEANSTLFEDFFRYYTKDARPYRQEGCDEECKQTLLCRVAVSDTSDKSHCDHLRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSN2</accession>
    <name>A0A3R7PSN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005661</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSN2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1219" mass="134823" checksum="5B78FD8729064079" modified="2019-04-10" version="1">MEVVSLTSQSASACRKASAKLGAFPSPQDPVFRFCAFRPPHILSFVSCAFLPLMSSVSLRVPSPSGNPCLSFLSRSFPLRIPFVPPRSFPLRIRLSSLRVPSPQHPVFRSLRVPSLSILSSVPAFLPSGILSFRSCRALPQDPCLSFLREFLPPQDPRLSSLRVLPPQHPCLSVPAAVLPLSILSFRSCAFLPPGSCLSFLAFPSPQHPVLSVPSAFLPLSILSSPFLRVPPLRILSSFLRVPLLRIPVYSFCAFLFPSGPVFRPRAFLPSASLFFRFLRAFPSASCHALPARSFPQDPVFLSLPARSFPSGSCLSFCAFPSPQDPVFRSLSPQDPSSILRVPSPQRSMSFVPARSFPSGSCLSFLRVPLPQYSCLRSCAFLPLKDCSLLRSFPSGSCLSFLRAPSPQDPCLSFSRVPSPQVLSFVLPRPSRSGSCLSFLRVPSPQDTVFRSCAFLPQDSCLFVPVLPVPSGSCLSFLRVSFLRNPVFRPLRVPSLRILSFVSCAFLPLRILSFCVLPSLFLRSFPLRNPVFRSCAFFPQDPRSCSFPQHPVPRAFLPSSPQIRICLFVSFLPFRILRSFPSGSCLPRSCAFPFLPLRILSFRSWRVPFGAFLPSGSCLSFLRVPFPSGSCLSFPARSFSGSCLRSCASFPSGNPVFRFLRVPSPQDPVFRPARSSPQHPDPVFRSCAFFPSGSCHPFLRFLPLRILVFVPAAFPSPQISVFRSCAFPSPQDPVFRFLRVPSPQHLSFRSCAFLPPQHPVIRSCAFLPLRSCLSFLRCSFPSGSCLSFLRVPSPQDPVFRSCAFFPSDPVFVPARSFPQHPAFLRAFLPSALILSFRSCAFLPLRILSSSFLRVPSPQHPVLSFPARSSPQHPHPFLRVLSSASCLSFLRVPSPQDPVFRSCAFLPLRILSFVLRVPSPQERSFPLILSFVPARSFPQDPPVPARSFPSGILSFVPARSFPQDPVFRSCAFLPLRILSFVPCAFLPLSILSFVPARFLPLRILSFARSFPQDPVFVPARSPQILRVPSLLSFRSSGAFSFPSDPVFVSCAFLPLRILSFVPARFLPLDPVFRSCAFLPSGSCLSFLCVPSPQDPVFRSCAFLPLRILSFLRVPSPQILSFVPARSFPSDPVPARPSLRIPVFRSCAFLPLRIPVFSFLRVPSPQDPVFRSCAFLPLRSCLSPFLYLFPSHSLCLLLVTPPPPASQYIALPLASFSRQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PST0</accession>
    <name>A0A3R7PST0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">E3 ubiquitin-protein ligase ZNRF1</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">RING-type E3 ubiquitin transferase ZNRF1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Zinc/RING finger protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">C7M84_025282</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="23 24" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="23">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01000953">
        <property type="protein sequence ID" value="ROT81560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PST0"/>
    <dbReference type="STRING" id="6689.A0A3R7PST0"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070936">
        <property type="term" value="P:protein K48-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000235">
        <property type="entry name" value="E3 ubiquitin-protein ligase ZNRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051878">
        <property type="entry name" value="ZNRF_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46661:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0967">Endosome</keyword>
    <keyword evidence="16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="15" id="KW-0458">Lysosome</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0519">Myristate</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="22">
        <location>
            <begin position="157"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00040227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ROT81560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="21756" checksum="EDB0BCCCAB08C8BD" modified="2019-04-10" version="1">MRPAGRVAGSRVRKKGGGRHGDGVMLAGMGVLLGPACLPAPQTRTPPTPPPPSGPPFAHTSVQRLCDVSFLLLLSSSLFSSSLLSPLFSSPPYSSPLLSSFTMHPLSLPIPLPCRFKCPICSKLVLPDDLECHLVICLTKPRISYNEDVLTEDKGECVICLEDLCQGDTIARLPCLCIYHKTCIDEWFQVNRSCPEHPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTZ8</accession>
    <name>A0A3R7PTZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001577">
        <property type="protein sequence ID" value="ROT77009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTZ8"/>
    <dbReference type="STRING" id="6689.A0A3R7PTZ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018553025" evidence="2">
        <location>
            <begin position="33"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="459" mass="49595" checksum="46AD36A718BC2E7E" modified="2019-04-10" version="1">MGITKATRGLVLINQILIIVVTLPSDSRESKADTSRTSAVMPHTLKPEKRSILVFTCNPESECCLQKKRPLLRKCAFCDTPPSLSLSFHLSLSRSLSIPPSLALFPSLPLSLSFHPSLSRSFHLFLSRSLSISSSLALFPTLPLSLSFHSSLSRSLSISSSLALFPSLLLSLSFQLFLSRSLSIPPSLALFPSLPLSLSFHLFFSRSLSNSSSLALFPSLLLSLSFHLFLSRSFHSSLSRSFHLFISRSLSISSSLALFPSLPLSLSFHSSLSLFLSSSSLALFPSLPLSLSFHSSLSRSFHPSLSLSFHPSLSRSLSIPPSLALSIPPSLSFYLSLSLSFYLSFSLFLSFPLSLSILSSSLSISSSSLSISSSSLSISSSSLSVSFSLSLSKAGPALPKAATDKGASHAHGTPRKSLRPCPHQKSQAKGGIKSIAKYTHNPHHPHARLFHDMQREILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PX59</accession>
    <name>A0A3R7PX59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013679</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000271">
        <property type="protein sequence ID" value="ROT85463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PX59"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018668864" evidence="3">
        <location>
            <begin position="28"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="459" mass="46025" checksum="0649B03FCECBB81B" modified="2019-04-10" version="1">MSRPPSSRPDVLCLLLGGSSCLGGSSCWGVPPAGGSSCWEAPSCWGGSSCWGGSSCWGLLLLGAPPAGGSSAGAPPAGVLLAGGLGAPPGAGVLLLLGLLLAGGSSCWGRSSCWGVLPAGGFLLLGPSSCWGLLLLGGSLLRGAPSCWGGSSSLGAPPLLGPLSAGGSPAGGSSGGLLLLGAPPAGGSSCWGALCWGSSCWGGLLLLGALLLLGSSCWGLLLLQPLLLLSRCAPGSGARPSVAVFWIVLFRVSFLLSFVVVSKRLLCVPANESERRARLGSKEPNHVYLTLACANNLALLPLSPLPLFALPPPSSPSLTSPHFPLFAPPPPSSPSLSISLTLPCSHSLPLSPSTLFVTPPPLCSTPPSSPSLLLTFTCSHPSPPFSHSPPPLFSPSLPPPSLPSLSPPPSSPLFPPSPLSPRPLPLFSSRSSPPPSLLHLSLPLRPISPLFPSLPKFTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXS4</accession>
    <name>A0A3R7PXS4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000832</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXS4"/>
    <dbReference type="OrthoDB" id="6373272at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="10">
        <location>
            <begin position="57"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT80437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="610" mass="69952" checksum="FBD73000D9F031DA" modified="2019-04-10" version="1">MIWEFQEAFNLKEEPLGRTNLVEHKIETGDSDRVYVPPRFIPYALRPAVEAEVQALKEQGHIRVSSSEWNAPIVLVKRKDKSHPRLCVDYRALNSQTKLEFYPLPLIEDILYQVSQSKWFSTLDLRSGYHQVPLDDDSIPKSAFTTHEGHFEYTVMPFGLSNAPRTFQRLMNRVFSGQIGQGLQLFLDDIAIYTDDIDRHLQVLKEALGHRVGHGEVKAALDKLAAVKDFPTPKNRREVRRFLGLTGYYRRFIEKYAQKAQPLTKLTSEKQPFIWGSEQEEAFEVLKRSLLKEPVLRSPDFSRTWYISTDASKGAIGAILAQRYDGHFCPVSYFSRQLRGAELRYDVMEKEALAVIEALKKFKPLIWGLEVIVMSDNRSLQWLFHKAKDGNARVTRWALTAQSFGAKILYHPGKLNAAADALSRIEAPEGVDPEDIEKASTMIIDEAQNCRILMAVVANNLGGKTRQDEQEDDEEDGHPWSIDEMIREQNQDPLYSPVIKYLQTKNLLDKRKVDPNLVVEDYFLDQGLLYKQVRTPNSARDIKEVLCVPRTLVPKALALVHLAPLGGHGAEERTKFRARQNFTWRGMDRDIAEYCRKCITCAKFKGRAHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q0A1</accession>
    <name>A0A3R7Q0A1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RhoA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_016781</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003109">
        <property type="protein sequence ID" value="ROT65265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q0A1"/>
    <dbReference type="STRING" id="6689.A0A3R7Q0A1"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032154">
        <property type="term" value="C:cleavage furrow"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000915">
        <property type="term" value="P:actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001667">
        <property type="term" value="P:ameboidal-type cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022412">
        <property type="term" value="P:cellular process involved in reproduction in multicellular organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035099">
        <property type="term" value="P:hemocyte migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035006">
        <property type="term" value="P:melanization defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01870">
        <property type="entry name" value="RhoA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000095">
        <property type="entry name" value="Rho-related GTP-binding protein RhoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT65265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="335" mass="37863" checksum="53FC48C8E7B2DF4C" modified="2019-04-10" version="1">MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDAPTIKELLKMKQEPVKPEEGRNMAEKINAFAYLECSAKTKEGVREVFETATRAALAVKKKKKPNCSFFFIFSLSLSSLSSYLLFIAYYSSLSLYSSSISRFSSFSLSILLLFRHHLFSVYSSLISLLYMSIFHRSFSLTLLAIIYHFTRSSLFALYTLLILFLLLNSIAFSLLPRSPPLLVNLSYLFILSLIPLPSHQLLSPLLSLFSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q348</accession>
    <name>A0A3R7Q348_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002823">
        <property type="protein sequence ID" value="ROT67308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q348"/>
    <dbReference type="OrthoDB" id="6350385at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="18394" checksum="1109428EEE1D6BD2" modified="2019-04-10" version="1">MYVYDQKEIKSPVVRRRVYSFGFACILAALGQVAVYLFMLAVCVRQEYQDVQVASASGIMAAMTAVYAWLTGRLMFLLYERRHSEITCLEWVWWLCSIIVTVFNILLCVWFGLLSDILPTAVSAVAAALYLLFFKFAKDDIKQMGEEEEEAASREGPEYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q601</accession>
    <name>A0A3R7Q601_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Solute carrier family 43 member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002563">
        <property type="protein sequence ID" value="ROT69462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q601"/>
    <dbReference type="OrthoDB" id="6341381at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027197">
        <property type="entry name" value="SLC43A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20765:SF1">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOBASE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20765">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 43 MEMBER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="315" mass="35838" checksum="D06E7A812B27E544" modified="2019-04-10" version="1">MKRRHIKKRNKNIKGIVVRRDSSPYNGIENISENRSTFLRPFHLRTSPVAGPDQNYVVVGDKGHESQNQDTIESPSSLKTSIWSASSFLHQLWFFVNLLAINNYQQSYNVWITSSSCSVTEAGLYSMLFSYSNLLTVFFGPVGGVFTDYMIRKAYRTPNELDRRVKEVQASFWPLLVTTVFTSIMYACLLFFHPAAIYVSLLCMVVSRPCIIAVSTAYLRIRFPAGHFNRLLGIYGTVASALLFLQYPHFMWAQHMYYAAHALILAVLAVSFLNPIHLLFTPLMRHAVATRDNLKPEDLHPVRNTYADDKGVNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q7L0</accession>
    <name>A0A3R7Q7L0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_011176</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002412">
        <property type="protein sequence ID" value="ROT70569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q7L0"/>
    <dbReference type="OrthoDB" id="10469048at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="34"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="324" mass="35110" checksum="CF484775ED0F107F" modified="2019-04-10" version="1">MSWEKLLRSLVTSKSKGKCIATDAILGKDSVVVYTTNQKKRSKCKITIRGKKGVKLTMQCSRFSLASSGCDAEVLQVVDKGSKETTKFCQNDNPGDTFTVSTGNQIQLKYKKKKFRKKDGDSSLGFVYSTQADLLLGNEADCGKAFDVQVGQSAVVASTASRGTCSISLNGKSGSVLSLDCPHLQFGRKCRAEDLFVQDRIDLSLSPPVIGGICYWLVGYPLAFGEGNAFCGASYWASSGLPEDRLPTGSSTSSSPPPPPPSSPEPWRRVRSFEQKTASFESPEPDFTTFPYALLSFLFSASRNPPYVLSCFLFSASLLPFISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFB7</accession>
    <name>A0A3R7QFB7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003059">
        <property type="protein sequence ID" value="ROT65673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFB7"/>
    <dbReference type="OrthoDB" id="6376232at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="331" mass="35141" checksum="CE5BC445F1A9D375" modified="2019-04-10" version="1">MEAPNTVMPGAGPPTSGPPPGYPGPPPPYTEYPGQQQYAPPPGGAVPYGLGFCVPPPASHQQPFPPGYPAPPQPLPGGPSLYPDMSQIPQPQAVPYGFGQASAPTAPLPPTQPTLMPTRPAPSPPTQPHAPPRPQPPLATPPEYTTVGQFPQDPVLPEGHVVSPLKPLELTVFKKIGGGSPPTTADESLVGMLEVPGVWRLKLRARRCFCLHTYPDSYVFMDESTNPQDDGCPPTERVVVLQLPEDVSTTMLADLLALLREMTDLREEQEGVLHGPTKKINTAVKGTAPGAHKSTKWLRKGTGSLVRMGGSLVSKGMHLIADQVAPGHHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFU0</accession>
    <name>A0A3R7QFU0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001518">
        <property type="protein sequence ID" value="ROT77489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFU0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="620" mass="67884" checksum="C26C8247A4FEEA99" modified="2019-04-10" version="1">MPPTPTCVSAHVSPAAHSDSLRGARIPPVHTWAGNELHRPSPPLEARMHLLVHLQGWTCSDCKMSIHQRILPHEALLPLCPHPPSFSLPLPHPSFLFSPLPSSSFLSLPLPPSFLFSLSLSLLPFLFLSSFPPLIFASFSLPLLIPPFLSLPLLIPPSFSSSLSPHSSFLFSPLPIIPLLFLLSSSFFPSPPIPSSFLLPPPSFLSRLPPPPPFSSSLILHPFLSLSLLPFLSLSSILPLFLSLILLPFLSLSLILHPFSPLPPSFSLLFLPSLSLFLSPPSSFFLLLSLPHPSSFFPPLLLSLPLPPSFSLPLPHPSFLFLTSPSFLFSPSPHPPPLFFPLLILRSPFSPFSPPFSLPPPSFFSPPLSHPSPFLSSPSSFHPFLSPPSLILHPFLSLHASPFLSLSLILPLFSPLPHPCILFSSLPSSFILFSPVSPHLPSYFSRLPSFVFSTHLLKPLHSFLSLSPLTLFSRLPSFAFLSSRCLPLLSSPHMLLLSLPLPILLFFLSISFLLFSPSAPSFSRPSAPSFLFFSLSPSFSFLSLSLTLSLSLPLPQYYPLPPFPQPSPSPLPHTHTLPAVVSSGALESVARTSSIGETRVRSPSPGRWRIIREGWKETYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QG92</accession>
    <name>A0A3R7QG92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Troponin C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_015523</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002933">
        <property type="protein sequence ID" value="ROT66451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QG92"/>
    <dbReference type="STRING" id="6689.A0A3R7QG92"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="60"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT66451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="117" mass="13625" checksum="34EA83C1C644F6C3" modified="2019-04-10" version="1">MLPKTVKIVPLTEASFSLQDSLEEEQLEALRKAFNSFDRGPRIHHRRDRGHHLEDDGIKISEKNLQEVIAETDEDGSGLLEFEEFAELAAKFLMEEDEEALKKELKEAFRFYDKECK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QK24</accession>
    <name>A0A3R7QK24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011767</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002487">
        <property type="protein sequence ID" value="ROT69971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QK24"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018669148" evidence="2">
        <location>
            <begin position="23"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41006" checksum="F063BAE86FC7BC55" modified="2019-04-10" version="1">MKHYFPLSALLTLLFSASPSVPSTLSPISPLPFLPFALSLVPSLFPPLLFLPLNPHFSSSPSIPSTLSPISPLPFLPFALVPSLIPPPSLSTLLNPHFSSSPSILSTLSPNSPLLLPLLSPECSEEAASRDSFRLPRTPLSRRSLDPSGHIFSVHLAHLSSLYNFLFFPFFLSSYLLVPPILWVFVILLLLFLVFPPPPSTITSPSPVFPPPPSTITSPSPFFLICVFRTPYSPSSFPSPFLLLYSRLPPSSSSLFYFHLWFPLTFLWPGQVSHFARLSSSSDVSLRGRQTVISPRDVLTAPPAIYPSTRADDPRFVRAPVPTPRMGHALSHAHAALSPPPLPPPYTTPKSRPFPPSLPQYIPGIPNPFFFAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKC6</accession>
    <name>A0A3R7QKC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025182</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000940">
        <property type="protein sequence ID" value="ROT81656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKC6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="594" mass="64091" checksum="1B044C5A1A6272D5" modified="2019-04-10" version="1">MPSANLGARVDQELDVFSSSGPASWPVTQLTVGEDATGVESVGEDATGVESVGEDATGWRVWRRCEECEDATGVESVGVRVLAKTISSLPPWCNSWPRAALVLGGSAALSFLLSVFFLLFLALFVSLCPFVFFFLFFFSSYFFSLISLSFSLSLSSLPLPLSNPASLSPIALCPSTSLSYPTPTSPSSSLSSTPSLSPSLSTHPISSPSTHSPSLYQPIDKISTLLSLHIPLSLSLLSPASQVLKEGHFGKRSMRLQSHLFRKQTRGGRERPRESLHITTTSRSCRPTASRRHARLPATAPEGRFTCEIYCVFLPNRNLLPSPPLLFPPLPLPTTHSPLSFPCLHFPPSSSFPLSPHYPSTSFPFPHPSPLPPCPSQPCPSPPLLPRPFPSPILPSPSPPPPSHSYPSSPPSANLPLPLLLPFPFPPHPPSPALPHPPSLLSPTHHPPHFPLPPPSPLTPSPPLPTAADLIASGAHNATAQVVSDGAARRPYFFQGAIGATAAHKPRRYTQTSQKSKPVSRFRGECPRTPRHEGPCVPPAFRSRGHTMGYGGGVEGELHLKVSSSRKKQPDMSRWVSFESGFMRRAKYWGSMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLD0</accession>
    <name>A0A3R7QLD0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">15-oxoprostaglandin 13-reductase</fullName>
            <ecNumber evidence="2">1.3.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">15-oxoprostaglandin 13-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_010563</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>13,14-dihydro-15-oxo-PGF2alpha + NADP(+) = 15-oxoprostaglandin F2alpha + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133374"/>
            <dbReference type="ChEBI" id="CHEBI:133409"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:50590"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+) = 15-oxoprostaglandin E1 + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57401"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:133408"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:50586"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) = 15-oxoprostaglandin F1alpha + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50592"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:79072"/>
            <dbReference type="ChEBI" id="CHEBI:133411"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:50594"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADP-dependent oxidoreductase L4BD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01002339">
        <property type="protein sequence ID" value="ROT71135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLD0"/>
    <dbReference type="OrthoDB" id="809632at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047522">
        <property type="term" value="F:15-oxoprostaglandin 13-reductase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006693">
        <property type="term" value="P:prostaglandin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205:SF7">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="8">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="289" mass="31749" checksum="CB6C02146E4A36B6" modified="2019-04-10" version="1">MRYRARMIPVGSVMVGGQVARVIESKNPQWKVGSYLMCYTGWRSHTHIPAEELKKVGFMYSPLPDLSGMSKTLGLGVIGMPGNTAYFGFLELCNPKEGETVLVNAAAGAVGSAVVQIAKIKGCKVIASAGSEDKCAWVKELGADHVFNYKTANIDEELKKAAPGGIHCYFDNVGGDFTLHALRHMVDHARISVCGAISTYNNESKDQGKLVANSPYDTSLIITKQLRIEGFLVNRWLNRWLEGLTQLKQWVQEGKMKYKETVTQGFENMPQAFIGLFRGENIGKAVVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLL1</accession>
    <name>A0A3R7QLL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000775">
        <property type="protein sequence ID" value="ROT82791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLL1"/>
    <dbReference type="OrthoDB" id="6363884at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="794" mass="90309" checksum="332E031908124CBE" modified="2019-04-10" version="1">MSALTSVVTALVRYEVNTVVDVEKISKQLLNTTRPLVNDPRPVEYEELTSERNSYLAGVVVLCVFMAIIIILLLLCCFCPGCPLYKDRKKMKMVGDENAERVSYIRVDDRGGYRDGQPEERMWWEYLPNCCLDIAANCGFNRPPKRVSSNNGGRLAWSGDERQRYWQFGERGEGSMLEDRMMPRRGPRDLVLLEDLDEARLQQQGRMVRVDSRTSHRSQEPRRVFVLRDQRGNPRITESLREGEHYVMEDVDDTPRNMRMEDPRGMRYEDARGMRMDDPRGMRIEDQRGPLPQHGVDDDVTYARQGNAEVLRLHASPRGAVPLDDGATGRHSRPTYRRAGVEPEGIVLTQEEMQRRALMHEDAGGGPMSARLVEGQSVGVTPRSEDLLLYEGSRGYDHGSRRHHMESPPHTDVQIQTEDLANGRQEQSVPRLRIKTPIEEETNSLLEAEGIRSSRREKYQRERRRSQGNIEPQVHEDNASRKSLKVAQPANSLYHHTKASILRFESNKAKMDDEKDGKKEATTSRRNSISGTDGRRSSSVDSKGTESRRSYSHSNLDGRRSNSQAALDGRRSNSQANLEIPRGGMNDSRASVERRGSLPGLETTTGLEREAAQRSHGRRDSLGGQDRPDEAMHADGKSTHSSDYEEESGEEKDYKSTRRRQRKASQSRYMEWYDRGRDSKARDPKDSRARDSKEPRESRNRSVDRSYRDSDSKAELTEGHSRASTELRGGADSKSLSRIPRPQGASSSNLPDDLKVQEGEEELRYMMDREINLGVTYDDMQTDTLRPNSAAAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIH9</accession>
    <name>A0A3R7SIH9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">protein O-GlcNAc transferase</fullName>
            <ecNumber evidence="5">2.4.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_019695</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01003673">
        <property type="protein sequence ID" value="ROT62470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SIH9"/>
    <dbReference type="STRING" id="6689.A0A3R7SIH9"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000013">
        <property type="entry name" value="UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000019">
        <property type="entry name" value="UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11380:FF:000001">
        <property type="entry name" value="UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000012">
        <property type="entry name" value="UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037919">
        <property type="entry name" value="OGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44366:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 12" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="169"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="203"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="237"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="305"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="373"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="13">
        <location>
            <begin position="488"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT62470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1047" mass="116878" checksum="0F742ED21EFE9122" modified="2019-04-10" version="1">MSHNSQPVSSADPVKMVVKSNQASSGNVQHIATIGLAELAHREYQTGDYENAEKHCMQLWRQDPSNTAVLLLLSSIHFQCRRLDKSAHFSMLAIKNNPMLAEAYSNLGNVYKERGQLQEALENYRHAVRLKPDFIDGYINLAAALVAANDMEQAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLDEAKACYLKAIETRPDFAVAWSNLGCVFNAQGEIWLAIHHFEKAVALDPNFLDAYINLGNVLKEARIFDRAVAAYLRALNLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPNFPDAYCNLANALKEKGQVTEAEECYNTALRLCPTHADSLNNLANIKREQGYTEDATRLYLKALEVFPEFAAAHSNLASILQQQGKLNEALMHYKEAIRIQPTFADAYSNMGNTLKEMQDIQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDARMKKLVSIVGEQLERNRLPSVHPHHSMLYPLSHEYRKAIANRHANLCMEKINVLHKQPYKYPSELTSDGRIRIGYVSSDFGNHPTSHLMQSIPGLHDKSRVEIFCYALSPDDGTTFRSKITREAEHFIDLSQIPCNGKAADRINQDGIHILVNMNGYTKGARNEIFALRPAPVQVMWLGYPGTSGAPFMDYLITDRITSPMKLATQYSEKLAFMPDTFFVGDHKHMFPHLKERVLIESVLLNNEGIKDTVALINTTDLSPVIESAEVMTIKEVVNPATTKESVEVAVTVAQLPSTAPIESMIQAGQVQATVNGLLVQNGLATTQMNNKAATGEEPPQNILVTTRKQYGLPEDAVIYCNFNQLYKIDPSTLQMWCNILKRVPKSVVWLLRFPAHGEANILAQAQQLGVGAGRIIFSNVAAKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMITLSGETLASRVAASQLHCLGCPELVAQTRQEYEDIACKLGNDREYLKATRAKVWKARIDSPLFDCKTYATNLERLFGRMWKKYSGGEKPDHITEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SKN6</accession>
    <name>A0A3R7SKN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003170">
        <property type="protein sequence ID" value="ROT64903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SKN6"/>
    <dbReference type="STRING" id="6689.A0A3R7SKN6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="554"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="585"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="624"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="716"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="769"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="801"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="841"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="862" mass="94261" checksum="12BC6A7070724398" modified="2019-04-10" version="1">MEDSRPDGERPGGGDDAGCLEQTQRRRDHSTGLAPACLCLGVQEGARGPLRDAVSHEQGTVRQTPTRCFLGLQKQEVQSLQTARDIRGRGTYSRLTTSRGKTGIRWAAQKRVRAARSCWVSLLGAVESRRAASSSSVLRRRRDFALATRLFGDLGVALSSFAFSSPSFFLLPSFLSSSSSFSLSSSFLSSSFFSFSSLFLSSLLLPSLLLFFFLSLPSSPSLPSSSPSLPSSPSLPSSLLSSSSPSSPSSFFLLSSFFSLLFLPLLLFFFSFSLPSSFLSSSSFSSFFSFSSLLVPSFFLLLLLFLFLPLLSFFLSSLPTSPSSSFFLSFSSFLSFSSSPSPSSFLSFSSSSFSSLLLLPSSFSSFFFSFSSFFLSFSSFFLSFSSLLPLLLSFFSPSPSSLFPFLPFLLSLLSFSPSSPSSFFSPSSFFFLLSFSFSFLPFPLLLFLLLLFFFLPLLSSSSLSPSSLLSSLSSPSSPSSSSSPLPSLPSLPLLSFFPPLLLLLLPSSLSFLLSSFFFSFSSSFLSFSSFFLSFSSFLSFSSFFLSFFPPLFSSFLSFLTLLLFLLFSPFPSFFSPSFFSPSFSFSLLSLLSFFLSFSSFFPLSSLPSSSPSLPSSPSLPFPSSFFSSFFLSFSPSFSFSFLLLSFFLLLLLFFLSFPSLPSSPSLPSSPSLPSSSPSLPSSPSFSFLPSFLLSSLPSSPSLPSSPSLPSSLFSSFFSFFPSSLLLFSSLLLFLLPSLLLPLLLFLLPLLLFLLSSLLLLPSFLSSLPLLLFLLLLLFLLPSSFLLLFLSSFFSFSFSSFFFLFFSSFFSFLSFFSFSFLSFFFLLLFFASLSSPSPEISFFFSSVCLCAWVFGGGVECFCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SM61</accession>
    <name>A0A3R7SM61_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative rho GTPase-activating protein 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015264</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002901">
        <property type="protein sequence ID" value="ROT66714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SM61"/>
    <dbReference type="OrthoDB" id="9994905at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23175">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23175:SF23">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="58"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="898"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="970"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1048" mass="113470" checksum="6B186EFC54880A44" modified="2019-04-10" version="1">MDEWMTPTTLRSPTPSPSLLVSIPTRTPNSPLLPDELLADHGGPAASSLSSLEPLDTIFVKNVKPGSAAHLAGLRTGDRVVSVNGESVATQSYQQVVSTIQRSPPVLQLMVVPREEDLLQQVFGETAHNPESNLDVRMPTPSPGHIPPQQSSRQHIPPTNFSHSPLGIPQYPQNLSPSAWSSQSSLTSHISNMSTGPHPPPVMVVHPPFHQRPHQASVIPPPHGAHIPIHPHHQQTTTRQNQANVQYRAGPRKHSLASAGDAKKSTVGSVNRKQSLPMVVDRKQAVYTIQNTISGVPHHVPSPPGNQSSLPTSTNATGTAPQVATSEHASASVFGVYEPILDRAVGRGSFRDSRRLERDPDGRIYEVVQTRVVESKFNTGDSDKKESGRQNKGHHSNQGTHVGRKASVGDADVKRVRVQSLSPPRLKVDQIHARSASVNTRPEALNNNGVNEGSIHGSHQSLNSTKSEGKNTNRQNSHSRKSYSEPISSNKENYMTDDKTTQEVIERIKKDTERKEEFLRRPNQPIWLPASKSPVIHSDYHVNPQKFQRPIWPPPGAQTPPSPGAITKALTFIVAPKQDHSHLRRVKSEIEQRQNSIDNSSSMRGSSVPAGSNLSESSIAGQEMDGTPEDEHSKQNLPVAQGASGALPRSLVVNAVPKPYVGSASEANPANLRFGKSFTTTLSRIQENIPIPEYGSSSSLTSQGQTSSKQGDTSQGVTPGGTPSGSQTSLNSASLRSIPLAWVGDNERIKQLQIVSRRAKQFESSQLEKEASAKSAFHRFELSRLSQRSKIPNVAQRKQEFETKDQLPPGFDFEFGTHFNNTPRQRKSAELMKGDLVCHEMSPSPPKVFRSLSDGGNVFPVNRRLYSPTAEEGVKTATVSEAGVVRRVAINRTIPVGGPHIHCEPPPLYGSSHRPQSDPDVLERERSNSVCSQVSMTSLLSTQSMDETGSSRQKTVARQNSYLSALRSPLHVASSQAHTPGAGGGTGVPGGAMEAITRCEGTPHAGRRELPDLLGVLGSAVFPPLTLDLHYRPPGPTCDLPRDGMDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SNU3</accession>
    <name>A0A3R7SNU3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit E</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_013013</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002629">
        <property type="protein sequence ID" value="ROT68829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SNU3"/>
    <dbReference type="STRING" id="6689.A0A3R7SNU3"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT68829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24636" checksum="51B6E4424CA139D2" modified="2019-04-10" version="1" fragment="single">IHHMMAFIEQEANEKAEEIDARAEEEFTIEKGRLVQQNRLKIIEFYERKEKQVELQKKIGASNLLNKSRLEVLKAQESHINNVLHEAQQNLNQLTLNQGAYAKLLEDLICQGLCQLLEPSLILRCRRADQSLVEHSMAKALATYRSLTGRDCKLQIDTANWLPAEICGGVELLTKGNRIKVSNTLEARLEMLAQQMLLGPIELCCFGPNPNRKFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SP27</accession>
    <name>A0A3R7SP27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002611">
        <property type="protein sequence ID" value="ROT69046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SP27"/>
    <dbReference type="STRING" id="6689.A0A3R7SP27"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="887"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1149" mass="115883" checksum="73893FB67EB2C390" modified="2019-04-10" version="1">MSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDLLWIRLQLAPAPLRKQPPLQATPAPPLPQIPPPLWNQVPLQRYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTDSSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTQDSTHSSSQTSSTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTESSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTILLLIQAPHPIQPPPPPKPPLQLLHLAPAPDQVPLQRRTQPLLQAFPHHPWIPALLQLPPLRTLLTQAHKPLQTYTSSSLEPTTSTFPSSSSDSTTSSFQSTTSPTESSVDSTTASSSTTEETTTSSSYSSSTSSTDTTSSMESSTSSTSDTTTSSTFSTSSLDSTTSPTTTTDHSTDSSSQTSSTYTSSSSGYSSSSSSSEPTTSSTYPSSSSDSTTSSSEATTSTASSSSSTSEETTMSSISSSTDTSSSIGSSTSSTSDTTTSSSLSTSSLDSSTSPTTTTEDSTDSSSQTSSTYTSSFQATSSSSPLLNHTSLLSKLLIRFNHVLLRSHHFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SPM7</accession>
    <name>A0A3R7SPM7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative zinc finger protein 1-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_012061</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002525">
        <property type="protein sequence ID" value="ROT69718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SPM7"/>
    <dbReference type="STRING" id="6689.A0A3R7SPM7"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001227">
        <property type="term" value="F:DNA-binding transcription repressor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000688">
        <property type="entry name" value="zinc finger protein 197 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399:SF70">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24399">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="335"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="196"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="630"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="686"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="196"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="643"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="658"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="699"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT69718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="715" mass="79175" checksum="E2604BFA1231BFD7" modified="2019-04-10" version="1" fragment="single">DDDEVLMSKHVCLSCFNIAVDVQAFIDSSINFQKTTIRQIFPEHKLVETQDITLIQAPFGSLRKESEIVEHHINDDGKVDEPVLKSQDLLQNGCFLETSNVLLKSKFATTDKEEDIAEGNIASDFQESPDSVNADVSHSNVKVTINSSELGVIDQVSKDEIPSVHNEHVPELPSISTEFQTDPSVKTDVKITDEGDKVSNCSKEDACDTAHSPLASQRQSTNSTNSSTNKSKKAKVVVDRQEKGKESSKTCPVCSKSFPRQSQLKSHLVSHSGTRPFECKICHTKFKYRRNLVEHSSIHNEIPSFICSKCGLTFKQRSNLLKHERIHREKDKHCYRCPHCNNQYTQSSHLRTHIRNVHENNKGHKCDVCDAVVLCQSSLRRHMATVHANSAKFVCPHCNKGFNNNQNYQGHLRRHSGERPYSCSTCTKTFTTTKALSRHRLIHQGIKSHKCIHCSKAFYELCDLKKHAKRHLKRVKKSNKSLAPSKAGENASNSTTQVVTGMNSLNLMVLTESLLFSEPQPLLETSAPRVTEILLPDGKLGTPKEVTAQPLLGPEVIEANPPNLQQSSMELSKISNMLQPGEEVLTPSPLLPATPVLSAENVEAISVLADTAVLQPPETKTVIATPIDPSRVLQPTDMGVEEELPRPENRDVSLEAQEASQCSSSTDGPTMVVLSSVGASSEYLPVAEQESHTGNSEIDGARHQQGERILSHATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SPN9</accession>
    <name>A0A3R7SPN9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UNC-89, isoform e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012011</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002521">
        <property type="protein sequence ID" value="ROT69764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SPN9"/>
    <dbReference type="STRING" id="6689.A0A3R7SPN9"/>
    <dbReference type="OrthoDB" id="6085115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010909">
        <property type="entry name" value="PLAC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50900">
        <property type="entry name" value="PLAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018681379" evidence="4">
        <location>
            <begin position="17"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="PLAC" evidence="6">
        <location>
            <begin position="51"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="98"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="317"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="49192" checksum="DB69000D7AE1BCC0" modified="2019-04-10" version="1">MLVVALILTATLVAAGEEVDVLDPSSPVGELTVSQFEKLMARTLPRALIPLHHTCTDYSETGDCGLVVENGLCGAEEFYARYCCRSCTLAKQIPTFGPHLSLEAKVPVEARITTEERELRYGENVTLTCEVSGEPAPDVLWFVSDSSHDVSEERKATVEDTGGILKKTRRGTITLPVTQSDSYFGCDCLAISAAGWDRSSFQVYFERDIGLSMQLLPGERLFSLSDNITLECTAEGASLDEIDWKMEGEILESSDNYSIIKERSVKDGETRIHSSLTLLRPRVMDTYIKCFATSLTGAVKDATTRVRVKVTADSHIPSDAEAPLRINLGTPPYEDIRYGGQARFICESNGYPGTQKVVWYKGNTTIEESDHFSIEEKVWKYPMGCHVTSYLIIKSINKRDFGKYTCKAANSVTESEASVMFQIDRYGKFGFDFLTQFMNESST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STA0</accession>
    <name>A0A3R7STA0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007454</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001946">
        <property type="protein sequence ID" value="ROT74060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STA0"/>
    <dbReference type="STRING" id="6689.A0A3R7STA0"/>
    <dbReference type="OrthoDB" id="549353at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08824">
        <property type="entry name" value="LOTUS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="59"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="200"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="487" mass="53863" checksum="1C4DC47C099385ED" modified="2019-04-10" version="1">MQFNRFIPAYHHHFGRQCRVAAYGFSKLIELFEAIPDVLQVYDDEEDGEKQLQLVERERVRVLGDQVGAVVRGAPRQAIRISALTQVFTRYYGYSLKPSHYGGNTLEELIGKLRNHVKLVETGDEPVVALVDRGYVHEIMVRARKLLWEDSSCSYPLDKFVQTYTDRYGHPPSIEVIRRDLEDVLVIEGEGEEAKVNLVPLQMFARDLLTLLHEAGGRMLLLNFDTAYLDRFGVACRPATYGFPNIVALVQALGDLVAVRGRGTKRILVLNRDSAPSPPSFHIPTSSSSFYGDNTEGASANSDAKPPPPSHLPPPNKVTPPQQCDYQRYIQEANSNSHLMMGMNAPTPHPSYQPSSPVVYPGSPAPTGGSVMWGQMWSPQYPVMPPLSPAHYMAGKLNEEYAAPPSASELPPPELFTQMHPQEQMAAQVTAPDNCNQTSSSVICEEADDTWSSCNSDADKGEGNTTSTPVAPKLRTKRRLAAQFAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAA2</accession>
    <name>A0A423SAA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_021090</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004318">
        <property type="protein sequence ID" value="ROT61162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAA2"/>
    <dbReference type="OrthoDB" id="6380356at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT61162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="777" mass="87290" checksum="44A1A5417C37C27A" modified="2019-05-08" version="1">MARECNSTCALEEYLKLQERLSYYVFVSRQYSGEAPGEAPGETLEAWGPRDRQDPFASGVWQVAKLGDDGQPLNGLTIDSLLVKVRPINCRRPRLKGPGFSFGKCFSKRMQEKHRCIPVYLDSNVTIADACKVSVLHHAIVDTDDEEDLCNVQTMRGCSYTQWTHEVKSGLSMVKLNSYHLELAFASPKIRVETEIDLYPFSQLASDIGGSLGLCLGMSLLTVWRWILVPSDKRPYSTSHHFRHLLYWSVVTLLTFSTALHGLVSLQEYFSQPPLIAVTPAGSTKAAGRTDRDILSDQVAARLASRALDCRQDHLSEGEECVLDCLMKSALQQVGHVAPFIDVKDLPPCQERDYWEPRSTYVVPSLPMATVMDQLLVRSCRRRCSHLGALNASDMETPKGMAINHEYYRITACDLLCCLGGIVSLYAGLFLSSLIPAIVSFLPDTTRKARLFRRFLTMALESTIYVSGAALSVLLVYRYIFAHPISSSSSGQPLRTAEQPVLTACHFPPFAEPLREDSALPIDAQWANAAWPERISRVAITQEVGRMAAGEHDSNVTSVVTPLNRCYTVTAALPYNNFVAAFYYWWDDNDSVVFSIHNHNDPPFVSKVFHLKSYSAVTLTVTPFHYTRLGQDDHPEQSYDLCLYRCVHDGYSDAVGCRLPYVDWRPDLPLCDPATARRHPAWPRQPLERPPAEDTDSPCHKACRRRLREFYLTTTQTQPWIEPGINIIQKRGNYHDFREEDWYELSQLGNDLGVVAGFTLGTSILSLLQAAVQSFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBS7</accession>
    <name>A0A423SBS7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004046">
        <property type="protein sequence ID" value="ROT61654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBS7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="50784" checksum="439B18845B3F39ED" modified="2019-05-08" version="1">MSFAFFFPCLFLFFSSFLSLSFFFSLSFCSVPFLLPCLLSLLSSFFFFLFLLSSSPFLSYILLFSSFLPFPVPLPFGFSAFFPLVLFSLCFCFFFSFFLPFLSFYFPLFLFLFSPFLFLISFLSAFCSLPFFFFFSSLSLSLLLFFLFPSLFSLPFLPPSLLFLLPSFSSFSVSLSFSFSFFSSSSSFLFSVPFPPFFFPSLSLSSLLFSPPSPLFSFLLFSFSILLPSFSPSFFFYFFFPISFLLFLPPLLACFPFSPFFLLAPFPFLPFSSFLILSFLLFLFPLSSFPLFLFSSSPLPFFFRPLLFSVSFCSLLPFSFFFPCSPPLLFLFFFFSCLLPSFFSFLFSAVVSSSLPSLLSCLFPLPLYFLLLSSSSASPSLPLFPLSSSPSSPLFLLSFFFFLSPFFLYLSSLSLISFFPLVLPSFLFPLFPFLLLFLSFPLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBU2</accession>
    <name>A0A423SBU2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sorting nexin-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBU2"/>
    <dbReference type="STRING" id="6689.A0A423SBU2"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000004">
        <property type="entry name" value="Sorting nexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019497">
        <property type="entry name" value="Sorting_nexin_WASP-bd-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827:SF1">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10456">
        <property type="entry name" value="BAR_3_WASP_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="PX" evidence="7">
        <location>
            <begin position="82"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="48752" checksum="B5F9552B0BE9599B" modified="2019-05-08" version="1">MSYDNDDWDDDWDDDDSETGTSNLNGAGNFGLSAPNRSVKPTSSVGDVSSAGAGKASVDEKEKVFVDETANGPRWRPNPHEFTCAISSPKKESKFHGMKSFIAYTVMPSFSSTSVSRRYKHFDWIQARLSEKFPLIPIPPLPEKQISGRFEEDLIEYRMTMLQSWIDRICRHPVVAQCEVFHHFVTCPNDEKLWKTGKRKAENDKLVGANFYLAIERSDQPLDMIQTEAKLEGYTRFFSNMDEAVKLLQNTCLDQAKKHQTAYKREYNKVSHAFSKLSRAFDTDPSNCAPGLTEAIHHVSEAYADIGTVFEEEPKHDWDPLCNLLFEYKGLIDGFPSVISVTKGAIAKRRQVEKEASEGRLDYDQVPPMIKRSDTVAYALHAEVAHFHDERTRDFKKAMTSFLTEQINFYQKVTDRLREALQKFNDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDF5</accession>
    <name>A0A423SDF5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003761">
        <property type="protein sequence ID" value="ROT62215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDF5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="49096" checksum="58F08B2FDE83DF07" modified="2019-05-08" version="1">MPPTLPLPPLVPPPKNIPSPSPLGFEISRPSPPPLGFEHPPRPPPWVRHIPSPLPPLGSKHPSPPLPPPLGFEPSHPPFSPPVRTSLPLPSPWVRHITPPLPPLGSNIPPFAPSPRPPPLGSNIHPLRFEHPLPLPPWVRTSPPSPVPLSPPAPLPPPSWVRHIPVRTSPPPPPLGFEHPPLPLPAPPWVEHPPFPPPSPPLGSTPSPPPSLPLPPWVSNTPPSPSPPWVRTFPLPPLPPPLGFDHPPPPWVRNTGSGTSPFGFEHPSPFLPTPLVRTFPPPSGSKPRTAARGLRVAVDGRESESRLQSGSTAIERRGGDGGEGGGGGGEEDLSKGGSEGRGGGGKRTCHLLRRNTTPTPAPLLEGDVLPLPPPPLGDILSEQGKKMEKVRNDREMSTKAPRASQRKAREKGGGGAGIDGTRDRADNGAHQSAPSPLKARPIGCFVSECSLFRTVHFVLGGRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SH18</accession>
    <name>A0A423SH18_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_018606</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003430">
        <property type="protein sequence ID" value="ROT63506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SH18"/>
    <dbReference type="STRING" id="6689.A0A423SH18"/>
    <dbReference type="OrthoDB" id="21182at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000241">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050778">
        <property type="entry name" value="Cueball_EGF_LRP_Nidogen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513:SF13">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46513">
        <property type="entry name" value="VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00058">
        <property type="entry name" value="Ldl_recept_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 6" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="repeat" description="LDL-receptor class B" evidence="7">
        <location>
            <begin position="84"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="221"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="269"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT63506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="306" mass="34396" checksum="7C075A4F52C4CDD8" modified="2019-05-08" version="1">MAVPTNHDQDNSRTRREAAKITVVLRDLKKPRSVAVDWVTPMVYVVDAGDKTILATTVDGSKVVTLIATSLDQPYDVVVDPQSGQLFWSDSGFNPRIEVAGMDGRNKRALVDRNLQWPVGLAIDYPARRLYWADIKTCNIETVMLDGSDRQLVMHFPQNEGVPGNLDIFEDMIYLTTHDTNVVHRLNKFGNRPQHMSCISQHAMEVSDILIVQEQKQDRSLFNPCANNTCHANALCFISGPRNYSCICRDGMMEKIVDGVQQCLPKSASRNGCNLFCNRGKCIMTPKGPQCQCPDMYYGPTCNMYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHF1</accession>
    <name>A0A423SHF1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pancreatic lipase-related protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018506</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003414">
        <property type="protein sequence ID" value="ROT63604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHF1"/>
    <dbReference type="STRING" id="6689.A0A423SHF1"/>
    <dbReference type="OrthoDB" id="199913at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013818">
        <property type="entry name" value="Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000734">
        <property type="entry name" value="TAG_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11610:SF173">
        <property type="entry name" value="LIPASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00151">
        <property type="entry name" value="Lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Lipase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="218" mass="24441" checksum="E1B406C3A301BF6A" modified="2019-05-08" version="1">MQYELLNTSDCNVISVDWPAGSGWWLPSYYTAVSRVPYVGKDTAWLLRELVAYKGLNLKDVHLIGHSLGAHVSGLASKHFKTRVGRISGLDPAGLTFHNVSKQQRLDKSDADYVDVIHTNGCYTFWRPWTDCYGINENLGHSDFWPNGGEHQPACKGVSGDIGCDHELAYTYYLESISYGIDDTYFLARNCSAWNQYEEGECPCGDEAQYMGFFVNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKN2</accession>
    <name>A0A423SKN2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acyl-CoA dehydrogenase/oxidase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003188">
        <property type="protein sequence ID" value="ROT64795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKN2"/>
    <dbReference type="STRING" id="6689.A0A423SKN2"/>
    <dbReference type="OrthoDB" id="10262177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046359">
        <property type="term" value="P:butyrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00567">
        <property type="entry name" value="ACAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="2">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="145" mass="16537" checksum="8171AA5DED9D6DDE" modified="2019-05-08" version="1">MCINETIQYTKNRIAFGQPLLNNQYIHFRLAELETELESLRSLLYRAVDLYAAGHNVTKLASMCKLKSGRLAREVTDSCLQFWGGMGFTNEVLVSQLYRDLRLYSIGGGADEIMLTVISIYMGILPQQSKMNWRKSVTCQGRDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKZ4</accession>
    <name>A0A423SKZ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative G-protein coupled receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_017168</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003172">
        <property type="protein sequence ID" value="ROT64886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKZ4"/>
    <dbReference type="OrthoDB" id="6347073at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000034">
        <property type="entry name" value="Low-density lipoprotein receptor-related protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051360">
        <property type="entry name" value="Neuronal_Pentraxin_Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277:SF161">
        <property type="entry name" value="LAMININ G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277">
        <property type="entry name" value="PENTRAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="746"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="12">
        <location>
            <begin position="258"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="476"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="771" mass="87024" checksum="782940EDDB4A9D60" modified="2019-05-08" version="1">MFLFPLRYDFAVLIAAPTPARSERVLLLQADGLMTNESWAQSSVVAPPTPSASVCIRFKVFFFRPLTHVFSLTSKEESREINGGLLNVNKEGPCFDPGQKVFVDYVRPIVSSAFYFLGISEPLQVLTWYHYCLTYDHTNATIAAYLDGNLQGTISRNTTRRFAEATLVLGQYSIEYLKGYTQARSFSGHLTHAGVWNRPLSPQEVAELAACGSVRRGLVIPWDQEWILSNASFIEVATEDICEKKTKASYLKLSAMPYAAALHACSGLGGRLPVPRDLAHALELIQQLREPEAIAQTWVGATDEGVEGTYVDFYSGKPMTWFRWGSNDPNGLQWQNCLILDEDFLHDYPCHVSRETLCFLPTQLEWTLRGPCEEDTANYKFSLLHPAKGQVVFRGYYQYEIAEEGDAWVWRNALTDEVLGRLPHEAERWPMGRKNWTIEGEVCERSGVQQVLQLSSCTPGQFTCRDGSCIPRPLRCDRRPDCHDESDERECRLVQPPLGYHHSLPPPGSAPGVPLPVGLSMKIVSLSLSDKDSYLETTYHLNMTWSDLRLRFHNLKGASRLNQVPTTEHDTLWSPTLTMVNVRGTERTMVDSEAVLTIHREGEPLEDDFTVPEDIYAYLGSENHLSVERKYTSQFLCDLDLALYPFDVQRCFMALEVLSAATDFVVLEEAISTVSYVGAKLLIEYELLSAASGIGSSIRVAPAEGKEARDVPLKALPKPTRGLSRWVLGGDIESHLERNRKLCDKLYKYAMIFIPCYFLFFNVVYWLYIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLP6</accession>
    <name>A0A423SLP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003133">
        <property type="protein sequence ID" value="ROT65156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLP6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019584241" evidence="2">
        <location>
            <begin position="24"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="71732" checksum="448D4DE737A48CFA" modified="2019-05-08" version="1">MSSSLYSQSSLLLLLLPHTPILLLLIPPFPFLPLPSISLPPSLHSHTTLPSLPPTPSPLFFLLLSPSPPTMPLSHPLSPLPQPPYSLPHLLPLAPFISSPLTPSHPHPPPQSYTPIPPSIPSSKPTSLLSSSPPLLSLLLLSTPPLTLITSPSPLPSSLPPKPFSSLSPPLLLLPIPLLHLLLQPSLLPPQLPLPSLSSPHIPFFLPTPFLPHTSSLPPLKSLPLPPPLSLPPTRSSSCPPTHSPLPPPQQSHFTSQPSLLPPHTPHTPSTPTFSSPPHPSPHTHPSTTPLPQPTTLPVSHPPHRPFPSLPSHIDVSSLSPPPPLPPIDVPTPPLLPPPSPIRRHLPIPTPPPSLPIDPAPHPPSSIHRRSTTLPSPIHKTPPAPLPLSIPIDPPPLPSPPSLPIDTSPSLLNPIRPPLPLPSQSFHRPPLSSPPFPFPSYRHLPLVPPPRLSLPYARPPRTPPLPQSHRPSPSPPTPPSSPSSHRPPLHPPPPSTPTDRPSRPPPPITLPSLLPLFLKCPSDHPPSHPPPSAPHHRDPLSLHSDSTLHPPSHQTSLSTPSLPHIPQITLPPPSRPSLASSSHRPPHLPSLPFPLIYPLPFPSPPPSIHTDPPSPPPLNPIDLPYHLALPPFPFPTDLYPPTPSIRRPPPSLPPPSLKSHKPPPPPPSLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPY0</accession>
    <name>A0A423SPY0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002965">
        <property type="protein sequence ID" value="ROT66267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPY0"/>
    <dbReference type="OrthoDB" id="6361562at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF5">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUB" evidence="3">
        <location>
            <begin position="144"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="41234" checksum="B31D3E7042A9182C" modified="2019-05-08" version="1">MTGACAWRLEGGSLPGGWRTIRSLDPDLEALVVLRYPGTPHSASTLRCWFDKHSDTGSRMLSRVLLVVALAAAAHAAAVAEESDRDSKLFPVINIITFDNAPCTAQSGEMGTCYSQKECEGLSGTPSGTCANGFGICCVLTATCDGTISVNGTYFTSPGYPSTYSTPGTCMVELLPPAGTCQILLEFESFNLMGPVNGDCNNDTFIVMGANAGSRIPVICGANTGQHMYIDVDQSNGPYKMMVTSSALAYPRSWKIKVTFLDENDPCKAPPRCLQYFKETSGAITSFNFGPEPMMLTNQEYCICFGYNPGFCDIGMNFNRLDLGNINGNCGNDYLAVGAEKLCGDFGTLTAQANATGPISLCVFSDDNNDREEEGFNVNYLMLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRD4</accession>
    <name>A0A423SRD4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002891">
        <property type="protein sequence ID" value="ROT66756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRD4"/>
    <dbReference type="OrthoDB" id="6428908at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="563" mass="61502" checksum="808003403E9EFAEF" modified="2019-05-08" version="1">MREGDRQRPNASAAFPHFHPFGSPSCERRVCPAASRLAMILQRTPCHALSRLTCTECDGDATPDGVMNKARHVLTDPRTRKHGSSCCRTATPGFYPSPFRAPQGALSIMASLQVVITRDYVTAYGIRRKHKPAPVQPLLVPAAGGCPGTSGFNGARSWHYCDLDGRQASFLCPNGTVSTRRSSCATGYNFDCESAPYLYSLNERVFALPEVDETAPHRTLTAEMLETIFLRSGRGRENLCDSSPLFPRCSDPRAPPPGLFSPLPHHPSSHGPSPPPPRLPLVLLRLFRFLFCLPRISFLHFHVPTSQVSSSPPTLLPPSFPLLRKPILLPTLQDFSSRISSTIPLLVLSKLSPTYPSSLSPCLSFSPFPFYSTTPLLPSFRLFLSHFLATLPSSPFFPPFPSRFSALPLLLPILRCPPSPIFLPVPLLPLPPLPHLLPLPLPIPLPHLSLPSPPPHLPTPSPPHPLSPSPFPSPPSFPLPSPSQSIPPPHPPLPSPSQFIPPPQPPLPSPSPPPLPSPPQPPLPPLPFEVVNARSFPTTSGEHQDKGAKIRPYLLEVFFFCKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSB5</accession>
    <name>A0A423SSB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014866</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002853">
        <property type="protein sequence ID" value="ROT67071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSB5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019550544" evidence="2">
        <location>
            <begin position="19"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="585"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="675"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="702"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="769" mass="84254" checksum="E403364D58FA8C43" modified="2019-05-08" version="1">MLFLLLFFLLLLFPSVDALPLLLLAAASVCRCSSSSSSCCCFRLSMLLFFFFFCCCYALLLCCFRLSMLLLFFFFCCCFRLSMLLLLFFFLLLPSVDAPPLLLAAASVCRCSSFSSSCCRLSMLLLFFLLLLPSVDALRLSMLLLFFLLLLPSVDAPPSLLPAVSVCRCSSLLLAAASVCRCSSSFFFFLLLPSVDAPPLLLAAASVCRCSSCCFRLSMLLPLLLAAASVCRCSPSLLCCRLSMLLLFFLAAASVCRCSSFSSSCCFRLSMLLLLFSSCCFRLSMLLLFFFAAASVCRCSSSSSCCCFRLSMLLFFFFLLLFPSVDAPLLLLLLFRLSMLLLFFFFLLLPSVDAPLLLLLLLPSVDAPPPLLFAAASVCRCSSSSSSCCCFRLSMLLFFFFFLLPSVDAPPLLLLLLMSAAASVCRSSSLLLLLLPSVDAPLLLLLAAASVCRCSSSSSSCCCFRLSMLLLFFFCCFRLSMLLLFFFCCFSVCRCSSSSSSCCWSVDAPLFFSAAVSVCRCSPLLLLAALPSVDAAAVCRCSSSSSSCCCFRLSMLLFFFFLLLLPSVDAPSLLPAAVSVCRCSFFFFCCCFRLSMLLLFFFLLLLLCRCSSSSDAPPLFCLSASSSSSCCCFVSMLLFCCFRLSMLLFFFLLLLCSVDASSSSFLLLPSVDAGFLSMLLFFFFFLFLILLLLAALRLSMLLFFFLLLPSVDAPLFLAAASVCRCSSSSFSAASVCRCSSFSFLLSCCFSCCRCSSSSCFFFFCFFFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423ST21</accession>
    <name>A0A423ST21_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">RING-box protein 2</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
            <ecNumber evidence="16">2.3.2.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">RING finger protein 7</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">Sensitive to apoptosis gene protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_014581</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>S-[NEDD8-protein]-yl-[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-L-lysine = [E2 NEDD8-conjugating enzyme]-L-cysteine + N(6)-[NEDD8-protein]-yl-[cullin]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="26">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Catalytic component of multiple cullin-5-RING E3 ubiquitin-protein ligase complexes (ECS complexes, also named CRL5 complexes) composed of CUL5, Elongin BC (ELOB and ELOC), RNF7/RBX2 and a variable SOCS box domain-containing protein as substrate-specific recognition component. Also interacts (with lower preference) with CUL1, CUL2, CUL3, CUL4A and CUL4B; additional evidence is however required to confirm this result in vivo. Interacts with UBE2F. Interacts with CSNK2B, the interaction is not affected by phosphorylation by CK2. May also interact with DCUN1D1, DCUN1D2, DCUN1D3, DCUN1D4 and DCUN1D5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RING-box family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EC" id="2.3.2.32" evidence="16"/>
    <dbReference type="EMBL" id="QCYY01002820">
        <property type="protein sequence ID" value="ROT67346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423ST21"/>
    <dbReference type="STRING" id="6689.A0A423ST21"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031466">
        <property type="term" value="C:Cul5-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061663">
        <property type="term" value="F:NEDD8 ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16466">
        <property type="entry name" value="RING-H2_RBX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000156">
        <property type="entry name" value="RING-box protein 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 21" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="23">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="22">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="22">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00044971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00062884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00069656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00078874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00083543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT67346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="12638" checksum="A79C91EDC49A0349" modified="2019-05-08" version="1">MSNDVEIQEGEAENNTSDSQKPEKMFTLKKWNAVAMWSWDVECDTCAICRVQVMDACLRCQGENKQDDCVVIWGECNHSFHNCCMSLWVKQNNRCPLCQQEWSVQRVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423ST79</accession>
    <name>A0A423ST79_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002815">
        <property type="protein sequence ID" value="ROT67391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423ST79"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="43634" checksum="FF9E19959B15C2D5" modified="2019-05-08" version="1">MCRSFFAQPPLFVTPFSQSLLSLPCFLSMSSLSATPPPLNYSVALFPLPYPSVCHSISPLLSSLLYPLPVLSLPSPPSSFTPLCLSLKITPFSPSPVTPFALLPLHSLVLLPLCHFPLPLLSHSFGHSPLSSPSLTSFPPSLHSFAPPLTRPPLPLLSSLLHSLLSLLVTPSPPSLTLRPLLCHSLSPPLSVSLSSLTPFAPPPFSLLLLPLSVTTSPPPLSLLPSSSLLVLLSLCHSLSPPSHVPLLSSLPLSVLPSPLPLSLPSLSHSCLPPLSVTPFSPSSRLPLSLPSSALLCHSLVLLPLSVTPFSLLSPLTPRPPPPRPPSPPPCHSLVHPPPLSDLYSVFPHSLAFANRVTPKLLSPSPPPLCAPLALEPPDEAAASARESSRLRHQDLIRFILFPLLRRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423ST92</accession>
    <name>A0A423ST92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002810">
        <property type="protein sequence ID" value="ROT67428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423ST92"/>
    <dbReference type="OrthoDB" id="6371812at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="180" mass="20138" checksum="94E4CD0199FBC0A5" modified="2019-05-08" version="1">MASPVSFLVLLGAKLPDIVVVSSVLVILQLELPTKRLPLHWRVKGTTMRHAQDIAGRALQETRQEEREQMRFRHRRKKRFVELKGVSAEMLTLCIGGVRQRMRGSCPSWPLPDQEGLPGGRRNTWASVNAPPPPTQNTNTPAALQVTDRRLSGGTATADQLDAQARTKQTWRGRTHQVPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STB9</accession>
    <name>A0A423STB9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002809">
        <property type="protein sequence ID" value="ROT67437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STB9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="596" mass="64242" checksum="7D4DF5D1117DA00A" modified="2019-05-08" version="1">MAPPEGKQPKGTDGLPWQPPKVVSQTKGTEGFKFPFFTRVSAPWHLRTAANSKPQRRRTTPSLPIGEARAEDRAPFGNLPIGNFKIARGDRLLALAPPEEQSQQARRAGPPSAHHADPPPLSQILPNGNLKGPDWRGSIAGTSTPERQRQEGTDSKGLGAPLAPSSRRQLKGVLSRSGRVCTPLFGRVAYLSEWKSLKADRLWAPPWLLLPYRHHIKGNSKYGGVSGGSLAIPSQLKGNGSAWTSLCRQPPKGNCKEDGGLLGTSKANLKRDNPWHNKHQIKATNTKEREGGAPWHPPNRQLQRDGRASLGTSGRARTSTNSATEQGFTWHLRRAKITPRRRGSILVTSRRQAQADLKAKKKSWHGRLLLLTPSKGHQTHNEGTGSNLLRAHLPQVNSKTVEGNLKGAGASLGHILPKGNSNAAGLSGSTLALSKCATTKGTVRAKGSLWAPPKGKLKWDGGSSLGTSEIDNSKGTLPSRSYSSNLLHLGTQPPKRQLKRDGSCSLPGKAPPKAILNQRVTGAPWHSPHQASNSPKAERWALWHPAKGKLKVPHGWALGAPWQLRMAKLKGGTGSQLRHTREGNIHKGGRGSLAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXA9</accession>
    <name>A0A423SXA9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002639">
        <property type="protein sequence ID" value="ROT68728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXA9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="494" mass="55769" checksum="1D25D87152D23DF4" modified="2019-05-08" version="1">MLLRLAQEQAQGSLTRRPRGEAKRQRHQKKQPSPETSNSQDMKSSKSLPLLLFLLLLLPLLFHFLLSIFLFLLPSPPFPFLSSPSLSPSLSSSFSISFSFFSSPISFSLSSFFFFFSSIPLFLFIFSPISSSLIFFFPSLLFPSLSLSFPFSSSLFTCPCFFLRPFSLPLSILFFAFDLLPRFSNPSPSRFFLFLLAFVPLLNIVLPLFFDIPPSFFLSLFLLSQSLSLPPFLFLLAQSLSLPLLLFLLALPPLSVAFPPSSPFPPRPYLSPSPVPPPLRPLLQSHVAASPSVFLKARLVYPRRSICYRYLSFPFYSLRMAGSILRYSLKLRLNHFTAIVTRFSIKKQRKQLQRRFNLKGFKREGAARIRDTRKLTWLVPRPGASVARNKGKVAAACATSSPNSIQRSFPAYKRPIAFNPHSRVPPPHPRAWLMHAPPLHLRSRRSSRREGEGGSSTCATMTCELVGARAREKGAPAFSRACSRYRALAHPPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY13</accession>
    <name>A0A423SY13_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012899</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002618">
        <property type="protein sequence ID" value="ROT68948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY13"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="603" mass="68162" checksum="4724EC992A501EF8" modified="2019-05-08" version="1">MVHAQTNDSDTASSCSSKTPPPPPRAQKTSRPFSLPKALERYAAFSSFLPQPSRARGGNAAFESQRRKPQPSRARGGNRSLREPEEETAAFESQRRNRSLREPEEETAAFESQRRKPQPSRARGGNRSLREPEEETAASRERGNRSLREPERAALTEPEEKPQPFESQRRKPQPSEARGGKPQPSRARGGNRSLREPEEETAAFESQRRKPQPSLREPEEENRSLREPEEETAALPQPSRARGGNRSLREPEEENRSLREPEGGNRSLREPEEEKPSRARGGNRSLREPEEETAAFESQRGNRQPSQPSRARGGKARSLREPEEEPQPSRAREETAAFESQRRKRSLREPEEENRSLREPEEETAAFESQRRKPQPSSQRRKPQPSRARGGKTSPAFQPFREPEEETASPQPSRAETAARERRKPQPSRAKEETAAFESQRRKPQPSAAFRSLQPQPSRAREETAAFESQRRKPQPSRARGGNRSLREPEEETAALTAAFSLREPEEETAAFESQRRKPQPSRASKSQRRKPQPSRARGGKPQPSEEETAAFESQESLASRARGGKPQPSRARGGNRSLREPEEETAASLVTTFLSVFLSLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0P8</accession>
    <name>A0A423T0P8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011666</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002471">
        <property type="protein sequence ID" value="ROT70072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0P8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="77127" checksum="E11DE96718DD9B29" modified="2019-05-08" version="1" fragment="single">HHTRISTGHHTRISTGQHLYSRISTGHHTRSRSSHLLQVTTLASLQVRVIASLQVTTLSTGHHTLSTGHTLASLQVTTLAVTTLASLQVTHSHLYRSPHSHLYRSPHSHLYSPQLASLQVTTLASLQVTTLASLQVTTLASLQVISRSASYRSPHSHLYRSPHSHLYRSPHSHLYRSPHSHLLQHHTRISTGHQHLYSHRISTGHTHLYHHTRIYSPASLQVTTLASLQVTTLASLQVTTLASLQVTTLASLQVTTLASLQVTTLASLQVILYSHHNSHLYRSPHSHLYRSPHSHLYRSPHSHLYRSPHSLQRHHTRISTGHHTRISTGHHTRISTGHHTRISTGHHTRISTGHTLASLQVTTLASLQVTTLASLQVTTLAISTGHHTSTGHHTRISTGHHTSHLYRSPHSHLYRSPHSHLYRSPHSHLYRSPHSHLYRSRISSPHSHLYRSPHSHLYRSPHSHLYRSPHSHLYRSPHSLQVTTLSLQSLASLQPHSHLYRSPHSHHSHHIASLQVTTLGHHTLTPHLFTTLRSPHSHLYTGSQVIPLPSHPPTITPTCLLRPSSDLHAVPSPHHLHHTPALHSPPPTFITPLPLHSPPPTITTPLLLHSPPTHLPHTPPPPLSPTTFITPSPSTLFITPLTLPPPTPSFGFLVHFWPGSLRVYITLAINVFSIGLLRLKSVLVIAFIYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2T4</accession>
    <name>A0A423T2T4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_010902</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002382">
        <property type="protein sequence ID" value="ROT70800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2T4"/>
    <dbReference type="OrthoDB" id="6378450at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019326042" description="EGF-like domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="39991" checksum="BA414A3A71D5739F" modified="2019-05-08" version="1">MASGKWSRTINLLCLSLLTLLIHACGGNVVVLENEGGTGREPCVVGENGEMVNCDDTIEVRYDLLWNSNIATYEFNDDLASVPCSNDSVCRACLPDLDVALMQNSPLPTAPFCDVDRNATEPGRCTCGEGRCVSYSRDMSTSSVYYYCGPCGWVGARCVESNCTHEQAKCSNGYCECVQGGLFYDLSVCYYPSFGKTMIIEMLVSSLIVVAMCGVLAFSYNRLSRSRQRDDGSSTFPWRRGSGSRESPTSDTPPTYDDVVDKLPSYQDALKMSPKADDNGGITNFAFEMELSPAPPPPYEESQKRKTEEKTTVTENGRKVQLAKEIPEGASPTQTNPSERHEVLGQPIEQALQNAMHDLQRGSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3F1</accession>
    <name>A0A423T3F1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002351">
        <property type="protein sequence ID" value="ROT71026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3F1"/>
    <dbReference type="STRING" id="6689.A0A423T3F1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="463" mass="52044" checksum="666FBA1DB503D161" modified="2019-05-08" version="1" fragment="single">SLSFYLIYPSNLSIFLLLSSISTFFLSNLPYFLSISPSFYLPAPLSSISALFYLVSRHSFYAIPLLFYLFPFFPSISPSFYLSLHASFYLSPPLSIYPRPLLSISPSFYLPPPISIYLPLFLLSPALCYLIFPLFYLSAPFFSILPFFLSISPSSYLLPFFLCYSLLLSNLSPLLSISPLCYLSPPSSMLSPPLSIYLHPFYLCSPLSIYLPPLVYLSPLFSIYLPPLSIYLRASFSPPLSILSPFFLSISLLSILSPALLSIYLLPSFSYLSPLFAIYLLLCSIYLPRSLSIYLLPLFYLSPPLLSISPFLSISLVSIYRPPSSIYSTSSFLSISSSFCLPLSLLFYAPLFYLSCPFFQSSPLLSIYRPPLSIISPLSIYLPVLSIYLPPLCYSISSPLMLIYLPSFLSFPLFLIYPPPLSVYLPSFYLSPPLSIYLPPSLLSIFPFFLSTVNRLLSIPASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5D5</accession>
    <name>A0A423T5D5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009922</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002256">
        <property type="protein sequence ID" value="ROT71736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5D5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="61768" checksum="9CD9F5D97C05F3BA" modified="2019-05-08" version="1">MGYYFSPSKDGGGGAEAEVVGGEIGPRTSADRCVHFPAPFPRSSLWLSCPLPLRESSSPPRLFPPLPTPPPPLLLSSFLPPLPTPPPLHLSTTTTPPLPLLPPLLPPPPPPPHTTSFSASASTPPHLYSTSILPSPAGLTLVRVRFASPFPETHMCTFRPFIPRRGAPWSRLKAPSKVFSIPRRPAPFSSHSFLFFLLFFFLLFFLSSLNSSSTLLINHLPLLFLLTPLLPPPPPPLHTPLLSSCHHHSSFLSSFTPSSPLPFLPPPSYPCITCTPVLKHLSPRCVSPPLPHAHCAHSGPSSPARRSLHSSSSCALFFPFLFFLPFSLFLFFSAPSCFFLLFFFSSFFPFPSPFSISLFLLFVYVHLLPPLPHQLLLLLLTPFLLHHTTSPPPPLLLLLLLYSSPSPPPPPLPLPPPPSSPLLLLLLPHSPPSYPCITCQAKPNAKTQAKSPFAARLKFLSSVHLAYSLTLSWPPPPPPLRLSPLSLSLPLLLSPPLLLLSLPPLLSPRFPLFFLLLLVTSSSSSSTFSSFSTSSSFSFSTSSSSSSLSTPPSLLLLHPPRHLDPFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5K0</accession>
    <name>A0A423T5K0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Projectin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002255">
        <property type="protein sequence ID" value="ROT71757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5K0"/>
    <dbReference type="SMR" id="A0A423T5K0"/>
    <dbReference type="STRING" id="6689.A0A423T5K0"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000321">
        <property type="entry name" value="Bent, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000097">
        <property type="entry name" value="Bent, isoform F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000460">
        <property type="entry name" value="Bent, isoform J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000107">
        <property type="entry name" value="Myosin, light chain kinase a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000553">
        <property type="entry name" value="Uncharacterized protein, isoform J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633">
        <property type="entry name" value="IMMUNOGLOBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47633:SF7">
        <property type="entry name" value="TITIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="254"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="379"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="582"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="5">
        <location>
            <begin position="690"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="476"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="511"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="527"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT71757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="782" mass="88011" checksum="30BBAEDF77D69A7B" modified="2019-05-08" version="1">MVLIFEFLSGGELFERITAEGYVMSEAEVINYMRQICEGVKHMHEKNIIHLDVKPENIMCQTRTSTNVKLIDFGLATKLDPNEVVKISTGTAEFAAPEIVEREPVGFYTDMWAVGVLAYVLLSGLSPFAGENDIETLKNVKACDWDFDEEAFANVSNEAKDFIRRLLVKNKEKRLTAHECLMHAWLRGDYSPRLEPIDMMRYIPIRDKIRAKYKEWEKFLLPIGRLAEYSSLRKLQLEKYRIHDTHFDRRQCAPRFVIRPQNAFAYEGQSVKFSCRIVGVAVPTVCWFHNNMELRQSVKYMKRYSGEDYTFVINRVKLDDRGEYIIRAENHYGAREEPVFLNVQPMPPEIPQYRPQEQIVRRRQALSYKMWQEESEGAPSFTFLLRPRVIQCHQTCKLLCCLSGKPTPTVKWFKGNKELTKSDYTMSHADGVVTIEIVNCKPGDSGKYKCVATNHLGTDETSCVVIVEDRRYIETTIKDLPPPPTPAIRVEDSSSSSSYFSSTHKSAATIAVTSSSSSRQESRSSKVETSSTSVSASSTSTGAKRQLKPYGKRQDSTGSTSRSRSATKELELPPDDALMGPPGFSGELPKALAVKDGDPLCLKCTVKGDPEPQITWFKNGEPLSSSDIIDLKYKQGLAALTINEVFPEDEGEYVCKATSSLGSAETKCKLKVTPMEQQVNGKGGPGDKIPRITEHLKSQEVPDGTPITLNCKIGGATKFDVVWLHNEKEIKPSKDFQYVKEGDNYLLKIAEVFPEDAGTYTCEAFNDVGETFSTCTLVILSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5T4</accession>
    <name>A0A423T5T4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002246">
        <property type="protein sequence ID" value="ROT71793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5T4"/>
    <dbReference type="STRING" id="6689.A0A423T5T4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="491"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="585" mass="63218" checksum="1C2F7E5CED8FA738" modified="2019-05-08" version="1">MQPLPSLPQIAAASDAESDTWVRPPHLPPSNPSPTPLGLGPPGPPPFSSPNIYPNFPPFPLPHRTIRSHFPSFSSHTLHFHNPFPQPIHPTHPSPTHSHPHNRPHLAQNPFLPLHWSFPPTPHLLLFPQHPLAPLPTSFPSLNPFNPHFPNPFTVTSQSFSSPPPIHIQHLFSSFLLYPSIVTLTPSLPPTSPPPIPLLPHTLPTHSPPTRLLPSHPSIYLQHPFSPPLPHPSTSNTPSSPPTHTSTSNTFSPHPPPSTPQHPSPLSIHLNTLSVPPLNLSTSNTSSPSSIHHLQNPFPPHPPNHLPTPVPSHPPHTSTSNTPSPPCPPIHLQYSSPLPYPSISNTLSPPPLPPPFQPFLPSPPPTHTSTSNTPSPLTHNIYLQHPFSPIHPPPTPLLPLPQPIHSNTSSPSLNPSTSKTPFPPPHPNHPNTRSPPPPHTSTSNTPSPLPPPIHLQYLFSPPYPSSPTPFSPSLPTFQPFPPSPPHPHPTSTPFSPSLPTHTSPPTPFPPSYPPHTSTSNLSPTYPSHPHTPSPHTSTSNALLPSPTHPFTPPPPPEETANNGSLSRANEAVLTGRFRSDTRDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAA7</accession>
    <name>A0A423TAA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002031">
        <property type="protein sequence ID" value="ROT73368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAA7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="425" mass="45474" checksum="1ABF3E50A1021FC9" modified="2019-05-08" version="1">MGREDLPTPFSSLPLYPPIFPIPPTALFTHFCLSLLSSPSPSFISLLPPLPLLTLLSLPYPPPLPLPYPPFTLLTSPPLLTLLSPPDLPLLSHSSSPSLTLLSLSLTFLSSPYLPLPFLTLTSLPIPSSPSPYLHSLSLPPLPLLTLLSLSLPSSPSPYPHLPPHTLTSLSLPSSPSPYPPLPLFPSLPDLPLPLPTLPLLSLPSSPSPYPPSLSLFLSLSLPSYPSSPFLTLLPSSPSPTLLSLSLPSSPSSPSPYPHLPLHTLLSLLPSFFLLSLSLPSPYPPHLPPTLLSLFPPLHTLPLLTLPISLSLPSSPSYYPPLHTLPLLTLISSPYPHLPLLPSHLPHLPLLTLLISLSLPTPLPLNAHPSPKQRADERALIGLFPHAAAVATCGGSGERMRRARTQRDILLTGELRRAVSPRAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH98</accession>
    <name>A0A423TH98_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001716">
        <property type="protein sequence ID" value="ROT75890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TH98"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="820"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1052"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1239"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1312"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="842"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1409" mass="161748" checksum="3EB8A5BD1F65367C" modified="2019-05-08" version="1">MTPEMETANSPARRGGGKFTCKTWRRQIHLQDVEEANSPARFEEANSPAKTWRRTWRRQIHLQDVEGGKFHLQRRGGGKLQTWRRQIHLQDVEEANSPARRGGGKSARRGGRHNLQDVRRQITLQDVEEANSPARRGGGNSLQDVEEENSPARRGGGKFTCKTWRRQIHLQDVEEAKSPARRGRRQSQPARRGGGARRGRKFMQDVEEAKSLQDVEEAKSPARRGGQITCKTWRRQIHLQDVEEANSPARRGRQIHLQDVEEAKSPARRGGGKVTCTNSPARRGEANSPARRGGGKFTCKTWRITCKTWRRQSHTARRGGGKVHLQDVEEANSPARRGGGKFTAGEANSPARRGEGKIHLQRRGGGKVTCKDVEEGKFTCKTWRRQFTCKTWRRQITHLQDVEEANSPARRGGGQITLQDVEEANPPADVESKFTARRGGGKVTCKTWRRQIHPSKTWRRQIHLQDVEEANSPSTTWRRKFKTWRRQMQDRRQNSPANVEEAIHLQDVEEANSPARRGEANSPARLEEGKFTCKTWRRQNSPADVEEAKSTCKTWRKAKSPARRVEERQIHLQDVGRQIQPARRGGGKFTCKTWRKAKKSLKTLRRQITCKTNYLQDTWRMANSPARRGGRQIHLQERGGRQITCKTWRRQNSPARRWRRQIHLQDVEEANPPARRGGGKVHLQRREEQIHLQDVEEANSPARTWRRQIHLQDVEEAKSPARRGGGKFTCKTWRRQIHLARREEAKTCKTRGGGKFTCKTWEEANSHCKTWRRQWRRQSHCKEANHLQDVEEANSVQDVEEANHLQDVEEANSPARTLEECINSPARRGGAKSPARRGEANFTVTWRRQSQPARRGGGKSHLQDVEEANSPARRGGGKFTCKTWRRQSHLQDVERQIQRRGEANSPAPADVEEAKSPARRGGGKVTCKTWRRQSSPARREGGKFTCKTWRRQIHLQDVERQNSRARRGEEANSPARTWRRQIHLQDVEEANSPARRGGGKSPARRGGGKFTCKSASHARRGGGKFTCKTWRRQNSLHCKTVEEAIHLQDVEEANSPARRGGRQNSPARTWSGGKVTCKDVEEANSPARTWRRQIHLQDVEEANSPARRGGGKFTFKTWRRQIHCKTWRRQIHLQEGRQKSPARRGEANSPARRGGGKVTCKREEANFTCKTWRRQIHLQDVERQIHLQDVEEGIHLQRRGGGKFTCKTWRRQIHLQRRGGGKSPARRGGGKFTCKTWRRQSSPARRGKEANSPARRGGGKFTCKTWRRQNSPAKTWRRQIHLQDVEEASKFRKTWRGKFTCKTWRRQIHAARREGGNSTCQSVEGQIPPARREEAKSPGKTWRRQIHRKTWRRQSHLQDVEEANSPAARRGGGKFTARRGGGKMSPARRGERPNYTCKTWRKANSPARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TID7</accession>
    <name>A0A423TID7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">[Acyl-carrier-protein] malonyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_005210</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the type II malonyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001684">
        <property type="protein sequence ID" value="ROT76213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TID7"/>
    <dbReference type="STRING" id="6689.A0A423TID7"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.250:FF:000005">
        <property type="entry name" value="Malonyl-CoA-acyl carrier protein transacylase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052760">
        <property type="entry name" value="Mitochondrial_malonyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170">
        <property type="entry name" value="MALONYL-COA ACP TRANSACYLASE, ACP-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170:SF2">
        <property type="entry name" value="MALONYL-COA:ACP TRANSACYLASE (MAT) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="14">
        <location>
            <begin position="95"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="15"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00061523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00077751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="44087" checksum="1C86AA8D258C9854" modified="2019-05-08" version="1">MSFLRPISSSSYCLARGASRKPFDGGTVTVTEDTYGRESPKELLDNATTYSEQEPHTHEDLWTEGPYPHKSNFKQSQAKNSRRPKVDPRETSVLLFPGQGTQYVGMGKELLKYPNVNEMYEVASQILGYDLLEICLSGPSKQLSKTIYQQPAIVVSSLAAVEKLREENPALLGGFSVGEITALTFAGVFSFEDAIRLVKVRAEAMQLASEIVPSGMMTVFYGPDSRLGFACSVAKEFCQRQGLTEADCRIASYLYPHCKVVAGNEEALSFIEENKADFRLKRLKRLPVSGAFHTDLMLPAVSALKKVLNTITVENPLIPVHSNIDGKYYKDAEQVKKQLPRQICKPVKWEQTMHILYERNRGTAFPLTFECGPGKSLKAILKMCNAKAFDSCSAIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMH4</accession>
    <name>A0A423TMH4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative slit-like 3 protein isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001501">
        <property type="protein sequence ID" value="ROT77635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMH4"/>
    <dbReference type="STRING" id="6689.A0A423TMH4"/>
    <dbReference type="OrthoDB" id="2013775at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF210">
        <property type="entry name" value="CHAOPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019465691" evidence="4">
        <location>
            <begin position="24"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="14120" checksum="8C4A0727E675371D" modified="2019-05-08" version="1">MSVRRLQLMRAFLLACLAGAAAATCPCAWDPSASSLACGDLGLTEVPTACFDAHPGARTLNLTSNEITQLRRKDFSGNVDNLEVLLIDNNPVSMFYPDAFAELANLQEVSIQTTVFAAISSRPFQEQPKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU10</accession>
    <name>A0A423TU10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU10"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="627"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="717" mass="81728" checksum="201AB87F04574242" modified="2019-05-08" version="1">MPLATRRHRTWHHEEDGHAPTRRNRHWHHEEDRHPGPQEDRHWSTLRGGSPWRPRGDDAQATRGGSHLHQRRIRTWSHEEGSHWHYEEESPPGPRGGSPQAHEEIALAPERMPTWHTRRMQPAPEEGSPLAPREEIRHCPPRGGIAPGTPEEDRHLAPRDRHQAPHEEIAQDNTRGSPLDPTRRIANGTHRGESPRTTRRIANLEPTSKEVPPGTHEEDRQSCNPTRGSPPGTYEGVIALADRGGGSSLATTRKDRLDRTIATGTIRRDRQHGTTRRNSTPGDYEEDRHLAPRRKDALAPTRRIATGTTRSNRTGTLEEDRHRCEPRGGIPTGTSRRSAMAPTDGGCSLHLEEDRHMAATRRNGHWHHEEDRHMARVGRIATWHSTRDATGTTRRIRTWNHRGGSPRAPTRRIATWHHEGIATSNHEGGSHLAHGRIACTHEEDRTWHHTRRMPPGTNEEGSHWHHEEDRHWHPREDAHLAPRGGSRTWHPRGGSPTGNHEEDRPGSPNEEDRTAPTREVSHCNLTRRIANWQPEEACHWHTREDRPGNPKEIATWHRTRRMHRARRGGSHCTRGGSALDHEEDRHLAPTRRIATRHPRGDRLATSRKASHRAPTMRVSHLAPTRMDRHLAPRGDRQGTTKEGATRHPMSRIAIQAPRRRIAPGTHEEIRHQAPHEEDRQLAPTRRIATLATHRGDTPTRHTRGGSAHLGHPRRIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUV7</accession>
    <name>A0A423TUV7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="22">RIO kinase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Serine/threonine-protein kinase rio1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">C7M84_001036</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="28 29" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. The catalytic activity regulates its dynamic association with the 40S subunit. In addition to its role in ribosomal biogenesis acts as an adapter protein by recruiting NCL/nucleolin the to PRMT5 complex for its symmetrical methylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 25">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="20">Associates with the precursor of the 40S ribosome subunit. Interacts (via its N-terminus) with PRMT5 (via its N-terminus). Interacts with WDR77. Found in a PRMT5 complex composed of PRMT5, WDR77 and RIOK1. Interacts (via its C-terminus) with NCL; this interaction targets NCL for PRTM5 methylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001139">
        <property type="protein sequence ID" value="ROT80236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUV7"/>
    <dbReference type="SMR" id="A0A423TUV7"/>
    <dbReference type="STRING" id="6689.A0A423TUV7"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000232">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 24" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 28" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 24" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="27">
        <location>
            <begin position="93"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="26">
        <location>
            <begin position="411"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="26">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="26">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="23">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="23">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00057025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00063876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00068838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00076008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="ROT80236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="54046" checksum="6D34E015F194E99F" modified="2019-05-08" version="1">MPMKIVKAHVYHVGSYQQLQYQSQFAMKIGMKIVVIQSQKVEKFQPSEKLFKKYVGKICLEKFEGLRGFEGNVTNRMVETQRKAESERQRVRDKAERATVEQVLDPRTRMILFKFLNKGTIAEINGCISTGKEANVYHALSSDGQNYAVKIYKTSILVFKDRDRYVSGDHRFRTGYGKHNPRKMVRTWAEKETSNLFRLYNCGLPVPKPIVLRSHVLVMEFLGTDSMPSPRLKDADISESKARELYHDLVVQMWIMYRECRLVHADLSEYNLLYHNGRPYIIDVSQSVTPDHPHSLEFLRKDCTNITEYFRRKGVPTMKIQELFNFIVDPMLTAEKRDEYLEEMKEIAASRPVGELTDQEKIDEEVFKNAYIPKTLDQVIDFERDMQQLKLGTKSEKEITYRTVLGMKKDLSGPEVLPIPGDASDSGGDSSEAIEQLEDSGERPQKTGKKGRRQSRKHKQRKENRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW06</accession>
    <name>A0A423TW06_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL24</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000623</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001096">
        <property type="protein sequence ID" value="ROT80636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW06"/>
    <dbReference type="STRING" id="6689.A0A423TW06"/>
    <dbReference type="OrthoDB" id="1727108at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000002">
        <property type="entry name" value="60S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="94"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="163" mass="18294" checksum="A89E825083543BE5" modified="2019-05-08" version="1">MKIQLCSFSGYKIQPGRGKTMVRTDGRVMVFLNARSEAAYLMKKNPREVRWTVLYRRLHKKGVEEEVTKRRTRRTQKFQRAIVGASLTDIMAKRNMKPEVRKAQREQAIRAAKEKAKAAKAAKAAAKKPAPPQGAKQGKTGAKVPKVQKGGRPAQGGRGQRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TX11</accession>
    <name>A0A423TX11_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TAR DNA-binding protein 43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_000297</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001043">
        <property type="protein sequence ID" value="ROT80976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TX11"/>
    <dbReference type="STRING" id="6689.A0A423TX11"/>
    <dbReference type="OrthoDB" id="2020831at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19609">
        <property type="entry name" value="NTD_TDP-43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12321">
        <property type="entry name" value="RRM1_TDP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12322">
        <property type="entry name" value="RRM2_TDP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000098">
        <property type="entry name" value="TAR DNA-binding protein 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000107">
        <property type="entry name" value="TAR DNA-binding protein 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041105">
        <property type="entry name" value="TDP-43_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033">
        <property type="entry name" value="RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033:SF9">
        <property type="entry name" value="TAR DNA-BINDING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18694">
        <property type="entry name" value="TDP-43_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 17" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RRM" evidence="16">
        <location>
            <begin position="108"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="16">
        <location>
            <begin position="194"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="258"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="364"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="274"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT80976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="46919" checksum="B9B98400C876EBA9" modified="2019-05-08" version="1">MVKMSCYIQVCEEENDEPIEIPTEEDSTLLLSTLVAQFPGACGLKYRHPDSRGLRGVRLVDGRLHAPDEGWNYVFVCVFPKENKRKSDDHLESSMSKTKRMESKQRCSDLIVLGLPWKTTEKELREYFEPFGEVLMAQVKKDPKTGQSKGFGFIRFGNYDTQQRVLSQRHMIDGRLCDVKIPNSKEGMVQQVNSKVFIGRCTEDIGPEDLREYFSKFGEVTDVFIPKPFRAFAFVTFLDPEVAQSLCGEDHIVKGTSVHVSNAAPKSDPNRGPFGRGGRMGDGRGYGQGGYGQGMNNGGVWNQGGNREMPNLAALGTSLGLGGPGQGGQGGGQNVNPLNMGALTMPMLAALSQASWGLLGNLQQQSQDGTQAPGGYNQGGQSSQGHSNPPPSNQSQGGWGSGSSGGGWGDGSQSGSWGPSQGRGDKGYNRGDYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-09-13" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXP7</accession>
    <name>A0A423TXP7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycine-rich cell wall structural protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001001">
        <property type="protein sequence ID" value="ROT81227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXP7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019539336" description="Glycine-rich cell wall structural protein 1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="23232" checksum="C9108609D776B04F" modified="2019-05-08" version="1">MKTALIAVLAATLAVASWAAPEASGGYGSGGGGGGSFGGGGGHGIGGGAGGSFGGGGAGGYGSGGRGGGLGSGGGTATINFNLGAPKGSSGGGFGGGHGGGSSGGFGGGFGGGWAVEARWTRRRFSGGLAEASEVVPQADTVVVPVEASEVDTEAVPVGGFGGGSSGGYSGGSSGGFGGGSSGGFGGGHGGGSSGGFGGGFGGGSSEHACVHELCFFREIRDEQGRPAALIQLWNLETRWNGGGATSFLPKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYR1</accession>
    <name>A0A423TYR1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000956">
        <property type="protein sequence ID" value="ROT81552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYR1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="562"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="805" mass="86961" checksum="3FF8A08BF70BAFB9" modified="2019-05-08" version="1">MFFTVRSTTLITRELFAEGKLGGGDEGGRGPWGPPGRPFPGANLEQTYGRRIKVIAGEGEEEIATEKIMRFWMKCAASERRVLASYYLPRSPVDLPAPAPSAPFLPAPPPLSSRPSPPLPTPGITPALEKSAGGRRKEDTQGGYHCSWLRLEGVEGVCGPSPPHRARHPRCTCPSPEALRQARKALAARRVRASRDPRCTCPSPSGSRDASPWSGTSSSPPSTPATASPPPRHPRCTCPDPDISRRLSVARRARSARDLRCTCPSTPTPPPSREPECTTAISTDHGDFVRLSDSPAKITEPDVLFRKARGKGKRGKGRGKPRHVKSEGEEPSSEGGGEIGCAAQRERGEEAHSSQPSSPARRVKDKLCHLRHKMVSGVAALAAAGKAHHAANKENEGRVCTCGDTPERQRRMAPGVVTRVLPPPTPPPPPTPSRAARAREERAGYEKAGKDASFPVEDIPQPLLEDVCSPLGNVPPLSPPGQPIIRENLLHHPITRHLLNLGSTFTLASASSSPTKEEAVGAEWKVPVGDNLRHLHKLSASHGHLDLSDGASLSRTRSLELYAKDQSQGKESKKAQPSLGGSAVYLPGSPKAEAQRSMKKIPYQAASRKMQFGDSGLYLSTPCISSGGVTSASRSTLKVSDCSTVDIPSMSACNNPDYENVAFHNSGGYVMLSKRLLDQWQLSYEACIPPEGAFIDIDNGGMMTTENGGRATLDDVTPSHVGGLVEPAEQPDVEREIVQIARRQSEELRQAIIESPRRQSEDLRDTLRRQQQEKKVETLRRQKKEDTWALQSVLADTAKIARTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZX7</accession>
    <name>A0A423TZX7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000898">
        <property type="protein sequence ID" value="ROT81988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZX7"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="565" mass="62070" checksum="257730A7B86925E3" modified="2019-05-08" version="1">MEPLEKAFAVVEEVVGKICRSLGPEAQNHINHDRLFTKAERQIKNGLSIEVASKTIVSALMPDIQATLKEKVKDQESYDVQENDLPGANEENIEPTVFSPELRASTSRSPVYSDIQNGSSARESSQSSSTTLDSPQSAESQSSSTAMTLNDFSEISVLTPEPPKPAPVIDILDDSFSSRPSSRNSDILIVEEVEKPMKPSARTEEGTCDDTKKNEDISKILSMLHDLEKTLGLAKAKENRRAYVLGLYIELAVDQGEMVPDRVFHGLRAAKKRPHGDTVGSGSNAVVKRLKVEEGDAKCVSEIKQWQQPVGETNQLLSDSLPSTSGAVVPKVAADSTFKDEHVKFFGTAVDTPSAASRLDENKQENDYWTSEPKDVQDERQKWCEEKVNFIAEVIPGVEKGSLRVQIQMCHSDTDVERLIVRLMEEGPPPNPPDIPQGYPPSLVSPDRPETSAFQPVERASTSAFQPFEQGSSNDSSPAASSSESQAAGEGSDEASGVEVEEKIMAHVATLCEMFSDADPDYLQERCVGINGDQTKFEGLVDELMEKKDYPKMEEYLKRQSVMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2H2</accession>
    <name>A0A423U2H2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000759">
        <property type="protein sequence ID" value="ROT82913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2H2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="362" mass="40897" checksum="5A224C88227017E8" modified="2019-05-08" version="1">MSFIPYYRCKIRLYNEVYGDIFKEGGEDKSRSGSSEGGAGSSTSKKDKRGNNKQPSTISFSIKSREQEVNLDRHSTFPVESSSTDDEDMEEEERERRRMEREERRRKRKLKEKEERERREREERERREKEEKERLMEKPDESTDASDDNEDVYDIFKYAQEMGKSTDAEEPQKPSKLNVESEKKDSDSLSATTAVLEDTHPFCQPERKQQERRKKAAMFLSRLKKGGGEEEAVNQPAYGPQLPPEIAAQILNSASQSPRSSVTSPRREAPAPPPPPPPTLSPVQSGHTDMFDPFTYKAGTAEASSALTYKNDRTSALESCIASGTDYIDTSKSTGLQESSVLSDVLQWLSAVDISSRAAVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9J4</accession>
    <name>A0A423U9J4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cornifin-B protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_015611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000295">
        <property type="protein sequence ID" value="ROT85380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9J4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40380:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40380">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="594" mass="63844" checksum="2BF5DD706AA5A538" modified="2019-05-08" version="1">MICKSPKLSDQQHIAPPQLCTHLHPPQLAHTCTLPSYAHTCTLPSYAHTCTLPAMHTLAPSPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPAMHTLAPSPAMHTLAPSPAMHTLAPSQLCTHLHPPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTSPAMHTLAPLPAMHTLAPPQLCTHLHPPQLCTHLPSPAMHTLALSPAMHTLAPSPQLCTHLHSPAMHTLAPPQLCTHLHSPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTSQLCTHLHPPQLCTHLHPPSYAHTCTLPSYAHTCTLPSYAHTCTSPAMHTLAPSPAMHTLALSPAMHTLALSPAMHTLALSPAMHTLALSPAMHTLALLPAYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTLPSYAHTCTSPAMHTLALSPAMHTLALSPAMHTHAASNSMQSLEYPCIQFFLRVCTELQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9J5</accession>
    <name>A0A423U9J5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_015742</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000297">
        <property type="protein sequence ID" value="ROT85367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9J5"/>
    <dbReference type="OrthoDB" id="79871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17681">
        <property type="entry name" value="RUN_RUFY1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.900:FF:000011">
        <property type="entry name" value="Uncharacterized protein, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047335">
        <property type="entry name" value="RUFY1-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004012">
        <property type="entry name" value="Run_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037213">
        <property type="entry name" value="Run_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45956">
        <property type="entry name" value="RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45956:SF6">
        <property type="entry name" value="RUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02759">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00593">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140741">
        <property type="entry name" value="RUN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50826">
        <property type="entry name" value="RUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RUN" evidence="4">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="371"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="255"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT85367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="48821" checksum="596551787FDEAF4C" modified="2019-05-08" version="1">MLDSDSVPLQHFFIVLEHVLRHGLKPKRGILGPKKELWDLFQMVEKWSYEAQDITASVRDLPTVKTHIGRARAWLRLALMQKKLADYFRLLIERRDDLLTEFYEPGALMLADEAIVIMGLLVGLNVIDCNLCVKEEDLDSQMGVIDFSLYLRNAGGEASPDDSPEQTDMTTVLDQKNYIEELNRHLNATVTDLQAKMETLTTTNALMKEDLAIAKNSILHLQEDNDRLRKDKGLPTQQQQEQLDREAKKASRISVIGCEEEMQDLKQQLEEESAHRKQVERELELQIQMKAESEMAAKLLEKDIHEKQDTIISLRRQLDDIKVINLEMYKKLQECESSLKQKTELIGRLEAKAAEMAETIRNLEAQYVFQGPQSSNDPSQVGHRARSKSYYGSVSNNEGDEKEEGEGHKAVGKSLSMSELQNRATGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA90</accession>
    <name>A0A423UA90_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_010239</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000230">
        <property type="protein sequence ID" value="ROT85616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA90"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="59"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="347" mass="39642" checksum="7CF1562112FB33F2" modified="2019-05-08" version="1">MASEVPFALTPFPQEAQAKIKAKFLGFSNGLVDVGGRHAMPAHYGLFANKYFNYKFQADDVLVMTFPRSGTTWTQEIVWTMRNQLDLDTAAEVPLDTRVPFLELDSIIPVHIRPPSGDAEGFWRLQPATNPLAKDVYLDQVDALASPRTIKTHLPFSLLSPDLVNSCKVVYVARNPKDVSVSFYHQQRLVKAAEYVGSFHEYIVDFWCQDHLLRAPYWSHLAEGWARRHHPNVLFLFYEDMKEDFLRELGRLNSFLGTGLTESQLQTVARHASFSGMKSRGATNPTAALQEAGSFKKGEAEFIRKGTTGDWTNFFTPDLEEKFQEWMEKWQPASREIPFKYHIAKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A2H4V3E2</accession>
    <name>A0A2H4V3E2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Actin T2</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Fast-type skeletal muscle actin 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_012597</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-08" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2018" name="Mol. Genet. Genomics" volume="0" first="0" last="0">
            <title>Actin genes and their expression in pacific white shrimp, Litopenaeus vannamei.</title>
            <authorList>
                <person name="X Z."/>
                <person name="X Z."/>
                <person name="J Y."/>
                <person name="J D."/>
                <person name="F L."/>
                <person name="J X."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <dbReference type="EMBL" id="MF627863">
        <property type="protein sequence ID" value="AUB30154.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A2H4V3E2"/>
    <dbReference type="STRING" id="6689.A0A2H4V3E2"/>
    <dbReference type="OrthoDB" id="6329694at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AUB30154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT69223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41954" checksum="6862DBEE2C5354CC" modified="2018-02-28" version="1">MCDDEEACSLVVDNGSGMVKGGFAGDDAPRCVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEESPTLLTEAPLNPKANREKMTQIMFETFNMPSMYVAIQAVMSLYASGRTTGLVCDSGDGVTHMVPVYEGYALPHAILRIDLAGRDLTNYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFEGEMNVAAASSSLDKSYELPDGQVITIGNERFRCPESLFQPSFLGMESSGIQETVYSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILSSLSTFQAMWITKEEYEESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQS3</accession>
    <name>A0A3R7LQS3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">JHE-like carboxylesterase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003931">
        <property type="protein sequence ID" value="ROT61912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQS3"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002168">
        <property type="entry name" value="Lipase_GDXG_HIS_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF12">
        <property type="entry name" value="CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01173">
        <property type="entry name" value="LIPASE_GDXG_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="3">
        <location>
            <begin position="225"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="46112" checksum="524E9852D0C70C35" modified="2019-04-10" version="1">MIVTPITTLNSSLFFSFFPIYPSLPTSPPYPHPLPIPPPLSPPPRLHPSFLPHILPIPPYFSSLSPPHPPLSPLHLYHPLSTSSPTPPLSLLPFLLHAFTLLPIPPSFFGLHPHPFSPSLPTSPPYSNPTPPSLPLSHPLTPSLFHPLSLPHLPHPSLPLLLSPPRLHPLPIPPSFFPHTLPIPLYLSSLSPHAFTTLSPHPHPLPIPPSLSPHALTPSPSPQPHRVSVGLPVLVYLHGGGYHGGSGESAPPHALLNEEIVLVVLQYRLGVLGFLSTEDDVIPGNFGLKDQTLGLRWVQRNIANFGGDPRRVTLLGQGAGAASAHLQMLSSKSFGLFSRVILQSGTALCPWALGGAHKQVADYTARLVGCSSDLGAHHLLQCLQAVPAGKLVHTIAEYFSNTYSPSLEEAAGEEVHQGCEAKSAEGGVTDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LS14</accession>
    <name>A0A3R7LS14_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative rab GTPase-binding effector protein 1-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_019283</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003534">
        <property type="protein sequence ID" value="ROT62852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LS14"/>
    <dbReference type="STRING" id="6689.A0A3R7LS14"/>
    <dbReference type="OrthoDB" id="79940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15739">
        <property type="entry name" value="FYVE_RABE_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.730:FF:000005">
        <property type="entry name" value="RABaptiN (Rab effector)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.730">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003914">
        <property type="entry name" value="Rabaptin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015390">
        <property type="entry name" value="Rabaptin_Rab5-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31179:SF7">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31179">
        <property type="entry name" value="RAB GTPASE-BINDING EFFECTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09311">
        <property type="entry name" value="Rab5-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01432">
        <property type="entry name" value="RABAPTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="388"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="463" mass="53284" checksum="8EBE4BC8A1283EA5" modified="2019-04-10" version="1">MVYVTPDSEGVTQSESILTPGDDDYVTIDLAAGGGSGTGSTGSRRVVSEVEWNLLNEEIRRARSRIGRSCQLCSNYQTQLQKIQSEQRETEKQKVDLEKALDRYREDLDREARYRHVMEDKWRTMAEDYEKKVAGVASVVEAATGKHNEVVAKFRATVTYLHDQLRVLTERREAAQQELTRLQKENDDLVGKHSQHSQQLQNEIINLPDNMEEMQLLLLRYREDIIAAKVSKEHLEETLKSEILFLKDQVLAEQHEKNTIEDRLSSEIDQLREKVAVLESVESQMKAERRSRAESDAQLKELENRQSEAQLKSQQIISALKTQVAEQTQARARLEAEVVELRGRVSALQHDLDTSEAVQRDFVRLSQSLQVQLEKIRQSEKEVRWQHEEDQEECNSCKQRFSAMGRRKHHCRHCGKIFCNECVSKTVPSGPHRRPSRVCDVCHTLLVQDATPYFSSEPPHSPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LST6</accession>
    <name>A0A3R7LST6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020172</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003877">
        <property type="protein sequence ID" value="ROT62001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LST6"/>
    <dbReference type="STRING" id="6689.A0A3R7LST6"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="29"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="30347" checksum="306BE2E230D91FE9" modified="2019-04-10" version="1">MAQQLANLFTRVGQIGFGVAVVGGVVNSALYNVDAGHRAVIFDRFSGVKESVMGEGTHFFIPWVQRPIIFDTRTRPRNVPVVTGSKDLQTVNITLRVLFRPRSSELPKIFTTLGIDYEDRVLPSITNEVLKAVVARFDAGELITQREKVSRNVSEALTERSAQFGLILDDISITHLTFGKEFTQAVELKQVAQQEAERAKFLVEKAEQEKKAAIISADGDATAATLLAKSFGEAGEGLVELRRIEASEDIAYRLSKNRNIAYLPNNQSTLLSLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTE1</accession>
    <name>A0A3R7LTE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003700">
        <property type="protein sequence ID" value="ROT62392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTE1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="416"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="776"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="803"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="817"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="870"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="900"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="910"/>
            <end position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="959" mass="96734" checksum="CFFFA56EF787FE46" modified="2019-04-10" version="1">MNEWAMNEGSAGRAGRGGEGGRAGRAGGAGSTLDTVHTDWAGERERGRSGESGRVRKRVRKVSQGGVRGVRGQVRGSQGVRGIRESGESQGRVRGSGVRGSQGRVRGVRGGVRESQGRVRERVRVSQGESGRESGGSQGGVRGVRGSGRSGESGESQGRVRGSQGRVRSVRGERGESGESGWSQGEGESQGRSQGGVRGEVRQGVRGSQGRVRESQGSQGSQGGVRGESGGSQGGVRESRGRVRGESGESQRESQGESGGVRESQGESGESQGESGWNQGESGESQGEVRGESGESQGESGGVRGESGESQGESGGSQGGVRGESGESQGRVRESQGESGRESGESSGESSGESQGGDQGRVRGESGESGESPVRRESGESGSGAESEARVRERVRGRVRGESGRESGKKSGGESGESQGRSVQGSQGEQSGESVRESQGGSQGESQGRVRRVRVRRGSGDAESGESQGGRRVRGAGGESGESQGGVQGRVRGESGERKSGESQGRVRGESGGRGRVRQEFRWQVREESGGVRGEFRGESGESHERSEKSGESAGESQGRSRGAVRGESGKSHGWKSGRVRGESGRESQGRVRGVRGVRGSGRVRGGVRGESAGEVRGESGGVRGRGESEIGKSGGRVRGEGERGSQGGQGRVRRRARRESQEESGESQGGVRGESGESQGRVRGEGRGQEGVRGESGGGRVRGESVRESVRGEVRGSQGSQGESGESGESQGSQGGVRAGESQGRVRGESGESGGSGESQGSQGGVSGESGGESVGVRGESGESQGESVDESGESQGRVSGESGGVSGESGGVSGESGESQGRVSASQGGVSQSGESQWRVRGESGGSGRVRGSQGGVRGGESPGSGGVRESQGRSVRGVSQGESGGQGSQGGVRGESGRVSQAESGSQGSGVQGGVRGESGAGGSGESQGGESGESQGESGGLHNDEKLKCSSGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXQ4</accession>
    <name>A0A3R7LXQ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014575</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Msh homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002820">
        <property type="protein sequence ID" value="ROT67340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXQ4"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048598">
        <property type="term" value="P:embryonic morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050674">
        <property type="entry name" value="Msh_Homeobox_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24338">
        <property type="entry name" value="HOMEOBOX PROTEIN MSX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24338:SF0">
        <property type="entry name" value="MUSCLE SEGMENTATION HOMEOBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="214"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="216"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="31"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="49313" checksum="A77828ECBAAD4114" modified="2019-04-10" version="1">MSGATVNSGAGEKPQSAFSAVVRKSFSSFSVDSILSGGGGGESRSARHADEGPDGEHRSPLSFPGTAHTAEFLLREERGGGGGGGEACKKDREGSEHTAPSSPGCEDDERDEEDIHVDTDPEDEKERDAAERLHAAAQPVIRPTALGPLQDPRLTGLGHPGPPPPHTLLPPHLQAGLWPSLPLLHHQLSLRALNKSPEPPRFHGPMKVTLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSASLNLTETQVKIWFQNRRAKDKRLKESEMERLRLASEPFVPPNPFLPPASLLPPFLLNSPFVQGLRHPSARRGAATHHLPAHVALTPAESFHWNLIFSSSLFSLSSPPSLTSPRFSPSSPPSPLFPLPSLPLPSHRISPPFPSFLSPPLPSPLSPPLPSSLPSFPFFPLPSSPFSPLPSSPPLPSSPLSPPLPLPLLSPLPFLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZ55</accession>
    <name>A0A3R7LZ55_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003530">
        <property type="protein sequence ID" value="ROT62881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZ55"/>
    <dbReference type="OrthoDB" id="10039395at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="481" mass="51458" checksum="CCBC3F3202F4B61C" modified="2019-04-10" version="1">MGSKAVSSHSFPRLAGQEAHNAQSSFDLHLFSGPGAQVVGGATGGMFQNVTGFSHELRQLPASAEELRQLSSARQFITSSGELRQLTSSSAELRQLTASSGELRQLTSASGEFRQLTSSSGELRQLASTLNSYPPLLFPGELQKMVSTGDLRPLLSAENITHLTLSGGEFRLVPVSGGSWHLISKSPSGLPPTPAASTKYPALPDTKAHPLATPSQVEAIPASWGSVQLQTCNVQLQQPLSMPTSDVGPLPALDSAMALSTTGAAPAGLAVQIANTQRQLHRPDHIRTSQPNPTHAQTQSPGNEVTRLTESAFKQDPQARLGNLQPSQSVLELEPPPLFNENLQAQSEACVEAHSPPSFMQIQPPPSFREPHLAYFEEHVPLLNSSEEHQYPQRSFDPTQVQLYTSETVHLDPSSGTAQVISANSESFQQPPGLQAAQRPIADEFRKFFSSMSQSSKSTPVPESIQSHSPSPAAKTPSLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1I0</accession>
    <name>A0A3R7M1I0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Actin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_012611</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002595">
        <property type="protein sequence ID" value="ROT69237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1I0"/>
    <dbReference type="STRING" id="6689.A0A3R7M1I0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.36.70:FF:000001">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.36.70">
        <property type="entry name" value="Actin, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0558">Oxidation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT69237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="18985" checksum="C4D8D539A5DAA62A" modified="2019-04-10" version="1">MCDDEDATALVVDNGSGMVKAGFAGDDAPRAVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWYHTFYNELRVAPEESPTLLTEAPLNPKANREKMTQIMFESFTVPATYITIQAVLSLYASGRTTGQVCDSGDDSTKCYIPRSIPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4P8</accession>
    <name>A0A3R7M4P8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase subunit gamma-1</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Mitochondrial DNA polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_014816</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
            <location evidence="2">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002846">
        <property type="protein sequence ID" value="ROT67122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4P8"/>
    <dbReference type="STRING" id="6689.A0A3R7M4P8"/>
    <dbReference type="OrthoDB" id="5588663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005760">
        <property type="term" value="C:gamma DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000024">
        <property type="entry name" value="DNA polymerase gamma, catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002297">
        <property type="entry name" value="DNA-dir_DNA_pol_A_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10267:SF0">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00867">
        <property type="entry name" value="DNAPOLG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="16">
        <location>
            <begin position="60"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT67122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="365" mass="40454" checksum="865FD181EC7C6381" modified="2019-04-10" version="1">MVIWNDQNEKTGKDILEANEKKECRTGIILPMVVTAGTITRRAVEPTWMTASNAYIDRIGSELKAMVEAPPGYHFVGADVDSQELWIAAVLGDAYFSGEHGATALGWMTLQGKKSDGSDMHSRTASTAGISRDHAKVINYGRIYGAGLRFIQRLLRQFNPKLSEEETQQRATQLFATTKGQKGWYLNKMGQNLALELNYPISGEALDRKEINKLLRQARYNNIEASFYDVVAGPAVWVGGSESHMFNCLEAIARSEEPRTPVLGARVTRALEAKYVDDQYMTSRVNWVVQSSAVDYLHIMLVSMRWLFQEYKIRGRFCISIHDERLIWHVNGGGAMGVTGDGSSQRSLGTAPWGPADQGVAGSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5C5</accession>
    <name>A0A3R7M5C5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008223</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002036">
        <property type="protein sequence ID" value="ROT73325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5C5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="43260" checksum="2A91C09DCBDBD411" modified="2019-04-10" version="1">MKGLSAVDVEVVLAGVPPSPLLPFRLSFSPPSFPLFLSPSLSLVIPSSFPFSHLSPSPLPLSLSHLPLLPSLFRPSSFPFSHLLSVPLPPSSSLSLFSPLPSVPLLPSSSLSLPLLPSPSLPSSSLSLSSPLLQSSPPSSFLSLFSPLPSVLSLPLSILSPLFLSLSLSPLPLPPLFFSPLPLFLSSFSPLLPLVPSSFSPSLPLLPLPSFPSSFSPLSLPLLSLPLFPSSFSPSPSFLPFSSVPSPPSSFLSSFPHFLQSSFSLFFPLLFSLFLQSSALLQSLFFPLLSSPSSIPPLSPSPISLPPSSSLFFPPPLPCSYLRRKLLCDLRHGEPHGEPGDERPEAGEHDGGGDVGDALPHGACGGVLVSLTEVWWRDGSGITGESRRCVGGFWYQWRVPEVWWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7E1</accession>
    <name>A0A3R7M7E1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative cell division control protein 45-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006523</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001827">
        <property type="protein sequence ID" value="ROT74957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7E1"/>
    <dbReference type="STRING" id="6689.A0A3R7M7E1"/>
    <dbReference type="OrthoDB" id="10258882at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902977">
        <property type="term" value="P:mitotic DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507">
        <property type="entry name" value="CDC45-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10507:SF0">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 45 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="556" mass="63667" checksum="1E5F0390841FEC6E" modified="2019-04-10" version="1">MLVSDLRKEFYDVIRGKRILVLAHFDIDGICASKILQSLFRTDHILYTVVPVKTRTDLINAYQQHAEQIKHIILLNCGGCVDIVDILQPPEDIIFFVADNHRPLDICNIYNADQVRILTKLGDDEEVPAFDDIFREDESDEEEESDEEGGKRQRFDEAALERRRARRQWEQQRHKILFDYTQFSYFGSSTASLMFDIAWKLSKDSNELLWWAIVGESELLMSDRIEQDKYLLVAAELQNHVSRLNHKSQDEQPLDCLRITFEKELQLGLYRHWSLVESMRHSLYTATTLRLWTLKGEKRLHELLAEMGLPLSQCKQKYCGMDVALRKELQSLLESKAEKYGLDNLLFASFTLSHGFRSKYSASDYVYATLALLETPEDEKTAADAFLDVSDSLSITKLSLLEKGIETSKQQLEAVYRQMQTFLDMNQVISAGPFLYATVIEGTPDAKFFSSPHCISLLARFTLRAHVAISRSKKSRSLPLIITTPDVKTSESNMCLVCGIPPVSEESPRNFFGKAFEQAADKTGSKAELEFFDTNIIRLSVDDRSKFFDALISLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MF35</accession>
    <name>A0A3R7MF35_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006809</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001862">
        <property type="protein sequence ID" value="ROT74681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MF35"/>
    <dbReference type="STRING" id="6689.A0A3R7MF35"/>
    <dbReference type="OrthoDB" id="30881at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT74681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="27615" checksum="5B5AF0E407AFFCA6" modified="2019-04-10" version="1">MCILTGLVVGFMLTLSSYVYLVDLMVFFVTSSRATKYKSSSKRKLEENFKEGGERNWVQVVCNGGVASLLAWLFIVDCGCGENPVDLVYKYRCSWLSIAILGALACCNGDTWASELGAVMSSGEPVLITSLQPVPRGTNGAVSTSGIVMSLLGGLVVGIGHYLTLLMFVSSPVMISAPAQWPIIIVGAVGGLLGSLIDSVIGATMQFSGMELGMDSNGKIVERPGDGVIPISGSYILDNHAVNLISSLLTALLLPRIALAIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MH04</accession>
    <name>A0A3R7MH04_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleolar GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MH04"/>
    <dbReference type="STRING" id="6689.A0A3R7MH04"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="155" mass="17501" checksum="DBDC236BD41F0901" modified="2019-04-10" version="1">MKEVHSLARKIREKIVINRINHTVDKPRKGNAVVPRASRPRERSVTRLKATFTDLGVDMTETEGCNFTRTSSLSRPAPKRFRSASATPRPRSLSTPRDEMGVKTPQEADKIKKRIRKAVHRSKNSVRGESDRHIFDLKPKHLLAGKGSLGSSNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHU7</accession>
    <name>A0A3R7MHU7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DEP domain-containing protein 1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001592">
        <property type="protein sequence ID" value="ROT76925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHU7"/>
    <dbReference type="STRING" id="6689.A0A3R7MHU7"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16206">
        <property type="entry name" value="DEP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16206:SF4">
        <property type="entry name" value="PROTEIN LET-99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="572" mass="63741" checksum="A1DF0E35750FDE13" modified="2019-04-10" version="1">MSTNTTGEYVTASAQSPMNRSRSAGNLECLGEDSCVFKATEAMFEQPQSIVPARSLASRIRDSIKRKHVRDDSVSRKKKNRSRDSKDTSKDDSGDYQRLDRLRTKSGGYMNLALAPVPNPQEDSRSVKSCVSDYQELGSVVSHIRTKSGGFLNLALEPSSDSVNRVETSDTFSGPPTSRSESSVQDHHSRSVSPLYGRLSQGDDQLTAPCTDFIRRRVITPDGCLSHSLSSSGCSVYHSALSSRNSTPNPGPPLPPKPLQPVSGMGGIYPKVNPKGTAPNYENVSDLSKQLSSSANELSDRWADRTPYGQVPPYAQGGVWRHYHSSPSKRLIGRKKGIENYYGSKACLPGLLTREGKEVAVSSIQLLLLLLEPVRRRKLHLLLRMMSKMSGNEKLCLDQEQTTRALVLNTFTRSILLCDQEADYDEVLSLRIISFLMDNHEEVLRPPQDLAVLVHRRLSEIQRSQIVYGSTVGDRGVTLTYCRQITNKEFERQRMTGSQLFLAQLLDQIVENDKLSSKEKKKKLKEFKSLYPEVYAARFPGEEQKVESRSKMKSLMKLASLSSLGKGRSLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI86</accession>
    <name>A0A3R7MI86_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyl-D-glucosamine kinase</fullName>
            <ecNumber evidence="2">2.7.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GlcNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_004129</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic-type N-acetylglucosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.59" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001549">
        <property type="protein sequence ID" value="ROT77234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI86"/>
    <dbReference type="STRING" id="6689.A0A3R7MI86"/>
    <dbReference type="OrthoDB" id="311172at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045127">
        <property type="term" value="F:N-acetylglucosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039758">
        <property type="entry name" value="NAGK-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12862">
        <property type="entry name" value="BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12862:SF0">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase BadF/BadG/BcrA/BcrD type" evidence="6">
        <location>
            <begin position="8"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="384"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="465"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="386"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="54863" checksum="650BB27318AB33E4" modified="2019-04-10" version="1">MSECQTRIKQLVDDAKQMAGLPQDTTLEGLGLCLSGCEDEEGNRDMAAALMKRYPDLARHVIVSSDTKGSIATACQNGGIVLISGTGSNALLLNPDGKTYRCGGWGHLLGDEGGAYWIAARAVKLLFDEDDNLIDPPFNTAQLRDIVYTHFELKDRGSLYSAPFSHCTSHYKPGRPMLGQATNKDFATHLRKQTAYEERIHIDRFGMLQHCYQSFEKAKFASLTAKISQGASNGDAMCARILYDAGFALGRHIAALSRNIHEALLFTEDGLQIVCSGSVWKAWEHLRPGFVDGIHPRCEKDRVIPKYTLLRLAIASEASFFPHPFPSPFSLPPLTTSWTLPGRWGPLVPRRRPALLEETALGPVHLASLEADVDLDGVSAQLGEGTLSSSRSEPAAYSLTSSRGSPSAWHTQARTSPTVCSSAFSTTWVVLERTKNLMLLAGADDAGVGEAWVLARSNLAGGERAQLGLNSHPLGKSPSASDDQRPQASSPREPGPSRDTKSTHKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIH4</accession>
    <name>A0A3R7MIH4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Core histone H2A/H2B/H3/H4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_003922</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001525">
        <property type="protein sequence ID" value="ROT77430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIH4"/>
    <dbReference type="STRING" id="6689.A0A3R7MIH4"/>
    <dbReference type="OrthoDB" id="10250585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000024">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="59"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT77430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="151" mass="17048" checksum="6347DA9481505405" modified="2019-04-10" version="1">MHTFPSASGRAHLGKRWPAPSRRPRKSTGGKALVSSWPPRPRKSAPASGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ12</accession>
    <name>A0A3R7MJ12_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Reverse transcriptase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_019140</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003509">
        <property type="protein sequence ID" value="ROT62995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ12"/>
    <dbReference type="OrthoDB" id="6379141at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="10">
        <location>
            <begin position="102"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT62995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="50321" checksum="EFB3EDE1087221BA" modified="2019-04-10" version="1">MALIHQSGARMHAAPALVSTPLIYTVLPRTCAFKNILREFLALTKPINRATQPDFLAHYDLTVNLQEHPAGIPGLDQADQPGHPTTARGPSPHRDSRCRPLAPDRCRSTKAEFDHMMQLGIIRPSSSQWAAPLHLVKKDGDWRPCGDYRHLNTITAPDRYPLPHLHSFSHELSGCTVFSRIDLVRAYHQIPIAEDIPKTAVITPFGLFEFLRMPFGLRNAAQTFQRFINDMTRGLEGVFAYIDDILVASASEADYARHLCALFGRLQEAGVVINPGKCLFGAASLSFLGHTVTSQGPAQEKGQQKHQNQVDAPTNEAFETCKEALASATLLNHPLPEAPLNIAVDASDTAIGAVLQQRQVRHFQPYVEAKEFHILTDHKPLTFGLHSRTRRQSPREERHLDYISQFTTDIRHIRGADNEAADALSRVTIAAATPPTTQWITTWSAVNNARTHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLK7</accession>
    <name>A0A3R7MLK7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003176">
        <property type="protein sequence ID" value="ROT64861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLK7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="54945" checksum="A9680F089B1A723A" modified="2019-04-10" version="1">MLSSSQSPPLLPFFFPYIFLFSPLFFYPSSFHLLLTILSFFVPSLSFYSFPSSSSTVPYPHLFPPSTPTTASSLSFPSSLSSFLPSIPSPLPLPLLALSFPLPPIFSSLSPTSFPNLLPSPRPSRTPFSLPQPRSPPPLHQPPPPPPFLFPQPPPPPPSSPHLPLSPFFPQPPPLPSYPQPPPPSSQPLPPFLNPNPTPSPLAFPHPPPPFFPQPLVPPPAPPGQRLIFLMANTAPRPQAPKIPPPPSRRRRRPHLREGVRLARPPPALRFLLLSSLSSCGPPFTFSFSSPLSPVPPFFLSSPHCASFFLPSLLVSLFPSLRLFLLSSLSFPSPTAPLFPLFSLSLLALFFPLASSTAMSFPYLLLHPCASFPLLPSPTPLSPCPLFTSLLSPSALLSLVSSLPSASPYPSLTSPLLQISPCNLFSFSSFPYPFILTPSPLCAFFPSSSSLPSLAPTPSPSYASLSPLLSPHPSASVLLPLLSSLPLLLFPLSPHTQIWPLLHSHKAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MRI3</accession>
    <name>A0A3R7MRI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Putative neuronal acetylcholine receptor subunit alpha-7-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_022753</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Postsynaptic cell membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000599">
        <property type="protein sequence ID" value="ROT84060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MRI3"/>
    <dbReference type="STRING" id="6689.A0A3R7MRI3"/>
    <dbReference type="OrthoDB" id="6365956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045211">
        <property type="term" value="C:postsynaptic membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022848">
        <property type="term" value="F:acetylcholine-gated monoatomic cation-selective channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18997">
        <property type="entry name" value="LGIC_ECD_nAChR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19051">
        <property type="entry name" value="LGIC_TM_cation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.170.10:FF:000028">
        <property type="entry name" value="AcetylCholine Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002394">
        <property type="entry name" value="Nicotinic_acetylcholine_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00254">
        <property type="entry name" value="NICOTINICR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="15 17" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 17" id="KW-0406">Ion transport</keyword>
    <keyword evidence="14" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="9 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0628">Postsynaptic cell membrane</keyword>
    <keyword evidence="11 21" id="KW-0675">Receptor</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0770">Synapse</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 17" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="353"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="574"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="19">
        <location>
            <begin position="148"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="20">
        <location>
            <begin position="359"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="21"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00034104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT84060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="631" mass="70646" checksum="3AD5278484A8A156" modified="2019-04-10" version="1">MFQFATLVSFHILCKPRVSLHHRPSLGRDRPRGNAPDGRPRGDPGLYYLEDKVGGRGKQPATHPVLVGGFREKTCSDAASYGQGAPSGRPDAKDSGTAGSDGRGGAHRQGHAVVGEGSTHAEGIGIGDGGSGQDEVLHVGHSPSDQHLLYDDLFKNYNKHTRPILSHDDIITIHFEIALFNVLNLDSKAGVMETNTEVILIWNDPYLKWDPDYYNHTTVLRVPYDLVWRPDIILYNTADKNYEASLIYTNVIVEFDGTVKLLIHAIFTSVCAIDIQWFPFDQQTCDLIFSSWTSDINQVLLEMGPSDITRYQPNHEFFLENFWSETMVESDPCCEEPFSMVTYHVQLQRRVKFALFFFIIPGVLINMCALLVFLAAAETGEKVGLGINSMLAMMVFLMAMTENLPPTETLLWLSDICQKPRLAPPTCVYYGVCLVVLTCNIGFSVYVLNLSYSGDRGYEIPEWVRTLVVMATRVICMKVPGFIIKQWGLDENSVSAFDLDSEFKGMRVNVIKVNARSKSDGAAMLKDEFQRRSVEALESIQQHMEEQTLHYEDTQRRTRLVEEWKFLSRVLDRVLFILFGITTFLFNLIILTQSPFGEKFEYCPLGPGLCSDGYSFGSTADFGSNGGGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MUU9</accession>
    <name>A0A3R7MUU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002445">
        <property type="protein sequence ID" value="ROT70291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MUU9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="44425" checksum="10A7FA5F9FD72829" modified="2019-04-10" version="1">MSSLSTLFHHSCHHFSTIHIIIISPLHHHRSLRDPGRAFPEGSYAPPGRYVCIKIYFARGHSHQPGQPADPRPALTVWSVTSPAAGQSGSGSRTGTRGMAALVGCGGGVEAVSTLVHCRECAREYGGARQAGRAGSLPPPAASSTATLQPHPPTRPHCDLRLSHTRVRMAGLQPHPPILQRHLLILQPHPSILRCIRLCYDRTDDVATKLPPLPMTTMLTPLAPTPTWQRTLLALQCLLLRPPCSPRQSTSTTPCRSGILQFILHRAPTYTATASINTASAPIHPCCNCIHLQNGLVQPLFQTPHVTATTTNSHHDHIRHSNLAPCCKRLKARHSSHAENRRDTKPASKSRPSTRRSTRNAPTSCHIASPPLCHRTQHTHGSSMHHTLKLLCNHIPSVNSITHEHAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NB10</accession>
    <name>A0A3R7NB10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_024599</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000855">
        <property type="protein sequence ID" value="ROT82235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NB10"/>
    <dbReference type="OrthoDB" id="6373312at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018701661" evidence="14">
        <location>
            <begin position="23"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="595"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="15">
        <location>
            <begin position="231"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT82235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="623" mass="72232" checksum="A7273830E7E3D669" modified="2019-04-10" version="1">MGIASGILLGTILLLRLLLIHANLPSLATKITNPGTSLHLQTLQELLRGPLHGWKTVLYFDPSLGVEVLDRLFRLQAFRTNDHVLVNLEHDGDQWSQNQTSAVLRGGHMVHVVVFQEDFRPFFDSVSLQWNPKYLVVFPFTKTNIKKVLQYEGFKGPEKIVLLGSSERTNELKARHINVYTYFPFARENPIRLLGPWNTETFLSFESIFVDRFPSFEGYNFWLGTWFDDYPYLHQSKTGPEGEGDGVEVEMLDAMARRLNYTYHLTTEPPDLNWGDFENGSWTGMLGMVHSKDKNFTVNYFGYTNERIEAFDHSVSYWNEGFGLALLRPPPLPKWRSVYYPFTLEVWASVTATFVLTVIVMLIQDMLQPEPFLGGVGSTWPYLLRAMFNNSIPRLPKAHWQRLFVGSWWLYCFILTTAYTANLIAFLTIPVFPGRIQTVQQLAESDYRVSMYDYGEFVAGALRTSKDPHYRTLGERLDLHSTDDESMYPVLNGTHAYIESYSYSVVYIFDRYKVKNAYMLREQLYPGHLCWYFQKNTAWKYKFDEAIQHLVESGLIEYWLKIKTEDFLGTDFERKEKLSSEERSNTAISLEHVQGVFFLLLIGWAASFLTFLAEFLTKSAKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P0H3</accession>
    <name>A0A3R7P0H3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002224">
        <property type="protein sequence ID" value="ROT71945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P0H3"/>
    <dbReference type="OrthoDB" id="6085656at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018654916" evidence="1">
        <location>
            <begin position="18"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="205" mass="20014" checksum="3E8CAAD89A4E138F" modified="2019-04-10" version="1">MKVYVILALVGAACAAALPLEAPEPVQDTEEVVQARAEFQAAFAAAAAAAAADEVPEVVVPEGAPEPVVDTEEVAAAKAAHQAAFDAAIAADGSLPEVVVPEDTEDVAAAKAEFKAAFEAAAAAAEAAPDAPAATVYTAAGPVAIHAPFLAGAPFVAGSPVVSGAPLVTGTHVVGGAPLVYSGLGFPAAVPFGLHGFPFVQVAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P309</accession>
    <name>A0A3R7P309_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001947">
        <property type="protein sequence ID" value="ROT74052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P309"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="417" mass="44277" checksum="8F7EE338141386E5" modified="2019-04-10" version="1">MSVNAYLIASHGRPLIAIATSFLSSFHFVLITHFASPSSLIFPYSHLPLPHPPPNPSISKLAPPPPSPPPISSPSPLSPLRPNPLVGTTSASPACCAPPTACCIALPPACCFLAPSCFTLSSLLLFSVPSLLLLSHPLLPASCAVPPSCLSFLSLSPLLDPSLPLACCFSPSCFATCPPSCFFSVPPSCLLIHPSFLLVALSLPLLLSCPSLMLADPSLPHACCSLPPSCFLSCPSLLLVAPSLPPACLSRPSSCYLLVLPSSCCSSFPCLFPVFPSCSLSFPSFLLTVPLPSACSPASLFPTGCLLLFFPTCPVPPPFAVLPSCFPPSLLRPSIPHSGRCVFFPSFKRFSYNHHTPFTSGSVVYSAGHSAPYNAKQRINRSHHTSQSISHYHTTTKNHIYHETHFKAPYLIASYFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9Q5</accession>
    <name>A0A3R7P9Q5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PAB-dependent poly(A)-specific ribonuclease subunit PAN2 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001236">
        <property type="protein sequence ID" value="ROT79481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9Q5"/>
    <dbReference type="STRING" id="6689.A0A3R7P9Q5"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000421">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050785">
        <property type="entry name" value="PAN2-PAN3_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048841">
        <property type="entry name" value="PAN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728">
        <property type="entry name" value="DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728:SF0">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20770">
        <property type="entry name" value="PAN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAN2-PAN3 deadenylation complex catalytic subunit PAN2 N-terminal" evidence="2">
        <location>
            <begin position="59"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="535" mass="59633" checksum="999D35FE2B5F288F" modified="2019-04-10" version="1" fragment="single">MDFSAVQFGEEMLGYDGSNTFSEEGTAYAEIYGGEGGEGFPAGGEFAHDSQEVEFMNGGDYQESQTVLVDGGDRFGVSAVTVDRKEELVWMGNSGGHVTSYLSTELMKYTSFQVHATEEIRDLRSTDAGVLALTPTSLNLWTRQGIPVFSHRSPQLENMQCMLQLGGNFSHRLLLGGHQGSMVEYDLTRQEQTRCHQVGEQGCVILRDHARFVCHGDLTGRIVLHDPRTMRQEHYFQAHTGSLSDFDVLGNYIATCGFSNRMGQMMGDQFVMVFDLRMMKLSLPLRALVPPFLLRFVPGLSSCLAVVSPLGHWQLMDAGQPDNAIMSMSYQVNCSPESVITTFDVASSSQALVFGDNLGSLHLFSTGNKPTFNNFSQETIMPDLPEQVQTMPLTDSTSSIASLPMYYPTSALLSDWPEQYMRARYRPTPPVDPSILASMKIVGSIGYAPNLHNRKRNQVPYKFSRNKGPKSNSNENSTGKNEDGIAVHVPWRYRKMEIKYSKLGMDDFDYDQYNRTSFSGLDMSLPNSYCNPMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PD09</accession>
    <name>A0A3R7PD09_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E3 ubiquitin-protein ligase E3D</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HECT-type E3 ubiquitin transferase E3D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">UbcH10-binding protein with a HECT-like domain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2C-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_020328</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Independently of its E3 ubiquitin-protein ligase activity, acts as an inhibitor of CPSF3 endonuclease activity by blocking CPSF3 active site.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with UBE2C/UbcH10 (E2 ubiquitin-conjugating enzyme). In vitro, interacts with cyclin-B.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003969">
        <property type="protein sequence ID" value="ROT61864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PD09"/>
    <dbReference type="STRING" id="6689.A0A3R7PD09"/>
    <dbReference type="OrthoDB" id="10264956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019193">
        <property type="entry name" value="UBQ-conj_enz_E2-bd_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31531:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31531">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09814">
        <property type="entry name" value="HECT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00053831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00064185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT61864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="42574" checksum="8B949F3314A3541D" modified="2019-04-10" version="1">MCIVKLKNGDDLNIKFPRGTSLVPGTVSKVTQDGSHITARAQLDEKTSLLSTLSADLLSNIGPVISDSSPTFSEILKDSLVTAQCKQCRKVLLNDVRFRRVLPLPSVDWDQASEGWFCHLHGSEGEKLKPSSLQPASDDCFYSELHFLIHKDAAVDCVAPNDNKCELTCCGCQASLGIRSKESALKLWAHSLMWVRSEDKQILFGKDVSGILLSLIHNIDKDNFGVNCRLVLKVSQEEEAAAEPEFLYLVTMNTNQKLLLPEGSSLSGISDKKYSLSGNFYKMEADSLASDKSFSSEKRPRVHQSDISEVILRRLYTIKLLYLLKRGEDDLTGSWVDDVNVHILPCSRSFLLEVKDVLEASTACLPQAMRKVENMSVGYIAKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDK9</accession>
    <name>A0A3R7PDK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000769">
        <property type="protein sequence ID" value="ROT82843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDK9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="43647" checksum="4A3137F42E13B4A3" modified="2019-04-10" version="1">MLRPLSDWVGGGAEEGVASPLLLRVPSRMRCLRPATRSAPCPAPEVQESFILTFPHPALLLPPSCTSARLLPVRAHRLPAAALLQNPAAPSGTPAHSCRSARSTGAAALTHSAFPTPSHPLPPFPTLSTLILPLPIFSTLFHSFHFPSFFPIPHPFHPLPLFPIISHPLPLFPILFHPFPHFHTLPHFFSPSSILPHSFPPSSTLFHPFPLFPSSSTLSHSLPSFSTLFHSFPLFSTIFHPFPTFPHFPISHPLPPLSHFPLLQPFPHLLSPLSSRFPPSPTLFPLPLSPPFPPSHPSPHPLPPSSHPSPLTSTLAHFFHPLLSRPPFPPSTLSPPFPTSFSNSDPLTPFPSPPFPPSPTLSTLPRPPPLYQTLMPRKSSLLHLPSHVLIGQKATPKTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDW9</accession>
    <name>A0A3R7PDW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000729">
        <property type="protein sequence ID" value="ROT83141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDW9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1030" mass="120573" checksum="AE5342F4BD5E78EF" modified="2019-04-10" version="1">MIPRLSTTNKYCFRYHDYQYHKTSTASDTTTVVPQTSTASDTTTVAKYHDCSTTNKYCFRYHDCSTTNKYCFRYHDCSTTNKYTTTNKYCIVYHDCSTTNKHCFRYHDCSTTNKYCFRYHNCSTTNKYCFRYHDCSTTNKYCFRYHDCLATTNKYCVKYHTTSSRNNTASDTTTIVPQTSTASDTTTVVPQTSTTLDTTTVVPQTSTASDTTTIVPQTSTALDTTTAVPRQYLNKHCFRYHDCSTSNKYCFRYHDYSTTNKYCFRYHDYSTSIKSCFRYHDYSTTNKSCFRYHDYSTTNKYCFRYHDYSTTNKHCFRYHDCSTSSKYCFRYHDCSTSNKYCFRYHDYSTTNKYCFRYHDCSTSNTYCFRYHDCSTTNKHCFRYHDYSTTNKHCFRYHDCIPTNKYCFRYHDCSTTNKYCFRYHDCSTTNKHCFRYHGCSTSNNYCFRSTVVPQTTTDTTTVVPETSTASDTTTAVPQTSTASDTTAVVPQTTTASDTTTVVPQNKALLGYHDWSTTNAPDTTDCNLKQYPLNHKQARLHYPLDCFRYITTTLLTTVILTASDTTTVVPQTSTASDTTTIVAETSTASDTTTVVAKTSTASDTTTVVPQTSTASDTTTVVPQTTADDCSTTNKHCIGYHDCSTTNKLCFRYHDCSTTNKYCFRYHDCSTTNKHCIGYHDCSTTNKLCFRYHDCSTSNKYCFRYHDYSTINTIRYHDCSTTNKYCFRYHDHSTTNKHCFRYHGCSTSNNYCFRYHDCSSRNKYCFRYHDCSTTNKHCFRYHAVVLNNCCFNIHDCSTTNKALHRIPRCSTSNNCFRYHDCSTTNKHCFRYHGCSTSNNCCFRYHDCSTTNKLCFSYHDCSTSNKYCFRYHDCSTTNKHCFRYHDYSSRNKHCFRYHDCSTTTHKTRSTTTTASDTTAVVKQHCFRYHTYTTNNKTNAAYHDCSTTNKLLLQYHDCSTSNKYCFRYHDYSTTNKYCFRYHDCSTTNKYCFRYHNCSTTNKYCFRYHDCSTSNKYYFRYHDIVPQTSTLQIPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFA5</accession>
    <name>A0A3R7PFA5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium channel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_021422</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000449">
        <property type="protein sequence ID" value="ROT85080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFA5"/>
    <dbReference type="STRING" id="6689.A0A3R7PFA5"/>
    <dbReference type="OrthoDB" id="297496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015271">
        <property type="term" value="F:outward rectifier potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022841">
        <property type="term" value="F:potassium ion leak channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030322">
        <property type="term" value="P:stabilization of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003280">
        <property type="entry name" value="2pore_dom_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003:SF330">
        <property type="entry name" value="POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11003">
        <property type="entry name" value="POTASSIUM CHANNEL, SUBFAMILY K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01333">
        <property type="entry name" value="2POREKCHANEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="129"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="11">
        <location>
            <begin position="218"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="560"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT85080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="681" mass="76574" checksum="DB7757564E338335" modified="2019-04-10" version="1">MSRAGKRSGIWLALSARRAWRRDGGQQCLRPGSIGEAVQDIYQHRLGQLASAGDALEELLELRQHILQLCPHPVINGTFGLLESNGESESRGQAQGSAAHQDKLGLGADWSSAVEEECQESLRIIDHVTKVEKWTLVDSIYFTMTAVTTIGYGHISPATRYGRLFCVLYSLVGVPLTCILMAYSSEMLSNRMLQLYTSARKRHQRHRKTLLYGITWIYLSVGFIVFMFLPSLALSKLEDWSYEDALYYTFITLSTIGFGDLVAGYRKDQPYSEVYKLAIVVWIMMALGYWFLLLNFLQKALKSNVPRRIKKTFRSKRIAKQAEFFRQLVGRVKLGQRKASLVDGDRGVVALMVEVAGAFVGDEPGRTSRKQSLRIDCTQGNDDSDSEANEPLTLSDLLDVNVVLRSDSMPAIRNLAVENFPDEVVLPLREVLHLVSLVASVEEQVHNTCADDDATACSSTTLQEDPTDSTPSIVTFDPRENVPLLRDIFHYKHNHHAKSAFCNGIKMKSRMRTLSQREEEEIDEVLNEVFDAGRRAQDTAGRRGWQLLHARQDRLRAQEVGAAAAREEESPQDATRAAGRRATLKQPFWPRTGAPRSLSRRDAQDFHAASTSPSRASMSASLMDIFINGFLRVRPRHAFFFSQASRREGGRPRRSWTPVIACHVSFCRCIPCALICICQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFM5</accession>
    <name>A0A3R7PFM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003167">
        <property type="protein sequence ID" value="ROT64938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFM5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="897"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1067" mass="108042" checksum="92C564E180457571" modified="2019-04-10" version="1">MLVSPPPAARGERRDATSAEALTWLKQQMAIIRGESYTTLGKDVLACCAWLLSSGQDILGWVGLGGAVSESRSKTNPSCFSPAGVDLFPSSFQAWPGGRCGPPRCPSAHPLPSRRPPLPPPQTLTLSLPDGPSPATPDPDPHPSAASVPDTPSSAAPAPSTPSPATLPPSMTFNSSTTSAKSNPASPLPSETSASLTTLLTSTLSSSTLSTAAPSSSTTLGLAATTETFPVTDFVNSTSSGATSMLPVTTASAGVSDEPSPGPVAPVFYFGGVQASQSKEGGEGLLRGEDLSQDLQEGDLQHEGGYQDVPHQPKMSEVFSKPFLWLGTTEQPTTPVVPITPSSRLSTTHWYDYLLNHVTQNAAFPSGFDQSQPFLRPTVRPPLFLRPSTSPPTFDLRLQGRPPIPFAEHGPPPSEGRDPALSAGEAFHTSLDPGLASLLQWLPQGTSFQGLPYVPEVSTGFPPTSPSPQRSEVVSSAPPFPQGPPGAHTPSALFLSFTPAPRPPSAPSGPPQAATGAPPDASFYPSLSPSVVLRSQDSARLPAGDPPAAASRSEPDAGRLPQRPPGGVQAHRSLPAGRRRGGTWHGPPTPPQAVLVGGDVNTLVKAPGHFHGEKGEPVKNMFPDNYQVRFPIQVGHGAPGLQVVTPGAVAGQQVVPPAGVQANQAYFQVASPHNFQVKKPESVQIRNPGPIQIRYPPQLQVVNPSQSQVAKPGQSQVTSPNQYQVVKAGQSQVAIPSQSQVANQGGLPIRAPIRLQSSPAGSERQANGTNYPFDLDLSSLDVAYLVYPQYEQPPETTPLPPPATSPSSSNMEILYPLLGLGQNQLQNQSQSVVNEVHSYQNLVIQLANGTNITTVVVSSSSSTGDGNTGGENDGSDAGIYNGSTQGPASVGSSALSGGSGGGTAGGTASGADDGGTASGSEGGADGGTTGGISDGGAGGGSSGGGTTGGSADGTSGGSSYGGTADGTAGGSSGDGTTSGSSSGGTVGGTAGGSSGGGTTSGSNDGGTAGGSGGSLPSNPNYLPHPEIPHVTTPPHSLPSPFKHPCPAPPSNPLPPSPVYRCNERGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG41</accession>
    <name>A0A3R7PG41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative laminin subunit alpha-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000034">
        <property type="protein sequence ID" value="ROT86039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG41"/>
    <dbReference type="STRING" id="6689.A0A3R7PG41"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000034">
        <property type="entry name" value="Laminin_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00052">
        <property type="entry name" value="Laminin_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51115">
        <property type="entry name" value="LAMININ_IVA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Laminin IV type A" evidence="5">
        <location>
            <begin position="49"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT86039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="21519" checksum="BA0E094066514638" modified="2019-04-10" version="1">MHTVSPTIPLHPLPLAQPPLQLRTTEHRVLNIEYRRPGHGERPFRPPVVVYRPWNTQEICYINLALPGERLLSFGEGETKLNVTNQLHVIPGTEGNVKIGSNQLFDAPLYWQLPREFMRDKVRSYNGYLRFRVHSEGGSRNFPEQILQTYPLVSLQGNWQLVLEYYPPAIASDGRYEVKLHEDYCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGQ0</accession>
    <name>A0A3R7PGQ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-2-macroglobulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003012">
        <property type="protein sequence ID" value="ROT65961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGQ0"/>
    <dbReference type="STRING" id="6689.A0A3R7PGQ0"/>
    <dbReference type="OrthoDB" id="9998011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.690">
        <property type="entry name" value="Alpha-macroglobulin, receptor-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009048">
        <property type="entry name" value="A-macroglobulin_rcpt-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036595">
        <property type="entry name" value="A-macroglobulin_rcpt-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050473">
        <property type="entry name" value="A2M/Complement_sys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047565">
        <property type="entry name" value="Alpha-macroglob_thiol-ester_cl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412">
        <property type="entry name" value="MACROGLOBULIN / COMPLEMENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11412:SF171">
        <property type="entry name" value="PREGNANCY ZONE PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07677">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01361">
        <property type="entry name" value="A2M_recep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01419">
        <property type="entry name" value="Thiol-ester_cl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49410">
        <property type="entry name" value="Alpha-macroglobulin receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-macroglobulin receptor-binding" evidence="1">
        <location>
            <begin position="503"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="602" mass="66974" checksum="89C5BB5972A9031D" modified="2019-04-10" version="1">MLELGDVNLTVISAVDYKIPVKCETGPSSEELLISHGLSSSFISYRDTLIKSIKVEAEGFQKEKTWTRYVCTEDLAKGDKLKSDQLSTSRNTVEGSERAWVTAEGDLFALPIETMDSLIRVPHGSGEQNMVIFAPMVHVMHYLKDTGRTTENTKKILRFLRIGYRRQLLYRRSSGAYSAFGNADRSGSTWLTAIVLKSFALAAEFITIDIPALKETSRWLSSSEIEDGCIVPKGKVIHKGLKGGVSDKNSSVPLTAFVLAALLEAGARTNMSIVKGAIRCLLSERSKDPHTMALKAYALIMAENRGGKDLLRKLLALAVEKENVLYWKPLEGTSWSKSQAIETTGYAVLAMLNQDPDKYKLLAKKAIQWLCGRRSSKGGFWSMQDTTVALQAMAKYETHSNREPTNVRVTFKARSFSATFNITNKNKLLQQRQELPVLPTDVDVTLTGRGCAIVQTVFHYNVPEAEPSDAFSLRVHPTNDPDGGCKEKRIEVCVAYLLPDGKSNMAVIAVKPVSGFSPETDDLKAVVRRNPKVVKRYGVDGNIVYFYIDKFTAKEVCVSFRVVREVEVEDAKPGSVVVYDYHEPEFYVSQTFQFRPMEGCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPA0</accession>
    <name>A0A3R7PPA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001398">
        <property type="protein sequence ID" value="ROT78354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPA0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="569" mass="60102" checksum="3BB97C9CBA620D3C" modified="2019-04-10" version="1">MKRRSEAASGRLGRARGPAAVERLRAPQRRLCALADDDGDGWAEGERARGGGHEIIEPPRRRFRCPSSFLEGAAPAEAARVGVASRCLGDGRRRESGRPTVLLRLRSLGLPSPPSHERAARKVLLVRGSEQLLGSRQLRRDCRSRDAPEQRRAALAGASRRRADSASNEVACPGGSIFPNVYLRIRPSIPPPLSPLLSSLASPPHPLPFLTPSFPSSLLLSPPPIPYPPLPSPSPLPPPIPYPSSPLPSPLPLPFLTPPPSSLYSLPPPSPLPSPLPPSHSLPPPSPLPSPSSPPIPYPFLPLALSSPIPYPLLPLFPSPPLHSYPSSPSPSPPLVSHSLPPSSPLPSPLPPPIPSPFLPLAPLPLSLPIPYPLLPLPSPSLSSPSIPYPLLPLPFLTPSPPSPSHSHSLPPSSPLPPPIPYPFLPLAPLVSHSLPPPSPLPSPLPPPIPYPSSPSHSLPLPPPSPSHLPFLTPSSPFPLPFLTPSSPLAPLLPFLTPSFPSSLTSPPPIPYPLLPLAPLVSHSLPPSSPLPFLFPLPFLTPSSLAPLISHSLPLLPLFPLPFLTPSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPH3</accession>
    <name>A0A3R7PPH3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002078">
        <property type="protein sequence ID" value="ROT73041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPH3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="463" mass="50948" checksum="8C59066A9A39A8A0" modified="2019-04-10" version="1">MLLSHLFFPPFLACSLSFPPCSLRLFSLLSPSTSLVLFSFPFLRLLICLLPLPPRLILSFPLPSLVLSLPLPPSLVLSPSLFRLFSSPSPSSSLDLLSPSSRLFSILPLLLACFLSFPFLQSLVLSPFPFLPRLFSLPLPPRLFSFPSSSLAFLALLSLIPRLFLSFPFLPRLFSPFPFPSLLPSLLVSLLSPSPSLFSLPFLAFLPLLPRLFSLLSPFLRLFSFPCSLSFPLHPRLFSLLPSSLACSLSFPLPPSLDLSPFPFIPLLFSLLSLIPRLFSPSPSSLAPFPPSLVLSPFPFIPLLFSLLSPSSLFYSLSFPFIPRLFSSFPFLPPLLSLLPRLFSLLSPSSSLVLSLSFSPFPLLPFVPRLFLSFPFPSLVLSPFPFSSLVLSLSPSFFSFPFSLACLSPFLPPRCSLSFPFSSLVLSPFPFLPRFLSPSPSSSLVLSPSLPPLLSLSFPFLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQF7</accession>
    <name>A0A3R7PQF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001247">
        <property type="protein sequence ID" value="ROT79422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQF7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="41457" checksum="93F7FA1A0D10453E" modified="2019-04-10" version="1">MSASHPTRSARRQALLPAKNYPESEPRRPASPRASRRSAGEQDTSPSCESTCVHCFSPVCSFSCLLSSVSSSLSPFSLDLVVILPHQLASIPLPDPVPRTLHATAAAALCQGARGAAVSGTFKHHTSAADMDSISGKNKLPSLGAKSVRISLRFRNSRMWREVVDFYFSATEGGGGASVSSPLHPGNVLGVFARDPPWIPFSAAGTGSRFLASGSAGPLLFPATAPPSVGQGRLLLDWRGLSNDAASGPLASEAEVPCTACEAGAGGVEASVSNRCRLACLAAIVFTRPRPRAPLSPLYIPPPRVLARLLFLLPCAHIPRASRPSSSLPLLPIALPHSCTLSQGTERMGARSAVSFLLADTPGDPKRTPRAAAICCTAAPATACANPQSAWSVGGHGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PX12</accession>
    <name>A0A3R7PX12_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Proline dehydrogenase</fullName>
            <ecNumber evidence="1">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001185">
        <property type="protein sequence ID" value="ROT79822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PX12"/>
    <dbReference type="STRING" id="6689.A0A3R7PX12"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="252" mass="27677" checksum="37CBAA3198229B65" modified="2019-04-10" version="1">MRTRLPAMASAPEAGVRLTSRSPRSIPGVRACHVAGTGNPPQSTIVLRSTLAWRRAFRNCLVLARPSAHWHASCRGQSAGALGVTCAVTSPTHRHMWRSTNDARPIGALGIRYKSTPAAASLVNENAAVDTASQDDKDKDPLDLTFCDYRNAFKSKTNSELLRALLVFHLCSIQPLVDNNAKLMKLGQKVLGKRLFAALMKATFYGHFVAGEDQIKIQPTLERLRSFGVKSILDYSVEEDISSEDAEEREME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXY6</accession>
    <name>A0A3R7PXY6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative zinc finger matrin-type protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_019143</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003510">
        <property type="protein sequence ID" value="ROT62987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXY6"/>
    <dbReference type="STRING" id="6689.A0A3R7PXY6"/>
    <dbReference type="OrthoDB" id="30343at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000282">
        <property type="entry name" value="Zinc finger, matrin-type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040107">
        <property type="entry name" value="Snu23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986:SF1">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="8">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="136"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT62987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="203" mass="23763" checksum="BC7FD9267A9A87A8" modified="2019-04-10" version="1">MSGSGSSSGPEFRRKWDRDEYESIAQQRIRAERDAAQAQKQKIAPVKRELLKQREYKVDIDSKLGKSQVITKTTPASQSGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERSSLDQVKKRFDMNKKKLEEKKKDYDVEQRMQELKEEEEKLKEYRREKRKERKRKADSSIDEDQGSSMDPEMAKIMGFSSFSSFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2A8</accession>
    <name>A0A3R7Q2A8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000587">
        <property type="protein sequence ID" value="ROT84156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2A8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="757" mass="83258" checksum="8E3248E61F0C5FE1" modified="2019-04-10" version="1">MRHFQSSLAIPQSFLVLPPLLSPSHFFVLPPLLSPVILCSPALAIPVISLPPLLSPVILCSPPLLSPVISCSPPLLSPVISLFSRPCYPPVISLFSRPCYPPVISLFSRPCYPPVISLFSRPCYPSHYPPVISLFSPLVPSHFFFSRPCYPPFISLFSPCYPPVISFSPPLLSPVIRPCYPPVISLFSRLAIPSHFFVLRPCYPPVLCSPRPCYPPVISLFLAALLSPSHFLFSRPCYPQSFLCFSRPCYPPVISLFSRPCYPQSFLCSPALAIPSHFVLPLLSPSHFFVLPPLLSPVISPSHFFCSPALAIPQSFLCSPALAIPQSAIPISPCPQSFLCSPSPVISCYPQYPHFLCSPALAIPQSFLCSPALVIAIVILFSALAIPSHSLFSPPLLSPIISLFSRPFIPQSFLVLRPCYPPVISCSPALAIPSHFFLPPLLSPSHFLFSRPCYPPVISFFSRPCYPQSFLCSRPCYPPVISLFSRPCYPPVIPPPCYPPVISLFSRPCYPPVISLFSRPCYPPVISLFSRPCYPPVISSLPPCYPQSFPFSRPLPPVISFFSRPFMSIPRHFFVLPPLLSPSHHFCSPALCYPPVISFFALFVSPPFAIPQSFLCSPAFVIPSFFVLPPLLSPSHFFVLPPLLSPSHFFVSRAPALAIPQSFLCSPALAIPQSFLVLPPLLSPSHFFVLPPLLSPSHLAIPQSFLCSPALAIPQSFLCSPVLAIPHIRQLGVPSIRYQALPGKPPFEEDTFHFVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAL4</accession>
    <name>A0A3R7QAL4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative thioredoxin, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003972">
        <property type="protein sequence ID" value="ROT61838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAL4"/>
    <dbReference type="STRING" id="6689.A0A3R7QAL4"/>
    <dbReference type="OrthoDB" id="19690at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601:SF5">
        <property type="entry name" value="EG:132E8.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43601">
        <property type="entry name" value="THIOREDOXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="16"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="158" mass="18167" checksum="B8315E51AE4BD200" modified="2019-04-10" version="1">MAVLPKLFKFKPVMQTLLQGRASNRSLFRLGIATNKIREFHTNEQLCDIYEITDEQDFKKKVMRNSIPVIVNFHADWCEPCHSLKPLLEKIANENEGRLHLAEVLVDDHVDLLHAFEVEAIPAVLGIHRGIVTEKFVGLVSHKQVMEFVEKLLERTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBW8</accession>
    <name>A0A3R7QBW8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative echinoderm microtubule-associated protein-like 5 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_007475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001949">
        <property type="protein sequence ID" value="ROT74041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QBW8"/>
    <dbReference type="OrthoDB" id="6337112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000320">
        <property type="entry name" value="echinoderm microtubule-associated protein-like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055442">
        <property type="entry name" value="Beta-prop_EML-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055439">
        <property type="entry name" value="Beta-prop_EML_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005108">
        <property type="entry name" value="HELP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF33">
        <property type="entry name" value="HELP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23409">
        <property type="entry name" value="Beta-prop_EML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23414">
        <property type="entry name" value="Beta-prop_EML_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03451">
        <property type="entry name" value="HELP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="155"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="EML-like first beta-propeller" evidence="5">
        <location>
            <begin position="331"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="EML-like second beta-propeller" evidence="6">
        <location>
            <begin position="618"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="862"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="236"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="952"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="966"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1306" mass="141178" checksum="6845C00D0F7B9C5A" modified="2019-04-10" version="1">MFGPTPSFTPPSPWQAVGPGGAPADDDGDDGRAGAAPRGAVPCERPQGGAPTRSNITHNGDSWLCGASNDNFGGRVGLESGYERTKVLSGASSFITHLDWSSDSLYIQVNTGDSQRLIYNVLEEAIVDESSIPSVGWSTWTGVLGPQVAGLWHNFVGHSAHVTNVRWTNDSEYVVSVGGADHAVFLWRFRPSRKSSPRMDLVRLPSSVEDESDDDVLDTEDELEGIPELTLDLEEELAGSTRSSGRRSRRRTDDATPGVDVATDSTFAKRRAATDENEKANVAPIHALSVSHIFGYRAHECRNNAHWLKDGRVVYHVAAVGIVCDPQTLRQEHYLHHTDDILCLAVHPGGELVASGQIGNEATVHVWDAVDHRILSLLQGGHKRGVSAVDFSSDGERLASLGLDDYHTLVVWNWRKGYKLANARGHSDKVFGLRFSPSNSHRLITFGVKHVKVWNHVGGGLTHRQVSLGRKLKQETALCSAVGGGEGSEEWWVVGMSSGTVLIIRDLKVERVVKAHKAPMYAILVTNENIWTAGQGGYVCKWDREFTKCLKVFPVSDHFLAETAAVAFTSAQPGLRSLSAAPGTNSPILVATQHAELLLMDEEGQLNIIVQGHGKGEVWGLDTHPQLMEAVTVGDDNTLRRWGLEENLALGSVSLRKAARCVHFHPSAMFVALGYLDGSVALYLYPSLEKHGGAQHRSEGISEVKFSPDGRFLAVGSHECLVDLYVVDTDGDTVSKEGTGLRRVGVCRGASSWITHLTWHKDSRLIQANTGAGEQLFFEAPHGNRQLIPDATSRFLDWSTPLTCVLDETVEGIWAKSMDLTDINAIATANDLPLVVTACDDGGLVRLFRYPCRGGFKKHRQYKGHSAHVTNVRWTYDDSKIVTTGGADTAVIVWHVRKVEFTEDQNDEQKDGEESMMKLPAHAFSDLPEEEITMTDLEAAGLEATAVLTPSTGVHDSAKDSIGKKGGPKRAPRTAKGIKKHLERLRSIPTLTADDKTVFYCNECVVGKLELEGGEITSQGIGYKEHETHITTLAISKTEPVMVATAQLAVESEEGAAADTEAALIHVWRPLDGANVGVLRGGLESVVTSLSFSPSGRFLASLADASVVHIFSWMKGAHIASTELKVGMATSLMHSGEATLAALTPRAILFLDLVGNSLVTTRGQAPPDFLPDGAAFNGLGVSPSGRVYVGTSDGSVVEWTGRVATRYVSPPDDPPTLVPVRLAIAAGQGVIFTACRLESAVVVRCYTTDTPKLTFFSDSLIEAPSEDWIPTSARLGAEILILGARMKQPFIVLDLKSGKFTTIEYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHM3</accession>
    <name>A0A3R7QHM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001276">
        <property type="protein sequence ID" value="ROT79200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHM3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="41284" checksum="1EB62D7DA8CB7261" modified="2019-04-10" version="1" fragment="single">CEGPGETPLTPLLPQPDTPPPAVTSAPPPPAPVHSLPQPLPPTPPTLCHKLLPHHALLPHTPLPQPTSHAEQRNPRCGFNSAPGTVLHTVHTDIISKDISVSDTNLMITTEVHMCVNIHKSGDTQQGLSAGASGSPSNAEGDEAEKPSLATLEVSRRPAMTSKTSRDDVLKTEVTLSHTTAKDEVVQSYTSSKEIQTHINTENEVVRTCASSENKVTRTHVTSDCRTATERPPQPSKNSEKAQDKSRGQDSSTVNRQDNSACRQESASHRQDNPSNTRNNITKMLLLISTLFILLQLPSCLVRAYVMITGHESELLVRLQRIFLCLYNSHFSINFILYSKCGSKFWECLRSMVLSKLKRLVRWYRLVFFNDQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJD2</accession>
    <name>A0A3R7QJD2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002569">
        <property type="protein sequence ID" value="ROT69353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJD2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="42678" checksum="9F0EEE421FA139C8" modified="2019-04-10" version="1">MSFPPPIWASLLSLFSTRFPSPPHLVTHFSRLFTFSSASPCSSIVFLPPLSRRKSLPRASLRPPSFSLCAPCSLLCLHPSSSPLRVSRARLITLFLVHLSHTLPVHSPSFYPSSLPSSASAHPSSLPLSLSPLLLPPPCLSPSPPPPSLPLFAPQFPLSLSPFHIFLSLPPQPFPNLFHPSLSSPLLKHSLLSPPLSSPLFSFSPFNPPHFLSSPPPILSSRFHPSSLLLSSHHAYPLLSFTSSSLPRDPSHLSLLPLPYCPLPSPSPLCSPFLARSHQILTSHHPFPCSFSPLTLPCGHRPLSLSLHLALSPGASLDTYSLLSSRASSLLPLLHALPSPPPSLFLFPSSASSTLFSPTSSSPSPLSSPPSTPLETRVPKPPCSDRHLGGELSRGVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLC9</accession>
    <name>A0A3R7QLC9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_024315</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000812">
        <property type="protein sequence ID" value="ROT82522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLC9"/>
    <dbReference type="STRING" id="6689.A0A3R7QLC9"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000003">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="146" mass="16758" checksum="838D844B1F67E276" modified="2019-04-10" version="1" fragment="single">MQDRVRTESYRDAILKNAPLFKDKRVLDLGCGTSILSMFSAKAGANVTGVDMSDVIYKAMDIVKENNLEDVIKLHKGKLEDLEFEHKFDYIVSEWMGYFLLFEGMLDSVLYARDKHLAEGGLLLPNRCTMHLVGMEDERKRLFGLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QP10</accession>
    <name>A0A3R7QP10_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000300">
        <property type="protein sequence ID" value="ROT85350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QP10"/>
    <dbReference type="OrthoDB" id="189920at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="222" mass="24510" checksum="1822672D84586E95" modified="2019-04-10" version="1" fragment="single">MPWLSVSWEGEDVRRELATNLEVQGIPTFVVLGPDNAVITAEGRAELAEDPEAERFPWRPQSVEVLAERHMARLQESPCLVLFTDGETTSSSLDATCYSPWPRSTCGSTRRRGVSPLQFFVAGEVSAGRRMKCPTREDFACLEDAFSPGGHPGPRATSSSGRRRGSPPPTVHNFGTQCIATGNSHRCPLDSCKECYKQHELNANFFLRRSTMTLLLATLCVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QWV8</accession>
    <name>A0A3R7QWV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000098</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001012">
        <property type="protein sequence ID" value="ROT81145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QWV8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="40572" checksum="A8C110CD36C80BC9" modified="2019-04-10" version="1" fragment="single">MLITHSVLSTLPLSVLPCLTSLLASPFLSLSILFSTLFLSALQPPLSFHLSTHPLVLLLSFSPPFRPPLILFSISSSFFLLLPLFLHPSPPFPYPFLSSLSPSLPSLSPSSLSLSRFLSFLSVPIPLFPLPLLSLFPHASHPSPYLILPPSPSLLPLLPHPSLPLIPLLICSFLPSPFSSLSLPHPSPLSYLFPSSLSPSLPPPNPSPSLSPSSHPSPYLFISSSPLSSLSSPSLSSLSLSDPLFPLPPPPALLPLFPHPSHPSPYLFISFLSLSPLSLSPSLSSLLAIRSLFSLFPILSSLPYPSHSSPYPDLLLSSSPTLPQPSSLSFPSLLSLSLSDPLFPLPPQPFSLSLPSLSSLSLSPPSFPLPPHPPPQFPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QZH7</accession>
    <name>A0A3R7QZH7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022038</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000501">
        <property type="protein sequence ID" value="ROT84776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="64"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="70"/>
            <end position="92"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="104"/>
            <end position="124"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="189"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="219"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="294"/>
            <end position="315"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="345"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="385"/>
            <end position="406"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="418"/>
            <end position="434"/>
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    <feature type="transmembrane region" description="Helical" evidence="3">
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            <end position="473"/>
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    <feature type="transmembrane region" description="Helical" evidence="3">
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    <feature type="transmembrane region" description="Helical" evidence="3">
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    <feature type="transmembrane region" description="Helical" evidence="3">
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            <end position="600"/>
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    <feature type="transmembrane region" description="Helical" evidence="3">
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    <feature type="transmembrane region" description="Helical" evidence="3">
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    <feature type="transmembrane region" description="Helical" evidence="3">
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    <feature type="transmembrane region" description="Helical" evidence="3">
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    <feature type="transmembrane region" description="Helical" evidence="3">
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            <begin position="2864"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="2953"/>
            <end position="3040"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="2">
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            <begin position="2975"/>
            <end position="3016"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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            <dbReference type="EMBL" id="ROT84776.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3060" mass="337505" checksum="6551B50DF9841534" modified="2019-04-10" version="1">MFLDYIATPIYLLPRSSLVHFFLFLSSFFSFFFLGDFSLASSLVHFFFFSLSLSLLLVLILFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLFPSFVLIPLPPGDPFSSPSLVHFFLFLSSSFPFFLFLFLFLPGDPFSLAPPWSISSSFSLPSFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFPLLLVLIPLPPGRSLLPRLLPGPFLPLSLFFLFPSSCSYSSSSREIPSPSPPPWSISSSFSLLSFPFLFLSSSSGRSLLPRLLPSPFLPLSLFLLFPSCSYSSSSRRSLLLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLFPSSCSYSSSSRDPFSLASSLVHFPLLSSFFSLLFFSSSSRRSLLPRLLPVPFLSLSLFLLFPSSCSYSFPSREIPSPSPPPCVHFFLFLSSFFSLLLVLIPLPPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPRPSLVHFFLFLSSSFPSSCSYSSSSRGSLSLASSLVHFFLFLSFFFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPEIPSPSPPGPFLPLLSSSFPSSCSYSSSSREIPSPSPPPWSISSSFSLLLYPSSCSYSSSSRGSLLPRLLPGPFLPLSLFFLFPSSCSYSSSSRGIPSPSPPPWSISSSFSLLSFPFFLFLFLPPGRSLLPRLLPGPFLPLSLFLLSLLPVLIPLPPGRSLLPRLLPVHFFLFLSSSSFSLLPSSYSSSSREIPSPSPPPCFHFFLFLSSSLPFFLFLFPLPPGDPFSLASSLVHFFLFLSSFFPFFLFYSSSPGRSLLLASSLSISSSFSLLSFLLLFLFLFLPGDPSPSPPSLSNPLPPGRSLLPRSSLFISSSFSLPSFPSSCSYSSSSREIPSLPRLLPGPFLPLFSLPSFPSSCSYSSSSREIPSPSPPPCPFLPLSLSFFSFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLFPSSCSYSSSSREIPSPSPPPCPFLPLSLFLLSFFLFLFLFLPGDPFSSPPPWSISSSFSPSFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFSLLLVFLFLFLPGDPSPRLLPSPFLPSLSSFFSLLLVLIPLPPGRSLLPRLLPSPFLPLSLFFLFPSSCSYSSSSREIPSPSPPSLIPSPSPPRPFLLFLSSFFFPFFLFLFLFLPGDPFSLASSLFHFFLFLSSFFSLLLVLIPLPPGDPFSLASSRSISSSFSLLSFPSSCSYSSSSREIPSPRLLPGPFLPLSLFLLFPSSCSYSSSSREIPSPSPPPWSISSSFSLLLFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPFLREIPSPSPPPWSISSSFSLPSFPSSCSYSSSSREIPSPSPPPCPFLPLSLFLLSFFLFLFLFLPGDPFSLASSLSIFPLSLFLFSLLLVLIPLPPGDPFSLASSLVHFFLFLSSFFSFFLFLFLFLRDPFSLASSLSISSSFSLLLFPFFLFYSSSPREIPSPSPPPWSISSSFSLLSFPSSCSYSSSSRRSFLPRLLPGPFLPLSLFFLSLLLVLIPLLPGSLLPRLLLPFLPLSLFLLFPSSCSYSSSSREIPSPSPPPWSISSLSLFFSFPSSCSYSSSSREIPSPSLLPSPFLPLSLFLLLLLVLIPLPPGDPFSSPPPWSISSSFSLPSFPFSCFLFLFLPGDPFPRLLPVHFFLFLSSFFSLLLVLIPLPPGRSLLPRLLPVPFLPLSLFFLSPSSCSYSSSSRRSLLPRLLPVHFSSFSLPSFPSLLVLIPLPPGRSLLPRLLPGPFLLFLSSLFFLFYFLFLPGDPFSLASSLVHFFLFLSSFFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFSSLLLVLIPLPPGRSLLPRLLPVHFFLFLSSFFPFFLFLFLFLREIPSPSPPPWSISSLSLFFFPLLLVLIPLPPGRSLLPRLLPVHFFPLSLFLLFPFLLIPLPPGRSLLPRLLPGPFLPLSLSSSFLLLVLIPLPPGRSLLPRLLPGPFLLFLSLPSFPFFLFLFLFLPGDPFSSPPPWSISSSFFSSSFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLSLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLFPSSCSYSSSSGDPFSLASSLVHFFFLFLSSFFPLLLVLILFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPLPPPWSISSSFSLLLFPFFLFLFLFLPGDPFSLASSCPFLPLSLFLLFPSSCSYSSSSREIPSPSPPPWSISSSFSLPSFPFFLFLFLFLPGIPSPSPPPWSISSSFSLSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLFLLLVLIPLPPGRSLLPRLLPGPFLPLSLFFLSPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFSSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFFLFPSSCSYSSSSREIPSPSPPPWSISSSFSLLLSPSSCSYSSSSRRSLLPRLLPGPFLPLSLFLLSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFLLSPSSCSYSSSSREIPSPSPPPWSISSSFLSSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFFFSLLLVLIPLPPREIPSPSPPPCPFLPLSLFLLFPSSCSYSSSSREIPSPSPPPWSISSSFSLPSFPFFLFLFLFLPGDPFSLASSLVHFFLFLSSFFSLLLVLIPLPPGRSLLPRLLPGPFLPLSLFFLFLLLVLIPLPPGRSLLPRLLPGPFSLFLSSFSSLLLVLIPLLPGDPFSLASSPSPPEDFHLIPPPPLCFPIPQGEALQTSFLTTQHVHSIEPFSHIHNPEQLALRPLEHPRSQPDNQPPSQPNQPTSKPNKPPNPGINPPPMQPTHRPTQPPTEPPPQPPCNQPTVQPPRPQTHRPPTATHEPTHRRAATESAIQAPCLPGCLLLTGSSSVYRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SK51</accession>
    <name>A0A3R7SK51_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Spermine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017651</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003255">
        <property type="protein sequence ID" value="ROT64417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SK51"/>
    <dbReference type="STRING" id="6689.A0A3R7SK51"/>
    <dbReference type="OrthoDB" id="5953636at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016768">
        <property type="term" value="F:spermine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006597">
        <property type="term" value="P:spermine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015576">
        <property type="entry name" value="Spermine_synthase_animal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46315:SF1">
        <property type="entry name" value="SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="64"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="150" mass="16702" checksum="658D5A8061F6B49E" modified="2019-04-10" version="1">MTLSVKLYSNGLVTATVEYYTDQVNEHKIANDHGRALEKQLMAKFDCSVAKVLPAIKRAPPVNPYFTSSDDRLLEYDTDGIVFEEQSKFQKVQIYSTKSFGNLLVLDDLQNLAEQDLPYTHGLMNKDKEDFAGKEILILGGGDGPFCGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SP99</accession>
    <name>A0A3R7SP99_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002588">
        <property type="protein sequence ID" value="ROT69278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SP99"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="476" mass="52247" checksum="08B90BB5BDF707B3" modified="2019-04-10" version="1">MNGLMNTHTTHNTPHPHTHTHTHTHTHNISHIYTHTHTYTHSNTLPPHTHTRHNLLPTPHPPTHPHNPPTPPTHPPAPPHTHTLPLPHTYNPPITQPPLPPHATPHNLLPLHTTHRHNPSSPHHPTQPDTTSPSSLSPHTQNTPDTNLLLSAPPPQHTTPSPLIPPTHKTIPPTHQHNPPPPTHTPPFSTHTQPPPSHTHKHPPLPHTHPTQTPSPPTHTPDTTPNTYTHTDTHTRTTSSPPHTPQRHAHPTQPPPPHTTLTDHAHPTQPPPPPHTHTDSCTPDTTSSPPHTHTDTHTDTTSPPPQHTHGQRTPDTTSSPPPHTHTDTHTRHNLLPPPHTHSRTRTPDTTSSPPPHTRTRTPDTTPSLSPTHTDTHTRHNLPPPSTHTRTRMSPRDIRRSKNTSYICFLNFGIASACIPSANSAKLLTLILIAGGGNTVPEEQGESLASAADAANTTTRDRNRTRRGSEKLTRADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUP0</accession>
    <name>A0A3R7SUP0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="7">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005496</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01001710">
        <property type="protein sequence ID" value="ROT75939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SUP0"/>
    <dbReference type="STRING" id="6689.A0A3R7SUP0"/>
    <dbReference type="OrthoDB" id="10256198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000013">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050642">
        <property type="entry name" value="PDH_E1_Alpha_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF60">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="8">
        <location>
            <begin position="70"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="44218" checksum="9EB25D24756DE728" modified="2019-04-10" version="1">MLSKFIRSVVQQGHANQRALAPFMTSSVRNSGTATEATFETRPYKLHKLETPPNSTTSCTRDEALTFYTQMQMIRRMESAASNLYKEKAIRGFCHLYSGQEAICVGIKGALRAQDSVITAYRDHGWAYVMGCSVTSIMAELTGRTQGMARGKGGSMHMYAKNFYGGNGIVGAQVPVGAGIALANKYLENNGINVSLYGDGAANQGQLFEAYNIAKLMNLPAVFICENNGYGMGTSVDRASASTNYYTRGDYVPGIWIDGMDVLSVKEAISYCVEHCTSGKGPLVLEVATYRYHGHSMSDPGTSYRTRDEIQEVRQTRDPIMLFKERILSADLVTAEELKKIDGEVRKEVDEAVKIAKTDKEIAVQELAADVYSNPLEITIRGTTPYDPYTHQRLSKIINQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUW1</accession>
    <name>A0A3R7SUW1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001683">
        <property type="protein sequence ID" value="ROT76220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SUW1"/>
    <dbReference type="OrthoDB" id="10555180at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="292" mass="32479" checksum="D60ED9673B7D3FA2" modified="2019-04-10" version="1" fragment="single">EGPCLDELYVEGCPTYVFRVVRLAVMNTTRNVFIEPKGSSVITFRGERFHESVRISTRRQIRLWKNGSESCMDVSGLQPMKWRSSKNYLEIQSSKPLWFSFDCINASHSCRFHRLIKVVFVPGENGLVTWRPEGQAFKLEAGIRAYGRVDYIEPGKRSYDIAIHGSSAGPLCGISCPSLNLNFMSAAYCGHPMVIISVNKTRFLHGVTSTSLPWSLRHTASGPPEDVPTALASPSSISTVDGDKTSKTFPLLVCAREGMLRRPAKVSLVLNVTWVAGKTQLRCVDGQGYLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SB36</accession>
    <name>A0A423SB36_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020824</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004195">
        <property type="protein sequence ID" value="ROT61396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SB36"/>
    <dbReference type="STRING" id="6689.A0A423SB36"/>
    <dbReference type="OrthoDB" id="10063916at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045664">
        <property type="term" value="P:regulation of neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040373">
        <property type="entry name" value="CASZ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12451">
        <property type="entry name" value="TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12451:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN CASTOR HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="624"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="517"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="407"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="756" mass="80860" checksum="572D3768FAAB0AEA" modified="2019-05-08" version="1">MRALDDIANFDHPATLGGPLGAALGGPQPVLLPLRGPLLANPLQPQAEVVDGFYPWAEGVACPDQLCPLLGRRHYHCAHPRCLYVTAHTDVLPLHAHDFHENTPIPEGFIAIDRNIDCRSPNCQRPSSLTREAPAEDEGVAVAGGATHHSLGPQSPIYLKKPRPDSPMDTPTPGGPAGRDSPSKGQDLSPPVVKSSGIFYPLSPFPTANPGGIRPPNAARGEPGALVTPIPPSTRPQMSTTFTLPVSGSLTITATRRSPGPQAPHSPARDRMDQGDVDDRAHDFEADAARSLGVLGGDPYSARLLQQMTAEQAPLAAALGADWMNPERHPQYGPDFSCGRPFCKLKKKEHYHCQVCNQAFSEHEKLRPHLLKHAACGPMTPGGMAAAGDEDSPAQVKEEAEDAGQAPSEGGERPSSPRSPSESTSSSMGATPLAAPASSPRSLSSSSISGSISGPQFPLVYTQAASFPGLPTPFGPHLGMAGMFPGTIPRLLPPAAWQVHPALAAMAHQGLMLPGVRPNGEMPHGSPGPGGMPGVSPGLPPGLQASGDHNPVLPATLGPSPHLALLGKRLGADDFAAQDAKKIRSNHSMRLLKDEPVPEGYVRFRFNEDCQYPHCGYREHQTHFHCMRKDCGYSFCDKTRFVQHTARHERLDTLMGGDFNQFRSNVPCGRPDCVYASMIGQQQNKASHFHCLKCDFVCTDTNKVVAHRRQHQKRDSINAAGFEKFTPSQPNTSRGHVLVPAAETERVVRRSGARVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SC72</accession>
    <name>A0A423SC72_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_020382</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003985">
        <property type="protein sequence ID" value="ROT61807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SC72"/>
    <dbReference type="STRING" id="6689.A0A423SC72"/>
    <dbReference type="OrthoDB" id="6378979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="8">
        <location>
            <begin position="354"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT61807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="554" mass="63278" checksum="A3EA33DA5C3E929E" modified="2019-05-08" version="1">MPFGLRNAAQTFQRFIIFSRLQEAGVVINPGKCLFGAALLSFLGHTVTPQGITPTQEKVTAIKKFPKPAMEKQLRKFLGMFNFYRRFVPKCAQLLKPLHALITPNRASRNTKIKWTPPTNEAFEACKTLLNCPSPLSIATLSPRQSRFSAFGKELLAAYSAVRHFQPYLEAKEFHILTDHKPHTFALHSRTRRQSPREERHLDYISQFTTDIRHIRGADNKAADALSRVTIAAATHADDAVDYQLVSSEQCQDASMTPLIEGQTSLSLERVKIPNSCNDLLCDVSLKYPRPYIPPSLRRRFFDAYHQHRGIRATQHVIRGKVVWSGINKDVREWCPSCIECQRTKIYRHTKSPFQTFPIPDERFQHIHIDIVGPLPSDDGYSYILTMIDRFTRWPEATPIRDITAATVARTFLSTWISRFGTPDTVTTDRGAQFESELWRQLMVLLGSKRIRTTAYYPSANGMVERLHRHMKQALTSSSSNRRWVDQLPHVLLNIRTSFKEDLQCTAAEMVYGTTLALPADFIVTAGNFEPGTYGKQLCERMTRVRSRPTRPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SC87</accession>
    <name>A0A423SC87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arrestin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003982">
        <property type="protein sequence ID" value="ROT61819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SC87"/>
    <dbReference type="STRING" id="6689.A0A423SC87"/>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016060">
        <property type="term" value="P:negative regulation of phospholipase C-activating phototransduction signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045494">
        <property type="term" value="P:photoreceptor cell maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007608">
        <property type="term" value="P:sensory perception of smell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.840:FF:000002">
        <property type="entry name" value="Arrestin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017864">
        <property type="entry name" value="Arrestin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF23">
        <property type="entry name" value="PHOSRESTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00309">
        <property type="entry name" value="ARRESTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00295">
        <property type="entry name" value="ARRESTINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="279"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="50830" checksum="1AB681CF2924863F" modified="2019-05-08" version="1">MNGVNPLGRKGKPDLEGDRVFGAVTPQPPPLPQMTPLLHGLNISLASVWLKSLQNEVSPLTTNPITPAWPYKNRPPTLLGISFSPTVFGTSHSSESTNNHFNGKVTAYLSRRDFVDHVSHTSPVDGVVVVDHDYLRGRRVFARVAVTYRYGREEDEVMGLHFSKELELVNTEVAPHAGDVQMTDAQERLIKKLGANAYPISVNLPENAPCSVSLDGGSEGSTQPLGVIYDLRLYVADRKEERPHKRNSVGFAVRKVQYACPGSSNRQPQTLVSKGFTLSPGRLNLEVTLPQDVYFHGQPIEATLSVNNVSKKTVKNMKAEVVQHVEVTMTNTHFSRVVASLESREGCPITPGCNLTKTFSLNPVASVNKRRFGIALDGQVKDQDANLASSTLVAEGKNVNDALGIIVSYSVRVKLNCGAIAGDLTADLPSSWCTPTLPPSRLHCARLSLPISKWRNSLTCAWSVHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCP1</accession>
    <name>A0A423SCP1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 70 kDa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020143</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003863">
        <property type="protein sequence ID" value="ROT62018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCP1"/>
    <dbReference type="STRING" id="6689.A0A423SCP1"/>
    <dbReference type="OrthoDB" id="6351471at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000135">
        <property type="entry name" value="Heat shock cognate 71 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="580"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="601" mass="66022" checksum="90E21973AF35BA0E" modified="2019-05-08" version="1">MAAPAIGIDLGTTYSCVGVFEHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTVFDAKRLIGRKFEDATVQSDMKHWPFAVINEGGKPKLRVEFKGESKSFNPEEISSMVLTKMKETAEAYMGKAVKDAVITVPAYFNDSQRQATKDAGTIAGINKSVGQGERNVLIFDLGGGTFDVSILSIDDGVFEVKATAGDTHLGGEDFDNRMVTYFVQEFQRKFKKDLSSNKRSLRRLRTACERAKRTLSSSTQASLEIDSVFEELCSDLFRGTLEPVEKALRDAKLDKTSIHEIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILRGDQSDTVKDMLLLDVTPLSMGLETAGGVMTVLIKRNTTIPTKHSQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFDLSGIPPAPRGVPQIEVTFDVDANGILNVTAVDKSTGKENKITISNDKGRLSKEEIERMVNEAQSYREEDAKQRDRIEAKNRLESLCFSIKSSVNEAGVCGKVSPDEKRCVEGKAEETLRWLDANQLAEKEEYEYKMKEMEEVWRPIASKLHGSGGCPGYGASTGNGPTVEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ65</accession>
    <name>A0A423SJ65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BolA-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017857</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003295">
        <property type="protein sequence ID" value="ROT64232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ65"/>
    <dbReference type="STRING" id="6689.A0A423SJ65"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990229">
        <property type="term" value="C:iron-sulfur cluster assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.90:FF:000001">
        <property type="entry name" value="Transcriptional regulator BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050961">
        <property type="entry name" value="BolA/IbaG_stress_morph_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46229">
        <property type="entry name" value="BOLA TRANSCRIPTION REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46229:SF2">
        <property type="entry name" value="BOLA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="11785" checksum="B89B3C04912302E8" modified="2019-05-08" version="1">MSSNGAVESAIKKKLVEAFQPVHLQIVNESFMHNVPPGSETHFKVLVVSPTFENVPLIKRHRLVNAALSEELASGVHALSIVARTPDQWEKGSQEVERSPACRGGFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLS9</accession>
    <name>A0A423SLS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003133">
        <property type="protein sequence ID" value="ROT65150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLS9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="504" mass="52473" checksum="B9023D93B0F15B42" modified="2019-05-08" version="1">MDPRDSSVSFGGDKKWTSIKDLNSLSTITNDDGGKGLEGRSDITPPPHAAAPHSSSSLLPSFTSSLSEPYSSHPPPSHSPRRPSSSLLSSPPSPLPSPNRIRSLHAHSLGALNSPLLSSLLHTLPSPKPCSCTAPPTLARRRLILTLLSCPSSPLPLASRIRSSRPPSTHHRSPHSISLLPFTLPSPEPVFLTPPPTPTAPLTPHTSAHSPSTSSPSPSRISGAGRLPPSNSLAPLPHTPFPLPSAPSHTPPAPRPSSSSPCHPLGASATRSHSCLGAPAPDPLPSPRRRLPDSPRRPCPTNIPSHSPGAPAFPTQDTPSAHSLLGGPPPSSPPPPPPSPSHPQTLPRVTIRPSCHSLHSWRPSSLPRPPHTTSAPPAVPPPSPHPLSAPPPPLHPPPAAPSPHHPSAPLSLPPHPTPTTPLFAAPNTLPKNPSSLLRLKSRLPTSLPTAPCPPSSLLPPHRPCRPSSPHPGTLPATPSPPSLAITRLPLFRALRLWAICSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SP31</accession>
    <name>A0A423SP31_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_016068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003014">
        <property type="protein sequence ID" value="ROT65941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SP31"/>
    <dbReference type="OrthoDB" id="6375279at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21407">
        <property type="entry name" value="RE43931P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT65941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="146" mass="16429" checksum="31ADE87D686C4BBD" modified="2019-05-08" version="1">MNGVHYRAHHTTLGETGVPYIKRKFTVATPADISSTPSDEMKALLFLCVVAAATSQHYGLVDLRYGGSEYHFSWRHDGGRKYQWGPANSYCSSLGNGYPQPTTARDGREFCLAVLNNFYNDGIRWHDVACHHEKPIVCERRVGFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQP0</accession>
    <name>A0A423SQP0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002919">
        <property type="protein sequence ID" value="ROT66537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQP0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="202" mass="21855" checksum="A18070BC84E2FF7D" modified="2019-05-08" version="1">MVDSEGAQIGRTDHSVEYDAQLAPFKSEGSSRDSISGHTGSAEYSDPQFEHLNTSGLQTSEMNPGPSEMIEWQDGIVQSDMTSGEGCSGVGILQPSSPMLSQQTPQLLAQQGMVALEGSAAAAAMVRVRGGYTRWTPEERLLIAKACIRMGPNKAARELSRTLNKKLSKSTVQNIHKQYLERLAKRQLVNAPLSLPQGRQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUB2</accession>
    <name>A0A423SUB2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Unconventional myosin-XV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_014123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002759">
        <property type="protein sequence ID" value="ROT67780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUB2"/>
    <dbReference type="STRING" id="6689.A0A423SUB2"/>
    <dbReference type="OrthoDB" id="6349769at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13201">
        <property type="entry name" value="FERM_C_MyoXV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002404">
        <property type="entry name" value="IRS_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041795">
        <property type="entry name" value="MyoXV_FERM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051567">
        <property type="entry name" value="Unconventional_Myosin_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692">
        <property type="entry name" value="MYOSIN VII, XV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22692:SF26">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02174">
        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00139">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51016">
        <property type="entry name" value="MYTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="313"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="MyTH4" evidence="9">
        <location>
            <begin position="472"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="148"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT67780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="943" mass="106627" checksum="70BFC8C3A29513E5" modified="2019-05-08" version="1">MSRMHPDPDYSDLEHDSLDIVQDSLEPCYAFPKDDLLYDSLQPVPTGRGLFGGLDAGFPLGAKIRFNPLSFHMPGIGDDDQDYEEMLHDHRAFDADPREAEGDADAEQKYSCSSEYIVAGGEALRASRDDLRDERPTTPVLSLHGRGGRKERDGEAVKDELADSDFDSFERKRSETESASTDSFYDTPEGDVYDPSLPYIPPALQLKTALKTGFKASRLSVNFEDDIYDPSLPPIPLLDAPPAPALKSALKGSVSSRRSAGSDLSEITSVSPALDDWHEALGATARMGWAILLYHAVRNNFKPRAFAHLAFQGSREFVRAIADYMTTGSTLLNFKKGDIIRIITTDQFGDNGWLQGTLDGRSGLFPMEYVVPIGRSEARNAAKERVNHVKTEDIDPGLIENESEVRSAPVVHDGKHSLLQFALQHFRMSKEQGIVQSDGTLQASNNKNKKKKTSKDQVAEWTWKEQVEMVKFSQSPLTASLLPLVPELDNLAIETFVAVMRYMGDYPMAPQQTEVHCVYTILMNCHKHHALRDEVYCQIMKQTTNNKSSIPDSCQRGWRLFSIVAAYFTCSENLKPYLFKYLETAAYDKRRAYHGTSMVCLQNLRKTFKYGGRKNVPSIEEITAITAGRNSKRQIYRLPGGTERVINTKSTSVVQDIIEEMCSLIGVRNPHEQEEYSLYCIVEGDTFTMPLAREEYILDVTTELLKNQQVFYLIFCRSVWYYPLRSDNALYYEVVFNQIAPDYLEGLLLVTPGEQLQQDVIYDIAKVAALLHRAADLEDVPTMKEVKYLLPKPALTVRDVKPPQWVNMVQSAWPEVSALTKILQSWPLFGSSFFAVKRVTEPKERSDHILALNKNGVHFLDLLTHETLIKYSLAEVMSTRKVKSEDELYLDMKCGNLMQQRITRIQTEQAHEISRLIRQYITIEQRTTGHSRGDNPKDVTLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1M2</accession>
    <name>A0A423T1M2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011336</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002435">
        <property type="protein sequence ID" value="ROT70377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1M2"/>
    <dbReference type="STRING" id="6689.A0A423T1M2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019025772" description="Apple domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="751" mass="80452" checksum="E5E589A683A03CEC" modified="2019-05-08" version="1">MTVFGFVVVFFVALTLASQQITWLRAGSDVKFVRSGTVLEVKSVARIQCGVACCILEDCLAFNYHGPTSECQLLSAAPASLAAPDVVASPDWAFYVVNVPSWVSPDAGHGLSQRGVRCGNIAGKSSWEQNRDPCSASGCPVTTMCLGYDQPVQLIPYNSSLPEFICSDNVYYLRRRKAGLAGCRLEVIYGFDLYGFDTAYLGVSAPYHEALQECMTYNCVSMACHGTEDGLRQGLFEGQGRRANVQSECGHRHERFGCVTFSSRLMMVLSQRPTLSARNPTNAPLISPLPSFSPPSCSYSALPSASPFCPSNRSTPRPSHILLPAFALPSRPPPQPHRLLLISPARGLPPFCLHALTPPLSNYPSHPTPPPLRPIPYRPPFSYPCLPIPLVALCPHPYRACASSQYPLPFPLPFSLTPKPSASSHMPLPSPSPPPFSPARPPTPPPLISLSPYPPLSPPLLISLSPSPRPTPTPCLPLISLSLPSPFFLHPPPASSSYHPPLPYPSPFSSTPTPAPSHIPLPYPSTPPTRIGAAELGVVGFRRSSVAADTGQRQAFAVRRQVLCLPRDIYAGVRTPKIASESESQGSRSYITGKCQLPEPFGVPRSFSVEMEAARRIFDGAENVYFWHLGVHPADRHPHPPAPCNGAERHLTPAATPSLLACWSRLQRARVSCLAGAAGGAEAPLGGTGRGGGRRQRGLAGALGGCAGVVLVGVQVGGHGGCEPRHHAPRGRVWAWARQVRGRASCYSAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1N1</accession>
    <name>A0A423T1N1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Activator 1 large subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Replication factor C 140 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_011448</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Can bind single- or double-stranded DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Large subunit of the RFC complex, an heteropentameric complex consisting of RFC1 and four small subunits RFC2, RFC3, RFC4 and RFC5; the RFC complex interacts with PCNA and the interaction involves RFC1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002445">
        <property type="protein sequence ID" value="ROT70293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1N1"/>
    <dbReference type="STRING" id="6689.A0A423T1N1"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000021">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000005">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor RFC1 C-terminal" evidence="8">
        <location>
            <begin position="130"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00064311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00075134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00077727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT70293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="290" mass="32984" checksum="B72ADEF11BE1EFF0" modified="2019-05-08" version="1">MSICFREGIQIKPDALDQIIIGSNQDIRQVLHHLSMWSANEKNLQVNDMKREAEKAKKDLKMGPWDVCKKVFSEADHKTMSLYDKSDLFFHDYSIAPLFVQENYPKAVPHIAKGNRRVTLEQLAKTAGSLADGDLVEKAIRSKNAWSLLPTQAMFSSVLPGEYMSGHLAGQIEFPRWLGNNSRRNKFDRIMQELQMHMRLKISGSKLDVGMDYCGHLRNAVINPLIHHGQDGVQDAVKAMTTYDLLREDLESLLELSQWPGSKDPMSRVDSKVKAAFTRLYNKESQPIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1X4</accession>
    <name>A0A423T1X4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative kinesin-like protein KIF13A isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_011213</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002418">
        <property type="protein sequence ID" value="ROT70484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423T1X4"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22706">
        <property type="entry name" value="FHA_KIF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000167">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022164">
        <property type="entry name" value="Kinesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022140">
        <property type="entry name" value="Kinesin-like_KIF1-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032405">
        <property type="entry name" value="Kinesin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12473">
        <property type="entry name" value="DUF3694"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12423">
        <property type="entry name" value="KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16183">
        <property type="entry name" value="Kinesin_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="295"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="525"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT70484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1422" mass="159352" checksum="7B95FDB599F43E24" modified="2019-05-08" version="1">MNAISLPTRGATDPEVLGRGSDVVSFLAAGSGKSYTMMGTADNKGLIPRLCDTLFERIAASAQQSTSHKVEVSYMEIYNEKVHDLLDPKGSRQTLKVREHNILGPYVDGLSLLAVSSYEEIEQLIEEGNKARTVAATNMNSESSRSHAVFTVVLTQTMTDVASGVSGEKVSKMSLVDLAGSERAVKTGAVGERLKEGSNINKSLTTLGLVISKLADSAVGRGKSKGDNFIPYRDSVLTWLLKDNLGGNSRTVMVATVSPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKIIRELREEVETLRTQLQSLRQVTRDGHASLQEEESLNEKLHESEKLITNLSETWEDKLKKTERVQQERQQALEKMGISVQASGISVEKNKYYLVNLNADPSLNEMLVYYLKDRTLVGRPDAGSTPNDIQLSGVGIETHHSVLVIENSDLFLEPYPNARTCVNGSQVTEKLQLRHGDRILWGFNYFFRVNCPKTSTGGNNSEPQTPAQPIDYNFAREELMLKELSNDPIQAAIQNLERQHEEDKQMALEKQRQEYEKQFQQLRNILSPTTPYAPYMPFDPLRGTKMTPSTPTSQLRIEKWAQEREDMFKRSLAQLRQDIMKANTLVREANFFADEMGKQTTFGVTLQIPPQNLSPNRKRSAFVSEPAILVKRKGKPNQVWSMEKLEHKLIVMREMYDEKQNDPLVSRPEADPFYESQENHNLIGVANIFLDCLFHDVRLNYHIPIISQQGEVAGRLQVEISRISGQFPQERFADTLSESSGDSAQSREDEEIQNNTVTVRVCIKQAAGLPPSLSHFVFCQYQFWGQTESEVVAPVVNNEFPAAPTSKDSMTFKFEHSKDYTVMVTEDLLEHCADGALSIEVWGHRSAGFGISRPGWEVDQQLAKARSLVDRWNELTRKIEMWVEIQELGECGDYVSVEVLPQKDVLTGGVYQLRQGQQRRVVCRVKPVSNSGTLPLICEAITSINIGSVCGRLRCQRQLDSYTEEDLNILRERWSEALKRRRMYLDQQIQKIINKGDKNEHDVEREQSLVDQWVTLTEERNAVLVPAAGSNIPGAPADWDPPSGMEAHVPVLFLDLNADDFSTQGFGDTMTIAGTNAIIPKENCNKFFQLPIIKCYEKDVCAVASWDSSIHDNQYLNRLTPNDERVYLIVKAVVRLSHPAPMDMVLRKRLAVNIYKKQSLTSKFVKSFIGSTNTLYETGIMYEVVSNIPKASEELEERESLAQMAANADDSHAEDGETYIEKYTKGVTSVESILMLDRLRQNVAVKELLQSAGRPLMRKTASVPNFSHLFGSLDGGLDGVTRSGSVMDLNAQLSSAPTPNHADKNKHRYSLPGPSERPFGLSRPTFLNLNLNLNSLRLQGSTPAKFTHSLNLLITYSLSLMYSIYLSLAHPPQSLPYPSLAMLLSTSLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T268</accession>
    <name>A0A423T268_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011356</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002438">
        <property type="protein sequence ID" value="ROT70348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T268"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="47802" checksum="BD1BCC46A60AADA6" modified="2019-05-08" version="1">MDQAMDLAVALACGFGCGSGSCFAPDDGHVERWLSLSSLYHRVLLSVLSSLSLSGSESVSSLVALVVSSLSLVPARAHVSPPTCLSTSSVRRRPLSLSRPRRSSRPPSSPPEAPAAPDPPSAASSRLHSLSPLRLLLLPPLSRGLQSLVPVMLLSGFSACRVSSSVSSVSPSLSPPSLISLAWPFSSRALFALSALVSVARLSTISPLFSCSLVSRLSSSLSCRPCGGVSLPSYLSTSPRLPPPLISLSVSLSSLCFCSPRLSLVIFLHRPLFLCLVALPPVVPRCVLARSSPLVPPLPSLLPSLVSRWLSSALSCVLLSASLIIVIYSLFASSPSRLSNSPLSPLPLPPPLPPLPESPPSPALPSRPLHLSSPRLDRSVPHFPPSLRSPLIVSHVSISSLLLPHSLTFLLPPRPAGVPSLRSPSLLPSLPVFPLAWSSVPAPLSSPSPSPSTERVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5K4</accession>
    <name>A0A423T5K4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002247">
        <property type="protein sequence ID" value="ROT71789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5K4"/>
    <dbReference type="STRING" id="6689.A0A423T5K4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="40902" checksum="574CE2122C13FBBD" modified="2019-05-08" version="1">MWNRYTEHSKSTPPPIRPARPSKHPPPHPLSTTTNPTRPSHTQAPTTIAHHPLTTTPSATFPPAPTPHPPHPPSPTTIRHLPTSTPPPIRPSTLSPPTPSATFPPAPTTPSAHPSTSSQHTTHPPIHPLTTSHPPTPPPISTLSTYLIHPITLSCPHHPSAPPLSSTIHPAHTHRPSAHRAIPPPIHLLPTLPTHQSAPPPFTPHGTVHLPPPRADGRLQAHRHHQTRPRSPRPPRPLPTAPSPLRPRQQGNTLNNIQGGLNTTYGEDMAARGELLHLHCSLFLPSPYLTINPAYRSCPPPYSPTPTRSSSPVIHFLLHSSFLPLSFSPSPQTSFNSSFPSSSFFTSSFSHPPLPHPHPTKLPSPLPSFPLFFPLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5V5</accession>
    <name>A0A423T5V5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002234">
        <property type="protein sequence ID" value="ROT71892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5V5"/>
    <dbReference type="OrthoDB" id="6364341at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019335764" evidence="1">
        <location>
            <begin position="19"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="16218" checksum="B7581D9E0F38E931" modified="2019-05-08" version="1">MKVLFSLFSLVALSTALGQREDVWCRCALMVDSDPMLYMVYDLGEAFIEACNTGRKHCFLSLQIRAATNEMDLWSHDDSGFTIGSNICQYLFSSYNVDQFNNKYVHGYYQVCGGPWEYTFQDSQQMLCCNMGIHEHCITRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T691</accession>
    <name>A0A423T691_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative guanylate cyclase 32E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_009637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT72017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T691"/>
    <dbReference type="STRING" id="6689.A0A423T691"/>
    <dbReference type="OrthoDB" id="1890790at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="254"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="308"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT72017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="39667" checksum="91CE2ABB735CE504" modified="2019-05-08" version="1">MPRYCLFGDTVNTASRMESSGQALRIHCSCSCRDLLVKLGGYNLEERGQVKVKGKGEMTTYWLVGEDPDRKRRREQSRRQRGFHNVGLAKNGCVGGLRGSLRGGGRTRSSAIPRTLSLESPKRLRFAMSEELTARVAVEEPRAHEMKRNSCPCIKEHRSAPRASSPRSPRGPPGDHSPLLGHPEAAMSPLSSPGVSADEEVLNASRRTSVSEVVSRPSSLVEASDEHAPPAPGEPPPPLALAALPLSAAISLEHRAPASPLRDAGTAVASPSTPGGSKPSSGAGGGPPDKASSSGSAVRWRPHSIVPLSLRSGGESEALLSGGGVEGRNPRLRYCSKQDAGSSECEESSPLLASVVNYRVINEVHKLPERETPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8I6</accession>
    <name>A0A423T8I6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8I6"/>
    <dbReference type="OrthoDB" id="6389475at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="224" mass="23423" checksum="E86B543FB59A808A" modified="2019-05-08" version="1">MDPETETGREKEGKSATRASAPTTNQLFFASPALSGNSPCCTSSASRLCCLSLSRRTWSSRGSVMRASLLLVFALAALVAAAEAKKCKGECVSAGSCEGTEAKGKCDDSQVCCVTEGNVDVKGKCHATSECDDLLGECRAKSCHPGEVTFKNKGTNVYCEGKKCVCCAKTCENKKSCNLKGGVCQPISQHCDGTLETGKPYCKASPKMKAGNKNTCGCCIPPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9T1</accession>
    <name>A0A423T9T1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pyridoxal kinase</fullName>
            <ecNumber evidence="5">2.7.1.35</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pyridoxine kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_008383</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>pyridoxal + ATP = pyridoxal 5'-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17310"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="2.7.1.35"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:10225"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>pyridoxamine + ATP = pyridoxamine 5'-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57761"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.35"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:25105"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25108"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16709"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.35"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:25109"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxal: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxamine 5'-phosphate from pyridoxamine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxine 5'-phosphate from pyridoxine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002056">
        <property type="protein sequence ID" value="ROT73187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9T1"/>
    <dbReference type="STRING" id="6689.A0A423T9T1"/>
    <dbReference type="OrthoDB" id="2104723at2759"/>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00298"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="15">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT73187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="187" mass="20702" checksum="EE1E5E53E302E160" modified="2019-05-08" version="1">MGDHGKMYVPEDLLPVYREHIVPLADIITPNQYEAELLSGRKIKNEGDALEVMKWFHDQGAKTVVLSSTELGSENELLGLASSVINGTSTRLQIGIPRLPVNFTGTGDLFASLLLGWMHHTDSNLKKSVENTVDTMQTILRRTLDMARQEAGPDTPLTVRHLELKLVQSLDDIRSPVSKCKASVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TD08</accession>
    <name>A0A423TD08_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001916">
        <property type="protein sequence ID" value="ROT74267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TD08"/>
    <dbReference type="STRING" id="6689.A0A423TD08"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="512" mass="55101" checksum="51C3059E3861AA1E" modified="2019-05-08" version="1">MILPAPLLTTTPHSATTPHSAPRPHSATPHSHPHSTTHPPLAHPPPPPISPPPITSISHPPHPSPFHQPPTPPISPPRPYPHPPSSTPTPYQPTPSHPTPTPPTPQPHLPPSATPPHPTRPPHPPSATTYNPISHPPPRSQATRTHPPPHPPHQPTPTPPSATHTPHPATPTPPPPPPLPPIQPHHPPISYPTVHPHPTPPPISHTHPPIQPPHTPISPPQKPTPHPLTPTHPSAHTHPHQPIPHPPSASPYSHPTPPTHPAHTDPPSAGIPTPPISHPPHPTSTPPPTYQPHHPHQPPTSPFIHPYPTPPTLFSHHPPPISTSHLPISTPPHPNPPMQNHRSTRHQPPTHPHQPPHPTPISHSIPRPYQPPTPTPSCHPPHPIKRPPPTHQLTPNPHQPPPLPNSSHPPPHQPPPPPSGQPPPTPHPSHHHPPSAPPTHPFQHTPPPIQATPQPTTHHHPHPHQANPSHPTPTPPSPFSATLNSDGNETPLHLLPHRGTTHHLTATNNLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TD74</accession>
    <name>A0A423TD74_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001899">
        <property type="protein sequence ID" value="ROT74430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TD74"/>
    <dbReference type="STRING" id="6689.A0A423TD74"/>
    <dbReference type="OrthoDB" id="6341525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="218" mass="24956" checksum="F3C10FDFA89401D5" modified="2019-05-08" version="1">MRPEWLKEGNRRARRAKEGQGVLKRVMEMFTAPTSAVYLDEEPTKTKKISDTSNPDFNHAKLYSFTPATRQVTWVFLIVVYLIDRWVDCSRMNCLVISVMGKQRVRKSAMPRTNGLTTKEMLRSDRAVFAKTANLMNGFQMNGRVVDPQKQSIIVELLLMKKTQARLQQKVDSVRKLVKEAENISKVRVSTSLLKEVLQANTPEQADMIIRKITGPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF13</accession>
    <name>A0A423TF13_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001816">
        <property type="protein sequence ID" value="ROT75042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="879"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="556"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="682"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="855"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1287" mass="137184" checksum="C3EB6AEFDC2CB3FC" modified="2019-05-08" version="1">MLKKKSSRRSQIPPRNDGIEKQARSRAFSPHSILSSPKHPLPTASSSPSQPISPPQPCILSSHSILSAQHPSAPQASLPPQHPLPHSILSPHSILSPTASSPPQHPCLSHSILSPHSILVPHSNPLPHSNPLSHKHPLAPQILSPTASLPTASSPPQHPLPHSISLSPTAAHSLPHSILSPHRSSPPQHPLPHSILSPHASSPTTASSPTHSISLISHQQSFLHSILSPTRILSHSILTPHSILSSHTAMRSPANIASLSPTASLSPTAHPLSHSNPLPQAILSPQASCFHSIPSPPHASWASSPTSILSPGILSSHSHLSPTASSSPQILLPPQISSVTHSMLSPTASLRPHRRGRVSTASLPPTASSPPQHPLSTSILSPQHPLVPQQSLSAHSNPLPHKQFSSPQHASLPSHPLSHSILSPQHPLPRAASSLHKHTLPHKHPLYPTSILPHKHPSLCPLATSLSSHSHPPRASHSIPLPHSIISPQHHSPHSILSPTASSLHSILSPNSNPLPTASSSPNSILSPTNLSSPQHSFSLPCSIPLPAHSNPLTPQHPSSPTASSSPKQQSSPPQHSLSHSILSSHEHPLSTAILSTHSNPLPHQHSSPPTALLSRQRSHSTPTLHPLPPQHPLAPLAFLSPHQHPRLPQHPLPHSILSNPTASFSHHSINHPQHPLLHQQSSPPRESSRPTASRGIRLPTASSSLRESPTASSPQAAILSPESILSTASHLSPQHSTSPPTAILMHSQAFTLRPQHSLSHSIPLPTAILLPPTDSRLHSNPLLHSILSPHQHPLPHNSILLSHTFSAPDSIRRPSQHPLPHSILSPHSILSPTAFSSPPQHPLPSQHPLPQQHPLPHSSLSPQHPLLSTAILSLTSNSLSHSDPLSPQQFSSAPQHPLLRAFSPPQHSLSHKHASLPTAILLSPQHPLPTGILSPTAILVHQHPSPRQQSLITPQQSLSPQHRSLTQSHTHPLLVTGSLLAHSKERHASLPTAFSPPTSIPLLISIASPKAHSILLLTQASPSRTASSPLNSHPSSLHSISSPSQILFPTETATVQWSERSILSPHSIISLNAASDPPQSSPPTAILSLTASHPSQHSRFPNSILFYFSHPKSFLSKILFPHFHPRLPPCFLLRLPSSYVLSRPLHLTSSAASPPSVSPPLPLRPPPCAILLRHPPLRLLRPASHLPLRLDSLLLRLPPSSSLRLTLPRLSLLRLPPPSPTPPQFPQLRTLAFPCMSSIHMPPLASPGFSVPSDSWVPPGPAPSPMGSSPASTHSLAAVFSSPFMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFI0</accession>
    <name>A0A423TFI0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">BNIP2 motif-containing molecule at the C-terminal region 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001803">
        <property type="protein sequence ID" value="ROT75191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFI0"/>
    <dbReference type="STRING" id="6689.A0A423TFI0"/>
    <dbReference type="OrthoDB" id="19923at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.525.10:FF:000001">
        <property type="entry name" value="BCL2/adenovirus E1B protein-interacting protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022181">
        <property type="entry name" value="Bcl2-/adenovirus-E1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF22">
        <property type="entry name" value="MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12496">
        <property type="entry name" value="BNIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="7">
        <location>
            <begin position="817"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="40"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="732"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="605"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="742"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT75191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="993" mass="109389" checksum="088D7A5FA52C8B15" modified="2019-05-08" version="1">MRGSPLEIRFSWGLDGFESVAVVMRGESGEAIVGAGVGDEGMLSRQSSGGVKSPASPPLSAAASQVSLAPSDLTTSDPDIAGSSAYSSAPSSRPPSSSQVSLAPSDLHSSDLDLTATSSPTSSRPPSSSGIATPDLTLPAPEDYTAETVEFPTSPLAMKTVGLKSNGVCLVDSEDSGTGTRSMSNFLSPDYKPDELESCENSPRQGDGFEVSSDLEEDYFEEFHLPNSHENAFVRHKSFRRKVNLTPINAPDAEKIEGLVRAGEFQRHGSMRRKIVPAETTIQEHVDNEKSALDSNENLKEAGANVTLNSEVGTFAKDLQEIENLLNDCEVGEDISDIVLDSSAGNDLRKELEESDRSTLQQGKIQHTNTSTPKTNSTRSTSTYAATDLSLSLTEESREDESLSIEQSTLMKVRECLDFTKYRDMYNLSGRLQDILTPKEVEEILNNSERYSEYVDKEVIEALHNSLQEQISSHNTRNTVDSGISSPKKTVITTEGLDLGNTVKKDIRAVFDDSSPVVHENDSNSSKRSSDIFIDDIDFDDSDDTGFRFERRRSLRLSKEGHEELEVEGVFVESKSQDLGMKKIPAPVLDLSGATSEDLNDVPDLSNSEILTPQRQPDLPGMSETRVPNGVAQNKPLEVPDIVITGTCDPIETQNESTEKLLVEGSDLSDVTTPSLVNTPSVVNTPSTTFEYMTPDEERPSVLDFGNISQRKRISVAEDILRSPVEDDNISVASAFSQRSDGEDEDGFGDEDLDIYQTPKGNLGAPSESTQHLEPIPTPPPQLLIPEFSASEESAEERHWRSVVIGGVWRRIDMKVIAPYRKCVSHGGYLGGDQNAVIVISACQLPDRSRRDYNYVMDNLFLYVLSTLEQLIADDYVLVYLAGGTPKSHMPNFHWLKRAYQMIDRKLRKNLKALHVVHPTFWVRTVVAFSRPFISTKFYRKLTFVNNLTELAQVVPLDQLEIPDAVKQADFELMIREKKKNLNKSRTPSLVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG71</accession>
    <name>A0A423TG71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphatidylinositide phosphatase SAC2 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG71"/>
    <dbReference type="STRING" id="6689.A0A423TG71"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045334">
        <property type="term" value="C:clathrin-coated endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001135">
        <property type="term" value="P:regulation of endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034753">
        <property type="entry name" value="hSac2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022158">
        <property type="entry name" value="Inositol_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12456">
        <property type="entry name" value="hSac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51791">
        <property type="entry name" value="HSAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="1">
        <location>
            <begin position="218"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="HSac2" evidence="2">
        <location>
            <begin position="702"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="791" mass="90234" checksum="9C88AEE63FF3E2A3" modified="2019-05-08" version="1">MRGEWTEWPWRIDVSNNHPCAAIVRLHVLQRAMEVLQTDKYYIFNRGQDSLWCDRRTGQFQAKTCWDLASAENPTCLGIIHLLLGKLQIHPDLSPRLVLVSGVREVGSLAEGQRVWCITRVVFLPLNSPPDADFSILPCKKHANHPSSLSGEKKLGLPFGDLQQKVALSKTFGTIRSVTSTIKSATVNAAATATGQSKVRRDGRDRDRYERRVLDELSKMFNDSDSFYFSSEADLTSSLQRQSLSSYDRSLPIWRRANDNFFWNRHLLIDLISQEGSNFDVWIVPVIQGFVQIEAVPLDAPISSPDDSVDKSRDHYTLTLISRRSRYRAGTRYKRRGVDEEGYVANYVETEQIVSYSHHRVAFVQVRGSVPVFWSQPGYKYRPPPRLDRDTAETSLAFKKHFEREVSHYDHVSCISLVEQTGKEKVIADAYLNHIFMLDSSDLTFVTFDFHEYCRGMRYENVSVLIEGIEDCISKMLYCWVDKEGTICRQSGVFRVNCIDCLDRTNVVQTAIAKSVLEGQFVKLGMIPPEHPLPPACRSTLQIMWANNGDTISKQYAGTSALKGDFTRTGERRFAGMMKDGMNSANRYYRNHFLDAYRQVAIDVMLGLELSEDQWQEINYVETLLNVASALMPIGPPSYMAEIAPGNEKYLASALYSLSRYYMNRFKDAYRQATIDHLLGNPIRDDMITFNPELAGEEEESSMTPEHVKHVIDDCKKLLVPDAETILGAWGLIDADPSTGDPDQTDMDIILVLTRDSYYVAQYDEETDQILRYERVSLIDLEKIEMGPYTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGE8</accession>
    <name>A0A423TGE8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine protease</fullName>
            <ecNumber evidence="11">3.4.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_005919</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01001760">
        <property type="protein sequence ID" value="ROT75526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGE8"/>
    <dbReference type="STRING" id="6689.A0A423TGE8"/>
    <dbReference type="OrthoDB" id="2960936at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019786">
        <property type="term" value="F:protein-phosphatidylethanolamide deconjugating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035973">
        <property type="term" value="P:aggrephagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF52">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0645">Protease</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="13">
        <location>
            <begin position="289"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT75526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="348" mass="38182" checksum="CDCD194A43C9BDAF" modified="2019-05-08" version="1">MLPSIQSVASRHGSPNRQHKRSSSSGGFFEEPVVPIPMAKECTESTESSQTRNHPSGQKPRYVAEGMNGSATNDGRKPTRVKLKKALSPNHKPSHFFVRTAGGMSVSVPELSPEVNMSVKDQINFIPSDPVPQLDGNSLSQNESPSVEGASKNETNRAQTYLPLSVELVAGRGQTSMPSDGNKNSGSGAKVRSLPPSHTLAMSASLIKSYFSSGPEKQQSKSAGSTPDTETSVKTKMIGLWNNVKYGWTVNLKTNFSRDAPVYLLGRVYHKSFGDMENSEEELEQHGIEAFKKHFHSLIWCTYRRQFPTLQNSTLTTDCGWGCMLRSGQMMLAHALIRHFLTRGKPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI07</accession>
    <name>A0A423TI07_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative dynein heavy chain 3, axonemal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_005416</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001701">
        <property type="protein sequence ID" value="ROT76027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI07"/>
    <dbReference type="STRING" id="6689.A0A423TI07"/>
    <dbReference type="OrthoDB" id="5593012at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000049">
        <property type="entry name" value="Dynein, axonemal, heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF70">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 2, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="13">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="14">
        <location>
            <begin position="96"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT76027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="337" mass="37766" checksum="45EF2CEF39E99C92" modified="2019-05-08" version="1">MTAQFLFSPYYASHLRAKAPSSRRWSDAAQQLSESLENVVGDVLIAAAVVAYLGVFTVDYREECLDKWHRKCQELGISCSANFVLYDTLGDAVQSRTWQLAGLPVDAFSVDNGIIHVISSLTITINPPTGQANKWIVSMEKENNLLVVKQTDPTFLQVVEEALQKGFPLLIEGIGETLDPVLDNVLLKRTFKQNGVDHVVLGDHAVEYHKDFRLYITTRLANPHFLPQVTNKVVLLNFLITRLGLENQLLGLVVAHERPQLEERKNRLLVESAHNRRALQKTQEKILEVLSTAGQNLLEDEKAIDIMSSSREEISKDHPAEHPLDPGCVPLRHSVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIX4</accession>
    <name>A0A423TIX4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_005005</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001665">
        <property type="protein sequence ID" value="ROT76411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIX4"/>
    <dbReference type="STRING" id="6689.A0A423TIX4"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="313"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT76411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="45880" checksum="9B18C2CD40A35FB9" modified="2019-05-08" version="1">MSEISGDGAPVDPGPLVTLESVEIPVIGTASTMEAFIYGSFTLLALLALALHFLSLKTKSQITSANNPHFKKFQYSFFLVYFMALFSDWLQGPYVYKLYEHYGYASNQIALLYVVGFASSVIFGTTTGPLADRFGRKKMALCFCIMYSFCCLTKLSSSFFWLFMGRVFGGISTSMLFSTFESWYVYEHTETHDFPSEWLSVTFSKATFWNGVLAINAGVFSNIFAETLAFGPVAPFMLAIPFLIMAGLIISQTWRENYGNQAIDLRKSCMEGLRSILFKDSILFLGVVQSLFEANMYIFVFQWTPVLGPGHPPLGMVFASFMVCIMIGSSIYSMLFSKKYSAEQLLLMAVGMAIVAMSLCIYSTSGNHLYLSFLAFLILEVGVGMYFPAIGYLRSQRGGNQNDKGGISWLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ46</accession>
    <name>A0A423TJ46_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein msta, isoform A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_004943</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001657">
        <property type="protein sequence ID" value="ROT76478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ46"/>
    <dbReference type="STRING" id="6689.A0A423TJ46"/>
    <dbReference type="OrthoDB" id="3174329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT76478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="503" mass="56735" checksum="519F7746233A2BFB" modified="2019-05-08" version="1">MVVCQNLKSFSSWYHVSSFGTDEIQIMGGSKANEEKGKCDSCGNEAETRCTGCRNVFYCGRECQKKGWSQHKDTCRPFAVNKKKDVGRLLVASRDLAVDDVILCEAPLVMGPKQMTEPVTSAAGVNLDVEMANAETPIHLYEVVTVLRCLVIASRDSKKWRASTERLNTRYLKAVGSPQYHHNQEYVVNALRDKFLLHQYPDVDASEAAIHTALGLLQINNIPTKTRYGEVQAIYPMSSLLSHSCIPNTKMQWENGRLTVRASDPIKRGDPITAIFTDILWGTRARQDHIQQTRLLTCTCKRCQDPTELNTFFSALKCRRCGGTVLPEKPLDDASPWLCRECSHEMTTEEVLGTNLALGAAVEVALTKPSITSLEALQKEWVQRVHPNHYHLHAIDKKEKVCKEFLTVCSRLDPSTQHTVPFVGLTFYEYHKTILQNAQRHFSQAKLTTQQLKKRMLLSKALLRKALDIFKNEPEDTPEGQLCITCEEEIIRIGKWMLAVGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJR5</accession>
    <name>A0A423TJR5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001622">
        <property type="protein sequence ID" value="ROT76683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJR5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="493"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="52258" checksum="27E334629B5037FC" modified="2019-05-08" version="1">MLCISSSLECNPRSMTDTRAPAGLFVSRLSSKLLLIFRNYYGETTRRWGGGGGRGRQASRIIPAARSLPSCPRSLGVLAPSVSSLLGVLAPLGVLAPSVSSLLAPRSLGVSRCPSPRCPRSPRLVSSLPRCPRSLGPRSSLLASSLPRVLAPSAPSLPRVLASGVLAPSASSLLSSLPRPLPSASSLPRCPRSSVSSLRVLAPSASSLPRRPRSLGVLLLAPLGVLAPSLLGVLAPSVLAPRSSLLVPLPRCPRSLVLGSLAPASLPRSSLPRCPRSLGVLAPSVAPSLLAPSVPRSLALASSSLPSASSLPRRPRSPRLAPSVPRLSRRPRSLGVLAPSASSLPRCPRSSASSLLGVLSRVLAPSASSLLASSSPPSLPRCPRSLGVLAPSVSSLLGVLAPRRPRPRSSLPRCPRSLGPRSLGPAPSASLAPSVSSLPRCPPRFPSCPRSLGVPAPSASSLPRRPRSLGVLAPSPRSLGVPAPRRPRSLGVPAPSAPSAARLLPRPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJS8</accession>
    <name>A0A423TJS8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001622">
        <property type="protein sequence ID" value="ROT76693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJS8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="42064" checksum="41380C4516FC271D" modified="2019-05-08" version="1">MAGSRLPLFLSLPLSIPLFYASFPFFSFSLFLLYSSPSLPTPISYLQILFPLHFSSLFLSLLPLPSISSSPLFLLSLLQFPLPSLLFFSPLFLLYLLLSPLPPLSSISSSHPSSFCLLLLLSSLPSSFYSFFLFLLLSSLPSPSISSSLPSSSSSLPLLLFSSLFLLSLLLIPSFTLPSISSSSFLPPLLFPLPSISFSDPLPSTLFLIPLSPSLPSLERPPSPPFYDSFPLSPPFLSFSIAPFFSPPLPSISSFSLYLLFLLSLLLILFLLSPFLFLLPPLLFLFSSISFSLPSSSSSLPSSFYLFSLPSPSSSSLFSSSSSLPSSFYLFFFPLLLFLLYLLFPSSSSSSPLPSISFLIPLPSISFSHPSSSLSSLTKTPSLSSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKM2</accession>
    <name>A0A423TKM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001580">
        <property type="protein sequence ID" value="ROT76993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKM2"/>
    <dbReference type="STRING" id="6689.A0A423TKM2"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000065">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="15834" checksum="E93F586863F85AA9" modified="2019-05-08" version="1" fragment="single">ERNAESAIEALKEYEPEMGKVIRANKSGVQKIRAREIVPGDIIEVSGKIRTQMAETEEIRTPLQQKLDEFGEQLSKVISVICVAVWAINIGHFSDPVHGGSWFKGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN38</accession>
    <name>A0A423TN38_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001464">
        <property type="protein sequence ID" value="ROT77856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN38"/>
    <dbReference type="STRING" id="6689.A0A423TN38"/>
    <dbReference type="OrthoDB" id="6344011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="12222" checksum="B2ED04297B02E5F0" modified="2019-05-08" version="1">MFKGVAFEVSNTNENGESLIKRHPPKKFQKLEDLQQGPALTQEQLEEKQAIAERRRQEILTQRVQSAKQRSARSAGRMRARNTDADEVETLDDGIIESAANVNSENEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNN4</accession>
    <name>A0A423TNN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001445">
        <property type="protein sequence ID" value="ROT78037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNN4"/>
    <dbReference type="OrthoDB" id="6368484at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019438103" evidence="3">
        <location>
            <begin position="26"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="227" mass="24614" checksum="DDC42B13831EBAA5" modified="2019-05-08" version="1">MSKGIPRWLLVGAACVLALAGRAEGRGIPCPQRAECKAICDRNGSDYRPQECSSCCDRSRADAMTVKENAVEDRLKTMETTVKELRVMTGVLLALVLLLILVVVAMLLHLTKNIPKFTLPVIFKNAKKGAANINDKNSTHKTCNGVADANAAVGRIANHQTSSSPKAKRASVRRSTYGPTEDTVGQHEPRSFRVRQPSESTFSTNTLDTTLPSESNLPSVVHNNTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TP68</accession>
    <name>A0A423TP68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Beta-actin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_003042</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001409">
        <property type="protein sequence ID" value="ROT78237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TP68"/>
    <dbReference type="STRING" id="6689.A0A423TP68"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0558">Oxidation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="19635" checksum="43BE567F8B33C921" modified="2019-05-08" version="1">MVQGRIRRRRRPSCRLPLHRRPPRHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEESPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDTGDGVTHTSPSTKVMLFLMLSFVSTWLVVTSPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPA1</accession>
    <name>A0A423TPA1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001401">
        <property type="protein sequence ID" value="ROT78294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPA1"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="119" mass="13123" checksum="FF5BB5DCF6C97EB8" modified="2019-05-08" version="1" fragment="single">MQVNSVDASEQDWPVFQVSLLPVLKEEGGNLHFLTSIRTKPSSHDVGGSYRESPERNGEGSHAQDLDSVAVSQRLQKAMLKMTGNFLDETTGKVNYASLRSSEEYRAYCAMAGQLRAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TPI8</accession>
    <name>A0A423TPI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002916</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001394">
        <property type="protein sequence ID" value="ROT78367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TPI8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="439" mass="46775" checksum="987277CCD02E572C" modified="2019-05-08" version="1">MMLPSIREFSILVPVLSAFLTPPPSTLDPPLLAFLLPCLLSLLLILPLSLSAILTLFLFYLVAIFTFFLFFSCCYFCLIPFPLLDSPPPPFPFLPYLSLSICCYSCPPLPPPAPLTPLPYCHYSCPVPIPRPTPQSTPHPPPLLSPSPSIPPHPPPPTLSLPSLPTPHPPHPCSPPFPSYPPIPHPPPLLSPFSFLPHPTPHSPCSPPSPSYPTPSPIPPLLSPFSFLPPHPPTPPPLLSPFSSYPTPSPCSPPPSYPTPSPIPPALSLLLSTPPSPPPPNPCSPPSPSYPTPSLPKPHPHPPPSLPPPSLPLPFLPHPIPPTPTPALPLPFLPTQSPPALPFPSYPTPSPIPLLSPSPSYPTPSPPPHPCSPPSPSYPTPSLPNPHPPIPPSPTPPSSLPFPSYPNPSPHPHPTLSQTPFPHNPFPSPADPSCWVILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSB1</accession>
    <name>A0A423TSB1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001256">
        <property type="protein sequence ID" value="ROT79340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1467"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1552"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1597"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1088"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1467"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1525"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1624"/>
            <end position="1648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1746" mass="185500" checksum="1ABAA1936EF4A16E" modified="2019-05-08" version="1">MSVPLPHFPSTLNSLSSPSNLPKAPSHPPLQLTFSFFPLQSHPHSDLTLTPFSPSLPSPHSISPSLHSLPHSNLTLTHHSILSLTPISPSLILSLTPSDLTPPSLHSLLTPISTLTPFSPSLQSHLSILSLTPFSLLTPISPSLHSLPHSFSPHSNLTLTPFSPHSILSLTPISPHSTPHSSSLSLHSLPHSNLSLTPISPSLQSHPHSNLSLTLHFNLPHSSSLQSHPPILSLTPFSPSLQSHLTPFSALTPISTLTPFSPSLHSLPHSNLSLTPFSPSLQSLPHSNLSLTPFSPSLHSLPLLSSLQSHPHTPFSPSLPSLSSLQSHPHSNLTLTPFSPSLHSHLSSPLSLISPHSILSLTPITLLPHSILSLTPISPSLQSHPHSILSLTPFSPSLQSHPHSILSLTPISPSLHSLPHSILSLTPISPSLHSLPHSISPHSILSSPISPSLQSHLTPSLPHSILSLTPLSPSLHSLLNSNLTSLHSLPHSNLTLSPLTSLILSLTPISPSFSPSPSLHSLPHSILSLTPFSPSLHSLPHSNLTLLPTHPHSFSPSLQSHLTPTHSILSPTPISPSLHSLPQLHSLPHSTLTSPSLTPFSPSLITPHPHSNLTPHTPHSILSLLHSLPHSILHSLQSHPHPVSPSLHSLPLPPHFILPHSNLSLHLTLTPFSPSLSISPHPLSPPHLSSLTPISPHSFSPHSNSLPHLSLTPFSPSLHSLPHSNLTLTPHLLHLSSLHLSLTPFSPSLHSHPHSNLNSLPHSTLSPSLHSLPHSFSPFLSLTPFSPSLHLILTPSLTPFSPSLHSLSLQSHPLHSLPHSILSLTPISPSLHLTPISPSLHSLPHSILSLTPISPSLQSHPHSILSLTPISLTQSHPQLHSLPQSHPHSTHSFSPSLHSLPHSLTLTPISPSLQSHPHSILSLTPSLPHSILSLTPSPHSILSSSNSPSLNLSSLNLTLTPFSHSSLIHSSLTPISPSLILSSLNLTLTPISTLTHSLLSPHSILPHSNLTSQSHPHSFSPSLQSPLTPFSPSLHSLPHSNLTSSTHSILSLTPISPSLHSLLTPFSPHSNLTLTPISPHSILSSLQSPPSLHSLPHSKSQPSLQSHPHSNLTLTPISHSTLTPFSPSLQSHPHSILSPHILTLTPSHPHSNLTLNSTLTPISLLSPSLHSLPHSNLTLTPFSPSLHSLPHSNLTLTPLHSLLTPISPSLHSLPHSISPSLHSPHPFSPHSHPHSILSLTPISPSLHSLLTPNSHPHSNSPSLNLTLTPSLTLTLQSHPHSILSLTPISLTPFSPSLTPFSPHSNLTLTTHSISLTPFSPSLHSPSLLTLTHSLLTPFSPHSISPHSNLTSSISLPPPLHSLPHSILTLIHSLSNLTSLQSLPHSISPFSNLTLTPFSPSLSLTPFSPSLQSHPHSILSLTHLTLTPISPHSSPSLQSLPQSNLTLTPISPSLQSHSLNSLPHSLTLTPFSPSPTQSHPFSPSLQSNLTLTPFSPSLQSHPQPLTLNPFPSITPPSSPSSHPHRPALSAHHTPPAPFLHSYPPHLLPSHPSYPFPSTPSLTPPSYPFPPTPLPQTPALPLVSGFGGLGPHPLPHTPTLTLFPPLPHPRTPVPTSRERLGGVGPHPLPLTPSLTPFPPHSPPLTPPSHPRPTSRERLGGVGQTHDGGQGVLVEQRGHDGPIALVEGVEAMQEGGVQTQHQPPPRARAHAPDAAPLQLGLKRGEGNDQGWGLSALRAVCAVASVLVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU71</accession>
    <name>A0A423TU71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">FGLa/AST receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_001243</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001165">
        <property type="protein sequence ID" value="ROT80018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU71"/>
    <dbReference type="STRING" id="6689.A0A423TU71"/>
    <dbReference type="OrthoDB" id="2132067at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000405">
        <property type="entry name" value="Galanin_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF23">
        <property type="entry name" value="GALANIN-LIKE G-PROTEIN COUPLED RECEPTOR NPR-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00663">
        <property type="entry name" value="GALANINR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 12" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 12 17" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="11 12" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019132755" evidence="15">
        <location>
            <begin position="19"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="16">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT80018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="362" mass="40464" checksum="2CA5F010F2CBFD8D" modified="2019-05-08" version="1" fragment="single">LAAADLLFIVFCVPFTASDYMLKSWPFGRVWCQTVQYLTYVTAYASVYTLLLLSFDRFLAVVHPIAALTIRTERNALYAIAGSWILILGSCVPVYTCHGTKRINFDDEILITCSFLNEQCNHMAFHIAFITSMYFLPLTVIVVLYLLILNRLWFGMQPGGNRSAESIRGKKRVTRMVVIVVVTFIVCWFPIQLVLLLKSLGMYQMTTFQIIMQIAAQVLAYINSCVNPILYAFLSDPFRKAFRKVISCGPQRRAAINGRTDFERSMETRPLRPSPNAIPMTNMASSDQLLTPSSAILRHETTCTTTTSFTNGAAREDGGAKRTQSQEKLLNKLVVNSPAQDYGGVGGGGQSEHNSLERAHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVE6</accession>
    <name>A0A423TVE6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Gamma-aminobutyric acid receptor subunit rho-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_000816</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVE6"/>
    <dbReference type="STRING" id="6689.A0A423TVE6"/>
    <dbReference type="OrthoDB" id="6349664at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019481818" evidence="11">
        <location>
            <begin position="21"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="12">
        <location>
            <begin position="39"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT80421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="369" mass="41078" checksum="4990FCB5240CE4C5" modified="2019-05-08" version="1">MAANLLKSLIYATLFVSATAHNSTPEIPTEEWTTYTGPNYRKEVFPKNDTSEPLEVGISVLVRNLPKIDEVNGVMFMEVNLRVKWQDQRLTIPPWLGAEDYVPLDPVILQDIWVPDLYIDHSSEAITPSVLTSIASVWIYGDGTVDYSGNMFIRVACRMNYTWFPRDHQICSIRIESCTYPALAFRVHLTRQITYVLLQVYLPSGLFVVVSFVSLLVPPDAIPGRMTLCITTILTMSALLGVAMQSTPQVSYTRAIDIWLLVCLSIVSAVLLEFGIVIKLREREKIQAKSQPSGRLMKTVSTQVQPISGNAAVSEKESARFTFSSDVVEKASLVVLPLVFLVFNGAYWSWFLTGSEAAMPRGLSANGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TXZ8</accession>
    <name>A0A423TXZ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000990">
        <property type="protein sequence ID" value="ROT81325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TXZ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="42842" checksum="F3C63354E95BA02D" modified="2019-05-08" version="1">MPTLSTSQPGASATHHITSPPYPPSYSRTNPPYTTSLSLQQPIITKLTIPTKTTTSQYPAYRQRITHTNYNLLPTHPLRPADCKTQTYPPSPRRSAPPQSNYPTDTQDQHQTTTKPHGPQHKRYLDPPLSLPPLIDPYLLKSRERPSEHPTASDLILPRWTPIPLRAHEPTPAQATAITRETEISTLRLIIVSKANAGGGGSPEQIQSGTRREKRGGGKQQLPEKDRTEHRRNKNREKATNTQHRPPSNDINPHTAHHRTTNEQPAQRTNKQQTAHTTRDHGAQKMRREHSQGNHPHKHQTTIAHPTQAKHTGKEEKRRGNDKKGERGAQEPNKTLTHTKDSRTKIEKNREGIQEFPFSRRGLRVNILLKVVAWDLLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZH6</accession>
    <name>A0A423TZH6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger, CW type with PWWP domain 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_024999</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000912">
        <property type="protein sequence ID" value="ROT81844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZH6"/>
    <dbReference type="OrthoDB" id="6382749at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20145">
        <property type="entry name" value="PWWP_ZCWPW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042778">
        <property type="entry name" value="ZCWPW1/ZCWPW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999:SF2">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07496">
        <property type="entry name" value="zf-CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CW-type" evidence="6">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="PWWP" evidence="5">
        <location>
            <begin position="206"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT81844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="317" mass="37113" checksum="80898B343FD695EE" modified="2019-05-08" version="1" fragment="single">MTEEQWNDLFSSVINLIDQDTLDSAIIQVDCNQEPQKLETDNRCKGKKRKSMEEVKHGDGVHECAKDFEALQSMNVKPLLNISRIYKRLAGYQNTEELSPPDRARQSKRSSESSNNSDSPEYVISSEQCSRKMELLQMIHHMDEDVWVQCDKCSKWRKCWNNCDPSALPEFWTCIMNKDPLHNRCGIPEENWKDTNEIYLYHKYILGSVIWACIPANPWWPAMVDLDPEYKCYLWGKSEKNHPMYFHVTFFGEPVSRAWVTSKSVTPFKMKHTARRFTSKYPRGSVMNAELEEAVFEAHSALRMDINDRRKKYSFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1H8</accession>
    <name>A0A423U1H8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative SE-cephalotoxin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000805">
        <property type="protein sequence ID" value="ROT82552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1H8"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039051">
        <property type="entry name" value="SE-CTX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40472">
        <property type="entry name" value="RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40472:SF6">
        <property type="entry name" value="RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019341950" evidence="1">
        <location>
            <begin position="23"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="566" mass="63893" checksum="16C2794F172C731A" modified="2019-05-08" version="1">MKFFPLICSMVVFVLLELRALGALIPSLHPDGILQEDVQDPQDNPLEVSDSTSVRYPEVSTEKPEGELKYNLTSGDIAKRIAGLELSRDVLDAVPDSWQSIAVEKTELGLDTLSDYFLKPATSRKFKGIAKEIVKKVTKFLPSFIKALGTASTIFGFISVFFYPSVEDILKEEFNTVNQKLDALSLKMDNVREELESSMEFQTWFTSYNDYKNSIENVDMKLKSTLSQITDAIEIKDKLKVAKEFLDYYRTQDVEGALNNIFRLTATRGTPTKPNLFKLYIRQYDCNVTGLSHLMLVIMSLVFTGTQLMYAYSFFRNNNLNQLEEQVEAVYEQFYNVRRQYEDQVFHCYKTAIVRADRKARDILIDNPKLTGAPLTAKIQLEISELVPWYNWTVVQYSEIGSISLSKRHCAVESRGKQIFTVKRGERKVLVLWEDRGNRECYDADKANTFVPFKLCDGCNNTVFQGSEKTLNGKSCPNYLTETVQETERSCGSDSSTSEVNGLINSNKYSFVAGGFSSDQLSNTEMRCVAVMGPANPFPTVTTICVSVPPIFGVKAVRLGTTPLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2A2</accession>
    <name>A0A423U2A2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine palmitoyltransferase 1</fullName>
            <ecNumber evidence="5">2.3.1.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Long chain base biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Serine-palmitoyl-CoA transferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023997</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01000771">
        <property type="protein sequence ID" value="ROT82836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2A2"/>
    <dbReference type="STRING" id="6689.A0A423U2A2"/>
    <dbReference type="OrthoDB" id="3168162at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000049">
        <property type="entry name" value="serine palmitoyltransferase 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF2">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="15">
        <location>
            <begin position="97"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00041765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00042649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT82836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="472" mass="52819" checksum="EDE6B62F20790D88" modified="2019-05-08" version="1">MASQWNVYESFQALLQAGPYHLALEGVLVLCIIWLFTAKKQPSKLVRLTKKEEEELIAEWMPEPLVPNPPPEDHPALHTRTVYGKAGKYLDLGKGEKLLNLGTHNYLNFGERPEIEKAALECLHTYGVGSCGPRGFYGTTKVHLELEERLAEYFNCEMAVLYSYGFSTSASAIPAYSKSGDIIYADEMVNFILQRGLQASRSRVVYFRHNDINHLEELLEEQVKQDKKDPRKANATRKFLVVEGIYMNSGLMCPLPELVKLRQKYKLRLFIDESITFGTLGKNCRGITDHFDVPMKEVDMIMASLETSAASTGGFCVGTKFVIDHQRLSGLGYCFSASLPPMLAATSIKVVDILEKEGGDLVAELQDKCRLMHNKLKGLPSKVTVTGEDISPVKHLRLVDSSEREVEEQILRDIAEKAENYGVALTVSSYLWDKEANPPKPSIRITVNKDLTEDEVEKALDAITKAVTDILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U351</accession>
    <name>A0A423U351_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine proteinase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023696</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000733">
        <property type="protein sequence ID" value="ROT83126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U351"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023795">
        <property type="entry name" value="Serpin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF278">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR 88EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00284">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019384162" evidence="4">
        <location>
            <begin position="21"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="5">
        <location>
            <begin position="46"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="48039" checksum="3DF124FAA4F4DDC5" modified="2019-05-08" version="1">MRWILAAVVVLGASVWEATSQCLTDEDRIKILGVNQELNEVVDFGLELYKELELGQATSYLATGRNLFFSPYSVWSALVLAYFGSGGTTEAELQKALGVVDKINILTKMRALELTYDLRRSTGSSYIFNVANRFYIDAASPVRKCVKNILFKEIAETDFRNTFVAANDINEFVSETTQGNIPRLLEESDLRDAQMVLVNAAFFKGIWKYSFLSNDTFLAPFRADPSLSFQGGAGTPPNGTGMVSMMNQTASFKYADSKDLEAQLLELPYEGGAMSMFLMLPNEEGRSGFARTVASFSSAALSKAMRTMKPETVNLQLPRFNMSVELIDELEAALKNLGIRNVFDPEHADFSAFAPTPRMSVSKTVHKAFIEVNEEGSEAAAATVLAVNIRTRPKPPLSFVCDRPFIFFIYDNDTENILFLGVFRNHKEALDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4U0</accession>
    <name>A0A423U4U0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NMDA receptor subunit 2 variant C3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_023101</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000641">
        <property type="protein sequence ID" value="ROT83728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4U0"/>
    <dbReference type="STRING" id="6689.A0A423U4U0"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="12">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT83728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="249" mass="26602" checksum="928C15EA20B89DDD" modified="2019-05-08" version="1">MQLGLSPATEAPPRRPLRFRAPLSGPAAFVLTGIVSADGNGSGPVESAVYCGKSERFGYKWNGLVAALMNHKADMALSSFKINSERESVIDFTVPFLESGIAIVVAKRTGIISPTAFLEPFDTASWMLVAFVAIQVAALTVFLFEWLSPGGYNMKRFAVSCLAVVSPCSAVGRLPARSCKDLLIDSLCNMSWGLTTDESTNTFANTFSRPAIGAASAREKKSLSQELHGFLISRSSLHSWADATEGEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4Y5</accession>
    <name>A0A423U4Y5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023047</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000633">
        <property type="protein sequence ID" value="ROT83768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4Y5"/>
    <dbReference type="OrthoDB" id="6366976at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="62429" checksum="F17C6DEB50E773C3" modified="2019-05-08" version="1">MICGPRGLRCPIPTPFLGISVGILVSFLSSLPPPFFSPSPSLSLFFLFHLRLSIPTRSWESQLESSSPFSPLPPPPPFSLLPLSPFLFLFHLRCPIPTPFLGISVGILVSFLSSLPPPFSPFSLSPLSLPFPSSLSHSYSVPGISVGILVSFLSSLPLPFSPSPSLSLSLPFPSSLSHSYSVSWESQLESSSPFSPLSPPPPSSPSPSLPFSSFPSSLSHSYSVPRNLSWNPRLLSLLSPSPLPLLPFSPFLFLFHLRCPIPTPFLGISVWNPRLLSLISPPPLLPLSLSLPFSSFSIFAVPFLLRSWESQSRRRGTHSPSLALTVSSIPLDGRECKSNLVTDRFLASRPDVNAKEKCFLGAVGLFSCGGLAWCISLRQKKEIDLEPRENAYLWFRPEEESAHVTFFIEPETIEPWSFVVTNTSLLKTIFLSQPTQHRQGRIVGPFITTTTFGFDSISKLSVSSNITVFFNVCTSPYVCAAPPVSSSSEIQRAVLIVFLVVALVVASVEAVYIWYRKHKEGAPSPSTKDGCESIESDALYEEWNDNWLSYVADTLNITYLFQLTADFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U567</accession>
    <name>A0A423U567_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Metalloendopeptidase</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_022945</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Metalloprotease.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01000631">
        <property type="protein sequence ID" value="ROT83863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U567"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.390.10:FF:000015">
        <property type="entry name" value="Meprin A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 12 13" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018818491" description="Metalloendopeptidase" evidence="13">
        <location>
            <begin position="24"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="15">
        <location>
            <begin position="65"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="14">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="14">
        <location>
            <begin position="314"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="14">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="274"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="314"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="355"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="43504" checksum="4F82116C6623CCF0" modified="2019-05-08" version="1">MKTLKVTSVVTFAVTVLAQFSRAQLLSRSRLPKVIIGDPNEGDIMLPSEDHLLQIIQGSPDAQGSAARNPALRWPGALIPYVISASFSRAERAAIGGAMGEYHTKTCLRFVPRQPQHRDYVHILKGEGCSSAVGRAGGLQVVSLGQGCVHHGVIVHEFMHAAGFWHEQSRYDRDKHVVINWKNIIGDMKYNFGKKTNRLTSDLGLDYDYASVMHYGPRAFAVDASLPTIIPRVAGVEIGQRRGFSQLDVKSLNILYRCDKDATTPAPTEKPGACEDTHAACPKWAASGVCVSSPVFMSRACRKSCNLCDEKAECTDTNIHCAWWAGRGECERNPAYMTSSCPRSCDACGVWAGPCKDQHKDCSIWAARGECGRNPEYMSRNCRSSCSLCGEPPRAPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5E2</accession>
    <name>A0A423U5E2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000623">
        <property type="protein sequence ID" value="ROT83915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5E2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1099" mass="115510" checksum="77681E5A4DF6926D" modified="2019-05-08" version="1">MLSGTPPSLFWHSPSSLALWQLPPSPRSWHSLLPSLATLLLSHLWHSLPVPTPRSLATPPSSLRSSGTPSTPSLSCTPPSLPRISGNSLLPSLILALPPSLRSLATPPLLALWTPIPSLCWHSSLPPQLSGTPSLALWHSRPSLPRLWHFPPSSHLWHSSFPRSSGTLPPFLLALWHFLLLACGTPSLPPSLLWHTPSFLASLATPSLPSHRSHGTLPLALWHSLPPSLSWHSSLALMALLASSARSLALPPSLALGTPSLPRLMASLLPRSRGNSLPPSLSWHSLPPYALWPLLPPSLSGTPPSSLSGHPPPSLSGTPPSLPRSLALPPSLALWHYPPSLPRSLWALPPLPRFSCTPVPPSLSGTPSLLALWTLPPVASWHPSLLALWHSSLPRSLALPPPLALWHLPPPPFALWHSRPSLALLATPSSLALWHSLPPSLSGTPSLPRSLATPHSPALWHSLPPSLLWPLTIPRLALCTPSSLALVALPSLLALWHSSSLTCSGTPSLSRSLALPPRSLSWHSPSLALTGTLPSLALWHISPPSAHLALRPIPPLSGTPPSLALYALPPPSLSGTPLPSLRSLATPSLLPLASLHSPPSLALLVLPPPSSHGHSPLPVALWQLPPSFLSGTSHLPSSLASSLLSHHLALPLPSLSWHSLPIALWHSLPPSLSGTPSLVLWHSSLPSLLWQLSLPPRSLALPPSLALWATSSPLALWSLPSLPRSLALPPSPSPLLALSSLPRPLAFPPPRSLALPPAIPSALWHSHPILSLSEHSPPLPLPGTPSPLALSSNPSLPRSHGNYLLLRSLDSPPSLAILALPPSLALLALPSPSSLSGNSIPSLDFWHFLPSSLSGILHPSLSGTPPSLALWHSSLPSLLCTPIPSPRSLALPRPSLALLALPPCPRSLALPPFPRFLALPIPPSLILHSLPPSLSGTPFLPRLWQSLLPLGSLALSLSPGTPPFPALSALPPSLASGTTLPPRSLALPPSLRISWPPSSPPCCSLAPSSLALWHSPSSSPLALSPPPRSSGTPSLPPSLSGTPSLPQLSGTPSLPRSLHFPPSLALWHSHPPSLLSTPSLTSLPLHSLLVPRSLALPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6N5</accession>
    <name>A0A423U6N5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000548">
        <property type="protein sequence ID" value="ROT84398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6N5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="513"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="601" mass="64407" checksum="69FF6702E205809C" modified="2019-05-08" version="1">MRVLAVTLGRSRPRHNESDDAPPPPTAARQAPKEDSVSLLAPLEPQPGRDAGARRGVGRSANIKYCQDLPSASPTRRSVKEMDKGVLRSTELSNSPAVSPPSDSAKSAKVTRLPRETMCNHRSSKLVRNSSISRWRAKFRKNALSPEGSSGTDTEQLLDEVEDASRPSLEVIVGPEVMCAPAGWAGVVPPPRCLTPHRVQLGGALIPWVGSIQPQGSESPYYLPMGGGHAVASGPKGLPYQVNGGDASPPCYERPLPPAVGRAAASAEAGGTGSWPRSSRTHAVLDLRDVRANPSRPTARRDDCSASLVGELPGGTTTPSAGGDCSHFGTFPRRRPPQKARESPESAAQASRLCLEYHRKRAAAERSVIVCYSSYRTLARSRGLLSPSSSQCDVHFCPRVLSLVLKYLSQSRCFLIAGALRPHRKNARNVFLSSVSSFLIFHSSQRTFMEVLETRPRVDRRGEGLHGASLRRSGSDKCSPAKLIYIASLSEAASRSLLRRHVSLPVPGLAPARCPGRPVPPLERPGGKRPNDGCCPSPSASPQTRTQMATYTYVHALAPRLLLSLCTHARAHVQHGSGCLLWRDLVSKVRGAGAGLRGAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U737</accession>
    <name>A0A423U737_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative gamma-glutamyl hydrolase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022299</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000532">
        <property type="protein sequence ID" value="ROT84505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U737"/>
    <dbReference type="STRING" id="6689.A0A423U737"/>
    <dbReference type="OrthoDB" id="64220at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034722">
        <property type="term" value="F:gamma-glutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046900">
        <property type="term" value="P:tetrahydrofolylpolyglutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015527">
        <property type="entry name" value="Pept_C26_g-glut_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11315:SF0">
        <property type="entry name" value="FOLATE GAMMA-GLUTAMYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11315">
        <property type="entry name" value="PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51275">
        <property type="entry name" value="PEPTIDASE_C26_GGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR615527-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="20978" checksum="F20FAF61CF82C389" modified="2019-05-08" version="1">MFQEVPTLSPAPVGTEAAGAKIFQLVLEANARGVYLPLWGTREGFQMIAYLAAGEQNLTTPCSAINKADSVTVAEGYMDSRIFTQMPDYVIGYLTFSDSTVNFHRKCMTPENFTNSGLTDEFKLLGTSFDFDGLEYVSLIEHVALPIFGSQFHPEKSQFEWKDDEVHSAIPHTPQAIGVGQFFPLIFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9E9</accession>
    <name>A0A423U9E9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000312">
        <property type="protein sequence ID" value="ROT85319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9E9"/>
    <dbReference type="STRING" id="6689.A0A423U9E9"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="478" mass="51203" checksum="926D3379F0F3AB87" modified="2019-05-08" version="1" fragment="single">NEPTKSKKNRRRGKKIKKALNGTSAKETQEKLNSIVVEVDGSDDEIAFKTPPNMVKKFVKITPSSPANKIHTHEGKSTATEQSLVKSLFSKKKGLPSTPNKAEDMLEVATPQTVKLTPGTKKLGKKVKTAETTPSKSEEEPTAILKKTPKKNAKTPGTPSASSALDQVTEEPVSATEASVGESEPVEAKSPKSTKTSVTPKKTPKATQKTPKKVPGTPADENKPVEAKTPITTNPSVTPKKTPSKATQKTPKKVPSAPSDESKPVEAKTPEAAKIPKTPEAKTGKTRTPKSAKRKEENIDTVAQLDAANDKTPLKRTVEEPQAKELFKKVKVDSTEQTTTPKKSTETPVTPSASSASDKVAEETVETKAAKSPKTPKTPKAKIDGTKTPKSTKRKADNPLGHSDGPEALPTPAIEGTPRKKTEEPQGQDLKKLKVDPTELASTPARTPKRAVKKTPKVDESSTTPLRRSLRSGKNNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBA8</accession>
    <name>A0A423UBA8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RAS-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023983</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Lipid-anchor</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000077">
        <property type="protein sequence ID" value="ROT85998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBA8"/>
    <dbReference type="STRING" id="6689.A0A423UBA8"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000080">
        <property type="entry name" value="Ras-like GTPase Ras1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT85998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="193" mass="21946" checksum="71C75F1E74D49A92" modified="2019-05-08" version="1" fragment="single">MSKPPSDKLPTFKLVVVGDGGVGKSALTIQFFQRLFVTDYDPTIEDSYIQHTEVDAQWCILDVLDTAGQEEFSAMREQYMRKGDGFMLVYSVTDKQSYENIPHFYTQILRVKDRESYPMLLVANKVDLVHMRKVSEEMGRELAHRLNLSYIETSAKDPPLNVDSAFHEVVRIIRNSPPVYGPPKGKGKGKCVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-02-13" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3G2KWW0</accession>
    <name>A0A3G2KWW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PDGF/VEGF-related factor 1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Vascular endothelial growth factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">VEGF4</name>
        <name evidence="4" type="ORF">C7M84_004046</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2018" name="Fish Shellfish Immunol." volume="84" first="259" last="268">
            <title>Identification and characterization of two novel vascular endothelial growth factor genes in Litopenaeus vannamei.</title>
            <authorList>
                <person name="Wang Z."/>
                <person name="Li S."/>
                <person name="Yu Y."/>
                <person name="Yu K."/>
                <person name="Zhang X."/>
                <person name="Xiang J."/>
                <person name="Li F."/>
            </authorList>
            <dbReference type="PubMed" id="30308291"/>
            <dbReference type="DOI" id="10.1016/j.fsi.2018.10.019"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <dbReference type="EMBL" id="MH475138">
        <property type="protein sequence ID" value="AYN64309.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01000154">
        <property type="protein sequence ID" value="ROT85909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3G2KWW0"/>
    <dbReference type="OrthoDB" id="6346729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000072">
        <property type="entry name" value="PDGF/VEGF_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50278">
        <property type="entry name" value="PDGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033378263" evidence="1">
        <location>
            <begin position="18"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Platelet-derived growth factor (PDGF) family profile" evidence="2">
        <location>
            <begin position="55"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AYN64309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22613" checksum="22F497F2942E734E" modified="2019-02-13" version="1">MIRILTLVVLLAVSVYGGQKCWDRKENRNIRDLVRKVSCMEPRKTLVPLPVPKGFDRVYPSVVEVPRCAGQMCIQLDQECVATETKNMTITVEAHRLNSLMEHECVDISVQEDVMCGCNCERSQESCGINKVFNRNFCRCECKQGLKNECKNKMVENPGLFMWDETSCTCPCNNQHVKCGDGQVFVHETCECRYVMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQG4</accession>
    <name>A0A3R7LQG4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Caspase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQG4"/>
    <dbReference type="STRING" id="6689.A0A3R7LQG4"/>
    <dbReference type="OrthoDB" id="6114029at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF8">
        <property type="entry name" value="CASPASE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Caspase family p20" evidence="6">
        <location>
            <begin position="306"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="53048" checksum="2AB3260A8B2896EA" modified="2019-04-10" version="1">MSVNNPTPGSVDQGFLSKVRDEDVPKMLFLSVNPNKIEEQGTTSAASGYTDGVSIGKKVVVSEFRSEETSDSVTRLIEKFEKSLSEKSITPVRRELQLRILKLSSVELNTNTLSTLESNFSDENDQLSNDEEDILEFTEIFEMFNLSAPENIKVNFGNIISSKKIPLKRGDIGNYSKKTFFVYAENKIMMKICDSLSPLDVYRLYEIIRESKATENDDKVKDLLSQQIDQRALEKVRGLKDVAFYYLTLTMMRKQLLNRLYTHRLAFLFDQLKEMKSGKDPNIDRILDTLNRYPVASRPPGLCIVFNMLQNREGAAKDLTKVKELFEKEYKYDVFVKVDPTAEEIKTIVSKLKAARNKFYDSLVVWFMGHGDKTYLTVKNEQRIHRRTDLIQPFTEIEWFNKKPKLFFIQACAVKKDRKRFSSTSQPKELQGLQASTDSIGWRARPVASGRISTRATPTSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LV95</accession>
    <name>A0A3R7LV95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003093">
        <property type="protein sequence ID" value="ROT65373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LV95"/>
    <dbReference type="OrthoDB" id="6382424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="711" mass="77130" checksum="4191CFD16177FB10" modified="2019-04-10" version="1">MNTLSLDSSLANKSVGPVDSGSRYLPVSGSHQFQHDPSFPELQARLVGTAPTPKPIIAQTELDSASGEGFSAPYSSHMYPNTVQIIGEGSQRPPSISVESPSHHLSRPFQTHFKKQLISSTQNSATIEGVAHEEQPKSTDPNQKHDQGSLGRLPHHESAPVSQPNPQPNRFEAYQSSSTCSYAGLVPRPGALLEPSFLKMNQAVPPPVILTQNRQVPIGHPVGAPGPSPVVEHDTRSVDSLGSVELPQTLPSHPSGTDLDGRLPATPVGHIRLIRGSPASSSSSKSRSDWSRESTPSVNSFKIPSSSPYSDPQTQQTSPLSLVIQKVNSAGNSISTILHDDLINRSSIQSGTEVAPRESQQTPLSYVPAPVPLSVQEISVRDKRLFPIRKRSVQIVSEDNKDPEIQCQGTFTSQAQVVSLVRVTPSPASCKENDVKPPEENVQSMAPPSVPGITPLLPHPRYHPHALKLRPELGGRAIQMYKERPFMRGSILTTSKAAPPPLLSPGDHGHRAGVYPPQQPPNRPHIGSKEDLTTPNLGKEDQGHPFWRYGSSSDLRDLPIHMDPALIPIRWPGMSSEIAAQLKAPQNLAPLYRPGINSYLFRGRFAQGSLLPPNYPSQMYQQPCSLPEGHRPHSNETTVKPDCVKETKPSQEVSPDDSPINVVDEAPELLPASSIGSEASKLEGLGKSLQHHLTSQNFLQMEKQRYPSLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYY9</accession>
    <name>A0A3R7LYY9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative programmed cell death protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013514</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002683">
        <property type="protein sequence ID" value="ROT68352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYY9"/>
    <dbReference type="STRING" id="6689.A0A3R7LYY9"/>
    <dbReference type="OrthoDB" id="366284at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052815">
        <property type="entry name" value="PDCD2-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46421">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46421:SF1">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="324"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="46823" checksum="C5AEAF7D63C1C3DF" modified="2019-04-10" version="1">MASKPQLVLLGYVDEQITSKYQQVVNFTTSKIGGAPDWCISGSSIPICKRCGRRQSLVIQIYCPLEGSPYHRTLFIFACVTQECWNRPHSWTCLRSQIPDPTSSKTSLPSTKAVPPQSAGGETWFEDDDDWGSNDNDGNGNADNYNFASSSQLYLDNMAKKPDGMSNLNNMNSNTSSITEVAQSMESKLNIIEGDANANEALCGAVGIVGCGGEGVEASAVIEGSEEDMIAVDTPEQPTTDIPALFQEAAQIDANADVTFIPYFLSSEIEPPEDVSFTDHERELLVRYTHSTGHDFREEENAGGGEGKGDGVYEKDVAIHGDVLLHKFKKRISRSPQQVMRYCREEGASPLWLRPPGASDVATKCQHCGGSMVFELQLTPQMIIHLRVSGVQGTPLEFGTVTVFTCLASCWSDKDTVRQEAIVVQSEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZN5</accession>
    <name>A0A3R7LZN5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002621">
        <property type="protein sequence ID" value="ROT68926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZN5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="48328" checksum="6538FDE8BEBA768F" modified="2019-04-10" version="1">MAVFQRMLEIRALASHRSPRPLACGNMSPVAYWTRATFGLRSLTLSPTGMGTFFLWVDKLSYQHPLRSNRITKPSELHSFIALAPHTLAGAGLFVRIVRGPDAGVRALRSCPTSSLPARRPPSPPERSSLPGRRPLSLADVLPPRRCSPSLADVPLSPPDVLPPARRSSLPWSDVLALPGESFPPLATFFPPRPTLPSLPPDVHPPRPTITLPPRRRPPPPATVPPPRPTSSLPGRTSSLPVRTSISPWPTSSSSLADRPPSLSDVLPSPPRRPPSLPTSSLHLPTSSLPSRRPPLPADVLPPPDVLPPWPTFLFPGRPLCCPADVLPPWPTSSPPPTVPSPRPTSSLPARPDVLPSLADVPPSLGRRPPPPPDVLTSRARRPLSLRPTSSLPGRTIPPPGRRPPSLSGRPPSLPTSSLPARRPPSLPDVPPSTSRRRSSLSLGHLARAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1J2</accession>
    <name>A0A3R7M1J2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Integrin alpha-PS2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_017357</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003207">
        <property type="protein sequence ID" value="ROT64694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1J2"/>
    <dbReference type="STRING" id="6689.A0A3R7M1J2"/>
    <dbReference type="OrthoDB" id="6349939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007157">
        <property type="term" value="P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.930">
        <property type="entry name" value="Bicelle-embedded integrin alpha(iib) transmembrane segment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1510">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1530">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048285">
        <property type="entry name" value="Integrin_alpha_Ig-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048286">
        <property type="entry name" value="Integrin_alpha_Ig-like_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032695">
        <property type="entry name" value="Integrin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220">
        <property type="entry name" value="INTEGRIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23220:SF133">
        <property type="entry name" value="INTEGRIN ALPHA-PS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20805">
        <property type="entry name" value="Integrin_A_Ig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20806">
        <property type="entry name" value="Integrin_A_Ig_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69179">
        <property type="entry name" value="Integrin domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 9" id="KW-0401">Integrin</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha second immunoglobulin-like" evidence="7">
        <location>
            <begin position="22"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin alpha third immunoglobulin-like" evidence="8">
        <location>
            <begin position="219"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT64694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="54789" checksum="1B73BD783E508AE0" modified="2019-04-10" version="1">MSRFWRRERIRHFWREIGVAFDFDEYVLGSRDNLVLMTGVSNEGEDSFQTKLHVRVPRGVTFSKFLVTSNTADDVTPICSALTREDDEERTTRRCVQEAKESEKQEACFGAQGIKGNQVVCDVGNPLPSGKEIALQLVFQPNPEAIISARLTVLPFNVTATSTNEELHGTELDNHVMKELQVTVRSDIDIKGISWPDGAFDYNASRFGMGLLGEGERVTHDWQVGPEVTHVYDVTNQGPSDLPQAQIFLLWPTRTLGGDPLLYLLEEPDVSSEAVCHSVPDVNYLGLTVAEATYDHLITAPELAAQVGSSFLHVTEESAALHAKHRTRHGHRLRRSQRRRLEDELSCGPTNCTRVMCTVSPFRAKSNIIIRVRSRLWVDTIEKLGRSEVKITSRLVIAGMGMAEEDEAGPSWGDVEQLWAGTVTTLVRTGPEEHVRSLKWVVIVGSILAGLLLLALLSAILWALGFFKRKRPQDKSDSEPLNGNGFYSNGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2B0</accession>
    <name>A0A3R7M2B0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003100">
        <property type="protein sequence ID" value="ROT65321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2B0"/>
    <dbReference type="OrthoDB" id="6435011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41142">
        <property type="entry name" value="SI:DKEY-16J16.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41142:SF1">
        <property type="entry name" value="SI:DKEY-16J16.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="321" mass="34747" checksum="910337659DABCE55" modified="2019-04-10" version="1" fragment="single">VGSEDRDSGTESDDEQPYDDPEPGSEMSSEVSSGCSVRSRPTSQTSTDTLTCDDLPMAGDAPDMPPPSTIPSSSVPSSYHHPQHLHHHHHHHLHHSHHPHPGRRARTPRHPHPSLRTPDPPRESPALESPIESFLDSAFVSDCDACDPVEHHSSEEELETLTCSWSRETGPPEKRKWSQVARLSLTDSGSSDEEVCVLTTGSRPPVQFRTSPPLEAHKPLRSVSPPTKMLGLASSGREGLVSASGGGDGRGSPGGGVGGSEGGTPRAEGGARAASPRKRHRHTPRPHQMHRPCLDFEKMQQMKTRAVTQWRNGGELSLSFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M310</accession>
    <name>A0A3R7M310_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002285">
        <property type="protein sequence ID" value="ROT71510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M310"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="467"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="579"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="606"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="638"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="905" mass="99231" checksum="7DCFA4AE62011EBC" modified="2019-04-10" version="1">MLSRRSVRARPFCAATSPIFYSPSGSRGESLWSPLRIAPRTPSSTSNQAVVVGGTARRHGDRAPEFSPPPAASPPLPLLLPLPPFSSSPSPPFSSFSSSFLFSLFLSLLLLLSFLFFSLLLLSFLLSLLPLLLLFFSLFLLFSSSPSSLFSSSSLSPFSSSPLPSSFSSSFLFSLLPPLSLLLPLPPFSSSLSITLSPSFLPFFSLLLSFSIFQFLLYHQYFPVLFSLWLHPSFLLCSSSSSIHLLFSYLLALLKTIGIIIHFLLLLLFLLRFSYSFFSSSISRFFTSSFSPLFLLILSSPPYSFFAFPIPSSPPPSLTSFLLPFPLYFLLILFSPPIPSSLFLFLLLLLHLSLLSFFPFPLYFFLFSSVLLFLLRFSYSFFSSSIFTSFLLPFSPLCLSYSLQSSYFSFAISVATSPFISHFFPSSLFFLFSSVLLFLLSFSHSFFSSSISPFFTSFASSHSSPLPYLFLSLALVKCISILLTITIIIAAIIIILIMLPSPSPASSFSPYLHFYLPSFLSLSSSCSPPPLSLYLLLIPPYILLLLPPPPLCLLFFIFLSIYPFLLIILCPCSSSSLPIFFYFFIHLITIASSLFCLLSFVPGVYIGIIILLLSSLLSITIIASIITILFLHLSSRFLALLLFPPSFFFLVFLLPPLLSFLLLILLLLHPSASSTFSTSSSLSSFSLLPPPPPPPPLPSSLLLLPPLSLPLFFLVPPPLSSSLLFLPLPFLSSPSLLLLLSPSLPPLFPPLPSFLLPLLLPPPFPLLPFPLLPPSSPIPLPPPSSSSPPSPSSSFSPSSFHHLPLPFSFLPPFPPSLLPPSPSPFLPPFFLLPPSPFPLPPPSLLLLSLSPPPFLLLPPPPPSHLLLLPPPCLPALPELTRMRRGLPSRCGSGGELINNGMNKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M792</accession>
    <name>A0A3R7M792_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_012790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002611">
        <property type="protein sequence ID" value="ROT69041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M792"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35193:SF5">
        <property type="entry name" value="FLOCCULATION PROTEIN FLO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35193">
        <property type="entry name" value="MUCIN 13A, CELL SURFACE-ASSOCIATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018703999" evidence="4">
        <location>
            <begin position="27"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="360"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="235"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="477"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT69041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="530" mass="58635" checksum="11719E30CF2193CD" modified="2019-04-10" version="1">MRPKARWGTAVFITLMVVIGTHGTCAQSEDMSEEQLLTEIKRVLENINFSLNELMDVSAATAPSTTTSAATTTAPSTTTSAALPSTTTATTTAHTTAPIHHNFCCYTTASHHNCSPPTAPSTTTALLHTTAPSTTTAPSTTTAPSTTTSAATTTSAATTTAPSTTTSAATTTAPPTTSSPNSPTPVSTTFYRLALGRQRSADDDLCTVTEQNDLCQRLQDVLANIEDSTTEIDSGNVTQQSLERLENDSKELEEVVDEVKNDKDFVYNEAALVEKISKVENTTTEALKHTEDKLAKLHDNGDYTLVIVLGVLGSLVVLSLFAALGFVLYRRNRHRHWFVFICDEIHPGYLNFLLSGQDNTGYQHDEPRTRPPTADPRPHTRRDEKEASTPTASPHRQQSRRPYSAERPTTSLDRRPQYPPAYATAETSSDRNARRPYTSPDRPYTSPDRPYTSPDRPYTSPDRYARQPPAQRGYDSSPDRYGRRKNDPVRRDEDRYDPVRRDEDRYDPYSLDRPGVQKKTYVGKLRRIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAC3</accession>
    <name>A0A3R7MAC3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SPIN-DOC-like zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001542">
        <property type="protein sequence ID" value="ROT77287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAC3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040647">
        <property type="entry name" value="SPIN-DOC_Znf-C2H2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18658">
        <property type="entry name" value="zf-C2H2_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPIN-DOC-like zinc-finger" evidence="2">
        <location>
            <begin position="133"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="42075" checksum="9E41CCC7EC49A974" modified="2019-04-10" version="1" fragment="single">DAGALEDPAVNSDESDTQSAPETPSDLSVMPHPQARTPTPTPANSIPPSSQLTCGAADEPNSSSSACGTPTAPSSAINGSSSAPSVTPPSDAGEEKVTPYFHSILRQVADGGSGGEANTTSAQRVTINMRTFKEEWRRQLLVDYDTRTNMSICMLCFTTFKSYDGPRKNTYVKHAKRFHPSLEEYSEEERDLIISMYEKYHKYDVDMQKEVNKSYSPILTTPPSRAANAIVALGKKGAKHCDIAAVIAGSNGLTGKAGAEVEGHDEGADVVVSEAGVVKEEEAHHAQGKSRSHTPDSEISLEANEKLSDSFDAEEGREKLDNNNITAAQLSKRIPPTLTPTSPSPSTIHPHPPPSPSTPPTLTLHLSTSPSPPPPTSTPPHPASRNLLLSRREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAT1</accession>
    <name>A0A3R7MAT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010034</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002271">
        <property type="protein sequence ID" value="ROT71642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAT1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33416">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33416:SF20">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="505" mass="56957" checksum="ECAE48BCFCA66DCA" modified="2019-04-10" version="1">MRLIRQLPISARHVIIASQSAHVTSSSSPANQRASRHHHRQPISARDVIIIANQSARVTSSSPANQRRSRRFTLSCRLRIAFHITSFYLSVYLHSSFLRFISILPSSLPIFFPYILFLLLSSYFFPSSFLFSFLPSLPIFFPFLLLFLLSFHISSSFFPPIPLLSLLLLFPYISIFFLPLLLFFFSNCSPFFLLLQFFPFLPLPPPLLLNFPPFFLLLLSFFSNFPPFFLLLLLLFFSIAMPDASLCHHLLYLLSLRFFLFFSLLLSFAKSSSFLSSNFSPFLSSFSSSSPISPLSCSSFSSSSPIFPLSSSSSSSSSSQIFPFLPPSSLLLLQFPPFFLLLLLLLFFSIAMPDARLCHHLLYLSFLRFFLFFSFFFSFAKSSSFFPPIFPLSSSSFSSSSENSPFSSLPPFLLFSNFPFSSSSSSSSSSPFSLSSSFFSSSSPISPFLPLLLLLLFFSFAMPDARLCHHLVIEPKVSLATFPSQLCQLANFSNRKSVSDVDMTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBP4</accession>
    <name>A0A3R7MBP4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBP4"/>
    <dbReference type="OrthoDB" id="6350458at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844:SF1">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="414"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="985" mass="110152" checksum="F3126E8FF3B0E7E6" modified="2019-04-10" version="1">MVDTGIDIQDTGGAKREAVREAVNTVAEAVTEAVTEVVKTVMTVSDIKSIDCDRASLTQEAIKDAMNTAAAPAFPAPLMRESCRQDEDLEGECTEVPPEKGQLLSESAADFIDRIKNYMKEQQSDETPNATTVAAEDADDGSALMRLVKIVVEEAAAVLRTVLSWVVPDKMPLQRYDQYLLRDKKMSRASFRSVFNKSHQERLQIDPPGATFDLFLLCLLLEHGTDKLAPSGDEFWVEPGNHLEYQLTALKEFRASVFQGGFVTQKNLTEKAKSAEEILTKILKGAGSISDVEHKVITQKIQEMTENIARAKSDAHVQWSVSSYGEAILSEEKAQLLVFMGSPQLRRSYDNLTCQGLVPVKNINQHLLLEAIFMEVDIAEVTIDGNSKKVDYDDLFNIHSTQQHGTDRPASSQAVLLEGPSGFGKTTLSKKLMLDWSKKANVPRGLDNFALLIHVDCRNPHIKSFSELLKSLMPGARKMFTDDDVVQCLRDIKTLVLVDSLDDLNMSSLQIVREVITAAKSMRNMTVWVLSSPEAAEDFHKTVLSDLSASRLSIMGVPKDRRGELAVRLYKELVQHDCDSQESGGLEAFINATPRLLEEYWRCPLNLVLAASLWVASPESVKSLRSAIDLLVQTDKLCQRDLLEILKETPSTRHFGVSELEDKMKVVFFWLCNEALFAIKRNGRSLAEESVKRLEHACHSVALPSGVVISNFLTKETFLTASGEQSVYSFTHKRLQEFYAAVAILNRLSEKENDVDLTKVLFDLQTVLSSHNISTVRAQEVLRHAHSVLSETSENRKKGLFGKINTVFSSPRETAIVTILREGSHHPPTLPIWRFQNVFAILLSFVSLLGEDIRQDTARELVLLLERTGLRDKESWLDVLMNAGCDPHVAREMARCIPDVLDLDGKITVRDSRVPAYAVLLKYARPSRVKVNISSDPEVIPSCLDLLMSLSQHPCEVQLLLKHDFLHPKVISNVYNVTLHHVFQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC47</accession>
    <name>A0A3R7MC47_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_003409</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001461">
        <property type="protein sequence ID" value="ROT77894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC47"/>
    <dbReference type="OrthoDB" id="6338042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF54">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018544567" description="Carbohydrate sulfotransferase" evidence="10">
        <location>
            <begin position="27"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT77894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="43712" checksum="D0C4F2C4D2DC4291" modified="2019-04-10" version="1">MTLNSRRRTTSSCAVLLVVLFFAVNTYTPDTQRGSSEADLLFPSEAARPVFETLRTKRKLKPESTTSYQSEPTPDLHETFRIRREHLLEQCRRLNITRKFTSEHWLWSMLLEFPGPLDVCLPPKVGSTSWRDLHKRVSERGALPDLHPASAILVRHPLSRLTSAYRDKYLDGAPISDYDKNWRKSQGFNSPRYFYWYNYWLPTLISSGRLAASKEFLKRVRDARSIPGTNSLGIAKLRDAVMDTYGSEDLKTQFSNATFTFREFLEFILWVDELGMRDLHWGTYTEQCLPCQEDYQYILHLETVDAESRVLLQDVGYPEDIRLATKHRTKGLSHSLSTNDLEYYKDLPKALVNKIIKFYEYDFELFGYNKDILTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIN8</accession>
    <name>A0A3R7MIN8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pigment dispersing hormone related peptide 79-penaeid shrimp (Penaeus sp.)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003564">
        <property type="protein sequence ID" value="ROT62688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIN8"/>
    <dbReference type="OrthoDB" id="6378554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="116" mass="13285" checksum="AFAE157AB839C484" modified="2019-04-10" version="1">MSFQHTASGDTLNHFEREIVSELAAQILRVAQGPSAFVAGPHKRNSELINSSWGSQGHERRREEINNECSHLLHTSDHSHDQTRTTKNKNKNFIHHFVVFYHTLLNGRPLRSPSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIP7</accession>
    <name>A0A3R7MIP7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PCI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003718</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001503">
        <property type="protein sequence ID" value="ROT77608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIP7"/>
    <dbReference type="STRING" id="6689.A0A3R7MIP7"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000003">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="189"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="43175" checksum="FF59417DFF9E67BD" modified="2019-04-10" version="1">MEDADEDVAARETGILSLAEQYKKAGQAHQLAQLIKDTRPFLSQISKAKAAKLVRTMVDMFLDMEASTGLEVEVCRENIEWSKSERRTFLRQSLEARLVALFFDTAQYTEALALGSQLLKELKKLDDKNLLVEVQLLESKTYHALGNLPKARAALTSARTTANGIYCPPKLQAALDLQSGILHAAEEKDFKTAFSYFYEAFEGYDSIDSPKALTALKYMLLSKIMLQSPEDVHNIVSGKLALRHSGSHVDAMKGIATASSKRSLADFKTTVAKYKEELEGDMIVKAHLNTLYDNMLEQNLCRIIEPYSKVQVSYVSETIGLPQDAVERKLSQMILDSKLTGILDQGAGVLIVWDPVTKDKTYEHALDTIKAMEKVVDVLYQKAKKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIY4</accession>
    <name>A0A3R7MIY4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_023856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000755">
        <property type="protein sequence ID" value="ROT82955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIY4"/>
    <dbReference type="STRING" id="6689.A0A3R7MIY4"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000006">
        <property type="entry name" value="Aldo-keto reductase family 1 member A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="6">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="34138" checksum="CD6969731EB46364" modified="2019-04-10" version="1">MKKTVTLSCGGHMPLVGLGCWQSPPDQLTRAVEAALDAGYRHIDTAYNYLNEEAVGAGIRNWLEKTGKSRGEVFVVTKLPMNGMYEGGVEKFLKKSLEKLQLGYVDLYLVHGPVGVIGKDDNDIFPMVDGKLNVDFGTDLIAVWKEMEKMKTLGLARSIGVSNFSVKQLRKICAVAKVPPSVQQVELHAYFQQPDMQEFCKSRNIAITAYAPLGSPGRQSIPMLSGGHIPSLMEDPVVRLVAERQGVTAAQVLLRFLVQQGIIAIPKSVTPSRIAANFDVWNFSLTDTEMAALRSLDKGPSGRSFVFANRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ78</accession>
    <name>A0A3R7MJ78_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000726">
        <property type="protein sequence ID" value="ROT83162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ78"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="182" mass="19159" checksum="0D39D2BC14FE8A3B" modified="2019-04-10" version="1">MTSAEDGGPVEGVVEGEEGPRSLPYMSSSAQASPEGMFQKFKKSLSLRLAKKGSRSESPGPGPGSLSAPVGPVPAEPAQPAHLDSQTLPRRRGSVSREDDTKSSFLDYYDYARVYPPIGAASGGRPLPSPRNSAIDISSPVLHLCDFPGITESFFLSRSSVLAHAPPAPTDDVPHALSEETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJE6</accession>
    <name>A0A3R7MJE6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018872</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003467">
        <property type="protein sequence ID" value="ROT63257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJE6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="49744" checksum="8275E0006C2CB16C" modified="2019-04-10" version="1">MLPKNRPRHSVGLSPSGRESARPRRRCPSGRARRAFLRGPAACLPCLPPVVRVALETGSGGDVVRSTPPLSSSSSPSPPLRPHCSTSSPYLFVSLPSLLPPVSPTLLFVVTLFHHPLIPFSSPPSSLFSVIPSPLSFHSLLIISSSAAPPPIPSSPLLLHHPLTSLPFIQYLLFYYPFCFPAPPLSPPSLPLLTQPLKHRLSPLPSLATLPLPLPPQPPSSLSFPHHPLPFPSPLSPSSPVSPSPPPPPPLHFPTIPSPPLSSQPPPLLPHLPLPPPPPSPFPSLPPFHIPIPPPPASPPPHHPPPSSPHPLPPSHHPLPSFAPPSPPLLPHHPPLLPTPPPPPSPPPPPSLPPQPPPHPLLPRHPARPRSPALPWPAVIDSCVIEAVYEELPRVTTTTSNGLIPRSTEMAVMSLLSRPLETSHRRPFPLPRRRTYVLFGFPRRVDFRAAARNLSLCTRHPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJT7</accession>
    <name>A0A3R7MJT7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kni2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023191</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000660">
        <property type="protein sequence ID" value="ROT83623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJT7"/>
    <dbReference type="STRING" id="6689.A0A3R7MJT7"/>
    <dbReference type="OrthoDB" id="6350950at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050200">
        <property type="entry name" value="Nuclear_hormone_rcpt_NR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001628">
        <property type="entry name" value="Znf_hrmn_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48092">
        <property type="entry name" value="KNIRPS-RELATED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00105">
        <property type="entry name" value="zf-C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00399">
        <property type="entry name" value="ZnF_C4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51030">
        <property type="entry name" value="NUCLEAR_REC_DBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Nuclear receptor" evidence="10">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="267"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="487"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="556"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="619" mass="68563" checksum="9050DF7F61466243" modified="2019-04-10" version="1">MAADNNRRDNVTAAAVAADSFFGRTYNNLSQVHECKNGGQCVINKQNRTSCKACRLRKCIMVGMSKSGSRYGRRSNWFKIHCLLQEQAAFNGQTPALRSPITPTLQDGSLPFVSAHLRDSMGRDGPVRAAPQLQGPPELHGQDLQTSLSGLSTRSQLNAQVERRLQEEALSALSRGQGHHPASPDFESHYREQVLEALRRSQNLGSLRRTPDFDALRRSMEIDPLRRTHDLDALDALRQVAPEVEARLGPLAVLEWERRIREVSRRSDTEVTLERKDQLSSEIKGEQLRSPAECCMESASGGSKGGHQSEHEVVSSVKEEILKPEYEQTELALSVHNDVEKSRRETPPKFASEKKGVGILMSEEERLSFLKAVNSQTSVYTRDQAPVTSSARMPTNADLLYNSLNNNIFPFPPYPPLWPSMLPFPPLAKFYPSFGGALPPSAIDGFKSTIYSPLDATSSRSPLRLPKDDAMTKKRFLDAVLQVQRQDSNPHDGGAAGRGLSQAQPSVSPAASPPAPPVTSAAASHDQPMDLTVRRKRKMDKSEIIYNPSDDIADVVESEDEKADEKWLKRTDEEEEPVEEEEEAKASDMIESETQMKPTKAEVPLKLIKLDSPGETLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK68</accession>
    <name>A0A3R7MK68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000465">
        <property type="protein sequence ID" value="ROT84940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK68"/>
    <dbReference type="OrthoDB" id="6375451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018778107" evidence="1">
        <location>
            <begin position="23"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="14735" checksum="3C4DF966F95B4204" modified="2019-04-10" version="1">MAMAKLLSVSLVALVAIVQTSAEPQCYTCMGYNPSLPVDDTQNNPYCVSDSFMASEVPKVNSKHGVCIAETGKNDFTEITIRYGDGGFPRPRNYMYHMGYMCQGNLCNSRPTNSAGTPSLLVPLLLIPAVLPRLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MND4</accession>
    <name>A0A3R7MND4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000936">
        <property type="protein sequence ID" value="ROT81670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MND4"/>
    <dbReference type="STRING" id="6689.A0A3R7MND4"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000040">
        <property type="entry name" value="Tetratricopeptide repeat domain 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000416">
        <property type="entry name" value="Tetratricopeptide repeat protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF108">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="74"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="154"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="394"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="478" mass="53319" checksum="D32A655527A0DBDA" modified="2019-04-10" version="1">MTAVKINTYHWGRRSPTCSRTSRWPSRRDIAGECRAHGNLGSAYFSKGNYKEALTSHRYQLVLAMKCKDTQAAASALTSLGHVYTAIGDYPNALASHKQCVQLVKQMGDKLQEAREIGNVGAVYLAMGDFDSAVDCHMEHLRIAKHLNNKVEEARAYSNLGSSHHYKRNFDQAIAFHNHVLRIAQDLGDRTIEARAYAGLGHAARCMSDYGQAQRWHEKQLDMALSTKDKVAEGRACSNLGIVYQLMGHHDAALKLHQAHLNIARLLQDRAGMGRAYGNIGNAYSAMGYYEQAIKYHKQELTISKEVNDRMSEASTHGNLAVAYQALGMHEMALLHYHSHLNIARELKDTAGEACALLNLGNCHSSRGEFAQAVPYYEQYLMLSQELHDTEGEARACHFLGYAHYCLGNFKEAIRYYDQDLALAKDLQDRKSMGRAYCNLGLAHLALGNSETALECQKYFLGESSWHGSLQGIKSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNX1</accession>
    <name>A0A3R7MNX1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative rho guanine nucleotide exchange factor 10-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000884">
        <property type="protein sequence ID" value="ROT82100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MNX1"/>
    <dbReference type="OrthoDB" id="28697at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051496">
        <property type="term" value="P:positive regulation of stress fiber assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.900.10:FF:000003">
        <property type="entry name" value="Rho guanine nucleotide exchange factor 10 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039919">
        <property type="entry name" value="ARHGEF10/ARHGEF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12877">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12877:SF7">
        <property type="entry name" value="RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 10-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19057">
        <property type="entry name" value="PH_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19056">
        <property type="entry name" value="WD40_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="4">
        <location>
            <begin position="315"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1101"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1286"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="482"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1137"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1177"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1303"/>
            <end position="1334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1384" mass="153501" checksum="42249F8E0813D29F" modified="2019-04-10" version="1">MNKRASADLTNHFGSDVPDRVGGPSRGEGGSGGSSPPTPLYVIYDEPNNSVGVKRNSFRDSRSSRSSRSSRSSTLSGPWCEDRIYEDISDLGSGGGGGGSVGGGSGGGGGGSSGGGGSEETWVSRRLHVHRQLSSSDSWGSEDFESYSSNEEDNGTGSVKNQAPNLENFKQRLLRKREQWRERRQSSKTLKDAIRKDSKEDQPKESAKLVEDNPPSTPDNKLYRWFSLRKSVNYDVERRSSTIANTERTSSYTTTSNGTSTITNHRMPQLLEEGDTEHGGLFSENGGVFAHTFQRRHQPPALPPMPQGLSPEQIKRRHIVASIVHSENNYVATLQRLVNDYKKPLDDSKPPILNAAKLSTLFHRVSEILQCHTLFRIALAESVRQWDREEKIGDVFVASFSKAIVLDIYSDFINNFTRAMEVAKQESKKKTAFADFLKMRQITSPDRLSFFGLMVKPVQRFPQFILFLQDLLKHTPQGHHDRMSLQLALTQLESLAEMLNERKREAEQYQAFRDTLKHINTKFALRGIQEGNRYLLRQDDVLQLEFNQNGLISKSKGRRLFLTNDLIMCVTVVPKTNEDYGQQNERLSLKWAFPVTDVEIQDTSSSPTLSRLLASGVNKTGSINSARIPEETMGSNVDNLCQEMNDLMHDYEIVSRISSLITSLRGTYEGLTSENLQHVASSIQRALHIRDEQMAWVDACCLQFTVKNKDGREKETFTFQTDNPVIKKDWIVELRLAQLALDSANSPAWDVPEQEKRPSTKMPLFVKALPVFSSPHETEVKCGCCYTVTLSRPSRLSGTGRHHNYLWLCSTDGVSSHITIYLMQQVGLREIVRVDLVEVCVTSLQHVPGITTTTDEPSLRAHTVWMGTHSHRLIVYSGLEPERQTELGSTNVPAAVTTIKYHCDQVYVGLCNGCVQVYRRGADGAWQLREPLNIFLGTQGVTALLPINTHVYAACGDHVHVIDCFTAEVTKKFSVHHEGAGGVQLMAHSGIGLWIAQKKTATICLYHTETFRHLQDINVASNVCRVLGDKGPAPSTITVTALLASRGLLWVGTNVGVALTIPLPRLEGVPIISGRANISYHAHRGPITFLLTLQPHARPQATLPELRPGSRPSLQDSHSQSQQESSRIQSSTDDTRSYVSTPTPTSRLEKQQSDGSLIPSRRVPPRLRQQLSSPVILRRKPRDAHQQHVRRLSKTLPRGLGLGTLAGSQECDVYGLYGDLLNVHEYEDEPMVIGEGLLLSRYDSLRRSDPELAVPAQVSTLDRRVRLKASRPRSLDLSTWSVDSRASSACTTSSGSEDGSGGMNSILTATSSTTPCDSGTHASNVGTNSRSATTGRRKEGDPSRTLMTLMGGRGYVNLRHVFEGQQSSHANDRDAHVVVWEMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N6C8</accession>
    <name>A0A3R7N6C8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001377">
        <property type="protein sequence ID" value="ROT78448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2575" mass="287054" checksum="2337BF34D4E1395F" modified="2019-04-10" version="1">MRIIKYEQNFLPSFWQRFTLHSLLGWIRCPLLQVLHHYTASLFTLSWGGYAAPSSGSSSPQRFTLHSLWVDTLPPFFRFHHPQRFTLHSLLGWIRCPLLQVLHHHTASLFTLSWDGYAAPFFRFFITTPLHSSLSLGWITLPLLQVLHHHTASLFTLSWGGYAAPFFRFFITAALHSSLSLGMDTLPPSSGSSSPQRFTLHSLLDGYAAPSSGSSSPQRFTLHSLLGGYAAPFFRFFTLHSSLWGGYAAPFFRFFITAALHSSLSLGVDTLPPSSGSSSQRSLFTLSWGGYAAPSSGSSSPQRFTLHSLLGVDTLPLLQVLHPPSASLFTLSWGGYAAPFFRFFITAALHSSLSLGMDTLPLSSGSSSPQRFTLHSLLGWIRCPFFRFFITHRFTLHSLLGWIRCPFFRFFITTPLHSSLSLGVDTLPLLQVLHHHTASLFTLSWGGYAAPFFRFSSHPALHSSLSLGWIRCPLLQVLHHQRFTLHSLLGWIRCPLLQVLHHHTLHSSLSLGVDTLPPFFRFFTPHAFTLHSLLGGCCPFFSASLFTLSSDGYAAPFFRFFITPALHSSLSLGVDTLPPSSGSSSPQRFTLHSLLGGYAAPFFRFFITSASLFTLSWDGYAAPFFRFFITAALHSSLSLGMDTLPPSSGSSSPQRFTLHSLLGWIRCPLLQVLHHRSASLFTLLGMDTLPLLQVLHHPALHSSLSLGMDTLPLLQVLHHRSASLFTLSWDGYAAPFFRFFITPALHSSLSLGMDTLPPSSGSSSPHRFTLHSLLGWIRCPLLQVLHHRSASLFTLSWDGYAAPFFRFFITQRFTLHSLFGWIRCPFFRFFITTPLHSSLSLGVDTLPLLQVLHHHTASLFTLSWGGYAAPFFRFFITPALHSSLSYWGSLSWIRCPLLQVLHHRSASLFTLSWDGYAAPFFRFFITPALHSSLSLGVDTLPPSSGSSSPQRFTLHSPLGWIRCPLLQVLHPQRFILHSPWMDTLPPSSGSSSPQRFTLHSLLGWIRCPLLQVLHHPSASLFTLSWGGYAAPFFRFFITPALHSSLSLGWIRCPLLQVLHHRSASLFTLSWDGYAAPFFRFFITQRFTLHLSWGGYAAPFFRFFITAALHSSLSLGWIRCPFFRFFITAALHSSLSFGWIRCPFFRFFITQRFTLHSLLGGYAAPFFRFFITAAASLFTLLGWIRCPLLQVLHHPSASLFTLSWDGYAAPFFRFFITQRFTLHSLLGWIRAPFFRFFITQRFTLHSLLGWIRCPFFRFFITQRFTLHSLLGGYAAPFFSSSSPQRFTLHSLLGWIRCPFFRFFITAALHSSLSLGWIRCPFFRFFITAALHLLSLALQVLHHPSASLFTLSWVDTLPPFFRFFITAASLFTLSWVDTPPSSGSSSPQRFTLHSLLDGYAAPFFRFFISLFTLSWGIRCPLLQVLHHRSASLSLSLGMDTLPPSSGSSSPQRFTLHSLWVGYAAPFFRFFITQRFTLHSLLGGYAPPWITALPLFTLSWMDTLPPSSGFFHPQRFTLHSLLGWITLPLLQVLHHRFTLPLLGNGYAAPFFRFFNHPALHSSLSGWIRCPSSGLHHPSASLFTLSWGGLTLPLLQVLITQRFTLHSLLGGYAAPFFRSHHPSASLHSLLGVIRLPPSSGSSSPQRFTLHSLLGWIRCPSFRFFITRSASLSSSLGMDTAAPFRFFITPALHSSLSLGWIRSPFFRFFITAALHSSLSLGMDTLPPSSGSSSPQRFTLHSLFGWIRCPLPPLQVSHHPSASLFTLSSMDTGFSSFLRFFITSSASSFTLSWWISLPFLSGSVITAALHSSLFLGWNTLPPSWFFITPALSSLHSLNWDGLRCALLQVLHHPSASLFTLSWGGYAAPYFKVFITAALLTSHFSLEILSCSSRLSAKHVTLPLSFSASSALSLSLLFPGWIRCPFFFEQLDTPLQASPHTFHSLGWIRCPSQVLHGIRSASLFTLSWVDTLPLLQSTLPGWYAAPFSGSHHRSAHFYSFTSLFGMDTLPPSSVLHTPSASLFTSLWVDTLAPLQVFHHRGSASLFTLSGMDTAPPSSGSYMLPALSLSLSLGMERCPLLQRSSSPSASSHFSWRWIRCPLLQVLQSRSALHSSLSLGMDTLPPSQVLHHPSASLFTLSWLIRCPLFRYFITASASLFTLLGMDTLPPSSGSSSPQRFTLHSPSMDTLPPSSGFSHRSASLSLSLGVDTPPLLQRFTLHSPWMVRCPLLQVLHHRSASLSLSLGVDTLPLLQVLHHRSASLFTLSLRMDTACPSSGSSSPSRFTLHSLLDGYACPLLSVLHHAHASLFTLFGMDTLPFFRFFITTQRFTLHSLLDDTLPPSSGSSSPHRFTLTLPSMNTLPPSSGSSSPQRFTLHSLLGGYAAPLLQVLHHRSASLFTLSSDGIRCPFFRFFHHHSASLFPLFGWIRCPFFSSLFTLSWDGYAAPFFRFFITAALHSSLSLGVDTLPLLQVLHPPSASLFTLSWGGYAAPFFRFFITAALHSSLSLRMDTLPPSSGSSSPQRFTLHSLLGDTLPPSSGSSSPQRFTLHSLLGWIRCPLLQVLHHPSASLFTLSWGGYAAPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N6R2</accession>
    <name>A0A3R7N6R2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001342">
        <property type="protein sequence ID" value="ROT78734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N6R2"/>
    <dbReference type="OrthoDB" id="6351668at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018740772" evidence="3">
        <location>
            <begin position="18"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="45084" checksum="BC90D61B884B4944" modified="2019-04-10" version="1">MLLGVLCVITGIGVAEATVDLTRESQDCEVLQLPLGHPMKVFAETLQVAVFLLDGSMTAAAAAISDAAGHKCIIHIQTDAENETLADVNITCSNNSTASSRIANAFRPEKWTELFISVEDKTQHDRLNDTDGDDSYDILVMVRREKERDFFLKIFPSGLKPPLRMRWLSHNNMSLVFNCGKGEGCQLHNAASTTGVAELVLYFQPASSPAAMDIEVNLTPSETLTIPLRQELPNTKGWKAVQLTRDRNAINVWVDNQKVKRVYTRVTFPDNDILDVNLKGSGQMMTWCDPRPAAESTGVPTSALTSTALFDFLPWILAAVFLLVSVVVTVFLIRSRRSLSRTKRALRAQESPATPSDSSIVQMPHDLQLLPSTSSSMRSFGAPSRVRNSDRLSQLSYDNPMPHVMHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NV11</accession>
    <name>A0A3R7NV11_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014491</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002809">
        <property type="protein sequence ID" value="ROT67447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NV11"/>
    <dbReference type="STRING" id="6689.A0A3R7NV11"/>
    <dbReference type="OrthoDB" id="9979394at2759"/>
    <dbReference type="UniPathway" id="UPA00230"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047620">
        <property type="term" value="F:acylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001729">
        <property type="term" value="F:ceramide kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046486">
        <property type="term" value="P:glycerolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="297" mass="33015" checksum="C10B54B54D44B795" modified="2019-04-10" version="1">MGVMENTSAVVVAGGDGTLAEVLTGLLRRADHEEAASRLPLGVLPLGKTNCATSAIWGFRGNPEPRHLAEAAMAVIRDIKRPLDVMEITPLQGGEEGVPPKPVFAASKVEWGAYRDARERNDVYWYWSVLKKYMTYVFSSYKDISWDCSADIEYSTPCSGCSRCRGTVKEEHKVEETPKPPQRWWMAYLPRTKPVSTPKEEKKIDYSSIINEECGVVKKTTVSDISDLSVVTRNTPESLDIPNYALALKTGPTNVGSFAFIQEGWSREWNKSNSYDAESIIGEITLTPTGNTKTNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3D4</accession>
    <name>A0A3R7P3D4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Battenin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_007179</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Lysosome membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the battenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001910">
        <property type="protein sequence ID" value="ROT74327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3D4"/>
    <dbReference type="STRING" id="6689.A0A3R7P3D4"/>
    <dbReference type="OrthoDB" id="5965864at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007040">
        <property type="term" value="P:lysosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003492">
        <property type="entry name" value="Battenin_disease_Cln3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018460">
        <property type="entry name" value="Battenin_disease_Cln3_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10981:SF0">
        <property type="entry name" value="BATTENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02487">
        <property type="entry name" value="CLN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015974">
        <property type="entry name" value="CLN3_BTN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01315">
        <property type="entry name" value="BATTENIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT74327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="449" mass="50105" checksum="2EE85CD354E42686" modified="2019-04-10" version="1">MSHSFDVVDTSVDTDEYESAMDSTPIQSFSTTEGMISVTEPAPSSDIVKERWTNLLAYWLLGLTNNFAYVVMLSAAHDILSQDFSKDAVGLPENATNISNPRDCNRMSTGAILLADIIPSLIMKVFAPFMWSHIHFRVGTVVMLCVLSFVLVGEAVSENMAIIGVVCASASSGLGEVTFLAYTARFHRNVVSTWSSGTGAAGLFGALSYAGFTSAGLTPRTTVLLMLIIPVVMSLSFWLLLKHPNQAGLCGSRQHYKIIRQEEDDESIEAKDFEVSLRFSEKMELLPSLLKYMIPIALVYIAEYVINQGLVELIYFPDQKDWLNHHEQYRWYQATYQLGVLLSRSSVNFFYIRQVWITTVLQWINVLIFLTCAVFWWISSIWVVLVLILWEGLLGGAAYVNTFYKITQEVSDHQKPFALAITTLSDTVGVTIAGFISIPLHNVICQLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6X7</accession>
    <name>A0A3R7P6X7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_019446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003563">
        <property type="protein sequence ID" value="ROT62690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6X7"/>
    <dbReference type="STRING" id="6689.A0A3R7P6X7"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF79">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT62690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31762" checksum="225D928F4AFB002D" modified="2019-04-10" version="1">MHSDRTICNRGGRRWHWMRSWTLWKHYRDFFPVHLIKTAELDPSKNYIMGYHPHGILSAGAFCHFATEGTDFSKRFQGFTPFLLTLEAQFWLPLYREFFMCTGAVSATRESMDYLLGREGSGRALCLVVGGAKEALDCHPGQVILHLSKRKGFCKMALRHGASLVPMFSFGENDVYDQIANPEGSLIRRIQNSVQKMIGLAPCMFIGRGVFQYSFGIVPFRKPIYTVVGAPIDVPLVKNPTKEQIVKLHETYVNAVVDLYNKYKDRYSEHPECKISIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P954</accession>
    <name>A0A3R7P954_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein D-ETS-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_002347</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ETS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P954"/>
    <dbReference type="STRING" id="6689.A0A3R7P954"/>
    <dbReference type="OrthoDB" id="10067219at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000039">
        <property type="entry name" value="Friend leukemia integration 1 transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000418">
        <property type="entry name" value="Ets_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046328">
        <property type="entry name" value="ETS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849:SF304">
        <property type="entry name" value="DNA-BINDING PROTEIN D-ETS-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11849">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00178">
        <property type="entry name" value="Ets"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00454">
        <property type="entry name" value="ETSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00413">
        <property type="entry name" value="ETS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00345">
        <property type="entry name" value="ETS_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50061">
        <property type="entry name" value="ETS_DOMAIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETS" evidence="7">
        <location>
            <begin position="63"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT78951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13557" checksum="0C07045C041A3D94" modified="2019-04-10" version="1" fragment="single">PSYKSAWGSPASPASQTQGYPHNTLGMTKSSLDAHSPHLRQPDPYQMFGPTSSRLASSGSGQIQLWQFLLELLSDSSNANCITWEGTNGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAQ4</accession>
    <name>A0A3R7PAQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000944</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001130">
        <property type="protein sequence ID" value="ROT80327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PAQ4"/>
    <dbReference type="OrthoDB" id="6376680at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1373"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="952"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="974"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1486" mass="159149" checksum="45CF0B1855F933C3" modified="2019-04-10" version="1">MASSAGTQGPRIPPQGAPGSQRGHEGHQEGVEVLRIPAQASTFEGVEATPQALPEDSTPLPAKGDAEAFLTEDPRLLRPSLPTEQQPMHEAGAVNRRGWLAEDLAGTRYGVLQEDESTQRINALSTEDVTDTDYYWDSHGDAEDLDRLETSELRPEHQRDPEERWPFPSDNYRAGPPESPRYPPEVAQVVPEPTVQQRYAEQRQLLTHYLKEYLNELTRSPDSHLVVQQLMQQQPQAQELMQQWLQEQRLLYSQGPQAVLGIPREPNLPGGLFPHLPGQQSHLQKLVEQYQRLQKQTSSDTQAPSQAAGQLPLSQPPAVADSQLNLSSDVDTFNIVITKNLTGGQSQPSVQYLPDAQVDALLLNTSITSVSNISSLRDVVNNAISAAVANNPVAIQEAIAQVVERPGHEPTVNVINSTMSTLGEVESALSTLLGSTVVYEENPAANTAVGYIPRPDSSVGSQPPPPPAPLPSALAPLQPAPAPLHALQPAPAPPAISSFHVVSAIPAPSLAGPQEVPAGYVPTNLAGPSHAASLAGRPRPPGALPQGPFPPNPQTVLPPAPPMAVLPPAIPLPGSPIPPLGAAGQGEPQAGSSGGARPGASRPENPDGINLNNNEVLQLLPDFVRATTIPPVVPLYNTSAHQLLEQNPSVLGLLPNQVFEITKPKFHFDNSTTGGIIRKVPVGNLTEFFPPKRAPTQAQRTPQPSSPAFQGNRYQYQSYETSAVPNRPLPFESSLLQNYPRLPDQGSPFYYSAGGDTPTSRLPARHQNPAQAYNVVSQAQAELSNFANLLQLTSNDTNAENEESALPNYANLRTETSGPSQRFGFTEDTDVTQDTKEDVTKTEQMIATSTAVAADPASAAEPKSRLQMDNLMKAVAIGALPSSIAFATALWPYWAPLLLGRRRKRDASALGDPADRARISNDWLSILTGAKYKEAGADFPSAWDRLALRKNNQKNSAAPTRIAAEEASRPTPAGESSSSIPGDDSPSEAPSEAPPSTDRAATGPPEEAPAPEGSAAALADSESENILRTTEKATTVKRATPAGPPLTTTGKGMEQSVAQVISSLSPTGSAPFTVEAQTEAGAEQQKEDDAPADVALVTNFLYSTLNDWNRESPTTRNDPPAEEEQPAVKDLIELDISTGAPTQRGQREAGDDAPDGGGDGVLHVPASTRAHDREDDSSCVVFVYFVDFIDCSIIFGINYNISDSNDNSINVSVNFSTNVNLDAGNNVSLDVGNNVSLDVGNNVSLDVGNNVSLDVCPNVGLDISTNVSVNLNLDISSNVSRDVSLDHQRPRETEAELDDLAAGRVHQQPAGDHGRPGGGLRLHVQPGARADPVVVDAACELWRPHPYLAPGIFDSIATVLADEDGQLQSAVSFVGSVAVYGAAALMPLWLPIVLGKRRRRRDLQLEDDLQDILEAVRMIHSPLPVARSLEFGDSEEGKKPLRRRDRAAGAEADEEAINIYEQFPLLRHFVEFLKEELKNRAKLKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAV1</accession>
    <name>A0A3R7PAV1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_016530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003081">
        <property type="protein sequence ID" value="ROT65499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAV1"/>
    <dbReference type="OrthoDB" id="6359168at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="6">
        <location>
            <begin position="33"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT65499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="313" mass="35673" checksum="FE7F0934144FE477" modified="2019-04-10" version="1">MNIANCSVEASVWRWRTWALGVELTTCVLGAVGCVIGFCCLRACEKIKVGMKIQISLIFTVSFIVCTVALPGYAIADYWTICWQIKGTSVLAFLIFYSVSVNIVRNYFTVLAIYRFLAVCFPIRYQQFSQRRVVTGIVVTVTVCIVLAWSTLYIIQDYSNVDVNNRSSYYLGRILFYFSLVIPFTVTVIAYFALALFVIYRKLFITQPQGIHRRDQIAESVSILILMNLLLDVPHITVHLSDTSSNDVSYIIVHMIYHLRFVFDSFLFVCLNKRYRLMVLRYVSSKLLRRELADITFSDTPSVPSAGSVGPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAX5</accession>
    <name>A0A3R7PAX5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative hfb2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BZW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003069">
        <property type="protein sequence ID" value="ROT65566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAX5"/>
    <dbReference type="STRING" id="6689.A0A3R7PAX5"/>
    <dbReference type="OrthoDB" id="1727522at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11560">
        <property type="entry name" value="W2_eIF5C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000006">
        <property type="entry name" value="Basic leucine zipper and W2 domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051245">
        <property type="entry name" value="eIF5-mimic_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057397">
        <property type="entry name" value="HEAT_5MP1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043510">
        <property type="entry name" value="W2_5MP1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208">
        <property type="entry name" value="BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208:SF2">
        <property type="entry name" value="PROTEIN KRASAVIETZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25504">
        <property type="entry name" value="HEAT_5MP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="3">
        <location>
            <begin position="303"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="476" mass="54280" checksum="2B625B4A0C9BC62D" modified="2019-04-10" version="1">MKYSRKGYRPLSAAGESRGPGCSSVHFHALFSRSSCKGFLSLVLFIFFVCCMTTKAEKPTLQGQRIKTRKRDEKAKYDPVGFRDAILQGLNESGTDLEAVNKYLDQAGSKLKYRTYGETLFDILIAGGILTPGGGISEDGIDQGPVRTDMCIFKAPDDSYETLRGYATVFTRLMRRYKYLEKMFYEEMKKVLVYLKGFTEGDRIRLARCIAMWMSDSLLDPKVLATLLQDHLIKDGLAADFLCEVLLTAKNLKDISTVRSLLRKAGLDSRLMEFLQANKRTDENFKNLFQEKGLAEILDIHRSLEKESSLKELQIYLTQQVNEGAPVKEIIIGVQEISKKNNIQEPQVVAAIWGSVMAAMEWNKKEELVADQALKHLRVYAPLFAANTRSDRAELNLLVRVQEYCYDNMNFMKVFHKIVILFYKSEVLSEEAVLKWYKDGHATKGKSIFLDQLKKFVEWLQNAEEESDESGDEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBW1</accession>
    <name>A0A3R7PBW1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002975">
        <property type="protein sequence ID" value="ROT66218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBW1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="13962" checksum="0B77BD6A66C0A3CE" modified="2019-04-10" version="1" fragment="single">MLNKARGNVDKKTGIFRQGSMGQEPGGHTNSLGSGLNTHMTPDKLGPLGNSQPWPSPATQGPTNTTQGLPHSTSPHAGNKGPTNTPDVDLSQLSEEERAIIESVMAKAQEMETHDTPAKRSADEAQRLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCB5</accession>
    <name>A0A3R7PCB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative serine/arginine-rich splicing factor 7-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_025132</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000931">
        <property type="protein sequence ID" value="ROT81713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCB5"/>
    <dbReference type="STRING" id="6689.A0A3R7PCB5"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000899">
        <property type="entry name" value="RNA-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF3">
        <property type="entry name" value="SPLICING FACTOR, ARGININE_SERINE-RICH 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="128"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT81713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="356" mass="41158" checksum="39108AE480054E23" modified="2019-04-10" version="1">MKSSFAAHVVAERRSWELGEDARSLVRRRNSVYFFSSRSPVLEAKSAVERHVRPREGFGGEFHGFSSSLNPEGDGSASPTHAGYRWADSAFTHGLHAISTQAKIKSSIPCVGEREVVRGPKMPSTLDCKVYVGDLGSGASKQELEEAFSYYGPLRNVWVARNPPGFAFVEFEDMRDAEDAVRGLDGRTICGRRVRVELSTGKSRSRFRGPPPRRGRPFHPDDRCYECGERGHYARDCHRYSRRYGSRSRSRSRTPRRRRSYTRSRSRTRDRSRSRTRDRSRSRDRSRSRDRSRSRSRTRDRSRTRERSRSRSISRDRDRDRERSLSRDDKGTFRDRSRSRTPQQNGSPKVDDGKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCE1</accession>
    <name>A0A3R7PCE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_015389</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCE1"/>
    <dbReference type="OrthoDB" id="6332316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="16">
        <location>
            <begin position="70"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT66590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="42390" checksum="3E58285390B81CBD" modified="2019-04-10" version="1">MSFWSEPANVAPNSLPSTNPYGNYTVVDTVPKEILHMVDSHWYQFPPMNPLWYSLVGFWMVIMGLLSVFGNFVVLWVFMTTKSLRSPANTLVVNLALSDFLMMFTMFPPMVISCYWQTWTLGAFFCEIYAFLGSLFGCVSIWTMVFITADRYNVIVKGVAGDPLSSKDASLRIVFTWIVSFAWCLPPFFGWNRYVPEGNMTACGTDYLSGDMFSNSYLYIYSIWVYIFPLLYIIYSYTFIVKAVANHEKQMREQAKKMGVKSLRSDEAQKTSAECRLAKVALMTVTLWFMAWTPYFVINYGGMLNKSMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPFLACATEGKDNISESVSTNEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEV1</accession>
    <name>A0A3R7PEV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tripartite motif-containing protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022571</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000577">
        <property type="protein sequence ID" value="ROT84239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEV1"/>
    <dbReference type="OrthoDB" id="295536at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF15">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="247"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="363"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="395"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="42988" checksum="33596604FCA9F96D" modified="2019-04-10" version="1">MRGSCLGVGGGPAVWRHVRATKRSCRLAGGLVRGGGESAPEPAAVVNRQGFSVAPTIRSVQALLAEPVGGQQAGPPGHDPDPPDGGADSDKASVYSETDSGVVVASRPTSYVSSPETTVNNEGGDGQPAAGQQQGVRCPVCHKVSALGPGAAADLPRYTAMSRIIARQRGDPSLGEASASTSAPTGTPATLPPCQLCEGPPRAATTECQQCQVLYCGPCLTSCHPPRGPLATHTLGSVAPLGGSIPGAGEVCAAHGERPSLYCLVCRWSGCRECGPGHSQHDLQPLDNLAKTHKVSVAALLYSHALRFFLSSLASTLPHSPFTLAYYDHLAPHITTASYDITTTTHHLLRPPRTTYNLHAAHHRNPDHSTLSCAPPPLRHHPTPALTAHAAPPTSSGRENPSSTSSSPCRGRRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIG9</accession>
    <name>A0A3R7PIG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014263</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002785">
        <property type="protein sequence ID" value="ROT67641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIG9"/>
    <dbReference type="STRING" id="6689.A0A3R7PIG9"/>
    <dbReference type="OrthoDB" id="6369165at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000008">
        <property type="entry name" value="Chitinase 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF360">
        <property type="entry name" value="CHITINASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018542377" evidence="2">
        <location>
            <begin position="24"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="23"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="50452" checksum="3FE44658EB22B9FA" modified="2019-04-10" version="1">MRTLVVATFFVLAGLCLSGTAEAVTICYFGSWAVWRQGAGRYDVGDIDPFLCTHLIYGFAEISTATWEVEAMEPYNDLCVDYGQCAYSRFTALKNLNPDLKTILSVGGNSVEGSTFSQLSEDASRRKIFVNSAVEMLKNYSFDGLDINWMHPTGEGGQPEDKENYIALLRDLHGALADEDLLLTACVSLKKPVVDVAYDVPELSDVVDFVMLNGYNLHGPWHTFTHHHAPLFAHPADTGANALLSIDYGVRYWISKGVDKTKLVLGLSTYGTTWTLNSLGDTGYYAYATQAGKPGPYTATLGILGYNEICELQHGSDQWTVVRDPAMHEPYAYSTTDKTWCGYEDSQSLWRKYARSQGLAGVMVWSSLETGRLLGVLQRGGPTLIRSMTEGFLDLPFSTPVSHCEAAPRTTRECPEGLVWNTRPGRVHLALRHRHRALPHARPDDDTAGDSYSNCGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PII9</accession>
    <name>A0A3R7PII9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative cytosolic non-specific dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002776">
        <property type="protein sequence ID" value="ROT67696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PII9"/>
    <dbReference type="STRING" id="6689.A0A3R7PII9"/>
    <dbReference type="OrthoDB" id="7832001at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05676">
        <property type="entry name" value="M20_dipept_like_CNDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000014">
        <property type="entry name" value="Cytosolic non-specific dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017153">
        <property type="entry name" value="CNDP/DUG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051458">
        <property type="entry name" value="Cyt/Met_Dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270">
        <property type="entry name" value="BETA-ALA-HIS DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43270:SF4">
        <property type="entry name" value="CARNOSINE DIPEPTIDASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037242">
        <property type="entry name" value="CNDP_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="10">
        <location>
            <begin position="211"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="7">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between homodimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="9">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037242-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="53270" checksum="48B2A90FF0FEFDFD" modified="2019-04-10" version="1">MAVPENLTKIFKYVDDNKARFIDVLREAVAIKSVSAWAETRGEIKKQMEWAKAKLEALGASCELHDIGQQTLPNGTKIPLPPVLFGQLGTDPKKKTVCVYGHLDVQPALKEDGWDTEPFVLTEKDGKLYGRGSTDDKGPVIGWIHAIEAFQKTGQEIPVNVKFVFEGMEESGSEGLEELLKAQKDKFLKGTDFVCISDNYWLGKKKPCITYGLRGICYYCIEVECCDKDLHSGVFGGTVHEGMADLIYLMNTLLDSKGNILVPGIMNEVAPVTPEEEALYKDIDFDVEDYRKDLGHERLVHHNDKTKTLMARWRNPSLSLHGIEGAFSEPGAKTVIPRKVIGKFSIRIVPNQTPESVSKLVIDYLNKQWEARHSPNKMKAFFFHGGRCWMSDTTHPNYEAGRRATKYVYGVEPDLTREGGSIPVTLVLQEVTGKNVMLLPMGACDDGAHSQNEKINITNYIEGTKLLAAYLNEVGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIY9</accession>
    <name>A0A3R7PIY9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative xanthine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002031">
        <property type="protein sequence ID" value="ROT73358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIY9"/>
    <dbReference type="STRING" id="6689.A0A3R7PIY9"/>
    <dbReference type="OrthoDB" id="8300278at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="CO dehydrogenase ISP C-domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="[2Fe-2S]-binding" evidence="1">
        <location>
            <begin position="34"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="132" mass="14255" checksum="AD69A3D09137C259" modified="2019-04-10" version="1">MISRYDREADKVEHYSINACLAPVVSLHGLAVTTVEGIGSTRTGLHAVQERIALAHGSQCGFCTPGMVMSMYTLLRNKPRPSMADLDEYFAGNLCRCTGYRPIIEGFRSFTTDAGAGGSCGRSDCCRRKGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJK6</accession>
    <name>A0A3R7PJK6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007583</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001962">
        <property type="protein sequence ID" value="ROT73940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJK6"/>
    <dbReference type="OrthoDB" id="6376410at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="509"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="797"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="799"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="838" mass="93863" checksum="5FDCB7634FDC711F" modified="2019-04-10" version="1">MGRRNGGSRNNSPSRPSTSQEAASAPSVGRNSPSGQTLLPDSDDRGIERLPEISVMEELFQKISQLTLEVQNLRFQNSELEARISRPSTPVSVREAPPVEFVVQRDPIPQFKAEVSSAHPLKRNQEVESWLRSVENHTRPQTDAAFIKAAKASCRLSDHGFFAAAEVDPPRKYCRYHKNHEHDSSECRVLSERRKCLHVVSKVTLHGSVPLYRARSGVAATPSLASKEVLSTTDCDNEVLQKPAGRPMVSLMVNGFKTQCFVDTGSEVAHVAVPAFVPPRSGRFVKCSVPRGMQAAKELMVSGIECPLVVPRSLQESGSSTDCPEDVQLKDAELGDLLSEIDLGHLTLEQQQQLRQVLVKYVALFDAQVAATELHNRDPDDLRRHQLEDPLWKEVIEYLEERNLPRRRLPLTLEEFELRDGVLYHVRHLPDRVLHQLVVPKTLRGSAMHLAHSSATAGHPGVYRTYCKLRDYFYFPNMLAAVKEYVGTCRSCQKRKGMAYRAPLAAAPQASYPLERVSADLMELEVTSQGNRYVLAFIDQLTRYVQLIPLPSKDAETVADAFINQFVTVFGPPRLLQTDNGREFKNNLFKRVCELASVQTIFTTAFHPQANGMIERTNRVVKNALATLLEASPLEWDELLPYVRLAMNSAVHRSVGDQPLYLLTGHIGTYPVGNSNYEETDHEAAQSFAARLRRAREIAVETSVQAREGWARDYNRRTRKSTFAAEVGDLVLFKDLPRMAGAGRRGALGPRWFGPARICKKTGPVTRLVRVLSPPYKEKIYHLNQLRPYRTNDELHLPDEDELNEDGDVDDPPPLDGLPEDDPAVALLASFCRPPDHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PP12</accession>
    <name>A0A3R7PP12_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_008996</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PP12"/>
    <dbReference type="STRING" id="6689.A0A3R7PP12"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090433">
        <property type="term" value="F:palmitoyl-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT72635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="551" mass="60152" checksum="9C1E400CE7B38ADC" modified="2019-04-10" version="1">MFAETRAEWFMAAMGCLRQRLSLVTVYTNLAETTSCRLVERETEVSVVITSYDLLARTLKLLPKCTAIKHVIVMEDQLEGLGRNSARKTSKGRGCVMAFKDVGESWGAWKPPRTCHCDDLAIIMYTSGSGGRPKGVELTQHKTSSSANHGATPSRPTFGLVTLATEISLVAMNVTIVYSSPLTLTSVSPKIMKGTLGDAQVAKPTCLNAVPLVLDRIINQSNEDQGYLKAKIFNTALKLKQTVPPSVSKLFDALIFNKVKEHLGGELRMLVVGGAPLSPETHTKIRAMFGCTVQVGYGATETAASISSTDTDDTRTGQCGPPNHGVLVTLRDWEEGGYRATDEPHPRGEILVGGPTVSRGYFRLPAETEESFIEKDGQRWFQTGDIGEFDDTGVLRIIDRKKDLVKLRTGEYISLGAIEMKLKTHPVIESIFVWAFPGAENCLAIAVPIQDRLRKISDNLDPKADPKGEITFANLCKEKAVVAAVLKELQSHGKKQGLGRWDLPVGLHLSPEPWTPESGLVTAALKIRRKPLVAHFKSDIDALYGNLGSQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQ76</accession>
    <name>A0A3R7PQ76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002005">
        <property type="protein sequence ID" value="ROT73686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQ76"/>
    <dbReference type="OrthoDB" id="6366770at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="103"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="40565" checksum="0BEBE3BF0C425E1B" modified="2019-04-10" version="1">MKPPVEVVAVRERQRPEEDRRKSHDLPDGGAAGGADEGNERRSSVVILDRPNSLVEKEVDDASVNSSLLSALSSSPKSKRTASRTAGRAMGYTMNLSGKFVTELTLFDPSEGPVRTSHINLGVFLATDQAMGDHSIYKVSPVSPLAMLKIKTQDRLVRLNDVSVEGWSHSSVVDFVRNLTLADNEYRRAGKMVRSTDEAPTRATVDSVKESEVRVRHDSEHVMRLRLKHDLPLYVKVTTRSNGVMNLGTGETDAHDETVCFTLHLFTASPPYAEGGQVVVLETGNAAGLVYANSPASIGVLQGTTVPVAAHTQVDIKFFLLHGAVGSPFVSLRNLLTGNYLSASQEGLRLVRHDINKLLPDSCLFQVHHCQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRZ9</accession>
    <name>A0A3R7PRZ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001808">
        <property type="protein sequence ID" value="ROT75127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRZ9"/>
    <dbReference type="STRING" id="6689.A0A3R7PRZ9"/>
    <dbReference type="OrthoDB" id="6376275at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="514" mass="56917" checksum="798B6CC78AC6057B" modified="2019-04-10" version="1">MVLTLPRTREDWPVFSSSCLYKRTHADRRIPPLLPPSLTLSSTHLLTPTFLTPASSPRVLHSPIHLLFDPTNNSNQGHSDEANNETREGLGIFLSAGHGGGGTGLFLTYISAIITGVEAGVFAILNIVLLSMHSCTEEPPEKLGGGLDTFWDWYFYDEQKCQLQHENYTAPSWINATQYPLDSRPRTTMEENIKYQITYLALHSAWLLSCLLLIYGNARKLWANPVRFQEQQRHESPPHPPTQLPPHPHHPPILNNPPPSLLITPPPHPHPPPPSLPPSLTHPHPHHPLFTHTPPSLSSPANPVRFQEQQRMISPYHPPPPSPPPQSSSSTPHPPPHHQPPHHPLITPLTPLTHPPPHPTTPSPPSPLSLTPPSLSSPANPVRFKSSSSMISPHHPHHHPPPPPHHPSPPLTPPHHPHPPLTPTLPSSPLTHQPLPPPHSPLTHPHHHPPSLPHLSSPPQQIPFGFKSSSGMIWAFSMYLRGYVIWLVNLVEFGTGLNAFSKTQSDMLIVINRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWI0</accession>
    <name>A0A3R7PWI0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000470">
        <property type="protein sequence ID" value="ROT84923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWI0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="531" mass="59944" checksum="34A65EE38E16A125" modified="2019-04-10" version="1">MCTEEPRSSPPSRPKGTRRPRVAPVTPEGYTETQEVAPVTPEGDTESQEFAPVTPEGDTETQEVAPVTPSRQHGDPGGRPRHARRGHGDPGGRPRHARRGHGDPGGRPRHARRGHGRDPEGRPRHARRGHGVPGVAPSRPKDAEEVSRRRDMEGRSPPHARRSRFAPVTPEGRDQEVAPSRPKDTETQEVAPVTPEGTWRDPEGRPVTPEGDMKRPRSRPVTPEGDMEETQEVAPVTPEGTRIPGAPPSRPKGTWKRQESPPSRRRTRRPRRSPPSRPKGTWKRPRRSPPSRPKGTWKRPRRSPPSGRRDRETGRPCHEDRRPWVAPSPEGDRETLSRPCHEPWKRRPPSRPKGHGRDPEGRPRHARRRQETLRPCHARRERPRRSPPSRPKGTWKEPEGRPRHARRGHGVPGGRPRHARRRQGDPGGRPCHARRGHGRPSRPRGPTRSRPVTRRGHAQRSPRHARRDTERPRRSPPSRPKGHGDPERSPPSRPKGRPREPTLEVAPVTPEGDTEETQEVAPVMFDTALFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWP4</accession>
    <name>A0A3R7PWP4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003951">
        <property type="protein sequence ID" value="ROT61886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWP4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="43305" checksum="6501122810A59783" modified="2019-04-10" version="1">MRHNADQSTRPPRPGSLSPSPLLFPPKRFLSNRTNETLIQLFPQNVSCHNRIEPDQLFPPTLLVHRTNETLISCFLPKRSCRNRTNETLISCFLPNASCPTRTTKTPLISLFFLPNASVPNRTNETLISCFLPKRFLSQPHERNPDQLFPPKTFLVPTARTRNPDQPVSSQNASCQTGRTLISCFLPKRFLSQTTLHERNPDQLFSQNAFCHNHERNLISVSSQNASCHNRTNETLISCFLPKRFLSTTARNETLISCFLPKRFLSQPHERNPDQLFPPKTLLVTTARNPDQLFPPKTLLCQQPHERTLISCSSKTLLVTTARTKPDQLFPPKSSLSKPHERNPDQLFPPKRLPVTTARNETDQLFPPKTLLVTTARTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZC6</accession>
    <name>A0A3R7PZC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003268">
        <property type="protein sequence ID" value="ROT64328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZC6"/>
    <dbReference type="STRING" id="6689.A0A3R7PZC6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="456" mass="50138" checksum="8F8464DB6327328B" modified="2019-04-10" version="1">MLGISLTLTFSPIPTHILSLSLTSSPSHTHPLTFSPSHSHSHPPTHLLIHTHSPSHPYPLTFSPSHSHSHLLHPPTHLLTHTTHFLTSPLTFSPTPTHLLTHTHTHTHTSPHHTHSLTFSPSHSHSHPPTHLLTHNPLTFSPSHSHSHLLTPTHSPSHPHPLTFSPTPTHLLSLSLTFSPTHSPSHPHPLTFSPTPTHFLTHTHSPSLPLTSPTHSHSHPHTHISHSHTHILTSPSLTHTHSPSLTHSPSPHLLTHTHSPSHPHPLTFSPTPTHLSHHTHSILIPHPLTSHPHPLHLLIHTHSPSHPHPTSPSHPHTHILTLTLTFSPTHSPSHPHPLTFSPIPTHLLTHTHSPSHPHPLTFSPPHLHTPLTFSPTPTSPSHPYPLTFSPHPLTFSPTPTHLLIHTLTFSPTPTHPLTPTHLLIHTLTFSPTPTHLLTLTHSPTPSPSPTHIHSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q176</accession>
    <name>A0A3R7Q176_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000700">
        <property type="protein sequence ID" value="ROT83320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q176"/>
    <dbReference type="SMR" id="A0A3R7Q176"/>
    <dbReference type="OrthoDB" id="10040891at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50270">
        <property type="entry name" value="NGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="331" mass="37729" checksum="7A072DAA127820A0" modified="2019-04-10" version="1">MYIYIPGRAHPWRKPVQDIRYQTRYGNIENGQETRQHGKVSSIHKHHRTQGQPADVEALLKETLMELLEDAAERRLPPPLETNELEDIGIDAEQAALYSARHADIEDRPRDHSRQRHPSTSYQIHHEEVCKTVKTWKLINETVDVDGNKVVIVNPIEPKQYVYSYECVSPCTACKGVMGQSMCKMRYSYVKMYHRKCSNNSMRDDGAEWGFVQVPSHCACELIPDNTNDKEYWLCQHPAFLRETAGPHAASFIPTWPSEKARLPYIVLQDLGASHSCPTHLCRSPRSPCTALHDLQVDRGRPPGAPRPLCVDPRGAVASKSLFIKTLATRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q557</accession>
    <name>A0A3R7Q557_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002626">
        <property type="protein sequence ID" value="ROT68866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q557"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="30658" checksum="73C0655C291CF2B8" modified="2019-04-10" version="1">MIEKNLKNLNPETVETKTSGRKSHLRVTVAIEISESSSHESQKDVDLEETEMTALEGIVRTAEVLDETEMNVGSEETGKSVEVLEEIVRSVEALEETVMTGTVQVTGVVDHQGLIVTSAVVTETGTLVGAIVTETLDEEIVTGTGTLDEEIVTGNLEEETETETSDVEVTVTLDVRTVSAGVKTATWDVVTVDSVVAWMMTGVDPQEQMMEVLGEHQDLLLPEIDVMTVVENGWKDEMINVVVVVVEEATHGVHVRKRAKKNLVKRSHAHLAKKMKMAGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGR2</accession>
    <name>A0A3R7QGR2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TSP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002957</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001399">
        <property type="protein sequence ID" value="ROT78326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGR2"/>
    <dbReference type="STRING" id="6689.A0A3R7QGR2"/>
    <dbReference type="OrthoDB" id="14563at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1080.10:FF:000001">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1080.10:FF:000002">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017897">
        <property type="entry name" value="Thrombospondin_3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008859">
        <property type="entry name" value="Thrombospondin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05735">
        <property type="entry name" value="TSP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51234">
        <property type="entry name" value="TSP3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51236">
        <property type="entry name" value="TSP_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="83"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="TSP C-terminal" evidence="9">
        <location>
            <begin position="196"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="598"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="695"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="731"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="775" mass="83684" checksum="2C1B8CC9D4D38BC7" modified="2019-04-10" version="1">MLPVAFQMPCPTGFAGDGVTCGPDSDLDGFPNIDLPCVDPQCRRDNCPENCPLVYNPGQSDTDADGFGDDCDNCPNDANPTQSDADGDGAGDVCDADADDDGVTNDVDNCIEVANSDQLDLDGDGVGDACDNCPQDANADQVDSNANLFGDACDDGGDVNEDGVGDVCSQDYDGDGHVDATDTCPNSGALWHESLGTLQVVQLYFDYTPEWTFSKDGLQSYETKISDPTMALGNVRVSGVDLEVTIFVDSDYGDDFVGFTFGFRDHSSFYVVMWRQDKESKYSASSAKGIFLKWVDSAQGPGSTLRSDLWSDDSSGETIVLWKDRFPWSRKLSYRLRVLHRPLIGALRLYLSSGKTLLLDSGNIYDSRLAGGRFGPFCFSQNNVMWAQLQYKCNDKIPQKMYDDLPTSSQAVAEVEDDPMYPLCWDCHFYADCNIVGSSHTCTCKPGYTGNGKSCINPCQHTVCPEGSFCNHTFTGSFYTCTKFPAWLVESPCPDGQAGNGTVCGLDSDRDGYPDVALECLDQRCAQDNCVYVYNPDQLDADGDYVGDACDLDIDGDGRNTRFDNCPLVINFDQADYDDDDHGDACDNCYAVKNPSQRDIDGDGLGDECDDDADADGIPNANDNCISVSNPDQLDSDGDGVGNACDNCLQVPNSFQNDTDEDLVGDDCDTNIDTDSDGVQDDLDNCPNVANPDQRNHDGDAAGDACDDDADGDGVLNGVDKCPLVHDPDQLDVDGDGVGDVCENDYDQDGVHDALDNCPENNAIFTTEFVYGIWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKE1</accession>
    <name>A0A3R7QKE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative irregular chiasm C-roughest protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_025172</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000936">
        <property type="protein sequence ID" value="ROT81674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKE1"/>
    <dbReference type="STRING" id="6689.A0A3R7QKE1"/>
    <dbReference type="OrthoDB" id="6413693at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005911">
        <property type="term" value="C:cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051275">
        <property type="entry name" value="Cell_adhesion_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11640:SF31">
        <property type="entry name" value="IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11640">
        <property type="entry name" value="NEPHRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="72"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="228"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="265"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="312"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="416"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="320"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT81674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="515" mass="55922" checksum="5D0640090D45B9CB" modified="2019-04-10" version="1">MQWVDEKGSVITKGTQYHRRVRPDGKLIDTNFTYTFTPTRHHNGRTLTCQVFSPALNTALTTEAVIRVKYPPYVQLVFSPTKLKEGEEAFVTCKVDANPNNVTYRWFREGKEVLGVAGATMPLGVLSRSNQSATIACEVTNALGTARKTDQLNILYPPMFLAEPSSVSGEIGNMVTMKCRVDANPLVGKGEELTIEASKATAGVYVCSARSETFPPLDAQLHLRLRGPPRIKTPAVLVVREGQNAVLRCSVVSVPHPVSLAWEKGGERKEKAADAPEKGAFANGISGKHHESQDVNGGGGIELAKTEKVLPNLIPADARSTGKDSDNKEERSRANSSLSDGERESDSGWEKNSTNCSGKRVLTPSLGRAHYTSATTVFPPPDDDYMPYVDYTRDYLRVPVSPTDSSTHFQIGGPYSCYTPASDQPSSLPSSESLPPYTLQPQPTADFNGDYANGRHHPPANNDAVTVNGRLKHALLQDLKKELKGGGMPHDLNTGALQSKYIIPPQTKIKPGTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNS2</accession>
    <name>A0A3R7QNS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative OTU domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000449">
        <property type="protein sequence ID" value="ROT85069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNS2"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="151" mass="16875" checksum="E4BADDC7B7C46E63" modified="2019-04-10" version="1">MIVAIRTPLTHIHTGEATRYLSSSSPPPCWPPPPPSATPREEKRPSHASPTHFEDSHESGPSHSKRRYRASPLRSVRPKHRDHREHRGNASPPYPSTSSGWSVTQLYLQHFLLRLGHPSLVRKRRMTTAVTIVAMSTSHLGGTSQQTSGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNZ3</accession>
    <name>A0A3R7QNZ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ectonucleotide pyrophosphatase/phosphodiesterase family member 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000328">
        <property type="protein sequence ID" value="ROT85301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNZ3"/>
    <dbReference type="STRING" id="6689.A0A3R7QNZ3"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="309" mass="34612" checksum="FA37DE51095F82CC" modified="2019-04-10" version="1">MWPGCDKTYRGRNVTYWTPYREDATFRESIDKAVEWMTDATTPANLVFLYVQEPDTVGHAYGPNSSYVVEELKKIDENIGYLYKMLTIFNLLDTTDVIVLSDHGMVAVLEENIIDLDQIVDPKLYHTSGGSPVMHIWPYGDLLDLYIKFDNGAKTHKYTVYQKKNFPSGWHYTNNSRISRLVLVADRGFKAPSFSNVDVYPLLCHLLSLPPGPNNGTLKDIGTVLSHPAVAELAKPLLIALGCLVILVGLIGILACVLSRRDRRAVSADSLINGYVHRRVMRSESSKLADDDASEEECLLESEVVTVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QR82</accession>
    <name>A0A3R7QR82_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Oplophorus-luciferin 2-monooxygenase non-catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_006262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001802">
        <property type="protein sequence ID" value="ROT75203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QR82"/>
    <dbReference type="STRING" id="6689.A0A3R7QR82"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24366">
        <property type="entry name" value="IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018712042" description="Oplophorus-luciferin 2-monooxygenase non-catalytic subunit" evidence="4">
        <location>
            <begin position="20"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="342"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="385"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="47415" checksum="E80D5573BC0818F9" modified="2019-04-10" version="1">MTMQVEVIILALSFALCGTFPWHQTPSGQEARPRADPCPSADLIAPCECWEEEELPGVFLQDFPNPNLMSLTVARSNLGHLPQDIFHGKTFQSVRLTGGGVSSLAPAALDNSRETLTQFFVNDNQLTNFSLQDLHLFPHVNALYLSNNQLLSIDALVGMPEQATLSAFFVSQNYLTSLHPDVFKSVPGIGSLRLDNNRLTHLSPRLFYPLYQLQVLTLYDNTLLQLGTGDLWFSTPILRSLDLRNNGPGLLWEADVFRGVGFDTKVDLANNRFHKLEYDVFGPVLKNVSTFFGFVSNYLTCDCSVLWLVMDEALQRHAYSATCKNFTYVDDLDRDAMVRNAHGPDALKQPSRLPPSKHLPDFPLRSPRLDPQQSFYLNKDSPNPYLQPPLPPSPPHPNPYLRLPFPPSPTFNPLAPPPTSPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QY01</accession>
    <name>A0A3R7QY01_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000796">
        <property type="protein sequence ID" value="ROT82621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QY01"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="387" mass="43405" checksum="9C107011C119CBEF" modified="2019-04-10" version="1">MSFASSLAVSGLKTLFRTFRKGLEYHDRPNPYCISKNIHSRFFIFFSLLTLFPAPSPPPLFPSCSLLSIFYYASSSLSLRFLSFPLFLSSFLSFLSFSPYPLLPPHSPVSLLPPSPLPFSSPPPPLSPPTHLPPTATPLLNPLPHPTSPSPLTYPTFLPPSHPASLPPLLHPNPTPPPPHPYPPHLHLSLPPTPFLPPTHLLTLIPPSFPFPPNLPHTPTLLPLPPTPHPHPPHPPSTSPHPSHLHLPHPPPPLCFSSRGMAEPREDDPQSLSTGLCVGLIDTPAPPPRSAWISIRVDSVALGEVDVEVDGVWMWMGCGGMWEDVVDWMWRDVDWVEWIWMAWWMGVDGVDLVEVDWMWMGWIWSKWMWMGWICSRWMDVDGVWMAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SKD3</accession>
    <name>A0A3R7SKD3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative DNA-directed RNA polymerase II subunit RPB1-like isoform 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003222">
        <property type="protein sequence ID" value="ROT64616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SKD3"/>
    <dbReference type="STRING" id="6689.A0A3R7SKD3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="entry name" value="Serralysin-like metalloprotease, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="Adhesin YadA, collagen-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="642" mass="72338" checksum="DED33261A03FF11E" modified="2019-04-10" version="1">MLTWVRGGYTACWHGCSSDGVLIFVHLIWICSGSRISQQEVCRRIMLPRQVDIGQVLKSSLPLEVLSPERPAFSPERPAFSHERLAFSPERPASSPERPAFSPERPAFSPERLAFSPERPAFSPERLAFSPERLAFNPERLAFNPEQLAFSPERPAFSPERPAFSPERPAFSPERPAFSPERPAFSPERLAFSPERLAFNPERLAFNPEQLAFSPERLALNPERLAFNPEQLALSPERPAFSPERPVFSPERPAFSPERPAFSPERPAFSPERPAFSPERPAFSPERPAFSPERPAFSPERLALNPERLAFNPEQLDFSPERPALSPERPAFSPERPVFSPERPAFIPERPAFSPERPAFSPERPAFSRERPAFSPRQPTFSPERRTFSPERLAFSPQRPAFSPERPAFSPERPAFSPERPAFSPERPAFSPERPTFSPQRPTLSPQRPTFSPERPTFSPERPTFSPERPTFSPERPTFSPERPTFSPERPAFSSERRLSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRLSVLNGRLSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRHSVLNGRPSVLNGWLSLLNGQLSLLNGLRTQFSIRSLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SPE2</accession>
    <name>A0A3R7SPE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative MAM and LDL-receptor class A domain-containing protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012412</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002567">
        <property type="protein sequence ID" value="ROT69404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SPE2"/>
    <dbReference type="OrthoDB" id="409956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051560">
        <property type="entry name" value="MAM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282">
        <property type="entry name" value="APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282:SF146">
        <property type="entry name" value="RT07201P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018778931" evidence="1">
        <location>
            <begin position="29"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="30"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="218"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="397"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="572"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="745" mass="81922" checksum="4D7A215742A27770" modified="2019-04-10" version="1">MSDSNTKSRMKMVFVFLAFALGATPVHAQADCSFNATGSLASVCSLLEDSDAFAVASWRVGTGTEPTGWGPPVDNGNDPRGYGFTTAHDMLHTAQPHKKAWLVTQPSARTGPQGKCLEFAYATYGLGIEEFQVILLTYLTEDVNDALQNASIPVTFKRTNLMKHKGSTLGQWEQARVTFSAKGDFSVAFEAVPNAMYGRYTGYVAVDDITFKDGPCENECIFDLNFCELTNEPNNDDFDWSLGRGSGKTNTGPTRDQAFYFTDSVTSGGYAFIDSRYPRTAGEVAQLVSPALDATDSPMCLKFWVNMYGTGIGALRVLYVPTTTPDNIRELWKQEGSSSGPDYWYPSQVTVFSAENFNLVFEASVGSQGSGDIAIDTMTYSPGPCPRQPSLSSSSWGDCTFMENTCGWQIPYFPDEVCSMLGRVSENSENPPGHTENDFNLRDSYIQFDLNCYQQQPRHAVSLTFENANIASEMCLSFWVFMYARVQSVSKIGALSVVLRTAGGNETLWRLENEQHATWMYAQVTIPAVGVASVAFQGTKAASLIGMIGVDDVAVFNAACEVLPEQARVEAADCSFDQDLCGWSAQNESPSARPSEVWRLATREGSVGSLLDHTFGADGGGYVYLDVFNTDVVGWLRSPNNLEKNATYCLSFYFAALFPDARDELAVVKDLVGTQERVWRVGGDSVRFEDNQWYKGQVELEAVEDGFTLHFEGRVSRGGWALDDVRLRKTRTSCKMTPDFAEQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STR9</accession>
    <name>A0A3R7STR9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative transcription factor E4F1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_006801</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001861">
        <property type="protein sequence ID" value="ROT74687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STR9"/>
    <dbReference type="OrthoDB" id="4748970at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000710">
        <property type="entry name" value="Zinc finger protein 768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041697">
        <property type="entry name" value="Znf-C2H2_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF13">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF49.1-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16622">
        <property type="entry name" value="zf-C2H2_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13894">
        <property type="entry name" value="zf-C2H2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="236"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="443"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="471"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="499"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="527"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="555"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="604"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="606"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT74687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="724" mass="81870" checksum="AD7DFF1CBF2EBC0E" modified="2019-04-10" version="1">MKLSDIESYVTHMVLKEQCVLHLCPSITVRDLLLPRFSRKKLREEVEEVDIKQVKQLIPGMEKEGLHEMKNDDVEVIVQATEIETGGKKRWKCHICGLTFSRQAAIANHHKLQHRGSAEKKQGTEITEDEYREMHVKKEAAPDSKIPVKHIVAVQSEVQVKHLADELAYREKEWTKPTCELCGQTFKTGKILRAHNAIVHSHGRPFHCDFDGCSQSFKTKGSLTRHLRRHTGERPFSCHDCGRCFRESGSLARHQQSRVSCVDKKDSQLPLYGKTKPIDSSHLERKPTVHQMKLNSILKQENFSGSGDSDDEDISKKISEESKVSVRAGVMASKSSGAPVIKQEENSLNHLRQNSSIDVGRTLVSCKIEHNTLSSLMEEEELDNDLIMEHADDMETKLSDIKPPQLSLDIMRKSFTCPVCCRSYARKSTLMLHMKNHLDQLGEQCNQCGKNFANQQSLSRHLVSHSSVRQYVCQLCNKAFKLLSHAKGHLHSHSTSKTVPCRYCNSFFKTVSARNTHERTHSNARTFVCLECQKSFVTKASLIRHLRIHTGEAPFQCQYCGRCFKEHGTLSRHLKHKMPCAQQSRLEKESGDLGIRLFPGNTPRNFEVEANRNNEDQKSEVAPNESLEDTASLKSSIFEDEDEEANTHFLLLKNNYVASSRRGSIEEADLEPLSTDILQPSDAVDSHGPGVVVEEVRGDETSYIIISGDNSPLMTLAVDSKDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-05-03" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SU92</accession>
    <name>A0A3R7SU92_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001784">
        <property type="protein sequence ID" value="ROT75333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SU92"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="539" mass="55510" checksum="6C722E488D3B88EA" modified="2019-04-10" version="1">MVVSGVLGPPGAQDGGLVVSGGEWRARASRGLRIGGECVLGPPGGSGLVVSGGEWRARASRGLRIGGEWRARASRGLRIGGPPGGSGLVVSGVLGPPGAQDWWMVVSGVLGLPGAQDWWIVVSGGEWRARASGGSGLVVSGGEWRARASRGLRIGGGEWRARASRGLRSEWWGAQVVVSGRARASRGLRIGDEWRARASRGSGLVVSGGEWRARPPGGSGLVVSRASRGLRIGGEWPRASRGLRIGVSGVLGLPGARLVVSGVLGSPGGSGLVVVSGARASRGLRMDGGEWRARASRGLRSGEWRARAPGGSGLVVSGVLGLPGAQDWCEWRARASRGLRMVGLPGAQDLVVSGVLGVSRGLRIGGEWRARASRGLRIGVSGVLGPPGAQDWCEGGAQDGGEWRARASRGLRIGGEWRALRGLRIGGGGLVVSGVASRGLRMVVSGVLGLRGLVGGEWRARASRGLRIGVSGVLGLPGAQDWWASRGLRIGGEWRARVSRGLRMVVSGGEWRARASRGLRIGGEWRARVSRGLRIGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T1B7</accession>
    <name>A0A3R7T1B7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015745</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000297">
        <property type="protein sequence ID" value="ROT85370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T1B7"/>
    <dbReference type="STRING" id="6689.A0A3R7T1B7"/>
    <dbReference type="OrthoDB" id="73875at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000001">
        <property type="entry name" value="Chitinase 3-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="7">
        <location>
            <begin position="47"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="404"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="433"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="57248" checksum="6C3FBEA8D0C37820" modified="2019-04-10" version="1">MQAGFQEGKGTAEEICNRLLDEKYTEHEQYIYHNFIDFKKRSRIDAHTRKCLSPSSTGAARHTVDDVPVELCTHAIYAFAVLDADSLVAREHDAYLDKAAGLDNYRRFVTLRERNPQAKMLLGLGGWTDSRSDKYSRLVSEPQRRAAFVSHVVSFLQEYGFDGLDLDWEYPGYQSSPQDREGFRLWVEELRAAFSPHGLLLTAAVSAGRDVIDRGYDVPAVAEALDQIHLMSYDFHGSWEGRVAHHAPLFPAPGQEKELSADFAVRHWIKRGAPASKLVLGVPFYGRSWTLAGADASSGAPASGAGRPGPLLKDAGTMAYYEICQAHQRGGWRKVSGPDGPHLTHGDQWVGYDDIAAIRKKALYAQQKGLGGVMVWDIATDDFRGTCGRGANPLLSVIAKVLTGSSPGSSARPPTARPSTPRPVQPTTLRPVRPSPSRPTPTTPSPGGQVERQDSWPGKQTAHLRGLPEKSLIFDATHHHKKTSGPQARLSIAAVARSAGRRPGVFRQDWAIAEGMAAGRSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S8S3</accession>
    <name>A0A423S8S3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004672">
        <property type="protein sequence ID" value="ROT60629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S8S3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019164085" evidence="2">
        <location>
            <begin position="20"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="682" mass="73418" checksum="3E05F44A2D74BBAD" modified="2019-05-08" version="1">MATQTTVAVLLVCLAAAWARDRLNSKRLRWEGHDAEARGEGPLAPRAVLVPVVSRADRKIIFINNKAYDMPEEEQDLLWYLFLHEGFVPETAHFVPEPQMDSLAAALHSPGGTAVETDGRLQVMDSAHNGLDGEGAAHESVKTSRLVSGPEEEPRDEAEAQPDAPADDLADDRLADAGTEPVSAPPADPPGAPLASPSNRTANASEPAKTKDRAEIEVAGDDKTAEVAPARRVSVLAFLWAQLTNIGGMLGRSVVDTLSDTLWAGWLNMLQMVKSRGIGRTLPEALWNSWLSVLQYVNSRELGDPLPEALWKSWLTLLQFVKSRGRRAALDLPPEAKRTGGPACLRGSCFHDGTLFLTEQVLPPPLQQVLSSAPPAGPSSAPPIHTNVLTFLATPQEFLLLPRGRAPCLRNRCFLPPSNLHKPTTSIATRLTVRDGQPFGRGGNRGLPAGHGSLGALVAGEGQAWDDAHGEREASPRVKCYVFSAKFPRPVLEYSWPTAARTPVFTVYLIASFVTVNREPSSVVLLATLAPPISAQPGGQKDNRAADSADPYSCNSSHVSEEAIRGYCPKYARSPIPSLHRNGREPVNQLRLAGVTSQLAKAAAGDARSSPRFISRGSSLLSVLHSLGSSLLAGSSLLGSSLLSDFSRFLTLAFLILIPQRFNVRRLACLDFAKTLLLRPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S914</accession>
    <name>A0A423S914_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004609">
        <property type="protein sequence ID" value="ROT60712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S914"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="520"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="877"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="983" mass="106692" checksum="F601FF1E348F55E9" modified="2019-05-08" version="1">MSPQQKSLFSRTSVSSAEHQSLSMNIRPLSKHPVPSAEHPSPQQKSVSSAEHQSPSAEHPSPQQNIRPLSRTSVPSAEHQSLSPSRNIRPSAEHVSPQRTSVPSAEHRTSPSAEHPSPQQNIRLLSRTSVPSAGTSSPSLSRTSVPQQNIRPLSRTSVSSAEHPSPSAFSPQQKHPSPAEHRPLRRTFVSSAEHPSPQQNIRLLSRTSVALSRTSVPQQIIRLLSRTSVPSAEHQSPQQNIRPLTRTSVPSAEHQSPQQNIRPLSRTSVSSAEHPSLSRTSVSSAEHQSPQQNIVPSENIVSSADIRPLSRTSVSSAEHQISFPSAVPHRTSVPSAEHPLSRTSVSQQNIAEHQSPQQNIPSLSRTSVLQQNIRPSAEHQSAEHPSLSRHPSPQQNNPSPQQNIVPQQKHPSPQQNIRLLSRTSVPSENIVPQQNISPLSRTSVPSAEHPSPQQNTVPSAEHQSPQQNSHNISPLSRNQSPQQNISCPQQNIRPSAEHQSPQQNISPLSRIFSPLCTTSVPSAENQSLSRTSVPQQNIRPLSRTSVPQQNIRPLSRTSVPQQNIRPSAEHHSLSRQSPQQNISPLSRTSVPSAEFQSSLPSAENQSPQQNSSLSTSVPSAEHPSPQQNIRPLSRTSPQQNIRPLSRTSVPSAEHHSLSRISVPSAEHQSLSRKSVPLSSIRPSAEHQSPQQNISPLSRTSAEHQSAEHQSPQQNISPSAISPSAEFQSSLHNISPQQKSVPLSRTSPQQNISLLSRTSVPSAEHPSPQQNISPLRTSEHQSPHRTSVPSARISVTTSVPSAEHQSPQQNISLLSRTSVPSAEHQSPQQNISPLSRTSVPSVEHQSPQQNISPLSRTSVPSQNMSPQQKSVPSAEHQCPQQNIRPLNRTSVPSAEHPSPQQNISPLSRTSVPSAELQSPQQNISPLSRTSVPSAEHQCPQQMPFMPEAHLASVPRLCPVPPVPVSSACGTWDAEEAGGSNLNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBU4</accession>
    <name>A0A423SBU4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Caspase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020513</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase C14A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBU4"/>
    <dbReference type="SMR" id="A0A423SBU4"/>
    <dbReference type="STRING" id="6689.A0A423SBU4"/>
    <dbReference type="OrthoDB" id="6114029at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002398">
        <property type="entry name" value="Pept_C14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002138">
        <property type="entry name" value="Pept_C14_p10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001309">
        <property type="entry name" value="Pept_C14_p20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015917">
        <property type="entry name" value="Pept_C14A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901">
        <property type="entry name" value="CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47901:SF8">
        <property type="entry name" value="CASPASE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00376">
        <property type="entry name" value="IL1BCENZYME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00115">
        <property type="entry name" value="CASc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50207">
        <property type="entry name" value="CASPASE_P10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50208">
        <property type="entry name" value="CASPASE_P20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Caspase family p20" evidence="7">
        <location>
            <begin position="279"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Caspase family p10" evidence="6">
        <location>
            <begin position="451"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="516" mass="59987" checksum="8FC654857B3DB6FD" modified="2019-05-08" version="1">MLFLSINPNKIEEQDTPSGASGYTDSISIYKNVVVPKFRPNETSDSVTKLLEKFKSSLSEKSIAPVRRELEHRILKLKSVQLNTNTLSTLESNLLKKYDQLSNEEEDILEFTEIFEMFNLSLPESIRVNFGNIISSKKIPLKRGDIGNHSKTFFVYAENKIMMKICDSLSPQDVYRLYEIIRELEDIEKDDKVKDLLSQQIDQGALEEVPGLKDVAFYYLTLTMMRKQLLNRLYTHRLAFLFDQLKEMKSGKDPNIDRILDTLNRYPVVSRPPGLCIVFNITENREGSTKDVVKVKELFEKEYKFDVLVKEDPTANEITDIVSELKAARYKFYDSLVVWFMSHGDETFLQVKNEKLIHRRVELIQPFTEIEWFNKKPKLFFIQACAGKENRKRSWSQSQSEDCAKSGWIAPAGSEWLSKYGCNIDVSRVNSFADTLISYATMWYQPASRGKEGSLYVDTLVDQLREHGWKENIENVLRRVHYNVNTVTLNSEQRIKWKQAPYFESSLQKAFIFPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCL4</accession>
    <name>A0A423SCL4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_020193</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003894">
        <property type="protein sequence ID" value="ROT61982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCL4"/>
    <dbReference type="OrthoDB" id="6336709at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT61982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="128" mass="14239" checksum="741B880D0C7AA09E" modified="2019-05-08" version="1">MNGPRERGEHRPGAAPRVRGGSGRAGLGGALAGAWEPPILGIYTCHMCGFKSGNKIELNNHVRVHTGGWPYVCALCDYKTRRSNDLKRHELTRHQGGVLRPFRCDLCQYRTTHAVLLRRHRAAKHPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDH7</accession>
    <name>A0A423SDH7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019911</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003746">
        <property type="protein sequence ID" value="ROT62253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDH7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="562"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="621" mass="70630" checksum="290E2647040F8A90" modified="2019-05-08" version="1">MPTHTTPFSPPYTPIPTHARKHTDKHRRTAKPRDTDTRTAKPRNRHTRTANPCNRHTRTANPCNRHTHSNPCKQTHRTANPCCNRHATAHTTCNRHTRCNMQTACNRHTCHAQPCNRHMHAQHTRTDPHATAQPTHARHTAQPTPCNRHTRICNSNRHTLQQQPQQTHTHSQPMQQTHTHSQPMQQTHTHSQPMQQTHTHSQPKQATSAHTHAQPTHNRHTRTANPCNRHTTKPCHATDTTANPCNRHTRTANQPTDTHAHSQPMQQTHTHSQPTDTRKPTHAHTRTANPCNRHTRTAKPMQQTHTHSQPTQQTHTHSQPMQQTHTHSQPMQQTHTHSQPMQQTHTHSQPMQQTHTHSQTHATDTAQHSQPMQQTHTQPAMQQTHTHSQPMQQTHTRTANPCKQTHTHSQPTQQTTHAQPTHATDTHAQPTHAQNAHATANPCNRHTRTAQPDAHAQPPMQQTHTHSMQTATDTHAQPQQTHTHSATDTHAQPATDHAQPNATDTHAQRNRRTPHAQHSQPTHRRTPQPTHATDTHARQQFAMHCNRHTRTANPRNRRTRTATHATDTHAQPATDTHAQPTTQQTHTHSQPIATDFQNLNIGLIKFCRPVWLPDHSGELVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SE63</accession>
    <name>A0A423SE63_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003664">
        <property type="protein sequence ID" value="ROT62488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SE63"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="538" mass="60490" checksum="D9609320D70226F3" modified="2019-05-08" version="1">MVLTKPERILDVERIFRETTTLLSQHRTSRMKKKNDDNAIDSAAPALRSIFDSLYKNLALISPDNNNNNRNSKRSLVSDVRQLALNLNEKILSKNIESIEEAINAKLLKELVSDVKLAYNVTNAIDSSSNLKSLGNVLRKGFIDASVSEDMEIFKRSSILSRYMLLDERCQLFPISAETKELLLEGSSQAATARAILSESNQLLTDAVMYNTRDTPVEKAVDRVLLLPYLVKQGRDFDDVDRTLPVAITNCSSLMLSLLDSQSMSRSPFLGGLMGHVTDTTSVFKNIERFERLSGRLGDVASMLHHQNCNCPFKFHHCSDRTEEENLMPSFIHFEDEIDKCEISKTPYQVHVLMAIKNYVANISRIDPSVGGPSVIRRLREWSDMGAGTRYIGSFIADRKTVQDSPFRVAGSNLDVIVRPAAAREQRLANVEAPHLSDMNVDNAADNGRPSACENRSFGSQIRNEISRMIWYRNHRRRTRLIQRPETLRLTAVGYPFSTIPNTTAEPPPPPPLLIAVAIGYGDRPHGKIWPRSTFGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGC6</accession>
    <name>A0A423SGC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Syntaxin-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_018895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003471">
        <property type="protein sequence ID" value="ROT63241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGC6"/>
    <dbReference type="STRING" id="6689.A0A423SGC6"/>
    <dbReference type="OrthoDB" id="546861at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15851">
        <property type="entry name" value="SNARE_Syntaxin6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000006">
        <property type="entry name" value="Syntaxin 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015260">
        <property type="entry name" value="Syntaxin-6/10/61_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09177">
        <property type="entry name" value="STX6_10_61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="183"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT63241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="30854" checksum="A208FBB9E02707D4" modified="2019-05-08" version="1">MSQPQICEQDASYPTPPSLSLPPVLPKIPRGSGGRRPPPPPPHVPQLVRDLLHEVEVELSLYVAAAALLYAFLLVFLNTESSRIVEKNPRKFKIDGGELTARRTFIEHTKDEVKSMKDRLNLTKKDRDVTARQVSESSSPIDDNSPLKMPQVVTHGSTRYSRLVNEADSPNSEFIERTLAQQQMIMHQQDDQLDQIASSMGTLKNMSRQIGQEVDEQAVMLDDFGHEMENTQSKMENTLSKMAKVMHLSNDRRQWAAIGALSGVLVVVVILFFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGZ4</accession>
    <name>A0A423SGZ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_018586</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003429">
        <property type="protein sequence ID" value="ROT63517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGZ4"/>
    <dbReference type="STRING" id="6689.A0A423SGZ4"/>
    <dbReference type="OrthoDB" id="10004641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000075">
        <property type="entry name" value="Putative zinc finger protein 536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408:SF58">
        <property type="entry name" value="TRANSCRIPTION FACTOR (TFIIIA), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05150)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24408">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="106"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT63517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="315" mass="34702" checksum="FB35AA02ACC0EDCC" modified="2019-05-08" version="1">MFLPYVTAVFVHFHETDWPVHRCHGFALSRAGARRARNKPKPETSGAWTALFAGAGSAAWRTCGATCARTRARSRTCAPCAPSAPPSRAASTATCAPCTTWTRARRTARRSRSSRTCPRDRSARRRGRREDLAARRPPREERPQPRDRRQDSILGGAKSSVVAAFCEPSCAGYDLLLGYEHEHLWAVGARAPEGRSGKREGQDQQERGAAWVGEDACARRHVCGVCGRGFRLANDLRRHLRIHTGEKPFCCPHCPYRASQKQSVNRHVRTVHADLMLLERGPPARPPAARTVGQRCQGHGLCLSLVSSACPASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHH6</accession>
    <name>A0A423SHH6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018433</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003399">
        <property type="protein sequence ID" value="ROT63676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHH6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="686"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="852"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="928"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="442"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="786"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="928"/>
            <end position="943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="954" mass="101145" checksum="D791499EACBEA5F0" modified="2019-05-08" version="1">MLGINSRHVRIQGYYSERRPPPPIQVFRPPSSLHIPQVFLGQSFVSQVFLGPSSPPPFSAQSSSLHLQGLPRSVFVSHLHPLGLPRPSPSSLRSSSLSSFVSPPPSPRSSRHSPSSLHLHPPRSSSAQSFVFHLHPLGPGPVFLGPVLRLAPHPQVFLGPVLRLSTSIPLGLPRPSPSSRHLHPPRSSSPQSFVSPPPSPFVSPPPSPRSSSPSPSSRHLHPPRSSRPVLRLSTSIPLGLPRQSFVFLGQPFVLSIGSSRLNPSSLHLHPPRSSSAQSFRLSTSIPLGLPRPSLRLSTSIPLVFLGRSFSFVSPPPSLGLPRPSPSSLHLHPPRSSSAQSFRLSTSIPLLPRPVFLGPVLSSRHLHPPRSSRPSPSSLASIPHLHPLVFLGPVLRLSTSIPLGLPRPRSFVSTSIPLGLPRPVLRLSPPSPVFQSLHLHPRSSSANPSSSTSILGLPRPSPSSLHLHPPRSSSPSPSSLTSIPQVFLGSVLRLSHLHPLGLPRLSPSSLHLHPPRSSSPSPSSLHLHPPWSSSAQPFVSPPPSPRSSSAQSFVSPPPSPPRSSSAQSFVFLALVLGPVRLSHPPRSPRPVRLSTPSPRSSSPSPSSLHLHPLGLPRPSLRLHLHPPRSSSPSPSSLHLHPLHPSSLHLHPLGLPRPVFLGPVLRLSTSIPLGLPAQSSLTSIPLGSSASPSSLHLHPPRSSSAQSLRLSNLHPPRSSSAQSFVFLGPALRLSIPLVFLGPVLRLSIPPGPSPSSLHLHPQVFLGSVLRLSTSIPLGLPRPSPSFSHLHPLGLPRPSPSSLHLHPPRSSSAQSVSPPPSPSFLGSVLRLPPPSPRSSSAQPFVFLVHPSSLHLHPRSSGSILRSPALPRPSPSSLHSIPRSSSASPSSLHLHPLGLPRPSPSSLHLHPLGLVGLLSPCLSTSIPLGLPSPSPSSLHLHPPRSSSAQSFVSPPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJV3</accession>
    <name>A0A423SJV3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017622</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJV3"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="730"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="805"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="826"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="927"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="945"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1007"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1127" mass="126081" checksum="41543A8F51A9835B" modified="2019-05-08" version="1" fragment="single">NLIATTPEPPAGLTSAPSFLPTVAGPRSTTTAPTTTTATPPTLTPKRRPGKKVVLPSSRKKDDKENETSKPTKTKVAKPERKPDLEQYEKNDVNGIAEGARKPKVYDQNQPAKPHGKPRVKKPFNKPRSPKLFRMNNSVVDQGPEGGRLPVNRKLLKGNQTLSSQHNRQGGSPRPKKKPEQARPNLKAESGLDQGPATVRGERPRHSPWQSKPRKALPHPRPTTTPPHVPRHSALRSDPVSESSEKADAGNETLAHGGDFKSQGLAGTKDATRNEAAVHPHACRDRPGGYICGSISPSSSKGGRTNPYMKRNPNNAVFRRKNNTTSRKNANGTKLHGGRVNMKKHRRQKNRGRLHNRDNKAGRNVTGRGFPSTHKQKKKFKKGKWRGRDWRHRSRHPSKGGQGGQRGNQEPSQGREAQQEEDLEREAVRGHRRWNRNKGRQAGRVHPKKHKGRRPGQNRTNNSTTQSNRTHNHQSTQVPPIPTPTGPTIPKIDSLTIDTPTTDLLSTDLPIVESSVSQTTVPDAPDSVSPRPHVTTNSTAKPRLITTTPRNNRTAPTRRKSKHSRKKGQRRSSHQVPNRQQPSTTARPFAQNATVPPPNNSNVAGEGTALAPQEEHPHRHNHHGKRGRRRKIGKDGTQHGDKKKGSGHRFGKLDRNATHSGQQRHRGGMRKVGKNKHKYRADKRHGNDDSVARPGEGRLRVTHHRKQDGEESLDQDGLDFDDAEDSDEQDSPHSKNKESSRKEKEDETLTEGQDHSEPEEDDRPSEVDGSRSRLHSNAKKHAKGRHGPRRNKPNTLKLNDTSKPTLRRKGKHFLKRTGKTGNPRYGKSRRNKKPPGFHKKNATIATARPSAIVTGSPGLHEQSKASGSNDITENHVLSTVKAGHHHHLPERKSHQRGGRHEEEPESNAILPFDVDKDGGRKQEMQLDATSTVSSLNLEEFPTQTEVEKDHGDRSEDRTNIDNVGRGERKNTGEIFKKEEDEGEAENEEGVAESSEDEGKEAKVDAGTSEDEEADTEEANEDEHKTDAEISKDEEDTAQERAPRRSPEKYAEWGIGPLRPPHRSSRRSRPGWRFQKTFYRRGHVYEDIRRKEKLGSDFIARPSIQPPKRLEEEDDPISFECRIRRKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLI2</accession>
    <name>A0A423SLI2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017016</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003152">
        <property type="protein sequence ID" value="ROT65033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLI2"/>
    <dbReference type="STRING" id="6689.A0A423SLI2"/>
    <dbReference type="OrthoDB" id="18798at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051065">
        <property type="entry name" value="Ras-related_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45704">
        <property type="entry name" value="RAS-LIKE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="685" mass="75427" checksum="3C97F443355AF122" modified="2019-05-08" version="1">MYQHSTTVDQTLTQLQLLDAAPAQSSHTLAQHRRWADAFVVVYDVTNRTSFSHARGLLHALHAPSDTRPHSRSHQPNYVEKYFKRDTYADDASSQTPSHDTGSISRRCSSPSQSFSPSQCSSLSLCSRPHQCSSSSQCSRLSQCSSRSQSSTPSRCSSPHRCSSSCRCSSPLTCSIAPRCSSPSHSDHPGRESPTANLPSSPPCIKQLFIPPFSRGLERDSFAPEPQDNKQYVDQSQSSTCDEDPTDGGSTSQVQFQYQYCHSYKTDPQTCVNVECICDQNDNYKQNCDTTAISCESAHIREKQVHDLNKTQRMETPPCTGAPFTVKALLTDRDVYNPDHPDPCTPSACIRDREQCCPCDSGAPAHLQTQSSLQLLDETRLRSYTPDFVQGVNPDLENSPDDIDHCLSQDQIRCGGNTPPQHCLSSHAPLADSPHCYETGRNACQNTGSLRPPPQISGDSCVSSNCLDSCQLVTSGSEHNSISPALAHDYRIAPEPDDHLYQTVQRLEASAGTPPRTPAFTTLLLANKRDLEHCRVRRTQKWRLGSKSQMVTEALIRGWQMVHEATYRTHDGRAWARRYLLSVGFMIPLPVGVCVQADEGEALSLEFGCQFHEVSAAESLAGVHLAFQSLLKETLARMIIKGLPKGRLSSPVEDTTTVSAVSRVIGNILSRAGRGIRKKRPSHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPB4</accession>
    <name>A0A423SPB4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003001">
        <property type="protein sequence ID" value="ROT66021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPB4"/>
    <dbReference type="OrthoDB" id="6348363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018966437" evidence="2">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="182" mass="20241" checksum="05EDF6CCE9DD188E" modified="2019-05-08" version="1">MASTATSVLALWLLCAPRAEAALEEIEATPTNTNGIEIGELSFMQLLLLMLVFLKLVTLYSLGVLPIEIDLGASFTGFTSERGLVDKDAEMSTYLLDCPLQFVCDVDAWANRDHDYYLESLVASWFRNSNHTWQRPDSEVYGGRGTCKEMYPCPFDVQEVVGIRIPGSNALSGTEEESYSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQS2</accession>
    <name>A0A423SQS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_015371</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQS2"/>
    <dbReference type="OrthoDB" id="6332316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15079">
        <property type="entry name" value="7tmA_photoreceptors_insect"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000044">
        <property type="entry name" value="Opsin, ultraviolet-sensitive"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001760">
        <property type="entry name" value="Opsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00238">
        <property type="entry name" value="OPSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0157">Chromophore</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2 15" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="4 15" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="17">
        <location>
            <begin position="68"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="353"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT66572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="42445" checksum="4C188F32ECDCCE63" modified="2019-05-08" version="1">MSTWNSPVQDTVLPSTNPYGNYTVVDTVPESILHMVHSHWYQYPPMNPLWYGLLGFWMVIMGTLSLAGNLIVIWVFMNTKSLRSPANLLVVNLAISDFFMMLTMTPPLLVNAYWGTWILGAFFCELYGFFGSFFGCVSIWSMVFITADRYNVIVKGVSAEPLTSGGAMLRIAGTWLFTLAWCLPPFFGWNRYVPEGNMLACGTDYLTETELSRSYLYIYSVWVYLFPLAYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFVAWTPYFIINWGGMFNRTMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACRTEGRDDGGSDAGSTATAQTSEKAEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXH9</accession>
    <name>A0A423SXH9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002624">
        <property type="protein sequence ID" value="ROT68899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXH9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="449" mass="51286" checksum="5D346B4A2855D351" modified="2019-05-08" version="1">MPGRGRSLRVTRSSSQPSSRTSSPDNRTALPVIVVQGSNTEVQDAVRAVEGEVTMMEEMLQRMTNLVAQNREELLRRMEEIARTSEDRLQRLEDQLQERTAPAEAVVSRSNGSQLLGKTSRNGSDNWRKGKDAYTTRTGPLHSQPKPPAYRRMEAAQGDLLAHPRSPSHFREARQTFPEPAPRLSTPVHRDEPAEDHLRHQQPSLISRDVIPYLVSRDSIPHFKGETSACEPLKRNQEVESYIRAIENLVRPATDDAYIRAARASCRGRAETIINSESFDGIQDWDTFKRQLRRKFRGTYSASDFFKVLYDHGMTERQAPMDFFLEVEASVFQGYRDHRGAVGEPSELIRRVFLAGLPSTLRDLLVLKDDCSPIQLAETAQKLWNSRYGIRHSSSNTRHQSPNNIQEDDYQLRRRTPDRPPRTRDRYDLFLLPPHRTCSVSFLASNITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SYB9</accession>
    <name>A0A423SYB9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Versican core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="418245at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="849"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="726"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="892"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="941"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1348"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1455"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1469"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1479"/>
            <end position="1500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1613" mass="174393" checksum="AD66D47CE2BCA035" modified="2019-05-08" version="1">MAIPAVPPRGCWLFLFPSFMSVILHPSSPSSSIPLVVFPLVAFSFYSLSFLSRSFRSLSMPFLLFPFSLTHHLLSLDPQAMFFFSFTAPPHPMQSSTLSILHHPPFLNTSPYFHSPALPSPRPPPSCLPPSSHLPPPSSSLLHRLSFGTTSSHPASFCPLPPPAPPVLPLQPTPFPLLPSPLHSVSASSTHLPPSHPYTPHCPLASSTTARPPLKPHTLSRAVASAQHTRGPSRASSTALMENQFQNSYPRILLEVSAGENLTTAWRVSLALSSLRIQNLGFPHQVCHCSHLHTTSPIHHPSPPHFTAFVPAVHASQPIQSPPRRRPSHPSTPPHISPTNGFLSPPLSLHLHPSELTSNPPSHPVLSPRSHRHPLHATPSSVTHYSPHLTAPRHPLLPSLRSSAASTSSSPRRSSHKCRSQTVSPRVDSKKILRHLVTPPVGHRASSFDEYLHLRTQTPKCSVWIFGPVSSLLISCPLFSRLRSFLNDPRPRVEFRPSPRPMVSEEYTRLQSVDSRSCSPVLVLKESERRCLQAPPTFVLPCRRLFLPHLTHLPCACSRPPFRGSSGAFKVEGEWGGRARHKQQAQCTYVCLTQERTRSTDIATELRRSDDVSVEGTSVEGLMRETSLTSLAPSPSRQDKKVTFAKLLEKMSKEMSSSSSDVSCAEDKSPSRIFNFGSVRRSPRRSPRIRHTQRYSGSGSEDVIETPDISSSEMTPDPPKRLLTVKSSSSPCSKTSSPQSRNKLHKISSADSLLAMFRNFGGHFRSSLGVEPIESARVRGRRLLRAPSPSTTPTTPQKALPQVVKQDTLTVPGALQVQVQCAGGLANSSGPVITLEVPNADQYRCLSPITELPTPVPTPVPSPLPTPCRYRPKPRTSSESNDNKDSEDTESEFSLSISVERSSSDSSGPDHRVFFTPTRNLHSLHHCSPHRSETLSPTGATLTPSSTMSSRTPSPDTSPTISPVSSPKIKVKPPPLTIPNANVLEFNPEKPSTSRDPACGEISLQVPVIKVDSVDDGTRWDSTPRTRSQSVDVGSILQAPLITISPAEEEHPSASTSSSQPPLIIPTLNVTLASPPALKKQYPPVPTISIEAPEPPKPPEVPIRRHAPVIREKTGSLELQPAPAITITNTLTDAESDTDSPTGTCRRGGPPSCYLSPFLGVDLRASESNLSSSGYSSAYSPGPSRCSSNNPLLPDEPMTPSVSSIPSRPMQIPGPPPAVTAPPRTKRRPLLKTPPTEVSPMPLPAPLVRTDSETTDDPAASSQPEADSALELDTNDECSDGVAHGVEASKLSGVDEAEAQRQRLLMSSSQSFPKESPRLTRSPPSIVVHASLQSESSLEDCLTDKPSRLSPVSSRSESPISDSRLSVARIYPAFFGVSGKPELPYTDSDGLYDCPSSEVLNSDCHASASPLKRLGRKRLKRTSGKGIKSFLGLGSVGSGEGCSGASAAPAQSEGAKSRLEPPHWERSPRRLSPKRRVRAQTSVDLLSSSNESITSQSPVGSSPGEHGSQTLEVDQGRDGGPVGGRGRRRRPLLRGESIPGKHLTRQGSIDASGEETQEVSGSPVGIPRLEHFTALFPATCTTRGHCRYSLPTCSHCLLSCHLHQLRLYWPLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZH1</accession>
    <name>A0A423SZH1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002545">
        <property type="protein sequence ID" value="ROT69617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZH1"/>
    <dbReference type="OrthoDB" id="6372342at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="407" mass="43812" checksum="0F49DDEE5FFA8B40" modified="2019-05-08" version="1">MEESPQHILVKRDYCPNTFDPLGYIAFLMIGFQLTLNIREAEKQVQMQQAQESGAGTEDDAAEPLQQQAQPGVPGAGRLRGGEGRQGASAGDGEEVGRRRTAGEAAGGKRAEVYFSTSRRGGLLGPVPRLLLPSVMYFGVRVVSLPVLAVVGAADVLSPGEDSTLLWDRASPPPSVSHARSGLEFPDGVVGRASSYASCPKQSNFSYFGFMNMMLIMLETLAKGVRKYDRAPPADEATDSAVGGEDSDANHAARGEGRRSRGQRGVQEQSSPGMRSAPHNGCLCSPHDEENDPDTEDLLLEEHDPWSLLSTIDGGRKGAEGRRGVGASVKAMAGWIGWLMTSQHCLAWLQCEIRGLLVGYLGQNGDEDGDIDERVLKTCMHKHTKCPLLMLSHNNGSRSVLKIKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0C0</accession>
    <name>A0A423T0C0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative oxidoreductase yjhC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002503">
        <property type="protein sequence ID" value="ROT69891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0C0"/>
    <dbReference type="STRING" id="6689.A0A423T0C0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051450">
        <property type="entry name" value="Gfo/Idh/MocA_Oxidoreductases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377">
        <property type="entry name" value="BILIVERDIN REDUCTASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43377:SF2">
        <property type="entry name" value="BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00560)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT69891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="234" mass="25688" checksum="AB45B92DF5BCBDDC" modified="2019-05-08" version="1">MGNKKCVKLSSFGSLHHFRKEKKPAGGGTRCLQCPIETKCPYSAKKIYLDPAPTKPRWPMSPVCDIEDGPGGYLANLTKALETGPYGKCVYEVDNDVCDNQVVNFEFSDGATATLTMVAFTEHLCSRKAIVYGTHGQLTWDESKGHFVEHYDFLSQSTTIHESDVPPPLNWGHGGADYFLMKSFVEAVAAGDKDCILSGPKVSLETHLLTFAAEESRLSGAIVKPSEDPRWAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2D4</accession>
    <name>A0A423T2D4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycoprotein 3-alpha-L-fucosyltransferase A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002401">
        <property type="protein sequence ID" value="ROT70660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2D4"/>
    <dbReference type="OrthoDB" id="427096at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="44714" checksum="096AE1E7E869F909" modified="2019-05-08" version="1">MSFRLSSDLAWLGSCQSIRRRAKLGLAKGSHPKPRLLLVMGRLWRFLRSWRLRWGLVLVLCGVGVLNLLRPFDQGSRVSTRILMVHSSGGSARESALPRLRTPAADGSTRRKVIVLPRLQGHGELTSPPAVNKELSLGVKEEENSAREDANAAHEIHSGEPEIQPSGRRAEEDTKDEEKTRKEQEDIEMSFHQLPPQQGEDGAASWRNLSADELASLSVLGRRMYLGERVGTPKARNFTILVWKTGRSVERRLLKQYGKDKKDPFADCSVRNCDVTYEDAAASTADSLPSWSTCTQKGPQTSDEPHQGLAALGDLDDRDESPYHHLLVAKDQGPQPLNGYFNWSMSYRHPATRSRALRKDHQTRRRRRTKRQRRLFQYKIQDRGHHGIELRRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T5D8</accession>
    <name>A0A423T5D8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative epidermal growth factor receptor kinase substrate 8-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010046</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002272">
        <property type="protein sequence ID" value="ROT71633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T5D8"/>
    <dbReference type="SMR" id="A0A423T5D8"/>
    <dbReference type="STRING" id="6689.A0A423T5D8"/>
    <dbReference type="OrthoDB" id="4680325at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035023">
        <property type="term" value="P:regulation of Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11764">
        <property type="entry name" value="SH3_Eps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000183">
        <property type="entry name" value="Epidermal growth factor receptor kinase substrate 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039801">
        <property type="entry name" value="EPS8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055093">
        <property type="entry name" value="EPS8_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035462">
        <property type="entry name" value="Eps8_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041418">
        <property type="entry name" value="SAM_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12287:SF23">
        <property type="entry name" value="AROUSER, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12287">
        <property type="entry name" value="EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22975">
        <property type="entry name" value="EPS8_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18016">
        <property type="entry name" value="SAM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="321"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="253"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="384"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="607"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="656" mass="74351" checksum="01C12193A9F3A14D" modified="2019-05-08" version="1">MVHTGAPPAAATAMEGSRAVERARLAYQRMMRTEMMRADSEVRGEARGPRSERSSVSHNDDVSSTSSEKYERDHTAAATRELERRRRSRKSKKKDIGDGLLSMRAKPPPEREFVDIFQKFKLSFNLLAKLKSHIHDPNAPELVHFLFTPLALIVDASRDSNYGPNLPAKVLSPLLTADAIDLLTNCLTSRETELWQNLGEAWCVPRSMWKYNVPPYQPVFSSGWAPELSESERHSEVVSDGKRVREGRLRSDEYGSDFYDSDRREASPPPPGRYYGHDRPRSMTPPSEYPQAGKSDISQDSMDQPTFEKHQRQWLNDLKSRGAKIVQVTYPRTANNDKELTVVRGEYLEVLDDSRKWWKAINARGQVAHVPHTIVTPYAADQDSKEDYRAGAQRSAPPPVWKGKKGYGSNESSDEDAAGSRKKNSTIPAPPPPPPPDFTPSNSVAKRTPKPRPNNANQMYATTKSNVDMMNEELKLVLESFRRQRPHLDIQKTPDVYIYQTSTPQEVQKWLEMKGFSKRIRKQFEGVDGEKLFALDRDQLIIHCGKAEGIRLDSQITIQRNITGYKTARSSELRQILAQRRNKVEADKTDAKESITEDFSFLRDYDKSGYQTDSESDDEDMEVPGASGGLAGTLKEQIKKQRKKIQNQALDDKASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6K3</accession>
    <name>A0A423T6K3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative extensin-3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002200">
        <property type="protein sequence ID" value="ROT72129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6K3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="610" mass="66441" checksum="E8EEAE0880162FA1" modified="2019-05-08" version="1">MKESTLCRRHPCEDVRIYRMEPRQTCDTGKKQQGKDPLCPKTPPVKTSRSTLHEDIPVKTSGSTLPEDTPVKTSSTLPVKTSGSTLPEDTPVKTSGSTLPEETPCEDIHSARHPCEDVRIHSARNTPCEDVTHSARRTPCEDVTIHSAEDTPCEDVRIHSARRHPVKTSRSTLPEDTPVKTSGSKTPPVKTSGSTLPEDTPCEDVTIHSAERRRLHSARRHPCEDVTIHSAEETPCEDVRSTLPKTPPVKTSGSTLHEDTPCEDVRIHSAKTPPVKTSDPLCPKTPPVKTSGSTLPKKPPVKTSGSTLPKTPLIHSAEHTPVKTSGSTLPEDTPCEDVRIHSARRHPREDVRIHSARRHPCEDVRIHSARRHPCEDTPPVKTSGSTLPEDTPCEDVRIHSAEDTPVKTSGSTLPKTPPHPVKTSGSTLPKTPPVKTSDPLCPNTPPVKTSGSTLPEDTPCEDVTIHSAEDTPDPLCPKTPPVKTSDPLCPNTPPVKTSGSTLPEHTPVKTSGSTLPEDTPVKTSRSTLHEDTPCEDVRIHSARRHPLKTSGSTLPEHTPVKTSRSTLPNTPCEDVRIHSARRTPCEDVRIHSARRHPCEDVTIHSAKTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7B5</accession>
    <name>A0A423T7B5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_009253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7B5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="478" mass="52977" checksum="5E4472E6DB29A4FC" modified="2019-05-08" version="1">MSGQGASRDGAVAGHLVQWRPHSLTPSHNPSLTPLPYPPLPLPPFHTHSLTPSLPLPSIPTPLPLPYPLPYSPSIPTPLLPFHTTPLTPRLPLPYPPSIPTPYPPSIPTPLPPFHTHSLPPYLIPPIPTPLLPFHTPLPYPLPYPQSTLPYPPSIPTPLLPFHTHPLAPSYPLPYPPSIPSLTPLPYHSPPSIPHSLTPLPPFHTHSLTPQSTRLTPFHTHSLYSPSIPLPYSPSIPTTLTPFHTHSLPPFHYLPFHTHSLTLPYPPLTQSLPYPLIPTPLLPFHTHLPYPQSTPPLPPFHTHSLTPLPYPLPYPPVLPLPYPLPYHSLTPIPTPFPYPLPYPPVPTPIPPFHTHLPPLPYHLLTPPSIIHSLIRLPYPLPYPLPYPHPLPAIYPALTPFSSSLPFPSPLHYPPSLPTPLPPSLPPFYSSFLLSPSLPPFYSSFLSFSFLLSSSLLSDPFPYPYSHTTFPYPFLIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7C6</accession>
    <name>A0A423T7C6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cuticle protein AMP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009262</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7C6"/>
    <dbReference type="OrthoDB" id="6343684at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF173">
        <property type="entry name" value="CUTICULAR PROTEIN 47EF, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="18920" checksum="9221EC2B8C6E8EF1" modified="2019-05-08" version="1">MKLVSRGSPRGSATARRNLSKDLKEGPLTLPKLLSRDAGRLDDNTLLVCLTGIVAASALPQFQDRHPEHTAETVLDEREDRGDGNFRYRFETTNGINAEKVGTPGSEGQSNMQGAFSFPLPEGGVAQFSYIADENGYQPSSDLLPQPPPLPAHVYRLLEIAEQQRAQGITFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7F3</accession>
    <name>A0A423T7F3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL34</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L34</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009233</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002165">
        <property type="protein sequence ID" value="ROT72381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7F3"/>
    <dbReference type="STRING" id="6689.A0A423T7F3"/>
    <dbReference type="OrthoDB" id="277449at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00349">
        <property type="entry name" value="Ribosomal_eL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047868">
        <property type="entry name" value="Ribosomal_L34e_arc-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46595">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="119" mass="13493" checksum="18920B7D653BE9F6" modified="2019-05-08" version="1">MVRLTLRRRLSYNTASNKRRIVRTPGGRLVYQYVKKRGKRAACGNCKRELAGVVRCRPYELKRMPKYKKKVARAYGGSLCHTCVRERVVRAFLIEEQKIVVKVLKAQKAAAAAAGGSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCS4</accession>
    <name>A0A423TCS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Low-density lipoprotein receptor class A domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007217</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001915">
        <property type="protein sequence ID" value="ROT74284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCS4"/>
    <dbReference type="STRING" id="6689.A0A423TCS4"/>
    <dbReference type="OrthoDB" id="2019384at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="308" mass="33477" checksum="0C56215CF6E51563" modified="2019-05-08" version="1">MVGTSELVCYVLFQCLGTDVCAGKLICEEGRCIPPSLCCREKDLHPPNCTIRPGIECCKQLLHPAIRDQDLYYLKAPPRLHQQRNPQPDSTLIMGCIVAVANLITVGIIVGVRYHLWRSNGSTSRAHYHLNRLRSATLRPFGFGSSLSPPSTTDQYQLRSADTLYSRRIPGLRSDLLSPEILREQRQQCTHQQRPFTGGVVLCPPTNAQPPQYSQLPTAHTGPPPAYHQVVGAPPPPYSSRDDLTLGNSSDGSSLSLLSPLLNNNNNGDINGNTTAHLSVIQNQNVAHAAASSAAPSQFSGSQSRGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEE1</accession>
    <name>A0A423TEE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001841">
        <property type="protein sequence ID" value="ROT74833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEE1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="234" mass="25154" checksum="345A22208776FCD6" modified="2019-05-08" version="1">MVKGGGGGALLKRGGRSDDIGTRAINTITLFAQRWGFETDDGTSFASSKQDGSDESRQEDSRDEVERGRAEGDGGGCPSLQPVGSSAELIETRLAMGQEKDIFSPVNQLKFEYLKFGQNLPNCLENQTHLYKSRRIFWAISSWSVKLAKPLAKEAPAVLGFLANRLAGKPPLRGIMERDLRPSASISASAHLPLGRRLRIRHDAPRPARPDGDAGGLARPALGSLGLFSEGSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFS1</accession>
    <name>A0A423TFS1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001799">
        <property type="protein sequence ID" value="ROT75217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFS1"/>
    <dbReference type="STRING" id="6689.A0A423TFS1"/>
    <dbReference type="OrthoDB" id="9994289at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13160">
        <property type="entry name" value="PTB_LDLRAP_insect-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051133">
        <property type="entry name" value="Adapter_Engulfment-Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11232">
        <property type="entry name" value="PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11232:SF57">
        <property type="entry name" value="RE46159P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14719">
        <property type="entry name" value="PID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PID" evidence="2">
        <location>
            <begin position="68"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="238" mass="26857" checksum="B4462F43365E54D9" modified="2019-05-08" version="1">MRQLNHDSAVPQLPPKMSMSKAPAPPPASEITKEMRKLSFEDKESRNNKDVKQQPQEQPAALPLPQEFVVKYLGRRDAGGLWGIKHTRKPVDDMVARAKEMKPGETLPFLKMTVSEKGVNISEMPQNVNKNFEGGFYNIDVISYGVQDLVYTRVFAMIVVKEEAASIAKSQHPFQCHAFVCDSRHNARKLTFALAQAFQQFSKEVKANKSTRKPKKFAIDLRSPEEIEVDLKEADSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ84</accession>
    <name>A0A423TJ84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cornichon protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_004910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001653">
        <property type="protein sequence ID" value="ROT76493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ84"/>
    <dbReference type="STRING" id="6689.A0A423TJ84"/>
    <dbReference type="OrthoDB" id="434393at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="145" mass="16783" checksum="19693295DC122D86" modified="2019-05-08" version="1">MAFTFAAFSYILALIIDAFLIFFAIFHIIAFDELKTDYKNPIDQCNSLNPLVLPEYALHLLFNIFFLMAGEWFTLALNVPLIAYHINRYRNRPVMSGPGLYDPTSIMNHEVLSQCQREGWIKLAFYLLAFFYYLYGMIVSLISAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJY5</accession>
    <name>A0A423TJY5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004657</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001614">
        <property type="protein sequence ID" value="ROT76743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJY5"/>
    <dbReference type="STRING" id="6689.A0A423TJY5"/>
    <dbReference type="OrthoDB" id="446890at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592:SF78">
        <property type="entry name" value="GLUTATHIONE PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12326" checksum="3DD540588979082E" modified="2019-05-08" version="1">MPEIIEFVTTEYKVEFPIFNKISVVGEHADPAFKFLIETSSVVPDWNFYKYLVDETGQVIGAWGTRTLVEDIFDDIQAAVKKVKAKQARSAGGKQKVDKKESETPKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMP3</accession>
    <name>A0A423TMP3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003609</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001490">
        <property type="protein sequence ID" value="ROT77713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMP3"/>
    <dbReference type="STRING" id="6689.A0A423TMP3"/>
    <dbReference type="OrthoDB" id="6361951at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050373">
        <property type="entry name" value="Fibrinogen_C-term_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020837">
        <property type="entry name" value="Fibrinogen_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143:SF458">
        <property type="entry name" value="FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19143">
        <property type="entry name" value="FIBRINOGEN/TENASCIN/ANGIOPOEITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00514">
        <property type="entry name" value="FIBRINOGEN_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="2">
        <location>
            <begin position="46"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="19564" checksum="D37FD1A7EEFC37AF" modified="2019-05-08" version="1">MRHSCVPLPRLARRGCDRLLRPGDRRRRLDGVPEAAQAPCEGGLLPHEMRVDLTDYEGNATWAKYGLFHLGDASTKYRLQVGRYNGTAGDGFGGGRHNGHPFTTHDNDNDAADANCAARYRGAWWYDKCHISNLNGFSYEGEHETYADGIEWQPWRGYRYSLKTAAMMIRPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNP4</accession>
    <name>A0A423TNP4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003251</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001444">
        <property type="protein sequence ID" value="ROT78047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNP4"/>
    <dbReference type="OrthoDB" id="6366342at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="357" mass="40083" checksum="FBD63E9AF19AA17C" modified="2019-05-08" version="1">MALGRGLLWGFSGPCVLLLLLQLGVLAEGRIYQKRRMSEIETFRQGALEVCVEPFSQRARVDLRLKVMNRGSAKVVPVGIVSLRKNQLSDGAQHTVTANHFVEEGEHKMIVLVDGTYTPYEKTQVYAPSDEYVFYGFSISLRNGMGRQLTGPTENDDMTFDDPSEEVVPSVEAGTESTIQTNATSEREEWWDFVWKMGNFKGVPVLLLLIVTLIVGLVLGALCTLCCEVYFSRRRDVDKGHEVDRKFSNYTSFRPDYYPRLSTTTTLTSTLNNARVDNEANHSNPLSQCPPPSPPCSSPADTYSMPHDAHRERAGSVSVHDETLPLNYPLTYPDRDPQNSKLLHTFGGQSYRESEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRG0</accession>
    <name>A0A423TRG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_002254</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001301">
        <property type="protein sequence ID" value="ROT79038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRG0"/>
    <dbReference type="OrthoDB" id="8194276at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019274940" evidence="3">
        <location>
            <begin position="33"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="15193" checksum="6C691CE3055D55FA" modified="2019-05-08" version="1">MSRSSCRRAFLTFSSCSFQAVILVCLVGVAMCAPQLQQRVELIEEPLDTPDPYAFSLNIADDETTNYHTRSETQDENGVVRGSFSYVAPNGVRYITTYSADPINGYQANTVEEQTNIVIVTPKPFDQKQQQVGVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTR8</accession>
    <name>A0A423TTR8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dystonin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001184">
        <property type="protein sequence ID" value="ROT79856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TTR8"/>
    <dbReference type="OrthoDB" id="6357129at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030056">
        <property type="term" value="C:hemidesmosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005882">
        <property type="term" value="C:intermediate filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045104">
        <property type="term" value="P:intermediate filament cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042060">
        <property type="term" value="P:wound healing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00176">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000001">
        <property type="entry name" value="Microtubule-actin cross-linking factor 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000039">
        <property type="entry name" value="Short stop, isoform N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000040">
        <property type="entry name" value="Short stop, isoform N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.60:FF:000042">
        <property type="entry name" value="Short stop, isoform N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043197">
        <property type="entry name" value="Plakin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018159">
        <property type="entry name" value="Spectrin/alpha-actinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002017">
        <property type="entry name" value="Spectrin_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23169">
        <property type="entry name" value="ENVOPLAKIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23169:SF23">
        <property type="entry name" value="SHORT STOP, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00435">
        <property type="entry name" value="Spectrin"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SMART" id="SM00150">
        <property type="entry name" value="SPEC"/>
        <property type="match status" value="30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="24"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1074"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1160"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3374"/>
            <end position="3394"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="199"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1838"/>
            <end position="1888"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2088"/>
            <end position="2126"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2633"/>
            <end position="2663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3061"/>
            <end position="3095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1084"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3559" mass="405597" checksum="119EE4F156FE2258" modified="2019-05-08" version="1">MDPDALACPAYASRESALTPVAVVHATGVTSSWQLEIRRFGASLFDLHLTRDQTGAEAVDAAEKLKRQYERCIALWQKKQLRMRQNMIFATIKVVKSWDLAQFIAMGAEQRNAIRKALNEDAEKLIQEGDPNDPQLRRLKREIDEVNRLFDEFERRAAEPKPGAVLSDQCSSLKEYLDMMEKTLIQRCLAAIPRDLDLLEQLVIEHKQFENDLSSHELEVESIQKNYQNLTRRTPAIQRQVESITQQWDRIWALSHVYIERMKCVEMVVTGIEEGTQVVSEVELKLAEHQDLPDELDDLERVHQELLDIQQIVQDHQVLIDRLLEECRNVRTLVVKSRPSQKIHPDVDRLEEDVRKLRMRWENICSQIIERLRSCEAACELLTKYRNGHDVEKVDLSDFETGLRNQKIEDLGPSEAELELERLRQAMIEKYKQCDATIVDMMDQVSEIERRLAEQEPVSENANGLRNQINTVKAIKDELDEMFRPLGTCLDGVRQVVNQGGDALSREELESLDMAATRLKQRYDKCVDQADTTHRRLTTAMEEFSKYEKEIALFQTWLMQATKTLIEKERLCSDLNKIKNHEQGCRDFLGDVIAHQADLRFITMATQKFLDESSVYLRTVNNFRTSLPERYPVLQADPDSVVRDAADDVTAEFKDLLARANKLVDKVTSVGNKQRDYTESIEKAIRWLKDTDVKITRILQEPVGAEPKSVQDQLDKTKAINNDVVAQSRLFDNCRGTAAALLRALEGELDANERDAIERPPEELYERYNELADRLAHRCQELDTALVQCQGVQEGLDSLMAWLSSIDLQLKNASKPASLNRDRLDEQVREHRQLHADIMSHQASVVQINDSAEALLSSASNARVAKKIETKLRELNTKFEKVVERSESRGHHLEVVSTQLEAFTVSVEHFEEWYIEIVEVVESREVLSLDVESYARKIDEIARQRDARTGDFDGMIKTGKELVSKKDVTDTAPVKDKIKNLEGQWKELNDTLDERARNGKERSEQLLAYEQLRDRCTQWLTTTENILDNAQAVGLETEIVKRQHEELKPLHKEFREYASTIDKLNELGNAYDALLRGERPESPTRRRSSVTPAKRPSITSPLKSPDMSPIQKELMQVNNRYEMIGMRLGDRQNDLDTMKEELKKLSDSIRSLNTVLDKAERSMPRDAVPTTKEEADKHNRQCKSIQDDLLEKQPALDSLKSQVIELIKKRPTAPGADILQDQFDLVNDRYKELQGRLKDRLSFLEHTKDFLDSHDALNNWLNSKDKMMTVLGPIASDPRMVQMQAQQVQVLRDEFQAQEPKLNDLNDAGDKIISVCEPNSMAGKKINDKLDAINNKWTELIGQLDARDSALNAASDASTDFYNNYNKLHDTLLKLGEDFDEVSASGADSAQQIQAVQDLEKGLERVRAPLIDLEGLGEHLVSILSDPSSKSDIKSKVTQLNKMFNNLERKLGNRKSELEASLRDEEMFGQSCQDIQEWLADQVAHLKDKLLVSADRDILSHQVSDFEPVYKDLMAKEHEVIMMINKGKEIVAKSSRKDLNRQLSSTLDAIKNEWDNVRKTAVERRSRLQKCMDTCNKFHNMQEKFNPWLDKAEDKARNMDPIAFTKKAIDKQIKEIQAFKNDVSRHSGEFENNKTAGDKLVGCTDTDHDGVHDALGIMKERWDNLNAIVMARAQDLDDVSATLADFNEKARDLDHTLQRCGDKLASLDTLGGGGKDAKSLERMKALLDETNALGKQVDHVRQKGEDLCTAADSAGSDATHIQDEVERLSDRYGDLKGKLEDRCHDLEEASQAVNQFGALVKNVGQELTALDDEIDRMAPVGRDIKTVTGQIDQLQSFLTKVDQKADEIEDAKAALEDLVAQGFTGSNNRTAEDQIKQLGRQLKKIQDRCDVRGKDLDTVLNKLENFYQKYNVVMEEINETDKEGEAFKPVGADVDTIIAQQEEFKRFKGKHIEALGKQVTECNKLGQGLIQSAASGVNTHDLEDDIDGMNDLWNKLKEMIGNREKALDKGLMQSGKFQDALDSMLQWLGNFEEMMENQAPISGEYSVVKAQAQEQKFLRKMLLDRQNEMQALLSMGRSLAADLEPSEKANVEGQLDDLLNRFDDANARSQERMEALEETLKVAKEFQNKLNPITEWLDRTEKKLKEMSTVPSDEEKIQKLLDEHDNLHDEILGQKPAFDDLTDVATALMNLIGDDEANALADRLQSTTDRYGQLVEDSEALGRLLQESKVGLRHLVLTYEDLLSWMDEMEARLSKYRILSVFVEKLLEQMDELTDLGEEVVSHEKQVSEVMEAGSQLMKHISSDEALQLKDKLDSIQRRYNDLSAKATDLHKSANEALPLVQQFHSAHDRLGSWMLSVEGQLQSMDSSGQGLLEEEIERLAQEIQEHRPLVEAVNLVGPQLCQISPGEGASNIETLVTRDNRRFEQICEQIQRRMERIHMSKQRSQEVTHDIDELLDWFREVEGQVREAEPPSVDPDEIRIQLKEHKALNDDVASQKGRVRDVLSNAKKVLREAPQHEDTSELREKMDDLKETMESVSKLSSDRLSTLEQALPLAEHFFETHHELDDWLSGMENEAMVMDTPALRAEQIIRQMERNKNFLQSIADHKPLLDKLNKTGGALLKLVNEEDGNKIQDLLESDNDRYNALKNALRERGQALEDALQETSQFSDKLDGMLSALAETADQVKNAEPISAHPEKIHEQVQENNSIIDDLDRKETAFTAVKAAAEDVINKASRNDPAVKDIKNKLDRLNKLWDHVQMATTQRGQSLEDALAMAEKFWEELQGVMAALKDLQDTLKAQEPVAVEPQAIKQQRDELSQIKTKIDQTKPEVEQVRQTGRDLMNLCGEADKPEVKKNIEDLDYAWDNVTALYARREENLIDAMEKAMEFHDTLRNMLEFLEKAEDKFSGMGAIAGDIEAIKGQINQLQKFKDEVDPHMVKVEALNRQAQELKERTTPDQAAAIMEPLGEVNRRWDELLKGIVERQRDLEYALLKLGQFQHALKELLVWIERTTKNLDDLKPVFGDPQVIEVELAKLKVTINDIQAHQSSVDTLNDAGRQLIEADKGSEDASNTQKKLSELNKKWSELQDKASSKQNDLETALREAQIFSAEIQDLLLWLGDIDAALSTSKPVGGLPETAKEQLLRFMEIYDDLEENRSKVEGTLQQGQEYLKRSREGSASNLNHSLRTLKQRWESVMNRANDKKIKLEIALKEATEFHDALQQFVDWLTEAENFLNGQQPVSRVLDIILQQIEEHNSFKKDVTAHREVMLNLDKKGTHLKYFSQKQDVILIKNLLVSVQHRWEKVVSKAAERTRSLDLGFKEAKDFHDNWNELISWLTDAENTLDELASNVGNDPEKIKAQIAKHKEFQKALGAKQPSYDGTMKQGRSLQNKAPKTDEETLKQMMADLKNKWNSVCQKSVDRQRKLEEALLFTGQFKDAIQALLDWLKKVEVGLVEDGPVHGDLDTVMALVEQHKAFCAEMKNRSAQVESVRRTADDLLVKASAEDAATIKTQIIELVSSWEKVEKATEVRTLRLEEALQAAERLHKVVHMLLDLISLHTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUC2</accession>
    <name>A0A423TUC2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001161">
        <property type="protein sequence ID" value="ROT80067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUC2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="487" mass="52018" checksum="85819D0C0CDF3881" modified="2019-05-08" version="1">MSRCEHANSPQAKLSCRLEDSCDRTMICIQMVEALLGALSSAPTLKAVRIISVYLFLEREGDFTVRGCSSDSSLQRCLARRRAPASLPSPASSSTPEQVTLFHPFRLLLSQLPPPRPRPFHSFRLLLLSIPSASPAPPPLPPVPPAPPQHTCSSSAFPLPPPRPRPFHSFRLLLLSIPSASPRPPPLPPVPPAPPQHSLCLPRAPAPFHSFRLLLLQHSLCLPRPPPLPLVPPALLSIPSASPAPPLPPVPPAPPQHSSASPAPRPFHSFRLLLLSIPSASPPPPPLPPVPPAPPQHSLCLPAPPAPSTRSACSSSAFSLPPRAPRPFHSFRLLLLSISLPPRAPAPSTRSACSSSAFPLPPRAPRPFHSFRLLLLSIPSASPAPPPLPLVPPAPPQHSLPPPRPPPFHSFRLLLLSIPSASPRPPPFPPFRLLLLSIPSASPAPPAPSTQALSPTGPRKKVPTRKEDCHCEISRLEGLAVARARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TV83</accession>
    <name>A0A423TV83_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001135">
        <property type="protein sequence ID" value="ROT80292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TV83"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43907">
        <property type="entry name" value="SLEI FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="837"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="892"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="849"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="991" mass="109975" checksum="8368B9ED4761C826" modified="2019-05-08" version="1">MGAPCAEALQLPSSLHRTTPPLASKELPPCFKKNSPPLLQKNSPPCFKRTPPLLQRIPHPLASKELPPLLQRTPPLLQRNSPLLLKKNSPPPCFKRTPLASKNPPCFKELPPFASKELPLAQRTPPLASKEPPLASKELPPLRFKKKLPPCFKELPPCFKRTPPLPFPPCFKRTPPCFKRTPPFASKELPLCFKRTPPPLLQKEPPASKELPPCSKLASKNSPLASKELPPLASKNFKRTPPFASKELPLLQRNSPLAQKNPPLLQKNFPPLASKNSPPLKKLPPLLQKNSPLASKNSPPLLQKNSPLSKELPPLNLPPCFKRTPPLLQKELPPLASKELPPPALASKEIPPLLQELPPFASKNSPLASKRTPPLASKELPPLLQKNSPPCFQKKLPPLLQKKNSPLQKNSPPCFKELPLASKELPPFASKELPLLQKNSPLASKELPPFASKRTPPLASKNSPLASKNSPPCFKRTPPLASKNSPLASKETPPCFKRTPPLCFKRNPPPCFQKKPPPCFKRTPPLASKELPPCFKKNPPLASKELPPLLQKKSPPCFKRTPPLLQKNSPLASKELPLASKELPPCFKELPLLQKELPPLASKELPPCFKRTPPLASKELPLCFKESPLASKELPPCFQKNSPPLLQKNSPPCFKNSPFASKKKSPLLSKRTPPCFKRTPPPCSKELPPFNFKRTPPFASKRIPPCFKRTPPCFKRTPPLLQKNSPFASKELPLLLQKLFKRTPPFASKELPPFASKELPPLLQKKLPLCFKRTPPLLQKNSPLLQRNPPLLQKNSPLLQRTPPCFKELPPLLQKNSPFASKELPLCFKNSPLAQKNSPLASKEPPLLQKNSPLASKNSPLASKTPPLASKELPLLKTPPCFKRTPPLLQKKNSPLCFKRNSPLASKKRTPPASKDSPFASKELPPCFKRTPPLLQKNSPFASKELPPFKKLPLCFKKNSPLASKELPLCFKRTPPLLQKNSPLCFKELPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW77</accession>
    <name>A0A423TW77_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Vitamin K-dependent protein C</fullName>
            <ecNumber evidence="15">3.4.21.69</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Anticoagulant protein C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Autoprothrombin IIA</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Blood coagulation factor XIV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_000564</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>Degradation of blood coagulation factors Va and VIIIa.</text>
            <dbReference type="EC" id="3.4.21.69"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.69" evidence="15"/>
    <dbReference type="EMBL" id="QCYY01001089">
        <property type="protein sequence ID" value="ROT80686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW77"/>
    <dbReference type="STRING" id="6689.A0A423TW77"/>
    <dbReference type="OrthoDB" id="10012881at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007599">
        <property type="term" value="P:hemostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000011">
        <property type="entry name" value="Coagulation factor X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0356">Hemostasis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="20">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00040219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT80686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="184" mass="19595" checksum="C6796C3BF9847815" modified="2019-05-08" version="1">MHDWNNGPTRIITRAADRIVVHPSYNTNTLDNDIALVHIKDKVSFTNWPGVKPVCMPPLNADFSGRDATATGWGTTSSGGTQPEVAREVTIPITTRSECQAVYGSSVTQNMICAGLLQGGKDSCQGDSGGPLTVEEADGRHYLAGVVSWGSGCALPGRYGVYTDLPNYVNWIDSIATTGKYCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4K6</accession>
    <name>A0A423U4K6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_023192</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tom70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000660">
        <property type="protein sequence ID" value="ROT83624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4K6"/>
    <dbReference type="STRING" id="6689.A0A423U4K6"/>
    <dbReference type="OrthoDB" id="66418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46208:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="41"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="133"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT83624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="18141" checksum="D0F9CCF1BB1D8449" modified="2019-05-08" version="1">MALSKYTSNATGIPKWQIALAVGGTVAATAGIYYFLIRDSSKKGSQTKTQSKKSRDSTVSGGSPANEAESAGKADDAANLTPLEKAQACKNKGNKYFKGGKFSEAINCYDQAIEMCPPENTVDLSTFYQNRAAAYEQQHSHPEALSRPSAPGIPNDEVAEGKEASGSSSIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5M7</accession>
    <name>A0A423U5M7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022807</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000609">
        <property type="protein sequence ID" value="ROT84018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5M7"/>
    <dbReference type="OrthoDB" id="6085115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019569889" description="Ig-like domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="117"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="43210" checksum="2AB7AF941CEE18EC" modified="2019-05-08" version="1">MNSPNPTPNMSRSISFWLMLLPLVAPGLGLSPTTLISQVTVSQLLEEVSKLLQAEKPSNAPTARTQQVPEMLPCTDDPEMEDCTKVVENDLCIAGSFYARYCRRSCILAGKIPADEPHLHQEAEADLVMNMTSEKDRYLQGSDITVSCFATGYPAPEIYWLLNASEISSEKRYQENVTDFGGILSRTIRSVITVTNYTGGGRVELACCAINRVHFATRSKWLKIDRAEINVYPEQPVFKSTQEALVTCVIKGIDPGNVSWNLGHSLGQEPHTVVDSRWEENGMTVVQSNVTIFAAQLSTIPKTFTIKCSSTNENYRDLGVIKDVYIIKDVEIPNNCTDSNSKMCFSRRRMCNAVMQRNCCKTCTLMSNAEREHSFSSGSGPPRRVCDPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U739</accession>
    <name>A0A423U739_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endothelin-converting enzyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000533">
        <property type="protein sequence ID" value="ROT84499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U739"/>
    <dbReference type="OrthoDB" id="7867452at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="2">
        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="120" mass="14094" checksum="B0F8177277EF6CAF" modified="2019-05-08" version="1">MSHHDLMLQGNLDPESLPCDDFWTFSCGGWLEDNPLPPTRSKWSVKEKLKHEALAEMRELLDTMDEPQDVNSIEWKLKTFYWSCMNVHSYMKSGLDLIKRKIITELCVRVVMEPYTNDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7B4</accession>
    <name>A0A423U7B4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000520">
        <property type="protein sequence ID" value="ROT84613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7B4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="571"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="753"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="845"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="879"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="920"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="962"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1146" mass="121834" checksum="DF9E2D7097905880" modified="2019-05-08" version="1">MPQCHPVPHAPSTHQCPIHHTSVPHPPTHPSAPSTTPCAPQCRAIHHTSAPSTTSITTAVPGPIHHTSAHPPHQCPSPIHHTSAPSTTSMPHPPHQCPIHYTSAPSTTPVPHPPSASTSAPIHPHSVPHPLPPVPHPPHQCPSAPSTTSMPHPPHQCAIHHINAHPPHQCPSTFQCPIHTSAHPPHSTTTQCPITKLPSAPSTTRAQCPIHTTPSTSPHPPHQSAPTTPVPHPPHPPPPPVPPPHSAPSTTPVPIHHTSAHQYTSGPITTTSTTPVPIHPPVPSTTSAPYHNQCPSTPVPIHHTSAPSTTSAPSNHTSAPSPTSHPHQCPIHHTVPHPPHPHPPPAPHPPHQCPITTPVPHPLNAPSTPSSAPSTPPPPTPVPIHCPSTTSTPSPHPSTTPVPPSTISAPLPHPLQFHHHPSAPSTTSTPSPHQCPIHHHQAPPLHQCPIHYTSAQCPHTQCPNPLHQCPIHHTQCPIHHTSAPSPHQCPPSPSTHQCPIHVHSAPSTTPVPPSTHTSAPSHTPVPHPPHSAHPPPVPHPYISAHPLPHSAHPPHQCPIPPHHTPVPIHHTQCPSTTPVPHPHTSAHPPHQAPSTTPVAPSTTYQCPIHHTSAPSTTPVPQCPIHHTSAPSTTPVPHPPHQCPSPHQCPIHHTSMPHPPHMPHPPHHAPSTTPVPHPSATPHQCPIHHTMPHPPHQCPIPIHHHQCPIHHTQCPIHTHPPPHQCPHSIPTPVPHPPPSAPSTTPVPHPPSMPSAPSTSAPSPHQCPTTPSPIHHTSAHPQHQAHPHTSAHPPHQCPIHHTSPITTPVPHPPHQCPIHPSIAHHHTSASIHHNPVPHHHQQCHPTVPVPHPHQCPITQPVPHPPPVPHPPHQLPHPPHQCPIHHTSAPSHHHTSAPSTTPVPHPPHNAHPTPVPPHQCPIHHTSAPSTTTMPPPHQCPIHTPVPHPHTVPITTPVPHHHTSAHPPHQCPSPHQCPIHHTIATTPVPHPPHQCPIHHTSAHPPHQCPIHHTSAPSTTPPITAPSTTPEPHYCHAKHNLSLPLVVLTSFPLAEPLPSAPLLPPLTSPTAPEPTYGRPRDAAPRATYESVVAVKGGLRRGRASVAVLLLERWRCLCGSWGCGLQASSLHPAPPSCPLLSDTFAPQITQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9E8</accession>
    <name>A0A423U9E8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ribonuclease kappa-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_017115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000317">
        <property type="protein sequence ID" value="ROT85312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9E8"/>
    <dbReference type="STRING" id="6689.A0A423U9E8"/>
    <dbReference type="OrthoDB" id="67317at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056552">
        <property type="entry name" value="Ribonucl_Kappa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026770">
        <property type="entry name" value="RNase_K"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31733">
        <property type="entry name" value="RIBONUCLEASE KAPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23489">
        <property type="entry name" value="V-ATPase_su_f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="94" mass="10483" checksum="D064AE46FD1585AD" modified="2019-05-08" version="1">MMKICGPKLSLCCTILSVWAIIQLGLMAIFFYVRSPAFIEDLKIDDHDHHDAEKFLKALDTSYSTIAVNCAISAGLYVVTLAVSGWQMWVNKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAE0</accession>
    <name>A0A423UAE0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate sulfotransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000224">
        <property type="protein sequence ID" value="ROT85643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAE0"/>
    <dbReference type="STRING" id="6689.A0A423UAE0"/>
    <dbReference type="OrthoDB" id="5987729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="50874" checksum="63A1507A5E187FD5" modified="2019-05-08" version="1">MDGDLTEFRCQRNKLSFKINAFLGRVPEKLELGALSERNLRALSARLRVAAVGHPDGNKMFHSPTQMACQKRDLRLRSDGKSDKIRSALFRSLASHGEVSRSSSSSFSLECQRDGGDGQRDLEEEDNRTLRLDQGRRGPVGTQENPLFVLILSSLPRSGSTMLSEALSTLPGSVLFFEPLWIQEKEGCIREEGCVADFLMNAFKCTYEDAFEEWLRSKTLFFDFFHRDVRKCAYESKENKERCLSQIDVRAMCRGAPVRLMKVIRARLAFLETYVRDADNFKVIYLTRDPRGSLNSIARFKSWNQDPHERCQSLEDDLATYELFSEIYPSKVFHVKYEDFCLHPENKTSEILSFLTGNHTIPQGLRDYLAEHMSRRRGNRNMSTFKESRTEFQAWRSKISEDLLRKVESEPACANSVLKMDHRLFRSAKMARDLNIPLFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UB02</accession>
    <name>A0A423UB02_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Major facilitator superfamily domain-containing protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_004444</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000159">
        <property type="protein sequence ID" value="ROT85889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UB02"/>
    <dbReference type="STRING" id="6689.A0A423UB02"/>
    <dbReference type="OrthoDB" id="6360775at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328:SF28">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="550"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="573"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="711"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="691"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="717"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1062" mass="115511" checksum="CEAFBCDF936FB6F7" modified="2019-05-08" version="1">MTSLRLSPCICLLQQRTSGYIAQPHKRIRRPLPNTHKGTARKIRKTALDSNAWEGRARLAKTRESAEDAKMALSRRIKFGYGVGHVLNDLCASMWFTYLLVYLQYVLQLDRGLSGFLLMVGQVADAVSTPLVGLQSDRGCSISNYGRRKTYDLCPRLLPIHLHRVRHLLRSSWLRLRAPVGLHDLSLPVRLGFHSSLSPRSHTGLNRLEGGKGGTELNQRVTLPVCAAARVISAYLSMTRDTTPAARGIPHSPASSLDSEDDPLVQPRSGPRERSPTACRSVKGSVGGTPSGIGEDRASRQGLPPTLRLPLGDCASFRQIPACLGPHLASSPRKLIVSESLQGSRVTPSGPLACSTAQGRPSLDGRRSRRYVFDVCSDVLVYLVAWVAFSEDSFEERFIDPSDSDKFKSITLTILVVGTIFSVVFHVMTPEDKSGRWSRDDEAEVITQEAGTAQTSAGDAAEGDRVRRPRLQMTWRDWLTEPQFYQVSMLYASARLVANLANIYMPIYLQETVHAKETMIALIPLVMSLSGVGASFLLRLLRKGIGKKPATVVGIVVGLVASTVSALPWMPSWALFSVAVLWGVSGSLLVILSLSFAADLIGRSTDSSAFVYGSMSFGDKVLNGVAVFMIQELTRVACEGPNCSIYYRHVMSLGIFIPLILSFVAICLLSRVKLGRTRKLVQAQQDEDESSVSSVHSDSSEILLSPGTSLEREAKSGVTTQPDTTQRQPNNKATFFVSLSAWRLTSEEMPVAWPAPSPTGATAPVPVPAVTSAVAHPPPRSPSPAMWKVLLVALPLVLVPCRATGPLEQVAEQSTHTGDQETMNTEEQRFKYLLYQISGTVQKLMTEQQKYIDNRFDTLTLAMEMACSSHAVSQVNDRVDVAETGIDMENMAAEIVRILTAVLQSQLSSLATSGAVSDLQSNLSSFASSVTEEVKQAISSLTSEIDTKSKSVATNSQIQEIKEQLASVTACSHRKDFDQVLALLTTTEEDIDDLEESLKTSLAEQKAACLGEDEHQERTASLVQLLESLQVSVNSNADSIRSVASAVGGLEGEWGPRGPRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LQX4</accession>
    <name>A0A3R7LQX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative carboxypeptidase B-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_020151</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003863">
        <property type="protein sequence ID" value="ROT62026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LQX4"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03860">
        <property type="entry name" value="M14_CP_A-B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF91">
        <property type="entry name" value="FI01817P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018738486" evidence="11">
        <location>
            <begin position="23"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="85"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="381" mass="42628" checksum="1EA760F418A3D878" modified="2019-04-10" version="1">MMSTVPFVIVATVTVIVATVSGKESSRHEILRGHQIWQLSNDVGDVPLEVMQKGLLDVLGHFGTSKKVRVPFHCLEEAQRLLQEKGVSREILVEDLATFLEDHERLSKRLTSIGKSFENRDLWMVHVRPNDPSDSEEAGAVWIEAGIHAREWISPAVALHILKELVQDNGSIGNFDVYVVPMANPDGYNYSFTSDRLWRKNRRITSQPGCGGVDLNRNWDFHYGVGASENECSEVYRGSEPFSEPETKALRDAMTKVKDQLKVVMSLHSYGQQLLYPWGYTKHKTAPDTSDLIARGKVFADAAKSVHNTVYKVVNSAGDLYKASGATDDWAKGVLGVKYTYTLELRDEGMSGFNLDPSHIVPCSEEVWEGLKALLYEISKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LS83</accession>
    <name>A0A3R7LS83_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PC4 and SFRS1-interacting protein isoformX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004091">
        <property type="protein sequence ID" value="ROT61585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LS83"/>
    <dbReference type="STRING" id="6689.A0A3R7LS83"/>
    <dbReference type="OrthoDB" id="62853at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05834">
        <property type="entry name" value="PWWP_HRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12550">
        <property type="entry name" value="HEPATOMA-DERIVED GROWTH FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12550:SF70">
        <property type="entry name" value="JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="50140" checksum="5F67A1F1E7FE5805" modified="2019-04-10" version="1">MPKSDVFKAGDPIFAKVKGYPHWPARIEPYEEDPSGKPLKKYPVLFYGTYETALLKPDDLFPYSTHVEKFGKPQKRKGFNEGLWQIVNNPSLDPSIPIPPDVSSASLPGTPKTPAAKPGRKSLSVTPAVTTDVKSEESDEDVGDLVIDESAGKGAKPGRKRKRQDSDIASETPAKKAASSDVKKTPKETPKQTPKENKQSKLVAKETPKETPKQQSGESLEPQVSRSGRLIKPKKFLDEGEDASRPPSAAAGTPSTPVPVAEAASTPSITKTSNAVKSTPSAPVTTPRKRLSLSGSEEVAPAESPAVPEEMPTPTGPPPKKRGRPPKNRDIDNSPKKAPAAAPPSESPAQETTSKMSSPPTKALADVKQEKKSPIKESRSSKKSQLKQNEIELPKELLFVVPESQEWDSMFAEKVAEFDDACHRSGITEESKISLVRDPTHHIDGPQEEASKRGKENTSPLTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LX00</accession>
    <name>A0A3R7LX00_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003086">
        <property type="protein sequence ID" value="ROT65424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LX00"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018748341" evidence="1">
        <location>
            <begin position="24"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="41525" checksum="DDF1B999C5B24088" modified="2019-04-10" version="1">MCFPLRFPLALSLLLSPVSFALSLSFPCFSHIFSLFPSCFDHLVTFLKLPLPSSAERRALLTTSADPLPPSGPFLIFFFHPSSLLFPSPPPFSFPFPPPSHFLLVLLFSPPLALLYDLPSLFLPPSFPLTSFSPLPPYSSLPLSLLSFPLPLPLSSPPPSPSSLPFPFLSSPFPLPFFSPLSFPPFPFSPFPFLPSHLPSLLPLSLSLFLLPSPFLFFPPPFLSVSSPPFLPPSHSLSSPLPSLSTPPFLPPFPSLLPSFPSPLPSLTSPFPLLSPPPSFPLPSHSPPPSLPLFFLLPLPPFPHSLPPSFSPLLLSPLPLPSFPLLPPFPPSLPPFFPSSLPPSLPPSFPSPSSLLPPLSFPSFSPPPLLPRLPPPFYRHYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M635</accession>
    <name>A0A3R7M635_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002080">
        <property type="protein sequence ID" value="ROT73024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M635"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF444">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="46932" checksum="0A10FFCB18D6D477" modified="2019-04-10" version="1">MPLPPSVSSSTRGRANDSNGSSSRVRLSSTNQSPHTCRPTLVGAPLIYSALTEFPALSKSINRLPNHGTRSATTSRLTVPCPLSLVARPRQMSQRQGGVRPHEAVRDHTPFQQPMGRPLHLVKKDGDWRPCGDCRHLNTGNRPRQIPAATPALLHELSGCTVFSRIDLVRAYHQIPITEEDIPKTAVITPFALFEFLRMPSVPQRHSDLPRFMNDVTRGLEGVFIYRRHPRRQHLRGRPRPSSPRPLRQTTRSRGRDQPREMSLRRSFALFSRPHPSPLKASPSAGEAPQALHALITPNRASRNTKIKWTPLQTKPSKPARKPWPPPPAEPLPEAPLSIAVDASDTAIALSSSNDRPYVEAKEFHILTDHKPLTFALHSRTRRQSLARSATWTTSHSSRRTSVTFGRGQRGRRCPHRGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6G7</accession>
    <name>A0A3R7M6G7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013423</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002667">
        <property type="protein sequence ID" value="ROT68425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6G7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="497" mass="52274" checksum="159FFA9F3B881E99" modified="2019-04-10" version="1" fragment="single">MSPSSPALPPFPLLLYSLLSLSSLLLLLLPLLLLMPPTLPLLHFTPSSPLLLLCLLLASPLLSPLPLASPSYLPLSHLPPPSITYLPSPLASPSYFPHLPPPLLLTLSSPTCSPSPTCLPLYYLPPLSHLPPPTYLPLPPPPLTYLPSSPLLPSPTCLPLLLPLSPLPLLLTFPPSTTPTASPLPLPLLPLASPLPSLLPPPLPLPLPPISVPSTSSSLTHGHLLTVGFYDVHFPFSSSPPPPLLLLLLLLLLLLLFLLLSSLLFLFLPLTSPPTSSPPPLPDIHFPYSSFLLPPPPSSSSPFSLSFFPIPFTINACICLPLRSPCLPPSPLPSLLSLPSPLPPPSSSSPPFSLPPPFSSLASPSSPPPPSPSLLLLSPVLIASFICQSLPAAAHEYFVWLRRMPLTPPPFPSSSLLLPPLISPSPPPPSPSPPGSLPLPPPPPTGSSLHRLPPLPRLPLSPRLPSLSPGSPGSLPLSPRLPPARLKLIPSSLSGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M975</accession>
    <name>A0A3R7M975_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">xylose isomerase</fullName>
            <ecNumber evidence="2">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006003</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M975"/>
    <dbReference type="STRING" id="6689.A0A3R7M975"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48408">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48408:SF1">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0859">Xylose metabolism</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="21541" checksum="0FB68D1331985B95" modified="2019-04-10" version="1">MNKYFPGIGRIEYRPDAGPDDTLVFRHYNPSETVHGRTMEEWMKFSVCYFNTFRYLGSDDYYGERTHQRSWEDASRSLDNYKRRMLANFEFLQKLNVKYYSLSDRWQRKKMAPEGESFDETNGYLDEMVTLAADLQKQTGIKPLYYSADLFSHPRYMNGAGSNPDATCSRTPAPRSSAAWTPPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9H2</accession>
    <name>A0A3R7M9H2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005744</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001744">
        <property type="protein sequence ID" value="ROT75700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9H2"/>
    <dbReference type="OrthoDB" id="6366928at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902495">
        <property type="term" value="C:transmembrane transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF1">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018602910" description="Ion transport domain-containing protein" evidence="8">
        <location>
            <begin position="22"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="37342" checksum="1FE2ECAC98233A27" modified="2019-04-10" version="1">MGRFFCSCSSWRLWLPSWSWCEDEFCRVNKKPDELTTAVNSTSSVQEANATSLRPLDVGEANATSPRPPDVAEGVDSWDSSQSHFCHAVLCISLIFQIVLEANYIRKLRCQYVNITSLVSFMCIILCVVLLLPTSVCSLQHGIKSVPIWQCGIIALVLASFRLISTINRLPAFSVFTSITQSFIMSYLKGVMYVLAIIFLFALIFHLLLSNLLSFVTLPQALVKMVVWMLGDLGYDDTFINNTLNYPYLVNCLFLVFLFTIGVFLVTLLKAPSTDINKIKFYRMARQAQMYFTIDISFPSFKRSHAIGKFCDKEHRVLDRLQARENIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAL5</accession>
    <name>A0A3R7MAL5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003838</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001514">
        <property type="protein sequence ID" value="ROT77518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAL5"/>
    <dbReference type="OrthoDB" id="6364363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="86"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="479" mass="50617" checksum="B92FA86B7734508A" modified="2019-04-10" version="1">MQNEDYPKEIPVSGAAFAQPQQGYGAPAPPQPSSGYSYGAPDLRASASNINNQQEQDPIAALAANIPGGGVPGEDYPILASVPDTGFSCEEQQFPGYYADTAPEAGCQVFHICQFDGRQDAFLCPNGTLFNQQYFVCDWWFNVDCAASQQFFSLNADIGKIPDNAAAASDASLAASYGAPPAPSRSYVTPATPLSPTAPSPRPFSAISPPLRLLPPFLHGRSPSLPAHLELLPAAADAPFVPFPAPSPAYRLPVTSTPSVGRRERPRPPSPSLPSTAGSSESHSPELSPVPGSSRHSRLRGRGSAPPAWKPPGILVPMQRLATESRPPLDPEGANAERPQSPPRRQPNPEIYFPPVTTTPSPLPEPAALRNMPANATLMIPSFARASGNPPVAALRPRLASPDVALGRSVFPEGTPVSPGSPRSDSSLVVFRAPFEAALSARISSHLPQGVRDTILLNIRHRLLLYLSAGHDAPVLVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBJ5</accession>
    <name>A0A3R7MBJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CUB-serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009371</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002187">
        <property type="protein sequence ID" value="ROT72253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBJ5"/>
    <dbReference type="STRING" id="6689.A0A3R7MBJ5"/>
    <dbReference type="OrthoDB" id="9977936at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="23140" checksum="AE4A858B54E96A4C" modified="2019-04-10" version="1">MTTSDYVLVGDHNLYSGSEANSQWMQIAEIKNHPSYDSNTLDNDIALIRLKTEIQFPSDNKIAPVCLPTAGEMYDSVDATITGWGAQQEGGSTSGTLFEVTVPTMTNTVCNTKYGGRITDNMICAGIPEGGKDSCQGDSGGPMVWKNGKWKLVGVVSWGYGCARPDRPGVYARNTLTGFRPRPEVSVRRLVNPPIGKVVRSQSPGQEYTLEGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC29</accession>
    <name>A0A3R7MC29_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_009035</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002133">
        <property type="protein sequence ID" value="ROT72578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC29"/>
    <dbReference type="STRING" id="6689.A0A3R7MC29"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901029">
        <property type="term" value="P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000002">
        <property type="entry name" value="Putative ADP/ATP translocase 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="209"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="113"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="210"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT72578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="309" mass="33428" checksum="BCA405EF47DF4782" modified="2019-04-10" version="1">MSKGFDPMSFAKDFIAGGIAAAISKTAVAPIERVKLLLQVQAASKQITADKAYKGMVDCFVRIPKEQGVLAYWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKKTQFWRFFVGNLASGGAAGATSLCFVYPLDFARTRLAADIGKGAGQREFNGLGDCLVKIFKADGLGGLYRGFGVSVQGIIIYRAAFFGLYDTAKGMLPDPKSAGIIVSWAIAQTVTTISGIISYPFDTVRRRMMMQSGRKGADIIYKNTIDCWRKVAKNEGTGAFFKGAFSNVLRGTGGALVLVLYDEIQVLLFGTKSGGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCQ8</accession>
    <name>A0A3R7MCQ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001389">
        <property type="protein sequence ID" value="ROT78385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCQ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12135" checksum="BA6AABF16164A11A" modified="2019-04-10" version="1" fragment="single">LDHASVVRLYVVEVVGLVASLPCLAAAVVALLSAALAARAACPPKTKTQTPLVLYLPRWGERGYGMNEQTIIQSGARSPPPLPPAPPTSPPANHRDDRANSPPPSYNQIAEESYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MCX2</accession>
    <name>A0A3R7MCX2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002064">
        <property type="protein sequence ID" value="ROT73097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MCX2"/>
    <dbReference type="OrthoDB" id="6356761at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="32979" checksum="E7D7DB420D520C11" modified="2019-04-10" version="1">MVFTSDIQASYWTCHGLDQLASLRQVCVSDRKPSTTVPQLTTYNTLHDYVQVSCGIPALSLPNFVGLVALSASVPGAAAALRGASVRRPAEPASTAVPQLTTYNTLHDYVQLSSAAPSAPLVPSSSIPASYWTYHGLDQLASLRQVCVSDRKPALEMEFRVPVLQLEKGPGMNFYLLTSADQKVLLGNRIKSEVCCSDPVETVTVSRPPDVKIGTVEGHGKNFALKNASGDTLCSLEMEDRGCCDCSEKIYQVVPSSAPHSQGSVEICCDGCKITFPSAMDVISKALLICFAINLLYSIEEDRKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFH4</accession>
    <name>A0A3R7MFH4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Actin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_006497</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001826">
        <property type="protein sequence ID" value="ROT74964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFH4"/>
    <dbReference type="STRING" id="6689.A0A3R7MFH4"/>
    <dbReference type="OrthoDB" id="6331703at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT74964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41912" checksum="D2AA7D7792960F3E" modified="2019-04-10" version="1">MCDDVDTTALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDTGDGVTHTVPIYEGYALPHAILRLDLAGRDLTAYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFESEMNIAASSSTLEKSYELPDGQVITIGNERFRCPESLFQPSFLGMESVGIHETVYNSIMRCDIDIRKDLFANNVLSGGTSMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILSSLSTFQAMWITKEEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFK3</accession>
    <name>A0A3R7MFK3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA-binding protein MEX3B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000024</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001002">
        <property type="protein sequence ID" value="ROT81198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFK3"/>
    <dbReference type="STRING" id="6689.A0A3R7MFK3"/>
    <dbReference type="OrthoDB" id="427410at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22424">
        <property type="entry name" value="KH-I_MEX3_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16518">
        <property type="entry name" value="RING-HC_MEX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000013">
        <property type="entry name" value="Mex-3 RNA-binding family member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000012">
        <property type="entry name" value="Mex-3 RNA-binding family member D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047226">
        <property type="entry name" value="KH-I_MEX3_rpt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047227">
        <property type="entry name" value="MEX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23285:SF7">
        <property type="entry name" value="LD09246P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23285">
        <property type="entry name" value="RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="1 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="512"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="396"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT81198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="562" mass="57506" checksum="1537FBFEA9E2F638" modified="2019-04-10" version="1">MQEEEGGGGSCKIKALRAKTNTYIKTPVRGEEPVFVVTGRKEDVGMAKREILSAAEHFSQIRACRKNNLNGSMAPGPPTNVPGQVTIQVRVPYRVVGLVVGPKGATIKRIQQQTHTYIVTPSRDKEPVFEVTGLPESVEQARKEIEAHIAMRTGGLLDQDEPNAAAAARHHADFPPPTHGLDNLFNPPSSELVSSLYKLNNSSLNGLASINGIANSAGLNGLTNGLSNGLSSGSSLNGINGLNSLSGSGLNNSLNGMNLNNTLNSLNTLNQLNDLNSAFTLLGGDTGSSLLGSSNKGGSTLDSSLFSSFSGGVGNTKLGSDVSGSGSGGLGLYGVDEGLGSLGSSMGSSPSFDPAPPSIWGELSRPLGNNMSSTVSSSSSLSSTFSSLSSTLSSSLTRRSSSVSGASPPSSRLSPSLESHPPARRISSDPAPGLAAAPSLASLNSALSGGLGGLPTSSPSSSSPASTPDLTQQLSAFQSVPGLTSAPATSTATTTIASMNGLMNGMDEKKRCVTCCESEVVAALVPCGHNLFCLDCANKLKSEASECPICRMKVTHAIRIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGL8</accession>
    <name>A0A3R7MGL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative serine/threonine-protein kinase ATR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000884">
        <property type="protein sequence ID" value="ROT82098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MGL8"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012993">
        <property type="entry name" value="UME"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08064">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00802">
        <property type="entry name" value="UME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UME" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1073"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1312" mass="145108" checksum="0C7FCA168A79668D" modified="2019-04-10" version="1">MADDVSGNSQNTALRDKFVSVVGPVFEGGEEANILTLLTSLANVCRHDEGLVVTAPVNITNVNEANGHKSSKALECDKTSEFTCWLIAELVTVEGSETVNKANVNLQVTIMRILATRSPLLFSGVMADYINIGLEGKEVLFEGGTVVCQCFSSVIRRNDAHPVPKTITFVDDSKLDRILTTIIMVLSQLGSFIDQYCWQMMDRVWLLICSCLEGGDEKLKVAALGAVTVLIDSCSVPKSNERLDYLMQCVGALLSGVLDESGSGENTGKIIKDLPGTHQQNVQKEADNILPEHLAKVIHVLLQHIPFFLPIFQEEMLQKTSICLQKAEGLKKIPETLRAELLKCHCVLLDALTSSPCVQDAQEAMYLCAEENIMLKEVSKFILKRIVVRDLLEALPSHAIQSQQQEISRSQSRKRRLSETESAQPTISVVTISKLWKQALQTMGNVLSDWTDGTSALDLDHVKALGEIICTAGRVITNIPNAQVTLQFFPDSWVTVAADSLATIMAEADNVNIVLCLMETVAYMTWTGSVAESSNTKPQNNHMWLALATLPWMASEVSLLDLKPPNAKQYTSWASRLKWGNNSRVKAISISIIAIMPENIAPKWRCHIMRAAINERDSVVMHEVAKWFPVMVHQLGGAGGQQLVGEVVGAVLHFPDNKTIQAGAASLTHLLCSLLNHTTVKCPQSEDDTYGPNILVCRVCKNANSTNILDAQHVDPTLVSRFLGLLTHSDTKVLVSIVDALPAVISHTKLNPQMINQYISLLDHQDKQVVSAMCRQLSELVCQGVQSDSSQDLKSAVVSKEGELVLSYLNELFKTAERKKSSSKTYLAVLEALHYLVRCPLGGLTGGVLVLLLRCLAISDRLVTAQAHLIIHSLANTLGLPLKDLYIRHRQSLAQVLSEIVKPGEVGAMLSHVAEVFEWNTSSTGSTRKQGKSNVGQFIISQIRHLLPALAVRATQEAKPGLLQELAGCLSLRLRDILIDHFQHILAYLVFHYPQEEQEAVLDFIASTTDIHIQNIRRCSVQNQVNELILGLHDHRDAVLREFSRMRAIEQNSDHNTSSRLTRKNTMESKFSHDPATSRDIAEYLAPRLLGILGFLDSKLVSSSTMYKEKRCALWSLSDLLVVMGRQYISPVSRKILASLKTALKLRDDEFFDIGCSAWTNFLYNLDESTLEGLLEEVAVVVKPLVKERPQQMAPVLTSVLVEMPSIRPLLGNLPLLPEDPALTQVNQAILERQTRVMGGSREEVVSALSPVLRGLSHESLDVRLHALSRLRYILRHNQEAVHHLTTDADTVHPTISELFSILLGNEIIYYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MID8</accession>
    <name>A0A3R7MID8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004012</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001537">
        <property type="protein sequence ID" value="ROT77341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MID8"/>
    <dbReference type="OrthoDB" id="6337372at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="237" mass="25214" checksum="25CF3FFFDE5374DA" modified="2019-04-10" version="1">MEITVATLALLMVLCFSVPAVVGGCCLVYIILRKNNRTQPVRPHSTPSSNDVASPEPLLERHEGTTVLPSPQRTPFGTSRRMGADLKASFGSTSSSLGRVMDGVTLGTALEGVILLHSHLEELRLQKAFMESFVRSGGMGHCSDVSRAFNGSLRDFPTSPTTLAPSAVLPWSHSIADVHKSSSEMVLNASGPDSLRFWPVSSSCKSLSRAPSSRSGGDGLPFWNASSTCTSTPVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKF9</accession>
    <name>A0A3R7MKF9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cuticle protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000427">
        <property type="protein sequence ID" value="ROT85152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKF9"/>
    <dbReference type="OrthoDB" id="6355773at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF196">
        <property type="entry name" value="CUTICULAR PROTEIN 72EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10351" checksum="63E169D3024DF182" modified="2019-04-10" version="1">MATRQLLDGGQHELSDEIGQYSFGYAGGPSSRAESRDAFGVVRGSYNYVDSEGKVQTQHYVADALGFRASGTNLPVAPDAPLAALPAPSPNPSRTLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MM13</accession>
    <name>A0A3R7MM13_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016808</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003116">
        <property type="protein sequence ID" value="ROT65228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MM13"/>
    <dbReference type="STRING" id="6689.A0A3R7MM13"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000013">
        <property type="entry name" value="Carboxy-terminal domain RNA polymerase II polypeptide A small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040078">
        <property type="entry name" value="RNA_Pol_CTD_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01124">
        <property type="entry name" value="C0.1:_RNA_Pol_CTD_Phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="7">
        <location>
            <begin position="79"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="4">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR640078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR640078-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="275" mass="30999" checksum="9ED7B85A1B06E11D" modified="2019-04-10" version="1">MLSRKTRFAKTYLLFAGSQNGKKPKRSIFRTLFCCCVSGESDSGGSANGVCVSEDVSPYTHLQPPTGPQRHLLPAVSHRDMHKKCMVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPYVDDFLQKMGELYECVLFTASLAKYADPVANLLDKWGVFRARLFRESCVFHRGNYVKDLSRLGRDLHKVVIMDNSPASYIFHPDNAVPVSSWFDDMSDSELIDLIPFLETLSKVDNVYSVLRNCNNPLNSQPPPQNQGSQVLPQIKYDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSC2</accession>
    <name>A0A3R7MSC2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative collagen alpha-2(IV) chain-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002654">
        <property type="protein sequence ID" value="ROT68603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSC2"/>
    <dbReference type="STRING" id="6689.A0A3R7MSC2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1082">
        <property type="entry name" value="COLLAGEN TRIPLE HELIX REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="34072" checksum="955938EAD8950E1F" modified="2019-04-10" version="1">MDGARGERGLPGADGGVGPKGEPGLGGAPGLVGKPGVVGLPGPEGPRGPPGAEGIKGTTGKRGEPGMPGEPAPPGQPGPQGPPGVAGPRGEEGPEGPPGPPGPQGPTGNPGQMGIIGAKGHPGLPGLKGEPGKSGKRGEPGPMGGVGPRGPAGPQGPPGRPGKDGAKGSSGIQGIVGPRGLPGPIGPPGLLGPAGPPGLPGFQGKVGAPGPPGPPGPPGESAPVAIQVDGERTYSLPGPMGPTGSPGMPGVRGADGERGPQGKNGNPGLPGPAGPSGLPGPPGQRGSPGNPGMPGSPGREYSEAELRSICSSVLRVPPPPQWHSIPRLDTPPPPCPIPLTSPHSLPAATATIAISIYQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N3L6</accession>
    <name>A0A3R7N3L6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005013</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001666">
        <property type="protein sequence ID" value="ROT76400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N3L6"/>
    <dbReference type="OrthoDB" id="6371549at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006631">
        <property type="entry name" value="DM4_12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07841">
        <property type="entry name" value="DM4_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018576209" evidence="1">
        <location>
            <begin position="26"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="19644" checksum="4C40575777B35C2E" modified="2019-04-10" version="1">MMRASAVLSAALAVVFLAQIGDVESAPCCGRRRGGALAVGALAFAGGYAIGHHKSHHHHGGGGCCNSCGGCGKKRRSIEAFLEDPKIRETYKEIAAEDKDECGLRLVCELAQKDPQGLAPDERQILAPYRGAGASDGSAYGAYDEAAWRGKEGRGCAASYPLCAFTAQQIMQEYRKYVSSNETVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N5X0</accession>
    <name>A0A3R7N5X0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA-directed DNA polymerase from mobile element jockey-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003178</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001429">
        <property type="protein sequence ID" value="ROT78115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N5X0"/>
    <dbReference type="OrthoDB" id="425681at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47027">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47027:SF20">
        <property type="entry name" value="REVERSE TRANSCRIPTASE-LIKE PROTEIN WITH RNA-DIRECTED DNA POLYMERASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="85"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="42135" checksum="6FFA22757FF031A1" modified="2019-04-10" version="1">MDPPPIPWHLFDQLIALCSLRRMTSYSGGVTTSAIQQTILHMAQCPVLTSLDDLPTLEETQKAIKQLFKLVGEAMAVKLTELMQQFCEAGSVPQNFNDANVIHLNKNKGSRASCDNHRGISLLSITGKIMALNILNRILHHLLDDVVSESQCGFKSNRRTIDLIFALRQLQGKCREQNQNLYVLFVDLMKAFDTVNREGLWSILSKFDCPSNFIKIIRSFHNGMMARVVENGSVSDPFSVYNKVKKGCALAPTLMFATVLVSALSNTDAGITIHYRYDNPFFDLRRLKARAKVLKALMKDFLFADDCALAALREPDLQELFSCLATVDQAFGLTTSLRKTEVMLQPAPGFSPPEPNIDIEGTTLNNMDSFTYLGSCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NBH0</accession>
    <name>A0A3R7NBH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamate-gated chloride channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000801">
        <property type="protein sequence ID" value="ROT82586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NBH0"/>
    <dbReference type="OrthoDB" id="6365990at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1220.10">
        <property type="entry name" value="EGF-type module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="4">
        <location>
            <begin position="231"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="44248" checksum="331C1868CE398D84" modified="2019-04-10" version="1">MGACISRQKRCDLAIDCPDNSDELNCNPVIVPDGYHSELPPPGQPFELKTIVRIISVREFDLLHSKFVVDVAVHLLWRDPRLMYRNLQKDYGANKIKDPSQLWVPMIRVTDSTGSEVIIFDHLSALYAFRSSDPLPDDDGIIVEDDQLYSGHSNDLLYYQKSSLTAMCLFDLQMYPFDIQMGTGFDFKAHKRLMEYTVYKYTMDIFNENNKSTARVELHFQNLHVYYVINTFVPCLMMAVICFLTLCFDLEDFQNRITISITSLLVLATFFTQTSQSNPKTSYVKLIDAWYLAIICQDFFTIVALVFIEMKRLSETRGPNKRTEVMPLFSNREVREGDNSQGQKRVARNNSVALTFNRVCQGLFSTSLLCIVICFIMISVTYTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ND40</accession>
    <name>A0A3R7ND40_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="9">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_022853</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01000614">
        <property type="protein sequence ID" value="ROT83964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ND40"/>
    <dbReference type="SMR" id="A0A3R7ND40"/>
    <dbReference type="STRING" id="6689.A0A3R7ND40"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06615">
        <property type="entry name" value="PKc_MEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000115">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000100">
        <property type="entry name" value="Dual specificity mitogen-activated protein kinase kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050915">
        <property type="entry name" value="MAP_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47448:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STE7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="86"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT83964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="45142" checksum="5106B400A3D2A08C" modified="2019-04-10" version="1">MLNKNKFNLKLPPGSIEQNNDNDNHTGTDTPQRKASTGATGSFGNMSLESLLKCIQELDMDDTQRRRMEIFLVQKQQIGELNADDFEKLGELGAGNGGVVNKEKHKPTGLSMARKLIHLEVKPAVRNQIIRELKVLHECNSPFIVGFYGAFYSEGEISICMEYMDGGSLDLCLKKAIRIPEPILGKICSTVLKGLAYLREKHQIIHRDVKPSNILVNSRGEIKICDFGVSGQLIDSMANTFVGTRSYMSPERLNGDHYSVASDIWSLGLSLVEMAIGMYPIPPPDPATLQKIFGQKVEGVSPSPTSRSPRSAGLPGEPRPMAIFELLDYIVNEPPPRLPPGVFSPEFVDLVDRCLKKSPNERADLTTLQNHEWIKRAERENVDIAGWVCKTMDITPSTPTKPSAEGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NZJ9</accession>
    <name>A0A3R7NZJ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002324">
        <property type="protein sequence ID" value="ROT71238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NZJ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="902"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1189" mass="128605" checksum="D3AC16C322A72ECF" modified="2019-04-10" version="1">MFPGRQVSLPHTLPSFSLTHQRSHLSLTNLLTHLSIIKPPIHLSLFTSPRPFPISLQCTEPRLHSHSSFSLTPQPHILVLYSPSLSQLPPQPDPPLSALNAFSLNRPVRIRPPVLSASLPLSLSPFTTFPRSLFHFTKPPMSSPHSPSLTQVSLRLRVDRDLVRFPVAGVHVEGSSRQGGHGQREGQEGRRHSGAPPRPHSPSHFLTVFQSSILPPSQPHNFPPSQPPNLLFSLPHSLPIFHSLSLTLNFSSPHSLPIFHSLLPHSLPIFHSLSLTVFNLPFSLLTVFQSSIPSPTVFQSSILSPHSLPSSISLLTVFQSPSLSLTVFQSSHLSPSQSSNLPSSLPHSLQIFHSLSLTVFQSSILPPSIFQSSLLSPSQSSQSSILPLPPSNSLSPSNLPFIPLSLTVFQSSILSPSQSSKSPILFPHSLPIFLLSPSQSSNLPSSLPHSLPIFHSLSLTVFQSSIPLSLTVFQSSFSSPHSLSNLPSSLPHVFQSSILSPSSLPIFILSPSQYSNLPSLSPHSLPIFHPSPLHSLPNFHFLPPQSSNLPILSPSQSSIFHSLSSQSSNLPFSLPHSLPTIFHSLPFTVFQSSILSPSQSSNLPSLPHSFPIFHLSPSQSSNHLPHRLFPSSSQSSNLHPLSLTVFPIFHSLSLTSLPIFHSPPHKSPIFHPLSSQSSIFHSLSLHKSSNLPSPPHSLQSSILSPSQCLPKSSILSSSQSSNLHSLSLTVFPIFHPLSLTVFQSSISLSSTVFQSSILSSSQSSNLHLSPSQSSNFHPSPSQASNLPFLSLTVFNLHPLSSPAFPIFHPLSLHSLQSSILSPSQSFQSSILFPHSLPIFHPLSPQSSNLPFSLPSQSSNLPFSSPSQSSNSPFSLPHSLPISISLPHSLPIFHPSPHSFQFPSLTTSQSPILSPSPPPLSPSQSSNLPFSLPHSHIISLPHNLPISYSSLITVFTIFHSLSLTVFQSSILSPSQSSQLPSSLSLTVFQSSISLSLHIFQSSILSPSQSSNLPFLSPSQSSNSSILFSLTVFQSSILSPSQSSNLPFSLPHSLPIFHSLSLTVFQSSITVPPPASISSILSPSQSSSTSSNPLLPHSSLPPSQPHLFLPHNLQSPFSLPHIFQSSISLPHSLPIFHLSPSQSPIHSSPSQKTDRTGFGTFANYVRRRSSESGEEMIGLHRSSPGVFRIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P475</accession>
    <name>A0A3R7P475_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001826">
        <property type="protein sequence ID" value="ROT74982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P475"/>
    <dbReference type="STRING" id="6689.A0A3R7P475"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="49956" checksum="39F457A7656F1967" modified="2019-04-10" version="1">MSRSQTSGVKGQWERRRRHQRTVHSLSTSLKSVPGKHFLKNHSLLLDADLALGRPAPHSHPASPDETKLSGGLLSPCFRAGPGPTTQKYDPGKVRRTRATANAAPPRLTAIPPSLTLPSFLPHAPLFPSLTLLVFPPHAPCLPSLTLPCLPSLTSLSSPPHAPVFPLKISCLPPSAPLSSPPHASLFSLLTLPLFPPYAPLSSLLTLCLPPSTLPVFPPSPVFLPHAPLSSPLTISCLPSSRFPLFPPSTLPSFPSLTLPSFPSLTLPLFPPSRFPLFPPHPSFPPSHDAPCLPSHAPCLPPQDLLFPSHAPLSSPLTLPFSLPHASLFPSYAPLSSSLRSLSFLLTLPVFPPSRSPVFTFPVFPPHIFRFLLTLPSFPSTLLFSLLTLPSFPSILLSLFPPSRFPHAVFPPQLSSLPHIPPRTPSHSYTLPSQTFTFHPPSHFPPKLITHKTEQVNGFLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P609</accession>
    <name>A0A3R7P609_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001653">
        <property type="protein sequence ID" value="ROT76491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P609"/>
    <dbReference type="OrthoDB" id="10007483at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01217">
        <property type="entry name" value="PTB_CG12581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21219">
        <property type="entry name" value="FI19613P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21219:SF3">
        <property type="entry name" value="FI19613P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PID" evidence="2">
        <location>
            <begin position="12"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="633" mass="68255" checksum="B31FA9000C7A5EF1" modified="2019-04-10" version="1">MKMARRGGADPTPICRCRVLYLGSSVPQVTKDGLQGIQEPLRELYPAEGAVSARGIDSWLSVWSNGLLLENVDENQKKVTRFFPIDSLHYCAAVRYVVVSGGGDATVPRFLPLDSPFARNPNINHPPLFACIMRRTTGIKVLECHAFICKRETPANALVRCCFHAYADSMYARTLEGGNSQYGSVYGGRATEERAIEIEDFSSAASEIIPASVNSSPTQEAPASPTSQGSPGDEISIYNGDENHKVWAGPPKTETDLIYTEYNSGTMRSARSTSSLYGTAGGTRPARPRQMIMPSVAPPPPPEVDKDKKSKKDSKNKSRRDDDEMSRLTNGIPTRPASVVNGGPRHHNGSLPRHMNGHSSPPKGKGKFPRLLHGSSSLSDRRSKGMRGPPPFIMVQGPPGPPGPHGPPMPHGPPGPHGPHGPPGLHGPPGPHGPPGPHGPPGPPHMVPPMGPPMGPMPPPPPHMMPLQGPPPPHMLPPPGPHHAMLPPPGPMAAYGPPGPHGPPGRRPPSRVLEEPIYMPSTRPLSPTASYQPGHFPHEQYLLQQKGHLNERAFSYSIREEHRSRSYGSLAGLGEDSMSKKDREILQMVADLDLSGDELERVEPRPGVYRPPHSDRLSAAGTITSRISRASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P6P3</accession>
    <name>A0A3R7P6P3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative smad nuclear-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_004411</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001585">
        <property type="protein sequence ID" value="ROT76967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P6P3"/>
    <dbReference type="STRING" id="6689.A0A3R7P6P3"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="222"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT76967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="315" mass="36344" checksum="AEBDEFE80B268E2F" modified="2019-04-10" version="1">MLACEVTVVVCNRRGGRCYSGCVSLAMMILITSLREKLAFLESDNAHLRRRLQEEQCRALETEKAQSHLDIRKIMEAEEKLKQQVSSLSQREKEYASLMEELKSLQEKYEERENVLRIANERVGQASKLKSLHMESRGNVEEARAGVKMNAEDNVQEEEEVQKPNMGLSGKLTEDTNTYNGVVIKYSQPPEARNPREDGDECLPHRQRPQSCRHPTDHPSCSKQHAVLQYRLVTYNREDGTKGRTVKPYILDLESANGTYVNNRRIEPRRYVELLEKDVVKFGYSSREYILLHEGSKGEDRMRLIRVLTLAQCPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P7C0</accession>
    <name>A0A3R7P7C0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003512">
        <property type="protein sequence ID" value="ROT62976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P7C0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="675"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="739"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1245" mass="132856" checksum="30D691F6424EB009" modified="2019-04-10" version="1">MSRHWFQQPIPPPSLRPGSSLSLRALCASLFSASLAPPLLRSGSLTFSSASWLLHFLQLPGPSHSLRLPGPSNLLSASWGSLHLSPPPWLQSILSDSWLPTFSPPPGFSTFFRLLAPSTSSASLAPPLLSALPGSLQPFSRFLAPSFALAILAPPTFLRPGSSRFSPLLALTFSPPPWLQFQSGSCSSTFSQPPCSSTFSALPGSSNLLFRPPGSSTFSPPSLAPSTFFAPGFRLVCSWLYTFLRFPGSSTFSAHGSSLLSASLASTFLRPLDPHSIRPLLHSHASMAPSPSFALPWLTSNTSPPPSWSLTPLSPPPGPPPSLRSWLLHFSPPPWLLHLLSAPWPPPLLSASLAPSQLLSASLAPPPSSRFRAPSTSPPLVPPLSPPSRAPPFSPALLAPSTFSPPPGPIPSSGPPWSSIFSALPWLPPSLRLLAPPLLSLLASSLLPPPLALHFSWLLTSSALPGPPFFASWLPPPSRLSWLPHTLFRFPVLLLSPSLATRTFSPPSWLPPFSELLSPFRVLTILSAPWSFPFSRLSLGSLHLLSALPGSLHLLSASCPGSALPPSLAPPLLIVPGSLHAFSRPTLAPPLSSAARCPSPLRFPGPPPFCLALSPAPPTFSRFLAPPPSRPPVLAVLHLLSPFLLLAPFRLPGLPPLVLASSWFPPRTLCCVSTFLLSLYVPFFLDSFYVLFVCLFLQPFPGSVHFLSARSFLSLLSLPFTSSLHLPLALAYISSSSSLPLVFVLFISLSFYVSIHTLFFSPHLSLLFVPHHSSFHFLHSLTFFNSLSFPSFPPSLPFTHHPLSPFLLPPSTPLSILHLSPFPLPSLHSSILHPLSLLPFLLPPLIHPSSTPFPPSLPPLPPFIILQLSPPSFPPSLHSPSSTPPPSSLPPFLPLSPSLLPSLHFLHLSPFPPPSLPHSFLPSSISPFPPFLLHPPPPSPFPPSPPSIHPPSFIRSIHPSFPSSPSLHSSILNPLSFPPSSSLPPFTHPSFIAPPPTSLLSSSLPPPFIHPYSSFLLPSFSLHSPILFQFAPSSTSSFPSFPPSLHSPSSTSLLPPSSSLHSPIPLSFAPSSTSLLSLLPPSIHPLPLSFPSFPPSPLHSPSLFHSLHPHSLLSPSLHSSILHLSPFPSFPPSLPPFIHPIPPISNSPSHLSLSLLPSFPPSIHPSLSFMAFPAALTGTPGHVFLATLLSLDALLLSRAGCCALFWSFLSVLLVAPFDSPSGTLLTLGKNSGNTWALPVATLSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P867</accession>
    <name>A0A3R7P867_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001416">
        <property type="protein sequence ID" value="ROT78214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P867"/>
    <dbReference type="OrthoDB" id="6381192at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018704870" evidence="2">
        <location>
            <begin position="19"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="35209" checksum="26D8636A4BD11D5D" modified="2019-04-10" version="1">MKTAVMVMSVMICAVAAGGPTESQLLHRIQSREGRGLTQARRYVVKRDGTNRLEQAEAAPARASRLVLLLTKAGLEHARRRRAAQADPGVSEDPADRLAEDTPATEFQAATKEGPSADETTTVAEQGTKRKRRRKMRKILGVTARSGMLLRHGNNIVKVRRVKKRRKVPEGEIQGTQLRMGTAKGSGIEIRQGTAAMKGKASGQESAVQGESETGGNTNIQGQEGDGTEGEEDYYYYDGEDTESPGDGAEGQEGDGTEGDQDYYYDGTGGDGADGGDGTGGQEGDGTDGDQDYYYEETDPISHTTYYFAIDASAAVHAPSISADDLQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAN5</accession>
    <name>A0A3R7PAN5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003093">
        <property type="protein sequence ID" value="ROT65371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAN5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="490" mass="52439" checksum="3670A3E9AE5A0437" modified="2019-04-10" version="1">MTCLGRKEQYFKCDVGNSPLPPSLKNSILNATLATLPPQSEEKYLRLSLNTRNFCILPLPPPLPTSTNLPQPYSLPNTYPTAPYPPPHSSLPPPLPVPDTHPTVPYPPSLSSPPSPRLLITTPQTLILPLTLLPPLPPTLALIPPTPPYPLPPSHPIPFPHPPPHSPNPPYPFPPPTPTLLSPTHPHSPNPTPLSPNPTPTLPPLPLLSHSPTPPHPPTSPLQSPYPTPYPFSPHPTPPYPSPTPTLPTHPPTLPIPYPLHPTPYSPTPPPPHPYPLPPPPPHLLISPVPVSQFPLSSPHPNPPPLQPPTLPTPPLSPSSPPTHSPPTLPPLPSSPPPPPPTFSLVPLRFPPKIAPPSPLSPPQPPTLPSPPPHSPTSPPTPPYPFPPPHPIPPTHPSLPLSPPNTLPLTLSQPHPSPLPLLILPPHLLISPAPVSPQNRRGMSDSIAGQTMGFLSDYFCLLACFWLDLAWFISILACFGLHSLLVDGLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBU9</accession>
    <name>A0A3R7PBU9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial</fullName>
            <ecNumber evidence="7">6.2.1.4</ecNumber>
            <ecNumber evidence="7">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="7">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + succinate + CoA = succinyl-CoA + GDP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22120"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.2.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with an ATP-specific beta subunit, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with a GTP-specific beta subunit forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.4" evidence="7"/>
    <dbReference type="EC" id="6.2.1.5" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01004511">
        <property type="protein sequence ID" value="ROT60863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBU9"/>
    <dbReference type="STRING" id="6689.A0A3R7PBU9"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000005">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="10">
        <location>
            <begin position="27"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="301"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="323"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="399"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="490"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="599"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="617"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="656"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="719"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="742"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="781"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="832"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="850"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="912"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="933"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="974"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1085"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1126"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="7">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="40"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT60863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1250" mass="137062" checksum="892166C3066C3550" modified="2019-04-10" version="1">MDKHIPAIGAAPLGARSCYSASRPNLAINENTKVICQGFTGKQGTFHSRQAIEYGTLMVGGVSPGKGGQKHLNLPVFNSVSEAKSATGADATVIYVPPPGAAKAIMEAVEAEVGLIVCITEGIPQQDMVKVKHALLRQSKSRLIGPNCPGIIAPEKCKIGIMPGHIHQKGSIGIVSRSGTLTYEAVHQTTQVGLGQTLCVGIGGDPFNGTNFIDCLETFLKDPDTKGIILIGEIGGGAEEAAAEYLKEHNGGPEAKPVVSFIAGLTAPPGRRMGHAGAIISGGKGGAEDKIKALESAGVIPVAKRPRDGDEEARVPPAKKKCHEPSRQEPKPLEQPKQKDLAKRPRDGDEEARVPPAKKQRQEPSRQEPKPLEQHKQKDVAKRPRDGDEEARVPPAKKQRQESSRQEPKPLEQPKQKDLAKKQAKDPWRRGPATGTRRPECHRRRRSAMSLPVRNPSPSSSPSRRTWRRGPTLATGTRRPECHRRRSSARSLPVRNPSPSSSPSRRTWRRGLATGTRRPECHRRRSSARSLPVRNPSPSSSTSRRTWRKGPSLATGTRRPECHRRRSSARSLPVRNPSPSSSPAEGLGEEAGQGPVAKRPRDGDEEARVPPAKKKCHEPSRQEPKPLEQHKQKDVAKRPLPRDGDEEARVPPAKKQRQESSRQEPKPLEQPKQKDLAKKQAKDPWRRGPATGTRRPECPGEEAAPGAFPSGTQAPRAAKQKDVAKRPRDGDEEARVPPAKKQRQEPSRQEPKPLEQHKQKDVAKRPRDGDEEARVPPAKKQRQESSRQEPKPLEQHKQKDVAKRPLPRDGTRRPECHRRRSSARSLPPVAKRPRDGDEEARVPPAKKKCHEPSPRGEEAPRRGRGGQSATGEEAAPGAFPSGTQAPRAAQAEGHSEAGQGVPLAKPVAKRPLPRDGDEEARVPPAKKQCQEPSRQEPKPLEQPKQKDVAKRPLPFNGDEEARVPPAKKQCQEPSRQEPKPLEQPKQKDVAKRPQRGRGGQSATGEEAVPGAFPSGTQALEQPKQKDVAKRPLPFNGTRRPECHRRRSSARSLPPKQKDVAKRPLPFNGDEEARVPPAKKQCQEPSRQEPKPLEQHKQKDVAKRPLPRDGDEEARVPPAKKQCQEPSRQEPKPLEHPKAVAKRPLPCDGVEEARVPPTRPAEKQRWTPSAEELEALKRLLRGSSVPILSAKKAMAMLGPNPHLLGAGKDGEAYLNRKANLVKVPGVQRLVAVCLESAMIVTRYAGPTMSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEN2</accession>
    <name>A0A3R7PEN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hemocyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_018729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tyrosinase family. Hemocyanin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003446">
        <property type="protein sequence ID" value="ROT63385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEN2"/>
    <dbReference type="SMR" id="A0A3R7PEN2"/>
    <dbReference type="STRING" id="6689.A0A3R7PEN2"/>
    <dbReference type="Allergome" id="12159">
        <property type="allergen name" value="Lit v HC"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005204">
        <property type="entry name" value="Hemocyanin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF5">
        <property type="entry name" value="FAT-BODY PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03722">
        <property type="entry name" value="Hemocyanin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00209">
        <property type="entry name" value="HEMOCYANIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00210">
        <property type="entry name" value="HEMOCYANIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018618130" evidence="2">
        <location>
            <begin position="20"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="3">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT63385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="555" mass="64230" checksum="D57F80772F1E58D8" modified="2019-04-10" version="1">MRVFVVLALVAAAAVQSDAGGMSDAQKQHDVNFLLHKIYGEIRDSNLKAKADSFDPEADLSHYSDGGAAVQKLMRDLKDDRLLEQKHWFSLFNPRQRQEALMLFDVFIHCKDWDTFVSNAAYFRQRMNEGEFVYALYVAVIHSPLAEHVVLPPLYEVTPHLFTNSEVIEAAYRAKQTQTPGKFQSSFTGTKKNPEQRVAYFGEDIGMNTHHVTWHMEFPFWWQDSYSHHLDRKGENFFWVHHQLTVRFDAERLSNYLDPVDELHWDKTIVQGFAPHTTYKYGGQFPSRPDNVNFEDVDGVARIRDLLIIESRIRDAIAHGYIVDKAGNHIDIMNERGIDVLGDVIESSLYSPNVQYYGALHNTAHIVLGRQSDPHGKYALPPGVLEHFETATRDPSFFRLHKYMDNIFKEHKDSLPPYTTEELTFAGVSVDNLAIEGELETYFEDFEYNLINAVDDTEQIADVDISTYVPRLNHKDFDFKIDVSNNRGEEVLATVRIFAWPHFDNNGIKFTFDEGRWNAIELDKFWVKKYRSDTSETIELDDKPLQLRVNENNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEY6</accession>
    <name>A0A3R7PEY6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative voltage-dependent P/Q-type calcium channel subunit alpha-1A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003357">
        <property type="protein sequence ID" value="ROT63915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEY6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="471"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="662" mass="71899" checksum="B2C89C94D54B5782" modified="2019-04-10" version="1">MRCQETSGHPPPCPVPTLASPEILLYCTFKVWDSTSFQRPLQDDAGDAGDILGYMRAIHVLYDAPSPSPLRPKQGRGPIQDLTFKRKLKLAEESPRRTNASGHKQSFQSKAPSTLFPSKPLPRSSRLPRSSRPSPFHASRPSPFPRSFPSKPLPRSSRPKPLPRSSRPSPFHAFPPLPRSSRPSPFHALPVQAPSTLFPSKPLPRSSRPSPFHALSSSPFHALSRPNALPVQALPRSSRQAPSTLFPSKPLPRSSRPSPSTLFPSKPLPRSSVQTPSTLFPSKPLPRSFPSNPFHALPVQAPSTLFPSKPLPRFFPSKPLPRSFPSKPLPRSSRPSPFHALPVQAPSTLFPSNPSTLFPVQAPSTSSRPSPFTLFPSKPFHAVQAPSTLFPSKPLPRSSRPSPFHALPVQSPSTLFPSKPLPRSSRPSPFHALSVQAPSTLFPSKPLPRSSRQALPVQALPRSSVQAPSTLFPSKPLPRSSKPLPRSSRSPSTLFPSSTLFPSKPLPRSSLQAPSTLFPSKPLSTLFPSKPFHALPVQAPSTLFPSKPLPVPLPRSSRPSPFHALPSSVQAPSTLFPALPVQAPRSSRPSPFHALPSKPFHALPSKPFHALPVQAPSTLFPSSPFHNATLPVPRPFHALPVQAPSTLFPSKPLPRSSLRTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFH9</accession>
    <name>A0A3R7PFH9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_013872</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000273">
        <property type="protein sequence ID" value="ROT85449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFH9"/>
    <dbReference type="OrthoDB" id="6344823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="133" mass="15383" checksum="01ED8A3F2C8E8CA2" modified="2019-04-10" version="1">MHVNTHTGARPFTCDVCGKGFMRRTTLNAHRTIHDASQFSCPTCNRPFKRSSERLIHILLKVCLRKQRILRRTTSGWFCDVCNEGVPQPEEHRCPVKGRRRQCPVCGMDFGGQRDHKMLTHVRQDHPEFLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHQ4</accession>
    <name>A0A3R7PHQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative tubulin beta-2 chain-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_015065</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002879">
        <property type="protein sequence ID" value="ROT66873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHQ4"/>
    <dbReference type="STRING" id="6689.A0A3R7PHQ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000013">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="12">
        <location>
            <begin position="276"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT66873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="56335" checksum="883070584A9C0796" modified="2019-04-10" version="1">MLLSPLSPSPPSRHHLHSPSFLHPFPHASSLPPPPILHPIPSSSNPCFLSIPSLLATISHSFLPNFPPHDPPPSSTPIPSPQYLPSPCFLSPFIPLFLPPPSSTPIPSSPIIFLPHASLSHPSRHHPPHFLPNFFLPHASFSLHLSPSRHHPHPIPSSQLSSSPCFLSPISPPPPATILHPHSSSQYLPTPCFLSPIPLSLPSLPRPLLPATILHPHSFLPNFFLPHASSLPSSPALPLQVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYEICFRTLKLATPTYGDLNHLVSLTMSGVTTCLRYLTVAAVFRGRMSMREVDEQMLNVQNKNTAFFVEWIPNNVKTAVCDIPPRGLKMAGTFIGNTTAIQELFRRISDQFSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLLCERRRKCGRIEADARASVNINRPSTLLTTSPPRRRRKGRAPFDSGRRAGKRELRRKVFCVRIPEPAPITSSVRRRCRRCSLPSFALIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIM9</accession>
    <name>A0A3R7PIM9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sialin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_008439</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIM9"/>
    <dbReference type="STRING" id="6689.A0A3R7PIM9"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17318">
        <property type="entry name" value="MFS_SLC17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000003">
        <property type="entry name" value="Solute carrier family 17 member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF399">
        <property type="entry name" value="FI19708P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="433"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="58"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT73123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="566" mass="59864" checksum="A02AE3E68725187A" modified="2019-04-10" version="1">MASAGSSVLSIQYADEDPSAGDGGLQSKDPDGSGSQTSGSSSKAFAGEARECWAARYTFALMAFLGLAVEYSLRVNLSIAIVAMAGTSEVSATSNASQDVCPLTNNGTDSGGKQTEGEFDWDEQTQGLVLGAFYYGYTLTNLVGGRASEHFGGRLVFGLGAATSSFISLLSPLCARTSTGLFIASRVLMGLSQSRGLKGRIPNALSRPSYSYVASEGHSAPGEQVFAVCTANCAGVTMPALNSLMATWYPPEERAKFGPLIYGGMQFGTIVCLPVSGWLSASGFLGGWPSVFYVFGALGLLWGVPWFLLVHNRPESHPGISAAELEFIAGHRNTVKKSEIVAIPWRAIITSGPVWACVVMAWGGCFGFYALLTELPTYLANIQHFDMSNSGVLSALPYVCLWVIALLWGALMDRLYASGHLSVRRIRRLSTAFASYTPAVALVVMCFVNCNSTLAIVVLCVAVGCTGTSYSGSILTEQDIAPNLAGTLVGITNTVGSVTGFIAPAAVGAITKGNQGSLSAWRTVFVVAIATYVVTTTLYLFLMSSDVQAWNEPREVKKEVKEETRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ72</accession>
    <name>A0A3R7PJ72_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013619</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002702">
        <property type="protein sequence ID" value="ROT68250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ72"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="370" mass="41547" checksum="71D0550665713D65" modified="2019-04-10" version="1" fragment="single">HSYLNPPPVPATEDSPTSTRISPCRFSLSPSLLPSLHVTSIPSSHSLTPFLRFIIIIFFHLLRLISFPHFFLHLLRLTSLPLTSLLTSSSSFLHIPFPSLLLHHLLLHLLLSHLLPYLIPPHFIPSSLRFTCSFPHFRLTSFSLLRSFHSPHFILFISFASQVLLFSQPPLFFHLPLFHLPSSFSSFPSSFSPLLPISNILPICLSLPPLLLLFPPLVLQPLFLIRFLPYQSFSFLNPPSLLNLSFFSFCSIPSLLFLPYLFSTTPVSFSSPYSFLPFFPSLFPFLFLPLSCFSSSLLFSPSLILLPSFPHLISPHPSFRFLPYLPPTLHILSSSSSPPPPPSPPSPSPPPFPLSSIPPPPFYYPSTPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJP8</accession>
    <name>A0A3R7PJP8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_007444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001942">
        <property type="protein sequence ID" value="ROT74066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJP8"/>
    <dbReference type="STRING" id="6689.A0A3R7PJP8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT74066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="957" mass="103342" checksum="97D5BD785C18DA9E" modified="2019-04-10" version="1">MLTARDLASVQRLLTHIVPTIPWPLSSNLLKTFIKLSTTRMNSPEVSQDRSDSPRLMASSHCAPWLPHAVPHGFLTLCLMASSRCASWLPHTVPHGFSHCALASSHCASTLCSWLPHTVPHGFHTVPHGFLTVHSSHCASWLPHAVPHGFLTLCLMASSHCGSWLPAVPHGFLTVPMASHTSLLTVLMASSHCASWLPHTVPHAVPHGFSHFSHCAHGFLTLCSWLPHTVPHGFLTLCLGFSCASWLPHTVPHGFLTLCLMASSHCGLLTLCLMASSLCLMASSHCASWLPHGLMASSTVPHGFLTLCLMASSRCASWLPHLCLPHTVPHLPHTVLHGFLTLCLMAFSHCASCFLTLCSWLPHTVPHGFLTLSSWASSHSYGFLTCASWLPHTVPHGFLTLCLMASSHCASCGFLTLCLWLPHTVPHGLMALTLPHMCLMASSTVPWLPHTVPHGFLTLWPHGFPHTVPRWLPHTVPHGSSHCAHGFLTCLWLPHGAHGFSHCASWLSHCAHLCLMLLCTSHCASWLPHTVPHGFLTVPHGSSHCAHGFLTCAHGFSHCASWLPHLCLIFTVPSWLLTLVPHGSSTLCLMGFSLLCLMASSRCASWLPHTVPHGFLTLCLTVAHGFLTLCLIGFSHCALASFTCASWLPHTVPHGFLTLCLIASSHCASWLPHAVPHGFLTLCFMASSTVLMASSHCASGFLTLCLMASSHCASWLPHTVPHGFLTVHAVPHDASSPHGFLTCLTAGLTSLMASSHCASWLPHTVLPHVPHGFTHCASWLPHAVPHGFLTLCWPHVPHFTLCLMASSHCASWLPQLLTLCPHGLPHAVLMLPPHCASWLPHTVPHGFSTVLMASSLCLMASSHCAHGTLCLGSLCLTLTLCSWLPHAVASWLPHTVPHGFLTLWPHGFLTHCASWLPPLAHSSHTVPASAGFLTQPQLPHAPHGFLTLASCFSHCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKX9</accession>
    <name>A0A3R7PKX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trypsin 5G1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006277</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001803">
        <property type="protein sequence ID" value="ROT75193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKX9"/>
    <dbReference type="STRING" id="6689.A0A3R7PKX9"/>
    <dbReference type="OrthoDB" id="9977936at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000002">
        <property type="entry name" value="Transmembrane protease serine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF83">
        <property type="entry name" value="COMPLEMENT FACTOR I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="167" mass="17790" checksum="91F0FE30E0496363" modified="2019-04-10" version="1">MHDRSHRHEAGLVRRGIVEVVPHPQYGDVILDHDIALIKLSKPVVFNQVHIAPVCLPSPGQKFDEGTAVVTGWGSMAYFCSKKYFPYVTENMICAGLKEGGKDACQGDSGGPMVIDNGVGGYVLAGLVSWGIECAMPDHPGVYTNVANYAAWISEVIAGSETCDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN43</accession>
    <name>A0A3R7PN43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009849</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002241">
        <property type="protein sequence ID" value="ROT71821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PN43"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="138" mass="13847" checksum="A25C59AEC4D221BC" modified="2019-04-10" version="1">MNLHEITPETPDRPAAPWSYVYTDKAAICVIDSDALKPPSVSNMKVSVLISLALTLALASAAPAPAPVGMMDPASNPFIPSFVKNFIPSASEIAALAALHTTPAPPPLPTAAKPAAPAVPAAAATVAAIIPVAPVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRL3</accession>
    <name>A0A3R7PRL3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc knuckle</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRL3"/>
    <dbReference type="STRING" id="6689.A0A3R7PRL3"/>
    <dbReference type="OrthoDB" id="6356350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="18008" checksum="FF1A3E2952617FBE" modified="2019-04-10" version="1">MIWEFQEAFNLKEEPLGRTNLVEHKIETGDSDRVYVPPRFIPYALRPAVEAEVQALKEQGHIRVSSSEWNAPIVLVKRKDKSHPRLCVDYRALNSQTKLEFYPLPLIEDILYQVSQSKWFSTLDLRSGTIKYHWMTTQYRSQPSPPMKDISSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRZ0</accession>
    <name>A0A3R7PRZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001083">
        <property type="protein sequence ID" value="ROT80713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRZ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="669" mass="71455" checksum="26A95CF40C2DC110" modified="2019-04-10" version="1">MLFNPSLLIRRVASHESTPGAGSLPSLIRRWTTCRQDSPVDALSSPRLLNLNIGSINEINCRRRDLPPGACAPPYSFCDVAVAKGRYSPALSSLPLPSSGNRGYTSSARLDSPRRLRFSFFPSPSGGVSAQGDSPPLASLPSPSGVSPGGLPGAGSIPSPSGVSPGDSPARWLSSLSFGVCRQGTPALALLPLLRACRQGTPRALCSPPSLLRACRQGTPRRWLSSLSFGTSVPEAWSPRGIPGAGSLSLSFGACIAQGTLSFGVAALLPLLRRVARGLPALALPSPSGRVARDSPALALFPLLRACRQGDSPALALFPLLRACRQGTPRRWLSSLSFRRVARGLPGAGSLPSPSGVSPGDSPALALFPLLQACRQGTPGAGFSSLSFRRVARGFPVGFRFQGRRWELGKPRRRASWMRGLGLRRVYRMTGARWLSPFTSSSLPPLTTPTIRPPLPLPPTPHHYPSMPPITLYSPPSLLSIAPIPPLHCIPSPPPSPPIPIHTHTPNHPILPPFPPLLYRPQFLLSIASLPPPTHHYPSIPHHHPHTPPFPPSLSPPIPNLHCFPSPLPTLPIHPTITPTTPPFPSSQSPPIPPLHCFPHHPPHHPLPPPLYRPQFLLSILPPPTTPTPPPPPSPPSPPHPTPPPPSHRFESSVHAIRFPHRISIVHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUS4</accession>
    <name>A0A3R7PUS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear hormone receptor family member nhr-48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003702</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001500">
        <property type="protein sequence ID" value="ROT77646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUS4"/>
    <dbReference type="OrthoDB" id="6347502at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.565.10">
        <property type="entry name" value="Retinoid X Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035500">
        <property type="entry name" value="NHR-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48508">
        <property type="entry name" value="Nuclear receptor ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="530"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="215"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="598" mass="67300" checksum="56E002816D8234A0" modified="2019-04-10" version="1">MLAWLEGYCDSTHGQESSANYPRTVSMVSPAILHSNENLPRRANPVLLGGHAFKRVQRKSESEGHTTAAGPHVDETIVRHTKAYGVDRYPDQSRLGQLHIYPFNHAANQCHYSNQSSDMIGLSSPAHLLNNTNPMILTQQVHNYYGYGNSPTINGCSVEGFYYSDLSSAYGKCHIIPGKPKGQIPPAYCESKVKGECHEPVRPYPLWKPFRPSKNPASPSPTNQDSQSISHVSRRKGSTISREDQNVMDLVGAMKASFRQDRRRGPVYDRPLKILTDKELKTVLKPNDYDELMGLIKLNLSTLTSNLHQHVGMDTIEGLGKLYSLFVERRTHFFTKIPFFKHLCLSDKPRLLRLAVAISTHISAAQHIDTSTYTWPRNDTSHASSCLPILSASTLRQIVTHEHFLTIMKFYTNYCHIYADPNVSLMTEVLSLFYDEPGLSDPRSASSARSHYLALLSRYLIAVHGWQRGSDILKVIIRSQREARQLTEIHQYVEFRAQSPRQSLTDVTNSLAENFVKMRVSVQDTISKHIAQQQQEQRPPSPTLCAQDPQPSERQGNEAAVFSSLLSRLATCDDPEVLAAAKHLLPTSLLLRFLHLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWF7</accession>
    <name>A0A3R7PWF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_002032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001268">
        <property type="protein sequence ID" value="ROT79250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWF7"/>
    <dbReference type="OrthoDB" id="6369869at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="367" mass="39464" checksum="829FF317CF9A6146" modified="2019-04-10" version="1">MEKKSRVSQGRGRGGARSDDSEFWSYVCHVAGQLHSRPHDGRTMRVTLSHFALLLAVAGHAAGAGYGCKPQIHYETFFKTIYNEVPVLKTVASQHLVPKVFTEVIYDTVYRARTLYQTSTQYITTTEYLTRVIHDRETKTVADYVYLPDVQTTVKNLVQEQVAVITTTLYTTEYTPARLYSTRFATYTTTVTHPVTLTHKSQVLVPRREHVTSTFAKHYPVTVTYTVPAPPPSGYGAGGGYEDNLVIQTNAVVKIKPSYVTTYVQKTLYLTNTNVERIPVYVTKTVGCGGGGGGHDLAAYGSSSQALHVAVGGEAGGALGGGGAGAGGVVPLSGQLVGEDFLPGSGAGQIHLQPGFSAAAEDSYAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXA0</accession>
    <name>A0A3R7PXA0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL18</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L18</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_019783</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003705">
        <property type="protein sequence ID" value="ROT62369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXA0"/>
    <dbReference type="STRING" id="6689.A0A3R7PXA0"/>
    <dbReference type="OrthoDB" id="6353017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="210" mass="23629" checksum="0FC7636295DD071F" modified="2019-04-10" version="1">MGKDISHRFDRKVRRRAPKSEDVYLRLLVKLYRFLARRTNSKFNKIIMKRLFMPRVHRPPLPCPRYLSWPTSPPAAGKIITVVGTVTDDNRFYEVPKMTAGGEVITFDVLARRSPLGKNTVLIQGRRKAREAYKMFGRAPGLPGSHTKPLVRSKGASSSVPVEEGPAVVTRNSFLINSYNLKLCFPCSMCISNQDCSTLVTRLGCTTLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZ88</accession>
    <name>A0A3R7PZ88_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003299">
        <property type="protein sequence ID" value="ROT64203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZ88"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="489" mass="55504" checksum="05442D85439288BE" modified="2019-04-10" version="1">MCHPNRQRRYDRLSQSGTLSDSETLLLSTTLTYSLRHSLTLFIRHSDTLTLNHSHILPQPLILSATLILFSHSDALLSHTSLTLLLSATLTYSLRHSLTLFTRRPDTFTLNHSHIHSQPLSHSSSDTQTLLLSTTLTYSLSHSYSQTLSHTLRHSDTFTLRHSLKDTHTLSQPTQTLLLSDTLRHRDTFTLNHSHILSQPLRRFYSHILSLTLLLSATLTYSLRHSLTLSIRHRHLLSTLSIPLRHFYSQPLSHTPSTTLSHSSSATQTLLLSTTLTYSLSHSATFTLNHFKRHTLFIRHSDTLTLNPLTYSLSHSHTLHQPLSHFHSQPLSHTPSATLSHSSSATQTLLLSTTLTYSLSHSATFTLRHFKRHSHTLSETQTLLLSGTLTYSLSHSLTLFTRHPDTFTLNHSHTLPQPLSHFYSQTLFKRHSHTLSQPLSHFYSQPLSHTPSATQPLPQMKRRDPLDVTRRGWKSPLESPGHQWASDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q0N4</accession>
    <name>A0A3R7Q0N4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-(1,6)-fucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_023892</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000759">
        <property type="protein sequence ID" value="ROT82907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q0N4"/>
    <dbReference type="OrthoDB" id="2014825at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046921">
        <property type="term" value="F:alpha-(1-&gt;6)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045573">
        <property type="entry name" value="Fut8_N_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027350">
        <property type="entry name" value="GT23_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19745">
        <property type="entry name" value="FUT8_N_cat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51659">
        <property type="entry name" value="GT23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GT23" evidence="7">
        <location>
            <begin position="1"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="260"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT82907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="40162" checksum="87C59B89B09F3833" modified="2019-04-10" version="1">MRQLQGERIGSQLHHLSYCFLASYGTQRTLILDTKNYNGNPEGLETFFLPLSDTCTSYNKSQMVAWPGKKDSLVVRFPSMDRPNPRPNYFPKSIPKDISERLVRLHGDPFAWWMGQFFNLQIRRSDKLIREAVYIDLSVYMQEVDEFYKQLELRQPVAQRRIFLATDDPKVIPEINKKYPEYKVVYNSASVDSTRLNQRKKASSLRYFLADVYFLSRSDFLVCGMTSNICRLCYELMQSLHADASTRVSSVDRDYYFHFEVDHVAKARFPHKPRRPEELEMQEGDLVEGSNRGHFSEHPSKNNGFLWGKNTRTNKSGYYPAYKTVEVLKKADVLSFEHIDRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2F1</accession>
    <name>A0A3R7Q2F1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015198</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002892">
        <property type="protein sequence ID" value="ROT66746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2F1"/>
    <dbReference type="OrthoDB" id="6365107at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="20398" checksum="02A60E2B498D146F" modified="2019-04-10" version="1">MKKEELLLEDSGDADDYKYDPRYPYDYGNRSDYGSRHSSLRSKNRVVFVEPDEESVSSQFWESNPWLEDLIALVKERGPTVLVVLMLGGLGIFCTLAGWWLLAVAGALNYLGGIIVQGVVLPVVGLILLMMSMMVFRTNWSSFKKEPEGVSEVFDADPTILNKAIVRPSCLVNSEFRRQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAP7</accession>
    <name>A0A3R7QAP7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">JHE-like carboxylesterase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_008548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002078">
        <property type="protein sequence ID" value="ROT73043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAP7"/>
    <dbReference type="OrthoDB" id="6370620at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43142:SF1">
        <property type="entry name" value="CARBOXYLIC ESTER HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="5">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT73043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="221" mass="26106" checksum="0F4FA90A82DD8CE8" modified="2019-04-10" version="1">MAYNLDKASADDLVQNFSVSGPLSLTFEGWEEDPEYLARRAFHHYLGPIELTEEKRDPIIRLYSDRLFDMCHMDAVGQHLRTSQKQVFTYKLQHRGEHQYVSTYFPSVPDWVKNYVTHADDLQYLFNQEEYNMTLQRDEDLFVSRIMVELWTNFAAKGHPTPDLSLGFKWAPTLSSSNSYLAITSSPFMKTFQECRIHKFWKNMPTKTNQRLYPDRFEPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBB4</accession>
    <name>A0A3R7QBB4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative flocculation protein FLO11-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008068</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002024">
        <property type="protein sequence ID" value="ROT73496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBB4"/>
    <dbReference type="OrthoDB" id="6430068at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031866">
        <property type="entry name" value="DUF4758"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39072">
        <property type="entry name" value="RE48511P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39072:SF3">
        <property type="entry name" value="RE48511P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15950">
        <property type="entry name" value="DUF4758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018523379" evidence="2">
        <location>
            <begin position="21"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4758" evidence="3">
        <location>
            <begin position="349"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="872"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="960" mass="105075" checksum="1A5F8CC1B34D0DE0" modified="2019-04-10" version="1">MERAMLLNLLLLALVASATAQLAPVYNPGGTPEPVVVEATPTAEAPTEKPAAAAEYVTKTVYGFLDFTTTVGSTVMIFTPQSQSAKPKPSKTRDPVLPSRLNRPSSRITLRPTPTPTPTIPKVTATPAPSVLPSKLPAISSSSTLQSSFFEDHTALDIETLFDVSPDEEIAIDYDAEYPEYEEPVFEEVIEEVKEEARKPTAAPTRPKPFRRFKSSSSQEQGNRRRLDLNYFNSRKKTPSLRRQTGGSTIVPITIEGTGTFAPKSTSVIRPTVVPTTPSEVVVSATQGFATLSVIGPFSTAINNELGQVKEHYDFLSSAPVLDVEETYDVYDVEPTASLEDLYSSGLVTSDSSFPTGLVTKLGGTIVSDGLITVHETSVIGTYIAGQYAQILQSTSHIFQTTPVPEISLNSPSLPEDYETVKSVIKGSATQFLSPESTASLPLESLFSEPSSRERNSRKDEEGGSAIQVRLREALAKRLGSSQSQNTRQDRSRLAQDPYVDEEKDEFDLKLSGSDLRPSFGFRGSTPVTRTPRVSTLYAEEVKPTTYRPRFKPTSTRRFGSSRPTSVRSPPNAPFRQTRPANRWRLNTSPRPKVNINRRPVNQPDTYDDLQAADESQSISRPTAPEPIIPEGGEETLRIVTSTPADGATDVWFEVATIRSLHTFRVGTTKNTRYVTFTKTTTHSIDPTPAPLGPQDDLYETPLFENILDDGPRDVSTLPPVDLGESDVTALLETVTETFSTTELMKKTSILPVLHAGETSFYTLTQTYHITRVVTALKTMPPYEAFSFIPENSLNEFNGQLLAEGTENDESLLPGEIEYDENGEIVDTTSGTRVPPPPGFPFQDPNLAELAGGQFNPDVFEKQLHPQLTAALQHRQQMQQKQGRGRSQRASRASEASEGDGGVVPALFPPTSLTPSAGTLHLTSTNPLTVWRSVSRRGRLSSGLHSDFRQRGNKRRGRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QEV5</accession>
    <name>A0A3R7QEV5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001643">
        <property type="protein sequence ID" value="ROT76568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QEV5"/>
    <dbReference type="STRING" id="6689.A0A3R7QEV5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="617"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="692"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="714"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="743"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="829" mass="88776" checksum="E01AC704327D9F07" modified="2019-04-10" version="1">MVLSVISSIFTSSLFILFHFLSFSSVLLLPPFPFLFPLLELPLPLPRHEIPPLSFLPPPHSHFSLRSTSSFSHAFSTISSLFFVHHHHSLLHHHHPLLHHHHASTPLPPHSTTLPTTTIPSSSNHTPSHHHHTLSHHHHPLHHTTTLSLHHHTPPPHHHPSSTTTIPPLHHHPLLHPPPSLPIHHHRSHTTIPPLHHTPSSTTTTPSSPPPPPPPPPPSLPPPPPGPPPPPPSPGPFLLHHHPLLQPRTNASSTTHHPIHHHHQPPPPQPPPPPPPPPPPPPPATTPPATTTTLLPPPPPPVLHHHHPSLHHHHLHLLHHHHFPPTPQPPSLHPPPHPLLHTPRSSSTTTADPLSSTSTTSPGRPSYTATLRAPSLLHPPQPLRVGLSTTPPASCHHQPPPPPHHLPPSSPRTDPSSHHTDPPPPPPPTPSSTPPPPPATTTTPSSTTTTTTTPLLHHHLPPPATTTPSSSTTTPSSTTTTPPPPPPTPRSHTPTPPPLHTHPPPPPPPPPSHPPPPLLHHQPPSPPPPPPPPPPPHHPLPLQHHHPPPSPPPTPPPPTTTPSSSPPPPIQPPEPPPLLHHPPPPHTTPLLPPTTTPSSTTTTPSSHPKHTTTHPSHTPPPPPPSTTPLPPPTNHHPPPPPPPPPLPINHHPSKSPHHPPPSSTTTTPLISSTTHPLLHHHHPLLPPPPTPSSTTTTPSSTTTLLHHHHPSPPTTILSTTTTPSSTTTTTPSSTNQQPSSPNTTPPPPPHPHPTTTTPSFHRHHPLRPPPLNSIHAEYSHSNPTPRSVLLSPCTTQGPQSYLGRSRDNAAQTTDGDVIRLKDLLLLSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGA7</accession>
    <name>A0A3R7QGA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer dense fiber protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002928">
        <property type="protein sequence ID" value="ROT66480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGA7"/>
    <dbReference type="OrthoDB" id="406368at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="81" mass="8234" checksum="6EA744437617B01A" modified="2019-04-10" version="1">MGGQTNGTWTPTKRRGPIAAEFSSPGPAAIALKSGIGSGGATKSRPPAFTMASRHEPKNEKVGPGPGQYNVTGLSNKGQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJW4</accession>
    <name>A0A3R7QJW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000081</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01001007">
        <property type="protein sequence ID" value="ROT81165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJW4"/>
    <dbReference type="STRING" id="6689.A0A3R7QJW4"/>
    <dbReference type="OrthoDB" id="428480at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016231">
        <property type="term" value="F:beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000063">
        <property type="entry name" value="Beta-hexosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF26">
        <property type="entry name" value="BETA-N-ACETYLHEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="10">
        <location>
            <begin position="125"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="9">
        <location>
            <begin position="338"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="181"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="215"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT81165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="760" mass="87117" checksum="83EF1ED5073EE3C8" modified="2019-04-10" version="1">MAAKQPPSTRARPAFSPLPIGASSPEAARERPESRAPGRKAVRVALLSYLQKLWIFSPFSSMVEMKVFVAAALLALAAAEGYFRLPNPYSYSCQDGLCVKEERIVSGEYNSLDKCQITCGEYGSIWPQPTGKVELSKETVSFSPLHMRVTKAATSDNRVARMLDNAIQHFTRTIHFLHPDFPQTEKQPLTPEDFENTGHFNQKFQNEDPAQQEQYRQRSEYDRNQLRQRPRYSREEPESFIRRSPFLRKRSNPGVESHNVNIEITVTASDHKLRLDTDESYNLVIQTVGDETTATILASTYYGARHALETLSQLIAYDDINNAVQVVRDAQIQDAPSFRYRGFMLDTGRNFYPKEDLMKLLDSMAYNKMNYFHWHINDAASFPMYSNRVPKMTYYGAYDARKVYYPEDIREIVEYANLRGISVIPEIGGPAHNAAGWQWAQKEGKGKLALCTDSNEPWFELSKEPPSGQINPINPEVYPILGELYRDLMDYFDPEMVHMGGDDVSFKCWQSSEEIQQYLSQTKRESTSREYFELWNTYQSSAYNKLQEAAQGRQVTPIIYSSSFARNYIDKDSYVFQISEFANESVIADYIKNGYKVIFSNQDQWNLGCLTNTWVGDKAENCPSEVPTWENFYRNSPLDMLEYLGVNNARSDIQQADGTNTKNLVLGGEATLWSFDTDANGLQSKIWPRMSAFAERLWTDPQSSLSGTSFTQKRLNIQRQRMVYRGIAADPLQPEFCLQDEGACFSREQYRARTTLNNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKS2</accession>
    <name>A0A3R7QKS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002412">
        <property type="protein sequence ID" value="ROT70562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKS2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="54730" checksum="C6B003ACB6FE53C0" modified="2019-04-10" version="1">MFHKTLQISRENLDAASRSTSPKETFEMQRREKYLPAGDKALQKKSGILQIKFSKYRVTPPTHPSPPLLHIPTPTVPPFHPPPFLHIPTTNSPSLPPPPPSQTHYQQSLPSTPPPSHIHYQQSLPSTPPLLHKPTTNSPSFHPPSFTYPLPTVPPFPPPPSHTYHSPSLPPPPPSHTHYHSPSFPPSSHTTTNSPSLPPPLLSHIHYQQSLLPPPPPSHIHYQQSSFHPPSFTPITTSLPPPLTYPTQQSLPSPPPSHPTTNSPPFHPPPSHTHYQQSLPSPPPPPLHTTTNSPPFPPPLLHISTTNSPPFHPPPLHISHYQQSLPSTPLLHIPQPNSPSLPPPLPSFNTHYQHPSLPPPPPHTPLPPYQHPTTSLPPPPPSHTHYQQSPPFHPPSFTHPLPTVPPFLHPPLPSHTTTISPSLPPPPLLSHYPLPTVPPFHPTLLHNTRLPPFHPPSFNIPTTKTNHSIPQSDQSIAPIPGQTDRPGPLTSLEDGVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QQ30</accession>
    <name>A0A3R7QQ30_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative latrophilin-3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_007157</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001909">
        <property type="protein sequence ID" value="ROT74345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QQ30"/>
    <dbReference type="STRING" id="6689.A0A3R7QQ30"/>
    <dbReference type="OrthoDB" id="1100386at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011:SF347">
        <property type="entry name" value="FI21270P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="112" mass="12591" checksum="56D6119B92C2D9CB" modified="2019-04-10" version="1">MCVGYLAPFSYVSLTLAFTHAEGYATRKACWLSPYGVLWTFAGPLAIIMLINAVAYFMTMQVAWRENALIANKTYIMAGIFTFLNSMQGIVIFVFHIAINTPITQEVKRILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRM7</accession>
    <name>A0A3R7QRM7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001746">
        <property type="protein sequence ID" value="ROT75686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRM7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="40819" checksum="C075F36D93ED6064" modified="2019-04-10" version="1">MLLPPPLLTPPPSTPRTLPSAPLTPTTSPPCPQLSHLTRRPPLVSPPDLPLLPHPLTLLPPPLPLPYLPSIQSAFSQTSTSTSPHHSTPPTPISNRHPIPTPYPTTILLLCHPPPPSIRCLLFPHHLHLLPPPPHPLLPYPQPPPSLVPPQHSASSQTVHAHLLPHLRSFLPHHPLLLHTSYPHHPLLSYPPPLHHPPTTSRPPSISPPQPETSHPSHLLPHLPPPPPLQPPSIVLLDGRTVLSARTSHLPSYPTPPPPLHSVKLRSLLSQTSPPPSYPTRPPPPPHLPSISPLSQTSRSDPYPYPTPSPSTPPCQLVLLSQTFPSSTSLPHQPLLPPTALPFLPPPPSYPHHTSPLLPSIISSSRTSTPPSAPPLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QUN1</accession>
    <name>A0A3R7QUN1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative transcription factor SOX-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001315">
        <property type="protein sequence ID" value="ROT78905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QUN1"/>
    <dbReference type="STRING" id="6689.A0A3R7QUN1"/>
    <dbReference type="OrthoDB" id="6377549at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021934">
        <property type="entry name" value="Sox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050917">
        <property type="entry name" value="SOX_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45803:SF5">
        <property type="entry name" value="SOX100B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51516">
        <property type="entry name" value="SOX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Sox C-terminal" evidence="9">
        <location>
            <begin position="182"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="298"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT78905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="39777" checksum="AC3EAA49C21C5D87" modified="2019-04-10" version="1">MFLPPPTGKKWRSLTPTERRPYVEEAERLRLKHMADHPDYKYRPRRRKQQQPKKPGGSSTPGAAAASTPSSTSSTPTITSSPAVEAQLRKVASPSVPGGFLQATLTAPLSNSNNASSNTSIPSLPPTTFTPPTTFTPPVLPALHTPDTSPTPHQASRLLHYFSQSQQNYSGYMYPGAAPGYPPHNYDYHDYMNGAEGYYPAHYDPQGYTHDHHHPAFSHPAFSSPRSDGVAVPPHGEAEVFDDVDRSEFDRYLKGPERVSAVATTFTYTPPANTRYLQVGGGQYQDSQFTALIKEEPEDYSNGAGAGGGGSGGGGGGGGGVPSAAGGPSTGITSEATKSTEAACHSPDAAKPDTNTSSLLSALADVRELYYEHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVE7</accession>
    <name>A0A3R7QVE7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001638</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001211">
        <property type="protein sequence ID" value="ROT79644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVE7"/>
    <dbReference type="STRING" id="6689.A0A3R7QVE7"/>
    <dbReference type="OrthoDB" id="2019940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF54">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT79644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22909" checksum="C9F1A45AA8D33515" modified="2019-04-10" version="1" fragment="single">REELRRKIQTYTKFLVVRHPLERLLSAFRNKLEGNGRPARVFKRVYGAKIIREYRRGPESSRENTTSVEDLEKESAKTTGEDVRFSEFVSFLLDKEDLAIVNEHWRPYESLCHPCALSYDVIAKYESLEEDSEGFLRLIGAPEGLHFPQYAPTNTSALLHSYLASVKPDRLAQLMMAYQRDFQLFQYDGVSIPKGAML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QXE3</accession>
    <name>A0A3R7QXE3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclease HARBI1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_025068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000920">
        <property type="protein sequence ID" value="ROT81772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QXE3"/>
    <dbReference type="OrthoDB" id="6358932at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="23754" checksum="69313457A757CEAE" modified="2019-04-10" version="1">MPLDREYESFFALILSEELDSVDNAREILQRQEIYKSSANQQRNHVEVDFKDVLPIVIKTGEPVSKKRKKGGRSQEDYLQKGGMLAFYDLNDFRSHFGMTRSQVEDLLTDLQPHYHYERGSKLPLENVVLASLWVLASQESYRHLAQCSVAIKACCILHNMCLENTDTEPVNIEEEDLPFPPRRPCSDYQINLAGEAKRNAIAASFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QY31</accession>
    <name>A0A3R7QY31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000781">
        <property type="protein sequence ID" value="ROT82722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QY31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="904"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115624" checksum="D12B66514F929EF2" modified="2019-04-10" version="1">MLQASDGKPKKPLELEKGDWSCFRERRKPKKPWEWKGRLGSCFRRAKEAKEASGSWKGRLGHASGERRKPKKPLGVGKGDWVMLQASEGSQRSSGSWKGRLGHASGEEGSKEAWELEETGHASGERRKPKKPLGVGGETGSCFRRAKEAKEAWELERETGSCFRRAKEAKKPWELERETGSCFRRAKEAKEAWELERETGSCFRRAKEAKEAWELERETGSCFRRAKEAKEAPGSWKGDWVMLQASEGSQRSLGVGKGDWVMLQASEGSQRSLWELERETGSCFRRAKEAKEAWELERETGSCFRRAKEAKEAWELERETGSCFRRAKEAKEAWELEGRLGHASGERRKPKKPLGVGKGDWVMLQASEGSQEALGVGRETGSCFRRAKEAKEALGVGKGDWVMLQASEGSQRRGVGRETGSCFRRAKESQRSPWSWKGRLGSCFRRAKEAKEASGSWKGRLGHASGEKEAKEVGKGDWSCFRRAKEAKEALGVGKGDWVMLQASEGSQRSLGVGRETGSCFRRAKEAKEAGSWKGRLGHASGERRKPRSLWKRETCFRRVGVGRETGSCFRRAKEAKEASGSWKGRLGHASGERRKPKKPLGVERETGSCFRRAKEAKEAWELERETGSCFRRAKEAKEAPGSWKGRLGHASGERRKPKKPLGVGKGDWVMLQASEGSQRSPGSWKGRLGHASGERRKPKKPLGVGKGDWVMLQASEGSQRSPWELERETGSCFRRAKEAKEALELEGETGSCFRRAKEAKEALGVGKGDWVMLQASEGSQRSLWELERRLLQASEGSQRSPWELERETGSCFRRAKEAKKPLGVGKGDWVMLQASEGSQRSLGVGKGDWVMLQASEGSQRSLWELERETGSCFRRAKEAKEALGVGRETGSCFRRAKEAKEASGSWKGRLGHASGERRKPKKPGELERETGSCFRRAKEAKEASGSWKGDWVMLQASEGSQRSPSDIAISANFEFLQSRLLASVISHSEKRASGTRTSFCSVVKRGLTNGLAAFTWRLETCPEHVRRRVLRNAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SGW5</accession>
    <name>A0A3R7SGW5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extensin-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004589">
        <property type="protein sequence ID" value="ROT60742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SGW5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018782282" description="Extensin-like" evidence="2">
        <location>
            <begin position="27"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="568"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="658" mass="71138" checksum="AEF081524CF8DF8F" modified="2019-04-10" version="1">MRDKKGSNTPHILCIIFPSRLSLLLSLSYSPTATPPSSPFSPTNGAPTLLLCPPTSATPNSFTHLSFSQTHTNPTLSPSPPYHTPPLFLLPHQPHSSSLYPHPLPALSPTKPHPLSFSHTNHPLSFSPTTPPLSSFPPPTPPSSSPTNPTLLSILPTATPPSLLLPHKPHLSPSPPTNLTLLLSPCQPHPLSFSSHQTPQNLLSFSPPTQPFSPLHPPEPKPPSLFSPSKPHPHLLLPLQPHPLLLSECPPPTANPRPSPPRKPHPSLHYVPHQTPPSLLSPPTAKTATPATQPLQPNQTTTTDLSRGRSPTDQKPHGPLSFIPALIEDHHPLYLLPPPTPTLSSSPTQPTLSPFSSAHIQQPEPYSHCSPSNQSPTLRARFSPTEPHPLSFRYPNHAGPTPRSLFSSPPNNLNSLSFSPSNPTNSLSLYDPRPSSHFSPTRTPPSPPLAPHQNPSVLSRCGLPLQPQPSLLLPSKRTIRPLPFSPTQPLPPSLPSHPHPTPRSPHTLSVLRPTNPKPSISFCPPPTPPLSFSPSNNPYHALLLSFTPLQPHHPTPLLSCLPAPPTPPPLHLPHHPTLSPLHRHIFLPPPNSPPPSPPSTSLPQHHNPARSVSEKSKAARLTVLARLWQSVLKCKKIGRPRDPDKHGTSAFTVNEEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SL05</accession>
    <name>A0A3R7SL05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SAPK substrate protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016733</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003104">
        <property type="protein sequence ID" value="ROT65310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SL05"/>
    <dbReference type="STRING" id="6689.A0A3R7SL05"/>
    <dbReference type="OrthoDB" id="10254930at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036435">
        <property type="term" value="F:K48-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032435">
        <property type="term" value="P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903094">
        <property type="term" value="P:negative regulation of protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14302">
        <property type="entry name" value="UBA_UBXN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041923">
        <property type="entry name" value="UBA_UBXN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46340:SF1">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBA" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="7">
        <location>
            <begin position="244"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="67"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="226"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="282" mass="31010" checksum="1119CE536C5365BA" modified="2019-04-10" version="1">MSALQTLVEMGFSENSAKKALAVTGGGGVEQAMEWLLAHADDPGINDPPAEDVTGAAAGHSLGSQEGSEKMETSETPESKESGDAPAEKSEETGEASADGEAAKSIKCDDCGKLFKTSEEVEFHAVKSGHSNFSESTEEKKPLSEEEREQKMGQEIAERKRIMQEQEMKRIADERRREKLEDKIARQKIKEQIEADKRARKEMFANKEAPTQPQPPKPQPVAQPAQKKEYTTTSLNRKDGVPTDEPFNLSMSFPRKNFSDEDMDKPLDVLGLVPSAVLMVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SRE6</accession>
    <name>A0A3R7SRE6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002251">
        <property type="protein sequence ID" value="ROT71767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SRE6"/>
    <dbReference type="OrthoDB" id="6362774at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="21717" checksum="82746DCABF0B406D" modified="2019-04-10" version="1">MLDEQYLTLKSCCCYSLREGCIAISISRLIISLLNLPKPCISLSRLVDDSLAQGDSIYNDEFFISITLILIAAANVVGSAILIAGVLKRHRSMMKMWVYFVVVFVVAHVYNMFKDQGPRNGVQFLLSAMDIVFVSYCASVIRCYYLSAEVSVGLQAQPSRCSDNLGADEEMLQNAAEREIAISDPRLWVAALNAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVI2</accession>
    <name>A0A3R7SVI2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative programmed cell death protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_004275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001567">
        <property type="protein sequence ID" value="ROT77113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVI2"/>
    <dbReference type="STRING" id="6689.A0A3R7SVI2"/>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298">
        <property type="entry name" value="PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298:SF4">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="135"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT77113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="368" mass="42238" checksum="AE8D0922C79B266D" modified="2019-04-10" version="1">MSSDPVVELGFLENKTPAWKLRSKFFPSKVGGYPAWLALKDLPNGQQLTCRNCSKPLAFLCQLYAPYHDKEECFHRTVFVFICRDADCSKENNASNIRVFRSQLRRDNEFYPPDPAKDVEPGSESPGAADFNNLCRVCGGCGPKVCGGCKVARYCSKDHQALDWKAGHREECKKPETVSKVSCKGNAKFLFPEYEIDMEPEELDERREKTEEEVMQEYEALLRSGRVTRDLDDDVEKNEDDLIKMATKETDKQFQKFRTRIKEYSDQVIRYDRAGEPLWVSSENKPQDIPPCPGCGEAREFEFQIMPQLLVHLKVDSPGQSIDWGTVVVYSCKNSCSQDKHYIEEVAYKQDYAPISQVMKNHPEVNMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0I1</accession>
    <name>A0A3R7T0I1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_022653</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">P0 forms a pentameric complex by interaction with dimers of P1 and P2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000587">
        <property type="protein sequence ID" value="ROT84158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0I1"/>
    <dbReference type="STRING" id="6689.A0A3R7T0I1"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="9">
        <location>
            <begin position="111"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT84158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="34174" checksum="FC3BC6EB533528A1" modified="2019-04-10" version="1">MVRVDKSTWKANYFTKITQLLDEYSRCFIVGADNVGSKQMQEIRMSLRGCAVVLMGKNTMMRKAIRAHLESNPSLERLLPHIVNNVGFVFTNDDLCEVRDKLLQNKKRAPARPGAIAPCPVTIPAQNTGLGPEKTSFFQALQIPTKIARGTIEIVNDVQLMNEGDKVGASEAALLNMLNISPFTYGLVVQQVYDQGTVFSPKVLDITDEDLLKTFQRGLANVASVSLAIGFPTIASVPHSIVNGFKNLLAIAAATDINFKEAATLKEFLADPSKFAAAAAAAAPAAAAAAAPKEEAKKEEEPEEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9C9</accession>
    <name>A0A423S9C9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Voltage-gated sodium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_021522</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004522">
        <property type="protein sequence ID" value="ROT60840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9C9"/>
    <dbReference type="STRING" id="6689.A0A423S9C9"/>
    <dbReference type="OrthoDB" id="2984333at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001518">
        <property type="term" value="C:voltage-gated sodium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005248">
        <property type="term" value="F:voltage-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0086010">
        <property type="term" value="P:membrane depolarization during action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019228">
        <property type="term" value="P:neuronal action potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.350:FF:000022">
        <property type="entry name" value="Sodium channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043203">
        <property type="entry name" value="VGCC_Ca_Na"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037:SF288">
        <property type="entry name" value="SODIUM CHANNEL PROTEIN PARA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10037">
        <property type="entry name" value="VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="7">
        <location>
            <begin position="38"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="494"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="544"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="494"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="575"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT60840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="650" mass="70849" checksum="148AB0D6DBBF208B" modified="2019-05-08" version="1">MVVISKGKDIFRFSATDAMWILSPFNPVRRTAIFILIHPLFNLFIICTILANCVLMIVPATEKVEASEVLFTAIYTFESGVKVMARGFILEGFTYLRDAWNWLDFIVIALAYVTMGIDLGNLAALRTFRVLRALKTVAIFLLSDSGGHGALLSPPQTRFLKYGLLSPLPGTEPNFLSSYLLFFLSLFPLRLKTIVGAVIESVKNLRDVIILTVFSLSVFALLGLQIYMGFSLTSHFPCLTFPLPHTSLASYFPCLTLPLPHTSLASYFPCLTLPLPHTSLASHFPCLTLPLPHTSLASHFPRLTLPLPHSSLASHFPCLKLPLPHTSLASHFPCLTLPLPHSSLASHFPCLTLPLPHTSLTLHFPCLTLPLPHTPLASHFPCLTLPLPHTSLASHFHCLTLLHTPLASHSLASHPCLILPLPHSSLASHFPASHLPHFPCLTLPFTSLPDTSLAYTSLASHFPCLTLPLPHTALIFSHLPCLLFPSPPTPHPTFYPSPPPSPSLPLPPSPSLPSLPSLPSPTPPPHPPLPRIAAASCMMLDPSLPLHTPLPDPTPFTHTPPLTPHPAHHTRPTPSHTPAPPPSHTRPTPSHRPHPLHTHAPPLGPTPSHTRPTPFTHTHLPLAPLHETNLGALVPLVHFQRVLETGDPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SB41</accession>
    <name>A0A423SB41_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020832</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004196">
        <property type="protein sequence ID" value="ROT61387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SB41"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="45538" checksum="26C1A0F58E14B861" modified="2019-05-08" version="1">MRTERDVRTVWRKGLSERDPSTFARPHVLSLSLQDARSPPHVSLSPSGRPDSPRPHSLPSPSGRPIPRPPLSHSSLGRPISPAHTLSLSLRTPGFPAPHSLPLPQDSGFPRPTLSLSPSGTPDSPAHLSLLSLRTAPIPLPTLSSSPQADARIPPPTLSLFSLRTHRFPCPHSLPLPSGRPIPLPTLSPSALRTADSPAHTSLSPQRKRPAFPPTPLLSLPFSADSPAHTSSLFPQDARFPPPTLSSSSPSGRPNSPATLISLSLRTPILRPHHSLLIPSGRHDSPRPTPLPSLPSGARIRPHSPLSLRRPIPRPHLSLFSLRTGAPDHSAHTLSLSLAGTPDSPAPSLSLSPQDARSPPPTLSLSPSGRPIPRPPLSLSPQGSGPDFPRPHSLSLPQDARFPAHTLSLSPSGRPIRRPHSLSLYSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEZ1</accession>
    <name>A0A423SEZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Spermatogonial stem-cell renewal factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019392</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003558">
        <property type="protein sequence ID" value="ROT62748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEZ1"/>
    <dbReference type="STRING" id="6689.A0A423SEZ1"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="THYMIDINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515:SF0">
        <property type="entry name" value="THYMIDINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="136" mass="14665" checksum="28370F2404300DD2" modified="2019-05-08" version="1">MYAARDVTSTVKSVPLIVSSIVSKKAAETVSGLVLDVKFGGGAFMKTQEEAGALAKKMVDVANGVGMATTALLTTMDVPLGRAIGNALEVREAIECLRGNGPRTSRSSSLTWVESYCWVRKRPLRLRKLARSWPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFF5</accession>
    <name>A0A423SFF5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Collagen alpha-1(IV) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003520">
        <property type="protein sequence ID" value="ROT62950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFF5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="462" mass="50932" checksum="05F5F1AE18C3893D" modified="2019-05-08" version="1" fragment="single">MAIGLMAPICPLAILFVISWPSYLSSWPSLLLLSLAILFVLMPSYFVLLAILFCPHGHPSCPHGHLYLSLNGPSYLSFAILVAHGHPICPQAIFVLKWPCLVCPSWAILLCASWPSYLVLKWPFLFCSHGHPICPHGHHYFVLWGPSYLSVLDLPHGHPISSMAILFPHGHPIGPMAILFVLNGIILLVLMAIPICPCITILLFLIPIPSLSSMPSYFSSWPSYLSSWPFLICPQYGPILFVSWPSYCPHGHPICPSWPSYLSSWPSYLSSWPSYLSSWPSYNVSSSTIVLMASYLVLHGQFGLFLGSLPWPSYICPHGHPICPHGHPLCFLIGLSYICPHGHPFVPQMAILFVLYGHPICPHGHPICPHGILFVLMASYLPPSYVCPHGHPICPHHARLPFLFCPHGHLFIYPDATDTTVPTQKIVRATHALVGTLIYGLSALLDGTVPLAYGLFNGESGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFJ8</accession>
    <name>A0A423SFJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003512">
        <property type="protein sequence ID" value="ROT62979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFJ8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="575" mass="59865" checksum="FD10A686B0D11DF3" modified="2019-05-08" version="1">MLFSLPCPPHYLHFLPLYFFPCVLYFFCLLFCPQALLFFYTSACLAPCPCLPALPFPAPPLPLLPHLFLPPCPPTCPLPLPPQPPLVPTFPTSSPPQPLCPHLPCPPHLPHPALPLCPHLPSLPNFPHLPCPSACPHPSPPSPCTCLPTCPPFPALPPAPPSPALPTCPTFPCHLSPFPALPTSPALYLPLPPHFPALTAPYLPSPPPLPLPPCPPPLSPPSPAHPPAPTFPHPPLSPTPPALPTCPHLPLPSPLSHLPPTSPALPPSPFLPSPPLSPTSPTSPALPPAPTSPALPTCPHPLCPHLPLPSPSVPPSLLPLPASPPVPLSLPSPCPHLPQPSPPAPYFPSPPPLSPPPHLPCPPHLSTFPALPPVPTFPYPPTCPPSPTFPCPPHLSHLPLPSPPPLSPPSLPPLPPPSPAHPLPTFPCPHLPLPSHLSPLPLPPTCPHLPYPPHLPLPSPALPPVPLPLPSPSVPTFPCPPLSPFPAFPCPHLPLPSPPVPAFPYPPTCPHLSLPSPFPLPPLPSPSVPTPPALPTCPPPSPPPCPPSLPPPSLPGGGDVRCAPVLHLLLLPPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJB8</accession>
    <name>A0A423SJB8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017761</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003277">
        <property type="protein sequence ID" value="ROT64300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJB8"/>
    <dbReference type="STRING" id="6689.A0A423SJB8"/>
    <dbReference type="OrthoDB" id="1601181at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10454">
        <property type="entry name" value="GIY-YIG_COG3680_Meta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12934">
        <property type="entry name" value="LEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034998">
        <property type="entry name" value="ANKLE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011015">
        <property type="entry name" value="LEM/LEM-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003887">
        <property type="entry name" value="LEM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46427">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46427:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03020">
        <property type="entry name" value="LEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22945">
        <property type="entry name" value="LEM-3_GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63451">
        <property type="entry name" value="LEM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50954">
        <property type="entry name" value="LEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LEM" evidence="2">
        <location>
            <begin position="420"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1005" mass="112934" checksum="88379AD0200F68FF" modified="2019-05-08" version="1">MEESFSTRYSQFLRDLENYEQHQIDTDEDGWKSTPQEPKLNDSGPSRIHCPDFLKKLKQTIQKYQHDSDSDSDIVSLQRCLEKNLNEASRSFCRASSFASFTSEDSQDLSSEQTLNELDIAQLTIDLTDNLSFLTDDLFEAIYVPPNKSISVLEKSHNLTSGNGICLSQEGCITLNSLGIENDTVLEADCDDTLTDSVIIVAEKNQNNLRGHGDSVAGRKPEKDIKCIDEKLKEYPIITTAPRNTSKPDQCQTVNLVKAPRKEVPYLERCARDKPLLRDPTSKLFDGLTKTLTPKGKISGTNPPTTTFSSPKRVGQLTSVPSTPRSHQGLVGKGAPSTSSSCQSFFSVVEEFLYKDPEAGIALIERRCPSSSSIASTGSQFGSLPRSLIQSRKITEVLQPPQDKANIHFEESLNSIGTVTDSIKALSAETLRARLKAVGYTPGPITAGTHRVYQRHLMRIRKNPQMLEEENADSAKPSYPRELKMALEDPSSVDWISWGSLERVMSSPFCQPDPMRHWRDGTTKSCFNYLLLDPRITQDLPLRGLMMTDAEKFQCFISAIFYIGKGSRGRPYYHLYEAIKSLENGKKKNKKIERIHDIWSEGVGVISLHVFQNTIPVEAWTREAAMITAIGRQEIVELPVLSQEGSEVSCLSEDFPGSQQICFDNEKKKSEDRKLGSNCKKDSTYTKYSVNDLFMEESFSTRYSQFLRDLENYEQHQIDTDEDGWKSTPQEPKLNDSGPSRIHCPDFLKKLKQTIQKYQHDSDSDSDIVSLQRCLEKNLNEASRSFCRASSFASFTSEDSQDLSSEQTLNELDIAQLTIDLTENLSFLTDDLFEATYVPPNKSISVLEKSHNLTSGNGMCLSQEGCITLNSLGIENDTVLEADCDDTLTDSVIIVAEKNQNNLRGHGDSVAGRKPEKDIKCIDEKLKEYPIITTAPRNTSKPDQCQTVNLVKAPRKEVPYLESEHHYRLFLFHETRRSRANPIDTDTDREHVTILTGFLVAVPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJE4</accession>
    <name>A0A423SJE4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_017809</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003283">
        <property type="protein sequence ID" value="ROT64263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJE4"/>
    <dbReference type="STRING" id="6689.A0A423SJE4"/>
    <dbReference type="OrthoDB" id="2281547at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051999">
        <property type="entry name" value="Mediator_complex_subunit_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019680">
        <property type="entry name" value="Mediator_Med1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12881">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12881:SF10">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10744">
        <property type="entry name" value="Med1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med1" evidence="11">
        <location>
            <begin position="189"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="759"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="871"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="871"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="906"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="959"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="989"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1008"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1049"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1083"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT64263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1129" mass="122234" checksum="71414C5358D8E7BD" modified="2019-05-08" version="1">MSPFFHPPQHVPVTNSRHVWAWLGIHSRPPLRVETRSLGRVWKALSIKGPLLGAPCIRRSLPRPASAAQEGGCAVAAPRRSCPKTRPAEGQHLLPRFGLSERVALIDPVPRGMFRDPIPTPATPATATATATNVSSPTSTAWQMEVLMERLRSKAGGYRSLVESAKGIKHAIMNKSHLMDPSERAALGSCLDSLQGNIKVTSLSAMVERLEAIAKQLGLKFTAGTTGSEVFVSCDMFYVEVLLDTDGRVRDVKVELAGDQNAREGQSSPELMECLSSGDFVDFTAHLEGFSSIYQLNADKKIKSKAFQALQALETDLTKLFELAQETLTDPYKLVLKSPVGLLQRRRGGHAMRLVYFVSPYELLDVQAGRSITLTTETPSSRDLSHYVTVNIDASNSHKLQTTTLMIITKQPNGKKLPSFSGLTNDNSMTLPACFSLKLRKPMPVSLALIQRINEVTCLDCVDLSNQQSLISLIVQQATDGQFEYNSNRGLFVTLPDQQHCYFMTSSGELPGVMVSSIPFTHPTHITNILMCLRAQAAFNALISSCVRPASKQDPDSAYMFEVTAASHEYISVTFEHPQEESTATAEIDLTDLCNARCRLHTLTPDPGFCSEEYATKVLQRCLSIPVTMRAVMKKVAKEERKDAVTGGDSAVMMGGGKLNSDLNQNTKFLLNEYDKLGMRRDQLMAPHVNNLNNVVANTAPGHGYYNGPFPSSNHHSGGGDASTNPLAALGNAVQEAGTPLGYGALLGAVGHKPNLNQPFLGDAKPAKVRKKKPGLDLDRKSPKYGDDVVIDLDERSSDSYLGEGVPAIVDNMKRRDVKMEKLQTIFNKRRSSSDSGTTDIATTDLAALREQVYGAANAANFAKINSYSHKDSKDIKKVKKPRTDGPDSRKSPIVLDLTETESSSKKSGSGSGSSSSHSSSSLSAALLKRPGIEIIPIPGSTTPISIPSSITVTPVIKSADDKNKDKKDRRDKKDLDRKDKKRKRDDSPSSNSSSSSSSSSSKPSKVQIISSNLKHSPISSLEKFKSESGSKSGLTGITVKPSTPPYQSPSKKPSLSPGMTKSMIHNKLSVSPTHKPNKVIYSPNQSSSSHSSSPKGRSSPKPSTGSPKHPSMSPKHTSLGKPSMTQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNC6</accession>
    <name>A0A423SNC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium/myo-inositol cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_016362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003060">
        <property type="protein sequence ID" value="ROT65659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNC6"/>
    <dbReference type="STRING" id="6689.A0A423SNC6"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005412">
        <property type="term" value="F:D-glucose:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819:SF150">
        <property type="entry name" value="SODIUM_MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00457">
        <property type="entry name" value="NA_SOLUT_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT65659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="45389" checksum="A6093FC0344DFF11" modified="2019-05-08" version="1">MMVQRAMAAKSLSHAQGGTLFAGYMKILPVFIIVMPGMISRVLFPNEVGCVDPEECLKFCGSATSCSNSAYPKLVLEFLPGGMRGVMVSVMLSALMSNLTSIFNSASTLFTMDLWMLCRPKAKAREQLIVGRLFIVVLVVISILWMPIIERSQGGQLFVYIQVIASYLAPPIAAIYCMAVIWKRLNEPGAFWGLMIGFVVGMVRMSLDFYYTEPPCGEEDLRPNIIKKIHYMYFATLMFWGTCLVSVIVTFITEPPEEWRLIRTTYFTRLDHRDREDDMEMKERVNNELLEVAHTVDEASVDGDHHVPWYKKAYYCICGFDVSKDAEEQAVAMNEHLAELTNLHQETWEKYLLNSMLVVILVAAVALFVYFSISPFTEEEVRDIQRRKLEELGYYDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPL1</accession>
    <name>A0A423SPL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Actin T2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_015899</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPL1"/>
    <dbReference type="STRING" id="6689.A0A423SPL1"/>
    <dbReference type="OrthoDB" id="6330576at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048646">
        <property type="term" value="P:anatomical structure formation involved in morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0558">Oxidation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT66131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="41811" checksum="B617493B20B02739" modified="2019-05-08" version="1">MCDDEDQCALVCDNGSGMVKAGFAGDDAPRAVFPSIVGRARHQGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWYHTFYNELRVAPEESPTLLTEAPLNPKANREKMTQIMFESFSVPAMYVTIQAVLSLYASGRTTGQVCDSGDGVTHMVPVYEGFALPHAILRLDLAGRDLTNYLMKIMTERGYSFTTTAEREIVRDIKEKLCYIALDFEGEMNVAAASSSLDKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGVQETVYSSIMRCDIDIRKDLFANIVMSGGTTMYPGIADRMQKEITALAPSTLKIKIIAPPERKYSVWIGGSILASLSTFQSMWITKDEYDESGPGIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSL1</accession>
    <name>A0A423SSL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002835">
        <property type="protein sequence ID" value="ROT67185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSL1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="44827" checksum="D7B60E1EFA7D2EEE" modified="2019-05-08" version="1">MGEQTSKQAEESQRERERRRRIAGDRERPCVRACMRVLYPLLALLPSLSHSPHRHSLLSFPFLLLSTSPPFPSPSCFTISRLSQRCSTKFGCHVASPPSIRKLLPPPSSLSPLPPSFPPRSTPLLHHALRLSLLSLPFLLSLALFFSVFLSPLWFSLSSSPSFPQASLSFPPLLYLSFSLPSVLTPAMLFPPLPFLYYPLFSPFSPSSCSLSLLLLRSPFFLLSSLLLPSHPGLSPLSHPPLPPFPFPPPHPSVLSELNSTVFLFRSSRSSLSSFTSYPPPPSLPSSPPLPPSSPLSSSRDPSPTLSSHLFLLLRSILFFLHFFVSSSSSPPSLRPFFFSPSSPAPFFFLFSLLPLFPPSSFSSPSSHLFSFPLLHLFSPPPPPLLIFCRGRCILQEVHAGKSFCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSW4</accession>
    <name>A0A423SSW4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002824">
        <property type="protein sequence ID" value="ROT67283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSW4"/>
    <dbReference type="STRING" id="6689.A0A423SSW4"/>
    <dbReference type="OrthoDB" id="6378431at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052258">
        <property type="entry name" value="Diverse_Func_Domain-Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37612">
        <property type="entry name" value="FIBROIN HEAVY CHAIN FIB-H LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37612:SF6">
        <property type="entry name" value="GLYCINE-RICH CELL WALL STRUCTURAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019411045" evidence="2">
        <location>
            <begin position="17"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="577" mass="60599" checksum="B468B579E6EBB9A2" modified="2019-05-08" version="1">MWRLTATLLLLALTSAEPQGGYLPPPPTKPPPQPCIHPDSNLCRVQIVTTPRYYHNLHDHSNSILQICQPSHSHITTTSVVYDAQIQTSVDVQIVNQANTQYITTTVVSQQIIPTTFIRTRYFTNTQFQTSIVQQTTTVFDNRVATQTIPGQAVQQTRFVTSTRVVPQVSYVTQTRTETQVVPVEVTRTQVQTINRPFTEFLTQTTYETRLVTIPGRDVVRTRVQTRLLTSVIRQQQQGNTRYVTSTRVQQEVQTRFVPGQNVVSTTVVRREQVVPYTDVTTRFSNVVVTREQVVTRTNYATQTRVQTQVVPQEVVRTQVVPTTIFTTRFETRFQPFTQVQTVTSTNFRTGPAVVQTREQTQTSVVQAPGQDRVITSEVVQTSVRQEVTFQTVGSPQQVTVTRTVTASCGQAGGGVGGAGEVLWWVSGGGASGGFGGSMEVDLADQVWIWQVEVDLAGSGGGSSGGGFGGSSGGGFGGSSGGGFGGSSGGGFGGSSGGGFGGSSGGGFGGSSGGGSGFGGSSGSGFGGVGGSGFGGVGGSGFGGVGGTGFGGQTGGGSFGGQGGYNYNSPRNPLSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SU21</accession>
    <name>A0A423SU21_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Putative splicing factor U2af 38 kDa subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_014196</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the splicing factor SR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002771">
        <property type="protein sequence ID" value="ROT67716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SU21"/>
    <dbReference type="STRING" id="6689.A0A423SU21"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12538">
        <property type="entry name" value="RRM_U2AF35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000055">
        <property type="entry name" value="Splicing factor U2AF 35 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="14">
        <location>
            <begin position="42"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="183"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="208"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT67716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="239" mass="28442" checksum="A0B187576C4599B3" modified="2019-05-08" version="1">MKPVFDEDKKSILIFYLYVFYYALRRPFSYGHTSLTACSTLQTVLILNLYCNPQNSAKSADGSHSTVSDEEMQEHYDNFFEEVFVECEDRYGEIEEMNVCDNLGDHLVGNVYIKFKYEEDAEKAVVDLNNRWFGGRAIHAELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRELYGRKRRRSHSRSRRRHRSRSRSRERRRESKDRSSVLDRFSAHSQDKDQREGRFGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUJ3</accession>
    <name>A0A423SUJ3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014002</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01002740">
        <property type="protein sequence ID" value="ROT67885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUJ3"/>
    <dbReference type="STRING" id="6689.A0A423SUJ3"/>
    <dbReference type="OrthoDB" id="1022360at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000768">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF21">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="26"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="265" mass="29742" checksum="D673FA1CACA78547" modified="2019-05-08" version="1">MSNEEVMEKLREICSPIKAESVYEKDCEIGEIGSGASGTVFVAKEKATGRKVAVKDIDLEKQPKKELILTEIQVMKELQHENLVNFLDVFLQENHLWVVMELLDGGPLTDVVTETVMKETQIAAVCYHTLQGINYLHKNGVIHRDIKSDNVLLGKDGSVKVTDFGFCANISGDEKRQTMVGTPYWMAPEVVNRKQYGKKVDIWSLGIMAIEMIDGEPPYLNETPLRALYLIASTGKPIVASWDKLSPEFQITYPGSDVFNSVWEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVJ7</accession>
    <name>A0A423SVJ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Broad-complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_013601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002699">
        <property type="protein sequence ID" value="ROT68266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVJ7"/>
    <dbReference type="OrthoDB" id="10261408at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048513">
        <property type="term" value="P:animal organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048666">
        <property type="term" value="P:neuron development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF109">
        <property type="entry name" value="FI07618P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="31"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="442"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="116"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="183"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="268"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="460"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="275"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT68266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="58497" checksum="01785D63B8789344" modified="2019-05-08" version="1">MGADQFLLTWNNHRSNFAEVFTQLRVQDQLVDVTLLCDGGSYPAHRLVLAACSPYFHQLFTRLPTQHPLIYLRDVKQAELEALLEFIYRGEVSVANSELTGLIKIAESLRIKGLGDVSQRDQQPQAGEKRAGTPFSPASPVSQNNNPRPKKVPRLSNNNGESKGLEPNFASLLSPANSYGHALNKSSNNKSSDGFAQLMDSGCPDLPEQELDSDQTPNPAWDPSLSESKLRSCLEGLESVTAAQSLAQSVAHTVAQSIAIPRTLFTSTPTKVSSSKKESTDNAKEGSRGSSRRKNHEPQESKRGKGGLINAMLNVNADTEKEGKQVAKENVKTEPDTDNITDTDTCPEPSPLPLYDTTTDIAGSIGDLTNPIFASYRHMLSLGNDDRSFSPLIPTTVQEQQQVPSPTGRESRSLTCQLCGATIKHIANFRRHMKQHLNPRRFPCPWCSAAFGRKDNLKTHTRKHHPAEVEAQEAGVLRAESARTDSGEGGEDGTVLTGLNGLESEGGDGTAPDDGDKEDVDREDSSDHHESLVEKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXN8</accession>
    <name>A0A423SXN8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT69005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXN8"/>
    <dbReference type="OrthoDB" id="7474049at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF4">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="434"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="577" mass="64077" checksum="4A083B07389DE567" modified="2019-05-08" version="1">MAKIKIKVLGGPSPRKRDLLANALYGAEIRVLRYIAIQDGYLALIDDDIQAEKLFSKDVVLSLEKLGFSPVLPVDMKAKLTLVFKKLDRQDEITAAFPEAQVDNIFVMKANHIIKVRFTDHATAKAIKEKGMYLFKLYVAPWQIEFERPIRAVAQKAAQETVQATTNAWKPLINQVRQDIKQKTPDPTIHLALPDNLSKEILVVLLHAHLQNLIAPEKGLLLNPSPRDLNLHRFRPPPAPEASTFTGSGTTTSAPETSDCTGSGTGAQPAQMSEPQPAEAQTAAPQSSPQESSPTSAPPTTGPSVRPKYIHIPSEAETRDILSDTPLDTPGPPPPTPDQTEPGHSHVDDEGMERLMDGTATDPTYYGIRLFAENQKNEYSDRYEIGQEIINKRIKWLLTKEEHAIVVTIKKLHQHLKDDLLAVEVNTPQGPIILATLYIPPRRQYIPEPDILQLLRHNKPIYIMGDFNAHHTLFGYNDTNAVGRGLASYIQQGRLTHLGPHTPTYIAHNAATTPDIVLANHIAHLHYHITTDDVTSSDHLPVIITLSTNPIMTQHNPENPSNMQTGRDLNKHSKTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY72</accession>
    <name>A0A423SY72_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_012639</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY72"/>
    <dbReference type="STRING" id="6689.A0A423SY72"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="9 11" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="68"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="271" mass="30782" checksum="E026AFB9F6E294E7" modified="2019-05-08" version="1">MSSWNNPVQDTVLPSTNPYGNYTVVDTVPENMLHMVHAHWYQFPPMNPLWYGLLGFWMTVMGTLSVAGNFVVIWVFMNTKSLRTPANLLVVNLAISDFFMMLTMTPPLLVNAYWGTWILGAFFCEVYAFLGSFFGCVSIWSMVFITADRYNVIVKGVSAEPLTSGGAMMRIAGTWAFTLAWCLPPFFGWNRYVPEGNMLACGTDYLTETELSRSYLYVYSVWVYLFPLAYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEESPEDLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0K6</accession>
    <name>A0A423T0K6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002485">
        <property type="protein sequence ID" value="ROT69995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0K6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="493" mass="53762" checksum="09D0E8498554A993" modified="2019-05-08" version="1">MPRASIYFGRGLPNSISESRDTITGQRHCAFVPPPASLHIPTPSLPLFHLPSNPLTLPPSLPPLLPQPFNLPYPPPSNPSNIHLTLPPLLLPQPFSLSAPPFLTLPPSLSPPQPFHPLPFAPPPQPFPLPPPHPFLHPAPLSLSPCPLPPPFPLPLPSLSLSLPLLSPPPLSPCPLPTLSLTPLSPLPPQPFPPPPLPPQPFPSPPSAFSPLPTPHPFPSASPPPCPPAFPVLLTSPAPSIPASHLIDTNALLSPLPFHRSSPSHLFFSLSWSSFLTYLPHFLSFVLLPFLAFLLTLSSSFSLICPSPFPVLLPHFLSSFHLPFLFFFLTLFSSFSLICPSLSCSSSLPYLPFLLSSFHLPFLVFLLTLSSSFFSSFFSFPDLPPLPCLSHFLSFFLSLTWSSSSPYLPHFLSSFPLPFLVFLVTLSPSFSLISHLSFSLSCSSSSPYSLSFPLLFPSPFPGLLPYPIFLIFSLPLPLLPPQFPFPRSREVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T490</accession>
    <name>A0A423T490_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002310">
        <property type="protein sequence ID" value="ROT71320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T490"/>
    <dbReference type="OrthoDB" id="6350022at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019011981" evidence="2">
        <location>
            <begin position="17"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="563" mass="61771" checksum="BC3E1D4837D2A6C1" modified="2019-05-08" version="1">MLSTIFFLALLVGGDSHRLPHNVKDAPGAMIEDLGKVYPITSHVEARFSLMPLRNASLLMIYHRTQLLSLRGNITLDSSLDAHDRRLFNRILSSTIADLDSFVGPLKSSGNIAHGLFGVVDDDTLASELRKYKESLSSVAHSFDSSAHVVNMLAYNVRDLVSAFNNVRGKTLFPLGQRTRFYASLKSFLTVSGLSVIIPVRPPTVFRAYRVHPFPHKTNNSHYMVSVPHTFILREIEGHALSFPTSDLLNSCTKPAKDIYVCFSAPIPSALQSPSCARALISNRLVTSLCSFEEVKDQISPFMLSLSQSFVADVAADPIAIRPSLLTLPTINITIPELHLRDVSKVQDADRLGRATRKHIGCIGRTNKPAVRPPNALPRTRSLCNGKPSALTESSVVCGSHEAETGRPAVRRDQVEDRLPPGDFGRIRRGRTHPGEGRDGGRSPRGPTRTDQAKTRTYAMNPRRQPIRVAAGEAVGTSGQLLGAIFSASRTRRGRWQSDGVTNKAYRIRTPAVGTGCLHRQAVLNIQLLCPARVRLQGRQGSQDQTDLRATYHNSLSLLPSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9K8</accession>
    <name>A0A423T9K8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Broad-complex protein isoform 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_008457</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002062">
        <property type="protein sequence ID" value="ROT73141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9K8"/>
    <dbReference type="STRING" id="6689.A0A423T9K8"/>
    <dbReference type="OrthoDB" id="6374097at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000395">
        <property type="entry name" value="zinc finger protein 513"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001450">
        <property type="entry name" value="zinc finger protein 774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051967">
        <property type="entry name" value="Krueppel_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45925">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT73141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="17127" checksum="F749B7F8C16E633C" modified="2019-05-08" version="1">MKSTGDWDHVRPAALIPVVEIRQPVAASTPTSIAQLMTGACPKTAAIPMGPASGAFTPYTASTSPRGSTPDLAQVAPADKQSFMCPVCGKQFGQPYNLRRHLTTHTGERPYRCPHCNYAASQNVHLEKHIRRIHLNNGQNEHPTGPAVTWPLQATAVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TAM8</accession>
    <name>A0A423TAM8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002023">
        <property type="protein sequence ID" value="ROT73506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TAM8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="419" mass="44828" checksum="52950666CD3D2BEB" modified="2019-05-08" version="1">MRTLVTQASYPPLPPLPFFSHSLLLPLSSPFLSPPLLPSPSEPPFLSSPLSLSLSLLPPLLPSLLSSPPLSLSLFLPPLLPSLLSSSSLSPSPLLPLSFEPPPLFSLSSLPFFLSPSNFSLRLLLSLSLLPSSFLLPSLLSSPPLSLSLSPLLPFSSYFPLLFSSLSSPLTFFLSPSNFLPFVSSSLSPSSLLPFSLQPSLPLLLSLSSLPFFLSPSNFSPLPLLLPPFIHLSSSLSSLSPLPPSSLPSLFPISTFITYFPPPPLSFPMAALTHVSLPTPFLSLFAHPSSHAHPQASSMSFTTTPLSHHTRPSSFTTLPSSSLIHPPTSHAPPPHSTLTRHPRPTPHAHRPTDPPPPSHAHHPTPSHPHTPPHAHTTPTPPTLTRPPLLHPMPPPSPRPPHAHPHTPTPRPSHAPPDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCY0</accession>
    <name>A0A423TCY0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative ribosome biogenesis protein BOP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_007155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001909">
        <property type="protein sequence ID" value="ROT74343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCY0"/>
    <dbReference type="STRING" id="6689.A0A423TCY0"/>
    <dbReference type="OrthoDB" id="5571054at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="9">
        <location>
            <begin position="101"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="541"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT74343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="566" mass="65475" checksum="92710A76AFA5323C" modified="2019-05-08" version="1">MSGKKRKLPTVKDEVFEDEIGNDDFMTKQFDDEGNSDSEYSISEGEEETEIPEDDSEDESDDEPDDKSAERGKSKQVNQKATGSKGAPKSKKAGNIPMNWYDEYPHMGYDLDGNPIIKPDKGDKLDQFLRMLEDPDHERAAYVARRAELIKKGMVTYKTKQKKKRFYDLWGTKGDDQIRRLTQRLETPKMPLPGHEDSYRAPLEYIKEYNARRFTSVRKIPQFYNFVKDRYERCLDLYLAPRKLIKKPLYKADDLLPRMPKPKDLRPFPTREALRFVGHQSVVRTISIHPLGKFLASGSDDHTVKIWEISTGRCLRTFNFQGIIKWVAWNPSPKLFLLAVVVGNKVFCLNPETYLTDRVVVRQTNAVFRVEPDKGDDQIGKQFERVRTAVTWRKPDATEWSNGIRVVLEHFKDVKQPLEITDPFTAIKARIEVAEFHPKLPFLYVVTQTHVRVYNLQKQTMLKNIRANSRWVSSISVHPGVPKEAVRKVAFHRKYPLFASASDDGRIIVSHGMVYNDWITDPLIVPVKELAGHWFLKNLCVLDIAWHPYEPFVLSSGADTTIRLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TD22</accession>
    <name>A0A423TD22_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative puff-specific protein Bx42-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001915">
        <property type="protein sequence ID" value="ROT74277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TD22"/>
    <dbReference type="STRING" id="6689.A0A423TD22"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="3">
        <location>
            <begin position="157"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="493"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT74277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="519" mass="58667" checksum="4650AE81AC16C5BD" modified="2019-05-08" version="1">MVSLSDILPPVSAPVWDRESEDRRRRHQQQQQQQQALVTASRAAPPYGHRKGWIPRSQEDFGDGGAFPECHLDDKGKVKYDVIARQGHSKDKIVYSKLTDLLPSAITSEDDPELQRPSMEEIEENTEKTRQALEKLTQGKISSAMPVRCAEKQAPAQYIRYTPSQQGVSFNSGATQRVIRMVEQPKDPMEPPKINKKVPRGPPSPPAPVMHSPTRKVTVKEQQEWRIPPCVSNWKNAKGYTIPLDKRLAADGRGLQSVHINEKFAKLAEALYIADRKAREQVEMRAQIEKKLQAKEQVRKEENLKELAKKAREENAGLRPAAAGPVDEAEREREKLRQDRSRDRKRESAIANSAADKRGKLTSRERDVTEQIALGLPQKTASGGEAQFDQRLFNQQSGMDSGFGDDESYNVYDRQWRGKSNLGSSLYRPTRTAENEYGADLETLMSTNRFVADRGFSGRTPRNRTGPVEFQRSGAGDEKEEDDLFGVIGLLTEAKKASKRNADGEDRGRDDRDKRRKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDU4</accession>
    <name>A0A423TDU4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">guanylate cyclase</fullName>
            <ecNumber evidence="2">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_006815</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001863">
        <property type="protein sequence ID" value="ROT74664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDU4"/>
    <dbReference type="STRING" id="6689.A0A423TDU4"/>
    <dbReference type="OrthoDB" id="6127067at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008074">
        <property type="term" value="C:guanylate cyclase complex, soluble"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019934">
        <property type="term" value="P:cGMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070482">
        <property type="term" value="P:response to oxygen levels"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000005">
        <property type="entry name" value="Guanylate cyclase soluble subunit beta-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.260">
        <property type="entry name" value="Haem NO binding associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011645">
        <property type="entry name" value="HNOB_dom_associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042463">
        <property type="entry name" value="HNOB_dom_associated_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45655:SF2">
        <property type="entry name" value="GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45655">
        <property type="entry name" value="GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07701">
        <property type="entry name" value="HNOBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="10">
        <location>
            <begin position="158"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT74664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="354" mass="40205" checksum="E25D8A3BB397646C" modified="2019-05-08" version="1">MGLTFDNILSHINTIYVLRTREALITTRGDNRDLGSDQGCLRLKGQMIYLPETELMLYVCSPSVLNLDDLYRKGLYLSDIPLHDATRDLVLLSEKFEAEYNLTTNLEILTDKLQHTYRELESERQKTDKLLYSVLPISIANELRHKRPVLPRRYEVVTLLFSGIVGFSDYCSRHTDIAGASKIVKMLNDLYTAFDCLTDEKKNPNVYKVETVGDKYMAVSGLPETCDHHARCICNLALDMMDKAEGVIVDGQKVRITIGIHSGEAVTGVIGQRMPRYCLFGNTVNITSRTETTGEKGRINVSEVAYKYLQEPQNYDAKFVFTYRGPVPMKGRKEPMQVWFLNRRRPGADAGAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TEJ9</accession>
    <name>A0A423TEJ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative organic cation transporter protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006639</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001840">
        <property type="protein sequence ID" value="ROT74882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TEJ9"/>
    <dbReference type="OrthoDB" id="6484641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="240" mass="26488" checksum="BC8F2A48136C21AB" modified="2019-05-08" version="1">MVRPHQDARAHTARGWFRRHDTHFASPPLPHTPSHPRPLTQQNPRLRTITLSLYTNYLLVGAVYFGLSLSGGDLSSDPFLYMVLTGVVELPAYTLVIPLVARYGRRAPVVAFFFLTAAALLVLPFVPAGSMVLALIGKMSIASAFQVLDLYSSELFPTEVRTRGMSTAHVMSRVGSFSPYIIDYLAKWPLVPVGAVSSVRAASARGTGLALPETLHVALPDTIEHLEEREIRTRRLAWLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF67</accession>
    <name>A0A423TF67_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001819">
        <property type="protein sequence ID" value="ROT75017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF67"/>
    <dbReference type="STRING" id="6689.A0A423TF67"/>
    <dbReference type="OrthoDB" id="6371742at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="45059" checksum="DA3E1F492F072270" modified="2019-05-08" version="1">MSVMAESVSSQGSSWLQVRDGEDGSEDMKDLEDRPTDQEVASMLQSCSSALTSCTSCSQSTQQLSETMHRKMEDIVVRLTSQIESLKSQLEARQPETSSRDRDTTSGSEQQLESHQLEEEDQQQNDEAEQQAETDQVEKPEETQSVEQEEESSEQEQQLQNSQRSSVERQSGCSVEQQVLYSNSFLPAPRTAPVFLPEPEMQIACLPPQDTLGGNLRPSAPSPTPSMYSLRAQAQGVVNSPPRTSLVVPQPTLAPHDATGSNLPPPLLPETTPTARQAAVMSQFSSQQLASGLGHESDDDDFHSTSDNDEGTSLSASHENNGKLIECPMCTLSFQSGAIRLLEEHINSHLEHVCPVCSVAFQRNNQKKFEEHVHAHFEGEDNLEDSNPLDDPTGPWGPQFRATRLLEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG52</accession>
    <name>A0A423TG52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001773">
        <property type="protein sequence ID" value="ROT75463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TG52"/>
    <dbReference type="STRING" id="6689.A0A423TG52"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018788">
        <property type="entry name" value="Proteasome_assmbl_chp_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053720">
        <property type="entry name" value="Psm_Assembly_Chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001044">
        <property type="entry name" value="XPG/Rad2_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10178">
        <property type="entry name" value="PAC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00066">
        <property type="entry name" value="XRODRMPGMNTG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="47126" checksum="F685C843DED7847A" modified="2019-05-08" version="1">MGVKGLWKLIESSGTPVPLETLEHKILGVDVSIWLHQAVRGFRGPGGAAVANAHLLTVFHRICKLLFYRIRPVFIFDGGVPHLKKQTLAARRLKRDVAASKAKQVRDRLLSNLLKSQAVRKALGKTGRGPSDVHVPKPQKKEKDMFELPPLPPPEENEEGMTTIKSEENEDEHEVLNSYDLPNLHHFDYESKEFKALPIETQQVILSELQCTRKENSWAAINEMPQDGKGFAEFQIDRLMKRRKFQVTLDNTQEEIRKKRAVEMEAEMFGELEKHFTMASLIDNTVSTPRPLVANNQQRPASIASKVFASLINGVHTDFAIIVYRNRVFITVTQCGKIGNLYSIHRDTAQKNGFLGLSALAVYDIKCILGVESEEGNQAVRSLAGKLEVPRPLLLSLTLPVLDFPTISAVGEALLKNKCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGN6</accession>
    <name>A0A423TGN6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">guanylate cyclase</fullName>
            <ecNumber evidence="1">4.6.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_005846</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001752">
        <property type="protein sequence ID" value="ROT75619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGN6"/>
    <dbReference type="STRING" id="6689.A0A423TGN6"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011645">
        <property type="entry name" value="HNOB_dom_associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013587">
        <property type="entry name" value="Nitrate/nitrite_sensing"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07701">
        <property type="entry name" value="HNOBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08376">
        <property type="entry name" value="NIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Nitrate/nitrite sensing protein" evidence="6">
        <location>
            <begin position="44"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Haem NO binding associated" evidence="5">
        <location>
            <begin position="358"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT75619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="538" mass="61624" checksum="72A4F4E6D814DEBF" modified="2019-05-08" version="1">MLLLPFVPIMALIIQNSINMVSILEYQNDMQETIDQISTGLGNVTEALQSERAEIAFYLFTNGSIIRRNLSEHFAYTNSLIENLIWPSFRIDDQLFQNKILFRIRLDDFRDKITKFDTPNIEAGIAFYNRANYIFLDQLTREIKEKDASGVWRPLLAYKNMIRAIEHLGISMVFGEQYFGRGDLDQSSYIAFVTNDALGQDFLNASQNFAFWIGTRYQALQKDYPWYSNITRRRLEILGREKIQPDFEKATEYFYAMLGYLDALQKVQYEIRFVLAEGDFLFRAWHSFNAAEAESPLAPPATLLQRRVSLSGRKTIEQTIVREVQASNSHVVIGIALLAVVLIISPVIIILVRMITRTLQAFSETLLHKTHELRFEKKRSDKLLYQMLPSSVAHSLRIPQNGGCRDLLGHHHLLQRHLTLPHSFASQVISLMNGLVTLPHSLCFAGHLPHERLVTLPHSFASQVISLMNGLVTLPHPFCFAGHLPHERLVTLPHSLLRRSSPHERLVTLLIPLLRQVISLMNGLVTFLIPLLRRSSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TME8</accession>
    <name>A0A423TME8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001503">
        <property type="protein sequence ID" value="ROT77612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1360"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1575"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1699"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1767"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1844"/>
            <end position="1874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1948"/>
            <end position="1977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="758"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="783"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1229"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1582"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1702"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1731"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1775"/>
            <end position="1785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1792"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1852"/>
            <end position="1867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1960"/>
            <end position="1976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2041" mass="212209" checksum="621030E4A9178206" modified="2019-05-08" version="1">MEKGVSATRLDATADEASAPLADSIRLVESVGAPTATLVQPWAPPPAPRPNPWAPPPAPRPNPWRQTASPLVESVGGQTGQPLVRIPWAANRQATSALYYPVRVVLHPFFNSSLRFCHYPSASVIVALPIFLLLLCVLPRSSLCSFRSPAYFRVAPTRKLSSFSSRIPGRHPFLSDLAHALPSFVRILFGRPPATLLLRALVLTISTVSLYLSLLSVPLSTPLPSHSLSPPPPFFIPTSPPHSLSLAPHLSRLPLSASLSLTFPLALSFFLSLRPLTPPSSNSPSPPRVVGAIGGVLGPPALKRPDPPPPLSLLSLSPFFPLSLPPSHSLSAPPPPPSTSPSLSPLHPPSPSPPLRPSHSPPPPPHHVSLPPPGSSGYRRWSLGPALNAPLPLPLPHVNSLPPPSYSPSHSLLPQGRRGYRRCPLAALHAPSASPSPLTTPPSSPSHSPLSLPLLILSPPQGRRGYRRCPWARLLKRPLSLSPAPSLSSLSFSASLTRLLFLPPSSFSLSFSASLALSLSLPSKFSTLLILSPATPGLVGAIGGASGPIGGVPGPALIPLTSPCLSPPPSHSLSIPPGSVRAIGRCPWGPGISIAPISLSPRPSPLIPSHSLLTLVTFPSHSPPPTGSSGLPRRCRLGLRLCNALPLAPSPLPPPPLPLLTPPCSTPHSHIFPQGSSGAIEVSLAGLFFSQTPLPLPRPHFSISLGPSGAIGVVGRGYRRCPLAPALSARLTPLLSPPSHSPLPPPGSFGAIGGCAGPGSHAPSPSLPSPSSLARVPPPLPSPSLSHLPSPFSHPPRSSGSIEGVPGPGSQRLLPPLPSPLFSLSHSLLPSRPAPFSPVSLPPLNSLPLTPFLSISFSASLPPPSPLILTLILLSLPPGRRAYPEVSLGPALNAPSPSPRPLSSPLYSPCFPPPLSFSLPSPVSLPPFHSPPPPGSRRGYRKVSWARFNAPSPFSLSPSLSPFLSLSLPSLSNSSSPPSLPLPRPHFPVPHVSPLTLLPLIETLPFFSLSLSFASPSLPLHSLSPPPFQCRSLSSLSHSLLSLFSSSTFFPRPSLSHSRPRSFSSPSRLSLPPPLTPLLSLSPTRVVGAIGGVPGPGSQAPPDPPLVSRSLSPLSFLSSPPSLSFLSRPSPSPLSFSTAPIPPPPPPSNSPSSFSPPTPPGRGLSGRCPGAGSQRLFHRAPPSCSSHLSLSPFFPSPSLPLILLCSPPTLFIPQLSFPSHSPLSPPSPLSFSTPPSPSSFLSFTPSTPGLGVSEVVPGPGDSTPPSPPLSLSLCPPPLHSSSPSLILPSPRPHPPPLTPPLILSPALPRVGRGLSEVSLGPALQRPPPPLSSRLFSSLHFFASPPSLSFSLPLPSPPPPLTPPLTTLSFSSPPPGSRRGLSEGVLGPALNAPSRLSPLSAFSLSIRSLLSLPSPSPPCLTPPAHSSSPPRVVGAIGGVPWPALNAPSPLSPRPSSFSLSFSCLRSTPLFSPLSFSRLILSLPSSLLSPLPRLILHLSISPTRVVRGYRRCPLGPASQRTPTPPTSLLSLSLNLLLPSSLPPSHSPLPSLFIPQLFLSSHSLPPLPFPSPLPFPLSPPPPSSHSPLTSSPPGSSGLSEVSPGPALNAPSPLSLSPSPPPSLSPLPLSLSLSFSASSPSLTPLSFLSLPPGSVGSIEVSLGTLSRPSPSSASLLSPLSRSPLLPSPSPLFLCFPPRSPSSLSPSLPPLTSPSHLSPPPQGRRGYRSVPGPGSQRPPPPLPLPSIPSPSPPSPLLPLFLCFPPPLPPSLSPLTPPSHSPSFILSSLSPRGRRGYRGVPGPGSQRPLSSPLPLSFSLFILLLPSASLSPPSHSPPLTPSLHSLSLSHSLLPPPSNSPSHSLSLPPGSSGLSEVSWAGSQRPSHLSPPLSLLPLTPPPPLFLSLILCFPPPSLSHSPSPSLLSLPSFPVSHSSHSSHSHSPLPQGRRGYRRCPWARLSTPPTPPSGWSSLSPSTTPSSTSTARMRSRTLTCNHIPSVFEHIIAYAPPPLHIYNTIPLHIGLYVPLSPSLSLLLSLFFTIPFLHNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQR4</accession>
    <name>A0A423TQR4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine-rich protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001338">
        <property type="protein sequence ID" value="ROT78762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQR4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="570"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="603"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="615" mass="70731" checksum="FF4B67CB21026B28" modified="2019-05-08" version="1">MLFTLQPSPHRPRTTTRQPNRPRHTRLPDNQTVPAHTTDSQTVPPHTTTRPSPAHTTTRHQNRPRHTRLQHDYRPRHTDSPATHDYQTAKPSPPHTTTRQPDRPRHTRLPDSQTVPATHDYQTAKPSPPHTTTRQPDRPRTHDYQTTRPSPPHTTTRQPDRPATHDYQTQTVPATHDYQTTTPSPPHATTRQPNRPRHTRLPDSQTVRHTHDYQTTKPSPPHTTTRQPDRPRHTRLPDDKTVPATHDYQTTRPSPPHTTTRQPNRPRHTRLPDNQTVPATHDYQTTRPSRHTRLPDTQTVPATHDYQTSPTHDNQTVPATHDYQTTNRPRHTRLPDNQPSPPHTTTRQYRPATHDYQTPDRPRHKRLQTAKPSRHTQLPDTKPSPPHTTTRPPHTTTRQPNRPRHTRLPDNQTVPATHDYQTTRPSPPHTTYQTTKTVPATHDYQTTNRPRHTRLQTTKPSPPHTTTRQPNRPRTHDYQTAKTVPATHDYQQPDRPATHDHNQTVPATHDYQTTRPSPPHTTTRQPDRYQNRRRPALRRPRRSDSHPQQLAISVGGLVISGRRPLLTHSPAPTAPRGETPTPPPPTQPEWASKMEKKVDSNPKYVTSEANEASSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TR54</accession>
    <name>A0A423TR54_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative retinal homeobox protein Rx1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_002364</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001315">
        <property type="protein sequence ID" value="ROT78903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TR54"/>
    <dbReference type="STRING" id="6689.A0A423TR54"/>
    <dbReference type="OrthoDB" id="6382880at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Homeobox" evidence="6">
        <location>
            <begin position="91"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="3">
        <location>
            <begin position="93"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="282"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="153"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT78903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="369" mass="41952" checksum="E507DEFD9D8A4557" modified="2019-05-08" version="1">METSPSTSAVPQENVVAQLNQLQQTVVSHILQYQAGVMAQFQQLQQQMLSQLTSGTPQTTSAAGVKNNRKRPASSMSSADTREDKLTLADIHCKRKRTAFDQRQYQVLETTFEHNNFPEPIDQHCIALRIKTPYRSIKMWFQNRRASIRKRMSPKEKGVNSAEKTKNASDPDARWYCTLCPSTFISKRFLENHKEAHERETLYCPHCNMGFTHKVLLDTHKISKCSSKTGVDLTHLEEEYSNTAATKKGKIQRVEKSKSSTLTAVNIQSALPLLMLQQLQKQQQEAKQDQSEEQHPIKKEKDAIHVPPLLVAGAGPQKETNNQEDTSQEHQRDCPLTPFPRSCLECICYTLYTLARSSKQATRRCPVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSE4</accession>
    <name>A0A423TSE4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_001927</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Oligomer composed of two heavy chains and two light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001255">
        <property type="protein sequence ID" value="ROT79351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSE4"/>
    <dbReference type="STRING" id="6689.A0A423TSE4"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904115">
        <property type="term" value="C:axon cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098957">
        <property type="term" value="P:anterograde axonal transport of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007292">
        <property type="term" value="P:female gamete generation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048489">
        <property type="term" value="P:synaptic vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000067">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="13"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="906"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="346"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="417"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="596"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="818"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="949"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="93"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00064588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT79351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="958" mass="108939" checksum="4BD06007654313F8" modified="2019-05-08" version="1">MSGEDVEKGNEDSIKVVARFRPLNDSEERAGSKFIVTFPHSKDDSQVSIGGKVYQFDSILKPNVTQEKVYNTAARDIVKDVLNGYNGTIFAYGQTSSGKTHTMEGVIGDPNLQGIIPRIISDIFNHIYNMEENLEFHIKVSYFEIYMDKIRDLLDVSKVNLAVHEDKNRVPFVKGATERFVSSPEEVFEVIEMGKSNRHVAVTNMNEHSSRSHSVFLIQVKQENIESQKKLLGKLYLVDLAGSEKVSKTGAEGSVLDEAKNINKSLSALGNVISALADNTKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNEAETKSTLDFGRRAKTVKNVVTVNEELTAEEWKRRYEKEKEKVTKLKAQLEKMELELGRWRAGESVSSDEQVTIDMEASSTSQQLSQILVPTTVAVDGDAAEWARERERLYQNLDEKDDEINHQSQLVEKLKEQMLEQEELISSTRRDYELLQSEMTRLTDENEKAKEEVKEVLQALEELAVNYDQKTEEVERKSKENESLSEEIVQKQTSLNSATSELQTVKDSQLHQKKRINEMLVSLLKDLNEVGTIIGTSNDAMKNLGDVEGKVEEEFTVARLYISKMRSEVKNLAQRCSTLETAQSTFRGQIDEREKELNECKLLITQHEAKMKSLSQSMKDGESKKRSLEEQVDSLNEEVARLKAVSKVSEQDGHIKEVLEKQIDEHREQHQKQLTTLRDEILEKQQQIDNLKDENQKLTVTEEQVKAEYEKLKAEVVEKTEKLNELTTIHERKEQARQDLKGLEETVAKELQTLHNLRKLFVQDLQTRVKKSASGEETDESGGSLAQKQKIQFLENNLDQLTKVHKQLVRDNADLRCELPKLEKRLRATMERVKALETALKEAKEGAMKDRKRYQQEVDRIKEAVRQKNLARRGNAAQIAKPIRAGHAPQVNHASTPVIRGGMQPYQPPAVQKRAMTSSAHMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYK8</accession>
    <name>A0A423TYK8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025308</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000958">
        <property type="protein sequence ID" value="ROT81543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYK8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="519"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="549" mass="59378" checksum="4E30193E7E085670" modified="2019-05-08" version="1">MHLVLACAEENPETVRYTLHVIIITLLIVIVIILFVLTIIPLSPPLTFLPLFPFLPFRLLSPFPSFPASSPPFSSFLSTSSPLFLPSLLPPPSFPSLSPSSFPPIPSASSPFPFLPFRLLPLSLPSLSPPPPFLPFLSPPPPFPSLPFRLLPPSSPSLSPSPPFPSLIPSASPFPSLPFRLLPVFLPPLSPPHPFPFLPFRPPPPSPHFSLLPPHFPLSLPLSLSPPPSLPSLPPSLSISALLSAFPSVSPFRPPSPLPLPSASPLPPPFPLPSLTASSPPSPSHSIPPPLRLSPPSPSASSPPFPPLPLPPPPPLSLPSLPPPLRLSLLPFRLPPPPFPPFPSPLSFPSLPPPHQESLAPAWHLEVFRVFYARAARTHCSVSSFFSYLPCLSCLLLVSPFLPFVLLPHFFSSLPLPLIQYSSSLFHTLPSSSCSFINPNPSPPPPRFLSFLHLLFALLLPPLSCSTLHSSYFLLPLPLLHFLSLSLSLFISSSSTLLLSRSSLPSSFFPLFLHLRLQFLVPFLLATLSSSIVPLSLLLLLLNCLPPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U020</accession>
    <name>A0A423U020_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat and SOCS box protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024812</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000894">
        <property type="protein sequence ID" value="ROT82024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U020"/>
    <dbReference type="STRING" id="6689.A0A423U020"/>
    <dbReference type="OrthoDB" id="9995210at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070531">
        <property type="term" value="C:BRCA1-A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031436">
        <property type="term" value="C:BRCA1-BARD1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="64"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="97"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="20311" checksum="C542B31922A5E912" modified="2019-05-08" version="1">MSCVTATHSIHIISFEHPLLFFLCSHYYFTLSHVQQRDLAGAGDGQALRSALASLPPRAKKDFLGRHLLHEAAEEGREEVVEILVEAGADVNAKGSEGRTPLHEASSSGQEGVAEILTANGADLNAKTDDGSTPLYLASLNGHVAVVETLARKGADLDEKKSEGFAPLHRAAQYGHVEVIKLLPPRERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4T8</accession>
    <name>A0A423U4T8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000646">
        <property type="protein sequence ID" value="ROT83692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4T8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="52720" checksum="A27EBBD381FAA081" modified="2019-05-08" version="1">MAHEAGRRPSGDRQASKASSTTRTSMSGLLPSPVVCGDEPSFVTLYQNGGSKRLVEGYDASAKYNGSSRQHENGGRLGLANGERSSDSEDSGATSGATSGKEASPGYEESSGSEQSSGPPLSEENRGDDEMDPEPRLVRSALPRSQTTPVLNGDHTLDDVLRPLTHYGQESPSSESSRLSSDLSRIRAAHEINISKLAYLEALFQRAKLEEMRLKNLNASRETNEARSAKSGSKSLQSPESGYKSLPSSVSDYGLRNYGSGHSSSSTNNSSCGSTLPDGQALLRTIENRLQLARPQEKSSSRSLYQCGGSSSVGSLSRLATGHSPATSGTSTPARFVSPSRSEAHGGSQGTTPGSTPATTPGGTPKRPEGLSQSRSMGHVSQRSLPHNYRSRSAYSSPAVSPQRGPDPAGFLVSPSGGVPNTRRFSSLDLRGRGQPRQLSLRHTAHGYPTVVLPISPPSPAQGTQAFHRKMQLFFEIMDTQSRFSQVGAVSQALASIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBC1</accession>
    <name>A0A423UBC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proton-coupled folate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_022557</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000057">
        <property type="protein sequence ID" value="ROT86012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBC1"/>
    <dbReference type="OrthoDB" id="6363752at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="628"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="668"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="789"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="377"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="555"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="408"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT86012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="89847" checksum="7277064E030AA48D" modified="2019-05-08" version="1">MALISAEPTIFMYMASYGILIILSQDFILSRLCFAQLGDPDCGNSSTPSASSQTSPSSFTSPLHFYPNPEGEWTPVGETADQNSRAREVQEEAVRLYMGATITLSVTSILSCSKKVLMIAPVVCMIMWALGIVVLATFPQLPIYLIFIAIAIGNISGGYVTLKSAVTSYVIQKSPESQRTVRLSMLEAAIFLGGAVGLLSLPFLTDYLGATHAVLFLGAEGLAVINFLYIIFILPDDGGSPRSSNVGEDEVDSPGQSPPSDHNYGTFQGTGHSVLSQGSHITASRHTVADIIETSPEGEDCGDYSVLPVSLRGGGSRSGTPPELTVKPESPDNHSPYGTPTPDMFSQENYLHARHALSAAFGIVTSVAGMSNPASRYGTPPEYPSDLQYVPGDVSEDVGRSRSRSYPAPNSTPISVQQRSAKACEVKAGVVKGVSMRDDLLTSRWGERVGFERAVDEVDSEEAPNTSGRASSSLYPEIMTVTHSFCLTDDSSHCSDDHRSHCTDSCISDVSHPSFDHCHSDGWLGDGHCPDGDHCHCDDPGDACDGQVIPRAFTRDPQRPASSESLYHEANAKEEKGYEKLKEEERVSAITQAKGEKYEREDDGEHDGVFGRLLDALRTTFRYRPNGVRNMVVASVIANFFISFVVPAESDVIFLYVKAKLGWSFTRYATFFALKCGVDGVALLLLLPLLRRCLGLRDASLGVLGGLSRAAYFIVLGSAYKPSMVFGALVTAVFGQYLFVSVRAIMSSLVGENEQGRVFTVLSSVDQLAQLFGSLAYDNLFPVFLTKNMPGVTLMLAGLAALIPTVIFGVLYFNLDNATGKKRSEVRPLLADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUT1</accession>
    <name>A0A3R7LUT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_017110</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003165">
        <property type="protein sequence ID" value="ROT64951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUT1"/>
    <dbReference type="STRING" id="6689.A0A3R7LUT1"/>
    <dbReference type="OrthoDB" id="6364703at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11056">
        <property type="entry name" value="CYP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000042">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002402">
        <property type="entry name" value="Cyt_P450_E_grp-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF104">
        <property type="entry name" value="CYTOCHROME P450 308A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00464">
        <property type="entry name" value="EP450II"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018716829" evidence="15">
        <location>
            <begin position="19"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602402-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT64951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="496" mass="56064" checksum="BBF4BC3F35F3B5CD" modified="2019-04-10" version="1">MSLVTLALLCVAVAALWAYSKWRHSYWASRGVPTPPYVPILGHMHQALSKEGKWKYDSVAYHKYGGSKFCGLYEFFTPVLLVGDPDLLKHILVKDFDHFVDRMTLALPHEKDKMTAQMLSLKKGDEWKQLRAIMSPTFSSGKMKGMFPLVCEKADAFVAFSLNDSRGKPYVDMKYNFGRFTIDTIASCAFGIECNSLVDEDAEFPKRADKIFEATPFDILKFLFMNTLPSLAKLLNLRFTHPEADFLEEVVRHTIKERMKGERRGDFLDLLLEARNPDGAAKEVKETGVDSTTKSKYLLDDTTIASQCMLFLIAGYETTATTLGFAAFQLAKNPSAQEKLRQEIQDLVHEEGDITYQGVMEAKYLDACLMERICTRDYRLPGTDLTIKAGDKIQCPVWSIHHDPKYWPEPNEFRPERFLPENRASMKNFAHMPFGIGPRNCLAMRFALMEAKVVLSKLLLAGELHPAPGHEEIVLEPGIFGIIRVKGGVKVTLKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LV59</accession>
    <name>A0A3R7LV59_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003350">
        <property type="protein sequence ID" value="ROT63951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LV59"/>
    <dbReference type="STRING" id="6689.A0A3R7LV59"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="41286" checksum="FFA977D753AA6C36" modified="2019-04-10" version="1">MSHCARQIASIYGTAPCSEDAASPISPIAAGYRFRNSVGRSTTPHPVAKGRSMTLPPAAGGPLTPPPAAEDLSRHQQQKDLSRRLQQQKDLSRRLQQQEDLSRRHQQQKDLSCCHQRRRTYHAATSSGRTSHAATSSRRTSHAATSSRRTYHATNSHAATAAEGRHQQQKDLSRRHQQQKDLSRRHQQQKDLSRHHQQQKDLSRRHQQQKDLSRRSRRTSHATTSSRRTSQPPPAAEGPLMPPPAAEGSLTRHQQQKDLSHRHQQQKDLSRLSHAATSSRRTSHAATSSRRTSHAASSSGRTSHAASSSRMISHAATSSRRTSHAATSRRTSHAATSSRRTSHAATSSRRTSHAATSSGRTSHATSSSRRISLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYI9</accession>
    <name>A0A3R7LYI9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002900">
        <property type="protein sequence ID" value="ROT66715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYI9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="238"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="350"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="465" mass="51289" checksum="416FF8699783D5D8" modified="2019-04-10" version="1" fragment="single">FPQPFSPPFLRPSYPPFHSYSTSYISPSLHPSALLSSLLPSLPPPFRSSFSTSYPPLQSFYSPPLPLPFSPPIQRPNPPNSTPPITCLSPRPSASPPPPPSPIHPPSRPSALLSSLISPLPPTLQPSYPPSPHPLSPPIPPPSHPSTLPYPSNYLPLPQPSYYTPFPQPSYPPPIPPSYSPPTPSPSPPFLFAPPYSPLPPVPPEVSCVTDRRRRFSPNPRDAEWAAVSDVTAHRESLVYFLLLPASCFLLLLFSSLLILLLTLLFLLFSSNSSAHVLFPSPPPPFLFNFFFSIPSPLLFSLSSTHAPLLLPSWSFSLLILPLTAPLPPLPVSFFLFLLSPVSRSPFSAFFHPYASSSSFSPLIFLLPPRAPPHSFFKIPTICTTGSIFSFSLSFFPFRGRQFMICQVISRCNQLLSRRICTSKAGRRRTLLPGTVARPPPQAAAFQPRFSRDASPRRRPRPRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYR0</accession>
    <name>A0A3R7LYR0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Receptor for egg jelly 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002717">
        <property type="protein sequence ID" value="ROT68129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYR0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="192" mass="20712" checksum="8327F31EE191778D" modified="2019-04-10" version="1">MRYCKSYGAAMFLPQNSGENAFLASFKRTKWLAMKKTDGIFVNAVTGDPVVYTNWKDGEPSSDNLTCVYMDLQGFWVGADCSDDFSFTCTIPIATSYLLCWCICVHSTSREIFSSSSMLSVHLLPPAASSSVQERTASSPSAASELGRSFALVGVSSLTARTARPSAHQAEPALPRPQGTGSPHRQRPSLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZK4</accession>
    <name>A0A3R7LZK4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Methylmalonyl-CoA epimerase, mitochondrial</fullName>
            <ecNumber evidence="7">5.1.99.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">DL-methylmalonyl-CoA racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014361</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:20553"/>
            <dbReference type="ChEBI" id="CHEBI:57326"/>
            <dbReference type="ChEBI" id="CHEBI:57327"/>
            <dbReference type="EC" id="5.1.99.1"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:20555"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.1" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01002801">
        <property type="protein sequence ID" value="ROT67539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZK4"/>
    <dbReference type="STRING" id="6689.A0A3R7LZK4"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046491">
        <property type="term" value="P:L-methylmalonyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.180.10:FF:000003">
        <property type="entry name" value="Methylmalonyl-CoA epimerase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051785">
        <property type="entry name" value="MMCE/EMCE_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43048:SF3">
        <property type="entry name" value="METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13669">
        <property type="entry name" value="Glyoxalase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="10">
        <location>
            <begin position="48"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00050406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00053742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00066411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00081771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="177" mass="19335" checksum="0E66AB2E52290D6F" modified="2019-04-10" version="1">MRSMRPITQIVSRLSGMGGLSSRLISHSAVIYQSPQTKVPAALWKLGNLNHVAIATPDLEKSTALYRDVLGAEVSEVEALPEHGVYTVFVKLDNTKLELLHPLGENSPIQNFLDKNKNGGMHHICIEVNDIKSAMADLQAQKIRCLSKEPKIGAHGKPVVFLHPKDCAGVLVELEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2M0</accession>
    <name>A0A3R7M2M0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Putative alpha-L-fucosidase</fullName>
            <ecNumber evidence="5">3.2.1.51</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alpha-L-fucoside fucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_010472</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:0) + H2O = a neolactoside nLc4Cer(d18:0) + L-fucose</text>
            <dbReference type="Rhea" id="RHEA:49308"/>
            <dbReference type="ChEBI" id="CHEBI:2181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:91119"/>
            <dbReference type="ChEBI" id="CHEBI:91121"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:49309"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O = a neolactoside nLc4Cer(d18:1(4E)) + L-fucose</text>
            <dbReference type="Rhea" id="RHEA:48224"/>
            <dbReference type="ChEBI" id="CHEBI:2181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17006"/>
            <dbReference type="ChEBI" id="CHEBI:28691"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:48225"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the glycosyl hydrolase 29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002329">
        <property type="protein sequence ID" value="ROT71220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2M0"/>
    <dbReference type="STRING" id="6689.A0A3R7M2M0"/>
    <dbReference type="OrthoDB" id="6039950at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000027">
        <property type="entry name" value="Alpha-L-fucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031919">
        <property type="entry name" value="Fucosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018526">
        <property type="entry name" value="Glyco_hydro_29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030:SF37">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16757">
        <property type="entry name" value="Fucosidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001092">
        <property type="entry name" value="Alpha-L-fucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00385">
        <property type="entry name" value="ALPHA_L_FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 29 N-terminal" evidence="14">
        <location>
            <begin position="15"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-fucosidase C-terminal" evidence="15">
        <location>
            <begin position="361"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="site" description="May be important for catalysis" evidence="13">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00074133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00081661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR001092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001092-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT71220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="52073" checksum="553FD6C41BCCB2E7" modified="2019-04-10" version="1">MLRTLQQQDSDFGLAGAKYEPTWDSLDSRPLPAWYDAAKVGIFIHWGVFSVPSFGSEWFWKYWHDGKGKYVEFMERNYRPGFTYADFAPEFTAEFFEPEEWASVFNASGARYVVLTSKHHEGFTLWPSRYSWNWNSLDVGPKRDLVGDLAQAIRTKTPHIHFGLYHSKYEWFNAMYLEDKARGFETQDFVKAKTLPELYELVNTYEPEIVWSDGDWEAPDSYWDSTHFLAWLFNESPVKDNVVVNDRWGKGVVCNHGSYYTCSDRYNPGTLQHHKWENCLTLDKVSWGFRREAPLRDYLTIQELLATLAETISCGGNLLVNIGPTHDGHLPAIMEERLRQLGSWLDVNGQAVYESTPWTHQSDAVTPGVWYTAKGDDVYAFVLRWPEDGAVTLGSVLPTSRTKAYMLGHVEKVKPLQFTKTEKGQLTVMLPLMHQVRGQWAWVLLLSDVMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5I4</accession>
    <name>A0A3R7M5I4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nicotinic acetylcholine receptor subunit alpha 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002137">
        <property type="protein sequence ID" value="ROT72555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5I4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="11983" checksum="A0C8CC417529EF69" modified="2019-04-10" version="1">MVSVQVLRLARGPRSTGLSSCIRRPLSALASCLFLGNYGAMVKNDHPSPKDDLKKHYDQPPQYSQLSGSSETTGRDDYVVLAAVVDRLLFLLFLALCLNNVIRFWSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6N9</accession>
    <name>A0A3R7M6N9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002656">
        <property type="protein sequence ID" value="ROT68574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6N9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="628" mass="67248" checksum="0DED20FF3F71AA98" modified="2019-04-10" version="1">MASAKKVRRGGRGRPHDAFFREVRTPIRAQGTAGVGGLRDASGHLLPSKSGRPSATARPHARSPFHTIFVIDGSGVNRTSLLHRCLSLSLSPLISLSLVLSPLMRNSTVHVIIGKLPPPLSIPLPPPFHLSPLSLGLPFPLLPSASRTPSSSLPSYTSPYLPSSFPIPAPSYSSPPPSFHTLSSSSKHPSYPLPLPPLFTTPLYYPQRPSYPFPPLPLSPHPTKPPFYPSPPSPPSFQHPSYHSLLQTFSPSPQVPSPLAHAFPLSPLPSLPFLSFPSPPSSPNTLSYPFSPPPLLTLTPTPFPLPLLPFPSPTPPFSPNTFLPIPSSTPSHPHPKSLPLSPCPSSSLPIPFPPTFPSPHPSYFPQHPFNSLSSPCPSLPSPTPSHPHPTSFPLPFPSYPFPPPSLPSLPTLPPPPLLLPQHPLLLHQPPSLTPTPLLPPTTLLPLSPCPSFPLPHPSHPHPKLPSPFPSPPPLPFLPFLPFPSPTPPTSPTPSLLHNPPTPNPNTPPTPNNPPSPLPLPFLFPSPTPSHPHPNSPSPFPFPLLPFPPPSLPSLAFPFPLPPLLLPPTPLLLQHPSPSPQLPPPFPSPHNRRSPVLTYGVVVYPIVLRFEAVSGALENSPTRKTSDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7A9</accession>
    <name>A0A3R7M7A9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7A9"/>
    <dbReference type="STRING" id="6689.A0A3R7M7A9"/>
    <dbReference type="OrthoDB" id="510539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018756831" evidence="1">
        <location>
            <begin position="40"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="2">
        <location>
            <begin position="76"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="231" mass="26150" checksum="C4BDA31368A5D58A" modified="2019-04-10" version="1">MDAGVRRFCNSQCSLESLLPQAVRMLLFVLLALGHATQGLPNVDDVTIPPWVTTTTEASRSLGPVDLDVQLPRSIKPLHYVVKLQPFINGNFSIVGYMEVEMEVLEPTSNITLHISDIITKNDTVKVSDQATSRGLRIKKHEYDHSRHFYIAHLRKELQKGKRYILSMEFLGYLNDKLRGFYRATYKDVDGNIRNAAATQFQPTDARKAFPCFDEPALKATFEIHLARESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M859</accession>
    <name>A0A3R7M859_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Interferon regulatory factor 2-binding protein 2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_006802</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IRF2BP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001861">
        <property type="protein sequence ID" value="ROT74688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M859"/>
    <dbReference type="STRING" id="6689.A0A3R7M859"/>
    <dbReference type="OrthoDB" id="10065080at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16511">
        <property type="entry name" value="vRING-HC_IRF2BP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1580:FF:000001">
        <property type="entry name" value="interferon regulatory factor 2-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1580">
        <property type="entry name" value="Interferon regulatory factor 2-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044882">
        <property type="entry name" value="I2BP1/2_C3HC4-RING_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022750">
        <property type="entry name" value="IRF-2BP1_2-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057414">
        <property type="entry name" value="Zf-C3HC4_IRF-2BP1_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10816">
        <property type="entry name" value="MYELIN TRANSCRIPTION FACTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10816:SF19">
        <property type="entry name" value="PROTEIN INTERACTING WITH TTK69 AND SIN3A, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11261">
        <property type="entry name" value="IRF-2BP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25454">
        <property type="entry name" value="zf-C3HC4_IRF-2BP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Interferon regulatory factor 2-binding protein 1/2-like zinc finger" evidence="5">
        <location>
            <begin position="15"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Interferon regulatory factor 2-binding protein 1/2-like C3HC4 zinc finger" evidence="6">
        <location>
            <begin position="273"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="169"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="222"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT74688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="39543" checksum="4F9E1D1C8E15C67F" modified="2019-04-10" version="1">MLSESRGNMSSFRSQRQHCYLCDLPRMPWAMLHDFSEPVCRGCVNYEGADRIDLVIEAARQMKRAHGINENRQGPPSKPHPRVPIEAQNGAHHGPIKLEAGIKMEPGSHSHAHSHGGHPTHTAALPPPGTPGVAFVAGDVRQRGPHMLAFPAGLPHRDDPHAPALKRSFERDDAQSPSEGSVPKRPMLEESHRPPLTRGESLPAPPVAANYKDAAKHHPVRVWSFDGSSSKPPAGEPRRRSSGGRHGDSSGDSSPGAQGSGAGNEGSQPSSNLKCTICTERLEDTHFVQCPSVLHHKFCFPCSRDSIKRQGAGTEVYCPSGDRCPLAGSSVPWAFMQGEIATILGTANILPQHSQDEAKTKKERDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MA49</accession>
    <name>A0A3R7MA49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative WD repeat-containing protein 61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_005145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MA49"/>
    <dbReference type="STRING" id="6689.A0A3R7MA49"/>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="122"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="164"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="206"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT76251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="255" mass="27788" checksum="56E69EC8ED4B63AD" modified="2019-04-10" version="1">MKKKEQRYVVSGGLDDLVKVWRWTGDGVEGELSAMHTLEGHSLGVISVDVNAEGTMAASSSLDSTIRLWNIHSGEQLQTIDCGPVEAWSVVFSPDGNHVASGNHAGKINVYAVDGGRHVTTLDTRGRFTYSVAYSRDGKYVASGAIDGFINVFDVESGKLVHTLEGHAMTIRSITFSPDSQLLLTAADDGHMKIYDVKSSHLACTLSGHGSWVLSVDFAPDKMHFVSSSSDHTVKVWDFAQRNCVHTFKDHHDQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ME48</accession>
    <name>A0A3R7ME48_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001146">
        <property type="protein sequence ID" value="ROT80173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ME48"/>
    <dbReference type="OrthoDB" id="10006218at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF10">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13383">
        <property type="entry name" value="Methyltransf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="155"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="44569" checksum="69C80735F63589E8" modified="2019-04-10" version="1">MGNRRRKPIQELHADDDVAKSKYSLFSCVLFHVRRCLTSLNTLKMARASLSRRLRLAILSVLCFVLVLYVRPRPLLLTPTPALTRVATERYEEERTPPADETLTTAPVFGHNTSLAGHELEEQLVLLDQLLLLMSNVTKPCRKLVRQGGKLCRGKLDGDKKLCLDPIVRPTPNNCLVYSFGIGYDFSFDAAMGKYGCQVFSFDDDSAHELLDRNPYPRVKFLRLRLATGRGVKVERSYNPKTKSEYIYLYRPLDNIMYLLGHHEANVDVLKIDVDGPEWEIFEDSIFKTDILERTRQLSIEIHLSVFLNPNLDTGHPLTRTLHKYTRVFRGLEDRGFRLTHHEPNLFYPNFLNALQMAPTSLSRRLRFTVLSVLCSVLVLCAKPRPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFU2</accession>
    <name>A0A3R7MFU2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_025367</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000968">
        <property type="protein sequence ID" value="ROT81466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFU2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="359"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="529" mass="58102" checksum="DA639EAB038C83D5" modified="2019-04-10" version="1">MYVHRRLFVHFSACFLPSLFLPSSPSFFPRTSYLFSPSIFYSSSNHIFVLFLFLPVLFFLFLLPASSPLSSSLLLILFLPSFSFLISLLSSLSSPPTSPLLLLLPFPSLLLPPTSCHFLPPRLPPAPLPSPASSFRPHRIPRAGCWLGDPLHKTPLRLDGINPEGRLLLFCWGSSFLLRSFSLALSSALSFALSPPSLFVVCRPVLLRLYSLSFALSPPSLFVVCRPVLLLLCSFSLALSSALSFAPSPPSLFVVCRPVLLLLSRSLIFSLSVFLRLLSSWYVVLSCSFSASSLSFSHLLSFGPSPPSLFVVCRPVLLLLPPSSLSFSHLLSLSLLLHLLSLFSPLLSLPYSSASLSLYLLFPLILVSFLSLSFHLLLSSLSFFLLSLFSLFTYPRPLPSPFPFLPSFLFSLTLSPSLPLLSSQSLHSLCLPCPSPSLPSTFLLSFIHFILFSAYGQPPTPLPNPSLIPLPTPPQPLPTLPQYLSPPLPNTSSHAPQPLPPLPRLPNPQYLSPPPPPQYLPPCFTNRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MG11</accession>
    <name>A0A3R7MG11_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_006070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001777">
        <property type="protein sequence ID" value="ROT75394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MG11"/>
    <dbReference type="STRING" id="6689.A0A3R7MG11"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1540.10:FF:000016">
        <property type="entry name" value="Derlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT75394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="222" mass="25786" checksum="3DCB3F19FB24AF23" modified="2019-04-10" version="1">MAHQTFPSNKNIYRCPQLHGLTTSCVATTILVQLDLVSPFQLYFNPLLIIKHYQIWRLVTTFLFFGYVGFNFLFNMIFTYRYCRMLEEGSFRGRTADFVIMMLFGGACMLCCSMFCSLPFLGQAFTIMLVYVWARRNPFVRMNFFGLLNFQAPYLPWVLLGFSVLLGNSILVDMVGIAVGHIYYFLEDVFPQRSGGIRLLKTPRFLFTESPSLWFWVASLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIL9</accession>
    <name>A0A3R7MIL9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative E3 ubiquitin-protein ligase MYCBP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000789">
        <property type="protein sequence ID" value="ROT82679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIL9"/>
    <dbReference type="STRING" id="6689.A0A3R7MIL9"/>
    <dbReference type="OrthoDB" id="6050183at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008582">
        <property type="term" value="P:regulation of synaptic assembly at neuromuscular junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45943">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MYCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45943:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MYCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="55231" checksum="AF587A1BDFDC5BCD" modified="2019-04-10" version="1">MVPSLTDASTETFWESGDEDRNKTKALTITCAAAIRPQTVYVHIDNCRDLGNKVSSVVFKCGPSGDDMVLVRQVDIESRFSGWIHAVLPHDVITTIVVELRGPDQSVRVRQVRVLGGEGGEGSGSRPLRQHSPLTIQHRACEQETLKVFRLITGQVFGRLIMTAEGGSKAAEGSDGTAGNIENVDEQDHNNDLREHMVGILFSRSKLTHLQKQVCSHIVQAIRKEAVRAREEWESGLNCGGLGTPATPEEGQHNPPDTYCFEMLSMVLALSGSVVGRAHLAQQDHLLKHLLSLLHTGSARVQRQVVALFRRMLADVPPQSLALILGVEALPAHDYAILHATSKDEENNFDIHQQGILDVFLAVIAKALTVQLKTKGGEGGKSVATQGKGAVTSVSLASTMPTPQANSPRWWLQGSATQKQADLIISLIRDMTTGKLSDNWAKVSKGAIAENIVNLTRLSESDRSCAASCLATPTLWLALASLCVLHPDHVDALSSWHHRGGIHITQSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJI4</accession>
    <name>A0A3R7MJI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_023417</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000688">
        <property type="protein sequence ID" value="ROT83412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJI4"/>
    <dbReference type="STRING" id="6689.A0A3R7MJI4"/>
    <dbReference type="OrthoDB" id="6375714at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019594">
        <property type="entry name" value="Glu/Gly-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10613">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00918">
        <property type="entry name" value="Lig_chan-Glu_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="395"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor L-glutamate and glycine-binding" evidence="14">
        <location>
            <begin position="227"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT83412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="597" mass="66448" checksum="6D3A91D33102E9C4" modified="2019-04-10" version="1">MALLTISTGEPLTSPLPKLNYSKNSNRDSSEDRRVVQSLLEVTLKDICRGPLAGRDVSLVLDASCGENMLLPEFTEALGVPALLFHGEGADREVLEAAKRNRLDAVVSVVGAELPWLLTSPPERWSASSVLLVGNTLACDPRALLQTALAQRTPAVAALCLAKLGEQRNKLEFRVFTWRPLHPRRKLLPLGGWNASRFASWDQLFVDRFSSFGGVTLGVASDHEDKPFLFNSSLTEWEGVGYRILKTLAESYNFTYTLTPWASDRRWGNWENGSWTGMLGDLYREVKNLTVNIISLSPRRAQYFDISVPFYNEGFSFALAFPPPPPRWYSLVHPFSWTMWAVVGGVLVVVCLAYWFLASFREKASPSVYLLTIAQALLNQSNSSVPASWPLRLFLASWWVTAYVIVMSYTCNLIAFLTIPASPVKLESVQQLANSHHRLCMLDYGSYLPDALATSSHQSLSALGKKMDLVPQKKAVPYYNALECVDLALAGSHAMVEAESYLRNLVESEDLENKMYFLEDSLFEGALALFFRKNTPWKYKFDKGGTEKLGVAKPGTPLHQDQPIPFKCHHAGASLHTALTRYIASVPEGWTQKISAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML43</accession>
    <name>A0A3R7ML43_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017544</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003242">
        <property type="protein sequence ID" value="ROT64516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML43"/>
    <dbReference type="OrthoDB" id="6371339at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="3">
        <location>
            <begin position="298"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="43792" checksum="5600B1D52B108C68" modified="2019-04-10" version="1">MWLGGAFFGQNNVGHRPTEHNRNHNEPLPGTMMMAGAEGSDSSTEPELSEAQIQAGRPLLNCVVAGTKVLAFLDSGRGHLGHLGPKGIKGRATLEFKFSRACKCRHSVFVVDDDTRFPAEVLIGVDLLRRFNFKLNLSPVSGASSASFNEVRLGVSFSGAGTGVNPPMTFAHGLNDFGYNMDEFEVFLVCSFENEELPSSAGAVGVPRVDLAHLSSVQREQLVQIAAIADLDSPLLQPDLVERHQRDDPLWQQLIEYLEEGRLPPRRIPLPLDQFELRDRVLYHVKSNNERAMLQLVIPRSLCGAALDAVHAVPSAGHQGVHRTYQRLRDHFYFPGMLAASRRYVASCTACQRRKGRSPELPYSPCRTSRALRAGVRGYPHSYPFGAWKQIRPCAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML56</accession>
    <name>A0A3R7ML56_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000199">
        <property type="protein sequence ID" value="ROT85743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML56"/>
    <dbReference type="OrthoDB" id="8912589at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39948">
        <property type="entry name" value="GEO11419P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39948:SF1">
        <property type="entry name" value="GEO11419P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="201" mass="21896" checksum="68AE20387F6FF038" modified="2019-04-10" version="1">MAIESALKGPSQASLIRDLTPSRKRSLPRRGIHLFPAETLMLDLLARGRRHLLAELPTSPNLAQPIPVETLGEATRRHGLLVKNCVHVCWGQSVGGESTCCTPGRSETGTTGSGGTLWLVIWLLLLVFAALWVAGFCAWWYIMLIPFTVCLPPLAAVTDVLLRGTQLTYFCAKNMMDRNNFNEAMANAATTVPPTVLVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML84</accession>
    <name>A0A3R7ML84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001188">
        <property type="protein sequence ID" value="ROT79779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML84"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="40821" checksum="210EB34E543A946C" modified="2019-04-10" version="1">MMKSEKTQSAENRHKTGKEKQQREKPKGREWRKGERTVDSHNKDGLCSGAAWEVRPPRPPASLPLTLIRGSLLRDPSPAFCSFHGRTIPPSFPSHSPFPVLLCSSLPEVNAFIYSLSLPPSPPTPPSPIFQFPLLPLPFPLSLPPSSPSTLRLSHPPPLPSSPPHLPPSFLPLLIFLPFPFLLLFSPPPPPPPLPLSHFSSFLVTPLIRYDFRTSSVSPSYRDAAARGSDASPATEVLLTRTPLYGPSASLPNYELLINVCICIPSSPFPLPPSPFPFSFLSLSLFPCPLPLFSLYLALSVPFSHSPLPLSFPFPCPLLSLFPLPSPSNFPLPLPSNFPLSLPSPSDFPLSSPSNFHLSLPSPSPLSREPPSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLZ9</accession>
    <name>A0A3R7MLZ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001122">
        <property type="protein sequence ID" value="ROT80436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLZ9"/>
    <dbReference type="STRING" id="6689.A0A3R7MLZ9"/>
    <dbReference type="OrthoDB" id="6381127at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="224" mass="25875" checksum="9C964DC73561D889" modified="2019-04-10" version="1">MDLMGPFPLTERGNQYILVIVDFLTRFAVVRALPNKYAETVAEAVSEVFADLGIPQTVLTDQGREFRNEILKEMAKHMQFQHHKITAYHPASNGLCERTNQQVLNILRGMVDGKDQYWDLYLKDTQMALNSAYHKAIGDTPYYAMYNRDLKTSDLWWTRPTSFGGPPDEDFITARTQRSKEVYEYVRDNLLRAADEQCRIRQKKSKDTTVLPGMRVFIKAVKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MP36</accession>
    <name>A0A3R7MP36_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative gamma-butyrobetaine dioxygenase-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_015423</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002918">
        <property type="protein sequence ID" value="ROT66544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MP36"/>
    <dbReference type="OrthoDB" id="6341042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="3">
        <location>
            <begin position="66"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT66544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="17169" checksum="1A03B290F5EBD4D0" modified="2019-04-10" version="1">MSSQRYTKALLSGATAFRSVARQQVRHNSQVCMHSRSLSLAAAARNQLAVLEAPLPGTGVVAAVTGDKSLRIKFSDGSAREVPYTWLRDNCRCHACSGTLASGNLHSEVYPEIIQSNEFGVVVDWSDGHISKYSGLWLHDHTLMSPPRTLNRILHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPS0</accession>
    <name>A0A3R7MPS0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transmembrane protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_024182</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in mitochondrial morphogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TMEM11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000791">
        <property type="protein sequence ID" value="ROT82650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPS0"/>
    <dbReference type="STRING" id="6689.A0A3R7MPS0"/>
    <dbReference type="OrthoDB" id="9970856at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026120">
        <property type="entry name" value="TMEM11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15099">
        <property type="entry name" value="PROTEIN PM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15099:SF2">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14972">
        <property type="entry name" value="Mito_morph_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16007" checksum="0C327E9881CDA92F" modified="2019-04-10" version="1">MELERALEAGIHTIVIEPTTLGDETARWIAVGNCLHKTAVLAGFGSIVSGLIWRDTAYVCVPLGTLSLFCTGVYTASWQFDPCCKYQVEYDSGRLSRLPLQSLSSASPIVLVHKDDSRRKILHNCVSLVAFSYCMWRLYQLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N903</accession>
    <name>A0A3R7N903_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Estrogen sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_000732</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N903"/>
    <dbReference type="STRING" id="6689.A0A3R7N903"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="4">
        <location>
            <begin position="155"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT80496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="481" mass="53879" checksum="A7F7F2AC9E1978EB" modified="2019-04-10" version="1">MLNPVPMADLGCSPSPSRVALLDREPGHACAVRVLTVSSPSLSLIGRTRGSGRRRDPRVQPTRHKSNNEWAAAPNSRMAKGSAASPGHLMTEEGEGPAGGCPVRVKELPPGEEARLVTLGFKGYTGLVRTQPGGMLMKARYKEMAPRFYNFAFRPDDIVVMTYPKCGTTWMQEILWGMTHLDELDEADRLPITKRTYFIDSDALYQLEDQMKDRFLMERFRALCPSARPDRGILLQSCGAQPPHPSKPRIIKTHFPFSLYRPDLLDRCRVVYVCRNPKDACVSYHHHCRLINTYKFEGSFETFAGCFMAGDVFYGRFWDHVAAAWERRRQPSSALRLLRGPPAPGPATASETLAGLGSLRSFALRQGSPYPTLGNYTRNDHPSSFYPSYTRPYLLPQNPSAISRPYAYSTRPLRTSQARTHLIDCPPYFTPPFTPPFLMPLLTPPTSPPPLLRPLIQRSPLSPLDRPLTPQPILAFPSFTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NC40</accession>
    <name>A0A3R7NC40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Antilipopolysaccharide factor isoform 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023656</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000725">
        <property type="protein sequence ID" value="ROT83164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NC40"/>
    <dbReference type="SMR" id="A0A3R7NC40"/>
    <dbReference type="OrthoDB" id="6355162at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024509">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038539">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11630">
        <property type="entry name" value="Anti-LPS-SCYG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0044">Antibiotic</keyword>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="46059" checksum="07754A4183EEE585" modified="2019-04-10" version="1">MNVHVNVTGQKPHPFPLPPPSSKAPPLPPLLVTLLPPPPCLTAPSTLPEPTLQPSKNAPHLSNGFILSMPSHPLQHTAPHLSPSPPIFFSRTFLIPLFPLSHPTLPPIPPRTSLSTSPPLPNAPHLPQNRSPFPPTTRSSSLPTRPLLYNPLPPIPPFHIPPNNRFPRETSQIAPPAPLSSQRSPSLPTRIPTLYQMFPSFPSLPHPLHLHPARVRKQMFSRRAISPRSHKKRNLRFARPLTRTSHSREPCRKIAYKTGFPGRKFSVILRASHWTHAGTKSSVNCFVTRDKMAPTTSSRVAKFSIICFLLFASVSARPQLGDVLGSVVETFLKNAVKTSELTILDNYCYVNRSPYLKKFEVHYRADVKCPGWTIIVGRGSDHTNPTNSELDAIKDFVKQAVIKGIMTDVEAAEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NZH6</accession>
    <name>A0A3R7NZH6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative cell division cycle protein 16-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_010525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002333">
        <property type="protein sequence ID" value="ROT71193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NZH6"/>
    <dbReference type="STRING" id="6689.A0A3R7NZH6"/>
    <dbReference type="OrthoDB" id="10006270at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF9">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12895">
        <property type="entry name" value="ANAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="330"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT71193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="439" mass="48711" checksum="B397315D96E45F78" modified="2019-04-10" version="1">MHRTPSATTRVPLFVMRHTGREWTSGFGPSANGAAPWRSPGEARAKIKSGESIDLEKFRKLVRSYIERHHYKAAVFWADKVVSLSNGSPADVYWLAQSYYLTKQYHRAILLINGHKLTRNATCRYLVALCYYEVGEYHSALDILERSENNNVSRIKTEGEAIAVPEIDDTMSIDCSTHLLKGYIYEASDNRALAVESFRAAVQADPLCYEAIHALTQHHMLTVKEEKDLLSSLPLSRTCSEAESAVVLAVYETRTNKYSSPSTPLPQPAAPLATNADFITAQAEKLYYNCNFAQCHRLTQEVLKKDPYHTECLPIHVSCLVELKQSNSLNRDDNIPQLDPPSDIVGTDTNASDITSDITPASADDPLSDSNLLGTSIGQPVMHSSDVGRDSLSQSLAIFQAPVLDIHGPLFQPLGKSPISSMVTLIPVRRYQPLREPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P532</accession>
    <name>A0A3R7P532_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005826</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001749">
        <property type="protein sequence ID" value="ROT75648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7P532"/>
    <dbReference type="OrthoDB" id="1562405at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019441">
        <property type="entry name" value="FMP27/BLTP2/Hobbit_GFWDK_RBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01214">
        <property type="entry name" value="Fmp27_GFWDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit" evidence="4">
        <location>
            <begin position="985"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1396"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1455"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2021"/>
            <end position="2042"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="852"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1792"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1396"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1463"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1499"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2024"/>
            <end position="2033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT75648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2185" mass="248398" checksum="1B8F4E59E5437744" modified="2019-04-10" version="1">MSSTLVFLIILVYYLITRGFPRLLSWLIVAKYQTEIKIGRINLWRLSFEDVLIKKSGLSIKVDRVGATSSLFNQEERKIFALKVHDVRIEKEVCEKRGRAQNEGSNNGSVEAMFAAASTTPEVEAKAIQLRISPSVVTLAQFFGVHIMSVSVVYLRDKWPECLLHGAAEKITIEGATLNQSNIALKVSVSGAHLKVLQHVADEKKQMASVAGGSIVGAGQDPSLMECAISLKLSIEANAETVAAMENISIQLNEPQVTIRERLLTFLENKALAATPVARPTYGSAASATPLDVQLKKYWLFVPLKFQLKVEDIGTKFVNNVGQMALQGTLAGIDLQTHLTREGALENFPALLPDFSTELQVDNIKLHCTHDSSIFLNRFNLQTQFVGDRVNMKSEFRSLHIFYDHKDLGFWTGYMTRRKSQPAMPSYIPDQTNKEKVKPWNGAFHRYCVGLIVEMWDVTCGGCVPGSPYSQLMLQHARHSVFVSQWTTEVEGELLLESMVATLRSGQHSGSQMVASSAAATPRRVHQWGTPMCIGLCLVQLSSVAPQSARSNMSLPPLQAEALLDNIQLEWSPELALLVTAILRYSRELKEYTKNMKPRKVQESDSASSVETFSSMSVKCTNINVFAVTEQKVSLMARVDSLESAKSAKNSRTTITGTKMVRFVPTGTQYLCIKSSEIKGECGQVSEVIVEHVNGELLLNVSEQLHLTWSTTTHMTSFGSGSSCFIRDVILQIQFDDHNIMTLSSGKLSRALQSREVREERESMQELVQKQNKAWRLTVGTWKITFPYNYKFAEAFSDDLLSVVKWIKLVHNRRPKAFTADSPLPPDLVIRVKHWLLEIGDDPFEVKLRYNYELLEDEYQESCKRIKALDARIEELRKTMFLFPTGKIEELYKNLQEKNSETYIKRSKLMYESAPMRTQLFTWTMEDVVIFAMADPTFHGTEKVIQHMVDIDQESPWPQEGQEFSTLWCRMISASCAEWKFKLRDYPQSLLDMSDLEIWGRLIGAEQKASKRAIRNVMVEVGAPWSNTMVERTMSALKFYHDFSCEVKSFTAAYGPCWEPAVAQFNLALSLINQPSRDPSTPLPWWDKMRLLFHGRLTLMVERMTLLLHASLDPYNTTEEMELTWTSLTMDWTNAKLVFKGNLKVSVKTASKYDDARLLHVPNLKLTVKMIWQCRGNPNDHHSVMLCAPDKLPEYSSNQEHDSYRAFRSQNLSMNIQLETKTPKKANTAVSAPVIEALFFGSTLRWFENLKFILSGVARPTRRGPLFNNTHARKPQLSRHYSSIHLSVSFQRFDVRYWMSVGVRKGFHLSGERLSLSSEHKLTLIPVNDGLRHRPRSSWSIVYLNTELCLAQVWLQSAMKDYTTFSDEEDRPQEPVSAPVEKFYFLNVNRVEYTRETLTPTPAESTPDPNLRDKPNHRLVVHGLKGAWTTNNRDIVFALYDSWNKSQQLRRNLTPDIIKSYNPEASTPQKPRSRSITDNSTPQNLTSPTASLQVPPVQATPSPMSRLQSGHAQAMLQQLIAEADNNQVAFSEDCSNTEPRDQIPHGVKACTVDDVIHKKWLIVLVNSQVLLKGCETNGYVILSAANAQILQRIHRPVWQDHSLVTKTTWFGSLECMQYYATVSSAGDKETQMDNIMWLTLDNIEEKDGQVINEVADIVGSGQSVGGVVSQTVGSMDEDDELQLQRIVSRCKCEFYYVAYGETGLDVSLLEEVHPPLPEDDLWSRNVEAVDTFTLVHHDLCASTNSLQYNMVVDILNNLLLYVDPKKKEASEAVARMRFQLQLYSRDDQRKPIIRLQNQVRYHLSQLRSLEKEVYLVQRHLLNDPTNQQKLDEKEVLEKQVAECKEKVNGLSEELAMRIHLYNETQLSANHKWTSSGGDKQTKVIRMNEVSFRKAQWRLTEKDGQLGIADLVLSNFLYTKKTNADDSGEHLLELGYVTMRNLLPNQIYQEVLMPSELQMNMPVDRQRTLRIFCREKPPCGGISIIEHFEVNVVPLNIALTYQFFKTMMKFCFPDNTTEEEFAGSEVSSGGQTTRGSKKQASLRKSHKESNFYVALQDKDDVEIMKQRAEQNKLFVYIKIPELPVRVSYKGKKEKNIEDVSNFRLVVPTLEYHNVTWTWLDFLMAMKQDSKSALLSQAIKHKLNLAHFRADEAATPNEEEKARLLLGSKLMPPESKGTKKSLFKFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5I9</accession>
    <name>A0A3R7P5I9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative choline/ethanolamine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003985">
        <property type="protein sequence ID" value="ROT61805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5I9"/>
    <dbReference type="OrthoDB" id="6378979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681:SF1">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38681">
        <property type="entry name" value="RETROVIRUS-RELATED POL POLYPROTEIN FROM TRANSPOSON 412-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="257" mass="29208" checksum="CC551B9FACCEBEBE" modified="2019-04-10" version="1">MIDRFTRWPEATPIRDITAATVARTFLSTWISRFGTPDTVTTDRGAQFESELWRQLMVLLGSKRIRTTAYHPCANGMVEQLHRHMKQALTSSSSNRRWVDQLPHALLNIRTSFKEDLQCTAAEMVYGTTLALPADFIVTAGNFEPGTFGKQLCERMTRVRSRPTRSTRQQDIYMPPGLQDCSHVFVRKHPRPPLCPPYEGPFPVIRRSDKTITIRRPKGEDTVTVDRVKPAHLHQPTKITKVRFATAKLEGECCSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9R4</accession>
    <name>A0A3R7P9R4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003199">
        <property type="protein sequence ID" value="ROT64747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9R4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="43879" checksum="D32220BFFADE4D0D" modified="2019-04-10" version="1">MTNRALPPGHPSHCRPPVPLPPHPSLCRPPVPLPPHPSLCRPRSVPLPPTRPTAAHPSTAAHPSLCRPHRPSVHCRPRRPTRPHCRPTRPSAAHSHCRPPVPLRPPVPCRHRPLPPTRPMPPTRPLPPTRPSAAHPSRLPPTRPSAAHRPSRHPVAAHPSLDPHPSLGAHPTLPPSAAHPSTPVHCRPPVPPPVLRPPRPTDPSRPGRPVPLPPTRPSAAHPSTAAHTRPSAAHPSHCRPPVPPPSHCAHPSHCRPHAVPCRPPVPPTLPPTRPTAAHAVPLPPTPSLDRPPDPLPPTRPTAAHPSLCRPPVHCRPTPSLCRPPDPPPTRLPVHCRPPVRRPSVTCRPPLTDPRPLHAYSLLSTSILVPEAQSYICSFYNRGGKRENGKRFDCRTHVHLTSESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAE9</accession>
    <name>A0A3R7PAE9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Antilipopolysaccharide factor isoform 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016847</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003122">
        <property type="protein sequence ID" value="ROT65196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAE9"/>
    <dbReference type="OrthoDB" id="6368080at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024509">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038539">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11630">
        <property type="entry name" value="Anti-LPS-SCYG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0044">Antibiotic</keyword>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018754844" evidence="3">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="120" mass="13759" checksum="A2F08E120F120BE1" modified="2019-04-10" version="1">MRVLVSSVVALALIALVPRSQGQGVQDLIPSLVQRIVGLWHSDEVEFMGHSCRYSQRPSFYRWELYFNGRMWCPGWAPFTGRSRTRSPSGAVEHATRDFVQKALQSNLITEDDARIWLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAF2</accession>
    <name>A0A3R7PAF2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001157">
        <property type="protein sequence ID" value="ROT80083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAF2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="659" mass="71990" checksum="E49679F0A97B076C" modified="2019-04-10" version="1">MTLVQFLFLNSFFFLLFSPLFSPPPSSSFLSLHSLLFLITPVFPPFLSPSILPFFSLSSPSPPLRSPPLPTSFSFFFLSFSSPIAPPISFLLSHFLLPNPLFSVPSFLPHSLLLPSLLSSLIPLFLPSFPPILSPSPPLYPSHSPLFPPPSFLFPIPFSPSLLFPFPLHSLLFLPSPLLSSFSLLSRTCSSFPSFPSFIPLTSHYRIPSLSFSILFFPSRFPLFPLIPRCPPCFPSHPLLFLVRLSLPSLSSSLLPVPTPSLPPSFPPILPLSNPLFPPIPSFPPSFPPIPSLPPSFPPIPSFPPSFLPSLFRLPPFPSFPSFPPIPSFLPPFPSIPSFSLPIPLYSSLLPSHPLCSSSSSLPIPPPSLSFSHSLLSPSFPSIPSLPPSFTSHPSLSSLLSRPSRRPCLPMPCEPSSSPRFTLIPILLFPPSSGIPFFILPIPLNPSFPYPCLYPNHPSPRSNISLPPSPFPLSPSCFFLLFSLIPICPSSPLLLVFLIPFHPLSPIFPSFPIPLIVIPFPFSPPSSILVIRLSFPYFPLPSPSLPFTHPPPLLSPSFLSPPSPPLPLSHSLFPFSLPYTCLPSPLSLILFPFSHPSFPSPSLPLSLILFPFLRPIAPLSLSPSPSPSPFLFTLSSDHTPPSLLNITTGTQDPLTSQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBT3</accession>
    <name>A0A3R7PBT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Polycomb protein SCMH1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000026</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001002">
        <property type="protein sequence ID" value="ROT81200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBT3"/>
    <dbReference type="STRING" id="6689.A0A3R7PBT3"/>
    <dbReference type="OrthoDB" id="5912862at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20092">
        <property type="entry name" value="MBT_dScm-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000016">
        <property type="entry name" value="polycomb protein SCMH1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004092">
        <property type="entry name" value="Mbt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050548">
        <property type="entry name" value="PcG_chromatin_remod_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010507">
        <property type="entry name" value="Znf_MYM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12247:SF132">
        <property type="entry name" value="POLYCOMB PROTEIN SCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02820">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06467">
        <property type="entry name" value="zf-FCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00561">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51079">
        <property type="entry name" value="MBT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TRASH" evidence="10">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="10">
        <location>
            <begin position="59"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="MBT" evidence="8">
        <location>
            <begin position="169"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="MBT" evidence="8">
        <location>
            <begin position="276"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="399"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT81200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="480" mass="52198" checksum="93C0C0002BB663AE" modified="2019-04-10" version="1">MPTPGRGPGRPPKNPRTCTWCSEVKSQLKYVFPTSSGKREFCSETCLSEYRKALRKGTCANCDNVIRSTPVKCETSSGRRRELCSNECLKAWAKKEKDKEQQPDTEEEAGVASSSFSSMTSPPSSMSPSSGNGVSPNEKASLGPEAAAGRKGRGLSAAALAQIEAAAEFNWEDYLRETNSIPSPAKCFKQHKIPPKNEFKIGMKLEALDPRNLTSTCIATVVGTLGPRLRLRLDGSDNKNDFWRLVDCNNEIHPIGHCEEHGGMLQPPLGFRMNASSWPMFLLKTLQNAEVSPPHIFRTEPPTPAKNYFEVGMKLEAVDKKNPQLICAATVGAVNGDMIHVTFDGWRGAFDYWCRYDSRDIFPVGWCAMSGHPLQPPGQMWGPPSSRYKARVLNIPPPLAGSSKSPEVPSATAASDKSPSSAASSPLAKSGGRGRHHSPTTPGSPPLPATVHTHQGGLASELILIDKVIYVHLRQIILVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE87</accession>
    <name>A0A3R7PE87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_019250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003530">
        <property type="protein sequence ID" value="ROT62882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE87"/>
    <dbReference type="OrthoDB" id="6413868at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.160">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT62882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="175" mass="19763" checksum="BA09F222868DB7DC" modified="2019-04-10" version="1">MSEGKEDLHYHFYPHNQHLFNLPECATQQVCNAVYKRLNFTQPLCACPSGSDPCSASFRADDRRSIELRMGGPQSQAVTLIKTCEPIWSVRECKSPRDWSILALQNTRTGKAHYLVICKCPDSARLDGPLNHDQPAYAQVPGIRVYGMMCIRSSFRRAGRVARDSRRESFGVTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF10</accession>
    <name>A0A3R7PF10_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PBZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012499</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HPF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002583">
        <property type="protein sequence ID" value="ROT69305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF10"/>
    <dbReference type="STRING" id="6689.A0A3R7PF10"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072572">
        <property type="term" value="F:poly-ADP-D-ribose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019406">
        <property type="entry name" value="APLF_PBZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019361">
        <property type="entry name" value="HPF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13386">
        <property type="entry name" value="HISTONE PARYLATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13386:SF1">
        <property type="entry name" value="HISTONE PARYLATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10228">
        <property type="entry name" value="HPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10283">
        <property type="entry name" value="zf-CCHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBZ-type" evidence="7">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="47858" checksum="05FFBE21F1F2AF65" modified="2019-04-10" version="1">MSDPETEYQDDPRTACKYGESCYQKNPQHHNRFKHPPKRKLEYTESEAEDLVPKGKKCKTEDNEENDSDSGDNFEVPSIDKDDDKADTSQPEEDAAESPVHELEVAASPENVRESIEQKFLLDMPDDFFDLWDLCKTLNKEKPEEAFIKAGITLVGPYDILSGKLKNLKTRKISSYVCHWRYYYDPPEFMTVIAGSEDEYHIGYYRDDCFLLPAFVGSMSSVKPGSITLMGGNIFSAVSIYLSQRMKAENPFKKITLQRLQQEVDNFAKLKKHSLEQRPSSVQERSKKVVSKCFHGAGIVVPVHNDVGYRPIPETNACLKKIFQKVVDAKSEEERLKHFDAVQELMTNVQFAFDEGDFGMGLEFGHNMFTFGGEVFHKAISHILGVAYELLGRDAFVDILQAHLKNRRRGSNLSILEVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFE1</accession>
    <name>A0A3R7PFE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011898</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002507">
        <property type="protein sequence ID" value="ROT69882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFE1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="414" mass="44913" checksum="B71AD98D273F2881" modified="2019-04-10" version="1">MPVSPLPLPSSSCPLPLPSSSCPLNSSLPALVLLPPLPPSPLTSLLPYPHTSSLPALFPYSPLFPPLTLPFLPIPPNHTPRPPTAARNHPFRLPPSTLSPPPLLPPPSVAVNVSEIIFLIKQSPKVTLGPRLLPADISSFELVPPSARFPLHFLLSLTFVAFQVSLVYQQSKSSPLAALLHPSFLPFLLFLPSSLPSLSPPPSLPVPFSLPPRLPSLSPFPRHPSPSLPPRLPSLSYPHPSTPPLPFSSLFSFYIPSPVLALHTPRPCPSLQHSAPASFLEPPLSDPLPSPPVSPPHSLPSRARPSDVKRFLYQSRTPMRYKRRQQRLFLGRDTELLIGTKPARASTRSSLWLFRLDVSPGTTASQRRRPRGLGARCQDGRRSGKARRAPSKSLKGRSSGRNTPSDAQLAAISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PFY4</accession>
    <name>A0A3R7PFY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0729 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002412">
        <property type="protein sequence ID" value="ROT70531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PFY4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026776">
        <property type="entry name" value="UPF0729_C18orf32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13456">
        <property type="entry name" value="UPF0729 PROTEIN C18ORF32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13456:SF0">
        <property type="entry name" value="UPF0729 PROTEIN C18ORF32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14975">
        <property type="entry name" value="DUF4512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="50"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="103" mass="11108" checksum="EC060FF0FC86E54B" modified="2019-04-10" version="1">MLGMYYWQNPTAAAAMVCIPCIVVPVLLFIWHRFLQPIFLKLWNPWGKVTDGTDKKTDDKDGKSACPASNGTATANGSLSCPFSGKAATPADGQSEEGDKKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGK2</accession>
    <name>A0A3R7PGK2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003026">
        <property type="protein sequence ID" value="ROT65855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGK2"/>
    <dbReference type="OrthoDB" id="6387277at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018573158" evidence="2">
        <location>
            <begin position="17"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="50385" checksum="A40B599EF3870333" modified="2019-04-10" version="1">MKVALLLLAGLACAGAASLPALALRPPSPSHQLVPGAGPVKQLRPALRPAHRSARLSGQAAPRTILDTILSILHSLGVSDEEIAAALDELQHQMEIVIADMTPDEILEVQHALDDILNQVNSGEADINQIVQIIFDIIAGAAGGKEAQPKTILDTLLAILTLGFTDEDIAHALEELQHQMEIVIADMTPDEILEVQHALDDILNQVNSGEADINQGQLPSNRSSRSSSTSSPEPREARRLSQDHPGHPPRHPPRLGFTDEDIAHALEELQHQMEIVIADMTPDEILEVQHALDDILNQVNSGEADINQVLVDLSIIYTDIYPHLTPEGQAALEQIVQIIFDIIAGAAGGKEAQPKTILDTLLAILHALGFTDEDIAHALEELQHQMEIVIADMTPDEILEVQHALDDILNQVNSGEADINQVLVDLSIIYTDIYPHLTPEAQAALDQIAQIIIDIISGGLGSKIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHH0</accession>
    <name>A0A3R7PHH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002913">
        <property type="protein sequence ID" value="ROT66652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHH0"/>
    <dbReference type="OrthoDB" id="6368911at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="403" mass="43751" checksum="5B0C0686C829C9B3" modified="2019-04-10" version="1">MPHFKIKLEDAVRAVSQAIATVLKYSSNATFISTCLSRLQASSPAEAEHRVALHLWSILHRHQGASIPLEIAHELTMVPLCQDQLSVRLFTCRDDDAATEERQGSGQGNDSPADLFMDDGRDDLLFKLATSDLRMHSAGGTTAAHVAPQSQASPGASALNAQDAHTPVSPPLLQSHRPRGNGEQSLLSDDVLIVEQADKEGAAGPPSPDEDKEEILRGGIAHDSQDLLQDVSALGSSWGSLSARVLCDPTPSEPSLQFSRLDCLEESQLMADFSPEEEEDFTAADGCDLEPYCQSDSKERIDQALFLLSQTPTPSAQEEAYANTKRLMERALADLSECMAEDDPAARKNPWWCPLPSQQVEPQPPLPDMGNSSISLNTTKESESVSILRDLDKTKPSGCYRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PI67</accession>
    <name>A0A3R7PI67_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative aminopeptidase N-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014562</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002818">
        <property type="protein sequence ID" value="ROT67360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PI67"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3480.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF294">
        <property type="entry name" value="THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="3">
        <location>
            <begin position="111"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="304" mass="34035" checksum="D6E71C5CE986CC1C" modified="2019-04-10" version="1">MYFFLTEATFKKGLTNYLNNFAYDAAAQDDLWQFLTEAAHEDDTLPSDVSVKDVMDTWTLLTGYPVVKVERNATGTAATDAPDFTRTRPSAWLTPGTSTLILDGLPSADAWVLLNLQQTGYFRVNYDAGNWELLTKQLADAHEVIHVTNRAQVMDDALNLARAGQTYLLDLITPLYDDVGFEDDLNGLHLDQYKRVLALSWACHLGHPQCVAESAQQFGEMPRLSEPEVDGLLLSHRGRRSVRSVGDGVGVVPRGQRTLEWAFTEGSGIRRQDARTVFRAVANNDVGRYIAWDFLRNRWGNHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIT0</accession>
    <name>A0A3R7PIT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002737">
        <property type="protein sequence ID" value="ROT67913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIT0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="567"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="658" mass="71018" checksum="2BF315739915CD5A" modified="2019-04-10" version="1">MFASSSLLSFPSSLPSYQVPIVILPTSSASLFSSVLFFFLLPKRHTPSPLPTVPPLSFTLLFLFFSSLPLPPFSLLFLLIPLILFSLSHILSSLPLLSLVPFFFSPPLIFSSLSSLLFISLSSSLSLSLSLSLSSLFPPSRPPLIPLIPLIPSFLSLSFSPSPPSSLPFSSLSPLSLPPSSLLPSLFPSLSPSLPPSLPPLPPFTPLSSLSLPLHPSLPSSSLPCPLSLPSPLLNTPQISSLFFLSPLFPLISSSLTFLISPPLPHTRLPFFFSPSSHLSSLFLSLPSTFLLIFFPLLLLLFLPSSLLSSFLPCICTFSSLSSSCPPFFCLCSSSFSPPSPSSPSLSLFVLFSLRHFPSFYFLLLFLILFLIPSHLVPFLPPLSSCSFPPLPCLPFLPSSPFIVSFLPLLFFLFLHISLFPFLPFLFFSPPPLSSCSLPSSSSSFFIPLSSSSPPPLPLLVPSPPPPPFLLLFSPSSFSPPFPPPPLLFSSLFFPSSSSFSADRRLHCVFSILPLPSPPTPSPLYPHPHLHSSPLPPLHSPPPLPLPSPLLLPLSITTSPQPPHPSHTPSSSLHCPYPSVFPTNPPPSPFPPLSPPPTILPLPSPSLPFPPSPFPLLSHLPPPSHVTPLPSRKYQNSSSQPFLNLPPRTQSRVFVSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUS3</accession>
    <name>A0A3R7PUS3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023644</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000722">
        <property type="protein sequence ID" value="ROT83184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUS3"/>
    <dbReference type="STRING" id="6689.A0A3R7PUS3"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000008">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 14" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="15">
        <location>
            <begin position="147"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="226" mass="24363" checksum="1FC57452E7A87FD5" modified="2019-04-10" version="1">MAVESSLPSSCRASMYLAGMTGSRPLAPATCTGHNLLQETSLKFLVAAAPGPPESPAGSCGRAAGERLRLRGSRSAKMASLSRTLRFAALIRPSAVLSVVPRAATVGCLHTLTSRESRLSNTTLLSAITKATSGVRSYSAKEPLTLDLIQQRVMLVLKLYDKVNPDKLAVDSHFMQDLGLDSLDHVEVIMAMEDEFGFEIPDGDAEKLLRPADIIRYVADKEDIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVJ0</accession>
    <name>A0A3R7PVJ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000629">
        <property type="protein sequence ID" value="ROT83887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="467" mass="50337" checksum="C5F3DAF6C186E03C" modified="2019-04-10" version="1">MTHNSPSPYLIRRDFLPLVSPIPLLHPQYHPPTTHRPTPIPSLPLPYPSTPSSTHPLPPTTPPTHLLPTSLPTTPLDHTHPYPPPTPLPHTSNKAAPSTHIRPRGRGEARGGRGGHRQLLGRRAVDGRGLSGVGRGGRRGVRXSPSLFSFSPLPFSYLFPLSFPFLPSLPSPLPPFASFSPLPPPSLPIPLPLPPPSSFFLFSLSSFLPFPSLSLSLPSSFSSFLSLPLPLSLSSLPLLFLPFPSLPFSSSPPFSSSSPPSSPLSLPSSFPPFSFSLPFLPFPFPSSSLPSPPFSSPLLFLPFPPFPSPFPSLSLLIFPLLLPLLFLPFPSLPFSSLLLPPPLPSLLPSLSLLLLPSPLLLPSLPPPPLPPSSSPAKPPALNVNKGCFPPHFGISKGENKKEKKISFSFPFLSHLSLPPSSSLLISPSFLFIFFPLLPLPFLPPKPPKEGLFPLKKKVFEKSRSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q023</accession>
    <name>A0A3R7Q023_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000817">
        <property type="protein sequence ID" value="ROT82495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q023"/>
    <dbReference type="OrthoDB" id="6358661at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="535" mass="58629" checksum="6F92FC97DBA02F96" modified="2019-04-10" version="1">MSNQNSRSWIIHLSRQFLKSINPPPVINRRLLHAPWDPEAHAQGGREGVDTFTLAVYMSAGGRAQPQTESLPRPAMIIHRILLLALVASAAWAHPQRQRQSPLSMGMRFLGNIRDGVTKTFQGIFGGGNTRQTKEQIQGRPFQQQLAPRPHPGPVQPHGAHEVVHHSSSHTTGPPSSFFTVVHEAPEASTAFPDIQGFTDESFKPSTFFNGHTPFQGKVEEEELPLVVNEVVVSRPETNVFARPPSFLVTHDPQADKHVPPSHNSQTSTFSSFGKSPLDTPIPFGNSATFSLGKLRDSSSDPPSPFRDADEDTDALGPSSHTSGHGPRPTPFVQRLKPSVGSPARVEPTTHPFVHRPHPTTRQFLQQTRPTSRPHSSLKTKPSSTFFKASNPFKASEEITKAPKHSFTSSIPAEPSSVAFKPIAPSPSPSPTLFRHTPSDVVRHAAPAHEVRPQREAFKKPVTPAKVGGGHINTGTKMTVVSTLNEDGTQIVTTRPFLATCMMRGRKFRPKPKRENEQDRDTNPQTSSDVTCIVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q273</accession>
    <name>A0A3R7Q273_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">JHE-like carboxylesterase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_015352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-B carboxylesterase/lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q273"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019819">
        <property type="entry name" value="Carboxylesterase_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050309">
        <property type="entry name" value="Type-B_Carboxylest/Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11559">
        <property type="entry name" value="CARBOXYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00941">
        <property type="entry name" value="CARBOXYLESTERASE_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0719">Serine esterase</keyword>
    <feature type="domain" description="Carboxylesterase type B" evidence="6">
        <location>
            <begin position="180"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="451"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="609"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="706"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="616"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="719"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT66553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="763" mass="84852" checksum="44CB45C6CD40FB52" modified="2019-04-10" version="1">MQHHSPLQCLSSSACLPGFYPPASLLLFPSTLSHARTFTPYPSPLLLLLLAPAPLLLPLPLHSLYSPPPLLPLLPHSLPSFDLLSTPISTLCDPTTHPLFLFPLPLCCLYPPLPSIFLLLPLFPPLPLRLSPPPLSFPALTLSLEQREDDTSRYHWKPLQNGDPVRPRGFGSAVSRCQRAPVVSLPDGRVSGVNERSAKGRDFFAYYGIPYAKPPLDKLKLKDPVRADKWVGTRDGSKMPPPCVQVPVDHVLLGLPITLDDIVGEEDCLYLNVFTPKKKKPDEKLPVMVYIHGGAFFVGGAHEYLPHVLMNHDIVLVVIQYRLGTLGFMSTEDMVMPGNFGMKDQVMALRWVQENIHSFGGDADRVTIFGESAGGASVHLHVLSPMSKVGEKFRQGAFLTSRVVRCPKCILTKDVTFCMQLTDGKEVASAVKNFTEWFIFPVRMVRVTATSSPTSQRPSCGEGSTTASTSWPESRGRRGDALFSGESMVRALEENFTHFGPVSLGFQDEEDPVALATRVYKHYLGDIVFDEQHSDQLTRAYSDVHFNLPHDLTSQIFARDPGTKIYRYELKHRSQLSFGDIYDMSLGKNWITHADDLYYLFRGGPLFAPDSPPDRPGTSRTRTTSGSGTSSPPCALCPSFAPTQEAQTEALNPSLSARRNPTPDDSLGFTWEAATESNFRHLALKPSPEMMEDDQRQEIRRFLTSLPPESTGCSAPTASRRRRTTRRREPRRTSCDVIGRVTVGGYFHSDFLDREFLDRLVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q6R0</accession>
    <name>A0A3R7Q6R0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Synembryn-A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_011802</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cell cortex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synembryn family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002489">
        <property type="protein sequence ID" value="ROT69964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q6R0"/>
    <dbReference type="STRING" id="6689.A0A3R7Q6R0"/>
    <dbReference type="OrthoDB" id="5585685at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001965">
        <property type="term" value="F:G-protein alpha-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008376">
        <property type="entry name" value="Chaperone_Ric-8_A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019318">
        <property type="entry name" value="Gua_nucleotide_exch_fac_Ric8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12425">
        <property type="entry name" value="SYNEMBRYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12425:SF5">
        <property type="entry name" value="SYNEMBRYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10165">
        <property type="entry name" value="Ric8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01802">
        <property type="entry name" value="SYNEMBRYN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="558"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="64092" checksum="7B91D215593D6CBA" modified="2019-04-10" version="1" fragment="single">YEQQFTPVGLSQQCTERLWNVIMGRLSDPAASVTHQTCLSVIRILSRDKQSLNNVIDSDRLAVIVRLAGLVPEEEALQRLNQQINYDVVTEAQKCLSNLLYNSSAIQRMCCVNSCIPGLMCRLKTFKDPDLPHLVKYFDMRLLFLLTAFCGDIRPRLRSEYHGLTYLIEILDLSLKTAQEESEVQSINGYLPNPIIFNDEQAELVNEVLKVLYNLVLHIDKNSPDEEEDSHCLRLISILRYLLLASTRCPEKTDSLHSNTVNLLLVMPPKMYEELLCDMPQASESPMPPPAPTVVTTQPTAGATALMEAACFTEVDSDLSKQNERSCEYDGKDMTAIIKLLDFLDSRLKSPGQSSSKSLMPILTLMVEMTQANRTIRKFIRLRILPPLRDVSKRPEEGHTIRNKLCSLMTSPLHDLKHLSANFLFILCKESVDRLIKYTGYGNAAGLLASRGLMLGGSKPTIDYSSDSEDSDTEEYERVKDMINPVTGRYEPPRPSPLDGMTDEQKEHEAMKLVNVLDKLTRNNIIQPCRIGDDGKPHPVESVMELQEGLGVLPTGDHNNDSDDHNNDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q8L3</accession>
    <name>A0A3R7Q8L3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010322</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002305">
        <property type="protein sequence ID" value="ROT71350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q8L3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="43653" checksum="56A9BDD254E5DA2A" modified="2019-04-10" version="1">MALGTNVERSRTVTQEKKRTIQERREDLSKIPVSVQAWIAYESRGGLTVDRKGMQRNMRLVMEILETHSLTIMDLIEYYTVETSYELLYKTLENRKYKYASIGVILGHLKRFIDWACTETNRPLCELTNREHNFYIKLCRKKGNVENMNRKAAEYVPTIDEMGPLIQYTKHRDIMDGLIDQPRETLYEYGADLVHATLAWPLIIRAGARTGVIKNLLTDEVVNAVKSSDGVVISVKTHKTSLQYGPYQIGIPAREHDALVNFINGRDWESKYVFSSRRGAPFSMANIQRFMRKLFLLYDLPRLRIATVRKFLTTQAHREGDDRIQEATASLLKHSMKTAKRDYKAMQRDHDALDTANRLSKMLREKLSEKVTVVMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9B9</accession>
    <name>A0A3R7Q9B9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dCTP pyrophosphatase 1</fullName>
            <ecNumber evidence="1">3.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dCTP + H2O = dCMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22636"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="EC" id="3.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.12" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002241">
        <property type="protein sequence ID" value="ROT71822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9B9"/>
    <dbReference type="STRING" id="6689.A0A3R7Q9B9"/>
    <dbReference type="OrthoDB" id="411123at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047840">
        <property type="term" value="F:dCTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006253">
        <property type="term" value="P:dCTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11537">
        <property type="entry name" value="NTP-PPase_RS21-C6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052555">
        <property type="entry name" value="dCTP_Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025984">
        <property type="entry name" value="DCTPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46523">
        <property type="entry name" value="DCTP PYROPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46523:SF1">
        <property type="entry name" value="DCTP PYROPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12643">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR029826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="18125" checksum="9A05A2FF26E58D97" modified="2019-04-10" version="1">MAQSDPEDREFKFSSNLSLEEIRSDQHNFCKERNWAQFHPPRNVLLALVGEVGELSELFQWRGEVTRGLPDFSAHEKTRVGEELSDILIYLVDLAEQCEIDLPRAVKEKMVKNAEKYPVERVIGRSDKYNDYPEYLLQEAPAGEEPQPEREEGDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBC4</accession>
    <name>A0A3R7QBC4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003680">
        <property type="protein sequence ID" value="ROT62444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBC4"/>
    <dbReference type="STRING" id="6689.A0A3R7QBC4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="554" mass="59743" checksum="1327A2DE491A534B" modified="2019-04-10" version="1">MIFLTREFPLATSIDFVINCTWTSFGPNAWSGEQLGKEAKGKEALSSNGVWPDAFRCASKEVLVVLNLVSVVSDRLAIDGRGDPETAETDQINANTPILSEGARVTGALSVKRDGNIWPGTNDKAKCETVSVHLLISPRRRFNNTGRAMFRSPALLTPTLPSHSFPPSLTPSFPSLHSSPPLSLPPRPYPPFLRPPFYLSASLSKLLFFPHSLPSPLPPPSPPNPDTLLLSLFPLLPSFSPSLSLLLSFLFLFLSRLSSFPVFLPSFILSLSRPCPSSLFLSLLCPLPPSSSPSPFTPPFSPLHSQSRSAPFFCLPKHRFNPSSLPPPSPCRYPFPSHSFPSPFYPFSLSTPPSPHPSNSLPFASSPPPPLSLSLSLSQPHPTPSPFEALPMSPTPLISLFFLFSLSPSPSDPSPSPLSQALPLPFLLPFHPLSIPHPHLLSLPPSPFEPLPCPLPPPTLFLRPPPLLPSNPSPSPPSPTPTNPSFSPPPPPPPPGHPGPGIMTGATCPEAISILMKSEKPGEVPRQTRWTERLPVLEPREASLARDGRGLLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QBF8</accession>
    <name>A0A3R7QBF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003652">
        <property type="protein sequence ID" value="ROT62513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QBF8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="699"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="729"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="781" mass="85151" checksum="561BBD6B247A9464" modified="2019-04-10" version="1">MDWREDSDRISDFRERERGFSSLSRSPLVPLSRSLSRSTLLVPSSRSLSRSLLFPLSFPLVRSLSFPVSFPLSPCLFPSLVPVSFPLLSSKCLFPSLVPCLFPSLFPVLPSVSSLLSFLLFPVFFPSLFFPLSFPVSFPLSFPWSPLSLSLSRSLLFLSRSLSLSLSRSLSLPSLFPVSSLSVPFSFLSRSLLCLFPLSFPCLFPLSFPVSFPLPFPVSFPLSFPVSPTLFLVSPVVPCSLSTFPGLFPSLCLTPISEIPVLLSFPSFSIHRSLSLSLSLYLHPCLFSYTSLYLVSLILFIPFSSRSLSNFPLSSCLFPLSFPVSSVSFPVSSLSPLSRSLSLSLSLVPCLFPSLVSSCLFPLSFPVSFPGSPSLSLLSRSPVSFPLSSFPVLSLSFVSCLFPSALFLPLFPLFPFSRSPVLFPSLVPCLFPSLVPCSLSLSRVLPGPFPLSFTCLLSPLCVVSSSFPLLVPSPCAPSPRPLSLFFVPCLFPCLLFPLSSVSFPLSFPVSFPSLVSLLFSLLVPCPFPLSFPVFSLSFGSLSRRLPLSLPWSFPLSFPVGSLSLSLSRSLSLSLSRSLSLSPHLPCLFPSLVPCLFSLSRSRLFPLSRSLSLSLSRSLSLSLSRSLVPFLSRSLSLSLSRSLFPSSLSLSFPLSLPPRSLSPFLSSFPVSFPLLFPLRSVPCLFSSLFPRLFLFRRSPLSFPLSFPSLFPLFVCPPSSFFRLLFPSPSLVFPVLFPFSLSLALVSCLFPSLVLPVSSPRSPTLTSTPLFPSLVPSVSGLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHQ8</accession>
    <name>A0A3R7QHQ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Variant Ionotropic Glutamate Receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_001981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001261">
        <property type="protein sequence ID" value="ROT79301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHQ8"/>
    <dbReference type="OrthoDB" id="6377023at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018654629" evidence="10">
        <location>
            <begin position="22"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="609"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="11">
        <location>
            <begin position="369"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="632" mass="69978" checksum="CB22857B84034155" modified="2019-04-10" version="1">MGIHIATGILWLCALVPKSSARLPLETSIGEAAYSALQAINAVLNPETRDFCSLLLFRDPLTASDISLDLKLLSEQWSVREFEVETDSENATLDISWLIAEARKVRNSSYCTRVVVLSDDPAFLASFAESSLRGRLLVWATRLLVVTRLPLQELRRLLASSWTFSMMNAMALRIEDAFSSGVYSYLPYSPSGARVVRVATWSSSRGLTIAGHRQLFPQKFSNFHGATVNITALPYRPYWIEKTKVAPNGTAVTTYTGSDALMMHAMAQALNFTFHVLPSKDWNEVGFQDETMLTVMLSLVEILVMTKVVVVTKKVAERESFIASVVHLHLPQRQKIYDFTYNYEITNSDFTLAKPSLRPSWQGLYYPLSNEVWLCILFVLLLTPFLATLVICNRESEGDVKTMSLKLIGSLLGQSMASGRGESGGSRVFVASWLVFAFVVGTAYRGNLTAALTLPKYPPRIETVAQLAETVDRLLAPPYGKDVRDFLTQSESKIFQVFGSKLELVPDILSGLKQASNRISYIESDRFVRLAIVEHFTLADGSNSLYVGREKFLTSIAGLPVPHDAPYKPQIDRFLMMVIERRSETAAEETEATEGNAKALSVTHMQGPLLLLLLGLMAAGLAFLAEVLAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QIP1</accession>
    <name>A0A3R7QIP1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thrombospondin II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_013140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002644">
        <property type="protein sequence ID" value="ROT68698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QIP1"/>
    <dbReference type="STRING" id="6689.A0A3R7QIP1"/>
    <dbReference type="OrthoDB" id="6357843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 3" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018575335" evidence="4">
        <location>
            <begin position="18"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="6">
        <location>
            <begin position="199"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="332"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT68698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="44541" checksum="8CDA70C799F84A55" modified="2019-04-10" version="1">MMSFMIILGMVAATAVAMPTNVPDCSGEGRFPNPNTCGGFYDCIQDDNGGYELSFDDCNGFVFNTTSRTCSSEMCLSRSERSVTNAYPRYSYLCEGQPDDFVCADCRTMVMCVKGQAFARQCISGRSCSIKAAFGGAVCYPGHPAACTCQSADSFVRDLYDPQKFFSCSGIGVLPEIHVCPDGMVFDETLVQCRNQASLPACRRPGVFANLDDCSEYYSCISLQSGWLQRLFMCPNGTLFNEATGACEDPCKRTMVCYEEGRFPDPLDRRSYYECLIIGGLMKRARYQCPHGYVWKANDSGDGGACVEDHEMNLYDYFTRCSIPQGMCPDETTDPCLANNGGCNANADCLTINGGVSCTCRAGYSGDGYTCIDVDECAVANGGCSASATCTNSDGSLQFPVVQLLSRIHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QK35</accession>
    <name>A0A3R7QK35_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_025427</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000976">
        <property type="protein sequence ID" value="ROT81425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6356419at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009039">
        <property type="entry name" value="EAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15261">
        <property type="entry name" value="THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15261:SF4">
        <property type="entry name" value="THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50912">
        <property type="entry name" value="EAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT81425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2028" mass="219627" checksum="6FD0824E0943FB9A" modified="2019-04-10" version="1">MVQVNGKTSSLTACSLGHSSASELTSAVGGNPTRELAGDINSDPDTAEISDEQESGVLGRLWSSLSNLTGLKKRDTGERLERFRRELLTSWHHNIKTVTHASKRYRRGLEDGLVTDTEGYWLLTNLDDNVSPRLKSLNAPTGTNSMTIFEHDSRLFLVATHGTGIVVYSLNLTTVTPQGTYTNYDKIDAASFITKNARGLVAFKIMTNQFVAVANHMDNKGNVEVDSEIFIYDHYYTRMRPFQRIRTSAARDWAAFHFSNGKKTEYFLAVANEFSFDAAGRKNYNIDSIIYRYDEASEKFLPFQCIPTQGAYQWITYKGPHGEVLLGVVNSASGVAFYQYNGWRFVRINIPVSAPGVEWAWIGKLPNTLNEVLFMMSSSQANPRPASSYLEFTYQNPLGTYHNATAEWCSAYKTEMTNDGLSQLVLDMEQAPKTNESHTFTKPVHIDGSLTLPAGSAVSEVRDILCESESTAVDYKFHIDTKTLIDDRKDLETKLGGVQNTVSQSISINSPNLDGLHFAHLVTTCNTPGCIASTVDSLTANTVNGVSASYTGIALLNNTNEKLDLTFADVALAGGAVCSVTNIKAHDTAVIPMNELVTLHQDHTITADVTFNKVLADNMQVSGTVDGLTVDDSTLLLTYGTQTVNGLVTVDGVDTTLITTTNVNSRNFNDFIDSLIVNGTTDSFQGLLEVGDDLIAPNIDTLEDMKPLNPVDVEARALFHTKTSTQVVTGLHSVGNLEAVNGVWFDHLNGVLVPDDVFLKDETVTVSAPTTFDSITATSIQVTNAMNDVKQVGGSLEFLLLDKDATLTSKTFTDLTLEKDSTVAKLVAGYDLDYLAKGLHEKFLQDLNSGRAVNGSVIFEKELHVTSDKIHGVSIGKIRDTAIPLTATSLNPALTFEKPVPIAGAMTVSSTINGVAKDDYVLLDSDHTIVSPKTFVSDMECREDVTAGLVSGYNLAKFAKDVVLKKGPAQIIVQDLSMASADVNGDLNVAGQITIGGVNFNNVVALNATETVRGKKTFTNVEVTSSTSAGAVNVGDFGTVDGVVVKEIFFDDSLRKSVTSTQELVGRAMDTIIAQNAEGTDLAGFERKVVYKDDIETISGALTLEGSVSIASLNFESDFDGVSEAAYKSAWLLNEGPQTLTGSNSLANVDASAVNFQGIYVDGVHLGRLHTVTAKIDEQTTLNSTTFDQVESLSGITLDGTIQGWHLHEQALQSSSNHQRVTGKKRFTNPVHIKNSITVDENVIIPRAGGSPLVLEMSQFCDAFMQNGKVLGDLVVNGNAVFNKDLDISKSFNNEDVSTLASVFWLSDMDNTVSSVKQLDTAQVAGNAEVIMKGLINGEDFSTLASDVLKNKCTSQSVTASWNLDNLEVSSLQTDTVTNTLLDSDVFDLERILRTDKTQTITGAKTFPEVQVAGSVDLDGTLNGLDVKTNLVQYGKGADITAPKTFNQKLTVKGDLSMSSGTTVQGVDVSAFEESAVLHNTSGITKSIGGITTFKGLVLKTLEVGGTVDTVQVDSNTILLTSGAQSVAGLVTVSVPGQDKVVFVDQNLEVQDQMFNTIKLDKLYGDTVRVDGSKDTITAEVTFTASPTFSSITLENHLVNGYNLTDLILFLDGKHTLDNMGDHLEEAIQSSQDSNMVLEERPTDLWYFYETKLQETLYKLQPITLASPLGHRSIDAFVGLNWEDTSIQIYGPELGRKSLADELKDICEEKEHLDVLAAFPPTSTISIPKAKVAAGLGNNHLAACGDSLVTFPYAAAPTYQQISDELGQGTSYGHVFSLNNPVQTVVSFSTVSCKDLVPFHLENGKDCLAVIDHGTTSEVICGTAQTGYRLLNYLGTKHAVKGAAFTLGNEYLVVLEDDSFSFSSNLKTFKYDLHSNTMVLELNHDLQKASHLDALAGNHKAYVAVTHSISPVAAGGVDIFTVTDKSGSVEMKKMQTIKVPGALASNFGELAKYDVGLFVQTEHGVHVYVLKGMQFVHERMVKTVPARKPFSFPFFHTGQNTTFLLYAGNDLDGHLERNARVYEAVYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKM3</accession>
    <name>A0A3R7QKM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002425">
        <property type="protein sequence ID" value="ROT70437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKM3"/>
    <dbReference type="STRING" id="6689.A0A3R7QKM3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="630"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="801" mass="92832" checksum="D70B10971672E6FC" modified="2019-04-10" version="1">MSSGKSQEKEEPRSKRKSLQREEPRSKRERVRGSKGEGRAEVKEGRAEVKEGRAEVKEEERGQRRKSPRVNEGRAEVKEEEPRSKREERGQRRKSRGQEGRPSQRGKSRGQEGRAEVKRKSRGQEGKAESKEEERGQRGRAEAKREEPRSRAEVQEPRSKKEEAEVKGKSRGQRGKSRGQRGKSRGQRGKSRGQRRKSRVKERKSRGQRGKSRAEEPRSQRGRAERSKKEERGQRRKSRVKEGRAEEVKRGKEAEVKEGEPRSKEKSEVNEEEPRSKRKSPSQRKRGVKRGRTRSKRKSESKKGRAESTREKVQRVKRKSRGRKERAGQRGKSRGQRRKSRGQRRKSRGQRGKSRGQRGKSRGQRGKSEVKEVEEPEVKEEEPSLMGFSCHARARRNGGRFAFCLPLLSSGVSRSAGQRRKSRGQRSEGRGTRGRAEGSKRKSRGVKEERKREEPRSKEEEVRGEEARSKREEPSQRGKSRGQRGKSRGQRRKSRGQRGKRSQRGEEPRSKKEEPRSTRKREPEVKGGRGRGQEGRAEVKEGRAEVHRGRARSKEGRADRSKKEKPRSKKEEPRFKRGKSRGQRRKSRGGQRGKSPQVQRGKPRSKGKSRAKEEPREVRAESKKEEPRSKRGKPRPRRSKKGRSRGGQMREEPRTSREGNEPRSKGAGRAEARSKKEEPRSKKEEPRSKKEEPRSKKEEPRSKKEEPRVKAEEEPRSKRTEEPQEVKEGRATSQRRKSRQRGKSRGQKEGRAEVQRGKSRGQRGKSQRQEQERKSRGQRGKSEVKEGRAEVKRGRPRVKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKX3</accession>
    <name>A0A3R7QKX3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cryptochrome-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_024692</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000878">
        <property type="protein sequence ID" value="ROT82146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKX3"/>
    <dbReference type="STRING" id="6689.A0A3R7QKX3"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF17">
        <property type="entry name" value="CRYPTOCHROME-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0274">FAD</keyword>
    <keyword evidence="11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="12">
        <location>
            <begin position="3"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="249"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="281" mass="31948" checksum="52B4EA957D56970F" modified="2019-04-10" version="1">MGKASVHWFRHGLRLHDNPALLESIMACEKFYAIFIVDEDATEPMGYNRMQYLTESLRNLDAQLRALGGQLYVMKGEPTVIFKILHAEAGMARLTLEQDCDATWDKHDKVVRRLCEQLGVEVVEKMSNTLWEPSKIIEANGGEPPHSYEMFMVSASDIPLQVTIRRGRRAVAKPRSGKMSSYGELTDELAAKIGKELGYYPENNELTAFEGGETAALALLQERLKVEEDAFRDGYILPNQVNPDILGPSLSMSAAIRFGCLSVRKFYWEIQEIYFRLHRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPA1</accession>
    <name>A0A3R7QPA1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Transient receptor potential channel pyrexia</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_007848</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002001">
        <property type="protein sequence ID" value="ROT73709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPA1"/>
    <dbReference type="STRING" id="6689.A0A3R7QPA1"/>
    <dbReference type="OrthoDB" id="7464126at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052076">
        <property type="entry name" value="TRP_cation_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143:SF1">
        <property type="entry name" value="ION_TRANS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47143">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="179"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="361"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="692"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT73709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="712" mass="78218" checksum="3DA84E0DEF6583B9" modified="2019-04-10" version="1">MSFPKSAVQKQWKILEGAVRRGDVSRVSSILDDNPDLSAVPGPHSLLHSAVDSEGDCTALLRKLLDAGVPPDTQSLATIGALHLAAMKRCCNCMKQLLDSGADVDLKDIQDRTPLFYAVNHTRGGSGQCIQLLLEKGSSVNATCEGRITPLHVAAEVGNVTAAQLLLKAGAFHGARDKDGCTPLHLATTSGTVEVLLAGGADVTAKDNALQTPLERVVQFYPTVAQTLLDAGVEVRGNPQEKDLRVFFHLNTVTGGSSPCEVDLLDKIEDYGHYDLLKHPLCEIFLHLKWYHVRPLFYILSFLRVTMIVSLTSYLTLQRRVERKEAGEAANCSVWNGGLDDLLSDDWLNVGITSMRVLAGLLVGLFVVWELVRLLALKFQFWRRVDSPISIVFFVCSAALIIKDCDIEGWEKHLGCLAVLTGWLQVTFILSHSPDMGIYVQLFKVVALRMTKFTVVYLPIFLGFALCFRVTFDKNGATFATPLSSGIKALAMMSGELDYNSVLGHHKPVLPGTREIIFCFYVLLIAISTVNLLVGLAVRDIQLLMKKAGVNRLAVTVLLEIQIDEFFNSALASCLICRLLLRPLKDMTSLLPNLAVKSLKVGRSSFRPRGTIADFGAQGRAARKLNEAEKYYNVFICPNRTEAPGRVYRSLTPNEFCSEEFTERPAGYTLPSWIVRNTKLLVSSDRFRRKVEGGEGGKQAQGEASILSSGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVB5</accession>
    <name>A0A3R7QVB5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001225">
        <property type="protein sequence ID" value="ROT79553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVB5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="40128" checksum="40E212EB9245CFF6" modified="2019-04-10" version="1">MQIREKRHFMRAEWRMNNLDKHREGLATAEQMSDAEAGQSTVSTCTLPGSKQQQPVCREPFSVRFAHASETRIRTYSRHNTHRSDFFWFLSVHRQLPPSLSLSHSLILILFLSLSLSLLSSLFPSLSPPLTSSLSLSLSPYLPFSSSLSLSLSPSLLLTSSLSPSLSLSLSLSPSLLLPLPLSSPHLLPPPLFPSPPPPSLHPLLSFSLLLLPSLPPLSSSPPPSPLSLTLSLPPLSSPSPPPSLSSLTSSLSPPLFPSPPPFPLLSSLHPIPPRSITPSSPSLPKAIPPFNAHAKGEQDTRGIAEHAGGTHTRRNQYALCNIINSGALPLALSFPTEATETQVPYTMFTQVSGSPTLVLPPPPPPLGSPMLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVL5</accession>
    <name>A0A3R7QVL5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UMP-CMP kinase</fullName>
            <ecNumber evidence="9">2.7.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Deoxycytidylate kinase</fullName>
            <shortName evidence="9">CK</shortName>
            <shortName evidence="9">dCMP kinase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Uridine monophosphate/cytidine monophosphate kinase</fullName>
            <shortName evidence="9">UMP/CMP kinase</shortName>
            <shortName evidence="9">UMP/CMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001364</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>CMP + ATP = CDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UMP + ATP = UDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>dCMP + ATP = dCDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.14" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01001177">
        <property type="protein sequence ID" value="ROT79886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVL5"/>
    <dbReference type="STRING" id="6689.A0A3R7QVL5"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000315">
        <property type="entry name" value="Adenylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03172">
        <property type="entry name" value="Adenylate_kinase_UMP_CMP_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006266">
        <property type="entry name" value="UMP_CMP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01359">
        <property type="entry name" value="UMP_CMP_kin_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="9">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="36"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="111"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>CMP</name>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>a ribonucleoside 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT79886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="212" mass="23931" checksum="1EE50989996C3056" modified="2019-04-10" version="1">MSEFKSCMFLNRILRGVQSLIMASKYNIVFVLGGPGAGKGTQCSKIVDKFGFIHLSAGDLLREERAKPGSEYGELIENHIKNGTIVPVEITCSLLERAMKDSGKMDFLIDGFPRNQNNLEGWNKEMGEKVNLKFVLFFNCPLEVCTQRCLDRGAAGSGRSDDNLESLKKRFDTYMNATMPIIEHYEEQDLVRKIDATRSPDEVFEDVEKLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QZS6</accession>
    <name>A0A3R7QZS6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000443">
        <property type="protein sequence ID" value="ROT85124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QZS6"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12769" checksum="FFD4EFC5509A95E0" modified="2019-04-10" version="1">MIPNYIEFKESIYRALPIKEMHQYRHIFFSLLFGGGFVMYFAAVLIIKTKIEEEWSYWCEADGLLIVLTALVGLAIFYFQVLKRLLGKNHPLGRAFNTYVVASVNRISSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7R0F4</accession>
    <name>A0A3R7R0F4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative xyloside xylosyltransferase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000162">
        <property type="protein sequence ID" value="ROT85866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7R0F4"/>
    <dbReference type="STRING" id="6689.A0A3R7R0F4"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140560">
        <property type="term" value="F:xylosyl alpha-1,3-xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042465">
        <property type="entry name" value="XXLT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46612">
        <property type="entry name" value="XYLOSIDE XYLOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46612:SF1">
        <property type="entry name" value="XYLOSIDE XYLOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="454" mass="51335" checksum="A2BA2CF03B75E401" modified="2019-04-10" version="1">MLLRLRLLGQAIFLLVVAASLILLFAGRELRTSPVDTSPVAENPSPSLQEAVPLSSQENDLLYRPPLDIALIFTHAKDNAPFQYKLRVAVGSLLHAASAPLRLHLITDDDGFHIASQIINDVQASSQLDSRYVKLVYVAAEDFIPEIESSVTVLQDFFTTRRDAYYRDALFFFSLFLHRLLPGLERIMLMDIDIKVKGDIAELYSHFERFSPTNVMGMSLEQSPVYLHLLSLYRRSNPKTSLGSPPGQGGFPGYNSGIVLVDIERLRNSKIISRYLSRSTLTEKTKQYSFQGHLGDQDLYTLIAFDHPELFYTLPCGWNRQLCEWWRGHGYQTVFDQYFNCTGELKIIHGNCKTEIPENFEKGAEQGLHLLQRRPLLVLEGPCDELVEGRRLERHGLLQELEDVAEALHVALLAQGRAVVEAVAVLWLDVKGLELAVLAELEGVRETEKEMERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SUJ0</accession>
    <name>A0A3R7SUJ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001740">
        <property type="protein sequence ID" value="ROT75718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SUJ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="468" mass="50005" checksum="B7CD5A781DF52607" modified="2019-04-10" version="1">MLSALLGEIEGGEGKRGEEKGRGAISLQRDRVVFELPFAVSHGELPFLQSLIAVPQLPFPTLIAVPQSHIAVPPILSLPFPNLSLPFPNPSSLILLIAVPPIPHCRFPNPFIAVPPFPFSQLPVFPQSLIAVLPQSSCPPIPPCRSPNPPFRFQSPLPSPIPIAVSQSLIAVPQSLIAVPPIPPCPQSLIAVPPICVPNPSLPFPQPNPPLPFPQSLRSPIPPCRSPQSLIAVPPILIAVPNPHCRSPIPLPFLQSLIAVPNPSLPFLQSLIAVPQSLLPFPQSLIAVPPNPPIPPLPFPNLSLPFPQSLLAVPPIPSRSLRGFRSRPNSISSRYPFLPKGFSSALAIASLCSLHQKSSVGLACFRSAAFVHVADGSLQQIIRVILLSVFTHNPGKDGGSRSFDVLEGPLASQGSSSPSLNRHSRGLYLLRCQWSAGPALVICRSIDSVRNWIDSSSLPERGGDLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SV28</accession>
    <name>A0A3R7SV28_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001653">
        <property type="protein sequence ID" value="ROT76500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="679"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="841"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="877"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="963"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1268"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1486"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="215"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="320"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="603"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="698"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="754"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="963"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1195"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1301"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1312"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1328"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1350"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1388"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1498"/>
            <end position="1507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1639" mass="179726" checksum="BE16278A3BBCF0F7" modified="2019-04-10" version="1">MQHQLQKEFHQQHQLQKEFHQQHQLQKEFHQQHQLQKEFHQQHQLQKEFHQQHQLQKEFHQQHQLQKEFHQQHQLQKEFHQQHQLPKEFHQQHQLPSSISSTNCEGVPSAAPTAEGVPSANCEGAGSSIQQQQQLQKEFHQQHHCRRSSISRRRSSISSIPSAATAEGVPSAAPTAEGVPSAAPTAEGVPSAAPTAEGVPSAVQQHQLPKEHTNCRSSISSTNCRRSSISSTNCRRSSSTNCRRSSISSTNCRRSSISSTNWSSIKHQLKEFHQQHQLQKEFHQQHQLQKEFHQQHQLPKEFHQQHQLQKESAAPTAEGVPSATPTVPSAATAVPSAAPRRSSISSTNCRRSSISSTNCRRSSISSTNCEGVPSAAPNCRRSSISSTNCRRSSSAAPTAEGVPSAAPTSSISSTNCRRSSISSTKKEQQHQLPKEFHQQHQLQQHQLQKEFPSAAPTAEGVPSAAPTAEGSTNCEGAAAPTAEGVPSAAPTAKAAAPTAEGVPSAAPTAKEFHQQHQLPKEFHQQHQLQKEFHQQHQLPKESISSKKSSSNCRRSSISSTNCQEFHQQHQLQKEFHQQHQLQKEFHQQHQLPKEFHQQHQLRRSSISSTNCRRSSISSTKGVPSAAPTAEGVPSAAPTAGVPSAAPTAEGVPSAAPTAEGVPSAATLRRIALFAEGVPSTAPTAEGVPSAAPTAEGVPSAAPTASSISSTNCRRSSINSTNCRRSSISSTNCRRSFISSTNCRRSPISSTNCRRSSIGSTNCRSSISSTNCRRSSISSTNCRSSIGNINCRRSSISSTNSRSPISSTTAEEFHQQHQLPKEFISSTNCRSSIGNINCRRSSISSTNSRKSPISSTNCRRSSISSTNCRWSSISSTNCRRSSISSTNCRSSISSTNCRRSSISSTNCRRSSISSNNYRRSSISSTNCRRSSISSTNCRRSSISSTNCRRRSISSTICRRSSISSTNSTKSSISNINCRRNPTSTTNCRSRAISIALFAEGVPSAAPTAEGVPSAAPSEFHQQTIAEGVPSAAPLQFHQQHRRSFISSTNAEGVLPKEFHQQHQLPKESHQQHQLPKEFHQQHQLPKEFIAEGASAAQLPKEFHQQHQLPELEHRQHKLQEFHQQHQLPKEFHQQHQLQEFYRQHQLPKELHQQHQQQKESHQQHQLPMEFHQQHQLPKEFHQQHQLQEFYRQHQLPKELHQQHQQQKESHQQHQLQKEFISSTTADGVPSAAPTAEGVPSAAPTAGVPSAAPTGVPSAAQLQKEFPSAAKEFHQQHQLQKEFHQQHQLQKEFHQQHQLQKAFHQSHSTNCEGVSKEFHPQHQLPKESSAHQLPKSSISSTTAEGVPSAAPTEKEFHQQHQLPKEFHQQHQLRRSPSAAPTAEGVPSQHKLQEFHQQHQLPKEFHQQHQLPGVLSATPTAEGAPSSTNSSCLISSTNCEGVPSAAPTALNINCRRSSSAAPTAERVPSAAAQLQKEFHQQHQLPMEFHQQHQLQKEFHQQHQLQSSISSTNFPSAANAEGIPSAATTTEGVPSAAPTAEGVPLAAPTAEGVPSAAPTAEGVPSVALFAEGVPSAAPTAQKVPSAISTAEGIPPALPTAEAEPSAFNEGKEYGGGCLMETPVCSTPKELVLLMELLQMCLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T0A6</accession>
    <name>A0A3R7T0A6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Crustacyanin subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_023027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T0A6"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19436">
        <property type="entry name" value="lipocalin_crustacyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018384186" evidence="3">
        <location>
            <begin position="17"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="4">
        <location>
            <begin position="37"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT83844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="210" mass="23897" checksum="44B3A7F0D26862D8" modified="2019-04-10" version="1">MFSTLVAATLVALVSADGIPDFVVPGKCAKVANQDKFDLRKYSGRWYQTQIIDNAYQPFTRCIHSNYDYSDSDYGFKVTTAGFSPSNEYLRMQGKIYPTKDFPAAHMLIDFPTVFAAPYEVIETDYDSYSCVYSCIEMSGYKAEFGFVFSRTPQTSGPANDKCASVFRKNGVDFSSFRCCSYGRMRLQSIDIKFVTYIVTYIQTMYRNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAR4</accession>
    <name>A0A423SAR4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative collagen alpha-1(V) chain-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004269">
        <property type="protein sequence ID" value="ROT61257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAR4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24637">
        <property type="entry name" value="COLLAGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24637:SF421">
        <property type="entry name" value="CUTICLE COLLAGEN DPY-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="284" mass="30463" checksum="EB2171027A9F68E6" modified="2019-05-08" version="1">MRRTRRTCRTQGRGGQARAPGIPGHSWPDRSARPKGNAGPPGFPGAVGEPGKQGPKGNPGKDGDDGKVGEPGPPGSPAHPARWGSRAATESRVLRGRLACRGPQGSRERKETRARLDLWGLRVPLGPRVFLDLRGCLACEDLLDLLATWVFRARTEPQGNQVFQVSRVSRARRAPRPPRAEGTPREIGISGPKGDMGEKGEPGKNGPQGPSGFKGEPLLFQRDAPYDPDDSGRFKRSPRLNLRPRGKVALPAEEVGEVARSSLAPDSLSGKGGRRRDSRGTIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBK0</accession>
    <name>A0A423SBK0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CUB-serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004122">
        <property type="protein sequence ID" value="ROT61533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBK0"/>
    <dbReference type="OrthoDB" id="6339452at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051333">
        <property type="entry name" value="CLIP_Serine_Protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24260:SF145">
        <property type="entry name" value="FI17609P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019384968" evidence="4">
        <location>
            <begin position="19"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="42"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="196"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="433" mass="46899" checksum="62A020423A2D9D4C" modified="2019-05-08" version="1">MGAFAFFLLAASATLALGAGRQPSRSASPDTFVQLRTTKGKCGGDAVLADGQTVKIEGGRRIWKNRLCSWSVSGTDPGTTFEVRCPVFDLPWSEGCKTSRLMVGDGTGNSETLCGRGGKHLILKSNRMWASFLHRKRRRAKGFQCTVTAVRGNKIPALIHGAVGPHLPATADEKPKGKDPDFSSDPTPGTSCECGVRGNDTLQYPWLANIKLNYDDNNSFAVTTISPYYSGAVINSRYILTAAKCETNETSIPWEALEVGLGNYDVPIEGLVGTEQVFHVEEVISHPCEPDQEMGIALLKIREEINITKYTPVCLFSDPDENLIGTTGLMIGQDFLTGLWDQEVPIVSSTKCQSSETFCADFGFSEVPTCLGDIGGPLHVEEEAKFFQTGIAIYGYDCESVRPYASVAHHYEWIISNTADALSCGDVAGRSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBT6</accession>
    <name>A0A423SBT6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020512</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBT6"/>
    <dbReference type="STRING" id="6689.A0A423SBT6"/>
    <dbReference type="OrthoDB" id="6138663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfotransferase" evidence="2">
        <location>
            <begin position="83"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="377" mass="42804" checksum="671E42AD4A43E4A2" modified="2019-05-08" version="1">MSKVGTTAACGPTSCNSAPTLVTSRTAPPSRMGRRPVVLALLALLVTWSLLQLLCQLGGSLLRRNTSQPVYPDGTRHRRAHSQVLLWTQIRSGSSFTGRVLSLGTRTFYSEEPIRVHNHALGRDVGAAAAFLKDILLCRFSRHLEYFKDYITWHFQDLKVKYLCEFEPRLCSSPFTYEAFCRAAPVVVVRVVALALRAFIPLLEDDELDPKVVHLVRDPRGALSSRRSLPSYAHLYEEESNVSAVCERYREDLAAAATLRQRFPERYILVRYEDLALNPEREVRRLYEFAGLPFTPFVSQFLFDHTSGLQTREVKDAPFSLARNSTEVADRWRDRMSYEDALAIQEQCEDVLQGYGYEVFRSRREYSRRGGAAGAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBU7</accession>
    <name>A0A423SBU7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sorting nexin-9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_020529</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBU7"/>
    <dbReference type="STRING" id="6689.A0A423SBU7"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000004">
        <property type="entry name" value="Sorting nexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019497">
        <property type="entry name" value="Sorting_nexin_WASP-bd-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45827:SF1">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10456">
        <property type="entry name" value="BAR_3_WASP_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="PX" evidence="7">
        <location>
            <begin position="143"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="58556" checksum="F00F9CF379CD7284" modified="2019-05-08" version="1">MPLPQEPSIPGGTWGGEWSADAFRKELMDEQVRPEDDAWNNPWDPRGTELRDRPGSYSPPQSPMPPSPTSSFASTSPPNESASAPSSGRESRGSVKKSFNPFAKSSLDEFLIGPEKIPVTEKERIYIDDTENGPRWRPNPTEFTCSVSSPKKESKFHGMKSFIAYTIVPSETREERVRSERSCVSCRVSRVFSKQSVSRRRYKHFDWIHTHLTFKFPFLPIPPLPEKQISGRFEEDFIEYRMTMLQSWVERICRHPVLSQSETFHHFITCPNDEKMWKAGKRRAENDRLVGANIFQAIERPHKPLDILHVDATLDGFSTFLGRLDESVRLAQSTCLDQAKRYQMDFKREHDRVSFSFSKLSKAFETDPFNDGSGLSQALQEMSTAYEEIGTMYEMQPKHDWDPLSNLLFEYRGLIYSFSSVNSLLKDVLAKRRNAEKDAKEGRLEYDQLPHIINHSDTVAYAFEAELAHFQAVRTKDFNKAIASFLKGQISFYQKISDRLGTSLQKFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBX2</accession>
    <name>A0A423SBX2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_020487</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004016">
        <property type="protein sequence ID" value="ROT61709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SBX2"/>
    <dbReference type="OrthoDB" id="10053709at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042813">
        <property type="term" value="F:Wnt receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017147">
        <property type="term" value="F:Wnt-protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060070">
        <property type="term" value="P:canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035567">
        <property type="term" value="P:non-canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07066">
        <property type="entry name" value="CRD_FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015526">
        <property type="entry name" value="Frizzled/SFRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309">
        <property type="entry name" value="FRIZZLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11309:SF47">
        <property type="entry name" value="FRIZZLED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01392">
        <property type="entry name" value="Fz"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00063">
        <property type="entry name" value="FRI"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63501">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="101"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="199"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="353"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="487"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="627"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="773"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="940"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="1074"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="5">
        <location>
            <begin position="1216"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1266"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="106"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="114"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="151"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="354"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="362"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="492"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="500"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="567"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="632"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="640"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="707"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="774"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="782"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="849"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="941"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="949"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="1016"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="1079"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="1087"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="1154"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT61709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1341" mass="147361" checksum="709211644F46C425" modified="2019-05-08" version="1">MTIDRKKKKKTLLGNSDTRGHDTIRSEAASVSRPSPPLLNSVCELALKSDFRTACANALCCSKPVTMMARVHMLLVALSLLLASDSRGSSYRFSRGLAEGRSPPQCEPIVVSLCQNLSYTTTTAVSPHHTSQIEAEQYLYTRFSHLLGSDCSPDLRRFLCGMYVPECGGSGPVSALPCRGLCLTARDRCQESGNTFSWPETLRCDRFPVEGEDEECWNGNVGLSYNLTVMPNLLSHTTQEEAGMELHQFVPLVKVQCSPDLQNFLCSVYAPFCNAQGRPIPPCQRLCVSARDGCETLMNRFGFRWPESLECGKYPDSTECWDGNALSLPNGNVEVGQTPPPKDLTSSPLPGPKCEPLSVPLCKGVSYNHTLFPNLQSHTSQAEAALEMEQFIPLLRSKCSPHLELFLCSIYAPVCTILEKPLPPCRDLCVTLRRDCAGVIRRLGLSWSEIFECERFPSGNVCVSDVGTSVETSTRDPSPQVEGGGMSLSEKCEVLSIPLCKDMPYNMTIVPNLLNHNSQEEAGLQVHQFFPLVKVQCSPDLQNFLCSVYAPFCNAQGRPIPPCRRLCVSARRGCKSLMQRFGFLWPESLECSKFPEGTNCWDGKTGISTASTSEVEETSLIVPDTHVSEGKCEQITIPLCKNLNYNSTIFPNWLNHESQEEAGMEVHQFVPLVDVQCSPDLQNFLCSVYAPFCNAQGRPIPPCQRLCVSARDGCETLMNRFGFRWPESLECGKYPDSTECWDGNALSLPNGNVEVGQTPPPKDLTSSPLPGPKCEPLSVPLCKGVSYNHTLFPNLQSHTSQAEATLEMEQFIPLLRSKCSPHLELFLCSIYAPVCTILEKPLPPCRNLCVTLRRDCADTIRRLGLSWSEIFECERFPSGNLCVGDVGISTDTSTAVPSPPQTDHPGTQLLGLPSFPNSNVEVSQTPPPKDLTSSPLPGPKCEPLSVPLCKGVSYNHTLFPNLQSHTSQAEAALEMEQFIPLLRSKCSPHLELFLCSIYAPVCTILEKPLPPCRNLCVTLRRDCAGVIRRLGLSWSEIFECERFPSGNLCVGDVGTSVETSTRDPSPQVEGGGMSLSEKCEVLRIPICKDMPYNMTIVPNLLNHNSQEEAGLEVHQFVPLVDAQCSPDLQNFLCSVYAPFCNAQGRPIPPCQRFCVSARDGCETLMNQFGFRWPESLECGKYPDSTECWDGNALSLPNGNVEVGQTPPPKDLTNSPLPVSKCEPLSMPLCKGVSYNHTLFPNLQSHTSQAEAALEMEQFIPLLRTVPSPPTDHPGTQLLGLPSLPNGKVEVSQTPPPKDLTSSPLPRPKLSVHLIWNTSCAAFMPLCAQSSRNLFLLVEAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBZ0</accession>
    <name>A0A423SBZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_020485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004016">
        <property type="protein sequence ID" value="ROT61707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBZ0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT61707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="581" mass="66353" checksum="16BDB7E113D171AD" modified="2019-05-08" version="1">MFTPAKGISPHVACPSPHFPSLHLPIISFSFTSPSLQLNSSYYHFLFTHFTFLSFHIHSHLLPFLHFTLLSFHIHSLHLLFNSLHLITFSCSFTSPSLQLTSPSYHFIFIRICFLTLPFPHFTFRSFHFHSLHLLFNSLHLIISYSFESSYRPLTSPSYHFIFILFTFPFPSFTFLPFHIHSHLLLNSSPPLTSPSYHFTFIHFTFSSTHFIFLSFHIHSNLLIDPSLPSLHLPIISFSFTSPSPNLTTFLSFHIHSHHLPDPSLHLFNSLHLLIISYSFESSYRTFTSPSYHFILIHFIFPSPHFTFLSFHIRSHHLSSPPFFLLIISYSLAFSSRSPTSLLFAFLSSHIHSHHLPNPSIPLTSPFYFIFIHFTFSSNSYFSLRLPILSYSLTSPSQPFTSPRMIFLSHYVPSPHLLSHYLSHLLLFLHLPRSPYPCSLLLPHFIIFHFSFIPVPPSSYFTPSFLPISRPPLFPLPLLLLHAYLSFFLFPFPSSSSALPSLLPFSALYSTLSLPFPSSSSSLPSLLPLTPFTTSLPLPFPSSSSSLPSLLPLTAFTASLSLPTFLYLFLPPSSYSLPLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SE80</accession>
    <name>A0A423SE80_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003661">
        <property type="protein sequence ID" value="ROT62503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SE80"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="455" mass="47800" checksum="F1D8C4A600E1D62B" modified="2019-05-08" version="1">MKLDRNTSAADWAHLLSRLGSRLGSLLNWAHLLGGRLGSLLWAQLSGDWAHLLGGDWLTCSAADWAHLLSGRLGSPAQRPTGPAQRPTGLTCSAADWAHLLGGRLGSPAQRPTAHCSAPTGLTCSAADWAHLLTGSPAQRPTGLTCSAADWAHLLSGRLLLSGRLAHLLSGRLGSPAQRPTGSPAAQRPTGTCSRLGSDWAHCSATGLTCSAADWAHLLSGRLAHLLSGRLGSPAQRPTGLTCSAADWAHLLSGRLGSPAQRPTGLTCSAPTGLTQRPTGLTCSAADWLTCSAADWAQLGLGSPAAQRLTCSAASPADWAQLTTGSAADWAHLLSGRLGSPAQRRLGSPAQRPTGLTCSAADWAHLLSGRLMCITLRKNTSLTPAFYLSLSFTLFSSPPMHSPLISLPLLSSPPLPSFFFPFPPFYFLYHSSFVFYCLSFPFHLFSSFSSPLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEC8</accession>
    <name>A0A423SEC8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_019612</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003637">
        <property type="protein sequence ID" value="ROT62546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEC8"/>
    <dbReference type="STRING" id="6689.A0A423SEC8"/>
    <dbReference type="OrthoDB" id="6330646at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002287">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000395">
        <property type="entry name" value="zinc finger protein 513"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13465">
        <property type="entry name" value="zf-H2C2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT62546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="146" mass="16671" checksum="DB9ACB929D13A0E8" modified="2019-05-08" version="1">MVRERGGPAKTQSSSSKCHQCPHCPFTTTQETLLFEHCLTHNWENPLSCPHCQYRPADASQMKRHMRIHTGEKPYLCPHCPYETADGSNLKRHIRTHTGEKPYSCPHCPYQTAMKGNLNRHIRGHMEKDSIGALPTADLTHFPPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SG72</accession>
    <name>A0A423SG72_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M60 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003471">
        <property type="protein sequence ID" value="ROT63230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SG72"/>
    <dbReference type="OrthoDB" id="10260387at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1250">
        <property type="entry name" value="Peptidase M60, enhancin-like domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.80">
        <property type="entry name" value="Peptidase M60, enhancin-like domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.30">
        <property type="entry name" value="Peptidase M60, enhancin-like domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035423">
        <property type="entry name" value="M60-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042279">
        <property type="entry name" value="Pep_M60_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031161">
        <property type="entry name" value="Peptidase_M60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051244">
        <property type="entry name" value="TCAF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15730">
        <property type="entry name" value="EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15730:SF5">
        <property type="entry name" value="SI:CH211-210B2.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17291">
        <property type="entry name" value="M60-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13402">
        <property type="entry name" value="Peptidase_M60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01276">
        <property type="entry name" value="M60-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51723">
        <property type="entry name" value="PEPTIDASE_M60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M60" evidence="2">
        <location>
            <begin position="227"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="610" mass="68858" checksum="19A0AA138CE6D29B" modified="2019-05-08" version="1">MAENSAASDMDTDQGDRSESHKRYLINQATHTCLAVIGGSSPENAVIGMTSPSDSREKQWYNSGGQWQWGGDRSYCLAPVPGDITVRLVKCASSTIKWTKDAEGRMVFGSRVLTVPPGRHRTRVILRSTINGTDQMWWTDAELRAFLKGASPAVYPFPSVHIAIYYQEIARGLLNQLAPLSEPLPFPRDVATFPGTVDDATPRVEKTFTLDLSVLGQASNLRMTTPRDWQATDLYVAAGDIFLVTLPESLPLEQARQITVCVGAHVDKLRPSSGTTKKSKWFKRMPVVSETFNVNPGINLLRSQYGGNLIFIFREGEVFLVDVNVKNVIRAPHFKLDKTTVHEWRVSRTSGAPHAVLESHRIVLVVRSSAVTSFAFPDQLMCRYEDIVDKLNSLAGFTESDPPPRGKYWLVNDLQISHGSAHAGFPVMVNRRIRNLAMFDTPHRWCVWHELGHNYQQARSWARAYGVESTVNLFSIYIGEKLFNKDRLKKNDKYRLASAAVDQGLTFEEANCWQKLVFLMEIKYAFPDKGWDMFRQLNRTTRALSKKEAELLASDHQLQIDYVYRTLSKIVGHDLILTYKRWGLSVSQDAQEEIQKLGLQKAPADLSVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SI75</accession>
    <name>A0A423SI75_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003363">
        <property type="protein sequence ID" value="ROT63864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SI75"/>
    <dbReference type="OrthoDB" id="6364407at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="750" mass="83301" checksum="FF084201914CCCE8" modified="2019-05-08" version="1">MDNADEGEGTTVDGVSSGRRLRTRISKVENEKDVSESGRGRGKQKKRKADVNIESLYLQENNREVCPTPLETIYETPQKQRKSGQRKGSAGGRISEEEESRPLGVRSSDDLPTSTVMSGKKIKRLCMFASHYYPTKQKVRLRKDRARKLNKLKGVKIPKGSAVTVQDVKEVLAKLSDEESEQNENNQNTNNYSVLGMNSSVSFYVGNIIRPDTNDEKFQGMIEDLQALQFNLPKESIAEENPTSEGTDPVLAALYNLDDPIPFLDDIPKAKPSSQSREKKARRRSSKLSGCLLPSLDRETTEQSTSSAKSGELLPNTLDSRLTDTDHIPGSMTETALNQITEYCASDIDVASTDTVKEETSALRCGNKRRKTTKERPLRSTGLTKRESEVSDSELVKKMRGSTSANKNDGEVHECTESPDFSCKGAELKFEVPALAASSDVLGNVFSENDLPSPTDFKPRVTRGRGIKRQRGKRRASGIQRSLYHNQAVLALAHCESSSPESFVKDSSSEDQQTLKCENSEIIKTSPTSPSTQMAALSLHCDLPFTSSTQDIETQAEQRKQRANRKNRRRSSRLSIGAASPSRSSDRINSNLGSYWDTASPKVSSDPPRLTSDFPHGEPEVQGSDHVSSTAAGSSNVSQQHFLHDKNTAILWDSPVINGQKAKELIFIIVLAMAFEAARIPGERAEEDRCDGLCSHRRDWFSMPLAQERRGAIIGLRGCRIKELQNLHRVRVHMDRNDPDIKIFGRQCHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIG7</accession>
    <name>A0A423SIG7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_018094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003347">
        <property type="protein sequence ID" value="ROT63992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIG7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT63992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="518" mass="58139" checksum="750FCDFB6973A06D" modified="2019-05-08" version="1">MSRGPLTLTSSSPAHSFSPLQVPLPFLPSLGSSLSLPFSGFFRGPGPSPSSPPPFLRLARRLSKSPLPLFSGSFHVPPSPSPLCGSPSPLSLSFRVPSTSLPLPPLFRAPPLLLSFPLLPRVPPCPLSFPSLESLQVPSLPPLLGLLPRSSYSLTSSGSLHFPSPSPLYESPSPLFLPFRVPSTSLPLPPLFMGLQFLPLLPSLWGLQVPSSSLFGFPPRPLSFPLLPRPRLEYESQFSPSLDLEYEQFSPSLNLELRTIFSQTEYDNLDLEYNNFSQPRPRECEQFSHSLDSKYESIFSPSLRTFEYEQFSHSPDLEYEQFLHPASTSNYEQFFSRPPTRMEQFSNADEQFSPSLTFARNNFFPQPRLECEQFSPSLDLGMQQFFFLPRPSTRRIANNFSQASDLESAKQFSPSLGPRMRNKFSPSLDLEYDNFSQPRPRQIANNFFPASTLDLCEQPIYSPSLDLECEQFSPSLDDACEQFLTASTTWPARTQQARRSCSLIQAIYQARAYLAMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKS4</accession>
    <name>A0A423SKS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017234</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKS4"/>
    <dbReference type="STRING" id="6689.A0A423SKS4"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03700">
        <property type="entry name" value="EF2_snRNP_like_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="19"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="848" mass="94391" checksum="8AAF0EE2FD0A0DA5" modified="2019-05-08" version="1">MERVNFTVEEIRELMDKRRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASSRAGETRFTDTRKDEQERCITIKSTAISMYFKLSDENLALITSADQKETGESGFLVNLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLEQEELYQTFQRIVENVNVIIATYNDDTGPMGEMRVDPSKGSVGFGSGLHGWAFSVKEFADIYSSMFKVPAGKLMNKLWGENFFNKKTKKWSTNKSTDNERAFNTYILDPIFKLFDAIMNFKKEETAKLLETLKIKLNVEDREKEGKALLKVVMRTWLPAGDTLFHMITIHLPSPVTAQKYRAEMLYEGPSDDLACTGIKNCDSDAPLMMYVSKMVPTSDKGRFYAFGRVFAGKVGSGQKVRIMGPNYVPGKKEDLFEKAIQRTILMMGRFVEAIEDVPAGNICGLVGVDQYLVKTGTITTSKDSHNMKVMKFSVSPVVRVAVEPKNPSDLPKLVEGLKRLSKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPLKKTDPVVSYRETVSAPSVELCLSKSPNKHNRLYMRAVPMPDGLADDIEAGKVTPRDDPKARKSYLCEHYEFDATDAMKIWTFGPESTGGNILVDVTKGVQYLNEIKDSCVAGFQWATKEGVLCDENMRSVRFNLHDVTLHADAIHRGGGQIIPTTRRVLYASVLTAEPRLQEPVYLCEIQCPEAAVGGIYGVLNRRRGVVFEENQVAGTPMFVVKAHLPVNESFGFTADLRSNTGGQAFPQCVFDHWQEMPGNPMDTTGSSKPYTIVCDTRKRKGLKEGLPDLANYLDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLT5</accession>
    <name>A0A423SLT5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proton-coupled folate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016944</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003143">
        <property type="protein sequence ID" value="ROT65109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLT5"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="43445" checksum="30B1084D196B6E11" modified="2019-05-08" version="1">MASEQKARPGRCARIRGALRNVTVEPLMLLDGVAFSSVHVYMENLQMERVCRVSAGLAADVCGALREHPQASVEVQRRFSVFALYNGVIAAALPLFFILFMGAWSDRYGRKVPLAAVQLGHCLHAAGYLLVALVPSWPPEVLLLVTLLDSLGGGAVSFLTAANAYVGDVSSEEARTSRVGLANSLWFLGGPVGTLMGTYIYSHGGYLYLFGTSLALSALAVTYVIAFLPESHGPFARRPAAQQKELEAGESAEGAAEARVTAAQMARDFFSPRRIVDSFRSTLRRREGNARALILVLIFTSLLRRVTRSPYVFAFTRHVLGWEAVDYSLWVTYKNLIATVGSLVAVPLLSGRLGVSDSVLAMVGATSGIVEYSTYGCVSEEQPLLIWIGECGTSSSSNLRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQ44</accession>
    <name>A0A423SQ44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GH5 family protein GH5E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_015683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002960">
        <property type="protein sequence ID" value="ROT66313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQ44"/>
    <dbReference type="STRING" id="6689.A0A423SQ44"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37398">
        <property type="entry name" value="ENDO-BETA-1,4-MANNANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37398:SF3">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT66313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="47297" checksum="6ED2238D9942E001" modified="2019-05-08" version="1">MDKLKDRRCKWCGIVYSYTESWQKNVRKISISLQVFLRDKQRRLIRSASRPRTAVATMPSWRIYLTLALAVGTAAAARLKVSGKDLTYNGQKVFLNGCNIAWHNYGYDFGNGGYDGTLEQWLREIGGSGGNSIRVWVHVEGYSTPRWDSNGYVTQCDQSGTFEADVKKLLDAAQAADVLVVLVLWNGAYLTNQAAVNLIWDDAKLDAYINNCLNSLVTQVKGHPALGAFEVVNEPEGSILVSSDSEPCYDTTTIGQSGAGWTGLYIPMERYRKDYFSSRDHTVSFLTPRFAVPPPGQFAQSDAFSNTHNHYTDECLNKAAGGSNAHLDFFQIHAYDWGDPGAQRAFTVDADAYGLGKPVVLGEYASVCGAGTSLPDLYSYAYEHGYSGGWSWHYVATGECSDTRQQQQEALKTLKDRSDHGLVSFPVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SS33</accession>
    <name>A0A423SS33_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_014945</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ATPase subunit F6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002868">
        <property type="protein sequence ID" value="ROT66994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SS33"/>
    <dbReference type="STRING" id="6689.A0A423SS33"/>
    <dbReference type="OrthoDB" id="8902296at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.110:FF:000001">
        <property type="entry name" value="ATP synthase-coupling factor 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.110">
        <property type="entry name" value="Mitochondrial ATP synthase-coupling factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008387">
        <property type="entry name" value="ATP_synth_f6_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036204">
        <property type="entry name" value="ATP_synth_f6_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12441">
        <property type="entry name" value="ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12441:SF10">
        <property type="entry name" value="ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05511">
        <property type="entry name" value="ATP-synt_F6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111357">
        <property type="entry name" value="Mitochondrial ATP synthase coupling factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT66994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="115" mass="12615" checksum="E58A2060BD397265" modified="2019-05-08" version="1">MPDVVPLAAVETRGAAVDTPPAQTDDCSALLKYIQHELLLKASDPIQQLFVDKIQEYSKKSKAAGGKLVDMTPEVEKQLQQELDKVARQYGGGPGVDMTKFPTFTFQDPKIDPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STY7</accession>
    <name>A0A423STY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Orthodenticle-related homeobox 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_014244</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002784">
        <property type="protein sequence ID" value="ROT67660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STY7"/>
    <dbReference type="STRING" id="6689.A0A423STY7"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007399">
        <property type="term" value="P:nervous system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000068">
        <property type="entry name" value="Orthodenticle homeobox 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45793">
        <property type="entry name" value="HOMEOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45793:SF5">
        <property type="entry name" value="HOMEOTIC PROTEIN OCELLILESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="6 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="7">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="229"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="242"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT67660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="316" mass="32742" checksum="09FA7D13A1BB04E3" modified="2019-05-08" version="1">MVSPRLHQPEEAAAGETTFTKAQLDVLESLFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQKQQAAGGEKTPRSKKATKSPPPSSTHTSQPSGQTTTGGLGAGASPPPSAGGHRDASPPSPPPSVSSAPPLPLTPSSSTTYNPIWSPAAIPPSGSASIPPMGDLMSPACLDRSGYGGVSQQAAAAAACYQSYAAPSYYSNMDYLTPMSHSQINVPVSSMASLNPMGGGGQQMGSHSSGSGLGSSSLVSTSLGTSSLGSAGSLGSSQSLSPRTPPTVNSLTPLPPDCLEYTDKNTAAWKSYQSFQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0C5</accession>
    <name>A0A423T0C5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_012050</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002524">
        <property type="protein sequence ID" value="ROT69728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10020990at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050457">
        <property type="entry name" value="ZnFinger_BTB_dom_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46105">
        <property type="entry name" value="AGAP004733-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46105:SF5">
        <property type="entry name" value="ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1577"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1605"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="163"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="476"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="995"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1374"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1504"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1423"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="394"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="441"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="481"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="508"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="573"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="614"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="704"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="889"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="912"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="954"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1015"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1109"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1136"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="1150"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1185"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1206"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1257"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1276"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1309"/>
            <end position="1321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1660" mass="181982" checksum="5A500997745F26BA" modified="2019-05-08" version="1">MNSMHNSFGGSGGYPGPYPGYVPPPTALPYYNGYPGDLTQVSSPYYGKPAAVPPGYSSGMGSYSAPPINNSSMYYQQYGLGYQYGYTKYGLGSGLGSSLGSNLGYSSELAGASGITPPSLGGLQAPTTDLGLTGSMFSKGKYNGGQGSPSPLTAAGLGVGHGGSSLLSPVTSTPPSPGPHNIPSGLAGTGATPSPPVDIIESKKDLDKMRRCQVCGQVFRLMSECLAHMKSVHAVHEAPLSVYSLQHSAGSHLTQSLSSTTSSGVPSALSTSLGPPNSTRAGGVGAPDSPLMALERMGWGEKQSLLPSLHASPSPLTPAYTPAPAVTPGPQHPSTQHLSSQHMSSQHPPSQHHPQHHSSQHSAQHTSNHHPASQTPPAPHPLMETSQDHHSARTPVSSLSMTYSMRTDTQVSQAHSRHAYSSPTCSVPENIPVSDTRTEIGVSSNYSKPRKTSSYSVSSIIGETKERVIERESNVAHEIPNSLTGQSPTRRQVSPAGRSSMPDGFEQRISQLKQQSAENSHCSRTASRTAAEEYSMPERETQGQKEQVVPDQHHSQQVDVHKGLQMSHGTPDSQKEDQKSLADERRDVPEDLSRHVPSSPTTIHGTLPSLHHVPSRETSHVQEEMMYEKTEKKRHLNSRMEDTSDSTRVNSPQQKEDDRTNSSIVNQQPSPQEVAKEPLSMEKATAVLKEQVSQIGKRSWSPAQSHYVQHQLPQQQQTSYQQTNQQQQPASAAQHQVPQPKHQQAQQSQHQQSQLSQQQSQLSQHQQPQAPQHLQGQQQQQQQQGQQVHHHQGQQSQQNSQQPQQSQHQAQQTQQPSQLSQSQQQPTQISQSQQTQQLSQPQQQSQLTQPQQPPQIQAQHPPQLSQAQQAPKPQPPPSQQPQQHHHPQQQRQPQQPGYSNWSGGVGSGYSGQGTQYPYGYSQGSNSQSSAGGQHPQSPMAAHKSSSYHPMPNNYASPYGASPGSGYPPDLAGRGPPGQQGYPAAHWYAAAGAGRMDSKSGWNIWGGQGHQPAGFPQSYAPYPYPAAGQQQQQKSQLSQQQSQQQHSQPQKQSQPAQPQLPQPSQSLQAQSQQILQSQIMQSQPQPPIQTQHQPPQPQGGPSQALQTQGPQPPQPKTPRPKTPQSQPQPQTAPPHTPQQQPHTPQTQPHTPQQPPHTPQQPPHTPQQPPQTPQQQAPQMQPPQVQPPSHSQPQQTPQQPQPQPQQLPQPQQQQQTHKQQPEPQLQMQPEVPPQSMAATPEPQAAEGSQEALGSRQSEQELEEALDQENAENEEEEQLEHYPPAERANSEDPDFQKEKLAAVDNHMDYQSKSKVTTRPPTNSVPKKPVYKIGPKSKTLAAKQYSQIDDLDDYKCTITVHENGSVNGYGVLPTHPSAVKGNSQSCDSSDSEINSEDGSPTFVQLRPAKRRRKSQSREGIFIGPKRVKQARLVRERQERRHRHLQEQLRQTELEEQIQAIRAEKSSEEDGPLGNMLVKSSIILADSQMEEQDNVEQCIATIKAQQMAVNSSESGNEPDSGDKLSSSSGQVKEVALHSEDRCKWNCLYMLECYVIVKDVQAHPQYGPKVQELLEEYQVDGQHKCKTCGEIIARKADFLVHVDTHKDFMPWECTICGSRFKIRGSLKEHLRYTHMKGRVPCLKCNKVFPTSTLLRQHVKFPSPQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2Y6</accession>
    <name>A0A423T2Y6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_010930</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002387">
        <property type="protein sequence ID" value="ROT70773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2Y6"/>
    <dbReference type="STRING" id="6689.A0A423T2Y6"/>
    <dbReference type="OrthoDB" id="5627at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT70773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="30912" checksum="9C9F62847068272B" modified="2019-05-08" version="1">MSSRQEEEVEEKPKISFKKVKGKSFRRRRESDDEEEPSPGEEESLLAKLEESKEMRKFRRRQGGISAEGLLVGEKVEKKEGPDDDPFKTKTGGMLDLNQVKNAKKTSDDAYDTGIGTSFSAETNRRDEDAEMQKYIEENLAKRKGLTSVEKQDDTPRHLTLEEAALHAVPDILRVSTTKKSEEMLSNQMLSGIPEVDLGLEAKIRNIEATEEAKQKLLRERMMKKERPSEFVPRTWLSTLYNTTDLILRRLGQQRKRRRRCRKLWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TCD4</accession>
    <name>A0A423TCD4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001928">
        <property type="protein sequence ID" value="ROT74154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TCD4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="44470" checksum="32A8F4C79668BF93" modified="2019-05-08" version="1">MRKLRQLGSLPHRRPTTPPLLLPPLSSLLSFPYSYPPYRCPPVPPKPPLLFSPPPSSPFLSPPFPSLPLFPPLPPPPPPPIDATPPIHRTFCLLIERSDEYSDHELYNERSICIAERCMSERADVYRSPGVEIMKGLVKSVILYYKYLSLYLFVYLFRGRAFSLSLPSSPPCSSSFPILSLSLFFSLLLPLSFLPLFSSIRLLSSPSIPLSFLSLFPSSFPPFHLSLSYLPSHLFLPPSFTSLPLSPSSLLSLPPYQLSPSPTLSSLSLSPLPTLPPFHLSLPHYLPSTHTLPPPSDSPSLPAFHLSLPSLPHAPPPPPPSSSPPHSTLSSLLPSSIPPLHPFLPSSTPPPPPPEPGKNPETPATLTEATKGNGGEHTRITRRKESTRASRGQPRPTTAQVRGAPGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TD68</accession>
    <name>A0A423TD68_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Solute carrier family 13 member 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007098</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001903">
        <property type="protein sequence ID" value="ROT74395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TD68"/>
    <dbReference type="STRING" id="6689.A0A423TD68"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015137">
        <property type="term" value="F:citrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015141">
        <property type="term" value="F:succinate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF82">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="580"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="214"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="624" mass="68169" checksum="4E2AD6C15B10D1A6" modified="2019-05-08" version="1">MTFLRIVAPQWRTFVLVLTPLLFGIFPLLIPTSEARCGYVILVMAVYWMTEAIPLAVTALIPVFAFPLLGILSTGKVCLVYMKETNMMFLGGLTVAIAVEHCNLHKRIALFVILHIGNIQHKNDVKYNVLVTFHQDSQQVKAAILMVRTVAGFMLTTMFLSMWISNTASTAMMVPIVDAILVELYSSRGKDGDQGEAAGDLSVAPQHQSQMELVTTNGKSGQSQEVSESPSRDAVGAKEAIAGDSSDSLTATPPDEECRAFKDMCFLALAYSANLGGTGSLTGTGPNLVTKAVLSSSFSEPTGLNFATWMAFNVPGMLVCVLLAWLWLQFLFMGLCGRKSSIQQTTPEREAAVKRLIREKYRQLGPMTHHEATVLTLFVVLVFLWLFRAPEFVPGWSKWFSSAFGEHLEVDDATPAMLIVFLLFVLPAKLNFWCFRDPNAPPTSSPACMTWDVVQKKIPWGVVLLLGGGFAMAEASKVSGLSVWLGEQLRYFDVMPKEAIVFIVCLMTAMLTEVASNTATASILLPVLKELALNIKVNPLYLMLPAAVCCSYAFMLPVATPPNAIVFAAANMRSQDMMKAGFAMNVICVLVITVMINTLGVALFDLQNMPSWANSTIVRPTIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TG42</accession>
    <name>A0A423TG42_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large proline-rich protein BAG6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">BCL2-associated athanogene 6</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">HLA-B-associated transcript 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">C7M84_006138</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="25 26" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Involved in DNA damage-induced apoptosis: following DNA damage, accumulates in the nucleus and forms a complex with p300/EP300, enhancing p300/EP300-mediated p53/TP53 acetylation leading to increase p53/TP53 transcriptional activity. When nuclear, may also act as a component of some chromatin regulator complex that regulates histone 3 'Lys-4' dimethylation (H3K4me2).</text>
    </comment>
    <comment type="function">
        <text evidence="1">Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="22">Component of the BAG6/BAT3 complex, also named BAT3 complex, at least composed of BAG6, UBL4A and GET4/TRC35. Interacts with GET4; the interaction is direct and localizes BAG6 in the cytosol. Interacts with UBL4A; the interaction is direct and required for UBL4A protein stability. Interacts with AIFM1. Interacts with HSPA2. Interacts with CTCFL. Interacts with p300/EP300. Interacts (via ubiquitin-like domain) with RNF126; required for BAG6-dependent ubiquitination of proteins mislocalized to the cytosol. Interacts (via ubiquitin-like domain) with SGTA; SGTA competes with RNF126 by binding the same region of BAG6, thereby promoting deubiquitination of BAG6-target proteins and rescuing them from degradation. Interacts with ricin A chain. Interacts with VCP and AMFR; both form the VCP/p97-AMFR/gp78 complex. Interacts with SYVN1. Interacts with USP13; the interaction is direct and may mediate UBL4A deubiquitination. Interacts with ZFAND2B. Interacts with KPNA2. Interacts with UBQLN4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
            <location evidence="4">Extracellular exosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001785">
        <property type="protein sequence ID" value="ROT75327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TG42"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071818">
        <property type="term" value="C:BAT3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002376">
        <property type="term" value="P:immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007283">
        <property type="term" value="P:spermatogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01809">
        <property type="entry name" value="Ubl_BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000154">
        <property type="entry name" value="Large proline-rich protein BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021925">
        <property type="entry name" value="BAG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15204">
        <property type="entry name" value="LARGE PROLINE-RICH PROTEIN BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15204:SF0">
        <property type="entry name" value="LARGE PROLINE-RICH PROTEIN BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12057">
        <property type="entry name" value="BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="16" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="17" id="KW-0143">Chaperone</keyword>
    <keyword evidence="13" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0221">Differentiation</keyword>
    <keyword evidence="14" id="KW-0391">Immunity</keyword>
    <keyword evidence="18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="15" id="KW-0744">Spermatogenesis</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="24">
        <location>
            <begin position="129"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
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    <feature type="compositionally biased region" description="Low complexity" evidence="23">
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            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
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    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021614"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    <evidence type="ECO:0000256" key="12">
        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022871"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00029739"/>
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    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00030033"/>
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    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00046003"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00046936"/>
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    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="PROSITE" id="PS50053"/>
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    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ROT75327.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1446" mass="153076" checksum="385217882AA8FB4E" modified="2019-05-08" version="1">MTGNAAMTAKYTVSGRVSIIRADGRRLNGACGGRGFDSRLRSARRVRDGTNPRECGGKLLGGVKDNYRMLPELNENLGELQADCASRPSLAGPTHSSSRQLFHLPRHSHNNIDALFNALVQVRRTTKMIDVTVKTLDSQNHRFSVPDDITVKQFKDRIASSVSIPADKQRLIYCGRVLQDDKKLADYNVHEKVVHLVMRAPPQANSRTAGGGASSSSNGAAGSSHHHHHHIRRQPGVEGAQVLLGSFVVPEDNEPIVPPTQGPSSSGVRLHQARTMLERASNVLDQMDRRLGSGEERTPSTESTSDNDQADDTRGERGAMETDAVEDTRPVAGESMSDEGVATASSTATTPPSDEMEALYSEMDALNNMDPTAMVPASMTPPMMGAINSSLAGGLAQAASAAVASALSSLARGGSSSGMSGSTNTGTGGASSSSTSTTDSVGAPPRGIPPGSLRTLTVRITNMRPTGSGGGRQNTPTTGASNTTTSNTTDNAASTSENTGSRSGSEGHEAPSGAGASGGATATVGDGQTVMTDAASLQQEQWLLWRVSEVLHFVSHAMHAISDIMVDLRRPPPRQLRARPIIPSPSCQAQINVTTSTDPTRVTISSRGGNRPSSTTVTSSANNVTSSSSTSNSSTPRPASTSSSTSSAFGTAHVEGQTTGGSNQVGSSASTTTSATTSAASSSSSSGATSSGSQTASAQARNLASMLNLGAVQGFPMDGGDLVLMEVGPHGITIDSLSAEGSGSAGGSAPTPELIRNLVSSITNQLGVNLSGAATSTSSTTSSSSTSSSTTSASSSTATSNVCSSTPASGQGVQRTAPARNSQAAGNSGTSTTNVTQTRVTHRPHVHVTPLNVPGMGMNQFDPFLPCQSHHIRPATRRRHQAQTQAQENGASENSQTRPQVGISPTASSSDPLAFFASLMAEAFGARQGSATQQQQHQQQQQQQQQQQQSQSSAADGGEPQISDQMFAQLVQGVMSQVSGSLNTEGNGSSSQQSGASLHEFLQPFDGGMFSEGDEDSLFYQLFNTVAMSLSIGDLVQLFFGRATTANQLRTPLQEFVRERALKGNQPTEENLDRAIDSVIHDLHPHLVLTAGDAHVHEGIDYVNTVHNFIRHRLHDIFNLVLNHTDAETFGPSLVSLVRRALWEFIALSLHCFTDGAQGLERVIQERVRSIMAGVSPAIQTWSVNTSIMQLRSMMSRMTITDDHIRRYVVSPDEGRRMEEERSRRLRDSESPAAEPTPLPQMTSHHSSTADNMVHVTPANVPAEEPMEVEEVGCMEEVITTGVEAELEIATEGATGGTEEAKEDESLTEEPPVTINVGSQPWHPAVPQDWIPVITRDVERQQRGVPDTNLSDAYLCGMPLKRRKLASQHKPHGTVQQVIQDTLRHSMRGVGVNRVVVESVAGEAASQLGESFAGHVRTSLRQRLNHNKDFKPEKFPKSEQHILKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGJ8</accession>
    <name>A0A423TGJ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxysterol-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_005877</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001756">
        <property type="protein sequence ID" value="ROT75589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGJ8"/>
    <dbReference type="STRING" id="6689.A0A423TGJ8"/>
    <dbReference type="OrthoDB" id="10053431at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015485">
        <property type="term" value="F:cholesterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13286">
        <property type="entry name" value="PH_OPR5_ORP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2720:FF:000002">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000030">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000004">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019453891" description="Oxysterol-binding protein" evidence="8">
        <location>
            <begin position="29"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="9">
        <location>
            <begin position="345"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="509"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="639"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1137"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="519"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="652"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1143"/>
            <end position="1154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT75589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1258" mass="140648" checksum="3A7E62FB8EC0AFFE" modified="2019-05-08" version="1">MNETISCYFGIVVLSVAVVLIRCPVTAAADVSEGIPHKRILRKNPQRESSGRILRQEARDSALSFSFPGYDAGADGATLRAPDTPNQGPPPPPWFPFNFPFYHGLPLSSPCFLFSLPSPTDIPLVFPEPPLGLPLAFPMASPYSLLSLPLWFPLNLPLFFPRSPLGPAYPVRTYPRSDAFSRPDLKRKSFARDPGHCHTRDQIDWVARGSQSAAQDLFGGNLSCLVAFISLGTVKLRVGSPFAWLDGPSPRCRGGNGQRVFSLADPRGRGVGGVEGSPFTALVPQPPSPLTPAPPFSPSHSLFLFLVDGTSLSRKESYKDQRRKYRCEKKRVARELLSTLKDPAVVVLADWLKVRGSLKGWTKLWCVLKPGMLLLYKSAKSSHWVGTVLLNTCELIERPSKKDGFCFKLFHPLEQSIWATKGPEGETMGESVPYGYGGAVVQPFPSSHLIFRAPSQAAGKCWMDALELAVRCSSILIRSMTSSSKADANNSITSSTLAADKWNESDYEKHFKDQDISDDSSPGQSADNSPVMTPQSTWRDCLIQLPGTSSVEVTPTHRAAMRGAAQRDPSPTPYYRKLAAAIHMADQELKGHPSNKRVSLTPEDAYFADQSQTNTPELSENQKKNYFFKAIPKVTEKNTLPFPLLNPTDLDDASHTDENEHHRESGHFSGADAMSGTESESEDGSHKGDEEPREDEEYDREDEMTPTESPYVPNFEGEMGEAGEQVEELEEENKSLIWFLLKQVRPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADLIPKAVQEDDPFTRMKEVVRWYLSGFYKKPKGLKKPYNPILGETFRCYWRHPNGSRTFYVAEQVSHHPPVSAVYVTNRQEGFSVTATVLAKSKFYGNSTSAILDGNVLLTLLPRGEDYVMNMPYAHCKGILMGTLTMELGGKVTIECEKTGYRTELEFKLRPFLSGYEANNMVSGKIKLGKDTLATLEGYWDGKISFTDKRKGEEEVLWHATPEVKMQRLQRFTVAMDQQGSFESEKLWQLVSLAIKNDDQVAATEEKTILEEAQRSEARERKAKCEEWVPKYFTQEPVSGVYVYKHSDLRPWDPRTDLFQYEFNYIISTKTRHKAPMIRTASIVSVDPKCEVVRKDGVQRLRGVLELAAAEETSSGDHDDLQDMPERPASTVPLPAKRQSHSLSPSILEALNKMLVTQDSLITEMKGLRQDVDGLHRRLSAMDSPKHRAALRASTSQESASPLSTQSWASILVALIFYSLIQWLVEKIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH27</accession>
    <name>A0A423TH27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001737">
        <property type="protein sequence ID" value="ROT75748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH27"/>
    <dbReference type="OrthoDB" id="6357295at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019462443" evidence="1">
        <location>
            <begin position="17"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="182" mass="20070" checksum="4770C11924F753C6" modified="2019-05-08" version="1">MMKALTFLAAVAAVSASPTRFLTNVTCVGADNVASCDADLQVCKNLFATEHDEQTRREIYRKCLDGNGFSHLDDVDPELLFSPTDVQALVLFGSEENHLAVKQCVLQERGEVRPDGTVDPQPFLDRLTPALNDTRPDLLDRLVSGAESCSPQSIEEWEVCIFYECFLGDFTTPVPTTVVPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKA2</accession>
    <name>A0A423TKA2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phosphotransferase</fullName>
            <ecNumber evidence="14">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_004517</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the phosphorylation of various hexoses to hexose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucose + ATP = D-glucose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:17826"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-mannose + ATP = D-mannose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11028"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:11029"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="14"/>
    <dbReference type="EMBL" id="QCYY01001598">
        <property type="protein sequence ID" value="ROT76879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKA2"/>
    <dbReference type="STRING" id="6689.A0A423TKA2"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24019">
        <property type="entry name" value="ASKHA_NBD_HK_meta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000095">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.367.20:FF:000005">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 14 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="15">
        <location>
            <begin position="5"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="16">
        <location>
            <begin position="205"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00050361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT76879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="49436" checksum="1925EC8A68DD7AE8" modified="2019-05-08" version="1">MASQKVKEICQELVLSQEALKEVCDRLQEEINKGLGKESNPEATIKCFPTYVRELPNGKEKGRFLALDLGGTNFRVLLIELGDKCTMESRIYAVPQPIMIGPGDGLFDHIAECLASFIKERNLGTELLPLGFTFSFPCKQEGLTKARLARWTKGFKCEGVEGRDVVELLKKAIAKRGDVKIKICAVLNDTTGTLMSCAWKNHNCRVGLIVGTGTNACYMEKIEKVELWDGDLEEPRQVIINTEWGAFGDNGCLDFVRTEYDNTIDRESLNPGKQLFEKMISGMYMGEVARQVIVRLVAEGLLFDGKSSDILQEKGSFFTKYISEIESDEDGDFNNCYAILEELGLNNATDADCANVRHVCECVSRRAAYLAGAGVALLLNRINEESVSVAVDGSVYRFHPHFHNLMVEQVSQLIKPGIKFDLMLSEDGSGRGAALVAAVASRTSAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKH4</accession>
    <name>A0A423TKH4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001586">
        <property type="protein sequence ID" value="ROT76952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKH4"/>
    <dbReference type="STRING" id="6689.A0A423TKH4"/>
    <dbReference type="OrthoDB" id="6353903at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844:SF1">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="43"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="800"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="814"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="845"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="883"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="895"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="924"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="946"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="968"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1008"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1025"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1066" mass="120674" checksum="1455FA3707A819F3" modified="2019-05-08" version="1">MNEFYTNSRILAVDKQGKQTSQAVDLVKDLINEESQGSLTILTKFLVEGEPGMGKTLLALKMAIDWANEKSLQQIKFVFLIFLRDFKGSLEQYIKEELLPSGFDEKFKKVWEYCKNNEEQVLFILDGYDELNKNDEGEIQNLLRYRDFQKSKVVVTSRPDVLKTIFQRTIVKGFSEEQMMEFIGKYFRLSNEEECGRMLKQIIERDYKYRKLAKRPLFCVLLCMLYDSERSVAKLPEKLSDMMFKIMLCLIKWNNNKVGGTDGSAGSADGNIEAFPPEYQEKFLSFGKLCMEALKTDKTRFSEKQIENYSLLVPLGFLSSDSENHVYGRKKFYKPVHKIFLEYLAGLYMADTIERDRREHKDFTTIYRHEHVLKFMVGVLGKRAHLALEGKRQQDFRHMKDQEILMLLREAGTTPDNCRAVARLLDRDYHRVYTSEVDFEGWSSILDQKFHMLKNLELVWRIKSNNPDQESSFNEASPELYRQFFSALRRNKSISMIRVRATQDGEPFSETKIKLFFSHFKEALEKENLKELEIKELNMNVLNGKVSSSLVQAVAEATCNSGRKALEALEVLRLDMFLDDDALHNLCDRLRNDSPKLKELQLTGLVHGRQGFKSLVELLKKNKNLHKLHLSMNRAQLQHDTSVFMSRDYTPTHMKMDLIRMSTYANRKSQDAFNQTVQESQEGCTLPDPTKELCYLFNDPLKTGVKFVHGAKGFCFVRDQDVRLPLPLCMGRGHQSIFHDLFSALPETNVQKLTLADPCLYLTKADLVCLGDAIRKTKHLNSLNLQGLYKSPSLTTVPLHPNPFIPTTTVTTTPPQPHPPPPSPPPPQPPPPPSTPPHHLYHYHPPNPLIPPTPTRTTSTTNPPPPSPPVECYMPVLLGLGQSPSLTTVHSTPTPLSPPPSSQPHHNPTPPPSHPHHHHPYPTTPTHPTLNPTLNPPIPTTTHPHLPLPPPSPPATPPPPPVTPPHPTTTTINPTPTTTSTTTTNPPPPPPQLSATCPSCSAWVSLPRQPPYPPHTTTPPPPHPTLTTTTTPTITTSHHHHPTSHPTPPQPPPPSTPPPPPPPPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNW8</accession>
    <name>A0A423TNW8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycine rich secreted cement protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001427">
        <property type="protein sequence ID" value="ROT78128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNW8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="45451" checksum="A4D5F1960ACC7E5A" modified="2019-05-08" version="1">MPASQTTDKKNAHATRGCKIDPHPEASDARANQNPQLAKNRNYGAKLNPRAQPKTPESSAKGVGDRRWHPTNQLNQPSLTRSSLSSRCATNCTRSASELWCKEINVYGNEHSPVLPLQKSPTTSSPSEHPHPLPNTFTPPPPPLRLDKPLSPPPTPKTTPLHPLPNALANYPTPSDPRPARHAWKTSTDGQASLSSALSLALSSGISFALSSGLSSALLFAFSFALSSAFSFALLFASLCPSCLLPSYFAPLPSPLPSHLPSPLPSLPFLLPPVPSLLPSPLPSHLPSPLPSYLLPPVPSLLPSLPRHLLSPLPSSLLSPLPLYLLSPLFSYLLSLLPSPALLFVLSSVLLFALSFALSSALLFALSFALSSALLFALSFALSSSLSSALLFALSFALSSVLSSALLFALSFALPSALPSARPPCYYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRR2</accession>
    <name>A0A423TRR2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_002164</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRR2"/>
    <dbReference type="STRING" id="6689.A0A423TRR2"/>
    <dbReference type="OrthoDB" id="10263353at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02669">
        <property type="entry name" value="Peptidase_C19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000068">
        <property type="entry name" value="U4/U6.U5 tri-snRNP-associated protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033809">
        <property type="entry name" value="USP39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="14">
        <location>
            <begin position="35"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="13">
        <location>
            <begin position="157"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT79146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="456" mass="53016" checksum="E8CC85863F31A9AA" modified="2019-05-08" version="1">MSTTEEKFIPPVNQAVKRELEDDVDDKRAVTKKSRQCPYLDTINRHMLDFDFEKLCSVSLSRINVYACLVCGKYFQGRGPNTHAYTHSVSDGHHVYLNLQTLRFYCLPDNYEIIDSSLNDIIYVVNPTFTKEYIAKKVNQSKMSRAYDGTLYLPGIVGLNNIKANDYCNVVLQALSNITPLRNYFLDPNNYSHIHHAPGTKGLAMFPLITRFGELVRKLWNPRNFKAHVSPHEMLQAVVSCSRKKFQFTVQGDAIQILSWILNSMHLGLKTPKRKSTIIYRCFRGTMNIYSQKILPVEIDEKERNRLLKCEEYQEKMEESPFLYLTCDLPQPPLFKDEKKENIIPQVSLYVLLSKFDGKTGKEYQTYKENILKKFQLTGLPPYLILYNKRFTKNTFYIEKNPTIVNFPVKNIDLTEYLTEEVKQKHPEPIYDLVANIVHDGEPEAGTYRCHILHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU38</accession>
    <name>A0A423TU38_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Glycine receptor subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_001308</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001169">
        <property type="protein sequence ID" value="ROT79969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU38"/>
    <dbReference type="OrthoDB" id="6515930at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="586"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="14">
        <location>
            <begin position="82"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="301"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="320"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT79969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="658" mass="73507" checksum="2A4FE7EE3F5A72F9" modified="2019-05-08" version="1">MPGGTRFENVSSSTPQVLHGDIVQVNVWDSHLAEADVKEMAACRFLGLGNIFSSDTFDVEIVGDVQQSSVGLDFLCRTSPHYVILPEERTFDATRTLCRLLNASMTVFSSSSENQNFLEEFAPFTDVCSPGTTWKLWLGITDAQEDGVWVDVETQEPITYTNFKMPYPIGGSHLECVLMLMDGSWADVRCKASKCGVCSLDRFSFLKLRGFCFDMESRTNFRLGGYLGGRPVFRGLHQLVIHWDAVSLHWSLVNIDEETLLARSTLPDVQSYPLGQNEWVAVEPVCGVPKGSAFNLSLSSCPESQFICNSGDCIDHSYRCNLRYDCIDGSDEDNCNIVFVGSGYRQHLPPRGTNDSTLRLTPEITITRITEVDDLQMAISLEFFVSLTWRDERLSFRHLDPERETSIPASDAAQMWIPDYQLLNLEAGQAKELEKTVTVTTADNATLPHFNSINRDIVFPGVYNNITSSTQFTARLTCSFDLYIYPFDIQECGIDIGLPKNYDGSVEFSDAERSARYTGPYNLALYTVKDVAFGPNSGAARLDLKFAHRQGVILLSTFVPSVLLLLVSWATLFVRLDVPTVRAPMALTTLLVLYTLFSNLSGSMPNTAAVKMIDIWFFYIIFLLFLNIMVHIFVEPFFEALARTATRVEAKGAMVPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVZ1</accession>
    <name>A0A423TVZ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001096">
        <property type="protein sequence ID" value="ROT80639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVZ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="40146" checksum="F82DFA2DD0AC4FCE" modified="2019-05-08" version="1">MRTSVAVKPSPHVFFLSGYISSLIFSPFYSLALFPLYSTPSLSFVPSPLSPLLFTFPPLSSLSLSSLFSSLSLSPLLLPFISLSSFLFLSLSLSLSLISLSLTSLTSLLLSLSLSLYLSLFSSPLLSLISSLPLSLYSLSLSTHHLSPLCFSFSLLPPFTPPLSSPIPPPLISTHPPPQLSPSALSFALSNHLSSLSLVHLLLSPSLSLSASTLSPPPSPLTSTLSGSSPLRLSPLPLLCWRIKNYRSLYLFFPSFCSLLRRASFLVPSPSSALISTSYYRTLSTTSLFLPSPFSYLLLPLLFSPPPFSSTPLLFSLSLLLSSTSSLLPLSLYCFLPSTIESSYLTHQHRASTAPESLISPLGFELPVSYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TWV9</accession>
    <name>A0A423TWV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001050">
        <property type="protein sequence ID" value="ROT80926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TWV9"/>
    <dbReference type="STRING" id="6689.A0A423TWV9"/>
    <dbReference type="OrthoDB" id="10015560at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39074">
        <property type="entry name" value="AGAP007547-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39074:SF1">
        <property type="entry name" value="AGAP007547-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="21057" checksum="9816528AD44968DB" modified="2019-05-08" version="1">MDQLPQHIHGSSTDKSKFLKSTVLGTVAGFLIPVLLPFFHLGIISHLWDEFNYKVDRKGCSCSCWDTIFKGIYERGPSGYKHIYFNITSNTFKIWMVTVLSILLIYESVKRTLRLHFSGQLRKSMLVLLIASVYPHYYSWWSYFNYWNDDFYRQWNHQLFFSITELISTLAVVYLLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZE7</accession>
    <name>A0A423TZE7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulatory protein zeste</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_025007</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Self-associates forming complexes of several hundred monomers.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000913">
        <property type="protein sequence ID" value="ROT81827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZE7"/>
    <dbReference type="OrthoDB" id="10346002at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028002">
        <property type="entry name" value="Myb_DNA-bind_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23098">
        <property type="entry name" value="AGAP001331-PA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23098:SF16">
        <property type="entry name" value="REGULATORY PROTEIN ZESTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13873">
        <property type="entry name" value="Myb_DNA-bind_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="71"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="512"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="529"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT81827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="667" mass="74187" checksum="99CCBCAA0FEF4CB3" modified="2019-05-08" version="1">MCDANSSEMVNGLPVKEESEVSLIEDCSREVKETGNGDALFEAKEVEDVTIKEEYPYDEEHMVIVDPLLTFQCKHCKKVFTTQCDLDFHMKEKHTEAKLLSCTMCSETFLEESDLMMHAKFHNHGNPCIIKSSPLLPDQLLQLVLLIKEREGILFGNKRGPILSARKTHTWAEIATLFNAKNLGQGALSVQQIKEAWEYICKRVREAEAAHLKQHGAAGDVPLMSTFTAPYMQLASHILTRECISGNQAPEECQSQDEPSANTPRTSSSPPRPKYRKILPNVPPPLETQDSESSFGENDHSESEEENSTGSLDPGRSSQPEQAEANAKPKDGNGTAVVSSMKDLLGSVSSTVGHQVLFTNMCVTRERPTVGSGMQKGQQEDRPERSSPLTESQQECLVALIRDKKDVVLCKSQEPKILNLKKRVWKEVAENFNSLNPGQKPRKPNQLKRSLDHIKRRVKEEQSKYRRRVLANEGGPPPDPPKFTEAMMSAMEIMGQELSINDISFVSATMPNANKDGPTHMATTELEPESSSTPAVNTTDAVPSNSASTSPVVPSTPSPSLEFSAPHVPSTSSILWQSDRDPGKKKSLQECYQIAQESQDDWLQTKKRLLEAEHQEKMKLYEKAGRLIDSVQQHIDSLGHSFSLFLAAGQKAYAEMAESYKRTAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0A5</accession>
    <name>A0A423U0A5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative muscle M-line assembly protein unc-89-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_024697</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000880">
        <property type="protein sequence ID" value="ROT82140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0A5"/>
    <dbReference type="STRING" id="6689.A0A423U0A5"/>
    <dbReference type="OrthoDB" id="6371610at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000032">
        <property type="entry name" value="palladin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050958">
        <property type="entry name" value="Cell_Adh-Cytoskel_Orgn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080">
        <property type="entry name" value="CONTACTIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45080:SF8">
        <property type="entry name" value="IG-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="50"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT82140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="14815" checksum="53803E81FE29DAE7" modified="2019-05-08" version="1">MSPSSLIQTYLEIRPCKGSDSGMYKCVIQNSHGSAETECEVSIRKCYEAPFFTNTFTRMDKLPGSEVKMSVRYDGVPKPELSWFHNGEPILHDGDKYRIRKDGDGQTLTVKELTYSDSGAWKVVAKNARRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0B2</accession>
    <name>A0A423U0B2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024722</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000882">
        <property type="protein sequence ID" value="ROT82135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0B2"/>
    <dbReference type="STRING" id="6689.A0A423U0B2"/>
    <dbReference type="OrthoDB" id="5948335at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF193">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="108"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="324" mass="35006" checksum="5BA2B9B93C45E8D3" modified="2019-05-08" version="1">MGIAQARKDLIGAVQRGDAAGVLAALESGGDVNAVVVCEDEVERTVLALAAFLGPRHLVPVLVEKGAKVDQRAGRTMTAIHTPRGRGGRGAEGSVEGRRGPQCPEIRYFNSPLHFATMTSNFNCVKVLVEAGADLNCKDIYHYRPLHIASRTNYLPIIKYLLESRCDRGARTVQGWTALHVGGMSGSEEAVKLLIESGSTWRRWTTTGALQPCSPTSVGRALVLVLREDLWASTSLSPAVKARQSMERYDIEQLVLTWASQDIEANKHLLRMNTPSPFDGHYQDHSGRTALHVAAENGHRGNVVSTGRLQDLPSSAHLCGADAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1Z0</accession>
    <name>A0A423U1Z0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000789">
        <property type="protein sequence ID" value="ROT82694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1Z0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="270" mass="29978" checksum="327C34ABE9C9B7A9" modified="2019-05-08" version="1">MGHSCLSLSVNEVPSARHPRPPRARLPSRRIPERALTTLTRMLGTSGRMGLQGSCLGFVYLVAYLTLVQTQATTEPTLSATFPTDTTTPEEFSESSTTEDFATTTDSAGTTPADTTFDDPATTANYRSLNTRSLSFNIKFEEEDRNVTVSWTNISPNSSNSYNVTVHCAEETEAETECGCEKCEEIHETTENTFLTFRARPDTNYSIEVVDLDSNYSERVFNRTRPLKVLQLPSVNATENKTSVDLQWAIDCPYTVPGNYSIFFNGTTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U349</accession>
    <name>A0A423U349_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Lutropin-choriogonadotropic hormone receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_023677</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000729">
        <property type="protein sequence ID" value="ROT83140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U349"/>
    <dbReference type="SMR" id="A0A423U349"/>
    <dbReference type="STRING" id="6689.A0A423U349"/>
    <dbReference type="OrthoDB" id="6356519at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008528">
        <property type="term" value="F:G protein-coupled peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016500">
        <property type="term" value="F:protein-hormone receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009755">
        <property type="term" value="P:hormone-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15136">
        <property type="entry name" value="7tmA_Glyco_hormone_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000181">
        <property type="entry name" value="Thyrotropin receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002131">
        <property type="entry name" value="Gphrmn_rcpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24372">
        <property type="entry name" value="GLYCOPROTEIN HORMONE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24372:SF74">
        <property type="entry name" value="LP13728P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00373">
        <property type="entry name" value="GLYCHORMONER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0807">Transducer</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="501"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="546"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="587"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="631"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="684"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="14">
        <location>
            <begin position="481"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="33"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="164"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="834"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="898"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="838"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="911"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="922"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT83140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="946" mass="102929" checksum="97F795946AE7FF06" modified="2019-05-08" version="1">MLFNAVVESNDSGWHCGKVTVALRVGLPQKHAEREMQRSYPPPFPNELQPGIRRRKRRSALRAPAGPPPSPPRKPPKMSSHRDEIPSAGGSQGSPERGRREDTPTPGDQRSLLIRGRETSKSSGRFLGSFSTDEREARMLSSTGNCGGDCVRELRNRHREAFHLKGRLPPRRFGSGPRGGNTDGGNRGGVGTSEDVGAWASVRGRRNDTREVNRGRTRRKSLNDGEKSDGAEEGEEGEGRQPVGEGKTGLGSKVASSGDPFHAGPGRDAGTPHIDREGGFPKEGFSEGFGGSGYYVINDHESGLDFNDPTGYNNHGFPDAHLQYGPHGAPEPPLDTGHLPRGPPGAEHPRLDHHPEHFEYPQGAFESPFDATHLPHYPDLDPPFGPIHYPDAHAPLGPPLDDNGGAPGHTDQDHHGTFLTSYITLDNTTKTKMICGGKISKNYRDVQCLPEPDAFNPCEDIMGNLGLRVAVWLVVVTAVFGNLAVMVVLMSTRFKMTVSKFLMCNLAVADLCMGIYLLLIAAMDLHTIGVYFNYAIDWQNGPGCKVAGFLTVFASELSILTLTVITLERWYAITYAIHLNKRLRLTVAVRVMVLAWLYALTMATLPLLGVSGYSKTSICLPMETQDVADQAYLLMLLTTNGLAFVLICVCYSKMYCSIAGNNLAANTSDTTVAKRMALLVFTDFACWAPIAFFGLTAVLGFPLISVTHAKFLLVFFYPLNSCANPYLYAILTKQYRRDLFILLARYGFCTKRAIKYKGAYSTNTWLNHNNVCVSGGAGGSGGPSRRISTLTQITTCGDVRSRLRDGSEESLGRPLSPIRVRSISAELAVPGATALGATDRRSSDVGRRLQPVAEIRDGQSPTKASSGPTGGSPHPIKNCHARTSFTPEQEALLLRYASNRQPLAKGSRSRRQAEADKDEIVPLSTYTPSTPDTLTTPVSPQRERPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3L4</accession>
    <name>A0A423U3L4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_023513</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01000703">
        <property type="protein sequence ID" value="ROT83306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3L4"/>
    <dbReference type="STRING" id="6689.A0A423U3L4"/>
    <dbReference type="OrthoDB" id="6369165at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000004">
        <property type="entry name" value="Chitinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF360">
        <property type="entry name" value="CHITINASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="4" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="GH18" evidence="12">
        <location>
            <begin position="101"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="11"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="326"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT83306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="399" mass="43858" checksum="EE220AE3986ADBAE" modified="2019-05-08" version="1">MILILISISISHAPPPPTPKHTSSQSLTTPPSLPLPSRSPTPFPTHKFTPSHPPNSPLHSHSLPSHFPPPFPPPPTKPPKKTHPPPSPPLPPPTPTTTTTQELREAFRPYGWMLTAAVAAGKSTIDTAYDIDDLANSLDFLHIMAYDYHGKWDRRTGHNAPLYSREDEPEEEKMLNVASTLKVYLDEGAPPEKLVLGLGFYGRTFNLADPQENGIAAPTLTTALAGPYTKEEGFMGYNEICEKQTTEKGLWTLVWQKTHQVPYMIRDNMWIGYDDPISVSLKVAYAQKLGLGGVMAWAIDTDDFQGVCSDTRMKYPLLRAINKALTANMNERPSETPRPTKPSLDDDDFDDRFDDSNTLDSREHESGRPSRVGGRGGSAVATPAVTVLLALLLTSLAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U666</accession>
    <name>A0A423U666_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000584">
        <property type="protein sequence ID" value="ROT84198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U666"/>
    <dbReference type="STRING" id="6689.A0A423U666"/>
    <dbReference type="OrthoDB" id="78947at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047134">
        <property type="term" value="F:protein-disulfide reductase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045108">
        <property type="entry name" value="TXNDC17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010357">
        <property type="entry name" value="TXNDC17_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452">
        <property type="entry name" value="42-9-9 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12452:SF0">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06110">
        <property type="entry name" value="TXD17-like_Trx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="42"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT84198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="154" mass="17764" checksum="BA79FDEAB133F07B" modified="2019-05-08" version="1">MVQKIAVEVLTPSWRPWNPLKPRKAGLRAIFRLEDIGRRELVPDCVTAEPVVKGAVDKAAPEDAVFIYVGVGGRDFWKDPNCVFRTDARTKLKSVPTLMKYGTRKDSRRSSAPRPTWLKCSLKMLREHMYMDAQQRRHIADLENHINDYKTNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U8J1</accession>
    <name>A0A423U8J1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000454">
        <property type="protein sequence ID" value="ROT85020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U8J1"/>
    <dbReference type="STRING" id="6689.A0A423U8J1"/>
    <dbReference type="OrthoDB" id="6355940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="9">
        <location>
            <begin position="55"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="10">
        <location>
            <begin position="156"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT85020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="38502" checksum="5AEF9AF00CCFD979" modified="2019-05-08" version="1">MNSPSLVATASITSPHRVGCQAGVQIGQACWELYCLEHGIYPDGVPYNDYGDGNLDPFFSETKEGRYVPRTLFVDLEPSVVDEVRHGVYRDLFRPDDLVTHTEDAANNFARGRYSVGQEVVRKVLNRIRKQAEACSGLQGFMFFHSFGGGTGSGFMSLLLEKVMEEFTSPSMLRFAVFPSPRMSTAVVEPYNAVLHASTTMEYDHCVFVFDNEATYNLCINKLHRAIAAIRVKKTVQFVEWCPTGFKLGINSGPPTVVPGGDLAKTNRAVCMLANTTAFREAWARVNLKFDLMYSKRAFVHWYAGEGLEEAELSEARENMAQLERDYEEVDGHDDDLMDNHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA97</accession>
    <name>A0A423UA97_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative very low-density lipoprotein receptor-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_009716</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000223">
        <property type="protein sequence ID" value="ROT85647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA97"/>
    <dbReference type="STRING" id="6689.A0A423UA97"/>
    <dbReference type="OrthoDB" id="6358638at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005041">
        <property type="term" value="F:low-density lipoprotein particle receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051221">
        <property type="entry name" value="LDLR-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722:SF5">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22722">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="4"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="120"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="139"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="191" mass="21133" checksum="BCFA73FD576257E0" modified="2019-05-08" version="1">MSTCAEATSTAPRNKCIAEHQVCNRYDDCEGGEDEINCPVNPPPCPDGSFQCPDGGPCILEQFVCDGYMDCYGSEDETGCTTCNGGFHCDDDTCVFEIYMCDEREDCPNGEEEAAEDCECRDTDFICDNGHCLPDYMVCDGKPHCHGGEDEANCGDAKQTRPALRPRRVLDPRRTRAQNALLAKLAKYRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRW3</accession>
    <name>A0A3R7LRW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003559">
        <property type="protein sequence ID" value="ROT62728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRW3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="564"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="593" mass="63054" checksum="D72B2B8B923A4AB9" modified="2019-04-10" version="1">MSYNPLFFTPVPVGVRLVGVLSLHATSPVMGSGNLHPPFHTPAPPSYLQHPHQPTPPPPTPHPPTLSCPGRSPQAFHHPPTHTQPHPTYTPPPHHTTPLSPASEGVYHPTPHPHPPPPTPTPPSFLKSGQRRGVLSPRPPVPSRRFVGQHEAVLPPSSSSFLPSSSSFLFLLPSISPPPPPTPTTSSIYFSSPPTLLLLPPPSPPLLPSFLPLIFPPSFSPSPQSLPLPPSSSSSPSSKIFCPPLPLPFLFLLLLSNRLFGNFPFFPPSPLLSLPSPVFSFLSSLPSSSLLFFFLPPSPRLLFFSLSSLPPLSPSSLSSSLFPPLSLIFPSLPSPSSFLFLPLFLPSPRLLFFFPLPPWLFFPPLSLSHPLLGSLRLLSRLSSQSVPLAARPCLSLSISHHPHLHSSLVCLSSSHLDTPSQPSLSTTALPSLSLLPVSLPPLVPESSSLPTPSLLLPPSSPPLLPLLSVLLLHQVLLSSVSLSTVSLGLILCSAFISLSFSLLLSSSPHFSLVLSGSSPALRSVRSQSISPFSSLLPLSSVSLLAISLSPSLAGRWQHTLVPRPHSPSSLPALSSPRRPPSPSSHPSPISLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWG0</accession>
    <name>A0A3R7LWG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative DNA repair protein xp-C / rad4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002950">
        <property type="protein sequence ID" value="ROT66353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWG0"/>
    <dbReference type="STRING" id="6689.A0A3R7LWG0"/>
    <dbReference type="OrthoDB" id="300780at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4/PNGase transglutaminase-like fold" evidence="2">
        <location>
            <begin position="318"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="48120" checksum="97964E2EBE3CE654" modified="2019-04-10" version="1">MSDWEEVGERDEVAEMEELLSGSQPGATSGGNVQIELDAPNVLWGIKKRKRRTEEEMIEDYLRKSVNRSIKEVYEHMHKTHLLCLFAHGRYVNQTLNSETLLGAALSIITDKNAYPPKRLDMNYLEKFVRWFSKKMVYKPSKLEEDYWDTPLEMMLAKRFESKIAICNRELVYMFVVVCRCLGMNIRLVLSLQPMSWKPSADALIRPSKKGEVSNAFEEPSTSQTLVPDIKESEEKVNKKEKQPNKKMLSSDTDEEPINKKKNKKSTEPKGQVLSKPQKRKSKTCADDDDSDFDPEEKKIKKGPKASTSHRRKSGEKRSSDGDSDEKDKKKKKTGKEDKDGKKRKSEGLLEWAEVYVEEEEKWICVDIARGKIHCVAEVQVRMPSSSAYITAYNANLTVKDVTRRYVSNWLYSEKKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZ21</accession>
    <name>A0A3R7LZ21_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Translocating chain-associated membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_013421</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002667">
        <property type="protein sequence ID" value="ROT68423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZ21"/>
    <dbReference type="STRING" id="6689.A0A3R7LZ21"/>
    <dbReference type="OrthoDB" id="3053196at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016447">
        <property type="entry name" value="Translocation_assoc_membrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12371:SF11">
        <property type="entry name" value="TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12371">
        <property type="entry name" value="TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005449">
        <property type="entry name" value="Translocation_assoc_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="12">
        <location>
            <begin position="114"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="335"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT68423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="373" mass="42966" checksum="3FAA0C627AA5BB03" modified="2019-04-10" version="1">MAIKGRKANKNPPILSHEFVIQNHADIVSCVAMVFVLGLMFQATAPLASVFIAVQHNATDMETTETPMTYTYGNKDLAAVFFYSLISIVMHAIIQPPLLDKVNRRLHLSKTKHSKFNESGQLLIFTAVSAAWGINILVKDNLVSDITSLWADYPVGHAQMSFMLKFFFIIQMSYWIHCYPELYFQKTKREDMPDRIQHATLYLVFCAAAYVLNFTHVGLVLLTLRFIEEAVLHACRLLYFAEKTNIANTGFRVWNVLFVVCRLASIIVAILTFHYGLAINEDQTLDISSGNFNTPPIRLNALVAVCLIQAWMMWNFIHFHLRQMRERQALAQVTRKRVTERKSKRNKKDDSKRYSEEEVNELPEVDQQTRKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZ82</accession>
    <name>A0A3R7LZ82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002657">
        <property type="protein sequence ID" value="ROT68558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZ82"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="437" mass="47755" checksum="1CDC7AD61BBB83E1" modified="2019-04-10" version="1">MTDLRGNPTNTPTPPTNTPTHNHTPTPAHPHLHTHSNPSTPAHLHLHTRTCQPTPVKPHLSPTPFHPHLSHPHLSHPHLSRPHLSHPHPSTHTSPTHTLSHHPHTYTLPPTPSPTSTFHPHLSHPHPSTHTLSHPHLSTHTSHPTPSPTHTLSTHTSPTTPTHTLPPHPLSTHTSPTHTLSHPHPSPTPLPPTSPTHTLSHPHLSHPHLSHPHPPTHTSPTHTSPPHLSPHTFPPHLTPLQQPTHILTPPPFHPTSPTHTHTSPTHTLSLPHLSHPHPLPPHTLSTHTPPTPLPTTPPPHLPTHTTHTLFHPHPLPPTPFPTPLPPTPSPTHTSPTHTSLPPTHNLSHPHPSTHLSTPSPHPLSTHTSPTHTPPTHTSPTHTLSHPHTSPTHTSPPTHTLPPHLSHPHPLPPTPAHPPPQRQVQHFRGRVTRGRQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4B5</accession>
    <name>A0A3R7M4B5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002281">
        <property type="protein sequence ID" value="ROT71541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4B5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="207" mass="23181" checksum="D54851273AC8CF18" modified="2019-04-10" version="1">MANTTQFCVVAEMGQNLDKTSHHSIHDEYLWQTPSRPSTSGTDAVTSVVNVFEDGVRYSFRRHSNRQRSINSGRRGSFVSSGGDGPSRMPVNYDRLPKGPARQRQSPKSFLGYVPKDSMNSLTKCVAEEQEEAQQECGWDDWRSRGDRRSVASNGRMNSVHSWPQPSTRLLQPEVVKDPRRLGAGPECPCNSYTALGDTQRQSDTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5X5</accession>
    <name>A0A3R7M5X5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002091">
        <property type="protein sequence ID" value="ROT72902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5X5"/>
    <dbReference type="OrthoDB" id="6512771at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="598" mass="65502" checksum="EF0131604DD4063C" modified="2019-04-10" version="1">MYKWPVLDFVQWRSDLWDLFGDVCSLDASPFDRHLSLEVCPSGYPSPGYVSLEVCPLGTRPPDTCPWRFVPRVPVPGYVSLGGLSLGYPSPGYVSLGGLSLGYPSPGYVSLGGLSLGYPSPGYVSLGGLSLGYPSPGYLSLGYLESVSACRRIRGREGHFPDMWRRLPQRRSQQRRNVRGRGRFWAAGGGGRGASRAAPPGPGSSRIGSSRMSSRASSRASSRSSHRPRRPSVRASKIRREVSPFAHLPFLTTPTLPRALTPSFPLFLSHTRPWLYRTARPWAFLRLLFSEWHSNLGGQIGQPLWFNRERDEEAAEAAAPPQWESSTLNRAELRAKKDARQGDNSGFSTVQRPSGGRKYSAESSASSEAPPPRVARTTSFKHRYFGDTDIESSHGVGAGPSVPDYRSLPNRSSRSAHRNAGKGKRATSGPRGVSPPSGVAGSAGSSLQSSESEVDSHGGSHASRASKASRVSTGSNRSVYLHATAVADIPVRRASEEVPSERGVNRQSKKVSRSFSLLAPWKPRHYREKYEVEYDNREAREARGEANNSKGALPPRPPRRPANEAPDSKKVNRSQSMYKDSRLAGWLRRRRNKEAKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M7W1</accession>
    <name>A0A3R7M7W1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative hyccin isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012279</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Hyccin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002557">
        <property type="protein sequence ID" value="ROT69512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M7W1"/>
    <dbReference type="STRING" id="6689.A0A3R7M7W1"/>
    <dbReference type="OrthoDB" id="18937at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018619">
        <property type="entry name" value="Hyccin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31220:SF1">
        <property type="entry name" value="GH21176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31220">
        <property type="entry name" value="HYCCIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09790">
        <property type="entry name" value="Hyccin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="329" mass="36387" checksum="5ABDB4C4B170DB00" modified="2019-04-10" version="1">MKEQRCPDLFENTVRQLFALARSKDERLREFVLLFAPSLLYIYLSSISFGEKKGVGSVEVALLALYNMEVLDEQGQPRIAPFRLPTLARQSVFHEPASLAPASFTVDSLQRLEAGDAETVRWGPPTQMTSVTAATRHHLATAIMVAFNARLATLPKIALMHLCKAASKIVSQGFNRPGHHHRSSYGSESSFSLYPRPTPRIPVTTELLAELLHAVYFAIPAERSLHDLPSLMSISMPLSHFHYSRFNEFASLGIQALEDLHMRAQYELFGDVLLMTNAIKNSLKVNPSGQPSDGPMGISVALTPLTTTAPLSKSFITNASFRTKKLPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9C2</accession>
    <name>A0A3R7M9C2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UPF0483 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LovG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002408">
        <property type="protein sequence ID" value="ROT70601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9C2"/>
    <dbReference type="STRING" id="6689.A0A3R7M9C2"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032526">
        <property type="term" value="P:response to retinoic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000073">
        <property type="entry name" value="esterase OVCA2 isoform X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="226" mass="25528" checksum="F2EDA1610F274F65" modified="2019-04-10" version="1">MAGNSLRILCLHGYGQNADVFRESLGGFRRFVKHHANCSFLSAPHPLESDNNLEKAEGRAWWFKKDEKEEIVYRGFEESVLAIEKHVQSCGPFDGILGFSQGATMVGLLCGLQQQKKLNFDFKFAMLFAGFCSRSQAHQEIYKEQISLPSLHVFGETDKIIPVEQGEKLASFFLNPTILRHKGGHHVPSSGTQKDVYRDAYRQFLDAFASSPFSDWSSKHLKPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MB26</accession>
    <name>A0A3R7MB26_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_009848</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002241">
        <property type="protein sequence ID" value="ROT71820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MB26"/>
    <dbReference type="STRING" id="6689.A0A3R7MB26"/>
    <dbReference type="OrthoDB" id="6501435at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11055">
        <property type="entry name" value="CYP3A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000182">
        <property type="entry name" value="Cytochrome P450 3A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050705">
        <property type="entry name" value="Cytochrome_P450_3A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24302:SF15">
        <property type="entry name" value="FATTY-ACID PEROXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0492">Microsome</keyword>
    <keyword evidence="10 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT71820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="502" mass="56865" checksum="6D416B97101223BA" modified="2019-04-10" version="1">MIATIILFNAAVFLLSILVLWKRRKHFKLLEKGGIPTPAPHWLTGHLDDVTYSPEKKCMVQRKHEWLQKYGNVVGYYNGGFPRILVADLDMLRDILIKDAHNFVNRPVVVSQSKMLVALRDQHWKDVRKIMSPVFSTAKMKKMMPLMSGCVEVLLQKCHQLASSGQEFDIYVTLQCLTMDVIDRCAITLGLQCINNPENEILENFRKLFNRPPSLVTRLMHTFPSLLTLISASMRLAGAGVHRQKNVIVEHLRVVVKERRERGGHGGVEKSIDALQMLIDASCNEQQDSGKTTLSEQEVVDNAFLFLAAGFETTSNALAYVAYLLALHPDVQEQVFEEVSQVVQAEGGLTYEALAKLVYTEAVAMEAMRIYPPVTGFVLRETAREWTYGGYTFPAKSEVEVPVWSIHNDPTLYPEPQVFKPERFLPEEKKSRHPMSFLAFGTGPRNCLGIRFAMMEIKLTLGTIVQHFRFKTCSRTEVPLPLVTRGALTHPRDGVWLTLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBW8</accession>
    <name>A0A3R7MBW8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein heavy chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_009091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002140">
        <property type="protein sequence ID" value="ROT72523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBW8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="49224" checksum="ABD259F6678C924B" modified="2019-04-10" version="1">MEERGKVEGMFTRKEHIGCRPKRSLHVHVERPFTFLHVPTFPFTFPTFTPRSTALHVHVERPLHVPSRSDLHVPTFTFLHVPTALHVHVERPFTFRPSRSFHVPRSFTFRQPFTFTLNRPFTFRPSRSFTFRPSRSFTFRQPFTFTLNGRSRSFTFRPSRSFNVPTFKRSFTFLHVPTFTFLHVPTALHVHVNGPSRSFSRFTFRPSRSFTFRLHVSYVPFRQPFTSRSRSTFTFRQPFTFTLNGPSRSFTFRPSRSFTFRQPFTFTLNGPSRSFTFRPSRSFTFRPSRSFTFRPFTFLHVPTFTFLHVPSRSDLSRSFTFRQPFTFTLNGPSRSVHVRSFTFRPSRSFTFRPSRSFTFRRPSRSFTFRPSRPSRSFTFHVHVPSRSSRSDLHVPSRSSLPTFTFLHVPSRSDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEL2</accession>
    <name>A0A3R7MEL2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Catrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001910">
        <property type="protein sequence ID" value="ROT74328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEL2"/>
    <dbReference type="STRING" id="6689.A0A3R7MEL2"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.740">
        <property type="entry name" value="Crisp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042076">
        <property type="entry name" value="Crisp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013871">
        <property type="entry name" value="Cysteine_rich_secretory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08562">
        <property type="entry name" value="Crisp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57546">
        <property type="entry name" value="Crisp domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ShKT" evidence="2">
        <location>
            <begin position="204"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="250" mass="28627" checksum="E687AA7F10333E8A" modified="2019-04-10" version="1">MVRHRPGWPAGIQYRSVDTQQPKVQKHIVGLHNILRAKVTPTAADMLAMAWYDTAAEQAQAWAEQCGSDSEADHPSVRWTSRYGACGQNVMVSARKRHWSFVMHNWWSGRRTFTYGGDSNNSSAVSAYTQMAWYNSHQVGCGFAECSEPGGKTFFRYVCNYCPSGNDPRRLSRPYTQGRTCRKCPDDCRSVCRKPECKLCTNACTYSDLWVNCKALDLQWHEWLCNTKTRNGVERFRNCRATCQCHKRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MEN2</accession>
    <name>A0A3R7MEN2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_001554</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001198">
        <property type="protein sequence ID" value="ROT79723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MEN2"/>
    <dbReference type="STRING" id="6689.A0A3R7MEN2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="92"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="190"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT79723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="278" mass="31722" checksum="C71546D8EF01D9EF" modified="2019-04-10" version="1">MDSRNTWYSWETPWYSRNHLVLLHPRNAWNTWYSVNHPPWVLLQSRNAWNGTPAPAIPGTPGTPGTPGTPGTPGSSGSTGGGVGVARPPPFTLMCYHDNKYRRHPLFCNSYYYCIWDGLNWNFPIFTCPAALIFDEETQQCSYPDDTKPCDAQLAPYPTPKPTKPVPEVTTPQPVETTTKKTWQVDESSNYACPAPGYYPFEGDCVRFYKCVELEDGSLKGLLYKCPSGYGYSEERQRCWPEEDLPACRRIIQDAHLRLETATPVYPEDLFWFFNNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHD9</accession>
    <name>A0A3R7MHD9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peritrophin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024272</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000803">
        <property type="protein sequence ID" value="ROT82571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHD9"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018669434" evidence="1">
        <location>
            <begin position="35"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="45"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="109" mass="12055" checksum="F4FAC5BE8A57D13C" modified="2019-04-10" version="1">MKKLFDYLDRRLEMKAVALFLVLALCVACRPCCAEEFTPCPDEVSAKCPAVDGDFPTFFAHPDDCSKGCECSKGKAWVIQCQEGLLWDDTVSVCNWASQVDCGSRPLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHI4</accession>
    <name>A0A3R7MHI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box/WD repeat-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024164</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000789">
        <property type="protein sequence ID" value="ROT82688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHI4"/>
    <dbReference type="STRING" id="6689.A0A3R7MHI4"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042627">
        <property type="entry name" value="FBXW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44436">
        <property type="entry name" value="F-BOX/WD REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44436:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="61"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="266" mass="29891" checksum="61C6C2069127B41D" modified="2019-04-10" version="1">MDKLISELVHLEVAEQQKVLSALVTPLSPEKQLSLLLPAVSRASGYVKWRLAVTLAWQDTPDLLELLPAELQVMVLQYLDGPSLLTACQVCQGWNRVLMNHGQLWLKKCQQLGVNMDLLSQGTNWHEVYVSSLRQLTSLKNGTAFVERFMQLQNCNKAVKAVDYQDGYLCTVSEEDYVNIWQLDLNIPILTFPVERAVSYIKFRPKQLLVCGHFVGILTSWDLSAMDKQSSVVYSGVNNHSRALGTKGHLDACHHSLTATLCHLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJH9</accession>
    <name>A0A3R7MJH9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">alkaline phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001393">
        <property type="protein sequence ID" value="ROT78375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJH9"/>
    <dbReference type="STRING" id="6689.A0A3R7MJH9"/>
    <dbReference type="OrthoDB" id="5818554at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="ALKALINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596:SF91">
        <property type="entry name" value="ALKALINE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601952-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="310" mass="34607" checksum="97B9817310865894" modified="2019-04-10" version="1">MAAGGESSSRQRCLGCRRVSLRLPKGREEPHKLVAGGQERAWEQRRLRVEPGGPPGHQHEQHEQPTTCWVGFEWRWASGLFAYSHMDYLVERDSSMDPSLPEMTRAAIEVLQRDSKGFFLLVEGGLIDHGHHGNKGIKALTETVEMDEAVEVALSMTSREDTLIVVTADHAHTMSINGYPSRHTDILGLADFSDEDYMPFTTLLYGNGPGYRDPVNGHRPDPTNDDLHDVNYRQPASVPMSSAAHAGDDVGLWAIGPHAHLFTGVYEQNYIPHALAYAACVGNGLTFCGNNRFRRNYSHRGRLQRWRPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK14</accession>
    <name>A0A3R7MK14_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Crustacyanin subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022993</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK14"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19436">
        <property type="entry name" value="lipocalin_crustacyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="214" mass="24348" checksum="BB4254D9D50C2CB5" modified="2019-04-10" version="1">MTTEVNDHSSAHRKRDIRAPGILVWSTTEKSCLPHSSLLPRGLVSADGIPDFVVPGRCAKVANQDKFDLRRYSGRWYQTQIIDNAYQPYTRCIHSNYDYSDSDYGFKVTTAGFSPNNEYLRLQGKIYPTKDFPAAHMLIDFPTVFAAPYEVIETDYDSYSCVYSCIDWNGYKSEFVFRLPVQRTTSAPPSSRKNGVDFSSFNEVAHTAECVYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKX5</accession>
    <name>A0A3R7MKX5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative engulfment and cell motility protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001240">
        <property type="protein sequence ID" value="ROT79467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKX5"/>
    <dbReference type="STRING" id="6689.A0A3R7MKX5"/>
    <dbReference type="OrthoDB" id="28413at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024574">
        <property type="entry name" value="ELMO_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11841">
        <property type="entry name" value="ELMO_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELMO" evidence="1">
        <location>
            <begin position="166"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="327" mass="37603" checksum="271680BDC677CF5D" modified="2019-04-10" version="1">MLTSFLELMDHGIMPWDDLQPPFIEKMVSFINVQVTPETRTLSTALTILENIVLNSQSKYTLVEKQITIPHLLQHISNSKKVEIQQSVLALINALFQKSEAQKRKYWAATLSSRQYRTILTNNVLIHAETGGIGADMAHQLYVLQQLLLNQYEERMNTSMDPSDQDATDKIKELRRIAFEEARVQKEYKKLGFRNDINPAQDFMETPPGMLALDNMIFFARNHWISGYAKLVLENCYRADSHECPFGRASIELTKLLCEILKIGEVPTEQGQTFHPMFFSHDHAFEELFSICIVLLNKTWKEMKATTEDFSKVLSVVRAGPDHSHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MM84</accession>
    <name>A0A3R7MM84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RNA polymerase-associated protein LEO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003094">
        <property type="protein sequence ID" value="ROT65366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MM84"/>
    <dbReference type="STRING" id="6689.A0A3R7MM84"/>
    <dbReference type="OrthoDB" id="20844at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990269">
        <property type="term" value="F:RNA polymerase II C-terminal domain phosphoserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007149">
        <property type="entry name" value="Leo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146">
        <property type="entry name" value="LEO1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23146:SF0">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN LEO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04004">
        <property type="entry name" value="Leo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="489" mass="55268" checksum="FEC770AA83C29162" modified="2019-04-10" version="1">MSDDESGDEAKKRKSDDDEDLGAEDLFGDADDISEDEEERKKDDRRSRSRSRSRSRSRSRSRSRSRSRSRTPGSPRLIVPDDEEKEDEGPPPETRIEAEIPKINTNLGRDIHFVKLPNFLSVETRPFDPDLYEDEIDDEETLDEEGRARLKLKVENTIRWRTVFDKEGNAVKESNAKLVRWSDGSMSLHLGAEVFDVYKQPLQGDHNHLFIRQGTGLQGQAVFRTKLTFRPHSTESFTHRKLTLSLADRTQKTVGVKVLSTVFRDPESSHIESIRRDEDRLKASMRRENKQRRVREKASSRGLTANYLEPDAYEEDDEGAISLAAIKNKFKNKQNDRAPIYSSDEEESDIETDKAKRLERAKHTIKDSDEESGSGSESGSESGSDRARSRQSTRKSSSRSRSRSRSKSGSRSGSGSRSRSRSRSGSRSKSRSRVKSRSKSRSKSRSKSRSRSKSKSRSRSRSRSSSRGSRSGSESARSSGKSGSGSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MNR7</accession>
    <name>A0A3R7MNR7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Snurportin-1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">RNA U transporter 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_024869</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the snurportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000901">
        <property type="protein sequence ID" value="ROT81959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MNR7"/>
    <dbReference type="STRING" id="6689.A0A3R7MNR7"/>
    <dbReference type="OrthoDB" id="10003593at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061015">
        <property type="term" value="P:snRNA import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09232">
        <property type="entry name" value="Snurportin-1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017336">
        <property type="entry name" value="Snurportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024721">
        <property type="entry name" value="Snurportin-1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047857">
        <property type="entry name" value="Snurportin1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13403:SF6">
        <property type="entry name" value="SNURPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13403">
        <property type="entry name" value="SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11538">
        <property type="entry name" value="Snurportin1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21974">
        <property type="entry name" value="SPN1_m3Gcap_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="13">
        <location>
            <begin position="10"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="313"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT81959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="48246" checksum="2A54BB3B527FF454" modified="2019-04-10" version="1">MEDLLNNLTGVSVTEHLNTPYAEHPYFALYKAKRTGSSQEERRKRVLDARKEARYDLLSHLRNIEEENVGSEGSSSDDSMECEKERVCYRRPKKYRNFLMMSEWLVDVPEDFAASYLSVLCPVGKRTLIVSARGRTRAYTKAGIMVNQFPSQLPGGCYYSKRKGYALLDCIWSETEKTYFVLDLVVWLNQSIMECETLFRFEWAKSRILEETPDATEISKYNPYRFVPLPHYDCSPETLTRLVNEPLPFRVPLDGILFYHKESHYTHGPTPLVGWLKAYMFPEILGINQVAQVHISERPAKYISLPAHIQYGKDRQQQKQEALNRKMEVSDENNKSPREKSKKVKDVKDNQENTSDMMEVSAENKKNPKGKSKKVKDVKEKSSEMMTRHQSYPDRFRRYKGAFPFLSSHTDATRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N3K8</accession>
    <name>A0A3R7N3K8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Integrin beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_005028</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Cell membrane</location>
            <topology evidence="1 18">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the integrin beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001667">
        <property type="protein sequence ID" value="ROT76381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N3K8"/>
    <dbReference type="STRING" id="6689.A0A3R7N3K8"/>
    <dbReference type="OrthoDB" id="410592at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005925">
        <property type="term" value="C:focal adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008305">
        <property type="term" value="C:integrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033627">
        <property type="term" value="P:cell adhesion mediated by integrin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000155">
        <property type="entry name" value="Integrin beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1240.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1510">
        <property type="entry name" value="ntegrin, alpha v. Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040622">
        <property type="entry name" value="EGF_integrin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057073">
        <property type="entry name" value="EGF_integrin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015812">
        <property type="entry name" value="Integrin_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014836">
        <property type="entry name" value="Integrin_bsu_cyt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012896">
        <property type="entry name" value="Integrin_bsu_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036349">
        <property type="entry name" value="Integrin_bsu_tail_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002369">
        <property type="entry name" value="Integrin_bsu_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057243">
        <property type="entry name" value="Integrin_I-EGF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10082">
        <property type="entry name" value="INTEGRIN BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10082:SF60">
        <property type="entry name" value="INTEGRIN BETA-PS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23105">
        <property type="entry name" value="EGF_integrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18372">
        <property type="entry name" value="I-EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08725">
        <property type="entry name" value="Integrin_b_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07965">
        <property type="entry name" value="Integrin_B_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00362">
        <property type="entry name" value="Integrin_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002512">
        <property type="entry name" value="Integrin_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01186">
        <property type="entry name" value="INTEGRINB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00187">
        <property type="entry name" value="INB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01241">
        <property type="entry name" value="Integrin_b_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01242">
        <property type="entry name" value="Integrin_B_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69687">
        <property type="entry name" value="Integrin beta tail domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00243">
        <property type="entry name" value="I_EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52047">
        <property type="entry name" value="I_EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="11 18" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15 17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13 18 24" id="KW-0401">Integrin</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5 18 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018743336" description="Integrin beta" evidence="20">
        <location>
            <begin position="19"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin beta subunit VWA" evidence="21">
        <location>
            <begin position="28"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin beta subunit tail" evidence="23">
        <location>
            <begin position="578"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Integrin beta subunit cytoplasmic" evidence="22">
        <location>
            <begin position="687"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="32"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="394"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="421"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="426"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="437"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="468"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="470"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="492"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="512"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="514"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="530"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="552"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="554"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="578"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="584"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="604"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR002512-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU000633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM01241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="SMART" id="SM01242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT76381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="733" mass="81505" checksum="5DA35770A39119AF" modified="2019-04-10" version="1">MKSMLIAVCLVAVSCCLAADVPGCQHETCTKCIRHRTCIWCSQNNTETRWPSCISDKHPDLEKWLDWCDTEAVEPGMTYSVIKDEPLSDDDEVENIVQLSPQEVNLTVRIQEPYNFTLTYSHSANYPADVYYMMDGSQSMADDKDMLYSLGEQLAEGMKEITNNLYLGFGIFIDKPVLPYISTVPKVTPPYSFKNALPLTSNASAFTDEVKRAEGGTNQDFPEGGFDGLMQAIVCEKDIKWRNLAGILRPNDKRCHLDANNEYNKAIVYDYPSVSQINEMAKLHRINLVFAITAEQEPLYARLSQHIEGATSGVLASDSSNVVDLLTSSLKDIISKVELTQRDHNSHVSVRFFSECKDGEMKERSSQRERLNPVVEVYPVGRQGSLQINLAMHCQCSCAKPGDKGYIVNAEACSRNGTSMCGVCECHEGFVGKACECYSNDDDGTGTISEDSCRQTNTSAVCSDRGQCVCGQCQCKKPADPSQNIYGDFCECTNYLGCTGNEGLICSGHGECECNECRCTGGWSGPTCSCDGNDDKCKNPDTDEICSGHGECECNKCNCQDDRKGKYCDDCPTCSGKCTDYKPCVQCKAFDTGEYDTNKCEADCTQYNITKHEAVEVENDQEKKCSFYDENDCVFYFVYTVRSSDNVTAIRVQEVKECPNPVNILGVILGVIGGVLLIGILALIIWRIYASIQDRREYSKFILSRNEEQWTNNQNPLYKEATTTVQNPMFGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NQE7</accession>
    <name>A0A3R7NQE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003345">
        <property type="protein sequence ID" value="ROT64002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NQE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1058" mass="110780" checksum="84CE69B5FE9FA156" modified="2019-04-10" version="1">MWFLQHLHPSSPPFPSPPSLLASVSLPPSLLASVSSPPSLLASVSPRLPPSSLRFPRLSPSPFPPPPPFPLASLLPRLRFRLPRLPPSFSLPRLLASVPSPPSLLASVSLASLPPRLRFPRLPPSSPSFSSPPPSSPPFLLPPSLASRFPCLPPPSPPFPSPSLPPRLRFLAPSLLASVSFPPSLLASVFPLPPPPSPPFPLFIPSSPRFLASLPPRLPFPFPPSSSPSVRFPCLPPSSPPFPCLHPSSPPFPCLLPPPPRASVPSLPPPSSLPPRLRFLASLPPRLRFPCLPPSSPPFPLPPSLLASVSLPPSLLASVSFASLPPRLRFPCLPSPPRLRFPFSFPLASLLARLRFPCPPSLLASVPLPPSLLALPFPCLPPSSPPFPLPPSLLASVPCLPPPRLRFRLPPPPPFPPSPCLASGFRPCLPPSSASVSLASLPPRPVSLASLLLASVFPPRLRFPCLPPSSPPLLPPSSPPFPLPPSLLASVSPLPPSLLGLRFPFPSLLASVSLASPPFPSALRFPFPSSPPFPLPPSLLALRFPCLPPSSPPFPPSLLLASVSLLVPSLVPPSLLASPCLPPSLASLLASVSLASLLPRLRSPLLPPRLRFSPPPSSPPFPCLPPSSPPFPLPPLSSLRFPSVSLAFPSSLPRLRFPCLPPSSPPFLASSLPCPSSPPFPSPPSFLASVSLPPSSSPPPCSPSPPRLRFPLPPSLLASVSPCLLLALRFLASLPPRLRFPCLPPSSPFPRLPPSLASVPFASLPPRSISLASLPPLPPFPLPPALLAFSLASPPSSPPFPCLPPSSPPFSLPSLPSSAPSSSSPRFPLPPSLLASVSPSPPLLPPPFPLPPSLLASVASSAPSSPRLRFPCLPPSSPPFPCLPTSSPPFPFPPSLLASVSLASLPPRLCFPCLPSLLTSVSLASLPPRLRFPCLPPSSPPSLLASVSLPPSPPRLRFASSLLASVSLASLLPRLRFPCLPPSLLASVSLASLPPRLRSLASLPPSPPFPLPPSFLASVSLASLPRLRFPCLPPSSPPSLLAGERRRPGGPARAERPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NX73</accession>
    <name>A0A3R7NX73_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">OTU domain-containing protein 3</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_012575</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Deubiquitinating enzyme that hydrolyzes 'Lys-6'- and 'Lys-11'-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains. Important regulator of energy metabolism. Glucose and fatty acids trigger its nuclear translocation by CBP-dependent acetylation. In the nucleus, deubiquitinates and stabilizes the nuclear receptor PPARD regulating the expression of various genes involved in glucose and lipid metabolism and oxidative phosphorylation. Also acts as a negative regulator of the ribosome quality control (RQC) by mediating deubiquitination of 40S ribosomal proteins RPS10/eS10 and RPS20/uS10, thereby antagonizing ZNF598-mediated 40S ubiquitination.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002593">
        <property type="protein sequence ID" value="ROT69259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NX73"/>
    <dbReference type="STRING" id="6689.A0A3R7NX73"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22770">
        <property type="entry name" value="OTU_OTUD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.80:FF:000005">
        <property type="entry name" value="OTU domain-containing protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF7">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0007">Acetylation</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="16">
        <location>
            <begin position="50"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="188"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="298"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00074859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT69259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="406" mass="45870" checksum="644267F6DCB8B87B" modified="2019-04-10" version="1">MIEAEVEMARKREERAIRNAQRAARKARASQSGQDPSFVSLKQQLVAMGLTLREIPGDGNCLFRALGDQLDGTPNTHQKHRQDVVAYMRQHRSDFEPFVEDDVPFDRHLSNLAELGTYAGNDCIVAFARLHEVNIVIHQLNAPLWQISGIEGKKNIRELHISYHNGDHYNSVRRIGDVTTSPASIKLAVQESSNDTKDKKKNGSKSPEKSYSDDYCQEYGQEYGQDYPVWSGEGYDYSEPVYEGLSKEEQMVIDKTGCEDLQLIRFQLEAHEYDVEEAIESTLNYVFSQQKGENPQITLSTNGIWGPNGTGTRIFGEGAATPIAPPTSIHPSYQKKTAQEKLQQRLRTQPHLSNSKRKELKKQLRKQQANDRKRQQQASYDSDDPTSNPSDDSEVIIVKDIGCLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P004</accession>
    <name>A0A3R7P004_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002283">
        <property type="protein sequence ID" value="ROT71529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P004"/>
    <dbReference type="STRING" id="6689.A0A3R7P004"/>
    <dbReference type="OrthoDB" id="308690at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT71529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="454" mass="51012" checksum="DC8371AC233EAA69" modified="2019-04-10" version="1">MNFAEVLRTSGGLLSWSPSGRFCAVPITARLEIRDSSTLQILVTYNCIDAIQVIEWSPDSNYVLTANYKRNIAEVWSIEDPDWRCKVDEGSAGLIRVIWAPDSRHILTTAEFHLRITVWSLVSKSVSYIKNPKNIPGGLQFSQDKEYLAVAERRDCKDYLSVLETKSWQLVKHFELATRDIAGLQWANDSSVLVVWESPLEYRVLIYSLSGQCLANYSAYQWSLGIKSIAWSPSGQFLAIGSYDQKVRLMNHITWRIISEFCHSSTIDSENCVIYKEVEKPLTGYPATLASVQGLPLVLETTYEEEESRPVSLASITVEPGKQANPRIGVGTLLFSSDNRYLATRNDNMPATVWIWSIPKLALKAILVHANPIKDMAWDSQHPRLALCTGNSHVYFWSPFGCLTVAVPGAPTLQINSLRWHPSGSRVALIGRDQFSVCFFDKQLQLCESISSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P483</accession>
    <name>A0A3R7P483_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_006488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT75004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P483"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="504"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="612"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="642"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="679" mass="73028" checksum="3BD88F790E1F4533" modified="2019-04-10" version="1">MAVASFPLVLPLSLFSSRRSLLSRWLFAVGSFSLVLRLSSLSRSPLSLCLALVLASSPLSSRGHFASLSRRSFLSLSAIRSQPTSSSLPPTRSRILPSLLLALAFSSLFAFALPLSRLASRSPPLPSLVPLSSALSSPAYFSDRMCAPPLSSLALALPLSGLFLTFSLSPLSFVLGSLLFLSLILCPQPHWPWALAPVAISASSPLFSLSLLALPSSPSLGPSADRAAIRRVSPLIRLFAHPSLSHLSISSSPRSRVHPLLSLALALPSCPLASIASSLTPPSPSAPLVSLLPCPRCYPAHLLFSLLSRCSLSSLGSFRIPLLHASVASPSPLSLLAVPRLSRRLPLPFLRSPLVPRLSRALFMILSASITSLLSRRPSLIGPHLCSPSLSWPSLPAPPSLLSIASQHVPSLLSPLPSLSLPPFPPLSRLFLSSPRLSSSSPVATSLRRRSHPLSRSHLSSPLSPHLLSLSLPLSRNGVLEAREFRSVMNDSEGWDIGRKGGALLSLVPLWSPFLFPLPFLLLHLSLLFSHPLTPFALCHFLILLSPSFSPPSLLFFLPPSLPPFSSSLLFFFSLFFSSLALYPSCSQYPSLPLLVLSPFQVLLPSSPSPSFLISSPFLFSSIPLSQFSSFPLYLSSFFSVYFFFLSISLSFFCLFSLPLFVLPPFPMLFPSSLSPPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P9P9</accession>
    <name>A0A3R7P9P9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017337</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003201">
        <property type="protein sequence ID" value="ROT64706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P9P9"/>
    <dbReference type="STRING" id="6689.A0A3R7P9P9"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF11">
        <property type="entry name" value="SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="5"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="164" mass="17350" checksum="DA087B8FF3FA7D10" modified="2019-04-10" version="1">MSSKILNFNVGVLGHVDSGKTSLAKALSTVASTACFDKNPQSKERGITIDLGFSSFLVDPSDGIRDAGYEKTQFTLVDCPGHASLIRTIIGGAQIIDAMMLVVDVTKGMQTQTAECLVIEKQKAGIEKMTKKILLTLQQTKFANAKVIAVAAKPGGPEAPDVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCJ5</accession>
    <name>A0A3R7PCJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vitellogenin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_020750</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004146">
        <property type="protein sequence ID" value="ROT61461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PCJ5"/>
    <dbReference type="OrthoDB" id="6484170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045735">
        <property type="term" value="F:nutrient reservoir activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.50.20:FF:000007">
        <property type="entry name" value="von Willebrand factor type D domaincontaining protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.230.10">
        <property type="entry name" value="Lipovitellin, beta-sheet shell regions, chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.80.10">
        <property type="entry name" value="Lipovitellin-phosvitin complex, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.50.20">
        <property type="entry name" value="Lipovitellin. Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.20">
        <property type="entry name" value="Vitellinogen, superhelical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015819">
        <property type="entry name" value="Lipid_transp_b-sht_shell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011030">
        <property type="entry name" value="Lipovitellin_superhlx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015816">
        <property type="entry name" value="Vitellinogen_b-sht_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015255">
        <property type="entry name" value="Vitellinogen_open_b-sht"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015817">
        <property type="entry name" value="Vitellinogen_open_b-sht_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050733">
        <property type="entry name" value="Vitellogenin/Apolipophorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001747">
        <property type="entry name" value="Vitellogenin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345:SF36">
        <property type="entry name" value="APOLIPOPHORINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23345">
        <property type="entry name" value="VITELLOGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09172">
        <property type="entry name" value="Vit_open_b-sht"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01347">
        <property type="entry name" value="Vitellogenin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01169">
        <property type="entry name" value="DUF1943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00638">
        <property type="entry name" value="LPD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56968">
        <property type="entry name" value="Lipovitellin-phosvitin complex, beta-sheet shell regions"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48431">
        <property type="entry name" value="Lipovitellin-phosvitin complex, superhelical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51211">
        <property type="entry name" value="VITELLOGENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vitellogenin" evidence="9">
        <location>
            <begin position="67"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2396"/>
            <end position="2417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="2407"/>
            <end position="2417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT61461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2417" mass="266125" checksum="94EAE2867AAF0910" modified="2019-04-10" version="1">MQTSLKTLEEVTLRSRSAGDGDGYIRPRRRGSSWFALVAGSLAAPWGADVPRCSTECPVTGSPKLAYQPDKTYAYQYSGKSKVQLKGVDNGDSETEWTAQVDLTWISPCDMAISFKNTKVDGTPGPIVARTLERHPLVVAVVDGRVQHVCAHPEDEPWAINLKKGVASAFQNSIPSLSAVSSGITVTEERKSLSSRRRTTATVNNVTHTRSYTCTMAEGSPANPGIHVTVQAGNRQWHLHRHHVSGQEHRSTCHWNLQVRGASQDSTLRFISESSDTSAISAIPSGEMQVESLLYNHQTMKDPQLAPELDELMKGICDKTKDTVEAEAAALVAKALHLLRRVPETVVVETAQKVRQGHYCSDSARLESIFLDAVAFLHESGAVKVMVQEIENGRATGGRLALYTAALYLIPRPSIEAVKALTPLFESPRPVPSVLLAAASMINHYCLHTPACHQKAPVARIAEILATRVQSHCSPSAGAEGEEVPLAFFKAIGNMGVATPAVTRAAVQCIEEEGLETSIRVAAAQAFRQANCFRPAVEKLVDIAVRPAFDTEVRIASYLAAVRCAEQEHLEKIIEKISKEENTQVRGFVLGHLINIQEGSCPNKENLRYLLANVVIPTDFEKDFRKFSRHIDMAYYAPAFGMGAGLESNIIYAPGSFIPRAVNLNMRATVDETPMDIAEIGARFEGVDSIIEELLGPQGYLRKATFGKIMEDITGFAGEKGLKIMEHFKHTMRTRRSIDASVISDFFGKLYGESSSHTHADIFARFMGHEITFADVAQSLKGVTADTLIETFFSFFENSLEHMKDLNLNTARTAQLSMDYSLPTIQGTPLKLNLAATAVAGLKMEGNVNIGQILSDLGNSHTGIKVFPGLSVQATGFVGFECRFTKVGIEMQNTISSATGAAINIRTTENKKIELELEIPDKMELLNIKAETYLVKARGKKMTKISPSSMRDVRIERKSCIAALEPVFGLKVCYDMNFPDVFRANALPLGEPAIAKLYVEKADPSMRGYLVTAAIKNKRGNKLIKMNVEAAGASTPRRAEMTLSYTKEEGSHIVSAKLDSSSIAAGVWTTLTNEQGHKAVETYVNFKYGQTAISRGIKLEAIAREGSVGEEFQVNVFSSGTRSFPLDSHIVEAKFIKKTSGPEFNVDVICMTKNALADYFDLNIEVGADFMRFSPKALYSTRYIPKTRIFLPVNLRKLEINAATAAWKVTSYIREGSQSGESREFSSAFKLAKGRTDVIFVQATHTIEGRFPQNVIIKNVATAKVGRSSYRAMYDVFYHPEKVGASIEVLQAAGNEKVAQIEAIYEISGEKHCAKFLAAIPGYIQPVKVEAEIEQEAEGRYALEAAIKYGPRTVLGVSGPVLARFTSKAKLQANIKLRAMASEPYIIGANVVFGNKKQMIAMEIKERSEPLIGLEWRMVRESSEKTTIGVVFVLPALIEQKVDAEITDELVHVSFNNLVLPKTSSRRRVKGFADVNIAEKRANVEFSWDADNAPEKKLVLDASLISSPANPGHAEIHGNVVIAGEPYHAKLVLTATNLVEHMEGENGFKLILTTPSQKTVVVGASCDVQLAGATTKVISTVEYKNVRDRKYKYTSVIALERLGGPLNYAVEAKVTYKQPGTAEIKVETTAKHHWTPEEHVVAFKVAAEAPVLKTPAMIAFSIHNAPNAFVGVCKIERTAPFTAFEWNVQVTPEGGIEAVEAGVDMKAIIEVLKIVRAIATLEEESYETYGPHTAQYQYRFTRPSPTSYTMQMRTPTRTMEGRAKLSPRESGIKFYPNKGKTESKYEIGYKVNHEGRWAQRASKLEVRMNHPVLPKPIMAAAQYTVAEGTMRGTIELDIFPEEADKITGTVETQRISENAIRAEAFLTGRMLKVNPKAIITAAYAPETVALDVVFHKTPSAAPIFAIAAKYDKTAAHSAAATLTVKMEERPVFEMSAVTEPEEAATCNGIRMNAVAYAAAFGKYNVFSKMCRPAFIEVTAMRPGGAKEYTAKLGLRYPDAAEAGVYVASAGESRGVAVAAVKLASPTMLQFEVAHEPEEAHIVMSEVTSTLRKVAMSLETVAMEAVQFLKEEAAAKGVEFPSSHFVSLVDEANEEIKAIYRDIVSEMRILDTELIADILESPTVSFVSRVYLGVWSQIARLQHHFSTRAVEMIQQWQEQLTDVSEIFIEAVMEIVQLLEAGEVPETVRVILEKIENTEVFRIVKREVNAVLAEYPEEYEAVKHILTRVTATLKHDADIVYKRIMETPAVQRIFAYVMQYINSERVFAEEAGSVASLILKEFLFVSIESEGNGIAVRIPLHRPLYSLTQVAQEAVPNPVTMLENLIFAYLEYIPIPVSDAIWAYYNFLPRYITDALRPTHEQPWWLAALRSSASAALLCEHLARPASFSWLLTAPTASSCPTRKPQPRHSLSSRHQQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEB6</accession>
    <name>A0A3R7PEB6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein RACK1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_019142</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003510">
        <property type="protein sequence ID" value="ROT62986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEB6"/>
    <dbReference type="SMR" id="A0A3R7PEB6"/>
    <dbReference type="STRING" id="6689.A0A3R7PEB6"/>
    <dbReference type="OrthoDB" id="7875889at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045182">
        <property type="term" value="F:translation regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001252">
        <property type="entry name" value="Receptor of activated protein C kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="RACK1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="11"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="59"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="144"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="229"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="288"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="318" mass="35644" checksum="DB86403A2C2A60D1" modified="2019-04-10" version="1">MNESLQLRGTLVGHNGWVTQIATNRNFPDMILSASRDKSLILWKLTREENNYGVPQKRLHGHSHFITDVVLSLDGHFALSGSWDKTLRLWDLAAGKTTRRFEDHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAQCKYTIQEDGHSDWVSCVRFSPSNSNPIIVSCGWDKAVKVWSLTNCKLKTNHYGHTGYLNTVTVSPDGSLCASGGKDAKAMLWDLNDDKHLYTLDHTDIINSLCFSPNRYWLCAATGPSIKIWDLEGKNMVDELKPDVITQNPKAEPPQCLSMAWSADGQTLFAGYSDSKIRVWQVSVTSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEM2</accession>
    <name>A0A3R7PEM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002657">
        <property type="protein sequence ID" value="ROT68556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEM2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="47271" checksum="AD4862D3649C4FD9" modified="2019-04-10" version="1">MTDQRRCDTDQHSQPEINTPPPPHIHNSQSHPPPPPSPPHTTQTLNPTLSPLPPTTLNHIPSPLLTSITPNPTLPLLPPLPHHKSQPHPSPLPPKLLTPSLAPPPHIHNSNPTPPPPPSPSHTHTLKPHPTPSSSPPSFPSPFSHNFQSYPFPFPSLPQFSTLSPPLPPNSHTSPAPPPPSHLFPSPFPPPQLSSQPSLTPPQLSTPSHPLLTPIPSSHPHNSHLLPLPHTPTTFNPTPPSLLTPSLPLPPSLPPQTFNPTPSFLPPTILNLPSPPKLSSSPFPSPLLTLPFPLPPPQTSSQPLPHTPQLSTLPFPSLLTPQLSTPPSPPPPSTTPNPTPPLLHNSHPSPSPLPTTTLILPPSPTLSHPVLLTPSPPLPHTPTTFNTTLPPPITLILITPPSPPLPFPHSPSPPTNNTTTGRQDALTRSRFLIRNFRGDGAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJC8</accession>
    <name>A0A3R7PJC8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C20G8.02-like WWE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013417</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002666">
        <property type="protein sequence ID" value="ROT68427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJC8"/>
    <dbReference type="STRING" id="6689.A0A3R7PJC8"/>
    <dbReference type="OrthoDB" id="69269at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057826">
        <property type="entry name" value="WWE_C20G8.02"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF48">
        <property type="entry name" value="INTRACELLULAR PHOSPHOLIPASE A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23463">
        <property type="entry name" value="WWE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C20G8.02-like WWE" evidence="2">
        <location>
            <begin position="406"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="740"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="778" mass="85201" checksum="8E3565AB00A0E9BF" modified="2019-04-10" version="1">MDFSGGGGQHLGGQHLGQHLGQHLDYGHGLSQQLGQLTLDHSSRPPLCPSAGTRTSFGGEVLPRDTGCASDISFGRSFSPAAFQSATSQLHETHSQLQQPYLQQREQVSYSSSPLSSSNPSLLGGSPVPTQHQLSPSNLGTLGLQSPRLTPIQSQTSSPIRSSLGTAQLSSSSMTAGIQKDTLAPDTQGFVGHMGGSHSPVHSQLGRAQLASSLPTSLQPRPFQPQHTPQNRLSGAQLGSSWGSVDSQSASYQVPLQPGSNENSQGSGLGYSNLSTYNTHVVNGQMAAGMHLQQDMQYQNQLQFDSMGFMSMQSQQMQYGGFTQLQQTFPQETNGFQYNVDYIDSADPNAYQDYYYDYQYNSYNGSMDSLDPNYLGTPVGRAPTPYGDETVDDLGPEEVRWFYKIEADKKWTPFIGYDSLRIEWKYRDLMQDTNPGGSNGSPYGNVENEQQSPKEMQEKSQVTERIVVRGGLYEVDVKHRRCESIYWKGEVFMICRGTWFYEGAWGPVEEMLADRLEMEHLTHFRGHLLTSQRVDDTTKEIVHSLSLPEGQVDWFSASEIYLSSDATPSRLMRSVGKKLGFQKTGYKLHRGYSIDATASDKPPDISHIVFVIHAWGSGRAEGEMMGVGGIYHLPPSTPRPPLQNPIGGNTASILHANNINNLINKLSFCIDMSTGSNIVSPLQRATSRDLYPEGDSRSPGQISCRRRQRRRPAAASRSGQGGLRGGRVTALSSLAGGAGHPHERRGLPWRERHRHSSQGPRRAPGGAPSGTPGWRSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PMM1</accession>
    <name>A0A3R7PMM1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002299">
        <property type="protein sequence ID" value="ROT71435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PMM1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="537" mass="58500" checksum="D948F3812D214C5C" modified="2019-04-10" version="1">MLQLGSDAARAPVREARTEKVGGFPSSLVPVLFPHSPCAASTCCVSSRHSALAQRLREGSWKALVHTQRQLSLGGGKSAFVRCVCSWMSAVSQRHVSYQQKGRRVMLPRRFRWMTHRSPCVARLAFACSARGRLGSASQRRMKTVISSPVRPPGPSPPSAHVPPERRVRPERLPQQTSQPVGLPGSGAIDRRPGRESVIEFTSRFLWRPGFIPCHSASLWTFGRLIDPADLGIRSRRSQSTLSRHVSRSTINLNCSAGGRVACGKGLRESEASSPSCSVTRIPAALPLPLFCSESPLVVSEDQPGGRSALLPVRVCLQHRRAVRACPVPAEGRLQARVARAWQLFHTADHWSRKVTVRSLADEELKSPAPSACCSIFLARLLCGRVPSGFPRAPRGPQEPQEEGKEQPRRQSPSLPRPSLGRADFVPSVIFSSRPLVPPRSVRAAGETLGRLGWSVKTIRGLVKCTPWLARRTAKAGQRPRRATGGTGVQARVGFNIGSRDPAAGYRTSSSTKSEKSVSTRSGFESARYSPFSFLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRV1</accession>
    <name>A0A3R7PRV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="28">Putative src substrate cortactin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">C7M84_000656</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="28 29" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell junction</location>
            <location evidence="4">Focal adhesion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell projection</location>
            <location evidence="5">Dendrite</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cell projection</location>
            <location evidence="9">Dendritic spine</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell projection</location>
            <location evidence="7">Lamellipodium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell projection</location>
            <location evidence="6">Ruffle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
            <location evidence="8">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Membrane</location>
            <location evidence="10">Clathrin-coated pit</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001100">
        <property type="protein sequence ID" value="ROT80611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRV1"/>
    <dbReference type="STRING" id="6689.A0A3R7PRV1"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043197">
        <property type="term" value="C:dendritic spine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005925">
        <property type="term" value="C:focal adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030027">
        <property type="term" value="C:lamellipodium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001726">
        <property type="term" value="C:ruffle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11959">
        <property type="entry name" value="SH3_Cortactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000087">
        <property type="entry name" value="Src substrate cortactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035716">
        <property type="entry name" value="Cortactin_SH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF23">
        <property type="entry name" value="CORTACTIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="18" id="KW-0965">Cell junction</keyword>
    <keyword evidence="12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="24" id="KW-0966">Cell projection</keyword>
    <keyword evidence="22" id="KW-0168">Coated pit</keyword>
    <keyword evidence="20 26" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="23" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="15" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="17" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="21" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 25" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="19" id="KW-0770">Synapse</keyword>
    <feature type="domain" description="SH3" evidence="27">
        <location>
            <begin position="50"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="26">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="28">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00004552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00004600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="ROT80611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="12419" checksum="AED507FE862E0B03" modified="2019-04-10" version="1" fragment="single">AEREAAEEAAARAEKERLEAEVRRQEQLLMGNPQIPAAEVADAPEAQDEGMGITAFALYDYQAADTDEISFDPDDIITNIEMIDEGWWRGWCNGQYGLFPANYVQVHSPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWV8</accession>
    <name>A0A3R7PWV8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000344">
        <property type="protein sequence ID" value="ROT85258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWV8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="42037" checksum="7B3C5F49C5330FB6" modified="2019-04-10" version="1">MACSGVTESAGSLSLLILWHSAPMSISPSFLSFSPFLLLHESVTDYFPDIAEGSSTLGREARALLASISGALGPATPPSELSQHPGHFCNGLNIFRGGPSMRRRGGARSGKRNISTNSSFPSTLHALSLLISLLRYPLVFFPLLLLLSPRFVCLVNPFFFFSHCPPPSVVFSFLFLFNLFPFSPSLLPPSINPFPSNHPSSLFSFPSSPLSPLIPSLFFLIPLSSLYSFLSLSSLIPFSIFLSILSPSLYSFPSPLSPLSILSPFPSSFSLLSPISPSSHILSIHPSLPSSLPLFSSLPPCAAVWRTLPMLCSLKTYGLLDLLKLPPESAFDFQCKGLAGLGSLWPTLDLSLNGPHGHRLLPHTNYNTHTSADKSIAAGAENHAAASDFQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYU7</accession>
    <name>A0A3R7PYU7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Medium-chain acyl-CoA ligase ACSF2, mitochondrial</fullName>
            <ecNumber evidence="4">6.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_025454</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a medium-chain fatty acid + ATP + CoA = a medium-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:48340"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:59558"/>
            <dbReference type="ChEBI" id="CHEBI:90546"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>octanoate + ATP + CoA = octanoyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33631"/>
            <dbReference type="ChEBI" id="CHEBI:25646"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57386"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.2" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000984">
        <property type="protein sequence ID" value="ROT81392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYU7"/>
    <dbReference type="STRING" id="6689.A0A3R7PYU7"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF5">
        <property type="entry name" value="MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="64"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="9">
        <location>
            <begin position="544"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="621" mass="69057" checksum="54DC5731C18CD31D" modified="2019-04-10" version="1">MNHSATYILASQRRVFSHFLHRRRQPSIPGTWKRWLSGAPFEWSYVSTPSSEPLLGLSIGQVVDRAERRFGDREAVVSVHQAVRRTFSQVKEESDLVAAGFLAAGLEPGDRLGIWGPNSYEWYLTQFAAAKAGLILVNINPAYRPNELEYCLNKVGVKGIVCDEKFKTSDYYKMLCAVAPELPSSAPGDLSSSAVPYLKKVFMCSQEKLSGTFRFQDLYGAGESSHRKRVDELSSKIQFDSACNIQFTSGTTGLPKGAVLSHHMLVNNAYSIGGRTEYQKKPHRICISVPLYHCFGCIGGTLCGMLYGATSVLPSAGFDPEAIVKTLESEKITSCYGTPTMFVDILNAYRKNPTDLSAISTGIMAGAPCPQELVMAVMNDLKMKDFLVMYGMTETSPVTFQCFPSDPPEVRSSTIGYPGDHIEVKVKVDESGAIVRAGEAGELLVRGYCNFLGYWDDPGKTREIVTEDRWLRTGDLALIQPDGYGRIIGASRTWSSARREHLPGGGRELLHGSPGRDRGGSHYYQKFSCNFLPITLENLLRTQVFGVPDARMGEEVATWIRKAEDSSLSDAELREWCKGKIAHYKVPRYVLFKDEFPRTVTGKIQKFKMRELTIEELNLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PZS1</accession>
    <name>A0A3R7PZS1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative late histone H1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_017241</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003180">
        <property type="protein sequence ID" value="ROT64816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PZS1"/>
    <dbReference type="OrthoDB" id="10070354at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000140">
        <property type="entry name" value="Histone H1.0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF36">
        <property type="entry name" value="HISTONE 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="9">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT64816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="18077" checksum="9FCFDB879D69D8C4" modified="2019-04-10" version="1">MAETAAVKKAPAKKPTHPQYAIMIAAAIKALKERTGSSRQAILKYIIANYKVGDEKKAGVRLKLALRKGVTKGTLRQMKGTGAAGSFRLAKDEAKPAKKAAKKPAAKKPAAKKPAAKKPAAKKAAKKPAAKKSPKKPAAKKVAKKPAAKKPAAKKPAAKKVAKKPAAKKPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q0S2</accession>
    <name>A0A3R7Q0S2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000752">
        <property type="protein sequence ID" value="ROT83006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q0S2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="606" mass="65443" checksum="0DD82304F8021290" modified="2019-04-10" version="1">MIKAHQLLPSSLPLFPYLLFSTPSFFHTFHLFSTPSFHSHTFHLPLLHFFLLSSTPSTYTASPLLPSSLPHLPPTASPPFFLSSTPSTYASSLPLFHRLLHSSFFFHTSTYRSPLLPSSLPTFHLPYSFLSSTPSTYRFSTSFFLSSTPSTYRFSSPLLPIFHTFHLPLLHSFLSSTPSTYRFLHSFLPLFHTFHLPLLSPLLPSFHTFHLPLLFSTSFFSTPSTLPLLHSSSSLPFPLPLLFSLLSSTPSTYRFSSPLLPSSLPHLPPTASFPSSLPHLPPTASPLLPSSLPHLPPTASPLLPSSLPHLPPTASPLLPSSLPHLPPTASPLLPSSLLPLPLSFLLSSTPSTTASSLLSSSLPHLPPTASPLLSSSLPHLPPTASPLLPSSLPHLPPTASPLLPSSLPHLPPTASHSFLPLFHTFHPTASPLLPSSLPHLPPTASLLTLPSSLPHLPPTALSTPSFLSSTPSTSSPLLLLSSTPSTYRFSTSSSSLPHLPPTASPLLLPLFHTFHLPLSPLLPSSLPHLPPTALLHSFLPLLPHLPYRFSTPSFLSSTPSTYRFSTPPSPSCPSSRDAPTAPLHIREQRKTTSLSPSSFTPLVRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q367</accession>
    <name>A0A3R7Q367_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000490">
        <property type="protein sequence ID" value="ROT84836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q367"/>
    <dbReference type="STRING" id="6689.A0A3R7Q367"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="297"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="42822" checksum="6A05ECB9485AA4B0" modified="2019-04-10" version="1">MTHAYTADKTNAKTRKQLIPRCLLCPVSLLLCFFNSLPLLFFLPSPPPSPSSSSFPHTVQISPPSPHHLTLLPSHITLSPNYPPPPPTTYPLPTPLPHILPSPPNPPHHLYPSHFLLPHTTFSSSSSFPPHHRALPFLPSPTPPYPLPPLLHPHHPTLPHPSTSPTPPTLHTPSYHPHYLRYLPHLFSTPPYPLPPPPHHPHHPTLAIPTFPTPPSLPPNHPHPTSPPNPSFPPHQPSHPTLIPHPTSQSLLSPHHPTLHPTLIPPPPLPSNPSFPHTTHPLPPPPPHHPHHPTLPTPSHTTLPSHPTLPHHPPLPSLLPPHHPNLFLLLPPHTTPPSLQTSFPHTTLPLPPTLLPPTPPYPPTPPPHPPSHPPPPSPAPSQRRASRCPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4T3</accession>
    <name>A0A3R7Q4T3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002655">
        <property type="protein sequence ID" value="ROT68577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4T3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="485"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="72169" checksum="04CAED8B05682A92" modified="2019-04-10" version="1">MSPSQQLTPSEAAKPHPSIPLQNPFSSFPSPDPRHPKTRTFPSLFNPLTLPHFSTLLPYASRTPHSEHLSSPSTSSDISAPGLQSTSSHLTALQRLIFLPCQFPASRTPHSEHLSFLVSGAPHFPKISALQRLIFLPCQLPGLQIIFRRSQLPCTSSDHLSSLASKAPHLPSISPSWPPELLSSYQRLIFLPCQLPSLQSTSFSEHLTSLAPHLPAILAPWPPKHLIFLACQLSSLQSSSSHLSALQRLIFRPCQLPGLRSTSFSEHLISPAPHLNISAPQPPDYLISEHFSSPAPHLPSISPPQLQSSSPQLSSTSSPNHFSFPASRAPHPEHLSSLAPHLLIISAPWPPSTSFPSISALQRLISYHLSSTSSFDHVNFSASRAPHLSSPAPHLPSISPPQPPEHLISRTLSSPAARSPHLPSISPSGPPELLSSYQRSSSQHLSPGLQKHLHSSNTSASRPPDPHLTSQLSSTSSSLPCQLPGLQSTSSSCHLTSPASRAPHLPNNFSFPASKAPHLNSLAPHLPTISASQPPEHLISLSALQHLIFLASQLPNLQSTSTSALQHLIFLASHLPSLQSTSSPSISSLQALIQPPPASRHLTSPASRAPQSSEHLTSLAPHFPSISAPQPPEHLISRPLQLPGLQISSSGAPQLRRIRNREASDHTHIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q5H2</accession>
    <name>A0A3R7Q5H2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q5H2"/>
    <dbReference type="OrthoDB" id="5857140at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="718" mass="74193" checksum="792AF5A92CA83FAC" modified="2019-04-10" version="1">MVSVVGGLLSQSALRAVGGEERPQGPVSLFGKGQVGAHASWMQARLSKGVAAHWSKSEPAPTLVVGGPAILGQSGLSDSRSLGPTGPSDPKSHHASAPLLGTWACVGTFLEPRRRARNVLTVDRSATPKQVPVGVHVPSIGPGASAPPSCLSRVPTSTSAPCSAASGALTTSAPTSASPATTAALPATCMCSSRLVHNACEGASPPPDGNGPAAKGATNGPAHMTGSTRPGRAVARVPGITDASAPSGCVTPGPRGTRGNRRRPRRPKGAKSTGRYKSGAKGRSESGMVHRHPTGAETGLSVAPVTGEVSSSSRTLRFTDGAAAAGHVFLLTPGTCPETVMASDTGAPVRRNCAIQIPPTKRESDEMSNINYQLCRARSEWPLTPLSDTEVTRGRLASVARTCENEQQIPSFPRDGEPIPADRVICREDVAEAARGASAGGHVLGLTGRAGQASVGASVAASGSWMAELPPRRAPSPQCPAPLRASHPCHDSAWTAASCHVSVMNSLAPEHSRVTAHDTPPDGHPPPPEPPPAVTTGGAGEGEKAAPLKAENAAKGHSHFMLGTTCGRGQWAPGLREDIRAFDIYKISGGVCETHVPPLPALPTQSDTDTDTDEGSLGQVPRALRKRKINAEMRDGVERKRCRESEDEEDEEDKLRLEGVTLLLPSPLQLHSDFNKPKLSADASVARTLSCPFLPQELCPPPSAPPSAPTIVPPQPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q7Z5</accession>
    <name>A0A3R7Q7Z5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002377">
        <property type="protein sequence ID" value="ROT70861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q7Z5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="29639" checksum="77D5C7617B082E1C" modified="2019-04-10" version="1">MVPDGLFSLAERRARTLCLTYTTSSQSASHTDTQRSNMLGCLYSVDGRNHIHICRASSTSFDNSALIHPPTSSTFIQPSHPPTPFNHFVHPFHISASFIHFIHLHHSFVSSTCFIHPLSSTYSIHPSHSFVSSTSIHLVHPTCFIHKLQTTFIHALQPSHSRTPFIYPFHPQSLHRSPRSPTLDSESESAVIFPSRTPSDEKHESGRVYETHVVARSSKNSTSLPGDRFDKCSHPEQHNLSCSSRLSSSSPEVLTRRPGLSLGTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q8C0</accession>
    <name>A0A3R7Q8C0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">5'-deoxynucleotidase HDDC2</fullName>
            <ecNumber evidence="8">3.1.3.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">HD domain-containing protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_010517</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="8"/>
    <dbReference type="EMBL" id="QCYY01002333">
        <property type="protein sequence ID" value="ROT71185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q8C0"/>
    <dbReference type="STRING" id="6689.A0A3R7Q8C0"/>
    <dbReference type="OrthoDB" id="10254258at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009159">
        <property type="term" value="P:deoxyribonucleoside monophosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000011">
        <property type="entry name" value="HD domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="14">
        <location>
            <begin position="34"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00015933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT71185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="22867" checksum="271261004CD1651F" modified="2019-04-10" version="1">MSLGSPKNCLEFFKTIGRLKHIKRTGWVRSDVNDPETISGHMYRMAMMSFLLDEEDNVNRDRVMRISLVHDMAESIVGDLTPHCGVSNEEKHEREVAAMEHFSKLVGEKAGNEMFNLFLEYEEQKTNEAIFVKDLDKFDMILQAFEYETDQKRLGSLEEFFKTTEGAFSHPKVKRWVEELYKQRAESLNASTAESDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q954</accession>
    <name>A0A3R7Q954_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">IFT140 first beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002266">
        <property type="protein sequence ID" value="ROT71675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q954"/>
    <dbReference type="STRING" id="6689.A0A3R7Q954"/>
    <dbReference type="OrthoDB" id="16717at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056154">
        <property type="entry name" value="Beta-prop_IFT140_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23383">
        <property type="entry name" value="Beta-prop_IFT140_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT140 first beta-propeller" evidence="2">
        <location>
            <begin position="12"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="54"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="151" mass="17314" checksum="5B126A0A42786B0D" modified="2019-04-10" version="1">MELASTKVLWVDITVKCPIFCLAWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSSVRTMVWSHNDQWMVTGDTGGFVKYWQTNMNNVKLFQAHKDPVRGLSFSPSDQKFATGSDDGTVRIWDFYRCYEEKVLRGKDMKNSCFSYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QB56</accession>
    <name>A0A3R7QB56_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative LIM domain transcription factor LMO4.2-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008158</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QB56"/>
    <dbReference type="STRING" id="6689.A0A3R7QB56"/>
    <dbReference type="OrthoDB" id="6352355at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09390">
        <property type="entry name" value="LIM2_dLMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000015">
        <property type="entry name" value="LIM domain only 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000016">
        <property type="entry name" value="LIM domain only 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050945">
        <property type="entry name" value="LMO_RBTN_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45787">
        <property type="entry name" value="LD11652P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45787:SF1">
        <property type="entry name" value="LIM ZINC-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="15"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="79"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="157" mass="18003" checksum="3A61397B143A9C88" modified="2019-04-10" version="1" fragment="single">MRMAAVEVGKTTGSHECGGCGKRINDRYLLKAVDLYWHEDCLKCGCCDCRLGEVGSTLYKKANLLLCKRDYLRLFGTTGHCAACNKVIPAFEMVMRAKTNVYHLECFACQQCNHRFCVGDRFYLCDNKILCEYDYEERMVFANMSYSSDSLAHIKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCI4</accession>
    <name>A0A3R7QCI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative glycerophosphocholine phosphodiesterase GPCPD1-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_007025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycerophosphoryl diester phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001891">
        <property type="protein sequence ID" value="ROT74455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCI4"/>
    <dbReference type="STRING" id="6689.A0A3R7QCI4"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047389">
        <property type="term" value="F:glycerophosphocholine phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08607">
        <property type="entry name" value="GDPD_GDE5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.190:FF:000032">
        <property type="entry name" value="Glycerophosphoryl diester phosphodiesterase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="4">
        <location>
            <begin position="234"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT74455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="558" mass="63950" checksum="3558B21C672A2AA7" modified="2019-04-10" version="1">MLPRRIPEGESNVSDPSIEKYGSYGGSERVESGWLTRDSVVQFRLCTSPLYNDPVMLFKRKYQDKKVRIKVTPKELHNNSPGDPHNGVPGSEESSDFDISNLQIDSKPIWPITEVAVMNEEECLFHPQPQFGVVCNTGEYIVFQCRMLNIETNAFLCDFYIEDGNEELPNYLGCSYILPSNLKENFGVATLPITSPKHTAIGQLTVHYMVVYPMPTRCDMSVSYARHWKDTWKGLEVGHRGAGNSYHSEPKSCANIRENTIASLKYAAEIGADMVEFDVQLSKDLVPVIYHDFHACIALKRKKEQDKTDLLEIPIKDLTISQLQALKVYHKTEKGLSRFSDEDFEDHQPFPTLQKALESVPYTCGFNVEVKWTMQMRDGTYELQHPFELNRFLDLIIETILEHSGKRKIIFSCFHPDICTMLRLKQNRYPVMFLTQGVSELWPPYEDQRTTTIRHAVLYSTNADILGINVHTEDLMRDPQQVQMALEHALIVFCWGDHNNNQENIKFLKSIGLHGIIYDKIDVYNTKVKKESVFLCEEREAGINSNGTTSDMQETNHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QE21</accession>
    <name>A0A3R7QE21_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Hexosyltransferase</fullName>
            <ecNumber evidence="17">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_017577</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Transfers N-acetylgalactosamine onto globotriaosylceramide. Plays a critical role in preimplantation stage embryonic development.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a globoside Gb4Cer (d18:1(4E)) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18259"/>
            <dbReference type="ChEBI" id="CHEBI:18313"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:67138"/>
            <dbReference type="EC" id="2.4.1.79"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:22253"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 17">Golgi apparatus membrane</location>
            <topology evidence="2 17">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the glycosyltransferase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="17"/>
    <dbReference type="EMBL" id="QCYY01003247">
        <property type="protein sequence ID" value="ROT64485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QE21"/>
    <dbReference type="STRING" id="6689.A0A3R7QE21"/>
    <dbReference type="OrthoDB" id="115198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047273">
        <property type="term" value="F:galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008499">
        <property type="term" value="F:N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000001">
        <property type="entry name" value="Hexosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002659">
        <property type="entry name" value="Glyco_trans_31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214">
        <property type="entry name" value="BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11214:SF153">
        <property type="entry name" value="UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01762">
        <property type="entry name" value="Galactosyl_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 17" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00045577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT64485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="240" mass="28214" checksum="179E0C6C9A155C04" modified="2019-04-10" version="1">MTRLLRSNKWGNATFFPYTRMKTMYLMASAESEQTQRILRRESDAFHDIIQLDFFDSYENLTLKTLAMLHWTKTFCPNAKWVFKSDTDVFVNSFAVAKYLRQTSSDFVCSVCRHCPVCRKGMDCLEKWWVSEADYANEYYPPYCHGSAYMIRTDIAMKIYERANKTHPLVIEDAYFTGVLTHGMNITYTDLSRKMFIRTTSRLPRGFVQGSSLMALHIDTFSRRSPKLWRQIVEYNTGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QGC7</accession>
    <name>A0A3R7QGC7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001447">
        <property type="protein sequence ID" value="ROT78025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QGC7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT78025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="41640" checksum="1FC08F2B67FA68BF" modified="2019-04-10" version="1">MERREELIWRRHITPTFPSPPFSSLLLFPLSPSFPPFSLLLSPPLPPSSLLLSPSFPPSPLLLSSLLPSLPLSSFLLPSPSPPFSFLSSILSPLSHFLSLPLSSFLLPFPPPSSLLLSPSFSLPLVPFPLLSLPLFPFSFSLLPFSSLSLHPLLPPFPSFPLSSSPPFSFLPPLPLIPSSSPSFLHPRSPAFSPSLSSMPLLLALLAVPHLLLSPSFPSILSPPFLLPLSFLLSSPPSPLLSLPLPSFSFPLPFSLHHPSFSSPIILPSLFSSSPPLPSIISLLPFSSSHPLFSNFPFSLPLSISSPSPSSPSSPPHSPFSPLSPLLPSSPLFLLPFPSLSSLLFSSPSPFLSSLPPFPPSPFLSPFFLHFTPPSPSPHHCQRSAELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJT6</accession>
    <name>A0A3R7QJT6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_000178</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001027">
        <property type="protein sequence ID" value="ROT81073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJT6"/>
    <dbReference type="OrthoDB" id="10018316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.160">
        <property type="entry name" value="Zinc finger FYVE domain-containing protein 21, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032031">
        <property type="entry name" value="ZFYVE21_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038632">
        <property type="entry name" value="ZFYVE21_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16696">
        <property type="entry name" value="ZFYVE21_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT81073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="238" mass="26601" checksum="C94544A32E380677" modified="2019-04-10" version="1">MAGVTNSGKRLVRSKSGLRIIPLKDTDRSPFELREPEWIPDKMSPTCMDCKEKFDFLKRRHHCRRCGRVCCATCCETRLALPRMCFLDPVRMCSPCAETTSKENQFYNKDLKTLITGAILSQSAQDQFDLESCLVQCRLSPDHRYLILSGSQVDNLTPLSIPMHRVTGLHVANRFQDSAGNFKVTGVTVQYTLAGEDEDEVSIAAPPDASPSAYDFLTALEKAVFMMQEARAVIGIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QQI3</accession>
    <name>A0A3R7QQI3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thrombospondin II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_006795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001859">
        <property type="protein sequence ID" value="ROT74691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QQI3"/>
    <dbReference type="OrthoDB" id="6376919at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24039:SF28">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24039">
        <property type="entry name" value="FIBRILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 7" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="6"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="47"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="88"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="129"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="170"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="456"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="610"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT74691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="71021" checksum="F2543372D5EFDBBD" modified="2019-04-10" version="1">MCPDETTDPCLANNGGCNANADCLTVNGAVSCTCRAGYSGDGYTCTDVDECAVANGGCSASASCTNSVGSYQCSCLAGYTGDGFTCIDVDECLVANGGCGANALCSNTPGSRDCACKSGFTGDGFTCSDIDECLVKNGGCDVNAVCQNTNGGRTCTCLPGFSGNGITCTDVDECLVANGGCDANARCSNTAGSRDCACKSGFTGDGLVCTDVDECLVANAILQAAVTAPVNLHRRCLVCTDVDECQRSGPNQTGDGLVAQITCSCLAGYTGNGQVCVVLKCPVGFAGEGADCALDSDVDGYPDTELSCSSKYCRKDNCINRPNSGQEDADGDKIGDACDDEADVAGTKAMVDQIEEQCAEQELQLSTFQKEQVLPTLEKIASLISSHAITITDLSDMLSNKLNELHSECEKSHQNQEKMASEFEKQMNTHLEAHAARTVACLDNANALRSNVDSKAELVASKISSLETQLEDLKQISKELTSSASAGLSNIISDLGTLKEETHTANDNVKTLVKSLGENSHSHITATHSLEKEAQSAMEKMVHELETNVQHMGEERCNLESLVAQYSAHASLSICENRNIAEKHIKAVETKSAQDISDHGAQIEMAVALTKDLDIKNQLLEDEVSKLEKECAQLQKECQHTSRTLQSWSEDHMDDLNVQEMQVNEFFTENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QSA2</accession>
    <name>A0A3R7QSA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001667">
        <property type="protein sequence ID" value="ROT76384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QSA2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="655"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="804" mass="83424" checksum="F9641F2CCB2775ED" modified="2019-04-10" version="1">MQRDGNLGNIIILCDPLPFLLSLLRFLTSSSLPPLLLPLPFLLLLSPLFFSFSHSPLSFFLYLLLFPSSSPSPSSLPSPPLPSSPPLPSSLSPFFPPLPSPPLLLPSPPLLSSPLLPLLSPPLPSLLSLPSPPPFPSLSPLPHLHSPLPSPPLLSLPSPPLLPLLHLLSPPSPPLPSPPSSLPSPSPSPIPFLPSPPLPSSALPLSTSYPFPFSTSPPPPPPLPPLLSPLPLPSPPPSPLLSPSPFPLLPPPLPPLLPFPSHLLFPSLPLLPPLRSSPSPLPRPSLPSISPSSPPSPPSPPLPSPSPLHLPFSPLPPPSSSPPFLLPSPLPSLLPFPPFSPPLPSPPLPPFSPSPTLPFPFSPPLPSPSPTSYQLPPLPLLHLLSPPLPPPSPPPPPPLHPPSPLLSPSPLPSLPSLSPPSPLPPILHLPPPIPPSLPSPPLPSPSPFPFSNSSPLPFPFSTSPSPSPPPIPFSPSPSPLLPSLPSPSLPFPSLLSLPPSPPPLLLSLPLVHLLSPSPSPPLPSLTLPPLPSPPLVHLLSPPPPLLSPPLPSPSPPPLSFPLSTSFPLPFPSPPLPYPSPLPLLPPFPPPLSPLPPSPSLLLPPLPSPPLPFPSLLSLPFSTSSPPPLPPLPFPLSLLSPFPPPPLPLPFSTSLPSPPLPSSPLPPPLPSLPSLPSPPSPPLPPPLPFSSPPFSPSPPPPFPSFPPLPSPPLLPSFPSPLPFPSLLSPSPLHLLSPSPLHLPSSPLPLPLLHLLFHLLSLPPLPSPAPAQVLTPVHCLSAERGSDWHSSPPLGTVSILAKLVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SPS5</accession>
    <name>A0A3R7SPS5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002487">
        <property type="protein sequence ID" value="ROT69968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SPS5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="450" mass="49422" checksum="8B3A180940058D2F" modified="2019-04-10" version="1">MVEPYTCPPNAADTRADNRHIINQLPKPLATEQRAAAATPSVHIPTPAGSGFSSSFTYEPHSSLFFLSSLLSFLYLTLPSRYTPLFISRSPPFLPLSPNNSSISQSLLSSSLSYIQSPLHLSPHQLNPTPFLSLPYTPILLTPFSAPHLLHSNPPQFPLSSRSFPLSSSLLLPSQTSPPHSSSLPHPAPPSTSPSLPPLPHNSRKARFSTARGAKSKHTDYVLQTTFISGPRWARNNMPYCLRCLSAFLAFSNFLNASLTPTYPPPTLLLPLPPPYRSLTSYPPTLLPLPSLTPYLSYPLPLYPYLHLLPLTSLPTTYTPYFSLPSLPPPPTNHYPLTHSHPQNTAIHRQPPTLKTPKPTPPITHPPPHLPPHQNPPTFPLPLPPSSLPHPLSHGTADKRQPKWSPKSLRSIGKMDVAFPQKIQSEESIHSEILLSDLASTNSVPRKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQS4</accession>
    <name>A0A3R7SQS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002346">
        <property type="protein sequence ID" value="ROT71072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQS4"/>
    <dbReference type="OrthoDB" id="6379858at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018591693" evidence="1">
        <location>
            <begin position="20"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="263" mass="29058" checksum="6D4196D47518526B" modified="2019-04-10" version="1">MTLLLSALALGAIFGSITPLHLDKECVAKREWRADWDWSDTSINVWVPKDSTELLNIRLGLNELHHADITFTRSSIVASVSKDLATDERGRSEDCPLEAGWRRVRLSLKADYELHLGDCNGTSPVSFPGDLLPELPTWVEVTGSNITVNCEMDLLAWRVSRTAVAVPLDHSEWHRISVYSVHEILPRFILENHKVELGLGSSGLSTLDFQRALPAFVLHNLSLACTLNSNYSSCAFTVSEVVSPNWNYSRSCPVAAGDASKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SU30</accession>
    <name>A0A3R7SU30_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001806">
        <property type="protein sequence ID" value="ROT75154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SU30"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="428" mass="45846" checksum="EC6289699B6FE17C" modified="2019-04-10" version="1">MDKEADGNSFCTASPPSPFPSPFSPLPLPFSSLPSHPPSPLSPLLPFLFPPLSFPSPLALSSLSFSSLSSFLLLHSTLHPSLFVPLLSPLISSLPSTPASSSPLVLRPRSLSPFPSPPALHLLPHFSLPPPLHVSPFSSPLPSPSSPLPSLSPLSSSLPYIFSSPFLSLLSLFLLHSSSPFTSPPSLVSFSSRPLLLPPSLSPLPLPRPSPHLLPLPSFSPFPLSLLLPSPHILSFPFTLTPLSCPSTSFALFSPLLSPASLSLLPSSLIPLLLLPSFAPILLRSPPSLPCYLLPSFIPLAPPLTFSLLLSLLAPHPSSPPPLLHLPLALSLRSDTIWATADCVATWYVCSVTLSQIYSSSERGVRVVRRFSHSSFSPPLRYCDVFDTRTSFSHFNPPLSFSFSVTSLLSRHFLPPSSVSPLISLSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWS2</accession>
    <name>A0A3R7SWS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001306">
        <property type="protein sequence ID" value="ROT78994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="827"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="965"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="863"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="895"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1214"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1229"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1307" mass="146224" checksum="8D1BE4BE71CBEA49" modified="2019-04-10" version="1">MSVPEIKVTDSPDNELMDYEEDATSHQSRRYSDVRRRSSSSSPHRPQFRQSIPDIQIQTVDTDDHQRVPEYETQEYSDNVFDDSQNEEFFSIDAEGRSRRKSHEETSSDSQGRYLTEILNTKSRRSFSDSSPERYGRRKSVAELTPEMKARISVFEEITDFQTDMAVPSHLTDVEVRRVNVEYGHDQDIEMSNDEVFSSSSKGSSRRSSTHGDGLERRKSIKDKILDIERRKSLRDESVDIPDEYLEVNPASGGKRPRPEEEMFLIERRRSTGGELLDIKRRKSTREDDLGNLERRKSKDESAERKLSRGEIQDINRRRSSTKGELQEKDRRMSKEEIMTSKRRRSTRAELQELERERLSKVEMQLKRRKSSHGSSHDADGSSRRESVNSEDPNIQAALKSQLGTLLLLPEAGNAEDLSHNFETFRETTEETITPAVMARSFSELEASEGVEDAELEEQYLRAISPYLKYRKSISELEPYMQFQDKASEMKPKIQAQLSVTSESHNGEEGSLTRQDTEMRKSSMNSEHNDVTSGSETESDLDVKWEVNETDNSQPVIDIVPGIGRRESSGSRTSRGDPELVNYQTVNANAGSGERVSRSNSLRRRSSIPVVDVDPELQARRSQRYLEIASQQTEGLSRDKVDGSGISSSDAISQNSSPDVEEPSSQMSNTKGRKPSSAPSEDQSVEISRNYLETNDKDDEIINTNPNNQSNLDIEWNFDKPVTVRRLSNIPLDEDEYMTNRSSGPKYLNVQSEEALGGSEITERRKSISDVFPEIDFRRSSSIGATLDTINGESEADIMQDEVSTTKNSSHSVAEVQSSVFSLPDLNTFMTAPRPEMNSENQRRRSSVSNLSHGGRSRKSSVSDHSPQARSRKSSQSNLSADMKNVSPETHSRKSSVSDQSAENQNLGGSVSPNVLSRRNSSLSPQRRRSTVGGEFLFTQPRKSIAELTPAMLAKISKFETVADDSPITAETQDPDFQTDKSPAMNMPDIQIQTPSSESDNEDEYGQDPSFSHGVAIHEESSDMDYHNIPRERARQLSIDEELMILERRLSQTGDFPVVGESTDFKRRRSAASETPDIKRRKSSISRSMGEEDDISTGEILHLEQRRLTRHEIPEVSDMESLGSDRRGSTLSNISTSVHRGSAVRNISDYERRGSAVSNISASERRGSAVSNISASERRGSTKSNIASERRGSSVSNISTSERRGSSVSNISASERRGSAVSNSERRGSSVSNISTSERRGSSVSNISASERRGSAVSNISTSERRGSVMHNISASERRGSAVSNISASERRGSTKSNIASERRGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SYJ2</accession>
    <name>A0A3R7SYJ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000954">
        <property type="protein sequence ID" value="ROT81555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SYJ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="568"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="592" mass="62158" checksum="1207DA1E68D7024C" modified="2019-04-10" version="1">MFCQPFPFSSPNPLPLAPLLMLSPLLSLSPSPSPLHSPSLSITPPSRISLSLSPSSSPSPFSPPLLFHLPLSLLLHLPLSSLLSILPLSLPLISPLFSSLSILPSLLPLHSLLHSPPSLSLSISPLSSPISILPFSSPLHLPPLSPSPFPLSLPPSLFSLSIIPSSPSLPSPSTPPSLPSPPPSHSLSPSLLSPLSLSSPPLFSLSLPLPSPPSPSPSLPPALSLSLLSPPPLSLSLLSPSLSFPSPPPLSLSPLPPPPSPHPPLSLPLPPPLPPLLLSSLSPPLSLPLPPSLSLFSLPPPLSLSPLLPPLSLSPSSPLSLSPSPPLSLSLPLPPSLSLPPPPSLSSPHSLSSFLSLFLLPFPLMRTLTADKIKTKSEKLSLLLSLIIAALSHFFRLIALIFCSSSFGTLPFSSPRPLNSRGLAELKVNPRVLTFDPLPINCVFDNSFARVGNHPPFTEGYIAPVAAASAALGNRGRGRSARASSSFLCALSLPFFQSVIPVHASYAQSPPSFLQPPITPLNSLPLLNPRYLPHSCHHQSNHPHSTGQTPIKPYFHLRLHPQYTAQSPPNTANNPCCTPPRSINALPPATPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S997</accession>
    <name>A0A423S997_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_021599</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004547">
        <property type="protein sequence ID" value="ROT60804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S997"/>
    <dbReference type="OrthoDB" id="6362807at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00637">
        <property type="entry name" value="7tm_classA_rhodopsin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24246:SF27">
        <property type="entry name" value="ADENOSINE RECEPTOR, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24246">
        <property type="entry name" value="OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="92"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT60804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="44937" checksum="E092BA45AE0B359F" modified="2019-05-08" version="1">MEFQQTLHNHSNGGSSSCFTTLPDSLWNNLQMRVMLNGTDFPHDWEDLWYYETKYSRETPIITWEQLSQDCQIEQIFLLVVAVLVTIITVIGNVFILMVIVSTGLVYQDTFLIRTALAIADLLLGLMPAALAVFDHMTLMSGTTTLAHLLPKTFWPGLAHESSAKMQLEFHLLRFERGGYPLACAIVLTLSMSFSMFILALLSIERLCVVFGKPLRRSSIVLGLALAFVVSLLISLMLNWCHDHRAFTGYFDPVTKLTLGLRRHDQQARENLTIHSAHRVPEMRRLTETLTYMVLLFTLSCVPCILDIATDLRWPVGHHLAWWTFMAGSSWNWALYTLRGEKFWRHAKGLFGDAAHAHRPHIRLKSRKTKILFSEANAQDSGQYNECMSASFSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SIJ5</accession>
    <name>A0A423SIJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_018035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003336">
        <property type="protein sequence ID" value="ROT64040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SIJ5"/>
    <dbReference type="STRING" id="6689.A0A423SIJ5"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="435" mass="48098" checksum="CFC84B73D95BE372" modified="2019-05-08" version="1" fragment="single">LPTPITRGSGLVGRLPHPSPTRRLAPIRSSFPPLAASPSELGMADPPKTNKPLGPPRSRGSRGVSRGGSRAATAASRMSRGSGSSGSSRKDSDTVDEDGTKTPKLNPPRKPTSRAYGSVRARIRVRGGRPMMQGFANVGSVFDEAKSEELHPQIIKMARRSGQLNLSNRGMHEVPDKVYHIHEMDADEAKKMMMGMSMDSTDDDRWWEQTDLTRLYLSSNCLSSISPKISNLMSLQVLDLSDNCLTSLPSTIGELTCLHRLNLSHNRLEELPAGLFLISDLRSLQLDHNQLSSLSNDLGNLTVLEYLDVSHNALTELPASIGYMQRLSKFNASNNKLQELPYEIGDCFGLNQLDLNQNELKGLPDSIGNLQKIEQLYLRYNSIQILPPLHNCASLKELHLGFNFIKEIEAEQLNHLTGISVLDFETIRLMICLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ38</accession>
    <name>A0A423SJ38_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_017785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003280">
        <property type="protein sequence ID" value="ROT64277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ38"/>
    <dbReference type="STRING" id="6689.A0A423SJ38"/>
    <dbReference type="OrthoDB" id="289247at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052110">
        <property type="entry name" value="MCFD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23104:SF17">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23104">
        <property type="entry name" value="MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT64277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="16339" checksum="9257D6473ECE0D69" modified="2019-05-08" version="1" fragment="single">QPQQAAQGHQPHQNQRVLHNPNLGKERDHIKEHLEVPIDTAGMSEQELQYHYFKMHDADNNNKLDGQELIKSLFHWHDSANHDPAKTASHPDAKLFTDDELVAMIDPILEQDDRNRDGYIDYPEFVQAQRNAAAAAASTGTNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ58</accession>
    <name>A0A423SJ58_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase H1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003274">
        <property type="protein sequence ID" value="ROT64308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ58"/>
    <dbReference type="STRING" id="6689.A0A423SJ58"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="66"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="24316" checksum="342A12D69E611E75" modified="2019-05-08" version="1">MGCVESKKVVENVSSSDIKTVCHLEDVFGDEKCRSEGLSETEVKCELRVDDGNNLAEKIKLERLNKSNKFKTKQGTFSKVVRVENRLTKQPYAIKIIESKEGREAFEAELAILRRVKCPYIIQLVEVFESVDKIYMVMELATGGDLFDKIMTKGPFSERDAVKVLKMVLEGVKYLHNLGITHRDLKPDNLLYYHPGTDSRLMITDFGLAHTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ63</accession>
    <name>A0A423SJ63_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003281">
        <property type="protein sequence ID" value="ROT64275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ63"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="558" mass="59698" checksum="6D9F1637D4BA9298" modified="2019-05-08" version="1">MSPPLHHTSLAGRLLPPASPYLPRLPRLLHHNRSRYGHTTSPRLPLSSHLDPSLPPHHTLPLAPPSITTPSPFLHPSLPRPPTRILLHAPCSDPLRPLSVPAYPPPFPPNTHNLLTGPLLTPSTLPRPSTPTLAHHPSPLPPLAPFPHITGIPHFNTACTLPHFPTPLSPPIHEITHSLPPRPVTHALSHPSLPPCHHLSSPSRRPPTGPPVPEEVYWTRGLFTSTRRVRRGSSRLPPSLISYPHTPPPSHLLPPSTPSLLPPTLPPSLSPLHPPSPPPLSPYPPPLLLSSSPPSLPPPPSPPTLTPLLLSSFSTLLPSKHTLSLLPSHPPLLSSLPHPPFHPSLLPLHPSLLSLSTSILHPLSPTLHPPSLSLSTTPSSTPSILTIHPPLTLISLHQPSSLPPPLSYPPTLPPLSLHPTASLPPPLSYPPILTHPPSPSLLAPLSLHPPSLHNLTLLLSLSPPSLPSTPLSYHILHPSPLLSAPTLPPPPPLSYPPPYPHHLSLSTFPSHSNPLSLPLAPPASLSLSTLPPFNPTTLPPFHPYLQLPPHPSLHLPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJ97</accession>
    <name>A0A423SJ97_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative WD repeat-containing protein on Y chromosome-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017788</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003280">
        <property type="protein sequence ID" value="ROT64280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJ97"/>
    <dbReference type="STRING" id="6689.A0A423SJ97"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051242">
        <property type="entry name" value="WD-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 49-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44324">
        <property type="entry name" value="WD40 REPEAT DOMAIN 95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="2">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="388"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="586" mass="64539" checksum="487D6FAFD256D07C" modified="2019-05-08" version="1">MYPLLYEAFSPLAKPFNTEIRCSLVQRRRPALSCQQEMCNRLQEVNGRLVEVCGRVRVMTMAGVHGAGVKRVTFHPATSTLVSCSGDPRTSLVVRGSDHTAKSYTFTSSTLAPPTIHLSRSTRLSALLSSNHPPLSLHQPSTYPTLTVFHSSLLQPSTSLAPPTIHLSHSNRLSVLLSSNHPPLPLYQSSTSLTPPFFQFFSPPTIHLSRSTNHPHSIFQSLLSLNHPPLSLHPSFSSSLLQPSTSPAPPAMRVVNPLPPPLSPPGRGVRVFAVEWALHLLVTGSSDGQLRVWNPYVPEAPLSVLPAAPARAPPADILIWTPRRAIVTCDADAVVRIYGVEGGRCVQAVSLSFPGGSAGLSVRPLTLLPSGHLIVSCRDYLAALGPSPRPRSASIAPSADLGRSEPQSDAESDEGVGDEEEGDLEDEREEKRLEDDLPLLSGDESRERARIRRLVRQGAAFCCLKLPSPRPGRGRRISKRMEEKKMQRILQSLGKEEETEARKSNLFPYISHPLSIPLHPLGFPWQSVRGRDGDLIRIPNVKWWQRRDYMLKEEEAEMPGEEEDVSTGCQEAVWLNGRNSMRFLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJF7</accession>
    <name>A0A423SJF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003281">
        <property type="protein sequence ID" value="ROT64273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJF7"/>
    <dbReference type="STRING" id="6689.A0A423SJF7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="642" mass="70095" checksum="33F967C7DA4198BF" modified="2019-05-08" version="1">MMAKATRSASHRSDWGLIRIVPNPAILPIRKSFDLDNADPISFMPRLSACEDGFPRGIIGVGDPLNLQYSAPPPSPSPLPLTVNPLPPWPSPQLHPLSPSLPSTPPLHPYPLPSFYPLPSPSSPHPISSPLFYPLSPFHTPSPPFFPPPLSTPPPLHPYPLPSFYPSPFLTQPLHPYPFPSFYPPRPLSTPLHLPSFYPPPSPFHTPIPFPPFLPPLPFPHPIPSPLPLPSFFPPLPFPHPHPLHPCPFPSFPPPSPFHTPSHLSRTLMLASPPLPPLLLCLPFPTSAFSASPSPSSPSPTPASPPPPHFFPSSLPLPPLPSPFLRLPSLLPLPTSAPPLPLLPSSHSPHFPPLPPPPPPPTLRLPFPLARPPQPLDSGADGRLTKGLSSSHSTSTQRASLFHGYYPKISAGDVREVRGRRSSLCVSSAVINCISRPVAPARLMARHLFFAFYAIRHFSFLIIREEIYVFICGAALGSSEKMFPPIPSLSSSSLLTLNVLHIFPHIFKNLLPPSLLTPPTPSLQNLSSFFHTFNAPFPPYPPFPLPLPSIPPTPPFKSPFPISSPLPPKPLPLSLQTHRPTPFKTLRSLHPPPSPFLPYHPPLSLYSPPSPSSLQYPFPLPFLQYPPTPPSLPSPSQCCHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SJJ2</accession>
    <name>A0A423SJJ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific protein-tyrosine kinase</fullName>
            <ecNumber evidence="1">2.7.10.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_017706</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003260">
        <property type="protein sequence ID" value="ROT64362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SJJ2"/>
    <dbReference type="STRING" id="6689.A0A423SJJ2"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002009">
        <property type="term" value="P:morphogenesis of an epithelium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00132">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05040">
        <property type="entry name" value="PTKc_Ack_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09539">
        <property type="entry name" value="SAM_TNK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001118">
        <property type="entry name" value="Tyrosine-protein kinase PR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000780">
        <property type="entry name" value="Tyrosine-protein kinase PR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055175">
        <property type="entry name" value="ACK/TNK-like_SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050198">
        <property type="entry name" value="Non-receptor_tyrosine_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049587">
        <property type="entry name" value="TNK-like_SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24418">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22931">
        <property type="entry name" value="SAM_TNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="838"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="882"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="926"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1002"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1060"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="116"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="13">
        <location>
            <begin position="382"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="CRIB" evidence="15">
        <location>
            <begin position="482"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="454"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="520"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="719"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="454"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="582"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="732"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT64362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1248" mass="137444" checksum="2DF33CC88EBC0AE8" modified="2019-05-08" version="1">MTTVPRGPGLYEFLTEAELQHYYNNFKNDLKVQNVGQLKFVADEDLQAMGMSRPEVRRLKKYFHKYCPQTYLSKFKKILLARKDGQDSHEVVVPDEAGDRPSVRVPSKHIIPADAIVINKELGVGEFGVVQQGVWTNEEGERIQVAIKCLSKERMQTQPMEFLKEAAIMHTIDSEHIVRLYGVVLDTNALMLVTELAPLRSLLECIKEPSLRVSFPVTSLCHFSIQICDGMSYLEGKRLIHRDLAARNILVFSKNKIKISDFGLSRALGVGKDYYQTNFNVNLKLPIAWCAPECINYLRFTSASDVWAFGVTLWEMFSYGFQPWAALTGQQILEAIDEPNFQRLEQPEACPKEYYTIMLKCWQHDPAKRPKFADLMDILPDCKPEQVQVVRDCEDPPTTPGGKRERLQYSVGDVITVLDKRPVTDNPGVWKGVLNTGKTGHFNPANTVTYLGTNIPSNKSSFQRGDGKNPYSSRRRLRPEMISGPQGDFKHTGHVGLDGAYFGDVSFLGDKYHQLPKQIVTPYKPSDDHDQSTSLTRASSDVSDRAPLLKKVGDKGKSGPAAEHNWSDTASEDQPDSPARTRQSDHEYHEISDEDEPLPKVEPFRSSSFDLGPSLMDEVFKALGGSASSGPSSLDAPGSLPPLTPTQQSQALLEDNESHNVKNEIKEMTNKFSNKECSKKKQAMVKPISAADQRTLDSAIAMANALASKSILELDRNLESSADSDGVPDSPITPSSPSKQGGSRFSFKFHCKGSPKPERRHFSAEAASIPDIQFRFALSLFLSRLRGLLSACSPLPAPSVPLRPIRPPGLSPGSLYLSYSLNCLSSAFSPSLLSLCRLVLSAPAFPISAASLSSCLLFRLHHLSFFSRVPESMRCRWPARRISLFCSRICSTLSLLFFRASSLLALSFSSVFLPAVASSLSPQSPSLFSVVVSLSHASFSHLLFLSLVSLSSVSSSISLSSRSLRLSLSLSPLSSSLFPLPWTRPSLNSSSSFRPRASLSLFHVLLLSISFPPLCIYLVLIPSFLLFLHRSLPPSLSSTSLFLPPRSSSSFTPLSTVSRFLFDIPTLGPAHSFFFFFIFLLLPRPHALYSVSFPCIYLPHYHSSSPPPRLTSLPQTLYSSLVSLSCSLPLSSSLVLLLLSPLPLSYSRSSHSSSVSSPSPSLSLHLSLSLPLLSKPTILGGSKNPVSHTYPLYNQLVIIIIPSLTLSARANTFTLSPLSTPVPNPVSIFIIPSPWVTGGSGEVSLSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKT1</accession>
    <name>A0A423SKT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Centaurin-gamma-1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_017262</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the centaurin gamma-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003189">
        <property type="protein sequence ID" value="ROT64791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SKT1"/>
    <dbReference type="STRING" id="6689.A0A423SKT1"/>
    <dbReference type="OrthoDB" id="6136903at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08836">
        <property type="entry name" value="ArfGap_AGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01250">
        <property type="entry name" value="PH_AGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000001">
        <property type="entry name" value="Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051282">
        <property type="entry name" value="Arf-GAP_GTPase_ANK_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45819">
        <property type="entry name" value="CENTAURIN-GAMMA-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45819:SF5">
        <property type="entry name" value="CENTAURIN-GAMMA-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="166"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="11">
        <location>
            <begin position="390"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="549"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="582"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="623"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="624"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="650"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT64791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="661" mass="72034" checksum="C8A5CC0A396CB857" modified="2019-05-08" version="1" fragment="single">MPRERVKAQNPRRRLKSGVGLVPVSLAFPCSKIVAQRLSQQGLTPNNSRPGTPTHLLRYPSTNNGYTPAPYSNISAPLTPQITSSQQVTPPISGSSPSHMFTNTVAKDGTLRSSHGSGAELTAMTRTDSFRDDGFKRVSAPGAGQQGPAHAQLHAHHVQEEPEKIEPVHAGYLYKKSNKALNKDWKKKYVTLCDNGRLTYHPSLHDYMEDVHGKEISLQYTTVKVPGMKPRGSKVVPGSGGSDPLSAEMHTLNIASVGTPGPPLTGRSSLGGPLQSNKDKVTLTSYETLHDPAGVNGLDSASISSKIETPNVKKRHRRMKSSGNKNAECEDSDGYEFSLVSLDNKQWHFEAGSQEERDEWVTAIEQQILYSLQGNESNKSKTRQGHPIDAQTIATLKNQVPGNLQCADCDAPNPEWASINLGVLMCIECSGIHRNLGSHISKVRSLDLDEWPPGPLSVMMSLGNEVGNSVWEAHTRGQTKPNPRSSREDKERWIRAKYEAKEFIAMPQSGIPLNEQIVDCVCRGDVQRLSALLPHAGDAVNSPLAPHRDLRTPLHLAAAFPSLSCVQLLLWYNASVKICDAEGRSSLFYARTAGDKEVIDLLLQNGCPDSVVAVPPITPHTPALSHSTFPLSNTTPQPSTLPRRKGSISRKPEMLDKLQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQ55</accession>
    <name>A0A423SQ55_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002952">
        <property type="protein sequence ID" value="ROT66347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQ55"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="514" mass="54041" checksum="31C1AF5EE165B3B2" modified="2019-05-08" version="1">MDGDQGARKSREGYGQDACRGPLTLPSALPRTPLPVLPTPTSLPLPPSPSHPSPQPLSPLTLPLPTTPTTSPANLGPFPSLLRKPALPSLPPSPSPTASNPPSSALLITPSLLYPLPFLTPLHQTPTASHPSSPHHPPPASPLTLPNSAPSSEHPYPLPFLPLPPSPPLTSPSNPPPPHLLTTQPSLTLPLPHSTPPLRQPPPHPSPSTTICPSPSPSRPFLITPASPYPPPSAPTTEPSKTPLLSPSLITPVNPFLPPLLSLPHAPHHPHLTVTHHHQPYSTLPPSIRPPPLSTKPSKIPPPFPPSSIPQLAPSSLLPHSTKATTRNSPPAPTPPPHNPPPPRPALNPHLPPLPQNPLPSPPIQRPTRAPQPRLFHHYQTEPSTSPLPRPNAPSTSHPLTCPPSSPPHQPHPLLPPSSSLSPPTQPSPTHQPHNPSPSSPLLSPLTASSSLSPNPLPPSCPPSPHDYSPTPTTPLTLSFPSLLQTPYLLPHPQSSPLPPSLLSPHHHSPPPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423STQ8</accession>
    <name>A0A423STQ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Carbohydrate sulfotransferase</fullName>
            <ecNumber evidence="9">2.8.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_014354</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sulfotransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.2.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01002800">
        <property type="protein sequence ID" value="ROT67563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423STQ8"/>
    <dbReference type="OrthoDB" id="2019940at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137:SF63">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT67563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="54258" checksum="714CE2FBBD5B5255" modified="2019-05-08" version="1">MRLRVRLKSLAFLSLVSLCGVIYTFTGSHVGNWIWESDKPRRVARISADDLHTLRGYPWQAPAPATVGSSTSKLTLNDTLAHLPKGKTNPPCDRTCQFRRLREQTLVADAQIHSKGLLKNNNASKARVTPHMTGLAKVRESLKECDRACRIAKLKSTRLMRGGYSSRVRVENVTLPNSWTVTRELIDRLSARRSHVKEVCKKYELDRPSENYQPNAWEFLVNEEYGLVWCNVFKAASSTWFYNFNLLAGFSETELLHAKDTPIQLARKKYPRPTVDELHKAMNSTPQPLSFMIVRHPLQRLVSGYRDKILSGSRFYSKLARTIIKQYPELGPGETRERPKSWGVFGKNVPRSVVPSFPQFVQFLLDEAARGQKLDEHWTPMSQFCTPCLVNFDVFAKVETLEEDGNYIIFSAGIEDVIKPKRINRSRNEPTDAVADKFLCQLSQQQMKGLLQLYKYDLELFQYDASKYVNCTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXG1</accession>
    <name>A0A423SXG1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002630">
        <property type="protein sequence ID" value="ROT68823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXG1"/>
    <dbReference type="STRING" id="6689.A0A423SXG1"/>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="360" mass="37273" checksum="F838D3D5A0E8815B" modified="2019-05-08" version="1">MWLVAQGRVPLDGSARTTGAVLQPTDITTSLAHLSDAIGALAQNDTDAAKLLLHLCTQHLMVAAMGMSSGDIVGGSGEEDVDVTLCEERRGCQNASAMHQTSFPVTQALVSLLAANSSLIHLAGKGEAVTSPVTASGGQGDPGIQLANALAACILSTRLPHSHRQWAATQLVECIGGRAQLAEHCSDFPGPNISSAADFTGALPRVPTSYLEGHTACASGPSGCQERTCLLPEHTLVFQQDENDSNYSVNPPAIEHVVALPTGRHIAASSENVLNIWPLNSSTVASWTSSSIITALEAPLHGVCDLMITGHHDGSVTLAAFTASGIIPNPIRHAGSRTGPVQCLEWSSNCCLLASCGKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZJ4</accession>
    <name>A0A423SZJ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002548">
        <property type="protein sequence ID" value="ROT69582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZJ4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="40368" checksum="74A235FC2BB939D5" modified="2019-05-08" version="1">MTPPSVVRCEKNTTATPTARDNDDAGAEGSDNSTEPELPEAQIQALLNCVVAGTKVLAFLDSGRARSASFNGVRLGVSFSGAGSLGILTYHEPEAVLRCCSTSGGDREGAMRCARRDAHESPPRAGGFVRCLVNGLKGGLACVDSDTAKVLVPRLLVDLSQPEVDVWVVNDQTVPVEIEQGFVLCYAAIVEVSLDRLEYDAESMDQDSGVNPENVGLSSGGALDMASSTPIDDGSEPDSLMADLEDRFDFVHGLNDFGYNTDEFEVFPVCSFENEELPSSVGAVGVRRVDLAHLSSVQREQLVQVLDRYPDLFIEGLPPGVVPHMKHKIKTTDDQPVRVKQWRLPESRCAALLWMRSMPYRPPDIGASTGRISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T1D2</accession>
    <name>A0A423T1D2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent FMN reductase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002445">
        <property type="protein sequence ID" value="ROT70276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T1D2"/>
    <dbReference type="STRING" id="6689.A0A423T1D2"/>
    <dbReference type="OrthoDB" id="68575at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050712">
        <property type="entry name" value="NAD(P)H-dep_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543">
        <property type="entry name" value="CHROMATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30543:SF21">
        <property type="entry name" value="NAD(P)H-DEPENDENT FMN REDUCTASE LOT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADPH-dependent FMN reductase-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="195" mass="21513" checksum="45CFAE5EB96876DB" modified="2019-05-08" version="1">MSLRLLVFLGSTREGRMGENVAKCVINMLREKEHQADLVDPLMMQDGHIHQPLHFMKNQDEAPEWMKTTHASIQAANGFVIVTPEYNSTLPPALTSIMDHFPPASYRHKPCAIVTYSMGSFGGIRSAAAARPLLSELGMVSTPSVCVIPQVMGKFDSEGVCSDERIQKNLAKVVSEIQWYAEAIEEKKKVSGVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T236</accession>
    <name>A0A423T236_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleoporin Nup37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002408">
        <property type="protein sequence ID" value="ROT70599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T236"/>
    <dbReference type="STRING" id="6689.A0A423T236"/>
    <dbReference type="OrthoDB" id="340259at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037626">
        <property type="entry name" value="NUP37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22806:SF0">
        <property type="entry name" value="NUCLEOPORIN NUP37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22806">
        <property type="entry name" value="NUCLEOPORIN NUP37 P37 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="115"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="319" mass="34242" checksum="3E7987EE74B37401" modified="2019-05-08" version="1">MEVNIAPALSVNTRTQVLALEFSPYEWSRGLLAVALPTSVAVYSIKFKEEGDGTSEECGQVWEWHVSSQPVCLAWSPNATLRAAPRCLQVTLGSTDHKVTQLTSDLGDSHTAQDVLSHTDFVNSVTYNGDSGNFVASVGDDLTARVWDSSLQSQVAKFLLTSPGMVVRFHPEDPDLLLVAEKVGVLRVYSVAGGCSTLSVRCPGPLLSADWSIPDPSLLVAAGAKGLTVWNLASQQPRSEHVEVGGGEKVLNVAVCRSVTGLVATHAAPHTVRVTHLHSNKVPIAAHLKVVGGISWHQNLPYLAVGSDRRILFWKIDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3X2</accession>
    <name>A0A423T3X2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">28S ribosomal protein S25, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_010477</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002330">
        <property type="protein sequence ID" value="ROT71209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3X2"/>
    <dbReference type="STRING" id="6689.A0A423T3X2"/>
    <dbReference type="OrthoDB" id="5919182at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040049">
        <property type="entry name" value="Ribosomal_mS25/mL61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13274:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT71209.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="141" mass="16232" checksum="C34353C3C42D39EB" modified="2019-05-08" version="1">MPFMKGKAPIRRTLKYLESSRLVLKERVKLQYKNPQVQVATFKNLTPTPFVRIFLENGEDILVDVDSKSRSEIHDHLKTIICKSESTLQKEARELMINPANFGWGCDRQCICEIPGQVPCPGIIPLPNHMRGKYKFGEKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T686</accession>
    <name>A0A423T686_PENVA</name>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002217">
        <property type="protein sequence ID" value="ROT72019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
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        <property type="term" value="F:dynein light intermediate chain binding"/>
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        <property type="term" value="P:microtubule-based movement"/>
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        <property type="entry name" value="DHC"/>
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        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
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            <begin position="3268"/>
            <end position="3282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="3364"/>
            <end position="3373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="3374"/>
            <end position="3389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3505"/>
            <end position="3518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3635"/>
            <end position="3646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="3665"/>
            <end position="3683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3695"/>
            <end position="3710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3769"/>
            <end position="3780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3953"/>
            <end position="3964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="3985"/>
            <end position="3994"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="4063" mass="448202" checksum="F2830C95A61333D6" modified="2019-05-08" version="1">MEASGAEDDDIPEHPGVELPEQEHSSVDISEKTSIPKDKNEAKHIKDNLLLPEDNYNNLTDVESLDGGEELTNPLVVEAELEQVYYHAPQEEPHQSEVELAASDGCVVRKRQVVASMCQAREIRRFWSQDRNSPLQQSELNELEGAVGGNVVEEVASVGDIIQQFEGRVGRLDKKSAHKQRLQRGSQSPASRSPSHPRQVATVKPLRESQLQQQDRNGRVQEQPAEPHSIALASGFVPRVMESLSVTKSSPEAYEEDPTHASVPYPEGTHEATQIAEHQTTTVSQEQASSGLPTPGTKAGSAHGKSKLTEADLAVLESMVIAQEAEVEEMAFAHDQAEAQAKAQEEQLRKKGQQQKPKVKGQKKQDQAKGQLQQGKVEEQALLDKAQAQIHQEKIKGQLKDKKSAQPEVKNETQSKAGQVQQSQEGQKLPSNVESLIQPTQTQQVQLGGLAQSTQGQVESLIQPTQFQSQAQQVQVESLIQPTQVKGQAQQVQVESLIQPTQVKGQAQQVQVGSLIQPTQVKGQAQQVQVGSLIQPTQVKGQAEIQFENLSQPPLMKSQAQSQAETKDQMQQGQVEYILQQTSGLVQQPQTGEAIQGQVGLTQQLRVNGHQQQIQTQVQREGQSPQDKVQALIQSQGQVQTLKQQETPSKQIQPETTTKIQQSTTRVVSPGKGHAPTLASAATPAGQTKQQQFGDLTKRVADVASTMASTLESITAVAEGLEGSHLSSDEGEEQLMLMRDSPRWEDEEIQAEETDEPRAIKAEIKLLVKTTEVGKESIEIRSIREFVESDEKNLSGFGGIVPSPVPEAGRVTPQGDRVYTLQRGSPSARTPSPRFVRQQQSSPVSSYIQPTHDEFDLMAQVRGFTDLLPSCVSDGVLHGGCPEAQGMDWEGKSVDSMYTETVVQARISMLPAVDTSEGVAPTSSPTTTLPCATPQPSTSPHTDLTFQTYDLTQRPPYSHLNLEPSHLHESHLVEPQSFDISPSSVTKLSDPLFLEKGFTSATEGLSKLVTSPSAASLQSESVAPYTGTDDMAAASVTYNTSSAVLSIGPVSPTEDSSEDHAEIDRTSTELSPDSVRFEQDMLETRTEDEAPDLDDDMMAGSPVLGPELSERVFSVEATEDTDITTPMEMRDSHTERDATASNLESVDDKEGTEGKSDLKDQCWDTEDNITCLAQETAEIHSRVIKLQEKVQAQEIDRTTAKSEAELILNTVADIREAVSNGKGESDEQKSKMAQDILDSISSISDTVAKIIQNLTPSDVETSSLLMKGETGVTKTESTVIEAGSPEEGSPSDSNIRDQTFSDLLDSDDINRESLEDEFEKLAAEMSLSPKAEEALVHKPEATMTTVPSDAITYPVSSSIIYPSKTPDALQATQREPAEGIIDTFNTIGEASVDEASEDSIGDVVVRRASSRSGPRPTTFPLCLLQPEVVGSSPEAQQYFRQQQEVLEEMGRQGSLHMDVTDLRALTSPESLAGGNEFEDNEAEDSSRETRSNLRKLVKSSSSYENLYDGADLQAASSEDTPTTSQLTSSLGDPFSTKTHLPPEMCSSFENLYMKAREADEKLVHEANLLAGEILDEAVQEAVQEGVDSSTSLSPATLHASSGTHSQQVNDDSELQVCQHEDTIKSGTADQKKTPSTKPVSQEEGQRPPDESTIPSRPTRRHERTFSQASNIYTGAIPTETKQEGKKGDKETIPEEADGVSETIKPYSERKQFWESVTGQSFEAKGTQLIKAETESDTDTTGTDGTVVEQRIPDKKPSVGESSDSEAEYLAHREKPAFYENQAFIGTEKIDVPKEGDRDGAVSPFEVRRRAESQDLPSPEDIAFKDVSSKRALFEKEIKRQSMEIEESQSWKRSSKEYDETVVISEESASSTLQKKEERKQTLEETVESEKDLSKMKKETREDIVSKTDVEKVESEQKKDKVSKKDDVSEITESSKLLKEKMQVKEKKSLSEVSTADSRVVTQTDLLSEKKEKESTEKAGKVSMVDKKVVSQTDISKEKIEKEVLEKAEEIIHESRENEGAILSRTVSKSEEKAESLSEARETIQTRSTEDQDTSRDEITEEDMTRTEETSEEEADELMTKEKVTVNVTEETRQLGDTHETVVRETTTTRDGEQEQRIIKETKTQQTVMADGSTVKTTSITTFTTQLDTKETDEFPEKGKIKKEIFTKEMADEPSASIPEEKDVYKTMTAKEKSEAFVEQRMKSDIFSQELSSSAEDQSPEHKVITPKETGAPVSLQAKTAEHPLTSPIRVPEESVQEIVWEVSQERSETVLSETVEDIPSHQPIESHQVKEIPREEQKKPAKPRRKSSGATEGRLSEEEARKLAIEIVEEVKMEAVKRSPIAPPAEEFGERDGAAKPPFPRPSPESAFTEETTTKIEKYIQEQLGDDVDEKQLKLIESVTARKTEMLHRKMIGSEYQHSMEITDEDLRSSGAELSPIEHQMERLRQMTEEDDTQRYAREPSEADESESSIIIHETADDVMSSEYDQANQMITKTLDALKTAELGKVERPIDTIKEVPETTVLTAVTETRDVTVAEKTDFAKLTKQEVQETARQLVKEVTEKAQESEAVRQASLTAAELRQGSGSREHSRTPSPKPGSRKGSWMDDEDLRREFRRDYEDKKKMFKEEMTSDKDVFGEGSAKESKEMKVSQQKSSDREVHMESSMTESMEESSTVESVRSIEGKIRAEVITSVVKEVKEVETEKKEEVVMRKKGHVEEFNRRSGTDFDAYSSSGESHYFTAAEGTSDSRTGSRPCSSDVEALISERTTGTSEYDTALTSQDASQYSSYSTSSQDYRTAASSISSRDSMKSIDSESSGHLASFELSEASETLVPSAAELEKDMDLLDQDAAEEEISHSHHTVIPQLTIQSDTPKSEDAPGSFEVESDEADFEQDGKDTDSYTTSKMKRSIEMTFYPEPKPLSTDKKGSVTESVASSLEESTVSEVSMATVVEQDKSMQGSTTTDSNMTASSVSEQMMSSVEGQDFDHQVTCTDSGVLTTDTGDGDMTLHSVTITATSVPPSTDDQSTASMCTQVTSETRAQVELTESEQFFRANGPTEVDYVPEYDDEEVRGARPAVAPTVPAFQEAAGAIAGPSEGPQKVVIVEECYETEADQEYGQMMRESEYSELAEAELQYSLDEQPEAEMSSMLVIEEPIERPRTPEPGFIPSSRPTSMIIQSPEEPEEFTEVDKRFSAVFSTTYEERDEGSRSSVSEMMSIDVPDITVTEHTLPMPSQYCYPDLEREEDFPECRALAEAEDRGPDIPATPGSQESASTCASRKSSSTDSEQGREYCLDDMAHGPSFGSFEMVEADEIDDFSEYERTLYMHEERMMEMSQIKEEDEEEVEEERRLSSSPIPIPTQLKAVKIDNSNTPSESQASDETEETDETGDPTIEEQRRWLELQFEESDAANYEYQQTGFIEHVYSGPLEDIEEEREDAERRDLSHITKNSSLSSTPEYDVLAGRKFFTRSGEHDDVSMTSLQEFENLEQQVAVEAIARRASSGSQESLNGKRPESKSGHGDDISVGSFASLQEFERLEKECLIVEQIERKAQEEAAMLSEIEEGHESQMSESESCETLSEPGRASVEGEEYDQRLFEIDEIIRQAQDNVEKFDKSKAEYEGVRLQDIVSVDGSGSGSSHADRTPSVGREEGDADSLEEAQLPELDLDQTGVTSVGSSAKQDTMSMSADSIEAAPRHKVPRETSQDSLEKAEARSSDPMTTSVDSIEFVSRQDLMTTSTDSIEGRRRRPDAMSASTDSIEPSRRDIMATSIDSLGRDDSSGRDADISSGSEQVRPLPRDGGVMECSLESLEPTSSQATHATYQYDTDSIMSGSFTSGCSNTLVASTDDFPDMMTSSMYLPEGELPPESEEQYIRYMQASGGTATEIVQPSSEEGYSHTVTRVVRLPPEAKQITFTGPDAQKKMEEYMQSFNAGEHTTQEEAVDAQGNVHIRRVTQKRIVTDPKETKEHGFSVADPSVEEVETRDEHASRSPPPGPPPGSRGPREPVLPSLEPNTVSGTASQASLCCTARRVCPRTLHSSSLSSLSACCVRMTSRQPSALSAHFVIVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8J3</accession>
    <name>A0A423T8J3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CTCHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_008820</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002113">
        <property type="protein sequence ID" value="ROT72775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8J3"/>
    <dbReference type="STRING" id="6689.A0A423T8J3"/>
    <dbReference type="OrthoDB" id="431817at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008988">
        <property type="term" value="F:rRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041370">
        <property type="entry name" value="Mlase_EEF1AKMT1/ZCCHC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039846">
        <property type="entry name" value="ZCCHC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017921">
        <property type="entry name" value="Znf_CTCHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13493:SF3">
        <property type="entry name" value="RRNA N6-ADENOSINE-METHYLTRANSFERASE ZCCHC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13493">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10237">
        <property type="entry name" value="N6-adenineMlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51270">
        <property type="entry name" value="ZF_CTCHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTCHY-type" evidence="10">
        <location>
            <begin position="348"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT72775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="55508" checksum="09C4A71395B84F00" modified="2019-05-08" version="1">MAKLDHRWVYGLHIQNSGILKKCPTVLFERFQSNGRSRQYYACSACRDRKDCSFFHWADEKFSKTKRDLWDKFIKDSEPKDTEEELSRSLNEVLSVLPSERIYCANCSTLLTTARRSKHKACTLITPLTDIQLTQPSSFLPPRESAKKEAQYLFASSSVDVIINMLVKLQAKRVLCVGAPRIYEAIAMSEKLEMSALMLDIDERFQSFFKPQSFLRYNMFNHYFFDGKKAKETYQNFIAEKEKLVLVSDPPFGGRMELLAHNMKRIEQDWRTARHLDPQEQLPVLFIFPYFMEPQVLHNLSDFVMLDYQIDYDNHPLYSSGPKSMKNGSAVRVYVNQPASLFSFPESEGYHYCKPCNRWVFNNNKHCKKCKGCMSKDGRTYRHCDQCMKCVKPSWLHCTECSRCQPQDHKCKSQGVNGFQRQYAIFVEVLTTSAQIVQRKRNVENPLAVRMQERRKKGGNRHCHQIFQKKERET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T909</accession>
    <name>A0A423T909_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti-lipopolysaccharide factor isoform 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008617</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002086">
        <property type="protein sequence ID" value="ROT72950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T909"/>
    <dbReference type="SMR" id="A0A423T909"/>
    <dbReference type="OrthoDB" id="6361026at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024509">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038539">
        <property type="entry name" value="Anti-LPS_factor/Scygonadin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11630">
        <property type="entry name" value="Anti-LPS-SCYG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0044">Antibiotic</keyword>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019501466" evidence="3">
        <location>
            <begin position="25"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13508" checksum="93C7F0786E51FD5B" modified="2019-05-08" version="1">MRVSVLSMALVVALAASLAPQCQASGWEALVPAIANKLTGLWESGELELLGHYCNFSVTPKFKRWQLYFRGRMWCPGWTAIRGQAETRSRSGVVGRTTQDFVRKAFSAGLITESEAQVWLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9D5</accession>
    <name>A0A423T9D5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002075">
        <property type="protein sequence ID" value="ROT73056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9D5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="46676" checksum="57A08229F7F7AE2F" modified="2019-05-08" version="1">MYPWTPPHPHPPADVPMDPLPLGIPPDLSYLSHPRLFSPLPLSLTPLTHPTSSPPSSPSPPLSQPHSSTPLSHSHITHTSSHPAPSHPPHLPQPPPTYPHSLTHPLTQPHSSPPPHPVPLSPSPLLSQPQLSPHPHPPLTPPPPSPPTPPPPTPFPLTPFSLTHPTPHPPHPPPLTNPPTHPPPLLSPPPHRTSRCTRLWPLWCSSQWTGRQVPSTRLSPYVFINPCRCCNTTRTQAQGNIKRYSSNSQLTLSPHIYISCVCLGVGTPTVAWPEVSRVVTSPVNSNRWTLLTGQITVDGACAAEDGGHSLARAPLGGVRSAVIRCTDKDFLVVVVHSGWHLFAGRMLEGAAHERARVSAGEAIRQCSEGVRRGAPLLQWLNPFRGGLACPGRALGLIMGRGRRGHRMSSFLELLFNTVWFLVRFPAEIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9N9</accession>
    <name>A0A423T9N9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_008419</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="12"/>
    <dbReference type="EMBL" id="QCYY01002058">
        <property type="protein sequence ID" value="ROT73157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9N9"/>
    <dbReference type="STRING" id="6689.A0A423T9N9"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000001">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5 12" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT73157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="47030" checksum="3843A259645D3AF3" modified="2019-05-08" version="1" fragment="single">MPSSTSFDPEMLPDLLPIYYKRLFPYNKYYQWLSYGNVPKTYFPHREFCFTLADDIYVRYQSFKDQAEMEKEIKKHCPHKIDIGAIYSFRPKEHRTVSVFTPLEKELVFDIDMTDYDEVRTCCSGADICHKCWKFMTVAVKILDAALREDFGYQHLLWVYSGRRGVHCWVSDASARALSQPQRSAVAEYLQLIRGGDSQSKKVNITQKVHPSIKRAEGIAKKYFEELILEDQDLLGTPDQWGKVLTLIPEQSLRESLEKVMSQCSNSHQRWNTIQSEISKAINKSDFKKGIKPNLVTEIILQLVYPRLDIHVTKGLNHLLKSPFCIHPKTGRVCVCFDPRKADAFDPMAVPNLSQLVEEINQFDAGKTDEERAVAEYKKTSMKEAVIVFESFLAGLSKENASRRQESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA13</accession>
    <name>A0A423TA13_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GW182 middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002040">
        <property type="protein sequence ID" value="ROT73305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA13"/>
    <dbReference type="STRING" id="6689.A0A423TA13"/>
    <dbReference type="OrthoDB" id="5919166at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035195">
        <property type="term" value="P:miRNA-mediated post-transcriptional gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052068">
        <property type="entry name" value="GW182_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026805">
        <property type="entry name" value="GW182_M_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13020:SF25">
        <property type="entry name" value="PROTEIN GAWKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13020">
        <property type="entry name" value="TRINUCLEOTIDE REPEAT-CONTAINING GENE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12938">
        <property type="entry name" value="M_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GW182 middle" evidence="3">
        <location>
            <begin position="49"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="576"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="604"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT73305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="672" mass="71086" checksum="CC8EA05811BC2806" modified="2019-05-08" version="1">MGLDDTLMELSNRGIAGMGGSSAGDAWRNPPLEEHAPFDLTNPNFQQRFPPAPHHLPFTNQQGSSGNSPHVRALMQHIQMAVQAGYLNPQILNQPLAPTTLMLLNNMLSHINMLQKFTQQQAIWQAQAHINKNSSQTLLSLNVSITKTKQQIQNLQNQIAAQQALYVKQQQQHQHHHQQLNSHMTGGPPGTQNDFFNKPSLPDQLCSSFDFLAVNNNPAIINVQQQGSRLHQWKLPSLENDEPDFIRAPGAPGKPSMPQSQSSPNLTPLLGPSNSTWSLNRTSESGWPESSSGGSVDVANNPGVEKVVPNMDSRWVASSQANASGSYGLDIKPFEPGKPWMMKNIEDDPNITPGSVTQSPLALGIKESVDLLSSISKTSTTNTASDMAGPLTSFSLTSNTWSFNPGPGHHAANSPLSGDSKLSSGTNGKSGSAWNESSQGGSNNLASELWGAPGNKLRGPPPGMSVGSSNNKIGVGVSGGSWGALGRSTSWSGEQQRNPPNSALHSAAVVAASGAWTNSQLPSQLPSTWLILRNLTPQIDGSTLKTLCMQHGPLVNFYLSLNHGFALVNYGSREEAAKPTHQGQAAPPTPGPTNASSWGGSGRGSTPTSQSSGGSKVDSWGNGNSSNLWSSGPGGSSSLWSGANIGEGDPHRATPSSLKPYLPDGLLTSESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDU1</accession>
    <name>A0A423TDU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001875">
        <property type="protein sequence ID" value="ROT74606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDU1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="272" mass="27650" checksum="C1893EAE854A3879" modified="2019-05-08" version="1">MLHRLLHSSSLLRVRYPKDTVVEAQEAPEEDSLEEAEDFLEEDSPEELVVDSLEEDSQEVVDFPVEEAEEQADLAVVLEAEVLEAALAVVLEADLAVVLGGDLAVVLEADLAVVLEADLAVVLEADLAVVPAADLAADLAVVRIWRWFWRRISVVLEADLAVAEEQADLAVVLEADLAVVPEVDLAVVLEAALAVVLEADLAVVPAGFGGGSGGGLGVVLEADLGGSGGGFVGGSGGGFGGGSGGGFDGGSGGNGLSVGYSPPAPSNAYSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH82</accession>
    <name>A0A423TH82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001731">
        <property type="protein sequence ID" value="ROT75812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH82"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="41078" checksum="AA3D9FCC762AB3F2" modified="2019-05-08" version="1">MPSISVTISLSLYLCSPPSIAFFSLPFSLSVRPTSLSLPIYLIVSLLSSAVSPSYFQLSLSPCRFSLLLSTVLFPLPFSPSYFQPSLLLCRFSLLLSTVSLPLPFSPSYFQLSLSSAVSPSTFPLSPPSSLAPVAAIMEKKSRMKSVQMDESSVTRSRPVWVKGLGFASRVKPVSPPSVSRAGLPFVPVILEPLFPVRADTSPSPCLLPLSLPCPCPLCLPCSSLFSVSSLFFPVLPCSPLSSLFSPPPCSPPCLPCLPFLLSPPCSPCLPVLSPCSPPLSPSLLPVLPSPPCSPLSTSLPCPPLSSVFSLSSPLISLFSPLFPVLPSLPCSPLSSLFSPLLPVLPCPPCLPCPCLVTNTKPKKAKKRADDKGEREGPARATQSGEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI42</accession>
    <name>A0A423TI42_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001692">
        <property type="protein sequence ID" value="ROT76122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI42"/>
    <dbReference type="OrthoDB" id="6367822at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="46901" checksum="BFC6C10769F63388" modified="2019-05-08" version="1">MEDDDDVKADLPQFPFEAKTGARETPLAHHDCLPRVNSGDVSVVEERPGLCCALYNLCCFRETPRISPKRKNDGPPPSIPIVHRFSFPTSVSQQRAHSSPAPAARPPAPRDEQPREPPRNTNPNRPQLPRKLPGRPRDSDDDQDARPNFASGPRRPQLPRKLPFRPDDSEGPQPPRKLPNRPSDADRPQPNRPNSSDRPQFLSKPQSEPQTPRKPVPTRAEGLAGPQPARKIKVRPRPQQRNDVEPERAEPEELPAPVQTAEQEDRRGPSGVEEISADPEGETAPLPIPPAVERTPKIISGQVAEPAESVTPPPAISPEDIPTYLPIEIPQDSSAPPTPSGRGDVFEAPQLSPEVQTAPEPSEAPAGSPEPSLPSPQEPEEAQSPDLTDVPAPPAAATRGRGTRTRGRARGSRGRARSDTGAEEAASKRSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI93</accession>
    <name>A0A423TI93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001686">
        <property type="protein sequence ID" value="ROT76170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI93"/>
    <dbReference type="STRING" id="6689.A0A423TI93"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="44650" checksum="F75D8F6B7C3A4D5C" modified="2019-05-08" version="1">MTLLLIETILRPAEAEWRKAPRSSGIWKCLSFYAARHGKLKKARKRVEISPNYFRSPVYDRRERRRERYRQNQKRRSKQYDVTAEVPITPCEPLGSGKWALAGNGLPWLRSWASGSLALFPTFSSCFPLCSGSPPRSSPSCPLSDLRFPPQHPSSPRPLLLPSPICQPPPPPPSCPPQYVSLPHPPTPPALPNMSASPHPLLPSPMCQPSLPPPPPASPICQPPPPPSCPSLPPNMSASQPSPTPIPPPPPTHLHLPPPPLALPNMSASPTPPASPMPLPNMSASTHPPPPALPNMSASPHPHPSCPPQYVSSPPHHPSSLPKYPSLPPCPPPFPLLAEPRRRPASAPSAAGGSVVGVGRRHSLINNNYLGNKKNPVMPLALQSQEDHRRRCLWASRRRGTLGRPRRCPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJX4</accession>
    <name>A0A423TJX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_004634</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001611">
        <property type="protein sequence ID" value="ROT76761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJX4"/>
    <dbReference type="STRING" id="6689.A0A423TJX4"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFDF" evidence="4">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="5">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT76761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="208" mass="23224" checksum="ACB6DBDF27A62CEB" modified="2019-05-08" version="1">MGRGRGMRRPGGQRGRGQIFNQGNRQRQIQDQQLFEKDYDFEQANEEFEELKNQLAKTKITENGEKKDDSGHETAGGEDVEDPTCYDKAKSFFDRISCESIERSKGKSQRPDWRLERKINVETFGVSSARRGFYPRGRGYYRGGYYRNYNYNQGYYRGGGGGGSYRGGRGGTRGNASSVNGMSQRGTGSSNGGGSAYVPAVRNSTPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKA4</accession>
    <name>A0A423TKA4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001605">
        <property type="protein sequence ID" value="ROT76837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKA4"/>
    <dbReference type="STRING" id="6689.A0A423TKA4"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057033">
        <property type="entry name" value="Ubiquitin_IARS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23567">
        <property type="entry name" value="Ubiquitin_IARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Isoleucine--tRNA ligase cytoplasmic ubiquitin-like" evidence="7">
        <location>
            <begin position="369"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="49281" checksum="2624FA785EEEA828" modified="2019-05-08" version="1">MVRVMAPFTPFITETMYQNLRRVLKPGTLGQGDTSSVHYLMVPQPMKKLICPEIETCVGILQNVVELGRYIRDKVNNPMKYPLPEVVVIHKDQQILDDVLRLEKYIKEELNVKTVTTSTDKQKYGVALRADMNFKLLGARLKGDVKKVQQKVAELTDVEIQEMLQAGSINILGHTIDASELNVKYSFSGEKAEELSSKYEAHADANVLILLDITPSQDMLDEGMAREVINRMQKLRKKANLVPTDEVTVWYEVKDGDLARIITSFTEYIETATKTPCKPLSEKNSTDVIIEEVADVKKTDLKLVITRGFCAGWAMTASTVESEVPAAQGGLTCPWIDLEKTSVKNLVGKTIVVTSAPNKVPVGTSAVKPYSRFVNVEGNGKKASVLLENPCGDGIMTVPIFVKFVMNVLGLKSKPRLFTDPEKKKELQLNGTSLTKLQGSTVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLL8</accession>
    <name>A0A423TLL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone deacetylase complex subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004015</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP130 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001537">
        <property type="protein sequence ID" value="ROT77344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLL8"/>
    <dbReference type="STRING" id="6689.A0A423TLL8"/>
    <dbReference type="OrthoDB" id="8197871at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024137">
        <property type="entry name" value="His_deAcase_cplx_SAP130"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031963">
        <property type="entry name" value="SAP130_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13497">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13497:SF3">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16014">
        <property type="entry name" value="SAP130_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase complex subunit SAP130 C-terminal" evidence="8">
        <location>
            <begin position="747"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="468"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="648"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="554"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="677"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="713"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT77344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="811" mass="82945" checksum="C1E0A5154FA25FA5" modified="2019-05-08" version="1">MRTSAQPIGQPGSNVPGPRGSVVGQRLVPASTNGGWIRNTPSPAHTGKVTGLSMHPGVTAPNSGCPEAVDAHASSRARWWGHNNVPHRSAARHCLQWFYQRAGRLCEDGHTEGAKGTGPKAVHITQPIGPQKYGGMGGVMSGSGRSVVASGGGAGGGSSSGTIYSPGNPMVTTMSGPGVNPQTTIRTQAPPAIAVRITTAPVSTATSSSQVTSQAGTSIGAISMTSPSGSSPGAILTHQSPLHRTQQDQVPLKTPIVRTPVASHQSKGGVQAQTLAFSDGPKVITQPAQGPPLALAQISGLAGVTTQKAQVNTHTVSQQHTPNVQHRPGGSVMGSSVGRVMGGTGIPVAKVLPQQATTPNQGAASVAGPPRGSHGQVRAQSPGQAADPQAPHTNVFLQRPHAGVTVTSGTPTGQAERVVTTVPQYSIAPPYYYEQGQNTYQVGGPTLVPHTLSSTHYVPTNVQSGSLRVTGGGPNASAGAAPGHGGGPGQIVEGPGGQAPAPLPAMKPGASPRPSILRKRPDSDGTPLKAAKNLTAALCLPMPSPPSPKRPDSRGNGNASSGSTTISANSSPGLQIEELDGNSGGAATGNSAELRTPPSIKQEPPEDATVVLPRQPVLCSMSETSAGLTTGIVTTTLNVPQPHLSVTSMHGASQALADGLSPRKKPRKQQLTGNELQEARSSEDDLDHPPVKKTKREIAEDNHDLEGSEDEGGGWSEPGGGSSGGSYGGSGGGLGGANASNAVNATVVITNRPTMSLLSSFRQTWKPRHNHFVRHTDVKPKDERRLTVNEIANQKMALQRVNGWKGKWMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN71</accession>
    <name>A0A423TN71_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_003391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001458">
        <property type="protein sequence ID" value="ROT77911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN71"/>
    <dbReference type="OrthoDB" id="10039931at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001384">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379:SF121">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24379">
        <property type="entry name" value="KRAB AND ZINC FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="247"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT77911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="484" mass="54850" checksum="2801D7EA5C7AA954" modified="2019-05-08" version="1">MDVEDPIKIENNFDENDSLASSEVFQAIDSEDKKTSVRVRRSVRNKRNLDACLQAQRNPKKKLKGEKDVKKDKILKQADKDEEWTEESKPKLGNISSCEICKEVFDDAKQLLKHRGDVHPSIYCYVCQQCDDVRYREKAKLTQHVRLIHKVPVHKCPGCNHEAPSQNALDKHIINEHPESRYFDSDDVRLVCEVCGKSKATQQDLRRHQIAQHSKEKPFSCQQCSRTYTSKESLKSHLRTHDDEKPYKCECGKSFHKSSVLRRHQRSVHLAQRPPHVSAHENIQEELDSVHIGDEDIEGEERMVVITLKECNPPAVYTVRSASSNLEEIMVTNESSLQSPENTFISGTLPHTQTIDTIPVLHHQLGSIGTGRIGITTPVLFTTLNANPPSGTHGQEALQENLPQTFATEMTSVPSSLQANAIPFQEENGSTDSIKDERIVQFQDETPVTCTQLTTQILQLPPLQTNPSNNAQLTYVTTWPFPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN78</accession>
    <name>A0A423TN78_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001462">
        <property type="protein sequence ID" value="ROT77885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TN78"/>
    <dbReference type="OrthoDB" id="10072641at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="49693" checksum="B24AB3AF3885F5B2" modified="2019-05-08" version="1">MSSFDSENYNANQEQRDGFERSQHTGNIRSNNNSYSSSPLSSCPPMQKNRSGTQEQMSRQEAMRSADVPVAEQMKIAADQDQKERTSIVELQERITRDLMDPHTQNLLKELLKQSKKTVEEKESPRKDASPDPATVASELEELGMDLEEVGEEVDDIFGKSISRSVEDSIGNSFQEGLERGKRLRQVQASTNPSPPSRERGHEPRPSSRGPDTRYPSDWNVKSTVEDPRKHLHSSLQSSEEPNAKDIPDDAKSSGSSFWVPAFDWHKAQKVKKDMSYQSGANDWEVETPYVQRKEKMGERQAGHHPTLKDTKQMVPPSAISSSSSSSSRVPPVPAMTSQLDEEATASRITEMNKDKAPQSRPMLFPSGHSYSPSVPPPSSQTRAHSSRSVEVMRQLMTMNLQYKCGPRVNGKRPESQNKGGAMIQVLTQVQRIRRPARCMKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQ53</accession>
    <name>A0A423TQ53_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transcription factor MafA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_002729</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001366">
        <property type="protein sequence ID" value="ROT78553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQ53"/>
    <dbReference type="STRING" id="6689.A0A423TQ53"/>
    <dbReference type="OrthoDB" id="5974330at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004826">
        <property type="entry name" value="bZIP_Maf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008917">
        <property type="entry name" value="TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024874">
        <property type="entry name" value="Transcription_factor_Maf_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10129:SF44">
        <property type="entry name" value="TRAFFIC JAM, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10129">
        <property type="entry name" value="TRANSCRIPTION FACTOR MAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03131">
        <property type="entry name" value="bZIP_Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47454">
        <property type="entry name" value="A DNA-binding domain in eukaryotic transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Basic leucine zipper" evidence="6">
        <location>
            <begin position="412"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="287"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="503"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="453"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="518"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT78553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="537" mass="60047" checksum="0AF5B12CB8FAC219" modified="2019-05-08" version="1">MVRLLREGGVTQRAESEGDWLSGVVAWVRPRAFPPLGAGLSSARLRLPIRWANRGLYFGCSAHLGYPLPHLKSLAPPLKVSVTSRRSCAGPARVARAVWHGSHHHYFSIDSDHSVTSTRRGTEPRTKKLFESQCAPLALTPRHLGVTSTRRPALGLITGFLSMTQVCASVNVRTRSLTISESVSARLLFVRLATQHVLTRRDSCTGQSSAIGPDRSRGALTPRPPNTARGSDSCDELLNKMADENLASEYVADFMLEPLEDAICVKENKDLHGMGGMGMSRVHTHMMTPHMPNVKPHSQVPGTPPDTPPGSSPPNGSLPPSPHFQGMPQHTLMDEMWAYNRYMQEPLDLRPGPQCGGEQLEAQTWMLDRKWESQQKYPLNTLAPNGKGAGDQQASCQMGLQGIQHHNASVYISDEELVTLSVRELNRRLHNMPKDLQTKFKQKRRTLKNRGYAQSCRTKRQNYKMELENVNRTLQTENQRIQNDANQQIGIYKCRSRPKTRAEARSCTPCDRVAPRTTRTRSRVRRASGTRWRSPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TR67</accession>
    <name>A0A423TR67_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lactosylceramide 4-alpha-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_002345</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001313">
        <property type="protein sequence ID" value="ROT78949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TR67"/>
    <dbReference type="STRING" id="6689.A0A423TR67"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006688">
        <property type="term" value="P:glycosphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051981">
        <property type="entry name" value="Glycosyltransf_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042:SF21">
        <property type="entry name" value="ALPHA1,4-GALACTOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12042">
        <property type="entry name" value="LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="8">
        <location>
            <begin position="221"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT78949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="40827" checksum="C1E9AF6D415EA3FF" modified="2019-05-08" version="1">MFFMSINRERRVMVNVILLMCAWSLSVTLIVPLMVGNGGAVRNGADGDAASWIQHLCPNYRTKPGSRDTLSWRPPSAQDIFFTQTSCAAALSIREACAVESAARHHPHQQVLVLMTAPDLDRSHPLLQLLQTLSNVQLAWLDLDRVFVEGGLREWHRGRQWMFSEGRTSAEVSDAVRAELLRRYGGTYIDLDAITLRPLPTTMNWLGRIDSKLVTAAVSRFAPGHPLLQSVVDNIPSSFDPHGCCSIGPNLFTHLLHQSCPKNVTTPSSAHPDEAEHCNGVTIFPKSYFYPIHYGYRKDQLESIFREGEGLGRAFLSSTQAFSLHLFNSLSHQGQVSPDGDSVLSEVARRNCPALFHLVKTKDRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSH8</accession>
    <name>A0A423TSH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001252">
        <property type="protein sequence ID" value="ROT79388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSH8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="487"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="525"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="571" mass="62023" checksum="A7E3FD797D1A2D4E" modified="2019-05-08" version="1">MESSLADAHMQYYTLRIGPSPPSLPSSFFRLSLIPSPPRSVPTIPLPSSFLLPPPRLLTPPIPSPPPPPSFWISSPSTPLLLPPPPLPSLPPPSLESKTASLLPLICTAPPSFLRSATSLSPPPPSPSVPGSAHPSPLPPPYLCLLNPIPSPSLAPSSLSVLPPSPPLPDTSFSPPTVLPPHRLPPIPRPPRSNPPSFLLCPIPLSFHLIPGSLPCLPLSPPPFIVFPISPPPVPPPSWILPLLPSPVPPPFSLLVSSLPSPHLSPLSSLLPSSSLPPLLPAPLYLRHLLRLPLPTSFLGSSPLPLSTPSPPFLPPPQPLLPSLSPPVLPGSSPSPPLLPAFLLLSHSPPLPLLLPPPSPPPPSIFFLTSPKPGLLLIVSCNLSILHHTCNNTRAADTHPHAISLSPRLSASSRPYLFLFLFLFLSFSYFLFSFFIFLYFLALFFFSLSFSLLLVLSLSFLPRLLFHFFRLSSSSSSTSSSSSLSHLLLFYFFYFLLFFFFFIFLPPPPPPPLPSRHSSFPSISSRLLFFLLLHHYLLLLLFPPSHLFLLVCFFFLLHHLLFPLASFSSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSJ7</accession>
    <name>A0A423TSJ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Angiopoietin-related protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_001869</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Lectin involved in innate immunity. Agglutinates all types of human erythrocytes, Gram-positive and Gram-negative bacteria. Has a stronger agglutinating activity towards Gram-negative bacteria than towards Gram-positive bacteria. Specifically recognizes acetyl group-containing substances on agglutinated cells. The hemagglutinating activity was inhibited by EDTA, acetyl group-containing mono- and disaccharides, N-acetyl derivatives of amino acids, other acetyl group-containing substances, propionamide and benzamide. Enhances the antimicrobial activity of big defensin against Gram-positive bacteria but not against Gram-negative bacteria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001250">
        <property type="protein sequence ID" value="ROT79408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSJ7"/>
    <dbReference type="OrthoDB" id="6145874at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00087">
        <property type="entry name" value="FReD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.215.10:FF:000001">
        <property type="entry name" value="Tenascin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.215.10">
        <property type="entry name" value="Gamma Fibrinogen, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037579">
        <property type="entry name" value="FIB_ANG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014716">
        <property type="entry name" value="Fibrinogen_a/b/g_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002181">
        <property type="entry name" value="Fibrinogen_a/b/g_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020837">
        <property type="entry name" value="Fibrinogen_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47221">
        <property type="entry name" value="FIBRINOGEN ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47221:SF6">
        <property type="entry name" value="FIBRINOGEN ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00147">
        <property type="entry name" value="Fibrinogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00186">
        <property type="entry name" value="FBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00514">
        <property type="entry name" value="FIBRINOGEN_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51406">
        <property type="entry name" value="FIBRINOGEN_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibrinogen C-terminal" evidence="9">
        <location>
            <begin position="195"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="426"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00053344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT79408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="54010" checksum="4C281A5676138773" modified="2019-05-08" version="1">MDTIILLLQRLSDRQAAFETLQGQRAERIDNINYRLTRMELLAEERKGVLSEISNAIQHRMETTDSEMDRITGLMDNVKDSITALIQRHVDLRGLIADLPRTADPEENNGQKLQAVAASVFSVHSVAQAIQQELGDLGLNLTQLMNTTGTLGYIRSNMVSKQYLLQSLNELKSSQTVPTVSVMPRMMGTRGRTGGKVEKEPEDCWQLLRQGKKKSGVYRIQPQYSSVPFFVYCDMETEGGGWTVIQRREDGTVDFLREWNEYKHGFGNLAGEFWLGNEKIYLLTSQHVSKLRIDLSDFDQQSGFAVYSAFAVGSELEGYSLKMLGEYRGDAGDSLRYHVGRRFSTIDVDNDAWPERNCARDHMGAWWYRACDTSNLNGRYLHGPVPSDHEYSGLYWYDFRGPRYSLWRSRMMVRRGGSVGRPVFKDIDEIKSSTTTARPEEPTPAEDDEIHSDPEPYDPYATYNGYDPYAIYDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TT44</accession>
    <name>A0A423TT44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001217">
        <property type="protein sequence ID" value="ROT79624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1224"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1249"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1355"/>
            <end position="1373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1388" mass="151553" checksum="26BA8132214A361E" modified="2019-05-08" version="1">MRPFFPLPPSIILYSSLLPPISLSFYLPSSFPPSPFLLPTLSPPHLHLSSSSSSSFSTLPYLFRISHFPSSHPLSSSSHLILVLILLNSPIPLPYLPLPLIPPPFLFTLPSLSPFALLSPHRPSILPLFVHSPLFVSPPPCFSLTALLSPLFVHSPLFVSPSFPSLSPFLFTLPLCLPSPASLRLLSPPFCSPSPLCLPPPFSPHRPSIPLFVHPPLFVSLRPASLTALLSPSPPSLSPFTLLPHHPSIPLFCSPSPLCLPPPCFPLTALLSPFCSLSLFVSLHPAFPSPPFYPPFLFTLPLCLPPPCFPLTALLSPFFCSLSPLCLPRPAFPSPPFYPPFCSPPLFVSLALLFPSPPFYPPFVHSPLFVSLRPAFPLTALLSPFLFTLPLFVSLRPAFPSPPFYPPLFVHPSLFVSLRPAFPLTALLSPLLFTLPLFVSLRPAFPSPPFYPPLFVHPSLFVSLRPAFPSPPSIPPFLFTLPLFVSLRPAFPHRPSIPPFCSPLPSLSPLRPAFPSPPFYPPFLFTLPSLSPLPAFPSPPFYPPLFVHLPSLSPFACFPLTALLSPLFVHPSLFCLPSPCFPLTALLSPLFVHPPLFVSIRPAFPSPPFYPPFLFTLPFFSLRPAFPHRPSIPPFLFTLPLCLPSPCFPSPPFYPPLFVHPPLFVLLRPAFPSPPFYPPFCSPSPLCLPPPCFPLTALLSPFLFTLPSLSPSALRPLHPAFPSPPFYPPLFVHPSLFVSLALLSPHRPSIPPFCSPSPLCLPPPCFSPHRPSPSLFVSLRPLSLTALLSPLFVHPPLFVSLRPAFPSPPFYPPFLFTLPSLSPSALLSPHRPSIPPFLFTLPSSSPSALLFPRALLSPLLFTLPSLSPFALLSPHPFYPPLFCSPSPLCLPPLLSPPALLSPPFCSPSPLVSSALLSPHRPSIPPFCSPSPLCLPPPCFPLTALLSPFLFTLPLCLPSALLSPHRPSIPPFCSLSPLCLPPPCFPLPPSIPFLFTLLFVSLRPAFPSPPFYPPFLFTSPLCLPPPCFPSPPFYPPFCSPSPLCLPALLSPHRPSIPPFCSPPLSPLSFPSPLFPSPPFLSPLFVHLPSLSPSALLSPHRPSIPPFCSLSPLCLPPPCFPLTALLSPLLFTLPSLSPFPCFCPHRPSLSPPFFCHPPLVCLLRPAFPSPPSIPPYFCSPSCPLFSLRLSFPSTALSSPPLFTLPSLSPLRPAFPHSPRPFSDPPLFLFISLYPYNAFASLSLLFTLVSPFFSTSLAFLCVLFSLSFTLVSPFSSTSSYSLCPHLSSSPSPPFLPPEFATIYSISPISRSPSPPFRPLLPSLLQLLPRHHVRPFSPSPPLPHLPFPLLRPTSRYSRVLCVSKALLLSISYSLFLIHCHRDAKDKIPWPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTU2</accession>
    <name>A0A423TTU2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001182">
        <property type="protein sequence ID" value="ROT79865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTU2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003882">
        <property type="entry name" value="Pistil_extensin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01218">
        <property type="entry name" value="PSTLEXTENSIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="594" mass="63044" checksum="3DE179CD9BE62D81" modified="2019-05-08" version="1">MLSISGGLGHRVGLGHRGGLGIEAPPTPVRPQTHTPQAPRPALPPLPPRRAVQYPLETAKHQGRIIRAIQRVSGLIPGSSHLWLPRERSGPLTPSLPLAPSPPPSPIPPPSLPPSLPPYPSPLPSPIPPHPSLPPSPSPPPFPIPLPSPTSPHPSLPIPPHPLPSPIPPSLSFPSIPSPFPIPPSPPPSHTPLPPITPLPSPRYPLSLPPHPFPPPHPSLPPPSPFPYTPPRYLPPSLPPYPLTPSLSSIPLTPSLPPTPSPFPHTLSFPRYPLPPHLPSPRYLSFPDTLSLSPRYPSPSPHKPLSLPPIPLSLPPDTTLFPSPPSPSPPSLPPYPPPHTPLPSPLTPSFPPSPLPPPTPPLHPPIPSPPLLLQYPPPPIPSTYSPIPPSLPTITPLTHPFPLPSLPHTPPSPNPLTSLPSPIPPHYLPFPPYPLPLLPPSPPHPPFPHTLNPPFPPYPSPLPSPIPLTSLPPPFPPIPPHPLTPPFPPYPLTPPFPIPPHPPSPPLTPPSPHTPSPLPSPIPPHPSFPHPLTLPSPYPSPLPSPIPLTLPSPPLPPTPPSPYPLLPSIPPSLPPHTPSLPRPERRHTSSFSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TV80</accession>
    <name>A0A423TV80_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PiggyBac transposable element-derived protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001128">
        <property type="protein sequence ID" value="ROT80350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TV80"/>
    <dbReference type="STRING" id="6689.A0A423TV80"/>
    <dbReference type="OrthoDB" id="6368840at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029526">
        <property type="entry name" value="PGBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46599:SF3">
        <property type="entry name" value="PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13843">
        <property type="entry name" value="DDE_Tnp_1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PiggyBac transposable element-derived protein" evidence="2">
        <location>
            <begin position="158"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="436" mass="49822" checksum="1525E7357D7C219E" modified="2019-05-08" version="1">MSRQLSVRRSRRPRSSPAIRSLSFEEEETVDDPRPLLYTFRHSSDEECGDSEEVYATPAEHRRTKDHSEGSDSEDESELSDCESEEDFVPLDDTSLDSDENLAEYVRRRRARTAPVSPPLFGGRGRTSHVASTLPQLLGSTFLTWMLNPHLKRYVAQNPRTPSAHMKGWEDTTVKEVRTYLGLRFLMGLQSKRQMRDFWSRDPLMSSAIFPQTMSRDRFDQLTEALHFADNQAERQADDRLWKLRPVVDVPNKVASIDESLWAFKGRHQALQFVPNKRARRGIKVYKLCSSLGPEAGYTTYLHGDVPASMKAVIDLLERGGLMDKGYEVHTDNWYSSPSLFHHLQKRKTSAVRSNRKQMPTDLQAKGRGSVDFRSTDSGMLALHWLDRRPVTMLSTVHTSEMVALPPNHQGIQRIKPKVVTDYNNGMKGVDFSDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYA4</accession>
    <name>A0A423TYA4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Prenylcysteine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_025378</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000969">
        <property type="protein sequence ID" value="ROT81456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYA4"/>
    <dbReference type="STRING" id="6689.A0A423TYA4"/>
    <dbReference type="OrthoDB" id="437369at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001735">
        <property type="term" value="F:prenylcysteine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030327">
        <property type="term" value="P:prenylated protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030328">
        <property type="term" value="P:prenylcysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Prenylcysteine lyase" evidence="9">
        <location>
            <begin position="233"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="536"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="673" mass="74729" checksum="657E8E52BB82EF73" modified="2019-05-08" version="1">MATVKKVKLDVRPFQSSWTNDFGFIQQNGRAVCALCREDVVCRTSSVKRHFETKHGKTFKDSADKAEAIQKAVSRYEKQSNAFENQGTSKNKATGGQSNAFENQMTSKTRQQAQSTAFENQRTSKNNATEASYKLALCIAKHAVIGGGIGGTAAAYFLKHHFGDDLVLHLYESHAVGGRLAVRSIAGNTYEIGGAVIHPENKYMKEFTSKYGLSEKEKCLSRMGIFDGDEYVFQASNFGFADTVKLFWRYGWDVHSFHKSTKDLLKKFNRIYDLQGQGQAFSNVSALLKAVDQDLLDMTHLSVRDWFKKNGYKDNIIDELVTAVTKCNYGQNADIHALVGAIAVAGGDPNLWSVKGGNMRVAEELLKHSHATLLKRKVKEIMLNEDGNFMVTSVEAETSDKQGERRSRNSSVDNKEDKSRSKVYDLVVVATPLTKDTSGIQIPLPPPTPILYYLPPTLPPPANTPPQSFLHFSPYLPPTPTIYPSPLPLLLTLHPNPFPPPPLSTLLLHPSRPHSTPTPPLFPHTPYYLPHSPPLTRHTNPTPSPSHTSSPHLPPTPTIYPPSPLPTLPLPPPTTHPLLSTPLPLPHFFPPIYPTPYYLLPSPFPHFFPPSTTHPYYYFLPLPTLSPPHLPPTPLSTPPHTFLPPTTTPYYLPPSPLHLPPPTRPPPSFPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYW2</accession>
    <name>A0A423TYW2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein MIS12 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_025185</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mis12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000940">
        <property type="protein sequence ID" value="ROT81659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYW2"/>
    <dbReference type="STRING" id="6689.A0A423TYW2"/>
    <dbReference type="OrthoDB" id="1884855at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="6" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT81659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="216" mass="24435" checksum="BBDFB35399960835" modified="2019-05-08" version="1">MASVIPDEQYETQFFGFSPSSFLDGVKGLVLDRLSEATEQLEGHLSQIPEEIISKEEVSRGIGLLRQQTDSNYTKTMQKLEAHILENVMKIPAHVLLPSDVEQQSQASASDITLLHTEMEKLRTQLKNEKLMQAKLKDELQDIEQVLEEQQKMKTEVFNESWMTQLEEAKEKLLFVHENDEETLAVAAAIQKKAADLRISGNTPTAVQILTTNILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZB0</accession>
    <name>A0A423TZB0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arginine/serine-rich coiled-coil 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_025046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000916">
        <property type="protein sequence ID" value="ROT81784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZB0"/>
    <dbReference type="STRING" id="6689.A0A423TZB0"/>
    <dbReference type="OrthoDB" id="9946564at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="237" mass="25370" checksum="06C981E73853D360" modified="2019-05-08" version="1">MHTILRDHRVVAAQVPEVGINTTGNPGDTEGIHQAVQEAAHAAGHALADLTPGAETRTVTGAVAATLAHGHGHVRDTAGSTRSQSTSAGEEVQARGQNAVADTQSLVQLEAAQTEIAALSQIKEEPYRSKQIEMTESEKLAYSKAVEEIEGDSFVQHSFKSSSGDKKSQSSANDQSDETFNFGTQAEVTAKGGGKFIPLSDDSLFSPHLFGDPEEREEKYFRRIFSLRQKAVLGEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZW4</accession>
    <name>A0A423TZW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Neurotransmitter-gated ion-channel transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000900">
        <property type="protein sequence ID" value="ROT81978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZW4"/>
    <dbReference type="OrthoDB" id="6350162at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="2">
        <location>
            <begin position="206"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="48829" checksum="7C15387544387ECE" modified="2019-05-08" version="1">MPLRLLLSCQQSARLHTFLQRERELHPLITQPTNLHIPVTFTYCKTSTLHPSLFYYPQHGITASCGVLPNGEAQPHSISSPNNLLACALRPDSQLTYRGENQHHPNTYIINHHSTYTKPTPTPYQLHNQTNGTYNISIPTTSPRLQPHTRTKLFSPETQYLATGLIHTHTLLLSGGKGSKLLRLARSHRLTPYYWAWFLCKILTIFIPTTVINIISYATFFFKWYDFQNRIMVSLTSLLVLMTLFSQVADTLPRTSYFKLVDIWFFFSIIYTFLVIMQHTVVEYFHLYEHEIRALKKSETQKKKEPDLPKGLDERSELHRFWSEAIKKTFETLQTTVRIASTTENKKETKETKEEEKKEKCPNWASKFVNKFGNIFTAVLYVVVNLVFWIVAFMQKIQETYKDYLAAISKPEIPDNVGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U447</accession>
    <name>A0A423U447_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative calpain-A-like isoform X5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000684">
        <property type="protein sequence ID" value="ROT83459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U447"/>
    <dbReference type="SMR" id="A0A423U447"/>
    <dbReference type="STRING" id="6689.A0A423U447"/>
    <dbReference type="OrthoDB" id="424753at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00214">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000114">
        <property type="entry name" value="Calpain a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033883">
        <property type="entry name" value="C2_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022684">
        <property type="entry name" value="Calpain_cysteine_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022682">
        <property type="entry name" value="Calpain_domain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183">
        <property type="entry name" value="CALPAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10183:SF433">
        <property type="entry name" value="CALPAIN-A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01067">
        <property type="entry name" value="Calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00704">
        <property type="entry name" value="CALPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="4">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="343"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR622684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="474" mass="54197" checksum="7FB7AB7E4B6070A2" modified="2019-05-08" version="1">MENGLVKGHAYSVTGARRFRVNAPRRPYVELLRLRNPWGDETEWKGLWSDGCEEWNLIPSSERDKLQLSIAADGEFWMSFSDFAENFDELYITSLNPHTVNEEAKEQLFSLADVVTEAILHSEVIRAAEVKAVKMWEVVTFDGAWVRNATAGGGDRKHRVFCSNPQYILELTEADDGAEGTCATIVTLMQKNRRVNQLPIHPIGFYIYKLEEGERTPNPLTVSWLRLNVPYFYTKTFSRARTVTHRLALDPGRYLVIPCTPEPDQEAEFLLRVFCEKLVRMEEYDEEAQILDIAYESEDEVDHSIEDHLRAVFREAAGEANDVDAVKLQAMLEQLFPSAGFADSLDFTRSFLAMMDLDFSGTVNFYEFEALFSSLSRWVRVYNSRKDEESGLLSGHSWGLGDALRDLGLQIPRRIRALVVVRYGDQQGHVALRDFLMAACRISVMLVRFEAHRAEEGQHANIPLTDWLTNTLYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4A2</accession>
    <name>A0A423U4A2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000673">
        <property type="protein sequence ID" value="ROT83534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4A2"/>
    <dbReference type="OrthoDB" id="425619at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="560" mass="60713" checksum="CDDEC81801D92B51" modified="2019-05-08" version="1">MGICQYDSNSPQPEPTPIRQQQSRRQQGHRAANCPFPERRHDQPQSTSDTLEGKSVARTPADSVSHQSGRPIVPINASGSPVLAFVDTGPPSAYLIINKCHLPVHFTDTQSLHVSLVSVPDVFTTELDASAAKCTATAGSLNTTIANKNVVSITSQGEPTVRCLADDMSFQHETDILKTSTTQTCHTQEDQARTLPFDSRHVHVHRATSIPGKAAKFVRCKVSRDVTGDAVVLEAQSGPMFMVPNSVAKVTPQRECDVWVVNLSTRPLTLKNGKKLGNVYGVSEREVGTSDGGEAGSPLLVEESPGLPGISQVEESLVEPEEIEHPSFSEDEFDCAYGLYDFGYEDDHFTIFPDVDLSPSPACAVTTHSQTETVGSLVMRRIPPSVRDGPLGSRWAGPCRIVRKLGPVAFLLEDTAPPNTRRRAHINDLKPYVPPLELDFGPDDPEPEDEPVATTSVSKGKTTPWEESLLDAVRVHQPGRPRSKVTTQLGDVAEHSNDALPGRLGRACRPREEQFPSDDTIPGSNRMDDAGLDRAQGRYHPRRICPLSTAAFALLAGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U4L9</accession>
    <name>A0A423U4L9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">adenylate cyclase</fullName>
            <ecNumber evidence="4">4.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023211</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000661">
        <property type="protein sequence ID" value="ROT83612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U4L9"/>
    <dbReference type="STRING" id="6689.A0A423U4L9"/>
    <dbReference type="OrthoDB" id="10035433at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000008">
        <property type="entry name" value="Adenylate cyclase type 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45627:SF8">
        <property type="entry name" value="ADENYLATE CYCLASE TYPE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="13 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="15">
        <location>
            <begin position="46"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT83612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="236" mass="26655" checksum="9F82BFECD3F1AD05" modified="2019-05-08" version="1">MAIKDKVRVQTMKDQAEWLLHNIIPRHVADSIKSTAKYSENHKDVAVMFASIVNFNELYDEDYLGGKEYLRVLNELVADMDELLSQDEFKNIEKIKTIGSTYMAAAGLDAKVRAENTDAHQHIFELVEFALAMQKVIDDFNQDLIEFNLILRIGLNFGDVTAGVIGTTKLYYDIWGDAVNIASRMDSTGVPGRIQVSGACAAILNRRYELERRGPVFVKGKDNMDVYLLKGRKDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U745</accession>
    <name>A0A423U745_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000529">
        <property type="protein sequence ID" value="ROT84550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U745"/>
    <dbReference type="OrthoDB" id="6366525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019547032" evidence="1">
        <location>
            <begin position="20"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="150" mass="16736" checksum="5C82BF273F882297" modified="2019-05-08" version="1">MKITASFVVVALVGCLAAAEESPQNESEHEAKFFVKRYSTRTWTFLSSFTSTVLYTCYSTGNPFDACEGRKFRRIRKMDISLSDEPDEGLAGSLTDDEFGEEKTDAEKAFFRVWVTSSTTITVTTYSTNRSVTVSVFAYCSYNGVVLNIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA18</accession>
    <name>A0A423UA18_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative homeobox protein B-H1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_012296</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000256">
        <property type="protein sequence ID" value="ROT85536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA18"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050848">
        <property type="entry name" value="Homeobox_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333">
        <property type="entry name" value="HOMEO BOX HB9 LIKE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24333:SF5">
        <property type="entry name" value="VENT HOMEOBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="44"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="46"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT85536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="12370" checksum="2F92786B76A815A2" modified="2019-05-08" version="1">MLDLLQRPALRVTSSSRPVVPPGSPSSSPDDADDEGGSGPPPLKKQRKARTAFTDNQLQTLEKSFERQKYLSVQDRMELAAKLNLTDTQVKTWYQNRRSVWHSGPICCLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVN4</accession>
    <name>A0A3R7LVN4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017723</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003264">
        <property type="protein sequence ID" value="ROT64332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LVN4"/>
    <dbReference type="STRING" id="6689.A0A3R7LVN4"/>
    <dbReference type="OrthoDB" id="8609993at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048666">
        <property type="term" value="P:neuron development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000102">
        <property type="entry name" value="Receptor-type tyrosine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF553">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 10D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="121"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="303"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="43582" checksum="D83B85367A58D1FB" modified="2019-04-10" version="1">MFSEPDTDVVAKMVPLDFSFQILHPNCSILTAASDPFPCAAAKVAAVPGGLHPFIATLISFIVISLAVSGSYFIYSVYKGSVKFEWNGTMQTASEATGKRILLVKLGEVVRRLMSDGEELLAVEFESLREQSPQEPVRVASLTPNKYKNRYSNILPFDKTRVLLERFPNDTYSDYVNASYVHSFTKKNRFIATQGPKKSTQQDFWRMIWEQNVYVIIMVTSCTEGMRVSVENKCSKYWPDVQEPPFCFPREDLIVCTTKESTKRSYVVRSIQIKKGDDQRNCLHYQYVDWPDMGCPDSPNDLVSFMMAVKPVIVLGDFHVVVHCSAGVGRTGTFIGLYNTMLEMDKGNSVDIYECVLRMRSCRMNMVQTQVGFGVVGDSGGGVRWVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYU9</accession>
    <name>A0A3R7LYU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_013637</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002704">
        <property type="protein sequence ID" value="ROT68226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYU9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="532"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="658"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT68226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="687" mass="74705" checksum="9272BF1DFEFA92E5" modified="2019-04-10" version="1">MLGGAERRAQRQRRRSPRPTSLSSLALCQHCTPPRPPLALGSRHDTRACSSARRLVPDGAGHRRRRLIASAVPPLPCCGVPSLSRSCCGFPSLSRSLSFRRCPAVGFPLSLVLALEFPSRLSFSLRRCPVVGFLLSLVLSRSLSFRRCPAVGFLLSLVLSRSLRFPSLSFCGFLLSLRSSALGFPSLSVLFVRLCCGFPSLSRSLSFLLWGFLLSLVLSRSCLVSFSLSFSLVLALGFLLSSLLALGFPLFSLVSLVPPLCCGFPSSLSLSSSPSLSRSCFGVSFSLSFSLVPLPAVGFLLSRLSRLSLVLALGFPSLSRSLVLLLLSLFSLVLLWVSFSLSLSLLWVSFSLSFLLWFLLSLVLSRSCCGFPSLSRSLSSCCGFPSLSRSLSLLWGFLLSLVLSSSWGFLLSLVLSRSAAALLWVSFSLSFSLVLAVGFLLSLLVLSFLSRLSPYGFFSLSFSFSLVLSRSAAVVPPLGFPSLSLLWFLSLPFSLSRFLHLLARSLSFSLVLLWVPSLFVLSLGLALGFPSLSRSLSVLLWGFLLSLVLSRSRFLLFSFSLVLLWGFFLSLFSLGLAFFFSLSFSLSCFGFPSLSLVLSRSCCGFPSLSRSLSFRGFPVVGFLLSLVLSRSCCGFPSLSRSSRSCFGVSSLSRSLSVLLWGFLLSLVLSRSCFVADAFSRSFFRGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZZ7</accession>
    <name>A0A3R7LZZ7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_012666</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZZ7"/>
    <dbReference type="OrthoDB" id="6373057at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="5" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 15 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="18">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="258"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT69194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="273" mass="30323" checksum="0E8F8F70D0F01DFB" modified="2019-04-10" version="1">MTPPLLVNAYWGTWVFGAFFCEIYAFLGSLFGCASIWTMVFITADRYNVIVKGVSAEPLTSGGSMMRIAGTWAASLAWCLPPFFGWNRYVPEGNMLACGTDYLTESELSKSYLYVYSVWVYLFPLAYIIYSYTFIVQAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFMAWTPYFIINWGGMFNKPMVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACATEGRDGGSDTGSTATAQSTEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M072</accession>
    <name>A0A3R7M072_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TATA-binding protein-associated factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_013832</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002723">
        <property type="protein sequence ID" value="ROT68053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7M072"/>
    <dbReference type="OrthoDB" id="10252227at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044972">
        <property type="entry name" value="Mot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022707">
        <property type="entry name" value="Mot1_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36498:SF1">
        <property type="entry name" value="TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12054">
        <property type="entry name" value="DUF3535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="1462"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="580"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1176"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="580"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="611"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT68053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1798" mass="202454" checksum="A15379257A1BC2C2" modified="2019-04-10" version="1">MSSRLDRLFLLLETGGSGVTRQAAAQQLGEVVRLHPHDLNYLLSRVHVYLSSKSWETRIAAGLAVEAIVRNIPQWNPQPVKREYVDEEMCKPVAGRLSLGSFNISHVLQKGSYLMAADEKQFEAEDENIPMDPVERINCQRKLVNQRLGLDVAEVIGVDTQNLFTNEDLTDSHQGGITSHNGQEKDAVVDIIRREMKSAGLPLSSREMNRARRKAKLLARQKSMDVSECTSDEGPEKKRMRLASSVTVDQAGSDDEERMVVDEGPVGMYPGEEGTEWPLDSFCELLATDLFSASWEVRHGAATGLRQIIKVHGRGGGKATYHTKEQMEQYHQAWLEDMAVRLVCVLALDRFGDFVSDQVVAPVRETCAQALGGILHLLSEGGVFGVLSLLETMLSWKEWEARHGGLLGLKYLLAVRDDLRSQLLTHAYPHIYKGLVDEMDDVVAVAASCLVPVSDSVVLLLDREVVTKLVATLWDSLLDIDDLTSSTNSILLLLSKLLSHLSSDASMQSDLKELAPRLWPFLYHSSSSVRGSALATLATLTSASHSAKVKVENQEVGAQVDIKQENSSNSCENVTAKVEEMAMEERSEAEESSKIDIKQESTNSHESVTAKVEEKSLEAEENIKKDDKMLVEKSPEAEENIKKDDKMLEEKSPKAEENIKKDDKMLVEKSPKAEENIKKDDKMLVDEEKQDDKKVPPSDDQKMKKDENSNQDQSTEKGEQKEEEMEKEKNEVKNEPENNQAEVKFPQEETKCEDFLEWLNPIIQPALTHMYQRALLETSEENIEFVFKIWEQMLARTSLESLLPAVCPMIASWLCLMMANPKVPLEPTLLLIAHHNKSGEGKRLRVGALNDPAEKAEAKYYLGGCEQYNDPCEKQSVVVRARCAAARLLGCLSNYVIKPMPGIVYPPEETPVLCYIRLLIAHLSSRSAVQRLAAGAVVREWASIYANQECHSLLQNALHSCLMEVVYYDEIALSFTRLQQETRDFMAMLRHYKLPLDEAFINAPVLTLEQIQNLSGHVALTLFNGGRLRPKVHSTLEERRKAIQNNVSQTSTDQISLSTTTQAIISGAVVRFRILPPKLNPIIKPLMDSIKKEKIEQLQALAARDLTKLLELCMDRQTNPNGKVIKNLASFLCVDQEFTPKIPHEESKNTGDANKQKGILSLSSQLKNAERQLLRRTSSITGRGPGRPPANAKKEDPSEVTEAILDSENQQLAEIQRRGCTTALTHVAQYFGAELPTKVPQLWDLLCSPFSVPPQNEVTVKDSQEAVHQLQLLEVVVPTLHPKLVAEFETKLELFEHWLYHPYSEVRHMTTRVMGSLATVLTVPVMTYVVEQVVPALTAIDNDNKRQGAVECIFAAIDRLGFDVVPYIVLLIVPLLGRMSDQDNSVRLMATHCFATLIRLLPLEGGVPDPPNLSDVLLQQKRRERDFLERLLDPSKIENYNVPLPINAELRSYQQSGVNWLYFLNQYRLHGILCDDMGLGKTLQSICILAGDHFSKRKEYQKLGQKGNKPLQSLVVCPPTLTGHWVYEVEKFVKRKYLNPLHYFGPPAERYKLRRFFPDHNLIVASYDIVRNEIDFFSQIKWNYVILDEGFLGTERQFMARYAKPILQSRDAKSSSKEQEAGVLAMEALHRQVLPFLLRRVKEDVLKDLPPKITQDYYCDLSPLQQQLYEDFARTQANQDINDALRSTDQEKEVGNKPHSHIFQALQYLRKVCNHPKLVLKPQHPEYERVTAQLKECSSSLSDVTHSAKLPALKQLLLDCGIGAGGGTETEVVVSPHRALIFCQLKGMLDIIEDDLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1Q2</accession>
    <name>A0A3R7M1Q2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Protein O-linked mannose N-acetylglucosaminyltransferase 1 (Beta 1,2-)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_011226</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002418">
        <property type="protein sequence ID" value="ROT70497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1Q2"/>
    <dbReference type="STRING" id="6689.A0A3R7M1Q2"/>
    <dbReference type="OrthoDB" id="10366026at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047223">
        <property type="term" value="F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004139">
        <property type="entry name" value="Glyco_trans_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052463">
        <property type="entry name" value="O-linked_mannose_GnT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396:SF2">
        <property type="entry name" value="ILEI_PANDER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03071">
        <property type="entry name" value="GNT-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1111"/>
            <end position="1139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT70497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1139" mass="128103" checksum="3040CE1D698FA4FA" modified="2019-04-10" version="1">MGTNTVPYLKEPVIRMPLQREAPIVLHDVAALKLPSWQQHITQEIKDATVLTGNPCRESFLPSPPTARSYVFYYRLDWTPSGQSDISQYHNAAMCVGLWSLSDQGHHRGVSAVRFSPNSTLYLLANFDARMDYVRRQDHTMKGGRFHPVKEDLSLLVLDQRTGRAMMRRSFRTSVEFSWWADLVWWLQRVSPGRLVVITVTGRAPHWAFVMRARSSPNWVLPSRPIWRNRRRGHGPSSKITLAFRDVNDSIYAEGTISLSAEPLPTIKTVTDKERWHYCHLHAAMGGLCDEHTPDPLPPPPPPTLPRQSALAHVPVVVTAGARHQYLYHTLNALLTAPGAQRNNVLVVLGDAPQPTTQLLRLINVNFTKVPVHGEGNLKLFRYYRSVFQLVARTFPDAPAVIFLDEDVEVSPDFFSYMSQTLWLLREDPTLYCINTYSFLLTTDNGRSASLVRRGETQVMWGYAVTTNFINESLHMWPESGENEDILTYKLLLPPRTLIHTPLGRGGTHSNCPQPKECCCRLSQGVPLGHYWAHYADLQWHLDRVAPGRILVLTVAVSGAMGLRQAALQLARLGSLFALHLTPMAHWTWVFVKGGRTISETVILQGLAQHQAHLILPLSDLPTPTTPSNQTLQQQRWHYCHLHAAMGGLCDEHTPDPLPPPPPPTLPRQSALAHVPVVVTAGARHQYLYHTLNALLTAPGAQRNNVLVVLGDAPQPTTQLLRLINVNFTKVPVHGEGNLKLFRYYRSVFQLVARTFPDAPAVIFLDEDVEVSPDFFSYMSQTLWLLREDPTLYCINGFSATGFEGRAFDKSQVIRGSVQVEWGYAVSLDFVREALASWIDEVNTLFYDFWLYTNIRKDRECVFPEVSRTRHFGMGTNTVPYLKEPVIRMPLQREAPIVLHDVAALKLPSWQQHITQEIKDATVLTGNPCRESFLPSPPTARSYVFYYRLDWTPSGQSDISQYHNAAMCVGLWSLSDQGHHRGVSAVRFSPNSTLYLLVWSSFNAWGLEVDGCNNTQQQACYNLLLPPEDAHPHAPREGEGLTLTVLNQRNAAVVFHKVFPLGHYWAHYADLQWHLDRVAPGRILVLTVAVSGAMGLRQAALNSLASAPSSPCTSRPWHTGHGSSSRAAAPFQRRSSFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1U9</accession>
    <name>A0A3R7M1U9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Elongation factor 1-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_017090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003162">
        <property type="protein sequence ID" value="ROT64954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1U9"/>
    <dbReference type="STRING" id="6689.A0A3R7M1U9"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830">
        <property type="entry name" value="ELONGATION FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830:SF1">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP-eEF1A C-terminal" evidence="6">
        <location>
            <begin position="47"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT64954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="168" mass="18255" checksum="2B3EDDEF7C3A897C" modified="2019-04-10" version="1">MHHEALTEAVPGDNVGFNVKNVSVKDLKRGFVASDSKNDPAKEAADFTAQVIVLNHPGQIQAGYSPVLDCHTAHIACKFAELLTKIDRRTGKELEAGPKHVKSGDSCIVKMVPSKPMCVETFQQYAPLGRFAVRDMKQTVAVGVIKEVNKKDQSGKTTKAAEKALKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M761</accession>
    <name>A0A3R7M761_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006694</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001845">
        <property type="protein sequence ID" value="ROT74799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M761"/>
    <dbReference type="STRING" id="6689.A0A3R7M761"/>
    <dbReference type="OrthoDB" id="360585at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="8">
        <location>
            <begin position="85"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="456" mass="51014" checksum="262479FEC87FD4C0" modified="2019-04-10" version="1">MFQIVVPTERIPPGVGYHTSVSALGTLQASQHKGQSVELITEDIELIGGPQIENYPFKARKRHSQDYIRQYLHLRARTNTFSSILRVRSQAKMAMQEYFNKEHFINIDTPILTANDCEGGGEVFMVQPLFAEVGSHESLSTKYFGHPAYLTVSGQLHLEAMASGLSKVYNFNPAFRAENSQTRRHLAEFWMVEAEEAFLSGPEGLQNLMNRIEDLLKASIQCVLDKSEEDVFTHWKQNECTEELVKAALSLPFIRMTYDEAMTLLQDNSQHFQTKPSLGDDLGKEHELFLTKHAGNRPVFVTDWPKKTKAFYMRARDDNPDVVLGVDLLLPDIGEVAGGGLREDRPQVLRKELNARGLIENLQWYLDLRTFGGGAPSGGFGAYMDGQGGHRDGVSTLPRSLMPGTCPSRKRGVDSQIPQKIISGNKASGKVLLREEKKKLLSISECSLQQQATTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8R0</accession>
    <name>A0A3R7M8R0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006369</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001811">
        <property type="protein sequence ID" value="ROT75083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8R0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="815"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="907"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="933"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1164" mass="129300" checksum="9455D8209F8D42C9" modified="2019-04-10" version="1">MEDERDKVVTAVEEEEVESRPEVVAEAEEEEEVEPLPEVVAVADEEEDESLPEVVATAEEEEVESLRRWSLRPRRSRTSPSRSWSPRPRKRRRSSPARRWSPGGGGRVPPGGGHRGRGGGGGRVPPGGGRRGRGGGGRVPLGGGRQEEEVESLPEVIAAAEEEEEVESLPEVVALAEEEEDDESLPEVVATAEEEEVESSRRWSPRPRRRTTSPSRRWSPRPRRRRTSSSRRWSPRPRRRRSSPARRWSPRPRRRSRHGRGGGGRVPRRWSPRPRRRRRPSPSGGGRRGEEEEEDESHSEVVAAAEEEEDESLPEVIAEAEEEEEVESLPEVVAVAEEEEEDESLPEVVATAEEEEVESLPEWSPRSRRRRRSSPARRLSPGGEVESLPEVVAAAEEEEAESRSDWSPGGGDRVPSGGDRPAEEEEDDKSLRRWSRRRGGRVRRRCRRRRRSSPSRWSPRSEEEVVESLPEVVAAAEEEEAESRSDWSPGGGDRVPSGGGRRGRGGGGRQVTPEVVASAEEEEVESLPEVVAAAEEEEVESPEVVVAAEEGGRVVTAVEEEVVESLPEGGAAAEEEEAESRSEVVARRRRSSPFRRWSPRSRRRRPSPARMWSPGGGGRVPSGGVTAVEEEEVESLPEAVAAAEEEEEVESLPKVVAAPRRRRTSRSRRWSPQPRRRSSPSRRWSPRSRRRGCRVPPGGDRRGRGGGGQVPLRGGSQEEVESLRSDHRGRGGGGESPGGGRRGRGGGPVHPGAGRRGRGGGGGRVPLGGGRHGRGGGVGRVPPGGCRRDRGGGGGRVPPEVVAALEERSSPSRRWSPRPRRRKSSPSRRWSPRSRRRRRSSLSGGGHRGRGEEVESLPEVAAAEEEEVQSIPELVAAAEEEEEVESRSVVATAEEEEAESRSEVVARRRRSSPSRRWSPRPRRRRTTSPSRRWSPRPRRRRTSSSRRWSPRPRRRRSSPPGGGRPAEEEEVESLPEVVAAAEEEEDESPRRWSPRRGGGDRVPLGGGRQEEGGRVLPGGGHHGRGGGRGRVPPGGGRRGEEEEEDESLPEWSPRPRRRRSSPARRWSPRPRRRRSSPSRRWSPRPRRRRTSPSRRWSPRPRRRRSNPARRWSPGGGGRVPAGKVVALPEEEVESRPEVIAAAEEEIESLPEVIATAEEEPHFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDE7</accession>
    <name>A0A3R7MDE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001218">
        <property type="protein sequence ID" value="ROT79618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="264" mass="29338" checksum="1ED6491AF8A304FC" modified="2019-04-10" version="1" fragment="single">MTRPGDHAAEVQSCRETLSTRTTLSSSISGQQNAVRRARRRSIKLCPYLNEVLIKKQVRISTSCLISCSPNTRNISLPVGLASRRSCCGRSSTKSNKPPNWSYGPPSSHLKNHAHRDFNFDPKDHSSAEVRAQNAHRKAREVYHTRVHAVHAHSDESPPISNPRVAGLCRELGILELKFRPGFDRPPRPLKVQIQQQRDGNTPIIDEKPSSRCLASPGAAVPYATRRSTASRDTSSWPVLQAADLLRLLRGLPLGLWKTRVPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFB8</accession>
    <name>A0A3R7MFB8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vitelline membrane outer layer protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001042">
        <property type="protein sequence ID" value="ROT80981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFB8"/>
    <dbReference type="SMR" id="A0A3R7MFB8"/>
    <dbReference type="STRING" id="6689.A0A3R7MFB8"/>
    <dbReference type="OrthoDB" id="6329319at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841:SF0">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="203" mass="21908" checksum="138DCE7988126D0B" modified="2019-04-10" version="1">MIKAFSCSRSLFIPPVTAVVSPVQTSSPGHWGSWHPWFYCSPGSFMHAIRIKYDDYDSYPDSGGVTNLEVFCKYPDGTAANSAVLGVNDYTPPGSWLSYQGCPPGTWIKAWEQSVTPPLGGSIDDDALNNFIFHCSSDLNGRSGLGTALSGTGDTRYPLSLGECPFSTVACGVTLMVESFQYLGDNTAVNDMHLACCFIDLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK00</accession>
    <name>A0A3R7MK00_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Reverse transcriptase RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_002541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001341">
        <property type="protein sequence ID" value="ROT78740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK00"/>
    <dbReference type="STRING" id="6689.A0A3R7MK00"/>
    <dbReference type="OrthoDB" id="6379141at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase RNase H-like" evidence="8">
        <location>
            <begin position="269"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT78740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="43369" checksum="497068F400A3E844" modified="2019-04-10" version="1">MFPRSSTYKDILQEFPALSKPINWATKPRHEVRHHIVTHGPPAHSKPSARARDRCCSAKWSLTHDAVRIIRLPAANGHLVKKKDDTRCPHLHSSHKLSGCTVFSRIDLVKAYHQVRSLRRTSPDGRHYTVCLACSSFSGCPSVSTTPLRPSKRFINDVTPRLEGSLHLHRRHPRQHLRRPSSPRLLFGRLQEAGVVINPGKCLSGAASLFSRPQPSPSRHHPNTGEGLAETVDAPYKRSLRSLQGSLASATLLNHPLPEAPLKHSRRRSRHCIGAVLQQRQGKHGEPLAFFSQTLLPRRSRYIAFRKELLAVYSVVRHFQPYMESQEFHILTDHKPLTFALHSRTRRQSLREERHLDYISQFTTDIRHIRARTTRPKMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK95</accession>
    <name>A0A3R7MK95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_021549</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMEK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000454">
        <property type="protein sequence ID" value="ROT85008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK95"/>
    <dbReference type="STRING" id="6689.A0A3R7MK95"/>
    <dbReference type="OrthoDB" id="27483at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072542">
        <property type="term" value="F:protein phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000051">
        <property type="entry name" value="Serine/threonine-protein phosphatase 4 regulatory subunit 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055236">
        <property type="entry name" value="EVH1_PP4R3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006887">
        <property type="entry name" value="P4R3-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051137">
        <property type="entry name" value="PP4R3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318">
        <property type="entry name" value="ATP SYNTHASE GAMMA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23318:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22972">
        <property type="entry name" value="EVH1_PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04802">
        <property type="entry name" value="PP4R3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP4R3 EVH1-like" evidence="5">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine-protein phosphatase 4 regulatory subunit 3-like central" evidence="4">
        <location>
            <begin position="146"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT85008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="260" mass="30048" checksum="380700B6719C8214" modified="2019-04-10" version="1">MADRMARRRVKLYALNADRQWDDRGTGHVTSSYVERLKGMSLLVRAESDGSLLLESRIQPDTAYQKQQGTLIVWSEGENFDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDIVEESEDERFDDVSDTNPWVELPPCEIGKLEDINEVISNCLHSPVRREKLAIALENEGYIKKLVSVFHTCEDLENMEGLHLLYEIFKNIFLLNKNTLFEIMFADDTIFDVVGCLEYDPSSPYPKRHRQYLKSIAKFKEVRKDFLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLE0</accession>
    <name>A0A3R7MLE0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_001386</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001177">
        <property type="protein sequence ID" value="ROT79908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLE0"/>
    <dbReference type="STRING" id="6689.A0A3R7MLE0"/>
    <dbReference type="OrthoDB" id="6378485at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058698">
        <property type="entry name" value="CUB_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236:SF5">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33236">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26080">
        <property type="entry name" value="CUB_animal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018733129" description="CUB domain-containing protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="5">
        <location>
            <begin position="533"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT79908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="681" mass="73062" checksum="145CF9169EFC0653" modified="2019-04-10" version="1">MRVYGASNRLTTQVLVAVVLLACVVVAAPGGQIPDDPDARGDDSSGPGHDLSAWEADDLGESQRMRDDKCRKQTQIHMYRITLSVPFFSNARPLFPLRPCYPSPRLPASSLSSPPVILLLRLPASSPSPLHLLSFSSVSPLLPSPLHLLSFSSVSPASSPLLSTCYPSPPSPPLFPLSLPPVILLLRLPASSPSSPPIILLRLPLLPPLLSTCYPSPPSPPLLPLSSPPVILLLRLHRFFPLSSPPVILLLRLPLLPLSSPPVILLLRLPASSPSPLHLLSFSSVSPASSPLLSTCYPSPPSPPLLPPLLSTCYPPSPPLLPPLLSTCYPSPPSPPLLPPLLSTYHPSPFPPPVFIALVQIQPDQCTTRDGFSTLGTCMPAKECTSNGGTSSGSCAKGLGVCCLVTKRCSSTSKFNNTYFVNPSNDSTLGACTLTINRMNANICQLRLDFVYFELSQPDATGQCSTDFFTVQGTSTMICGSNTGQHMYVDVDPNGGAIKMSVDRSTTTNLARAWNIKVAQIECNSRFKAPKGCLQYFTETSGSVSSFNYDTALVNGTRQLRNMDYGVCILPPDGYCGIIWEKDTTSVYSFSVSGALDALDPNLVGTTYAVERNCTTDYVIIPGGTEDTGTQNDRFCGLGFPNSVMSYAKPYILYVKTNGDEAADTLNRGFKLNYRLTTICT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLK5</accession>
    <name>A0A3R7MLK5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative high mobility group protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_021698</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000046">
        <property type="protein sequence ID" value="ROT86020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLK5"/>
    <dbReference type="STRING" id="6689.A0A3R7MLK5"/>
    <dbReference type="OrthoDB" id="10027956at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21995">
        <property type="entry name" value="HMG-box_TOX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000005">
        <property type="entry name" value="TOX high mobility group box family member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051365">
        <property type="entry name" value="TOX_HMG-box_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45781">
        <property type="entry name" value="AGAP000281-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45781:SF1">
        <property type="entry name" value="HMG BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="334"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="334"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="457"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="432"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="487"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="520"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT86020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="611" mass="64370" checksum="6288FAB9D8A29383" modified="2019-04-10" version="1">MLDRYTEPSKNTRDSDVISSPSCSVLMHQSLLRHHLSSAFTPPPLPHLPIPIPPHPLLSSPPPLLPSPLPPLLLPSLPPLLSPSLPLLFSPPCLPLKSRSFIGYWKSRDPKVAQGGESFDLSLTIPESTNHAAYMSDQPPYANYGAEENYGDLQGLTSTLPQPEADSTSAAHNHAHHQQTMYQHQMGVGGNMVHANPQFPPQNLYIPPISQPGNMGPVQTTGYMAHPGCGPPTPVYTSASVAMHGAGPPQAAHMMSAVGGMMGYYPRPQMVRSGGSPNSGGSPSPGSDDSDDSTPLAQMGRGKRPSSESTEGPARGKKPKVSKKSKKKRDPNEPQKPVSAYALFFRDTQAAIKGSNPNASFGEVSKIVASMWDSLDADHKNVYKKKTEAAKKEYLKALAAYRASLVSKGGEGEGVYGAPGYGQFAPGFGYPPTTSAPGHPQVQSSTQMSPLAKKSPLLSSLMADPPPPMMTPPMSQPMPPSGPPMMPHGSMPPMSAASMAPQAQQGPQAAHQPPTPQSHLTPMTNVPTTSPYMNQQAPGSMTSPGGGGSPVGRVQVDNSRASRDMLAAQPLVQTASGPGAQTQQYTIQNGKMSTAPMNALCLIAEMFSAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N1C8</accession>
    <name>A0A3R7N1C8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase</fullName>
            <shortName evidence="13">GNT-I</shortName>
            <shortName evidence="13">GlcNAc-T I</shortName>
            <ecNumber evidence="13">2.4.1.101</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_006857</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11456"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="Rhea" id="RHEA-COMP:14368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60625"/>
            <dbReference type="EC" id="2.4.1.101"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">The cofactor is mostly bound to the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Golgi apparatus membrane</location>
            <topology evidence="1 13">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyltransferase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.101" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01001869">
        <property type="protein sequence ID" value="ROT74632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N1C8"/>
    <dbReference type="OrthoDB" id="6345243at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003827">
        <property type="term" value="F:alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047223">
        <property type="term" value="F:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004139">
        <property type="entry name" value="Glyco_trans_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039477">
        <property type="entry name" value="ILEI/PANDER_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052463">
        <property type="entry name" value="O-linked_mannose_GnT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46396:SF1">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03071">
        <property type="entry name" value="GNT-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15711">
        <property type="entry name" value="ILEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ILEI/PANDER" evidence="15">
        <location>
            <begin position="56"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU368119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF15711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT74632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="696" mass="78121" checksum="1525666D7CFB8C8B" modified="2019-04-10" version="1">MPSFTASEFPNPRNLQIVGKSGRLTVAALTNYSDIQIPGDPSFPDIPADGVKQYSGFYIFIFNQWTGKRIGNYFHIQPWADLSYLRRFLDSLQPGRIILFVLKDDLEYGLPQEIRDLLQSLGSMAAGSIGRGMLWGWLWVKGGRTLAETLTFPTEEKTGARVLFMSSVELADEGGKTASTPSLRSSRTQPTPAGFSSSPIFSLLTFLPPHPAGSPSSPAGFSSSPTPALPPHPPPAGFSLLRRVSRVSPGGFSSGFSLLTHPPRVGEASQWCPQWPDSEPWQRRRKFCSKYEQYGDLCSCSSPNLLDFPDSKIENSQIEKAVIVVLAHRVPSLYKSLKTVAAAQGFNRSRFEVFTPAPHPELSEFLRLVGLPLTVTHEDSEFVATLITKQFVFMIEFVLRKYKDADLLIFLEEDVSVSPDFFMSVDDPSLFCVSAHNDLSYPQTSYDPRAVLRAESYTNYGWMVTRSFAAEMAAGMAHMEMEFDWDIYTFYYIRGNRECIIPEVSRSHHFGQSGSHISQYSARVLFSTKNFNQDPAALVEGVERLEKHTYENHITLLLAKAQYINVEETNPCDADFLERFSSESEVVYAIFFHGEGDIHWFRISDAWTTIARCLGVFSSDVREGHRGLYRMRLGAAHLLLVAHPVSPYSLLKPPDLPVFRATPSALAGAHRALTKDLVRDRYRLEPPEETYRRLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N7Q1</accession>
    <name>A0A3R7N7Q1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Death-associated protein kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001240">
        <property type="protein sequence ID" value="ROT79462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N7Q1"/>
    <dbReference type="STRING" id="6689.A0A3R7N7Q1"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="245"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="278"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="61"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="393" mass="40893" checksum="69C66AEF81C378E6" modified="2019-04-10" version="1">MTARSEQRPQLLYSASGTAAAASGPPLKPDKEGVASPLGEAGSALSISAAPAPGGGDEAEALGSPTAGADVEAKAASVAASPVTNAVTPTSTAPPVAAPPVVDSSSPSRLSEVPTAPPPQLHFHEEAEQKKDGSAEKSDEDASFVLSALVAAVEEGNLPGLEELFNMAQNIDVNMANKHGESAIHLACGLGQLEAVQFLVKKGGDLNATDAQGDTPLHWAARQGHAQVIAYLIEQGSQINAQNKNGESCLHVACRYGHTVVVQNLCLCNMNIDLQDEHGETALHIAVWHGFPRIVHHLCSAAANTELTDKENQTPLHVASGRGHVECGEDWCLCLAGCTVEQKSRDGILAEVSAMAQGYDDIADLLNKLRGNNNGRNTSSNSFQVHPPFSGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NAW5</accession>
    <name>A0A3R7NAW5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000876">
        <property type="protein sequence ID" value="ROT82151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NAW5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="73079" checksum="77E6029E01E08AEB" modified="2019-04-10" version="1">MPLGKRGGGVRHPRRCGQSLSLPWEIYERPREVKVHPDLHWASLSSLRRAPLSPFSPLVYRPSVSFLLVFSPPSSLFSPFLSSRLLSSFFSLSLRLPFFSLLSSFSRLSLASFFSSSLVFASLLSFFSLSRPPLSPRSLFRFPSFVSLVLPPLSSLSFFSSSLVLPLSPRSLFSPFLSLASLVLPLSPRSLLSPFLSSRLLSSSSLSSLSLIAFPSSRLLSSFLSLLALSYRLSFLLVFSRPSSLSSLSLIAFPFFSSSLLLPLSPRSLSPSFLSSSLVLLSLLALSYRLSFLLVFSRPSSLSSLSLIAFPFFSSSSFLSLLALLSPFLSSRLLSSFLSLLALSSPFLSSRLLSSFLSLLALSSRLSFLLVFSRPSSLSSLSLLAFPFFSSSLVLPLSPRSLFSLSSSSFLSLVFSPRLPRLLSLFSPSLSSRLSRLSLSSPFLSSRLSVSSSLSSSLSLSLSFLLVFSPPLPLFSSLSLIAFPFFSSSLVLPLSPRSLFSPFLSSRLLSSFLSSLLALSSLPFPFFSSSLVLPLFSLFLSPFLSSRLLLLLSSLSPSFPLTLSSRLSSFGFLSSRLLSSFLSFLAFPPSVSSLPRLPSSLFTRPRSFGLLSPGFPPFFRLLSFPPWSLSLLFVLPVLTLPPRLPSTQVPLCSFAPSPSHPLLPHFSSSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NC54</accession>
    <name>A0A3R7NC54_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PWWP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000721">
        <property type="protein sequence ID" value="ROT83197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NC54"/>
    <dbReference type="OrthoDB" id="10013064at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048795">
        <property type="entry name" value="PWP3A_3B_4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20886">
        <property type="entry name" value="PWP3A-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="542"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="679" mass="78069" checksum="738CC3EA2ECF4251" modified="2019-04-10" version="1">MSEKLVAPSGSRNPSCVTNEDYLSRPRGKMWPEVGEGERIIVRAEVKAEFDTDLGKENLHYTEPASGLHENKDYLQDKQLESETNKHLTLKATVQEYPTGELTKEKEQSNTFTVSHTLSSVNTLTIDFKNPKRDILESTNDSKNTYISDVANKVEYDLEDIDSVDKEASERTCSEGSRLQSDVRTKANLADSQGGELGIEINVRTQNEKLNSEKSEKSEKSGEGESIAYHFKESRVDKQKGKNGNRSMCTWESIKMNRRRSERIQGRDERVERPNEGIEGKREVVKSPCQKLLGDKMEYNKDMQYKKGGAKRQLVKDKTSDMFSWKKCKKKKENSPQNIPEDLNENLMDIDDDDLPDLTACQAVKETPKVEIQVNDLIWTLHRGMWWPSYVKAKYGRDKKVSVFFIGCSQAVAIRVRWTNTRPFISDHIPPCVDESAQGLSELCKSFSQLRENRSDITPHCFFSLPVEKQNALMNANSTSNEDLRSPSISRKTTSGREETPKLRKRHSLSGCMGSKEKGNTASKELVMSSRDKQKLKVAILARRRENEKLLRYIRSQECISHLWKIFSGEKASKRHDMYQEECSRKMLMWSGVGPFHLDEEDEQILEVIDFLHKELCSKRQDFALAHDYALRVWMPEAIKEALRVVRKVPETELENALDTGYRETQTEKKARRLDFSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NDM8</accession>
    <name>A0A3R7NDM8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RCC1 domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000558">
        <property type="protein sequence ID" value="ROT84351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NDM8"/>
    <dbReference type="STRING" id="6689.A0A3R7NDM8"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052830">
        <property type="entry name" value="RCC1_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46849">
        <property type="entry name" value="RCC1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46849:SF1">
        <property type="entry name" value="RCC1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="193"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="30286" checksum="575C5ACB374AC0C9" modified="2019-04-10" version="1">MALVACGLNANGQITPAGPPLLCCPTPVRDKKDVCEVHIACSHILWKTNAGWQITGYRNLDYSLEEEMAQGWKISMSEMRMAAINDDGAVVLREKGQWRKLFFQRDTAMDSRNLGPSVQQVEDQDRIAESESNVHHTTSQIKFSSVFVEDNSLIALDEDGKMYSSGVPLPYGGSRISVVEVGKEHCMALTTDGVVLTWGSGMRGQLGNGELCQIDRPEPVESLQGITISSIASGGWHCVALSTSGDAYMWGWNESGQLGFPAKADQEASILGTFSHRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NR62</accession>
    <name>A0A3R7NR62_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003242">
        <property type="protein sequence ID" value="ROT64507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NR62"/>
    <dbReference type="STRING" id="6689.A0A3R7NR62"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="562" mass="59061" checksum="37D67853CD337673" modified="2019-04-10" version="1">MIRLLPRSTYHSILSRSVNPLVSSLVSPPLLPSSAPSLLFLSSPSLSSLPSPFLSLSLSSLAPLCLSLPSPPSSPHYILSFPSLLHARVPPRVTRPTNPCPLTLPLLSSSSSLPLLESLSSNPSPLHLSSLLPLLLVDLPSSLLSALAPLLSPSSVSSLKSHLHSLLCLRFPLNVVLSSLRSSPLSLLTFPLDSSASPSLSTSPSPSLRSLPSSPSSYCLPGLTSPSPSSSFLSHSLFPLPLVSPVFTPPLYSPSIHYSSLANRPQASRSPSIVTLPSALCLLVLYVPVPSRALHPSLPSPFGSLSLFLFSLPSPPCTPLSFSSPLLLSSTHPHLSSLLSLPRPPSHPFSFIPSSSVPPPSFSILSPYSQILISPRYFPLSPSSFATSPQNTLSYSYSSSILSPHTSGSAISPLIFGTSLLRSSSGLASCPLVKTAIIPSPFFPSFPSSPSSSFPFISLSPPLFPPLSSSHTPLFSLFPSFPSSSLLAVLSLIAPSLLLSSSSSPSPPLSFFPSSPPLPSTLTHLILLSSLRYSILPWLPPLLSSLLSLLSHFASSSLHDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRP9</accession>
    <name>A0A3R7NRP9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative huntingtin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017139</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in microtubule-mediated transport or vesicle function.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the huntingtin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003168">
        <property type="protein sequence ID" value="ROT64934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRP9"/>
    <dbReference type="STRING" id="6689.A0A3R7NRP9"/>
    <dbReference type="OrthoDB" id="10065698at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048411">
        <property type="entry name" value="Htt_N_HEAT_rpt-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028426">
        <property type="entry name" value="Huntingtin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024613">
        <property type="entry name" value="Huntingtin_N_HEAT_rpt-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10170:SF10">
        <property type="entry name" value="HUNTINGTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10170">
        <property type="entry name" value="HUNTINGTON DISEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12372">
        <property type="entry name" value="Htt_N-HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20926">
        <property type="entry name" value="Htt_N-HEAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="466"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="466"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="476"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="805" mass="86864" checksum="1808EA6055EA7D11" modified="2019-04-10" version="1">MAALEKLVRAFEAVKLSQGNPASGGGSVPGGSSQGLDQRPQEHTSTMASLASSLSQQSQGLLSKKDQVLSTKEKAATCTVIADALVGAKSTDIQKLLSVGIETLLLLTADTDPDVRTNANESLNRVIRSLSETQLGKIQVELYKEIKKNGSVKSLRAALTRFAALCHHIRPQKGRAYVQNLLPYITRMARRTEEPLLETLASSLEKIMPVLGHFTNDNEIKNLLKAFLHNLSSTSSAIRRSAVTSLIVLCCHSRKPPMFFGWLLSTILQILVPVQDDIPTSQVLGCLLCMRSLMPHIWEQCSPSLPSEGQQSQHSTQPQSSDYAISYDQTLQVYELCLHYSSHSDHNIITASLEALQTLLQNPPLALLMTLTAPEGITRSRIFADPRASQLSSRAPSQISVAPSLYEEDSLLLDLEGGSGKVSIDIDTPDEVDADENDSSLYSSIEIGKVSGDASLLFGRGEMDLNGEKRNGDREKRKHIQHISSHSHNKSLDDKAMGTDKAGGAIGSFLDESLPIRYLVRYLSSSFLLSGHVGSLIPDQMVRVSIKVLALNCVGLAVTVMPSLMAEPLFTTSGGETELEQHIDDILRFHRHSDPQLGASVGTVVGQYIRASLIHGCGQYNDLGRPGLALPSLLEILCKLLGSESSVTSRGAVSGLGLCLGELLHSWHAGVVLAVLPHLVNTGSNLYWLVKVELCDLLAGLPLSYIDHVESSSTYTSAGGAVAMMSSLRQSDRFSHRVLTAVLIPLLADQDPRVRTAAGTACMKLVPELMSSGNLIQKVASNLVRPGRLVPSKHQSSGTPQRKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NST0</accession>
    <name>A0A3R7NST0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_016222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003036">
        <property type="protein sequence ID" value="ROT65798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NST0"/>
    <dbReference type="OrthoDB" id="5565075at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018717096" evidence="2">
        <location>
            <begin position="16"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT65798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="443" mass="51812" checksum="EA05CFC19178DCD1" modified="2019-04-10" version="1">MRLFLLLLLVALAVGAYQKADQNGRHDQDILDLTAEDTALDRRERQVKPDKRNTAKEQTNKEDNSLKLNVKRTKYTMDGNGDNKSERGKKERPPKQVEMIDKIKKMHNKNREESEPKEKRKKAQRQESRAKKRKQQKRRQRGQQNDRKEDRKNKGDRKHSGNKNTKKDKKENKDKGEKDDGNKNGNGRGTKKQGKKYNKGNEKRGQNRDRDRSRKEENRDKDRSRKEEKRDRDRSRKEGHQGEERNRKDKNQGKGRSRQEEKRDKDRSRKGENQDKQKGRKRQNQDKFNAKRTKQQKEVSEGRQGKATEEEKEVKPSSRSETNIIKGRNLHNGKDKNSEKINRPQSASKNIARNTGNIGSEIGFFCPFFNLNSKGCKREQLKFRGKVNGKKQNKKYCKLDAPDGVIISTNKLSMEFRRKQFKSDEFSGGFLCEIYTVGGMAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NV62</accession>
    <name>A0A3R7NV62_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RFX1-4/6/8-like BCD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002797">
        <property type="protein sequence ID" value="ROT67587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NV62"/>
    <dbReference type="STRING" id="6689.A0A3R7NV62"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057321">
        <property type="entry name" value="RFX1-4/6/8-like_BCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25340">
        <property type="entry name" value="BCD_RFX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RFX1-4/6/8-like BCD" evidence="2">
        <location>
            <begin position="55"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="44959" checksum="0D2060BE74ECA1F5" modified="2019-04-10" version="1">MKFHSSPQILTLIQTPLPYYLSFPFFTSFLSPLSLHPHLILSVYTPYLSPVIPPFSSAQIQSFLVHFWQGIPPHLVSILGTNVLVNLVGVCDSILYRAVCSVLMPSVLQSLSLILLSTPPQFVSPALIFTLFPSSSSSFFLPSSLGPLLSFSLASRSDLLCSVDCLSGRRSLLLLISGSTSISRSLLLLRARPRGRVPGAADLETRARQLRPSTSHREHAAQPSAFALRPSVFGPLLYPRLFGHLRTITVNYVTAQDTQPRHLQLSKRGLSHDVVSSSILSPSSLIHSIRLTPLTPFSFLIHLIPLFPYPLYSFSLSSSTLSLSSLIQITPFPFPHPPYPSFPLSTLILSSLIHLSPFFPLSTFSLPSPTFLHSPSSHPPHRPILISAQSSTLYQVPTRLTATPQHHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NZU6</accession>
    <name>A0A3R7NZU6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Endonuclease III homolog</fullName>
            <ecNumber evidence="13">3.2.2.-</ecNumber>
            <ecNumber evidence="13">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <shortName evidence="13">DNA glycosylase/AP lyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NTH1</name>
        <name evidence="16" type="ORF">C7M84_010276</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="13"/>
    <dbReference type="EC" id="4.2.99.18" evidence="13"/>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NZU6"/>
    <dbReference type="STRING" id="6689.A0A3R7NZU6"/>
    <dbReference type="OrthoDB" id="2099276at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1670.10:FF:000003">
        <property type="entry name" value="Endonuclease III homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000005">
        <property type="entry name" value="Endonuclease III-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03183">
        <property type="entry name" value="Endonuclease_III_Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030841">
        <property type="entry name" value="NTH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00764">
        <property type="entry name" value="ENDONUCLEASE_III_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="HhH-GPD" evidence="15">
        <location>
            <begin position="164"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT71400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="45149" checksum="19C33CDF2C162FDE" modified="2019-04-10" version="1">MYQEEFFKNFWPNWSNYNPYAFSGQAIGATAGYSGWGTHGHPAHAHGGAMNDYRQMVEDPMLPSYAMAPFSRRHISIQYEDQTRMVGQQKVEDCLMASQESSSDQYKPLPPGWEPPDWREVLENIRVMRSARDAPVDHMGIQKCMDDDAPPEVRRFQVLIALMLSSQTKDEVNHAAMTRLRAHGLTIDNILATDDETLGQLIYPVGFWRKKVMYIKKTCKILKNEYGGDIPSTLEEMRKLPGVGPKMSHLCMSLGWGKLSGICVDTHVHRITNRLGWTGETTKNPEKTRLALESWLPEELWAETNELLVGLGQKICLPVSPKCSQCLNVQLCPYGRNPVNRSPRKRSPPKHPVETGPPAQQLVSYYGMKPAQVFNTNSWSAFSSYDQRRTLTDCVVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P0J8</accession>
    <name>A0A3R7P0J8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative F-box-like/WD repeat-containing protein TBL1XR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_009607</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat EBI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002215">
        <property type="protein sequence ID" value="ROT72027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P0J8"/>
    <dbReference type="STRING" id="6689.A0A3R7P0J8"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000001">
        <property type="entry name" value="F-box-like/WD repeat-containing protein TBL1XR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000014">
        <property type="entry name" value="Putative F-box-like/WD repeat-containing protein TBL1XR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="233"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="316"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="358"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="409"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="485" mass="53008" checksum="720A6C56A6A29CBA" modified="2019-04-10" version="1">MSFTSDEVNFLVYRYLQESGFYHAAYVFGIESHISQSNINGALVPPAALLSIIQKGLQYTEAEISIGEDGSERLIDSLSLIDAVMPDVVASRQQQNQQQKAVVKTEIPSTNGDEGTTGENMDVDNSVEIPLNKATILRGHESEVFICAWNPTTDLLASGSGDSTARIWNMNDNNSSANQLVLRHCIQKGGTEVPSNKDVTSLDWNCDGNLLATGSYDGYARIWMTDGRLASTLGQHKGPIFALKWNKKGNYILSAGVDKTTIIWDASSGHCTQQFAFHSAPALDVDWQSNNSFASCSTDQCIHVCQLGENRPIKSFQGHTNEVNAIKWDPQGNLLASCSDDMTLKIWSMRQDTCVHDLQAHSKEIYTIKWSPTGPGTSNANMNLILASASFDSTVRLWDVERGACIHTLTKHSEPVYSVAFSPDGKFLASGSFDKCVHIWSTQTGQLVHSYKGTGGIFEVCWNSRGDKVGASASDGSVFVLDLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P1T2</accession>
    <name>A0A3R7P1T2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002075">
        <property type="protein sequence ID" value="ROT73051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P1T2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="616"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="647"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="726"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="804"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="848"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="874"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="905"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="975" mass="104109" checksum="99C757093652912A" modified="2019-04-10" version="1">MTPGAAAEKTGARSSLPPSSSFSLGLPWLLPPLSLSVFLGSSLAPSSSSFSGSFLPLFSLVFLGSSLAPFLSFSLGLPWLLLGSFPSFSLLPCPPWLLPPLSFSSSLAPPGPSSFFLSRSSLALLGSFSSFSLGLPWLLLGSFLLFLSRSSLAPSSSWSSSLLGSFLLFLSVGSPWLSLAPSSSFSLGLPGSSLAPSPLSGLPWLLLGLLIWLLPPFLSLSSLAPPLFLLFLSVFLLLGSFLGSLAPPLAPSSSFSLGLPWLSLAPSLSLSVLGSSLASFLLSSLSVFLGSSLAPSSSFSLGFLGLLLGSFSSFLSSSLISLPWLLLGPFLLFSLFPWLLGSFLSFSLGLLGSPWLLFSLGLPWLSLLFSLFSGLSWLLLGSFLLFLSLFLALCPSSSFSLAFLGFLLGSFLLFLSRLPSLGSFLLFLSRSSLAPPWSFLLFSLGLLGSSASFSFSLGLPWLLLGLLPPLSLSSSLAPSLLFPLALPCSLPCSFLLFSPTLLSSLPPLLSLSALPLSPHLILPPLSLAWPPPPLSLASPLSSSSFLAFSSGLVFLAPPWLLPPLSLSVFLGSSLAPSSSFSLGLPWLLLGSFLLFLSRSRASSPPWLLPPLSLSVFLGSSLAPSLSLSAFLGFLLGSFLLFLSRSSLLLLGSFSFSLGLPWLLLGSFLLFLSRPSLAPPWLLPPLSLQEETKARSAFLPLSLACFLLSLSLASCLSLLFLSLASSLPSFFLSLLAFLSSFSRLPPSSSFSRLPPSSSFSRLPPSSSFSRFSPFSWSSSFSRFLPVVLSSLTPPSSFSRFLPFSWPFPFSCSSPFSNFLASFLLFLSLLPGVPPSSFLLPLSVFPFLSLPLRPLTLISLFLFSFFLLLSRSILHCFFFLFLCLLSLFIISHLPISPSFLDSYTSSPISFSSLLSRISFDIIAVVNSIRRKERRVTWVVNLSTLSRVITLVLMMSEGIEGMPGYAACEYACKYIRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3B8</accession>
    <name>A0A3R7P3B8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL21</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L21</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_007223</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001915">
        <property type="protein sequence ID" value="ROT74290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3B8"/>
    <dbReference type="STRING" id="6689.A0A3R7P3B8"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT74290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="163" mass="18559" checksum="5008C52A28F55C79" modified="2019-04-10" version="1">MTNSKGVRRGTRNMFARGFKKNGVEHLSTFLRVYKVGDLVDLKGNGAFQKGLIHKAYHGKTGRVFNVTQHAVGVIVNKRVKGKILAKKLNVRIEHLKHSNCQVDFKKRIKENEQRRIEAKKAGVKIPKGELKRKPALPRSAHRVNITKNKPEFLTPLPYEFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P902</accession>
    <name>A0A3R7P902_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_017882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003304">
        <property type="protein sequence ID" value="ROT64192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P902"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT64192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="560" mass="64901" checksum="D99BC05CEFD34A62" modified="2019-04-10" version="1">MVSRRLHRGWFPTSSQRVVTSSQRVVSRRLHEGPDVSPRVVPDVFTRWFPTSSRGWFPTSSPRRGWFPTSSQRWFPTSSQRWFPTSSPRVVPTSSQRVVPNEGGSDVFTRVVPDGGWFPTSSPRVVPDVFTEGGSDVFTEGGSRRLHRGWFRRLHEGGSDVFTRVVLFTEWFPTSSRGWFPTSSQRVVPDVFTEGGSRRLHRGWFPTSSQRGFPTSSPRVVPTSSPRGWFPTSSQRVVPSSQWFLFTEGGSRRLHRGWFRRLHRGWFRVFTEVVPDVFTGWFRRLHRGWFRTSSQRVVPDVFTEVVTEGGSRRLHRGWFPTSSQRVVPDVFTEGGSDVFTEGGSRRLHRVWFPTSSQRVVPTSSRRVVPTSSQRVVPDVFTEGGSDVFTRVVPDVFTRVVSRRLHRGFLRVVHVDVFTEDVFTVSFTEGSRRLHRGWFRRLHGSRRLHEGGSRRLHRNLDVTEGGSRRLQRVVLDGGWFRRLHRGWFRRLHRGGSVFTEGGSRRLQWGIRHFHVFSDVFTEAGSRRLYRFCFPTSERDGSRRLQIDWFPTSSKDGHRGIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAB7</accession>
    <name>A0A3R7PAB7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative neural-cadherin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016917</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003137">
        <property type="protein sequence ID" value="ROT65134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAB7"/>
    <dbReference type="STRING" id="6689.A0A3R7PAB7"/>
    <dbReference type="OrthoDB" id="6252479at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00110">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001791">
        <property type="entry name" value="Laminin_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050372">
        <property type="entry name" value="Neurexin-related_CASP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036">
        <property type="entry name" value="PIKACHURIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15036:SF85">
        <property type="entry name" value="SP2353, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00008">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02210">
        <property type="entry name" value="Laminin_G_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00282">
        <property type="entry name" value="LamG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50025">
        <property type="entry name" value="LAM_G_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="198"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="4">
        <location>
            <begin position="252"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="522"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Laminin G" evidence="4">
        <location>
            <begin position="563"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="655" mass="69043" checksum="069A7FA62283430F" modified="2019-04-10" version="1" fragment="single">MAGDVSLYHQTVEIRISYELGFKVNDASQGQTGVNANVTVKVTSLSQQVVSAATPLTLAADPYYVGASSILDRLVVAARAWVEGSSEGVQAVSVQKVDGPSAPSTRVWLTSPGVSNLDHVLLHRKDELEHTIGVSITDVGVGTCEEAAQEDLGCSEGCAAQASVTSGFSVVDANTSAVVGPWVGVHSGCGCARFAPADDTVCSADTCLNGGHCVPTPTGTRCICPHGTFGSRCKILSRHFEGGGPGGETGGRNQMEEDLGGWAWVPSIPSCAEVHLSLEVLTGSPDATLLYSGPDHLPPAQGANSDMLALELRGGRPSLLLDLGAGPAALSLNASYSLADSTWHRLDLIWKDELVEMIVDLCSGASIDGPPAKSSKSALNDSETPTSSPPIPPDAHTCRGAARLSRGALLLNAAQPLQVGGLAHPPPAHTVYGWPKPILARPLRGCVRNLRINGEHPPPPPPPHPHHPPTLPQQYPHPLRPPHVIFHSVCLLSVLSEAVFFVFQLIDLGHGLLGQKSSPGCKSADCLASGISCGVHGRCHGSPGYLRCECQPGWSGPDCATPSTPTAFQVNSYVKLALSFTPLAYTTTVHLRFRTWQRRGELVVLSSQHGRDRFAVQLDNGRLCLVLQLHPDPQRSLCLTRAQVTDGQWHTVSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBL3</accession>
    <name>A0A3R7PBL3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003000">
        <property type="protein sequence ID" value="ROT66031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBL3"/>
    <dbReference type="OrthoDB" id="6382835at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018718002" evidence="2">
        <location>
            <begin position="18"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="133" mass="14913" checksum="311467D4ADFAAF45" modified="2019-04-10" version="1">MFARIAAVLALAAGAMAAPTANIPLFALARNPDYTPPPYQIPIRSHDPEPYEAPEDRPVQEIYTEPQRLQVPATYVAQQPYQTEQRYPDVRHRSSAPAYGPGSTDESPRSYQPAYTFRSLNIPPVRHSSPLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBW7</accession>
    <name>A0A3R7PBW7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004495">
        <property type="protein sequence ID" value="ROT60901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBW7"/>
    <dbReference type="OrthoDB" id="6107927at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051560">
        <property type="entry name" value="MAM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282">
        <property type="entry name" value="APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282:SF101">
        <property type="entry name" value="MAM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="67"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="240"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="404"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="601"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="752"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="2">
        <location>
            <begin position="916"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1122" mass="122949" checksum="F6364B1538E192F8" modified="2019-04-10" version="1">MPPSAEGQTWTKSPTRCRSYRVLNFKTDTMIASSSVTPPDAAPAQLPPSSLSPETTTPGPVIPPAVLKCDFEDAEKPLCDFKQDSGEYDGLWNRVDASSPPSPLHPGVDHTLHTGAGHYIAAGMQEGSPYNQTTARLKTPRMDNTLEYCLTFFLHHIGDRPPPLIVNVEAWDGPQQVELLRRESSLHDTWVFVERDIPAGFIEANFLISIEARLSTYQDGDASLDDLKVSQGRCPNHDGMSCSFKQGLCGYEQEQELDDLDWLWHDGKGDDDAFLPVETHWHFYYAYLNTSAPQGSSGVMYTTEIRLSSPHCMVFNAHIHAEKGKSAVLEVLNVGEGTIADGQLLDRFEDLGPDWATLQVMLPPSERPMRLAFQGIIPINENFEHSTLAIDDIFIRAGGCDPPGYCTFDGYLCTWFNNEHMGSLVWESSGPGDLSLETRPFVDSTQRDHSGGFMFIEADEALSGEKAWLMSDRLAASGPHERCLIFWYHMYGAKGTSLSAHTYWEEFGQVTTLWGLRPTEARWDSGWQYAAAPFSNYVPIQLVFEAVLGSGFMGDVAIDDVLVASGGCALQPAEAKSGVNYTTPVLPTLEPPATSSPDMMYDCSFDENDLCAWTSDASEGTGNQILWQVATDQYSGGYAFLDVAGEDLGRGARGTLVSPPISGTAGSCLSFSYILDGLHELNILIMKETDLEEVWHVIGPIGTVWKDAHITVSSDAVYQIIFEGVRGDINKNSTHQTCQKLLTDYFSLLAEDLCDFEGGHTCGWHPATSLGPGTPCWELADGQYSHGDHTTGVSKGHVLKATNTWSSDENTALSNSSFYVSLGMSCVSFWYFSQPSTSVVIELFAVGESLDGGLVPPENIFGMPAGRLDEWFFVRIPVSYKLFRLQMSATFASPDNTSAVVVDDFRVQQGTCGLPGECNFNEGDLCGWIPSRTEKAYWEVIAGSDHTYGDLGGGLLALKAENHEPGDLAVIRSPPLGPFTATSLCMQLWVSMEEIEEGTLRVYVEPIGEEKVLVWSLSNSVQPGWQLGRAPLYNVTTGFYQVVLEGVLGVNQLDVLRVDDIMMFYGPCGIWPKKATPGAGTTTTTTSLPPISTTTQALEVRKWVQTRMASSAYELVVYGPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PC68</accession>
    <name>A0A3R7PC68_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GOST seven transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_021136</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004342">
        <property type="protein sequence ID" value="ROT61119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PC68"/>
    <dbReference type="OrthoDB" id="19932at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="7">
        <location>
            <begin position="284"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="524" mass="58636" checksum="A624246E302433F7" modified="2019-04-10" version="1">MNDMLPGTECLLPRRVSDAAASPPSLFLPSFSPHLHSSLPPPHPTSYSLLTPPSPYFLLPTTYFASPYAPYSPYFPILPILKTPISLTLLPLPPTKHSPLHQTSQPYSFFSPPPIHIPSSLSPFLPTLTLSPLTNPLPSTSSLFPHLTLSLPPYPPSGGRVDRSLLALSTKPPCEPSPSPLSLIRIMQSGPQGVCVDLLLLLLISLLLLLLPFLLLLLLLPFLLLLLLLVLLLLLLPFLLFFFPFFSFSFFLFFSSFFPFSFLLSFLTHSLGTLWPKKVDMNCMLEKAVFTAEYSSINQNGYSVPGLIILAELASCAKRTLARMLVIIVSLGFGIVKPRLGVILHRVVGVGLLYFVLSSIEGCTRALQSRSDPQKQVLLASLPLSLLESAICLWIFTGLVQTTRILRLRRNLVKLSLYRHFTNTLAFAVIASVIFMVWSIRYHQFEKCLTDWKELWVDDAYWHVLFAVVLLVIMILWRPSNNNQEDDLKWVEENIPSSIADSALPILDSDEEIVTSKFEISKMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDA0</accession>
    <name>A0A3R7PDA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative carboxypeptidase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_014672</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002828">
        <property type="protein sequence ID" value="ROT67268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDA0"/>
    <dbReference type="OrthoDB" id="3626597at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000084">
        <property type="entry name" value="Carboxypeptidase B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705:SF140">
        <property type="entry name" value="FI02848P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11705">
        <property type="entry name" value="PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00765">
        <property type="entry name" value="CRBOXYPTASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018792676" evidence="11">
        <location>
            <begin position="21"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M14" evidence="12">
        <location>
            <begin position="122"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT67268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="369" mass="41226" checksum="557B518E0CA06F72" modified="2019-04-10" version="1">MRLWAGLCQLVLAAAALGQAAGPAADRAYAGWSVLEVTSPAALVHAEGWGRPGHVTFLSFDRQKGSTILAVSQEELPHFAQKLTDGGLTFGVQSRDLSQVLVSPLPYAQLGELPKGVATFDRYMKYEEIISYIEELPNNYPDQVHLEELGRSDEDRPIYLLTINKNNSTRKNEKNVIFIEGGMPCNRGRTRGVVSPASALYLVERLLESPSLLRNAEWRLVPLLNPDGYVYSWNHDRLWRKNRAPSSDPECYGVDLNRNFAYHWGEVGSSSEPCSFIYQGPQPFSEPETQALRDAVLEVQDRTKAYLSLHSYGQVFLYPWGYTRTVNHSRTAELVKMAEGMARRIKAANGTDYTISGSTSACKLHIELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PDT1</accession>
    <name>A0A3R7PDT1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000748">
        <property type="protein sequence ID" value="ROT83040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PDT1"/>
    <dbReference type="OrthoDB" id="6394174at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="135" mass="14277" checksum="B9C0F7AFD6D61656" modified="2019-04-10" version="1">MRNLGSVQAPTVPTLLIKSPEVGGGTRGSTTDSPSQRRGHADSSTKTLRSVKTSTSNTTGSSTPGYGYSSSHKPVMVNGPSVKALVTSSANTASPTLRREAATPSLLLPGRRRRGLRVRQRLCPDVCGNLEKWCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF43</accession>
    <name>A0A3R7PF43_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000505">
        <property type="protein sequence ID" value="ROT84727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF43"/>
    <dbReference type="STRING" id="6689.A0A3R7PF43"/>
    <dbReference type="OrthoDB" id="10263222at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090730">
        <property type="term" value="C:Las1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007174">
        <property type="entry name" value="Las1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002:SF0">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="343"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="405" mass="44570" checksum="60CA589DD7260CA8" modified="2019-04-10" version="1">MVRKNKGRESAGKDERLWVVPWFSKEEWIEVYKATFSDDVKKWKHAFGTMTVWQSRLYRTHIGIAVTRHLLQAKILDSDPAASQELKSGANAIAITKFVSTIIKIPAERYPPNESQSQVPYRAREDWISLPTTEEERNTTDTKAPSDTAEETTQSTTNTPKKPKPATPQGIKPWDFAVEQLRRYCREILEKPRPMFSLLTEVLHAVQDKYEENPQECIDTLISILFLPSYVTNSSLPLPHSSPLPLSPSSSLLPSPSPLPHSSPLPPSHSLTPPSPLTPLLLTPSPFLPPTPHPLIYTCPTSSLSFPFPLLLSSSPSSSSSSSSTPSSSTPSSPPPPIPFPTSTPHTHTSLPCPSPPSFKPPHPPPPPSTHPPLTLHIPFPTPSTPPSLITHPPIPFPTLYPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKK6</accession>
    <name>A0A3R7PKK6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Platelet glycoprotein Ib alpha chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002546">
        <property type="protein sequence ID" value="ROT69592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKK6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="552" mass="65791" checksum="BB3062257864DD14" modified="2019-04-10" version="1">MKTLPIPEEKTLPIPEEKTLPIPEEKTLPIPEEKTLPIPEEKTLPIPEEKTLPIPEEKTLPIPEEKTLPIPEEKTLRYPKKRLSRYPKTSPEPEEKTLSRYPKKKDSPDTRRKDSPDTRRKRLSRYPKKRLSRYPKIPEKRLSDTQEKTSPDTRRKDSPDTRRKLSPIPEEKTLPIPEEKDFRYPISRYPKKRLSRYPKKNTEEPPDTRRKTLPDTRRKDSPDTRRKTLPIPEEKTLPIPKTPRYPKKRLSRYRRKDSPDTRRKDSPDTREKTLPIPEEKTSPIPEEKTLPIPEKDTRRKDSPDTRRKRLSRYPKKYPKKDSPDTRRKDSPDTREKTPDTRLSRYPKKRLSDTRRKTLSDTRRKTPIPEEKTLRYPKKRLSDTRRKTLPIPEEKTLPIPKISDTRRKTLPIPEEKTLRYPKKDSPIPEERLLPIPEEKLSRYPKKRLSRYPKTPDTRRRLSRYPKKKEERLSIPDLPIPEEKTLPIPEEKTLPIPEERYPKKRLSRYPKKKTLPIPEVKDSPDTRRKDSPDTRRKMPRSVKSPFPSDSANMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPU5</accession>
    <name>A0A3R7PPU5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002036">
        <property type="protein sequence ID" value="ROT73328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PPU5"/>
    <dbReference type="OrthoDB" id="6347961at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052058">
        <property type="entry name" value="Alcohol_O-acetyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28037:SF1">
        <property type="entry name" value="ALCOHOL O-ACETYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="55998" checksum="BD8C0D9B5AD3491F" modified="2019-04-10" version="1">MLATRFGRLLRPCRLVISSSNKTKFSSGSGTQSHEVENGREFKWLWPAYREEEMFKAAHDIGCKSLIVCYRFNTVKPLDPGHVEQALRHFQRKVPNCRGFFKERDGKLWVCEDPNPDVDFECLEGAESSAIINEHINKPFRGDRSPTWKARLVPVPADAPCAMPEIQAAFPHQYDLVFMPHHSFMDGITIALSTGKLVGLLNDLIAGRPVNDEPFGVYLNNEEIGKIDEGIAKDLEKEPEKLESAKQEILACDTPPILCKAFPPPGGKPATKFVNQIINQKSLASFTAKCKANGVTFNSGMEAVINTAIIEMVREAGVEGESHHMSINLATDLRRYMKRRPLPIYGLHVRPTVHRIETPFDVRDNFWDYTRKFHQRLSVLLKSGDALQQTVVREMTLPQLPPVEYHAAGPKPLRDYGLTNVGDLTPIMPGVGEHLQQTSVSMFGCTHFFGFPMFHQIYSFRGHMPYTIGYDTSYISKETAGALMDRIVTLMHDLGTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PUQ2</accession>
    <name>A0A3R7PUQ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000730">
        <property type="protein sequence ID" value="ROT83137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PUQ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="722"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="734"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="754"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="769" mass="90133" checksum="5435CBA6C65362EC" modified="2019-04-10" version="1">MWLEDTRERGLGIAPQAPCKVRHVLLSVKIPNILSPLEETVHIQRPTRPLPPSPTRRQKLQTTRESPDHERQAQTRHPQHERTSPDPRENKPRPRETSQTTRETSPDHERNKPRPEGTSPQPRENKPATRDKPHTRRRTSRRPRRDKPRPRENKPDHEKKKPQRETQTTREQAHTTRNKPTHERDKPRPRENKPRPRGNKPRPRENKPRPRENKPTPRENKPQTTKKTSPDPRENKAQATREQAQTKRRKAKTTREQAQTTRRRTSPDHERTSPDENKARPRENKPRPREEQAQTNKRTKPKTTREQAQTRENKPRPRGNKPDQRENKPTTRQQARPRENNLELRTYSRPRGKQGQPRREQAQDHERKGPQTTRENPTRRLQTTEQPRPRETSPDTEEQARPRETSPEHPRDARPPRDKPTPSRRTSPDTKRNKAQTTREQAKTTREQAQTQEQPRPREEQVPDHERTSPDHEEQAQTREDKPRHTRNKPQARENKPGYGEQAQTTGEQAQNLRRVTSPQTAREPTQTTREQAPPTREQARPGRNKPTTREQARHERQARPRENKARPRENKPNQREQSPDQRERQAHTRENQARPTREQTQNTERTSKTLEGTSPTTRETSQNHEGTSQNHEGTKPNREDKPQIHEGTSPAHERTKAPGYARTSPGPRETQAQNHKRTSQTREKATPREKAQNHKKETNPDSERTSQNPENQAQPKENKAQTTREQVQTTERTASDHEGTSQTNERKAKTHTRGTSGQRTYTREQAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PV05</accession>
    <name>A0A3R7PV05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000688">
        <property type="protein sequence ID" value="ROT83399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PV05"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="41859" checksum="C53750BEA6D309BC" modified="2019-04-10" version="1">MSNTYETDSTRGKYTKREKILSFFSSSYPCLPLLLLSLSSSSPPLIPVPLFSYPCFPLLLLSPPSSSPLIPVFLFSSLLLSLSSSSPPFYPRSKTLHFYPSSSSFFLLLLLSSFPSPSLSFPSPPSTSFSPPPLPLPPLLLSPFPFPLPPPPSPLPPLLPLFLLLLPLPTRHTPPPKGLQDMGERHEIGGSIYLGKYHQLKLPGADGGCDVTANGSPSSPSFSSSCLLLLLLFFSSLLLLLFFSFLSSPSSLSFSSPSPFFFFLLLLLLLLLLLSSPSSFSFFFFSSSLSSSPSSPSPSPPSSFFLSPSSSSSSSSSSSSSSLFFSSSSFFFFFFSSSFLLLLLLPLLLLLSFCFYFFFFFLCYSLPSCVAPFFFSSYSSTNSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PV40</accession>
    <name>A0A3R7PV40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Collagen alpha-1(XVI) chain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000677">
        <property type="protein sequence ID" value="ROT83487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PV40"/>
    <dbReference type="STRING" id="6689.A0A3R7PV40"/>
    <dbReference type="OrthoDB" id="10037288at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030020">
        <property type="term" value="F:extracellular matrix structural constituent conferring tensile strength"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050149">
        <property type="entry name" value="Collagen_superfamily"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023:SF1112">
        <property type="entry name" value="COL_CUTICLE_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24023">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="556" mass="58915" checksum="FCFABFD7270E3955" modified="2019-04-10" version="1">MYFFHRGGGGEGNSKGKGYKAGEGRSVREAGHRGREGARPCNLAVAPWHRGKLHGVRGILPPPVLSPLIWDPREAETAMRVREWAWRAWWLSVCLCLAAPAWAAKKKGGKKSRKKDRPVGPPPTPPAQGSPRNRTGGDNVDQLDRLLADLEPSVHFKRQYAQCPYPPTPVNPPVCPMPPACPMIPCPVPPPIVPVPPTPGPVPPPIDPVPPPVCPPAPQCPPCPTQPAVCPPGRPGPPGPPGPPCTGPPGQPGPPGISSPGPPGPPGLPGTCSGGGCVAPPSCGNEGWYGTITNMISSGCCDRGCPEGDKECPWDISLLVSKYLVVREQIDLISKFDTRIDLLVAAIFRMRLAVEGAYEMVGEPGEPGDEGDPGAKGDRGPAGEPGRCPGSSCLVGPPGDPGPPGSPGDKGRKGDCCYGTPGQRGRKGDAGRGIPGDRGPPGLRGDKGEVGRIMLGYASDPSLSNPRHPRRTRASRGQRGQRRGWEDHFRLLSRAGGVRRGYLGRIRFTPRFQLSLSALHQSASFTVSYHLGDFVDKSHQTLPFICHCHYDLLKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYW4</accession>
    <name>A0A3R7PYW4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TSP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_025379</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000969">
        <property type="protein sequence ID" value="ROT81457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYW4"/>
    <dbReference type="OrthoDB" id="6357296at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1080.10:FF:000001">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1080.10:FF:000002">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017897">
        <property type="entry name" value="Thrombospondin_3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008859">
        <property type="entry name" value="Thrombospondin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05735">
        <property type="entry name" value="TSP_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51234">
        <property type="entry name" value="TSP3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51236">
        <property type="entry name" value="TSP_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="TSP C-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="296"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="393"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="7">
        <location>
            <begin position="429"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="TSP C-terminal" evidence="9">
        <location>
            <begin position="465"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="263"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="364"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT81457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="702" mass="76817" checksum="22D6AFC15866405D" modified="2019-04-10" version="1">MKNLTYSFHPDTKQTELLWHDPFPWSRKLLYRVKILHRPLIGTIRVFLSIGPTLLADSGNIYNDVLRGGRFGPYCQLMPDIIWANIKYRCNDKVPQEMYDGLSGAQQALVEIEEWTMYPPCWDCHSHAFCTILDTSHTCTCNPGYAGDGTKCSNPCHSTVCPEGKFCNHILTAPFYTCDAYPAWSLLQPLCPKGEAGDGTTCGPDRDMDGRPDADLGCLDERCRLDNCIDIYNPDQFDHDGDDVGDACDYDLDGDGRSIEWDNCPSVMTNDQTDSDGDEHGDACDNCPSTPNLTQRDADGDGLGDECDPDMDNDGLANGGDNCPDVVNAGQADSDGDGVGDACDNCPSIANVGQADADQDFVGDACDTDTDTDSDSIQDNLDNCPSIANSDQKDTDSDGSGDACDTDADGDGILNTNDNCPLVPNGGQADSDGDGVGDDCEGDYDNDGVPDGTDICPKNAQVFTTEFKRVMIIPLEAPDDGPNCNWQFLAGRTGFFQRDEGDTSAAVGDVSLGSVDYEGTFTIESTDDDFVGFVFSFQDNRKFYMVNFKEAAQQLSTPAISDQGLHLKLVESSTGPDLDLQYGIYNSATSPGQVTLLWQDKSVRWKPNTFYHWKVLHRPNIGLIHFTMYENGKFLSTSGNIYNSRLKGGRLGPYSYSQRRILWVYLKYSCNEKVPQAIYDDLPPALQAQVEVEDGTYQPSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2S6</accession>
    <name>A0A3R7Q2S6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-2-oxoglutarate aldolase, mitochondrial</fullName>
            <ecNumber evidence="4">4.1.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Dihydrodipicolinate synthase-like</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Probable 2-keto-4-hydroxyglutarate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_014902</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the final step in the metabolic pathway of hydroxyproline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:30687"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:62213"/>
            <dbReference type="EC" id="4.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:35639"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:71685"/>
            <dbReference type="EC" id="4.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002863">
        <property type="protein sequence ID" value="ROT67033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2S6"/>
    <dbReference type="STRING" id="6689.A0A3R7Q2S6"/>
    <dbReference type="OrthoDB" id="191315at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008700">
        <property type="term" value="F:(R,S)-4-hydroxy-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00408">
        <property type="entry name" value="DHDPS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128:SF66">
        <property type="entry name" value="4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="DIHYDRODIPICOLINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT67033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="20462" checksum="E271B7495896B6B0" modified="2019-04-10" version="1">MTNVVNCSTTSSLPVPAQLVPIPQLERPVDEKSISKCQRRDEALHSHFTAVADYSPVPVILYSVPAFTVIDLSLDVIAALAQHPNIIGIKESGGDISKIGAIVHRTRSCDFQVLAGSASFFLPCLQIDLRACNSALSDPRLAPHGFWQAALFHRHPWAFLFSALMTPGFSAGLPRALWLRSFTASSGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4A3</accession>
    <name>A0A3R7Q4A3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histone acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="35" type="ORF">C7M84_007551</name>
    </gene>
    <organism evidence="35 36">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="35 36" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="35">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="35 36" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="35">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>(S)-lactoyl-CoA + L-lysyl-[protein] = N(6)-[(S)-lactoyl]-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61996"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:19466"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:231527"/>
            <dbReference type="ChEBI" id="CHEBI:231528"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="24">
            <dbReference type="Rhea" id="RHEA:61997"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="35">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01000196">
        <property type="protein sequence ID" value="ROT85748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A3R7Q4A3"/>
    <dbReference type="STRING" id="6689.A0A3R7Q4A3"/>
    <dbReference type="OrthoDB" id="899at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140297">
        <property type="term" value="F:DNA-binding transcription factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048511">
        <property type="term" value="P:rhythmic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05495">
        <property type="entry name" value="Bromo_cbp_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20910">
        <property type="entry name" value="NCBD_CREBBP-p300_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15557">
        <property type="entry name" value="PHD_CBP_p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15802">
        <property type="entry name" value="RING_CBP-p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02337">
        <property type="entry name" value="ZZ_CBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1020.10:FF:000002">
        <property type="entry name" value="E1A binding protein p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.90:FF:000003">
        <property type="entry name" value="E1A binding protein p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.10:FF:000001">
        <property type="entry name" value="Histone acetyltransferase p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1630.10">
        <property type="entry name" value="Nuclear receptor coactivator, CREB-bp-like, interlocking domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1020.10">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031162">
        <property type="entry name" value="CBP_P300_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008160">
        <property type="entry name" value="Collagen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013178">
        <property type="entry name" value="Histone_AcTrfase_Rtt109/CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003101">
        <property type="entry name" value="KIX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009110">
        <property type="entry name" value="Nuc_rcpt_coact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014744">
        <property type="entry name" value="Nuc_rcpt_coact_CREBbp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037073">
        <property type="entry name" value="Nuc_rcpt_coact_CREBbp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056484">
        <property type="entry name" value="PHD_P300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010303">
        <property type="entry name" value="RING_CBP-p300"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038547">
        <property type="entry name" value="RING_CBP-p300_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035898">
        <property type="entry name" value="TAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000197">
        <property type="entry name" value="Znf_TAZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808">
        <property type="entry name" value="CBP/P300-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13808:SF1">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01391">
        <property type="entry name" value="Collagen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09030">
        <property type="entry name" value="Creb_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08214">
        <property type="entry name" value="HAT_KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02172">
        <property type="entry name" value="KIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23570">
        <property type="entry name" value="PHD_P300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06001">
        <property type="entry name" value="RING_CBP-p300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02135">
        <property type="entry name" value="zf-TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01250">
        <property type="entry name" value="KAT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00551">
        <property type="entry name" value="ZnF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47040">
        <property type="entry name" value="Kix domain of CBP (creb binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69125">
        <property type="entry name" value="Nuclear receptor coactivator interlocking domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57933">
        <property type="entry name" value="TAZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51727">
        <property type="entry name" value="CBP_P300_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50952">
        <property type="entry name" value="KIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50134">
        <property type="entry name" value="ZF_TAZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="16" id="KW-0007">Acetylation</keyword>
    <keyword evidence="20" id="KW-0010">Activator</keyword>
    <keyword evidence="23" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="18" id="KW-0090">Biological rhythms</keyword>
    <keyword evidence="19 26" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="15" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 27" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="36" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="21" id="KW-0804">Transcription</keyword>
    <keyword evidence="17" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="13 27" id="KW-0862">Zinc</keyword>
    <keyword evidence="12 28" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TAZ-type" evidence="31">
        <location>
            <begin position="122"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="KIX" evidence="33">
        <location>
            <begin position="443"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="30">
        <location>
            <begin position="921"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="CBP/p300-type HAT" evidence="34">
        <location>
            <begin position="1141"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="32">
        <location>
            <begin position="1528"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="domain" description="TAZ-type" evidence="31">
        <location>
            <begin position="1589"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TAZ-type" evidence="27">
        <location>
            <begin position="122"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="TAZ-type" evidence="27">
        <location>
            <begin position="1589"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
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            <begin position="65"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="213"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="527"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="800"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="1373"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="1704"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="1809"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="29">
        <location>
            <begin position="1915"/>
            <end position="2040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="29">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="29">
        <location>
            <begin position="101"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="29">
        <location>
            <begin position="246"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="29">
        <location>
            <begin position="541"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="29">
        <location>
            <begin position="613"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="29">
        <location>
            <begin position="648"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="29">
        <location>
            <begin position="800"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="29">
        <location>
            <begin position="834"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="29">
        <location>
            <begin position="850"/>
            <end position="864"/>
        </location>
    </feature>
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            <begin position="878"/>
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    </feature>
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            <end position="1385"/>
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        <location>
            <begin position="1386"/>
            <end position="1398"/>
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    </feature>
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            <begin position="1412"/>
            <end position="1433"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000313" key="35">
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            <dbReference type="EMBL" id="ROT85748.1"/>
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    <evidence type="ECO:0000313" key="36">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
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    </evidence>
    <sequence length="2040" mass="221624" checksum="C425C8B2134B4468" modified="2019-04-10" version="1">MLTLSLSLQNPSMGQPAISGNYGFGGQGVQPGMDGNVGQANSGMGPGQRPMGMTLPPRYPNQDMMSIMNSMPRGPQPGPGPAGPGAQGVPSGPPVGPPGPINSGPAGPGQMMPGQPRANPADPEKRKLIQQQLVLLLHAHKCQRRESQANGEVRQCNLPHCKTMKNVLTHMTTCQAGKSCPVPHCASSRQIISHWKNCSRQDCPVCEPLKQADKKQQPGAGGVPGQIPPTVSQPGPSPGGVQGPLTGPPGPPGPPNVPGQMTAGPPGQNAGPRPGGGSGVKRVYEGDNLPPNLSGPPGPTDPIMRTLRPQVPTAGVPGMAANNQQGGPGGVQGGPTGVPNAPGMPGQMVRPGVPNKGPDGTMMGTPTSQGMNSPSMIGRGPNAATGPMNTHQPQQIISKPPNVGINQNSPVVSTISIPEWLNIPNQPAQLPSGFGSVTAKPVKGTKEWHQSISNELRNHLVHKLVQAIFPTPDPQAMLDKRMQNLVAYARKVEGDMFEMANSRPEYYHLLAEKIYKIQKELEEKRLQRKQTTPGVTGPQGPQGPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGSLVAPSPILTPTTSGASSIAGMAGRPTGPRPVHPQGSLLSTNPLATNQVSQPTSICQPSSNAQMGMGPLPITTSASTTTTNSSMAGQFPGGPVPHNDMLQGPRPSVPPPPYSTPNDTPIMNQMANRTSPAIPVSSVAATLGIPISMASQSTPSSMGSLSSNENSFPPTSQPGIITTNANSENTVMPTSIHTKDSSVGSQPVAVEMTEEKPEKPCKVVKMEPIEIKTEIKTEPEETEGKEIKTEPKSEPMEVSTASEEASVKQEMVVKEEPKSPAASTPSESGKSNETGSKGDKPTSSAVVPIPRPAPTPPKPTPVPSTPAKERPPLFKPDELRQHLVPTLEKLYRQDPESIPFRQPVDPSALGIPDYFDIIKKPMDLSTIKRKLDTGQYTDPWDYVDDVWLMFDNAWIYNRKTSRVYRYCTKLAEVFEQEIDPVMQSLGYCCGRKYTFNPQVLCCYGKQLCTIPRDAKYYSYQNRYTYCYKCFNDLQGDTITLGDDPSQPALTIKKSQFQEMKNDALDLEPLVECLECGRKQHQICVAYLETIWPQGFVCDLCHKKKNTKRKENKFTAKKLPTTKLSNFLETRVNNFLKKKEAGAGDVYIRVVSSTDKVVEVKGGMKTRFVDTGQLSPEFPYRAKALFAYEVIDGMDVCFFGMHVQEYGSDSPTPNTRRVYLAYLDSVHFFKPRQYRTAVYHEILLGYLDYVKQLGYTMAHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKGIIERIVLDYKDIHKQAFEDNLKSPAELPYFEGDFWPNVMEESIKELDQEEEEKRKQEEAAAAEAAAQAAMGVEEEEETSQDGKKKGQKKHKNKNKSKSQQKNKSKSKNNAAGCNDLAQKIFVTMEKHKDVFFVIRLHSAQSAVSLPPIQDPDPIMVCDLMDGRDAFLTLASERHLEFSSLRRAKYSTMIMMYELHNQGQDRFVYTCNHCKTHVETRYHCQECDDFDLCTSCFKSEGHPHKMIKLGLDLEDGVSTESKNLNPQEARKQSIQRCIQSLVHASQCRDANCRLPSCQKMKRVLSHTKSCKKKNNGGCAICKQLIALCCYHARNCKEQRCVVPYCSNIKQKLRQQEMQQRFQQQQLMKRRMQQMNARMISCGNPQQAASTPQPVQSPIHTSQPSVKPSAQGPSPNVMKAIAQVQEEAARQTGPATAVSYGKGNPGNGAVSQAPMMPPPITPQQQVRPAIPVNTMAPITRMEMMWNRYPNPGGMPGQPQQGQAGGIRPGMMAQPNQVAQHSGAPGPPPVMGPPGQPGQPGQPGQPGTQPQRNATQALQQLLQTLKNPSSQHQQSEVLHILKTHPQLMAAFIRHRQIQQQSQQPPQPNPQQPPQQPPQGPGGQPGMIAPCGSMPGTVQGSMQPTGMQPTGMQPTGMQPNIQPGNMQGGIVNQMGTNPPMQGQQQPMGVPPTQSNMSHQQQCNQGASSSHRRPWGIPRDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-09-13" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q575</accession>
    <name>A0A3R7Q575_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012959</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002624">
        <property type="protein sequence ID" value="ROT68897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q575"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="462" mass="51387" checksum="7D74CFD8DB444AB2" modified="2019-04-10" version="1">MSQQRTPSTPAALVTRLREFMPYLVSRDSIPHFKGETSACEPLKRNQEVESYIRAIENLVRPTSNDAYIRAARASCRGRAETIINSESFDGIQDWDTFKRQLRRKFRGTYTASDFFKVLYDHAMTERQAPMDFFLEVEASVFQGYRDHRGAVGEPSELIRRVFLAGLPSTLRDLLVLKDDCSPSSLPRPPRSFGTPSPNNIQEDDYQLRRRTPDRPPRTRDRYDLFPVATSPHLLSLFPRLQHHGVMYGVNIIEVQPTAPGNAELLRVSLHHQPTLVSVVEGAVTCLVSAPFREARKEGFPTSLATLQEGTRTRSITVQTEPVQTTAAVTTPAVGGRPVVALSVDGKTLLCFIDTGSQVTLVKPSALEVLDPAKKLRHHASSKILQGVSGEPFHPAAEVTLSFNISKDLVLLHRTIVADLSFHGDVLLGTDFLRRQDFTLQSEAQSPHGLLILGGCELPPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QDJ8</accession>
    <name>A0A3R7QDJ8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polypeptide N-acetylgalactosaminyltransferase</fullName>
            <ecNumber evidence="10">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Protein-UDP acetylgalactosaminyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_017931</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01003315">
        <property type="protein sequence ID" value="ROT64145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QDJ8"/>
    <dbReference type="OrthoDB" id="6119243at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23459">
        <property type="entry name" value="beta-trefoil_Ricin_Pgant1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02510">
        <property type="entry name" value="pp-GalNAc-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000195">
        <property type="entry name" value="Polypeptide N-acetylgalactosaminyltransferase like 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045885">
        <property type="entry name" value="GalNAc-T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF43">
        <property type="entry name" value="POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 10" id="KW-0430">Lectin</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="11">
        <location>
            <begin position="303"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT64145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="439" mass="51007" checksum="03DF46ACB1A17707" modified="2019-04-10" version="1">MRFPRSRLLLQVGHQVVRCKEIHYDADLPSASVIIIFTNEAWTPLIRTIWSVLTRSPSRFLKEIVLVDDFSDRDVLIFLDSHCEANEKWMEPLLQRIKESRSAVVVPIIDVIDDKTLEYYNGNGRYFQVGGFTWSGHFTWIEISDAEQKRRGSPVGATRSPTMAGGLFAIERNYFWEVGSYDNGMDVWGGENLEMSFRVWMCGGTLETIPCSRVGHIFRSFHPYTFPGNKDTHGLNTARLAETWMDEYKRLFYLYRPELQNADWGDISERKDLRNRLQCKSFKWYLTNIYPEKYILDEDVIAFGRLRNNATKPDICLDNLQRNEKSAYDMGLYNCHTFVASSQFVSMSKNGELRREDVCAEVPVFSAQAVEKVRMVRCHGQRGNQEWLLAKTGHIIHKATNKCLDRGDKQAMDDVFVTTCANTRTQQWWFDHYLPVSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFS2</accession>
    <name>A0A3R7QFS2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NACHT and WD repeat domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003909</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001524">
        <property type="protein sequence ID" value="ROT77433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFS2"/>
    <dbReference type="STRING" id="6689.A0A3R7QFS2"/>
    <dbReference type="OrthoDB" id="6134417at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052752">
        <property type="entry name" value="NACHT-WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057588">
        <property type="entry name" value="NWD1/2-like_WH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871">
        <property type="entry name" value="BETA TRANSDUCIN-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19871:SF14">
        <property type="entry name" value="DUF4062 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25469">
        <property type="entry name" value="WHD_NWD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NWD1/2-like winged helix-turn-helix" evidence="3">
        <location>
            <begin position="17"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="221" mass="24944" checksum="CDB2E996E89E9793" modified="2019-04-10" version="1">MACQWTGAETQLPLQPNLMGLINAVFDELEAAYGQVEVSHTLGYLTAAKHGLSDSEMIDILSCDEAVLEKIFVHCTPPEQVGQRCQEAGPVYEAGVEEGKDRYVLDQPTKYRGSNMSKISVQSLFSRHNRRKLDELPYQVLQLRGRILEEFVLKFDWVYEKLCGSDTYQVLEDVSLALRNHSNNIELVLLKEVLEARRLRPRIRRKAVLLAGKGARKGAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFX4</accession>
    <name>A0A3R7QFX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001509">
        <property type="protein sequence ID" value="ROT77576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFX4"/>
    <dbReference type="OrthoDB" id="6380903at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018753454" evidence="2">
        <location>
            <begin position="20"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="182" mass="19940" checksum="BC891CDCF94FAFE9" modified="2019-04-10" version="1">MLPLKPVIAVLAFVTVATAAKLETLDNASLRAIDSEEVAPGYQPNQVPVQGDWQEEEKDDDDDLYDYDYEDYPEEDHSEEYPSHQDDDSDAGEYEDYGEEEFVEQGQGVSDGVLRRQKRKLIYGGGAYGRRGGSRGGSPYGRRRSNQNYHGPDYGPGGGGPSGGYYGRRSSPVAAPPAGRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHJ7</accession>
    <name>A0A3R7QHJ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="3 8">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_002158</name>
        <name evidence="9" type="ORF">C7M84_008791</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>S-formylglutathione + H2O = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the esterase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="3 8"/>
    <dbReference type="EMBL" id="QCYY01002111">
        <property type="protein sequence ID" value="ROT72798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001287">
        <property type="protein sequence ID" value="ROT79140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHJ7"/>
    <dbReference type="STRING" id="6689.A0A3R7QHJ7"/>
    <dbReference type="OrthoDB" id="420518at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000002">
        <property type="entry name" value="S-formylglutathione hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061:SF0">
        <property type="entry name" value="S-FORMYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT72798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT79140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="254" mass="27868" checksum="52C1CDBD922B0D85" modified="2019-04-10" version="1">MKFAVYIPPQAESGPVPVIYWLSGLTCTEQNFITKAGAQQYASKHGFLVVAPDTSPRDCKIPGEDDSWDFGTGAGFYVDATEEKWKTNYRMFSYVTKELPALVAANFKVESDKAGIMGHSMGGHGALICALKNPGQYKSVSAFAPICNPVNCPWGVKAFSGYLGEGNKDAWKEYDACELAKKYNGPPLEIMVDQGKADNFLTQGQLLPDNLVGACAEGGVPIIMRMQEGYDHSYYFMATFMADHFDHHAKFLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QIK5</accession>
    <name>A0A3R7QIK5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BPTI/Kunitz inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_001205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001161">
        <property type="protein sequence ID" value="ROT80045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QIK5"/>
    <dbReference type="STRING" id="6689.A0A3R7QIK5"/>
    <dbReference type="OrthoDB" id="4473401at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00109">
        <property type="entry name" value="Kunitz-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.410.10:FF:000020">
        <property type="entry name" value="Collagen, type VI, alpha 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.10">
        <property type="entry name" value="Pancreatic trypsin inhibitor Kunitz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002223">
        <property type="entry name" value="Kunitz_BPTI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036880">
        <property type="entry name" value="Kunitz_BPTI_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020901">
        <property type="entry name" value="Prtase_inh_Kunz-CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050098">
        <property type="entry name" value="TFPI/VKTCI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083">
        <property type="entry name" value="KUNITZ-TYPE PROTEASE INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10083:SF328">
        <property type="entry name" value="TISSUE FACTOR PATHWAY INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00014">
        <property type="entry name" value="Kunitz_BPTI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00759">
        <property type="entry name" value="BASICPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00131">
        <property type="entry name" value="KU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57362">
        <property type="entry name" value="BPTI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00280">
        <property type="entry name" value="BPTI_KUNITZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50279">
        <property type="entry name" value="BPTI_KUNITZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="BPTI/Kunitz inhibitor" evidence="5">
        <location>
            <begin position="45"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT80045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="213" mass="22490" checksum="E1FFBDE90D995529" modified="2019-04-10" version="1" fragment="single">MKAKKNDKNGGEGRMEEHGETPRPEKFSLPPHVAGTNGMVGVSRCQQPPETGPCRASFLMWAYNASSGTCVTFTYGGCLGNENNFKTEHQCSAACPDEVPCPEDASKVCRVSETSCRNASCPGDELAACRVTPCTCDVSFVSEDGEEVDCHKAVDAADGPEGRGSDIDLADGSGGMKPTEASRAGDSGDGGAREKDNLERDKAKNKAMVDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QKG0</accession>
    <name>A0A3R7QKG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002445">
        <property type="protein sequence ID" value="ROT70292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QKG0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="472" mass="51643" checksum="5242AD52586A04BB" modified="2019-04-10" version="1">MSAHILKAPRAHPPHPPRHSPPDCRTIHLPPAALHPQPPIHLPPPPLPHCRPSPPPPTAIHLPPRIHTPLPPIHPPPRRHPHPPPPPNQPHPPHRPPIPIQPTPPPRRRRGRPGDSRSGSFSGLLFFLSLSVCLSVCLVRNPPLSLSLSLFLSLLLFSLTYHLSICFLFYSLSSLSMYLFIQLYLFYPILSLSLSPKWSVYLLQSLFLSVYMVYAGWAWPLLGIPLSLLLHTLSLSFPSFFPNSLFHLPLSPFPSPTPPISHTAHTTAPAAPQSASLPLFLASRFPSSSSLPHFLALSLVIASPSLVTLPFLPHQSPSLPFSCALFAISISHTPTHNSHADPHNPPHSHGFSSIPSILSCPSPDPYILLPLSSPLPPTPPSQNPQIGGLSPSISPPFSPFLSRLPLIPPPLFRFPLPPPSPNPQIGPPSLAFLSPLFTFSLNLHFSLPFLLISFTHLTTTPSPNRLFSPRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QMI6</accession>
    <name>A0A3R7QMI6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CUB-serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009366</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002187">
        <property type="protein sequence ID" value="ROT72248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QMI6"/>
    <dbReference type="STRING" id="6689.A0A3R7QMI6"/>
    <dbReference type="OrthoDB" id="6380950at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="150" mass="16434" checksum="3FD3CBF197FD8C5C" modified="2019-04-10" version="1">MTTSDYVLVGDHNLYSGSEANSQWMQIAEIVNHPSYDSNTLDNDIALIRLKTEIQFPSDNKIAPVCLPTAGEMYDSVDATITGWELNRRGDSGGPMVVEENGKWKLVGVVSWGYGCARPEGPGVYARVTRRDMETQGYIATPAEGFSQSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNH0</accession>
    <name>A0A3R7QNH0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-3-methyladenine glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.21</ecNumber>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">3-alkyladenine DNA glycosylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">3-methyladenine DNA glycosidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">ADPG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-methylpurine-DNA glycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C7M84_022077</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="22 23" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.</text>
            <dbReference type="EC" id="3.2.2.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">Binds MBD1. Binds SSBP1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.21" evidence="4"/>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01000505">
        <property type="protein sequence ID" value="ROT84732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNH0"/>
    <dbReference type="STRING" id="6689.A0A3R7QNH0"/>
    <dbReference type="OrthoDB" id="434041at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00540">
        <property type="entry name" value="AAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.300.10:FF:000001">
        <property type="entry name" value="Putative 3-methyladenine DNA glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="entry name" value="Methylpurine-DNA glycosylase (MPG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00567">
        <property type="entry name" value="3mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429:SF0">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="21">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="27"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="54"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="18">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00068926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00076879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00078171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00082988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ROT84732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="511" mass="55625" checksum="9EDF0A69D60D0309" modified="2019-04-10" version="1">MYLSDHVLEGLKKSGFIRPSPIQLAAIPLGRCGLDLVVQAKSGTGKTCVFTVVALEMLSVTASTTQVLVIAPTREIAVQITQVINSIGIGTPGLRAYAFIGGIALSQDKAKLSCCHIAVGTPGRLAQLVELGLLKLDNVRLLVLDEADQLLTDLSARGLDSEHVNLVINLDMPRDQATYLHRVGRAGRFGSRGGAITLATEGDDWTAMRAIVTLANVKAYLLQEGWDSNITSKEVEGMEEVEMLGEEELNLWLESQVAASSVLPARRLTYSFYNQECVTLAKALLGQVMVRMIDGVRVSGVIVETESYLGGEDVASHSHNNKRTPRNEPMYMKPGTAYVYPIYGMYFCFNVSSQGDGSCVLVRALEPVEGMSIMAVGRNQRRKNTTPLKTHQLCNGPSKLCQALDMTKDSCNKLDLSTSNVLWLEAGTSIPESQVVIGKRIGIESADCSLAPWIHVVELDSKTFLISLRRHTVNMKASGTLKEYSVIGRKLPSELVPIPSCTRCESLLRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QNK9</accession>
    <name>A0A3R7QNK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transient-receptor-hypothetical-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_021942</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000485">
        <property type="protein sequence ID" value="ROT84855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QNK9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070679">
        <property type="term" value="F:inositol 1,4,5 trisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015279">
        <property type="term" value="F:store-operated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051480">
        <property type="term" value="P:regulation of cytosolic calcium ion concentration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007338">
        <property type="term" value="P:single fertilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002153">
        <property type="entry name" value="TRPC_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10117">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10117:SF80">
        <property type="entry name" value="TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="278" mass="31045" checksum="2D98FB574FC80677" modified="2019-04-10" version="1">MTPYSPILIHNVEQNRFPSFSHDSQNTQRSSEYKHAEAVICTGSNASRTGSDALCSGSRNQTGSDPPSRPALEEDRKPRWLAYSLIILMATPWTRRSGCSWRRPKRGDKHTMMRCLSPPSPVNVNCTDILGRSAIQIAVDNENVEIVELLLLQETVKIGDALLYAITEGVYKIVEMLINHPSITPEMLANDWVRVRAGGEESSDFDPNISPIILAAHCNQFEILQLFLAHSDLGPSRPGRGPPPPSPSPPPHASIFQLHVLTQPFTEERDYDLYDRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QV32</accession>
    <name>A0A3R7QV32_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001263">
        <property type="protein sequence ID" value="ROT79289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QV32"/>
    <dbReference type="OrthoDB" id="6377406at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312">
        <property type="entry name" value="NACHT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46312:SF2">
        <property type="entry name" value="NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="299"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="891"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="971"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1027" mass="117022" checksum="FFAE627E029E5B5B" modified="2019-04-10" version="1">MALTRLSTGIQQEDHNTFRLYKAHRGPARCVMLTILNWGCQKAPEVTYEDYLLQNLGFSSKKYKTIFDGAQREKLKCHSRGDEFDISLLYKLIQNTCAGVAPASDSVWTSEDFSRLEFLVNYIKNSRNNLAHNDHEISNSEIVRRLEKLRDVLVTTLKAGRDLYCVQQSEVDALIKQVSDAITAIREHPFAQTDVLQYQNDLLFEDLREIMSTDGAKEVAKIFSRNNLLNLNPVSFISGGDCHLKVDRVFIDIQIYSVESGERKAIDYRDILVYSHETNNYPDDHSINSSQQSIQAKRVIHLVEGDPGSGKTTLLKFIMSDWKKQTNIIKELSDYHLVLYFECLNPYKDSLADFLVSQMPLTSTRFHKSDLVRCLLGLKVLLLIDGLDELNSASKRFFKEIIHVKRNSDISVICTTRSEKLKEISGMISSDLTINYFKLLGIPSNKRGKFVQQYHEELKRRGMSAGNTDSIVQYVENAPQQLNDFFVYPLNLVLFTYLWATRPESVNAVTSVTVLYAEVHSLIVEKLHRRLLDDPDIDYIPSEEIKGRCEQFLDVLYQFSFATLSCNMLYLDQEHVNRLLEVCSETGLAAKHMMSSFLVVELTSSGEQYVERHRFPHKGIQEFYGAQHILSIISNENLAKNRAQVLEALEKCLSKFHISSYEKQEIASWASELSERKRISTLLGKTCPVRFQEKGKYTNLLQHLVGLLRYQTSYLLLHYVEEIVGLLNDSGDLFFDQWADLLKKTDYDALVAKEVARFVCQISWIVRDDQERAAATLIAHRCPRVLSIELFKEPKDLPHLADLLGSAFAQGCEIRLHLHSHWREPKSGSSDGILRALQRSSLNETQEWEYYLEHTWKKSLTQFTGRATSPAVLASLVGTIEELRVAVRTDDEALDWSRTQKSQTPIPEKMATPQTEPPTEQEGNASRTNKETEQGLLLSQKSPEPVLPGSKPTLDEPTTAMEATSKTGKISPKRKLPLGPRASRRVRQMGLELIVTEVPLTRTQLSVLSKGRSFVPGPPPKKPCWRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYD0</accession>
    <name>A0A3R7QYD0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000721">
        <property type="protein sequence ID" value="ROT83198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYD0"/>
    <dbReference type="OrthoDB" id="6381815at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="41166" checksum="446982FF609EEE3F" modified="2019-04-10" version="1">MLGDSGSESEEEEVAQESDIKSLCEEKEGVTGRNADVTSKEENNDVSECKTEEVEETGDEYKPNISTAVTEEEETKQVDVVDHGNSQMALTPEPEEPVKTEEPEESKPDIAEERLTPPLHYFNPNSAKDEQKEVDDEPDMIEEACSDNIQTEVTSETLEESREALDPVEESRMEIDQPYEMSEDQNDSENDCKSAEVEDYYHDDASVEGSSHIADRVDEKVTQKVEPKIVQRIGIEKEEKESLEGEGSDVEDHPSGIHSSQTRLESGSESIAEPMRVSDVTTSSGSGTTYMLVAVDAHGNTVPTVPTPALSEGGSNLVAVEATMEDGTTRTLYIDPSQLGPNVDLNNLMLHIDTSGQEHVIIPSSFIRILKRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SLF0</accession>
    <name>A0A3R7SLF0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_016255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01003040">
        <property type="protein sequence ID" value="ROT65767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SLF0"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="4">
        <location>
            <begin position="359"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="544"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT65767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="569" mass="63413" checksum="EA3EBC85F59E9124" modified="2019-04-10" version="1">MPTTRVHIRVKLRIAPLKTEESTVTLPLRDPRHPRAMTTLTTPRSFMDSDLLCNVSASTADGTALVLTDHVRVKGCAALPSLYKIVNGKCQVHLMNLTPVPLEIRGGVPVLNFEFTDLPIREFDLPTPSPVCAASHSPPQVNNEVLQDILSQKLAFQDGYNILEKIFHDYPTVLPSKDRLIGSTDLIEHSISLEPDAKPVYIPSYKIPHSKRKALENEVQGMLDMNLIKRSNSPWASPMILVPKKDGSFRLVVDYLSEHEKKLRQVFERLASAGLTINPGKCQFFRSKLDFLGHTLTSNGIAPNQNKVQAVIDFPRPQNQKDLKSFLGLSGFYRPFIKDYGSIAQPLTTLLKKDVPFEWAKETEDSFLQLKALLANAPVLAFPDFELPFVLTTDASSVGLGATLHQKVNGKLRPIAFASRTLKPAERSYHTTDRELLAITYALRHFRELILGYKIEVHTDHSALTTALHGRDPHGRRARAIEVLAEYDVTIVYLPGRQNVVADALSRAPLPSPAELQACKSTPFPPSFAKRHEARTTAPVLANVANQPVDPPPRKKFAVRNARTPFTWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMF7</accession>
    <name>A0A3R7SMF7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative receptor-type tyrosine-protein phosphatase delta-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014788</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002843">
        <property type="protein sequence ID" value="ROT67144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMF7"/>
    <dbReference type="STRING" id="6689.A0A3R7SMF7"/>
    <dbReference type="OrthoDB" id="6362880at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF527">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="635"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="435"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="916"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1137"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1169" mass="128491" checksum="5626DC8759384F4B" modified="2019-04-10" version="1">MKPISCPGGRSFLGKNTTDNSTKISVCPYCKIILEVQAGNEEGISDMETTDFETEAARPTSRVRATHCSPTACSASLTDGCDTYNGPDMAIEYTFLPEGSERQRCHEKTFNGSQTSRRVPLGEVLDLDSLKENLLPYTTYRFEGLMPGRQYNLTVNVCNRRMCSDSVWTLNWTVPESPSVHGTLTWISNQPSSTTVYLPYILRKSSVDVHNKQYVMVREDEGDTAKWGDAEYLISLAKGWDKQRDISDVEWISADDEVARAPDVRFIIGDNTTRHGVHNHPIESDKCYLVAVVSVATAGPHERYHVSDAKPLCNGPRPILVAVGIIFGIVLLLALTAVALQLRYGKQISQKNISVAAVENSNGPIGNAEPSRGFEIPAQTKPLLVRQESTEFMSSLEPKEEYTHRESHIYENLGRKISQEHLEAYLARAINSQDIDFEFKSVPVSMPKSCSYGERMENKRKNRYRNNLPYDDTRIELPMLPDQPFSDYINASLIQGHVEGTDYIATQGPKDYRNDTVSDFWRMVWHCRSNIIIMVANLVENGQDVSYVSERSKKGMCSLITSTSLSPPPPTLPHMPSSLPPPLLTCPLSAPFPPSRSVSYPQPLLSLSIPVCPVLSLFSSAFPRSHSSLSLGSRPLSHLCVSLISLLLLLYSFSFPLSLISPSLLPALSPPPSALSSSFPPAIRLLSSAPSASPIPSLPRFPAALFSPPLLPALSYASHPSSFPRSSASSSAPSPHLGLGLRPPLPPSRSSLLIPSLLPALPPSLPLLFRSPLASSCLPASLLPSYSALSASPLPALLPALPPSSPPSFPLSLPPSRSPLLLYINLSTYLSFCNHAPSSHHGVPHNPFGLALMVSAIREQEAEGPTSRPLQIQYNFGHRILQEFLFGINTSFACGDFPKELSRLRETDTEDGASVLEMQYKKLKNLPKVLSFIMAKNPACASLNRNPDILPADNRMVFVQSLGGGLENQYVNAVRLNSLDRKDAYIAAEYPQQHTMQSIWALVYERRIPVWVLMQTFPENDQEYPSVIPALERQQVGQFLLTLTGLQSYQNFVEYYIEIAVQGSRMASPHMCVLGRNERLAARPGPPILSGASLAVAGNDAVIHFTRPPLPYAVLLPHTCRIPLQLFDQMDKGGCSAKADARQPRCGRLGAAPSKKVEKGPRKDAGEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMW3</accession>
    <name>A0A3R7SMW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative splicing factor 3A subunit 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002757">
        <property type="protein sequence ID" value="ROT67812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMW3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018651728" evidence="1">
        <location>
            <begin position="18"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="560" mass="60679" checksum="11E188818524FDD0" modified="2019-04-10" version="1">MLSFVPLLPTLFTTLFTLPLHRSRHSAKIPTALPLELPSLHPLELPPLHPLELPSLHPLELPSLHPLIPSSFRHCIPRASHCIPRASVIASPRASVIASPRASVIASPRASVIASPRASAIASPRASLIASPRASAIASPRAFPSLHPLELPSLHPLELPSLHPLELPVIGIPRRAFIPLELPSLHPSSFRHCIPSSFRHCISSSFRHCIPSSFVIASPSSFRHCIPSSSVIASPRASVFASPRASVIASPRASAIASPRASSLHPLELHPSSFRHCIPSSFRHCIPSSFAVLHPSSFVIARASIVSLSCIPSSFRHCIPSSFRLCIPSSFPRLHPLELRHCEASVIALELIRSFAFIEHRHCSIELPSLHPLELRALHPLVALHPLELTSLQSPRASVIASPRSCPSLHPLELPSLHSPRSFRLHSPSFRIGISPRASVTLHPLEHPSLPSPSRASVFCIPLELRHCIRLELSVHCIPRASVIAIPSSCRLCIPRASVSCIPSELPSLLSALSSFRHCIPSAPSCNPLGFRLCIPSSFRHASPSSFRHCIPSTSRIASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SPV0</accession>
    <name>A0A3R7SPV0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative heme-binding protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011628</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002468">
        <property type="protein sequence ID" value="ROT70100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SPV0"/>
    <dbReference type="OrthoDB" id="6424451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.80.10:FF:000002">
        <property type="entry name" value="Heme-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF1">
        <property type="entry name" value="HEME-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018622423" evidence="2">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22337" checksum="15B65753DABC6B33" modified="2019-04-10" version="1">MRTFAALALFAQVCQLALAIESAPYDLVNSAETYEERVYPAQKWVTTSHLSISHHEATSDVMFSKLFNYIDGQNDAAMKIDMTAPVTTLVIPGEGPNCENNFTMSFYVPAAHQDNPPTPTNPDVYIEERPELHVFSRRFHGFANDEDWIVNAAQLHDDLVAAGEEGVDFQTYYTVGYDSPFVIIGRNNEVWFMKNDMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVE3</accession>
    <name>A0A3R7SVE3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001586">
        <property type="protein sequence ID" value="ROT76957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVE3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="438" mass="49245" checksum="E0702856FB530B12" modified="2019-04-10" version="1">MLHITTTYFAADTKSQQPQHQLTPNLHPTIHHIPHHTSQSLHSHHNTHSHRTTRTPIPPSPTATQTTRQQYTTKPPAPKHRRHQHTLVLTQSPNHLPTLTIPSTLTPTRLFGLVCVLTLNQTLHNPPTTLHTTKHYTPYPTTKHHTTQSIYTTTTSTRTQPHIPPSQTQPPDHAKHHTYTSYTPSPKPIPPLYYLTSHITPIHSPSPPHHQQPGQIATIPLSTHNYNILPQNLLTLAASPTHTCTRTTTHTSLSPTQTPTHTTHTHHHTTTHTTTPNTPHTTHPTPHNLPPQHTTTPTTTTPHPYTPTHTNTNNTPNHHLAPHHQFPTPHLTHLPPHLPTVTTVKRATNKTTTTNHSHLDHNHTNIPTPLIQPPATELSFQTQRLPHHPSHTSYHHTSQSHNTTTHIPHTPYHYHPPSHHHPTTPSLHSTSHHTSQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SWM5</accession>
    <name>A0A3R7SWM5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_002456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001327">
        <property type="protein sequence ID" value="ROT78829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SWM5"/>
    <dbReference type="STRING" id="6689.A0A3R7SWM5"/>
    <dbReference type="OrthoDB" id="6358856at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018654919" description="C-type lectin domain-containing protein" evidence="2">
        <location>
            <begin position="17"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT78829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="725" mass="77079" checksum="5AE97D1974BDD9C7" modified="2019-04-10" version="1">MAALAFLLVFVASSAAGEVTLVHEGLGAGSSWGYSLLPSTFPLSWDEARSACEVVPGSMLARVGEGEAEAALGEYLKGVGMTGPVWLANRQTLPEVLEEEQRDMKGAPGDLLEEGVRTGDLSVGGDVGVTLRCTIYTVGVGMVHELCSARTVSAALCVQRCGVAAPQDVEETSVTVSGLQVCHHHHHHLGYSHCHPESGWAQVVCPPEPASPHHRKGPKRFHRGHRSRKGQSHKVFAASDDEGREAQGERPRIAKKIDLGFYKPDEARRIRRQADTKPEDVESILLKFRGGKKITNNDGTNKDNKDMKVEQLVDEPEVQKPVELEGEQQQNVIEESDTKSEDQQVTPKSPLPTEVSDEEKGPIIVVASGPIFVHDALPTPAQKEEQVPPTGKGTVVEVDITQTESVLIEASLADESAEEHMDESFSGVEVAGEAEEQSAPAQTSGGQDDAAETANRPIIFPEDPQPPNPDPTRSLINERGMDEGYPISSGQDAPSGDPGSEGTLPPASSIIFPGDDTPASDTNGAESFAREEEGPDEPPVTTVQTVALVPVIRDAMPEGEEDLTDMEVNPEINEIQDTDDAPEAGEMADKPKMDTTGMSEKPADEEPAEEARTDDVAEKPATADATENSSAEDTVEEPAAEDAAEKPTGDETVESTIGNTDSRSEEGAEGPAINLGSESSTEKETPVTGAKPETLSDPAPAQHSDADGQAGRQPLISQIFKGLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCJ5</accession>
    <name>A0A423SCJ5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-B22</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase B22 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_020299</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Mammalian complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003951">
        <property type="protein sequence ID" value="ROT61885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCJ5"/>
    <dbReference type="STRING" id="6689.A0A423SCJ5"/>
    <dbReference type="OrthoDB" id="13598at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20263">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045292">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033034">
        <property type="entry name" value="NDUFB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="16">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT61885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="142" mass="17402" checksum="C3B2741DD3EB48ED" modified="2019-05-08" version="1">MSFLQTEVICHSRKVCSLYKRALRNLESWYDRRPMYRYRAVLLRARFDENKDVKDLRVAQQLLDDGEKELFSLIQYQPKKFPLSPGGVAYEREVRAPDWVLDYWHPWEKAFYPDYFAKREQRKKEYVEWWEKTYGKPAEQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SDE1</accession>
    <name>A0A423SDE1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Myosin heavy chain type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_019932</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003753">
        <property type="protein sequence ID" value="ROT62231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SDE1"/>
    <dbReference type="STRING" id="6689.A0A423SDE1"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000008">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000009">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF7">
        <property type="entry name" value="MYOSIN TAIL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="11" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="9" id="KW-0518">Myosin</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="15">
        <location>
            <begin position="12"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="24"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT62231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="59398" checksum="C223BB6EBDE63C84" modified="2019-05-08" version="1">MQIESLNVRNLHLEKTKMRAAAELDDLHASAERAQALASAAEKKQKNFDKIISEWKLKVDDLAAEVDASQKECRNYSTEHFRLKAANDENIEQLDSIRRENKNLSDEIRDLMDQLGEGGRAYHEVQKNARRLELEKEELQAALEEAEAALEQEENKVLRTQLELSQIRQEIDRRLQEKEEEFDNTRKCHQRALDSMQASLEVEAKGKAEALRIKKKLESDINELEIALDHANKANADLHKHLRKVHDEIKDAEARVKEEQRHASEYREQYGIAERRFNALHGELEESRTLLEQSDRGRRHAETELNDAREQINNFTNQNTALTASKRKLEGEMATLQADLEEMLSEARNSEEKAKKAMLDAARLADELRSEQEHASSQEKMRKALEGTVKDLQTRLEESEAAAMKAGKKAVSNMEARIRELESALDEETRRHADAQKNLRKCERRIKELAFQTDEDKKNHDRMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKTQQELEESEGVTVVHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQX9</accession>
    <name>A0A423SQX9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002916">
        <property type="protein sequence ID" value="ROT66620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQX9"/>
    <dbReference type="OrthoDB" id="5969272at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="42194" checksum="DB5F2A2C952DC849" modified="2019-05-08" version="1">MSGEQYRMVLLGQRRPSAPQGLLYTSLLPSSGPTKLSYNMDTNDDDSLSRYCSRATNIVWSDLDGAPLTTHRKASRALPTDLDEVETESSHKPRRASRAHTTNLADLDPVPFAYRRATREEKKEYGESYAVMPYEPIVIEETLDTKPICRSDTVANLLDKYSNFSTKREFGYRGPTSAWARHLGETHAFVSTIPDTDDSMDDSRRTHSRTGPPVSAENDLAGLSRSREHSRSRTPRALSTGREVSAISSRDEPLRSSEIARSHDNPYSSRDNQISYGRDSQISYGRDSQTSYGRDSSMSHNRSRFSDIYEEDEDEVLPPLEERIQRRTAALELKDDFDMGLNLPKGRPGGALERYRQGRAREAQVFVTLKKQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSV9</accession>
    <name>A0A423SSV9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002824">
        <property type="protein sequence ID" value="ROT67287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSV9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="877" mass="95371" checksum="9829E0B8FA2A0714" modified="2019-05-08" version="1">MESDELRAGTPSRVALVAREMLSRCKQTMQRRRDVRTTNAAPWDLLRARRYESVLGLFTLSRPSFSTRPCPSFFLSSFVIPLLFLVLSYPSCSSPSFPPPSPSSSFFSLLLCHPFLFFFVLFYLPPLLLWHPLLLPFLHFHPLFLLHPFFLLLFRPCFTSLFCLSLLVFRLFHPPSFPLPFPSLSSFSHPSFFLLPFYLAHPSSFFIPLFSSICSCYYPSLRLFSHPSSPLSFDILPLLLSPPSFPFPPFPFPQVTHSLSLPSFSLHFPPPSSILSHVTHSSLPLLPPFPSLLMSHTPSPSLLPPLSPSLMSHTLSLPSSFPSSPHVTHSLSFPPPPHFPSSPHVNTLPLPSPSPPPFPILSSCHTTPLPSTPSLPPPHPPSSPHVTHSLSLPPSPPSSPILSSCHTSLSLPLLLSPPSSISLLMSHTPSPFHSFSPPPFPSSHVTHSPLPHPSSSPLIPHPLLMSHTPSPFHSFSPPSSPILSSCHTTPSPLPTPSLPPLIPILSSCHTLPSLPLLLSPPHPPSLLMSHTLSLPLLLSPPHPTSSPCHTLPPFHSFSPPLIPHPLLMSHTPSPSTPSLPPLIPILSSCHTLLSLPLFSPPPHPPSSPHVTHSLSFHSSPPIPLPPHVTTLPLPYSFSPPHILMSQHSLLPLLSPSSPSSPHVTHFLSPSTPSPPFPPSSLMSHTPLPSTPSLPPLNPPFLSSCHTLPLPSTPSLPPPHPPSSASCHTLPSPFHSFFHPLIPILSSCHTLLSLPLLLPPFPHPLLMAALSAAPAVARPGQGHGNRWRSSLQRLFSDDPAITIMRRDVRVADLYTIFLGQNACASSLLSRSAIPEANTLQDKAPTKVNTAALCQHGPQRSNIFKEDLPFFEESACILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSZ0</accession>
    <name>A0A423SSZ0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative homeobox protein aristaless-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_014607</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002822">
        <property type="protein sequence ID" value="ROT67317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSZ0"/>
    <dbReference type="STRING" id="6689.A0A423SSZ0"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000679">
        <property type="entry name" value="Homeobox protein aristaless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000047">
        <property type="entry name" value="HTH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050649">
        <property type="entry name" value="Paired_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329:SF543">
        <property type="entry name" value="FI01017P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24329">
        <property type="entry name" value="HOMEOBOX PROTEIN ARISTALESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00031">
        <property type="entry name" value="HTHREPRESSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="175"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="439"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT67317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="499" mass="54862" checksum="3F116FED55F77403" modified="2019-05-08" version="1">MLGERRHVGGHVRGQEGAPTHATSPTSHAPAPRTPAGTPPTPPSPPPAPSQEPLNFSRPKPPSSPPELAPPPTSLHARLGLEMARAGLGGGGGGRLGMLGEHHGRVGGLVPPLLPASSLFPHLNFGLGHDDGEERGLKRPLEEDLEPHHLDLSPFEAHHQRPITLQPPHLEEPRRKQRRYRTTFTTYQLEEMEKVFLKTQYPDVVTREELAMKIGLTEARIQVWFQNRRAKWRKQEKAAAAQAVFQPLLPLMRDPRASAAAAYRYPLLGHLGSPLLYPSSFHALLAQLSAHHKAETAQEGAHQKNENAPDDAHVSAGHNGPSDSDRHETPSKRGDQHALTEPQGTQMEEKEEEGEEDEEKDEVAEELRQAEVSAQGRESPGRGGFPGLDPKPSEVPRPPLDVKSLATLRALDQYRTLDLRALEDYRRALELRTLEARAAQYGPHMHQEAPNHQPSGRSTPSPGPSPSTHTPPESPACNEETLFGKRPEYNIDSLLKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUA2</accession>
    <name>A0A423SUA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002758">
        <property type="protein sequence ID" value="ROT67785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUA2"/>
    <dbReference type="OrthoDB" id="6352820at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="144" mass="15873" checksum="401B1CD78D2AB994" modified="2019-05-08" version="1">MLDCPGSGNFLYWLLHGRGKAYEPLSQSEEFTSVKVYHAGTHLCVRITGGDVMTAYPVDLAVRPHPPADMWNEVYKYKFGAGLIAALVCAAIFGLSCLVYKKRWRPEEEHDTAPIVSQGYDNPTLSKDEENGESTHIASATHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVP6</accession>
    <name>A0A423SVP6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002695">
        <property type="protein sequence ID" value="ROT68290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVP6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="45007" checksum="95296A4BB2B61250" modified="2019-05-08" version="1" fragment="single">PTGRSDFIRNKIKVDVERRTPSQHHHGNSCTERHSQTARALEPKFHYKTIFHVFYAATYAARLDPLSNLSLLPTSYRALYWLLSEARFNRPGRSRHNDTMRAASSQNVLSNRTVDRPFCLMSPPLSLTTPTVHSPLVPFCPPVCLAVPNRPLISSSSLIFPSLFLTSSRPSPRPSSCSLTSSLRPFFLSGLLCNLAFKPSYELIEGSPNTPRYPPISPPARSCILPLLSFTLCAAPSPRCPYLSLLVALTPHTPSLISFESRPLAPLLSFSVSFLPSSSPLRTSPSPSPLRPASLLPSLSPLPSFPHFPLLHRASFRKPFSFRTIFCFRVVFSFQALLSSRVSLHTSPSLLSLALLLLPSPFISFLPTFSSPRFLLAPALPSSPRPPPTPLFYTLTALLALLTPESLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY95</accession>
    <name>A0A423SY95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_012621</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY95"/>
    <dbReference type="STRING" id="6689.A0A423SY95"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4" id="KW-0807">Transducer</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="160" mass="17619" checksum="A6A05F6E1B883AC0" modified="2019-05-08" version="1">MLACGTDYLTETELSRSYLYVYSVWVYLFPLAYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTCAHCHSSFLIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACATDGRDGGSDAASTATTENAEKTESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZS1</accession>
    <name>A0A423SZS1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002554">
        <property type="protein sequence ID" value="ROT69538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZS1"/>
    <dbReference type="OrthoDB" id="6374921at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019525972" evidence="1">
        <location>
            <begin position="20"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="48106" checksum="62F040D1350E3F63" modified="2019-05-08" version="1">MRVLLLCLVVGWSLEEAMERDPRGIYGNRIDIQAGFFPAGTPGPVLVTPGSVQVTPGPLPVTPGSINVHPGPALVHPVPPHIHPIHVHPVHTHGACPPTVIYNTHVKYSTIVFPSVTTVGGAQTQTQTATSTQLITSTIFSNVGSNQVTTQIVFQTRTVTTTQGGFGTQFVTVPGPITFVTRTEEVLSTLTQGQTVFVTETRQVSTTFTITTYSNIVIPQPVFSTIFVTNTQTRTETLPGQTQTIQSTVYSTTVSTVFLPGQDVTSTRTIFSTSLVTQTITQGGQTLIITSTQFVPVTSTIFSTTAITNTQTRFVTSTLFTNGVTTVVSVQQVPVFNTRTVTAAGEITSTIVSTQGIGSTATIDTTIDTTVTLSGGTSVVTATSTALKTQLVPGAVRTVYRTHVVYHTNLITSTVLNRYYKTLNATRTLPVKCKTGYGHPSPTPAHKPWGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZY4</accession>
    <name>A0A423SZY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative GRIP and coiled-coil domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_011958</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002517">
        <property type="protein sequence ID" value="ROT69797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SZY4"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.60">
        <property type="entry name" value="GRIP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051841">
        <property type="entry name" value="MT-Golgi_org_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18902:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18902">
        <property type="entry name" value="NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="7">
        <location>
            <begin position="1271"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="539"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="611"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1169"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="656"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1220"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="464"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="539"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="612"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1190"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT69797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1344" mass="153848" checksum="9F62F8407EDB3170" modified="2019-05-08" version="1">MGAKKGRRYHPAGEVTAELKRVKAASKSVEAEEELRKKAESEAEALREMVTDLTEGKVAQTTKIESLQRQLRAASSEVDSLHELKAALLGERDKQEAETSKLLTEYQKTREELEQIKVSSTKKIELLQKTWEKEKHILQEKVENLEAQNSQVDILKTKCKKLVQEKAGLEEELKKQQVLVAKGVKMQGEVLALKEEKKAADIILETTQKQKKALEDKLKSFESQVTDLKKAKEKDEKNSKMELGKVQELEKRLGEKDLALSEAETKLKDLTNKLEDMERDSQKEEIVSNLRKQLENITEEKTNLDKKLEEVTVQKEHMEKSHRDQSEEMASLLKKEEELSTERNLLQKEKEAVANNLEDLKREFTTKEKIYLDEKHELEKKIVLLSEEKISLEKEFAAMSQSRKSNEEDFSSKRKELEEQIHNIMEENASLKLELEDRKGENATLQENIQELEKKIENLGSDTLRQEKEASDKEVKEAENQRLQLNSSLETSANRCEELLTELNQMNNVLRERGERISRLEAANKEKTEQLEATSKQLQELQNKMSSSEAELASKQEQLQTITEKLQSFSNDSPPPATAPDNQQLEKLEERIKELQQERDVLKKTIQGLESELSSARESTNQAQDAQSEAMSTSTISRAEDTQRMKELEDTFEERYMKLKSVAIKLKKRVAELTAQLNSSEESRSRLATEKDDLKKKFDMGAKDSMKTVSKNIQALQGEIDRLQDEVDSKVKELKDTGKQLVAATEQLAAAKSDLAKMQEENAVIYRTVKDSKTKSLMDLEMRDYELTVSELQGQLAEKDTNITELQAEIEREKRRSGSLQDQLVHLSTQEATERERAEKMKKLLLDHKTQLAELRQVQEVQAAVQETDRVTIEQLTQEVEKQKLVLSEISIEKTRLEDALRKSKAVADHQIEVLEDQLSKHKLEVSQLTSELKTVKDEFEGYKVRVHSVLRQKSRAPDIDVNELKTERDQLQSDYDAAQLRIQQLQSEISAVKAELSYLQSEKDGLLRQVSSISEELTKREASHQEKVAKLESKIETKTAEYQLIIANMSIQNETMSNSFKKQLETLRETHTHEVEDLTKKLEETEDKLWQLKNNVNTVPAPSANASNSLSPYAGVPHTNRHELETNTTAAHHNQHRRQHSHGSEENRIDITNMIREEGEGSEWVEPVHHSPARPMGYSPPPLEQLINSPLPSAPSQQPPQDDTVSVTSVATDATLKEIDRLESKLKSGEMRIQQLTSLLHESEAENAKLCQLADALKEEIRRSARNESREKHMENMEYAKNVILKFLMLRNNEERKHLVPVLKTVLQLSPQEVSQLEQMAVGTEEGASNGGWSDYLHLWSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T189</accession>
    <name>A0A423T189_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_011497</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the kindlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002449">
        <property type="protein sequence ID" value="ROT70215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T189"/>
    <dbReference type="STRING" id="6689.A0A423T189"/>
    <dbReference type="OrthoDB" id="10057618at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030055">
        <property type="term" value="C:cell-substrate junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005178">
        <property type="term" value="F:integrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007160">
        <property type="term" value="P:cell-matrix adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14473">
        <property type="entry name" value="FERM_B-lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13205">
        <property type="entry name" value="FERM_C_fermitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17096">
        <property type="entry name" value="FERM_F1_kindlins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01237">
        <property type="entry name" value="PH_fermitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019749">
        <property type="entry name" value="Band_41_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035963">
        <property type="entry name" value="FERM_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019748">
        <property type="entry name" value="FERM_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037843">
        <property type="entry name" value="Kindlin/fermitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040790">
        <property type="entry name" value="Kindlin_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037837">
        <property type="entry name" value="PH_Kindlin/fermitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16160">
        <property type="entry name" value="FERMITIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16160:SF13">
        <property type="entry name" value="FERMITIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00373">
        <property type="entry name" value="FERM_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18124">
        <property type="entry name" value="Kindlin_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00295">
        <property type="entry name" value="B41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47031">
        <property type="entry name" value="Second domain of FERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0130">Cell adhesion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="339"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="148"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT70215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="643" mass="73670" checksum="AF3C4C21CE00E138" modified="2019-05-08" version="1">MDIAVDWSDHALWWPKKNVWLTHTRSTLDQYGVGAAAQLEFTPMHKNLRVQLPDLRYMDFRVDFSIKTFNAVVQLCKQLGIRYPEELSFCKPITQDNLKYNYSEKMIKKKSTAATKNGTPADTNSFIANQSHNSSNGSLDRSAASHHMPNSPTRTPIGSPTGTWRFNSNGVGSLNNTIDSIDGSDEFVASLANSPIHPSEEARNRLVRPKSLLERARMNVAWLDSSLSIMEQGVREFDTLLLRFKFFSFYDLNPKYDSVRINLIFEQAKWAIMNEEIDCTEEEMLMFAALQLQVNLQVNQPQPDMNSGGEDDIDRALSELQMSLEGSHVSSTPADIMHIPELADYLKFMKPRRFTLKGFKQYWFTCKDMNLCYYKTSDGTNEDPIERISLRGCEVTPDVNISQQRYGIKLEVPASDGMTDYLIRCSSEEQYARWMAAMRLASKGKSLADSSYDSEVKSILAFLSMQHPAPAPVINPESLDIQPELYLAPRFVRRIRGKAVQRILEAHANVKDLPLTEAKLQYIRAWQALPEYGIALFLVKHMGHKREELLGVAFNRIMRMEPNTGDHIKTWRYNTMKAWNVNWETRHMMIQFEEENVVFSCLTADCKVVHEFIGGYIFLSMRTKDANQNLNDELFHKLTGGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T253</accession>
    <name>A0A423T253_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002411">
        <property type="protein sequence ID" value="ROT70580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T253"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="45337" checksum="19D625595769671E" modified="2019-05-08" version="1">MILLFLVLILSSLLLVVLLSFSFSSFSSFRLPSPLLPSDDTPLRPHASCFFVGSHIPPSHFTTSPFSLSPFPPSPFPPPSPLLPSDDTPLRPHASCFFVGSHIPPFPFTTSPFSLSSLSSSPLLPYSLPMILFFLVLILSSLFSHIPPFHFTTSPFSLSSLSSSPLLPSDDSLRPRPSLPFVGCPSLFFLFLLLLFSLTPLLPSDDTPLRPHTSCFFVGSHIPPFHFTTSPFSLSSLSSSPLLPYSLPMILLFLVLILSSLLLVVLLSFFFSSFSSSLLLPYSLPMILLFALMLLAFLLVLIFLLPILQLSLLSILPSPLLPYSLTPLLPSDDTPLRPHPFLPFVGGPSLFFLFLLLLFVFLLPYSLPMTLLFALMLLAFCWFSYSSFPFYNFSLLSFSSSSSFSLTPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3A5</accession>
    <name>A0A423T3A5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002367">
        <property type="protein sequence ID" value="ROT70944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3A5"/>
    <dbReference type="OrthoDB" id="419734at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="19060" checksum="2AF69F57A055B76B" modified="2019-05-08" version="1">MLYLMLIARRPSPGPLSRIRNFCVHVDGDVSSQRKDLKVGERRRARNCLRMVCVVNALMPVLATPVYSLVYNATVGVFPGTVFVLLAALCAVICCLAVWLYTRFDQQTAATSRAQATEWHVGSRGPGPRWRRRDYAAGLRVIRAASRRLCCRTTTLAVSFGGPSANLFLPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T457</accession>
    <name>A0A423T457_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin conjugation factor E4 A</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_010453</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01002324">
        <property type="protein sequence ID" value="ROT71244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T457"/>
    <dbReference type="STRING" id="6689.A0A423T457"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16657">
        <property type="entry name" value="RING-Ubox_UBE4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF16">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="14">
        <location>
            <begin position="988"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00040077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT71244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1075" mass="121758" checksum="9331DF9507A4105A" modified="2019-05-08" version="1">MSKDLQSNPFAALFSTLKEAEQFQSEHQKQQNDDDNDSQSVLQQPGEREEPSRTSPVDGDAITSFLESLLLVTTREGRHSRPLVLLPDAGKLDTESLQFVMFERLLLESPDACLVGDSNRGREEAARSEVVVYLCEVYYRCWAVRSSPHFHLAQQVQAAVITNLATALEQPELYGGQQPDRQLIDVLLRGLGREAAVEDLTQKLLNHLADQGTPVPPLFDEVIVNITKKLMHCSLMTVDYQLVDVLDFYASCPHIAEILTKTPDKVTQDRSGRGYQNTPLGALLSISCLPKHPAGQFEFFEKPSSQPNHTHKDTENSIWIAQNTINARLHKIFYSLLKVSPKAKDGLLTWVESCLESNSGRAGLWHVQGGNPLAAAVYVSDGFMVNLGVVMLQLAQPFTQDLNTAKFLKIDPTYCSAPRMNNENGVVGAYTGDLGRQTTLIPQQEDKPPLHPKQYSFISSCFFLTHRALHLGVQVVQQKLHKLSQELGRMQHELQEASAQGSPATEMMRSHMETRTTNLLSFKAAIFEPVMVENLLQFLAATAEWLVQIALTPQDQPTLPTSLREVKAPLPEEVENHIYLACIPEFLVETLTETISAVRRYSAQVFESSTGTQVLPHLMSFIIVFMGSPHRMNNPHLRAHLAECLETLLPESTNTGGLLAGYREQLFTAHPAASHLVTALIHVFVSIEMTGQSVSFEDKFNYRRPMYEVMKYLKIMQYKNYVECAEILFTYICENMYAKICKQPVKKSKLLIIFSMKWESPKHRKSFTHLADEALANMEAAKPPLFLRFVNLLMNDAIFLLDEGLSYMSQLRESQMERDKGDWASLPTEQRAERERNMQHMMLLARFHNMLGGHTIKTLIRLTREIPQMFTHSTLVDRMAAMLNYFLSTLVGPKQRNLKVRDMEKYEFRPGEIVTDICTIYTHLFSDAAFCLAVSADGRSYSPKLFSQAQDVLCRIGRRGLAEELQTVAEKVEEAGQVQAEEDDIVADAPEEFLDPIMSHLMTDPVILPSSKLTCDRQTIARHLLSDQTDPFNRQPLTMEEVQPNTELKNRIVTWLEEMRSKRRNMQKEKELKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T493</accession>
    <name>A0A423T493_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002348">
        <property type="protein sequence ID" value="ROT71048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T493"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="514" mass="57015" checksum="2C0532A18AFA8CCF" modified="2019-05-08" version="1">MGPSKKSGERLVKDHGRNITSFAQPTPLGARSNSRDLLPDVQSNNQAYVATAQERSHHDQPVPDNNDLGAEAVGPRTSSREVSFSQYRVTDEENHLGLSMFGEIILRFDAMIRELKEEINSIKEDVRANRDRLTDAELGNNQTPRRAPGVRDGTGTLPSSVPFRGPSISHAPYSAAPMMVMPSSGISLFKAEISASHPLQRSQELEAWMKQIENVTQPSTGEAMCQMARMMCRGTPEPHCYKGNGIILMQSVTRIFSPAECFYKVSLNGCVKLWRRETMHLQTNSCIVLSSCEIPESAFHTYNHAHNRRDTATASLTAVHEFGRKDAVFAVVNVDTASLCPDDRSDRPFQQRQGNSRGSSSAGVTRISIALQTEDGMQPAVTPVENVALLDEQAVRQAQRDDPTWRLLIALLTDGALPPPGAPLPLDDFEIKDELLYRLRRLPDRLVHQLVVPTTLQGLVIKQVHDEAHPGVYRTYCNFSTLAKFVNDARALHYDGASFRMHQTSITPSRIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6H4</accession>
    <name>A0A423T6H4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative still life, sif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009568</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002214">
        <property type="protein sequence ID" value="ROT72031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6H4"/>
    <dbReference type="STRING" id="6689.A0A423T6H4"/>
    <dbReference type="OrthoDB" id="8059989at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00136">
        <property type="entry name" value="PDZ_canonical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01230">
        <property type="entry name" value="PH1_Tiam1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000065">
        <property type="entry name" value="T cell lymphoma invasion and metastasis 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003116">
        <property type="entry name" value="RBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043537">
        <property type="entry name" value="Tiam1/Tiam2/Sif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040655">
        <property type="entry name" value="TIAM1_CC-Ex"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46001:SF3">
        <property type="entry name" value="PROTEIN STILL LIFE, ISOFORM SIF TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46001">
        <property type="entry name" value="TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02196">
        <property type="entry name" value="RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18385">
        <property type="entry name" value="Tiam_CC_Ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00455">
        <property type="entry name" value="RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50898">
        <property type="entry name" value="RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="81"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RBD" evidence="5">
        <location>
            <begin position="360"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="443"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="581"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="622" mass="69684" checksum="5665B69B5ABB72C8" modified="2019-05-08" version="1">MPLHPVMALSPSYLEKDSKSVISPGGECPWSSGPGTPMSDDDRMSLTTAVSEDEEGESVHNSPYKAPRAGTTAASFNCTGAVRKAGFLSVKKWLLRKKHQIELARKRGWKGYWVCLKGTTLLFYPCDSREGRSVEAAPKHLIIVDGAIMQPIPEHPKRDYIFCLSTAFGDAYLFQAPCQVELENWVNSIHSACAAAFARHRGKTGTLHLLQEEIFRIDRAIESDSKLKHMAELQLSVVSDAESKQQIMGQIKQWEENLERLHCEQFRLRCYMASLQAGELPNPKGLLTHVSRTTKTTLNRLGVFTVSSFHAYICARSPSLLNNLLAGRGATKRRAPMLSRSNSVSSRRSLQMQQQLEGEKQYKVNLPDNQTVTISIKDSMTVEEFLVAASGRKNLNPMEHFVRVKKRRELEETNYFVPHRTDLIENYLATHEVVEICAKILYQVELSRSSLDHMWGFSVEAELIENSERQDELCCYISRVEDRSTAMQNGIIKGDEIMVINGAIVSDLDMMYIESVLQEELALCLMMRSSRTDPPDLASLMKTTDEIIESLVCPPPPTETSLNEEMISRMIVPAPTWSKAILPGKEPASPDGFPPPASDTSERSNVSSLEIENFLRVSNTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8P3</accession>
    <name>A0A423T8P3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002111">
        <property type="protein sequence ID" value="ROT72804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8P3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="460" mass="52726" checksum="C3E1C6A8ABECE682" modified="2019-05-08" version="1">MGPGYVRWDQLSPGVGGIALRRCVEKFIEGRFCLREDLPFVARILRGTYPSWHVSFVAYRARILCGTCIPLIPRARITYPSWHVSFVALIPRGTYPSWHVSLVARILRGTYPSWQVSFVACIPRGTYPSWHISLVARIPRGTYPSWHISIVARIPRGTYPLWHLSLVVRILCGTYPSWHVSFMAHIPCGTYPYPSWHYPLGTYPFWHDPLWHLSLVARILCGTYALAVALSLVAWRILRGNRTYPSWHVSFGTYPRGGTYPSWHTYPSWRGTYLVPSARSLGMARIPRGMARIPRGMARIPPCTYPSWHGTYPLVAWQACSRGMARISLVAWHVLPWHGTYPSWHAVSLVAWHGIPRGMARIPRAWHPWHGTYPSWHGTYPSWHGMYPSWHGTSPSWHGTYPSWHGTYPMARGPRIPRGMARIPRGMARIPRGMARIPRGMARIPRGIVWHVSFMKTELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8W4</accession>
    <name>A0A423T8W4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nuclear speckle splicing regulatory protein 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002092">
        <property type="protein sequence ID" value="ROT72889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8W4"/>
    <dbReference type="STRING" id="6689.A0A423T8W4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="503"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="605" mass="67212" checksum="4E1101CD8D3E0CB1" modified="2019-05-08" version="1">MESNGGEATPPRNDPERWGTTRNDPERWGTTRNETMGRQGTTRDDDGDDKERNDGGRQGTTRNGGDKERDDGGRQGTTRDDGGRQGTTRDDGGRQGTTRNDGGRQGTTRTMEDDTTNGGDKERPGTMGDDKDDPDDGDDKERPGTMGDDKERPGTMGTTRNDPERMADDKERPGTMDGGQGRPGTMGDDKERPGTMGDDKERPGRWGTTRNDPERMAGRQGTTRTMGDDKERPGTMGDDKERPGKWGTTRNDPGRWGTTRNDPGRWGRQGTTRERWGTTRNDPERMADDKERPGTMGDDKERQRPTERNDVGDDKNDPERWGRRWVGTMGDDKDDRNGGRQGTTRNDGDDKERPGQGTTRNDGGRQGTTRNDGGTGTTERWGTTRNDPERWGTTRTTRNDGRQGTTRNEWGATRNDPERWRTTRNDPERWGTTRTTRNDGATRTTRNDGGRQGTTRNDGGRQGTTRNDGGRQGTTRTTRPGNDGDDKERPGRWGRNDPERWGRQGTTRNEGTTGTTRDDGGRQGTTRNDGGWDDKERPGTMGDDKERPGTMGDDKERPGTMGDDKERPGTMGTTRTTRTDGGRQGTTRNDGGRQERPGTMADDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T975</accession>
    <name>A0A423T975_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002079">
        <property type="protein sequence ID" value="ROT73033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T975"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT73033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="108" mass="11843" checksum="3C53963C7B8C4D1D" modified="2019-05-08" version="1">MFRQVAGSESNECVFSRGTPTHARQSLSLALPCPAPSPCSIIVYEDETLTQTPAENAVLAQVDVTTFLESSKFVKMDFHLKSDGSLHVTLQEPKSKVNQSFIIEADRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9L8</accession>
    <name>A0A423T9L8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002061">
        <property type="protein sequence ID" value="ROT73149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9L8"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015318">
        <property type="entry name" value="Znf_GAGA-bd_fac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09237">
        <property type="entry name" value="GAGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="391" mass="41976" checksum="C10EAF9004132EE1" modified="2019-05-08" version="1">MSVMWHSTVLPGRNTRRARLQWSDGILVGELRLHVSALMAIANAVQATAPSDRPIKCPLCQSIIKQARNLRRHVFKRHLPAAKRGEITEADVKNVLERKLKAITVTPLTEEELRAVQQRTRRKGMKTPRKKKGVASLPDGVNGSNINESEVTIRKLPQKKDKKDKVGGITGLSSTSTNLTGETSREGREDILQEALAARDKDIAPQDEVMDLATTQQQLPPISVVVSHSGHSGVQVGTQPMSLTVTQTAGGVHARIPAEAALGAGVRLQADSPLPLHRDLPTMPPMAFEPQVTISEGMVTYHTTSPSQVLTQTTSSSPSASGYTPASYWSPPGVAGLPAGTFQPHAECVRSSALGVLRCGRAHGTACLARAHAAAPTQTLPVKVSLSLFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFQ7</accession>
    <name>A0A423TFQ7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_006177</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001791">
        <property type="protein sequence ID" value="ROT75286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFQ7"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015375">
        <property type="term" value="F:glycine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00610">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00754">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5 10" id="KW-0769">Symport</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT75286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="662" mass="74606" checksum="7433B66239F85D6E" modified="2019-05-08" version="1">MPRKTGELETDATEIRITVNRADDDKSICLNDEDRGVWGNKIEFILSCLSFAVGLGNIWRFPYLCYRNGGGAFLIPYFSMLCITGLPLFFFELSFGQYGQEGPITIWKAVPLFQGIGIGMFMIAFFIALYYNIIIAWAFFYLFSSFTAELPWQSCDHWWNTAACRRFDTKNCTANSGLMAPNGTCYLESDVSKEDWQLLNETSESMKLPADEYFHNFMLDISEGFHDDEGHTLQWRLCLCLILSWVVVFCGLFKGVTSMGKAVYFTALFPYAVLIILFARAVTLPGYLDGIAFYITPEWGKLLTARVWADAAMQIFFSLGPCWGGLITLASYNKFNNNCLRDAIFIGVANCATSFFSGFVIFGIVGFMAFELGVPVKEVAAQGAGLAFVAYPEAVARLPISPLWSILFFVMLLTLGLGSQFTIVQTVITCLVDVFGLRRHYKTMCCVVCTVGCILGLAMCTRHGMFILQLLDNYSGTYSALMIGCLELIAIMWVYGVDNFMDDVKSMLGGYPTGYYYWRFVWTYLTPASVFNILLFTFIDYSPSSYSNYQFPLWADILGWCISFSCIAAVPVRAIWLILGKSGPIKARIQQLCRPAHDWGPAGRKHTDDTTLNAIDSKTPLANDEELYEMERESPYLTRVSEEWEDEEDDGLHMKVPSRTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TGI8</accession>
    <name>A0A423TGI8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative WASH complex subunit FAM21C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005867</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001756">
        <property type="protein sequence ID" value="ROT75579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TGI8"/>
    <dbReference type="STRING" id="6689.A0A423TGI8"/>
    <dbReference type="OrthoDB" id="751084at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029341">
        <property type="entry name" value="FAM21/CAPZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15255">
        <property type="entry name" value="CAP-ZIP_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM21/CAPZIP" evidence="2">
        <location>
            <begin position="74"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT75579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="361" mass="38780" checksum="EE1E1C3023E735F6" modified="2019-05-08" version="1">MFGGGGLGGSELFAKVNQRKSMLGETESDSDGDSKIGSASAPTHSVEIVKEDRKVPKMSPASKTVVNPTPTASTLPSLGVKFGGQENSISFDEPVTTTNTLESLNKSRVRGSVKRRPPSRAHRKGAAIDSSQTNTLTIPSVAQTPSDRVPVPQETNTRKLNEKDAAIESPSHSDPPVEDQIFSSSENEDDMFRENKAKNVNRIERSVQQIHQTHEVENGSNTTPSKQAEVQGELEEDLFSKLQNASYTRKSQNLVKPDKSQPSSLFGDDDSDEDLFGASNSKLSSHKASKSAVQPDVSKKESKPVVSQSLFGDDDDDIFSSTGAVGKAEPSAVKKMSTSKSKTSLTSTSEPFDDPLLGPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIF1</accession>
    <name>A0A423TIF1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mesencephalic astrocyte-derived neurotrophic factor homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">MANF/CDNF-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_005182</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARMET family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001678">
        <property type="protein sequence ID" value="ROT76228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIF1"/>
    <dbReference type="STRING" id="6689.A0A423TIF1"/>
    <dbReference type="OrthoDB" id="5597848at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071542">
        <property type="term" value="P:dopaminergic neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031175">
        <property type="term" value="P:neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.225.10:FF:000003">
        <property type="entry name" value="Mesencephalic astrocyte-derived neurotrophic factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045333">
        <property type="entry name" value="ARMET-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019345">
        <property type="entry name" value="ARMET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045332">
        <property type="entry name" value="ARMET_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12990">
        <property type="entry name" value="ARMET-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12990:SF5">
        <property type="entry name" value="MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10208">
        <property type="entry name" value="ARMET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20145">
        <property type="entry name" value="ARMET_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="ARMET N-terminal" evidence="9">
        <location>
            <begin position="150"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="ARMET C-terminal" evidence="8">
        <location>
            <begin position="240"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="287" mass="32155" checksum="B1E7D72618AA3CD4" modified="2019-05-08" version="1">MWSSCGPDIGTALAATEEIDAERSAAGAESGVTSTTMFSKFSNVSYSYLGTSQLDWVTVCLAGCREMWRMRRMPVRDGQSPPDNCVKAGVDVAERTCARSSSGFSSLATSLVRQEVTSSPVEHRGLSEDRRVERGTCVKPFIWTLCIGSQKVSQTFTDSEKSNPKSIETRFKEACLSSKGKENRFCYYLGGLEESATGILGEMSKPLSWGMPVEKVCEKLKKKDAQICELRYEKQIDLNNVDLKKLKVRDLKKILNDWEETCDDCLEKGDYIKRIEQLMPKYMHGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ77</accession>
    <name>A0A423TJ77_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001648">
        <property type="protein sequence ID" value="ROT76520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ77"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="853"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="900"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="945"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="962" mass="106492" checksum="0F10ECD5537867A7" modified="2019-05-08" version="1">MSDSRVSLFPLAVLQYLFSSSFPGVTTEYQLLYPKPCQINAPRHHLLLFLPNAHHMNQSLFPAHLEKHPFFPAAQNRCFLSRAQQPSLSNGALNLQNIPSRRQNRSPFPAPRTILISQRQNVSFSGGQTPFPGAPEPDPFPAPQNVPFPDAPESIFSFLPVRPDTHSLSAGVPPRTVPFPAPRNHPFPAAQEPSLPGATLTFSGAQKHLFFRAPQIISFPSAPRTSLFPGAQTTYPFPGGPEHPFSRRQNSSLPPRPGTFPFPQFLPCRPFPFPAPRIISFFHPALKTIPFPAPRNHPFPARTSFYPFPFPGQTIPFPASRTIPFPGAQNLPFPAPEPSLPWAPRTTILSRRLEPSLSRRPDHPSRSFPGAQNHPFPGAQKPFLSRRPSLSRPRTIPFPPQNAFPAPEPSFPGDQNHPFPGAQNHPFPGAQNRSFPGAQNHPFPAPILSRRLEPSLSRAQNHPFPFPRRPEPSLPGAPFPAPEPSLSRRPEPSLSRRPEHPFPGAQNHPFPGAQNHPFPAPRTIPFPAPRTIPFPAPEPSFLPSGAQNHSRRPEPSLSRRPEPSLSRRPEPSLSRRPEPFLSRAQNHPFPAPRTIPFPAPRTIPFPAPRNHPFPAPEPSFPGAQNQPFPGAQNQPFPGAQNHPFPGAQNHPFPAPNHPSRRPEPSLSPRNHPFPAPRTIPFPAPRTIPFPAPRTILSRAQNHPGAQKPFPGAQNHPFPGAQNHPFPRRPEPSLSFPSGAHRTILSRRPEPSFPGAQNHPFPRPEPSLSQNHPSRAQNHPFPFPAPKTIPFPAPEPSFPGAQNHPFPGAQKPSLSGAQNHPFPGAQNHPFPAPRTILPGAQNHSFPGAQNHFPAPEPSLPAPRPQNHSFPRRPEPSLSRRQNHPFPGAQNHPFPGARTVPFPAPRTIPFPAPRTILSRRRTIPFPAPRTHPFRRPEPSLSRRPRTIPFPAPRTIPFPAPQNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TK75</accession>
    <name>A0A423TK75_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_004508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001598">
        <property type="protein sequence ID" value="ROT76870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TK75"/>
    <dbReference type="STRING" id="6689.A0A423TK75"/>
    <dbReference type="OrthoDB" id="429143at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1400:FF:000003">
        <property type="entry name" value="Pyruvate dehydrogenase phosphatase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.110:FF:000004">
        <property type="entry name" value="Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032503">
        <property type="entry name" value="FAO_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF15">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16350">
        <property type="entry name" value="FAO_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="2">
        <location>
            <begin position="48"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase central" evidence="5">
        <location>
            <begin position="411"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="GCVT N-terminal" evidence="3">
        <location>
            <begin position="470"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="4">
        <location>
            <begin position="788"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT76870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="898" mass="100794" checksum="74A19ACB04CB0736" modified="2019-05-08" version="1">MSQQCHTSADILKGSWYPPHQYHQHDQEKGMHISSTLPLDESPPKKAKVVICGGGMVGTSLLYHLAELGWGSDTVLVDQARIGAASSWRGSGFLGGVKLIKTEMNILRTSKKLVKELSEAGHDTGWKQCGSLHLARTRNRMTHFRKMKAIAEARGTECYMLTPEEVAKKCDILHTSDILGGMWVPKDGACDPYKLCYTLLKLAIEKGTHVVEKCQVTRIIVHNQRAVAVETTKGIIECDYVINTGGLWARNVGQLTEPHVKVPVHPAEHYFLYTYPIEEIDPQMPAIRDPDGNIYLREYNGGLMGGGFEKWAKPAFEHGILPDDVEERDQLEDWDHFHILLKEMLHRIPVMKNAVLGRLYNTAYGFSPDHRWIIGMSPELSNYFVATALRSGGSNAAGGIGSLLADWIVSGISPMDAYDLDILRFLPAHNNRRFLLDRVREVPGLHYGIAFPFGDCETGRCIRMSPIFPKLKAAGAVFGQVMGYERPSYFDPAKSLDSKDAGDSEHSEHSAPFHMAYSDTWTKPHWFDFAGQEYAACRERVAILDYSSFAKFDIWSKGNEVVQALQYLCSNDVDIPVGGIIHTGMQNSHGGYENDCSLARIAPNHYMMIAPSIQQTRCSTWLKRNLPGDGSVVMSDVTSMYTAICLMGPLARCVLSELTDIDLSTKAFPFFSFKELDVGLANSIRAMNLTHTGELGWVLYIPNEYGLHVYNNLVSIGKKYGMRHAGYYAMRSLRIEKFYAFWGQDLDSTTTPLECGRGFRVKLNKDIDFIGREALVQQKKEGVKRLYVQLQLEDHDIEVDPWAWGGEPIYRDDRFVGVTTTTGYGYTLQNLVCLGFVRNFNEKGEMDFVTPEYVMAGNYEVDIGGVRYSATVRLRSPTLPTKFPEPQLDRYLATRISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKL1</accession>
    <name>A0A423TKL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001580">
        <property type="protein sequence ID" value="ROT76996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKL1"/>
    <dbReference type="OrthoDB" id="10009867at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="529" mass="57569" checksum="296C62920B95DD90" modified="2019-05-08" version="1">MPVPPTSPSVGRYSSYSSYSSYRTPSSSSYLGRTTSLDRSSYSSSYGGSYTSSYSSKYSRPPLPSYSASTDTYRSSRSLRQSPARPAYSRLSSDSHIETTPYSSRYANLVDGKRDTSSSRDSGYGSRLTSRDRSVDLVNGNGVDTSHFGPSHSSYACNYRWEARERDKADAKDADQNGEDEKVCISDRIRAFETRSSARERLGLPAGRESALASLRDTGLSSSKDSGLSLGDTSLSRRRAARASDAPTRTSSVRKSSPEGVSRDAADENANTSSERRPSVTELCRKYDSNHNVTNGVARQEDEEDGSDGGSVCSGGPALEEATIRPTRKAAESTRTDSPITARVDSPAGGRVDSPSRLRVDSPARNHVESPSRSRLESPTTGHKDRAQRDSPLRTRLDTSTTRQDSQADRDGRSSPVLNGTIDKVSVPRDAPSAVSPSHLSSARFRDPSCRTQRSRPFIPFTTRPSSHARPLLHFSPTTEKRHRHHPIQHTHTDSFPIIASASTNDPYLAPSEAPEPGREIPGRSGESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLP1</accession>
    <name>A0A423TLP1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_003986</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLP1"/>
    <dbReference type="OrthoDB" id="6413415at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051560">
        <property type="entry name" value="MAM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282">
        <property type="entry name" value="APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23282:SF101">
        <property type="entry name" value="MAM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="292"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="460"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="653"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="861"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="148"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="922"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="637"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="841"/>
            <end position="856"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT77371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="944" mass="103643" checksum="1AE19FA840D6F67C" modified="2019-05-08" version="1">MNRAETHRPIPRVPLPSPHTRGQALEWKRPLSQHPSLGCPDVSPAEMEALIFASVWPPPLILSSTKLFSPSCVRDLEIVILISWGRQRRRGGEESAQNLTTLPPTHTVPRPFSAPTAPTRATRGLAAANQLRSPAACAYLRLPGSESARAATNGDGGAEWGKGPSPRAATGIVEGSSEVSGRDGCDALMLAWAGAARKPHSSARPPRGPATASDNTLGARFCRLGIYEPLRRGGLPQTHRHGLSATAVTTHSRTHYAHIQARNSSGGFLWPRRTKTVGRHTKGGLRLGGRDHPCDFETSDLCEFAATDLEGDFWAWGWGTNPDLNNAPEIDHSYGSADGHYVFLNHRSSEVKTDAYLTSLTGSSSGAMCLQFYHYMQGRDTWTGYLKVYVKNPSVNIIDISPVWMESGPKGDRWIMSRIPLIFGGQYHVVFVGNEGKEGDNSIIALDDVAMLQSQCPVAATCSFEDGLCDWQNELGYDGLDWVMNQGATPTQDTGPKYDHTLQTALGHYMYIEADDGSPNDYALLTSPSIAAGQYCFEFYYYMYGADIGGLAVQSVVNGVERTKFQAFGNQGQEWKLGKVTLKEEEEFTVQLRGVLGKGPLSDMAIDDTWTTNKACPVDPGQFLCADGTGISYDKVCDFIADCPGKNDEDLCGDCNFELGSCGWTFLNTNDNIWKRGGNMTEDAGVDFVYDHTLGTDAGYFVYTSEQPSDVQGPAVMVTNPLHNSHLQCAMEFWFRENSVIESGRHVHLTVNVNKDGQTSPVFFLVDSKNRDWMFASARLMDWQGEFTVQIEGQNDNGPADLTLDDIIFTGCALPVSSDECLPYQMKCAWTGLCIQPDLLCDNTNDCGDLSDEQNCGSYPNICDFEENQLCLWIQEPENDDIDWQYGSGLTPVGSRTFLTGPPVDHTTRLSVGHYMYITPSQPKRRKKKDMKTGALATQPSFDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMW3</accession>
    <name>A0A423TMW3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphorylase b kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003514</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; glycogen metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphorylase b kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001477">
        <property type="protein sequence ID" value="ROT77790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMW3"/>
    <dbReference type="STRING" id="6689.A0A423TMW3"/>
    <dbReference type="OrthoDB" id="5971574at2759"/>
    <dbReference type="UniPathway" id="UPA00163"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005964">
        <property type="term" value="C:phosphorylase kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005977">
        <property type="term" value="P:glycogen metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045583">
        <property type="entry name" value="KPBA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008734">
        <property type="entry name" value="PHK_A/B_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749">
        <property type="entry name" value="PHOSPHORYLASE B KINASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10749:SF8">
        <property type="entry name" value="PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19292">
        <property type="entry name" value="KPBB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="1 2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0636">Prenylation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphorylase b kinase regulatory subunit alpha/beta C-terminal" evidence="3">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="118" mass="13505" checksum="B3CB5444A5073B07" modified="2019-05-08" version="1">MSHSDLNFALAVQSLLNRIQHPEYRQIVVELISVIATILERNPELKFTHAVDLDQIVRDAFKMYMKDLGKEVTEDISYLYTVSEMGMKSYLARAVVNFMLKGDIKTNAEEGQTFCQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TN20</accession>
    <name>A0A423TN20_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative spatacsin isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001463">
        <property type="protein sequence ID" value="ROT77868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TN20"/>
    <dbReference type="OrthoDB" id="2018754at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030425">
        <property type="term" value="C:dendrite"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045202">
        <property type="term" value="C:synapse"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008088">
        <property type="term" value="P:axo-dendritic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007409">
        <property type="term" value="P:axonogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007268">
        <property type="term" value="P:chemical synaptic transmission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048489">
        <property type="term" value="P:synaptic vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028103">
        <property type="entry name" value="Spatacsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028107">
        <property type="entry name" value="Spatacsin_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13650">
        <property type="entry name" value="SPATACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13650:SF0">
        <property type="entry name" value="SPATACSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14649">
        <property type="entry name" value="Spatacsin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spatacsin C-terminal" evidence="2">
        <location>
            <begin position="2111"/>
            <end position="2470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="722"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1338"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1835"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1940"/>
            <end position="1961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2282"/>
            <end position="2325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1339"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1940"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2282"/>
            <end position="2297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2533" mass="283586" checksum="75C6FFDADD1CB9DF" modified="2019-05-08" version="1">MSAHHRNVNKLVVVKKLTDISYPIEQVLRAELESNNRGFLTLLGDGRLILTAWINKKVTSKIVEDASDACWQHGSESEVVIVCHNGALVRYSLHFDTGLSCSLQLSAPSLLSLIREKDSSVRSLRSPKIWGHTIEHILLQPQSDRLVLLATNAGGRPTAKGVLRTPPLRTAHLNNDKILAQPVTGSDLYEYDTKTCKIHEIVNLGLQRMGSDFIEWGTLAASLTGDTIAAVDSERHLYVTNFRHRVSLGRRGRVNRSRVTLHQLELPPLLYRASRHHTRNAPPASLLTLDGVAMLMDEDASISSLDSEVDLGELLGAMDDALKEQNMAKVTEVKALVEQGLSVFLSSCNHQEGWLGLAEMRAQQYGQLANLLLSYIPQYAECYESYSLALALKDLSRHHFISVREEMSNVLQYVDSESISQMVLQMTEQVSFYFRSVEQLQLPQEGSGHKELSKQHAVWGEKPMKEILEDALQRGLVKAAESYLQLKPWVYGAVTTNMVISTCIDIARQKETENSKAEILMNMDDCYNEALKQILHSSDDLFEVQVLGTVLGARSLLSVVETHAVNLVINIHRTLPDLLTLPPQVWTELVKLGDASADAVTGPMTVKQVSQWTPLSMMLVMTDLYACTADPEILQSVDADVMWQYLLHQHDIRNLKKWILLEFNGQDQDQEGDVTLREEQAWSDPAYRSPRRSQPTASMPETLGEISETKHLGPNLFSGPQYGSEFGSSPQSQDELSIESTSLGPGDADTWSVQSFEVHDRRDTLWSVQHFKPITQSMVDLVVIAKEAFVEVVLNILARYGVFITKEKKDPQLLMRRLLVSGAFELVSSFKGNHSCQVLERDIHTTLLKFFGDNDFVLPAYDYVEHFSPDGGNELLVDLEMPPWANLIVAFRKLGESHSKDTIYDLSLKNLSLLSEKCQNPEELHLPAFLTMLFAPSSSLENFITCNPDKLEATDEGEISSLYAILSKHNTTPKQVIEGLSLKYPYLEKLKKKTNEATLDVTMYDLLCGNVPYDIARLFTWQPGNKQGYDEDGKLPCFSDEELISNYGLQHSLDFMYYLREARPTYACAAIMTSMYLNKSKKKVEDVKGAIYGLALGCWPERAISAACVAVLLMTGLPANPLRTILAAAFQILQARNESCAKLKWEKRQAQEHLTTTEIKDLLHQLCEVSTRVTAAKMVLKMLEDCVMMALMEKAKEDQSALNERAEKEDTKKDDSTEKNKLSIEHVQTFMEGMRLCMEFCCIYELPWPTRLLKHLAELDQWLLFLASAQIYKFPRDEVLKAAESFRSIALREHMLFALTHIYYYREGREPRERSREGSRRTRSSLYSRIGIKVREDSLSPTQSSDENPRSTSPSEPEVSIIDDALSFTTTETCHDFGIDSWLSYRHNDIYSILLTCHQRENAASELVTAAVALNIPILCVFAACYERHNVFTCLSVWLYTQLPKAAKKTLHQHLIKSEIYMSLINDNSKLKQPEGNCCRTCDNNVLQALQDDLKWILLAHISKGSVDVAVEGLKIFLPNSPILSLLLAIKEVNGMCCKEKVEKYLSASASALENEICLESYAASGRREWSTRTMIDIIGKALDEFITNSHLQCYFLSAITAISQQPPFSSHNVNWTLIGQLCKALGSVKHQVTFLDLLWCFETGELKTYANSIVSCLSENRYFSEALSVSQLTSLPIFTIVCAQLRAEFEKNQGTVIENLSNLEDYLAKSHKRLCQESVPPEHAATCFISISKELSDPAMKYLCLQYVVIWVSKEDIPADLTDIKESLECEMWESYIQAILNKESNLSKGMIKPPSHLGVWPWEGQDGTSPLDRKLIITSAELKSEIVPQLVSEDKELKHKSQDTASTKEGDLGSPDRTRDINNDTPGKEEEREGESQSKNARDKATQYLVDMCIDEGMLSTAYRILVFFHQSNRNMETLLSLLGLADGSEVEEGGGEEKEACAEFRRTSPPQSVGRRGRTRSRGISVCSGLSVISLDPEDEIGLKTPTLIKMSTELTHGRNTAERIVMLYRVAAALDLSYVYVIHHPTPITLVSLVLRLNVGGVIQLARDLIHALPVPQSSIASFLCEEAVATITAGPSATQRDRLLLWEELETHWCEMITLCEDPSSLGNQLLLVGQRIGSSHPDQVEKVHSMSVELVIRAHDCFTAASNMEGISTVLRTALALTGSLLQHSQWSLMVRLLTGIGRYSEMSYVIDALREHDQFEPLLGRGSDPRGCKKGLDRALVHYLRSKYPEDTETLRLVALHFLLYSEVAEMWATDAEKAVEKVLEATVDLGVSCSTGMTSPPVRSTPNKNSTREMSTKNTPRKSTPMKGLSSPTGAGRSFPANDQFDPDYLHNADSKLLVQAMHSYAHAAQYYMQDQQLATAVEYSRQAELVALQTAHVRNATSGSALRLLKLSPGGVRCVTTRLLRVCEAQLVGRAYNLSVDWGAALYQQFINKGDENYLTEYLAHCTLSPEIVLDVIKKLEHDGVTKERQERVALLLKHVQEADVVYRVASQLGLRGTVDACLASSSAPYLRDTVFTKGFTYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TNR2</accession>
    <name>A0A423TNR2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative ras-related protein Rab</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003188</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001430">
        <property type="protein sequence ID" value="ROT78100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TNR2"/>
    <dbReference type="STRING" id="6689.A0A423TNR2"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT78100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="142" mass="16341" checksum="A7F0D1F9386A3EC7" modified="2019-05-08" version="1">MLLGMVHVRCKAPGSNRYYRGTHGVIVVYDVTNGESFANVKRWLHEIEQNCEVVNRILVGNKNDCPDRKVVLYEDAKRFADQMNIHLFETSAKDNINVEEMFTVMTKMVLQTKKEQKDRQSATSDPVRLHNPKKGKGKQKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TQL6</accession>
    <name>A0A423TQL6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Acid-sensing ion channel 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_002524</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001339">
        <property type="protein sequence ID" value="ROT78758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TQL6"/>
    <dbReference type="STRING" id="6689.A0A423TQL6"/>
    <dbReference type="OrthoDB" id="6381924at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015280">
        <property type="term" value="F:ligand-gated sodium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.470.10">
        <property type="entry name" value="Acid-sensing ion channels like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.770">
        <property type="entry name" value="YojJ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001873">
        <property type="entry name" value="ENaC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690">
        <property type="entry name" value="AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11690:SF300">
        <property type="entry name" value="PICKPOCKET PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00858">
        <property type="entry name" value="ASC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01078">
        <property type="entry name" value="AMINACHANNEL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 12" id="KW-0894">Sodium channel</keyword>
    <keyword evidence="10 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="608"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="80"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT78758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="648" mass="72904" checksum="21D9BBCFFB8E2F17" modified="2019-05-08" version="1">MADERETEEVGLPPEREARDSRDATRSFARNAGLCVQDRLAFDEDPPSYEMMYPSSSDDRNASILSNTNIDCGIVLSPTNLKENTKSQPNSNQIVPQTPQDTKVTSRPAIKHDDSKLKLTQENEKPEKVLQRKITLTKLTETREKLMVQASGLTKGARETLREFCQKTTAHGFSHVVEKDIHIIMRIFWVVVTFVSLGALLSVGYDATYAAFVTKRPYTEVTYRNNQSTGIRLPDVTVCTLSGFWKSKMEQYNVSKTLASYLLLAVRGTEVISPVLSRDPKRIILLREELREYLEVHKVTLEELIIMLSPGCEELVKGCYSASESMSSSECCQTVLRPTITTLGVCFTTLNQNGLRLNQTIAGLVGGYRILFDVALREYMEFDYNVVSTTSLAEAGIHVSLSNFASSPAVAANIQAVRIAPNTAASVALDVTNIDHTEVYLDAWLLPNPRPRCVSEEKFWAMSEEERAYTGSNQYFSLLYRDCLNYYFNCSFLPFMFANDTTSACMPEITLYQSKINDEMMDCVQNHLSQLGGDFGKLCFTTTINQQLSYTTLMESGVQSIIDNRLLPPNITLSMVNIYYTELGFTEYYERIPTFITWFSDLGGQMGLFMGASFITLVELIFTVCYVLRVLLTRGLRVLMNKVCGNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYN2</accession>
    <name>A0A423TYN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transcription factor SOX-4-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_025242</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000951">
        <property type="protein sequence ID" value="ROT81569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYN2"/>
    <dbReference type="STRING" id="6689.A0A423TYN2"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007420">
        <property type="term" value="P:brain development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22029">
        <property type="entry name" value="HMG-box_SoxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000002">
        <property type="entry name" value="transcription factor Sox-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF323">
        <property type="entry name" value="TRANSCRIPTION FACTOR SOX-14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="6">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT81569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="505" mass="55163" checksum="64A70F1598A57A87" modified="2019-05-08" version="1">MLVNDSSSTPYSDATQTKKHPPNHVKRPMNAFMVWSQLERRRIVSQTPDMHNAEISKQLGRRWKLLTEEQRRPYRDEAQRLKVLHRLEYPDYKYRPRKKNAKGCAPPLASLPGGAGDVLRGVALGGGGRVSKGRSPLVGGTHSPPANAATVIKMRECLRAANLKHLASKAAVPPSAAPQQQKPQPMSPSARLPTSPSHDLPDSPEGAATFKNRALRSADHAVKEERRGDPMYCSGGAPEAGFGWPSDLLLASSPSAPPVEAAPLAEDPPTLADLDNIGVKDLVPLSPGLALDLHALGSDIELWPAHEAGRDPSAPRDLATPPTPYHSGLQDPWTQALWEDDVESFVEELQIKYQPLQLEASPPTASQAGAASAWLRPALEVLSAPLLDRKSPNAAGFVSLPGDSAARRVTAPPARNDLKSRPDTLPSSPFLLFFQPLFLLFSSSTVQRFRHPDRRRPPGQRRKCSFLPFCWSKANPDICMLSICLLTVDVRRAWQLIWPGVLVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2Q3</accession>
    <name>A0A423U2Q3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative armadillo repeat-containing protein 10-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023816</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eutherian X-chromosome-specific Armcx family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000752">
        <property type="protein sequence ID" value="ROT83005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2Q3"/>
    <dbReference type="STRING" id="6689.A0A423U2Q3"/>
    <dbReference type="OrthoDB" id="10017790at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006911">
        <property type="entry name" value="ARM-rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051303">
        <property type="entry name" value="Armcx_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15712:SF23">
        <property type="entry name" value="ARMADILLO REPEAT CONTAINING 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15712">
        <property type="entry name" value="ARMADILLO REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04826">
        <property type="entry name" value="Arm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Armadillo repeat-containing" evidence="10">
        <location>
            <begin position="234"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="161"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="189"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="442"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="452" mass="50058" checksum="ECBC5E126D361F2A" modified="2019-05-08" version="1">MSSAAGGSLQDRTLNKVALCSAVFAGFAYVGYSYAKTAFCRKLAKKPGALEDEDTEVSRVVFRRLSQTTQTDVLLGNLDMSGTSGKIIIRPKTVQERIRELNLKARQFADTFIAIQTGNGHAGHAVSRNSAIHDPKSLQSSPWNSPRLLSPVDVRHLITSRSTENLTHIPPDGSPSRPKWRRKSLRKKKAEESSDPDGKLRKKRVEAEALQLYKNTRDELTQRLEHLSSRGRVLTPYEAKSLVALLYSEDKTLIERALVTIANCAAFSVNLDFLREVGCIHRLTTLLEDNEVRLPAVQTLGNVVLSEENIRQAKDCLPILMGFVQNSHGDDALRLASLVVLTNIATISEWHEDYCPLLHRLYHLVDSPNPHIQLQSLRLLVNLSCNREMIPSLLAAEGPRKLSSLVVPETNEAILLRVLTLLATLAHAVSEDNLNPSVDLPPEDKAAAPDTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3C3</accession>
    <name>A0A423U3C3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chitin binding Peritrophin-A domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023614</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000718">
        <property type="protein sequence ID" value="ROT83209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3C3"/>
    <dbReference type="SMR" id="A0A423U3C3"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019439590" evidence="8">
        <location>
            <begin position="21"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="9">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="10">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="9">
        <location>
            <begin position="288"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="9">
        <location>
            <begin position="351"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="140"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="43530" checksum="4B3281B3D066BAD9" modified="2019-05-08" version="1">MAGVKCLLVLAALALASVSARPSTECSCDGCLYPSLSDCSVYWKCQGGRAVEHRCGGGHRFNPDTSRCEHAIRVACSNTVRLVGDFASETCVDRRAGCPVFAAAGGCECRGDDCDWPAYVVSSCPKSCDMCGAQSKFKPWWTDSSEEDSSEEGGRKPWWKDSSEEDSSEESGEGGSSESSESSSSESNESSSSEESGEDEGNGSGEGNGSGEGKAPAKETAMGKTAPPPPPPTAAPTTRPPPHPQQPSLLPLPQQPQRRSLLPLPQQPNDPPPTAAPTEEPSKPGNCGVDCSQGQYHPHPSDCHMFIQCTPYGPQEMPCAPGTVWDQDLLTCNHEATTPCVIADPCVKSHDKQCRRGDGRYAVEGKKTEYYLCHSGVSFLLRCPDEGTFNPHTTSCVYKDRTAIGKVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U575</accession>
    <name>A0A423U575_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Crustacyanin subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U575"/>
    <dbReference type="STRING" id="6689.A0A423U575"/>
    <dbReference type="OrthoDB" id="6339451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031409">
        <property type="term" value="F:pigment binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003057">
        <property type="entry name" value="Invtbrt_color"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00061">
        <property type="entry name" value="Lipocalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01273">
        <property type="entry name" value="INVTBRTCOLOR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00179">
        <property type="entry name" value="LIPOCALIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018825289" evidence="3">
        <location>
            <begin position="17"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="5">
        <location>
            <begin position="48"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="191" mass="21512" checksum="8D755AE666C363F8" modified="2019-05-08" version="1">MKSAVFFVAFVAAVAADKIPDFLVPGKCPAVNEKALFEQQIPNHSKYAGVWYEIALTNNPYQLLKQCVRNEYSFDGSKFIAKSTGINADGNLMRHNGQVLPMPLGDPHLSIDYEGSFTAPYVILDTDYENFSCIYSCVEFNYGYYADFAFIFSRSPSLSDQYLRRCEAAFKEIGVDVSRFREDSPGFELPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U923</accession>
    <name>A0A423U923_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PMS1, postmeiotic segregation increased 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000391">
        <property type="protein sequence ID" value="ROT85208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U923"/>
    <dbReference type="STRING" id="6689.A0A423U923"/>
    <dbReference type="OrthoDB" id="10254304at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03484">
        <property type="entry name" value="MutL_Trans_hPMS_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000032">
        <property type="entry name" value="mismatch repair endonuclease PMS2 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="2">
        <location>
            <begin position="12"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="219" mass="24404" checksum="217100C72641AECD" modified="2019-05-08" version="1" fragment="single">MEFKQETASDDILSEYGMQCSSEDIKGNTLFTLEGFISSCEHGQGRSASDRQFYFINSRPCDPAKVIKVVNEVYHQYNRYQYPCVVLNIRLKEDDVDINVTPDKRQILVNNEKLLLATIKTSMIRLYGNIPNSFKMQNTSLNNSFTSSQSNNTPSRASPSVGSPSNSRISALSQKFGRKSEGSPLSNLSPTQPSTPLSVFSLKRSFSNSSCTDESQVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9T7</accession>
    <name>A0A423U9T7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL38</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L38</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000280">
        <property type="protein sequence ID" value="ROT85429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9T7"/>
    <dbReference type="STRING" id="6689.A0A423U9T7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="70" mass="8396" checksum="EF52F5B50B4F35A1" modified="2019-05-08" version="1">MPRQIMEIKDFLLTARRKDARSVRIKKNKHNVKFKVRCSRFLYTLVIRDREKAEKLKQSLPPGLQVKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAA8</accession>
    <name>A0A423UAA8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000224">
        <property type="protein sequence ID" value="ROT85644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UAA8"/>
    <dbReference type="OrthoDB" id="5987729at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001517">
        <property type="term" value="F:N-acetylglucosamine 6-O-sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051135">
        <property type="entry name" value="Gal/GlcNAc/GalNAc_ST"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704">
        <property type="entry name" value="CARBOHYDRATE SULFOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10704:SF44">
        <property type="entry name" value="LD35051P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="363" mass="42116" checksum="1DEFD3A8D04849F5" modified="2019-05-08" version="1">MLAAPRPRVVHNVIVIVFFLLFYFCLRIAVLGGQEEEASLLRNDEAFRYRIEKKVPLDSYADARDDTKPPPSPPLWILTLSSLPRSGSTLMAQFLGTLTNSIVFFEPMWIKEYTPCAEDEDCVVDYIYNIFNCTYKQDFEDWFRKKDLFFSYFHPDVRNCKGAGCKDALDVRGMCERADVRVMKIIRTRLAFLEPLMSDSEINFKVVFLTRDPRGSLNSIRKFGWNRDPMTRCTHLDKDQVAYEELSGLYPDKVMQVKLEDFCLDPIGTTEDLMQFLYGHSDIPEPLKEYLTKHMTTKTQKGTMSTYKNSSQEFEAWRYKIREDDLLKIETEPVCVRTIESMGHALFGSIQKANDSSVPLFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBJ1</accession>
    <name>A0A423UBJ1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_011829</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000025">
        <property type="protein sequence ID" value="ROT86057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBJ1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT86057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="112" mass="12605" checksum="4C4508A6D1A458F2" modified="2019-05-08" version="1">MPQSAEVIRKKIKAELNLQLLNCPIISGKWARRGTKTRAKAQRHGHLAGSVSEASLRSGGVRSGSWRARLVVRSVRVFPPTRLFPASFFVRVTDRRLRGIMRQPVECVPRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTG4</accession>
    <name>A0A3R7LTG4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003350">
        <property type="protein sequence ID" value="ROT63943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTG4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="920"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="920"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="967" mass="97593" checksum="8F7F5D8AD52A7DE4" modified="2019-04-10" version="1">MSLRSLSLSPILQGRREREGERHPPLGKRERGWHCFHDVTPGEAVGCGAAGGEAGCRAGLGARAAGAERRPWPAVWRRRRRRVSHSVRSPVPPPGLSGRAACPARPFSLEGWRGDCGPGGCGGGGASWVLGWPASHILLGWPGDGLGFSLPLRPPAPSRAEGGGPWPGLACLVFLRTGVGSGFPPSAPGALSGRGRRRGIRAWPCRTPDGASPRPDGQGRALGAVVVAEGLRRQRQGDCLGCGRRGATPASSPLLRPPSGPARPPAPAVQGPPIPGLAAWLSCPCALSGRGRRRRARAWPPRREEAPASPAPVLESGAGFGGSWLPGPSEGLPSVAPGAEPCPRSCGLRARADNYRGKPPSAAAGWRGRASSPSGPVGGLARAVRGHPAGWASPPGRAAWALLPPAPSRGRRRRRRGRGPRRREEAPASPAPVPKAGQALGGPGCRGRRRGCLPWPPGPSPARGRGGGGGRGRAPRRRDEAPASPAPVPESGAGFGGSWLPGPSEGCLPWPPGPSPARGRRGRLWGVLAAGAVGGAAFRGPRGRALPAVVGAGFGGSWLPGPSEGLPSVAPGAEPCPRSSPASPAPVPESGAGFGGSWLPGPSEGLPSVAPGAEPCPRSCGLRARADNYRGEPPSAAAGWRAGGKLAVGAGRGLARALRGHPAGSPCLSGSRPESGAGFGGPGCRGRRRGCLPWPPGRALPAVVRRRGRAPRRREKPPSPAPVPESGAGFGGSWLPGPSEGCLPWPRGRALPAVVGAGFGGSWLPGPSEGCLPWPPGRALPAEAPASPAPVPKAGQALGVLAAGAVGGAAFRGPRAEPCPRSCGLRARADNYRGNHLRRLRAGGGRASSPSGPVGGLARACGGILLPLPLRLPSRKRGRLWGVLAAGAVGGAAFRGPRGRALPAVVRLGLSCPLRPLGPPGAAGASPRAPPVSAVPAIHTGSLDVQPRGLPSLAPGAERPLPRGRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTN0</accession>
    <name>A0A3R7LTN0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003621">
        <property type="protein sequence ID" value="ROT62576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTN0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="562" mass="62690" checksum="A804419A6EE7476E" modified="2019-04-10" version="1">MNPKEPLESLGTPERSSSPEQTRLDTPSPMQGNIDLQALSFISEGSEVLSTPIQPRDADQPPVGVDEMGVNGMGGTSPMSDTEIGPTIEEPPNLTPSLELAQRTPQPQENEPPQVDERNILDISLPFDASLDTAPTPAQEDRIGACHELIDRVVERPTYPLPPRPLRSPPGSEKTSLGQGNKKNTKLGRSGQWEKVQESICRSRNPRERKQGEKDVQRKVCEQEQIQGRTETRGSPKIWAGFGIWESPGVLRTEQGEGSSKSRNKRKLPKGSRSKRRKTVAKRREWAAGLETIVSEEELERVQEESKLLVSRFYCLDSPTGKRSSFTAAQRDALLAHKPSIPHWETSTQWLLCTYKTGRPLTNDLSLSFIRTPSRKAAGYDPFSEEAEDSTQTSGRKFPIFLRYSIPLPFYPTGRSSLGTLLKFDNKCYQQMKGTAIGASVSVAVAEIFVHAKKIAGPLRESINRIWDWVQEKAKDTPWEDRMTGPPPMIAWKKDRTIREDPQKPANPQENGGGRRKTRFSHRMSSTQTAPLLPPPSLPAVPSFGNTRDIHRMSLHHLPPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUN2</accession>
    <name>A0A3R7LUN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RAS-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_017233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003179">
        <property type="protein sequence ID" value="ROT64825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUN2"/>
    <dbReference type="STRING" id="6689.A0A3R7LUN2"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004198">
        <property type="entry name" value="Secretion related GTPase SrgD (AFU_orthologue AFUA_1G07680)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT64825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="20829" checksum="944E93A1EFB6D9F5" modified="2019-04-10" version="1">MKMPTLESNHTIGVEFGSKIVNVGGKSVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDLTSRDSYNALGNWLGDARTLASPNIMILCVGNKKDLEEERQVTFMEASRFAQENELMFMEASALTGENVEEAFLKCAKSILAKIETGELDPERIGSGIQYGDATLRRLNRANSQRSKAGAECMGSSCRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LW11</accession>
    <name>A0A3R7LW11_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">LAT-2, isoform b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_021645</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004573">
        <property type="protein sequence ID" value="ROT60764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LW11"/>
    <dbReference type="OrthoDB" id="6350332at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053231">
        <property type="entry name" value="GPCR_LN-TM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902:SF4">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45902">
        <property type="entry name" value="LATROPHILIN RECEPTOR-LIKE PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="980"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1014"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1044"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1085"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1125"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1173"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1201"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="7">
        <location>
            <begin position="338"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="8">
        <location>
            <begin position="978"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="624"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="641"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT60764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1271" mass="140006" checksum="F1A96BEDFB4B0A4A" modified="2019-04-10" version="1" fragment="single">MQATGSIAFGAVALRGSLGNRYAIALVCEYQSLSLNCGGSTLDAKVVGCNVTEQSCRIQNQVVFRRPYGLKAEVVGEGVVQLTWTTEKAGWVTPTSSLEITDPEGNLVDQKTLSNKNNSVSVTGVSGGNNYTVTFIPEADSDNLPRFYFSLHIIAWRDVTTSERLEGYGAFVTDVDLSATIIWNGTLRPTDTTQTVNMSTTTSPMASTTTTAAPTTTTPVPSTTTTTPTSTTAIRPDTVAPSLSVQHNTAKAFMYTVTLSSDKGEVEQNVSMTTSPSMRLDFWYMSMEKQYSIALTCHFGGVSVPCGSHVLYVDKPLQWSNVNDRFVVYAEGRGLGGWEHQEKECRKGEGTLVSLATYEEDERLLTALVAKGTPPHLDVYWLGLNMCPDYDGDVWSDGSLWQHSRLPNVRPMLSSETCCIKAVWRPERQIYNWLGEDCQALFPTVCEFHPQGLVGRVVDLRRSDASTTEAAATWKYQANYWTPNLFVIRTCVVMDLEDLGTAERKATSDCITGNVTINATRFTQENLEPYKEYQVNVSASLTSIGYTGPSAAAFVRTHPETPVMVQVLPSGHLRVAEFAEDDNVVMKVTDGDGAEKQQTIQARGVLLDGLKLGATYSVSLEELGGKRRKEAASVQAYPREPTIPPFPLPADPPPPVNSHFTLPLRPADPHPHSPLPLSRPADTTPPPPPPVNPHSPSLRPQTPRNPHSPPPLPVCPARRPPPSPHPPCECGDECHLRGWCFEPSPAKVNSITAIRECQDEETSLATVSSSEQVDLLLKLADKVGDDLWVSERSERLSASRDTLRLLAEGDSEILDDETAAEESTTAIPMPSQCLVVSRAERAVVDEPCANIHTAACGRKVPVAKAFPPTSSMKIDVGASWISLDWSNTDWVWKATYTVYYQRTRERRYKRALKSMDFKAPPVLISNLQRDTSYTLELVADLDNGFLSSSNEFEASTSNSTDRAYPDRLKVGWAPSWDYQILQLVSAAILVASCITTMLLFFATGMFYQDCVAQLGFLATLMAAYFNLMLAHPSTVNADNETGCMIVAIILHFLFTCSFMFLMFEALTIAHLLVVQIKSPFQNSNWLMMIVGVLVPVLIVCISAAIEYSKYPDFTKHNCWLNPESSAMWAEAIPIVVLLIATLFLLLNTLRSQETPPALIEVDLRGRQSDSHKLRWVILALAVELFVVWITGVTAYQYHDSSLHVVFGIFTLILAFTIVACRTTFDDTFRTKMHRLCCGTELTYKRSEILTLSGRSRVGPSPVQMMNTSATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LWT5</accession>
    <name>A0A3R7LWT5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Venom dipeptidyl peptidase 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_015406</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S9B family. DPPIV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LWT5"/>
    <dbReference type="STRING" id="6689.A0A3R7LWT5"/>
    <dbReference type="OrthoDB" id="16520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000003">
        <property type="entry name" value="Dipeptidyl peptidase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.30">
        <property type="entry name" value="Dipeptidylpeptidase IV, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050278">
        <property type="entry name" value="Serine_Prot_S9B/DPPIV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731:SF200">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 10, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731">
        <property type="entry name" value="PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Dipeptidylpeptidase IV N-terminal" evidence="17">
        <location>
            <begin position="161"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="16">
        <location>
            <begin position="634"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT66607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="838" mass="94056" checksum="9C3AD1646C52486D" modified="2019-04-10" version="1">MIRHLGAQRPRGHGRRRRDGRTYPCGGGGFLTLPPLTSPPARELVGLARPRVWRNLLLGTVGVMLIVAAAIGIVIATRRNGSPIPLTSALTATPGGIDLAEVLNGTFSANSFNGTWISDNEFLFRSENGALKMFTVETQSTEELVSQEIMAEWRPFKYSLSPSRKFLLVVHDVQKLFRYSYLARHTILNLETGESIPLAPQRVRSRNDQPPLLYATWAPTDDALAFVSHNDLYYTTGPDLATMYRLTDTGQIGSIFNGIPDWVYEEEILSSNSALWFGPNGLRLAFATFNDSRVDTMNFPLYGRPGDLSFQYPIQQSIKYPKPGRFNPVVDLWVVDLAKLISGSSDTVTRLPPPATLSNVDHYFTTVGWASPDFVSVNWMNRHQNVNILSICQAESGVCSDDLVHESPDKAWNDLYTPPMFDEANGDTYLIILPTFQGDRGHFKHINFRRSSDKTLTPLTTGTYEVVDILSWDRKNHIVYFTAAPSGRPGQRHIYYVGDLSSPQPKQAYCITCGFKNDFNEDCNYNSAEMSKDGTYYVLTCGGPGIPQVTLHRASDHSRLRLIEDNQEVRERLLDRSLPLEKRLEIDVAGGFKAQVSMKLPPDYNPTRFQSYPMLVYVYGGPGSQLVSDRFRIDWGDYLASERGIIYASIDGRGSGYSGDKLLHSLYYGLGTAEVDDQIAVTSALQKSFPFIDSSRTAIWGWSYGGYVTAAALSKDVNNVFKCGISVAPVTSWIYYDTVYTERYMGLPTPDDNLRAYDASDITRNVTNFRNKEFFLIHGTADDNVHYQQSMMLSRALEVNDILFRSQSYPDENHGLAGVKRHHYHSMEDFLNDCFNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZU8</accession>
    <name>A0A3R7LZU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminopeptidase N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZU8"/>
    <dbReference type="OrthoDB" id="510539at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF299">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="2">
        <location>
            <begin position="111"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="202" mass="22700" checksum="B1BD3CEFF47BFBDD" modified="2019-04-10" version="1">MQSNSYAYSDKIPGWVWARLHHVHLPSPLLLLPFPRPPLPLSSSPSPSLFGPPLPLFSSRLPSPLLLSSSLLPFLSPSLSLSFSRPSFPLLLFVMDLLAPAESHWSCDMASQDSMAELTLFACRLGRHESLRLFRRWMRHPENRTSLSPNHWSEVLCTGVSAGGEKEWELVWNEYLNSNTTQERTSFLTALACSENATILSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZY7</accession>
    <name>A0A3R7LZY7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribosomal protein S6 kinase</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_014042</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01002747">
        <property type="protein sequence ID" value="ROT67855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZY7"/>
    <dbReference type="STRING" id="6689.A0A3R7LZY7"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05584">
        <property type="entry name" value="STKc_p70S6K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000092">
        <property type="entry name" value="Ribosomal protein S6 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000686">
        <property type="entry name" value="Ribosomal protein S6 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016238">
        <property type="entry name" value="Ribosomal_S6_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000605">
        <property type="entry name" value="Ribsml_S6_kin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="71"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="17">
        <location>
            <begin position="334"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="77"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 13">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000605-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000605-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT67855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="54147" checksum="D148FE7E13095C27" modified="2019-04-10" version="1">MAAPGVFDLELQEEDAIECDQSDDDAIEVEESQYEQGPDINAILQSEGIETLQLSDSTVNPGMEKARPSDFQLLKVLGKGGYGKVFQVRRVSGGKGAGKIFAMKVLKKATIVRNQKDTAHTKAERNILEAVKHPFIVDLVYAFQTGGKLYLILEYLSGGELFMHLEREGIFMEDTACFYLSEIILALEHLHSEGIIYRDLKPENILLDSYGHVKLTDFGLCKEKIQDDSVTHTFCGTIEYMAPEILTRTGHGKAVDWWSLGALMYDMLTGAPPFTAENRKKTIEKILKGKLNLPPYLTPDARDLIRKLLKRQVSQRLGSGPDDGEPIKRHLYFKHINWDDVINRKLDPPFKPVLTGDDDVSQFDSKFTKQTPVDSPDDNMLSESANMVFEGFTYVAPSVLEEMARPSVVKARSPRKPYTPNSGGPFSPRLGGMQNPFTFANGADTSSSSSGQEMIVFGSFLHAALLPSPPLSSPMTFCPPSFLPSLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M057</accession>
    <name>A0A3R7M057_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_018393</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003394">
        <property type="protein sequence ID" value="ROT63713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M057"/>
    <dbReference type="STRING" id="6689.A0A3R7M057"/>
    <dbReference type="OrthoDB" id="423283at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019871">
        <property type="term" value="F:sodium channel inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048814">
        <property type="term" value="P:regulation of dendrite morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000017">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase NEDD4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF440">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE NEDD-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="WW" evidence="11">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="12">
        <location>
            <begin position="113"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT63713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="332" mass="39088" checksum="725F6AABA24B0FF6" modified="2019-04-10" version="1">MPSSPPNQRHANNWRHEDELGPLPEGWEQRVHTDGRIFFIDHKNRTTTWEDPRLLNPAIAGKAIPYSRDYKQKYEFFKNNLPKPANVPNKFDIKVKRNNILEDAFAIISQVTRVDLLRTKLWIEFEGEVGLDYGGVAREFFFLLSKEMFNPYYGLFEYSATDNYTLQINPYSGMCNEEHLRYFKFIGRVAGMAVYHGKLLDAFFIRPFYKMMLGKPIELKDMESVDSEYYNSLLWIQENDPADLDLTFSVDEESFGRTSSHNLKENGGEIPVTNENKHEYIGLVIKWRFVQRVHDQMEAFREGFSDVVPISHIKIFDEVYYSWICFISIFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M085</accession>
    <name>A0A3R7M085_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inactive hydroxysteroid dehydrogenase-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012431</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002568">
        <property type="protein sequence ID" value="ROT69377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M085"/>
    <dbReference type="STRING" id="6689.A0A3R7M085"/>
    <dbReference type="OrthoDB" id="5545019at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF40">
        <property type="entry name" value="INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27360" checksum="27130162A8332BCA" modified="2019-04-10" version="1">MRGDGGMQDATLHDRLARRGNMMDLEGFQLFPYPNAFLNGIVLVGLLSVLKFFTVTTWNLAVGLRAHVWSKLRNKNFVETYGRWAVVTGSSDGIGKGYAYELAKKGMNLLLISRTMEKLQKIKEEIEKEFGVEVEIMQVDFSHGKQCTRDRGTRERKGVNNVAVIVPHPMNFGEVSEHQLWSHVNVNVASPLAMTRMILPGMLERDKGAIVNIASIYGRYPVPMVQVYSATKVSTGWERRWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4L3</accession>
    <name>A0A3R7M4L3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hemocyanin subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_014892</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002862">
        <property type="protein sequence ID" value="ROT67046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4L3"/>
    <dbReference type="STRING" id="6689.A0A3R7M4L3"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF5">
        <property type="entry name" value="FAT-BODY PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00209">
        <property type="entry name" value="HEMOCYANIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemocyanin middle" evidence="2">
        <location>
            <begin position="183"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Hemocyanin C-terminal" evidence="3">
        <location>
            <begin position="454"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT67046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="709" mass="79374" checksum="F25A03C9FAD63597" modified="2019-04-10" version="1">MDTIELLLPSPPSPPSSPTSLPPSPPPLLPLLFPSPSPPSSPTSLPPPPPPSSPTSLPLPPPPSPVPSPFPSPLLLSISLPPPSPPSFLSYFPSPSPPPSFLSYFPFPLPPPPRCIARSRNTIITSTTILETLSEANDHPELADIALTVRDHVNEALYIFALYSAVYEMEVASPPDIPSLETVLPDRFINNEVVNEARRLVKAADVVHVRWYHNQTGLSTRNTENRVAYWREDLFLNTFHWHWHLSNPYLSKPGKIDRRGELFYYAHHNMVARFNMERLSVGLKPVETFEDWRLPLENGYFPHLTAGNGFIWGDRQDDTLMQDIIGINISDAIYISKLELHRSHLLYSIDERYLICENGSQIYLTDDPAPGTPYGINLIGEALEAGASVNPAYYGNIHNNGHMLFGGSNDPLKKHGGNVGVMSAMEISARDSVFYRWHKFVDDVFFRYKMTQPPYTPDQLSVDVEVMEVAVQEDNGTLNDLHTFFTENTIVASHGMDFHLDPESNITVLYTSDFLNHTDFTYNITVNNTKSGTMKPKVRIFLAPKYDENGLPLTYASLLQYWSEMDVFEADPIDPGVSTITRRSSDSSILSAYTGNNANFSFSGCSFPRHLLLPRGKPDGMTFRLFVMVTDADQDRAFGGGEDDPPSFCTFCGIPGAPYPDRWPMGYPLERKSLHTEIDDFVDAYSNMMVIDVNIYHQEEPQGEENPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4M1</accession>
    <name>A0A3R7M4M1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002856">
        <property type="protein sequence ID" value="ROT67061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4M1"/>
    <dbReference type="STRING" id="6689.A0A3R7M4M1"/>
    <dbReference type="OrthoDB" id="10037824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056707">
        <property type="entry name" value="DUF7805"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053207">
        <property type="entry name" value="Non-NMDA_GluR_Accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537:SF3">
        <property type="entry name" value="CUB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47537">
        <property type="entry name" value="CUBILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25090">
        <property type="entry name" value="DUF7805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="878"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="210"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="4">
        <location>
            <begin position="372"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="372"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="938" mass="104637" checksum="81E76C1408BE41DB" modified="2019-04-10" version="1">MKTTAEEGRSRFSESLRNPRLLVRNGNFLRLRSFLLAHLRTFGSSFSFNLYPPLPPIILFCYISLFPHSFPSRTSVLHTYIPFNPPFPHSPAPFLLSFPLSTQPFLAPLATFYSGVGGCEGDHVSIEEPELAERGGRWCGEGSGLNVYYSETDTVSVTLQAASTTQGEYFDNPLKFKIRYKFLPREQAVVRYGRGGVAKYRGEGVRNTVCSRVFQGCRARQCRLQSPNFPGLYPRNVTCYYLVKALPPPASGFTPVITLRQDNDRLVQVGRQGPVGRVSPESRLLQDNECRGPEDFLLVYDGGSMKAPLLAKLCGTATVPNITSSGPEVLVVFQTATSGRMNHLPNLVTGFELEAHVLYINQEASNINGLQCKQTIKSFGGTNGIVASPVFAVPPNASCSYQFEGRRGEVVWIYFTKYHKARKKQGMMGHHPCRNRLAIFDGKPFTGTPPDASELMANYCDEQLPPICVRSRQKGTVSQPCTLKESFLSTGTNLAVTQDFTDGTSLLPLDYSIYYEFVTVSLEGIEPGTDCDIEFSSSRARSGHFNSPKNVFLYGRGGKSSLSCKYTFKTEKGEAIKLRLTSVGFRGNMCKTVYNFQTNLYDCIARLPGSATLEVWEEPWRQTRLPLGCVCDGGLAPASFVSHTRLLQLDFTIKEMSWSQDFNDFYFDAEYEFIKTKGCDEQKILNGSTGSILIGDKKELEESGEEGSNEKCNDYPWRINARDNSHLYLNIPGYHASSQRCSTRNRVVVFGSHTARPLRSACPEPNVADSVDIFSSGWTTQLDMLEPLPESLIVRYLGREPGVYKLTWLEVRREPRPSALESLKGGAGRRHITGATCGHQCPELDACISPELWCDGVKHCPSGADELRSTCLYFTIPWLYLILGAVGVLLALLVFASALVAVRVYQRGKVKRKKKKEAQRLMTREVILPMNFHKENIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6Z1</accession>
    <name>A0A3R7M6Z1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002630">
        <property type="protein sequence ID" value="ROT68822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6Z1"/>
    <dbReference type="OrthoDB" id="239701at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="104" mass="11426" checksum="8DD24D1A93DE4154" modified="2019-04-10" version="1">MILRRGGCVDLRSSVVPSRPSGRGLDTRDTESSRQMQHGRSEPTRFRYGGVGFEDQLRGSDDSIGTLPNDLDHGYVAVGPDSMQGSSALSASRDREWRALMEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M945</accession>
    <name>A0A3R7M945_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_006098</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001781">
        <property type="protein sequence ID" value="ROT75367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M945"/>
    <dbReference type="STRING" id="6689.A0A3R7M945"/>
    <dbReference type="OrthoDB" id="643377at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000082">
        <property type="entry name" value="Leucine-rich repeat-containing 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000483">
        <property type="entry name" value="Cys-rich_flank_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050541">
        <property type="entry name" value="LRR_TM_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369">
        <property type="entry name" value="ANTIGEN BSP, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24369:SF211">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 15-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00082">
        <property type="entry name" value="LRRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018566960" description="Ig-like domain-containing protein" evidence="11">
        <location>
            <begin position="36"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="12">
        <location>
            <begin position="275"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="475"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="597"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="854"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="869"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="893"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT75367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="942" mass="103937" checksum="C26862F2AD6DE2EF" modified="2019-04-10" version="1">MSKPQGSRSPLYQPRTRAVLAWACMWAWVVLEVSAECPKVCECKYRGGKELVVCRNAHFIDIPRGLPPSTQVLDLRHNNLKILPRDAFVYSGLVNLHKVWLNYCKLMWLEDGAFRKVANVLELDLSNNKLRSVPSGALKDLGRLRELRIADNDLSTIADSAFKYSLSLVQLDLSQNRIATIEPGAIMILKNLEVLNIADNKLIALDGNELRPLSLLSVIRLEGNPWHCDCHLRSLRQWFYDRSMAASVPPSCSKPRWLMGRDWQLLENEEFICVPKVTAVAPRVLAAYGENVSLLCNVETEVETTIFWLFGDSPVYNASEVEQYEVSELLAPNNTTYISNFTITDIAPEDQGVYRCVAENRAGRGETNFTVQVSHEVAEVRVANIEETSYMTEGLLGGIATSVSVLLLACSLLYCKFRSARVREPEPKVEESPEPQSSTCDAQHKFAGYHIIPSCDSEEAQAPRDAEVQQAWACREVSSSDSSRPTEVSIEPGLMQDPSPQGPSALAMPPSSVSFVQIPKMEAAYTLNLPEERGRWKNFTCGNRMCGRSVSQASLRDSEQYPDLLDLPHSQLTQLQNQPQQLHAIQTQDGVELQTTNPAFCTRPRTRSDAVCRSASVRQTSSTQASPQNTQQDPSDYSEAASNAYAHAHAHLPMSSHQCLPTPPMLESHDQRALRQLVASQRTDCTPAGGACKHADTADPYHFEYHAAQLEKFLQEYRCLQAQLLHMKQSYEAHKRAGSMPRLDCCSQVGEGAQASPVPALPKEVCCACTAHSPFVGHPPEGAEKAPQAASVVPGYPGGQQLSSPCGFAAESDVPQAVPCGYAGPSGMPAVCPAGYADSPTLPAVRKATVAFADPPCPRASTRARWACPRRSTAPRTRSTQSLPPRTPAARPPPRRSPRLARARSRTPTRPPRRRPPRGSPLRPQSQARRRRRRPPSPTRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M985</accession>
    <name>A0A3R7M985_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fork head domain transcription factor slp2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_004961</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001660">
        <property type="protein sequence ID" value="ROT76455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M985"/>
    <dbReference type="STRING" id="6689.A0A3R7M985"/>
    <dbReference type="OrthoDB" id="6230630at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990837">
        <property type="term" value="F:sequence-specific double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20021">
        <property type="entry name" value="FH_FOXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000135">
        <property type="entry name" value="forkhead box protein G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047208">
        <property type="entry name" value="FOXG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46617">
        <property type="entry name" value="FORKHEAD BOX PROTEIN G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46617:SF3">
        <property type="entry name" value="FORKHEAD BOX PROTEIN G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="4">
        <location>
            <begin position="36"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="2">
        <location>
            <begin position="36"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="353" mass="37519" checksum="BD1D55B108F79AB6" modified="2019-04-10" version="1">MSDSEVEDQSEKDEKDSKKGAGEDKKEGDEKKKHEKPPFSYNALIMMAIRSSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSADDVFIGGTTGKLRRRSTTASRNRLAAFKQSLLGRFGCYPPFGLAPYARGGGAALAPGSLPAALPGALASAPLYQQAAAAAALYRGYPPVDRLLADTPISAAPTSPVSSVGAPPPLLLGGLGGSTTMTPYEMYRTSLLSHAGLSHALGGMTTALSPPGGLGVMGLSMGGAGTSLLPARASSAPPPSPRPWACGRTGEAALCSHERGSQAMGSLPHDKVAPSTVHQMLSQANPHVRCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAQ2</accession>
    <name>A0A3R7MAQ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001616">
        <property type="protein sequence ID" value="ROT76727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAQ2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="331"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="40674" checksum="E1DC81739EF42ACE" modified="2019-04-10" version="1">MNHSLSSSFPLPLPLFFSPPTLSSSPPPTPLPRPPLPTLPRPPLPSLLGPPIHSSRPPLPTLPRPPLPSLLGPPYPLFLGPPTHSSSAPLPTLPPPPLIHSSSAPLTPLLSPLPTLPRPPLPSLARPPYPLFLGPPYPHFLGPPYPLFLAPPTHSSSAPPTHTSSAPYHSSSAPPYPLFLAPLPTLPRPPYPLFLGPPYPHFLGPPTHSSSAPPTLSSSPPYPLFFLGPPYPLFLGPPPTHSSLPPLPIPRPPHPFLGPPTHSSSAPLPTHLAPPLSTLPRPPTHSSSAPPPTLPRPPLPTLPRPPLPTLPRPPYSLFLVPPTHSSSPLLPTLPRPPLPTLPRPPPLSSAPLPTLPRPPPTFLGPPPPITSPTLPLPFVPLLSSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAX0</accession>
    <name>A0A3R7MAX0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001479">
        <property type="protein sequence ID" value="ROT77778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAX0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="49588" checksum="CBE217592DCB75F7" modified="2019-04-10" version="1">MRRLRRKANRWGVEVLSLPLSFSSSFFSSYSPSSSSFSSRPSTSLSPPSPLPPPLPPHLLPPPHHSPPRPPHCPPSLLHPPSPFPPLPSPTLPLPSSTPSPPPPLSSTPPPHSPSSPSPLPPSPSPSPPPSSTPPTLLPPSPHSLPPSPPTPLHPLFHHSPPPPPPSSHPLPFAPLHSPSFPVYGCQRAPVHVWSNLAPSLPCLLSCPPFAPSIYLLSCRPCSFFIFSLSPCPPTYFLSCPPWLPLYLVSRPPVILLIFSLALLCSLFIFSLVLPCSLLSSLFAFLFAFSLPSLFLVVPPSVLQELSASSYLCSALVGMCTSYPNLFLLWGHHSFYIFFSHSLYPTSSLHFPTHHPLTPCPPSLPPILYPHAPTHRHHSPTHHPHPYPPSLPVPTTPQPPTHQSLPTYLYHYPLPTLALPTPSLPPTPSHLTHSLPYATPCPHLTPYLPPSLPYPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MBA7</accession>
    <name>A0A3R7MBA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002214">
        <property type="protein sequence ID" value="ROT72029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MBA7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="43800" checksum="9F16410762A7F9A8" modified="2019-04-10" version="1">MRGKKRPLSEDYTQGGGPLSEDNSPAELALPKLFCHLRLLCSSLGDSSSPPPRLFSPHFFLSHHFICSPRYPHFFLSHFFLYRHFFRLTSLPSLLSLPSLLSFSLHLLPSLLSLPSFLSSHFPQLTSFSTLISFDSLLSLPSLPSLPSRLSLPSLPFLLTSLPPLPSLSPHPGLTLGLPSPPLPSPFPLPPLFPLPFFLSSPSPPFPLSPLPFPLLFLLPSLSLPSSSFLSPPLPSLLPSLSSPLPPFLSLPLSLPLSLPLLSLSFPSPSSPFFSLSSSFPLSPLSLPSPLLSLPSLSLPSSSLPSPSPLSSPPYPPPTRPFNSIFISLTPHPTPSSTPVISPSPPPFPPLPHFLSPPPSPSLPPSSLLSPPTLILPLSPTPILPPPPQSLPLNHLFGRENELVTSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDZ9</accession>
    <name>A0A3R7MDZ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Thrombospondin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_001970</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001260">
        <property type="protein sequence ID" value="ROT79303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDZ9"/>
    <dbReference type="OrthoDB" id="6357843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1080.10:FF:000001">
        <property type="entry name" value="Thrombospondin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017897">
        <property type="entry name" value="Thrombospondin_3_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008859">
        <property type="entry name" value="Thrombospondin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199">
        <property type="entry name" value="THROMBOSPONDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10199:SF100">
        <property type="entry name" value="THROMBOSPONDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05735">
        <property type="entry name" value="TSP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="TSP type-3 repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51234">
        <property type="entry name" value="TSP3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51236">
        <property type="entry name" value="TSP_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1 7" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="8">
        <location>
            <begin position="178"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="8">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="TSP type-3" evidence="8">
        <location>
            <begin position="252"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="TSP C-terminal" evidence="11">
        <location>
            <begin position="291"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="190"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="190"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT79303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="544" mass="59352" checksum="88275041D9D4018E" modified="2019-04-10" version="1">MQHYFECFMESGKMVKQRYQCPSGYMWSEESFGTGKCVEATDEYLGYPFAHCDIPDDLCPETDPCLQNPCYSGVACTFTSVAPFYTCGACPAGFTGDGETCDALQCPVGFAGIGDCAPDSDLDGFPDTELGCSSKYCRSLNAADNCPLMANSNQADADGDGLGDVCDNCPLNPNPGQEDVDEDLLGDACDDNVDLDGDGVEDSADNCPSVANSNQQDVDGDGDGDLCDLDSDNDGVNDPSDNCFLLPNPGQEDANGDGRGDACSTDFDGDRITDANDNCIKNPNVYATDFRQLQMIALEPQSASDPPVWVVYDNGAEIHQIVNSDPGLAIATKAMPSFMLWHGRRDHRTGLTRLRGHYLEAGGLCYRPWPSTSGCSVANWYHTNQATLLWHDGSIGWSPNVAYRWQLHHRPDIGTIRFYLYRGNNEVMDSGNIYDDSLKGGRLGLYCFSQEEIIWSNVKYTCEEFFHRRQATIVHNTEGEVATGVPCRARTEVLDLKRGSGRVRKSSSSVPHPVYLTRHNIFPLSPSLPLSLPPSLPSLPLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHX4</accession>
    <name>A0A3R7MHX4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023766</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000745">
        <property type="protein sequence ID" value="ROT83056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHX4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="170" mass="17827" checksum="AEC70649819A1C2C" modified="2019-04-10" version="1" fragment="single">MTNNLKEVTMETSGPENPPEGQTSAPHNNFRGRGSFRSRGGGFRGRGGPGFSAARGGGFRGRGAPGFSPGPMRARFRGRGGFRGGRGGPDGGYRGGFRGNFRGGFRGNTYGQNRVAVSEVVVVVLPVVVMVEVLVKVAATGEGTTVEAMEDVELLEDVAEETSMVDSRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MI13</accession>
    <name>A0A3R7MI13_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Triosephosphate isomerase</fullName>
            <ecNumber evidence="6 10">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_013397</name>
        <name evidence="12" type="ORF">C7M84_024532</name>
        <name evidence="13" type="ORF">C7M84_024537</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="6 10"/>
    <dbReference type="EMBL" id="QCYY01002665">
        <property type="protein sequence ID" value="ROT68435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01000848">
        <property type="protein sequence ID" value="ROT82294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01000848">
        <property type="protein sequence ID" value="ROT82299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MI13"/>
    <dbReference type="STRING" id="6689.A0A3R7MI13"/>
    <dbReference type="OrthoDB" id="6359622at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT68435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT82294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="267" mass="29328" checksum="F66B7A2BF6BD6392" modified="2019-04-10" version="1">MSSQRKFFVIGNWKMNVDKARIDNIVKFMSAASLDPNTEAVVGCPSCYLSYARQRLPDEIAVAAQNCYKVAHGNFSGEISPAMILDSGCEWVILGHPERRTIFKESDQLIAEKVAHAQQTGIKIIACLCETSEDREEGRTDDVLFGQMKSLAASISDWSRVVIAFEALWASNTGVLATAAQVQEALAKLRHWLRANVSDKVANSTRILYAGSVSSSNCRELAQLEDLDGFLVGSAALRPDIVDIINARRPDVSSLIAHFDRPDGRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIL1</accession>
    <name>A0A3R7MIL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024136</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000789">
        <property type="protein sequence ID" value="ROT82660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIL1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018697259" evidence="2">
        <location>
            <begin position="28"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="447" mass="50113" checksum="7AD4F396CB553B85" modified="2019-04-10" version="1">MEISAYAINRNSSLLFFLLCPSSFVFSSCFSSSSFSCFSSSSSSFSLFLPPPLSLPYSVSLLPSLIHFLVFSLLLFFLLPLSSFLPPFLHPPPHSPPSPFLLSFFVLPFPSFSFLFLLFLSFSFFLLPFPSPSFLFLLLFLFFSVFFSSSFPPFPSFLFLLPLFLSFSLLPSSPSFLLLLPPSFSFSLLPPSFPFSLLPFAPPFFLFLLPPSFSFLSSFLFLFLLLPFPSSGSLLIPFFLLLLRLSLLPPLPFPSCLSFSFSPPFLPFPFPTPPSFSFSLLSFPFFSSFSFSLLPFPSPSFLFLLPPSFSFFSFAFSFSHPSFSLLPPSLFLLRCACPFPFLPPSFSFFLLLFPSSSLLFLLPSFAFPSSSSFSFSSFFPSSFLSLLPSFLFPFFLPPSFSFFLLPFPSSSFLFLLPPSFSFFLLPFPSSFLPFPLPPFAFPSSSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MKV1</accession>
    <name>A0A3R7MKV1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001247">
        <property type="protein sequence ID" value="ROT79425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MKV1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="392" mass="42002" checksum="4BFBD9869397AFC1" modified="2019-04-10" version="1">MRIVCRRVAGTVNKDEEPITYRDVVVVIESIKYSAIHSLARLFAFFTISFLPSPPFISMSSPSPLLSHYSSSPITSSYDSLSPQSPFAFPSSPSLILSPSPPCHSPLMPLPLLIFLPTLSRYSLLPLSLTSHLPFAFPPPPCHIPSALIPPSSSTLSPFPSPPLPSYPNPLSFSSPCSLPPLSPSPLIHHSPIPLSPIPSLLIPSSPSTLFLFSSPFPLVLPSNELTLPLFPSPPFDSLLIPFLPISLSFPSPFPLLPLLLSPSPHHSLPYPPFLPLPPPSLPFLLPPPSPFSFGGLDTPSLIFTPSVLPLLLSLPLLAFHSSSSPPSLPPFFPSLPSPSPSSLPSFPPPHPLPPSLVLQLINALSSSPCQQHHLQIPSPFHLPVLIALTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MLJ9</accession>
    <name>A0A3R7MLJ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HMG box transcription factor BBX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_021855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000468">
        <property type="protein sequence ID" value="ROT84934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MLJ9"/>
    <dbReference type="STRING" id="6689.A0A3R7MLJ9"/>
    <dbReference type="OrthoDB" id="2377365at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21989">
        <property type="entry name" value="HMG-box_HBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049523">
        <property type="entry name" value="BBX_HMG-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052412">
        <property type="entry name" value="CC-Dev_Transcription_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13059:SF10">
        <property type="entry name" value="HMG BOX TRANSCRIPTION FACTOR BBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13059">
        <property type="entry name" value="HMG-BOX TRANSCRIPTION FACTOR BBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HMG box" evidence="8">
        <location>
            <begin position="83"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="6">
        <location>
            <begin position="83"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="41"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="369"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="574"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="613"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="636"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="725"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="737"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="766"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="817"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="848"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="936"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="955"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="966"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1008" mass="107850" checksum="C978E0C7E6D1369F" modified="2019-04-10" version="1">MYHPRLITTEVSQNGCVQDTNVLVFVIKTRRLTPSVNLRVAEREAEESRSGGESEGEGDLEDVVSPQQEDVSPQQEDAPPHPARRPMNAFLIFCKRHRAQVREKYPHLENRQVTKILGEWWADLPAQQKTSYTELARQYKEAFLRANPDFKWYKIPAQPPRPPPARPSNQKVPRCDPLPTDGAITFGKLADEAQMGGLSTLLSTASTSSSSNQNIASGPSSLTTFTTAYVSAANTSTARCAPIDSFPSVAALSTLSDVNSATSGSSNATANSTCGSSISTNTSVTTSLSTWSGTVQPSAVAPSVSPDSNNPAISNGPKPSTGSDPAVVTTSQSSVQSSLSETATNMTPPKPPKKRYVHANMLDQPVPVVSTQAQITPSPEKAKISSTEENAKSSASWTFSQGRQKPEGGAPPATEASEDQQRRVSNGPFSSRSVAGPPPGSPPRDAKASPQEANTPSEGTKPPPIGCSTPANVQPLNLTRETKLCTSNQEIIDSVVDRKCSEPNFPSSVPSETRPGYPRFFRPENLHNNNNNNNDIEKPSFPQAILNKVNGTYIKFCMSQAIHYVVDKAYDKGSKAKVTPKGDSGEKNQSAETNEKKEVEGENQVNTAKESVDSNNSNNSNPSDNANPTQRKRSKEKGPEENETSPKKRRDVPSGRASRETSRGMGGDTSGGRSRAPRKLKGKRYEELISEGVLQAPRRSRTRNSRWEETESSSAQDQEDEEDIQGQQPTQQIQQQDPEEEDHEDEPMEDDDAMNSKNEEENGEAGGRRTEDGGRKSRRQSRRLPPNDFDLEARIEALPSLNLDDFTRRKKEKKRTSSASSSSHAASHANVHSTSHPAPHTTQATLGVVSSSSRVAAQADSTSDPPPSASATSTATTTVTSWPTAGGVTSTSTSNGGTVGNTSDGEAVSPTPSSSSSTSSVTQQHSPSQGTLLVAGGSLSPGESGSSEGGPRIGSQKRKARKQTITRHDPVNGPLRRDTSVVEPSVLSSMAGLNALAEVALSQPSMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMZ9</accession>
    <name>A0A3R7MMZ9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_007396</name>
        <name evidence="18" type="ORF">C7M84_007397</name>
        <name evidence="16" type="ORF">C7M84_016159</name>
        <name evidence="19" type="ORF">C7M84_023557</name>
    </gene>
    <organism evidence="16 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 12">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003024">
        <property type="protein sequence ID" value="ROT65862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001933">
        <property type="protein sequence ID" value="ROT74105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01001933">
        <property type="protein sequence ID" value="ROT74106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="QCYY01000708">
        <property type="protein sequence ID" value="ROT83263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMZ9"/>
    <dbReference type="STRING" id="6689.A0A3R7MMZ9"/>
    <dbReference type="OrthoDB" id="6351678at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000020">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6 12" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="11 12" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="14">
        <location>
            <begin position="10"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="15">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT65862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT74105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT74106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT83263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13082" checksum="39A01CB3CCFECC39" modified="2019-04-10" version="1">MSGRGKGGKAKGKAKSRSSKAGLQFPVGRIHRLLRKGKYAERVGAGAPVYMAAVMEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPF9</accession>
    <name>A0A3R7MPF9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative splicing factor, arginine/serine-rich 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_015181</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002889">
        <property type="protein sequence ID" value="ROT66769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPF9"/>
    <dbReference type="STRING" id="6689.A0A3R7MPF9"/>
    <dbReference type="OrthoDB" id="7763451at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343:SF22">
        <property type="entry name" value="LD29830P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="138"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="254"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT66769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="310" mass="35327" checksum="B0F4D9D9C6D33A12" modified="2019-04-10" version="1">MSTLFGFLGKIEDIRLYPTIRDVAIPVQSRICFIKFHDRDSVSVAQHLTNTVFIDRALIVIPFTTGDMPDEQRAMEILGTGGTIPGIGQEAKWPAHVTNQIDGIILRTHDPALAENDLPDYPPLPATTESHKINEIRRTVVFDNLDPTVTTDQLMELAAKAGEVRYLRLGTEMNGARNALVEYSEQPFIIAALKMHNQEHMNRLIKVNHSTVAIIKPQTKSNEAAQREIEEAMRRVKEAQNFIASAIDPVMSFLDSSKEKRSRSRSRTRSRSRRRSRSRSRRSRSRRRTRSHSPRRSRSRTHPGITKRNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPH1</accession>
    <name>A0A3R7MPH1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_024382</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000821">
        <property type="protein sequence ID" value="ROT82457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPH1"/>
    <dbReference type="STRING" id="6689.A0A3R7MPH1"/>
    <dbReference type="OrthoDB" id="18894at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT82457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="220" mass="24843" checksum="D0C6C9CC2EFEF7E5" modified="2019-04-10" version="1">MRWSVVLLVVLIAGGLFLFTYKYTLFNLFGFILVLIASLLSGLRWTLSQLVMQKSELGLSNPIDMVYHIQPWMTVSLLPLAVIMEAIAASEYGFRFTDSSEALHMWGRVMFGAVLAFFMEVSEYLLVCFTSSLTFSISGVAKEIMTLSLAVYIYNEHLTNINVLGLFFCIIGIILHVVLKAMHPQKPPPPQHIPLTPAENYQKVPLLSESDDEEQELYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MRY4</accession>
    <name>A0A3R7MRY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000555">
        <property type="protein sequence ID" value="ROT84373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MRY4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="45414" checksum="B3404469B32F36DA" modified="2019-04-10" version="1">MLKLPSFRLPPLSSPSFPSTLLSPSPSFPSTLLLSSSLPLLPSTLPSPSLSSFLLLPSSSPPLLSLSTLSLPPPSFPSTLLFPSPFPSPPPPPLPSFPFYPLLSPPLLPFYPPLSSPSFLLPSSLPPFYPPSLPPLFLLPSSLLPSLPPSSLLLLPLPPPPSLLPSSLPPPPSFFALFSPTLLSFLPSFSSSLLPFYPPLSLPSFPSTLPLSPPLFPFYPSLSLPPSSLLPSLSLPLPSSSFSTLLLSLPSSLYLLLSSPSFPSLTLPLCLTLLSPSPFLLPSTLLSPTPFPFYPPLSLPLLPFYPPLSLPLLPFYPPLSYPLSLLPSSLPSPSFPSTFSLLPPFPSTSSLPPPPPLSLPSLLPFYSFSLPLLPSTLLSPSTSFPSTPFLHDTPPPFPISPIFSPLPYNPVIFSLFLILTLPNFPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MTH3</accession>
    <name>A0A3R7MTH3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat protein 36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_012484</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000258">
        <property type="protein sequence ID" value="ROT85528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MTH3"/>
    <dbReference type="STRING" id="6689.A0A3R7MTH3"/>
    <dbReference type="OrthoDB" id="539634at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000213">
        <property type="entry name" value="Tetratricopeptide repeat domain 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038906">
        <property type="entry name" value="TTC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405">
        <property type="entry name" value="CDNA SEQUENCE BC021608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT85528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="185" mass="20051" checksum="93D0D095FAB1BDB1" modified="2019-04-10" version="1">MASAGDRAILNSIFNPLLPVGECVYEEDIPKELKDTDDESPDCAEAKEQEILGVKAAEAGDVEGALVHFNRAIKITPSRPSGYNNRAQALRLQGKVEEAMADLNTAIDLSKGKGRAACQAFTQRAMIHRLQGNDDLAREDFQAASNLGSEFAKAQLVQMNPYAALCNKMLHDVFSKLQRGECAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MXM1</accession>
    <name>A0A3R7MXM1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">THO complex subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002208">
        <property type="protein sequence ID" value="ROT72098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MXM1"/>
    <dbReference type="STRING" id="6689.A0A3R7MXM1"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="357" mass="40399" checksum="5544D80211643FE1" modified="2019-04-10" version="1">MAGSHRLFTLETWKNWAKSGKAEVIQTIKQLLKEDSDNPGLSQPSVCKDLSRGLYEILSAVLRGSLTREHVRPLLAEMLNWHPDLASQLVEVATLLDLEASTIDRLSRNREQLMMLLKSLDIDKMMKERLEIETLGDYGIVKNKKNFHTKQIKVKTKLFYKQQKFNLLREETEGYAKLVTELNQEITERVTPQSIIQVIRSLIGGFNLDPNRVLDLILESLEARPSQHQFYTGLLNQYPCESATISELLGFKLNNYASNGKDTKGIYTTIALLIQANILQLSDIYSWLTPEDSSMIECHLKEENEAKEIGVQFTKPTQGLSSEATRQPSGTTTSQEIQRCQCNSIPNAACAWTTPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NCN8</accession>
    <name>A0A3R7NCN8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Paramyosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_023194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000660">
        <property type="protein sequence ID" value="ROT83626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NCN8"/>
    <dbReference type="STRING" id="6689.A0A3R7NCN8"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="7" id="KW-0518">Myosin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="12">
        <location>
            <begin position="22"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT83626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="261" mass="30215" checksum="6C4F6D237FB1FAE1" modified="2019-04-10" version="1">MEARVKEEQRLASEYREQYGIAERRFNALHGELEESRTLLEQSDRGRRHAESELNDAREQINTFTSQNAALSASKRKLEGEMQTLQADLEEMLSEAKNSEEKAKKAMLDAARLADELRSEQEHALTQEKMRKGLEVTVKDLQTRLEETESAAMKTGKKAISNLESRIRELEASLDDETRRHADSQKNLRKCERRIKELAFQGDEDKKNHDRMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKFRKAQQELEEADVSISVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NNU9</accession>
    <name>A0A3R7NNU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative Zn2+ transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019427</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003560">
        <property type="protein sequence ID" value="ROT62712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NNU9"/>
    <dbReference type="STRING" id="6689.A0A3R7NNU9"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010043">
        <property type="term" value="P:response to zinc ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000027">
        <property type="entry name" value="Zinc transporter ttm-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050681">
        <property type="entry name" value="CDF/SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562">
        <property type="entry name" value="CATION EFFLUX PROTEIN/ ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562:SF84">
        <property type="entry name" value="LD05335P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="197"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="12">
        <location>
            <begin position="424"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="132"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="326"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="515" mass="55969" checksum="03D39E714B681941" modified="2019-04-10" version="1">MRLKPGKKSKPIIWEEQLSPNVPAVYSHLGSVNMEERPSRDDTSLNSQNDDYEATNAIEADGVLDDKLLDAVTPRISVLDESVEDEDHPVKRTFCTRCRTISSSFLSTSYVSGSDNLPGIERLQQSRNSQTRFLGDQGHPASAGDSFEDSDDVPLLRDEDGAENGHAGMGPTTAATADHCHMPRASQRASSRAMTQLLLACCLTTVFMIAEAVGGYLASSIAIMSDAAHLFSDLTSFIVSLAAIYLSRQPASKNMSFGYYRAEVLGAVVSVLIIWVITGILVFAAVQRVISMDFEVEADTMIIVSALGVVINIILGVVLHMGQGGHGHSHGGLGGHGHSHSRRPSRAPENEQQSNNINVRAAFIHVLGDLIQSIGVLIAAYIIRYYPQYKIADPICTFIFSVLVIITTVPILKDLTHVLMEGTPQGVDYASVSANLTALPGVKMVHSLNVWALTLDKNACAVHIAISGDTDPETVLQAAQRVIRTRHQIFHTTIQVERYQPQLMDNCQQCQPLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NPX3</accession>
    <name>A0A3R7NPX3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003413">
        <property type="protein sequence ID" value="ROT63611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NPX3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="426"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="595"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="625" mass="68995" checksum="79DE95014C1A0444" modified="2019-04-10" version="1">MASSYLSSAYSPPSPPPLPLFPYTPFPALPVNSRLHPLPPPLPTPFLPLLLVSPSSLFPLPFPPPSPSSPRFQDPSSASRVFPFSLSSIPFSPFPPFLPCFPSPFGLSLPFPPFPPFRLFRPFPLPFPSLFFASPVFPLVTPVSPPFPSFSPSSPLPPRPIFSPPHPIPPSSLLPPLPPARGSERESPFGISLENSEDQTRHSDGTLSPRFLSCFLFSCSFSSLIFLFSSLLFSFSLCLSSSLSLSLSLSLLSLFSLFLFYLLLLPFSFRTISYFSSPFAIFFSPLSLFISFRYLLLLLPFSSHSANSFFPPPALPFFPLLLFFFLSFYSSFSSSLLLSLLSLYLPFSPLPQDLIFLFLFFLLLSLSFLSSSPSFNLSLFPFSSPSLLFLLFLSFSPSSSFPSPFFLFLLFPSFFPFFLFLSLSPLPLPLFLLFSSLLLFLLSSSSPSFPLSSFLSSLPLSHLPLLLSHFPSSSPYFLLPPFPHLFFLFFSSSPLSLLLSFSPSFTSSDSCYSSFSLPLLSPTFSLFLSFPSFSSFSSSSSFPLSPLLTVAIPFSACFPSALFTHTHTLSLSLSLVFSPSFSCSLPLFFSPFLSLSLSLSLFLSHFLFLLSFSTFSLCPSPSLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P118</accession>
    <name>A0A3R7P118_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002142">
        <property type="protein sequence ID" value="ROT72504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P118"/>
    <dbReference type="STRING" id="6689.A0A3R7P118"/>
    <dbReference type="OrthoDB" id="6368571at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF75">
        <property type="entry name" value="MYOSIN-16-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="8"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="516"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="566"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="604" mass="65357" checksum="73AC3A8C1D3DEA5A" modified="2019-04-10" version="1">MRDVARSSVATEIQVEEARREFSDLREKLARQEDLAKEFKAELDKTKQDLEEANKEKDDLALKLDSLEPQLKSLQEEQEILKQTNSDLKKAKEDLEDSLSTLRGELKDSQELVEEKTRIEDALRRRTKKLEDERTSLTRDLEKLKFRIHCLSRHAIREEGEHRGEVGRLKEQLNQKEEQLSEVKGQLEGKASDVNDLSAQVQRTEVEAAAVRGILESTQATLDQAYAKISQLEAQGDEEMKNVKAELAASKQALTERDSSIAALMASLSYISGHELFDLFVSGHGHCTLENYTPRLVTDGTLKLCFTNTCFFSPLPLPTPSSSPSQPTLSPPPPHHTPTPLPSQPPPLPPLPTPSSPHHLPNPSPNTPLFPPLPTPNPLSPSSPPPPPNPSPPPLPHHLPTPSPPTLPSPSPLPHFPSPPKPPSSPPLPSPPPPPNPLSPPPTPLPPPKPPPPLPLRTPSLSPPPPPTPSPPPLPPPPTPSPSSPPPPPNPPSPHPHPLPPLPPPPSSLPSNPLFPSHPPPSPPPLPTPSSPSHPLPPPTLLPLPPNPLSPLSPPHLPTPLLLPNTPLPLLPPTPPNPLPSKPPTPSPPTPPLPHHFPRTGEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P275</accession>
    <name>A0A3R7P275_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002031">
        <property type="protein sequence ID" value="ROT73360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P275"/>
    <dbReference type="STRING" id="6689.A0A3R7P275"/>
    <dbReference type="OrthoDB" id="6022711at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06759">
        <property type="entry name" value="PDZ3_PDZD2-PDZ1_hPro-IL-16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11324">
        <property type="entry name" value="IL16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11324:SF16">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="179"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="287" mass="31245" checksum="119A25287286FDD0" modified="2019-04-10" version="1">MRGLGRHLESCRSHRGCHRDLPELPATVGGARELPEDPGSARDFHHCCEHEARTYNSCDSRGATREPRDPRKRRRLDSLREEGVVTAVMVRTVSDSSSAGEEEPRRLLPLLEDGVFDERPSSQASQVSARTVASMASVASVHGTGLTAMSRQVSQRSHRPSSTSTLPRRPKSLNLSFHTVVFEKGHGKKGLGFSIVGGRDSPKGNIGIFVKTIFPSGQAAEEGTLKEGDEIFAVNGESLAGASHAEAIAMFKAIRTGKVVLHVGRRATSKKRAHKTKSFDDLDKFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P3F9</accession>
    <name>A0A3R7P3F9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Aminopeptidase</fullName>
            <ecNumber evidence="18">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">C7M84_007121</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="24 25" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="24">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 18">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16 18">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="18"/>
    <dbReference type="EMBL" id="QCYY01001906">
        <property type="protein sequence ID" value="ROT74378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P3F9"/>
    <dbReference type="OrthoDB" id="275509at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016285">
        <property type="term" value="F:alanyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1910:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.100.10:FF:000019">
        <property type="entry name" value="Thrombospondin type 1 domain containing 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044004">
        <property type="entry name" value="TSP1_spondin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19028">
        <property type="entry name" value="TSP1_spondin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 18 24" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 16 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 18" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 18" id="KW-0645">Protease</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="10 16 18" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="22">
        <location>
            <begin position="15"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="20">
        <location>
            <begin position="236"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="21">
        <location>
            <begin position="532"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="Spondin-like TSP1" evidence="23">
        <location>
            <begin position="900"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="649"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="870"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="649"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="704"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="872"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="17">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00052895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF19028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ROT74378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="960" mass="108927" checksum="3CB5A793AC4FC582" modified="2019-04-10" version="1">MPEPKPFERLPGNVKPLHYAVTLQPNLVKCVFTGSEDVDIEVKEATKQIKLNSLDLTLRDIKVTLASGEKVLPASTEISTPNEMVTLTFDKALPIGKAKLSMAFNGELNDKMKGLYRSKYTSVNGEERYSAVTQFEATDARRCFPCWDEPALKATFDITLVVPSDRVPLSNMPEISREQHESDTNLQVVKFATSPLMSTYLVAVVVGEYDFVEDTSTDGIKVRVYTPVGKKEQGKFALEVATKVLPYYKDYFNIAYPLPKMDLIAIADFSVGAMENWGLVTYRETCLLVDPDNTSASQRQWIALVVGHELAHQWFGNLVTMEWWTHLWLNEGYATFVEFLCVDHLFPEYDIWTQFVTNTYIRALELDCLKNSHPIEVPVGHPSEVDEIFDDISYSKGASVIRMLHCYLGDKDFRAGMNKYLTRHQYNNTYTEDLWAALKEASNKPVGEVMSSWTKQTGFPMISVTSHQDGDNKVLTLTQQRFLADGSTGDSSQWMVPISISTEKKPSETVKEVLLDCKSTQVVLEGISADTWVKLNPGTVGYYRTQYPPDMLDLLMPAMKSKCLPPLDRLGVLDDLFSMVQAGHTNTVEVLKLLKAFEDETDYTVWSAVHNCVARLNQLISHTDFHPSFAAFVRKLFVKIGQKLGWEAKPGEKTEKRPESLKETERPESLRDRETESLRAAERTKVRERPRDRKSERPRKIRKSEKTESLKRPRAGKSEDRETESLRDRRDLKTKEYTLSEHFDPADGTAYDVVKIEDIAYKHYGDEECNNASIALPGSLALLSSSFVTSAGLASLVCVVGPRPSATPWRSSYDTATEEEVSRNAFVNALPPSKTRDMAANRRVSLMSNSRIPTGDAMAVIDDIVKNYQKEQRRKMRKQRREQRRRRRMELRKIRPPRDCRVTEWSAWSPCSKTCGIGEQTRTRTILKHARRGGKACPVLEETTWCGSAGACPRDYFIWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P508</accession>
    <name>A0A3R7P508_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative pre-mRNA 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004195">
        <property type="protein sequence ID" value="ROT61399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P508"/>
    <dbReference type="STRING" id="6689.A0A3R7P508"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051187">
        <property type="entry name" value="Pre-mRNA_3'-end_processing_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484">
        <property type="entry name" value="FIP1-LIKE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13484:SF0">
        <property type="entry name" value="PRE-MRNA 3'-END-PROCESSING FACTOR FIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="6">
        <location>
            <begin position="81"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="155"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="317"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT61399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="362" mass="39337" checksum="CB4326F47A12EE81" modified="2019-04-10" version="1">MILPRHIDKEGDKEDGEKGDDDDSSDDDDLTVTIGTIKTQPDIIQAAPHGARFQPKAAPTTGLKDEDFTSPGKVNGVPVTEFNLDDLEDKPWRKPGADISDYFNYGFNEETWFKYCERQKRMRIQESGAGLTGLGISVTKPFGNTPSSIPVAIVNDNSKYGGSGSQRPKAGPPPRNKGMGQIDVIGGASNPKTSTIQVMTADRREYSNKVMMNGPPPPLPPSQPGYNDMEFGGNPYGDTYYGNEGNNFYGGGSYDNPSGWGSGGQPPMGNQGNWEGQGGGGGAPPNVLPVSGGGGYFDEDSVGAPPPSAEPEEERHRSRRSHRSRSRSPSRHRHSSRHPRSRSRSPSHRHKRKKSKRERDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5Q7</accession>
    <name>A0A3R7P5Q7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003912">
        <property type="protein sequence ID" value="ROT61939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5Q7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="489" mass="52949" checksum="76035DAADB1A5076" modified="2019-04-10" version="1">MPVTATAHAPGFTDGLTFDTLPRAITFRSRNLQQDTALRIRRRPVIGGGCLSAGLSEYGPSSTRVSPTPIPSSPSPRSIAPSPPSLPPSPSAPLSPPTTPFPSPPTARPLPPSPSLRPHPPLPHRQTRPPPPLSTQARSPADKIDTNSNMQTFHQMTPLHSSGYTQLCGILRLWLRPRGDRLCGPALCVQDVCVLQVKYLRERTRAENVEPSQGRRRSCASARHTDKLRGSPTGRLCNHEASPSSFSPSPPSSTSFSSSPPPLSSLSFSPVSLNFSPFYLLLLPQSPSLHPSSSLPSLLLPSLPQLFSTPPSTPPPPPSRLAALPPPPPHRRGTKPHNAHPEDKERRPDRRTAARVQAPPACFETAQVEELRGTPRPRRPEGALGLDTAAVRAQAGHATAAQLRHLLQHLHFLCLIHLIDVLHLLCRIQLSSMFSTTCVPYTSSPPPSSPPPLPPPPPRPLTVLHTSSRPRQTHAPLSFNLWKKKSFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P721</accession>
    <name>A0A3R7P721_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chymotrypsin BII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004128</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001549">
        <property type="protein sequence ID" value="ROT77233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P721"/>
    <dbReference type="STRING" id="6689.A0A3R7P721"/>
    <dbReference type="OrthoDB" id="60866at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000068">
        <property type="entry name" value="transmembrane protease serine 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050127">
        <property type="entry name" value="Serine_Proteases_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264:SF65">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24264">
        <property type="entry name" value="TRYPSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018526736" evidence="8">
        <location>
            <begin position="20"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="54"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT77233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="296" mass="31979" checksum="60DB1CAE3E2EDD50" modified="2019-04-10" version="1">MCAIIVFVFTAICYPAVAGVPIRQLTPVPPIEVPAKGPPLPESTGGPPPPGQRIVGGREALPHEHGYQACLLKKTRYLCGGAILSDMFILTSANCVSDSAQLYVLVGRYNLLEAESSSQRIPVGKVFIHPDFHASLSHLKADIALVKLKKKIDMNDKVFPIKLPTSDAYNGMPLVVTGWGKTLHAHGPGFIPLQVMETRAMSRMECMDAYGNVDIICTTSEFQTAAPCDGDFGSPAVFNDTVYGISSFISGCLHDDPRTIMSPRGPSRRQGYNLISRRGERLPGESRRGGAEGLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCX6</accession>
    <name>A0A3R7PCX6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003991">
        <property type="protein sequence ID" value="ROT61777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCX6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018622105" evidence="2">
        <location>
            <begin position="33"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="42110" checksum="8A2EB864DF2B3D80" modified="2019-04-10" version="1">MALSTSHQHSHFPSPPSPLLLLLLLLPSPSFPFSPSPSSPSPPSPLLSLLLHLPLHPQHSLQHYYSSPTPSHSLVSFPHSSSYPQLPIPPLTPTQTHSPSSCLPNSGPISPLSSIPFLNPHHHLPFLILPLCSPTFPTTNTITPAFQQHITPLPSLAPTYYPMYSPPPLANTHSALPLHPNKFPRRITHRHQHYRNYPAPSPNTVPRLPAPPTPKPHYPFPTSPPLPPSQQLYPFLYSPPRRRHTHPSSSLHPIHLPPLPHPSTPMPITPPTSNTSHPLPSAPSAPNTPPAMQPPTRIPQHPSHASPTAPLSPTVPHPNPITPPPFPNTGSPLTPLPFNNLTPLPRHPPEHHPITPFPQHPPHHPPTPNFPPPLTPPHTRANNSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGC8</accession>
    <name>A0A3R7PGC8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_010792</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002370">
        <property type="protein sequence ID" value="ROT70918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGC8"/>
    <dbReference type="STRING" id="6689.A0A3R7PGC8"/>
    <dbReference type="OrthoDB" id="265044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031681">
        <property type="term" value="F:G-protein beta-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052236">
        <property type="entry name" value="Small_GTPase_RasD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46149">
        <property type="entry name" value="MIP08469P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46149:SF3">
        <property type="entry name" value="MIP08469P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT70918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="196" mass="22013" checksum="7A312252AE430475" modified="2019-04-10" version="1">MGDLFVLVFSWDSQESWEEVVRLREQILETKMSASANCSGSRKKRASPRVPMVIAGNKCDREQMSASLEEVHAFVSSLSCCAYVETSAKKDHNVDKLFYELFVLANLPMEMSPALHKRVCPGQPSQESSPGFGSRHRGLSIRRRLSEAYGMVAPNVRRPSIRTDLLILRAKTSLHLTGIDAFTDKKPRREVSCVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ90</accession>
    <name>A0A3R7PJ90_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Selenoprotein W2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007941</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002014">
        <property type="protein sequence ID" value="ROT73615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ90"/>
    <dbReference type="STRING" id="6689.A0A3R7PJ90"/>
    <dbReference type="OrthoDB" id="5962009at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011893">
        <property type="entry name" value="Selenoprotein_Rdx-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02174">
        <property type="entry name" value="CXXU_selWTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10262">
        <property type="entry name" value="Rdx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="13992" checksum="2ACE581ED9FAC041" modified="2019-04-10" version="1">MRVRPRYEELARVIRSKVPQAEVVGAVGRRTSFEVSIDGTLIHSKIQTMSFPDFDEVADIVSSVDSGEAVRQLTAVTKANSTIQEENVALTRRIQEEREAVVRLRVQLQQAHKSIPHHPPVPPVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PKW3</accession>
    <name>A0A3R7PKW3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_006305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001806">
        <property type="protein sequence ID" value="ROT75160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PKW3"/>
    <dbReference type="STRING" id="6689.A0A3R7PKW3"/>
    <dbReference type="OrthoDB" id="10058133at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029336">
        <property type="entry name" value="DUF4594"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15266">
        <property type="entry name" value="DUF4594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="358"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="142"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="220"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="442"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="530"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="555"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="589"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="661"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="673"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="705"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="726"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="784"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT75160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="795" mass="88009" checksum="CB2FECD415E1BAEE" modified="2019-04-10" version="1">MEEVKPYVMKAPRVRPERAERQRDPADPPPPRPADVMPARQRLSENDGPPPDPSYRFLSDPDRDGSEQTRENRKEHRGRGGRGRASGARGRLRGRRGRQPPGRRLRRGESPENGAVPMGQGGRFASRDIRYFPDDEADAGAPRGGPGRGRGGYGPRHPHEEGEDGGRDRPRGRGRGGFEHRGRGRGRGRGQQKEYERWKAEREAIDEARLIRSRTHGGGWRREWDNDKLDQGNIEDSEPFYDPRYPRSKGEGFKLADYMTSGEGEDKGAGVQEGLGEHRPTRGRVSRGKYRGQGRYIDPELNAQKHEEEIMAELDPDAVFGRRRIEGHGDSFTISVSNTTHSSAGKFVRNSPYTWVRPSGAPAQTSSFAVSSQKSMEQDASDAPIPVAASESKADNNAIKPGAEKIVESNLKPDTNQEGNTIDENSQIESKEKGESGLLQEEIGENFEGSEDAAKEEELDDYEDEEVYEEAEEEYYEEDYHEAEEEELKGEEEETEEDLGATEIKENLPAEVESAPIQREEGKVEEEDSKQDSKARTDKEDHEPESQPVPVDVPEAEKQNTDENEGKEKETLDVKSEPKECAIQSEQELVSKDESPGKNNEQDVKENTEQEGECPRVADGEAVSEAAGKDKAGDEEKESSIVEDNAETEECPIEVGKEVSADDDITIDEEGTSVEKESDSKSNKDEDAQIENQPKDAASELPEPESGKERPSKLEVSEGKGEDSTAVGAAAISSEAAEPQAGVKVSESEKKTEGLVKLTPSPTKTNEGEKKPESRLTPSSSPTKTEELVRNIEWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTD8</accession>
    <name>A0A3R7PTD8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Metalloendopeptidase</fullName>
            <ecNumber evidence="10">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_004877</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01001647">
        <property type="protein sequence ID" value="ROT76534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTD8"/>
    <dbReference type="OrthoDB" id="291007at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9 10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018381833" description="Metalloendopeptidase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12A" evidence="12">
        <location>
            <begin position="153"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="11">
        <location>
            <begin position="385"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="11">
        <location>
            <begin position="545"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT76534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="664" mass="74189" checksum="E0216087FE85524B" modified="2019-04-10" version="1">MALRLALVLLLRALLVQSNEGNDISLTPDQAAALNLTSDRTAGNVKVGEMKRTIIDPDHIDEGDDMLFTANQSAALNLTERMMQDVETIEIDDLLLTRAQAAAIASRKAVNNVAQHWPDENGFPHTLNLLTALTIHPLSVSTNLTTTTRIHSKLLHQSEPPQHPHTPPFFNHTALVDRTAVEAAIQHWRDHTCITFTEVAQTETGPRLRFIRHASSCNSFVGYINRADGQIINVPEWCEESFGSLVHEIGHAMGFWHEQSRSDRDSYVSILTHNIRPAALGNFDLEVDNSYGVPYDYKSDMHYGGKGFTKNGLNTIVSIDPRYQDVMGQRTGLSHMDKLLANTMYGCTAKLLGTCGIASDPCQNYGFLGKDCNCVCPEGTSGSNCETLVTPYNDIGFAPNTEIVTEPKTITTVGYPSDFALYTDFVKWIKAPACKLIKITFTDFELYQKTDKTVDGVTVNACWHDHLELRTSNMLEGDWYCGTSISAGQEFITTGNEAVLYFQARTNFNRGFSADNGLPLSPGTILIPSAQFLATFTSNERYRWRGFNLRLRVKSDTETFGDGGVITSPMFPKPHRGTYCEWHITASEGKKVQIDVTHLRIRYSNFLAVNPTTELYYRRGSVIYLPHRWAPRQIVSDSNLIRILFAGKYGSKGFRIEYSEVDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PU35</accession>
    <name>A0A3R7PU35_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000796">
        <property type="protein sequence ID" value="ROT82622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PU35"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="394"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="464"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="542" mass="60452" checksum="136710874654DCB3" modified="2019-04-10" version="1">MVIVRTSGVVATPTSHTNYRQSQHPHNHTNHTVTSTTLPHIHTNHTAPPTTQLNQLHSHSNHTTTQPLQPHSHTIHTVTPTAEPYHLHNHTQPHLHTNQTFTPNQQSHTATPTTPPHSHTTVIPNHTVTPTTQPYTHTSTQSTPPHSHTTHTATLTTQPFQPQSHTNHTSTHPHIHTNTYTNHTATPTTQSHNHTSTPTTATPPHPPHHTHTTTHQHTPHTHRHAQPPPITSHNHTNHPPLHTTHACHHPHTAHQPHHTHPHSHTPATRPYNHTNHTATTHPHSHTTPTSTPTTQQHQRTTTTQSQATTPPTPITPNTQSHQPHHPRSHHPHPHHHTATATTQPPHHSTITQPHSHSNHTTTQTHPHSIHTSNTPHSHTNHTGNTQPTPSTQNTHTFHATHTPHIPTATLPTPTHPQQPTQHSNHATNPPTHHATHTNHNNHTAHQPHNHTTHTPHQPQPTQPQQPRKTTTHTATPPTQPQQPHSHTNHNNHTTHTTTTTTQPQQTNATTHPTPHHPHQPQQPYTHTTTPPTPPAIRTARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PU50</accession>
    <name>A0A3R7PU50_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat-containing protein mio</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_004232</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat mio family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001566">
        <property type="protein sequence ID" value="ROT77125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PU50"/>
    <dbReference type="STRING" id="6689.A0A3R7PU50"/>
    <dbReference type="OrthoDB" id="341486at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16691">
        <property type="entry name" value="mRING-H2-C3H3C2_Mio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037593">
        <property type="entry name" value="MIOS/Sea4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049092">
        <property type="entry name" value="MIOS_a-sol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031488">
        <property type="entry name" value="Zn_ribbon_mio"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453:SF9">
        <property type="entry name" value="GATOR COMPLEX PROTEIN MIOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16453">
        <property type="entry name" value="WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21719">
        <property type="entry name" value="MIOS_a-sol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21720">
        <property type="entry name" value="MIOS_WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17034">
        <property type="entry name" value="zinc_ribbon_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="MIOS-like alpha-solenoid" evidence="5">
        <location>
            <begin position="376"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="GATOR2 complex protein MIO zinc-ribbon like" evidence="4">
        <location>
            <begin position="716"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT77125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="868" mass="96950" checksum="926F2903D6B124D9" modified="2019-04-10" version="1">MSSVRVDVQWSPVAEDQFLTWGSDLQLYQVQEVSPTEIVQLPRLRLGPKTAASLLSTNNDLQYIKCVAWCPGLETDQSNQLIAVGQANGKVALTSFSKVPDPRGLKGREFIPKHSRAVNSLAWSTQEPKLLSAGLDKVRTDHSVLVWDVTRTKKIKIIEFGLAEASHSVAFSLHASGTLLTGMNNKHIKIFDLREGKLITTVSTKAVYGICTDPHNEHRFASYVENQVHIWDIRNIERPILYLDASKPTSKLAWCPSRVGLLASLSRDSAAVRTYDILHYNMGGEDQEPAVLTRSINTDTNTSLSAFSWHPTHENRILTASYTGKLVDYYVQERITLNWSSSTSSSLIWTHGKKTLYYLDSQHPVYSNFDDISIAIMSRAQKKYGLYEDNLATNGEVTGDMSLRDLWSWLDAARSLVTAGNFKLPGGVPYRYQGVLSLLTMGELMSDVVNKPWVGLDLQKAPTCKVFRCEERSRALELCSWGFENEAVLTSFLAQLENAGNYTRAAAVAVFNQRIKQAIQILQKGAAVKEPTLNSTAMALSGFTEDRKALWRETCMMLRSQLTDPYLRAMFAFLTDDADSFDPVLGETDMAIQDRVAFACNYLSDARLMEYLERLKMRLTEAGNLDGILLTGLCPEGIDLLQRYVDLTGDVQTVALVTIHTLQHAVNKDSRLSHWVQSYRNLLDSLRLWNERAQLDVIMNHNKYAERPPQHIYISCYFCNKSISAYIQAPGRPRNPYARYGTGSATKSKMQACPNCKKPLPRCSLCLVHMGTPSGWGSSTSKNLAVEEGADGQSNVPNNDGATAKRKLSNFTSWFTWCQTCRHGGHAHHLMEWFKEHTECPVTSCTCKCMSLDTVSKVPSSSAAVTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PV77</accession>
    <name>A0A3R7PV77_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000668">
        <property type="protein sequence ID" value="ROT83575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PV77"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="597" mass="64909" checksum="E3DAC212802CF0A8" modified="2019-04-10" version="1">MEERESLLAARLRRPLSLSFWNGERSLVKNRTILNPFLSHLLLIIKSEPEIKLFERSLPLHLSGFSLAPSPHCLSHFLPLAFPVFHSLSPLRPSLSLVSLSFSLSFPVFIPSLLSFIPSRSCLSFPLLPSFALSVFHSLLVSCLFTPSRFLSFIPSRSCLSFPSHSPCRSFSLALCFSLPLTPSRFLSFIPSRSLSVPLSVFSLLISCLSPLAPCQSPLSLFLSFTPSRSLSFTPSRSLFFTPSLSLPLCLSLPSLPVFHSLRSLSFTPSRSLSFTPSPSFTPSRSLSFTPSRSVFHSLSLPVFHSLSLPVFHSLSLRLSLPLAPCLFPLRSCLSLLSLPVFHSLSLRLSLSRPVFTPSRSCLSLPLAPVFHSSRSVFHSLSLPSSLLAPCLSLPLAPSFTPLAPCLSLPSPFTPSPCLSLPLAPCLSLPLALHSLSLPSFIPLAPVFNSSPPCLSLPLARLSFPLAPCLSFPLAPSSSLSPVFQSLSLPCLSPPLAPCLLLPLASNSMSSHLPSLYFLHLSPHCLTSSCFPLTPSFSLLISRSFSFAQSPSLSLFHTKPSCTRCHVHLLHVSLLLTSFLPCSCFPSYSLPRLPSAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWI6</accession>
    <name>A0A3R7PWI6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DnaJ homolog subfamily B member 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Testis and spermatogenesis cell-related protein 6</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Testis spermatocyte apoptosis-related gene 6 protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Testis spermatogenesis apoptosis-related gene 3 protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Testis spermatogenesis apoptosis-related gene 6 protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_021818</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. Component of the axonemal radial spoke complex 1 (RS1), at least composed of spoke head proteins RSPH1, RSPH3, RSPH9 and the cilia-specific component RSPH4A or sperm-specific component RSPH6A, spoke stalk proteins RSPH14, DNAJB13, DYDC1, ROPN1L and NME5, and the anchor protein IQUB. Interacts with SUN5. Interacts with IQUB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000466">
        <property type="protein sequence ID" value="ROT84938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWI6"/>
    <dbReference type="STRING" id="6689.A0A3R7PWI6"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036126">
        <property type="term" value="C:sperm flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000033">
        <property type="entry name" value="dnaJ homolog subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000006">
        <property type="entry name" value="DnaJ subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="15">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="14">
        <location>
            <begin position="71"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00064985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00071910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00078669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00080190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00081125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT84938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="48703" checksum="8AD06760B85F9FFF" modified="2019-04-10" version="1">MVKIEQPSELEDMISRVLGDGLEGLVLKKANGEYEPGKRHWLKIKKDSIYGGAMADTLDLVVLGSWKMAKDYYKILGLSKDASEGDIKRAYRNMALKYHPDKNKSNDAEEKFKLVAEAYEVLSDKKKRNIYDQYGDEGLKGGMPGGRSTGGTHFTYTYSGDPRATFEQVFGTNNPFSHFFNMGVDGHGTHDVFEDMLVGGGSHVGVKTRRTFSFNPHDNNPFSRFFNMDVDGLDGDPPRFRENKGRNQDSAVIRDLYVSLEEVFTGVTKKRKITRNVLLTADGRSTLREEKILTIEVKPGWKEGTKIIFEKEGDQSPGKIPADIIFIIRDKPHPLFKRDGANLVYTAKIPLRDALRGTLVSVPTLTGQRVALNFNKETTKPQTTRRLQGYGLPYPKNPTRKGDIIVHFDIQFPLNFSESTKAHVLKSLYLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q1C7</accession>
    <name>A0A3R7Q1C7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003002">
        <property type="protein sequence ID" value="ROT65996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q1C7"/>
    <dbReference type="OrthoDB" id="6357215at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053202">
        <property type="entry name" value="EGF_Rcpt_Signaling_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34009:SF2">
        <property type="entry name" value="PROTEIN STAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="133"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="303" mass="34789" checksum="4DE60EF75909047B" modified="2019-04-10" version="1">MEKLRRRLRSWRFFPLSGKTVTTSLLTVGLLALGVIHRDSGREARAAPEPAQTTSVAPVVVEDPNDLDFEGVVDDDPELLSYIRQHKLHPPAIHDKYDLRYPQKTDYSQYKQSTKIDKILKNMTSGFFVEVNAGDGEYKSQSLFFEVQRNWTGLLVEPDPAAFSEMKTKNRKAFSINACVSLLPKCTNKTLAIQNKTHPRSARKFWRIQCFPLYSLLLALNRTRIDLLSLSVGGDELKVLRTIPWHKMQIRLLEVQVNAIPEGEEAVEEFMAKVGYTYLGRCWIDRVFVRTELLDTVQRILTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q4B9</accession>
    <name>A0A3R7Q4B9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_013641</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01002704">
        <property type="protein sequence ID" value="ROT68230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q4B9"/>
    <dbReference type="STRING" id="6689.A0A3R7Q4B9"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08215">
        <property type="entry name" value="STKc_Nek"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051997">
        <property type="entry name" value="STK_NEK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44535">
        <property type="entry name" value="PROTEIN CBG16200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44535:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="4"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="401"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="453"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="15">
        <location>
            <begin position="575"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="254"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="261"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT68230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="698" mass="76152" checksum="4076DA9302CC3035" modified="2019-04-10" version="1">MNNYEILHPIGRGAYGNVYLYRRLSDNKHVVIKQIPTESITNAECEVTKNEVRVLAMFQHPNIIEYYDNYLDNNTIMIVMEYAPGGNLYDYLRSRGEGNLLPEEDVLNLFCQLIGDFGISKILSSKSKAHTVVGTPCYLSPELCQEKPYNQKSDIWALGCVLYEMLTLKRAFEAETIPALIMKIMRGIFAPIHPRYSAEMRSLVHLLLHMDPAQRPNIHQVISQPLIFPTLFKLHADLGMVRCVSRPLRLSSVGTRTRSSRGSEDSTDREKNEGEKKGVSEETRSVDKEVVKQPAASSCVYCWPPHGTPSRLSTGESEGEVLQVAASNTHHAGVTSAGQVVLWARQHLESKDRKGTKADNQDSPPSHVVPLTPTLVRAPSSATIVQVACGDGFMACVTNRGILLTCGKGSSGSLGHGNTSNVEQLRIVESLLSISVKEVACGSSHVVALSVDHQVFSWGCGDNGRLGIGSRKTQLWPHQIELPQVPDSSQYKVTGIEAGEDCTFLVTTEGVLFASGSNRSNKLCVDETDLAGCETLKQVEDVATFVAVCSKPLANAALAQVAAGKHHSLFVTESGEVFTSGSNAGGQLGHEGAHNPRVPRRVMEPLSRSQVVKVACARDLSLAVTEDGRVFSWGGGEAESEPSPPKEEVTAFEEPRIRTQNTFKNFVRPSLVSLKQSTRGKVLSIAASRELVLLCHKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QRA8</accession>
    <name>A0A3R7QRA8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001793">
        <property type="protein sequence ID" value="ROT75276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QRA8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="505" mass="55965" checksum="509E733645207067" modified="2019-04-10" version="1">MDTHMHKHKHKLPCLFRSLSWILCLFLSLSWLFFTLISLFCSFPPWLLCLSTLPSCLLVLPFPLWLLRLFFPFWSCLSFSLFWLLCLSFPFCSPFPLLAPVSLPFPLLVPASLLFPLLAPVSLPFPFLAPVSLPFPLLAPVSLPFPCLAPVSLSWLLCLFLSLFWLLCLSFPLLAPMSLLSWLLCLSLSLSGSCVSPFPPPGSCVSSFPCSGSCVSPFPSSGSCVSPFPSSGSCVSPFPFWLLCLSLSLSAPAFSPFSLFWLLCLFLSLFWLLCLSLSLFWLLCLFHSLFWLLCLSLSLFWLLRLSFPFLAPAVLPFLFCSWSLPSSLFLGSCVSPFPSSGSCVSPFPSSGSCVSPFPFWLLCLSFPSPALSLSGLCLSFLFSCVSPFPSLALLSLPFPLLAPVSLLFPLLAPVSLPFPLWLLSSWLLCLSLSLFWPLCLSLSLSWLSPFPLFWLLCPPFPLWLLCLSLSLSWLKVSLPFLLAPLFCASLVCSLFWLLCLSLSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYC6</accession>
    <name>A0A3R7QYC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proton-coupled amino acid transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_023643</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000722">
        <property type="protein sequence ID" value="ROT83183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYC6"/>
    <dbReference type="STRING" id="6689.A0A3R7QYC6"/>
    <dbReference type="OrthoDB" id="655540at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF703">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="6">
        <location>
            <begin position="32"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT83183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="409" mass="44582" checksum="9AF2840BB6C52D74" modified="2019-04-10" version="1">MSEGSKRSSVSTISGSIARMEAEPVGEKKEGLGMWMTSFFLIAQMAGAGFLSLPKALSNTGWLGVPMLILFCTMVGFSGTRLGKCWVILEERYPEYKNPCRQPYMEIADRALGVHGRRLTLVSVVITLMGGTIVFLILIASFLNGLIPQLSPCEWLLVVAAVILPFTWLGTPKDFWQASVLAVVSTAVACIVIFIQILVEVEEHEDPFYQNPTISTFALGFGAILFAFGGASVFPTIQNDMADRRQFGKSVVVGFAAILSLYLPVAVAGYAVRSKFETTLREPSLLVGHSCYYPRNHQPLWDLHHLLQPRRTEIKNPLFIHTFSHSNNPSPLSPSFPPLSPSLLPPSLSHPLPPSLSSLHPLLPPPSLHPLLPPFLSPSPAPSLPLSIPCSIPFPPSSPISLHTSIPTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMT7</accession>
    <name>A0A3R7SMT7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Adipocyte plasma membrane-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the strictosidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002771">
        <property type="protein sequence ID" value="ROT67715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMT7"/>
    <dbReference type="STRING" id="6689.A0A3R7SMT7"/>
    <dbReference type="OrthoDB" id="5307922at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018119">
        <property type="entry name" value="Strictosidine_synth_cons-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10426:SF88">
        <property type="entry name" value="ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10426">
        <property type="entry name" value="STRICTOSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20067">
        <property type="entry name" value="SSL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03088">
        <property type="entry name" value="Str_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Strictosidine synthase conserved region" evidence="6">
        <location>
            <begin position="173"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT67715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="484" mass="54270" checksum="7DDC8C5830095897" modified="2019-04-10" version="1">MVFSALCHLCTRSILDVAVLLLVLVLLPGIPPHVTYRSYEIDDPRPLEGRLEPNDILDASERILDGKIVGPESVASKSDDEIFVSLHGGKILRIWGKQFDHFKIITSIGPGCDGPWQEKICGRPLGLRFAPDGRLLVADAYLGLFSVDVETGEKERLFDPLEEIDGVAPKLLDDLDIDSEGNIYWSDASISADLSDGIIEMLSDPSGRLIKFDPKTKKNTVLMKNIHFANGVQLSPDHDFVLVCETFQKRVWRYWLQGPKAGASEIFVDRLPGMPDNLRNRNEGGYYVSLVAVKSPEAFDELKFLTKLPWLRKLLLRFVNLAKMVFDTVSKIYPNKFTEDISFKIFNLEPIAQHMASNKTIVVELDAEGNIDGSMQGNSGRLRFISQTNKIGDNIFFGSPYNKYLGRLEETVAESIPEKEPVRVEEEQPTPKEAEVSSAKEAEEAKKEETTAEPSMQEKEPIKETVSEKGKEKAEQDSVKKEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVV6</accession>
    <name>A0A3R7SVV6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001478">
        <property type="protein sequence ID" value="ROT77786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVV6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="737" mass="76864" checksum="08D8EDC017534A44" modified="2019-04-10" version="1">MAGPSGGCEGQITTLRCCDSPCLSSLPFSLRLSLFSSSFRLVSFSLSSFVPVSPSRPFCRSLCLSLSSVLSPCLSLSSVLFPCLSLSSFFVSLSLLSSSVCFPVSPSRSVSLSLLSSVCFPCLSLSSVSPLSLSPFNLPSPCLSLLSCLLPLALVSLSLPLPVSSPCSPSLPFSLLSLPLARLVPCLSLSPSPVSPPLLLSPVSSLPVSPLSRLSSPCLSSLPFSLPGLCLCPVSRSPCLSRLRLVSSVPSLLSPFSRPCLSLLPFSLPVSPLRPFSLLLSSRPLPVSPLSPSPCLSLSSRFSLSCPSPLLSPALVSLSLPLSPFRSPCSPLSRLVSLSLPLAFSLPVSPLARLVSLSLPLVPFSLPVSSPLPLPVFPGPRSFSSVHLCPLVPLSLRFVPCLSLSSRLVSRCLPLALYLPVSPLSRLVLPVSLSLPFSSLSLSPPRFSRLPVSLSRLVSLSLPLARLSLPVSPRVSPVLPLSLASFSLPGLSPSLPFSSPVSSSSPVCLPCLPLFASPVLSSARLVSLSLSPPLVSRSPLSHSFQSSLLGSLPVFPSPCLSSRPFSLPSLPLASPCLSSRPRLRCLSVSPFSPSYISLSLPLAASPSLTFSLAVSPSSPFSLPVSPLSPFSSPVSPLAFSLPVSSSLVSTSLPSRSFSLSSLPSRPFRSSLSPLLARLVSRPLPLALSLSLSLLARLVSLSLPLFSLPVSPSRSLPVSLPVSPLSARLVSLSLLSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T1Y9</accession>
    <name>A0A3R7T1Y9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000644</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000011">
        <property type="protein sequence ID" value="ROT86090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T1Y9"/>
    <dbReference type="OrthoDB" id="6373272at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT86090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="532" mass="60562" checksum="B3C384271C30E0BC" modified="2019-04-10" version="1">MFHLGSSHIALRPAVEAEVQALKEQGHIRVSSSEWNAPIVLVKRKDKSHPRLCVDYRALNSQTKLEFYPLPLIEDILYQVSQSKWFSTLDLRSGYHQVPLDDDSIPKSAFTTHEGHFEYTVMPFGLSNAPRTFQRLMNRVFSGQIGQGLQLFLDDIAIYTDDIDRHLQVLKEALGRLIKAGLKASPEKTRLFQQEINLLGHRVGHGEVKAALDKLAAVKDFPTPKNRREVRRFLGLTGYYRRFIEKYAQKAQPLTKLTSEKQPFIWGSEQEEAFEVLKRSLLKEPVLRSPDFSRTWYISTDASKGAIGAILAQRYDGHFCPVSYFSRQLRGAELRYDVMEKEALAVIEALKKFKPLIWGLEVIVMSDNRSLQWLFHKAKDGNARVTRWALTAQSFGAKILYHPGKLNAAADALSRIEAPEGVDPEDIEKASTMIIDEAQNCRILMAVVANNLGGKTRQDEQEDDEEDGHPWSIDEMIREQNQDPLYSPVIKYLQTKNLLDKRKVDPNLVVEDISLIKGSSTNKSGHLIQREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S922</accession>
    <name>A0A423S922_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative neural-cadherin isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_021823</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004663">
        <property type="protein sequence ID" value="ROT60646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S922"/>
    <dbReference type="STRING" id="6689.A0A423S922"/>
    <dbReference type="OrthoDB" id="6497475at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016342">
        <property type="term" value="C:catenin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008013">
        <property type="term" value="F:beta-catenin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045296">
        <property type="term" value="F:cadherin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031175">
        <property type="term" value="P:neuron projection development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11304">
        <property type="entry name" value="Cadherin_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.60:FF:000112">
        <property type="entry name" value="neural-cadherin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.60">
        <property type="entry name" value="Cadherins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039808">
        <property type="entry name" value="Cadherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020894">
        <property type="entry name" value="Cadherin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027:SF438">
        <property type="entry name" value="CADHERIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24027">
        <property type="entry name" value="CADHERIN-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00232">
        <property type="entry name" value="CADHERIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cadherin" evidence="7">
        <location>
            <begin position="444"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="279"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT60646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="569" mass="62363" checksum="898ED6C52781153A" modified="2019-05-08" version="1">MSAQTVFNALDRDPPNGKGVWRVKVRVQDGQRIFSRSRGRPEPPRTPQRAPRFNMEATEAEGGAWRGSSKSLRYLLDGNVADFSRHSDGGKQTSKRRRHWLSGSTRWREIRKREAPGAQDAGEEAIPEPEEILVSTTRWREAPQGGHSLPDEFRYHSRQNTNVAGSKRKRKRQTEGLSSKDPLRNDDGIHSGSIEEQRRSRRHISQHGVPLPPLSRLEPHDALSTLYPPTRRGKASAASAGSKGESEARVSSSADLPWRSQAAGEEVSELFKDRSAGLNRKGIQAHHLPTGASSSSKGRRGRTSSGSNAAQANDPEASEEGADAPPVWNPLALPLGESIRASRSARASSFRWNKHYLSYLVDQRDLLSDARRCKFVSIFDRNRSHYNVTDRDFQTAAGGGDAAGEEGRGWEVQGQVLRLEDTHFAETEVTVLVKDINDNAPVFPNATMYGAVQENGPADLSVAVVSAWDADDATEGTNARLSYSIEKNVVDEGSGEAIFAVEAETGVIRTALCCLDRETTPEYTIQVVATDGGGLKGECGRECGLFGAVLRGVWSFWAVLRECGLLGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9M5</accession>
    <name>A0A423S9M5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Neuropeptide GPCR A7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_021377</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004481">
        <property type="protein sequence ID" value="ROT60933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9M5"/>
    <dbReference type="OrthoDB" id="9046662at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042923">
        <property type="term" value="F:neuropeptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004983">
        <property type="term" value="F:neuropeptide Y receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15203">
        <property type="entry name" value="7tmA_NPYR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1070.10:FF:000291">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000611">
        <property type="entry name" value="NPY_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235:SF29">
        <property type="entry name" value="GH23382P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24235">
        <property type="entry name" value="NEUROPEPTIDE Y RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
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    <sequence length="455" mass="51422" checksum="5927B1E0E8604150" modified="2019-05-08" version="1">MSLLNLTSAPERSPGATPLSLTPNYTFLLSLVDSENRTVDANATSSDANLSAIETNILSYPTTQAIFYIEYMTIFLLGVFGNCLVCYVVFRNKAMQNVTNFFITNLALADILLCVLAVPFTPLYTFMEEWLFGRILCHLVTMAQGTSVYVSTLTLMSIAIDRFFVIIYPFRPRLRVPICYLIIVSIWLFSISATLPYALFVRQVEYQDRFYCEELWPSESIRQVFSLFTAIMQFVVPFIIILYCYVKISIRMNERVKAKPGSKSSRKEEADRERKRRTNRMLIAMVTIFGVSWLPMNVVHLVGDYYAPASTWDYYNLCFFITHVVAMSSTCYNPFLYAWLNENFRKEFQLVLPCFQQAPSTDRVGHWRSERTCNGNDTQQETLLASGAAAGGASAGRPPLRSQQSCANESPTSKAQATLEAHPLTTFIEVPPHANDGAHDQAVEPLVNGEASEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
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        <name type="scientific">Penaeus vannamei</name>
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        <name type="synonym">Litopenaeus vannamei</name>
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            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
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        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT61085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2193" mass="244379" checksum="AF8691C9B9E5C8FB" modified="2019-05-08" version="1">MWLPQPEDPPFLTVGTEVSAKYKGAFCEAKVHKVVKSVKVKVTFKLGLGSAVVPDDLVKGVLKIGAQVKASHPDKNQFVDAIVNKIQDCSQYTVVFDDGDITTLRRTSLCLKSGRHFAESETLDQLPLTHPEHFGTPVVGGRRGRRSRPHADGEDSGEEDDDVHKRHRSRREEWESDIGKVVCVELGDKKKQKDNWFPGLVVAPTAQDSVKIETKKDYLVRSFQDGRYYTVPKKEASPFSREVGSKVSQSALKTAVEKALLFMTNDELPPHWDRDLLFGTNVSDDDSDRDGSDSDSSDDEPREEKDHFVAQLYKFMEECGTPINSGPTVGNKDLDLYKLFKVVQKLGGFNRVMNQNQWKVVSNKMQLQSLGSQAPNHIKAAYKRYLQSFEDFYRKLGCTMNSPERESTGTKERSREAAGSRERSREPAMTRERSREPVVMRERSREPTAGKDKSRDSSSTSKERSRTDTSGKDQAGGEVVVKERAREPRTPRSEAKNRAAKGEAAEVKTRSSAKEERQEATPEVKTRSSTREERKEEKKEKEVKEESDSEEEEIEMAQTRSSRHREESREKDESTKKTATPTRKTKNERAAMAVICVKAEDDTEGDDETASSSSTTPTPVSSTHSGASVAASPASEKKANKSKSKGQKAVAVSAAAPITAEDSPGAKKRGRKKKNEGEVETPMIDRANSLPSRGKALLPAHVPVNVGDKLRVLYGPNAKESKVTYEAKVLEVEEEGNAPMYYVHYLGWNNRYDEWIRRPCIAENLTWSQNRVRKGRAAATKELKEKKEKEKEVKDTKDTKEAKKEEKEQVSTASSPKTSATKRGRPPGGMRERRESDRSERSDTSGTSSVSGPSTRAARERQVQQPDSPSPSEQRRPRRIGGGIGGGGSTLDTTESDSEEYESDADTGSEKSRTRSSTEKAPATASVSAVSTPVSEPSATVSTVSEKTVKETPAKVQVIEVKEEKVEQEPCGKDIDLNAIISEMKGLDKPIKKEEDRVVVKDTAPRILSPVMQTSFTTPEKKTPELQAKKVLEITPKKAIPESPGKNITQDPMKLLSPKPESLEDDVYEFKEPEPFDFGEIRARKDTRTKASMGALASDEAEADTKVKKKGRPRKDAKEGEGDKTESDSDTAPSPQKRIMLPREARESPVKWPISDVKEVAPQPEVSTTPEKKEAVAVTTIISPVRKVLIKRETPVKSEQATIQPTEVKVSKQESPKCPSPKQNQQEIPAPSLPMKEPVRINVTQIKAKPVNASDRGIAIPKPSGPTSHLLAQAVMPVIESKALAKPVPKPTFDAKVDKPPPVKSEDKVEAKVIPFSQRQQHIFPHLLNRPETSDKAKDVPQRITASAIQSPPRDSTPVLESTSLSQSGTSGRGKKVLSREFLPDTSEESDSDGRLSRPETERRTRRPRLVVDGEHAMIKRAQRLVSDTEKKKKGIIPPPGSLSKVKLSRRLDAEDQKEGEEAEVEGIRHIRKKPRASASATPKRYEEEGLGDLLCEETIPPGSPMTHDAITAEAELPQRPDMKHEMPFASVPTGSSFGKRGPVQPGGPQPPSNPTQPHVAQSQPSPQHQQMHQLPKQPQPQLPPQQKHQILVPQQKIQLPKTVQQQQQQQQQQQQQQQQQQQQQQQQQQKHEQLHHKQQQPQQQQQQQQQQQPKQQQQQQQPKQQQQQQPQQQPQQPSPSQPHPHHQPHLHAHHHHPSQSQLQSQSQPQAQPQALALPLPQLHQQQQQQQQQQQLHHHQPQQQHKPQQPKQQQLHPQQRTLQQQQLPLQQQQQPQQSPQLQQLQQVPQQSPPPQHHQPQLPHQSPKQQQQMPQVPQQQQLQQSPQQSPTQPPSQPLPPAQQLQISHQVQPHQQQPKQVQHQQQLQQSRPLQHQKSQSQTLVQPSNQPSQQQQQPEHGFQVSQAGQHLNQQKIQHPQHQKQQLYPATQSDHQQVQHQQQQQAYQRSHLQQQQHSQQHQQLSQDQHQHPPPTQPHQITPRLGPGISSAVISPNLAVVAAVAAAASPRNCGAAAGGSTASPSGGTGATSALPGAGAAAGAQAHSSAQATIDNTPPTTPESIISNISDSVKGDNEVSKLDESSKSGRDSSEVELESLADNSKMDQFSEAPVDDDNEASGLSTLSIACSAVRRSRYNFCQELDPDLDASKRIAVLQARIQELKRTYMQVKTELASVERRRKKLRRKEREKETKAEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SB76</accession>
    <name>A0A423SB76_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative pro-resilin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020749</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004146">
        <property type="protein sequence ID" value="ROT61460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SB76"/>
    <dbReference type="OrthoDB" id="6382835at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051217">
        <property type="entry name" value="Insect_Cuticle_Struc_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236:SF79">
        <property type="entry name" value="CUTICULAR PROTEIN 50CB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12236">
        <property type="entry name" value="STRUCTURAL CONTITUENT OF CUTICLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="394" mass="43643" checksum="A6616FFD00060AAE" modified="2019-05-08" version="1">MNASQTWRAIPDLRAVESALSPLQITFGAMITLQLAATVENSRPPSPPPQGASGYGFEYSVVDSTASWMHSRGEWSDGVSTHGAYHVQLPDGRVQRVSYTADEHGFRPVITYEEPHGYAGGFGWKVGGGSGLGKDVLEVDGLGAKEENGLGGRPHPGKDQVDVESRDVDEGHGGDIHPGEVYPGHGRGGRGHPRSDFVPVIYRQSYEPYSPYHDPPYYGSEPRRTYPSYRESPHAKVTHHGSPRGFPNHVGSPHHPRPAHDDPRHHVMHTTLKPRTYHINKTPAVGTRKPTNGHSKSHRLLTKEDKTPKGEMAGGHDPMEAHDMREEGHEVLTTLAPRLSMNDPIYRHDYSPMKCLAEDNQKRLRDKSVILSQPSSPHSPHRAMNLFYQLTPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCI5</accession>
    <name>A0A423SCI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat-containing protein 68</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_020279</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP1R37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003939">
        <property type="protein sequence ID" value="ROT61906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCI5"/>
    <dbReference type="OrthoDB" id="10034042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112:SF9">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="523"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="631"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="706"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="659"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="674"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="763"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="778" mass="83467" checksum="F3BC9CE9360FBD1D" modified="2019-05-08" version="1">MTDKQKEEQGIKDQPLSAPSTPIPPAAGHPRKSIRLQGCRGRRVSFPEDDTRLISSYLEPVNPWQQMSGVTVEEIAAAYRSSCERHRTQPLPTVVQQIKALPLGFGGRVECLSLRGQRLDGSQCEGLEEIFRRVQFKILDLEGCSLDDDTAIPLFDMIEFYDSATQLNISCNAKIGFRGWQACSRMLKRTPSVEYLDARNTNLNETNMPILGRALRLGARLHTLHLENCNLTGRPLIMLTAALKHNDTLAELYLAENRLGVNDCIQLGNLVRANNTLRLLDLRNNNVQDAGCGHVCEGIAEQQMQQIQEGNTQETESTRVKGLNSLVLWNNHLTQQSATHLASMLNVTTALETLNLGRNNLTSEGILRLKESLLRNRALLRLGLQAARVADEGAVALAEYTADNTAIQHIDLPGLCSSAPATPTGRSMSSGDLSSLPKQASVRPNRFSIGGRFTVTRVVESSAPSGPCSLPSSHTKVTATQSACTIPAATTAESPKIVISSPVRVERGFSVDGITTSVIPKQVLQQSEKLASTDTGSDQNKNVFDSDGLPAVQAGSQPPSGVHVRLKSDSSDGDDVFLDSPCLTSTNGRCSVVCKSGCDSRSTDKDADSVSSCDLTDSGFLDEGLCGRGAVSPSPSLCSPNPEGDRDSLLSSSVDSTSQEETGLGSSIDGSSNSILPGSLPSPMPLSSCNLPKPDKLQLAEPLKRAPLASMENGSFDSDSEDSEVTTQSSDSTHSDEVRITTEQYSPRPAWETKQEQVNVAKTSESSIVTSGTSSGTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCM8</accession>
    <name>A0A423SCM8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003904">
        <property type="protein sequence ID" value="ROT61956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCM8"/>
    <dbReference type="STRING" id="6689.A0A423SCM8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="683"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="721"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="960"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="721"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="991" mass="111182" checksum="604ECD6A34FADB62" modified="2019-05-08" version="1">MTPEPAISVTISTEKNNSATTEPAISTERTTVPPTASEPAISTEKTTVPPTASEPAISTERTTSEPAISERTTVPPTTPDLRSQQREQQSEPASQQREQQCHQRRQNLRSHTEKQCHQRRQNLHLNRENNSATASEISTNQTRMNLQSQQRKQQCHQRRQNLQSQQREQQCHQRRMNLQSQQRKQQCHQRVRTCISTERTTVTNDGTCDLNRENSATTTQNLQSQQRKQQCHQRRQNLQSQQREQQENNSPTNGVRTCYFNRENSAINGVRTCDPNRENNSATNGVRTCDLNRENNSATNGVRTCNLNRENNSAINDARTCDLNRENNSATNGVRTYNLNRENNSAINDARTCDLNRENNSATNGVRTYNLKRENNSAINDARTCDLNRENNSATNGVRTYNLNRENNSATNGVRTYNLNRENNSATNGVRTYNLNRKKNNSATNGVSNLNRENNSANGVRTYNLNRKQQCHQTSEPAISTEKTTVPPTASEPAISTEKTTVPPTASEPTISTERTTVPPTAENSATKDLNTVTPTASEPAISTERTTVPPTTPEPVISTERTTVPPTASEPAISTETTVPQHARTCVSTENNSATNDARTCDLNRDNSATNDARTCDLNRENNSATNDVRTCNLNRENNSATNGVGTCDLNREHSATNDARTCDLNRDNSATNDARTCDLNRENSSATNDTRNCNLNRDNSATNNARTCDLNREHSATNDARTCNLNRDNSATNDARTSKVDRQNTPTDHSGTLQQRDRLFRQRQQNPTPRQNLQLKSHAYQEANGHSGENNGIRIYSTCNLNRENNRIYNFNGENKCSIYNLNGEDKQTSYNGTYDARTCNLNRENSVTNDTRICNFNRENSVTNDTRTCNLNRENNSAIDDARICNLNRDKSATNDTRTCNLNRENKSAINDTRNCNLNRDNSATNDTRNCNLNRDNSATNDTRTCNLNRDNSTTNDARNCNLNRENNSATNDTRNGSRTRHLVKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGZ6</accession>
    <name>A0A423SGZ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Xaa-Pro aminopeptidase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_018673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003438">
        <property type="protein sequence ID" value="ROT63461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGZ6"/>
    <dbReference type="STRING" id="6689.A0A423SGZ6"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000007">
        <property type="entry name" value="Xaa-Pro aminopeptidase P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="750"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="Creatinase N-terminal" evidence="9">
        <location>
            <begin position="145"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="8">
        <location>
            <begin position="542"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="261"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT63461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="787" mass="87700" checksum="3803C9514E705025" modified="2019-05-08" version="1">MKKTPPPSDSRRNHLFRKSGLELSALGVVPRNCKCGSLSLRAFGRVYAAVGAGTQALRAGDHALHARVGRVAGISIPTERDDWAWTPERPSHGRRVVREVTLGERKQCGDDDQGPFTRVETAARCVAGRSGLGLECAWLAYWVAMLRAEMASEDLEAYIIPTDDEHQFNESGLLLVYTSGSSIWRSGRSINSVNEDLRGRASEYVADADKRRQYISGFSGSAGTAVVTMEQLALWTDGRYFLQADDELDCNWLLMKQKNPGKAKSKRSLRHFRNVPPGSSATDPSTAPCPQVPKMMDWLKQTLIPGSRVGADPRLIGADTWKKFAEELEKAEIVMVPLERNLVDAIWPVTERPPYSQDPIYVHELQFAGKRWEDKVAEVRIEMEKEGADLLVLTALDEVAWMLNLRGNDIPYNPANRLLLASCRPPFLSSTKEVMVVGRDSVELYIPGGKITPTVDNHLRVNQCGDQECVVINEYTAILNRLRALEVTNGVNKVMMGKKYSYSGGASYAIYSAVPEEKRVVATSPVLLMKARKNPTEVQGMIHSHVKDAVALCDFLAFLEREIGDSKYWSEISAAEKLTEYRAQQKDFMGISFTTISAYGANGAVVHYHPKPETNRQISNTSLYLLDSGGQYKDGTTDVTRTMHYGEPTPYQIETYTRVLMGAIDLAMLVVPEGTGDSDVDIVARRYLYEVGLDYRHGTGHGIGHFLNVHEAPTQVRIYGDEEHKFEVGQFFSDGCRGTMSRAGPSVSCLLPPLLFVYFSFLSFYFVVPFLSHVYTLSFPTDFDERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHI0</accession>
    <name>A0A423SHI0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Voltage-gated hydrogen channel 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Hydrogen voltage-gated channel 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_018487</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003408">
        <property type="protein sequence ID" value="ROT63625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHI0"/>
    <dbReference type="OrthoDB" id="427456at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030171">
        <property type="term" value="F:voltage-gated proton channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031846">
        <property type="entry name" value="Hvcn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480">
        <property type="entry name" value="F20B24.22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46480:SF1">
        <property type="entry name" value="VOLTAGE-GATED HYDROGEN CHANNEL 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="67"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT63625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="333" mass="37197" checksum="ED893F17F7D0C062" modified="2019-05-08" version="1">MEAISAKEGFPGSPEGAGEAIAVGVEGEDAEDKAVLKDDSVSDSSEASDLKPILDVRERLRQVMTSTAFQWTVVALVLLDSGLVIGELLLELGSHGTHTLAPWILHILSLTLLAVFTLEIALKLFAYRLEFFSHKAEVFDAIVVLVALCLDAVYLHADDARIGTGLIIILRIWRVVRIQNAMMLQVKHVADKKLKEERQRRLAVEEEHRRLLEYASTLKEKLREHDIDFEEDTPARRLFEKCASLSTLTLCLCSTHFRRIPIGKEHTVELLGNGGATLKTRVFPLMLNVWDSKHFQDAFRSALTGTMFEKGNRSICSNYLLSGAGKCFCDHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SKN8</accession>
    <name>A0A423SKN8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="4">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_017334</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="4"/>
    <dbReference type="EMBL" id="QCYY01003200">
        <property type="protein sequence ID" value="ROT64729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A423SKN8"/>
    <dbReference type="STRING" id="6689.A0A423SKN8"/>
    <dbReference type="OrthoDB" id="412600at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000085">
        <property type="entry name" value="E3 ubiquitin-protein ligase HECTD1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000014">
        <property type="entry name" value="E3 ubiquitin-protein ligase HECTD1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.20:FF:000372">
        <property type="entry name" value="Putative hect e3 ubiquitin ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010606">
        <property type="entry name" value="Mib_Herc2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037252">
        <property type="entry name" value="Mib_Herc2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06701">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159034">
        <property type="entry name" value="Mib/herc2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51416">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="338"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MIB/HERC2" evidence="7">
        <location>
            <begin position="1217"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1292"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1339"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1196"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1296"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1339"/>
            <end position="1360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT64729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1593" mass="173132" checksum="AC9F0BC390B90D51" modified="2019-05-08" version="1">MDPGVLMPAPSPSHSCPPRTFLPALCRIFLDECAPDNVLEVTARAITYYLDVSAECTRRITTVEGAIKAMCNRLVVADVTSRTSKDLAEQCIKVLELICTREAGAVFEAGGLNCVLSFIRDNGHLVHKDTLHSAMHLVSRLCGKMEPADPGLAPCVESLSTLLRHEDQHVADGALRCFASLADRFTRRAQDPAPLAQHCLVTHLLARLAENSKTSASVSTVISLLSTLCRGSPSITHNLLRSELPDAIEKALQGDERCVLDTMRLVDLLLVLLFEGRKALPKSGMSTVASRLPGLRRMDSSGEKTHRQLIDCIRSKDTDALIDAIDSGGIEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNKGQRSSSLHYAACFGRPQIAKVLLRHGANPDLRDEDGKTPLDKARERNDEGHREVAAILQSPAEWLVVADGKSTISSQDKKTVEEGNSANIEGEAEIGEPRGDVEMAPVYLSRLLPVFCHTFQATMVHTVRKASLSILRKMVHYIPAPLLHQVCGGEGTTISTSTNNINASTSTANTLLGSQLVEVIALVLGNEEDEDGHLVALQMVDDLLSKAAPLLLEHCARLGVISKVGSLAGPSDPPIEEYSSKGKDDQEQLTLGELLTSSHLFGLHRKEGDEPGMEDAKEVVPGKAYHWRDWCVARGRDCLYIWSDAAALELSNGSNGWFRFILDGKLATMYSSGSPEGGSESTAENRSEFLEKLQRAKSAVRPGSPSQPVLSTPGPARLVIGNWSLQCKKEGELHIHNSDGQQQATILREDLPGFIFESNRNTKHSFTAETSLGPEFHAGWTGRRGKRFRSKVEAMKQKVKGLARDVYEKYFKAAQTQPRGVVAKLGNIVAQIERACQKQVSNKNSGEWTEILRAAVEDLVTLLRDESTVSAYELHSSGLVQALLTLLSPGTAQHIPEDNRQVSQRRLNKMIKQRRNVFKSCFKTTPGESSLIDRNGRTLKMEPLATVEQLERYLLKMVAKQWYDFDRASFAFVRKLKEGQKLTFKCNRDFDENGIIYWIGTNAKTAYEWVNPASVGLVVVTSSEGRNLPYGRLEDILSRDPSALNCHTNDDKRAWFAIDLGVWFVPSAYTLRHARGYGRSALRNWMFQVSKDGMTWTTLYTHVDDCSLNEPGSTHTWFIQPQQDEKTGWRHVRIQQTGKNASGQTHYLSLSGLELYGTVTGVCEDLGRAAKEAEANLRRQRRLVKSQMVKHMVVGARVVRGLDWKWRDQDGNPPSEGTITGELHNGWIDVTWDHGASNSYRMGAEGKYDLKLAPGYDPESPQVSIVSTGISSSSSNTSTTSAPASSIPTITTAIKTTKVVSTEVSQGTSVLTSRKCSSTPSLPQATTDTHKHSVAASEQAASDDNLTAKAAETVAENVLSVASAEALLSVEGSGRDKGSELATLVQSLSLHDRDLTSDFSDAMSSLESVLNTSDIKSGTGDMSEAMTVMDVGLHPSADSSKSGHLAQAGECPAPMSVSVPNLTSADSEPLTHSLLETFAQVARRRGGSATMPPGSGICGSGGVAPHAPNVPASVTNMRTGLGQLIGGPPPTLAHPVFSPSTHSMSSLVRLALSSHFHLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNJ2</accession>
    <name>A0A423SNJ2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_016243</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003037">
        <property type="protein sequence ID" value="ROT65795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNJ2"/>
    <dbReference type="STRING" id="6689.A0A423SNJ2"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000008">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMP synthase C-terminal" evidence="6">
        <location>
            <begin position="197"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT65795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="289" mass="31930" checksum="FBA3B8F567EFAAF2" modified="2019-05-08" version="1">MPRAPRIRIPGVLSLQPSSSISELRLLSLFSSLPPSFSQHPLTWFARPPTPTANLLLTPLRHHSRADSGVTYTLTYTLPPAQQIKGQAITGAPYTQHTHHTTSHLIQPKQHSIGLKGDCRTYSYVCTLSCDSDPVWEDILILARLIPKICHNINRVCFAFGGAIKDLVQDITPTTLTPGVLATLRQADFLANQVLAESGFTEKLAQMPVVLIPVHFDRDPVTRLPSCQRSLVLRPFITHDFMTGIPALPGKHIIPELVNKMVAEMLGVPGISRVLYDFTSKPPGTTEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQC9</accession>
    <name>A0A423SQC9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative glycine receptor subunit alphaZ1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_015585</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002943">
        <property type="protein sequence ID" value="ROT66393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQC9"/>
    <dbReference type="STRING" id="6689.A0A423SQC9"/>
    <dbReference type="OrthoDB" id="6378843at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099095">
        <property type="term" value="F:ligand-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19049">
        <property type="entry name" value="LGIC_TM_anion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006029">
        <property type="entry name" value="Neurotrans-gated_channel_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02932">
        <property type="entry name" value="Neur_chan_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022263512" evidence="11">
        <location>
            <begin position="18"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="12">
        <location>
            <begin position="20"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel transmembrane" evidence="13">
        <location>
            <begin position="240"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT66393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="44502" checksum="74B1840328D11FBB" modified="2019-05-08" version="1">MEASVFLVAVMLALAEAQVDLLPASYLKHVRPKTPDGSPLRVGVSWHVSRIHQVDVDAMTVQLSVRPGVAWVDPRLNYTGEDHRDDHAHLLPLTLEFLEHAWKPDLFFLDMRDVRKFEMIDEVAGLWLLRNLTLYLSFLAMVTVDCPMRFHAYPFDVQNCSLAMTSYEYNREEVSLFWLPEGVSSSHQLTDQLPGYDLRLLPAVVTTHSWCQDCFLEPASALQSGFILSRRFSAHLLNAYVPSGLFVVVAWASFFWPPEVVPGRTVLVVTSLLTVVSMYTGVRATSPHTDYLKAIDIWFFMCILFNVLVLLQFGTVITLRRCQEKAKSAVVAPAPKGGAPHRLTPDLTQVKKLQRWEYHFELASKVLFPVAFVVFNLVYWGRFLSHREWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSI9</accession>
    <name>A0A423SSI9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_014765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002839">
        <property type="protein sequence ID" value="ROT67167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSI9"/>
    <dbReference type="STRING" id="6689.A0A423SSI9"/>
    <dbReference type="OrthoDB" id="6352072at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013106">
        <property type="entry name" value="Ig_V-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261">
        <property type="entry name" value="BEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21261:SF15">
        <property type="entry name" value="BEATEN PATH IIIA, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07686">
        <property type="entry name" value="V-set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="44"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="158"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT67167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="302" mass="33194" checksum="06D254AE99F3F1FC" modified="2019-05-08" version="1">MQGEDQPRRTANPPARWDDAKGAADAAGVRATSVPPEARQLLEPRGVEVPLYAVAGGRVNVSCMFDLGSTGLYSLKWYHNDTEFYRFVPTETHRSVDIKPTIKFQVHEVSRTDRQVTLSITSMTSAATGEYKCEVIAEHPSFRTETDSAIMTVLDETPSPPVITGTQELYEDGDIIKLRCLPESIPVSGPSPSIMWFIQGRPARREYVSPYREDTYSEESGKILQVPATQATKGNPPELFPRPRSPGWRPAGARLSHGWGGGAVVLVDSSPRDGPPKPEPELPPKLEPKPPPNPELDPPPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVG2</accession>
    <name>A0A423SVG2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Paramyosin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_013702</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Paramyosin is a major structural component of many thick filaments isolated from invertebrate muscles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the paramyosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002711">
        <property type="protein sequence ID" value="ROT68165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVG2"/>
    <dbReference type="STRING" id="6689.A0A423SVG2"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005923">
        <property type="term" value="C:bicellular tight junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030016">
        <property type="term" value="C:myofibril"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031033">
        <property type="term" value="P:myosin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000010">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349">
        <property type="entry name" value="CINGULIN-LIKE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46349:SF6">
        <property type="entry name" value="MYOSIN-6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="9" id="KW-0514">Muscle protein</keyword>
    <keyword evidence="7" id="KW-0518">Myosin</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0787">Thick filament</keyword>
    <feature type="domain" description="Myosin tail" evidence="12">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="49"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT68165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="313" mass="35767" checksum="1CFECD1D18AB4BED" modified="2019-05-08" version="1">MQASLEAEAKSKAEALRLKKKLESDIGELEIALDHANKANGDIQKQVKKAQAEMKDMQSRLEEEQRLASEYREQCSASERKANAVNGELEESRTLLEQSDRGRRQAESELADANESLSHLTAQHGSLSMAKRKLEGEIQTLHAELDDMLNEAKNSEDKAKKAMVDAARLADELRAEQDHAQNSEKMRKGLEVSVKDLQSRLDDFESSAHKTGKKALAKLEARIRELETQLDDEARRHADAQKNLRKCERRIKELSFQSDEDKKNHERMQDLVDKLQQKIKTYKRQIEEAEEIAALNLAKYRKAQQELESVHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVS4</accession>
    <name>A0A423SVS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative max-like protein X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_013563</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002694">
        <property type="protein sequence ID" value="ROT68307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVS4"/>
    <dbReference type="STRING" id="6689.A0A423SVS4"/>
    <dbReference type="OrthoDB" id="5778525at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19687">
        <property type="entry name" value="bHLHzip_Mlx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF25">
        <property type="entry name" value="MAX-LIKE PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="52"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT68307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="224" mass="25504" checksum="361FADC4ABDD405D" modified="2019-05-08" version="1">MTEEERDSDQRYPFSRCSSTGSIHTLTSSANNTDVTDDEDSDRGNQMSYKERRREAHTQAEQKRRNAINKGYDSLQDLVPTCQNSEQGQGYKMSKATVLQKSIDYIQFLKKEKAQQEKEVAALQKEVVALTIMKLNYEQIVSAHQSQPGQLNKQISDDVKFQVFRAVMDSLHQTFDQCVATNNFAEISGSVISWVEEHCKPQILREIMCGVLQQLGTHEAAFMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SWB6</accession>
    <name>A0A423SWB6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Regucalcin</fullName>
            <ecNumber evidence="7">3.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Gluconolactonase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">C7M84_013350</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="17">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucono-1,5-lactone + H2O = D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16217"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="EC" id="3.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SMP-30/CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.17" evidence="7"/>
    <dbReference type="EMBL" id="QCYY01002660">
        <property type="protein sequence ID" value="ROT68492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SWB6"/>
    <dbReference type="STRING" id="6689.A0A423SWB6"/>
    <dbReference type="OrthoDB" id="423498at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000027">
        <property type="entry name" value="Regucalcin homologue"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008367">
        <property type="entry name" value="Regucalcin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907:SF47">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01791">
        <property type="entry name" value="REGUCALCIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0106">Calcium</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="16">
        <location>
            <begin position="15"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="14">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00016808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROT68492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="327" mass="35467" checksum="39549C30867A14DB" modified="2019-05-08" version="1">MSGVEIKQVAPSVGLGEGPYWSQEDKALLFVDIVNGDVHRLFLETGRHQVLHVEADESGASVSLVIPVEGDRDLFLVGLGRSLAVVRWAVSDPDRHAVKAEAVLHTVDPQSPTNRFNDGKCDPQGRLWAGTMGFESTPGEPRLHQGSLFRLGHDLQLSHMVDKISIANGLAWSHDKKTFYYIDSCTYCVEAFDYDDNTGSISNRRPVLGYKAAGLQKDIPDGMCIDEAGNLWVANFYGKKVICVDPHAGKILRTVELPAQLTTSVCWGGPDYSTLFVTSARTGLTEEQLAAEPGEGGTFAITGLGARGVPPTKFKADMSLLRAKLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SX91</accession>
    <name>A0A423SX91_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_013012</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002628">
        <property type="protein sequence ID" value="ROT68835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SX91"/>
    <dbReference type="STRING" id="6689.A0A423SX91"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="380" mass="42278" checksum="053E7E25446B96FE" modified="2019-05-08" version="1">MTPWRMTPLWRMTLRRISPISSLSLSPPSHIYPQYIPLSISPPSTNISPLPPFPSFQYFFLPSLILPSPPISPLLTTFLISHLPFRQESPNTPPPSSPYNIPPSMLGVGFSSRSLSPSKHGGARVSVIYRDVEYQYLPYEDARPHFSFFPSPSILFLIPFHSSYYHAPFLSSSLLSLPCSVFPPSLHTISPFPPSPSIVLPPCSFPPPSFFAFLPLRSSPSYFPSLPLSLFHPFPPSSLLASLSFIGPFSSHPDYFVIALTLPPPPFHFVPFPRPPILTSISPFPSSSLFPNLASPFIPFPLPPPFHILLSIVCSFSPFHISSSILLSFSRCSLFAFPPILFLLPLFSLPPPFHVRLPSLLLTISPHSHRSFHILNLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXP2</accession>
    <name>A0A423SXP2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative reverse transcriptase-house mosquito</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002616">
        <property type="protein sequence ID" value="ROT69020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXP2"/>
    <dbReference type="OrthoDB" id="6373033at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33273:SF4">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="509"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="699" mass="78307" checksum="C513E702A2A8B7A4" modified="2019-05-08" version="1">MAKIKIKVLGGPSPRKRDLLANALYGAEIRVLRYIAIQDGYLALIDDDIQAEKLFSKDVVLSLEKLGFSPVLPVDMKAKLTLVFKNWTDEITAAFPEAQVDNIFVMKANHIIKVRFTDHATAKAIKEKGMYLFKLYVAPWQIEFERYTPIRQCMNCFGYGHLKNHCKEEKRPDALNVVPPPTHSGTVEVKAVAQKAAQETVQATTNAWKPLINQVRQDIKQKTPDPTIHLALPDNLSKEILVVLLHAHLQNLIAPEKGFRHHAKAALANNNLPDLDLGDSNSWGILKVIEPPTMTIQAPPEPQPQRPQPPQVQAPPQPQRPQPSQVQAPQPQPQRPQTVRVQVQEPQPAQMSEPQPAEAQTAAPQSSPQESSPTSAPPTTGPSVRPKYIHIPSEAETRDILSDTPLDTPGPPPPTPDQTEPGHSHVDDEGMERLMDGTATDPTYYGIRLFAENPKKYEYSDRYEIGQGRIKLLTKEEHAIVVTIKKLHQHLKDDLLAVEVNTPQGPIILATLYIPPRRQYIPEPDILQLLRHNKPIYIMGDFNAHHTLFGYNDTNAVGRGLASYIQQGRLTHLGPHTPTYIAHNAATTPDIVLANHIAHLHYHITTDDVTSSDHLPVIITLSTNPIMTPTQPRESFKHANWEGFKQALENTQVIDLEGQPTHMINNHLEQWYTDIQTAREANIPKTTYKTIPITEKHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZA1</accession>
    <name>A0A423SZA1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002574">
        <property type="protein sequence ID" value="ROT69338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZA1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="46508" checksum="8CF63AA125FE5F19" modified="2019-05-08" version="1">MLSPHPHTLALPPHALPTSLTPPSHLTPSPASSYPHHLTFDLEDILGHTSLVISHPLPTPPHPPLFASPRHFLLPFLPLLLPPLPPSQESLRLLPCTKSLASLPLPPPSLILYSPPSPPPLFPISPPFPPFPDSSTTSPPPHYLLLLPLLPPPLPNTPILLSHYTPHSPPALLTLHSPPCQPLPPRLTTPLLSKHSTPLLLPLPSPPIPSFLTPPSSRHCPLPLTPSFPLLLLYLLLLRHHPHSFAPRLSFVSSSLMRHLTSRTSPHSPLTPLTTPSLLPFSPVLLSLLPSFIFPFLLPLFFSLSPFPLDYFSPSPPLLFLPSNPLLFTLPFLNPHSFPIPLCLPFLFPLPLLLYPHPSLSPSLLFLFPFTPPLSLLTPLLSCSFYPSLSPSSSSLLSYPFSPPLSPSSSSLLSSPFSLPQPFPTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0I9</accession>
    <name>A0A423T0I9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011803</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002491">
        <property type="protein sequence ID" value="ROT69961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0I9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="45731" checksum="DB8B3CA97B511F89" modified="2019-05-08" version="1" fragment="single">PSAPPCAAGGGRSPPAPAPDKAPPTATSACPWPGAPPASGGPGAAANSSSPPGQPGFLGVALEVQRLQLPRQLVHAMRLRLAAQSPALTLAPLPLLRHLRREVQGPGLAPRAQRPRHVAVPEGPRGWLHGLQLAPLEGEHVQLEHQRVEGGRGRGGVRLQLRPALLEGTEPPFACSRPSRLQLPRQRVHGLRAPLPPEGLRSPPILPPPPGQPGFLGVVLEVQRLQLSRQLVQATRLRLAAQSPALTLAPLPLLVPLQRGSRARGRPPLPSALATSAGVTGSSSCSSRLACYCWRSACPLRLALCLALLFRSEYHLKAPRVAPRPPARTARGRACLVEHQRVEGGRGRGGRRLGMGLEALHAGEAYWRLLLLPPLLGGLLVLGLVRPRGLALCAALLASRGPRAIRRHPLRVRRSRTSWLCLRWSSKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0L8</accession>
    <name>A0A423T0L8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_011696</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002481">
        <property type="protein sequence ID" value="ROT70042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0L8"/>
    <dbReference type="STRING" id="6689.A0A423T0L8"/>
    <dbReference type="OrthoDB" id="10029564at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002142">
        <property type="term" value="C:stereocilia ankle link complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032426">
        <property type="term" value="C:stereocilium tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051844">
        <property type="entry name" value="USH2_Complex_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23116">
        <property type="entry name" value="PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23116:SF29">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="632"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="280"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="327"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="371"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="395"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="601"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT70042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="737" mass="83506" checksum="FEE79CE5A30C6334" modified="2019-05-08" version="1">MSDRRLRVGAASDVSSPSPAVLCLPRARMCRRQSTDSHLPSHPLEAALQTALPCVPHESLCARPGSPPSSPPPPPPCLRLMLAWCTASVRAQEMTSLFFLIALSLSKETDAYGEKISTISNLDDYIDIYNNMDIRGDGGEEELMSDHRVTDVAQRINKTPSEDSGVEMSNGALIPRRDIGRSLGERKRSGILIRENGSTIEGVTWADDEMNFRINNEEYELRREREERLCIGPKHQKILQKRFSERLLPNREELADHIQPQRRHSHTGEINGAACVKALPKPTHIPSHHAHQQRSTHTHAHARKQYVPYDSPTARKREEYDLLPTTRVREDYSAPQARLREDYDPPPRGRDEYDPPPSRGRGEYESPSGRVMEEYDPPARVRDTREDYDPPPPIVREDFDSPVRMRDEYDPPTRPREEYDPPARVREDYEPTARGREDYESPSRVREEYDPPARVREEYDPPARVREEYDPPARVREEYDPPARVREEFEPAARVREEYESPGRGREEYDPLLSSGRMREGYELRESYNQPPASHSRDDYDPAEDAFDPGSLSNSRDEYSPTRAREVFEGSPSRTHLSVEHRPMRASSPGPSPTSPSGRRGSAEVREDAHAPYSCRNRRTSLVVSDSLGRFRVVVKKTRPNLGIAIEGGADTKQKLPRVINIAANGAAFEAGGLRVGQLILAVDGQKLDGHKHEDAARLIAGCWVSRSRPEVEFMVVERKPTAADVRRSSISLLSQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2A4</accession>
    <name>A0A423T2A4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative homeobox protein 2-like isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002399">
        <property type="protein sequence ID" value="ROT70672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2A4"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18315">
        <property type="entry name" value="BTB_POZ_BAB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051095">
        <property type="entry name" value="Dros_DevTransReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110">
        <property type="entry name" value="BTB DOMAIN TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23110:SF109">
        <property type="entry name" value="FI07618P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="15"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="156" mass="17268" checksum="6D686EE76265EB4D" modified="2019-05-08" version="1">MTAVFDQLLQEEVFVDVTLSCEGGQQLRAHKVVLAACSPYFQAVLQNNPCKHPIVILPRDVAFADLRAIIEFVYRGEIDVAQEQINSLLAAADTLKIKGLCEVGDDPTHRLLLGRAQRLVFGEQPHTQGAGELYPWPLQHIIPPPRTPAALRQTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T399</accession>
    <name>A0A423T399_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative flocculation protein FLO11-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010703</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002360">
        <property type="protein sequence ID" value="ROT71002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T399"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="582"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="689"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="712"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="891"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="921"/>
            <end position="939"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="960" mass="102732" checksum="050CCE39A3B990EB" modified="2019-05-08" version="1">MNIWYRISQERMLYALKHRKNSCYYDHENTNQPAELDGACDAPFGQRHDRHEEDPEGAAEGRGLIPVSLQLNDILFKGRLVHLVKFRYVCFSFFLPLGLLFFFWCSPLPLGLPSLSGSPLPLGLLFFFLGSSPWSPLLSGLPFPLGLFSSSGLPSPLGLSSSFLPLPLAPPLLSGLPLPWPPPSFWAPLSPWPPPLFSGLHLGAPFLFGLPLPLASSGASSLFGLLLLGPSSSFGLPLPFPLGPPPFFSLLPLGHLLSFFPWAPFFPLATSSSFWAPFFPLASSSSFWAPFFPLATSSSFWAPLFPLASSSFWAPFFPLASSSSFWAPFFPLATSSSFWAPFFPLTSSSFWASFFPLASSSSFWAPLFPLASSSFWAPFFPLASSSSFGLPLPLGSSSSFWLPLPLGLLFFLGSLLPLGHLSSLGSLLPLASSLLSGLPSSLGLLLFFSGSPLPLGLLLFFLGPLFPWPPPLLSGLPSFSSLAPSSPWPPSFSGLPSSPWPPPLLSGLPSSLGLSSSGSPLPLDLLFFLAPSPLGLLFFLGSLLPLGLLFFLGSPLPLGLLFFLGSPLPLDLLFFLGSPLPLGLLFFLGFFLGSSWVPSPLASSSFWAPSSPWPPLFLGSSLPLSSSFWLPLFPWPPLLSGLPSSLGLSSFWAPSSPWPPFFLGSLSPWPPLLLWAPLAFLLSGLPSSPWPTLFLAPLFPLAFFFLGSPSSLGLLFFLGSLLPLGLLFFLAPSSPWPPPLLLSGLPFLASLSFWAPLSPWPPLLLALLASSSFWAPSSPWPPLLSGSLSWPPGSPSSPCLLSFWAPLSPWPPSFLGSPLPLGLLLFFLSSPLPLGLLLFFLGSPLPLGLLLFFLGSPLPLGLLLFFLGSPLPLGLLFFLGGSPLPLGRLLFFLGSPLPLGPLFFSPLPLGLLFFLGSPLPLGSLFLGLPSPLGLLFFGLPSPPWPPLLWAPLFPLPPSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T499</accession>
    <name>A0A423T499_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002318">
        <property type="protein sequence ID" value="ROT71261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T499"/>
    <dbReference type="OrthoDB" id="6387672at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="44996" checksum="009E4E8D59B9E517" modified="2019-05-08" version="1">MSSFSFQPQYNHELSRVRRLLLCGLWASSESLILLGTTAAAGTIAATTVTASAAAALGVGALAVLKGVLIGKHLKRRYRRDVDSMEIDDEAEVAVAKELDSAGCIAKLLCEIEATPADSLTPSMSTFKTAFENPDNLKSSRIEYDQAIALAKDDPKACSVRFNNTRRIRTAPRRCIHGFKISVFIERSRLTCILGYVPFPSHPGSGPSPALPPSSRYKYRALPGTNITLVLSLLQNTSRLRHHHEFSRVCRSPPVRPLGLLRVFILLGTTAAAGTIAATTVTASAAAALGVGALAVLKGVLIGKHLKRRYRRDVDSMEEDVATEIAVAQKMDSAGCVAKLLCEIEAMSADQLTPAMSTFKTAFDNNSNLKGSRGVYDLAITFGSKFAKKDAKACSALFDKCVLSRDDLSFMLDSTFSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4N3</accession>
    <name>A0A423T4N3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative organic cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010277</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002301">
        <property type="protein sequence ID" value="ROT71401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4N3"/>
    <dbReference type="OrthoDB" id="6884957at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="491" mass="53985" checksum="5AB0C41DC78A2809" modified="2019-05-08" version="1">MFRCNATLQGQDNSAIKAYSCHRFSANESLPPGQLMNVTSLSQLPPPDVPCDSGWDYDYDTLFSTLTSEHDWVCDEAWRPYLVVTAFWVGNTIGSWIFGTISDVYGRRPTILLIALVYGVAGVASVFVSDFYGFLALRTLVGSAHHTLSHLPFVLVVEYCGMDSRVVPLLTIMMTYTTASILAPSLAWLVWDWRILALLSSTPILLVLLMYRWIPESSSWLITRGRTQLATKQLETVAKINKRTLPGEKVNQLVSEGGDKSDEAAGEVASQSVIQVVRYRHLRNSILLVLLVWMLGCMCYYGHCQNTAHLGSNMFTSYLLGAAVEIPSWSAPWLINRLGRRLPLTVLFLLSGGASVLYALVPLDMEWLSLTLALVGRSTITGAYYITLQYGPEVFPTVVRGQGVALAETLGGVAIFLSPSIVYLGEILTTLPLLVFGGLSVIGGAATLFLPETNGVVLPQTLPQAERFCHRAARPFCRSKIEEETEMEAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T526</accession>
    <name>A0A423T526_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Turripeptide</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_010081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002276">
        <property type="protein sequence ID" value="ROT71594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T526"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050653">
        <property type="entry name" value="Prot_Inhib_GrowthFact_Antg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913:SF45">
        <property type="entry name" value="FOLLISTATIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10913">
        <property type="entry name" value="FOLLISTATIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0722">Serine protease inhibitor</keyword>
    <feature type="domain" description="Kazal-like" evidence="5">
        <location>
            <begin position="18"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="389"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT71594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="421" mass="46385" checksum="8B91FC8E9848DD3A" modified="2019-05-08" version="1">MVNWMDVVMSTTPSSQEGGKPRLCGRFCPLREELPVCGSDGKTYSSRCHLDNESCRDESITFKHHGECDEEKGETSSRCTSEVTKDNQGQVRGTHEVSIRIPENSKQATALSKSTQVFYKSAPEPASSTTAAPKGPAEPVQQPDPGNLPSPEQNNEPGEDEKKRSASTLEAPDDERRHLKGNEDRVKENQLRQKLMYDDPKCNIEKESKLLQMPQSQGRDNRIPEHAMLPPTPAGFTPIMAAPPSLLGYPPIITHTAATPQGSPHATLESCGRGELNNRLTPAMALYGSVWHYVRSAGTSSGRLEVSFDKEQQHNILSIISNLKSPGVPRFTQTRVPLPPRPARPPGLHQSISWPGAEREWRRLSAVLEKERVPAPATRIQHERRVVPAIASRQGEPSLSGLGLGIRRGGRDGPQQQHHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7W8</accession>
    <name>A0A423T7W8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002138">
        <property type="protein sequence ID" value="ROT72535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7W8"/>
    <dbReference type="OrthoDB" id="6378679at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="248" mass="27573" checksum="564C67EBE3CA7C30" modified="2019-05-08" version="1">MTPVPSHASLTKPIRHWELLRVCHKRYRWSWLLRQCDGRPAVRGSQNILSSPGHNTDPKTTADMIRYLLGSCLVAVLMVPTAANYGAPVPQVPSYGARPQQQACQTYVVTTTVATPQYFTETKYQTQYQTQYQTQYQTQYQTQYKTQYVTKKQPVSIYVTKTVSNYVTQTQQVNQYVTKTVPSYVTTTVKVPQYVTQSCQVSGGYGGSTGGGYSGNIGYGNSGGPPAIDIRQGPADEPTVGDDEWAWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBA3</accession>
    <name>A0A423TBA3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_007771</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001993">
        <property type="protein sequence ID" value="ROT73769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBA3"/>
    <dbReference type="SMR" id="A0A423TBA3"/>
    <dbReference type="STRING" id="6689.A0A423TBA3"/>
    <dbReference type="OrthoDB" id="10059102at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000077">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019504027" evidence="8">
        <location>
            <begin position="40"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="54"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT73769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="331" mass="35814" checksum="70C2D5C9B6BC5E99" modified="2019-05-08" version="1">MTQYHRRARLPPVSPRADDGGMRLLVLFLLFMVEVCVQSAVAPSHLQHLLSSRIVGGEDAVQGEFPFQVSIEHVGILGRNHICGGIVLSATDVLTAAHCISRFSEHNIDIVAGINRLSDTSSNRQTVEAVHFIIHEDFNDITMGSDIAIIRLKHALELNEWVQPVVMPKTGETAQEGEMCTVVGWGATFEDGDLSDVLQKVSVPIQSDSYCRSAYGYSAVEDSMLCAGSPEGGADACDGDRGGPMLCRGHLHGISSWGEGCGHSFYPGVYTEVSAFLHWNPKSTEDLELEALLGDDSAAPEETPSDDPEVQVVVAESPEDHDVPRELPPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBB3</accession>
    <name>A0A423TBB3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit I</fullName>
            <shortName evidence="7">eIF3i</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_007781</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the eIF-3 subunit I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001993">
        <property type="protein sequence ID" value="ROT73779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBB3"/>
    <dbReference type="STRING" id="6689.A0A423TBB3"/>
    <dbReference type="OrthoDB" id="24966at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000127">
        <property type="entry name" value="Eukaryotic translation initiation factor 3 subunit I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03008">
        <property type="entry name" value="eIF3i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027525">
        <property type="entry name" value="eIF3i"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24805">
        <property type="entry name" value="EIF3I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="2"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="44"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="181"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="279"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT73779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="323" mass="36297" checksum="58CF212BB2FEF170" modified="2019-05-08" version="1">MLQGHERSITQIKFNREGDLLFSASKDPKPNCWYSINGERLGTYDGHSGAVWSIDVKWDSTLFVTGSADQSMRIWDIETGTSLSNLEMKTSVRGVNFSYSGTMIAYTTDKMMGHNSELNIIDVRDPKDVDPTPIMKTQVTPNNAKALSVLWGPLDEYVITGHEDGCIIKWDMRTGKKIEIGQEHTKQIKDMQLSHDGLMLITASKDTTARLWDVGTLECLKMYKTDRPVNSAAITPLLDTYPHVVLGGGQEAMDVTQSRIGKFDARFFHLVFEEEFARVKGHFGPINSIAFHPNGKGYASGGEDGYVRVHVFDDAYYQFKFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBZ6</accession>
    <name>A0A423TBZ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001962">
        <property type="protein sequence ID" value="ROT73946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6381414at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="274"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="429" mass="48315" checksum="52402182EB5BF355" modified="2019-05-08" version="1">MINSKSAKIRKAAIPGTSFQYAAEEQALGTELFMGNDNDFELGEGFIDDDFDSFDAVGDFGSADDYILLPDVDLPPCSVVTQTPVGVDQSGSSTDCPEDVQLKDAELGDLLSEIDLGHLTLEQQQQLRQLSRAVAATELHNRDPDDLRRHQLEDPLWKEVIEYLEERNLPRRRLPLTLEEFELRDGVLYHVRHLPDRVLHQLVVPKTLRGSAMHLAHSSATAGHPGVYRTYCKLRDYFYFPNMLAAVKEYVGTCRSCQKRKGMAYRAPLAAAPQASYPLERVSADLMELEVTSQGNRYVLAFIDQLTRYVQLIPLPSKDAETVADAFINQFVTVFGPPRLLQTDNGREFKNNLFKRVCELASVQTIFTTAFHPQANGMIERTNRVVKNALATLLEASPLEWDELLPYVLLXRPLADLKIANGRLYINSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TET1</accession>
    <name>A0A423TET1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001823">
        <property type="protein sequence ID" value="ROT74999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423TET1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="921"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="983"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1251"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1315"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1474"/>
            <end position="1508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="929"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1277"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1474"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1490"/>
            <end position="1504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1553" mass="172569" checksum="9F3D04E8A915D327" modified="2019-05-08" version="1">MHDSHQGRIGVMRCCLMACSGVSYGWVLGSSAAWIGRWHGALAAVSSCRRLGRRRRLLRRELETEPSRFPPAYPPPAPLNALDFRTPWKPTPRPRWESRIWFDPDFAHNHRWDSSRTPSDGSRFPEDLGDVSRDRSDRVVEDEDSYWDAMQDSAMSTTRTPIQDFWDFFAMSDDRTEGTRATSHAEDLAEPLGSMSLIVTAASLVFIVLSMAGVSARTLPSLADALDNIQAFLFPDGGRKEEIAERVERAVSVYEGDTQTQTADPRISRIIDSVAHELQPVAHRLARQFDPFSQIAISAAMVLAAYVGYTVINPKQEVSIDKKDEDAASTLEHLFLEDADTEEKNVSIASNMEGEQSEHLTETDSQRDDYNKRFSLSDFSSVTAVSTLSDSKRGTLLNWGKQESPSTDLDFAVRPPDIRPHRKNNRFSVKYHAKPDDHHDQNGNTNFYTLSNLNDAFEATETYPQFEFVFPGEINRPDPNERFAQVDDPLSVIDAVSDHTPVAVNMESMNLYSLLTSDKLAVVDSSSRNKTPVPFIYSSNWLNDRQPSTDDERNDYDAINNASQYDTAQHNNDDDPYAAVTLEFHFEDNATQNGNLNTTQPMNPQRIGLFPLDRTPVSVNGSRMEYTDSTKHTVSEKNDAPDAVPSESKQKDVSGPSFFEIITSGYQIPNKGTQNDMKYSVSPDRPTSVDQKTQQAQPSPTPMLTNQVQSHSDYQHVDDITTNYVQSVDDRLHNSTLQYGEAYDPQLFSDEDALMQQSEILNFLLKEIAIGHLKQQIRTTEYPLLQNGNLDYKSQQNLHYRPQQNGFLNHNLQSSFSGYGAQGGMQSHLPQQSEPIVFQNQENAINPLQLEQTNTDSSYQHLNEAVHFQHDRITGSQKQHLNELSGYQEQQDEAIYQQNRYPSSQENKSDIYYQLQITPSGSAGSSSATQVYQSGPNSDTGNYHQETHGVNEMNNPQNEADYTLDDESFEALLEFARRQLAKGEPGQVTPQVTSGHPGLSVFSHTDSRPSRDPVGEFEELPYIPGGGNTAQSLDFAGAVPLDPHGAKYPGNTNQAGVDARPNLLPTSQDDFWNMNNENEYWEGQQDMDSGFSKFDDNENSDMGDGTNTTAGSHSYDELDLLALLLSQKGTLKRPTVAGDTVIVNGQEGTIDNENRNYTQPTAQASVNFLSGNDHKADHKQEYLNRGNNNNKNGEQPYGNAYEWDDQPTINDTQTTNKPLWPNRSKITAITPVPESLVTWVIPQKISTWSTLSDGRVSPVDGEENGTTPLPFSEASVPSTTTSTTTGPPSTIYEYDSASAASAHLTELPSFVRMSYPSVPPSTRTTRRPADLDPTRPRANGKFKNTPSSTLLELQGGDEEGTEIPTTLPGEDLFNQQSSISETSAVTLQSPGNPFTAETPYTPPPLRKQTRYLTTTTEVNSSSKLKPSFTIGFVATESTQHEPTYETHAPEGDTTPPNTSTPLSPYAISHDHYADTTTSQTANTVSEATRRPSTNTATPTTTSSSIGDKEAAKEVMNAVSLVNRFLCRHAVNEKACVLCLEEVGIRNECYSRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TH57</accession>
    <name>A0A423TH57_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005659</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TH57"/>
    <dbReference type="OrthoDB" id="6379363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="288" mass="31840" checksum="0C6B4AFB27D23640" modified="2019-05-08" version="1">MEGQLQFLITPFPLQWQSLQCGPEECLLQLPSGEAADEGRPEAFLARAQVAPGSCLYVPQAWQWQVRAEGDTTFLWLAWQDDLVLRDDVIAALFPLDDDDQGGGGEGVQAQGGGLRGGVPYISQTQDGRQGRNPTDPATLWEILPTDPLPPLVLWGEQDPLPHLLGQYLLPDLHLSFDAFFRRFRIDRLLLPDLVDCPPECQSLAASIFNLLDASADGLLNQLDATYLTRASVRSLTLQLDELLDELRDMGTEQWVHVVQVKVVTAGVSVLFVFVISSVDYISLVMIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TID1</accession>
    <name>A0A423TID1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM13A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001687">
        <property type="protein sequence ID" value="ROT76147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TID1"/>
    <dbReference type="STRING" id="6689.A0A423TID1"/>
    <dbReference type="OrthoDB" id="6340748at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039102">
        <property type="entry name" value="FAM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059029">
        <property type="entry name" value="FAM13A_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15904">
        <property type="entry name" value="FAM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15904:SF17">
        <property type="entry name" value="RHO-GAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26116">
        <property type="entry name" value="FAM13A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM13A-like" evidence="4">
        <location>
            <begin position="813"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="647"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="781"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="881"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="567"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="813"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="357"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="647"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="893"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="908"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="929"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="945"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="989"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="999"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1052"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1104"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1124"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1135" mass="127491" checksum="7830A9D205CB018D" modified="2019-05-08" version="1">MGQQGRRCTRKGRPSTPRTRARVFACEILSEPIARMSVGEFDFLKSFLLPPGVDDQRARCGANVTPPFSPTSPGKRKGELNCSSVPLAPAPADEQARDSGRSWFQRGTKPVPTNFPSKQVCWRSERDPVPRTPFCRSRGCGGEGRLYLPTFLPDVYPPAFYAYARTPLGSRGARSFGNVAPVSVRSAPRRKDLLSRRARGRGRTGRGKHRAASAAASAGHEDRPDTSADDALRKEQPPKEPLAEEAPDAFPGSLHRKRKEHADGKEGGEHDPKFIRSTREVVDHLDSIRPKVAPYSKELLVGPGVGPLLSPASPDDSLPSTQDEDEDATSQSPESSCVSAQDYWETGGESDLRDESERDEEEEEDFGGGGGGGGGLGVNDSHEERRLNERSFPRSYPQSSRRPRRRTKKRHHSHSPQDSSTRCQSSEDDERSSSYLRSLTSEEEEPTRYDPVPSDVVSCQPATGSVRPSSPVSREPSLGLSELLNAGEPVTSDRGSWGMRESSHCDSWHRTAPRYSRFDDESTMQSNWYRSDEDDIILSPRASEAFKDVGPANGSDDYKTPPGQGAVKILMKNINSIKKKIKRYEEEFESAFGYRPSHSEKMKHKEIKKYMSELSKARKELKQMKDDVAGMMSVPTVFPLSLLRCQESTNPNARPKNTSGTADTIRQVEDRLREKRSASGRPTELTNMNKTEMQEEKTALQKALLYYESVHGRPTTREDRDLARPLYDRYRQVKRIVMRSSSRAKENMVELAPILEHEAMDFTLASPQHRGSLQGDEIEKISLPPSPPSTPPVFESPDTRRGVPLGDLHALPLSELRERKKEARDEKKKLRRALREFEENFERDLGRKVQKEDRGPMEQTYLDYKHAKAKLRLLEALLSKHEPHKSHPPNHPPTVTHTHSYPPNHPPTHTHSHPPNHPPTHTHTHTHITQHPPQHTTSTQPPTHTHSHPPNHHPPHTHIHPTTHTHTHTHIHTTTPTHTHSHTQPPPHTHTLTSTNHPPHTHTHIHPTTHTHTHTPPTTHTHTLTHPPTHNDTHTHSHPPNTHHPHTLTSTQPPTHNDTHTLTFTQPPTHTHIHPTTHTHSHPPNYPPTMTHTHSHPPNHPQHSHPTTTTPTHTLTSTQPPTHTHTHIHPTTHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJ07</accession>
    <name>A0A423TJ07_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-type lectin protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_004964</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001661">
        <property type="protein sequence ID" value="ROT76438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJ07"/>
    <dbReference type="OrthoDB" id="441660at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019004522" evidence="1">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="40"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="161" mass="18509" checksum="6A7707620E95BCE2" modified="2019-05-08" version="1">MKLSWCLALLAALAVPSTGLDVFRNYKSLSRYCPAPFFNVGPECFYVNRAPKSWHQARAACQRMGGDLAEPTHTYVLLEALRDSHDSWEDKWFWTGGEIFNRGGDSSQWTWFSGRPVTEWSENQPQARDGEDCLMMGLDEDPPMYDYFCAEDYHSICELDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTK8</accession>
    <name>A0A423TTK8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_001487</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001187">
        <property type="protein sequence ID" value="ROT79796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTK8"/>
    <dbReference type="OrthoDB" id="10054572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="36"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="431"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="521"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT79796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="547" mass="59078" checksum="1AD61B9E241DD705" modified="2019-05-08" version="1">MLQNTKDKRNSEKGYASTDLRVADFLQHRRCQAGVARHDGAAREQRHVEFGSRPRPCTSRVSKGKALERIVTPSTQRLGTRTPERPPARVRRSRRYAPGPQKPRVPEEVVRGDGARGVSEGGGKKCAAARDRWRSPTVAPCDEAPRETGGREGGGASASPEPAVPRQLGWHRLRCGTQRDSGIEGPLLASHGRGDVPAQGNALLPIAGVLQALGCLGALRLSQRLLNIYWLLLLFLLLGDVVRAAKCCGVASPRDYNTTWWDAGQRFSVLRLPASCCQRNDSDAAEPGVRPLSGIKADQKVRHVKAYPETDAKGRLRADSYGGGGGRGRDRNLTCANGDDKEYYTRGCVVHLEKWLLTSAETLMILGFCVIAFIKLCFVGILRFEIQEMIQKIKVLQGETQCTPNPELAAALGLVSPDKAAECESVADTPLTQPRLNHLSGPTDGAESDTNSHCALITDTPVRRPQPDKRKPNGNNNDVTELRRQGHGAAAAPTTCEDAHTTPPFRVAACPPGDAFSAPLSLGLIPRPRAGRRDPRAPPGRLAASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUG0</accession>
    <name>A0A423TUG0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_001157</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001152">
        <property type="protein sequence ID" value="ROT80108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUG0"/>
    <dbReference type="STRING" id="6689.A0A423TUG0"/>
    <dbReference type="OrthoDB" id="2156623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF66">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GENGHIS KHAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="193"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT80108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="41484" checksum="BCAB6F1A425A6594" modified="2019-05-08" version="1">MYPLLSLHSHFHCFPPPPPFATPSLPHTSTLPFPSSTLCPLPLLPPPLPLCHSPSPLLLYHFPLPLSPLCHASPPCPLCNSRLLLSLCHSSLPTSLCHSTPPPSFPLSLPPLPSFLCHPLPPPLFPFATPLPLPSFPLPPLPSLFPLPLPLPSPLFPPFATPPLPLSALPSPPPLHLCHSPPTFSRRPRWLRFNSSSRSGRGGAAAASGRGSSRFYSAEAVVRMIDLSSLAVPVGEAETACFHEERDVLVYGDRRWITNLHYAFQDDSNLYLVMDYYCGGDLLTLLSKFEDRLPEDMARFYIAEMILAIDSIHKLRYVHRDIKPDNVLLDANGHIRLADFGSCLRLQEDGTVQSNVAVGTPDYISPEILRAMGEGQVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TUW0</accession>
    <name>A0A423TUW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative host cell factor 1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001139">
        <property type="protein sequence ID" value="ROT80238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TUW0"/>
    <dbReference type="OrthoDB" id="6372047at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41156">
        <property type="entry name" value="AGAP006184-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41156:SF1">
        <property type="entry name" value="ZASP-LIKE MOTIF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="821" mass="86878" checksum="4425DF8BF240EF4E" modified="2019-05-08" version="1">MSQRMQESPFRETEWDQRLDRMLDDLKTTVGSDGEMSGTEGRSDPRDSSLCSDPRGQSRAPSPDERVDGTFLDIFRSSSRSEPRSSSRGGSRTGSALGMVEDGGHMKHSRREYLSPDEKTHVVTEKYEYDTGDTSKTSHYQKKVMKSTYSSYNSMSAGSLDDPPTHALESPPQTSRPAGTKGTTTSSGLTNGTAPASQPTRYDGDDEMIDDKSGEVRRIVWRNRFEKTYETQDSRPTATVSIEDEARRRQLVQRQQQHTSTSASTSTLSSPPGPSSPPQVSPGSQSWKDPIPMPTPPQLSPREPGVAYIYTYGNTGGSGVQHMPPLNYVTVPGPSSVPPSEGAPSPTPSQLQGPQPIIYHYSYHYTIQPGQPLPDGAPPPPGGLPSGSQPALQMAPSSQPPSSSTETIRTIHQTTSGQPGQPGQPGQPGQPGQLVHPGQPGEPAQPGQPGYPGQPSSTVSSYNIHSYSSSSRSKTSTLTHTDTSTVYPGGPGGPDGPHGPGGPHGPGGPHGPGGPHSPSGPYGPGGPHGPGAPGGPDGPRGPTGPGYDGPAHPSKPYGPGEPDGPGRTTEPGQPGNISITINKTTTTRTTHAFPGGPDHPGGAGDVPPVTSTPYPSRGRSVSPEPHGPRSNSPHHVTYVTHVTRNTHSDSLDRVRRPKNETLPFPNTSPIRPAGDNKIPRRVDDLMTSFSDSEDGPGHPRHSPHRGDPADQQPLLPQNSQIVVKADADAKALAEANADPKKEPTKNKAGPPVYYPPGHELFHETMHTMTLREGGGRRGKAKWRMERSAGYKESSSHSESKGGMTMVPVCLPLCCGAACVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZW6</accession>
    <name>A0A423TZW6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000898">
        <property type="protein sequence ID" value="ROT81986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZW6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="46716" checksum="25841DA4B44B0AE2" modified="2019-05-08" version="1">MAAVAGGEVDGFLKEGESSFKSSSSLPFPGLEIHLPPSSSPSSSIPLPPSPCSFPSTSPPTSPIPLPPPPFPHPRLHSPISPPSIPSFPLPSSSSPPASPPPLHIPSPSPAHLFHSLPPPSSHSPDPLPTTTSSFPPALPPPFISPPPSSFASPLPPPSHSPTSPPSLFHSPPPSPHLFIPALPLPLHPRHLSSFALPPPAPYPIFLRYWNISPLFLSPIILSPPPAPFTLLNFSSLSPHSPFRHFLLFPPPPLSSSSPLPPFLLPPPLAVLPPFPSSSPLPFIHRFPSTLSLARFPSSSPLPLSILLPIFLSVPPLRSLPLSPLSLLAPLLLLSPFSAFLLPSPSFFLSVLPPSLPLSPLSLFSLSSSLLSLYASPSHPYPSSFLFSPHPLFPPHSPLPSSHSPLPLPPFFFLASLPLSFVPHLPPLPPYPPLPLSRTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0K7</accession>
    <name>A0A423U0K7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyl galactosaminyl transferase 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024589</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000854">
        <property type="protein sequence ID" value="ROT82243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0K7"/>
    <dbReference type="STRING" id="6689.A0A423U0K7"/>
    <dbReference type="OrthoDB" id="9982049at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004653">
        <property type="term" value="F:polypeptide N-acetylgalactosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11675:SF134">
        <property type="entry name" value="N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="3">
        <location>
            <begin position="94"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="298" mass="33612" checksum="033D17313A8B64F6" modified="2019-05-08" version="1" fragment="single">MFPESGVVPGGAQPLKDWHNLTQERLDRLRSGPGEHGAPHHLTAGREKERDALFETNGFNALLSDDLALDRSLKDIRHPKCQEKRYAAALPTVSVVIPFFEEHWTTLLRTVVSVANRSPKHLLKQIILVDDGSTMKAFLKEPLETWLAEHVPIAQVVRLPERRGLITARQEGAKKVTADVIVVLDSHCEVMINWLPPLLDPIVRNPRTAVCPLIDVINKDTFAYSPQDNGGRGAFDWRLYYKRLPLPPEDEARLPEPFENPVMNGGLFAISRKFFWELGGYDPGLAIWGGEQYDLSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U164</accession>
    <name>A0A423U164_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000822">
        <property type="protein sequence ID" value="ROT82444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U164"/>
    <dbReference type="OrthoDB" id="6728016at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="470" mass="51366" checksum="4FB14313E904860D" modified="2019-05-08" version="1">MAIFECDRAGLLHRRSVAILSRTQAIDEMFVRRVRRLLDVAEVGHGALSTISHDTCRKTGQHNWHVDEELFGLLPGVDEGQVRRRVSDGVQDYDITQLEIIGDGIEDESFRGSLKDKRPAPSLLSSPYCKQVDSSVSCDFKDTEEPVFLDELPTPRTSKVFLHNAGSVTVAAKVCIHLAFFSVSSITFAKNSECPADAKTSLRLVDSGANLVPPQVIRLDMEDSSATVLDTEAEMESLNLQRSSLGVLHAPKPFRANTIIKLEHSTISSLDGLVLEGSQLLMINTTVDTIRKHAIQLRDSSGSIWVSSFRQTYDQALLLGAKSTLTLKGVDGKITLAGSEEASSLRHIPTTTAPPPTTSPPSREPLPPGVPPKNRAKDLPAPCPRGSSIFWLLPTGVALVEAMIIMINCTNWFPALKSGRFRRGVEEGGRRTNTLEGVATSFNPIPAFYYSNEPAGFPSTTMRNRHDKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U1C9</accession>
    <name>A0A423U1C9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000811">
        <property type="protein sequence ID" value="ROT82526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U1C9"/>
    <dbReference type="STRING" id="6689.A0A423U1C9"/>
    <dbReference type="OrthoDB" id="6364363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF43">
        <property type="entry name" value="LP10131P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="107"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="224"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="1">
        <location>
            <begin position="341"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="53509" checksum="A983C1A72CA4EF6E" modified="2019-05-08" version="1">MALWIPSELWPMPLAAEASQSLSNCLDPSVSRKAKSSYIKAGLQAQSSVRFHVSLLSSPSVPLTNGNGVTVYANGVVDPFRALADAIGGGGVPGVDYPILAFVPATGFSCNGQLPGYYADTAPEAGCQVFHICQAGGRIDSFLCPNGTVFNQQYFVCDWWYNFDCSTAEQFYGLNAEIGYQNGNGVTVYANGVVDPFRALADAIGGGGVPGVDYPILAFVPATGFSCNGQLPGYYADTAPEAGCQVFHICQAGGRIDSFLCPNGTVFNQQYFVCDWWYNFDCSTAEQFYGLNAEIGYQNGNGVTVYANGVVDPFRALADAIGGGGVPGVDYPILAFVPATGFSCNGQLPGYYADTAPEAGCQVFHICQAGGRIDSFLCPNGTVFNQQYFVCDWWYNFDCSTAEQFYGLNAEIGNINGNGYSNGNGNGNGYTNGNGNGNEMDIRGNGYTNGNGNGNGYGYTTVMVTATVDMEMDTPTATVMVEMDTPTANGNGNGWVMVMDIPTATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2Q2</accession>
    <name>A0A423U2Q2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative exportin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_023830</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000753">
        <property type="protein sequence ID" value="ROT83001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2Q2"/>
    <dbReference type="STRING" id="6689.A0A423U2Q2"/>
    <dbReference type="OrthoDB" id="2215036at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042565">
        <property type="term" value="C:RNA nuclear export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045478">
        <property type="entry name" value="Exportin-5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF3">
        <property type="entry name" value="EXPORTIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19273">
        <property type="entry name" value="Exportin-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="2">
        <location>
            <begin position="36"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="3">
        <location>
            <begin position="112"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-5 C-terminal" evidence="4">
        <location>
            <begin position="314"/>
            <end position="1125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT83001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1179" mass="133218" checksum="B576C8213A94D300" modified="2019-05-08" version="1">MDVSSQVAEMAGQLAQAVNTTMDPTVPHAVRLASYNLLEKVKEESEVAVGCGFHMAHPAKEPVVRHLGLQLLEHTIKYKWNDLSVQQKVFIKENTMQLVTDGTLDLLTEQLYVKDKVSRLVVEMMKREWPQQWPGLLDELHALSKRGPTQTELVLFVFLRIAEDVATLQNLESNQRRRDLYQAMTANMESMFGFFLSLLEENYKLYEATMKAQNLQPAQQHCRVMQVVLMTLTVYVEWVSVQHIFADDGKLLKSLCFLLSEDNLKMEAAECLLQIVSRKGKLDERRPLILLFGKAPMSTIFAAADRAVMGTLSEHNYRFLKTLTQVLTALGSQLCALWGKEADVGEPPNFRVYLDAMLAFTGHPSLHIYNFTNGLWGQLFRHEHIPQSKTLQAVLPSWITIVSRMVMKHGYPSKNDSESCQYSRLDFDSDEDYSYFFYKVRSETLETIKAASLLAPETLYSFVEEWLKNQVKKAADQGQQDKQLCNLFSPFYLEWEALSQVLESVMSRVMQSEGYKPTAESGLELLRLCLSYQTTDPLILSTLLSCISGLFVFIRLVPSVLPDVLNKIFSALTFSLPGQTKDSRSRAVKNVRRHGCSLMVKIARSYPDILLEAFDFINGVVDSLSHNPQELSQMEKVTLQESLMIINNHFHNFEKQSTFIGKVLGPVSEIWLNMKQPFSSPLDFMSFVGLDKAPVEPSENDVNGQNRAQIIFCVNLIMAVIKRSEFPTDTDVAERGGFILERSDSGAVFCRNPATPHVMPLLHQLFCLVRLFNALWHPEALACVSPGYSKAHNLPEAERNNILGLATINSSDPCIDSPKVQQPLERMQFFLSMMHDNCYHILGNAGVSLGLQFYQHPHLTDYLVHSSLANLHLIPDYRLRPIIRTFLKPFIQWCPPQCYQTVLLPILNHLCPFMLDRLSTRWGHLTSLIESGSYEEENTDTQEMLEDLLIRMLTREYVDLLKVVLIGGPRGDLGQLVLGCDTICQAIVTTLLKVLWWQDSGACLKAVGVVGQVLRWLVGEGQHLSPDAVRQVLLAVLQGLHTHGQHDANQSALLSLGLATYELFRPHFPNIREVLLGLPGVSAEDVQRFEEKILNPNAAAKSSKTEKIKKDNFKKLVIEIVGRNVGQAFKKEVHMNNLPPMFKNPRPKQPRVDDTDADIGLCSLFGPDLAESNGHQATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U486</accession>
    <name>A0A423U486_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Benzoate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000673">
        <property type="protein sequence ID" value="ROT83538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U486"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="488"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="562"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="652"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="688"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="743" mass="79625" checksum="937CF7375CA41E2B" modified="2019-05-08" version="1">MPSGLSPNLRGLYWLLPFPSLKSVPSSPFPLLAFSSFFASSFPLLVLCFFLSPFFPKASCGLSAFFLPPSFCFFAGPLSFPVLFLSFCLASLSPLLLAFCNLLPCLSSFRGPLPFPLLAFSIAFFLFSPRFFVGLFLSLFPSFCYPLNFSLSLLFYGFSFLSPSPKLLLLCLFSFPLLSSSLLPSQGPRPPSWPLLLPGSVFSLSLVFCCSISCALFLCASLELFASSLSLLLAFCFCGFSFPFSCFCASCLSSLNFLCLFLPSPSFSSVPPPFFFPPLSLPSLPSPFPLPSLFFPPLFFLPLATSFPSFCALPFPLLAFCASFLSSPSFCALFLPSPSFCASSLPFLSSCLLLCLLPFSLLLASLPLGLSSPSSVILPLPFLSFCASFFPSPSFCVSSFPSPSFCASSFPSPSFCASFFPSPSFCASSFPSPSFCASSLPLLSSVPLPFPLLASVPLPLPLLASVPLPFPLLASVPLPFPRLASLLYLYFPLPSFCASSSPLLLLCLIPSSPSFLCLFLFPLLASGAFFLWPVPIFCASFFPSLASVPLSFPSPSSVLLPFSLLSFCAYFLFPLLASVPLPLPVLSSCASSFPSLNLLVPLLSLSYFCASSFRLLASVLSSFPPPSFWASSFPSPSFCASSFSSPSVFASFFPSPSFCASFLLLASVPLPFPLLASVPLPYPLLSSLLCLLPFPLLASLPLAFLFLSFSDSSSPFPFLCASSFPSPKLLLPRPRLCSLLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U489</accession>
    <name>A0A423U489_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000675">
        <property type="protein sequence ID" value="ROT83507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U489"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="471" mass="52748" checksum="CBB04992184939E8" modified="2019-05-08" version="1">MGAVRRILLVCKLAGTFPYSIDRGAFAVQPPWVVWTVIRCLLVTITASHLLVRCAPLTSGVDGMTDAIWVYTYTLCFFVTALCTAFASSRLAAFFRMLGSLNPSEMAEGRGSPRDAVKIHAVLTLLFASVMVIGYGFFNVPVTLGNDEIPWYVASYVAIWLLAGIPCVNSFLLFVILTWKLKSMSHRIVSELLLEKFAIRTRGETQTCKSFDISTTGGSRSDRTPPAAFRVFDLVSAARQTNGNPEIHSSRHPEKEQLMINNLLIVENHLIEISEMVEQLMRHYNLMLIALSLAICSAVTLSWYFLIDEYLSTSKLKWINLYAVIFGKGLYIAMTLGPDLFNAQRLEDGRAVRRRLPAAADPPLLFAVSWPPSVIRPWEMLRCFRFVLDFIRLLTAVWLFETAADRVLSLLEHRQEFSLLGFINLSLTNVASLDNLPLLTARQPPPPESLTSVRFLLDTCTCQLDNLPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5K4</accession>
    <name>A0A423U5K4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative arrestin-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022843</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000613">
        <property type="protein sequence ID" value="ROT83969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5K4"/>
    <dbReference type="STRING" id="6689.A0A423U5K4"/>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016060">
        <property type="term" value="P:negative regulation of phospholipase C-activating phototransduction signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045494">
        <property type="term" value="P:photoreceptor cell maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007608">
        <property type="term" value="P:sensory perception of smell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.840:FF:000002">
        <property type="entry name" value="Arrestin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017864">
        <property type="entry name" value="Arrestin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF23">
        <property type="entry name" value="PHOSRESTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00309">
        <property type="entry name" value="ARRESTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00295">
        <property type="entry name" value="ARRESTINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="191"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="41610" checksum="6DDA0DA21B892C29" modified="2019-05-08" version="1">MVNAVKVFKKTAPNGKITVYLGRRDFVDNTTSTEPVDGVIVCDNDYLRGRKVFAAVTVTYRYGREEDEVMGLNFSKEMQLATQQVYPSSDSREPTAVQERLVKKLGANAYPFAVTLPETAPCSVQLHSGDDETSKPMGVIYELRVFVGDHSNEKPHKRNSVALAVRKVQFSPVAGNKRQPSTLVSKGFALSSGKLNMEVTLDKELYYHGEQVNATININNGSKKTVKNIKCSIIQHVEVTMTSNQFSREVASLESKEGCPITPGCNLQKSFNMTPLASSNKSKSGIALDGKLKDTDANLASSTVVAAGKNVNDACGIIVSYSMRVKLNCGAIGGDLTADLPFKLMHPVAGAPAKGRGDATYTGGEDLEFEDFARLRRGVSVDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U6J3</accession>
    <name>A0A423U6J3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SEC13 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_022506</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000564">
        <property type="protein sequence ID" value="ROT84302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U6J3"/>
    <dbReference type="STRING" id="6689.A0A423U6J3"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090114">
        <property type="term" value="P:COPII-coated vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032527">
        <property type="term" value="P:protein exit from endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000017">
        <property type="entry name" value="SEC13 homolog (S. cerevisiae)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4-like_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="6 14" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 4-like WD40" evidence="15">
        <location>
            <begin position="72"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="207"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT84302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="312" mass="34516" checksum="A0D2D4391A4E852A" modified="2019-05-08" version="1">MVSVISNVETGHDDMIHDAQMDFYGTRLATCSSDRSIKIFEVKGSTQTQIADLREHEGPVWQVAWAHPMYGNILASCSYDRKVIVWREDGHKWKKIYEYANHDSSVNSVCWAPHEHGLILACASSDGSVSILTYTSAHTWENKKITNAHSIGCNAVSWAPAVASGSADGSNRTASAVQRIVTGGCDTYVKIWRFDSGTGEWTEESKLEGHSDWVRDVAWAPSIGLPRSIIASCSQDRRVIIWMNDGVTGTWQPRELNTFDDVIWHVSWSVTGNILAVSGGDNKVSLWKETLEGQWVCLSDSAKGHSGTERTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9J6</accession>
    <name>A0A423U9J6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_015651</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000296">
        <property type="protein sequence ID" value="ROT85375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9J6"/>
    <dbReference type="STRING" id="6689.A0A423U9J6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT85375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="147" mass="16234" checksum="55E9AB06EB1DFBCD" modified="2019-05-08" version="1">MFQGRKQRILGFLACVLMGLICFSLAAMYFPLLVFKARKFALLFTLGSLFSVLSFSFLWGPVNHLKHLFSSERLVFTSVYFLSLFATLYFALSLQSTIFTSIAAIVQVVALLCFVLSNVPGGQTGLKFFSSICSSMVKTTVSKALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2022-12-14" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LPU8</accession>
    <name>A0A3R7LPU8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004292">
        <property type="protein sequence ID" value="ROT61206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LPU8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="42692" checksum="2E049933BD0FF83E" modified="2019-04-10" version="1">MTLSSFTGPAAWSRARAERSAIAYLRIQSVVFTAIKHEQFSGRADRGEPGSPAAAAAPGGRAVAPSVTTCTRRRGSWHQKMTLPQLAGQGLAINLLKFDNINREIMEVPCAARGPPACVAQSVLLLAFYAVCRTYFLCRWTVYRSCLLSQDTVVPCTIRLFSPRALCTALMFLPGGHSYGSTCPVRVVYLLAFLTTCSRGILRLTRALPAGLAALLQDRFAVLPLRRPLLPQAQPFFQSLLPFSSSPDPGLRFTPFSCSSPSLFGLASSLLSPPPLPLLLVVEALAETVRAIYACSKLGSVPAELDAFPAAAVAHIDANLTKASSARQRALGPSTVSVNAGGAALRNLCLVCIYSGCQQPGRAGGASYQPIKRGIPPGGERSSQGRRAGAAERSKRPQVSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LU24</accession>
    <name>A0A3R7LU24_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative serine proteinase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_017698</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the serpin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003260">
        <property type="protein sequence ID" value="ROT64354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LU24"/>
    <dbReference type="STRING" id="6689.A0A3R7LU24"/>
    <dbReference type="OrthoDB" id="671595at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.39.10:FF:000030">
        <property type="entry name" value="Serpin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.39.10">
        <property type="entry name" value="Alpha-1-antitrypsin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.497.10">
        <property type="entry name" value="Antithrombin, subunit I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023796">
        <property type="entry name" value="Serpin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000215">
        <property type="entry name" value="Serpin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036186">
        <property type="entry name" value="Serpin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042178">
        <property type="entry name" value="Serpin_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042185">
        <property type="entry name" value="Serpin_sf_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461:SF211">
        <property type="entry name" value="GH10112P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11461">
        <property type="entry name" value="SERINE PROTEASE INHIBITOR, SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00079">
        <property type="entry name" value="Serpin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00093">
        <property type="entry name" value="SERPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56574">
        <property type="entry name" value="Serpins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0722">Serine protease inhibitor</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018689332" evidence="9">
        <location>
            <begin position="19"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Serpin" evidence="10">
        <location>
            <begin position="42"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT64354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="306" mass="34385" checksum="12927D52979D9929" modified="2019-04-10" version="1">MRVCVLLPALALLSRASCQCLSSSDTSPPPRLPILKKTTPSASTYSEALPPSGNFFISPFSVWSARPRLLRLPRQHEGGAGAGSAAHQQEDTLALFRALERRYDSQEANQNYTINSANRIYFDQSIPVRECVGKVLDDKVKLIDFNRPDAAAADINAFINAETRGKIPKLIEPSFVKDAKMVLTNAVYFKGFWKYPFKPQRTHKDKFFVTPEESVQVDMMTQTGRFKYVDSEKLHAQVLEMPYRGDAVSMVVLLPMGESQGDRLVRRLRPRRLVSVLKAMPSVPLIVKFPKISVESTLGMNSFRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LV05</accession>
    <name>A0A3R7LV05_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative high mobility group protein 20A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003376">
        <property type="protein sequence ID" value="ROT63795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LV05"/>
    <dbReference type="STRING" id="6689.A0A3R7LV05"/>
    <dbReference type="OrthoDB" id="3213154at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21980">
        <property type="entry name" value="HMG-box_HMG20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051965">
        <property type="entry name" value="ChromReg_NeuronalGeneExpr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46040:SF3">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="400"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="400"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="141"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="271"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="596" mass="66169" checksum="3A7799E7A59FC3C0" modified="2019-04-10" version="1">MEAGGGAGGRVSPLLFGGGLQEPEEEPEETLVLYCGSEEEEEAAGVQRKARVAASLGLDQDFSERDSYGQDPLWLVSNTLQLNIQSEDDVGETVILADSEVVSEGGMLESDALLLLNDSVNFLPISEGLPSSDKLLESINERQPSKMATPVKKYSVKPPSRASHTDYSSRERSKTNFPSRSSPKMYSKGTQGEQAPIVSAVSMTSPTSGAMKEKTLVLGKENATLIKNHQGIGTVVPGATSRTVPKVDSTIILQQEEGVRRDPAMKFKLVDSSKSSVDEDDQYEEPFVGPSLRWPSQPRSYRGAKQRDGGVIRKNVRKIIPGVDTDGETSGMGSSVDEPIESSTESASEAPVVTPSFLQPRPSSSSSRGPSTSPVAVKKRRGGWPKGRKRKPEIPGVKPPKAPLTAYVLFLNERRKYYKETRPELSFGAVTKLLGAEWSSLTPEQKAAFVTRSEQDKRRYRNELQAYRQSHDYQLLLRKKRIKNVIKRGGTTTEESSDFTDEIDDDDSEELYCRICDQLFTSLHNKREHLYGKQHLQVNTNVKGLLKRNVRWQQLECRREGRETASTVAHSLQLMGQVLEQFLRPNNKSRWHQDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LVU4</accession>
    <name>A0A3R7LVU4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021836</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004671">
        <property type="protein sequence ID" value="ROT60635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018525979" evidence="2">
        <location>
            <begin position="18"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1302"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1347" mass="148920" checksum="47F843E4337B04DE" modified="2019-04-10" version="1">MFSIINLLLLLHHYYHSLIFFYSSSPFFLYHYFHSSFSPASFSTTTSPPFLLHQYVFSLHLHIIPSSSSSLPLLSCCPFLHHYISSFLLLRLSILHLYHSSRLLPFLSILHLANSSPPSFLHPSVSSLFCPSSISTIRLSLISPPFSPFLSILHLHHSSPSLISPHYVSSLFCPSSISTIRLLPHFSTITSPPFSVHPPSPPFVSSLISPPLLSPFSVHPISHSSPPSFLYVSPFSVHPPSPPFVSSSFLHHYVSSLFLSILHLTIPSLISPPSPPFSVILHLHHSSPPSFLHHYVSSLFCPSSISAIRLLPHFLTIMSPPFSVHPPSPPFDSSLISTITSPPFSAHLPSPPFVSSLISPPLRLLPFLSILHLPFVSSLISPPLRLLPFLSILHLHHSPPPSFLHHYVSSIFCPSSISTIRLFPHFSTITSPPFSVHSISTIRLLPHFSTITSPPFLSILHLHHSSPSFLHHYVPPFSVHPPSPPFVSSLISPPLRLLHFLSILHLRHSSPPISPPLRLLPFLSILHLHIRLLPHFSTLASPPFFCPSSISPFVSSLISPPLVSSLFCPSSISTIRLLPHFLHHYVSSLFCPSSISTIRLLPHFSTIPPFSVHPPSPPFVSSLISPPLRLLPFLSILHLHHSSLPHFSPLTSPPFLSITSPPFSVSSLFCPSSISAIRLLPHFSTITSPPFSVHPPSPPFVSSLILHHYVSISPPLRLLPFLSILHLHHSSPPSFLHHYVSSIFCPSSISTFVSPHFSTITSPPFSVHPPSPPFVSSLISPPLRLLPFLSHPPSPPFVSSLISPPLRLLPFLSILHLHHSSPPSFLHHYVSSLFCPSSISTIRLPPSFLHHYVSSLFCPSSISTIRLLPHFSTITSPPFSVHPPSPPFVSSPFLHHYVSSFSVHPPSPPFSPPSFLHHYVSSFSVHPPSPPCLLHSPPLRLLPFLSILHLHHSSPPSFLHHTSPPFSVHPPSPPFVSSLISPPLRLLPFLSILHLRHSSPPSFLHHYVSSLFCPSSISTIRLLLISLTSPPISPPLRLLLFCLLHLRHSSPPSFLHHYVSSLFCPSSISTIRLLPHFSTITSPFPVHPHSSPPHFSTISPPFSVHPPSPPFVSSLISPPLRLLHFLSILHLHYSSLPSFLHHYVSIFCPSSISTILPPPPFGRLCLLPFLSILPFVSSLISPPLRLLHFLSILHLRHSSPPSFLHLFSHSISASSPPSFSFPPHFSTLVSPPFSAHPPSPPFVSSLISPPLRLLPFLPILHLRHSSPPSFLHPCVGRPSEDAASNQGQYTISLRCRSEQKFVPDTQQTRKQTNTQTRNRHAATDTHAFCSSDNAVTWPPLPLNECES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZF9</accession>
    <name>A0A3R7LZF9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002637">
        <property type="protein sequence ID" value="ROT68748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZF9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="12636" checksum="6ADC47B96D044D93" modified="2019-04-10" version="1" fragment="single">MDGDGNGASGKDRDERDESGEKQDNLRVTKTGRVRKRRRRRGRKASQPVEEAVPPIKGWCLKRYPGLNQRAPFPQVPTRRGRSELEAEGLAPAREASDFDQYGGYRRTRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5A3</accession>
    <name>A0A3R7M5A3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cuticle protein AMP3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_009264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002170">
        <property type="protein sequence ID" value="ROT72354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5A3"/>
    <dbReference type="OrthoDB" id="6359117at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062129">
        <property type="term" value="C:chitin-based extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008010">
        <property type="term" value="F:structural constituent of chitin-based larval cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031311">
        <property type="entry name" value="CHIT_BIND_RR_consensus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050468">
        <property type="entry name" value="Cuticle_Struct_Prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380">
        <property type="entry name" value="CUTICLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10380:SF237">
        <property type="entry name" value="CUTICULAR PROTEIN 65AU, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00947">
        <property type="entry name" value="CUTICLE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00233">
        <property type="entry name" value="CHIT_BIND_RR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0193">Cuticle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018761142" evidence="4">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT72354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="131" mass="14505" checksum="8EF0BD1CF5555E45" modified="2019-04-10" version="1">MHLILLVCLAGLVAASPMPQNRHPEYDAQILVDEREDRGDGNFRYRFETSNGINTEKVGTPGSQGQSNMQGAFSFPLPEGGVAQFTYVADEFGYQPSSDLLPQPPPLPAHVYRLLEIAEQQRAQGITFEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5K7</accession>
    <name>A0A3R7M5K7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Adapter molecule Crk</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_014157</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5K7"/>
    <dbReference type="STRING" id="6689.A0A3R7M5K7"/>
    <dbReference type="OrthoDB" id="9204160at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030971">
        <property type="term" value="F:receptor tyrosine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007167">
        <property type="term" value="P:enzyme-linked receptor protein signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09926">
        <property type="entry name" value="SH2_CRK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11758">
        <property type="entry name" value="SH3_CRK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035457">
        <property type="entry name" value="CRK_SH3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051184">
        <property type="entry name" value="Tyrosine-phos_adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19969:SF5">
        <property type="entry name" value="CRK-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19969">
        <property type="entry name" value="SH2-SH3 ADAPTOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00017">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00401">
        <property type="entry name" value="SH2DOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00252">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH2" evidence="6">
        <location>
            <begin position="59"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="153"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="237"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT67764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="35096" checksum="0DDE7839B67613D2" modified="2019-04-10" version="1">MVDSEIPAEREREEGGVGREKSRKRMHDIYATRAGRKPEQRNEHPNKGGSNKGGVAEHWYFGQMSRQDATDLLMSERDGGVFLVRDSTTILGDYVLCVREDNKVSHYIINKIQQGDQMRYRIGDQMFPDLPSLLNFYKLHYLDSTPLIRPAPKRCEKFVAKYDFEGSDPDDLPFRKGEVLTIVSKDEEQWWTARNSMGQTGSIPVPYVQKYEEGESIAINLTANRSSTQSTDSTQRAKPSLQRKLPAYEKQNAYDKTALRLEVGDVIKVTKMNINGQWEGELNGKVGHFPFTHVEFIDSENSVDGDPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MC07</accession>
    <name>A0A3R7MC07_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001472">
        <property type="protein sequence ID" value="ROT77807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MC07"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="488" mass="52928" checksum="7846128ABE45E5F3" modified="2019-04-10" version="1">MTHLTRGASYAPLTRLCQLLSLQAKGISPSLTFHPPPTHSLSIYTFLFAFPVLFPSPPFLFSFPLPPLLLPSTPSNSLPFFPHSTLSPFPISTSLFSLSLSIPTLNFSSSLSSPFLTSNFPSSLSLPHSLPLNFPLLSLSLPIPYLSTSFFSFSLPIPYLSNSLFSLSLSPFTTSQLPSSLSLSLYPFPTSQLPLFSSLSLSPFPNLLTPSSLLLPIPYLNFPLSLSLSPLPTSNFPLSLSLSLSLPIPYLTTSYPFSLSFHFSLPVNPSSTALCHPSLPFNYVRDTSLTLSIIPHILPSPNTAIACFLSPTNTLPSFCMSLVISLFLSTSETLHHLSPTLSSYFKRSLYCPPSSQRSHISTLHPLSQRPPPLLSPTLLITPFSLQRPHTPFLSPNAPHNSLLSPTPVTPSVLAPHTSLSLSNALYTSFFSLYNAPPTSPHLSPTPLIPPLLSPTPLLFLPLTLNAPHTPPPSLSNAPHTFLPLQRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHY3</accession>
    <name>A0A3R7MHY3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001576">
        <property type="protein sequence ID" value="ROT77025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHY3"/>
    <dbReference type="STRING" id="6689.A0A3R7MHY3"/>
    <dbReference type="OrthoDB" id="9983043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20541">
        <property type="entry name" value="CYCLIN_CNTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21615">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21615:SF2">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="335" mass="37493" checksum="9E2BDD727C0CA8B3" modified="2019-04-10" version="1">MDNAIFHVPVIDQFNSSGKYWTKQDVDPIAGYLEDWLKREIADNDLLKHDFQPHLTAMSLRAPVRVLWMAAEELGLSAPTKYRALEIFNRFIKGHAATLAGHVTSTTNPGRERNRLLAEVARRVRQQAPLRAFTCLMIASKTVSHKKVLRAQQVQALLKKVGRDYTVSSIMSSERRILEQIEFRCLRTSSVLDLVGLIVAVVLVSKSTDGKHVPFKSEQLYEAAATVLDFVFLKHEEVYLQLYASVTDSKIIPRKHKAAFLPVVEDRLLLAGSVVVSGAWLVGGEELVESAGGRIARHTETPLEDLVSLASCILYLAGAMEPQKQMTIEVRDFMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIC9</accession>
    <name>A0A3R7MIC9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 18">DNA topoisomerase 2</fullName>
            <ecNumber evidence="7 18">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">C7M84_004026</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="22 23" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="22">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17 18">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 18">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="7 18"/>
    <dbReference type="EMBL" id="QCYY01001538">
        <property type="protein sequence ID" value="ROT77325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MIC9"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.268.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000003">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.30:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000008">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000004">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14 17 18" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="15 17 18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 17 18" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="20">
        <location>
            <begin position="457"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="21">
        <location>
            <begin position="717"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1174"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1174"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1218"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="1289"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="1307"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="1461"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="1485"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="1508"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="17">
        <location>
            <position position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ROT77325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1579" mass="178930" checksum="E9C7801341A717D3" modified="2019-04-10" version="1">MPAVNGTDVPNNIPAPAMVVQQAAKKGPKSVETVYQKKTQLEHILLRPDTYIGSVEYTTEQMWIFDPETDRIVQKEISFVPGLYKIYDEILVNAADNKQRDPGMDTIKVEIDPENNVISVYNNGKGIPVAMHKEEKMYVPTMIFGHLLTSSNYNDDEQKVTGGRNGYGAKLCNIFSNKFVVETASKEYKKNFKQTWGTNMSKTSDAKIKDYGGEDFTKITFSPDLVKFKMESLDKDIVSLMSRRAYDIAASTKGVKVYLNGKRVPVKNFKDYVDLYLKDKVDDADNPVKPVYENVNERWEVAVALSDKGFQQMSFVNSIATTKGGRHIDYVTDMIVKNLTETLKKKNKSGVQIKPFQIKNHMWIFVNCLIVNPTFDSQTKENMTLQAKSFGSKCSLSDKFINNVMKCGIVEAVMTWARFKQQAQLQSKCANRKQNKLKGIPKLEDANDAGTKFSSDCTLILTEGDSAKALAVAGLGVVGRDRYGVFPLRGKLLNVREASHSKILENAEINNIIKILGLQYKKKYDSSEDLKSLRYGKLMIMTDQDQDGSHIKGLLINFIHHNWPTLLRHTFMEEFITPIVKATKGKEELSFYSLPEFEEWKKNKDNWPSYKIKYYKGLGTSTSKEAKEYFNDMVRHRIRFNYGGAQDDHSIQMAFSKKAIEQRKEWLTGWMEECKRRKELGLPEVYLYERDTRAISYTDFVNKELVLFSNLDNERSIPCLVDGLKPGQRKVLFTCLKRNDKREVKVAQLAGSVAEHSAYHHGEASLMSTIINLAQNYIGSNNINLLQPIGQFGTRLQGGKDHASPRYIFTMLSKLARYIFHPHDDPLLKSNFDDNQRIEPEWYMPILPMVLVNGAEGIGTGWSTRIHNYNPREIVENLKRMLRGEEPTRMDFRGTVEELDSQRCIVHGEIANLGGNKIEITELPVRVWTQAYKETVLEGMLASTEKSPAMITDYKEYHTDTTVRFTVTISEAKLGKAMEEGLHKTFKLTSSLSTNSMVLFDHNGVLRKFEAVEEILREFFDLRLKYYSKRKQYLVGMIQAEASKLSNQARFILEKCDGRLVIENKKKKDMIAELQRKGFDSDPVKAWKRVQDREAALEEEEMQSESDREEVDLKGPDYDYLLGMAMWSLTKERKDELLKKRDEKNQELEELKKKTPDNLWLNDLDEFLNKLDEVEREERESEEAANKKSSAGTKKVKKLKNETMPSPFGERVVPIIDPEMKKKAEKAAAAKESKGKRVKKEVVENDDFDDLVAANTGKSLAARLGNSPDLIMKKAKAKKGDGMKQTKLNFKKGSPKKKKGKNPWESGSEDDDDEDDIDADDVQPRERAAGRRTAAAKIKFQFSEDEESDSNESLHDNAGVEEIDSGPQQMSMLDDSIAQVEPKNEVVISDTDSEFDVKPKKATVAPAPVQDKPTASDLFDSMMGSSSPPKYESEPIIAKKAPAKKRTKGDSSSEDDSVPQPKKKPGPKKKATVVPDDMSDDEPKPKKKGRPKKKATGDNDMSDDEPKPKKKPGPKKTAAAKKKNDSDSDDMFDDIAPKGKAALNVSDDFNISDVVPRERSGRQKKVITYALSDDEDSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIH2</accession>
    <name>A0A3R7MIH2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003939</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001527">
        <property type="protein sequence ID" value="ROT77414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIH2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="625" mass="71092" checksum="EA560E6018F6E00D" modified="2019-04-10" version="1">MLLQHDLWCSHCLTISLYDTPKWLTVASFSLRSSFHCLPFPPKFRPNFAQPNGMRGGSCGVAGERSHGAWPRGGRTTPRRGRRGSREAAPPEGARREEEALILTEASKAVFRVAACLGLYVVAREGENCYRISKLKIIPAAISFVAALSSLLHAILLMFFTEMTYDQEILFLPLFSGSCFCFYIYILWMRKSHWIMDYMTQLEVHAIKIPKRENMPFVIAGVFIYSASYAAAAAVALPVPSFISSGSLRYLLFIPVFFTAFIPSFADIWVFSFLHPLVVALQGLTRRARDVKVWTKEVSASVMKEWLLLHRLLEIYNERPIPYFLGREYISFPESLFPFSLTESYPFPFMPASFPGSPTRIHPTSLFPFMEANFPVLFPKWKNSSNECMLTFWELSHMTPTGCPAWCSPLQGLWVSLFWEVFSYMIHVRFLVFIVQALTISFALAALRWQSKCLAYLPLLLVSLLERDNVVAAVRERLCRPPSHSAKEDAETTLKILHNTAVRITTEGDEESEAEEEHKTTSGRCSVFTTSFPTWRLDLLLLRSGGEAYDLPEVTCALPSRPASRSRLLPFSLCTRKYMRCLGVVVTYLVILLQLRPQNQKGAEDEEDLGIVQCFDSIKPFHRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIT8</accession>
    <name>A0A3R7MIT8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019348</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003552">
        <property type="protein sequence ID" value="ROT62789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIT8"/>
    <dbReference type="OrthoDB" id="10071059at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018743110" evidence="3">
        <location>
            <begin position="18"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="535"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="63488" checksum="E035E9543E56C90B" modified="2019-04-10" version="1">MWKKVLVALAAVLAVDALKVEEAEVQRVPRQSGGYAYQQPVGGQAALGGAGGQAALGSGTGGATGGQAALGSGVGGATGGQDALGSGVGGATGGQAALGAGAAAAAGAGAGAAAGAGAAAAAGAGAAAAAGAGAGAFGGQAALGAGGQAALGAGGAVTPWPPLMPYQFAYEVKDDASTNYHNRVEFVENGVLQGSFSLLSPDGVVRTYIYSDDGSSGFKVTSHQIPTDIVVVGSGLPGDPKAAGGAGASAGASASASASAGASGGAGAAGAASAASASGSAGFGAGGAAAGASGSAGFGTGGAGGAAGAAAGSAGFGAGGASAGAAGSAGFGAGGASAGATGSAGFGAGGASAGAAGSAGFGAGGASAGAAGSAGFGAGGASAGAAGSAGFGAGGASAGAAGSAGFGAGGPAGAAGSAGFGAGGASAGAAGSAGFGAGGAAGAAGSAGFGPEHQLDQQVWSLEVQLDQQDLEPEVQLDQQVLEPEEHQLVQLDQQVSEPVELEVQLDQQDLEPEVQLDQQVLEPEEHQLVHQQDLELVEQQVQLDQQDLELVEHQLVQLDQQDLELAEQQVQLVQQVLELVEHQLDQQDLELVEHQLVQLDQQVSELVELEQQVLELEPHYSQALVQAQLVLLGHLVAVPLYLWYIQISLEELVQPIQQQAHSASQVLLLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MK82</accession>
    <name>A0A3R7MK82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA-binding domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_002376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001315">
        <property type="protein sequence ID" value="ROT78915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MK82"/>
    <dbReference type="STRING" id="6689.A0A3R7MK82"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF77">
        <property type="entry name" value="LD25952P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="ACB" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT78915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="48589" checksum="E2218785F131C179" modified="2019-04-10" version="1">MMLKFYALYKQAVEGPCNEPKPAFYEVVRGYKWRAWNSLGNMSKVEAMSTYVEELKKIIETMAYTEDVANFIDALGPFYEFIDIPGAKNKNNNNNKGNDKPNNDKKDDPDGDANDKPITNGLNLPDKMNGIHNLDSDSGSGSEAAQSSSQDSSPQHSREETMSQEVREDDEILEDEEELVVVEVRTEREDKTTHTLSLSPRVLSDTDSDEEYSEPAETPDHLAKVQSLLADQGLTPPRRFHQLENQESTSYPATAPALLSQHVPVSNTSIDDAVTCGGGDQSHPGGLQMTPRQSQQRFSGTPLYTSQVSSGSLATPIHSGGFIRGSGGGGSGGDGGRGGGTDIVEDVNAQLVVVLRRLQADMESVLHRLNTLETITLSQHHTVCHHCQTGSSNTPTTRMEPSWWPFPELSPRSTFFLLVWPLILHGGIKLLLLLRSRRRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MM95</accession>
    <name>A0A3R7MM95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative zinc transporter 6-A-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_016649</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory pathway. As part of that zinc ion:proton antiporter, contributes to zinc ion homeostasis within the early secretory pathway and regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterodimer with SLC30A5; form a functional zinc ion transmembrane transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003092">
        <property type="protein sequence ID" value="ROT65384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MM95"/>
    <dbReference type="STRING" id="6689.A0A3R7MM95"/>
    <dbReference type="OrthoDB" id="6353494at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052005">
        <property type="entry name" value="CDF_SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46531">
        <property type="entry name" value="ZINC TRANSPORTER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46531:SF1">
        <property type="entry name" value="ZINC TRANSPORTER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="273"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="14">
        <location>
            <begin position="81"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT65384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="580" mass="63990" checksum="48BA09B2DEADF889" modified="2019-04-10" version="1">MSTSITLQEDIKNARIPGTSYISGNGVRQRANNADCDEEAPHYFIRPFKEGAASLSSLQSFLQELVWLFNQREAQQTLGLVAVNLLATLLLLSWCHATRSMALMAYTYLSWFSLLSLVTCLVCVWAESQKATPTFTFGYRRCEALAVFASVTLSLLGAVIIVKECIERLLEPEEVHTGMLCMGGIVGLLLHLGMTVLAHNPPLTQVLRASQSSLLQEHVADMCQSLCNYVPALSRVLLPRVNPVVLISIAGFLAIIGDNIILEIYNYQAADSIAALVIAILTITTMFPLCVCSASILLQTTPVSVFAQLDKCLREALTLDGVLEFRHENIWTLGLSDPSRGSLSALGDHSGFILTGSLHVRIRRDANEQMVLAHVRERLAPLVPLLTVQVFKDDWTRSSTTLQLLNDSSRALASSPSHSPHYVNVTYPHIYPSAKSSGGRSPFFPHNSPIGPISTYSPSTLSQGILGYSHSTPTLSSSSSEHYDHGAHRNFPKERMALQNNLSDDTHRLGSAMHREATYLSSPGLDESQGKVQGSRDREPRWRPSLALDLLLGVRLRLLDKFLRRYRYHYGDVTHGLSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MMF6</accession>
    <name>A0A3R7MMF6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_010177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000229">
        <property type="protein sequence ID" value="ROT85620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MMF6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="43013" checksum="24A26266B9106490" modified="2019-04-10" version="1" fragment="single">FYFFYHTFNQLLLILLYSYPDSFSSRLHSFSHSFSPRSLTRSHSFSYSFSYSFSHSSPHSFSHSFSYSFSYSFSTRLSYSFLSSFSRSFSPRSLASFSPRSLLILSSFIPLILSSSLARPRSLLSPRSPAHSLLVLSLILSLSRSFSPRSLAHSLLVLSLIPSSFSRSFSPRSLVHSLLVLSLILSCFSRSFSPRSLVHSLLVLSLILSSFSRSFSLLVLSLILSSFSRSFPPRSLVHSLLVLSSFSRSFSPRSLAHSLLALAHPSRSLGFFSSFSRSFSPHYLLVLSLILSSFSPRSLAHSLLVLSPILSSFSRSFSAHLSRFSRSFLLVLSSFSRSFLFSLVILSRSLLILSSFSRSFSPRSLAHSLLVLSLILSSFSRSFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MR21</accession>
    <name>A0A3R7MR21_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycine N-acyltransferase-like protein 3-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002763">
        <property type="protein sequence ID" value="ROT67753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MR21"/>
    <dbReference type="OrthoDB" id="6340235at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053225">
        <property type="entry name" value="Acyl-CoA_N-acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="GCN5-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20958:SF6">
        <property type="entry name" value="GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCN5-related N-acetyltransferase Rv2170-like" evidence="1">
        <location>
            <begin position="211"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="298" mass="34028" checksum="DC30A24D727D0239" modified="2019-04-10" version="1">MEDEEVFVRVEDQGRLMKISKVIREELPFSASMHNCLVLHARGFASSQDFYELRTPTNSLIILSRSKGEQDTVTLFCCEDDVGLLMEGLEKTRLIDWTKPFFFLHLPVYMAEGIRALVESRAEGQGDFQFVETFLYSKEDDEEGLLCPAGMRVCHLGERGVRQLHAAWQYNKYVDVSKFLSLARHPTNVGVYESDVGEVHRVEPTCLQRAGDEESAVAWVALTFYGTTGMLYTVESHRRRGLARLALRAFSRLQDKQGLIPHAFVEDYNDSSRRLFSQLPGWRSVTRTLIVGVKIDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MRP2</accession>
    <name>A0A3R7MRP2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013751</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002717">
        <property type="protein sequence ID" value="ROT68122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MRP2"/>
    <dbReference type="OrthoDB" id="6884957at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="327" mass="36563" checksum="54496EB938FBE1BE" modified="2019-04-10" version="1">MLQSLFVVPLIPAASLRHKHVLSSRDRARTSGSTVLHYRTAEAALKPRRQRLGASVARVPAWSAKLPPLLDLPKPKSRKTADVMAFTDFDSIFDHIGGFGRYQMMLFWINCLMNTFLVFVYFGQFFMTLTPPHWCAPPPDLAGLNLTSDQVKSLTIPRDPHTAEVPGVRQYHPGDTLSSKYRTIMANVPIMIFLTVCHVVLLPWLAVALGPMEGSSPSPSYLPQSCRVSLLYVMYLYRFVSLGSYIIISHSLSTVFLFFFLLSPSLALSLSHLRLSDPLLRGQHRRHAICSLSISLSLTHLLESHTSLLRSLFPLSLTSSIFPISIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MYC7</accession>
    <name>A0A3R7MYC7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acyl-CoA synthetase family member 3, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_008989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MYC7"/>
    <dbReference type="STRING" id="6689.A0A3R7MYC7"/>
    <dbReference type="OrthoDB" id="2962993at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05941">
        <property type="entry name" value="MCS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000030">
        <property type="entry name" value="Acyl-CoA synthetase family member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF8">
        <property type="entry name" value="ACYL-COA SYNTHETASE FAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="5">
        <location>
            <begin position="464"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="557" mass="62431" checksum="399726DB808A9722" modified="2019-04-10" version="1">MRSVVPVFRRAEQYHDNVALTDQHGEHTYSQIYRFSGHLARLMQDVLGRDRVQERVAFLCPNDVSYVIAQWGTWMAGHIAVPLCPKHPHPQLEYVVKDSQASAIITTSDLAHKIKPILSGQQVIVLEEYFYKQSPVSKENEDSPDASPESIGDESSTAQWYGLDNEFYSLSDAMILYTSGTTGPPKGVVLSHKNVASQTSCLIQAWRWTSSDSILHCLPLHHTHGIVNALLCPLHVGARVVMLPEFSASKVWSHLLSLDTPVMSRVNLFMAVPTIYAKLIEEYEDKLVKNTRMIEYVKAVCMQNIRLMVSGSAALPVPILDRWKAITGHTLLERYGMTEIGMALSNPLKGTRIPGCVGTPLPGVEVRIAKFIPGKEEYEVLCAGNNQGTKVFTDGEAGELLVRGPNVFKEYWNKPEATKKEFTHDKWFRTGDTAQYIDGAYKILGRTSVDIIKSGGFKISALDVEQHLLDHPHITEVAVVGLPDITWGQKVAAVIVWQKKEPLDLVKLRNWARERMPHYQVPSVAITISEPLPRNNMGKVNKKQIVMDFFPDSMNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NQN2</accession>
    <name>A0A3R7NQN2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003304">
        <property type="protein sequence ID" value="ROT64194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NQN2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039877">
        <property type="entry name" value="TMEM131-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22050">
        <property type="entry name" value="RW1 PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22050:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 131 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="57563" checksum="F0ED7298924D65FF" modified="2019-04-10" version="1">MTGGNTFGFFVSSFLLLSSSFSFSSSFSFFLLFFLLFFLLFLLFLLFSPFPPLLSLFFSLFLLLCFLLFFLLFLLFLLLFFLLLFFRLSSPSSFSFLPPPPLVFYFFSTCFPFLPSPSFFLVYLPLYPPSAPFLLPSSASLSFPSFRISFILPHPFSPLGFLSLPIIPSPLLLPISPSLLLSPLLSVPFSPCLSKSPFPSPADPPPLAHLSFHSSPSPFFSVYLPLSIAPSLLLLSFSSLTFPSPSLLPIILHSLFPLYSYPSPYFPPFLSHPFLLLYSYPFPSLPPFLSPLFLPPSHLYSYPSHLSLLPPLSPPTFPSILTPYAANNHHHHHPPTTTTTNNNSHLDQPQTTHHHHNPPPPPPNKQRTKTNHHLQQPQTTTTTITTTSPTHPSHNTTTTQQQQPPTHHQPPTTTPQSHQTHTTHKSPHTTTNHNHHHTNNNNQAMTTHHQPATTTHHTTTHLKPTNNNPTTTHNQQSPTTTNKQPQITTTNKQPQITTQRTKTTTTITTTQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRK8</accession>
    <name>A0A3R7NRK8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Metalloendopeptidase</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_017219</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01003177">
        <property type="protein sequence ID" value="ROT64837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRK8"/>
    <dbReference type="STRING" id="6689.A0A3R7NRK8"/>
    <dbReference type="OrthoDB" id="6360618at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="12">
        <location>
            <begin position="18"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="11">
        <location>
            <begin position="226"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="365"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="445" mass="48996" checksum="8C97EA5709341C18" modified="2019-04-10" version="1">MLTPEQQAILHGRKASSNLTAYWSDDGGFPLIPFAFYDAYVNRYKVWMAILEWEQATCIDFVEVSTGYSGPHLKIQRHADDCRSFIGMVSTTGQDFYISEDCEGQHGELLHLLGYAIGFWPEETRSDRNHYVQINNDNVLATVVDNFPLNSDNNYSVPFDYCSIMFHHERAFTNNGGITIATLDPLYQGVLGQRSQMSHMDKLLANTMYQCADKLLSKCSLGSDPCSNSGYLDKSCSCICPDGTSGTYCDTVTSAYGEIKFTKVIKAPECYLVRASFTSFSIYQKTNHYVTDSTLLNICWYDGLEIRTDDMYDGSWYCGTELNGQNVTSTSNEMILYFKSKLNYMPGWTANIAFIEDPACITSTSSTSTSTATSTSTTTPSSGVPSPRLSAAIASGTEYRLPSLLFLATFSSDGSLASSGFSLSFQLSSTGCHKVRGGGKLPSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NS93</accession>
    <name>A0A3R7NS93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003086">
        <property type="protein sequence ID" value="ROT65415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45598:SF1">
        <property type="entry name" value="4FE-4S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45598">
        <property type="entry name" value="PROTEIN CBG11839-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1466" mass="160986" checksum="65D2DA9B68D79F37" modified="2019-04-10" version="1">MRRGTWACTRMHTHSARTPERTCTLAHVLEAYAPLSSLSLSPSRLRYSRDGTFHPLSPLSSLPLVFAIPEMAHFTSLSSSPSLSLSLSLSSSLFPEMAHFTLSLSPPPSSPLPPSSLFRDGNIYPLSLPSPSPSPSPLLSVFAIPRDGTFHPLSLPLPLPPSRLRYSRDGTFHPLSLPLPLLIPLLLSPLPLALLVFAIPEMAHFTLSLSLSLSPLPLLSLRYSRDGTFHLSLSSLLPLPLPLPLSLSFSLFRDGTFHPLSPPSPSPSPLPLHGTFHPPLSPSPSLPLPLPSSSLFPEMAHFNLSLSPSPSSLLSPLVFAIPEMAHFTLSLSLSLSPSPSPSRLRYSRDGTFHPLSLPLPLPPLSSSLFPRWHIFHPLSLPLPLPLSLVFAIPEMAHFTLSLSLSPPSLSLSSSAIPEMAHFTPSLSPSPSPLPSLRLAIPRWHISPSLSPSPSPSRLRYSRDGTFHPLSLPLPLFSSLVFAIPEMAHFTLSLSLSSSSPSSLFPRWHISPSLSPSPLSPLLVSRLRYSRDGTFHLFFSPLSSLPLVFAIPEMAHFTLSLSLSLSLSLPLSLRLRYFPEMAHFHPLSPLLSSLSRLRYSRDGTLFPSLSPSSSLSPLFSRPIPEMAHFTPLSLLLSLSRLRYSRDGTFHLSLSSPSLLSLSSLRYSRDGTFHPLSLPLLSLSSRLRYSEMAHFTLSLSPLSLSLLSVFAIPEMAHFTLSLSLSSLPPVFAIPEMAHFTLSLSSLPLSPLRLRYPRWHISTLSLSLLSSLLSPSRFFAIPRWHISPSLSPLLSLPPRLRLFPRWHTFHPLSLPLLSPLRLRYSRDGTFHTLSSPLSLSPLSLPLVFAIPRWHIFTLSLSPSPSLPLMAHFTLSLSLSSLSSLFAIPEMAHFTSLSPSPSPSSVFAIPEMAHFTLSLSLTSFLLSLSLPVFAIPEMAHFTLLSLSLSPPVFAIPRWHFTPPSLSLSSLSPPVFAIPEMAHFTLSLLPLPSLSLSSSLFPRWHISPSLSPSLLLSLSSRPSLFPRWPFHPLSLPLPLSLLSLSSRYSRDGTFSLSPLPLPLSSLRYSRDGTFHPLSLPLPLSLPVFAIPRWHISPSLSPSPLSLPSSLFPSHPEMAHFTLSLFPLPLSLPSSAIPEMAHFTLSLSLSLSPSRLRYPRWHISPSLSLPLPLPLVFAIPRWQHFTLSLSLSPLSLLFWPFPPLSPLLSLVFAIPEMAHFTLSLSLSLSLPSSLFPRWHISPSLSLSLSPSPLVFAIPEMAHFTLSLSLSLSPPVFAIPRWHISPSLSLPLPSPSSSSLFPRWHISPFSLPLPPPPVFAIPEMAHFTLSLSLSLSPSRLRYSRDGTFHPLSLPLPLPPMAHFTLSLSPSPLSLSSSLFPRWHISPSLSLPLPLSSLPFPRSHFTLSRLAIPEMAHFTLSLSPPSLPLGRPLPRVLPVKYQILPYVGQEIFPNVAEFPDIKRQPRRNNKPGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5J3</accession>
    <name>A0A3R7P5J3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001698">
        <property type="protein sequence ID" value="ROT76045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5J3"/>
    <dbReference type="STRING" id="6689.A0A3R7P5J3"/>
    <dbReference type="OrthoDB" id="10055432at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41153">
        <property type="entry name" value="RE41427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41153:SF2">
        <property type="entry name" value="RE41427P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="42564" checksum="FEC4163FCF281BA8" modified="2019-04-10" version="1">MIRQASEVSDLASEAEDCLVGRKIQEEKWEASLLWLSLSLFCFGLLSLHERCHFYHSGLLPLSAGNAVWGEDWTGADPVTTPPPDRSYSSAFANNRAMMASSRASGNAGGRSVPGARYEVESLLSVDLWPGLSVTLMVLWAAVCGCGLVGAAKYAWGDALTDPDALGPDGMKYPTKLINRLYADGEFGPPSGMRRGRTLMKTLDPATVRENLMQGFYDANAHNDHATLRPQGRSMPDRDSSPSSPARAVASSVQENLVRMSTSVKSSTSTSTMSSSSSSSSTACPKGPPARMCQTRYNTTAPMYGVSLTSGQPVTIVQKFPDLLQQVIFEVCESDTCDVVQGSCVQTYVPYLFLVIPLGPVTLTGQDYVLVESGCVCQPKYSQASSLPSPIEAISGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P749</accession>
    <name>A0A3R7P749_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_019345</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003551">
        <property type="protein sequence ID" value="ROT62792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P749"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.400.10:FF:000030">
        <property type="entry name" value="Sortilin related receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050685">
        <property type="entry name" value="LDLR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270:SF8">
        <property type="entry name" value="LD11117P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="6" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="517"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="548"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="605"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT62792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="643" mass="72184" checksum="F3D08B9629D6110C" modified="2019-04-10" version="1">MSLVSFIIVNSFLFILFSFSVRCLPLFLFPCEAGYFTSYSPSLFPVTFCLSSHPFLPFLPVFLLSLLPFLFPLPSLPSDLPFLPTPSMSLSLPLFPLYPSSLTPSLPLPHSLSPFPLSPFPPLFSSFLPSPPSIPLPQTLSPSLPLTTRPAPRRALPRPSARVLSFFPIPSFIALSRSFPFLPLLPSLVLSPSPVTATLILSSSLHCCLLSFFPFPSFIALSRSFPFPPLLPSLVLSLSFLYCPLSFFPIPSFIALSHSFPFPPLLPSLFLSLSFLYCPLSFFPFPSFIALSHSFPFPPLLPSLVLSLSFLYCRLSFFLFPSFISSFFSFPSFIAVSRSFPFLPLLPSLILSLSFLYCPLSFFPIPSFIASLSFPFPPLLPSSFFPFLLYCPLSFFPFPSFIALSHSFPFPPLLPSLVLSLSFLYCRLSFFLFPSFIAVSRSFPFPPLLPSLVLSLSFLYCRLSFFPIPSFIALSHSFSFSRDGHSHSFLFLYCRLSFFPIPSFIALSHSFSFSRDGHSHSFLFLCCLLSFFPIPSFKKSCKQNEFQCRDGKCIPHRWQCDGDGDCDDKSDEDSQYCEEVTKCTGVSSEHWLCGSGECIPLAWHCDEDWDCKDGSDELNCPSKLISAMLVLRQFFISRKFYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PCQ4</accession>
    <name>A0A3R7PCQ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative calcium/calmodulin-dependent protein kinase type 1 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002881">
        <property type="protein sequence ID" value="ROT66838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PCQ4"/>
    <dbReference type="STRING" id="6689.A0A3R7PCQ4"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000026">
        <property type="entry name" value="Calcium/calmodulin-dependent protein kinase type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="251"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="283" mass="31936" checksum="E6AA75A605663DA5" modified="2019-04-10" version="1" fragment="single">LTHPNIVQLLETFEDKHKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQVLEAVDYMHDQGVVHRDLKPENLLYYSQDEDSKIMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVIAYILLCGYPPFYDENDANLFAQILKGEFEFDSPYWDEISDSAKDFIRQLMCVDVEKRYTCKQSLGHPWISGNAASDKNIHSSVSEQLKKNFAKSRWRQAYHATAVIRQMRLLALSTQREKKLSESSDTNANTTTTSAPPASKSPRENAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEL7</accession>
    <name>A0A3R7PEL7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003452">
        <property type="protein sequence ID" value="ROT63317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEL7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="41999" checksum="1BFE023F203EE13B" modified="2019-04-10" version="1">MAQQARRCRAGAGALARACSLGEMDGDSLRQPLLASGANGRSETPHSPRAERHDRPLEPDAERTRSDSPHRTKPVPKRLPRSRRRGCTSFLSLEIRDALHLPTIAITRSQRSRAGSEVGAGWTPLKWHSLGCERDLTRRRHSHIGFNIPLLQAFLTPTAHTRNSVTNSPPYNFSVCLLGSISILSAGWDSCDSDIEYIHGKTQATLSRARSVRDVCWGIPWLSTDCHISTTLLPRSLHPPQPYIFPRSLHSFQPSILHRSFHPSLLPSTPSNPASSLATSSPILHPPSTLPSSLTLHPPSLPPSSLNPSIPYNPLFSLAPSILPRSPQPSILLIPGAHHLALPLKSAKPPLRPFPPGRHLPTVIKTNDVRYHHALCLSFRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PES1</accession>
    <name>A0A3R7PES1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Centaurin-alpha 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_013016</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002630">
        <property type="protein sequence ID" value="ROT68815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PES1"/>
    <dbReference type="STRING" id="6689.A0A3R7PES1"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902936">
        <property type="term" value="F:phosphatidylinositol bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005547">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08832">
        <property type="entry name" value="ArfGap_ADAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13252">
        <property type="entry name" value="PH1_ADAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01251">
        <property type="entry name" value="PH2_ADAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000011">
        <property type="entry name" value="Arf-GAP with dual PH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000080">
        <property type="entry name" value="Arf-GAP with dual PH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000099">
        <property type="entry name" value="Arf-GAP with dual PH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052589">
        <property type="entry name" value="Arf-GAP_dual-PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037849">
        <property type="entry name" value="PH1_ADAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037851">
        <property type="entry name" value="PH2_ADAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46021:SF2">
        <property type="entry name" value="ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46021">
        <property type="entry name" value="ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="11">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="129"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="10">
        <location>
            <begin position="250"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT68815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="44630" checksum="34B97ABA29986B26" modified="2019-04-10" version="1">MTDRNSRRIADLVKLSGNSECADCGYQPPEWASYNIGVFLCTTCAAWHRRLGSHISKVKSLTLDKWDDEQVEMMETIGNVSAKEKYEQHVPACYRIPRAGDPSVLLEQWIRAKYERQEFIEVDKQTYIRSYLEGTLMKRARDENKYFPRKFVLADNTLKYFSKENAKEPKATINLSELNVCLAPSKMNQENGLQLSYMCEGSTRHIYVYHESGETIIHWYTAIRSIKLNWLMVAYPSASAEELVPYLTTDFVIEGWLSKTGPSERDAYRKRWFILDDRKLMYHEGPMDAYPRGEIFLGHKDDNYSIKEGAPRGCKDQDFSFSLTTPERTYVMSAPTSDERARWIQAINTVLERVLRPQDNQSKMAISENRKSARNSRHSWLSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PEU9</accession>
    <name>A0A3R7PEU9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_012882</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002617">
        <property type="protein sequence ID" value="ROT68953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PEU9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="628" mass="68488" checksum="6C4067E9294F0F8D" modified="2019-04-10" version="1">MNCDEIVLCGGEGVGYPLHPLKKTFVRSVDDIDFDIIAEANLLTCGCAEGYTEIRDETTHHLPTCQKGGGGWRRPGQRGLAAAVCPVAYIDGITGIVRCVCNPATQVSLFEVVDSVTRGGLTTDYDMDTVQALTVFKDELLDGLDACLPKPGVDPRVSAFGYGFAAHVFYDDDNDEASSFRLGDNMGGHLMTGGLVRRGGVTSGGDWLSAVDDDRENENKRASYSIGGISPFLGTGGVPAHIWGGDVWNDNNIIVGSSPDKDRIAIVHPNGSLKMVPPSTTGIPGVGVSLEHAVGLVASAGRYYPGGVYRRGGELSTKDCGVNRESCFLEKVTDMDKNNPLTQMMSTNDPGVCASAFIVPFFHDKCRTDYEKNPEAARLPREAPTQRLKGLTGHYHSRPLAMAMGYTPIERLFRYFCSTCTRRKNLAFPDKFISMFPHMIQGNVSTEDDWQRLFSSTGQREGDNNEFSVDLLGGLFIQPTTVSGSGTSSLNTKWTEEMISTNLPCLIDHYEIDDGRAYSVGVDHDDENSKVKYVRYPTAQNLVANQTGQYTGFSLTGGKENSGYSHTRESPYCFVDAAVFGAENVIWNNAGFTTLALPQDVPLPFFRGDEILQTERFFRLDEGVVGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIS4</accession>
    <name>A0A3R7PIS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_014010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002740">
        <property type="protein sequence ID" value="ROT67893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIS4"/>
    <dbReference type="OrthoDB" id="204305at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT67893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="438" mass="50055" checksum="A06256F96E92709E" modified="2019-04-10" version="1">MAVYAGLNRVGFDIKDLLQEQHAAREQPEVFPPWFLKRFDFEGESTCSDFSTQRGKDQRVLAYSYYTTNGSPDYFRYLSQLHGTAKDVERLYPGWIMRIYHNTTSTDVFGRKELCRLYCENDHVDLCHIHDLPGLGNLNKRGVVGRMWRFAVMGDPTVEVFLSRDADSWVLDREAAAVHEWLRSGRSFHVMHDHPVHRALMMAGLWGAFNKNQTLMRKMRDRMFNSPRNLDKAYDQRLLLNIVWPVVKNDVLNHDSYTCLHPSHINATPFPTKREDNKYCGWGISKGTARRKLSKKSSGSASPCAAHDPAPRIAESAKLWKAVDRLHNTILSVASSTVHRLSPSAVQDVVFSNKKVTIDASTCDDHGHEWRSAVDGMKPTLLSMDAFMSTFYHLDLRRRCLSCLLTTYLRTALLATDMVVSCGWPKATQRSAPWSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PIT2</accession>
    <name>A0A3R7PIT2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002050">
        <property type="protein sequence ID" value="ROT73236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PIT2"/>
    <dbReference type="OrthoDB" id="6365992at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="671" mass="75171" checksum="E87233C69835A156" modified="2019-04-10" version="1">MRQYALEVQASTRVVTEFASHSGLREPDLRDLPAASHEQDSRRAPADVPRPASRSEETLMDQLLLELLILDQEEERRRLALQARKRDGGLSLGGVACYVCEEAVDEGKFQSHLFFGAVHCRDCSLAVSSCEKFARARRRGGSESSSAGAPDTADGGAKCSHRALKWSHSPVGFLKKHLKRDLARERTCDIEGSSDLARSVSLYVEKLSSLQSFAPWRSALRKIMEFVISKSSEREREAARGESGISRGDRNLSQDPSKSRRKSCSSSESQSLRTPSVRWESSSSETRGRVAGQEPPEAFAKEFQAEPAPSTTEPEAHASSTASTLEADQHTIEEGHLVPQTVEEELVISEWEGDVINLQVGFPETPYTLVEDLDKNRMLRKSLRTDLDETDIAEGLSPLKVSLEGAGEGSRATSRDDFEKRTPRKSQSVRDTRTGRPTAEESNNKIPGISKASPYTKESEIIIVSASLLGLSGGLSDCPDFVFLEVDAKDIDGKRILRSTSEEEVDVEMVEGTDDKEEDELETETRKMNKEEQQRDERLRKRRRRLKALDEVENDVRRRSMRLKEEKEEEEDLWKAPKGLAEGKEDGEDLSSPPKEYNLRSKRRHRASKDLEECERAWTTVGRRDRDGVAESEGRPRGPEIHRGRSGLLSACRRLLQDPPIFGKVRLEAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLC1</accession>
    <name>A0A3R7PLC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002448">
        <property type="protein sequence ID" value="ROT70244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PLC1"/>
    <dbReference type="OrthoDB" id="535509at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01670">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.533.10">
        <property type="entry name" value="Death Domain, Fas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011029">
        <property type="entry name" value="DEATH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016729">
        <property type="entry name" value="FADD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15077">
        <property type="entry name" value="FAS-ASSOCIATING DEATH DOMAIN-CONTAINING PROTEIN FADD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00531">
        <property type="entry name" value="Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47986">
        <property type="entry name" value="DEATH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="2">
        <location>
            <begin position="86"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="207" mass="23151" checksum="A88AFB92B014BB71" modified="2019-04-10" version="1">MDNIKTDSAPLGSVSSDFQQGNPSRPQRQIYNITGGSAVHIGPVIHNIHGCNPRSQHKPQDMPLKKDVEELLKCSREIEERDKVEVSEHMGSSWKSLGRVMGFSAGQLENMIADHTRNVDRVYEMMSRWHDREAEDATVARLTQMIIKHPLRNEVSPSPDNRRTLSSGRRGPDPIKGGRELSLSASAFWRWAARRPGLLGLLGLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PQV0</accession>
    <name>A0A3R7PQV0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001189">
        <property type="protein sequence ID" value="ROT79771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PQV0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="42654" checksum="31760BE6A2359837" modified="2019-04-10" version="1">MNPSHRATARPLVASPVLTSPQRPLFRRLFSPQERETTVSHPLFRTSFLRPRHLPFCPDLSNVTSFPRLYRLTPPWYRLEDRRQRRMRRDDLSAPPPPRTANERLSDSHSTSTCQTSSCLPPTVLSGPSSHQTPTRPRQEVLLPTPHPYQNVPSPTSHPPCSDVLLPLVQTCPSPPPPLRRPTSSPPPPHPPVRRLPIPPPRPPTPPVRRPSPPSDKTEAFSPSRLPPPPESTSFSSSLPPPSQTSFSPASSPPRLSDVLLPLPRPPPCQSPSSRTFPQPVSDILLPRPPPTPLSDVLLPPLPPPTPSQTPSAPPSPPNPLSDIAFLLPPSHPAVQRPSSPLPPSPTPCRLLSPFPPPAPQGRRMAKEETSLKIYTRWSGNAALEERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PSW6</accession>
    <name>A0A3R7PSW6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative multiple PDZ domain protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001697">
        <property type="protein sequence ID" value="ROT76061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PSW6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="137" mass="14789" checksum="539868F2B23AC74E" modified="2019-04-10" version="1" fragment="single">MQHSREDRAYLRGKTKSRATLIAKSTFCQSCKRVNSLSAGGVAVASELRAIQPISPHLPCVPSLTKPPSPLSPSPQAATRETAVSALRSCSSPARLLVLREDPETIFTTTEEPSRFITVELRKSSPESVLASASWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PVZ9</accession>
    <name>A0A3R7PVZ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004334">
        <property type="protein sequence ID" value="ROT61144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PVZ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="509" mass="56748" checksum="8F200DFABB742C02" modified="2019-04-10" version="1">MIACSERTTQRRPLRCVSVYAFDPLSWFTASSPPPASPLIPVPLPFLPFPLSPSNYSFILSPPSPSTSFLLSSSSSHFLPPFLSSPSLPSSFPLLLRHFTSSFLLLCPSFLLSSYSVTSFPPFPSSLSASSSFRSLSPSLPFLPFLLLCHFPSYHFLSSSVTSFLLFLLPLSFSLIITHFASSFPHLPLTFFPVTYSLTFPSYTIIIILLSPSYTSFYSSPFPFPFSSHFPSSFPHLPILLFPSSPSFSFPIPLLPDHVSFFRFPLFIQSHIPFSFPLPYHFCLFPYSHLSPSLFSLFLFSILSFPFSLPIRLFLFFLSRFPFPFLLHISFSSPFLPFAFPSLPFLLLCSLSFSILFSLPSVVNLFFLSFSISLLSFSFSFPLLFPLSLSFFVSPLSYFSLPFLPLPLLPFSPSLFHLILYRFPPPPPSNTSLSFLPFSIPFSFSPLPSLPPSPPSLHPLTLPSLALSSPFSSLSLPPLLLLFPSFPPLLRPPPPPLIPSTSPSVIKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PW30</accession>
    <name>A0A3R7PW30_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004270">
        <property type="protein sequence ID" value="ROT61246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PW30"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="759" mass="85553" checksum="2CF9E3635AC639E6" modified="2019-04-10" version="1">MRQKESSTTHKTPNNPHTGRKKIPTRPQPKSSSDNHTKISNQTPGRDAESTTPKEEIPDTTPSIPSALTPGRKSAQHHTQKSSTPHQRSPTPTPEGVPNRHQTPKRPPPPPTPHPGEFRHHTKRSPTTTPQDPKHHPRETPTKSDTTPKQEFRHHTKIPPHHSRRSSDTTPRSPTPTQGEFRPPHQEDSDTTPRSPTPHQESPTPHQEEFRHTPTPHQESSDTTPTRSSDTTPRSPHHTQGEFATPHPGRKFRHHTKIPQITHRGRYSEHHTTEGVSDSHTKIPNTSTRESSDTTPQRSSDTTKIPNTHTQARVLTPEEVPAHHTKIPNTHQEFRTHTNQEFRHHTSQHPHPGDATPHRQSSDTTQRSPTHTPRGVPNHTNEGSYPNTTPGTATPRGSSESPTPHPADDATPHQSSRPQPNTTPRGTTTKDVSDTTHQEHQDPTPHPRSRNTTPGHHTREFRHHQAIPNTTKTHQEFPNTTPRGVPTPHQDPEFQGESSEPHQRESFDTTPKSGDDHTKSVRTHTPHHTTEIHSTTHTKRKSTTTPRSSTTTHPGTTTREEFQDTTQRRVPTTTHPPKHHTQRKFRTPHTKIPQTPQQGEFRHQGDQDPKNTTPETPTPRETRHHTRKSSDTTPRSPTPHQGEFRHHTKQEFRHTTPKIRPHPEEDRPESSAPHNISNTTPGRRAPHPGSPTPHLIRERTMNPPLLSVSTARQVPKESESGLFTAEKILYQTFCSISSLSWFHVSSSALPLLSGFIFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PWP5</accession>
    <name>A0A3R7PWP5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zasp-like motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000447">
        <property type="protein sequence ID" value="ROT85093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PWP5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006643">
        <property type="entry name" value="Zasp-like_motif"/>
    </dbReference>
    <dbReference type="SMART" id="SM00735">
        <property type="entry name" value="ZM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zasp-like motif" evidence="2">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT85093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13835" checksum="3E025D0E94C7E74E" modified="2019-04-10" version="1">MHNTSRHIRLFTVTGSLQQITQTQQSLTTATQQHQAPVSKQYNSPQALYSPENVQEVLRQQTSPTHVPTLKPVNKPQKSMGLRGMPLTYDPEQSATWQIIHEEENCQLITEHGPTESKVYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXC1</accession>
    <name>A0A3R7PXC1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019729</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01003685">
        <property type="protein sequence ID" value="ROT62425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXC1"/>
    <dbReference type="STRING" id="6689.A0A3R7PXC1"/>
    <dbReference type="OrthoDB" id="10263353at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF16">
        <property type="entry name" value="U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C19 ubiquitin carboxyl-terminal hydrolase" evidence="3">
        <location>
            <begin position="47"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT62425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="18671" checksum="92FF35CEE2B51622" modified="2019-04-10" version="1">MEESPFLYLTCDLPQPPLFKDEKKENIIPQVSLYVLLSKFDGKTGKEYQTYKENILKKFQLTGLPPYLILYNKRFTKNTFYIEKNPTIVNFPVKNIDLTEYLTEEVKQKHPEPIYDLVAILCMMVSQRQEPTDVTYSTRAPENGMNCKIFTLKKLSLRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PXD7</accession>
    <name>A0A3R7PXD7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000207">
        <property type="protein sequence ID" value="ROT85706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PXD7"/>
    <dbReference type="STRING" id="6689.A0A3R7PXD7"/>
    <dbReference type="OrthoDB" id="6339846at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="54738" checksum="D68F5ADDC5066D0E" modified="2019-04-10" version="1">MWLAGRSLPGCEADGLLHRDGTRWTLGCHQYSCADGVTSPPSILDTCCEVGEAVYPDGHNWTDGCMRYTCNASSVDTLAILATCCQQGDGVHADGDEWEEGCYHYTCASGSPEPTMISPTCCKVQDEVYPDGHTWTVGCHSYTCTAGILEDPILLPTCCQVGEEAFPDGFAFTEGCHNYTCTAGSLETVSVLSTCCEMGEEVYPDGHTWTQGCYHYTCNAGLLGDPELVPSCCEVGPEVYPDGHTWVEGCHNYSCAAGVLAEPSVLPMCCAVGDDVVVDGHTWEEGCHNHTCVTGSLESFLRPDFCCEVETEIHPDGDSWTEGCHNYTCIAGSLVPTALLPTCCEIGAEVYPDGHTWTEGCHNYTCVAGTRSEPTVLSTCCTVQDELFPDGYQWPEECQVLFCDAGKLKTNTTCCEADGTMYPNGGNWTEMCYWQTCVYGTPVTLHMKDSCKTALTATASVLGILVFLVIIVVAYFCCRTAKKGKSQNGKPVVYVNMAKEELLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2Y3</accession>
    <name>A0A3R7Q2Y3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA2/NAM7 helicase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_014785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002842">
        <property type="protein sequence ID" value="ROT67157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2Y3"/>
    <dbReference type="STRING" id="6689.A0A3R7Q2Y3"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45418">
        <property type="entry name" value="CANCER/TESTIS ANTIGEN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45418:SF1">
        <property type="entry name" value="CANCER_TESTIS ANTIGEN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="4">
        <location>
            <begin position="289"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT67157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="43364" checksum="28D23D5CD9BE2919" modified="2019-04-10" version="1">MTSLPIDLLSTMSSSDLLSTVSSLPIDLLSTVTSLPPPAEAGGGRARGPPPLQLQRRRPGRACPPARRRDHSGDVGAAVHPGAARRPLQPRVRRRGGPADRARVPAGAGPREQVSGQIVVAGDPEQLGPVVHSAAARRFGLDLSFLHRLCGSVLYQAQRMDDLSWVYEPHLVTQLCRNYRSHPDILAVPSRLFYHDSLAAHADRELPNPSCPLLFHGLVSDKLPGGGLALVVQPRRGLPGREVRQEPHRVRAQGSGYWNYHALQKAVVRAASGTWPGGALAGLAVEKIRVLLVTFGLAEGVKVGSVEEFQGQERKAVVVSTVRSSSELVELDLQHSLGFVQCRRRFNVAVTRAQSVLVLVGNPWLLRRDECWRELIAFCVARGAYRGPDLDAAAADEQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q434</accession>
    <name>A0A3R7Q434_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000247">
        <property type="protein sequence ID" value="ROT85569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q434"/>
    <dbReference type="OrthoDB" id="6372870at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="851" mass="89919" checksum="240BF54E83976099" modified="2019-04-10" version="1">MSLIHISRQEKQQHTSSHLVDISHSRPAATQEAPLTRSADTLTVPASLVPPSLPSSSSIHRVTHHQSSTKDQQQSPQISTIQKHQQSQTQHLTQQQQHQQQQNSIVQQQVPGHSLLGHNTNIVAGVAGAVVGDVGDVLGDKGTSGQVPGAAMQASHQPGMVTMPYHPPMVTAPSYMQPPTYDYNAYCRKAPHSPRSEGRHQCYGYGKQHQYQHGDLLPPDATMMPDPRLAHNPPMPMPGPFLETTDEPPPMRPEPASEHVRYFSVSHLVSHSNEPRKTSISGQQKDGSASHTEDKSKDTTRTKSGSRKSESKSRGAGGTKSSSQGDSHSRRRSPARGSQQGNSGSVAPAMWSNKSSTVHKQGHNYSAEALLSTQNYGRPTHRPPANQNYPIMAPNQMYQSNYSPQQMKNFVPNTSFGYTSHDRSGQSGCNPDYNFQLHTQASGSLAYGSNMAYMPTGYPYQNLPPSSSSMLSGDIMAPPHPAGPYPRFHEFPTDQSNFPPNPTFPLPLDPQDVCSGGGLMGAASSAMAVRAPHSDMQLVPSSSVSSTVAYSRSNSNRSSGNIGVSSSVGGSISTSNHTIGSSSGVSSKRPRYGESNMVSSGMGGSANLLEGGALAHIPLHSFTPPCDDPTLVHSNLFPGTAPRHQSNFLLGPDNLMPINTAQYPGTSTGTGSGGTGQLGAGGVAGPPGTRAGSSVVLPPGAPPGHVPFSPLRVMDRQQVNMAPPTAPHLSSSLSNFNLTSIIPEIDGKGGENNGGMGSTSRGTAIGNNEVLGAAIPGQARLPPMPSSLLPPAEPLKGLPTDANRLPPPVLNNSMNNIFTHTPHHQVGLGLNSSLPLPPTTFSGINFPTPDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QFA2</accession>
    <name>A0A3R7QFA2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Myb-related protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_016374</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003063">
        <property type="protein sequence ID" value="ROT65637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QFA2"/>
    <dbReference type="STRING" id="6689.A0A3R7QFA2"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015395">
        <property type="entry name" value="C-myb_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF25">
        <property type="entry name" value="MYB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09316">
        <property type="entry name" value="Cmyb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="10"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="50"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="496"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="581"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="681"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="581"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="690"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT65637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="870" mass="94955" checksum="1EAE9FA71AEBBA57" modified="2019-04-10" version="1">MAIAPPYILEDEKVIELVKKYGPKRWTLIAKHLKGRIGKQCRERWHNHLNPAIKKSAWTDEEDNIIYEAHKQWGNQWAKIAKLLPGRTDNAIKNHWNSTMRRKYEAEMTAAGRKKQRGGRPSSAQTPPVMASPVPHPQHYTHEYHHRPDMMGPPMSHAPPHLTQQTPPPPPPQSHIYTPNGGYTPTPPHPHQEFHPHNHFDMPPAMHTPVPINNTSPYGQEAYPQSYWEQNSPYSTNYNIPPQQQSSVHQSQPSHAPGTILDSIGVPVSTQVSDPCHLQQPSPRGTNVGIVSTAVLSEEIGPLHHQLPPTPGTILDCEGSPLSSEQVTTSTPTPPPGMPTPPLSQCNQYPPQLPQPPSVSSSSSDSVSPPLNQGFLLSPDKTSIYHDLGIISPLKYFEELGSLSPLKPDRGMEVFRAELDMGAFELLTCSPVKIKQEVIQELSTPKAVSACSVATSSSCSSSSAPSSSSTSTSTVNSCPISSIISSVPPLSTASAVTTSSTTTHNMSTNSAHNGSFSSLNSSRLSTPPILRRGRRKQPSPTKRSLLSLMEQNESLLTTPQKVTPVKSIPFSPSQFLNSPNISFDDGNLTSTPVLGGIPVSQSTPVQPPPPSSHPHHTSTPSESGGQPRTPKSRRVLIQPTPQTPTPLKNALREIEKKSGPLKHLPQTPTHLEDITEIIRKDTERDRSKFETPSVNSQSARNQSVINDSGYGTVKRKAPPPSGKENSPSKKARKALPYSWSTPGEIQVPGFCAEPLTLMPETPSKSLIGDSSVLFSPPSIIRDTLPDENHPLASTSLLGNKSPKKAREGEFGCVKRISFGEGQTTKANLSKLDVRWEMVACGKTENQRRLTEQARQFVTQNSTLKPRSLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QI89</accession>
    <name>A0A3R7QI89_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative tyrosine-protein kinase BAZ1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_013566</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002695">
        <property type="protein sequence ID" value="ROT68291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7QI89"/>
    <dbReference type="OrthoDB" id="784962at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090535">
        <property type="term" value="C:WICH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140801">
        <property type="term" value="F:histone H2AXY142 kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047174">
        <property type="entry name" value="BAZ1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013136">
        <property type="entry name" value="WSTF_Acf1_Cbp146"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46802">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE BAZ1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46802:SF1">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE BAZ1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10537">
        <property type="entry name" value="WAC_Acf1_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00571">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51136">
        <property type="entry name" value="WAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WAC" evidence="13">
        <location>
            <begin position="181"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="DDT" evidence="12">
        <location>
            <begin position="775"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="1369"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="1447"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="302"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="450"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="956"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1111"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1500"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1022"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="463"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="568"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="956"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1128"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1148"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1515"/>
            <end position="1525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT68291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1568" mass="177169" checksum="A96E1A40878E73D6" modified="2019-04-10" version="1">MNSGTNSRANTFPMGWSSNSNRKIMLNESNIRRNYTAYAARADAEAGTLLNTLARRPPSPPCTSTAPTPIRELELDPPDLLVTPMSLTPMSVVASLLKALEGGLSVYEGALCGRLRGVRSRPMFRAWWGNILWTRSMWRDVGGRSVSKGAASIPPKSESMPLLQGQPFRLIKPPDQMEPGRELFVIQHTGEKFVSKSDYEDRLALYSQSIWTCQCTGKSGLTHQEAWTSEAKVRVLLNASFPSPLLKPILQLIHHSTLPLDQLVEATSSLCYTRFHQGEELTLLGPQPVQVRVIGSKEAPVQIKTENGATEDEHATNEALQTPAPATPKVANGCTPSENENSVVNGTGNGVTESEETSPSSGKGKEDAAGKKKLLPLLYDVSVIGEDRTIVDVPAKNLQRTYKNPPKEHFRLFIRANAIRQRSSCYTPWNVAEELVKQYNIQGKYASIFTQPKTGPSIKKRKLEGQGEEKVKKPKSEKTEETVKKTKPKTDKETAKRVKRDPDAPKRKPGPKPGSKRTPKVSPKVSPKAESPVKTPPKLQTPVKLESSDSDDDVSLAVLASRSPKMKNGNTESPKSSTPPEQKTPPGIVPLVKSEKKEVPGGGKENSKKMKQATLFDMKTPKKVGAKSPGSKATPRRSPQKREITAESVMRLPLMKKMVSDYKLYKGVQGGGRKLVYTMDQVLKKISIQQVEVIPDEGIRNDLLKRHERIIEKRILTKMAPEEKEEYLKQKAREVAEKRIQTKRELKRKIEDKILTDTKPLPQPKLVSTPEEIPNSLFGDVAMIVEFIDCYREILVPEKKMSITCSKLLQALSAGTKGYKIIAEVISLLLHVILDDERFGERKELGVKIKDLTIHYQTAIELARLCLRKKETSDAVSQHSDDDMGEEQNELSDGLLEKLESCELYELQSEDIIMVLKALCHHAMASYAAIEHVEEVEEKVYSLYKERAQIKKQTLKEEMEKKKQKKEERIKKKTDKTSLGKKSPGRPKGYSPRKKAVTLDSFYGKKEEEEESGPDIISRVKNRRLTAEESRKERELLKQQEREQLLKEEEERKREMVVLEYEKVLNQKDCLIRLQPLGVDRNHDRYWIFKSMPGLFIEKGWVDSNTTYCTKPKSAAKGTASSPSKMIIKQESESDSDDKPLSAIKQELATTPQKKVSSTASPRGRPRLVKPPDDDEDDTFPSVGQNMWFHYDTIEEVDKLVEALAEKGAREAPLKTSILNHRKHLEETIAKPKETLDELEDGAKQLMESLREDIIQIERELTEGWLGSVPDFEEWEKKAQEASTQQELSECLLEVQRHIQFKYLKGIMAPIKKPMPSENPELPTEYEELENPAVQQWRDSVMNSQTLSRLHLLVSMFDSCIKWEKSIATKKCKVCRHQDTSIPLAICDQCEGSYHWSCMRPQLRETPPEPWLCPACQPKKNNRVNRERSKAGQGEEEPEVRGEIKQEKICRVCERGLGLIFCSKCPAAYHSECHDPPLQTRARKDWECVDCKNAAASKQKTRSGRSVSSRTPFQAEKETQEEFTKSHRKEELQNFCLLFSTSSPFLPSFLIFTSYPILFTTWFLGPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJP5</accession>
    <name>A0A3R7QJP5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_012125</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in transcriptional regulation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the snail C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002537">
        <property type="protein sequence ID" value="ROT69673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJP5"/>
    <dbReference type="STRING" id="6689.A0A3R7QJP5"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000226">
        <property type="entry name" value="Zinc finger protein 236 variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008598">
        <property type="entry name" value="Di19_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF104">
        <property type="entry name" value="AT-RICH BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05605">
        <property type="entry name" value="zf-Di19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="14">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT69673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="163" mass="18223" checksum="598330EB6572FC2D" modified="2019-04-10" version="1">MLAQPPLAPVSDPRGDEERPFKCPYCQKGFKGRENLKLHIRTHTGEKPYNCGVCGKAFGGRSDMNRHLRIHTGEKPYPCKCPVELLSLLPPNQLHHLRHLAASQCDMTAKITSCLAAKSHFSPSFFFSLNSSDFKRQQGHRALNLPKVGLETRGCLAMVSVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLW6</accession>
    <name>A0A3R7QLW6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000722">
        <property type="protein sequence ID" value="ROT83177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLW6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="455"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="597"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="909" mass="101046" checksum="904B49CD59B45910" modified="2019-04-10" version="1" fragment="single">SSSSVSPSPSSISFDFFISFSSSSFISFASSSGFSFFLFISFASSSVPFFLSSISSSSVLLRFSSVLFLLFIVSLLISSPSPLISSLLHQFFLLPLHQFRFFISSPSPFFSSVSLLHQFSFFSLHQFRFFISSPSFSSSVSLSSSVLLLPLHQFRFLILSPSPSSSVLLLPLHQFRFFISSPSSSSSVSLLHQFSPLHQFRFFISSPSSSSSVSLLHQFSFFLFISFASSFLLLPLHQFRFSSSVSFLPLISFAFHQFSFFFSCFASHQFSFFSFISFASSSVLLLPLSSVSLLHQFSFFLFISFASSSVLLLPLHQFRFFISSPSSSSSVSLLHQFSISIFISFASSSVLLLPLHQFRFFISFSISLFISFASSSVLHSPSSSVSLLHQFSIIISFASSSVLLLPLHQFRFFIISPSPSSSVSLSSSVLLLPLHQFRFLHHFSISLFISFASSSFLLSLFISFAFFIISFFLFISFTSFISSPSSSSSVSLLHQFSFFLFISFASSSVLLLPLHQFRFLLQFSISIFISFAFSSVLLSSSVRFFISSPSSSISLLHQFSFFLFISFASSSVLHLPLHQFRFFISSPSSSSSVSLLISSRFASSSVLLLPFISFAFSSVLLLPLHQFRFLHQISSLLHQFSIFFISFASSSVSSPFISFASSSVLLLLHQFRFFISSPSSSSSVSLLHQFSSSFSFSFRFFISSPSSLHQFASFISSLLPSSSVSLLHQFSFFLFISFASSSVLHLPLHQFRFFISSPSPSSSVSLSSSFLHLPLHQFRFLHQFSISIFISSPSSSSSVRLLHQFSISLFINFAFFITSPSPSSSVRFFSFASSSVLLLPLHQFRFFISSPSSSSSVFFFHHSPSPSSSVFSISFISSSVSPSSSVLHLHLHQFAFFITSPSPSSSPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QM08</accession>
    <name>A0A3R7QM08_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000699">
        <property type="protein sequence ID" value="ROT83338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QM08"/>
    <dbReference type="OrthoDB" id="6386492at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="210" mass="22948" checksum="27C31139B9D1B3EB" modified="2019-04-10" version="1">MEPAYEGGYYSGFGQDGYSVGNCGPYYVEEGGYNGSLGEPQMWPHGTTESVQGLHSASYDDHSYPYGQADGAEASLFRGSEALAFGADDYLEGAAVGGGLSPSPPLSVSGGGRQRKVKMYDWPKQDDPALEKRRQLAIKQKKKRDKDEREEIQMRLGLKKTEEEIKNLKMEMAMRGCNVSMMQQTLASYDANASYGYPEDVWAAGSPAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPM1</accession>
    <name>A0A3R7QPM1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000164">
        <property type="protein sequence ID" value="ROT85861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPM1"/>
    <dbReference type="STRING" id="6689.A0A3R7QPM1"/>
    <dbReference type="OrthoDB" id="8744624at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40240">
        <property type="entry name" value="PLEXUS, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40240:SF1">
        <property type="entry name" value="PLEXUS, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="310" mass="32693" checksum="57276BE84A53C681" modified="2019-04-10" version="1">MHSECRDYPFLKEHNRPPGGMVVDNGHSVVVCKDCYSSLKNQYIELERWGVPVEKRQYNWIQRPPPPEFHRDSSATGPKPVQGQISGAQPQLADPGVSSPGSHPGTPPGGLSQPRGGGSPRGSLGPPPGSSSAADDGVESRVTSGKVSEEPASSTSSTIPKTSTVVTGPVATTSDASCDGTIPSCCAPLQLKIGVARQGGKPPHALTQQSSVAASEGVNSGDASAIRSPPVDQLTHWSQKPKRNGAWERLPPIKASTHHQLLEDQKSRQSVIRGFSSPGVPSESDSRPQLSPHHPKQLLSPPHELQAKCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QR93</accession>
    <name>A0A3R7QR93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_006210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001796">
        <property type="protein sequence ID" value="ROT75258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QR93"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="488"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT75258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="587" mass="66010" checksum="24C2177E7460E464" modified="2019-04-10" version="1">MPHPAPHTCPTPRGLPHRRSLSSLQRHLPFLCLSIYRSAAVTLTFQTSFCLERRPGEWPPAERTRWSARESRVRVLQPFESSCKRATLESVTSQVWPRPFSQPGRSVPAAALSFGPRQWPCDGGCLEFPSLKRDPERDTMAEAPQRTKWQILLAALRSISVEPVMLLDGVAYSNMVVLVENLQMDKVCRVNLNHSAEVCGNLSEHKAVRDDMTREVSVFAMYNGIITSIIPLFFILFMGAWSDKYGRKTPLLVATLGHLLYALGYLVNSAVEAWPVEYLLFVALLDSLGGGTVSFLTAANSYMSDVTTEEARTSRLGLANSIWFLGGPIGTFIGTYIYQAGGYQVLFGTSLSMYLVSCAYIIFLLPESHGPFANVKKLEKILAPKQSLRLRESIVWVYGIDKEKKRDLMHTESVRERAKKISLVQMVKDFFNPRRFLDSFRCTLKKREGHVRIYILLLIFSNLLRKLGRGAYMYLFTRHVLHWQASDYGIWVTYKNLLATLGSLVAVPVLSAGLKVSDNALAMVGALSSVFDYILYGLVSEETYFFMWLAPLAALLVNSCAIAIRAMLSKYVTSDEVGEYDMSIRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVA7</accession>
    <name>A0A3R7QVA7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_001747</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001231">
        <property type="protein sequence ID" value="ROT79532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVA7"/>
    <dbReference type="STRING" id="6689.A0A3R7QVA7"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03177">
        <property type="entry name" value="GST_C_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03045">
        <property type="entry name" value="GST_N_Delta_Epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000034">
        <property type="entry name" value="glutathione S-transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000007">
        <property type="entry name" value="Glutathione S-transferase 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43969:SF9">
        <property type="entry name" value="GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01153">
        <property type="entry name" value="Main.4:_Theta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="40"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="127"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT79532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="257" mass="28735" checksum="64F20ADDBD5C8B08" modified="2019-04-10" version="1">MRRRRATTLITVAIEAPRETTPPRLPLTMDLRGSPRLPKMPVDLYYMPLSAPCRSCMLTAKAVGVELNLKLLDLMAGEQMKPEFVAINPQHCVPTMVDGDFALWESRAICSYLATQYGKDSSLYPSDPKTRALVDRLMYFDMGTLYFRFGEYVYPVMFRGETKANPEKLEKLHEALGWLDGYLDGHEWAVGNSVTVADFVLVATVSTFEAAGIDLSKHKNVTAWLARCKANMAGYEEMNAKGAEDFGKMAREKLGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QVG7</accession>
    <name>A0A3R7QVG7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001197">
        <property type="protein sequence ID" value="ROT79727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QVG7"/>
    <dbReference type="OrthoDB" id="6351323at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="619" mass="65246" checksum="5175496B61AA7FAD" modified="2019-04-10" version="1">MDLCRCVCIVDVVVSRSPRAGVHDELRAPGASLTHNTAHLPARVFVAPFSLSRLPSTHTSATITTLRITSRHTSLINPDPTSLTLSRLAVLLDNEAFTNLERATVGIESVPAGSPYSPELLSSLFSLSSLCSPVHPFLTTPGTPSMPFLSPNEASDSIQPASMGSQPASLVHESVSASLKSSGNGVPDPPPPSLAIGHTFPPVSGDTVSQALSTLTLKAEVRSTASEQSDRLLEEILQSKTQPGIQGSSSEDVPESKENSGKLPTTSTGNQASSTEGKTLGAGDAHGKDCVDVASSQVTGEEENVVDEKRDNQSIGSGLESSFYRGSATFSRHSSEDLTPPHSDSEDEKDDVQLILAKREMETSEEGKPANAPADTNNEGDTEDSGKEEDSSLQDVILAITSSHFKEKHNFTARTLYKSLAAVLTPILERNTFQEVLHSAMKCVKDSSTLKCPNCGGGVVVKAENVDHPNTAFRMQDGPRSSTPISQAVVQNAPSTAPSSESDSCPGESSESVSVCSEASSCVRRESDVEVISNPSVSSIEVLSEQQIIHDVILEEEGEEQKPPMPAVLNTDARSPANSPSINHKPELATNMQESSSSGSMTGSVCTTYEKTGSAPTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QXR4</accession>
    <name>A0A3R7QXR4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL40</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L40, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_024535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000848">
        <property type="protein sequence ID" value="ROT82297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QXR4"/>
    <dbReference type="STRING" id="6689.A0A3R7QXR4"/>
    <dbReference type="OrthoDB" id="5977625at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3440:FF:000001">
        <property type="entry name" value="Mitochondrial ribosomal protein L40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019192">
        <property type="entry name" value="Ribosomal_mL40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039145">
        <property type="entry name" value="Ribosomal_mL40_metazoa/plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13359">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13359:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09812">
        <property type="entry name" value="MRP-L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00083752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT82297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="106" mass="12648" checksum="9A2D9245B681826D" modified="2019-04-10" version="1">MSSAIRKRSFQLPEEVKDQRVALLKEWSHYKYQQHLAETTMIDEVMASQQHALEELRKVSEDLWLEAIQLDQTLLPYRARGPLRTPPIQDYDTPDGEYFNRTKKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYL8</accession>
    <name>A0A3R7QYL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000668">
        <property type="protein sequence ID" value="ROT83573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYL8"/>
    <dbReference type="OrthoDB" id="20035at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="296" mass="31980" checksum="D6E794EB4A64F735" modified="2019-04-10" version="1">MNQSPLEESPKSEHGDQPEWSVATQDQDHSTEDSNGGNDSERLSVESAEDALVVIGSPEHCDDSAREPPDTQPVEDSPPTSPPSSPLAIPPSMPFPPMSPTSPSPPLSSTGTVIQPPHMSSADITDSHSSTILASSPPVCPPSVQVPAAIFNDHALLQFSEVTQATIPPNVDLLSSPQVHYTESFGLIPEPFPRLRDAWHAGQLSLWFAEDITAEIVERCSVHTAASMQFLFHTMESGKQLECVMFASCTMSHSPPRPPPLRPDPLMQLINWILTAICTVCAISISKITDSKHLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7R097</accession>
    <name>A0A3R7R097_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_008496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000207">
        <property type="protein sequence ID" value="ROT85703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7R097"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT85703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="483" mass="51031" checksum="F767C4D5258D0F94" modified="2019-04-10" version="1">MGGVLGREVRGRERKKQGDWFFSHGRRVDMGGGSCQVAAKVAARSLPGRCPSLPTSLPGRCQVTFCHVASLQVTSLPGRCHGCHVAPGRLPRRCHVVARSPGRCHVAARSLPRRCHVAARCCHVAARSLPGRSRRCQVAATSLPGRCHAATRARQVAARSLPGRCCQVAASLPRRCHVQSLPGRCQVAVTSLPGRFAAVAAVAARSLPGRCQVAARSAARSLPGRCHAALPRCRCHVSLARSLARSVPAAVAARSPGRCQSRQVAARIAATRCHVVARSLPGRCTSLPGRCHVAANVAATSLPRAARSLPGRCSLPGRCHVAASRCQVAASRCQSLPGPLPGRCQVAARSLPGRCHVAATSARSLSRVCQVAATSLPRRCQSCHVAASRCQVAARSLPRYVAAALPALPGRCHVAATLIAARSLQSLLPRRCQVGCQRRCHVPGRFAATSLPGRCHNRQYVAARSLLAQVLPNAILNCLCYFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIS9</accession>
    <name>A0A3R7SIS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative D-beta-hydroxybutyrate dehydrogenase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019354</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003553">
        <property type="protein sequence ID" value="ROT62771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SIS9"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008202">
        <property type="term" value="P:steroid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313:SF50">
        <property type="entry name" value="GH26015P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43313">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="21057" checksum="06F5EAFBD42C2D04" modified="2019-04-10" version="1">MAVTYDKAARVLFWGGVSSALASLLALLGLASWWPAFLASWTLAGATYSVLASFRIFPDGKAVLITGCDSGFGFATALFLDQMMDVTQQEQIDSALSSVKDLLRPGEVLWGLVNNAGINPYGAVEWTSMSIFRNTCEVNLFGTIAVTKAFLPLIRSAKGRVVNVGSVRGRMASPLGAAYEVTKYGVEAFSDVLRRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SQ86</accession>
    <name>A0A3R7SQ86_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Guanine nucleotide-binding protein G(s) subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Adenylate cyclase-stimulating G alpha protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_011123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs).</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the G-alpha family. G(s) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002409">
        <property type="protein sequence ID" value="ROT70585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SQ86"/>
    <dbReference type="STRING" id="6689.A0A3R7SQ86"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007191">
        <property type="term" value="P:adenylate cyclase-activating dopamine receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007606">
        <property type="term" value="P:sensory perception of chemical stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:006178">
        <property type="entry name" value="Guanine nucleotide-binding protein G(s) subunit alpha isoforms short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000367">
        <property type="entry name" value="Gprotein_alpha_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF212">
        <property type="entry name" value="G PROTEIN ALPHA S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00443">
        <property type="entry name" value="GPROTEINAS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU369121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT70585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="114" mass="13496" checksum="F9B972E0F669F784" modified="2019-04-10" version="1" fragment="single">WLRTISIILFLNKQDLLAEKIRAGRSRLEDSFPDFARYQTPLDATVEPGEDPEVVRAKYFIRDEFLRISTASGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSM7</accession>
    <name>A0A3R7SSM7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COP9 signalosome complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_008313</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CSN2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002046">
        <property type="protein sequence ID" value="ROT73260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSM7"/>
    <dbReference type="STRING" id="6689.A0A3R7SSM7"/>
    <dbReference type="OrthoDB" id="194139at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000001">
        <property type="entry name" value="Putative cop9 signalosome complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058796">
        <property type="entry name" value="COPS2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25983">
        <property type="entry name" value="COPS2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <feature type="domain" description="PCI" evidence="9">
        <location>
            <begin position="255"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT73260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="444" mass="51750" checksum="057665BFC215A21C" modified="2019-04-10" version="1">MSDAEDDFMCDDEEEYDLEYSEDSNSEPDVDLENQYYNSKALKEDDPRAALTSFQRVLDLEAGDKGEWGFKALKQMIKINFRLGNYEEMMTRYKQLLTYIKSAVTRNYSEKSINSILDYISTSKNMELLQDFYETTLEALKDAKNDRLWFKTNTKLGKLYFDREDYTRLSKILKQLHQSCQTDEGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYKNDPEILAMTNLVAAYQNDDINEFETILKQNRTNIMDDPFIREHIEDLLRNIRTQVLIKLIKPYTRIHIPFISNELNIDATDVEALLVQCILDNTIDGRIDQVNQVLELTRGAEGAARYTALDRWTNQLQYLQFVIVTKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SVE2</accession>
    <name>A0A3R7SVE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001590">
        <property type="protein sequence ID" value="ROT76932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SVE2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="42832" checksum="3830F9AB2AF0C1A1" modified="2019-04-10" version="1">MASRTLCRNFGLQLGTRTVIRPCHFDVTSIPPPPLPPTPSFPSFSFSYALLSLLLFFVCLPFLLFLLCLLSFLLFLRLHWPIFSSSYALFSFLPSTRFLSVLLFLLRLLSLLFSSYVFPFLLLFLLRPPFPPPLSLRPFLPTPFLCVLLFLRLPFRPSPLFPPPVLLPFSLLLLSLPSISLRLFPFSLLSFLPLLPFFLFLTPPPPPPPIPASRFLPLPPLMFVFCLFLHPCPLSVFVVRPLLTCPPPPPYPPSLILNPHIFPKEELISLRSCRSLYSQSHARTSPFLPHHFPLTLTLASLLLITFPPFPLIYSLSPILPFPLLLLLLLQHDPLFPNINPPSPHLHFLLLLPSSITPFSSTLTPPPFSFCTRPPTPAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SX21</accession>
    <name>A0A3R7SX21_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative ankyrin repeat domain-containing protein 50 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_001909</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001253">
        <property type="protein sequence ID" value="ROT79366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7SX21"/>
    <dbReference type="OrthoDB" id="427518at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058018">
        <property type="entry name" value="AAA_lid_TANC1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058056">
        <property type="entry name" value="WH_TANC1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25520">
        <property type="entry name" value="AAA_lid_TANC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25521">
        <property type="entry name" value="WHD_TANC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Orc1-like AAA ATPase" evidence="6">
        <location>
            <begin position="11"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="TANC1/2-like AAA+ ATPase lid" evidence="7">
        <location>
            <begin position="231"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="TANC1/2-like winged helix" evidence="8">
        <location>
            <begin position="293"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="532"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="565"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="598"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="631"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="664"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="735"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="768"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="801"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="834"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="867"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="900"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="933"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="966"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="999"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1130"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1274"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1422"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="478"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1152"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1235"/>
            <end position="1250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF25520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1451" mass="155380" checksum="0435C2A9AB451937" modified="2019-04-10" version="1">MATDCGVPGRRFLCREWAWAKLWACLEQRPAAKTCGALLVGGPGTGKTALCTELVTPTASHGRHASALQARLLAHHFCHAHNAASLSVGCFVQSLVEQLAESPLLAGYDAKVQAADVRSALEPCALHANPDEALKRAVLFPLLELDPPDRTLLLVVDSIDETDLQPPSTAAPRDANLADANNSGPSRSIAELLATHHHLLPQWLLLVVTARRTSRSVIRQFAGFRKVALDDLRRGHVVRDVQQYILCRLDREPALRHHLSRETAEMLNQLHIKSNGCFLYLERVLDGVAEGWDWAKRWSLLRRVLAPDHELRVLLFHHSFAEWLLDVKHCTQKYLVDVADGHAMLAMCLSVEAPSLDVTQVHQLALHLSRIHVKPPLEHFHLPLWMEGPPTEVRYEELEQEEEEEEEGEVEAEVEVAAHENQDEGEAERDSQEQEGKAKEEEEEEQQEEVRQDTLEELACEVDLLQMKEQSMEEEEKEKDQVEEERLRQLEAENRDYEEEKDEEYVTMVPLPGHFVGEGTTGGRSTEGVDSGGRSLLHSAAHQGDASLVRLLLERGACLGLQDRAGQTPLNLAARHGHAEVVATLLGAGADPDHADADGWTALRSAAWGGHTGVVTALLAGGTQVDLADGDGRTALRAAAWGGHEDVVAALLRHGAAVNRADSEGRTPLIAAAYMGHSEIVEMLLDAGADVNHQDVDGRTALSVAALCVPASEGHGSVVMTLLERDAVVDHQDHDGLTPLLVAAFEGHTEVCELLLEYEADVDHVDRSGRTPLLAAASMGHAAVVERLLFWGCYVDHIDAEGRTVLSVAAAQGSQETVRLLLDRGLDETHRDNAGWTPLHYAAFEGHCEVCEALVEAGARVNEVDNDGKHALVLAAQEGHAAVVASLLDAGANIHHTSHDGRSALRVAALEGHKDVVHLLLCREADLHYKDADGRSTLYLLALENRLDMARFLMESNADVESTDLEGRTPLHVTAWQGHADMVALLLQGGARVDAVDKENRTPLQSAAWQGHAEVVRLLLEHGANVDHTCSQGATALSIAAQEGHEASVAVLLQYGANPAHSDRCGRTAIKVALKGGHIHVARMLEESLIQQQQAGGVGRGLAAPSSVGSGSTAETKPCSALLCPGLTASPAESPESTFEKRRSVASLGQHSSSKSSGNLTTSTHSSGGPRAPTPREAHLQQHQQPLAPPAPSAPPASAMSPVLSFTQQLQQCGRGRGRRHPPPPQPALTPLDEPASPLYASPPLSPLSDGPGGGRHLPAGAILEDDYTVPLQHSAVRPPRPSAPPSASRQRGEGVRSQVFLVGKRVSEGFSLLLVSLCTLRAFPGCRAQLDLPAVIGRRGGGVLSGGGGGGGVVPGLGGIPGMGVSVPGVGGAGSPGSSGFTFTQDQHMRIILGTRSPEPRPRRNGIVTNPSLKAAHAKAAHLLRNGLSGRPRQPPARPNGLPLKKETPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S8V8</accession>
    <name>A0A423S8V8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021802</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004645">
        <property type="protein sequence ID" value="ROT60660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S8V8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF3">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT60660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="41795" checksum="EBE57D2D9026331F" modified="2019-05-08" version="1">MEPAPSFSSSCLLLLFSSLPFVLVPPRLLPLPFFSPSFPPSPLSLSHLLFFLLLPSSFLPLLTPPCPYFSPSFCPSYLFLLLLPSSLSPCSCPKPSFPSSCFLLLFFPCLLSLSQSLLLFFLSPPPPPSVFSLSSPPFASPLSLSRSLFLPVFPVYPEPSLPLPLVFGPITPSLLPFSSSSFRLSLFSSLRLSLVLVLVYVLLLFVHLPLLFCFPPFLYLLSLPLSLFIVYSTLLLALLLRSQGSLLPVPFSPCLSPPFLSPYPPPLFLFPIFLSLHRPNPLFRFNPPFTYLSPSSPSSSNSPSSSIPFISNLPSPSHFHLHSSPPSPHPVPLILSTPVSSSPPHLSPRPRSTPSSFSPLPPSLSPSPSPPLSPLPLPPPSPEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SAN6</accession>
    <name>A0A423SAN6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Gamma-aminobutyric acid receptor subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_020950</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004263">
        <property type="protein sequence ID" value="ROT61278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SAN6"/>
    <dbReference type="OrthoDB" id="10479090at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051360">
        <property type="entry name" value="Neuronal_Pentraxin_Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277:SF125">
        <property type="entry name" value="B6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19277">
        <property type="entry name" value="PENTRAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00895">
        <property type="entry name" value="PENTAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019579656" evidence="11">
        <location>
            <begin position="26"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="932"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1023"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="13">
        <location>
            <begin position="324"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="12">
        <location>
            <begin position="431"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="650"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="657"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="669"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT61278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1043" mass="117130" checksum="A120EF16F0E358B9" modified="2019-05-08" version="1">MMHVVVMASWVLHVLAPGLMHLVSAYCKSPFTRSEVTEAGWPSPSCLARSVNIPLKGVLLRKCSSKPFLFLLTLIKIGNFESQIEAASDGGRSLALSFVVASADTVCNKNRERPAHSLVTSTSKWRLNAARVEGLRTKVLEDEEGALQTRAFGLQTDVERPASTTSFVRYDFRSEAEERPPIAEATLCYRFSIARYRSIVPFVSYAYSDKADNAILPEVPRLPFSLACVCSRPIHPLNAVCFHSNITCRHNNFSETALSFRGIRNESAIEQGRGEEQGQKRIQSNTDLDFYFNDEKETTDLRLDDTLDVWNHHCLVFSHPGFRIYVNGRLSERGRLSSPALDLPLNGTLYLGQEQDRLDGGLDPHQSFSGLLAQVNLWDYALQDDVIHSIANCTSNDQGNVLAFDTAPVELSEALTEVLGVEALCARPPRFVIVPERKSPSEAAAFCELADSRFYIPTEGEANERLFNDSRQFVGACGGKSYKLLFLGATDREEEGHWVRTHDGRPLSYTAWGSGEPNGGRKRNCLVQTKHSDRWGDVECDQELCFVCGRTNVDFLQLRGLCHDDEHQTRFLFDGYLRGKPFFRGYYTMLIFHSGDKEWLLQDTTDNVTVAVLSLAQETGFPIGRQTWRMSSSLCGFPAGAAVVLGLSTCTTQEFMCTDGSCVHRGRRCNLRDDCADGSDEQNCTIVHFSDSYHNHRPPPGPSVGAPLEIDAGVELIRFSKIDDINLAFNMEIEVALAWTDSNLRYKNLKEQEGWNKLSSLEVEKIWSPDVEFLNVNNGELRRLKSGVFVQRLGEADPPVFTDVKMDTMYQAQAGRLVQREQYYGSFNCHFGLFHYPFDTQSCSILVKLASADTQVIVLRNGSVFYNGRSELPKYSIRNIAAHLTARSDYAVLQVTFDLERRWSLLVLTIFMPTFLLLGIGYGTLYIQLKAFQVRAIMTLTTLLVLYTLFNQVSSALPDTAYIKMIDIVIIVHIAVERLEPGEAKPPKTVRVSPAEQMRPEGRWLLRVKSITATQVLEVSRKMVFPLIVSVFALVYWLAIFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SCW0</accession>
    <name>A0A423SCW0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003834">
        <property type="protein sequence ID" value="ROT62092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SCW0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="42238" checksum="7B0520E5AF31564B" modified="2019-05-08" version="1">MTSPDRSPSRFDAALSLSAEEYFADVNERYLAMSEEQKIQRLLRRISDIFFPPAFRLVEAQPNVDIDRTTTGDGGRGKPGCVRGSYSRQPTAPTDKCHDAQPREGHGGATPEARTSSSSRPSLWHCRPDTGATGRASKHLPSAQVFSSLARSHTDTPAGRKSTSSPPHTPHPPPPDPNPIPFSLPPSPPPSTLALLSILKLYNPNTRGLCSMALCHLNLAKGGSGECIRLFLVLFIFLIILIVVVITIITTYPLSLLLSVSFSLFLLLIIIAIIIIPIPPTISPSFRLPLPFSPLLHSAPLSLQTHTTYVVSSANPPTIPPSPLTTPPLPPFSPPNHPSSPSFPYSYPPLPPHSFPYSSSPSPPPPLPPSPLLLPSPLFSPFSFYRFPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGX1</accession>
    <name>A0A423SGX1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003430">
        <property type="protein sequence ID" value="ROT63500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGX1"/>
    <dbReference type="STRING" id="6689.A0A423SGX1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="466" mass="49899" checksum="89387AFF9FDE0C02" modified="2019-05-08" version="1">MRNDLLLAQRRRPLIANWNLFNGSGSINLSTTRPRSGSRVLTGATWATCQRDSRCLGSSKGTLERSRDSPATHHHLGLEDDPLDDPRLSVAALRPRSWSGGEAGMTSGPRQEDESDGEGEPSPSLSFGVRRSLRALFGSLGKGKGRERKSAPETRWAGAPRDGRKPKPSERPRSQFYVELPSDTTCDSSAPNPQPVIVVTPARAQTLPAGLSPSLGNREAGGEGRTCAPGQDLTQGHERRGRRPLRQLGVLVIPESLHGGRRPTGGGSLLADEDFPLSEKLQRFRHGRGDLGYAEEHSSPTRAPYTPSPPPKSPSYHIQPLEDPPPPHAPPLLVPPATIPHPKTRAGGAPEATPPGPHEAARVGKRIERATGPPNDTPPPPPPAHSAAPASGLPRPHPAQPPPNPPSPLPPARRLSVSNATFRRTPYPHTPAQPHDDPPTPILPHPTIQPPATRSPTLIPSCTWRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHA5</accession>
    <name>A0A423SHA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003420">
        <property type="protein sequence ID" value="ROT63572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHA5"/>
    <dbReference type="STRING" id="6689.A0A423SHA5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="530" mass="59129" checksum="EB63F126FF0A7224" modified="2019-05-08" version="1">MTKYKDHVSKLNESLQNERKKQAELVERIKELEEQKLPIKEKLHESELTLKRLGNENRSLEAQIKLANSKMKEMQKQWERESFGFTGRSLGRATVSETRLSEIMMPRPSSSSTEEDSINNSDHLLLPKSSKNPSKVMIRAVSSDVVFRKPTRQNTTLEKQPKSSVDIANLAVAATGKKKITPSLEKVMSDKSLGHSVPRDMLFNCEDEEELFSNKYLIDMQVGRCSTLDDPHWKRLSELQRRNSLYPPHMRSAYPAEMQFRPLQDFDDDKLRAGNAVEDRQLLNLTQATENLGLDSPAFNLRKRKSLSDSTHSETSLDSSGGKRSKRLSTSYSRPGPPTPGRKSLSRADKENRAENSSPVSVGSRRSKVSPKSTYSDGSPVSTRSRRRTNARSTQSPGSSSTVSTRTPGGRSNHSGRSPANVSVLSKKGMTPRGKRGLTPSSLRKILSKGKSPWRKLENEAETPRGLGDSTGSNGSSKLRIFRRPFGSRNYNVLSASLRSQENPLDLNDSLTVSTGRSGLTVDRKSRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SII0</accession>
    <name>A0A423SII0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003338">
        <property type="protein sequence ID" value="ROT64030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SII0"/>
    <dbReference type="STRING" id="6689.A0A423SII0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="634"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="667" mass="73703" checksum="D22C4DD68117B37F" modified="2019-05-08" version="1" fragment="single">KTTRSRRQPLQLTHIYPVSQQTTATTDHPLLHNKTNPSIGLFYPTCLKQPEPTTSPNRNLFLCLPNNTVEATTNHLILRNENFTELSPTSQRQPNQPQHLTDIYPFSSDQQQIVDARGPNRTKIVIEGLSRGFRYAFTVQAYNEHGRSNHSLPAASVHMLDLSEGVASSSMDSSQSRMPRLILLLLSLTGTALLIVNVSIIVCFLRRRAQRRNLSDSSSKFTLSTLPSSKSTFDVYAPAATPPAPHVDHLPLTAAGTISPPDYQIRARDRANPPPSPSRWSATRRTTRARLPACPSPQRRAPAPHVTPPLASSSPRAKSASPLLNGGIRGPGDAFRPEEKSGSFAHKAIYCKTPQLSPQLGRSMTLDRQPGGLQVPSKPDVCPRSSNSREPLLQQSPYPEEDRVSLLSHHSADSYSICRGRNSPKASSYRSPAKPTTQVIYHGQPHLQKHLEQQQYSQDAPCNCRQDPQPPQNPCVQASASFTDLDPLRQAPHHSGCCCATCRQPLASSGLEDLPGRFSASGPRRSCLKSSHLSSLQRSHSDRAYTYSRPRSADPRDIELQNTCTLCTTHDPQGYQGVGPAYGRAQEYPMYYGKPQDAPEESLHGDLHAGYRTFYRESKWSSATPDVCKVEHASTKRVGWKEELLESPRPGQDDGRTSVTKEMDIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SL71</accession>
    <name>A0A423SL71_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase-activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_017138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003168">
        <property type="protein sequence ID" value="ROT64933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SL71"/>
    <dbReference type="OrthoDB" id="19923at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001136">
        <property type="term" value="P:negative regulation of endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="119"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="299"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT64933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="489" mass="55399" checksum="F18F639571E0ECBC" modified="2019-05-08" version="1">MREEILQRHGHTHTQPRKHSSARSVALLKSRGNGSVIAARIASAITPCGGPDCRRASRGLVPAVLLHCDLPELLPAATDYLESPVSDGTIEENFEAELGSALGEEDEQALHHTFTDDNDFTDIARHGIVDIIGDDTYGRKVIVVSACKLPSNKYFNHEKFLKYLMFTLDQYVEQDYSLVYFHYGLNSKNKPPVSWMWSAYKALDRKYKKNLKALYLVHPTNFIRVVYNIFKPAISAKFGRKVMYVNYLHELQQHLHLSQLPIPQCVQQHDQQLVAKLKSLPKTTGSGTNKPLPTQQFGVSLQYIKDANNQDPIPPVLKNCITFLDHPDALETEGLFRRSGAAAVVKSVQERFNKGEEVNFVLETDVHIAAVIIKTFLRELEEPLMTFELYDEIIQFQGLSKSERLISIKQILLEKLPEDNYLVLKFLVNFLSKVMDRSDLNKMTASNLAVVFGPNLVWPRGGQMSLNAIAPINLFVENMLSYHHQIFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLJ8</accession>
    <name>A0A423SLJ8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulator of nonsense transcripts 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_016939</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003141">
        <property type="protein sequence ID" value="ROT65116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLJ8"/>
    <dbReference type="STRING" id="6689.A0A423SLJ8"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase/UvrB N-terminal" evidence="1">
        <location>
            <begin position="83"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="181"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="292"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT65116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="46747" checksum="84F1568E78E6117F" modified="2019-05-08" version="1">MSVDAYGPSSQSLTFYDTEEADLLGADTQGSEMQAALRKFAVDDSSVSPYIYHRLLGHVEVDELLFRHIYLPKQLSAPNLPTLNNSQQYALKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKQTGGSVLVCAPSNTAVDQLTEKIHKTGLKVVRLCAKSREAIDSPVSFLALHNQIRNLEDNGELQKLQQLKEETGELSSADEKRFRMLKKQAEKTLLEAADVICCTCVGAGDPRLARLKFHSILIDESMQATEPECMVPVVLGAKQVILVGDHCQLGPVVMCKKASRAGLSQSLFERLVVLGIRPFRLTVQYRMHPQLAQFPSNFFYEGSLQNGVVDADRTMKGVSFPWPQQDKPQFFYVTSGQEEIAGSGTSYLNRTEASSVEKLVTRFLNSGVKPEQIGVITPYEGQRAYLNQQLSLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SM27</accession>
    <name>A0A423SM27_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cold shock domain-containing protein E1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016782</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UNR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003109">
        <property type="protein sequence ID" value="ROT65266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SM27"/>
    <dbReference type="STRING" id="6689.A0A423SM27"/>
    <dbReference type="OrthoDB" id="74319at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056400">
        <property type="entry name" value="CSDE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024642">
        <property type="entry name" value="SUZ-C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12913:SF1">
        <property type="entry name" value="COLD SHOCK DOMAIN-CONTAINING PROTEIN E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12913">
        <property type="entry name" value="UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23456">
        <property type="entry name" value="CSDE1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12901">
        <property type="entry name" value="SUZ-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51938">
        <property type="entry name" value="SUZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CSD" evidence="7">
        <location>
            <begin position="175"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="7">
        <location>
            <begin position="250"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="7">
        <location>
            <begin position="329"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="7">
        <location>
            <begin position="494"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="7">
        <location>
            <begin position="721"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="7">
        <location>
            <begin position="875"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="SUZ-C" evidence="8">
        <location>
            <begin position="948"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="677"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="677"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="691"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="999" mass="110846" checksum="A136B38EE5B3D4A4" modified="2019-05-08" version="1">MDPQWTLFQPPISEPAVLDYNGGTLHHHNRYNGFYESPGSGHHQSRNSHSSIPPPSPTFSSSSSHHNMFSSHMNNQSNQQSSQSNHQTSHHSQQHSQQPQTSSQGPPRSPQLSTSSSNYYSSNSSSQYTPPVADFKIGTFTLNANGFPSESNGPETTNSYSHTNGLSSNNSQSVRETGIIEKLLQTYGFIQCCERQARLFFHFSQFDGNTEHLRIGDPVEFEVTFDRRTGKPIASAVTKISPEVVLSEERVIGIVTTELRSESGGEHQGRITYENRGECFFLPYGKEDVEGYVTLKPGDKVSFQIATNQRTGNLAARHVRLENPAQPVKYQGVVSGIKDSYGFIERADVVDEIFFHFSEAKGITGGLKLGDDVEFYIQTRNGKEVAANMVKLNPGTVVFEDINQEMIKGQVLKPIEKNSRLYQKDPLDGRIRYRGKDRSEVEVKFGERDQKGDFTLRHGDWVQFNIATDRRDHLQKATNISLLDESFKVSGEKREQGVIVALKEGFGFIKCADRDARMFFHYNELLDPEHEIAINDEVEFTVAQDTTNQSPNRQSAIRIQSLKKGTVKFEVLVKEGLQGQVTVEAPGSPRSPHKNSQMLTTEKMQEPGVISYTLDGVKQTINYYANNCDKPLQSGDKVEFSIYQVKRTKELVAMGIRLVRGQASVRPTANNLTSAATTGLSLRSSQTNAPSTPSNGNVTSNSSTSINGKSNTPGPRPSATLHQGFVAALKDTFGFIETISHDKEIFFHFSNVEGDANNLELGQEVEYTLSSRTGPGGKVSAENVRTLAKGTLQMPKILGDIFEGTVLRSMRSINPDQEEYSGLVCVGNEDEGLEQYEFGITGVVNKRELLQPGDQVTFQLDESRRAVSIRAIRKKLIATVDAVKGQYGFLNHETEEGKKLFFHQSEVKDGTILSPGDEVEFVIITNQKTGKSSACSISRIMSKTAPSQRPDRLISRLKNLNCDTSKPRMTVLRQPKGPDGSKGFKLQRTISELQSQVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQH6</accession>
    <name>A0A423SQH6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002935">
        <property type="protein sequence ID" value="ROT66431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQH6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="396" mass="42508" checksum="0C55131C5E44AE57" modified="2019-05-08" version="1">MGKARKRQEGKQRKDVRGSMGRGGEGRGDFRPSSASCQILSRYGKHFRVDTPRGPGGRERAFLGGGDHHPSVILFLSLSPFPSPSPPLTPRALRSIPPHATPLPLPPSSATHASPPLTPTLPPPSRHASLPPHAHAPSPLTPTLPSPRTPTRSPPPSHAVTPPLPTLTPTAPLPLTPRPAAPPSRPRPQDTGSWNGDEGGWEIASLVSVQVDRSPSLALTLLPPSCTPLPRPPCFPSPHPSLSTLYSPPLPLTLHPVLPPPPAPCLFLRSAFSFSFLFLLCSSSLMFFNLDRQFCFVLTPAILSFSLLLSFSCSSFVYLLFSPFLSSCSFFSPLSAPSTPLPPLLLLVFFLLRLLSSTSFLVFFLLRLLSSTSSFFYSSSSSSSSLPSTSLPLSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423ST11</accession>
    <name>A0A423ST11_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002821">
        <property type="protein sequence ID" value="ROT67330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423ST11"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="43616" checksum="C776B3A21632E25E" modified="2019-05-08" version="1">MCPLPPSLRLSHLPSISTFLPYPFLSPFSSFLPFSLYVYLIYSIYLPLPPSLRLSHPPSNLNLASHTLACVLPFFSLCLAYLISILALSSLLPSIYIIAPVEFRTLPDSISNTCFPFSFSLSLCYLSSICPPPSLRLFTPPLSQPSSLFLPFSPFSLSVYLSILSSTSPLFSCPLSSPLSISTLPFLYFSLSACLSIYLSASPSLPPSISLPPISTLLSLSIYLSIFPPSLLSLLPSISTFLPPFLSPFLSLCLSIYLSASPSLPPSISPSPLSQPSLPSPFLPFSLSLSIYLSICLSLPPSVYLTLPSISTFLPSSPFSLSLSLSIYLSICLSSLPPSISTPYLPLPSISPFLPFSLSVYLSIYLPLPLLPFLPFSLFCFYGRISVSYSILLMRLIPHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SU09</accession>
    <name>A0A423SU09_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002779">
        <property type="protein sequence ID" value="ROT67680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SU09"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="421" mass="46644" checksum="F68208A91D01CEC4" modified="2019-05-08" version="1">MYLPLPPSLSRPRRRRALPSSIHSESTIDLKTSAAPVAFCAGMQSLCMSPRTSARTARTIHEAAATPRERLGWLAGQERPRNQTFSKQVTCETFLLSREGETRMWRSRYTIIPHNVMQHSYALVHLEAVPRHTAIQPATRPLQEMPLSVCASEARSPFGGPSTLCEAGIHYCYADKGFCTAFTPAHPVSASERGRTNTEENNAYSTTHTVVCCRDVMPSRRGVISSPFHALIFIFPNGAFGQWRDGRLRVSSLPHSLKHRRRHSAVSFLITMQMRKVKQCRSLFNKSSLYALRPPPLHFSSPFHVNIRLVSYAAIRSRSALEPHLSLKPDTRTIGGRGLIEAKQHSRSVRGSLSTSSYSAERTGRASQEGPARPSGDAAPTPIIRLAVTSPANPSNRILGQMSSRRPHACLFLAKASHMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SU68</accession>
    <name>A0A423SU68_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002758">
        <property type="protein sequence ID" value="ROT67782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SU68"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="378" mass="43071" checksum="EEE8E28392391B66" modified="2019-05-08" version="1">MEGEKGSKIVSQQLLKGNRGMYYTESDCSAISTRCVILLRCSLGQFRCMPLGTFSSIIIIFTPRRYDTIEPANGTYIPSAHSAHGHSHEPRSLHITSVQQNQHSSPLQTVTTTTVTPYHVSHTPSRHAATTPRTTTRRTTKRTDYQTGTDTQHDTSHQNATHHERTVYHDDYSDHTTGHAYSYTTIYRPRHTSTTSHDYTAPHHRATTSDHRHDTQTPTGQTHYANCHSRHRTTSTHDYTRTNPPYDTDLWSRDHNPPRLRSSPHLHDYTVTTSTDYHRQTTTSATTTDDYLRAQRHIHDHDYGTVTLTPPTLPPRLYHCYDLPPRLASSATTTVTDHHHVSLPPDDTPCHHHRSDYPTVHTTLARNSAQCTYQANDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SX95</accession>
    <name>A0A423SX95_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_013032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002631">
        <property type="protein sequence ID" value="ROT68809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SX95"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT68809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="408" mass="43410" checksum="B7B45C9888F24CD0" modified="2019-05-08" version="1">MTPRSTPLPLVPPPPLFSHCPFSLPPPLSLSLRPSPFLASHWSSAPGLQPSLRFPFSLPSPPPSPPSLLTFPPLPSHPFSLSLTFLPCATPFTPVDQVPSVPAPSAGARAARPTRGNAAVRGGRRSGSDRPRRGAAGPPGPPPARALRDPQAARAPPGERLRGHSPRDARRARHRRPGGARPTPAGRARRRPARSRAPPGARQAHGRPRPRALPRRPALPGRRRPARRARRPAVDSGASASPPGGPPAPRRPAPPRRRRAARRPRRRRRPARAATVGHPPPGRLPRPSARAGGRRPGPAAHAGRRALHPRAAGRALRWRSPAARPPWVRPRNGDAGRAAGRGHLRAAPPGPAALPRRRAAGARALRDAGRAAGRRPPASPRVAPPPPQHAPPRDAAARRPGRRRPQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXE4</accession>
    <name>A0A423SXE4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_012978</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002626">
        <property type="protein sequence ID" value="ROT68859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXE4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT68859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="48484" checksum="71A327E3C2623DBB" modified="2019-05-08" version="1">MKSPPMSPWARGGGGFAWMPEFISDFVGDVGREKGHGFAARHCVGWTYVNAKKGTGFALRGLGLGYYGRKGNGIALRGLGLGYYGREKGHGFALRGWDVGLLWMRKKDTALRCVAWDVGYYEREKGHGFALRGLGRGLLWMRKKGTALRCVAWDVGYYGREKGHGFALRGLGRGLLWMRKRARHCVAWPGSGLLNAKKGTALRCVAWDVGYYGREKRTRLCVAWPGTWVTMDTKRTRLCVAWPGMVWDVGYYGCEKRTHFALRGWDVGYYGHEKGHGFALRGLVWFGTWVTMNAKRARHCVAWPGAWVTMDTKKGTALRLAWDVGYYDEKGHGIALRGWRGYYGHVGWFGTWLLGHEKGHGFALRGLVWFGTWVTMNAKKDTALRCVAGTWVTMDTKRTRLALYGLGRGLLGTKKDTALRCVAWYGLGRGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SXY3</accession>
    <name>A0A423SXY3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ADP-ribosylation factor GTPase-activating protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">ADP-ribosylation factor 1 GTPase-activating protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">ARF1-directed GTPase-activating protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">C7M84_012761</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="21">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002607">
        <property type="protein sequence ID" value="ROT69104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SXY3"/>
    <dbReference type="STRING" id="6689.A0A423SXY3"/>
    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030100">
        <property type="term" value="P:regulation of endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000008">
        <property type="entry name" value="ADP-ribosylation factor GTPase activating protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46395:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 18" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="20">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="296"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="19">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="414"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00071258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00077418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00081514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROT69104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="470" mass="50957" checksum="68B7F11435A370EA" modified="2019-05-08" version="1">MASPRTRRVLAEIKPKDENSQCFECGTHNPQWSSVTYGIWICLECSGKHRGLGVHLSFVRSITMDKWKDIELEKMKVGGNRKAKDFLFSQSDYDHQAPLQQKYNTRAAALYRDKITSLAQGKSWSVESSQAKNHQSTTIPKSVSTPAFKSGDYQGGYQGGFTDPSLKTQTEAFFERIQNENASRPENLPPSQGGRYTGFGNCPNPPPKSASTEFFDTALSSLTSGWSLLSVGATKVAGKAMEYTNIASEKAAEYSHTISDKVREGKLVDEISSQAAALGQKVSEVSRRGWNEASKVLNTGGSGGTLALTGGSGGPHERSSLLLGPGDGYQRLDNARKEDAQTGLGLDLDPEQTSRNSELAPEDDSSMWEKGRSSDGWGDDNWSNDWGSGNNSLTTSPTQGGRNSATPSPNARASKTNSHSSSSGKMKASKSKESSQEQQLLVDLGNDSGNNSKGHTWDNWDDDWEKVDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SY04</accession>
    <name>A0A423SY04_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_012638</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002596">
        <property type="protein sequence ID" value="ROT69166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SY04"/>
    <dbReference type="STRING" id="6689.A0A423SY04"/>
    <dbReference type="OrthoDB" id="9996086at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="9" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="13">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT69166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="127" mass="14010" checksum="4CE99B7BA7A49BE0" modified="2019-05-08" version="1">MREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFMAWTPYFVINWGGMFNKPIVTPLLHLGLRLRQANAVYNPIVYAISHPKYRAALEKKLPCLACATDGRDGGSDAASTTTTEASEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T0F7</accession>
    <name>A0A423T0F7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002487">
        <property type="protein sequence ID" value="ROT69974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T0F7"/>
    <dbReference type="STRING" id="6689.A0A423T0F7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="461"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="559"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="615" mass="67163" checksum="81C42F49A10EF3CC" modified="2019-05-08" version="1">MSGPGSHYMLWRWCSLSGPAKTHSQNPRPKPTAKTHSQNPRPKPTAKTHGPKPTGTKQKPTAKNPQPRPKPTTKTHAKTPQPKPTAKNPTHGQGNPRPKNPQLKPHSQNPPAKTHKPKQPTKNPRPKTHSQTPQQKPTPKPQAKNPQPQPTAQNHSQTTHKPKPTPTAKNPQPHGQNPQAKNHSQNRTAQNPRPKPTTQPTAQNPSQAPKPTANHSQTQRPKTHTKTPQPKPDAKTPTAKTHKTHTKPTAKTHTKAQNPTATRQNPRPSSHNSPKPTAIKPTKPTAKPTAKTHSQNPQPQPTKNPRPKPHSPNPHQKTHATNPPHNPSKPHKHTPQPKPTAKTHSHKNPQPKPTAKTHKNPQPNPTPTAQNPQPKPHSHATPKQPKPHSQTHGQNPQPKPTAKTTGQNPHSQKPTAKTHSQTHAKTHSQNPQPKPTATTHGQNPQPKPTAKTHGQNPQPKPTHKPTPKTHAKTPKNPHTNPRQKPTSQTHSQNHTKNPKPTANPQPPQPKTHTQTHGQKPTAKNPQPQPPQPKPTAKPTHKPTGQNPKTAKPTSHKPTAKPTASHTQTHSQNPPKPQTHGQTHSQKPKPPKTHSQNPQPRPTADPQSVAPPKGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T393</accession>
    <name>A0A423T393_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_010785</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002370">
        <property type="protein sequence ID" value="ROT70911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T393"/>
    <dbReference type="STRING" id="6689.A0A423T393"/>
    <dbReference type="OrthoDB" id="8173462at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19526">
        <property type="entry name" value="RecA-like_PEX1_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000149">
        <property type="entry name" value="Nuclear valosin-containing protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="343"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT70911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="62771" checksum="D4FCEEA840CB36DD" modified="2019-05-08" version="1">MLLCIGPEGSGKTLLLRRLLNLNKPDISMTTVPTVGVNIVTLQVPEMLPINIRELGGSMAPIWHNYYSGVRKVMYVVDVSNLTHLANATLLFMELLANPKLKTAQGWPARHCFISLPRTWMHLVHPAHTPTFQLEVSSGQSILLSWAGDMHMPTSGEENSILWQDLALNVDSAQSAILSQMRVMGLGQTLPLWLDGGVCIMLTATSIDPSVPCVVLHPMTQVEVHPPPENEGAEDYTLSPQGCHYFPCTFRISPLETEGRVKAFMTMLNEHCEKFAATKEGISLCQCFPEADEHCVFCISLSEKKADESFRVGGMKDAKKILEETLTWPSLYPNLFNKVNLRLRSGVLLYGPPGCGKTLLANAVSAYCQLNFISVKGPELLSKYIGASEQAVRDAFERASSAKPCVLFFDEFESIAPRRGHDSTGVTDRVVNQLLTQMDGVEGLTGVYILAATSRPDLIDPALLRPGRLDKCVYCPMPSEKDRKEILEVLSQDVDLGEEIDWSEVAVVLNKTDCVLSRASNELLNAMRFDELKEYAPQQLTTFEVSALAGKGLRPLLEWIKGTKPKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6I0</accession>
    <name>A0A423T6I0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-rRNA-processing protein TSR2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_009819</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in 20S pre-rRNA processing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002239">
        <property type="protein sequence ID" value="ROT71848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6I0"/>
    <dbReference type="STRING" id="6689.A0A423T6I0"/>
    <dbReference type="OrthoDB" id="263560at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="298" mass="33862" checksum="EC94B9C3CEC049DF" modified="2019-05-08" version="1">MESLFGKAVEVTLKNWNPLQFAVSQQMGGRDSIAKRDWFPSVVEDFFYKNEDLDPDEVADFIATIMDSEFNTLVEDDSDLEVATVLCRFYRLSEAGEKDKIQEELEKMPKYNLDSCVVQDTENETEDDTHEMMTDQLTELQLHENGGDCGGDNGQGERELTELEKQQLQDEADGWTTLSEKHKTLTTKGTAHLLTVVASALHFCRSLWISFSHYLLKIHWRPVSSSGSRVVAGGSGQFYAGKCWLSTFYRQLLKRQDESRFDVTAKTNKGRGLMTRGFCTGPYLLALMRVLPPEHSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7M5</accession>
    <name>A0A423T7M5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002155">
        <property type="protein sequence ID" value="ROT72453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7M5"/>
    <dbReference type="OrthoDB" id="9523568at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="201" mass="22556" checksum="74DFBB787E84C862" modified="2019-05-08" version="1">MSLPSRVTGGPIRLKDDYVGRRSLSSLTLPSSLPSSQARVPLSEEPPLLRPKERHVQSLSYWKVGCAESVWSLKIPLAPLMDKEIFGTGVSIKEEISGDVTEEMWLEVKEEPYADEANDEVFSLSVGIRRSGFTYANVNKEKEPSERVIYCSVNIKRRLRGRSRSSLTLPSPLLSSEARVPLSEEPPMLRPTERHMQSQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8N9</accession>
    <name>A0A423T8N9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SNF2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002107">
        <property type="protein sequence ID" value="ROT72825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T8N9"/>
    <dbReference type="STRING" id="6689.A0A423T8N9"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SNF2 N-terminal" evidence="2">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="198" mass="22146" checksum="788E6A1FBFFDBC4E" modified="2019-05-08" version="1">MRRSLAPSQLLKRSLEINRESDDRIGSPVTSKRKKTVENECSGIPLSPYRAPLHPIVNSTQQAPSTPSSSHEALIKKILAKPFKIPIPNYVRQGSCSLGIRRNGVRRPLHDPEEPNALVFVHTTSVVCARKTHRKFGVKFMYDCVTGKQIEDNFGCIMADEMGLGKTLQCITLLWTLLRQGPDCKPLIEKAIVWHPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDD4</accession>
    <name>A0A423TDD4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001887">
        <property type="protein sequence ID" value="ROT74488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDD4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="464" mass="49006" checksum="7CFE1FCDA6A4C47D" modified="2019-05-08" version="1">MNSSGSEGDFLGSPFSRASWRDSWSLSGASSVACGSPSPGSFGESYSCGPYPLSESTSATSWDSILNLLGSHFSGYSGDFLGLIALTRFIPGPPLSPLSPHSPLSPLSPDTSLSFLLPLPLASTTPPLSSLPILSSLSHSSLPSPFFLLTPLSPFSSLSLSHLQHPLSPLLPLLSLLPSLPSLLFPLSPSRIHNTPYLPNLSSPLTPLSLLSPHSLSLYPKPQPLSPLPIAIIIPPFSPLSLPFASKVPSLFLSSPPSHLLCLSPLPLTPPFPLPSPPSLPPSPFSPLLPLPSPPLFPPPPSFPPFIPPPSPSPFSFPSSPPPSSPPSPFFPFPFPFSPPSPSFSPLLPFLSPPPPSPPHHSPPSFLSVFHPPLPPSFPLLPSAHHSPLPPFHPLRPPPPPLPPSFPSSSSLPLPFPPPQAIPEDSPRPMSTSGDFLIQQRHGRDEKVAGRMSSPSLLICGIFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TDV2</accession>
    <name>A0A423TDV2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001867">
        <property type="protein sequence ID" value="ROT74649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TDV2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="189" mass="21158" checksum="CEE43ADBD59979E6" modified="2019-05-08" version="1">MRRGRGSHSIYKGRARTTFPPSSLHTIYLDIRKPSWSAERDTSLSRMKLCAVLVGLCCLALAPAGTQASSVKERVKRDGGPTSILSTLSPHRRRRQTRVRQWRTVVHVGAAFWAKGRRRQLLAGRLGALRQWQLPGRRWAKGLHHQGDHGVVQVVLRVEGPLQDPDLLRLTRLLPCPAPSGSSPRVCWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TE63</accession>
    <name>A0A423TE63_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative testin isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_006788</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001855">
        <property type="protein sequence ID" value="ROT74701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TE63"/>
    <dbReference type="STRING" id="6689.A0A423TE63"/>
    <dbReference type="OrthoDB" id="10069167at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09340">
        <property type="entry name" value="LIM1_Testin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09341">
        <property type="entry name" value="LIM2_Testin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000005">
        <property type="entry name" value="Testin isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010442">
        <property type="entry name" value="PET_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047120">
        <property type="entry name" value="Pk/Esn/Tes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24211">
        <property type="entry name" value="LIM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24211:SF22">
        <property type="entry name" value="TESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06297">
        <property type="entry name" value="PET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51303">
        <property type="entry name" value="PET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PET" evidence="8">
        <location>
            <begin position="99"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="544"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="610"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="350"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="365"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="395"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT74701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="747" mass="82899" checksum="FE3A39A79B8AA810" modified="2019-05-08" version="1">MSAEVSSVRPNPYIFDIENRRKRRPRLAHEIGAGAKCKKCGDKCPGFELHFWRKLCMNCRCGIYDHEVEEDDEDIGKIVIGKLFDRPPRTKKEEMEYCHGNNLEMINEETGKAENVKFDWVPPNVEKSLASRYMALIPVEKRPIAGTEAAKERKRQLEQQLPLYDMDAAQRCDNLPPEELQSFHAYLERIKTQVAGQGMVQEIIGAPVSMAQPLQSQRKPGSSAPLMTGDIDANGNIGYQPDSSVGQMMPPGSHMPQDNIPGSQGQYRSPTGNQNDDQGNVNVNDPRYQFLGGMIEEPYLNVTSRPEDLVHSEAYGGKLGTSRPLTSLARNQPLDNVTAGMANLQVQPQGQGTEKGYIPGQEHIPGQPGYVPGQPGYKPGQPGSLPGQPGYTSGPAGSQPGQPSRLNLDMLKASQVNQDIFKASQVNPDMLKASQVNPDMLKASRVNLDILMASRDNLDILLASRVNQDILMVNQVNQDTWQASRINLDMFRGNQAPYGARVDTLTGGSSIAPGQDVNVLFPGESQIIGSQAGNTAPSGQKSKFSCQYCNLPMNVGDVAIFCERAGQDKCWHPACFCCFTCKELLADLIYFYKDGNVFCGRHFTDAAEIPRCKACDELIFGNSWTRADGFDWHIHHYSCYMCDLELAGQRYVPDKEGYPYCLPCYMACLAKMCEACEEKISPEMNRCGHRGYFYHASPQCFKCYSCKIPLMGKRFKMSKNWVFCSNECIEAAAEALAVNPNPKIKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THP0</accession>
    <name>A0A423THP0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001701">
        <property type="protein sequence ID" value="ROT76020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THP0"/>
    <dbReference type="STRING" id="6689.A0A423THP0"/>
    <dbReference type="OrthoDB" id="6351652at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="84"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="268"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="600"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="340"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="611"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="766" mass="85603" checksum="EDEC09D5BC18CA9D" modified="2019-05-08" version="1">MMDDDAAPRRAPPPRPSVLPQYNVPRPVVPEVSLMFDSEDSLIWQQPKSSLPASLQQKKDVPFTKAGSTVANQRIPVISAVNNPGKQAFAAGPPRDIQGSQSTTHFKNRTEENHPRPKLPLQSKAEGQFHREASGSPVLKNPIISEKHYNPLIYSPSQKNGVNKEVGHSSSPPVREISPLITRNTVPVTRVLTPQTQNTVSSPSYEDSAMLSKSSWPSQVTTKSVHFYKNPVMSDEETPLHLKRMEQHQRCLQMYGYEKENVKPYSPPISEGKTTEPSNFAQSYGKGLNMPPSLQHSSRLIPHGGQSSHRPFREDEVTHQSDHVSSRVSNQCDPSVYQLIEKQNEHIFRLQTSLEKLLEKQEHNEAQRNKESRELLREIVMATSANQQEKHKQIFKDTSSQTEPDKCETKSIGINTEISWADLIASVTPSENAVERGTEQGARFESREAGKVYQTNNRNSGERQADIIRDNYKAKSLNRRDSSSRQATNWTVHKEMSLTMQEVVMKTIEEDPPSPDPSVHISMTEYHDGSRHEEAHSGMRNPQKKSVDWEGSPVLGESASMCSPAAHDSPQHQEGAQATKSTGVTFYNNVMTNIQHILQNSKAAEEDERSEDAATHQRQRESNSATSEQETTVIDPQMEAVRKQLMQFGISFIDPATLATNNRPVLDTMYLPGLHNMLSMYQNSIPNSGPVPYQETDATAAKYLSDAQLAAIAAASPAMTGRTRAARETKALRPPFQQIKNADTENNFSIATKKFLGKYGLQEDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIG4</accession>
    <name>A0A423TIG4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Androgenic gland-specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005134</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIG4"/>
    <dbReference type="OrthoDB" id="6358465at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036645">
        <property type="entry name" value="Elafin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57256">
        <property type="entry name" value="Elafin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019228328" evidence="1">
        <location>
            <begin position="16"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="126" mass="13855" checksum="50E2379F6AF2D6B1" modified="2019-05-08" version="1">MRVIVLALLVAASSACRYYCKTLSDETYCCDGGKDYNPPEYHDGNCPKVRSFCPRIEGGSRRPDVCPHDGACQPYEKCCFDTCLDHHTCKLADEPSSTATPTLTTPTTKPPYVIANFARNKVNRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TIK1</accession>
    <name>A0A423TIK1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Vacuolar-sorting protein SNF8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_005175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TIK1"/>
    <dbReference type="STRING" id="6689.A0A423TIK1"/>
    <dbReference type="OrthoDB" id="283883at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000085">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017215">
        <property type="entry name" value="ESCRT2_Vps22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR017215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT76281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="244" mass="27641" checksum="18EA9C7C06D6E74A" modified="2019-05-08" version="1">MRRRAGVGAIQRQKIQQDKFKEKGSEIQENQLEQMTLQMEKFRENLEDFAAKHKNEIKKNPQFRKQFQEMCASIGVDPLASGKGFWCEMLGVGDFYYELGVQIVELCVATSHRNGGVLSMDEVLRKLNQRRRQDNQISADDVIRAVKKLRVLGSGMEVVASGSSQFIYSIPGELSMDHTTLLQQAEKAGHLTVASTASSLGWTNERVGRTLDHLLRVGVAWRDDQDRPASYWFPAFFQQCAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TKV0</accession>
    <name>A0A423TKV0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Zinc finger protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_004304</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001570">
        <property type="protein sequence ID" value="ROT77065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TKV0"/>
    <dbReference type="OrthoDB" id="6349934at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000075">
        <property type="entry name" value="Putative zinc finger protein 536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050888">
        <property type="entry name" value="ZnF_C2H2-type_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="868"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="896"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="925"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="984"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1012"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1042"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1071"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="58"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="185"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="261"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="350"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="805"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="810"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT77065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1147" mass="127719" checksum="3B36101C9E8C83EE" modified="2019-05-08" version="1">MGSIGCPLCCRQDFMSVVALHEHLLYYIYRPLRCAVCGSNAGGIQGLIHHLAQHLGDNPAGGAAKEGGPPPPPPEMKRDQRAGAPPEATAVPLENGAGDKDFLCASESSSRSHWSQNPDGGNLAGRDEPVELTLRAYFCHCCGAKVVGKDKYFFHIKQHNTLLNSSSMPEAPSIVLSAPQSVSCESDAAPGSHYTSASTTPVNVGIDADTLTGDELDPLDRGFPDAKDAATSAYMEENDTATQLLKLREWQLEKHGKRFKRQRLSFAKSPASSDRSPMSGRQRNSNSSPGVSKQKSGRLSQNSEPCSYSLEKQPLSQISYASSNDPYASVTPQTNASTIDELQYMCAPAVDRGTESESESRKDLEESPGTFKTPEVRHVENNQRLESKPHFDNSYASSSTVQLQTPGLQFEAASSTDQEPEPVSGSEKESCVYDNPQVMSLKPSDVESQQDPSLSRIDPDITRALENGDQLQPEDQSVLHTQNFQTHPVLYTPAATDFESTSERELEQCQQDGLDDCFQVNANLTDSLRTLSESPNCGANSEVDIESSILVADSWIAPHGSAQYLELVPAFKSQGSLEQESCRSMAQEDVFTRQPTALRRPESSEVAGNLNSLEECRTVAQPAQNYLQTYDEPVLESGNVSVDPLRNDGEEQSIQDLHANAASSCHQLPETASVTSATSTKTPSTDIPQTAPAMEIVHEAVHEAEDFPQEDNYPNITREEPSNYYQDYPAKPSESDVCENEILPDYSAYPLPYLHKKFHHDQERKVAQSSGGGQNADLRRYIHNFQSLLVSRLNASFSTDVVLKTGGEDLGSDEGETEDQPTEDVEPAGSQRLQQSEHVCEVCKLECTDEAQLNMHYRTHEQGDQKNFACRFCKNSFFMKSTRDRHERKHKGKKIYRCSQCQQVFNKAYILTRHRREVHAVKRPFKCDECDKDFTTSRNLQNHVGVHRAEKNHKCTHCEHTCRTASGLRTHVMEAHMASRDRSFSCQECGEKFSKHYGLKRHMERKHGDGRVPCSVCSRLFSCKEDLIKHSKSHEDKSKDDLSCSFCNQTFTSTWSLQRHTKKHQSESRQFKCSKCPKSFTRKDSLLSHEKLHTQKKNYVWDNCQRPPASSSNCIDILTIVGWRPSVLCQSPLRPLPLGRPPRLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLQ0</accession>
    <name>A0A423TLQ0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcium-activated chloride channel N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_004000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLQ0"/>
    <dbReference type="STRING" id="6689.A0A423TLQ0"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013642">
        <property type="entry name" value="CLCA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08434">
        <property type="entry name" value="CLCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019502685" description="Calcium-activated chloride channel N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated chloride channel N-terminal" evidence="3">
        <location>
            <begin position="25"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="200" mass="21771" checksum="25BC2A05D33AD568" modified="2019-05-08" version="1">MLPYAKAFLSLVVLLQVLTRAEAEVALVNNVYEGLVVALDPKLPASTEADQQTIIDSVQDLLTKASAAIHAATDTRARLGQVTIVLPRSWAVAADADASGRESWSDAQVRVVAEGRFGNVPRAEQGGRCGVPGSRVEVPVQFAQDLTIQARYGSAGKVMAQEWLKYRYGVFEEHGYPGDGRPHVPRRAEQYDAGHRLHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRT4</accession>
    <name>A0A423TRT4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002111</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001282">
        <property type="protein sequence ID" value="ROT79162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRT4"/>
    <dbReference type="STRING" id="6689.A0A423TRT4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="525" mass="54996" checksum="00F22C3B7DAE81D5" modified="2019-05-08" version="1">MRIQHRHVRTGHRHAKQKNRKKTGERPRPRRRGHGAFPPSPAAEATAPSLPAPLPRPRRPPSQPRCRGHGAARPRRLPSQPRCRGHGSPAAEGASLPAPRATARPLSLPAPRRGLPCRGHGAFPPSPAAEATAPAATARPARPRRLPSRCRGQAAAEATAPSLPAPLPRPRRPSLPAPLPSHGAFPPSCRGHGALPPSPAAEATALPRPRRLPSQPRCRGRQPGHGAACPLPRPRRPCRGHGASLQPRCRGHGAFPPSPLRGAFPPSPAARPRRLPSQPRCRGHGALPPSPAAEATAPSPAPLPRPRRLPSQPAAEATAPSSSPAAHGASSQPRCRGTAPSLPARCRGLPSQPRCEATAPSLPAPLPRPRRLPPSPAAEATAPSLPARCRGHGAFPPSPAAEATAPPSQPRCRGHGALPPAPLGHGAAAEQQDRERRAVSPPLTLQFRHNGVAESDLGKVLAEGGRGVALADVVARARASHAGRLPRDFHLASRPWVHPQGRGAGVPHLRHPGTRVCEGREEIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TSF7</accession>
    <name>A0A423TSF7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Fibroblast growth factor receptor</fullName>
            <ecNumber evidence="19">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">C7M84_001920</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="28 29" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="28">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Receptor for basic fibroblast growth factor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 19">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.10.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="19"/>
    <dbReference type="EMBL" id="QCYY01001254">
        <property type="protein sequence ID" value="ROT79362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TSF7"/>
    <dbReference type="STRING" id="6689.A0A423TSF7"/>
    <dbReference type="OrthoDB" id="535945at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043235">
        <property type="term" value="C:receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005007">
        <property type="term" value="F:fibroblast growth factor receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008284">
        <property type="term" value="P:positive regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000007">
        <property type="entry name" value="Fibroblast growth factor receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000016">
        <property type="entry name" value="Fibroblast growth factor receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000593">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016248">
        <property type="entry name" value="FGF_rcpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050122">
        <property type="entry name" value="RTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020635">
        <property type="entry name" value="Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416:SF550">
        <property type="entry name" value="FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24416">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000628">
        <property type="entry name" value="FGFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00219">
        <property type="entry name" value="TyrKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13 22" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="16" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="8 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 19 25" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 19 23" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14 19 28" id="KW-0675">Receptor</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 25" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12 19" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="27">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="27">
        <location>
            <begin position="141"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="27">
        <location>
            <begin position="235"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="27">
        <location>
            <begin position="340"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="26">
        <location>
            <begin position="585"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="24">
        <location>
            <begin position="873"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="24">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="20">
        <location>
            <position position="726"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="591"/>
            <end position="597"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="619"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <begin position="667"/>
            <end position="669"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="673"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="730"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="744"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="22">
        <location>
            <begin position="35"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="22">
        <location>
            <begin position="163"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="22">
        <location>
            <begin position="256"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00056965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR000628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR000628-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR000628-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000628-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="ROT79362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="897" mass="100774" checksum="2A78E73F201AA0DC" modified="2019-05-08" version="1">MGFTKEDYDHDSGGDATSASTQRLAKVGENIRLKCKPKVDYKVHRVVDFTWFFNDQVFEPGADPRVKMSDNKERARLRLNDVRHEDEGRYACRWNGSQSQGWVNYTLLVSEDIPISTMPQALHADSKVLVPDAEDLDSPKPKFIKDLKPLLIKPAGNVAELKCQASGENLNITWLKYGAKPTRQYGDVRIKGSTLKMEDLVPTDSGQYTCIVSNEHGSINHTYTLEVIERLPSRPIINKELSNRTVVQGSKTTLQCSVISDQVPYITWLKHTTRDNGIDSQGKGHPPFSVLLRRLYGAPFCVCGMHGTVETQYFKTRFLLEVTVLPFLLFSFLEHVGSRPIFTKKLKNMTVISGSTVRLEVGIYTKNTPSAYIVWRTGLPQLDPDVDFGSREIYINETILKAASEGQCGNKANPLSVAQGGGNITSTEDPQVVVLTNVTEKDAGWYTCIAANSLGYSSSTAYLNVIDAEPILADAQSHVVPILAAVFVVALAGVGLILYCFCKKWKKEKRRAKELERAKEVITQQWIKKVIVERQNSDASQEPLIVPTIKIERCQSNSHNGSENTRISEYELPLDILWELPRSKLIMGESLGEGAFGKVVKAEVQGINRPDLTTTVAVKMLKEGHTDAELMDLVSEMEMMKMIGTHINIINLLGCCTQDGPLYVVVEYAAHGNLRDYLRNKRPSSGYERAIGQETNALTERDLVSFSYQVARGMEYLASKKCIHRDLAARNVLVSKDGIMKIADFGLARDIHSQDYYRKTSEGRLPVKWMAPEALFHRVYTSQSDVWAFGILLWEIMTLGGTPYPSVPSVEKLFQLLREGHRMEKPSNCSLEIYTIMRECWRYQPTQRPTFKELVEDLDRILTLSSTEDYIDFSTPQLDTPPNSCDSSHTSDVLTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTP3</accession>
    <name>A0A423TTP3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ZP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_001483</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001187">
        <property type="protein sequence ID" value="ROT79792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTP3"/>
    <dbReference type="STRING" id="6689.A0A423TTP3"/>
    <dbReference type="OrthoDB" id="5867217at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052774">
        <property type="entry name" value="Celegans_DevNeuronal_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056953">
        <property type="entry name" value="CUT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001507">
        <property type="entry name" value="ZP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327">
        <property type="entry name" value="FI18240P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47327:SF2">
        <property type="entry name" value="FI18240P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25057">
        <property type="entry name" value="CUT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00473">
        <property type="entry name" value="PAN_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00241">
        <property type="entry name" value="ZP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51034">
        <property type="entry name" value="ZP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="71"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="ZP" evidence="3">
        <location>
            <begin position="158"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT79792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="63895" checksum="1A5FE0A0EA006489" modified="2019-05-08" version="1">MLITIPAHRLVDLALTPVLSSPRSANFNNATGDCQISDMDRHTTVGTGAFKVAENSDFLENNCVDDPVRLCEFQRMEGRILKTVDSVFQDVESLEDCKRLCLTAPFRCYSFDFGDTGDKVCRLSHHSAATLTHIEEPYLEIAETATYELSSCYNVTIDCRSGDMVAKIKTSKIFNGKIYAKGSPNTCVNDIENALEFELQMTYNDIDCDVERDSASRYSNDVVIQHHDMIVTSADLGLRVHCQYDLTNKSVSNRVDLNVEEDLSPVMEEGSTVDSPNVIMRVTNRNGDDISDASVGDMLQLRFEIVDRNSPYEIFVRDLVAMDGGNTKNLTLLDGRGCPTEISIMRPLLKVDSTGKVLGATFDAFKFPTSDVVQFRALVTPCLPTCEPVVCDVMDFGGQVKQAESYGRKKRAISHMTMGDTALASPFSQDYTIISPYSMSVVSHPLQRVRREAEQEIPEELLVVQSIKISDKFAFRGAQTQSRDSAANSNRKETVTATDGDPELVLQEDVSGVCINMVGLVLACSVFLVAQLVIIVAWTAVWHRRRRSKLEEPLSPATTTESLRQLYDSGYPRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTQ6</accession>
    <name>A0A423TTQ6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hemicentin-2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_001436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001185">
        <property type="protein sequence ID" value="ROT79812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTQ6"/>
    <dbReference type="OrthoDB" id="8825892at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278:SF32">
        <property type="entry name" value="NEUROMUSCULIN, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23278">
        <property type="entry name" value="SIDESTEP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019226872" evidence="1">
        <location>
            <begin position="18"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Immunoglobulin" evidence="2">
        <location>
            <begin position="35"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT79812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="184" mass="20965" checksum="9CD2A3AFC8FA3FE2" modified="2019-05-08" version="1">MCVSMSWLLHWTFTLRADGKLRSSAVRCMRERRPLTEVWGVVGGKVLLPCDMNPPLQNDSTHLVLFYHGALGTPIYSLDSRGKSLEHASHWAEQDLGHRAVMRVNRKQHGLLLEDIQLKDQGMYRCRVDFVESPTRNVRVRLRVVVPPTCVGQQQLTYGAARHETLEVPCQVKAHPMPRLLPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU78</accession>
    <name>A0A423TU78_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_001286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001167">
        <property type="protein sequence ID" value="ROT80014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU78"/>
    <dbReference type="OrthoDB" id="10056177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="33"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="609" mass="68694" checksum="DA581698BB42CA95" modified="2019-05-08" version="1">MAPQENSNEPPREWRGWGHWLKQEFTIDKRFIPIKCIIFFFTGGVVAFIPYLTLHMQQLGLNVEEIAIMYAVLPIASLLGPPATGMIADKFGKYNIMFIINIILTGVFHTLMLQVPPVPGNAVTFECDTGGHSLVWEQCDDCYDLRNNTDAALTIRFCKYECENAPEDVQLCLSNAFTTTCNSYNATDKIKINGTLFAPWMEEGQQCFHTWREIDFEGNVYNNLTCNSPCPMKCQVFGEKTCHEMLDKNAPPMTFWSYFVLRLIATFFLGSSFTMMDAVTLAQINKQGGEFGKQRVMTMVGFSIIPLIAGIIIDRIGEKTGVIDYMPAFYLGDALLLLAVFLVSRLPLEVELPEESLTKGLKEIITRVEIDIFMILILIMGTNYGFIESYLFVYLKELNAPNYLLGLTMTTGCMISIPMLFWADPIVDKMGRHNVFLVSFLAYAVRMFGYAYITNPWMCFPFETLEVFTYQLMWVAAATYCPILAPKGLLATMTGMAGAMHYSFGKGLGAFAGGYLIASLNTAGAFKVFGGVALFGAVFYFLIHHCYMKKLVEKREKEYEITKAEEDSKVSELEVMQSKDRRVSRVSTYSRKSSVDQNGRRLSVVDVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVP1</accession>
    <name>A0A423TVP1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative nucleobindin-2 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000753</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001113">
        <property type="protein sequence ID" value="ROT80517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVP1"/>
    <dbReference type="OrthoDB" id="5982823at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="295" mass="32196" checksum="0CED83965ADE73F2" modified="2019-05-08" version="1">MTNQSALRNLDKEVFEEFLEQTKKSEFEQDGGWQGLDEQEVFSQQEYEEFERRRQEEIRQLVESGVIPPPPGYHGMPPPQPAMYQGGPHPGLHPAAQGILPPQAVPQYGVPPQVHPNAVPPQVHANAVPHGYQAVPQGYQAVPQGYQAVPQGYQAVPQGQVPPQQVQYIPHGAPYQAPAQPQAQQPVLSQPQVQQPVQGQPQVQQPIQGQAQVPAQQPIQGQPQPIQGQLQAQQPVQGQPPAQQPLQGQHQEQQPIQVQAQGQQPLQGQQPQPVAGQPPNHQPIQPVAAHPAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYQ2</accession>
    <name>A0A423TYQ2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein FRG1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_025261</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Cajal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FRG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000951">
        <property type="protein sequence ID" value="ROT81588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYQ2"/>
    <dbReference type="STRING" id="6689.A0A423TYQ2"/>
    <dbReference type="OrthoDB" id="5539371at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055120">
        <property type="term" value="C:striated muscle dense body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007517">
        <property type="term" value="P:muscle organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23338">
        <property type="entry name" value="beta-trefoil_FSCN_FRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.80.10.50:FF:000061">
        <property type="entry name" value="Protein FRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008999">
        <property type="entry name" value="Actin-crosslinking"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013865">
        <property type="entry name" value="FAM32A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010414">
        <property type="entry name" value="FRG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928">
        <property type="entry name" value="FRG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12928:SF0">
        <property type="entry name" value="FSHD REGION GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08555">
        <property type="entry name" value="FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06229">
        <property type="entry name" value="FRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50405">
        <property type="entry name" value="Actin-crosslinking proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0517">Myogenesis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT81588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="28758" checksum="C1395E8D7A51FE1F" modified="2019-05-08" version="1">MSEYSKVKIGKLKLKGEKSRKKHKSKKRKAEEGDGGSSSTSTHESDKADHGGWWSITALHQISGSVAVQLGGAPIYVRALDNGLFTAGAPHDQGDGPSPEEVLTAVPAGDDRIAFKSGYNKYLGVDGAGRVVGRADAIGPREMWQPVFQEGKTALLAANDCFLGIDDDDNVVAVSTTAGPDQMVNIRSSTLRECDKPKEIPEEERGKLLDVEVNYVKKFQKFQDKRLKINKCAELRSARSEGKLHETLLDRRQKMKADRYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZW8</accession>
    <name>A0A423TZW8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative ATP-binding cassette sub-family A member 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_024833</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000897">
        <property type="protein sequence ID" value="ROT82003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6363921at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000335">
        <property type="entry name" value="ATP binding cassette subfamily A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001253">
        <property type="entry name" value="ATP-binding cassette protein subfamily A, member 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF36">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="520"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="562"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="625"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="702"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1194"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1472"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1506"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1537"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1584"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1638"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="790"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1703"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1333"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="2012"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="2046"/>
            <end position="2057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="2068"/>
            <end position="2082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="2118"/>
            <end position="2127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT82003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="2127" mass="233792" checksum="36F14C281EF188A4" modified="2019-05-08" version="1">MEELFQAIQAMGAVAFSEKILQNVNHTYLLSEIDKLRIEALLTSSWLTAVTTYMTDAVSSLSDLSQLGAVMDISKIISGEVDPVSFLTGSVQLLQMQMWENLGNSFLGILSQGADIISGSKLEDDLMQVVKGIAGLQAASNLGTMDFTIPTTAMITNWTSMAEYLTEELDIEELVVEALSRSELNLMAVLSLEDLTLEEVICEAKQVVRVVTLAEDSPVTPANLSASLCHSSDAEALAATFLQHLNLGPLVQTLTKFGINATLASRGTTLDQLVKDMATLSTVSKGLPNMASTFSALRGIMDTLRQDAAELNQQEKQAGLLGNSTTGSVLGELSCKTMEFPDILDVGERLMACMNLQRFQAVATEEDMLREANLVVDTYGFLAGVVFEGVGKTGDTAKTVPAKLKYAIRVDYEKTPSTFNLGPRYWRPGPYSNMAVHMRYHQGFLLLQEMMDSAILRLQYWTNNPQDAESVPRAKRQATAKGVSDAERDMLLNLPVYTKQQPYPCYEKDEFLVMMNESPVMSLVFSFVVFTVYVVFLIRHLIQERQSRNKQVQEVMGLRTWVDLLAWLFFSLLLLVVILLALALLIKFGNLQPKAEFGVLLAFLLSYGLSIVSFCYLVSCVVPGAILGVFVGVMALLVFNVPFISISVVQAHTPLHAPLQSLLPPTAFGFGFRVICQYELLQIGATFGNLWTPPLRDTDMTLGLAIVMLLADTLISFVLAVVISILKNGTLRALATGGRPPLLHQASFSDKASLKRSNDFTFNIFHEDTVHPLDVDPGLKQSFKKGLSIVGLRRIYENRGASKVAVDNLNLELYEGQIMALLGHNGAGKTTVISMITRELRQTAGNISVYGHDIRTSWDKARKLMGMCPQKAVLFPLMTVRETLAYYTRLKGTAADQTDAEVNSTLINMGLYDHRDHLGRQLSEGLRRRLCMSIAFVGGSKLVILDEPTSGVDPAARAAMWEVISNHRSGRTILLTTHHLDEAETLADRVAILHQGRLLCVGSPLALKSEYGSGYSITLSNRRVYDETEDGQYKGKHGKDGSFLPLDVSFQFAKTDAVLELVKRYAPNARLLEAVNGEVTYSIPMTDGQGNESRLPELLGELEGKLEELGFVSMEIRPTSLEDVIIALNAINAIESESLAQSKVPRAPDGLAEEEDLRDLFNFRPLAPRSGVRLSFQRLLALLLKRLLHHGRDWVFYIQMFVLPLVFICLAMLGSWCRPAFEGTAPLEMSPHIYSAPSTSFVRQLDPTFEPLAEEFLRLTLGASSSSSSTGQWSACPPSVANASLGVPHCNISGDSTQSLCRCEDDVCSVDVTNQPSLNDWILGTRYKHVQNRYGAEPGRGGPPRSHPAAPESAYDNSRLLRPSPPPYLNALTNARLSRDFSGPVQGHHHHKPGQVLQIRLEQHLTVASQQHVADLGIGPPDPGGAQRWSARSTAATVGERADDAASLLRRRRVEEHLLDANMIGTSRHYTLVATLTCILLINIFFTVVVLIIFNQQQFVSHSNLGAFFLLALLYGLSILPIFYLTEGLFRSETAAVFSFFCGTFSIGLISTLLLIVCEVYTWVKELKYDIGSSFLVLNDMENVIRYLFLIFPPFTFACGIKSLAVSYTKTSIMARFGIDIYTSPFSWDPSMQGGLGIHYLALAIWAVAGVVLLHGWNSCVGPLSRPAASAPKATAGAEEDKDVAAERIKIQCGGASLYDTVLRMVGLGRDFASPPTSAVSSLYLALKRGECFSLLGLNGAGKTTTFRCLTGDLRPSRGQILINGIVLNEALSLPRPVMSYCPQNDPLDPNITPREALFIMALVRGFRDEELVENVDRAIKQLGLTNHEHSYIRYLSGGTMRKVSLALALIGNPPLVLLDEPTTGMDPASRRIVWRAVQSVTQDGRTVLLTSHSMDEVNHLSHRMAIMVNGYLVCMGSPHYLKYKLGDKYTIRVKAKDIEDLPVIVDYLRGQLNEVLLKEQHHLSLVAEVSRRLPLRLVFDTLDSAKLVGVTEYDVSQTTLNEVFRLLTSYQGDGQVPPSPTDSEADQTSVPMHLPNLSPAGVNVPDSTFQSPSRSPYLSPEPALTPDGRRSMYDNVEDGRVETYATVGRLSAKKAPTPEVTALERDSPTSQASTADDSPEEEWTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0E9</accession>
    <name>A0A423U0E9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000878">
        <property type="protein sequence ID" value="ROT82144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0E9"/>
    <dbReference type="STRING" id="6689.A0A423U0E9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="43906" checksum="68CA95DD945CFFE8" modified="2019-05-08" version="1">MTASPPKEGLTPGLSFPTNPRSHPSSPTFFLTACRHPEPPLRLTWAILLPLPLSLFRASRPLSCFFSLSLTNHRSLTSPHLPPPPTSPTPPPPLLLPLPNHLLSHASPLLPQPPLPLFSLSPKYIPFLSLLPISHPQPPPPLPASSPPLPNHLPLTFPPLPPTTPLSRHFSPSPNNLPLHFSPPPQPSIFPPPTPLPLISPNPPPTPPILPLLSPKYSLSLFLHRLSSLHFLSFRALSLFPTLFRLPLSLFLFLASFSLYLSSSSLSPSLIYLSIISLLLSLSLSLSPPSLSLPPPPPHPLLPPPPPPPSHPPHPSPPPSTPNPSPPTLTPLQPLPPSCHHPHLLSSTPSTPPSTPHPLSSPSPPHPLSPSLSPLPSLPSASHLSHPPHSPYSHPIPLPLTLLADRVNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5B8</accession>
    <name>A0A423U5B8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000629">
        <property type="protein sequence ID" value="ROT83886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5B8"/>
    <dbReference type="STRING" id="6689.A0A423U5B8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="389" mass="39746" checksum="E45B90B70E2EE1C2" modified="2019-05-08" version="1">MRTSTSILFRLSAGFPFFPCRGLRSPSPLPALCPVLPAALATAAPTPSLVPPATPCLLPVPSFPDAPCCPASRSPVSPAALSRSPAVPCLLPPCSPFPVPLLFPCCSLASPSRPLLSPAAPSRPLLSPALPPVPLLVPCCSLLLPPVPLLSCAPSVPVCPLLFPPVPCCPLLLPAASLPSLAVPLTASSHHITQKKETLSPFPDPLLSPAASSRPCCSLLFPPSLAVPCCLPASPSRSPCLSPAGFLGPPAAPSVSLLSPGLLLLVPCCPLTAPAAFPPVPCCPLLLLLPPVPGSPATPLPSPSCPLACSLPSPAVPCCSLASPSRPPPAVPCAPCFSLHLYSHLIRNININGAYHSTPLPLLSPPPSLIIWITRPQYSHSLTSYVTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U5Y6</accession>
    <name>A0A423U5Y6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ATP-dependent RNA helicase YTHDC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_022725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000596">
        <property type="protein sequence ID" value="ROT84085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U5Y6"/>
    <dbReference type="STRING" id="6689.A0A423U5Y6"/>
    <dbReference type="OrthoDB" id="6103986at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000008">
        <property type="entry name" value="probable ATP-dependent RNA helicase YTHDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF213">
        <property type="entry name" value="3'-5' RNA HELICASE YTHDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="102"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="760"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT84085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="803" mass="89396" checksum="AC5641A6B1240E64" modified="2019-05-08" version="1">MDCLAEQVLPPSASSQLKSGEHSFPDSARAFLVEAIRTLQHRLYELRNELEGEHLPHGLVLLLQQEDQFQRAKHKEKLHCICSMSRWSKAGRNDLREHVLQTRISALTTAERVAAERGEKVGYTVGYQIRLESKLSPKTLLTFCTNGVLLRTLMGGDSSLASVTHILVDEVHERDRFTDFLLLVLRDCLHKFRHLKLILMSAALDVNLYAKYFNNCPVIDVPGSTPVKEYFLEDVLKYTSYQTPEMLKAYKELEQRQSGQKTAAAWTQQMSQQTLSLGSSAPAPEPRSNIINSEFSKGTGAELDNTLKEEMDKCIQEAFLTGADEAFSQMMYLIMSENVSPDYQHSETWATALMVASGRGRVDIVEQLLALGSSLTLRAANDWTAADWAQSTGQQETLDLLHAYSACEGVDLLTISGKGMQSSSSSSNHGNVIRGPSTVVPLTELSPEEKRMLDAYHHSVSEEVADVDLVYALCYKIHTSQPPGAILIFLPGYDDIVNLRDRIIAEEKQYLIGGRDVSFDSNLGVSCLRCVWISQASSQQRRGRAGRCQPGICYHLFSRSRYNNMQHFQTPEILRTPLQELCLHTKLLAPANMPIADFLARAPEAPAFMVIRNAVQLLKSMDALDGWEDVTELGHHLLDLPLPPRLAKMVITATVLKCLDPVLTVAACLSYKDPFILPKHPNEKRSATAVRRKFTSGTYSDHMVLLKAFQAWQKACSEGWERGWCERNFVSGANMEMIHGMRSQVLAQLRGAGFVRARGPGDIRSKRAHERAGGERNLPSGVTTLSTTSRVTLTLGAATQLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7I8</accession>
    <name>A0A423U7I8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alpha-(1,6)-fucosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_022182</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000517">
        <property type="protein sequence ID" value="ROT84639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7I8"/>
    <dbReference type="STRING" id="6689.A0A423U7I8"/>
    <dbReference type="OrthoDB" id="2014825at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046921">
        <property type="term" value="F:alpha-(1-&gt;6)-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11300">
        <property type="entry name" value="Fut8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045573">
        <property type="entry name" value="Fut8_N_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027350">
        <property type="entry name" value="GT23_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132">
        <property type="entry name" value="ALPHA- 1,6 -FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13132:SF29">
        <property type="entry name" value="ALPHA-(1,6)-FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19745">
        <property type="entry name" value="FUT8_N_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51659">
        <property type="entry name" value="GT23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GT23" evidence="7">
        <location>
            <begin position="117"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="411"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for donor substrate binding" evidence="5">
        <location>
            <begin position="274"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT84639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="496" mass="58060" checksum="A1A5E32A1C4CDEAB" modified="2019-05-08" version="1" fragment="single">FHSRWHGNTGEYSGRDRKCQGTEPSLEFEQMRRRVASDVAYTWQYIRYHLTHGNSSGVSLEVVLEDLDHHFRVTSHDLTQLSKVDGLQEWRKKESAALSALVQHRLRVLQNPSDCASAKKIYCDFKAGGRGIGSHLHHLSCCFLASYGTQRTLILNTDNYNGNPRGLTALFLPLSDTCTSYNRSQMVPWPGKEDSLLVKFPDWDQPHPRPSYLPRSIPKDFSERLMRLHGDPFAWWLGQFFNYTMRMNEEFREYMANLTKEIEYESPIVGIHIRRTDKLSREARYIHLEKYMERVKLFYQELALTQQLTERRVFLATDDSRVIGEFKEKYPEYKLVYNRASINSARLSERRKGPNLGFFMADVFFLSHSDYLVCGMTSNVCRLAYELMQSIHPDASTRAWSVDSPLYFDFQSPHFVRARFSHTPRRNEEMELQEGDMIKTWALHFSKHHNPKDGFLYGTNNRTQKAGLYPAYKTIDILDKADIQSFERIDEKNARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9B0</accession>
    <name>A0A423U9B0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMAUG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000334">
        <property type="protein sequence ID" value="ROT85286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9B0"/>
    <dbReference type="STRING" id="6689.A0A423U9B0"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030371">
        <property type="term" value="F:translation repressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09557">
        <property type="entry name" value="SAM_Smaug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.170">
        <property type="entry name" value="Smaug, PHAT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037093">
        <property type="entry name" value="PHAT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037634">
        <property type="entry name" value="Smaug_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00536">
        <property type="entry name" value="SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAM" evidence="7">
        <location>
            <begin position="43"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="288"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="400" mass="43156" checksum="3AEF841AF1536517" modified="2019-05-08" version="1">MSWCGGGASAAVGAPGDAPQSPNNSATSSRSSGCDSNTEEPCQPHPGMRDVGVWLKSLRLHKYSPLLCNLTYEELLALDEATLESQGVTKGARHKIVLSIAKLKERHKQLVQIEKEVMNGGNLFCCLNDLKSIILTPFPPYTPPTDKGQPPPPPHSQGDEREALKEERCEASRPAVEGDGGSSIPEDDLPSQFTRVMGKVCTQLLVSVRPEDECVTAFLGLVEKCVNHEAFTLAQTRRLQSWKQQIIRVWHPLPPKTKDSRHTRRLPGLPSLGVGGLLSPQQFLAKRPSLQETPSEQLRPHITLQRTRSAPSRPHQLPLSGHARSVPPPTTSLAPGTSACSDLRLSGASGTSGTVLEPHFSPATSYSHLGPPPSSPDPADNDITDRLESLCLSVTEHALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA82</accession>
    <name>A0A423UA82_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative helicase SKI2W-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000238">
        <property type="protein sequence ID" value="ROT85595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA82"/>
    <dbReference type="STRING" id="6689.A0A423UA82"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055087">
        <property type="term" value="C:Ski complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070478">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000001">
        <property type="entry name" value="Ski2 ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-dependent RNA helicase Ski2/MTR4 C-terminal" evidence="6">
        <location>
            <begin position="195"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="42505" checksum="14323E71326A30AC" modified="2019-05-08" version="1">MIVFVLKEKSRQNYSKHELMAKEALSASEAMFDPLEEPSEHGFLEIAFKHIAAITERVVKIDGDKVIDNIKKRQIPRFKDDPPSQSVMELLKEMQRLNESGGENLACLDPLNDLGIREIAAVSNIHRMNILRKKAVEMPCLDCTQFKEHFNMMYKKLHLREEIGRLKFLMSEEALQLHPEYQMRIQVLKTLGYIEENNTVTLKGRVACEMGNHELMITELVLENVFAESPVEIISGLLSSLVFQDRNSSDPELTPELLKGVKQFKEVAKRIGEVQKECGLKEAVGDYVDQFNFGLTEVVFQWAKGMAFKKIMELTDVQEGITVKCIQRLNEVLKDVRNAARIIGDPSLMQKMEEASTAIKRDIVFTPSLYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRI4</accession>
    <name>A0A3R7LRI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004438">
        <property type="protein sequence ID" value="ROT60988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRI4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="388" mass="41076" checksum="36A15AB42B0B95F2" modified="2019-04-10" version="1">MRNRAIPTRRLLVSLTLPWPLSCILSAISSTSSAFSLSALIPSSVSSLLVYSSPLFCLPSLLLSFSCLLPSCCISLSSSFSPSLLLSPICLLTQPPYRSASDLSSSPISVLSTNYLLSLPLCSLSLSPLVPLHCSLLLSASPSSAFAPLSALSLLSASSPLSAASVPLYSSFPSSSLSSPLLLPPLQLLSSSCALYIVSSLTLCLAQLSDSLSPLSAVYWPPSTPSSTPLYEPSALSVLLCVIIMVLLLRAWYLALSTLSPLLCSAASLPFSLFCSLRLAGSRGTTNHCSLLRIPTGSPASISLIFEPLWFCVLFLLCSLPPLASLDFSVPHSTPHSCSHQTSVCFSSSSCSLPSSLVLLLRSLSASYLRRDKQLRSHRLSPRLLLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LS98</accession>
    <name>A0A3R7LS98_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_020588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004080">
        <property type="protein sequence ID" value="ROT61614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LS98"/>
    <dbReference type="OrthoDB" id="6349261at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="593"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="620"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="642"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT61614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="699" mass="76830" checksum="AE950722A909A409" modified="2019-04-10" version="1">MDHQSLPNVTAGTLSPALHPSQGVKHELTSVVDLQPVDTGMRSMSSEMQPVDEDLQHVAQDIHQVSRQIHQVNSGIPVEELRLTEGNMQSVSDEQVDPLGVTNEDTLTMDGEMGDMEQNQDVQVIAHQANLLEDASGVISSDKTIKLPGFSSQQAPHEGHDPHDLQLSSITSGAGTLPLDAQHYYESLHPAPIMVYEVPAGNIVPFDSLVSVPLGKSIGEKNNEGVDLLQASVSETVYAHQSQDMSHPLYVLHQPQKKEDSSEGMVIEQINSNDGVSPNIVLENRDANSFNKVEGHSSGMMPIGSEFSLISTSCYDSSVTTVANMAHLSMSAVYHSSTDTDSEVALTLASLGNPKNEKMERDCVQAQNTEPADVIRAASIISGVTQHQQFDNIHHQPNNTLEDQMGKKDQKSTLNESQKENLLGQLLKASEHCEPATLIPEGVVDDVIPAVGYRIMDMTNLSEMIKMMHRCTGSMGAIVIQEQASLREGAVSQLSVICTGCQEGAVCATSNRTLATGPWDINARVEQLTKEFNIKEDQVQRMLEILGIFYRPCDPSLQPIAQTMEMEAAPVPPPKKKRKKKSDTDSSGKPKNLVCTVCKERFVGENHLKKHMHSHDLSLHTCPYCHAYFKKPFNLKQHIKKHESLPQPPTQHPDDNTPGREYHTLEAAAPNDDATNQQTLNMFHVSDVEGQQQGMFQYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTL5</accession>
    <name>A0A3R7LTL5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha N-terminal protein methyltransferase 1</fullName>
            <ecNumber evidence="5">2.1.1.244</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">X-Pro-Lys N-terminal protein methyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_019609</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54712"/>
            <dbReference type="Rhea" id="RHEA-COMP:13785"/>
            <dbReference type="Rhea" id="RHEA-COMP:13971"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138057"/>
            <dbReference type="ChEBI" id="CHEBI:138315"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine = N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54736"/>
            <dbReference type="Rhea" id="RHEA-COMP:13787"/>
            <dbReference type="Rhea" id="RHEA-COMP:13974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138059"/>
            <dbReference type="ChEBI" id="CHEBI:138318"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:54724"/>
            <dbReference type="Rhea" id="RHEA-COMP:13789"/>
            <dbReference type="Rhea" id="RHEA-COMP:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:138061"/>
            <dbReference type="ChEBI" id="CHEBI:138317"/>
            <dbReference type="EC" id="2.1.1.244"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. NTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.244" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01003637">
        <property type="protein sequence ID" value="ROT62543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTL5"/>
    <dbReference type="STRING" id="6689.A0A3R7LTL5"/>
    <dbReference type="OrthoDB" id="1298661at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071885">
        <property type="term" value="F:N-terminal protein N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000025">
        <property type="entry name" value="N-terminal Xaa-Pro-Lys N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008576">
        <property type="entry name" value="MeTrfase_NTM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753">
        <property type="entry name" value="AD-003 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12753:SF0">
        <property type="entry name" value="ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05891">
        <property type="entry name" value="Methyltransf_PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016958">
        <property type="entry name" value="DUF858_MeTrfase_lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="147"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016958-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT62543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="258" mass="28919" checksum="9ED9494324854191" modified="2019-04-10" version="1">MEEETVTDHRNGKEESVNGEESMNEDESPLVNVDDLQKDPAFYSDAAAYWETIPATVNGMLGGLGHISTADISGSDAYLKSIFKMKNPPGHGRAVDCGAGIGRITKHLLQKHFGKVDLVEQCQNFIDKAKDNFKGSKKVTEFYCVGLQNFNPEPNTYDVIWCQWVLGHLTDTDLEDFFRRMAQGLKPNGVIVVKENVTSSGEVEFDKVDSSVTRPESEILDIVERAELKVLKNTKQPNFPKGLYEVKMFCFKPKHTHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUG2</accession>
    <name>A0A3R7LUG2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_017432</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003221">
        <property type="protein sequence ID" value="ROT64629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUG2"/>
    <dbReference type="STRING" id="6689.A0A3R7LUG2"/>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11367">
        <property type="entry name" value="RNase_PH_RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="32"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="198"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT64629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="290" mass="31998" checksum="D53DFD4C2F9BFEBD" modified="2019-04-10" version="1">MTDLNLSDAEKSYIVDGVKLGIRVDGRGRLDYRQLEIETGVVSTANGSARVRLDRTDVLVTVKMEIERPLPDQPENGRIHFFVNCSANATPEFEGRGGDDLATSLSAMMERVYSSPHTLDRSKLCVVKGKHVRGLYIDIEILECGGNLFDAISLGVKTALWATKMPKLYVTGEDGGELEFSVSDNPHDIDRIDVSNAPILITHLRITENLTVVDPTPEEECCGPVRVVVSVTPQGFITATQQFGSGTFNPQTLTASLKSARDLGQKIHNRLLRKLQQEEQMSDRQVKGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUG6</accession>
    <name>A0A3R7LUG6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Metalloendopeptidase</fullName>
            <ecNumber evidence="10">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_018816</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="10"/>
    <dbReference type="EMBL" id="QCYY01003452">
        <property type="protein sequence ID" value="ROT63307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUG6"/>
    <dbReference type="OrthoDB" id="10017459at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04280">
        <property type="entry name" value="ZnMc_astacin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034035">
        <property type="entry name" value="Astacin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001506">
        <property type="entry name" value="Peptidase_M12A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127">
        <property type="entry name" value="DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10127:SF780">
        <property type="entry name" value="METALLOENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01400">
        <property type="entry name" value="Astacin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00480">
        <property type="entry name" value="ASTACIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00042">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="Spermadhesin, CUB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51864">
        <property type="entry name" value="ASTACIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01180">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M12A" evidence="13">
        <location>
            <begin position="45"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="CUB" evidence="12">
        <location>
            <begin position="283"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="90"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT63307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="446" mass="49574" checksum="F9671B7309A8C4AD" modified="2019-04-10" version="1">MAFLFIRSQPRPFEETNPDRVEAGQLFDKDMLLTEAQWRDLALRKGLASQNYRWPESGDGFPHVPYRFADANVNQVAVKAGIAHWEQHTCLKFDLTTNENQPHLKFQKGSGCWSYVGYISQYSTGQDISIGQGCTSLGTVAHEIGHAIGFYHEQSRPDRDDSIHINEENIVYGRENNFAKISDSFVDSQGIPYDYSSDMHYSGFGFSKNGRLTIATVDPRNQELIGRRNGLSHRDTHLANLMYGCIDKWKQACSMDSDPCQNGGYTGANCACVCPQGTSGSSCETLEEDYFASQRSDCSARITSPGTVTSPNYPSNYPYGVVCAKWVVAPECKLPRVTFTAFRLSDCSDKLEIRTSNRYDGDFYCGTSIAPGTSFTSTTNELILMFYTRTNSETGWSADVTFIDDPNCSPATTQPPTTQPPTTQPPTTQPPHNLLHAVLYSLPAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LX65</accession>
    <name>A0A3R7LX65_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA recognition motif (RRM)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_016437</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003068">
        <property type="protein sequence ID" value="ROT65574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LX65"/>
    <dbReference type="STRING" id="6689.A0A3R7LX65"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12325">
        <property type="entry name" value="RRM1_hnRNPA_hnRNPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12329">
        <property type="entry name" value="RRM2_hnRNPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000477">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033">
        <property type="entry name" value="RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033:SF10">
        <property type="entry name" value="RNA-BINDING PROTEIN SQUID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="57"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="137"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT65574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="37724" checksum="93AB211BD86442C9" modified="2019-04-10" version="1">MADQEMEQQDFTEDYSGGDFQENGSGAAESQEGGGEGQTGEVQDSGAADAPGRDDDRKLFVGGLSWETTEKELREHFSKYGDIESINVKTDPNTGRSRGFAFIVFSVGEAVDKVIESGDHVINGKKVDPKKAKARHGKIFVGGLKPELSDDDIKNFFNQFGNIIEVEMPFDKQKSQRKGFCFITFDQESVVTDLLKTPKQTINGHDVDVKKATPKPDAMMRGGMRGGMRGRGGMRGRGRGWGQGWNQGGYGYNQGGYGSYGGYVVHRDSLFMALLALTRRARVQRGEEPAWEAAGEAPAVLNVIMATTRTPIGTAETCTSTDPRQVLNSSVLYCFWLPRRWYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LY32</accession>
    <name>A0A3R7LY32_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">GluClAc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_014273</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ligand-gated ion channel (TC 1.A.9) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002785">
        <property type="protein sequence ID" value="ROT67651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LY32"/>
    <dbReference type="OrthoDB" id="6339877at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006028">
        <property type="entry name" value="GABAA/Glycine_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00253">
        <property type="entry name" value="GABAARECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00252">
        <property type="entry name" value="NRIONCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="633"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="14">
        <location>
            <begin position="16"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT67651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="658" mass="73723" checksum="8F6A4B8690740D74" modified="2019-04-10" version="1">MKWKLEGEVQWTVQERESVCNTASRQVTIFPDRFSLKNAINLCQIVGGSLSVPLNEGENTWMYESSKSRSGYCSGGQGSGYLWLGANDVRTENEWVYWTSGQALAWEGPWRGAGPNGGNVENCLVMLTGNFPGLWSDIACLDSYAFCVPCEFDRLSVLYLKGAMLCEGSPINKQYIVSDEKNGRPLLSGFLHSDIFWDPAAGSWVLQSLKEEGVRATWTPSREGMYPFGTHQWTLGGEVCQMQPGTEIPLTLSVCGKGEYTCADGNCIDLSLRCNLRIDCPDESDESLCSVVDIPPGYNTNIPPPSPRKEKPLDVKLDVQLIAFPSIVTQDLSMTVTFKLSLQWTDVRLNYLNLKEDRSLNKLSSEEVADIWTPRVHFSNALGNVFTNLDAGSRLECLRESPSSPGPPYLPVEVNIFSGRENSLQMSQLYHVTYTCEFDLVMFPFDSQVCSLRFTMSSASAPFLRLAASRALYTGQKDLIEYTIRNVSVEEGTAGDFSSVTVYVSFSRRYEFYLLTLYIPTTLLILIAYSTFYFNPVIFQPRIIVAITALLVLSSLFTQTSNALPKTSYFKMVDVWLFFSILIIFIVVFIQTLVEFSSLETVFALKRRNKIIQTQGTKTASKPAPPLTLSLKILLIGRFLIPLIVVIFNISYWAKALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LZT4</accession>
    <name>A0A3R7LZT4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Regulator of nonsense transcripts 3A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_018695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003442">
        <property type="protein sequence ID" value="ROT63419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LZT4"/>
    <dbReference type="STRING" id="6689.A0A3R7LZT4"/>
    <dbReference type="OrthoDB" id="18087at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000717">
        <property type="entry name" value="regulator of nonsense transcripts 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF3" evidence="6">
        <location>
            <begin position="44"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT63419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="333" mass="37705" checksum="FCC76D26916D998E" modified="2019-04-10" version="1">MTVKANEGSKRDHPKSYNDHSSKRSVDNKQNAKTKKEKTTAPLTKVVVRRLPPAMTEEEFLEVVSPLPDHDYFMFSFTDSSLGAHAYNRAYINFKNVDDVYTFRDRFDGYVFVDQKGDEYPAMVEFAPFQKIPKRSGGKKKDARCGTIDEDPDFLAFMESLTNPTPVTLPNLEAVLEEIQAYDRELKYNADTEVKSQADEKDGKKVVVATKGQEEQVQSSEKCEEKKVAKMVDKQEDVERQVEKQPRKRREKDPRDRPAMALYRPGQSRLSSGHSRSEKEDGGDTCSSSPSPVMLQGDSNVFFGQGSKDVPEEPRIQEDLNVVKNEVNGESNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M0L6</accession>
    <name>A0A3R7M0L6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative neuropeptide Y receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_018027</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003333">
        <property type="protein sequence ID" value="ROT64056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M0L6"/>
    <dbReference type="OrthoDB" id="10053194at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004983">
        <property type="term" value="F:neuropeptide Y receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000611">
        <property type="entry name" value="NPY_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24238">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24238:SF73">
        <property type="entry name" value="RYAMIDE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01012">
        <property type="entry name" value="NRPEPTIDEYR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0807">Transducer</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="12">
        <location>
            <begin position="90"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT64056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="307" mass="34960" checksum="55BE6552D361E9F4" modified="2019-04-10" version="1">MATEEYRWDRFLSLPAEERNRSEEVLFLCDPDDNISVPVHKLMFACDLCLEKEEVLGLWRQGVCDLPPSPVFDTSIYVLYISILVFAVLGNSMVVYVVCSSAKMRTVTNYFIANLAVGDLFMAIFCVPFSFMSTLILKYWPFGGELCVAVNYLQAVSVFVSAYTLVAISLDRYFAIIYPLRPRMTRFQAKVIIAGVWVLALATTLPVAIYSKLFEPPLNWYRYFGHQVCTEDWGDSDSNKDSRTAYSVALMLLQYSLPLAVLIFTYSRIAVVVWGKKNLGETPARMDRIARSKRKVLFSHNGDHTTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M191</accession>
    <name>A0A3R7M191_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003247">
        <property type="protein sequence ID" value="ROT64493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M191"/>
    <dbReference type="OrthoDB" id="5973987at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051239">
        <property type="term" value="P:regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017855">
        <property type="entry name" value="SMAD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001132">
        <property type="entry name" value="SMAD_dom_Dwarfin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22742">
        <property type="entry name" value="EXPANSION, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22742:SF2">
        <property type="entry name" value="EXPANSION, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03166">
        <property type="entry name" value="MH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51076">
        <property type="entry name" value="MH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MH2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="259" mass="28580" checksum="4570E5307558821C" modified="2019-04-10" version="1" fragment="single">MLTPSPPPLSHPPSSHSLPYSQTPSPPPLSPSLLSTPSPPSPFSPPSSHPQGVKVKMDDHGNILIKRVSKANVYVKMASDDNAIGSDILRLPNLGLENEKPVMLFDMNKFIQNVKREMGRQYPDRSKLETQCVCLIAFVKNEQDILDCPIWVMIINIVAMDMLKSKLPPVRVMPNIRNRPRIPIPDEDPYSVAGGSGASSGSSGKDRAGKDKPPKLPPRDSNHPVPGSRPNGKSEALDENTFRKLQSRNNNNRSQDRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1C6</accession>
    <name>A0A3R7M1C6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_011551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfotransferase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002456">
        <property type="protein sequence ID" value="ROT70182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1C6"/>
    <dbReference type="STRING" id="6689.A0A3R7M1C6"/>
    <dbReference type="OrthoDB" id="205623at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11783">
        <property type="entry name" value="SULFOTRANSFERASE SULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransferase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT70182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="243" mass="27843" checksum="E8AECA3B9EC718A7" modified="2019-04-10" version="1">MLTHGCQESRPEDGTLETRFPFLEFPFPGVRAVAAMEGPRCIKTHLPRHLLPKSFASSGAKMIYVTRNPRDTAVSYYHFTQLLTVASFKGTLSDYVELFLRDKAMYSPFMPHVLGFWEARRDPNLLFVTYEELHQDALKAIRRIAHFLQASPFSVEASEEQLEYVAACTSFASMASNPSVNYEHWKDSGFCHKDKGSFLRKGKVGGWKESLSAEQIEAFQRWEDRHLAHSDFRFTFTSGEARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1V5</accession>
    <name>A0A3R7M1V5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_012271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002557">
        <property type="protein sequence ID" value="ROT69504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1V5"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT69504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="14121" checksum="BC21403C2B979A80" modified="2019-04-10" version="1">MASPEVLSRMEQRAIQAEQMIDLLTKQISQLQIAVVDAQKDQLRRENQHLRQEVDSLKRRLVDLEKSQGIKQYYDFTNKTTPSSEAIAEVQPAANTSAPPPTVADKPQQEKPQKVSILVFCAMNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3W3</accession>
    <name>A0A3R7M3W3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002330">
        <property type="protein sequence ID" value="ROT71215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3W3"/>
    <dbReference type="STRING" id="6689.A0A3R7M3W3"/>
    <dbReference type="OrthoDB" id="10041151at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="797"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="981"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="515"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="599"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="802"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1014" mass="107777" checksum="5C9961387E0BACCF" modified="2019-04-10" version="1">MPNKKTRPPKEEQGRASRVRTRPKGMSGEIQPSWKPEFRRTEMPPYIINIVDVPFNDDYVCISGGSECGVASPPTLYTAPLEPMVVDPLQQPDAAPAAAPQDSEAAAAPVASPQPEAPAMVGSAGLDTVRARCCPLVPSSDLAGDDAMIHQSDKSPTITVTATSTTSTTDMTDGEMENLNQVNGNTVVSPASTEDSGVNLTSSYTEDPAATDVSASVRDSPSKSSCTNIERPSPNCAIYDFKHQDTDTEEAAANTATSTDTAACQANLNLVECDPARNRIYQVRRRGVRSVVRTSARTRLEFSCDEEVDHEALQKIIDSAILDPDWLNSNMPSDSEASATEDEAPLQEHMDTGSDGGTPGHPHPQQEDQVAAQNQPLHQEAQRTISKESITRLVSDAERLVREPPEGDQPAPLVSPRPHQLPLNMGPCKGAMGSKQASARREARLSTTCVMDSCDASGELTTGESDIESCTSEDMDASTATQHAVSTRGSVRGSQKGSLKGSRDPLPSTDNTPTAEKAAAVPSPADAAHPKVVLRSRKRRSGEQRPCSVSELYQLATRLDLAPFSVSETALHNLLTATPETPTNDNQAFGAETPDAAGSNTSPTDVSTPTTTGPPATPATNTTNTTITSTTHPNISASATITTSTTSTTADRQSPATNATGSLRRRKTRARRKSNLSLGRRTDSGSDGLALNLSGGSDNNQVSPNRRLSKSHSSGSDTASHCRRHIVKSSSFSGACRGGSGGMTSSTEKCVSDCGGVLGVPRLHTRALAVDDCCSSDESRPSSPAPALLEAIVPRSPAHTARSATQSDQDALNTHEDMSSLSEQAWDPYQQEYKYFSEPYSEDIDQEAARRLLEFGDDYRKYIDSDGASSFSGIPHRGRRSPTTVENVLKKYSNEAALGLDYAELVATTQTNIKCLAEIVRHLQMEGTLEPELQELTLKPLSSALAGVLCQGSPAVATVTAGQSNHPGLWRGRPKLITAPPAATALSDLVSPSQQEDPRPEHTRDEHGAGERAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5A0</accession>
    <name>A0A3R7M5A0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Down syndrome cell adhesion molecule-like protein Dscam2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_008293</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002044">
        <property type="protein sequence ID" value="ROT73273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="152385at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030424">
        <property type="term" value="C:axon"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098632">
        <property type="term" value="F:cell-cell adhesion mediator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007411">
        <property type="term" value="P:axon guidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070593">
        <property type="term" value="P:dendrite self-avoidance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000333">
        <property type="entry name" value="Down syndrome cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000028">
        <property type="entry name" value="Neuronal cell adhesion molecule"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075">
        <property type="entry name" value="BASIGIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10075:SF100">
        <property type="entry name" value="FASCICLIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="64"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="224"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="315"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="412"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="554"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="654"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="5">
        <location>
            <begin position="837"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="4">
        <location>
            <begin position="935"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="164"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="482"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="636"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="751"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="491"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="517"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="656"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1198"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1236"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1248"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1260"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1338"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1375"/>
            <end position="1418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT73273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1418" mass="151122" checksum="F2CF7D5901344BB6" modified="2019-04-10" version="1">MSVHMGGMGGMGGMRDRQSFAPSPGSAVLVIEAARASDAHAYTCTANNTLGVDQMSVEVLVESPLQVTVIPRSLTADLGGTATFSCSVSDPAATVSWYYNGSPVVGSGRVVAAGRQLIVSGVNRDDPGMYQCQAIRGTRAAQQAAQLMLGDSAPVLHYRFIEQTIQPGPPGRRRGAAGDALGGRQPRQRLPHASRRRRPVRVRRHEPRRIHGAHAANLNIYGFPVSRPLASVTAVSEEKLHLRCPVAGYPLHSFAWTKDGKSVDSDPGRIVQADGTLVVEQVKRPADAGVYTCTASTKPGRSATGSVQVSVRVPPRIQPFKFQEGLSEGMRTRVVCGVNQGDAPLKLEWLKDGRPLSLGGPPNVQVKVIDAFSSVMVISSLTSAHSGRYTCEAHNAAAAVRFTASLSVHVPPSWVLEPADTRVSRGHALVVDCVARGHPEPSVTWKKKVTREGQSTGSDAFRSVELVSPRAVQLSNGSLYIAAPNPSTPGPTCARPRTPSRTCPPRSPSPSIKYVCVRREARQEPRRRSADAGAEGGVAPPLRQIRGDGEGDFWRRNGGEADVSEGSRAVRVSWAAPDPPPTSYVVQFRRALEGWGEAREVSVSGESVSAGVEVSPLLPATDYVVRLVAVNHLGRSPPSEDLRLTTSAEKPGAPPRDLRAEATGPREVRVSWRPPPRDRAYGVILGYYLGYTPVLLQSGASGSPQYNFTTVESSEGGRSGPEGEGTWSVTVSSLDPHTDYHVVVQAYNTEGAGPLSPPATVTTREDAPGGAPQEVRCTGLSWDSVQISWSPPEPHLHHGTLRGYKIEYERWDGWSEAIKKSQTNGADAVLTDGWRRPPTTVCGVRGVVSGPGAFIVSWAPPIRPGGRIVSYTVTWRVVGARMGGGHGREGVITVAGSVTWNNVLGSLVEVEVVASTRVGEGPPGATRVTITNTVPAAIYSHSASIRAERGRDVTLPCGHVGQPRPHLVWKYQGRPVGSEARMVKGDGGLVRAGGAELDSGNYTCTVTNEHGTDHITYSLTVLVAHRAPRAGLLPVRAQRPGPVEARGQRGCAITGYTLYYRKDHGAWTQVHVNRHSSSYTLTSNLSFHPISSRDPSINYPPVHTHPHLLSLSRRNPLSIQSIHYHTVHSAYHFSSLPFTSIVCPEDARRADGGRARREGTTTAGGRRGAGAEGAGRAEARGRPGRRRRGKEQQNQGRSRPERGDARRRAATDERPAGSGGTEAEGEEQGEQPATKDGQKEPAEERRRSEKRRAGGKGPKRPQERGAKSDEPEGDKKEPGRARGSEEAGPSGRGPRGANTAKGAQPRGTPGTRRRRKGRAGAARAQRREGEGATSGRQRAGGRGGGGRGKAGEGQAARDPDAEPARSTSGTAGSRLARDRGERRGPERGTKGARGRAEGTSRKEGDSAKTEKGPRGETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5F4</accession>
    <name>A0A3R7M5F4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative alpha-ketoglutarate-dependent dioxygenase alkB-like 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002142">
        <property type="protein sequence ID" value="ROT72493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M5F4"/>
    <dbReference type="STRING" id="6689.A0A3R7M5F4"/>
    <dbReference type="OrthoDB" id="442860at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032451">
        <property type="term" value="F:demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070988">
        <property type="term" value="P:demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF0">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="186" mass="21552" checksum="B552F5B465F5AEC3" modified="2019-04-10" version="1">MFHNRPCGCKGQRTCLTCEESYEDVASKAKSWVTDEEKEKSYVYCPECDLAWPGWEADSWKVHPDHAGDSIKFPGIKVIQNFITEDEEEELMKHLDEVPWDLSQSGRRKQNYGPKCNFKKRRAKAENFSGYPAFTKFIQDRFASVDVLKNFQTVEQCSLDYPVETGASIDPHIDDCWIWGERIPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAH8</accession>
    <name>A0A3R7MAH8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Kelch-like protein diablo</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_004862</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May have a role in synapse differentiation and growth.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001645">
        <property type="protein sequence ID" value="ROT76558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAH8"/>
    <dbReference type="STRING" id="6689.A0A3R7MAH8"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18459">
        <property type="entry name" value="BACK_KLHL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.420:FF:000001">
        <property type="entry name" value="Kelch-like family member 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000001">
        <property type="entry name" value="Kelch-like family member 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011705">
        <property type="entry name" value="BACK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017096">
        <property type="entry name" value="BTB-kelch_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412">
        <property type="entry name" value="KELCH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24412:SF451">
        <property type="entry name" value="KELCH-LIKE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07707">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037037">
        <property type="entry name" value="Kelch-like_protein_gigaxonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00875">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="BTB" evidence="8">
        <location>
            <begin position="98"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT76558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="639" mass="71149" checksum="F70E5183201C1D7D" modified="2019-04-10" version="1">MTSKICFNRILRAPLCDEQSQCGRLSYYSMEGPTETMMNLRVGQTVVRVAGGDEGVAVAGETSLRGPPSPTGLPYASDKHPKLALANINMLQKRRELCDVVLIVGARKIFAHRVILSACSPYFHAMFTSELLEARQTEVPIRDIDEHAVDLLVNFCYTSEITIEESNVQTLLPAACLLQMQEIQEVCCEFLKQQLHPSNCLGIRAFADTHSCRDLLRIADKFTQHNFQEVMESEEFMELPVNQLMDIISSDELNVRSEEQVFSAVMAWVKYNVTERRPYLAQVLEHVRLPLLSPKFLVGTVGSDLLIKSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPIKTGEVLFAVGGWCSGDAIASVERFEPTTREWRMVAPMSKRRCGVGVAVLSDLLYAVGGHDGQSYLNSVERYDPQTNQWLCEVAPTSTCRTSVGVAVLDGYLYAVGGQDGVSCLNVVERYDPQSNRWTKVASMNTRRLGVAVAVLGGFLYAVGGSDGQSPLNTVERYDPKLNKWVMMPAMSTRRKHLGCAVYNNMIYAVGGRDDCTELSSAERYNPHTNQWSPIVAMTSRRSGVGLAVVNGMLYAVGGFDGTTYLKTIEMYDPDQNQWQLCGSMNYRRLGGGVGVVKLPHNEAHLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MAM3</accession>
    <name>A0A3R7MAM3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_003819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001512">
        <property type="protein sequence ID" value="ROT77536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MAM3"/>
    <dbReference type="OrthoDB" id="6379363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="284" mass="31585" checksum="F4CC4BC650A44A1B" modified="2019-04-10" version="1">MEGQLQFLITPFPLQWQSLQCGPEECLLQLPSGEAADEGRPEAFLARAQVGPAPASTCPGRGGWQWQVRAEGDTTFLWLAWQDDLVLRRTPRKEPPQILRRCGRSCPQTPSPPLVLWGEQDPLPHLLGQYLLPDLHLSFDAFFRRFRIDRLLLPDLVDCPPECQSLAASIFNLLDASADGLLNQLDATYLTRAGVRSLTLQLDELLDELRDMGTEQWVHVVQGPHPGQPIVLGSFLYPLGRAAKGPSSIMVVIWRQAQVSAVWNLTGTQKARNDEACCGHPSCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MFX6</accession>
    <name>A0A3R7MFX6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Iroquois-class homeodomain protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025306</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000958">
        <property type="protein sequence ID" value="ROT81541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MFX6"/>
    <dbReference type="STRING" id="6689.A0A3R7MFX6"/>
    <dbReference type="OrthoDB" id="5399138at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003893">
        <property type="entry name" value="Iroquois_homeo"/>
    </dbReference>
    <dbReference type="SMART" id="SM00548">
        <property type="entry name" value="IRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iroquois-class homeodomain protein" evidence="2">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="256" mass="25778" checksum="124ABAA2F99B9B63" modified="2019-04-10" version="1">MWPAVTAAISPTPTLHPTNHFTVPKGEKSDCAVSLPSAKPKIWSLADTAACKTPPPTGGPPGSGWLAGGTTFPLPPTIPPAQQQYTRFNHLMTGVNPAQYMAGYSDGVGTDTPPQTPPNAKGQQNQQGQGGLGAGAFLGGSTSGSYGANMAGGLSSCSRGSTAPLPAPGAAGAPVGDASLHQRYQGPTSHAGSVTHTNTGAATMPSTAFTPVYKTSQQGGPQVAQQTSQMANQQQMPCQQSQQVQGGPVTAGPYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGE7</accession>
    <name>A0A3R7MGE7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Myosin heavy chain type 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024899</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000903">
        <property type="protein sequence ID" value="ROT81954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGE7"/>
    <dbReference type="STRING" id="6689.A0A3R7MGE7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032982">
        <property type="term" value="C:myosin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006936">
        <property type="term" value="P:muscle contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045214">
        <property type="term" value="P:sarcomere organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000008">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.370:FF:000009">
        <property type="entry name" value="Myosin heavy chain, isoform G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002928">
        <property type="entry name" value="Myosin_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF27">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01576">
        <property type="entry name" value="Myosin_tail_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90257">
        <property type="entry name" value="Myosin rod fragments"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin tail" evidence="5">
        <location>
            <begin position="12"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="87"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT81954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="299" mass="34549" checksum="B16562A0FA87168D" modified="2019-04-10" version="1">MQIESLNVKNLHLEKTKLRAAAELDDLQVAAERAQTLANSADKKQKNFDKIISEWKLKVDDLGAEFDASQKECRNYATEHFRLKAAYEENIEQLDSIRRENKNLNDEIRDLMDQIGEGGRTYHEAQKNAKRLELEKEELQAALEEAEAALEQEENKVLRTQLELSQVRQEIDRRVQEKEEEFDNTRKCHQRALDSMQASLEVEAKGKAEALRLKKKLESDINELEIALDHANKANSDLQKHYKKIYDETKGMEGRVKDEQRLASEYREQYGIAEANAPLWRTPGIPHSPGTVRSRPSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHU0</accession>
    <name>A0A3R7MHU0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001594">
        <property type="protein sequence ID" value="ROT76912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHU0"/>
    <dbReference type="STRING" id="6689.A0A3R7MHU0"/>
    <dbReference type="OrthoDB" id="10017443at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018795">
        <property type="entry name" value="K2013-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31386:SF2">
        <property type="entry name" value="SIMILAR TO RIKEN CDNA 2510039O18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31386">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN KIAA2013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10222">
        <property type="entry name" value="DUF2152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="608"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="733"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="760" mass="85539" checksum="E9557A818EE68EDD" modified="2019-04-10" version="1">MRTYHMTRCQVSNQNRREDVDWVLNISSLVMDVNEVIKRAKRAFDGYISYRKAVLVVLVILVILLYSGPSLFRLVTNRRPVLAGEDSASRSLSLRLDRFWQAVQDHDAHILHVPPLPEEEPFLPYVGNGLLGVSLDQESPIYIRSGRTLSLPVNYRPITLVSVDGMSVKEAIVTEYTTGTVHRLQSWDQPGIGPLDVTYKLYAHRTMPSLLLQDIKITNPTDQDAIVDVEQMGLGDWPSAATESIKLQHGEGEHEYVVISGSVDVPDSKSVVPVALITLKVPSSLQIKSKMSATLHVVTALNYSDPIPRKAYVSSVKNRASEAALAVLKRAVTGNIKRLRTDHSLVWKDLWSSGFFISHSKAESALNGNLINATLYHVLSQARAPLHEVTTTDEQRASILTDIAYAEGCYGGHQTLEAERLWSSLDTITNVNKVVGYWMVTLEKQGCHQLVRAGANGVMQAMLLSFGGLRFKNQHLEFTAQPKDLHRDYHFRRISYGNATHLNLTVVVQEEDYKAVVYVAVDRSDRSYYACDAGCLDQLVELRQEKQMFPVKLTEPVTPILYITSDRAHLEELKHTIHVKEIALAPPHEHHVIAMHKHGHKWGGLPTVFWLTIVALIVIFHLFLIKLVINEYCGGDVKVRYSPENSHYDWNHSGLRFPHASGLDLKVLVPMELFHFPERERWTVLVTAVVIVILSFPPPSISVFLSLFYSLFFPLSLVFLLPPNPLFPFLSSFFPPLFSSFPPFLSAYPPFLPFFSSSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ90</accession>
    <name>A0A3R7MJ90_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_018918</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003476">
        <property type="protein sequence ID" value="ROT63164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ90"/>
    <dbReference type="STRING" id="6689.A0A3R7MJ90"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000474">
        <property type="entry name" value="zinc finger protein 367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF26">
        <property type="entry name" value="ZINC FINGER PROTEIN 367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="329"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="391"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT63164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="451" mass="50954" checksum="7AC666DA1A269487" modified="2019-04-10" version="1">MSEKCREDSQFSTPKRRQNGAFSGMSFSGSPPMTDNTLYPWNWGENACKVELSSPCCSGGSNPCESPDLKSCDSKRGRPRADAINTLIIEGAQSPSSIKCPICNRVFPREKSLQAHLRTHTDSGNVFKRTKRSHFGPNHRDLPPTRSPSDDPHLPSRRENAMERRKEKRRVFKRDCLSWRIAQRLAGTPQDLVAGKALFPLVLGRCVALWQLNRRPLQRLPGNLSFVAVIHNDAGAGERPYQCDYPGCTKAFTQSGQLKTHQRLHTGEKPFICSAPGCTSRFTHANRHCAEHPYATLNRTPDLNFNPQLPSAECTDDILRWLEKYRSERMERTPAKSRKNKREFEGTPETPQTPCTPSSDSDIMSPPPVKRTKSRRGLGPLMEQQQNHLDHRPGTIFQGHNRTDENAYIPSGDSYGVTRTSTVITRDHRDQCQHRQPMPGFSETQKIYKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7ML26</accession>
    <name>A0A3R7ML26_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proton-coupled folate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_009381</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000219">
        <property type="protein sequence ID" value="ROT85669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7ML26"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="452"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="235"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="235"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT85669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="59243" checksum="A45A0B62F3770B70" modified="2019-04-10" version="1">MASESKTNTTLGKVRGFLGEISIEPILFLYYIGLYSRSVVRENLKLDRFCRITLGYDEEDCALLNDGHHGDIQAETQKLDSVFYFYEKVVSTVVPLVLISFTATWSDRRGRKALIVLSFVGDLLYIFIYLLESLFPSWPPQVLLLASFLNSLGGGMMMLLMACYSFMADKTNAKTRTVRMTIMNSIMHMGGPIGTVLGAWVFAAKGYVWVFGLGLVIIVACLLLVIFVIRDKDSSSDNKEASSDVDVRKEAPGHANDTKEAPGHANDTKEAPGHANDTKEAPGHANDTKEAPGDSSEGKTPGSPWDPRNIVDLFRVCFRRRPGRGRSHLIVLMLIMLSQISTMPHNLYLWTRRVYLWDENQYSLYSTVNQVLEQAMSLLAAPVLHKLAVHDCSMGAGVAFIIFLKLLTLGLTTSPSQWWVIYLFAIMPSGITSAAIRALMSKICDADEVGRIFSMLAILEVLWPLVDSAIFTAVYSSTLDFYPSYEHLVGAFFGFVLLTGFLGLRYSLEQVKNRAGRRAAEEGLAEEEGAVKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MQG0</accession>
    <name>A0A3R7MQG0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002816">
        <property type="protein sequence ID" value="ROT67385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MQG0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="492" mass="54522" checksum="FD20D209E2F7534F" modified="2019-04-10" version="1">MPPRCPQAYPFDVPPRHTPSTCPQGIPLRRAPKAYPLDVTIPEKCPCPGVPQDVPPGLFPRSVPTFPKTSPQTIPESVPRTFPKTCPQDYSREVSLGRFPRRAPRTIPEKCPRSPTKVPPGRPREVEEVPPGRSPRGPQEFPAPRTFPETRTFPPPDDDPKGAPSVPRDVPPDVPRDAQDVPEVPPGRSPRGAPRTPEGPRRSRKVPPGRSPRGAPRTFPERCPQDVPREVPPGRSPRSAPRTIPETCPQDVPRDVPPGPQFPETCPQDVPRTCPQDVPEKCLQDYSRDVPQDVPETCPQRTPRRSPRRAPRTFPAPPGLPRDVPQETSQDVPPGHYPRRAQDVPPGLFPDVPQDVPPERRAPRTFPETVPERCPQDVPREVSPRHFRDVPLGLFPRRREGPTHLITSRALRSGSPPGAAPRFALRPLITSRLSPAAEEKVAMAGSHGLSPLVRIGVWRVCGGFELLSPYLRVARIRREGGDRQPLTPFPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NB38</accession>
    <name>A0A3R7NB38_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Meiotic recombination protein DMC1/LIM15 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_024516</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Double stacked ring-shaped homooctamer. Interacts with BRCA2. Interacts with the MND1-PSMC3IP heterodimer. Interacts with RAD51AP1; the interaction is direct and stimulates DMC1-mediated homologous recombination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecA family. DMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000847">
        <property type="protein sequence ID" value="ROT82312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NB38"/>
    <dbReference type="STRING" id="6689.A0A3R7NB38"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19514">
        <property type="entry name" value="DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000239">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000032">
        <property type="entry name" value="meiotic recombination protein DMC1/LIM15 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011940">
        <property type="entry name" value="Dmc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02238">
        <property type="entry name" value="recomb_DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="13">
        <location>
            <begin position="97"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="14">
        <location>
            <begin position="278"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00064395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT82312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="341" mass="37546" checksum="EC694BB59340E607" modified="2019-04-10" version="1">MEDQALDAEECILDDEVSFFTDIDELQAHGINAADIKKLKSAGICTVRGIQMTTRRRLCMIKGISEAKVDKIKEVAAKLCGGDGFVTALVMCEKRRLVFRVSTGSAELDALLGGGIESMAITEVFGEFRTGKTQISHTLCVTAQIPNEAGTYSGGKVIFIDTENTFRPDRLRPIADRYNLEQDAVLDNVLYTRAFTSEHQLEILDHVAAQFHEEPGIFKLLIVDSVMALFRVDFSGRGELADRQQKLAQYMSRLQKISEEYNVSVFITNQMTADPGAAMSFQADPKKPIGGHILAHASTTRVCLRKGRGETRIAKIYDSPELPENECTFAITAGGIADAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NC57</accession>
    <name>A0A3R7NC57_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative collagen alpha-2(IV) chain-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000715">
        <property type="protein sequence ID" value="ROT83226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="8058206at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005581">
        <property type="term" value="C:collagen trimer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0176">Collagen</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="1222"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1297" mass="138290" checksum="E032C56659E81186" modified="2019-04-10" version="1">MEGSFALPSSPSQPVIEGSFDLPSSPSQPAIEGSFNLHSSPSQPQIEGSFDLPSSPSQPAIEGSFNLHSSPSQPPIEAPIEGSFNLHSSPSQPAIEGSFDLLLPITATIEGSFDLHSSSQPRRPPKKGHLTSFFPITASHHSQKGPFLPHHSLLTFLLPQPNEGSFDLPSSPSSPIEGSFDLPSSPSQPPIEGSFDSPSPSQPPIEGSFDPFFPITRRPAIEGSFDFLLPHHSSNRRPPIEGSFDLPSSHPASNRRQIEGSFDLPSSPSQPAIIEGSFDLPSSPSQPAIEGSFDLLLPSQPAIEGSLPSFFPITIEGSFDLPSSPSQPQEGSFDFLLPITASNRRPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGHFDLPSSPSQPIERSFDLPSSITASNRRPAIEGSFDLPSSPSKPAIEGSFDLPSSHHSQQIEGSFDLPSSPSATIEGLPFCNTQPDQQPPIEGSFGLPSSPSQPAIEGSFDLPSSLSQPAIEGSFQSFDLPSSPSQPPIEGSSDLPSSPSQPPTEGSFDLPSSPSQPAIEGSFDLPSSPSQPPIRPPIEGSFDLPHHSHQEKGHLTFLLPHHSQPIEGTKRRSFDLPSSPSQPAIERSFDLPSSPSQPAIEGSFDLPSSPSQPTSNRRGHLTFLLPQPAIERSLTFLSSPSQPAIEGSFDLPSSPSQPAIEAAIEGSFDLPSSPSQPPKKPAKEGSFDLPSSPSQPAIEGSFDLPSSSAQPAIEGSFDLPHHSHQKKGRSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPAIEGSFDLPSSPSQPPIEGHLRRRGPKINGNDRLPSTTVQQEAPVTASLNLNTTYDANFAAAIAELFGFTIEPMSYRPKPVVKEPSGQTLPKQANAGVSLPMPHAGNLVVPFLVKGKQEAAQAFIQHMEACICGNRPLRMPLQIPVFLQPLLKTKQAPGIRLKMPLREDDPSVSCALIVKEKDCALMLKKLADIGGQVRSAESASPDIAPAHYGKAIGKGGARISYIREKYGVQFNVPKDRESPIVVSGLSANVRGAIKELEELVQQDVLQQRVVLPVEILPKDIGIAIEKGGCHASKVQDEFRVKLRTHSREHPEWPLVVEGPLGAAEKAVASIQLQELKGTIPVCHEPGAQILVTGLKENARAAVAELELMANLKLRPEHVLVPLHIRREEHILVLGPGGSMAAWIERNYGVQFLWPRAENMPLLLVRLAEDVSRAEAAIMKRLSGRRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NEB6</accession>
    <name>A0A3R7NEB6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000468">
        <property type="protein sequence ID" value="ROT84935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NEB6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="568" mass="61665" checksum="0B70E3AA87EB230A" modified="2019-04-10" version="1">MNSLFGMSVLQSLYCDRKLRPFKSRPPSPALSPSQYPLTTFFLLHPLPCSNYPLSNLFLCPPPPFSSTPYDPLHLPFLLLFLPPLIIHPTPTRPRIPPSPPPTHTNSTGHDPCTTCSHAASNNPLYQLCQAGILISQSQAVEETKTRTRKQVHKEAGRGEILSAAGDESAGEEVPKSLPHSLPHTVTCRCDVTHASPSPPSLCRFITPSRDNNTISRQQGGAITPLSLTMALHRPRPSSHHAVNSNIPENKEKPYECQCPARQLRGVKNCEENHDLLRKGRSIPTHRGGQGAEGGLGGGGTYLPAPPPHPTNTVTKGLRSPPPPSTSFIFYYCLTNFTHIHLHHLIHLYILPPSPPLQPTSPPLPTTCTSTNLLHIYHFHHSLLHLHLHPLPLPTTSPSPPPTSPPPPPTSPSPPPTLFTPPNLSFTPPTSHLPTFQPPPPQPHLHQPSITLANHPTESKRKSIASVSLLAPNDALGAHFITISEATPSRAHHNCQGLFITVLTISGRGGHHTSRISLDVGPPGGGADLTHLPYKVKGQVATERVGTRQVDTGHMGTKQVRKRQMGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NRJ4</accession>
    <name>A0A3R7NRJ4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulator of G-protein signaling 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017261</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003188">
        <property type="protein sequence ID" value="ROT64809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NRJ4"/>
    <dbReference type="STRING" id="6689.A0A3R7NRJ4"/>
    <dbReference type="OrthoDB" id="196547at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008277">
        <property type="term" value="P:regulation of G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06710">
        <property type="entry name" value="PDZ_RGS12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13162">
        <property type="entry name" value="PTB_RGS12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046995">
        <property type="entry name" value="RGS10/12/14-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45945">
        <property type="entry name" value="REGULATOR OF G-PROTEIN SIGNALING LOCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45945:SF3">
        <property type="entry name" value="REGULATOR OF G-PROTEIN SIGNALING LOCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00640">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01179">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="17"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="PID" evidence="3">
        <location>
            <begin position="253"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="868"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="925"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1044"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="494"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="935"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="956"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1098" mass="119460" checksum="2BD4DB27E308C8F6" modified="2019-04-10" version="1">MHNNRRRKKRPSYGVRTVEITKGKNGFGFTISGQAPCILSCIVPGSPAERAGLRPGDYLIAVNSQNVSKAPHDDVARLIGLSKLLKLQIAENYYSDSSDDEFVTVNRPKPKYPNRLRHKNQQTRAEKVVRDLQSGAIFSEHTAIHLGEAALLSDRDAWPESAFPPKAPLTPTPKGLTVSTSVSPVPEGLGGGDGGPAGVPSSTSPTRLRPDQIQLVMAEARQEINKLLYPTLAELQQQAAPNDLGEALYRAVVGYLGTIEMPKEPQGGSRLAAIRNCIRRLRIEKKVHTLVLMSVFTERVVLTSPHGLTLAQYPAERITFCGVYADDKKFFGLVTVHGASGDELSDGSQDGGSVSSSCHVFMVDPRMVQHADHARRAKNFRLECTPHPDAPHCQEFPDSADPILHSIMSLYRNRVGFHLDTGAPGLIDVEAQMSPQHSNTSSNSSNSDSGIGFRDDGGHHYHHNDRVFVVEVDDNQRMRIQNFQLVSNLRANLNDNLRSNIDNHRGNIDNHRGNMENQRGNMDNHRGNMDNHRGNMDNHRGNMDNLRGNMDNHRGNIDIHRGNIDSHRGNLDNHRGNMDSHRGLDNHRSNMDNLRVNLDSHRANLDNLRPSSTDNFRSNLETHRVHLDNLRGSITAGYGGGVVSASVTDSIANSLSANVLRANINDFNPSSANNLRAIASEKLLVSASESSSAKLLDNVRANVNDHLRVSVTDKVLGNVDNLRVSVSDAKRLSDLRASLAESRASLVDGRTSITDDLRAALEDEVRAGLHDGRTSGVDGRTSITDDTRLARDRGATKTPVADCSATPETGRLTVRAMPDPVGFERSPGSLSSSDTPVHVASMRHSMHKYLQHKQEHLVKVSQKINRRESDTGGIHPLSVRAFSPATTKPSPPTPTVTASAQETLDLELSIKLSPKVFGVPQLPLGGALSPLRPRAPSERSYTRSLEDLRDSSTSDGVGGPLASGGCGSSFRDGSESDHGLDRLRHVPLTPLARLLHASENNLTRYGNIYPSEHHRGAFRAVAPRTHREPPAPLGVGVVPRMGGLVGVGALDSGDEHTENTENTGEQEGSQDVHPPTQDEFSHDSDSEQVSVGLLGLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NUN4</accession>
    <name>A0A3R7NUN4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014762</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002838">
        <property type="protein sequence ID" value="ROT67171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NUN4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="468" mass="50019" checksum="55FAACFA3515D60C" modified="2019-04-10" version="1">MIPRRFPRSWRTEAVDSRHASRDARLQGRGSRLLQSPPALTPSPLLLPSPSSSFSFYLPFPSSILLPSTSRFSHLPPSFPPSFSPPSFPTSLLLPSTSFFPPPSPSSSSFSFYLLPSLPLFPPSYSFPPPSPSLPSLSLLPPLSLLPFAILFGLLLSPKVSARSLGLLVSVDQVDLHTLPSPSPPLPSHPRMSHLPRGMEVAECGMVVEPRLSAYSSALRTQEGDAHVYAHTLITKYDHNERLLDERASEEPLGGSHVFILRLRGPSVRFLAWYVLSADGLPRGRPSFDSASCEAFSLAVERLPNCSRSLGFSREGRAPPPSPSGKGSGGTGGANNNPLIARERVVFSRVRVPSKAAVACFHGGGAGDACRSAQLVASFPPRGGDESPPYARIPPTSASLRHPEAQSFRALSGSDEESAYRARAAIIHTVHAQAGRRTRTVLLRARVAQPIPAGQPLIIAAPGTASGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PAX3</accession>
    <name>A0A3R7PAX3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative class A rhodopsin-like G-protein coupled receptor GPRgrp</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_000790</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001116">
        <property type="protein sequence ID" value="ROT80482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PAX3"/>
    <dbReference type="OrthoDB" id="10049706at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008188">
        <property type="term" value="F:neuropeptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695">
        <property type="entry name" value="LEUCOKININ RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45695:SF26">
        <property type="entry name" value="NEUROPEPTIDE CCHAMIDE-1 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="11">
        <location>
            <begin position="23"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT80482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="174" mass="19031" checksum="43639CD65CAE3AB2" modified="2019-04-10" version="1">MKGNLTQSVSPASSHPRKKDFNCNGCLIVIFVKNKTLRNVPNTYIISLALGDLLVLFFSVPFVSTIYTIESWPYGTFECKFSELVRDVSVGVTVFTLTALSADRYLAIVSTVRRAAGGAGRRTVRFAVAIWFLAVVLATPAGVFSHVQVFQVSEGKTISVCYPFPDYLPVVPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBJ9</accession>
    <name>A0A3R7PBJ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative adhesive plaque matrix protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001043">
        <property type="protein sequence ID" value="ROT80964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7PBJ9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="58594" checksum="56BDE29602D6E474" modified="2019-04-10" version="1">MLSLQSPPVSPVTVDWCRRSECHTDTWSLAFSLTFSFSFLSLSLSHIPASSSILPLPYHLLPPPPPLLPPPPPLLPPSSPSFLRPSLSLSSPNPPSFPPSLPPTLLPLYLRSPYFQQQLHREGKPGKLDGELQVARSHRTSRRTALPSPRASTAADSLFRYVNGIPVEQEELVIQAGVLSHYPVHVWHEHQGLGQLDHLCYLVGTQLRLSQVVPIWFRLSQVVPIWFRLYQVVFICLRLAQVVPIWLRLAQVVPIWLRLAQVVPIWLRLAQVVPIWLRLAQVVPIWIRLAKVVPIWLRLAQVVPIWLRLAQVVPIWLRLAQVVPIWIRLAQVVPIWIRLAQVVPIWFRLAQVVPIWIRLAQVVPIWLRLVQVVPIWIRLAQVVPIWFRLAQVVPIWLRLAQVVPIWIRLAQVVPIWLRLAQVVPIWLRLAQVIPIWLRLAQVVPIWLRLSQVVPIWLRLVQVVPIWIRLSQVVPIWLRLAQVVPIWLRLVQVVPIWIRLVKWFLSGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PHK9</accession>
    <name>A0A3R7PHK9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_015197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002892">
        <property type="protein sequence ID" value="ROT66745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PHK9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT66745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="471" mass="52411" checksum="54A1C0EB5EBB7B78" modified="2019-04-10" version="1">MSLFMSNGHGIEPTTVEGRYAYITTDSSGSSIWRLPLATTNNDLDIATGTLVYGGLGAGTALTLLTMAHAVFFGKRRKRDLRSVLEDNLDDPTIAADFERIYASDTNWCGLRLTCELAAKAGAPLTEEEKMMLSFFRGMVSAEDLQEMDTPQLYYSYASFVGFSQGDPEKCQQMYSKCPYSAKKMMQVYRTAHFRSAEKRRDQLQPKTAARARRVPLTRPKAILQYTIKPAPATFPPYSGGRARSRPVGCIRAYGRDFISLKDSVWPTLILMSQSSLWTLCHVQASDASFQGHHSHVAMQHGVQVCGAMMYFYAMFKLGIVGAIFLIVGIINVGMTSTASTRQSYQAQNALATVGKVFIGLGVIILFICLLLGCIGRRRYKDVEERLRREVNAIRLTQQPSNALFPHPDMYPGQAVFHTRSSMHGSYPQNYPDQPTPRSDYTLARAGPREGEAYITEERMRALDKDSRGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PJ03</accession>
    <name>A0A3R7PJ03_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002029">
        <property type="protein sequence ID" value="ROT73402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PJ03"/>
    <dbReference type="STRING" id="6689.A0A3R7PJ03"/>
    <dbReference type="OrthoDB" id="6379255at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826:SF3">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="96"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="483"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="762"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="692"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="768"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="795" mass="89214" checksum="09DF9F3726028FC9" modified="2019-04-10" version="1">MEAPEEEAVLEPDMQASEEEAVPEPDMQAPEEEAVLEPEMEAPEEEAIEAVFEPKIEAVFEPEIEAVLEPEMQASEEEAVLEPEIEAVFEPRLRSISSRDEAVLEPEMQASEERPSSNPRLRSSPTSEEEAVLEPKIEAVLEPEMQASEEEAVFEPEIEAVLEPKMQASEEEAVFEPKIEAVFEPKIEAVLEPKIEAVFEPKIEAVFEPKIEAVFEPEIEAVLEPEMQASEEEAVLEPEIEAVFEPKIEADFEPQMEAVLEPEMQASEEEAVLEPKIEAVFEPKIEAVHEPEMQASEEEAVLEPEIEAVFEPKIEAVFEPKIEAVFEPKIEAVLEPKIEAVLEPEMQASEEEAVLEPEIEAVFEPEIEAVLEPEMQASEEEAVLEPEIEAVFEPKIEAVFEPKIEAVFEPEIEAVFEPKIEAVFEPKIEAVLEPEMQASEEEAVLEPEIEAVFEPKIEAVFEPKIEAVFEPEIEAVLEPEMQASEEEAVLEPDSPLRPSSSPRCRLRGEAVLEPEIEAVFEPEIEAVLEPKIEAVFEPKIEAVFEPEMEAVLEPEMQASEEEAVLEPKMEAVFEPKIEAVHEPEMQASEEEAVLEPEIEAVFEPKIEAVFEPKIEAVFEPKIEAVLEPEMQASEEEAVLEPEIEAVFRARDEAVFEPKIEAVRARDAGFGGGGRRLRPSSSPRCRLRRRRPSSSPRLRPFSSPRLRPSSSPRLRPFSSPRLRPFSSPDWAVLEPEMQASEEEAVLEPEIEAVFKPEIEAVLEPEMQLRRGGPSSNPRLRPSSSRDEAGGGVLEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PK73</accession>
    <name>A0A3R7PK73_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Gustatory receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_012577</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002593">
        <property type="protein sequence ID" value="ROT69261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PK73"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050909">
        <property type="term" value="P:sensory perception of taste"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013604">
        <property type="entry name" value="7TM_chemorcpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08395">
        <property type="entry name" value="7tm_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT69261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="450" mass="49978" checksum="20F604E02749FE1D" modified="2019-04-10" version="1">MEIGFEGELSLLLYARRISSSPSEGDENTRRLSLSAARVGAEGASLCRSSPSLQKEQKEPRFASPLCRRSRRSLALPYPRTPSLLLVCFLAIVGMKCQIPSLLRRLSWGQQGCKWVICFCVWSLQLVGSFPYTWPGPPYQPRFSLWLCAWCVFMKIYCLFGVYVLFQVGGISLSDWTGSDLHGIIYKVSLMVYLCAYSQPHLVLLAKSRKLASILSRFAPFEEPVSQRRGVSPLILLQVLLLDFLIPAVALTFPSVPLLGHRLVMVLFAVLGGHSCFSAYLLFKALSVALSAYLVDAVEETLSPTLSEEGVSASLALPSLLLLEKRIRKVDETRRDLASCFFEGTSAVLLASVVGVIGSLFRFLVFGNQTDVYLQILMMNSYAIAGLCEVGQHFEDRIYRLLGFLEPLRKFNMCGWFTMNKTLFLSMGSVVLAYLVVLLQIGNQVSAGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PLP2</accession>
    <name>A0A3R7PLP2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mucin-1-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002414">
        <property type="protein sequence ID" value="ROT70521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="507"/>
        </location>
    </feature>
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    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
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    <sequence length="2119" mass="238052" checksum="10C266513F28D96D" modified="2019-04-10" version="1">MQTTLFLLENKAQCSEKAASVSPGLYSDKQPLRTAKHASSWLHHIYSNIRVGYNPNNNRPGYNHNSIRPGYNHPAHGSSRYVLQSHKAELSRHFTSPNNSNTYESPHSHHTVSTQSHKAQFQQSHSIIPQSHFTIPQSHFTISSTHTIPQFPQSQHSHTSTVTLHDSVTPPLQSHSTIPSHTPPFHSHTPHTVTFHRFHSHTPRFHSHTPRKFHDSTVTLHDSTRHTPIPQSHSTIPQSHSTVTLHDTVTLHIPQSHSHTVNFTVTLHDSTVHTHSTIPHSHTPHSTVTLPRFHSPHSRHTVTHPQIPQSHSTIPQSHTPHSQSHSTIPHHTPRFHTVHTPRFTVHTHSTFPQSHSTIPQSHSTIPQSHSHSTVTFHSPHSTFHSHTSTIPSQPRFHSHTSRFHSHTPRFHSHTPPFHSHTPPFHSHTPPFHSHTPPFHSHTHSTHTRFHSHTPHSTVTLHDSTVTHSSPQSTPQIPQSHSLHSHTQFHSQHSTIPQSHSTPHHSTVTLHHSTVTLHSSTVTLTSNSTVTLHDSHSHTPHSTVTTLIPQSHSTFHSHTPRFHKSHSHHSTVTLHDSTVHTQRFHSPHSTIPTVTLHIPQSHSTIPQSHSTIPQSHSTIPQSHSIIPTVTLHDSTSHTPPFTVTTPRFHSHTPPHSTVTLHIPQSHSHSFPQSHSTIPQSHSTPPPAFQHSHTQFHSTIPQIHPQSLHDSTAHFHDSTVTYSPLRITTLHHQHTPITIPPLHSTNHSPPQSHTQYSTVTHHTPRSTVDISIPHSHDSTVSTTPLKFQTVNTHIYPQDSSTVQVHSPAVTLTRSQSHTPRFSTLHRLTSPHIHDSTVTHYSTSTVTLHVHSHTPHFHSHTPTIPQSTLTFHSHTPTIPQSHLHVPQSHSTIPQSHSFHSQLHDSNSHTPLTHTPQSTVSTIHSHTPPFHSHTPTIPQSTNSTQSHSTIPQSHSNDSTVTLHIPQSHPPFHSHTPRFHRSHSTIHSHTHDSTHTPRFHSPLHFHSHTPPFPQSHSTFHSHTSQSTHSTVTLHHSTVTLHDSTVTLHIPQSHSTIPQSHSTIPQSHSTFHSHTPDSTVTSTIQSQHSHTSNSTVTLHDSQSHSTPFHSHTPRFHSHTPPFHSHTPRFHSHTPRFHSHTPHSTVTLTIPQSHHTVTPRFHSHTPHSTDSTVTLHEFHSHTPRFHSHTPPFTVHTPRFHSHTPPFPQSHSTIPQSHSTFHSHTPDPQSTLHDSTVTLHHTSHTPRTDVPQSHSTFHSHTPRFHSHLHIPQSHSTFHTVTLHHSTVTLHIPSHIHDSTVTLHIPQSLIHSHTPHSTVTLHIPQSHSTIPQSHSTIPQSHSTIPQSHSTQSTPRFHSHTPRFHSHHSTFHIHIQFTSHSTIPQSTLHQFHSHIHDSTVTLHDSTVTIHHSTVHSHSTITLHIHSHTPHPQSHSSTIPQSHSTIPQSHSTIPQSHSTIPQSHSTIPQSHSTIPQSHSTIHSHTPPFHSHTPRFHHTPRFHSHTPHSTVTLHHSTVTLHDSTVTLHDSTVTLHDSTVTLHHTLHHSTVTIHDSTVTLHHSTVTLHDSTVTLHDSTVTHTQHSTIPQSTTFHSHTPPFHSHTPPFHSHTPHSTVHDSTVTLHHSTTPPFHSHTPRFHPHSTVTHSNHSTVTLHIPQSHSTTVTHTVHTPRFQSHSTIPQSHSTFHSHTPRFHSHTPPFHSHTHTVTLHIPQSHHIPQSVHSTVHTPRFTVTLHTSNNSHTPRFHSHTPHSTVTLHDSTVTFHDSTVTLHLPQSHSTFHSHTPFHSHTPPFHITRRHTPPFPVTLHHSTVTLTTVTHIPQSTSTIPQFHSHTPPFHSHTPRFHTHIHDSTVTLHDSTVTIPQSHSPFHSSTVIHESHSTTQSHSTIPQSHHSTTHSTVTLTIPQSHSTIPQSDTPPFSHTPDPQSTPPFHSHTPHSTSHTHSTVHHSRFHSHTPPFHSHTPRFHSHTPRFHSPLTIPQSVHTVTLHHSTVTLQPFHSHTSTIHSPQSQSTIPQFHIPQSHSTIHHTFTHIHSTDSTVTLHFPQVTLHISQSHSTIPTVTLHLPQSHSTIPSHTPRFHSPQSHSHSRHTPPFHSHTPLHRPPLTSTPLTRSTKFRRGNNGGELHASGVKGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PPG5</accession>
    <name>A0A3R7PPG5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_008580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002080">
        <property type="protein sequence ID" value="ROT73019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
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    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018714716" description="Chitin-binding type-2 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="219"/>
        </location>
    </feature>
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            <begin position="24"/>
            <end position="93"/>
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            <begin position="161"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="219" mass="24142" checksum="841397705B8C734C" modified="2019-04-10" version="1">MLKHTGSLLLLLSLAVSPSVQLCAPDCMGVDPGTSVRDPTDCTRYYVCVDASGDGVLLPSEPVNCPDGQYFNEYHTVPRCDPISSAPSDFCSDLCNPCEPHCGSPGALTPHPTTCYKYYVCLQNDHYLEEECSPPNLYFDYMTGACQTDNSVCYTYCDVCEPHCTQQNERVPDPTDCHRFYLCTPPTMSNFLCPHNQVFNRATRECEDGAPCVVDCPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYW9</accession>
    <name>A0A3R7PYW9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003362">
        <property type="protein sequence ID" value="ROT63878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYW9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="826"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="609"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="621"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="832"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="898"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="979"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1057"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1080"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1093"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1139"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1159"/>
            <end position="1227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1243" mass="129183" checksum="6505D74CD3E329D5" modified="2019-04-10" version="1">MRKAERESKVETDQRAETHAARLSASTPASPRPRPPRRAAPPVPSAHAASPPFGRSSSTPASPPVPSPPTPASPPVPRPPRPPARALRYARQPPSRLHAPPPRPPRRPRPPSPPARRPCGAPRPASPPFVSRPAARSPVPPRPPSSAPPCQPPRVPPRPASHARQPARLGLLSRPPDPLRPRPLTPASQPRPSPSSARRSLGSSTPARPSPSHAAPSSGLHARQPAVPRPPTRAARQPARPVASTHAAVLGSPGLWPASPPSLASTPAAPPRPPRRRLLHPHALRSTPAPARPVAARRPPVLGLHAPARSLGTPARPRPPRPPAVPSAATPAPSLGSTPASPPVPRPPRPPVSSRTRPVPFRPSNLVSKSRNGSPIGLTCPARHSALSDAARPSASTPARPSASTPARPSASTPASPPVPRPPTARSPRAPRPPSLGHARPVPSTRLHARPPARPSASSLGLTPARAVGPSPPSLGLRSLGLPAPPLSLPRPSLASGTPQPVGYGLHARLRPARLATKSAVSAFHARARPSASSTPARPRPPARPSCRAPHVDPRRPRPSTARPSLGLARPLPARVRRSWARPALSGRPPRPPVLASVSARPVARLQRPARPAASTPGRPRAPRRPSRRLHGPPRPSLGLHAAPPVPRPQRPPPVLGLPARARALGHTPVSPRRPSTPAPRTPASRRAERTLVLPPVSAPRPARLWAPTRQSSALTARPPSPRSTPARPRLHARSAAPSLGLHARQPPARPRPPRPRIAPPVRCAPRGRRPSGLQTPASPSLGLRTPHPPVPRPLTPAAVPRAFLQAASPVLGLALIATPPPRTLFGRHAPARPSASTPRPALPRASWYAAPVPRPPPRSRRRFPPSASNAAPLPRPHARPSLASTPRPSAAYCRLPARPPAPPRTGPPVPAAPSAPSYPGPRRARPSPSPHARPTPATPPVPRPPAPGRAVLRPSTPASLHARHRPVASAPRPPPVPQASTPPVLGLSRARPSPRPASTPASPPVPSAYHARQPARHPRTSARPSLGAARPAPSAGPCPSASTPARPARSVPSGLTPAGPARPSASTPPARPSSASTPATPPVPRPPPRPPALSALQARPPSSAREPPARPSLGLHAALVHARPSSASTPAQSLGLTPPVPRPPRPPPVPRLHARQPVPRPHARPPVPRPPRPPARPSAPTPARPSSAPTPRPPVPRPASPPSTPARPFPVSPPASTPARPSPPRPVLGLHAAAPVHSIRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYX3</accession>
    <name>A0A3R7PYX3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003359">
        <property type="protein sequence ID" value="ROT63898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYX3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="550" mass="59164" checksum="632962FC88986D42" modified="2019-04-10" version="1">MTVCEVGSLLLPQHATYTQLLHPLPVSRLSRILTQSPFSHASSSLTITHHPVSRLSRILTPSPVSHASSPRLPSLTHPHPVSRLSRILTPSPSLTHPPVSVSRSRLPSLTHPHPSPVSHASSPVSRSHASSSLTHSHPVSPSLTHPHPVSRLSRILTPSPSLTHPHPVSRLSRILTRLPYLTSPVSHASSPSLPSLTHPHPVSRLSRILTPSPLLSRILTQSPSLTHPHPSPVSHASSPRLPSLTHPHPSPVSHASPPRLPSLTHPHPSPVSHARITHPHPSPVSHASHPSLSRILTPLPCLTHPHPVSRLSRILTPSPVSHASSPRLPCLTHPHPSPVSHASSPVSLLSHPHPSPVSHASSPVSRLSRILTPSPVSHASSNASSPSPVSHAPHPVSRLSRILTPSPVSHASSPRSLSHASSPRLPSLTHPHPVSRLSRILTLSRLTHPHPVSRLSRILTRLPSLTHPHPVSRLSRILTRLPSLTHPHPVSRLSRILTLSRLSRILTPSPVSHASSPRLPSLTHPHPVSRLSRILTPSPVSHASFSYRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3H7</accession>
    <name>A0A3R7Q3H7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative DNA mismatch repair protein Mlh3 isoform X13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_021331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000447">
        <property type="protein sequence ID" value="ROT85098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3H7"/>
    <dbReference type="STRING" id="6689.A0A3R7Q3H7"/>
    <dbReference type="OrthoDB" id="429932at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="3">
        <location>
            <begin position="433"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="677" mass="76453" checksum="ABE0C27C16EFD809" modified="2019-04-10" version="1">MSGKILPLSESVRSKLRSGITITSIAQCVEEMVLNSIDANATCIAVRIDPAIFRIQVVDNGDGVTEENLKLLGKRHSTSKCHSLEDLNSNLGHYGFRGEALASLVEVAAIVDITTRPRGSVQTLTKIFAYGKEKSISVSKVPRPSVGTTITVQDFMYNMPVRRKLMKEAIDIENIRTLVEFRDWDKLLLCIEEMVIKFAEEERLAISLDERYRRSGRDQVMAEEESQAEPHSSQALLQEMPEWTSSQPQGAPVLKIPLSEEPEAEGSRQKQDFVLTHGYSAFMSWKKRREMQKKEMEKSEIKISGCAYDSRDTQQDQYRQEAVSKEGEECESLISPGMKEAIQSILQDSEMDDDSIKWSEKPSNLGSLEEDSSEVAQICQEWEPPTFAMDADILSSKVQAGSERGVNKDSSVKIYNIVHPYKFSQEMLQTCRVLGQLDKKFIACEITYTSSDPTLHKVSEIIVLFDQHAVHERVRLETLTEENYETLENGERVIRTCMITPPLEMTLPESEVRLMMAYAKTFILWGLHFTQVSASQVNFQSIPSILVARERHELRQRRCQSATAIIESIVRDVCYTLHQTGGIVSTMPKPLMNVLCSQACRGAIKFGDELSYDECKNLVKSLSSCALPFQCAHGRPSIVPVVNLTHLAKGRKKERKPNLHKLREAIEEEMLGEEIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q3W1</accession>
    <name>A0A3R7Q3W1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peritrophin-48</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015022</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000288">
        <property type="protein sequence ID" value="ROT85403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q3W1"/>
    <dbReference type="STRING" id="6689.A0A3R7Q3W1"/>
    <dbReference type="OrthoDB" id="7250310at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051940">
        <property type="entry name" value="Chitin_bind-dev_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301">
        <property type="entry name" value="CHITIN BINDING PERITROPHIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23301:SF0">
        <property type="entry name" value="CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="42"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="144"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="203"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="261"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="340"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="400"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="488"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="547"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="608"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="663"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="722"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="865"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-2" evidence="7">
        <location>
            <begin position="924"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="812"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT85403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="998" mass="108285" checksum="B761DBE90156DA98" modified="2019-04-10" version="1">MPICLDGAVYSYSCPSGEGLGYGSESCRPAAEVTCPRLPPSTPPCLNQTNGYYPDYTQGCRGYYRCDNGSVNGRWFCENSGLWDVATGSCGSGSGLTCTPPSCWGLPDGPHPTPASSCTAYFTCQAGVRTDHRCVPSSSSVCYEQACEGRVNGFHAAPHASCRAFFRCFNGALVELQECPRHQIFDGQRCVSATNFSCWGEGRGSCEGRDDGLFAASDCRGFFRCRHQQFIRAFLCSRGLVFNGRECVEDTNALCTSQAPRPDCANKIDGYYTVEKTGCRTFFSCRGGRKISEHTCPGTNVFNGEQCVDPVLYPCPASRPPLAPLAANLTNRVARSLSADADCASRPNGYYLDVPSRCTRFFYCHEGAKQFVRSCPPGERFNGLGCVSQDSYKCPVIAGAPECLLRGDGVYQDLESGCSSYYQCFSGVKIEFKCPEGRLHSGRACEPAAQVFCPAATLCSHQRLNATLVFNGKECVPHFFYTCPARVSTACLAKPDGLYQDLSTRCRSFYECRAGERVSTRTCGDEEVFNGEVCVPTASYVCPVDGAKECGAGRKGFVQDIQSGCRRYYYCYAGKSFARECPAERVFNGHTCVPSAQYRCPSGPKGERPRCSGPDGYYPDLHTSCRSFYYCRDGLRINYTCPEGEAFNGVQCVPEAAFTCSSPSSCQGKINGFYQDVFAGCRKYYYCHGGVKYAHTCPGEQVHNGRTCVPASTYTCPSPTDDRDCVGKFSGLYPDLSSLCQVYYQCQGGVKTQTLACPQSQVFNGYKCVPFYEFSCSSLGLVSPSSPARLDLPPDQLLAEVGAPVANALQVSLGASGRPPPSAQHSASRDDAPSPPDQAVESSGTAATQLLDPLAAPSRTSSPSSPLCEGLPDGSYTDVSAGCEEFVACRQEKELHSRCPEGNLYSPISGRCERRDVITCPEHINPCESLPDGVHGEVESDCRVFFTCRARRMHLVSSCPEGMAFDQRRGECRPESQGGCQKPLEAKSRQAGKFRAVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q8V2</accession>
    <name>A0A3R7Q8V2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002282">
        <property type="protein sequence ID" value="ROT71537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q8V2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="663" mass="69713" checksum="74DA342BB1A4377B" modified="2019-04-10" version="1">MRLESAMRVQIKRSLCLIYTGWGAGHGLPTHAFKVDPSPRFQGDYRPYWLAGREGEGGYLYDESHSPQPQTPPNTSHSFTLISLLSLLTSFLSLPFVSPPSPPHSPLFPSLHPHLYHIPLPTSPTHFPSLPFLPPTRPSLTSPPPHSPSRPSLLCHTHPPLFPLHPLHLSHLSSSPPHSPPSSPNPSPHPLSLHQIIYSLPPHSPLSSLPPILLFPISLPSPLLPPLSPLLSPPSPPPPSPSPPTPLTPRLFLHPFSLPSLSFHPLHLPHLSLSPSALPLCSSHPNPPHSPTSPSPPHCLFLPPCPHSPSLPPTSLHLSPSSLPPPHSPPSLLSLPTHPPLSPPPTPSPLPLSPSHPFLSQPLPSPPTTNSLPPPSLLPPHLSPLSLPSTPLTPLSPSLPAHSPLSPSLPPLHLTPISLHPLHLSPPLSLPLTLSPLQPTHPLFLPPCHSPPSLPPLPSPPLSPPHSPPSPPSHPLTPPPSLLHSSRPPSPTPFSLPPTPLTPLSLPLHLSPSLPPPPSLSPSLPPLPPTHPLSPSPPCPLPPLSLPSHPLPLPMRHVSGQVARRPESASADGSRVSGNSGQVARGVSLAAVSGQVASRWLAVTGGFAGSVSGQVARGVSGQVGSPGSADRWARVSGQVARLRSAEQVARGVSGQVARRERSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q9B1</accession>
    <name>A0A3R7Q9B1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative cap-n-collar isoform X5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002243">
        <property type="protein sequence ID" value="ROT71807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q9B1"/>
    <dbReference type="OrthoDB" id="8121163at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="257" mass="28309" checksum="160DC6B800FBEB07" modified="2019-04-10" version="1" fragment="single">IAFGKMEGPVIEELPVMRSLSPSTVFGEPIEIDFSQTLIQDPSKVVQITPSQMSVSSPEKSRKRKKQSKKDLALIEALWKQDVDLGVPREVFEEDGLEPPVDSQTKDKDHGKNPKSETKIDEKPDENPWMHFNFTIDSETGEHLLSTESPISGGDVTLDPVSPLSPPSFTLNESVPDFNLEFNLDEALKLVGLNSSETGEAVWKSVETDSSSEDFAKGFSEEEKASDGGDSLDALSDTLDEMIQASQLNPHHPRSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QAL9</accession>
    <name>A0A3R7QAL9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Treslin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_008642</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002086">
        <property type="protein sequence ID" value="ROT72975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QAL9"/>
    <dbReference type="STRING" id="6689.A0A3R7QAL9"/>
    <dbReference type="OrthoDB" id="6341942at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030174">
        <property type="term" value="P:regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010212">
        <property type="term" value="P:response to ionizing radiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026153">
        <property type="entry name" value="Treslin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053919">
        <property type="entry name" value="Treslin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053920">
        <property type="entry name" value="Treslin_STD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21556">
        <property type="entry name" value="TRESLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21556:SF2">
        <property type="entry name" value="TRESLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21854">
        <property type="entry name" value="Treslin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21855">
        <property type="entry name" value="Treslin_STD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Treslin N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Treslin STD" evidence="3">
        <location>
            <begin position="636"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="788"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="918"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT72975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1103" mass="120852" checksum="5C31984CED0CAA3B" modified="2019-04-10" version="1" fragment="single">MFSSVQAVFLIDVNSFVGLSNNESELERNVARLKLGCLKLLTEFGARTEKGSEEVRWSCKYYDSLSFRPDTTRKSFVDFNRSSFDEFENDVTDRFCKAFDTKQAPGEQPLAGEPGKPHCYILKKALQEVLLDYNWDRPDISSPVKTNRRRTKGGQSKLLPENVGPYNSVIVCTRVPHSLEDVRLFCGCDSEAAEAQVTAEDFLGTVVDPALLKGFQEDKQIHLNFINVSDAPNTAAVDPRVTSTINAGLSKLSGSLHPLSNIVQSDAVQIAASDKVPEAGGIFPSPPVCVAGIGVQVTWWKKARGARPRRPQPGPFLVWEDAEGISYLKVQLEVLAVHGSSSQEWGNAVVVGVVRTSAVSVLAVAGGTGHLYVCHAPNTVFTTLISVLAKYQLSVLLKLNCGGVAVLCPWAGGVGCLAVISASGLATPPLHSQAASQETRITDPGLLNFVAQTVEKCLKNASPHMNGETIVTTKRFSAHQTERWYRPLKGSSDAVKEIRRKRANRMERKAMQERLQKRYRPQIPCPLSAGEMGPVDLVDVTQPLGEAGPSKKPTMSRAQQLVKKSHIVTAQQKVKEQRAEEEERVQATERRAAQASEQARKSQALESQVLNKVSDIQDTEKLIQTLKNLCNGDGIETDLFTSAQTVINLALMHVKNNCGKDMEGGLRKLLGSGVIQTTVDINNEHPAESHLHHYKLQTLLHLELLWVLGYSSSSQMEDEEESRGSSIREHHVEEAVKMLRAISLRHNPTTMATLGVGPLKILTGDLSSVADTRPNSVKSHASSVVSYDSTCGSVENPGSGKSREGRRMSSRHPSLKETSKRTIVIPVVTRALRRTNSEQTKQAAAPPASVANKASESADNDIKKVCRNLFDLSDGAAPKPKLQRSMTVGSVPVAELRRSPRKKHRKSTAITPRKSRMLMKSSKGSHKTPVKGMRTAEKGMKTPKSKKGGVIVPETPGDKVGQTMFNKRRIRKSTGTTLVTESPDIKRVSKTTPRRLQASLTITRRNSFYSGARSRNWERGKTQLLADHIRSHSERRSLDSSALQSVGDASFLFSEILSASQSELSHQDSTSNNKDHNDAGTPERRVLDYGLDTSTEVEESSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QCR1</accession>
    <name>A0A3R7QCR1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">B-related factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_018658</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003438">
        <property type="protein sequence ID" value="ROT63446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QCR1"/>
    <dbReference type="STRING" id="6689.A0A3R7QCR1"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20553">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000002">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000007">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="14">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="484"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="293"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="532"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="569"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT63446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="580" mass="65239" checksum="45ABFBED07A2DFA7" modified="2019-04-10" version="1">MSSRCQHCGCGDIDIDPARGDAVCTSCGTVLSEHNIVSEVQFLENSHGGSSAVGQFVSSDAGGKRPMFRGYNGTFARESKEITLNNARKRINALAQQLRLSQHSIETSFNFFKLGLSKGLMRGRKNNHVIGACVYITCRTEQTPHMLIDVSDALQIDVYELGRTYLRLSTALCINIPAMDPCLYIWRFAHKLSFGDKTHEVSETALRLVKRMKRDWMHTGRRPSGVCGAALVISARLHGYNRTINDVIKVVKVHESTLRKRLTEFGETPSSALTPEEFMTMDLDEEQDPPAFRAARKREKERVQKLLDEQEDLDSELTVLQQEIEKHLEERKRKLRGIWAKYDREEETTEEESVEQESADTQKFITEATLQTIDECLGENGDEAIKPELKVQGIGPSAASLGLKETIEECMEIRPNDPEPEDRGVLDLSGIDEDEIDSYIMSDREIKLKTELNAPANTAGEAIEKMLMEKKLSNKINYDVLRSLKGEDTGGGEEDIKEEKPSPKTLKTIPVETPEGISSVLHSLTGKRPRNSIKEEGEKSPKKIKGETTDAANTSLGPKLLRRRRGEDNSYDDYYDDYYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QEJ5</accession>
    <name>A0A3R7QEJ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leukocyte receptor cluster member 8-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_005159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001677">
        <property type="protein sequence ID" value="ROT76265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QEJ5"/>
    <dbReference type="STRING" id="6689.A0A3R7QEJ5"/>
    <dbReference type="OrthoDB" id="199574at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.990:FF:000010">
        <property type="entry name" value="Leukocyte receptor cluster member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="275"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT76265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="441" mass="50133" checksum="48767B4AD3599278" modified="2019-04-10" version="1">MTGLVANGDWPESLKTYVSRCFKRCVTELDKDLVEICLKGKLTQAANNGTLWTKNWEEEELPSIQSESTSNIISHIKSWNTGTDAGSDNSSSSPMKLQGKKGMKKNITPAFGSMRGMRNESYFYSKHGRMSLDPELGSSERLQKRAARFSVAGSGPGPHKKRKPINLTKTISNTFTVDGDDIDWTSMHIVGTSTSLEKQYLRLTSAPDPSTVRTIDTLKRALEHIKCQWVRNQDYRYACDQLKSLRQDLTIQGVRDAFTVQVYETHSRIALEKGDHEEFNQCQSQLKQLYSEVGGDNHLEFIAYRLLYYMFTKNTLDITSLMAGLTKEQKQDECISFALQLRAAWSLSNYHRFFLLYRNAPKMAGYLIDWFADRERKQALKIMLKGYRPGSLDVSFIRSELALGTQEDWQKFESAVNLVYTDTSKVRIDCKSSTADSVATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QPR1</accession>
    <name>A0A3R7QPR1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001939">
        <property type="protein sequence ID" value="ROT74084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QPR1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="44707" checksum="A58A6B4032D94559" modified="2019-04-10" version="1">MRRLGPFLPIRVLFEAISTDCNITRTCGSDLHGSGRGLVEKAFDTEAAIAPFRLSLGPASCSCTFDSVFDLWPPLYLSVYQSSLSSLFFCPPPLLASLLSFPLSPLLPLLLFSSPRSSSLSLSFFCPPPPSLSLLSFLSLSLSPSFTSSLLASLLSFPLSLSSFSFALLLSSPLSSPSLSLLSSFFCPSPLLASLLSFSSLLLFSLLLSSLLSLLPTLSSSSCSSSSSSSPSLLSFLSLSLSFFCLLLLLASLLSPSLSSPSRLPPLSLFTLFHLPCSQSLFFSSPFLFLPISLPSPLLNPISPVPIPFSLTFSSSRPSFSLFLLPSLLFLHHHPSLPFLISIHSSFPSLPSLPPSLPFLFPFPSSSPFLPFFSSFFLPCSPSPPSYQHPPALLPAPPLLPAPLLPPPPLPPPIKHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QQM9</accession>
    <name>A0A3R7QQM9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_006726</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001849">
        <property type="protein sequence ID" value="ROT74772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QQM9"/>
    <dbReference type="STRING" id="6689.A0A3R7QQM9"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.10:FF:000004">
        <property type="entry name" value="Ubiquinone biosynthesis protein COQ9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048674">
        <property type="entry name" value="COQ9_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21392">
        <property type="entry name" value="COQ9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="12" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="Ubiquinone biosynthesis protein COQ9 HTH" evidence="11">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="COQ9 C-terminal" evidence="10">
        <location>
            <begin position="180"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT74772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="286" mass="32125" checksum="35CAFA5E4BC22CF1" modified="2019-04-10" version="1">MISTRHLLIRAFSIARHSGYSRGLSTSAPRWSKEETAQSEGTSTGQDAFESESSSEEDFDAGEDQLRAEILNAAMPFIYSHGWSQEAIAQGAETLGYSGMAHGMFPKGGVELVNHFYATCNNRLEEHLAAKAKEIENNPELKKGTTAFIAESVEERLRMNIEYLDSWHQALALHASPVNIPEALDNLGRLVDHIWYYAGDRSHDFNWYTKRGILAAVYKSTELYMLQDKSEDFEDTWAFMNRRLSDVHSIAKCARNADNVTKDIRNVVKAGLLTALNIVGMNDRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QXZ6</accession>
    <name>A0A3R7QXZ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_024250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000801">
        <property type="protein sequence ID" value="ROT82588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QXZ6"/>
    <dbReference type="OrthoDB" id="6161578at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061564">
        <property type="term" value="P:axon development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016360">
        <property type="term" value="P:sensory organ precursor cell fate determination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19715">
        <property type="entry name" value="bHLH_TS_amos_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000025">
        <property type="entry name" value="protein atonal homolog 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF162">
        <property type="entry name" value="TRANSCRIPTION FACTOR ATOH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="4" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="9">
        <location>
            <begin position="160"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="64"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="71"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT82588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="217" mass="23105" checksum="E3792306A409D8B9" modified="2019-04-10" version="1">MSVSEWYFPASRPALPGPLAADALYLDQLSCASPAYSSPPYTTGSYGLSAQCASAVAPQEPELWNSTEGASCSDGRPSPSSSPVSSCESMEGGSPHTWSSHGSGPSSWSWGAPGTTHPVLAAVSDLSAADSPVVVAASRRSQSKSRRRPPKSVGREVIKRRRLAANARERRRMNGLNNAFDKLRDHIPALSGDQKLSKFETLQMAQTYISALVELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QYW1</accession>
    <name>A0A3R7QYW1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_022854</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000614">
        <property type="protein sequence ID" value="ROT83965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QYW1"/>
    <dbReference type="STRING" id="6689.A0A3R7QYW1"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018698175" description="Protein kinase domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="146"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="446" mass="50250" checksum="E28D6D235A52A97F" modified="2019-04-10" version="1">MVARYLLRFGLLSGGAVVAYNGDEVQTAAIGGLRFGRAAVAVVKIVADYRNTLYSGTITPESPEYAEVKSQTHLRAANRLLDLCCANGGAFVKVGQHIGSLEYLLPTEYVETMKVLHSSAPKSPLENVYQVLREELKCEPKELFVEFDPNPLGAASLAQVHRAKLTDGREVAVKVQHPSVKAHADIDMKGMELLVNVVAQIFPDFSFKWLVEEMKKNLPKELDFCYEARNAEEVARQFYHFPWLKIPSIDWNLTTSRVLVMEFCQGGQVNDRNYMTEHGINTREVSEKISKLYSEMIFVNGYVHCDPHPGNVLVKKNGNSAEIVLLDHGLYTNLTNDFRVTYSKFWLSILNADLKEVQKYGEQLGVGELFGLFACMVTARSWDSISRGIDKKERSSDEQDEIKADAAKYLPEISAVLNRVPRQMLLIFKTNDLLRGIEFSLNTQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QZ60</accession>
    <name>A0A3R7QZ60_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000557">
        <property type="protein sequence ID" value="ROT84352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QZ60"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="412"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="563"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="578"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="696" mass="75472" checksum="95944438B78C9AB7" modified="2019-04-10" version="1">MRPLLRCTSIYTLPAPFQPAQLQHQHPCQHPSTTSTHSPANTLPAPTPTPLPTPFHHLDPLPCQPFQLQHPHPANILPPPRPTPCQHPSSSAKHTTSTHSPANTLHTPANTLHHLDPPLPTPSSSNTHTPANTLPPPRPTPLPTNTPPPQHSNQHPCQHPSHHLDPLPCQHPSSSNTHTPANNPFHHLDPLPLPTPPAPTPTPLPTPFHHLDPLPSNHPSQHPHPPTPFHPPRPLPQHPCSNTPTPLPTPSTTSTHSPANTLPAQHPTPANTFHHLDPLPTPSKLQHPHPCQHPSTTSTHSPANTLPANTHTPANTFQHSTHSPDPSQLQHPHPANTLPPPRPILPTPFQLQHPPLPTSFPTSTHPLPTPLPTPFQPPTPPCQHPSTTSTHPLANSNTHTPANILPPPPTHQHPSSTSTHSPANTLPAPRPTPLPTPFHLLPHLHSPHSLPTLHHLDPLPANTLPAPRPTPLPTPLHHLDPSPAKHPSTTSTHSLPTPFTTSTHSPAQHPPRLTLHHLDHSPANNTLPSTLTTSDPLPCQTPFPSTSTHSPDNTLHHLDHTPPANTLRSTSTHSPANNPLPTPPSTTLPTTPPLPNTLPPPRDPTPAKQHLAPLRPTSPCQHPEPLPCPNHHQHLDPLPSFHPPRLQRPFGTSTSTHSRQQRFQLRNTHPCYHPSAPRPTPPAKHQHLEPTPLPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7R061</accession>
    <name>A0A3R7R061_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000234">
        <property type="protein sequence ID" value="ROT85602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7R061"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="402" mass="44547" checksum="6948095738312AE9" modified="2019-04-10" version="1">MQCPVAAEARNGTQGHNALGERSTGGVGVTDCFARALTPRLALRFLGLLEMSLAPGPLSVSSSPLPFSFSLFASASFFFSRFSLFLSYPSVFYPRSVSFLFSQLPFSIFESIISFFSLSHLFPPLFLSSPHFPSLSSYLHFPFLSSFLHFPSLLSYTFPSSKSPLPPPSPHISNLLGLFPFPSLPSLPPPPSLLPSISLLNLPSFFPPPIPSRSLPSTLYPLFSSHFPSFCPFTPPLYQPLHGDKTASSAFVSRHKRGAMSQRLRSQRGRGSCPALQGLRQERSETPRVGPTKEEEPAPKKGQKRKDVGMEGGEGRTRKKMKEEDDWGRDYYAQFDIYYEKADPSPHVSLKFCGQSVPFIVDTGSLDSYISREQARSLNLTIEDTSYGDEYVMGELSINKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SIN3</accession>
    <name>A0A3R7SIN3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ionotropic glutamate receptor C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_019508</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003579">
        <property type="protein sequence ID" value="ROT62633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SIN3"/>
    <dbReference type="STRING" id="6689.A0A3R7SIN3"/>
    <dbReference type="OrthoDB" id="6340587at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050906">
        <property type="term" value="P:detection of stimulus involved in sensory perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052192">
        <property type="entry name" value="Insect_Ionotropic_Sensory_Rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643">
        <property type="entry name" value="IONOTROPIC RECEPTOR 20A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42643:SF24">
        <property type="entry name" value="IONOTROPIC RECEPTOR 60A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="370"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="454"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="503"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Ionotropic glutamate receptor C-terminal" evidence="11">
        <location>
            <begin position="384"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="269"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT62633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="684" mass="74194" checksum="19E8E876999EC369" modified="2019-04-10" version="1" fragment="single">PLPLPPSPLSPPAFPSPLLTPASQRPPSFSLCTTLLSPPLPSPLNAPAHPSPPSPLTPPLPCSLCTPSQRPLSFSLLYPLCNPSSFLFPLYPLSPPPFLLPLNPLSPPPFLSPSSPSNPSHSSPSAPLPPPPLFLLPLNPPLTLPFLFPSVPPPFLLLPSLSTPPFPTLTPLPLLPLPPLPPFLLPLNPLNRPIPSPSVPPLTPPLSSPSAPPLTPLPLSFYLPLPLTPPPFLLPLHPSSPLPPSFSLCTPSHPSPPFPFSLSPPLPLPFPSSGGRVHRAARDGVEPPGGDRRLLDPSGHHHLRNPRPPPRLRAQAGRPAQALQRGSFLAQNLNQTQPPDTTRRPLEPEEETPFLSETLRFNPLRSCGYLSLLLIVAASSFTIVWLWILAMMGIMGPLIYLIILLRVRLCRGDPTLTRTFPLDQCVWFVFGAMMKQGSVLSPISDSSRILFATWWLFITIVTSFYTANLTAYLTFNSLVLPIEKAEDLAKYPDIKWVAFRDGALADIIMVGMGYGGIIMVGVGYGGIIMVGVGMGYHHGGCGSGGIIMVGVGSGGIIMVGVGMGIIMVGMGLGCHHGGCGVWGIIMEHPKLKVLRDMREAGRGAFLSSHKEALDLVRGGKHVYIDDMRILDYLIQEDFKARRSKGEKDQCHFYATPLDKDKDFIFWYGYAFRKNSEYKDLFDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2024-01-24" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SJH2</accession>
    <name>A0A3R7SJH2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018507</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003414">
        <property type="protein sequence ID" value="ROT63605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SJH2"/>
    <dbReference type="STRING" id="6689.A0A3R7SJH2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="416" mass="45454" checksum="2328E5E9C8D2D30D" modified="2019-04-10" version="1">MGVFGELKRDCQDLSTASKSDIWPACLSPRSRVCAEDAHGANWNSQTAWRQVSSGSTSHGSQNPPEFVEIDVPKCEGTGPLPRRVGYRTLLAVLGSPLQGDGTRVPRPFQPLDAIAREQVIALFSTHGKTYPPIHAATLHLFFHSLRLSPFLHPFPITSLNPSYTPAPTPTSHFATLLHPSPCNDIYHFPTPEPLNPSSTSPPLHPPILNPFFHSPHLPIPTNPSSPCPLSTFHPEPLLPLSPLPLCPHPYQPLLHPVSLFHFPTPYNPSSTLNPFFHSAHPIPINPFSTPVSPLPLSHPHPLPPEPLLHSLLSTPSPLFPLPLFRPTTPLHLNPFFTLPTSPSLSTPSPPCFPSSTLPTPYNSSSTLNPFFHSPHLPIPINPFSTLFPLFPSSTPTTPLHPEPFFHSPTPTPLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SMC5</accession>
    <name>A0A3R7SMC5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">limulus clotting factor C</fullName>
            <ecNumber evidence="9">3.4.21.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">C7M84_014980</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="14">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Selective cleavage of 103-Arg-|-Ser-104 and 124-Ile-|-Ile-125 bonds in Limulus clotting factor B to form activated factor B. Cleavage of -Pro-Arg-|-Xaa- bonds in synthetic substrates.</text>
            <dbReference type="EC" id="3.4.21.84"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.84" evidence="9"/>
    <dbReference type="EMBL" id="QCYY01002871">
        <property type="protein sequence ID" value="ROT66980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SMC5"/>
    <dbReference type="OrthoDB" id="6342449at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042381">
        <property type="term" value="P:hemolymph coagulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000120">
        <property type="entry name" value="Putative serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0353">Hemolymph clotting</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 12" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0768">Sushi</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018561536" description="limulus clotting factor C" evidence="12">
        <location>
            <begin position="18"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="13">
        <location>
            <begin position="215"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROT66980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="448" mass="49010" checksum="41D0F840758D76F9" modified="2019-04-10" version="1">MQKINVYLLSLILAVLLLEEYKRKRKDKDKNEKEADVALRFSPRNFRMAQCKVTYKMEEEEAFLMTTDSSKQSRKCDSKFVAPKGHRLNFTCPVFNLAPTGCRQEKLIVKDSNLKMTFCTNDNVDLASSGTSLNIKHKRKKTKSKECTGTYVCEVTVVREDLDSSSGDGTGGQSASVTTDPSNSASTTTVTSPAASQDRHFCSNCGISQITVPRIVGGQDANRGEFPWQVGIKLSWGGRCGGSLIKPRWVLTAAHCYMSGFTSTTVYLGDHDRSVNEEGSFEMQAASVTVHPDFDSLTLDNDIALLKLSSPVTFSSTVAPICLARPSEVPQSGVGITTGWGTTAWQGSTATVLQKVAVDYISNAWCTQLYNDRFDITDNMVCTYTPKKDACQGDSGGPLIARAADGRWVLTGVVSFGDECAKKDSPGVFTRVPNYISWIEENTPDDDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSF9</accession>
    <name>A0A3R7SSF9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008603</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002085">
        <property type="protein sequence ID" value="ROT72977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSF9"/>
    <dbReference type="STRING" id="6689.A0A3R7SSF9"/>
    <dbReference type="OrthoDB" id="3800936at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12249">
        <property type="entry name" value="RRM1_hnRNPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12250">
        <property type="entry name" value="RRM2_hnRNPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000023">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein q isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000024">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein q isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041337">
        <property type="entry name" value="hnRNP_Q_AcD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006535">
        <property type="entry name" value="HnRNP_R/Q_splicing_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01648">
        <property type="entry name" value="hnRNP-R-Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21245">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18360">
        <property type="entry name" value="hnRNP_Q_AcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="157"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="238"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT72977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="352" mass="39443" checksum="EB5325806F36DB4B" modified="2019-04-10" version="1">MAEGNGGGDPGSQVDGERTEDYQKLINYGLNEKVAAKLDEIYKQGKLRHEDLDERALDALKEFPVEGAVTVLKQFLESNLEHVSNKSAYLCGVMKTYRQRKQYNTDSMTVNPGKGPDEDNLKAILERSGYTLDVTTGQRKYGGPPPNWEGPPPGPGCEVFCGKIPKELYEDELIPLFEKCGEIWDLRLMMDPMTGQNRGYAFITFTTRAAANEAVSKLDNYNVRENAALKVNISIPNLRLFVGNIPKSKSKEEIMEEFSKRTAGLVEVIIYSSPDDKKKNRGFCFLEYESHKAASLAKRRLSSGRFKVWGCEIIVDWADPQEEPDEDTMSKDACAPSHAAWWAGRGSRGRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7STU0</accession>
    <name>A0A3R7STU0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial-processing peptidase subunit beta</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_006669</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="QCYY01001843">
        <property type="protein sequence ID" value="ROT74807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7STU0"/>
    <dbReference type="STRING" id="6689.A0A3R7STU0"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000002">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="16">
        <location>
            <begin position="56"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="17">
        <location>
            <begin position="208"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT74807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="52967" checksum="A7CC219E4987E910" modified="2019-04-10" version="1">MSRLLRPAGALLKNYSNKSFLVKNVRYRGTIAAASYEQTLLNVPATRVTVLDNGMRVASEDSGAPTATVGLWIDTGSRFETDANNGVAHFLEHMAFKGTSKRSQTDLELEVENMGSHLNAYTSREQTVFYAKCFSEDIGKAVEILSDIIQNSKFGEAEIERERGVILREMQEVESNLQEVVFDHLHAVAFQGTPLGRTILGPTKNIKSISRADLIDYITTHYKGPRIVLAGAGGVNHETLVKMAEDNFKSLGGSYVGDAPEVAPCRFTGAEIRVRDDSMPLAHIAISVEGAGWSDPDNIPLMVANTIIGSWDRTHGGGAHNASNLAQAAVVGNLCHSFQSFNTCYKDTGLWGMYFVCEPLKIEEFMFNLQSEWMRLCTNVTDFEVERAKNILRTNLLLQLDGTTPICEDIGRQMLCYNRRIPLHELDARIEAVTADVVRDTCYRYIYDKCPAIAAVGPCEGLPDYNRVRSSMYWLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7T054</accession>
    <name>A0A3R7T054_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NMDA receptor subunit 2 variant B1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_023100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000641">
        <property type="protein sequence ID" value="ROT83727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7T054"/>
    <dbReference type="STRING" id="6689.A0A3R7T054"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015683">
        <property type="entry name" value="Ionotropic_Glu_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18966">
        <property type="entry name" value="IONOTROPIC GLUTAMATE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT83727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="328" mass="37242" checksum="49338EF5D61B586D" modified="2019-04-10" version="1">MTPLSPPSLLPPSPFPPPSPSPDAPDAFLYDATVLDYLVGQDDECQLLTVGTWYHMTGYGIAFPRGSKHTAQFNERLMSYKDNGDMERIQRFWLTGACKPKKQNKRASEPLALEQFLSAYLLLFSGVLLALILLLLEHFYFKYVRQHLAKTDSGGCCALISLSMGKSLTFRGAVFEAQDKLRRHRCRDPLCDTHIWKVKHELDMARVRIKQLEKELESHGVKPSRKFASRQGNILTSCWKPRTNDEGEGEPVPQILNVYARSRHLRYDVLTPPPLTIPSPSSPPCYSPPPPHLPLKKEKDTHPQEYRPPTHLPKPSPTSLASYLQDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S8X7</accession>
    <name>A0A423S8X7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mucin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004678">
        <property type="protein sequence ID" value="ROT60607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S8X7"/>
    <dbReference type="STRING" id="6689.A0A423S8X7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT60607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="40675" checksum="403D90DD66A59802" modified="2019-05-08" version="1">MAKARLPDPTCCARVRPPPPPSSPAFSPFPRSHSKPPQTAPSLNHSLRTSPNSPFPQSLTQNFPKKAPSSITALNFLIQPLPPLNLHSPTPRPLNLYSSTQQPLNLHSPSSAHQSTAAHPLHNTSAFKPKQPHPSITRSELPQTAPSLSHSTAPQTPLTHSTAPQPPPTHSTAPQPSLSHSTTLETPLTHSTAPQTPLIRSTAPQPTHPPQPLNLHSPTPQPRNSTHPLHGPSNSTHSLHSPQPPPTHSTAPQPSLSHSTTLETPLTHSTAPQTLLIRSTAPQPPPTHSTAPQPPLTYSSAPQPLLIHSTAPQPPPTHSTAPQSPPTHSTVPQPQLTYSTAAQPSLSHSIALGPLLTSLTHSTAREPLLNHSTAPQPLLTHSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9Z2</accession>
    <name>A0A423S9Z2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004418">
        <property type="protein sequence ID" value="ROT61024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1185"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1211"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1239"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1265"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1293"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1320"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1467"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1701" mass="185286" checksum="1A6B066476DB53A3" modified="2019-05-08" version="1">MSQRHLRRPSARVRLSANLPDGKRKERRHLQRDPRRGASSANCNLISAICDGPRRGSGSRLTYLRGSERKGAICSVTRDEGRPRLTATRLIVLQRHLRRPSARGLRGGFLGVNTVHHLWILVEEFQRTSGSSSVLLGSFPFPFEISEEGFLGVSAVLLWISEEEFLGVGGVLLEISEEGFLGVIGVYLFYEFLEASDVLLEIYEEGFLGVIGVYLFYEFLEASDVLLEIFEEGFLGVSVVVLGIIEEEILLYDHVLTGIFEEVFLADSGDVKGPGVSVVVLGIIEEEILLYDHVLTGIFEEVFLADSGDVKGPGVSVVVLGIYEEGFLGVSVVVLGIFEEDSLVSAASSLGSSRIVGNRGIAKKDFLRVQRISEEGFLGVSAVLLWISEEEFLGVGGVLLEIYERDSWGQRPSPLDLRGGIPRVVASSSRSTRRDSLGSAPSSSGSPRRNSRVGGVLLWISEEEFLGDVLLEIYEEGFLGVIGVYLFYEFLEASDVLLEIFEEGFLGVSVVVLWISEEEFLGVGGVHLWIFVEEFQRTSGSLLATSRPWVSVVVLDHRGGDLAVRPRPNRDFERFFLADSGDVKGPGSAAPKRSPEEEILLYDQVLTGIFEEIFLADSGDVKGPGVSVVVLGIYEEGFLGVSAVLLWISEEEFLGVDGVLLWISEEEFLGVGGVLLEISEEGFLGVIGVYLFYEFLEASDVLLEIYEEGFLGVIGVYLFYEFLEASDVLLEIFEEGFLGVSVVVLGIIEEEILLYDHVLTGIFEEVFLADSGDVKGPGVSVVVLGIIEEEILLSFPREWRDVKGPGVSVVVLGIYEEGFLGVSAVLLWISEEEFLGVDGVLLWISEEEFLGVGGVLLEISEEGFLGVIGVYLFYEFLEASDVLLEIYEEGFLGVIGVYLFYEFLEASDVLLEIFEEGFLGVSVVVLGIIEEEILLYDHVLTGIFEEVFLADSGDVKGPGVSVVVLGIIEEEILLYDHVLTGIFEEVFLADSGDVKGPGVSVVVLGIYEEEFLEVSVLFWTFNPEDDDADPDELLEDPEVDGAALEEFLLDEARALDVATVREENLLEDPGGRENRGVRVAKGDPYQPALGQRLPGLAEEESLGVSGVLPGLAEEESLGVSGVDRGGRIGVSGIHHLPIFVEEFQLTSGSISVLSGNYPFGVIGVYLFYAFLETSGVLLEIYEEGFLGVIGVYLFYAFLEASGVLLEIYEEGFLGVIGVYLFYAFLEASGVLLEISEEGFLGVIGVYLFYAFLEASGVLLEIYEEGFLGVIGVYLFYAFLEASGVLLEIYEEGFLGVIGVYLFYAFLEATSGVLLEIYEEGFLGVIGVYLFYAFLEASGVLLEIYEEGFLGVSVVVQGIPEEEILLYDHVLTGIFEEVFLADSGDVKGPGVSGVVQEIPEEEILLYDQVLTGIFEEIFLADSGDVKGPGLVEQEFLEGSPVYLGIFEEDFLGVSGVLHGISEEELASSGSATSSGSATSSSSGSATSSSSGLAEEEFLAAGGVHQIAFIKALRLRYDQILTGIFEEVFLADSGDVKGPGVSVVVLGIIEEEILLYDHVLTGIFEEVFLAASGDVNGPGLVEQEFLEGRPVYLGIFGVSGVLHGISEEELASSSSWGSSASLGDVRFLGVSDVRFLGVSDILFLGVSDILFLGIFEVEFLEFLTQGVTIALAGSRRHRDRSFRVFNFSEKIQSFFAESLHWSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SEY7</accession>
    <name>A0A423SEY7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative facilitated trehalose transporter Tret1-like isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_019409</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003559">
        <property type="protein sequence ID" value="ROT62741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SEY7"/>
    <dbReference type="STRING" id="6689.A0A423SEY7"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000218">
        <property type="entry name" value="facilitated trehalose transporter Tret1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050549">
        <property type="entry name" value="MFS_Trehalose_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48021:SF1">
        <property type="entry name" value="GH07001P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="438"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="93"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT62741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="543" mass="58235" checksum="0A5AE3F92FA127BB" modified="2019-05-08" version="1">MGKYNLQMRSSNSTEEPVLTATVKSIENDAVAGQDTCKNEPNGHCHASNLQMASLAGLTTEKDVDVLRSSDGGQNAKSGQEEDQKQEETRPRIISQVAATLVMAFIHVGVGAVYGYSGVTLPELTDPDTQDLFLGPYEVSLLASLSDLGGAFGSVVGGVLLMRLGQRTTALLGLPISAACWLAMAFAHSPTLLLSMWFVVGFVTGFLSPAASMYVLEVSHKNIRGLLFGIVTTARRFGIIFVFGIGGLRVGWRAIGFASSALVAVPLVGLLFMPSSPRWLVTRGRLEEAKDSLSFFRGKSYDVSSELASIVEQVERSQRRKSGFKDQLRMMMEPSTRRALALMGFLSLLSPFSGIVVVIGYAVPILQITKADIDAYMSALLTAVVFAAGTVIHICIVDRVGRKPLLVVSFLFSTLCMATLGGYFYAQTTEIDVSAYGWAPVASMVAFLFSMGVGQPVINILQGELLPTSVRATGISVILIFMYLGSFASAFTYPMITSAMRAFWIYSGVCITIVIVGAVCLPETRGRALEEITKAAPADNVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGG2</accession>
    <name>A0A423SGG2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mesoderm induction early response protein 2 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003464">
        <property type="protein sequence ID" value="ROT63265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGG2"/>
    <dbReference type="OrthoDB" id="5982258at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="642" mass="66928" checksum="DCDA17CC7435D164" modified="2019-05-08" version="1">MSSLRRSSSPSSPCGLLPRHSSSSLISLPPSSLPVAFSLATAPAPSSPSPQLQLPHLPVAFSLATAPAPSSPSRSLAPAPSSPSFSSPQLQLPHLLWPSPSSLISLGSSSLISLTAPAPHLPPQLQLPHLPVAFSLATAPAPSSPSPQLQLPHLPRHSSSSLISLWPSPSPQLQLPHLPRHSSSSLISLAQLLISAPAPSSPSPSSSSLISLPAPAPSSPSPQLQLPHLPVAFSLTTAPAPSSPCGLLSLPRLSSSSSPCGLLPRHSSSSLISLISLACSSSLISLLLPHHSSSSLISLATAPAPSSPSPQLQLPHLPRQAQLPSSPCWLPPSPSPQLQPPSSPSPQLQLPHLPLQLPHLPVAFSLATAPAPSSPCGLLPHHSSSSLISLTTAPAPSSPCGLHSSSSLISLTTAPAPSSPYSAVACSSAASSCSVSAVFLGQKRRPCPPLRPVRCLHVAAPPAHGARGLSIMPRVWIGVAAASCLLHYIGSASVEGTLKLERGNLTCINIFASETKKRQRVGHSAHGGTVHLLKYSAMFEYDVQCHVHTFCAALITLTGVCVNWRECRHHGQTVMAWKNGRALPTDIRQRVFENGTLVVMQTMRQSDGGRYTLPEPPTRTHRLQGRHRLRHRCVTAAAKVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGI4</accession>
    <name>A0A423SGI4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003452">
        <property type="protein sequence ID" value="ROT63302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGI4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="397" mass="46032" checksum="784D16894902A31F" modified="2019-05-08" version="1">MSKLQIKAFRTTIPGPPHTPQQLHNTHHTLTTTYTTTPHTLTPTYNKTHHTHHRTPQHPHPTTVQHTHHNPHTVHHNIQPYAHHHVHHNTHHTLTTIQPQPHDTSPRRTPHTHHILNNQRTPQHPHTSPHVHHNTHHTLTTRYTTTPTIPHHHVHPTPNKPSHRVHQTPPYTPRTTYTYTTTSKQPTTILLTNTYTHNTHHTSHHVTNNTHQPPHTTYTTGTPHAYSSTPPVHQNTTQYLPPRTPQPPTYPSPPTCTHKPQTLNHVHHNTHHTYHHVTTTPTIPTHQRTHTHYPHHHVHHNTHHTLNRHVHLNSNHITSRHRRTTNRHPPLPHTPAVTTTTIHPQPPVTTHAHTNPTTTYTNNNHHTLHTAVHQQTTYYPSPTYTHTPTYTSHKLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SGJ3</accession>
    <name>A0A423SGJ3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003454">
        <property type="protein sequence ID" value="ROT63294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SGJ3"/>
    <dbReference type="OrthoDB" id="6358219at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="453" mass="51622" checksum="8028B92D3B879811" modified="2019-05-08" version="1">MLAVAVANNHEGGVGGGCGRPADEEDLLLTRLRQMQSTLRECHWRLDRTDRWAESLFRKGEKEGAGKEDLAAPYLNGKEEPLECDPRVREGDVSVDKKPRRRGLVVREGVCKESIIESEVVEELVLRKEWEDDFDDYGNLLMTDAYLREAENTQNAAKEVKKNPTAKPRLERQNSLDVEVIPYTVPEPKSGPKEQCAEDVEEIGVHDMYLIEKKRLSLPRNFDENEIRFFSASPVSSECEYERITRSETPGSIWRKPRGGMRQANSLPNFQGCFDFGLEFALFKHLDSVEESLENLRLQFFTLKDAITHSTEEDSEFDLLLPDPWFITDQKEPKTQEPRSKRDPKHRDPTDKTVPEDPADEDKSEHLKPEAPTVPEHRDGNELPCSTEDKTESAEKTDNGDLRASSATQETTPSSLSLEDDLETTTPHITKEREKNQRTRTDARQHAEGTAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SHG5</accession>
    <name>A0A423SHG5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative sentrin-specific protease 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_018478</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003406">
        <property type="protein sequence ID" value="ROT63631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SHG5"/>
    <dbReference type="STRING" id="6689.A0A423SHG5"/>
    <dbReference type="OrthoDB" id="5065855at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="12"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT63631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="209" mass="24221" checksum="381E747A5AAC8836" modified="2019-05-08" version="1">MGDRVVLSYHDCLIMESDLRLLEGRNWLNDSLISFWFEHLQHEVFRGNSRLLFISPEVTQLIKMGDPNELPIFLDPLDAKYKEYIFLPVNDNSSVIAPGGSHWSLLIYSKYDSKWYHYDSQRGCNYRDARCLVQRINSYLDRDIPATLVDASCTQQDNSYDCGAFVMTYAHRAAEQALKGSAIGTCFVDRQETNRMRDLIKSLVYSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SL42</accession>
    <name>A0A423SL42_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_017215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003176">
        <property type="protein sequence ID" value="ROT64864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423SL42"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46844:SF1">
        <property type="entry name" value="SLR5058 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="4">
        <location>
            <begin position="363"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="964"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="135"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="976"/>
            <end position="985"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT64864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1460" mass="160262" checksum="4109C77F302F6470" modified="2019-05-08" version="1">MMGEEDDTASLSRLLDDAASREFSINGLHDDLASLSCGYASLDAHSGSHSEGRSGAHSRSDMGSSGESQEKSRTGSGRWSWQRSSPGSRRTSKSSIKSSDNLEEDVLDADDEDEKPPPALPPSLPPCDTCEDRSSTSSSCFTGTSSSVLSCTTCAAESDNRPEADPKSGDHPTEDAGHPVPAPSEHDQEQEQAPRIICKTPDPPDSKLIILSNGNTTPHRLSSTPEEVWSPGGEPPVPLVTSTPAPQGNNSNASTVEPKYVAPHHYVSSMRVASMRGAADMGGALVARVATFLRTQYKNLISSPLQLPWCPGFKMIVSEFETSLIQVPLAAHLKVPPGLLTVPSILQPLQLSFTESSMGDRPKRVLVEGDPGYGKSTLALKLAYDWATDPTGSYLSTYSLVFVLTLRDFRGGSVFSHLCKEVLPRHILSKEAMNTLWNHMKKIEDKVLFLLVGYDELIEEESGDMNELIDGQMFSNATVVLTSRPGSSKPLPPSMHRRLLIAGLAPDQTHRFISRYFDTINKPGSGNEVLSLISASKEKYGDLITCPIMCLALGVLYEDLGGKLPSRLTDMYMSLIKHMIRKNLIKRGEPMCYDVLPDRYNKLLSDFGKLALEALKQNTPYFTAQDLKTKCQHGGEIVELGILLRMQSMSKLSKKDFYTPAHKSFLEFLAAFYLSGLIHDTSLLQTEIDSIAEKMDITHPILRQNSGLMILRYLVGLLGRNAHIVFNIVSQMGVPQRILFLLLKESGMYQMNVLEERATNMYQKLVVEVCKHVSGREHVVIQTNSAELEDWGRLLYSPDCMLEGVDVLLDFDGSSRDRHESFFTSMSFNESVKSVKLTCVVGGDFGESEVTRLVSYVRAVLTKRRLESFEIQVTSLEEATAEILSPVVDMICDTLPDLAQALNKLVVALELDAEQVVQLCQVLQNAPHVQVLHLPHLACGLDGLKAVAQIVENSPLVSLNLAGSLSSGTPVDERSTGTGASTPSPTREDAPAPLSFWSFTDAQGNTRSVFNSLPRSFYQSLPGRGRLHSLSAEKRNSDTTLLQKTSFPPPACNPIVHANGFHEIFAAFRNPASRVCHLNISKCTMGAEDLVCLGETVRFTKCLSSLRMEGLSRMAEIIPVLIALQENTTLQLLDLTSPHILLGDAALQVTLNALAKNKSLRFLVLNGWTIQVESERSLKELIRFLNATELQHLDLSNCRVIVTVHDGALARLSRQDDVIAALQESVPPLHNNTLAFLNLDHFEVTLNSKVVLRGPQLLFMLRHFPKLVDVSLASSLGADIIDDSTTHRLFSLLPGSFPFLRRLTLGGWVFSLDNCEKVMRAGGKQLRGSQLREVILTGVEVRESSGTPGMEHTLLQALTTNLHHLSILSLAGLKLTANQAAMFGKTIRDKLATTTLELETRGLGYTTVKALRQAVTEGGRYEFDFLGGPLGIYKLSKIDRREKLIGKWACISTLDRLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SN78</accession>
    <name>A0A423SN78_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sodium/myo-inositol cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_016363</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003060">
        <property type="protein sequence ID" value="ROT65660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SN78"/>
    <dbReference type="STRING" id="6689.A0A423SN78"/>
    <dbReference type="OrthoDB" id="6132759at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005412">
        <property type="term" value="F:D-glucose:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819:SF150">
        <property type="entry name" value="SODIUM_MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11819">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT65660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="680" mass="77428" checksum="BCBF2BB3BF478757" modified="2019-05-08" version="1">MNQRILKSMEASRTKEPRQRRRRGRHAESTCSCSMCRPNRGTVAGYFLAGRFMWWLPVGASLFASNIGSEHFIGLAGSGAAAGIGVGAFEFNALVLLQLLGWVFLPVFIASGVNTLPEYTKKRFGGRRIQTYLALLSLILYIFTKISVNLYSGAIFIQQATKINNLYLSIVFLLVMTAICTVVGGLAAVIYTDTLQFFIMIGGSFYVMIKGLYTVGGYSELQTKYLASIPEKLISNSTCGLPRVDSWRMLRDADTSVSDMPWPGFLLGQIPASIWYWCADQMMVQRVMAAKSLSHAKGGTIFAGYVKLLPLFIMVLPGMIARVLFPNEVGCVDPDECFKFCNSRVSCSNSAYPKLVLEYMPSGVRGVMLSVMLSALMSDLTSIFNSASTLFTMDMWSIYRPRAKQREQLLVGRIFIVFLVVISIIWIPVIEQTQGGQLYIYIQAIAAYLAPPIAAIYCMAIIWKRMNEQGAFWGLMSGFVVGMFRMSLDFYYGEPPCNEEDNRPFIVAKVHYMYFATILFWLTVFVAVTVSLLTKAPEKWRLIRTTYFTRYDRRERQDDQEMREWKQNELMEVGQQDQDEAEHIPHRDTPWYQRLYNCIFGFDDSEKAQEQAMAMNEHIAQLTTLHQEPWEKNLLNVMLVIIIITTVACYTYFSINPFTEEEVKEIQRKKLEELGYHDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SNS6</accession>
    <name>A0A423SNS6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="3">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_016242</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="3"/>
    <dbReference type="EMBL" id="QCYY01003037">
        <property type="protein sequence ID" value="ROT65794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SNS6"/>
    <dbReference type="STRING" id="6689.A0A423SNS6"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000044">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000013">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 11" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="12">
        <location>
            <begin position="198"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="225"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT65794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="502" mass="55398" checksum="76F6CC9595B15775" modified="2019-05-08" version="1">MNGSVGERVAILDAGAQYGKVIDRRVRELNVESDILPLDTPAYTLKEKGYRAIIISGGPSSVYAEDAPRYDSDIFKINVPVLGICYGMQLLNKEFGGTVLRKAAREDGQYTIEVDNYCHIFKYMGVKQNVLLTHGDSIDKVADGFKVVATSGNLIAAIANDKLRLYGVQFHPEVDLTEQGVTMMRNFLYEIGGLSGTYTLQSRELQCINYIKEVVGTNKVLMLVSGGVDSTVCAALLHKALAEEQVIAVHIDNGFMRKNESLQVEQSLRKLGLKLRVINARHQFYDGTTSIPVDSSDPMGRKRVTNLLCMTLSPEEKRKIIGDTFIKVANEVIAEMNLRADEVMLGQGTLRPDLIESASSMVSGNAQNIKTHHNDTDLVRVLRSEGRVVEPLKDFHKDETTPRLCSLKPLSPHINLAPRSQTRYLSLIAHMDCDTFQPPAYSFQESLSTFNSLAPVTYCLSYNHLHSGSAGFSHTSSSARCSHFSFSHSDLTCGLPLACSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQC1</accession>
    <name>A0A423SQC1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002936">
        <property type="protein sequence ID" value="ROT66416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQC1"/>
    <dbReference type="OrthoDB" id="6377529at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="517"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="742" mass="77924" checksum="58316FB320131187" modified="2019-05-08" version="1">MTVPGGAQTEEPTGAATGEPIATATEEPTGEATGEPQRRRLGSPKCVNSGAQSDGDWGAHKWRQTGEPKVTATGEPTSASTGETQSPQGDWGAQRQTATGEPTVEAASTALRDGDCASTGSERPRLPPDKCQLPIAAATGEPTGAASNGASDEFQGPTPTPPSDKCSLLSDASENGPPNGSELPRGSQAEGAEAEDSALPVLAPVMAAARTESGDGQAEEPPAPPQEAGRSPLTPPESPPAKPPRVPEINEDIVLPPNAPQEIPDVHCAEEVEGPTDSPTHELEDQSKCSLGTKEAAPDTLKHTSVNEEAASSQSIDVTSSEAPLTLLPVSNLPVDESSNEPSTDSTPFPASSASGACKLEDPQLPEGGQRQPSAALVHEQRARRQREEKGAPAHSSHASSTVGGSLPPRPLIPRRTRRAHPVPAARSLQTLSSNPTKLSLAADRGAVSNEANYRKVSLPAKLNEPAREAPVPKPRKVSLNPFDSDEDNEEERRRRSAPREAPVPLPRKKISMNPFESDDDDDDDGNNNQGTADSSKETKPAGTNPFDEDEEEEEASIWKVNPATGELEFKPTLSSSPATNSRSSSQSSLTLQRLNDSIASLNAQLARTPHEPVSTNPFDEDEDDEFNEAALSRDSTRMSLSMGGPSPMQRDGARCSLPPSTRTRVGRKKRPAPLPPGQRPPIRARRPSSPAATTTVSRGAARRGCPSTTRQGSPPRAPSTSFLAPPGSSHPGSRPRHAARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQF1</accession>
    <name>A0A423SQF1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002936">
        <property type="protein sequence ID" value="ROT66411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQF1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="611"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="679" mass="74347" checksum="D7C05A0BD98CD68D" modified="2019-05-08" version="1">MRPHQRHDLLRSSQDTDVTESCPAPPPPSLPSFPPSYALPSRSQDTLGRRAVTTQTILAFHERPSPSFPPCVSVRTSRSACGSVRVRVEAVHMCARSLNSLATSFSSSISPFPSLPIPTPFLTPSFFFHHFLYSLPSSSTSLSFPLPPSFLLHLPLIPLPSPSPPPFPSLSISFSSLPPLPLPSPPPSHPFPLPSPPPSLPPSPPSPLPLHPYPSPPPPPIPSLSTSPSHPFPLHLPSRPFPLPLPLPPLPFPPPPPIPSLSTPPPNPSLSTSTSLPSHSTLPPLPSPLPPPTPSLSFYPSHPFPLHLPSYPFPLHLPLSSLPSPPPLPPLPPPSPSHRPPRRRIAHADLVTAALGFMGSYGLSTRRRTGVTGRRPPRSSFAATFARPRPWPCTDPPPPRRGLGGCVSLPPPPTCLAPSCIVSPGALVSPRVMVMLPTKLRQINGEIAGNCNSGDWESSVRVPRKRDPASVRLICILVICGRGTSTHPLPDTARGRARNNLDYDYHIKPTNNYRIKSTNNHIKPPTTTSDLPTTTTSNPPPTTTSNPSTTNIKPTINYHIKPTNNHIGPTNNYHIKPTNYQHKTHHQLPHKTYQQPHKTHQLPHQTHHQQPHQTTHQLPHQTSTCPQTHKQPPPPPHRTYQNLPPQPHHPKTRPPQRSQQRRRAERPGAFKPQRTRHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SRQ5</accession>
    <name>A0A423SRQ5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative pre-mRNA-splicing regulator WTAP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_015069</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fl(2)d family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002879">
        <property type="protein sequence ID" value="ROT66877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SRQ5"/>
    <dbReference type="STRING" id="6689.A0A423SRQ5"/>
    <dbReference type="OrthoDB" id="3366661at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033757">
        <property type="entry name" value="WTAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15217:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING REGULATOR WTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15217">
        <property type="entry name" value="WILMS' TUMOR 1-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17098">
        <property type="entry name" value="Wtap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="141"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT66877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="261" mass="28355" checksum="A0F6B3FD4E553244" modified="2019-05-08" version="1">MSGDGGEEDQVAKVEASAPISTITTTTATTTVTNNTSTTTTIQPTAEPVASSSSSASAVNAIVTPTITTAACAATPSATWTSPTVAVAAEDGAEEEEGEEEGSTADEPSSSPERVLITAEQLAVLTREEMVEKWVQQEKFIDSLQAKVDVLEREVEELRGVRENEERLKGQLAEIQRKEQYHIMRLSSKEHELQDMGAQIQELKSMSAGMSGLKHCLLDPAVNLLFERLKRDLDTARTKMEETQNELSAWKFTPDRCAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SUD3</accession>
    <name>A0A423SUD3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002755">
        <property type="protein sequence ID" value="ROT67826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SUD3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="430" mass="47452" checksum="2DB400708131096F" modified="2019-05-08" version="1">MTNVWRDFRPRSTRVLKLMRERACWSDTTLGKVRFEGNWGATGGQVFPIGEVISSAETFRVSLMGKKHWGKRKVLDSCLVEGFELCEGTMIYLHGEDSEFLECYVYLSELTSSAFRMSEFPESELLISEVPESDSEEFPESETSEEFPESETSEEFTKSETSEEFTKSETSEEFTKSETSEEFTKSETSEEFTKSETSDQNSRRPRLQKNSRSPTSRIPRRPRSPLRPRPGTSPREAAKPLSALVLAIPPFSSASSITHSGDEPLLPQPALLGDVALVVKLELSGHSVRGAPSAPPGDPSQRGESGREIERYKEAPEDLFKQDLLPAHDPVLLRGIPRGEDAPPATSMPLHGAPFPCDFVRVLPLAVGLRGEIDDPQQVLERLDIPKAPCRSPWPRPTSGWGAASAGPGEDCPHPAISSVSRGRIGFSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SVY4</accession>
    <name>A0A423SVY4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Cytochrome P450 2L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_013476</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Endoplasmic reticulum membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Microsome membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002676">
        <property type="protein sequence ID" value="ROT68379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SVY4"/>
    <dbReference type="STRING" id="6689.A0A423SVY4"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008395">
        <property type="term" value="F:steroid hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006805">
        <property type="term" value="P:xenobiotic metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000238">
        <property type="entry name" value="Cytochrome P450 2A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050182">
        <property type="entry name" value="Cytochrome_P450_fam2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300:SF403">
        <property type="entry name" value="CYTOCHROME P450 306A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24300">
        <property type="entry name" value="CYTOCHROME P450 508A4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="12 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT68379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="383" mass="43596" checksum="925320EF3BA43911" modified="2019-05-08" version="1">MVSPLVGYIPLSGKHMDEQFKDLQKQHGDIYLWRMGTQVMVFLHSYQLSKKPSAVVLFSTVRRRKCSDLWSLLLMVRNPVCNWKQRQHLHTNRRFSLRQLRDQGMGKSSLVSAIQKQARELVEALKGQASKPERIPRDLRVAVINIIWHMVANLIDGYLLDIEASKDDPDTIRTERDLCILILDLFFAGSETTVGTLAFMFFYLANHPEVQRKFQAEIDEVLPKGTLATLEDRSRMPFTEAVIHEVLRVSSLASLGIPHVAVRDTTLGGYLLPKGTIVWTAALTMHHDPRFWNDPEKFMPERWLDDQGKFATKKEGFLPFGVGKRVCVGESLVRMELFIISTAIFQSLSVSPPPGSKVDVSPVPGNPFIKTPRQEKVCFTIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZY3</accession>
    <name>A0A423SZY3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase M28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_012067</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002526">
        <property type="protein sequence ID" value="ROT69713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZY3"/>
    <dbReference type="OrthoDB" id="6341206at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF26">
        <property type="entry name" value="PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019169952" description="Peptidase M28 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="5">
        <location>
            <begin position="87"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT69713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="43063" checksum="B4BD24B96B0438CD" modified="2019-05-08" version="1">MGRGNLWKVVLLLGFAASSLAQKTQLQAHLEHLDGVRNPMAPSDEPRLEARRYIKDKFRELGLQVYGHTFRTVLKPLYDELTVSGENIIGVAAGAEGSPVMVVGADYDTPLQSLPLEDNGAGVAALLEVARHYMHETGAEGSFERLNTVIFVAFDLNVKAYGNNHPGKPGSYNFLHQFLWPYINETSNNFAGAIILDSISKFSTKSNSQYVVQEFSDAFPKASSAIANSHNTGDFLAMFTREDSRSIGLANKFTANYEKDRKAQMFRLQSMPVRDGLSFVGVLEMFNHQSHYPFWSFRPSEKLVPLPALLLTDTDVYRMSQDVCDRPCTPAAFLTRGREAFITKTIEAVTNTLLNLQTERLPVTSASGGLGVTTPLFLIACVTVISGIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T4Q2</accession>
    <name>A0A423T4Q2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vigilin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010189</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002290">
        <property type="protein sequence ID" value="ROT71489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T4Q2"/>
    <dbReference type="STRING" id="6689.A0A423T4Q2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="141"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="209"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="298"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="370"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="449" mass="49986" checksum="38E220F7DDFF7592" modified="2019-05-08" version="1">MATCELRSFDEHLRKEMSPRTSPSSPDMEDDVAFAAQMCKVKAIVKKARPAPPKRRTERPLPSVQPTADSVVSLPLYVTEQDRRRFLQQARKAADKYGVKVVRPHAGNLVAPFLVQGKREAARAFIERMEEDCVRGQTRSSDETASPDIAPEHYGQAIGKGGARLKYITEKYGVRVSVPKDRESPIAVSGQSESVRGAIREMEELVRQDLLKRRVALPVKVLPEDIGVVIGKGGCHAAQIQEEFGVRLRTQSHEHPQSPLIVEGPLDAAERAVASIQLRVAERRRLNEAYAEERRRREELRGTIPVRVEPGRVGMAIGKGAFRVRHVAQRHRVRIQLPERNKPDGQILVTGLKDDARAAVAELELMAKLKLRPEHVLVPLRIQSEEHVLVLGPEGCRAAWLGREFGVRVVRPSADGPLMLEGGVEAVARAEAHVEGVIAQRRLTTARRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T530</accession>
    <name>A0A423T530_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_010362</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002309">
        <property type="protein sequence ID" value="ROT71328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T530"/>
    <dbReference type="OrthoDB" id="6376286at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT71328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="353" mass="39702" checksum="60DE059641A4A05C" modified="2019-05-08" version="1" fragment="single">MASAERLWARTSGAELRRKVPRTSRPKPDRSDEQCCSSRPSRGGGKVSGKRMLLLVVSALACLAGVARASEPPVSPWQVLNPPLEAESDTLDLDPLQNTYPEEYESDSNVTAYEDEEEEEGYTHVPELPFKLPFKMDKKQIAVAMKLLKEAVKPILKSKALREAVAYLDDSLSSFNGDIETQLYLRLVLDSAQDIYEGKEAAQIHTILKEYITDMSDEETARTIDDVWDYVSPAMDEWFYAPVRKYLVAPVRDYVYYPFSNAINDFADRIGRFMNNGYDSSYVSVEYPQYQSRWSDTVNRFTNRISSWTTQARHSLEVAARVLDAQDAVYESRACGGSCGSTSLDETPASSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T6T5</accession>
    <name>A0A423T6T5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_009511</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002204">
        <property type="protein sequence ID" value="ROT72115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T6T5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT72115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="459" mass="49079" checksum="39F7490F4767B457" modified="2019-05-08" version="1">MRRKVLRAPSSSIFSLLSLRFTTSNNSLLSPFRPPPYSLLSPSFPTPHFLSSPSFQVLLISSSPSVPVPPYLLSPSISSSLSFSLRSHALHTLSPLLRFQSHISLSPSVSALHILSLSSSSSIFSSPSVSSSSILFLLSSVSSSPYSLSSPSFPAPPYFSLLLSSPPFPAPHTLSLFSLRFQLLHTPPLFSLRFQPSIFSLFSSFQLLHIPLSSPSVSSSSILSLFSLRFQLLISSSPSVSSSSIFSLLSSVSSSSILSLLSPIYLAPSYSLSSPSVSAPSNSPSSPSVSSSSILSLFSLRFQLSSSFFSVPAPPISPLYVSQRPSIILLSSSLVSSSSILFTASPSRFQLLQYSLSSPPFPSSSISSLFPFVLPSCSILLCCSPLVFQPPPIDSFSFSLRFPAPPVTLSLLSPVSGPSIFSLFSLRSAPPYLSLFLPPFPASMTLSPLFLHDSPKTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T7P8</accession>
    <name>A0A423T7P8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative CD81 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_009155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002154">
        <property type="protein sequence ID" value="ROT72465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T7P8"/>
    <dbReference type="STRING" id="6689.A0A423T7P8"/>
    <dbReference type="OrthoDB" id="10016273at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1450.10">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF551">
        <property type="entry name" value="RE08073P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00259">
        <property type="entry name" value="TMFOUR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT72465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="410" mass="44096" checksum="8FBAAD0C79A1884D" modified="2019-05-08" version="1">MMTSQAKHPPAPACASPPLSNLSSSSLLAFPFFRGLRLLRFLPLYFLSACPVFYSYPLSPPSAAPFSLPLSPASPSSSSSSSSFCPCPWSAPPQINTLCGTPSLSRVPSLPPPSLALSLSPSLTPFRLLSRLPSLPLCFPSLPSNFLPSTHGVITQTHVRPRSTQVLLWPLRPSAHTLDAHSPLFSPRQLLGGALLGTSLWMHLDGANMAPVTADLDGYNYVLYFLMAVGAFFALVLVLFAGQIAAGVWLKTNEERFTDLAKSSLAKSIQHDYGINKLKTQAFDVIQSELKCCGSEGPTDWAESRFNGADERGVLDIGIRGAIGAYKVPESCCNEKDKTLCEATRSLSIGAQITGSIYTEGCAKKMIQLIHSHSYEVLGVVAAIVLIEILAMIFSMVLCCAVRRIDHVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T8C3</accession>
    <name>A0A423T8C3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative extracellular matrix protein FRAS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_008931</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FRAS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002123">
        <property type="protein sequence ID" value="ROT72676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A423T8C3"/>
    <dbReference type="OrthoDB" id="430044at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00064">
        <property type="entry name" value="FU"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.200.20">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.10">
        <property type="entry name" value="Complement Module, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.220.10">
        <property type="entry name" value="Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039005">
        <property type="entry name" value="CSPG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051561">
        <property type="entry name" value="FRAS1_ECM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001007">
        <property type="entry name" value="VWF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45739:SF1">
        <property type="entry name" value="EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45739">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16184">
        <property type="entry name" value="Cadherin_3"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00093">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00237">
        <property type="entry name" value="Calx_beta"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00214">
        <property type="entry name" value="VWC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00215">
        <property type="entry name" value="VWC_out"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="CalX-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57603">
        <property type="entry name" value="FnI-like domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51854">
        <property type="entry name" value="CSPG"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01208">
        <property type="entry name" value="VWFC_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50184">
        <property type="entry name" value="VWFC_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="3857"/>
            <end position="3882"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="9">
        <location>
            <begin position="69"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="9">
        <location>
            <begin position="133"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="9">
        <location>
            <begin position="195"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="9">
        <location>
            <begin position="259"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="VWFC" evidence="9">
        <location>
            <begin position="324"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="1186"/>
            <end position="1273"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="1294"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="1440"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="1678"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="1802"/>
            <end position="1907"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="1928"/>
            <end position="2028"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="2049"/>
            <end position="2147"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="2169"/>
            <end position="2261"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="2281"/>
            <end position="2373"/>
        </location>
    </feature>
    <feature type="repeat" description="CSPG" evidence="6">
        <location>
            <begin position="2406"/>
            <end position="2502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3908"/>
            <end position="3928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="3908"/>
            <end position="3920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT72676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3957" mass="437280" checksum="A1C3D1B59D17E230" modified="2019-05-08" version="1">MQAKQASIAFGKTRPNGSSWRPEVCVECQCQGWVSVCQRQHCTDPECPPHHALYHNPKFCCPQCLPPALPCHAGGSLYQDGEVWSLGGCEQCRCVNGTVSCGRAPCAVTTCPEGQVALQDPEQCCPECVPVGMPCQEGSTLHDDGDFWSPVSCSQCQCRNGRVQCYVAHCPPLTCPANHTLEVAPGSCCPTCEGNPCIQKGMVYGSGEQWREGDCRECVCVAGRVQCHDMQCPDLQCQVDEKPYKEEGSCCPTCVKKQGWCLLESGVRQAPGSVWNISECEVCACRDAQVVCNEVRCEYSQCGPGEELVTRPGACCPECAINLNLCFHDTRLRQDGEVWSSGSCRVCSCNSGKVTCHTPACAPCPPGLAPVSSTSDDCCPECQPLTCPPNCMTCVPGSPNPTCTMCEEGHYLQDGTCISSCLEGWFQQGGVCLACHPSCAACNQATRFHCSKCHLESMLREGECVSDCGRGFYPEAESCFPCHSSCAECSGPEANHCQVCQSGAYLHAGTCVTSCPRGYYPRERVCEVCEEHCEKCGVGECLLCQDGFWLQDGRCLDQCLPGHYQGPHNTCLSCHSSCGTCDGPGILSCTSCPHYLLKSGSACVEMCPSGHYMGAEECLPCDSACSQCLGPGEHRCVECSNDKQVVVLVNGTAGECQDTCPENQKLMDHICISGSKGCKNWHVSEPESCLECEDGWLFQEQRCVKECSGGFFQQESGNVCLPCDPRCETCSGPSQKHCLSCHKKATLHERGESAECLTKCYRRTFLAEDNTCQTCHKSCEACAPDPGNSTLSLCLQCKGKRKIPQGQECVNVCHRGHFHHQVLDRCIKCHPSCATCKGEALNDCISCHDHAELTSEGTCEETQCPRGFYASGDGGCIPCQGDCDTCSRDGTICITCPPHLHLLYGKCVTKCPHMFYADDSAGGECQECHWTCEECLGPTESDCLSCAVNMFLEGNKCLPQCSPGHYAMGKTCMPCPAGCTACNSSSECQACHSPYLLQDGQCSTSCKSGTFANVFNNNCNKCGEHCMSCSLYECHECLPPYLLQDGQCVDKCSKDYFPSKDDGICYFNMKAPTLRILAPLVAEHNRPQIINGSIIYVQDADTPNNRLKIIIVEPPSNGVIFKVGGGKKMVMKKGHQFAVEDMHENRILYKHESNRPLYGEMSLRVTDGHFRSSVEMISVNVISKNQPEIVTNEPLIAVRGGSQAITSKILDIRDQDNSESVTVTVVDGPKNGHLSVRGEELVLFNLQELAEGVVMYTHDGSNVTSDMVLLQASDEHTVVNFLFQVYIVDHEKSIPVLVKNRGAKVQAGHRVQISPQLLQAADIDSDNGNLVYALLPMLQNPGHGKLILMIPLPPAPDGFYNDGWTQMDESHLIRPTTSFTQRDVNEGRVWYIHTDKQGQDSLISDQLLFSVADSSHPPNILSDQAFVIQVEPSNEPSEMSPTPGVQLDITVQEGQAVSITPQYLSFSGGKSPEHITYTITQPLGPYDGSLFNIDSPGLELRQFTQADINDMKIIYMPPLGDIGDEDKFFSFKFVVSDQMTGEPSGLPEQKFTIHVVPFQGSQLAFTHENPELIIQSRDSVLLEPQFFELKNLDQIEEIVFILLEAPQHGTITQEINGESFMFTEQDSFTKDEVLNSRIMYTHDGSESSYDFIVILALGHSSEASSRISITIRHEDDRQPTKSENASFSMTLREGESRVLSRLQLYFTDVHSPDEDLVYTLTSQPLYGALTILQPTGFSQMLNQTHKFTQADILYGLINYTSNVEIGISEVMDSLVFNVTDPNNNVLSNQVLKVRIQPVDNQEPRVTVGPAVEVLEGGSVVLPPSTVMATDADTPPTELRIIIDAPPIFGYITNTLAVPSLEPRSSPGNTSPMLEFTVGDVVAGRVAYVQSQHRHQEPTQDSLLFHVNDGINSSPTMRINITIQPVNDESPVILGEQVILEQGQTIVIRNQSLFISDTDTEPEDLIITIQQSPSHGSVHKKTSPYVSIKKSELLSRGQKFTFRNLLDELVLYSHDGSRDPEDVMEIMVSDGNHETGGIIEFIILRKTDEAPRLRLNHGLTLKAGEVSLISPSLLMAEDEDSEVAKIKYVVTRLPTSGNVELFEQEANAWRPLTVGSVFMQEDILNGNVRFSHQKDTQAGTDTLHFNLQDTEGNVMMDQALSITVLEDKVPPRITLNVGLSLMEDASAPITADLLSAMDAEMDPMELVFMLTSGPNHGQLELATAPGKAVTTWTQGALELGILRYQHQSADESPTDQFTFVVSDGYNNASQSFHINIIPVDDELPLLVLNHIKVQEGTRKTISQFEIEALDADTKDDLIIFEITRQPRHGSLQIKKGDKYIDTKTFSMRNLYSGDVSYLHDGSDASRDSFKIKVSDSTNSMYMKGRGEEATREPSTVHIEISSVDDGTPIITANTGLHFLQHEDGKAQNIITSHELHVEDEDTAPESLKFTVVAPPSHGVLRLTTHERPVMSFTQADIISGHLYYELTTYAQSVTSDHFTFEVTDSKPNTVTGNAFHIQWSWFVVAQREYNVTESDGEAKVLVKRTGNLKQPSVVTCATHTGSASGGKGRARGEDFTEITEPIEFGEGETEKYCTIPIHDDEEFEGPEVFTVKLTDPNYALIGKPKKSVVTIYDEEDKPKVEFETNTFAVDETEGFIFARLRRTGDLNVPASVMCLTKDGSAMGSEPNQLTSGTDFIHRNPDESSRVVFPPGVKMSTCNVKIIDDPEFEDNEDFMIYLKDPSDGVILGEIHEAIVRVKGANDDCKIKLTQTQYNVSESETAVSVTLDRTGIDLNYSSSIWCATKAFQPEEAQPSLDYIPHSEQVIFPSGVQTAVCNIKIIDDKVNPRLEGPEKFVVFISTAQNASIDASAAEAVVTIQDDEDAPSMQFTLPEIKVRENQTVVKIPIQRTGDLSRVSTVYCFTRQRSAKAGIDFIERPNTKDSMVTFPRGVSKVECEVGILDDLVFEKEEEFIVKLSHPESPSHLQPTVGENKITRVSILDWEDRPRVSFQRNDYTVAEPLAGELTSKFNIPIIRLGDVSQVTRVMVSTRDGSAASGTDYHPLHAEVEFPPGNTSIDMELTIVHNPSRQWHETFSLVLGPEEPVNAELGTITTAAVTILDHKSSGSSVLPAPPVVTSLLHYDNIEEHLGEPASPGYPLVCVTPCDPKYPESAKTAEMCAQAGLNASQMQYSWEVAIPADGDGLLMPFHSLTDDTLFASPNTKVLDSMFFARHFRVRCVAQPVRSDGVFGIPLRSKPISIGIHNGICQTPLVPGQPGGFQSQSFIATLSYINSTDEKHPNTVKIHVEIPHQDGMVPIVSTLPVHNLRYLLTEQLYRVHHTCSNMDLTAGFLAEAQDQHPINPRPYQSDSRLREKKSLELYQHLDLKTCMWTFSAWFSMSQLVDQCGGQVVSDFQVGSGGQSFLTVRVPLYISYVYAASPPGWASLDHRTELSVSFYYNTLLWHQGLHTQPTLTAKIQVTRISIDESGRLVIDLKTVAKFRGQFVLQHPNLEDHTSRLVAPEDLEIQFTLELMWTASTWDGPEQVWRATSEYNLKDYTGKYKLELIPCTVTPTQGYSDASPPACTPHPPTTFPLPIAIQQTHRPVPLIYTLNTDFQLFNSETMFLMDPKDVDNLQEVDYKGSYGPGQTIYGRVLWHPSQDLHSAYKLYIQRVFLCTGAEGYVPTYDPTGELYQEGPQYGCIQPSSKLRHRFLILDREHPYVEDGNLSIPKIEANFAEDLPEYETLHQFSGVDGFLLKTDALYEVNSGYQWYLQVLYTIGPSSSRSRRDAPLHTILSQFQSKENDHRRTLVKRTLTDLSEDYVKEEGEELPTPAFLRSLHTRNGTNMRGFQLDTGSKMDDGSIFLNVLYVIVVLVVLLGIIIAGLLLVKRHFRKSEKDKVIVVRSLKNEREQFRRKGEGKIQERPKTLPPHMTLNSESNLQTVKVKTLAITVRNNLEDEGTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T997</accession>
    <name>A0A423T997_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative RNA-binding protein Nova-1 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_008545</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002078">
        <property type="protein sequence ID" value="ROT73040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T997"/>
    <dbReference type="STRING" id="6689.A0A423T997"/>
    <dbReference type="OrthoDB" id="441329at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22435">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22436">
        <property type="entry name" value="KH-I_NOVA_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047275">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047276">
        <property type="entry name" value="KH-I_NOVA_rpt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="58"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="161"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT73040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="255" mass="27970" checksum="544D085890E0A6B3" modified="2019-05-08" version="1">MRTRHRLRQNMASSELTMEECVPSPGTPDSRKRPLDIDSDDAISKRSHYIPADMQSDGTYHLKILVPSVAAGAIIGKGGETIAQLQKDTNARVKMSKANDFYPGTTERVCLITGNVDAILTVLSFIMEKIKEKPDPNAKPAIDFDNKQTAEREKQISRSARSPQVKILVPNSTAGMIIGKGGTYIKQIKEESGAYVQISQKAKDQSLAERCITVISDGCHDGAESKGSLSAYNKRRVVAFILTRISRPYPSAMTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBB9</accession>
    <name>A0A423TBB9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL52</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">39S ribosomal protein L52, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_007793</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001995">
        <property type="protein sequence ID" value="ROT73745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBB9"/>
    <dbReference type="STRING" id="6689.A0A423TBB9"/>
    <dbReference type="OrthoDB" id="10249237at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034596">
        <property type="entry name" value="Ribosomal_mL52"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34090">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34090:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18699">
        <property type="entry name" value="MRPL52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT73745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="125" mass="14398" checksum="1F3F340C771A29CA" modified="2019-05-08" version="1">MAQHMIRNIFSISGRVSSLSARCISTTPIVNGKFQKKFDTSMGAWGPLVDGPDYTFLDGRPTPLRSGQRRRAKQQKEVSEKVLQLMKETNFAIERHQRLLHEEKEKKNQILNEKLKPKGHKLLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBT0</accession>
    <name>A0A423TBT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001972">
        <property type="protein sequence ID" value="ROT73896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBT0"/>
    <dbReference type="OrthoDB" id="6373456at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="110" mass="12590" checksum="60885D548EB4E6B9" modified="2019-05-08" version="1">MAFSCKVPSKKMIENIFQSHLNTKIRISKGVLPFLHLRFVLFLKELASSSDLEAFKQRKCFVSEKEIAKRAPPLLKKYCDVKRTRAAPQPQPDETSDSHATTDSEFVYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TFF7</accession>
    <name>A0A423TFF7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001805">
        <property type="protein sequence ID" value="ROT75176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TFF7"/>
    <dbReference type="OrthoDB" id="6348333at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38062" checksum="4CA6A92EF8199DDB" modified="2019-05-08" version="1">MSLFLGERTSSVAALEVEPLAIVDNLRYISFGLGPSENKSVLLCAYTLDEGQAVSGVLWEILKEEVAAGTFEWKPNAPATATGLLKDKVNLERDDSDLELTALTYDLSANYSCTVTADDGTTASAKDEILIIDTTSNHIYEEFSPTEANCSIRVSVRYFPVFPAPTVAAGLYSESLGEYVKEVDPWIAIRHPNGSVGYSFQDYDIKVDAGATDDTNFRCELGVRKANGTVIGLSKMTSHFYFKHSCKVLPVGENQTVSYNTDGRTCYGEPYAPGTTEARVACAEGFVSSGNVTSVTLVCESVNATVHRWIPGDEGLLPEDLLCEPTPADGAAMRVASCYALLTATLLLCLHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TJN3</accession>
    <name>A0A423TJN3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isocitrate dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="2">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Isocitric dehydrogenase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NAD(+)-specific ICDH subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_004732</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001623">
        <property type="protein sequence ID" value="ROT76668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TJN3"/>
    <dbReference type="STRING" id="6689.A0A423TJN3"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT76668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="197" mass="21499" checksum="0A41EBCD63DA7E61" modified="2019-05-08" version="1">MTPVGKGHRSLNLAIRKEFSLYANVRPCRSMEGYETLYKDVDVVTIRENTEGEYSGIEHEIVDGVVQSIKLITEPASRRVAEYAFQYARNNGRSKVTAVHKANIMRMSDGLFLRCCREAAERIQTSDLCAGLVGGLGLTPSGNIGEGGAVFESVHGTAPDIAGQDKANPTALLLSAVMMLRFMELHNHAAVIEKALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TL50</accession>
    <name>A0A423TL50_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_004210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001562">
        <property type="protein sequence ID" value="ROT77181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TL50"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026195">
        <property type="entry name" value="PSGL-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17384:SF7">
        <property type="entry name" value="P-SELECTIN GLYCOPROTEIN LIGAND 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17384">
        <property type="entry name" value="P-SELECTIN GLYCOPROTEIN LIGAND-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT77181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="218" mass="24738" checksum="E4AD09658F939739" modified="2019-05-08" version="1">MEMVNVSPIAMEMVNVSPIAMEMVNVSPMAMEMVNVRPMAMEMVNVRPMAMEMVNVSPMAMEMVNVSPMAMEMVNERPMAMEMVNVRPIAMEMVNVSPMTMEMVNVSPMAMEMVNERPMAMEMVNVRPIAMEMVNVSPMAMEMVNVSPMAMEMVNVRPMAMEMVNVSPIAMEMVNVRPMAMERVNVSPIAMEMVNVSPMAMEMLMCVLWQWRWLMCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLR7</accession>
    <name>A0A423TLR7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chitin-binding type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001532">
        <property type="protein sequence ID" value="ROT77384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLR7"/>
    <dbReference type="STRING" id="6689.A0A423TLR7"/>
    <dbReference type="OrthoDB" id="6364363at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.140.10">
        <property type="entry name" value="Chitin binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002557">
        <property type="entry name" value="Chitin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036508">
        <property type="entry name" value="Chitin-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052976">
        <property type="entry name" value="Scoloptoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933">
        <property type="entry name" value="FI18007P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22933:SF42">
        <property type="entry name" value="FI18455P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01607">
        <property type="entry name" value="CBM_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00494">
        <property type="entry name" value="ChtBD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57625">
        <property type="entry name" value="Invertebrate chitin-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50940">
        <property type="entry name" value="CHIT_BIND_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chitin-binding type-2" evidence="2">
        <location>
            <begin position="112"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="401" mass="40973" checksum="BD6661A4D28FDF8C" modified="2019-05-08" version="1">MATNGVNGNGYTNGANGNGYANGVNGNGVYRNGNGNGVYTNGNGRNGNGNGANGNGVYTNGNGVNGGYQNGNGVTVYANGVVDPFRALADAIGGGGVPGVDYPILAFVPATGFSCNGQLPGYYADTAPEAGCQVFHICQAGGRIDSFLCPNGTVFNQQYFVCDWWYNFDCSTAEQFYGLNAEIGNINGNGYTNGNGYTNGNGNGYSNGNGNGNGNGYTNGNGNGNGYTNGNGMVTEMDTPTVMVTEMVHQRQRNGNGYTNGNGNGNGYTNGNGNGNGYTNGNGNGVINGNGNGNRNGYTNGNGNGNGYTNGNSYRYTNGNSNGNGNGYTNGNGYTNGNGGVGPADIHRRLGNVTEPRQLMSAQSGDGFVDSGVATEMGVTHRAPDALARPPLRKMKCTSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLW1</accession>
    <name>A0A423TLW1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Interferon-related developmental regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_003937</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IFRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001527">
        <property type="protein sequence ID" value="ROT77412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLW1"/>
    <dbReference type="STRING" id="6689.A0A423TLW1"/>
    <dbReference type="OrthoDB" id="18978at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039777">
        <property type="entry name" value="IFRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007701">
        <property type="entry name" value="Interferon-rel_develop_reg_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354:SF1">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05004">
        <property type="entry name" value="IFRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Interferon-related developmental regulator N-terminal" evidence="3">
        <location>
            <begin position="34"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT77412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="321" mass="34680" checksum="8970E9B0D9FA0D36" modified="2019-05-08" version="1">MRTPQQDSHSLINQITLAQSAGEALPVADDDTASITSDKTDSTAQITDGEEGLSEMETYEQKVREAMDLALEKSVQTRTNALTALTTAFQKRVMTQFLLDNYQTITDLVERSLRKGRGPEQVAAARLATTLVVSLSPVAEAEKVFKTLNPILTVLVTDPSAAVAARQDGALAMALSAFLACHDLADVTAAMNTLHTLFAGSLPKGNGELPNHPPAVSAMHTAALNGFCLLLCLLSPTTIYTMANKLVKEMFDLLGSSDLDLRIQAGEAVALIYETLEYMMRDYSWNREADLCSVLKELATDSPGSEQKRTGSNREHLSGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TM80</accession>
    <name>A0A423TM80_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">G-protein coupled receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_003807</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001511">
        <property type="protein sequence ID" value="ROT77567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TM80"/>
    <dbReference type="STRING" id="6689.A0A423TM80"/>
    <dbReference type="OrthoDB" id="6432667at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13952">
        <property type="entry name" value="7tm_classB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057244">
        <property type="entry name" value="GAIN_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046338">
        <property type="entry name" value="GAIN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017981">
        <property type="entry name" value="GPCR_2-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000832">
        <property type="entry name" value="GPCR_2_secretin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000203">
        <property type="entry name" value="GPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011">
        <property type="entry name" value="ADHESION G-PROTEIN COUPLED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12011:SF347">
        <property type="entry name" value="FI21270P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00002">
        <property type="entry name" value="7tm_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01825">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00303">
        <property type="entry name" value="GPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50261">
        <property type="entry name" value="G_PROTEIN_RECEP_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50221">
        <property type="entry name" value="GAIN_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="638"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="672"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="705"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="744"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="783"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="826"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="859"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="GAIN-B" evidence="8">
        <location>
            <begin position="435"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 2 profile 2" evidence="9">
        <location>
            <begin position="638"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="901"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT77567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="929" mass="104953" checksum="9F69864F7F8C7525" modified="2019-05-08" version="1">MRLKAKVSTDPSVPTSSTTTEPPITYPPHVSIQELLYETTTDMHAGSLEDFMVGANGEDEDKFEQTDGPFGFGYAVRVKADNQECLVKQNYESAGDCTKDPNICSKGFSISIWEKADFSYDIFWTINNLQNEPKRYVLSTGGDEQGHPGIAIYHQGISLVAIVSTGDEYWKLEVYGPFHNSTWNNIGILWSRPQGENGGLEMHVNHRRVGTVYKGMASTRKSPLNPSELMIGCHKDSDNQLYRGYNDAEFDELALWKRSLLDNETMFFLGGYEGEMSFIDPEEYQVMLEKTDLKDSSQLVAAFKVLSLMDVASRPENATEEEAMNNTLRLQNVMASLTNPENIKQDLGVDDWVQFLDIIHATSNLLDDDSEDTWRVMEAKGKAGATEVARDFEGFYLDLLDKVSLEGKTELDYTKTSENIAARCEKTRIRDFVAAPTYVSPDYNQMKSLYSDWDRPTDKIYVPTNMFTDERCLEREVSILTVLYDTYDDVAPNRVSARYGLRDHPPSMPNYLDSRVLSVRVRGVPELDSQGRVIPSSPQCAPDPDALWRNPLKIILEHKVKEKALRRMLFHDEEPTTKINFRHCVRWNDRYQMWDGDGCRVEETTTTYTRCSCRGFGSFAIMVEEIEPIVAPEIPEGLIMVIKIGYIFSMICLLLYVLIVGLSGDLKDQHHLVGLNMAGCLFLGDLMMLLMYFLPIHEGRHNCTIVGSLIHGFFLAAGGWMAMMGHTAFKTITAGVIGGKLRAYFFLSWGITISSIGVTYISFLRHLGTDPRCFISWTNEVKGVFFVPQLGFCMAAVFFVCIVFFNLHTSHLRTGSILADYRSFSIGSSVLALYFCTTWAIGCAALIRWEDDMPNLYPIFEILNSFTGLVLLLCIGFGSRRFRMSISGQYKKKRQMLNDYRNKNDDTQPLGSPEDQPRPISAASTVIAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMB9</accession>
    <name>A0A423TMB9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_003751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001507">
        <property type="protein sequence ID" value="ROT77597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMB9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT77597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="58121" checksum="31F72322D453BBD7" modified="2019-05-08" version="1">MITKKYIIPRGNLRNNHRETYINTPSPILPHLPSRCTAHYASLFPPVLPATPFPFPSPLPAPFEMPPPFSSTPPPPSLVLLQDLDSRPRSASFFSPILIFSSFPIVFFFLSMQCPVISLSQRQTLRLPPTLVMFLSTTSPTLPPLLFFKVLLLYQYLISLLFPNTFRPLSPLLFSIFPLSPCTLLDAPPPPSPTLSSLAASSMSLLFSTFSSTPCNLFDAPPLLQHCPTPPCSSSSGPPTILPFFPYRYPHLPYCHRPFPYHWPHILFPLPYLLSSFLHPNLTYPSPSLNPPSITLPLSLHPSTFPLSPHPFLPLTPTPAPSLLSPPARLPSLHPSLTSLSPTPSPNPTFLLSPPSTFPSLPTSSHPLPPHPLPLPPPPPPLPSPPHPPPTSRTFPSLPPPPQLSPFSLPTSPPQVPEMRQGQGDRPTHQINLHKARMSLFLYFPRFFLSPLLSSFSLLLSSFLYFPRFFVLLFSLLLFSLLPSSFSISFSFVPSLFLPSLLSSFLYFPRFFVLLFSLLPLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMR2</accession>
    <name>A0A423TMR2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001483">
        <property type="protein sequence ID" value="ROT77761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMR2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="413" mass="44548" checksum="B81DE0CAE4EABBDE" modified="2019-05-08" version="1">MSPAPLLTACLRPGAVTESTREVQSLIPPVVFFSSITNILDHGRLAWQTRPLLCPRSSAPNLPNLVCRRPSLRLQSSKPFFLFHLLFLSLLYLLFHPLPSSSSLVVPSPFPPLLVVPSPFPPLLVVLSSCSIPSLLFLFVPSPFPPLLVVPSPFPPLLVVPSPFPPLLVVPSPFPPLLLSISFPPLLVSISLPSSSICSISLPSSSSCSIPLPSSSICSISLPSSSICSISLPSSLYLSIPLPPSSICRRPPPPQQASSLFSIFLPSSPFWCPISSPSPFSSSISLPPFLSSFFSRRPSLLPFPAVPPPFPPPFQAVPPPFPPPLFSRPAALPYPPFSRPPPLPPPLSAVPPPFPPPFSAVRRPSLPPFQPSLRPSHLPFQPSRRPSLPPFQPSLRPSLLPFQPSRRPFPPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTM2</accession>
    <name>A0A423TTM2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001499</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001189">
        <property type="protein sequence ID" value="ROT79772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTM2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT79772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="18149" checksum="F21AA6DC2AE6474B" modified="2019-05-08" version="1">MGKERRHPFSNRNPMIFAMKHELHNNFSTSTYDSPLPPPLSLLLPHPVNIYRSHNTKAERGKRGRRKNNLNCTLALSATVFHGRVVMPEHYVCANFYKAKIEELVYRECRAALITTPTLDTPTNEHRPSPHSTPNDPARCCIRETTSCNRQKEDCSGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TTZ4</accession>
    <name>A0A423TTZ4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_001390</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001177">
        <property type="protein sequence ID" value="ROT79912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TTZ4"/>
    <dbReference type="STRING" id="6689.A0A423TTZ4"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000140">
        <property type="entry name" value="Coatomer subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="8 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6 14" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="TPR" evidence="15">
        <location>
            <begin position="206"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT79912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="296" mass="33560" checksum="347AF67226818C97" modified="2019-05-08" version="1">MANQEVDELFEVKNSFYIGNYQHCINEAQKLQVSSPELRQERDIFLYRALIGQRKFGVVQSEIKASAPPPLQALKLLAQYFQFPSNRVTIVNELESQLSGNVDLSNTALLIVAATIYCHEDNYEGALRALSQSDALECRALMVQTYLKMERLDAARKELKTLQEKDDDATLTQMAQAWTHIATGGEKLQDAYYIYQELLDKNVSTALLLNGQAICFLGQAKYEEAESALQEALDKDPSNPDTLINLMVLAHHTGKPQEVANRYLVQLRDEHKGHKFVEDITTKEEDFNRLVKQYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TVA5</accession>
    <name>A0A423TVA5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Proclotting enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_000960</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001132">
        <property type="protein sequence ID" value="ROT80312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TVA5"/>
    <dbReference type="OrthoDB" id="6357057at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000028">
        <property type="entry name" value="Serine protease easter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258:SF143">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24258">
        <property type="entry name" value="SERINE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019408153" evidence="8">
        <location>
            <begin position="22"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="10">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="486"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="362"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT80312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="819" mass="86246" checksum="4346D0F6DE788E45" modified="2019-05-08" version="1">MRVCFSVTFIAITCLATQVHGQGGIVALGTEEGGDGGEGGSAVPPSVCQDLNPSCPGWGERGECQSNPAYMLANCPVTCDSCLPRSDSECVNRDDEQSCDLEAILGRCKTNPSYALRFCAGSCRDFIDVCASPGVQDIRSCSGPQSITEPDFECGLVPTVARRGLPSASEGRDRRGDLRFELLRSPRKKRDKKWIRKLKRPPRKKARPPPLPLRQADIDEGVALNITQELNITIEINATQVEGNATQGIEGNCGNIQRTTSTVAGENLIDWTAVSIAVPLGLISAGGYLKLVSQLQGLARGHTGRPLDPMAFELVEAISFCRYGSAETPPPLAANIFLGGGPAELDTPPTWPGMSYPGLFLHDNTSSPGRQPAVGTPAGAVPPVSLPDGAEPPVAPPSGAVPPVDAPEGARQPVAFPGAALQPGDIPAGGLPLEGEGSALPDSLGAFPPLGTAEGAGPPLGAAGPMQPVDGAEGASPATDAGPSTVAVGEGDGDGAEGPIPVTEANDRNRFFCGGALVTPRHVLTAAHCVATRRPDVIRLGERDFTRSTESQAFDYPVQRITLHPDYNFLSNYFDIAVIELRDKVEFNSAVQPYCLPASPEALDGLTCTVSGWGSRPNEFASTLLVSLDVEVKSLAECNDLYSAAEDVFRVKYPQGLDATLLCAGGGSGRDGDSGGPLLLDVDGLETEVGVVSAGLGCGDPRFPGIYTRVDAFLDWLDRTVYGVCARAESLDYETRTAAEIWVWIKAVEFKMGLGKAWARNALNWWAGREKADIPSNSQRTSRPEALQGPLQLSGLGPPVALQTYGGFYIITFDLHIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW44</accession>
    <name>A0A423TW44_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_000595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001094">
        <property type="protein sequence ID" value="ROT80657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW44"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="375" mass="41092" checksum="738AD47233889F53" modified="2019-05-08" version="1">MHEGLHFLGRNVVTRIRSGINPGPMRRPGSHHHYKTATRKFQNSMAHPMPFQTLSPPLLLYFSLLPLPPLDSLVPSPLIFLFSPLPPLPSLPFPLLCPLSSIFFLFPSSCTSLLPFTLSPLIPPSCTFSPLPPLYYFTPLLLCLLSSPFTLSPFLPLAPPPSSYTFSPHPLLCLLHSFSSYAVSPIPLSPPLLWIPSPPVLFLSPVPPPIPLSSPLLYASCPPLPLPHHSSPSLSLLIPLSITLSLSLSHLPLSLLHCPRLSLFLSPISLPPYLPSPTALSPSHPPPSLTRLSPSLSLSIPPTLSLPSPSLSPFLLLPLSIHLSRPPPLPHLRIFLFLHTFHFHFDSGLDVTALSRLSPPNEPWFIHTSQVIYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TW55</accession>
    <name>A0A423TW55_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">kynurenine--oxoglutarate transaminase</fullName>
            <ecNumber evidence="2">2.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_000605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-kynurenine degradation; kynurenate from L-kynurenine: step 1/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.7" evidence="2"/>
    <dbReference type="EMBL" id="QCYY01001094">
        <property type="protein sequence ID" value="ROT80667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TW55"/>
    <dbReference type="STRING" id="6689.A0A423TW55"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="16"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT80667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="160" mass="17523" checksum="06D0B1A6E4C14A4E" modified="2019-05-08" version="1">MLTMVEFIQLALEVKPLNLGQGFPDFAAPDTVRKALAEACTDEKNVLLNQYTRGFGHPRLIAALSKLYSKLIGRELNPLSEVLVTAGAYEALFVTIMGLVNQGDEVIIIEPFFDCYVPQVKLAGGTPVFVPLRPRKPSGTMSSADWILDPAELEAAFIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZT0</accession>
    <name>A0A423TZT0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000901">
        <property type="protein sequence ID" value="ROT81963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZT0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="456" mass="49578" checksum="0D27A819F833651E" modified="2019-05-08" version="1">MHTTWRPHARQGVPQAARTSRTRAASPASGVFARRRSGVTALTLNRWRALFFLAHFFICFLLTNLFLISSLFISFLLISYLLISFLLISFLLNSSFLFLFLSLPPHLFLTSLSSFLPPFLSCSFLPFYFLLLISYFLNRSLPFFPSFRSLYFLPSSLFFGLSISPPPLNLPSLFLSPGFYSTSFLLLSLSLSFTLSSLPPPLLSPSFSIPSPSFPPLPSFNPPFSFPPFPRHPSPSLPSLLPSLSPSFPSLSIHPSSSLLLSPIPSPSFHLSFPPPSPSLSSPPLPPSLSHPSPLYQSTLLPPSPPPLSLSPSFPLYEPPLSPPLHPPPSPSFPLYQSPPPLFLHPSLSINPLPLSLSILPSLSIPTFRPAHAHARPVACERPGRPFVQRPSANTLHSGTSPLATVATSLPLKGRTCSGVTCSGRTCSGVTCTPALLRCKAFRQVRVGVGGTCNFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZX5</accession>
    <name>A0A423TZX5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_024846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000898">
        <property type="protein sequence ID" value="ROT81992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZX5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT81992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="105" mass="11462" checksum="3277CAE5C2980A89" modified="2019-05-08" version="1">MKVVAELVEHVGSGVAEQEAKNRPRCVLAMKVLAAVLIALLAFTQRVGGQFDGIIHNIAKSTLCENQYNGCEDSFERRTHAAAEVRDDDVHATGPAGKRRLKLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U430</accession>
    <name>A0A423U430_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein UBASH3A homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023348</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000678">
        <property type="protein sequence ID" value="ROT83478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U430"/>
    <dbReference type="STRING" id="6689.A0A423U430"/>
    <dbReference type="OrthoDB" id="414418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11791">
        <property type="entry name" value="SH3_UBASH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000032">
        <property type="entry name" value="Blast:Protein UBASH3A homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="79"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00083868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT83478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="513" mass="57283" checksum="B2A06EB0DD4FC898" modified="2019-05-08" version="1">MPGNIKERLTSPYLMFLTTVYLAQTGTTGEAATKALHLTLAYQFPPSHFSRLESLVDIVDPRAPAAWEVRLYSRDTRIVGNEVHKVLYSHVPREPDELELLIGDFVYVNGDGLGTSPDGWVEGTSWLTGSTGYLPINYIERTAESDAWTLHKAIPVIGNSGLEGLETATFPRRPPISLSLLNLLENSEGSRRSTEVLSESSSMDRLHSRQASLEANQSPLLPKYEALDALYAKVKKPKKDAPLYKFPIEGPRKIIVARHGERVDFTFGDWIRFCFDETGVYTRRDLNMPEKLPCRVGAPHSFYKDCPLTNIGLLQATLVGQALKNSSTEVHHVFCSPSLRCVQTCTNILKGLGIAERMPINIEPGLFEWLAWYQDGLPVWMTLDELIEAGFNINRNYDPLIRKEEVKDTHESCEQYYGRNAYVTQSIINTTQAQGGTILLVGHAATLDTCTRQLVGGAPRSAHEMTSIIKKVPYCSFSIVGQETSGAWSLLEPPFPPVTHSANMRYDWKVLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U9E6</accession>
    <name>A0A423U9E6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secernin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C69 family. Secernin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000310">
        <property type="protein sequence ID" value="ROT85330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U9E6"/>
    <dbReference type="STRING" id="6689.A0A423U9E6"/>
    <dbReference type="OrthoDB" id="5175656at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994:SF17">
        <property type="entry name" value="LD30995P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="SECERNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="142" mass="15611" checksum="6D29CC307A615040" modified="2019-05-08" version="1" fragment="single">MAVEVVTSLLQQYGQGGPCSDTDTDFVYHNSFLIADPQEAWILETAGKHWAAENVKSGYRNISNALSIGTKIDKMSEGLKELAQEKGWWDGSGDFNFSEAYGASQDAGQERKECGEKLLAKFSEGGEEKERVCQGFTCISKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UA94</accession>
    <name>A0A423UA94_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_009790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000224">
        <property type="protein sequence ID" value="ROT85632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UA94"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="479" mass="52613" checksum="A6F19E6B66E07CD7" modified="2019-05-08" version="1">MVNRTGTSESKITPSYQYKSHSCVVATCYVTPFNLYKSYVLMEVIPFPRLNSLFGYYIYLFISLTSLLSPSPSILLNLICLSLDLPLSLYLSPLPLYTNITYLLSLTYLLIYSLPSIYLFCLSLPPSSSSIILLSLSILSYFNLPNSLLPSPTSLIISSNLNIAVVCHPRSLSSLSPSLSQAPFLIPLLFLLFHLFFTCLLSLLAPYSLSSSSVHSLSFHSVLLNLITLSPSHLHSFLLSSLTPSLFSLSLVAHFTSLSCSITLLFFPPPPTLSYDSDPLSPIHYYCSFTSLLSLFSSRNPLSRSTFLSTTTLSSFSSRARNSYYFLLSLSIHSPSHLVHHTSTLALSLSTTTHHQSLACSKLLYFYYSVFSSPILSLSLSHTSASSINLHSSHSRSLFSSLVHDSSFTTVSSFTNHVSASSDSSLSTLLSMIVLLFSPHPNTSLLPSSSFYLLLLSCQISSALHPLSSIFPFSNDNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UAI5</accession>
    <name>A0A423UAI5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007824</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000200">
        <property type="protein sequence ID" value="ROT85727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="652"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="783"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1318"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="790"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="823"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="859"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="894"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="948"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="976"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1106"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1207"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1220"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1321"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1427"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1495"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1528"/>
            <end position="1540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT85727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1546" mass="164044" checksum="EB0B07B2A6A694AA" modified="2019-05-08" version="1">MSSHLLPLHLRMRPSTSTPCLLPLHLHPSTLLPLHLHPRSQDTLLPPPPPQDVITPPPHPQDVLPHPHPCPPPPPPPQDVITPSSPPPPPPGCHHTLLPLHLHPTPRMSSHPPADVIKPPQEVITPPAPPLPGCHPPAPPPPPPGGHQHPPAPPIPPQDVITPSTSSTPQDVITPSSSTSTPRMSSHLLLPPPPPQDVITPSCPSTPRMSSHLLPLHSTPPQDVITPSCSTSTLTHTPGCHHTPYPHLHPPPGCHHLLPLHLPPGGHHTLLPTPPPGCHHTSCPSPPPPPQDASNTSCPSTSTPRMSSRPPPPSTPPPGWSSHPPSPPPPPPGCHHTPPALHLHPTPGCHHTSCPSTSTPGCHHTLLPLHLHPQDVITPSCPSTSTSPPITPPPLHSTPRMSTSTPRMSSHPPTLHLHPQDVITPSPLHLHPQDVITPSYPSTSTPRMSSPPPPPPLHSPRMSSHLLPSTSTQDVITPSSLHLHPQDVITPPLHLHPRMSSHPPAPPPPPPGCHHTLLPSTSTPRMSSHPPAPPPPPQDVITPSYPSSTPRMSSPLLPPPLHPQDVITPSYPSTSTPGCHHTLLPLHLHPRMSSHLLPLHSTPGCHHTLLPLTSTPRRHPPPSTCPSSTLQPSTFHPGCHHTLHLHLPPGCHHTLLPPPPPPRMSSPSLPPPPPRMSSLPSTPPPPGCHHTLLTSTSPQDVTHPLPSTSTPRSPSHLLLHLHLHPQDVIHLLPPSTPPPGCITPPTHSSTPRIITNLCPSTSPQDSTTPPAHLHLHSQMSYTFPHLHPDINPPAPPPPPQDVITPPPPPPPPPQESITPLLPSTSPQEVITPSCPSTSPPRMFITPPTLHPQEVITLLPSPSTSTSRMSYTSSLPSTSTPRMSSHLLPSTSPHHTPPPPGCHHTPYPPSTPGCHHTLLPLHLHQGGHSHPPATSTLLPPPPGCHHTLLPSTSTSPQDVITPSCPSTSTPGVIHPPALHPPPQDVITPSCPPPPPPGCPSHLLPLHLHPQDVITPSCPSTSTSTPRMSSHPPSTSTQDVITSCPSTSTPRMSSHPPAPPPPPQDVHPLTPLPSTSTPRMFITLLPHPQDVITPPSTPPQDLHPQDVITPSSCPSTSIPRMSSHPPAPPPHPQDVITPNLLPSTSHHPPPPPPPRMSSHPPAPPPPPPGCHHTLLHPLHPQDVITPSCPSTSTPGCHHHPPPPPPITPSCPSTSTPGCHHTPSPPPPPPGCHHTPLSPPPPPPGCHHTLLPLHLHPQGSIRTLLLHLHLHPQDVITPSYPSTSTPRMALHPQDVITPPPSTSTPRMSSHLLPLHLHPRMSSPSYPPPPPPGCHHPPTSTSRMFITPSYPSTPPPGCHHTLPLHLHPRMSFHPLSTPPPAPTPRTLHLHPQDVSHLPPPPPGCHHTPYPSTSSPGCHHTLLPSTSTPRMSSHPLPLHPSTSTPPPGCHHTPPTSHLHLHPRMSSHLLPPPPPPPGCHHTLHPSTSTQDVHPSPPPTSTPGCHHTLLPPLHPTPQDVINSSPSTSPTPPRMSSPLLPLHLHSTPGVITPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423UBM5</accession>
    <name>A0A423UBM5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lectin B isoform 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_007818</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000002">
        <property type="protein sequence ID" value="ROT86097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423UBM5"/>
    <dbReference type="OrthoDB" id="6328824at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050111">
        <property type="entry name" value="C-type_lectin/snaclec_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018378">
        <property type="entry name" value="C-type_lectin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22803">
        <property type="entry name" value="MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00615">
        <property type="entry name" value="C_TYPE_LECTIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019199473" evidence="2">
        <location>
            <begin position="21"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="3">
        <location>
            <begin position="29"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT86097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="164" mass="18581" checksum="755409BB75CD2364" modified="2019-05-08" version="1">MRGIFPSIFYIFFLKVSVQGLCPEPFESVQDKCYYFELEVSRTWDNCRARCQSLGADLAILNTCEEFSLLVKHIHISQLEIPDNFSFFVGGTDRGDEGVWYWVDGSPVKMGVPLWGQTDFIAEPSGGTEQNCATLNKANRYYLHDGECDKNGYAICQIDPVPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRS4</accession>
    <name>A0A3R7LRS4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Supervillin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_021062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004298">
        <property type="protein sequence ID" value="ROT61194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRS4"/>
    <dbReference type="OrthoDB" id="28894at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051014">
        <property type="term" value="P:actin filament severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008154">
        <property type="term" value="P:actin polymerization or depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007122">
        <property type="entry name" value="Villin/Gelsolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977:SF45">
        <property type="entry name" value="SUPERVILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11977">
        <property type="entry name" value="VILLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00262">
        <property type="entry name" value="GEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="702" mass="77326" checksum="D9785D252829AFB9" modified="2019-04-10" version="1">MSEDDREGAWVHVVGDIHMNILPLLVAVIALVILSLAARLLLAALQKNGEDGWKSRLKSDGKDVNSNVTLRPKPAGGLRERPVSLMERMSALENSSQQWRGRVTQSDATKFTVAHKMASASTSCVPSVVSGVTPVLTVTPDQPTTPIGSPTVERKKRSPSQKVFKSKTGGNIPSLLGKSSPLSARKDFRRSISTPNDRDKKAEAVEGPSVAVPRADDEDFIAFFSKTSASETVQSPEDGVPSLGDADFDLISETASQLVVKRRSVRVTRRQATSRNPLKALAAREDIKSEYTEVKLGIGEKELKRMKVEELSKGSPLAVEALAGLASKENFSAVALKKVENNPVVREMAPYTSLMLLQVKGRRHAQTRLVKPAVSSVNQGDDFILITPTDVFHYKGEFANVIERAKASEIAQYIVQKKDMGIGSALRNVIELDENSPSGRKAKFWRLLGGDETSSGQLCGMPDEDELIEASLVAANKVYEVQEDSLVPIADSWGQMPKIEILQSEKVLVFDFGPELYIWAGKRACGDERKVGLALGRELWEEEYDYSECDINPITPMVPLSQAALKGIRPEWGLCAKLTENVETIVFKEKFIDWPDLAQQSRIKEVKKDMDRHVAPVCELQPCDARVMLEELPAEPDLVLEMSHLGRGVEYYDEEHTGFLPENLVSSPRSHVELPLDFWSSHILPNFSHNAPSTGDLCLDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LT64</accession>
    <name>A0A3R7LT64_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_019943</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003760">
        <property type="protein sequence ID" value="ROT62221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LT64"/>
    <dbReference type="OrthoDB" id="6376410at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT62221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="62747" checksum="9410F5827A08F479" modified="2019-04-10" version="1">MGRRNGGSRNNSPSRPSTSQEAASAPSVGRNSPSGQTLLPDSDDRGIERLPEISVMEELFQKISQLTLEVQNLRFQNSELEARISRPSTPVSVREAPPVEFVVQRDPIPQFKAEVSSAHPLKRNQEVESWLRSVENHTRPQTDAAFIKAAKASWITDYPRALVTHDLIRRVFLQGLPRWIREAVVVKEEAELCNLVETTQRVWSLRESEGPGVSSPTRSPFRPRFLQQPRSGVAATPSLASKEVLSTTDCDNEVLQKPAGRPMVSLMVNGFKTQCFVDTGFDAVGDFGGADDYILLPDVDLPPCSVVTQTPVGVDQSGSSTDCPEDVQLKDAELGDLLSEIDLGHLTLEQQQQLRQVLVKYVALFDAQANGMIERTNRVVKNALATLLEASPLEWDELLPYVRLAMNSAVHRSVGDQPLYLLTGHIGTYPVGNSNYEETDHEAAQSFAARLRRAREIAVETSVQAREGWARDYNRRTRKSTFAAEVGDLVLFKDLPRMAGAGRRGALGPRWFGPARICKKTGPVTRLTGSRRMILQLLSWLPFADLLTMVSLDWSPSLFLLEGLCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LU73</accession>
    <name>A0A3R7LU73_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cyclin A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_017624</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin AB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003251">
        <property type="protein sequence ID" value="ROT64441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LU73"/>
    <dbReference type="STRING" id="6689.A0A3R7LU73"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044772">
        <property type="term" value="P:mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000001">
        <property type="entry name" value="G2/mitotic-specific cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032447">
        <property type="entry name" value="Cyclin-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046965">
        <property type="entry name" value="Cyclin_A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048258">
        <property type="entry name" value="Cyclins_cyclin-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16500">
        <property type="entry name" value="Cyclin_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001771">
        <property type="entry name" value="Cyclin_A_B_D_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00292">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 6" id="KW-0195">Cyclin</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="8">
        <location>
            <begin position="228"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="9">
        <location>
            <begin position="245"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT64441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="43567" checksum="C4DE7C3D6FC6D3AB" modified="2019-04-10" version="1">MASTHIFEDQENRVPAAQRRVKREDPRTSSNVQVNRRPVLGAINTNLRKQPARAAKQGVSYETGIPQQADENACPTQKSFSTSQPSFTIHEDSCFSLGTTSNSQSASSNSTGPNPLNERLSKPLQNEEESIEDIDPSVTGLQRSLSIEQPGSSDVMEMSVCEDDLMVVETTPREDVLQSRNDDIFDVPEYAADIYQYLREAEVCHKPRANYMSKQTDITASMRWILVDWLVEVAEEYSLHTETLYLAVSYIDRFLSHMSVKRDKLQLVGTTAMFIAAKYEEIYPPDFLAEVTMLECDPFLRFLPSVIAASAVALANHTQGHTAWPSHMVESTGYSLEHLRECYVNLHRVFSRVHEPQQHAIRDKYRGTKWHGVSRLTPRSHFPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LUB7</accession>
    <name>A0A3R7LUB7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_018945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003476">
        <property type="protein sequence ID" value="ROT63191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LUB7"/>
    <dbReference type="STRING" id="6689.A0A3R7LUB7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051860">
        <property type="entry name" value="Plasmodium_CSP_Invasion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44826">
        <property type="entry name" value="SPORE COAT PROTEIN SP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT63191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="611" mass="72579" checksum="F9859C61971CC228" modified="2019-04-10" version="1">MEAFRTRDGGPRTEMEPSSNPRWRPSSNPRWRPSSPRWMPSSNPRWRPRPEMEALDPRWNPRWRPSSNPRWRPSSNRDGAFLEPRWRPSSNPRWSPRTRDGCRLEPEPEMEAFSNPRWRPSNPEMEPSNPRWAFLEPEMEAFLPRWRPSSNRDGEWRPSSNPRWRPSSNRDGGLPRTEMEAFLDPRWNGGRPRTEMEAFLAEMDLEPEMEAFLEPEMEAVLEPRWRPSSNPRWMPSSNRDGGLPRPEMEASSPRWTRTEMEAFLEPEMEAFLEPEMEPSSNPRWRPSSNPRWMPSSNPRWRPSSNPRWPSSNPRWKPGWPSSNPRWRPSSNPRWRPSSNPRWSRPRTRDGMEAFLEPRWMPSSNPRWRPSSNPRWRPSSNPRWRPSSNPRWMPSSNPRWIEPEMDPRPEMERTRDGGLPRTRDGGLLEPEMEAFSRWRPSNPRWRDPRPEMEPSSNPRWSPRTRDGGLLEPEMEAFLEPEMEAFLEPEMDCRPRTRDGGLPRTRDGCRPRTRDGPRTRDGGLPRPEMEAFLEPEMEAFLEPEMDAVLEPEMEMEAFLEPEMEAFLEPEMEAFLEPEMDAVLEPEMDRTRDSSNPRWRPSSNPRWMPSSNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2J9</accession>
    <name>A0A3R7M2J9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_011701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002482">
        <property type="protein sequence ID" value="ROT70023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2J9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="497" mass="53837" checksum="A14CF25D0D8D3857" modified="2019-04-10" version="1">MGVGTWRDLLCDGIHSEDDRTCSVWFHLRFRSECFQDPPPLTPPPRRQALRPWHRRPSPPKARVAPSGVTACRHTPPLARPSPPSPPLLTLEGQGEVKQIHSTFLTLKPLLPLPSPPLRTPPPPLPLSSHPLPPLPLLSVPPSLPSPTFSTLLISLLSLFPLPSSFPFPRNPSPPSLSPSTSFPYLSLLPISPSLLISPTPSSLSLPQPPPLHISLFILLPSPSSPSPFSLSSSCSLPPSSSPPPFFSFYSSLLLSPSSLRFFFLLLLLTSSSTCSSFSFTSLPSLNVPLPLLPHFLTVSSSSLSSPPLHALPLPSIPLPSLFLFPPSLFSHFLLHSLPILLLPCSFSSSHFLLLYLFFIVPLLSLISSSSSPLSSPFSSSSSTSLPSPFSFSSFLPSLSTILFLSFPFRFSLFFLNLLLLFLIFYIPHLPFLPLPPSTPYPPPPPPILPNLLIFSPETHPALTHMTSQGHVTAPASRPPLDVDAATPSIGITKKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M305</accession>
    <name>A0A3R7M305_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_011257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002421">
        <property type="protein sequence ID" value="ROT70471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M305"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT70471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="438" mass="45841" checksum="3324CD83958C84B8" modified="2019-04-10" version="1">MCIIHHIFSPPLSYPSSLSPSFLFLPTPPLLSSLPSFTLLPLPTYSTTSTPSLPPPPPSPLPTFSPRFLFLLRPLSPPPPPLSSPPPPPSFILRTSYSPLFLSCLPPPLSSPPPRPLSLPPPRSSNSSTTSTQPPHPSLRPLSLPPPPLFFLSPVFSPYPPPLSPSLSPSPLLHPLSLPPPLLPTPPSPYLTPPPLSLHPSPTTSPLPLSLPLHLPLSTSSPLPPSPSLPPPLSLYLLPLPTTSLPSPYPSPLPLPTSSLSPLPTSSPLLLSPPLSLPLPFSPTTPSPLPTSSPLPSSLPPPLSPLPTSSPLPTTSPPLPPPTSFPSPYHLPSLSLPPTLPYSPLSLTSSPSLPSSPLPPPPSPSHLHRPLSLPPPFFSLPTSPPLPTSSPLPTSSLSPLPLPLPSPSLPPSPLPPLRSLPLSLPSGAHCNYLWESRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4N7</accession>
    <name>A0A3R7M4N7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002248">
        <property type="protein sequence ID" value="ROT71786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4N7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018629034" evidence="2">
        <location>
            <begin position="27"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="691" mass="74058" checksum="C8E43F0D71B432D7" modified="2019-04-10" version="1">MSLLILRLVYPPCFILLLLSSGGAAARSSQQLNIGKGFRARAVSAVIQLHNEKTRNADGKKSIRAAEGGGGGEAPRALEPHEPRVEARFGGVRPNIMTRARSRANPLAPCTRSSVSPAAPGPSKGSPSAAPPFGARRAWRGRGPLPLPRRPRPWGPLGSPAPRWRRRPRDVITPSPARCDFSPTALGASCRRPSRLASGRPAEEGEEDAVSAPTAESSGLPGPLATRAVSAPHARNGDQRPRFCRLRRVPPPPHPPSPSSSPTAYHLPSPSLPHHAPPFAQPSLFLLPFPITQKKKKKNRYPLLTIPPAPSSSHRLTLLPSSYPSPALLHTPTPLPSFLTHNPLSSPLLIATSLPSLSPHRHVLLSSSSSHLSLFAPLFSSLLQQDAPFSTHHTSSLPPLHIPPSPSSSTSLFLPHHNPPPLLLMPSSSYPPFLLPHHIPPSSHPSLFPPSSQPSLSPSSHPSLLSSPLRSLPASHPSLLSLTPHIPATSSLPAFTTQSLSPPHILSLPSLLHNTSHLVLVLHIPHLFLPSSNTTPPRRNLPLCSAHASSLPSSQQRLPLIPITLTSHLSFTVPPAQPPLSAPEHNQLPLSCSASQPAPLSLLHIPRLFLLLFPLRRCRPQWPPLSLPSSTPHIDASLVPSLNSYPSLPLPPPLQPILFPPSSQRLSSSLASQRPPFSRSMPHILYLPPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M5Q2</accession>
    <name>A0A3R7M5Q2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002114">
        <property type="protein sequence ID" value="ROT72721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="434"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT72721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="574" mass="61715" checksum="FC69B000C4CFA311" modified="2019-04-10" version="1">MSWRESSASDVAAKSLSCRWESSGSMSAVEAQRSMFAGESSAPMSLGWGDVSTASMSLWESSASRCRMGEESARYVGYLAQRRCRWESSASCPWGRAQASMSRADAQLRCRLGRGSAFYCLLVRDSASSRWGRSSCVDVAGGELSVDVAGGELIVDDRGREPASMRGGRLSVDVAGGELSVDVRVGKSSRRRVAGEKLSGRCRWGRARLDVARGELGLDVAGGELSLDVAGKSRCPLGESSASMSLGRAQLDVAGGRVSVDVAGRARADDPLGKLSHVARCRWGELSVDVAGESQRRCRLGSFSVDVAGGELSVDVAGGELSVDVARWGELSVESLGESSASMLAGAESSASMSWGELSSCPWKHSRRVLGRAQRRCRWXGKHRGSFSKRKDNHESLSQISTREETPREIKKNRKQKGKKIMMITQPHSPTPLTPHLHTPTTAPHLHSPTPSPHTPHTPHPSPPPPAPHTPHTLTPHTLTLTPPPHNPSPPQPLTPSAPTTPTPPHPYYTTTPPAPAAPHPLTPTHPHPLTPTYTPSPPHPTPTTPLTPTPHYTPHYTPHPHSPTPPQRRSWHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M6Y2</accession>
    <name>A0A3R7M6Y2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002000">
        <property type="protein sequence ID" value="ROT73722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M6Y2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT73722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="390" mass="43466" checksum="DE0D77A61F4D467F" modified="2019-04-10" version="1">MQKDKKPRAREGAGDAPHASPARVAWRGGGGGAVSTNQFGDGGAGEAGRLRRSRAASTREGASEGARGRGSVGIHTLFLFSSGIQTLSFLFSSWYSTLFLSLLKFGIQLFPSSSQVVFTLFLSLLKLVFKLFPSSSQSNSFLPLLKLVSTLFSFSSQVVFKLFPSSLKLVSTLFSLSQVVFTLFSFSSQVGIHTLFFLFSSWYSNSFLPLLKLVSTLFSFSSQVGIHTLFFLFSMVFTLFSSLLKLVFNSFLPLLKWYHSLSFSSQVVFKTLSFLFSSWYPHSFLSLLKLVSTLFSFSSQLVFTPFSSSSQVGIHSFLSLLKLVFTTFPSSSQVVFKLFPSLKIQTLFFLFSSWYSLLLSLLKLVFTPFSLFSSWYSTRYSLFLSSSPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M720</accession>
    <name>A0A3R7M720_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002624">
        <property type="protein sequence ID" value="ROT68895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M720"/>
    <dbReference type="STRING" id="6689.A0A3R7M720"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000166">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018609719" evidence="2">
        <location>
            <begin position="16"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="3">
        <location>
            <begin position="30"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT68895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="276" mass="29434" checksum="7826B612C21FD42B" modified="2019-04-10" version="1">MKTLILCVLLAGAFAAPSRKPTFRRGLNKIVGGTDATPGELPYQLSFQDISFGFAWHFCGASIYNENWAICAGHCVQGEDMNNPDYLQASRCRRTNQDVDEGTEQTVILSKIIQHEDYNGFTISNDISLLKLSQPLSFNDNVRAIDIPAQGHAASGDCIVSGWGTTSEGGSTPSVLQKVTVPIVSDDECRDAYGQSDIEDSMICAGVPEGGKDSCQGDSGGPLPALTPAPPTWPASCPGATAVPRPATLACTLRSPTMSIGLRQCCLIKLFNMYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M929</accession>
    <name>A0A3R7M929_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transmembrane protein 208</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_006146</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001787">
        <property type="protein sequence ID" value="ROT75315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M929"/>
    <dbReference type="STRING" id="6689.A0A3R7M929"/>
    <dbReference type="OrthoDB" id="10012212at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT75315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="173" mass="19729" checksum="7BF23087374D1EF3" modified="2019-04-10" version="1">MVVQRGKQGTKGQKQIIQENTDTLNFYRNMILGTAGIYFGIGMLFFSEFPTFDLILLGVAGVVFTGSYRFMASMAFVKKDQSGTILDEGCDLNIEGGIAEHVKDLIILTSGVCLLSTISPYFWLLWLLAPCRGMQMLWTNILGPWFFQPAPEEPQDKNLEKKQRRLERKMKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MDE4</accession>
    <name>A0A3R7MDE4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_002417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001319">
        <property type="protein sequence ID" value="ROT78865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MDE4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="470"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="476"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="698"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="727"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT78865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="823" mass="87428" checksum="3D10C48DD5FD941A" modified="2019-04-10" version="1">MHKGIQRANNKNRTIAVYEYHLTSPVPPVSLSPPPSLPPSPSPTSFPFLPLPPYHPPTNPPSPHPRSTGSSIDTHTTLRHSSYRNPSSHPHLTSLTHSHPLPHCGPRRGEPPYSPTHPPIASLAISHPYSTCPRLRSTQSPLSTLPTRPSSCAASAHAPTPTGPILPSPPQSSTHTSPRPSVSPTLPMLPPPRLHPFTSHHLITRELHSLPPLPAAVHRISQPLVVHLPPSLLLNPSSTPSSRSPITSSLPQACLPPPFPLHPTFPPHLPSPPPPLHWHLSLSLTHLLSSPHLTTLSLSSHHLPAPQPHPLPLSTFHAPAPILSLSTLPTPPPSPTSHWSSYTTLPIILPSPHPFAIPCFRLRPPPTRPSLSLFPFSQPPTCPPLCARSSTAPISPTPYLPTAVPPLIAICPPSPYSHLSFLSSLRISLQLPPSTLSLLTHLPVPHLHALLPLILLHLPHLFPLLPISQPHSTPSSPHPSPTPTPTLPSPHISTPPPPLPSPHPSLDISHLSSPISLSPSALLTHLPAPPPTPPSPHLSPTLPPPFPSSSPHLPPFPLLTHLPPPPPSPTSPLLPLTHPPSHPLPPLPRPHHPSPTPPHPLLSSIPSQPISHPAPPLTPSSHLTLLHPTSPLCSSTLLTHTTLPLSSIPTTPTPSSPPTLPSPHPSPTPTSHPFPLLTHSLLPPPTHPFPFPLLTHLPAPPPTPSLSSPILPPPPTPSLSSPISHPHLPPLPSPHHLPPPPPTPSLSSPSLPVADVVGEDPPVLAGRVRGEPRHLQAAGGSGGDLDVPRRRPGGLSLRHELVLLTPPPYRTAFTPRLRPIIPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MGN6</accession>
    <name>A0A3R7MGN6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_005463</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001705">
        <property type="protein sequence ID" value="ROT75977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MGN6"/>
    <dbReference type="STRING" id="6689.A0A3R7MGN6"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000063">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="225"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="256"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT75977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="284" mass="31287" checksum="D775CA4940AC0FE4" modified="2019-04-10" version="1">MFRNQYDNDVTVWSPQGRLHQVEYAMEAVKQGSATVGVKSATHAVLVALKRASSELAAHQKKIMPIDKHIAVSISGLTADARVLSKFMRTECLNEHFSHNQALSLSKLMQRVGAKMQIATQRYDKRPYGVGLLVAGFDEDGPHIYQTCPSANYYDCKAMAVGARSQSARTYLERHLEEFLSVTRDELIRHALRALRDTLPNDVELTNKNCSIAVVGEGEELSIYDDDDVNPYLEGLDQEERRGGAGTSREAQPAEAPADGDASADQPPPPPSDEQPQADSMETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MH51</accession>
    <name>A0A3R7MH51_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Niemann-pick C1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_020508</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>cholesterol(in) = cholesterol(out)</text>
            <dbReference type="Rhea" id="RHEA:39747"/>
            <dbReference type="ChEBI" id="CHEBI:16113"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004036">
        <property type="protein sequence ID" value="ROT61660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="6689.A0A3R7MH51"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015485">
        <property type="term" value="F:cholesterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042632">
        <property type="term" value="P:cholesterol homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030301">
        <property type="term" value="P:cholesterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030299">
        <property type="term" value="P:intestinal cholesterol absorption"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1640.10:FF:000008">
        <property type="entry name" value="NPC intracellular cholesterol transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1640.10:FF:000010">
        <property type="entry name" value="NPC intracellular cholesterol transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="12" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="553"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="586"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="616"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="659"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="692"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1003"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1030"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1062"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1096"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1133"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="17">
        <location>
            <begin position="552"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT61660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1281" mass="142293" checksum="B9AC6A4D6E07A1DA" modified="2019-04-10" version="1">MDLMSRDPGGNISTCCDADQVTAILTQMAVGMGLLKRCPTCVRNFRMAFCYLTCSPDQSDFMNVKEVKKATDTNKTVISSLDVHITNDFINGVYSSCKDVAMPSTNEKAMSLMCGAWGSYYCTGQRWYDFMGSTSNGYSPFQIDFIYKEESGSEFKPFNKTIIPCNQGVTNDSRSCSCLDCEESCPVPPPLPPLPQPFTIFGLNGMEVVMTLLFIVFATAFTVVYICFSCRARSIDMTDQSGAVAGDEPSFFEKLGSSLEDYLERFFTSWGTVCADHPWTVLIVGVLISIGLSVGIIYLKVTTNPVELWAAPNSKSRIEKDYFDKNFEPFYRTEMLIIRPKGVDKVPHQTPNGTEMWGPAYNQTFLAEVFKLQNIITQEVHGKVDDKDVYLEDICFTPLSPVNNNCTIQSVVNYFQNNEDNLNLTGTSSFGLPYTYIDHIDLCFRNPVAMDTTLDIPCLGEYGGPILPFTALGGFLNGSQILGANPPYKDASALVISLVVNNFNDKEKVEKAKAWEEAFLKFIKDYDNPMMDIAFSAERSIQDELQRESEGDVITILISYCIMFAYIALALGSYTRCSRVLVDSKITLGLGGVLIVLISVSSSIGVYGYAGVPATLIIIEVIPFLVLAVGVDNMFILVQTYQRESRRPAESRSEHIGRVVGQVVPTILLASCSEVACFFLGVLSGMPAVHAFALYAGLALTIDFVLQITCFVSLMALDAKRQEENRLDICCFIKGSNKEGTSPEGPIQKFFKLVYAPMLLSRIARPVVVVVFYLGKYLSVGPPVYFVLKGGLNFTNFSDQNKVCGTVDCDMDSLAMQVYYAAHRANRTFIAQPASSWIDDYMDWSIYNLDSPSGDVPCCRVKKDGTFCPSSDYESDCDDCNINLTDDGLRPDPDSFMQYLPFFLEDVPGETCPKGGHAAYGQAVKIVTTDKNETAVGASYFMTYHTILKTSKDYYEALEWARDISENITNTLNEGQKEPVYEVFPYSVFYVFYEQYLTMWHDVLKSLGISLVTVFLVSIVLSGLDIASSFVVMATITMILVNLGGLMYWWGISLNAVSLVNLVMAVGISVEFCSHITHAFSLSLEDTRVLRAKDALITMGSSVLSGITFTKFGGILVLAFAHSKIFQVFYFRMYLGIVLFGAAHGLVFLPVLLSFFVLLLFYLEAGAILLFDGRSDQQLIARAAKREQTVRSNTRNRSGIGPRNTHPDCNLVAYHQPRPNPNRCRIQKRHWKHIAESFHGSMSMSDEVPEPTFINVESDMDTHLVQPEIHPSYGGTNNVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHB8</accession>
    <name>A0A3R7MHB8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Arrestin, lateral eye</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_020368</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003982">
        <property type="protein sequence ID" value="ROT61821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHB8"/>
    <dbReference type="STRING" id="6689.A0A3R7MHB8"/>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF23">
        <property type="entry name" value="PHOSRESTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="4">
        <location>
            <begin position="122"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT61821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="238" mass="26176" checksum="9F8421B1EA302880" modified="2019-04-10" version="1">MGLHFSKELELVNTEVAPHAGDVQMTDAQERLIKKLGANAYPISVNLPENAPCSVSLDGGSEGSTQPLGVIYDLRLYVADRKEERPHKRNSVGFAVRKVQYACPGSSNRQPQTLVSKGFTLSPGRLNLEVTLPQDVYFHGQPIEATLSVNNVSKKTVKNMKAEVVQHVEVTMTNTHFSRVVASLESREGCPITPGCNLTKTFSQPCCLRQQATLRHRPRRSSQGPGRQLGIVYLGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHR6</accession>
    <name>A0A3R7MHR6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000761">
        <property type="protein sequence ID" value="ROT82890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MHR6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48148:SF2">
        <property type="entry name" value="PA14 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="437" mass="47447" checksum="9B87396F71C5BA08" modified="2019-04-10" version="1">MGEVRDQKTRAPPLARSSLSSSPLLSSSSSFLPSSPSPLLLSPLPFPPLSSSPSPHRPLPSPPSLPSPPLPPLTLPSPPSPFPPSSPPLSPFPSPPLSSSPPLPPLTFLSSLTLFSPLHSSLPSSPPPLPPLLSSPLSSLSSSPSLHPSPLSPPLLSPSFAQALCPLLSLSLQSFLFLTVTVIVIPLLPFLLTLVVLVYLLRLLPLLLPLLLPSTPSCVPFPSFFSFSKFLFDLLLLLLLFLLLLSSSSSSSFFFFFLFLFSFFSLFSPPPPPPSSLPSPRPLLLFLLHLLLFLFLLLLLPSLLLSLLTNYTTPLPPLLYPSSSSSFFQYLCFFSLFSHLFTPHPTLSHPPLPVTLSLSFLPFLIFPLRSLLVFLFPISPPPSSSTLKSFPLLSLLPFVSPLYPFHKILQLVSSLVLLHPVFLPSLFAFFPILPPTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MIF4</accession>
    <name>A0A3R7MIF4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enhancer of rudimentary homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_024268</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May have a role in the cell cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the E(R) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000803">
        <property type="protein sequence ID" value="ROT82567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MIF4"/>
    <dbReference type="STRING" id="6689.A0A3R7MIF4"/>
    <dbReference type="OrthoDB" id="7887808at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2260.10:FF:000001">
        <property type="entry name" value="Enhancer of rudimentary homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2260.10">
        <property type="entry name" value="Enhancer of rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035912">
        <property type="entry name" value="EHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000781">
        <property type="entry name" value="ERH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY ERH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373:SF0">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01133">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016393">
        <property type="entry name" value="Enh_rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143875">
        <property type="entry name" value="ERH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01290">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT82567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="104" mass="12080" checksum="81E069AE0ADAA41E" modified="2019-04-10" version="1">MAHTILLVQPGPKPETRTFSDYESVNECMEAGVCKIYEEHLKRMNPNTPSITYDISQLFDFIDQLADLSCLVYQKSTNTYAPYNKDWIKEKIYILLRRQAAKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MJ87</accession>
    <name>A0A3R7MJ87_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000587">
        <property type="protein sequence ID" value="ROT84152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MJ87"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="427" mass="47101" checksum="81E2CB44A09BBE6E" modified="2019-04-10" version="1">MFSTFFLPSPSLFFPLSFLSSPLLLYLFVFLLFPFYPFFHLSLSFPPPFFSFLSFSPFPFFIFLSLFPPLPLFFSLLSSFFAFHYSSILSLFHISLFFPSFFLSLFFFLTSFFFLIYASPFSPILSHLSLSPSSLLVSLFPSFVAAFILPISLSLPIQFPSFSLSFVSLFSSFIPIFPPSCSLCRASFFCPHPSSPSFSPSPSLTLLSTNPSHLPHPLYHPPPPPPLLFTSYLPSPSHPPTNPPPPPLLFNPIPLIPYFSPSPPSYLHPAPPPKTTPPITNPLHLYLPSPPHLPSHPLLFTLPTHPPPTPLFFTSTPTLLLPSHPSFSPPTPSLSSPPFPSPIPLTILPPPPPPPFHLPPPHPSFYPPSPSFSPSHPPSPPFHPTQPPPFHPHPPAPPFPPSPSPPPPPPPPFPIKTRPRPPSSAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MPE2</accession>
    <name>A0A3R7MPE2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative proline-rich protein 2-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002897">
        <property type="protein sequence ID" value="ROT66728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MPE2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="398" mass="43473" checksum="79C035BCCF5E9598" modified="2019-04-10" version="1">MNQSPHSASPPYPFVPPPPPTTSQGSHQQANHQPPNHPPSHPTTQPPTPNPPTSQTSHPTTQPPTPNPPNPATQPPNHPPPTTPPPPNHQPPTHPPSTTQPPNHPPPPPTTQPPNHPTTTQQPFTQHQPQQPNNPSPTPNHPTTHPPNHPTTQPPNHPTTQPPNHPTIQPPNHPTIQPPNHPNRPTPPNHPTTQQPTTPNNPSPNHQQPQPTQPPNHPTTNHPTTQQTLQPNNNPNNPSPTPNHPTTQPPNQPPNHPPTQPPNPTTLQPNNPTQPPKTQQPNNHPTTQPPTTLHQQPNHPNPTTTPTHPTTQPPPNPPTTTNPTPTQPPNHQPNQSQPNNPTTTQPTTPAKRLSRAGPSESRQPELRNVTRIYRCHPALVVSIVSVRWKVLWLRTRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSB3</accession>
    <name>A0A3R7MSB3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_022161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000516">
        <property type="protein sequence ID" value="ROT84649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSB3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT84649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="262" mass="29139" checksum="805F8AE9C0ABE795" modified="2019-04-10" version="1">MTEPLPLQLNKLPTGDALSHAEKDKSACTVAYTITPRTSSTMLRFVLLALLFAAATAQQVAPCRCGAFVTTDGGELMLYELPPVEVHSCDQNNPCQPAASRSSKCCLEAATWTSSLPPTRLLARCCARRWPSTANTCTPTQSSATAPGSGPATKPYNGVLGRQLLRWVLNQQLLLQVLDQELLLRVFDQIILQVLNQQQLLRVLDQELLLWVLGRQLLWRDLGRQPSRRSSAHQVLRWGFHASPVLHLTESSYTVIYKYNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MSL1</accession>
    <name>A0A3R7MSL1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Potassium channel subfamily K member 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000482">
        <property type="protein sequence ID" value="ROT84871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MSL1"/>
    <dbReference type="OrthoDB" id="6433782at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0407">Ion channel</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="297" mass="31711" checksum="059C3F26A6016482" modified="2019-04-10" version="1">MASLRTDLVLGLATELRQVLPYDLVWRTKIETYMGRLENAVLDAARAGYASRAPTWTMSGALLYSASLTTLVGPGGMTLRTGFSRIFAVLFSLGRALSSFSWRSAGLHPPESWQGMGGVGNAGIAGRQSPVSDGRGQESSAGAVTERQGAPRSPTQDASSESGLASTPLDDIRGASLGAAPSEPTRLTLSLGGPNRLILPPIRPTLATPQDWPRGWYVTCSPPCNVCTPFRWASPSSRRHRPALEPSVRPLHPVRHVCLTLVNHECLGESRLWSSTRSSYLTCCTCLLGSSLPPSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N1U6</accession>
    <name>A0A3R7N1U6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_006511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001826">
        <property type="protein sequence ID" value="ROT74978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N1U6"/>
    <dbReference type="STRING" id="6689.A0A3R7N1U6"/>
    <dbReference type="OrthoDB" id="6356316at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000018">
        <property type="entry name" value="E3 SUMO-protein ligase RanBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="1">
        <location>
            <begin position="220"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="449" mass="47550" checksum="4BA97BCFE2D60D76" modified="2019-04-10" version="1">MPLLAQAARAVVKRKKKLCVFGGSTATNAPSVFGGSPAPNSPSLFGGSSATNSPSIFGGSATSSSTSTFGGFTATTTTASSSPSIFSSSSVTSSASIFGGTVSGSIFGGAAGSAGGLFGNAKTSGSPSMFGNAVATSTENTTSSSTTKSTEGSLFSTISSGNMLSFGDLASQSNESGFGQKNTVAADAVWAAKGQPVFGKSPKKTGDDDDDVVENDHDPHFEPVVPLPDLVEVKTGEEDLEVIFSNRGKLYRYDSGSKQWKERGIGDFKILRDPATNKFRLLQRREQVHKLCCNHYLTTQLQLRPMETSETAWCWYAKDYSESLEGTDENWTALGAGDLHIQYDDDFFGARIIMTSESGETLAEHIIAIQTTVHKEGNSATWTVLNLEPQPQAVTTFKADFASVKSLEEFVAAFHEGKEYAENSGIMEQPSGEVAPEELYYGQGADEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N352</accession>
    <name>A0A3R7N352_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001703">
        <property type="protein sequence ID" value="ROT75985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N352"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT75985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="18815" checksum="435BA1256E5705EF" modified="2019-04-10" version="1">MSCPDETTINLEARDPAEDTPSSAIRKGVISKQTARPGDRKDGKTRPGRLQGPARRPGGGRTAKILAGAFRSEEDPGGRGRAGGGAGRTEQEEEDVRSSLRPPRRAAHHQEADPLPPVLLQPHLLFQAKVNKTPKRNAATTPPAWRRRPSCRRRSRRCFQDSNPVPISVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N3W0</accession>
    <name>A0A3R7N3W0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_004799</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001634">
        <property type="protein sequence ID" value="ROT76614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N3W0"/>
    <dbReference type="STRING" id="6689.A0A3R7N3W0"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11054">
        <property type="entry name" value="CYP24A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000006">
        <property type="entry name" value="Cytochrome P450 302a1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050479">
        <property type="entry name" value="CYP11_CYP27_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24279:SF120">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT76614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="523" mass="59628" checksum="0AB12518E592F300" modified="2019-04-10" version="1">MASFPKQRALWASLSRRALISRPLVTSSIQGQMAVPLEDELRSAKPLSEMPGPKAYPVIGSFPDMFKQFDPKAYHKYYLGACAKYGSTFRMVVPGFGPMVLTTKPDDCEKLLRITMHNPLRLPMASLKAVRDNAVEDFFEKKGGILVENGDEWWRVRSRVQTPMMKPKVVGTYLQQMDQVSVEFMDRIAEMQAEHGEMPSNFQFELYKWALESVGLVALNRRLGCLNPSIHEDSDALRLIEIVNDIFQALNDTETSLGLWKLFPIKPYKKLKERHEQFLDIAVRSIQQTEASILAQDPDIDHEVSLMESLLMTEGLTKKDVVTLILDMLFAGIDTTSHTLGFTLYQLARNPEIQAKLQEEVDTVLGDHEGPLLPKHMAQFSYMKGVIKETLRIFPLTLGVGRTVDKDCVLSGYAIPKGTVILALSMVSAWDEKYFPRAKEFIPDRWLRGRPLGPIHPYASLPFGAGTRMCIGRRIAEQEMYTFLARTMQRYSVDYKYKDVDILTRLVFVPSEPLRFSFTERRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7N4R2</accession>
    <name>A0A3R7N4R2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative neurotrimin isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_004158</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001557">
        <property type="protein sequence ID" value="ROT77205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7N4R2"/>
    <dbReference type="STRING" id="6689.A0A3R7N4R2"/>
    <dbReference type="OrthoDB" id="10012075at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043005">
        <property type="term" value="C:neuron projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000328">
        <property type="entry name" value="CLUMA_CG000981, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000376">
        <property type="entry name" value="CLUMA_CG000981, isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051170">
        <property type="entry name" value="Neural/epithelial_adhesion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231">
        <property type="entry name" value="CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12231:SF253">
        <property type="entry name" value="DPR-INTERACTING PROTEIN ETA, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="53"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="10">
        <location>
            <begin position="149"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="403"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="498"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT77205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="576" mass="64039" checksum="10885F522EA08E3B" modified="2019-04-10" version="1">MIPTQSPHKTQSKQPEESPIAKHVYPLAPSHCPAAGHGVGGQRSTDREEKDAPDILDEESSSEVTVKEGHDVTLVCRARGSPKPVISWKREDGGRIDLNNGINLRVTNSEVLHIPSVSRLHMGAYLCIASNEVPPSVSKRIMLNVQFQPVLWIPNQLVGVALGMSVTLECHTEAFPRSINYWTDDKGKMILSSGRFDTVVTENSYRAYMRLKIKNVQPEDYMSYGCYAKNSLGETNGSIKVYGELVLSGWGRGEGPSWWDIKKTDFRIPTPPPPLPHSPNPNVQRFPIPFPFTFLLPLTLTSYTFLLSLPLTLFPLHPFPPSLPPYLSFPYPTPLSPSFLSRTLPTPFHPSFLPFRLSPPTLTPLPPPFTLSFTLPPPSFTLHSYPFPSSRLNPHPPHPFTLHSYPFPLSPPNPHPLTHSPLTRDTPRAHGEPARTRTDPARRGPGQVGAREPDEEPQAEGGPRERWREEGGRQRFDDDDVVSTMTADGYIEFDVQKLLGKSNRSNRKDPENKTRPDRRGQGHRSGISENHPLHNTPPTSSSPPRPRPGHALNASLVSGLLAAWLLHALAAARQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NC86</accession>
    <name>A0A3R7NC86_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein numb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_023545</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000705">
        <property type="protein sequence ID" value="ROT83288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NC86"/>
    <dbReference type="STRING" id="6689.A0A3R7NC86"/>
    <dbReference type="OrthoDB" id="10070446at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01268">
        <property type="entry name" value="PTB_Numb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000031">
        <property type="entry name" value="protein numb isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016698">
        <property type="entry name" value="Numb/numb-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010449">
        <property type="entry name" value="Numb_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006020">
        <property type="entry name" value="PTB/PI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47368">
        <property type="entry name" value="NUMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47368:SF2">
        <property type="entry name" value="PID DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06311">
        <property type="entry name" value="NumbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00640">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017607">
        <property type="entry name" value="Numb/numb-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00462">
        <property type="entry name" value="PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01179">
        <property type="entry name" value="PID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PID" evidence="4">
        <location>
            <begin position="100"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="489"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT83288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="612" mass="65943" checksum="D959A23EDBF93F11" modified="2019-04-10" version="1">MSWPGPPRTTATSCSSSYRKGQGTMKEPTHLPLSATLSAPPGLCSTKVEGPSGSRGRRMDRLRRSFRESFRRKKDHHHVTEASKPHQWQTDEAAVRAGTCSFPVKYLGCVEVFESRGMQVCEEALKVLRNSRRRPIRGMLYVSGDGLRVVDDETKGLIVDQTIEKVSFCAPDRNHEKGFSYICRDGTTRRWMCHGFVAVKETGERLSHAVGCAFAACLERKQKRDKECGVTMSFDPTTSTFTRTGSFRQMTVTERLSDPQECKPIEPVPVKKVENPHAIARPHATPLMLQRQGSFRVFQHLSQSSPFKRQLSLRLNDLPSNLERTRSMSLDNSATNAMTTNNNIQPPVTPIPEISPMVETKPGDAVSAMCQELSAGLSLLSNFSDPFSSPESSSPSHNSFTSSTAATTTTTTSAVTAFSNVTTTVATSQSVAPTSQVLLPSVEPIREENPWAGPAVNGQASKAEELINAGESAGWSRGEEWLSQINSNSKITNGTTTPPPGTQPANSTFAARRNPPIGQVRSVSLGGAPQSGAPYAAPGNTGDPMSSSWSATNGTRGSSPANYLGGAPAPSVGGSTGPDPFDAEWAALATRNANPNNPFLPNNVTKAFEVQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NCM2</accession>
    <name>A0A3R7NCM2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Homeobox protein engrailed-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_023232</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Engrailed homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000665">
        <property type="protein sequence ID" value="ROT83589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NCM2"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030182">
        <property type="term" value="P:neuron differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050720">
        <property type="entry name" value="Engrailed_Homeobox_TFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000747">
        <property type="entry name" value="HD_engrailed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020479">
        <property type="entry name" value="HD_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019549">
        <property type="entry name" value="Homeobox-engrailed_C-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019737">
        <property type="entry name" value="Homeobox-engrailed_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000047">
        <property type="entry name" value="HTH_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341">
        <property type="entry name" value="HOMEOBOX PROTEIN ENGRAILED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24341:SF6">
        <property type="entry name" value="HOMEOBOX PROTEIN INVECTED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10525">
        <property type="entry name" value="Engrail_1_C_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00026">
        <property type="entry name" value="ENGRAILED"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00024">
        <property type="entry name" value="HOMEOBOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00031">
        <property type="entry name" value="HTHREPRESSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00033">
        <property type="entry name" value="ENGRAILED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3 6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="5 6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="6">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU510713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT83589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="227" mass="25611" checksum="2271BDCCB28394C9" modified="2019-04-10" version="1">MSPRSRRIKAPRPQPREKRPRTAFTSEQLARLKKEFEENKYLTEKRRQDLARDLGLNESQIKIWFQNKRAKIKKASGNKSSGLAAHLMAQGLYNHSTVPFVFRPPARAHSQFNCCQCSSNEHTARGATSPCRLWGTRASASSWRVTWLTPRRSPPAAHALPRPYPGLLPSAREWRTKPEFPELRGAEDSSAPGDAASDCQRLSLALRAPPPPSLDPRRPVSPQPQHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NFA5</accession>
    <name>A0A3R7NFA5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_009534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000221">
        <property type="protein sequence ID" value="ROT85663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NFA5"/>
    <dbReference type="OrthoDB" id="6371339at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="3">
        <location>
            <begin position="465"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="732"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT85663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="746" mass="82635" checksum="FF2EB571CA6592BF" modified="2019-04-10" version="1">MWLSGAFFGQNNVGHRPTEHNRNHNEPLPGTMMMAGAEGSDSSTEPELPEAQIQAGRPLLNCVVAGTKVLAFLDSGRASSASFNGVQLGVSFSGAGSLGILTYHEPEAVLRCCSASGGDREGAMRCARRVTCPPRAGRFVRCLVNGLKGGLACVESDTAKVLVPRSLVDLSQPEVDVWVVNDQTVPVEIEQGFVLCYAAIVEVSLNRLEYDAESMDQDSGVNPEDVGSSSGDSRGALGMASSTPIDDGSELDSLMADFETAGAVSVPRVDLAHLSSVQREQLVQVLDRYPDLFNEGLPPGVVPHMKHKIKTTDDQPVRVKQWRLPESTRQYICGVRQDACRRDHRPLVSVFRKPTASVRMTRWAHELTFYDFELLYKPGRVHHVPDLLSRQIAAIDDLDSPLLQPDLVERHQRDDPLWQQLIEYLEEGRLPPRRIPLPLDQFELRDRVLYHVKSNNERALLQLVIPRSLRGAALDAVHAVPSAGHQGVHRTYQRLRDHFYFPGMLAASRKYVASCTACQRRKGAIARTPLQSMPDVAEPFERSPWISSLLPLRHVETSRDSHFPLVGSNHVIYAEGALPSLRSKLRAARVAAGEAARKARERWTADHDRRRRARPREYNEGDLVFVHRSVILHPSHGTRPLGPRWLGPVRVLKKLGPVAYVVRRPNSDGQEVTLHPNKFKAFRVTAEFVPPDDFPRLDGTAPPDPESDMGPLQDPGADDLLDSESSAPSSEGVDDEPWDPGSDWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7NTU4</accession>
    <name>A0A3R7NTU4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015429</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002918">
        <property type="protein sequence ID" value="ROT66550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7NTU4"/>
    <dbReference type="STRING" id="6689.A0A3R7NTU4"/>
    <dbReference type="OrthoDB" id="445896at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="417" mass="45401" checksum="FE31B05F5D808FD8" modified="2019-04-10" version="1">MKKAKALKARQPLDLTRLHKGFHSTPDLKAEVTGTLPAFTIEEKRKSVSQEDLFVTALNERNSRHSLVCPPPHSSTLERITVGSPESKESWQSGEEGTEEESSDSPNISPGPLEYQAMPVSPGVQSSFRPTDCAKLYASPEEIKTVGYRSPEMMATLNRKNASVKSRSQSLPPSTNRPSVQRGSPDKDTSLDSGIYLTTYSTFRGTEGETSRSREVVSPSSAGKAPSLVLQVKPTQDQVVASPAPDIPEPDYSSDEDHTYNSQDESQSKKTRTLKKKKPTVAFSPNLVTSTSESSDVPHYAAPAKHPTPLAGNFKDLIAQKAAERQARQDDGPEKQTRSATSSPSSTGEREMQHSMHAGQVPSSAPSSLQMRATLPRPPQVHQALEKLSTPSEPGHQSTVTGTLGRSRPTTREQHWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P4P5</accession>
    <name>A0A3R7P4P5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cellulosome anchoring protein cohesin region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004331">
        <property type="protein sequence ID" value="ROT61151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P4P5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="683"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="733"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="778"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="800" mass="91127" checksum="D088D2CF2F2E805D" modified="2019-04-10" version="1">MEPSLPRPPFLGFVCFVVPRVVGGGGGPLQHTPKQRPTPKQRPTPKQRPTPKQRPTQTPKQDRLPSKDRLPSKDRTPKQSPKQRPTPKQRPTPKQSRLPKQRPTPKQRRLSTDSKQRPTDSQADRLDYRLPSKDDSQARRPTPKQDRHQSKRPTDSQAKADSKQRPTPKQRDSKQRPTPKQRPTPKQRPTPKQRPTPKQRPTPKQRPTPKQRPTPKLPSKRPTHKQRPTPKQKQAKRKRPTPKQRPTPQPTPKQRPTPKQRPTPSKTEQRPTPSKGPTPSKDRLQAKTDSQAKTDSQAKKSRLPSKDRLTSKDRLPSKDRLPSKDRTKAKDRPKQIPTPKQKTPKQRPTPKQTDFKRPTPRPTPKQRPKQTDSRRKRPTHKQRPTPKQRPTLTSKDRLQAKTDSKAKTASKDRLPSKDRLQAKTDSQARPTPKQTDSKQRPTPKQRPQAKTDSQAKTDSQARPTPKQRPTKDRLTSKDRLPSKGTPKQRPLQAKTDSQAKTDSQAKTDSQAKTDSQAKTDSQAKTDSKQKTDSQAKDSQQDRLPSKDRLPSKDRLPSKDRLPSKGRLKASKPTPKQRPTPSKDDSQAKTDSQAKTTPSKDRLRLQQRPTPKQRTDSKQSRLSKDRLPSKDRADFDSQAKTDSKQTDPQANRKRPTHKQRPTPKQRPTPKTDSQAVTSQAKTDSQAKTDSKQRPTSKDRLSKQRPTPKQRPTPPSNRLPSKTDSQAKTDSQARPTPKQTTPSKPKARLPSKDSPSKDRLQAKTDPSDRLPSKHVRQITMDFTRQSHQLFSQGRKRSSPSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7P5U3</accession>
    <name>A0A3R7P5U3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Organic cation transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_020164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003865">
        <property type="protein sequence ID" value="ROT62008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7P5U3"/>
    <dbReference type="OrthoDB" id="6346347at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT62008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="256" mass="29108" checksum="0485929AE3BCFF98" modified="2019-04-10" version="1" fragment="single">FDLVCSSDYLRATYEQMYMFGMLVGAPLAGILSDRFGRKTVFSVGIVSYLVLSIASCWLPSFTAILASRFFLGFLHPAGLQVAYVLALDSFHPSPTHIAGHQPNINATFLKECILWKAMEVCESRYRSIVGVLLALPWALGTIAWGIWAHLLRDWKWLQLAVSLPGLILLPVLWFLDESPRWLVIRGQFDRAQKILEKAAHWNDVQLPPAGQLERLMRNIQKETILAKEEIMADHEGAVPLRRKMWLFGLKIFVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PBM4</accession>
    <name>A0A3R7PBM4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001034">
        <property type="protein sequence ID" value="ROT81034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PBM4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT81034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="463" mass="51682" checksum="B5CAB7A0FA351C77" modified="2019-04-10" version="1">MTRPQSPPQTRPTITTAQTIEQTRRTKFHRTRNNSLRGGPPTQSNPLVTPPGHTQAHNHPSPPETTSNHREETKAKTEKETGHHTQKKAKNVKKKSPAHNGLAHNHPCPQQQYRRNKPSGQTTKGIEKRTRRTGRTPTKCLISRHPNNHPAHNHTTPSTIPTHDTHPQHKSQTPPRNKYHPPDNHPKKPKNKYNPPTITTHNHPPTKTPPQCTRPQITPPQSARPQITHPNKSPHTQSTHHPQSPAHNPPAHNPPDPPTNHPPPTITRPQITPPTNHHRTHNHPPTITHHNHNHPPTITPPHTITRPQSHRPQSPPTIHPPQSPAHNHTTNHRPQPLAHNTAHNHRKPHHPPTITHHPPQSHNHPPTSPAHNPTHNHPPTITPPHNHPPTSHPPTTTRPQSPTHNHPPPITAHNHPPTITPAHNHPPTITRPQSPPESSLSLSPVFPSPSTFLVSLSKTAVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE36</accession>
    <name>A0A3R7PE36_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AFG3-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000700">
        <property type="protein sequence ID" value="ROT83332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE36"/>
    <dbReference type="STRING" id="6689.A0A3R7PE36"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="167" mass="18148" checksum="0D5A5AB1307E0180" modified="2019-04-10" version="1">MAHRLLTAARRLDRLLQKVKKTGSVDPNVVGSQLAYLDLPNGTILLQQWRQFCQKPPRGFEKYFRGASKQGPKQQPQQKADTPPPQQQSPNKPSTPKDPFNLSLFGSGSKSGKGGGRGGGGKPLGEGSDRDRWVAMAALAAMGLLGLLPFTRWATKKSRGRSSPRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PE49</accession>
    <name>A0A3R7PE49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_023465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000697">
        <property type="protein sequence ID" value="ROT83371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PE49"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT83371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="374" mass="40728" checksum="58B967D99ED4204F" modified="2019-04-10" version="1">MTRLNLRGLARGGILSPRYLCLPISNLYLPSPSLLPIFILSSSSPPFLLPSSLSLFSGPFSLPFFTFPSPPPPFSGSSSFSFSPPFLPLLSLLPILPQSVTPLFVSLPPPVIDLLTTCYLCFFSSDSFSTLYLSFYSFSPLSPLYLIVFGLRDCLFLRSLSSVSFSVCSLLPPLSSLPRILPPFLYLLFILSSTSSLLFICLLFPFSLYPTLLSLPLPSPFGPLLHVHSSPPLCFLPFLPHLVLFSNSLFPFPLSPLFHLTLPSLPPVLSSSTRSPSIHLHHFPPPLPVPLPIPLPPSPPLPFPPSDPLPSTPPLPSTHPFPPPHPFPPPPLPSTDPLSTSTLQSTPSLALLTNLLQPEQICHDRPGRESIDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF19</accession>
    <name>A0A3R7PF19_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_017999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003331">
        <property type="protein sequence ID" value="ROT64081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF19"/>
    <dbReference type="STRING" id="6689.A0A3R7PF19"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT64081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="385" mass="41713" checksum="C6905CC042DD1D0B" modified="2019-04-10" version="1">MTSTAENGAQAHGKGRPRDAQGVGVERGCGTVTARGRRRDQCLYRDVKSVTSWGRRPPLASRFISTFCSPFPFPFHFLALSPCLSPLPFSSPFHFLSLSAVISPPHPCFVFPSLPSSRGSIFVFLPSFYLLFFRLILFVYFLSSIDFLRFPLLSFICGFSLFLPSFPLSFLLFFFFPLAFLSLFLLPLPFFSFPPLPPSIPLSFSPSTHSLFSLLTFLSLFPPPPPSLSPPSIPPFSVTLSLPSIPSLLPSSPSPSSLPPSSRSSLIPFPPPPPSLSLPSIPPFSVTFPSLPSFPSSPSSLNPSLPSLPSSLPSSTSSSLPPLLLPPFPPPPLPLAPLPFPPFFSPFTSSPPPHPTPSRRENCRCVKARTSRHFLGRGTGSASVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PF83</accession>
    <name>A0A3R7PF83_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_021712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000460">
        <property type="protein sequence ID" value="ROT84972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PF83"/>
    <dbReference type="OrthoDB" id="6338195at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00473">
        <property type="entry name" value="PAN_AP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57414">
        <property type="entry name" value="Hairpin loop containing domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="312"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="387"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="669" mass="75582" checksum="A2C44EF8828EA4DB" modified="2019-04-10" version="1">MADIGEQKGRPLPVRLDVTIYRDDNASAVLSRYTVNLLHMQTSFLSTNFNPFDVRECMDIPSQRTWLKITYAGIWEHGASQNPDEFKKILLEQIQGGTDMSPVRLPEVQLDHDQEFVFATVLLLEPAPYHLQFKQLVDRKPTDDDVQLEFATDDDDMCASGCLRFSTFECKSFYLCKTLNKNCFVSNYLNSGGSVFPVKACKHYQRAEIKNTKFQKPNQEIVDWIMTKGYLKEKYTDLKLPKVCGGFGGLGWEGRWRWEGCGWEGSWEEGRRGKGGWRSTRTLSCRRYVDGGNGGWEGWEGWGRREGGGLGSHTDDYEKLDGTVYTGDADQVIKSTDADKCAYHCSNATSITCRSFDYCEKKKTCYLYEQRTIDMPPEMINHTVPDCSHYSRDALVDFKKHENQVLEGSRDRYLKFVSASYCAQVCEDEPDYGCNGFDFCEEPEDVTCFLTSDHYTDEGVDIGNSPTCSHYSRSHTDDYEKLDGTVYTGDADQVIKSTDADKCAYHCSNATSITCRFAKTSLDYGCNGFDFCEEPEDVTCFLTSDHYTDEGLFFASPKNGTETRVKWVCVALHMTRLYATRPSMPPFPSPPPSPLSLRTREKLVPISPPSPSAALASPTPHPTPIDSIRAWQLTPLLPPPPTSPMTRRVWESRGCVSLPREVVATTPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PG24</accession>
    <name>A0A3R7PG24_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_016656</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003093">
        <property type="protein sequence ID" value="ROT65376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PG24"/>
    <dbReference type="STRING" id="6689.A0A3R7PG24"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06822">
        <property type="entry name" value="PLPDE_III_YBL036c_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000007">
        <property type="entry name" value="Pyridoxal phosphate homeostasis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine racemase N-terminal" evidence="5">
        <location>
            <begin position="47"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT65376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="269" mass="29871" checksum="EAE533B34D59755D" modified="2019-04-10" version="1">MAMDTLVCNLQERKQMLRMMADTEVAKALLSVIERVNVATKARSPEIAALCRQPRLVAVSKTKPKDMIIEAYSAGQRHFGENYVQELVEKGHDEEIIEKCPEIKWHMIGHLQSNKVNKVIGIPNLDCVETVDTAKLATTLNNAVQKRGLDKKLKVFVQVNTSGEERKKSGVHPDNVNELVGHVTKNCPHLTLLGLMTIGAFDHDLSQGPNPDFQTLLKTRAAVCETQCIEPQDVELSMGMSNDFEHAILIGSTNVRVGSTIFGARNYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PGU1</accession>
    <name>A0A3R7PGU1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002997">
        <property type="protein sequence ID" value="ROT66047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PGU1"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="177" mass="19523" checksum="5882AD28537ECDF8" modified="2019-04-10" version="1">MAGSRMTQRVSPGHVCSPPPLVTPVTVVVTGPTSRWLRLLWKPIPDSYRVAFLRQTELLSRMEQLNKANACDTTSGSMSPRVTTTDASLEGSTVSSSVPDYALCSEDDSEEQLRENPECMLLLSPTIPRKVPAHKFSLTPKPKDALIKKYQAEVEDEIKMDLTTPHTSINIALDCPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PN34</accession>
    <name>A0A3R7PN34_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001541">
        <property type="protein sequence ID" value="ROT77301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="2823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="675"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="720"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="827"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="870"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="913"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1062"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1180"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1247"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1280"/>
            <end position="1307"/>
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            <dbReference type="EMBL" id="ROT77301.1"/>
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            <dbReference type="Proteomes" id="UP000283509"/>
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    <sequence length="2823" mass="300630" checksum="6A181584B8E9CFDE" modified="2019-04-10" version="1">MTPASHAYPRPASPRFNPQPASPRYPLTRLAPRYPHPPRPADPQPGFAPGLSLNPPRPCCIPTRLAPLSPNPRLLRSAIPNRSPPLSANPGLAPLSRKHRTSPRYPQPASPSAIPNPPLPAIPNPPRPAKYFPNPPRPALIPQLPRSPPLSPTASAPLSPNPPRARYPHPASPAIAHPAVAPLISLYPPRPRYPHTRVAPLSPTRPRPRIPHPARPLSPNSASPAIPTRPRPADPHPAFAPLIPKPASPAIPNLASPRYPQPRLARYPQNPPRPGYFPPCLRPAIPAPASPALSPTRLPPLIPNRGLARAIPNPPRPANPQPASPRLSSAPLSPTRLAPRILAHPQTRPPAIPNPPSPAIAPLSPSPPCRPAISPTRLAPPIPQPGLPNPPRPAIPNPAFAPAYRPTRLAPLSPPASPRYPPLSPPRPRPLTRLAPLSPTRLAPLLSPTRSPPRLFPAPPLSPTRLAPAIPIHRPTRLAPPRPYPPAHPQPAPPRYPRPRLAPLLPNSASPRYPQPASPPPISPNPPRPLSPTRLARYPQPASPRYPPPPASPLLSPTRLAPLSPTRLRPAIPNPPRPLSQPASPRYPQPASPRYRYPPTRLGPAIPNPPSPRRIPNPPRPAIPNPPPARSRLSPTRLAPAIPAPPRPRYPQPASPRYPQPASPRYPQPRLAPLIPQPASPPAIPIPASPRYPQPASPRYPQPASPRYPHTRPAIAPRLFPAPPSPAIPKPRPLSPTRLAPLAPHPPRPLSQTRLAPHIPNPASPRYPKPAALAPLSQPASPPLSPTASPAIPNNPPRPAIHSASPLSPPARPVSPPASIDRLRPATRPPRPLSPPARPLPAPPRPAIPNRPRPASDPPRPHPPAPPLSPTRLAPLSPTRLAPLSPTRLAPLSPRPRLAPLSPARRRATRLPASPPAPPLCPNPPRPPLALPDPLPPPLSHPASPACPRPPQPRPQPLAPLPQPASPHPQPRSHRSRPPPPAIPPASPRCPRPSPAIPNPPSPYPPPAASPASPAKTRPRPAIPTPSPRYPQSPLDRYPPRPLPLSPTRLARYPQPASAPLSRPPRPAIPNPPRPASPNPPRPAIPATPTLFPAVPNRLSPLVPTPPRPANPQPPRPAIPTRPRPAIPNPRPPLSPTLLARYPQPASPAIPARLAPLSPHRLAPLSPAPPALSPTRLAPLSPPRSPRYPQPPRPAIPNPPRLAPLSPPARSQPASPAIPAAIAPLSRPRLAPLSPTRLAPLSRPASPAIPPHPPPPPPPRPSPPNPPPAPRYPNTRLARYPPPPRPLSQSPPPRPASPALAPSPPASPRYSLTRLAPLSPPRPLSPTRLARYRPNRLAPLSPPRLARYPPRPRPSPRSPPTRLARYPRLAPLSRPLARYPAPSPRYPQPPPRPLFPARPAIPKPAPLSSPPTRNPPRPHPQPASPRSPTRPRPAIPNPPRPLSQPPPPLSRPPRPAYPQPRLAPLSPTRLAPLSQPASPRYPQPARPLPIPIPTRLALSPPLAPLSPPRLAPSPPTRPYPAPPAPHPNPPRPAIPPPPAPLPTRLAPLSRPALAPPIPPASPAPQPASPPLSPPASPAIPTPPRPAIPTRSPRYPQPASPAIPPASPLIPTRSPAIPPRLAPLSRPPAPLSPTRPRPAIPTPPRPAIPTPAAPLSQTRLAPLSPTRLAPLSPPPRPAIPNPPRPLSPPACPYPQPASPRYPRPPPPLSPPASPRCPQPPPPAIPPRLPRYPRPASPRYPQPASPRYPRSPRYPNPPRPLSQPASPAIPRLAPLSPTRLASPAIPNPPRPAIPNPPRPAIPNPPRPLSLPPRPLSPTRLAPLSQPRPRPAIPNPPRPLSPTASPRYPHPPRPAIPPASPAIPNPRLARYPQLASLSPRLPASPPARPASQPRLAPLSPTPPAPLSPRRLAPLIPKPACPLSQTRLAPLSQPASPRYTPTRLARYPQPASPRYPNPPPLAPLPNPPRPASPTRLAPLSPTRLAPLSPNPLAPLSQPASPAIPNPPRPAIPTPRPAYPHPPRPLSPTRLAPLSRPASPAIPFRPRPAIPTRSPRYPQPASPRYPQPASPRPAIPNPLAPLSQPASPRYPRPPRPIPTRLAPYRPAPAPPRPANPAIPHPPRPLSNPPRPLSPTRLARYPQPASPPPTRLAPSPTRLARYPPTRLAALAIPPRPAIPTRLAPLSNRHPQPASPRYPNRLAPLTPAPLAPLFPNPPRPLSPPPRPAIPTRPLAPLSPTRLAPLSPTRLARYPPPRPASPRYPQPRLARLSAPPRPAIPNPPRPAYPQPPRPLSQHRLPRSPPASPRYPHPPRPAIPNRLAPLSPASPRYPTPPRPRLSQPPRPVSPPASPRYSPTPPRPAIPTRLAPLSPTRLAPLSNPPPRLPRPLSPRPRPPSPTPPPAIPAPASPAIPPRPPASHPASPAIPTRLAPLSPTRSPAIPNPPSPAIPARLAPLSPPASPRYPQPASPARPPRPAIPNPPRPLSPNPPRYPRPASPRYPPRLAPLSPTRLAPPIPNPLAPLIPPASPAIPNPPRPAIPTPRPAIPNPPRPAIPNPPRPAIPTRSPRYPNPPRPAIPAPPRPAIPTRNPPRPAYPPASPRYPQPASPSPRYPARLAPLSPPPPLPTRRPAPLSQTRLAPLPASPPPNPPRPAIPNPPPAIPNRSPLPPASPAIPNPASPRYPARLAHIPLAPLPAARPLSPPASPRYPQPASPAIPAYPQPASPAISPAIRPLSPPRLAPLSRLARYPPRLAPLSPPRLRPAYPRPPPPPPAIPNPPRPLSPPPRPIPKPASPRYPPLAPLSPPRLAPLSPTPPRPAIPRLALPARPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PNB4</accession>
    <name>A0A3R7PNB4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative endophilin-B1 isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_009648</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002218">
        <property type="protein sequence ID" value="ROT71987.1"/>
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    <dbReference type="Proteomes" id="UP000283509">
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        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SH3_domain"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
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        <location>
            <begin position="50"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="1"/>
            <end position="51"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="3">
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            <begin position="11"/>
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    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="111" mass="11597" checksum="93C5127F397C4452" modified="2019-04-10" version="1" fragment="single">LSLIPDATVGSAVVPPTTSSATSNASAPTLTSSSTTVGVDGEAKSVDEGGPWRRAKVVCDYDATSKDEMSLMMNEVVMYSSKDGELADFVMAKRGTQTGRVPSAYLEPMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PRI1</accession>
    <name>A0A3R7PRI1_PENVA</name>
    <protein>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_000903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001126">
        <property type="protein sequence ID" value="ROT80362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PRI1"/>
    <dbReference type="OrthoDB" id="6353463at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018776689" evidence="1">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="C-type lectin" evidence="2">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT80362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="166" mass="18094" checksum="8189A1999F186FF9" modified="2019-04-10" version="1">MNGLSGFFVVALAAVTVPSAPTASSRGGGCFHVLDSEETPITWEDAREMCIGLSGNGWNADLASMDTTSQLEAFAEAWDTVGANYRPYGYMWVGFTRESGEWANLDGVPLSTYSNMWREGHPHDMNMYVYIEDVTMTSGIGSRGRFYASCTMQDALGRALCRAFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTD0</accession>
    <name>A0A3R7PTD0_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proton-coupled folate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_024752</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000885">
        <property type="protein sequence ID" value="ROT82079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTD0"/>
    <dbReference type="OrthoDB" id="3026777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507:SF1">
        <property type="entry name" value="FI18259P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23507">
        <property type="entry name" value="ZGC:174356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT82079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="57722" checksum="657228204267853F" modified="2019-04-10" version="1">MARGEDREQLLQEVSDLDQQLHSFVANNSTEYGEPQEEVKGCKRFLKALQQVKNITIEPILFLYLLSWTIQSSISTNLLLDKVCIEKNYSSEICANLSSYPNNQIEVQRVVTKINMYMDLLTNIPSVLFVLFLGSWSDKHGRKLPMILPLVGSLLSTVLYLMNAYWFSLPALYILLSGVPRALTGGFITMIMACYAYISDITKIRSRTMRIAILDLFMFLGAPLGLLLSDVTFYSLGYLGIYGLSALLFLIAILYAILRIEDTRGRFSKYHLEASELAQTPGNMCKDLVDINNVKKSIAVCFKPRRHKLRTKILSLMAAMCVLVFVFGTTGVDYLYTKRKFGWTYDQYVHLGLVEVFVGVAGNSVVLPLVSYKLQVDDSVIGFVGSLFKIASLIIKGLAAQPWMLYLSSCVNFPGGLPLIIIRSMMSKIIPSDELGMIFSMLASWESILPLVSHPLCTLVYNATIKDFPGTVYLMSSLFVVISTGIFVWLIKNRNFTSPEPHVHEDEIIQSVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PTL5</accession>
    <name>A0A3R7PTL5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_004678</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01001616">
        <property type="protein sequence ID" value="ROT76721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PTL5"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1031"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase" evidence="10">
        <location>
            <begin position="3"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase zinc-binding" evidence="11">
        <location>
            <begin position="317"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT76721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1076" mass="121359" checksum="54109DBBDD14137B" modified="2019-04-10" version="1">MGKGHTVFSTLDLQSGFFQVQMDKDSRPLTAFSIPQGHFQFKSMPFGLRNSPITSRVMSIIMASLIGNTVFFYLDDLLVKKIDYLGHTVDSDGISPNSAKVKDILSFPTPREVKQLKSFLGLAGFYRPFIKGFAKIADPLSRLLTKDASFTWTDEHQQSFDTLKSLMTRSPTDDFDLSAFSRKLNAAETRYSVTDLEALAVSPSGRQARWIDTLLEFNPVIRYTPGASNKVADSLSRVPTLHLDVLDREDVKSRQRQDPTYGKLIGILESDPSATLPRRPHVPTSDLYLEDDLLFRRSSPHRQRGTRQRHSYKQLVIPEDLVPTILRLLHKAPTASHARADKAIKFARERYFFPRMASRITEHIRRYQVCPLHKGSTAAPAPALTYDVPDRPFQHVSVDILSGFSTSTSGCRYLLVFIDAFSRFCELAPIPDKSAPMSHEHFWSVLYADITPRRTPWAIPPTSSSTEKIGDYPTSPRPAYTDDYASRVIRKKQEIYSIARRHLQFERDRIIRQQHKLSRCKDITAGALVFHLASERSAPMPKLSLRFDGLYRVLQMRTLLHLLSLLHLSAASLPDNYLPRPRAILEDISTVSFISSYVEITINLDVLSYFYNTASTHLSLIDQYRHAITTDTSLTPPQVSSLLSFLSLSQADLTLFKDRLPRPHPRRQRRGLFNFMGDITSYLFGVATHDELDARFGDYERTLSSVAGKFKATFRALHAISDTVNSLNNVTRHLSIYTDTNTQLIAHKHFTLLLAHISLYQSRVRLFVDHLNTLTHDLILAVHGSVMSSLIPPSALESFIRRISAETRFIPLFLWLTPPFFTHYSSPSLHPMVHFFPLPLNGSFYGLSPDHDVILRSLDHTSLSFISSDALSSCSSVLCACFDVFSPEHSYFHSFCHRALLSDGDVQSSCLFNQLNSTSPFLLTLPDLHLLYFFSATHVSINCGSNHADREISATFLLPRSCQLSARLISLRSSHSFHFAYSPVTPTLPPMSLDLPVTNVSLPLATVRMLPSYRDDVPDLLTFDRSPHVTIGFPVLSTVISLAIAICGFLLYRHLTMRHLRIVSSASSARDDPSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7PYF4</accession>
    <name>A0A3R7PYF4_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_000304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001046">
        <property type="protein sequence ID" value="ROT80951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7PYF4"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT80951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="404" mass="43308" checksum="4FBAD9CF006698A8" modified="2019-04-10" version="1">MPSRLPTYSTKLFYFPTSFYLPPAPPPHLSYIPHLPHHLSTCLAPPTTTCPTCLAHYPTCLPHHLHLPSSPDTPLNTPWATPPPSPLLLPPLPPVPLSSLLLLPACASPLLLPSPSASSSPLLSSLSLPPVPPSAPLPSPPLPPPVPPLCSSFSSSPSCAPSAPSLSPPLFFPLLSPNSPFSPTVPPPLPSSLPLCSPLLPLLPFAPPLIPPFFSFRLVLLFLRLFFPFAPPLIPPFSFRLVLFSPSALLTLLLPSSSFLFPVLLFSLPLVSLSVCSSLSPPLRLPFGPPSLLPSVLLFLPSVRLSFSSSPTFFLPPSLAPLSPLPYISSLLPLSHLPPPFFFSLSFPSSFSFLPLFPNSFPPPSAIFLSRRKSLEAAPLAVASCKKSRRMQQISRDTARYGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7Q2N9</accession>
    <name>A0A3R7Q2N9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_022383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000543">
        <property type="protein sequence ID" value="ROT84425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7Q2N9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="860"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="652"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="756"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="917"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT84425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="956" mass="103812" checksum="923A8BF9C01112DB" modified="2019-04-10" version="1">MTSRRPARMTSPPAHTPSRVSFHYVTIAFARSALTSILFSSLPFSFIYVLPSPFHSSLVLFSSPLLYLRPSFTLSFFSCSLLFPSSLSATFLLPFILLLFSSLSSFSTLSLFFILSVSFLLLSFFSCSLLFPSSLSASFSFLLLPVLFLSSFSSLPLSLSCPPSPFLSSLPSPYLVLPSPSFLLFPLLYLRLLFLSSLRFSSLSLSSLPLSFICVLPSPFHSSPVLFSFILYFSSPPLYLRSSFSFKLSFSLILSMYSPRPSQPPTGAPLLQDSPTRHLRPPTGRHLSSPSPDSPTPISAAHRALIIPIPSRPSQPPTGAPLLQILPRPSQPPTELSPTGAPLLQILPRPFSRPPELPSSRFSHAHLSAPSSLIPIPFTPISAAHRKSPSQPSRFSHAHPRPRVPHSLTPISAAHRSSPSPDSPTPISAAQELPFSRFSHRRPPELPFSRFSTPHLSRPPELPFSQDLPLPISPPISAAHRSSPSPDSPTPISAAHRRSPRPSQRPPELPFSRFSHAHLSRPPELPFSRFSHAHLSRPPELPFSRFSHAHLSRPPELPFSRFSHAHLSRHGAPLSRFSTPISAATELSPRFSHAHLSRPRSSPSPDSPTPISAAHRSSPSPDFHAHLSRPPELPSPDSPTPISAAHRSSPSPDSPTPSQPPTGAPLLQILPRPQPPHRSSPSPDSPTPISAAHRSSLLQILPRPSQPPTGAPLLQILPRPSQPPTGAPLLQILPRPSQRPPELPFSRFSHAHLSRPPAPPPDSPTPSQPPTGAPLLQPPISAGAPLLQILPRPSQPPTGALPLPFSHAHLSRPPELPFSRFSHAHLSRPPELPFSRFSHAHLSRPPELPFSRFSHAHLSRPPELPFSRFLPRPSQPPPELPFSRFSHAHLTAPGAPPSPDSPTPISAAHRRSPLLQIPRPSHRSSPSPDSPTPISAAHRSSPSPDSPTPISATVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QB76</accession>
    <name>A0A3R7QB76_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Polyadenylate-binding protein</fullName>
            <shortName evidence="9">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_008097</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds and protects the poly(A) tail of mRNA with or without an AU-rich element (ARE) and prevents mRNA deadenylation. Stimulates the translation of mRNAs to which it is bound during early development.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with dazl in an RNA-independent manner. The C-terminus can self-associate and also interact with the C-terminus of pabpc1, independently of RNA. RRM 1 and RRM 2 interact with both eif4g1 and paip1, and the C-terminus also interacts with paip1. Prior to oocyte maturation, found in a complex with dazl and pum2 proteins and spdy1 mRNA; pum2 dissociates from the complex during maturation. Interacts with the translation termination factor sup35/erf3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QB76"/>
    <dbReference type="STRING" id="6689.A0A3R7QB76"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.10:FF:000001">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000042">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000049">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="54"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="147"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="250"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="11">
        <location>
            <begin position="506"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00057784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00066197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT73432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="600" mass="66659" checksum="BBCF2A47DB374DC6" modified="2019-04-10" version="1">MITRRSLGYAYVNFQQPADAERALDTMNFDVMKGRPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKAMYDTFSAFGNILSCKVATDEAGNSKGYGFVHFETEEAARSAIQKVNGMLLNGKKVYVGKFIPRAEREKELGEKAKRFTNVYVKNFGDDLDDDKLYEIFSQFGKITSHRVMTNEDGKSKGFGFVAFEEPEAAEKACEEFNGKEMNGKQIYVGRAQKRGERQAELKKKFEMMKIERMNRYQGVNLYIKNLDDTIDDERLRKEFSNYGTITSAKVMTEDGRSKGFGFVCFSTPEEATRAVTEMNGRILVSKPLYVALAQRREDRKAHLASQYMQRVAGMRMQQMGQMFQPGGTSYFMPTMPQAQRFYSPQMAQIRATPRWPTQPTAQVRAGAQAASAFPMQAAPYRSAPRQAQPAPRNVRPITAAAATAQQQQIPNLMQAARPVAPNAGAVPPALSSAARASNYKYTTNMRNPPAVSGGGPASAAAVAPVVQPAVHIQGQEPLTPSMLASALPQEQKQMLGERLFPLIRDIYPELAGKITGMLLEIDNSDLLHMLEDRNSLKAKVEEAVAVLQAHQAKQQVVAVAVAAQKKEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QHB7</accession>
    <name>A0A3R7QHB7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase</fullName>
            <ecNumber evidence="11">2.4.2.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_014453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1-&gt;3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:56064"/>
            <dbReference type="Rhea" id="RHEA-COMP:14610"/>
            <dbReference type="Rhea" id="RHEA-COMP:14611"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57632"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:140575"/>
            <dbReference type="ChEBI" id="CHEBI:140576"/>
            <dbReference type="EC" id="2.4.2.42"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.42" evidence="11"/>
    <dbReference type="EMBL" id="QCYY01002808">
        <property type="protein sequence ID" value="ROT67456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QHB7"/>
    <dbReference type="OrthoDB" id="6238971at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140563">
        <property type="term" value="F:UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016266">
        <property type="term" value="P:protein O-linked glycosylation via N-acetyl-galactosamine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051993">
        <property type="entry name" value="Glycosyltransferase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46012">
        <property type="entry name" value="IP22168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46012:SF2">
        <property type="entry name" value="IP22168P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT67456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="693" mass="77871" checksum="4AD56E3660CD9068" modified="2019-04-10" version="1">MPLVIVACESKPTHEDPYISINDAADAADSDPHAALRLITSWERQQEQLTTMLKTLLYFSVAPVWRIIVLTDSRTTFDKVLGLTSLFPQEQRERLRLEHQHQWYPKYNSNISANWRPCAWAKQFLAEALPNEEAVVYVDTDLVFLGPPEEIWGLFEVMDAQQVVALSPEPKYSVETPRRKYAGRTGLNTGVMVANLTRQRSLLGGGLGTALLNSGLLNHAYRHDQDVLNHFLMDKPHLFKEVSARWNFMISSCHTAAPPCPDCKRLGVLILHGADVSFYRLLEGLFLVTYGVLSQLSLTEPPANVLARLRSRLAELETMKITDTACANMTMLAHSFTLGLTRLAARDRAILELSPSVKSPLVISVCESPNGYNSDDSLGLTDEDTDFTYTNRLRASWARQRSQMTAMFKTLLYFSKAPIWRIIVLTDTLDTFHRVVNITSAFPRRHKERLRFERREQWFPPGYTAIINNWRPCAWAKQFLAESLPEEDAVVFIDTDLIFLGPAEELWQVLESMTPPRAVALAPEPNYLTESPPRDYAGTAGINTGVMIANLTRLRQLPGGGLGSAIIAEGAIHPLPRHDQDALNHFLKPKPHLMLELTSRWNFLPSACMTRGSPCPDCVSSGILALHGADMTFFRFIDMMYANLLELNFDEAPAALLGRIQAQLNLLDSGRPIFPCSNYSEFNQAVTYGLARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QI63</accession>
    <name>A0A3R7QI63_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001561</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001200">
        <property type="protein sequence ID" value="ROT79697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QI63"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="498" mass="52106" checksum="5A87858CACB2711C" modified="2019-04-10" version="1">MSLPLPPHSPFPPRHATAPVLLPPSPSPRNSPSFPPPLPLPTSPPPPSPPRTQRTQQPQFSLPLPPPPRNSPVLPSPLPPRPAPILPPPPLPPRHATAPVLPPPYPPLPPLSTQQPQFSSPSPFPLPPSPRNSPGSLPAPPPPPFPPLATQQPRFSLPPSPFPPSPRNSPPPVLPPLPPSPLAPPPPPLATQQPSSPPPSPPPPATAPFPFPPSPPTASVLPPLPPFPPSRNAPILPPPLPLPPSPARPSPTLSPPPSTQQPNLPPPSPFPLATQQPRFSLPRSPPPSPFPPSPGNSPGSLSPLLSPLPSLATQQPQFSLPLPHPFPFPFPLPLPLPLPLPPRHATAPVLPPLPHLPPPPPPLATQQPRFSLPPPPSPPRHATAQFSLPPPLPPSPRNSPNSPSPSPFPPSPRNSPNSPSPPPSPLATPAPVLPPPPPSPPRHATAQFSLPLPPSLPRHATAPILPPPPLPPLATQTAPVLPPARGPQIAPWKKWHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QJS0</accession>
    <name>A0A3R7QJS0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pol</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002524">
        <property type="protein sequence ID" value="ROT69722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QJS0"/>
    <dbReference type="OrthoDB" id="6377262at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09276">
        <property type="entry name" value="Rnase_HI_RT_non_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052560">
        <property type="entry name" value="RdDP_mobile_element"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688">
        <property type="entry name" value="ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36688:SF2">
        <property type="entry name" value="ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="1">
        <location>
            <begin position="509"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="796" mass="90594" checksum="A71F20DF39481B07" modified="2019-04-10" version="1">MANNPNAEEKIKLLQWNILGFRAKLPLLTLALAEQRYDVVLLQETLLQTSITIPNYKGFHQFYSQDAPDLPSYLSSQQTRVHTPQRGVLDLSFVSTSLLPLTTWSLHPYLASDHFASTITVDLPRLQRRAPEPRWNFRRADWHEFSYLMEEWAETHVPAHDLEDQEKEIVAALHQAANQAIPKVGTSVFTHKNGWFYNDRVRELKHRLIVLKKKLKQHFSPSLLETFRAAHRLICKEIQEIRTNSWLEWCESLNAHTSLHDLWTKLNRVSGKHKKQPSHPQPLQIANDLIQSFQARSSNTQLPRSTLNRTQNLSHRRELSIHTAIALPSDLDVPFTLYEIKKAIKTSKDTAPGIDKISYSMLNHLGDHALMQITNLFTASLTSGRLPSQWKEANIHPIPKNTTPPSYRPISLQSPLGDSLRRILDTPQAPHRRVLPWHHEIHQSVTSFNLLPALLSRGIDAPHHGYAEPNPWEPPLAAFLINSLPRPKKNCSPNDLQNLRETISSIENDRDTTVIYTDGSVDPESGRAGGAFLCNDYVQASRLSNDSSILQAELFAIRSALTYALFCTKSTVCIFTDSLSAIHTLQNRAHLDNVYLATSTLFKLQQLTQQGKTVRIMWIPSHVGLEGNDRVDSAAKSSLHQTRLQPIKPSISQIKNRAKITAKQITLIQHQVWVQAGSPSATWYKTVTEYETITIPRSMSRKDAVIIHRLRLGYPCSWEIDERVPKECNYCQTVVSHPLTHYLLDCQALYHIRHHNFSDVPNRETSQRSTVAATYARTILDSEESFKTISAAPPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QLF9</accession>
    <name>A0A3R7QLF9_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TGF-beta family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_010494</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the TGF-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002331">
        <property type="protein sequence ID" value="ROT71204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QLF9"/>
    <dbReference type="OrthoDB" id="6350089at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008083">
        <property type="term" value="F:growth factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13756">
        <property type="entry name" value="TGF_beta_BMPs_GDFs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.90.10">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029034">
        <property type="entry name" value="Cystine-knot_cytokine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001839">
        <property type="entry name" value="TGF-b_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015615">
        <property type="entry name" value="TGF-beta-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11848:SF309">
        <property type="entry name" value="INHIBIN BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11848">
        <property type="entry name" value="TGF-BETA FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00019">
        <property type="entry name" value="TGF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00204">
        <property type="entry name" value="TGFB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57501">
        <property type="entry name" value="Cystine-knot cytokines"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51362">
        <property type="entry name" value="TGF_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0339">Growth factor</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="TGF-beta family profile" evidence="6">
        <location>
            <begin position="349"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT71204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="51088" checksum="4EC3FD89402E5F5D" modified="2019-04-10" version="1">MECLTTNDVKSVRTSAKVCEKNGTDFLKVKDNNVADPEASRKGGKEGECDRKRTCFAEEALLGRGRALLIVVILLLVLLLAFPLLFPLLSFPKSEPKVISESTDRTWRNEDYEEPAKRRGSPFHSKKEGKIWMRTERLLPTITLLYDRTTRPVTLYQPDTYEDSAAGQRWYFKAVQGHDGIADVEMFLHSSVQKFQLILKNPRGSTTVHHIALQPNAKTPSPSHLLLPATPVAELTQGLEAPSDCLVVNLSYHLNDWVARGSEFSILFETREANPPPDAGDSRDNTSFSQHLRHSLLQPVVTVLDHNTTFAVREDDGLEDALRETLAGRMAEVMARGTEAVATLPPLGRRRREASEECQMSMVSVSLDELGLNNVVYPTTVDMKFCKGSCHVIDDPAMFSTNALMRVKYKFLRSSASVPSPQCTPTFYKYLPFIIWQSGKLRKIGVSDLDATICGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QTH8</accession>
    <name>A0A3R7QTH8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative mucin-17-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_003643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001494">
        <property type="protein sequence ID" value="ROT77677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="832"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1540"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1637"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1844"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1929"/>
            <end position="1975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2088"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2356"/>
            <end position="2414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2432"/>
            <end position="2464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2622"/>
            <end position="2670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2713"/>
            <end position="2734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2914"/>
            <end position="2935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2956"/>
            <end position="2982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1640"/>
            <end position="1653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1659"/>
            <end position="1669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1683"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2090"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2108"/>
            <end position="2117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2140"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2357"/>
            <end position="2367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2369"/>
            <end position="2384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2403"/>
            <end position="2413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2448"/>
            <end position="2457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2651"/>
            <end position="2661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2713"/>
            <end position="2727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2922"/>
            <end position="2932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="3048" mass="321176" checksum="2667A16F76810022" modified="2019-04-10" version="1">MARLHTPLPVPRPASTPTPCATTRLHTPTPCATARLHIPPLCHDPAPHPTPCATTRLHTHSLCHDPPPHTPCATTHLHTPLPVPRLASTPTPCATTALHTPLPVPRPAPHSHSLCHDPPHTPLPCHDPPPHPSCARPASTPLPVPLHTHSLCHDLLHTLLLFHSPPPHPLPVPHIHSLCTTRLHIPLPVPRPRLHTPPLPMPRPASTPHSLCHGPPPHPFPVPRPASISHPVPRTRLHTHSPVPHPPPHPLPVPRPASTPHSLCHGLPPHPTPCATTPPPHPLHTQLPVPRPGACSTPTPHATTRLHTHSLCHGTCHPASTPHYPVPRPASTPHSLCHDPPPHPTPMPRPASTPTPVPRPASTPPLPVATTLPVPHTPLPVPRPASMPRPASTLPVLHTHSCATAASTPLPVPGPASTPHSCATARLHTTPCATTRLHTPTPCATAASTPHSLCHGPPPHPTPVPRPPHTPTPCATTRLTSHLCHGPPPHPTPCATTRLHTPLLCAHGPPPHPTPCATARLHIQLPVPRPAPHPLLCHGPPPTPTPCATARPTPNSLCHGPPSTPHSLCHGRLHIHSLCHGPPPQPHSLCHGPPPHHSLSLCHARLHTPVPRPASTPHPCATARLHTPLPVPRPASTPTPCATARLQHPTPLPHVPRPLPPTPHCPLCHDPPPHPTPLCHDSRLHTPLLCHGPPPHPLPVHGPPPHPTPCATTRLHTPLPVPRPPPHPTPCATDRLQHPTPCATARLHTPLPVPRPASTPHSLCHGPPPHPTPCATTRLHTPLSGSTPHVATALHTASLCHGPPPHPLLCHGSASTPHSLCHGPRANHTPLPVAHAPASTPHSCATSPPPHPTPCATARLTPAMPRPAATPCATTASTPTPVPRPASTPHSLCTARLTPHSLCHGLHSTLRPVATARLHTKLPVPRARLHIPVVPRPASTTHSCATHPXLCHARLHTPLPVPRPASTPHSLCHGPPHPTPCASTPHSLCHGRLTPHSLPASTPHPCATDPPPHPTPCATARAPHPTPCATTRLLTPLLCHDPPPHPLPVHDPPPHPTPCATAASTSHFLCHVRLHIPFPVPRPASTSTAGLHTHSCATTRLTLPVPRPASTPTPVLRPASTPHSLCHGPPPHPTPCATTRLHTPLPVPRPASTPHSLCHGPPPHTTPCATACLHTPLLCHDPLHTPLLCHDTPPCATARLHTPLPVPRPASTPHSLCHDPPPHPTLCATTRLPHPTPCHPHPTPCATPASTVHPLPVPRPPPVPPRSTCHVPPHTPLPVPLHTPLPVPRPLHTPLPVPRPASTPHLPVPRPASTPHSLCHGPPPPHSLCHDPPPHPSPVPRPASTPHSLCHGPPPHPTPCATARLHTHFLCHDPPPHPTPCATARFHTPLPVPRPPPHPTPCATARLHTPTPCATARLHTPLPVPRPASTPHSLCHGPPPPQLLCHDPPPHPTPCATARLHPTPCATARLHTHSLCHDRLHTPLLCHGPPPHPTPVPRPASTPHSLCHGRLHTPLLCHSHPTVPRPASTPHSLCTARLHTPLPVPRSRSPQHPLPVPRPASTPHSLCHGPPPHPTPCATARLHTPLPVPRPASTPHSLCHGPPPHPTPLCHDPPPHPTPCATARLHTPLPVATARLHTPLPVPRPVPPQPTPCARPASTPHTSCATARSTPIPVPRPAFHTPLPVPRPPPQTPLPVPRPASTTPLSVPRPASTPHSLCHGPPPHPTPCATARLHTTPCATSRLHIPLLSTSTPHSLCHGPPRHTLHTPLPVPRPASTPHSPVHDPLHTPLPCATAPPHPTPCATTRLHTPLSVPTTRLHTPLPVPRPASTPHSLCHGRLHIPLPVPRPASTSPLPVPRPASTPHSLCHGPPPHPTPCATPCHGPPHTPLPVLRPAPHPTPCATARLHTPLPVPRPASTPTPCATARLHTPLPVHGPPPHPHSSPCATASTPHSLFHGPPPPPHSLWPRPTSTPTPCATARLHTHSLCHGPPPHPTPCATARLHTPLPCATARLHTPPLCHGRLHTPPCATTRLHTPLPCATARLHTPLLCTTRSTPHSCATTPTPCPRPASTPHSLCHGRLHTPSLCHGPPVPRPPPHPLPVPRPASTPHSCATTRLHTPLPVHGPPPPHHSTPHSLCHGPPPHPTPVPRPPPHPTPCCHGPPPHPTPCATTRLHTPLPVPRPASTPHSLCHGPPPHPLLCHGPPPHPTPCATTRLHTPLPVPRPASTPHSLCHGPPPHPPCATARLHTHSLCHDPPPHPTPCATARLHTPLPVPRPASTPTPCATARLHTHSLCHGPPPHPTPCATGPPPHTPLPVPRPASTPHSLCHARLHTPLPVPRPASTPTPCATARLHTPLPVPRPVPHPTPCATTASSPHSCATTRLHTPLPVTRPASTPHSLCHGPPPHPTPVPRPASTSHFLCHVPPPHPLPVPRPASTPHSLCHDPPPHPTPVPRPASTPHSLCHDPPPHPTPCATARLPHPTPCATTRLHTPPLCHGPPPHPLHGRATALHTPLPVPRPASTPHSLCHGPPPHPTPCHGPPPHPTPCATARLHTPLPVPRPASTPTPCATARLHTHSLCHARLHTPTPCHGPLHTPLPVPRPASTPHSLCHGPPPHPTPCATARLHTPLPVPRPASTPTPCHTPHSLCHGPPPHPTPVPRPASNTHSLCHGPPPHTTPCATARLHTPTPCATAASTPHSLCHGPPPHPTPCATTPPPHPTPVPRPASTPHSLSTCHGLHTPLPVPRPASSPHSLCHDPPPHPTPCDTTRLHTPLPVPRPASTSHFLCHVPPPHPTSCATSRLHTPTPCATARLHTPTPCHDPPPHPTPCATARLHTPLPVPRPASTPHSLCHGPPPHPTPCTTRLHTPLPVPRPASTPHSLLPRPPPHTTPCATALHTHSLCHDPPPHPTPCATARSTTPLPVPRPPPHPTPCATARLHTHSLCHGPPPHPTPCATARLHTPLPVPRPASTPTPCATARQCHDPPPHPTLCATARLHTHSLCHGPPPHPTPCATSRLHTPLPVHARLHTPLPVPRPASTPCALFRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7QZ77</accession>
    <name>A0A3R7QZ77_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">C7M84_022380</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="12">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000542">
        <property type="protein sequence ID" value="ROT84431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7QZ77"/>
    <dbReference type="STRING" id="6689.A0A3R7QZ77"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROT84431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="343" mass="38295" checksum="BF7C74E925241D86" modified="2019-04-10" version="1">MPLPPSVSSSTRGQRRPQPTVPMDLPRRRRPLTYHRRRFPRALRSVSRPPGYPLPHLHSFSHELSGCKVFSRIDLVKAYHEIPIAEEDIPKTAVITPFGLFEFLRMPFGFRNAAQTFPRFINDVTRGLEGVFAYIDDILVASASEADYTRHRALFGRLQEAGVVINPAKCLFGAASFSFLGHTVTSQGINPVQEKVTAIRKFPKPATEKQLRKFLGVFNFYRRFVPKCAQLLKPLHALITPNKASRNAKIKWTPPTNEAFEACKEALASAALLNHPLPEAPLNIAINASDTAITAATVDRTFLSTWISCFGTPDTVTTDRGAHFESELCRQLIGHQSRTAPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7R0E1</accession>
    <name>A0A3R7R0E1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="22">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">C7M84_005619</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="25 26" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="25">Muscle</tissue>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 22">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 21">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 22">Membrane</location>
            <topology evidence="2 22">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 22">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="22"/>
    <dbReference type="EMBL" id="QCYY01000173">
        <property type="protein sequence ID" value="ROT85826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7R0E1"/>
    <dbReference type="STRING" id="6689.A0A3R7R0E1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090556">
        <property type="term" value="F:phosphatidylserine floppase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000021">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000055">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 20 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 21 22" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 20 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 22" id="KW-1278">Translocase</keyword>
    <keyword evidence="8 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 22" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="754"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="801"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="835"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="870"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="910"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="23">
        <location>
            <begin position="12"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="24">
        <location>
            <begin position="688"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="19">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
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        </ligand>
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        <location>
            <position position="369"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="546"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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            <position position="548"/>
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        <ligand>
            <name>ATP</name>
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        </ligand>
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    <feature type="binding site" evidence="20">
        <location>
            <position position="636"/>
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        <ligand>
            <name>ATP</name>
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        </ligand>
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        <location>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="662"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="665"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="666"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00004555"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
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            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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            <dbReference type="ARBA" id="ARBA00034036"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00051303"/>
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    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
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    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
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    </evidence>
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            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="ROT85826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1022" mass="115482" checksum="8932CCDDE395CDE9" modified="2019-04-10" version="1">MYKRHRADDEINKREIEVLRDGQWQWIKWRHVQVGDIVKVHNNRFFPADLIILASSEPQALCYVETANLDGETNLKIRQGLQETAHLLEARDLMNLSGKVECEAPNRFLYQFTGNLKMTSRQAVPLSPDQVLLRGAKLQNTNWVFGLVVYTGHETKLMKNSATSAPLKRSTVDKQTNNLIILLFFLLIVLCLIMAVCNSQWDANLHWYLSIDDLSVFNFGINFITFIILFNNLIPISLQVTLEVVRFIQAGFINNDVNMVYEENDIWAMARTSNLNEELGMIKYVLSDKTGTLTCNIMEFKRCTIGGKVYSMDDGSAQDLISLVETGGPGSAIVRQFLMMLAVCHTVIPDRDDSKPNGGIIYHAASPDERALVEGARELGFVFETRTPEHCIVDVLGTKEKYEILNVLEFTSQRKRMSVIVRTPQGQIKLYCKGADTVIYERLGDSQQFRDVTVRHLEEFAGEGLRTLCYAVADISPEFYEEWKNTFYKASTALQFRERKLEDAAQLIENNLTLLGATAIEDKLQDEVPETIAALLKAGIHVWVLTGDKQETAINIGHSCHLLTQGMPLIILNSDSLDETRESINRHVVEFGDQLKRENEAALIIDGKTLIYALTPDLRKDFLDLCISCKSVICCRVSPSQKAEVVELLTRETGSVTLAIGDGANDVAMIQKANVGVGIAGLEGLQAACASDYAIGQFRFLARLLFVHGAWNYSRLCKVILYSFYKNICLYVIELWWAAMSGWSGQVIFERWSIAMYNVLFTAAPPLVMGIFDRSCSAETRMKYPELYRESQSGSHFNWKVFVWWVWLALVHSVMVFVLPYLAMTQDVAWGHGLVGGYLMVGNMVYSYVVVTVCLKAGLETDAWTWVTHLAIWGSIASWFIFLLVYSNFWPVLPMAPDMCGIYLQVYSSPVFWFGLIMIPLACLLPDVCVKTIRNSVFKSLTEQVRESEISNKDVSKVLDTKHRLTETARLLKNVFRRTTTRVNLEVELAHGFAFSQEEHGVMGQSEVIRAYDTTQPKPGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SS62</accession>
    <name>A0A3R7SS62_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">C7M84_008986</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="13">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01002126">
        <property type="protein sequence ID" value="ROT72625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SS62"/>
    <dbReference type="STRING" id="6689.A0A3R7SS62"/>
    <dbReference type="OrthoDB" id="6381043at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.10.10:FF:000007">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="11">
        <location>
            <begin position="70"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="12">
        <location>
            <begin position="613"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="905"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="917"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROT72625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="942" mass="107235" checksum="39CD72A36D853F8C" modified="2019-04-10" version="1">MDFAEGEDILRRLLKEFPSLLPTKDRPLGRTDVLRHRIDLIPGTKPIYIPSYRIPHSRRAAFKEATDALLAQGIIEPSQSPWSAPMLLVPKKDGTLRPVIDYRRLNAATVPDRYPIPSIRTLLQEVGEGHAIFSSIDLAQGFLQVEMDPTSKDLTAFSTPHGHFAFTRMPFGLRNSPITFSRLMSLIMQGLIGDTAFLYLDDLLIASKDVAEHEYKLKLVFQRLADANLTINVKKCQFFRKQTEYLGHTVDSAGLRPNDKKVRDVQNFPVPTTATQVKSFLGLCGFYRPFIEKFGIIAEPLTRLLRKDTPFTWTGEQQQAFEALKQRLTEAPVLSFPDFNETFYLATDASSIGLGAALMQRHDGRYKPIAFASRKLNKAERNYSVTDLEALAVVWSLKHFREIILGYDIHVLTDHRPLKYILTDSRHAKGRQARWIDTLLEFNPKIDYTPGSTNKVADALSRNVSVNHLSVLSPTELQAKQRDDPLYAEIIAHLEDNTKPPPTNRNLPIEEFYLRDGLLFRKSAPKKLRGSKQRRTYHQLVIPEVLVPTVLKLLHDSHTSGHQGIFKTLQLARSRYYFPRLGPRVVEHVKSCQICPLYKGHTVAPAPALTYDVPERPFVRVSMDILSGFTPTENRNRYLLVMIDSFSRYTELAPIPDKSAQTVARAFLSHVICRHGAPEQLMCDNGTEFTNQVLKGLCKLLNIDLVHILPYRPQANGLVERLNRTILNVLRTSINTQDSEWDLWIPITQAAINSTFHSSLGDIPNYVVYGDDQRLPYELLQQRPSPVYGEDYAKIVIARKQEAYRIAREHLRVERDRIIAQQHKLARRKKIAEGVLVFHRVTDKSFPMPKLAPDFEGPLRVLKVRHNKALCQNLTTCSQTWYHFDTLKLASTHYEDEYNRQRSLTSLTPTDIAPDSTPATSMTLSSPESDALSLPQTPSSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7SSH0</accession>
    <name>A0A3R7SSH0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002080">
        <property type="protein sequence ID" value="ROT73023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7SSH0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="184" mass="19975" checksum="EDE0A01B01F9C6EB" modified="2019-04-10" version="1">MGRDKPQGGKRKGLLKSVKEAHLDARNSREDEKNEEPLNGERWNSGRSKSSAIGSGQKRTDFGENANAEKRAGNIGADVTLVVKHLFVRRCCLDPSARPPCRPRYLRRDSASTPAPVGTQPSPSEVAESRTTACQRLNPEGNPPDCRLDGEVQARQGVACPFSNGGATEGRALCCTRPAVHHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423S9D1</accession>
    <name>A0A423S9D1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative DIS3-like exonuclease 2 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_021600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004547">
        <property type="protein sequence ID" value="ROT60805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423S9D1"/>
    <dbReference type="STRING" id="6689.A0A423S9D1"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008266">
        <property type="term" value="F:poly(U) RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010587">
        <property type="term" value="P:miRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000003">
        <property type="entry name" value="DIS3-like exonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNB" evidence="10">
        <location>
            <begin position="352"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT60805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="536" mass="61353" checksum="12DAA3836F29BE24" modified="2019-05-08" version="1">MDIYIGGVRDRNAALHGDVVVVEIKPIDQWKVLYDQLDQYLDHHNAGNKKKRRRRRGKPSKIQDTSHLKEVCTASQGGTQEKPDESCKDDNQELVIVLQTEPVKVADELVLLSCPTFEECKQVPQEDDFDNFKEGVKGVVVPPDQLSECDFTDDESGCSEILDYSQMREDQSFMQAQWEAYKKEFNQKQREESQEYHKKSEAEKEPRDAGILVKKCFETLDIKQEIAVGFPEGFVKEENLDDNKNPNYALFSPTDNRVPRMKIPMFQCPPDFMARNQDYLARIFLARITQWKEPKFALGELVRDVGAVGDIEAETEAFLQEYGIDHREFPEEVTKHLPQLPWSIPAEEIAARTDLRNQCIFTIDPSTARDLDDAVSCVPLKNGNFRVGVHIADVSYFIPEQSPLDIMASQRATSIYLTEKVIPMLPEVLCQNLCSLNPGEDRLAVSVIWELTPDGKILGEWFGRTVIHSCVKLAYEHAQSMIEEPHRQWTKEEIPEVRHSSVIWSKTAAWNLFSSYQYIFSRTPSPLSSSPTPTYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SBF8</accession>
    <name>A0A423SBF8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_020661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004119">
        <property type="protein sequence ID" value="ROT61542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SBF8"/>
    <dbReference type="STRING" id="6689.A0A423SBF8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="507"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT61542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="889" mass="101986" checksum="4122026A3C45D857" modified="2019-05-08" version="1">MANRLLIPVSSGVRYTVTTFLRVSHIITHNQSHIHITTFTTLLFTSPHSHHQIFTTFFLTITHISPNILDHHTFLTSTTTYHHILLLPSHISPHSSDHHTFLTSITTYHHILLDHHHIPSSPTYPFLDHHHIPHNHQHSFFDHHHISSDHPPFLTQSPHITTFFSTIPHSSHQSPHIHHILLYHPPHITTFFSTITTFLTSITTLSPHIPHSSRPSPHSHINHHISPTFFSTITTYAPHSLLPSPISPHSSQPSPHITTYHTFTTYSPHSSRPITINYHHILLAITTFLTSITTYHHILNLTHHTYQPIPSSPSPINITTFFSTITTYTTFFSTITTFHSQINHISPHFFSTITTFLTINHHISPHSSLPSPHIPPSSHSPHSSHQSPHILPSHSSRHHTYPHINQPHITTFFSPTTAPHSSHHHHISPHSSRPSSSHQSPQYPHSSRPFTTFLTSSHIPPSPTFTSITKYHHILSTITHSSHQSTTLPTLHSQPSPIPHINHHISPHSSRPSPHSSHQSPIFHHHHSHHSPHSPSLSSHSSPHSNHHISPHSSNHHTFSHQSPHITTLSRTSPHSSTINHIHTHHHISPHSSPITTITFTFFSTITTFLTHTTFSLPSPHYSHHHHIPSRPSPHSTTFFTTSPHITTLFLEHHHHFTTIPHHIFHDITTTSPHFITTIHHISPHILDHQPYHHIPHNQSPHIHTFFLDHTHISHTFFLTITTYNFFSTITTYHHIPHNHHTNHQHSSAHHIHQFLDITTHSSIHHNISHFLLDHHTFTHSSRHSPHTPHSSHHHITYPHSSQPSHNIITTFFSTIITYHHTFFPTITTISPHFSRPHHHTYHHILLTNQSPHITTFFSTITTYHHILTTITTYHHILLDHHHISPHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SE40</accession>
    <name>A0A423SE40_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003669">
        <property type="protein sequence ID" value="ROT62477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SE40"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="426" mass="47104" checksum="27BC7FC22B59086A" modified="2019-05-08" version="1">MSVGNKPAPLPFRQLTLLKGVGSISKSKAITWRSSRDPKAQDEPDPSSRATAPEPEAATRNQKPTVKQRRSPCHPLLLLLPLAIPSLQPSPPPSYSPLRLASPPSPSLHPSILSSYPSFLSHLSPLLSLSTSLSFTPLSLAPSHTSYLSILSYLSSHPSFSSPTLPSRSRLSSSSLLFPFPSYHPSLSSSHSLSHLTRRTRFPPFPSISRISSHHIFSLPLPIIDSFPSLFSSFPSSHLIRPPLVLLHHKPFPLSSLPTSLSVYPPLSPRFHPILSYLSFPSHPPPLSLPTSLSFPLFLSPSLPFHLTLSHPLVSFSSPPLPIALVSPNPFPPRRERDLDSRHEAAHLFWLLTKPKTPTRVQRSFPPQRAQITRIFLGPPDTYAHAHPGPAWATKCAAQRRDSTALHVRVQRNKYRTMPRTKSYMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFM0</accession>
    <name>A0A423SFM0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative serine proteinase stubble</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_019129</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003507">
        <property type="protein sequence ID" value="ROT62998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFM0"/>
    <dbReference type="STRING" id="6689.A0A423SFM0"/>
    <dbReference type="OrthoDB" id="414661at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000006">
        <property type="entry name" value="Serine proteinase stubble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24253:SF145">
        <property type="entry name" value="SERINE PROTEASE FILZIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24253">
        <property type="entry name" value="TRANSMEMBRANE PROTEASE SERINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S1" evidence="7">
        <location>
            <begin position="784"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="81"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="467"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="563"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="646"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="467"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="505"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="563"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="646"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="673"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="721"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT62998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1026" mass="109836" checksum="FA5A079451E29525" modified="2019-05-08" version="1">MEVRSSSGHRRLQIEPRQCHGADGEPGVCMFNFECYQRGGHVVGTCIDGFLFGACCDLPEGATLPTETPVAAVIPEVPAEVDLTGSGPESVAEEEATSGGAASSSGGAAGGAVTQGATTTEVIVPGIVNVRVPEASGPEDETSESGGPGETSTEMQVEATSANSEDVHETDGMEDVNTAGPTEPSANSDDEGAMATADDSANGGDSMDVEDSTVKSTDVTEADEVSNQMESSIDDQGALLTSVSLLDATPPATEPSSKFHSDVETGIPDVLAEGGVITFTIVESAAPTSEGPGADAEENTEQVIMMTLPDGQDGFATHEIVNFDVTDALNDGEENTENPGLMLSPSDELYFEPKPTSHRPYVRPASGQKTSTSDPLLAWEDEATPPPVDVSAQTIYVLSQTTDEAEVGILTTDKPPEPTVVPDSLERTSTEAISLLTPQTTESTTEPILIWTLSPQPSILDARPPTSVISQVESHTSATMPKPASKPAADEEETQGDIPQPAAPVTTSKPPQSTEKTPASEEGTPDLEDPLAFWTTTRPKRPRPRPKPTTTDEPLLIWTTTKKPPQATTTASSASVSVTPEDEDLFPDPDIPLQPAIIPGDILQHITGDLLHGAQNQTTADATTTTPWASSTYSIATVKYEDPSVNTLTDAPQQSTTMADEVTLTSTSQVDATTTTTTTTTTTRPKTTTSRPTTITTTTERTTQATTTKKRRPTMTTTRRTTTRRPTTKNPTRRPPSRRPSTRKPSTQRPTTRRTTAKPPRTTTKGESTTRPTTDEPISPIDQIVNGERADFAEWPWQALIKESTWLGIFTKNKCGGVLLNRKYVLTAAHCQPGFLASLIVVLGEFDLSDDYEPKKTVQRNVKRVVVHRGYVAKTFDNDLALLEMERPVTFDEHIVPICMPQGDENFTGMIGFVTGWGRLSYGGPVPTQLNEVAVPIIKNNDCQKWFLEAGHIKNIKPEFFCAGYKEGKKDSCEGDSGGPLSVQGEDGRWVLAGTVSHGIKCAYPNLPGVYMKMTYYKPWIESIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SFQ9</accession>
    <name>A0A423SFQ9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative retinol dehydrogenase 13-like isoform X3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_019078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003502">
        <property type="protein sequence ID" value="ROT63050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SFQ9"/>
    <dbReference type="STRING" id="6689.A0A423SFQ9"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="285"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT63050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="359" mass="39002" checksum="5BBF82CB56CC3B36" modified="2019-05-08" version="1">MGWKPPRYFLGLTAFGSFAGGIVLFKEVLGGGNYQGDEGLEGKTVIITGANTGIGKETATEMARRGARVIMACRDMEKCKEARKEVALATFNKSIYCQECDLASQESIRKFAERIQKKEDQVNILINNAGVMRCKKSFTEEGIELQLGTNHMGHFLLTNLLLDKLKASAPSRIINVSSVAHMRGSIKFDDLNSEKNYDEGDAYAQSKLANILFTRELADRLQGTGVTCNAVHPGIVLTELEPTPPPPITPTPLMESRVKTIPSRPLPPSPFLSLLILPPLLSPSPPPPPFPSSLSPPPFLTTSPFPPSSNRRRAPLETPNPSRPRGHGEDKAYLLSPDPRPGTDKAAGGARWIIAVLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLU2</accession>
    <name>A0A423SLU2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transcription factor hamlet-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_016881</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003131">
        <property type="protein sequence ID" value="ROT65160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLU2"/>
    <dbReference type="OrthoDB" id="9368434at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000112">
        <property type="entry name" value="Mds1 and evi1 complex locus protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000159">
        <property type="entry name" value="Mds1 and evi1 complex locus protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000929">
        <property type="entry name" value="Uncharacterized protein, isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="280"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="328"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="389"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="209"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="349"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT65160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="418" mass="45005" checksum="29DE370B1ECBF43B" modified="2019-05-08" version="1">MQSAPSGGFSLYPRAPVSVVPPALLTYQMLASQPPRDPPPTYPLLHSSFFLPIHHGRGPALSPHSPKEGEEKAALPPSPRAQATGDSARSSPASSPRLPATCASLKRRLEGDDGAVTSSHSDGEAPGATSDDRFRSEKPESQAEAVRPKPRQDHPFLRISDLLKDSPSTTSTPPTTPPQRVHGGELPPSPPLPPLRLAVPPASLPPSLPRGRSASTSSRATLPAAPRHYADLVRPYSDLLAPHATRSAKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKEKPFKCPLCDRCFGQQTNLDRHLKKHEEEGPNPPDSPEASEIPDSSVASMSSSSAADLDAERLDVDTDEEIKLEITAVPASLVAGSCGADDSAPDQLLAAAPDEPPAKRSRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2023-02-22" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SLX3</accession>
    <name>A0A423SLX3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016873</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003130">
        <property type="protein sequence ID" value="ROT65171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SLX3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="457" mass="49416" checksum="940F3A1B80D0AD99" modified="2019-05-08" version="1">MEEPPTLVFSSPPVSSLPLPPASSLPLPSISSLPLPLPPPSISILSPPSFSLLPPPSLSLLSPPSLSLLSPLSLSLLPPYISLFFRSHFLPLFPFLFFLRNFIPLLIFTPPPLPPSSLPRLPRLLPSLPSLLLCFSLPFPSPPPSSPPPSPLPSLSLFVPPPQSLLFPRFLPFSLPFFLSLFPISNPPFTRPFSRPFSFLSTSLPLPLPFLHPSLPFPSPPPPSSPSPPPLHYFLPFPLPSSFLFPSLPSSLPFLHSPPFLPLPLPSFPFPFPHLSFLFLPPPLPPPSTSLPFLSPTLYAPSPLQPPPPPHLGNIALKVSTLFPPPLSFPFSIDLLSAFLSLFSLYYLSISVLSLYVSYLLFSLPLSPPSTLSPPSPFPPSLSLPPLPLPPPPLTLLPLPPSFPSFPPSLPLPPPPPFPPSLPSLLPPSLPPSLPLSLPSLQYDPHLFSGRRHSTPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SPL3</accession>
    <name>A0A423SPL3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative tripartite motif-containing 13-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_015905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002990">
        <property type="protein sequence ID" value="ROT66137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SPL3"/>
    <dbReference type="OrthoDB" id="6382793at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047153">
        <property type="entry name" value="TRIM45/56/19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462">
        <property type="entry name" value="BONUS, ISOFORM C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR25462:SF296">
        <property type="entry name" value="MEIOTIC P26, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="8"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="167"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT66137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="248" mass="27866" checksum="8443D850C450E05E" modified="2019-05-08" version="1">MDEEGLSCIICEEQYSDRRNPRALNCGHSFCTPCLNQLFMQNFRTCPECRAVIRNASVKTIPINYSLLRLVRPQGAQASKPSPKAVKEPNGGKCQAHGSIMFFWCVKCCTWVCRDCLVLDHPDPPRGSCVIKAPKEAAADMVQADNQKVKVMIADIEGIIKVMESASLHVEQQKKQSENRITALKQEMSELEATVQSYTAKQQEVTKNVTDMKTWIRKLQESLVQTAKATTPEDAKNILSDVSLQKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SQX2</accession>
    <name>A0A423SQX2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">C7M84_015363</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="19">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the G-protein coupled receptor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002917">
        <property type="protein sequence ID" value="ROT66564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SQX2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007601">
        <property type="term" value="P:visual perception"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050125">
        <property type="entry name" value="GPCR_opsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000276">
        <property type="entry name" value="GPCR_Rhodpsn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017452">
        <property type="entry name" value="GPCR_Rhodpsn_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001391">
        <property type="entry name" value="Opsin_lateye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027430">
        <property type="entry name" value="Retinal_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24240">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00001">
        <property type="entry name" value="7tm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00237">
        <property type="entry name" value="GPCRRHODOPSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00578">
        <property type="entry name" value="OPSINLTRLEYE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00237">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50262">
        <property type="entry name" value="G_PROTEIN_RECEP_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00238">
        <property type="entry name" value="OPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10 15" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="12 15" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="5" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13 15" id="KW-0807">Transducer</keyword>
    <keyword evidence="6 15 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0844">Vision</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 1 profile" evidence="18">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="256"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROT66564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="274" mass="30546" checksum="7021D40CB14F1E54" modified="2019-05-08" version="1">MTPPLLVNAYWGTWVLGAFFCEIYAFFGSFFGCVSIWSMVFITADRYNVIVKGVSAEPLTSGGAMLRIAGTWLFTLAWCLPPFFGWNRYVPEGNMLACGTDYLTETELSRSYLYIYSVWVYLFPLAYIIYSYTFIVKAVAAHEKGMREQAKKMGVKSLRSEEAQKTSAECRLCKVALMTVTLWFVAWTPYFVINWGGMFNKPIVTPLFSIWGSVFAKANAVYNPIVYAISHPKYRAALEKKLPCLACNTEGRDGGASDAGSTATAQSTEKAESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SSV4</accession>
    <name>A0A423SSV4_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_014637</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002824">
        <property type="protein sequence ID" value="ROT67284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SSV4"/>
    <dbReference type="OrthoDB" id="336321at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT67284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="228" mass="25405" checksum="1E6F1502AF8FE2AF" modified="2019-05-08" version="1">MAGLSGLVADYGSSSDGEQDEDNLAEELQNRMEEKKSTNFFESPPDETNNAKKSKKKPDLEEASLAKPEILENPLRGNAIPSPFAENTSASVFFNPFHKAQEDKKLVLEKHVKMTDNPKDVMEINGKKICWNYRKGRCKFGHKCKFAHDSDISQPLDPKEAQTSSTNPSSLSQTTPGTQVLVEEPASDDTLSKKKKRPGLSDGLVPGKKVQKLYRSQQAKESPWLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SW48</accession>
    <name>A0A423SW48_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AmphiDkk3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_013365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dickkopf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002662">
        <property type="protein sequence ID" value="ROT68474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SW48"/>
    <dbReference type="OrthoDB" id="4321958at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039706">
        <property type="term" value="F:co-receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048019">
        <property type="term" value="F:receptor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090090">
        <property type="term" value="P:negative regulation of canonical Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.80.10">
        <property type="entry name" value="Lipase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006796">
        <property type="entry name" value="Dickkopf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039863">
        <property type="entry name" value="DKK1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12113:SF31">
        <property type="entry name" value="DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12113">
        <property type="entry name" value="DICKKOPF3-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04706">
        <property type="entry name" value="Dickkopf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="domain" description="Dickkopf N-terminal cysteine-rich" evidence="8">
        <location>
            <begin position="133"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT68474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="279" mass="30879" checksum="3DA899BE1FEB12AA" modified="2019-05-08" version="1">MSVDAVRGRCAAHVLVRRHEGHELVPGRRLLSRVFAHKAALARTKLVHGVVEAALRDVALVAQRHTPLTHLLSMATGAAHPCSTIPLLAAPGALTPTLDALLAQPNMQAYPPSHMASRRHSYLMISFVLQRLCTNDRVCGRGQFCDQHYGVCRDHVTEGHECRRDAMCEGGYACMFGLCQKRIKRGREGARCRKERDCGAGMCCARRHGEQVCQRRVPLGHKCYVPEGGLDYSMNQLCPCESGLVCKYTAQQPPSRHQLMALMSAYEDMRCAAPSHRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZ70</accession>
    <name>A0A423SZ70_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arrestin1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">C7M84_012502</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="4">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002583">
        <property type="protein sequence ID" value="ROT69308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZ70"/>
    <dbReference type="STRING" id="6689.A0A423SZ70"/>
    <dbReference type="OrthoDB" id="298939at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002031">
        <property type="term" value="P:G protein-coupled receptor internalization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016060">
        <property type="term" value="P:negative regulation of phospholipase C-activating phototransduction signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045494">
        <property type="term" value="P:photoreceptor cell maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007608">
        <property type="term" value="P:sensory perception of smell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.840:FF:000002">
        <property type="entry name" value="Arrestin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000698">
        <property type="entry name" value="Arrestin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017864">
        <property type="entry name" value="Arrestin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014753">
        <property type="entry name" value="Arrestin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792">
        <property type="entry name" value="ARRESTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11792:SF16">
        <property type="entry name" value="PHOSRESTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00309">
        <property type="entry name" value="ARRESTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00295">
        <property type="entry name" value="ARRESTINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="228"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROT69308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="415" mass="46293" checksum="127EBC6AC0106D67" modified="2019-05-08" version="1">MSRGRSYKDPGTVRLRKDSVIPISPRVTVSSAAFRCSSRMVVQFKVFKKAAPNGKLTIYLGRRDFVDHVSAVDPVDGVLVVDPSYLQGRKVFGQLVCSFRYGREDDEVMGLNFQKDLFLASEQIYPPKDVEPTKLQERLIKKLGGNAYPFTFKMPEQAPPSVTIQPGREDEGKPCGVEYYIKVYVGENEDDRSHKRSTIQLNIRRIQFAPSKTGRQPCTIVRKDFMLSPGELELEVTLDKQLYYHGEKIAINVTIKNNSNKTVKKIKAAVQQSVDICLFSGGQFKSTVASVETQEGCPVSPGSALQKCMYLTPVLSSNMDRRGIALDGHLKNIHTNLASSTLMANPENRDMFGMVISYTAKVKLYLGAMGGEVTAELPFVLMHPKPDLRRMMRADSQAQVESFRSESIAASVDMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423SZK0</accession>
    <name>A0A423SZK0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_012097</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002532">
        <property type="protein sequence ID" value="ROT69690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423SZK0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT69690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="510" mass="54418" checksum="73C70695F49E97F4" modified="2019-05-08" version="1">MYPFFIILFLSFFLLFLFSNPHFTFHNYLLHLLFSSFFLPPPAPLPPFSVLPFSSSLISLILFSCSFPSSFSSSSSPPNPNPPPPSLSSSLPSPPPPPPPLLLLLLLLISSLLPPLASRPPPLTFPSVQPPPKHLLLTCTRTGPSAPSPSSPSPSPPLPISLSPLSSPSPPLPPSPSLPFSFVSLASPSTAQLTCSLFLPLGPFSLSFPPSPTFLPSLLSPFPINQYLPSFLSILSLSSLLPYSLHLLHIFFSIPPSLSTLPSSPLALLFLPFPLPTSFSPSLHLSLPSFPPIPPSISSSHLPSSNHPFPTRLLNLNYPFPPSLPPFPSIPPFFPPPTFSPSLPPFPPLLPPPTHLPSLPPFAPSPHLPHLISPSLPSFPPPSLPSASSLFTPPCTYNRRGVNGSQIIRTVLDLRTEARAAIGSVERGSVVAVFLAWCCVRWARADQTKRAIGKRQPALIPFFPAPKAALAPPAGAAKGSRLRHVPSPHGSRWLMGGFGLSCARGSGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T2L2</accession>
    <name>A0A423T2L2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_010929</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002387">
        <property type="protein sequence ID" value="ROT70772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T2L2"/>
    <dbReference type="STRING" id="6689.A0A423T2L2"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14348">
        <property type="entry name" value="UBA_p47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.210:FF:000001">
        <property type="entry name" value="NSFL1 (P97) cofactor (P47)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="10">
        <location>
            <begin position="176"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="9">
        <location>
            <begin position="305"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="41"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="132"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT70772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="384" mass="41560" checksum="B7E9B04A64F3E2AA" modified="2019-05-08" version="1">MADKDKEGLVSQFTLISGVDAERAKFYLESAAWSLESALSSFYEEADEEGPSEALGDRPEAEGAPSTPQRPSSQPTPLARLNMVDSDSSDEESGQAFYAGGSEHSGQQVLGPPKKKADMIAKLFKSAKEHGAEVIEGGRESKKPKRITFGGTGYRLGETENDTEVIPDQRDHDERPRDVSLKMWRTGFTVDDGPLRAYEDPENAEFLNSIRRSEVPLELIREARGGEVYINMSDHRHEEYVPPKASLKAFSGSGHTLGSPAPSVVGQQAHPAGAVGGASGSTVISGPSDPKSAEKKAQDDLKVDNGQPTTNIQVRLPDGSRFVIKLNHSHTVGDIRHFIVTARPAFQAVDFALMTTFPHAELTNLSQNVVEAKLLNSALVVKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T303</accession>
    <name>A0A423T303_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aspartyl/asparaginy/proline hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010873</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartyl/asparaginyl beta-hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002380">
        <property type="protein sequence ID" value="ROT70854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T303"/>
    <dbReference type="STRING" id="6689.A0A423T303"/>
    <dbReference type="OrthoDB" id="438431at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062101">
        <property type="term" value="F:peptidyl-aspartic acid 3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039038">
        <property type="entry name" value="ASPH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12366:SF29">
        <property type="entry name" value="ASPARTYL BETA-HYDROXYLASE, ISOFORM L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12366">
        <property type="entry name" value="ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aspartyl/asparaginy/proline hydroxylase" evidence="2">
        <location>
            <begin position="256"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT70854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="423" mass="48199" checksum="2F96E5E78E60CDE5" modified="2019-05-08" version="1">MHPTSTLGLTSLPNPGKALNSFGALLHRVPQSARALYGRACSLDRLAEVERSNSRLEQAIATYRSVIDMADEHPDQVPLPLLRLAAEKCIERMRFRGFMGKAVRVQQRLLQRFPDDISLRNQMGVTFLLMNQPAAAKDVFKEVLEKWPEDGFAQVHYGFVLKTTYNNNTGGIEYMQKGISSGAEGTQDGRFYFHLGDALQREGKTEEAYKLYDIGVEKGLFLSRYQRSLYNVDRLRSQPLWSQEETSYQEFFRKLEQNWLIIRKEGLEALALPPQDGFRPEAENLQDTGDWKQYEIFSRGRKITANCVKTPQTCALVESFKPAAGCKRGQVKFSVMYPGTHVHAHTGPTNCRLRAHLGLLVPEGLHLRVGETNQSWAEGRVIVFDDSWEHEVWHEGDSPRLILIVDVWHPELTEEERLSLSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3R1</accession>
    <name>A0A423T3R1_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Peroxisomal membrane protein PEX16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">C7M84_010613</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="5">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peroxin-16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002345">
        <property type="protein sequence ID" value="ROT71094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3R1"/>
    <dbReference type="STRING" id="6689.A0A423T3R1"/>
    <dbReference type="OrthoDB" id="2021143at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013919">
        <property type="entry name" value="Pex16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13299:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08610">
        <property type="entry name" value="Pex16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROT71094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="333" mass="38295" checksum="01529178EB0F09CA" modified="2019-05-08" version="1">MASKMQDCYQWFLQYKKWVMNNPQGASEMESVVKWGSYFLAGRFKDSTLLCEIVYSGSRLFEMFNDFLVRGTLPKLTSKQGDKLKVFLTILEYVEVLVEVAAVQLWGEMGRWAVVAIIQLTKCIGRFLLVLKYKTSLVSSPPIKPLDRRAVMQTRQQMYNNQGSVPESFRLPHSGRVMRTLAGAPPTHQRTFNPPQPPSNNENETVAQKMLSPKQLTAEALHILRPIGHLTSMYLFGKQSWAPWVLALGMDITSLNLYNESMLSAAERSELARRRISLLYYLVRSPAFHTVTHKRIKYFLTTVGNRVPLARTVCQPLLEYIPEWQKIYAYTWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T3X3</accession>
    <name>A0A423T3X3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative 36.4 kDa proline-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_010474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002329">
        <property type="protein sequence ID" value="ROT71222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T3X3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019095840" evidence="2">
        <location>
            <begin position="20"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT71222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="567" mass="60144" checksum="43CFD09811A6F883" modified="2019-05-08" version="1">MKLMLHVVISLLLHQILKSLSSDTWYCSGSPPGRPPWLLPPVRAPPPGRPPWLLPPVRAPPPGRPPWLLPPVRAPPPGRPPWLLPPVRAPPPGRPPWLLPPVRAPPPGRPPWLLPPVRAPPGRPPWLLPVRAPPPGRPVARSYHQFGLLLLATSVAPSTSSGSSSWATSVAPSTSSAPPPGRPPAPSTSGSSWATSVAPPSSDSSWATSVAPSSSDSSWATSVAPSSSGSSWATSVSFQFGLLLGDLRSSFQFGLLLGDLRGSFQFGLLLGLRGSFQFGLLLGYNKYEADVARGHIEEPFKLLGLRGFHFGLLLGDLRGSFQFGLLLLGDLRGSFHSAPPGRPPWLLHQFGLLLLGDLRGSFHQFGLLPLGDLRGSFHQFGLLLLGDLRGSFHQFGLLLLGDLRGSFHQFGLLLLGDLRGSFHQFGLLLLGDLRGSFQFGLLLLGDLRGSFVRALLLGDRGFQFGLLLGDLLAPVRAPPGTSVAPSSSGSSWATSVAPSSSGSSWATSVAPSSSGSSWATSVAPSRLLLGDLRGSFQFGLLLGDLRGSFQFGLLLATTSVLPLSRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423T9F2</accession>
    <name>A0A423T9F2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_008511</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="QCYY01002073">
        <property type="protein sequence ID" value="ROT73068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423T9F2"/>
    <dbReference type="STRING" id="6689.A0A423T9F2"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT73068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="366" mass="41851" checksum="489368682D3C29B2" modified="2019-05-08" version="1">MFLLPVSRSLATQVLKPVALRQFYSLGKMLWPREGGKFISERAKDVQVIPEGVEKVAAMLSESVKEGKMNLKEFLQNDILPVDKGLTEEQLLNWTFLVDTLNFNFWTPDGEPKYTVKDKGRKRTGYMAMVAAINRAIDEGKKIYDPNYYSKLTIDDIKHIFRSETESTMPLFNERVRVLGEVGKKLIEEYDGTFLNVLKKADCSALKLVDIVTSEFECFRDVAKYEGQEVAMFKRAQILASDIWVLFRGQGLGAFTDIDKLTIFADYRVPQAMAHFGVLKYSPSLEEKLKKQHVFQSGEREEVEIRGCSIHAAELIVERIKDLLSQSGCSASINSAKVDFFLWDYRLMNAAALESVPYHRVRCIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TA84</accession>
    <name>A0A423TA84_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative glycine receptor subunit alpha-4 isoform X2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_008078</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002026">
        <property type="protein sequence ID" value="ROT73413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TA84"/>
    <dbReference type="OrthoDB" id="6379185at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018000">
        <property type="entry name" value="Neurotransmitter_ion_chnl_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001759">
        <property type="entry name" value="PTX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00354">
        <property type="entry name" value="Pentaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00159">
        <property type="entry name" value="PTX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00236">
        <property type="entry name" value="NEUROTR_ION_CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51828">
        <property type="entry name" value="PTX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019442792" evidence="9">
        <location>
            <begin position="24"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="742"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="786"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="819"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="872"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="domain" description="Pentraxin (PTX)" evidence="10">
        <location>
            <begin position="44"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="488"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="507"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT73413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="896" mass="103017" checksum="717D0D74E99CCC25" modified="2019-05-08" version="1">MFAGSPCVFGVLLLACVFQSTVAQESSAAKPMVWKWSKATKIEVSHVKFQTGDFDTIDSYLDNEAEFPDLTQFTLCVHIKYLHVAENNTLLSYYADGRDNELTIFTNSLDAETLQLFCCGNRVRNYMHYPIRLYTWEHLCISVNLRKKLITLVLNNDVKEYEVHEIEVQGQETEPLIVRGGGRLVLGQDLDSEDGGFSIEQVLSCEIADFAIYNTILTMDEIRSFMACRNRIPYEPIIYVDQAMTTLRAVGETEITTILEEKICAKSSGYNLLFPERVGFTESVSWCEMLKGTLVLPANKKENEEIYDKFFPFRDVCTDSWRTFYYFGTTRNVTTDKWFNYRDGSPILWENFDVQWNMMSSDYECAGVGNHLFMYTWFAIPCASSMCSACNFTAAPKLRIRGLCETSILDRSYYLNDYYNRRPLFDGETHSRIQWSNRSWELTSRRHRDLSAQMITKNPKLYPLGLQTWIISGDKCTQDTIELLMTPCGSDEYTCSTGSCIRKTSRCDLAIDCPDQSDELNCDVVNVPSGYSSALPPPKITEDPLDFRFSLRIITIREFNLVSFTLVVDAVISIKWRDSRLTFRNLRGNYQVNKVRDMNQLWTPKFLVRDGSRSAADLQVRSEAVYVVKEDAPVPDDITIISEDDRYSGTNNTLVLETESTMEFTCQFQLQMYPVDRQRCYLLFTIPGFSKDFGVLVKDGEGVIFEGTRRLLEYEMVKEVVAVEEEGKNTYVKIRLDFKNLYGYYIGNTFVPSLFLVVIVYLTFYFDTDDFEVRSLTRFYGQQNRIMVSLMSLLVLATFFTETSASIPRTSYLKLIDAWYVALICQNFMVIVSLVVVENLRLRDKAFATKVTPVGVKNLGIGKQPLHLKANFLLKFVFPTILIVNLVAFFSFWTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TBD6</accession>
    <name>A0A423TBD6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001999">
        <property type="protein sequence ID" value="ROT73727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TBD6"/>
    <dbReference type="OrthoDB" id="6365438at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="372" mass="42890" checksum="FA4B6B5A78132B44" modified="2019-05-08" version="1">MIRSVITTPILQTRQQKLTPKDPNLGTKLQKRPHNEVRGIFPKGSLEEMVDSCNDPVLGIQFVYKEVIHGKEKFTCQLCQKSSDVTRIKTSRMFEHLTSLSHNRKYMEIKFGHTKDLLLHFKDEARQIEEREGKIHQPIIDFTHQLPPDLRADLGGYTHSPNQSSSQSRRHRSRSRSHSRRSRSLSRDRDSRSHSRSRCSRSPSRSRRSRSRSTSSTSRSSSISPEESRTSTGHASRVHSKDRKAESPFDKADAVPEQIPLPPPPPPPLPQKPQTAEAEVEVDMHEDPRPILDEIKLLHQSDCKDMLLEDTDMQACMIQTLWTLNLKLDKYYNRSGTTYRLHEDKEVILMSDVTNKLKDYIKQLILIPPESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TC31</accession>
    <name>A0A423TC31_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_007469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001948">
        <property type="protein sequence ID" value="ROT74050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TC31"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="477"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT74050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="508" mass="55303" checksum="0E4AE9240C01FFDD" modified="2019-05-08" version="1">MPSSSPSCCLIFLHATFYQFISTPYFLLFYHISILPSLLSSISFSFSLPFSFSLSMSFLLLPLHVLLLSMSPSPCPLIHVLSPSPLSMSFLLLPLHVLSPSPSPCPFSFSSFLLLPLHVLFSFSLSMSFLLLPSMSFPSPLSFLLLPLHPSPSPCPFSFSLSMHVLSPSPLSIPLLPLHVSPSPCPFSFSFLLSPSPLPCPFSFPSPFLSPFPFFFLSFFFFFSLHIPSPFYSVSFTPSSLFLPLSEILLRLPSLTFEAGLYKRDSSPSTSVLFAPSLLPHLPFLAVRPLLPLSVLYLLHFNFLSSPPPLLSLSLLLPLHTLFRLLLLPSLTFPSTFTPLPSFLLLLFFFIPSLSLSSSPSSSSFPLSLSSSSVLFPFLPAQPHNPPSSPSSSSPPHPSLSLISLLFLPLSSLSSSSPSSPHHPLFLPSLLLSTFPHLSPLPSLSPLPPLPPTLSSPSSTSSLPPFSLSTPPPLSLTFLLPSPPPPSSHPRVTYDLCRPSAQKVPRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TC66</accession>
    <name>A0A423TC66_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_007533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001955">
        <property type="protein sequence ID" value="ROT74001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TC66"/>
    <dbReference type="OrthoDB" id="6381842at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT74001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="395" mass="39936" checksum="C04C9DC68216AB64" modified="2019-05-08" version="1">MTIVNIIRTTPGGQAKRDPVLAEHFLRGKRGLQNSTLSSASHYFHLIPRSEHTSGTMWLKVLTLLGGTCLVVLAAEKAAEAPADASPAEGTEEEDQRDKRNPPHYFLNGWNAMAWREGSGAPFFRQLIHRPGLPPLQYYGRPRNHALLTPDAFDFYYAHPYFYDMDSPSFPVTRAQMQSYCAANFGPGQSTGAPSFGQAGQGSAAGFPPGFAPGSPGSGFPSGAPGSSFPSADKGQTPGGFPSGSGTDSDSKTDSSFFNPTFQQPGTFGGQGGYPGGSPGFNVPSNFGSGRPGSSPFDSTGSGFGFGSPGSPGSPGSSFGSPGSSGSGFGSPGSSGSGFGSPGSSGSGFGSPGSSGSGSARSSGFGSGGSGFGSPGLQASAQFSLGSLLRSAHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TF71</accession>
    <name>A0A423TF71_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase-like protein 21D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_006399</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001811">
        <property type="protein sequence ID" value="ROT75113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TF71"/>
    <dbReference type="STRING" id="6689.A0A423TF71"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF44">
        <property type="entry name" value="PROTEIN N-LYSINE METHYLTRANSFERASE METTL21D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="14535" checksum="170936600F888FED" modified="2019-05-08" version="1">MEKNIMENQDRLGCPVEARELNWGNEEQIREFPIPDVVLVADCIYYEQSLEPLVSTLYKLCSPDTKVLLSYEERTIGNKPLLQKKFFEMMEEHFCKEKIALEEQHELYRCEDIHIYKFSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423THD7</accession>
    <name>A0A423THD7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_005654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001733">
        <property type="protein sequence ID" value="ROT75787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423THD7"/>
    <dbReference type="OrthoDB" id="6355222at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT75787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="524" mass="58433" checksum="04991891FF85355C" modified="2019-05-08" version="1">MRVSGFEPVNAIPANPYGYSEDILKYGDREGAFERFESIPINPYGFSEKIDPHSHSARRLVSGFDNFASIPSNPYGYSEKVDKVDQTPSSFDAVDYIAINPHGFSAKIGRGSASPRRLKNYQLLLLLLKKFRQFQSILMGTQRRLRRIIHLPGFSHQDLSLLHLSPKNPYGYSENVVEISEGPSAFEETEKIPDNPYGYSTKVQGEAHRQHSRPSGFASVAAIPTNPYGYSEKILKYVLPSGAFTDFDSIPKNPYGYSELIEQQHHKQNGVVSGFENFPLIPSNPYGYSSAVEKVKESPTGFEDVESVPTNPYGYSTNIDSSPVSLNSRPSGFENVKSIPLNPYGYSENVAKLDLEKSGFDSVASIPKNPYGYSEFVQREHNQPKTHPSSFERVRKIPRNPYGYSKEIKELGAPEDAFVAVKLVPSNPYGYSTEASKVEISQQQVTEAFEGVDSIPNNPYGFSTQANKYEIESTAFERVDLIPDNPYGFSNSDTVPSESSAFERVDVIGKNPYGYSEKVQTVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TI52</accession>
    <name>A0A423TI52_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lectin B isoform 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_005282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001689">
        <property type="protein sequence ID" value="ROT76140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TI52"/>
    <dbReference type="OrthoDB" id="6344129at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="entry name" value="Mannose-Binding Protein A, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050828">
        <property type="entry name" value="C-type_lectin/matrix_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45710">
        <property type="entry name" value="C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45710:SF26">
        <property type="entry name" value="RH26557P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00059">
        <property type="entry name" value="Lectin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00034">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="6"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT76140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="135" mass="14730" checksum="65572011DC84C3ED" modified="2019-05-08" version="1">MPYQAVGGRCLLLDTLDVGTWHDTRNFCHGYQGELAQIDSADLLTAVVDFIHSQGLTGSDFWIGANNEAEEGVWQWPDGSGVHMGTPFWGYWTSPPRSQPTARAPNTPACSRSISITSMIATSVNFLLCVNIGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TLA0</accession>
    <name>A0A423TLA0_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative segmentation polarity homeobox protein engrailed-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_004141</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001554">
        <property type="protein sequence ID" value="ROT77218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TLA0"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="189"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT77218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="501" mass="53212" checksum="65FB9006A2375D82" modified="2019-05-08" version="1">MTDARARPVSASDRHTPSPLPHSLHLSPRPPSPLLPLSLSPCPLLLLLPLSLSPCYTSPCCSSFFYPFLPAPFPLVPPSPSLSPSSFPPCSTPPSLPFFHLPSLSPSPSLSSLLVLPHPCSSSSVPSFPPARFPLVPPPPSLHFFQLPSPSSPVLPSPSPSFLPFPYPFPSLPFFQLAPPIKYSSSSPLSHPHSSCPPCQVTSSGRDSDRPRSRDHRRQQNKRRHAKAGYLHHFTSPTVALPPCHLAISCHLGHCDRCHPGPLLAIPATRPPYQSLPPRPPCHPLPPAIPATPATLPSCHPATLPSCHPATLPSCHPATLPSCHPATLPSCHLAILPPGRHPLPILPPCHPATRPPCHPATPPCHPCHPRTLPSCHLATLPSATRHLCHPATLPLPPGHLAILPPCHPATCHPATLPPCPTSTLPSCHLASCHPPPFHPAHPAPCHPCLPSCGHLPLAILPPGHLAILPPGHLAILPSCHLAILPPGHLAILHKARDTRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TMI1</accession>
    <name>A0A423TMI1_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cytochrome P450 CYP6BD10v2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">C7M84_003668</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="15">Muscle</tissue>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Microsome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001497">
        <property type="protein sequence ID" value="ROT77671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TMI1"/>
    <dbReference type="STRING" id="6689.A0A423TMI1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11056">
        <property type="entry name" value="CYP6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000042">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050476">
        <property type="entry name" value="Insect_CytP450_Detox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292:SF54">
        <property type="entry name" value="CYP9F3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24292">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 13 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0492">Microsome</keyword>
    <keyword evidence="11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="13">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROT77671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="435" mass="49918" checksum="834B258EA04EE34E" modified="2019-05-08" version="1">MVGDPELLKHVMVKDFDHFTDRSFVTFNEPVMDHMLLGLKGKVWKAVRSVMTPTFSSGKIKQTLQLVKDCAKNLVVYFDKELEKGSSTFEMKDVYGMFTMDTIASIAFGVNSDSLNNTQDEFSAAAARFFSPPPRWKRPIMFFQFLWPQIAKALRLNVIDRTPIHFFTKVVSDTIRYRLENNLRRSDFLQLLLDARLQEQTNNNKGNGSTDINSKKASNEVLNELVITAQCVLFYIAGYDTTATTLSFLSYCLALHPGIQQKCMEEIEEVLRRHKGEITYEALQEMTYLDMVFAETLRLYPPAPRVDRKVTKDFTLPDTDLKLQKGQKITIPIYSIHRDPDHYPDPLKFDPERFSPENKAMRSQMVYLPFGSGPRNCIGMRFALMEAKVAAVYLLQEFAFIPSKKTQVPIVIEQRSGLLKAQDGIWVRLAKRTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRJ6</accession>
    <name>A0A423TRJ6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl peptidase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cathepsin C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cathepsin J</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl peptidase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Dipeptidyl transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_002197</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001294">
        <property type="protein sequence ID" value="ROT79069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRJ6"/>
    <dbReference type="STRING" id="6689.A0A423TRJ6"/>
    <dbReference type="OrthoDB" id="3789175at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.80:FF:000003">
        <property type="entry name" value="Cathepsin C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.80">
        <property type="entry name" value="Cathepsin C, exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014882">
        <property type="entry name" value="CathepsinC_exc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036496">
        <property type="entry name" value="CathepsinC_exc_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08773">
        <property type="entry name" value="CathepsinC_exc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75001">
        <property type="entry name" value="Dipeptidyl peptidase I (cathepsin C), exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019434588" description="Dipeptidyl peptidase 1" evidence="14">
        <location>
            <begin position="35"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="15">
        <location>
            <begin position="234"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROT79069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="477" mass="53351" checksum="0076E1FAF91B328D" modified="2019-05-08" version="1">MRREICGRTVRRRPADEMVSKSVFLLGCLALASADIPVACYYEDIRGTWTFQETERSGDSSLSCDALGPVVHTKTFTLSFPDTATDELGNEGTWTMISSQGFEVNINGRSYFAFSYYEGDWENSVSYCDRTFNGWSRDKTVRNWSCFKGQKNTQVAPRVPKRTQRLQDQQYRVDHRHIAQINAIQTSWTAKAYPQFEQYTIEEMQLRSGGHGSSLPPASPPSSSPELLARLSLLPENFDWRDVEGVNYVGGVRDQAQCGSCYVFASTAMLESRLRVKTRNQRQDVFSTQDVVSCSAVSQGCNGGFKYLIAGRYAMEQGMVAEECNPYTAQDDPCDTDASCARTYVSEYEYVGGYYGACNEELMLQALVEKGPLPVGYMVYDDFRNYEGGIYHHTGFKNDFNPLEATSHAVLLVGYGVDNTTGEKYWTCKNSWGRGWARTASSGSGEEPTSAPSSPWPSTLPLFLKEDLLGNRDVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TRL5</accession>
    <name>A0A423TRL5_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_002181</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001290">
        <property type="protein sequence ID" value="ROT79098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TRL5"/>
    <dbReference type="STRING" id="6689.A0A423TRL5"/>
    <dbReference type="OrthoDB" id="6161578at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070888">
        <property type="term" value="F:E-box binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061564">
        <property type="term" value="P:axon development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016360">
        <property type="term" value="P:sensory organ precursor cell fate determination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11430">
        <property type="entry name" value="bHLH_TS_ATOH1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000025">
        <property type="entry name" value="protein atonal homolog 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050359">
        <property type="entry name" value="bHLH_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19290:SF162">
        <property type="entry name" value="TRANSCRIPTION FACTOR ATOH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="4" id="KW-0524">Neurogenesis</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="154"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT79098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="217" mass="23844" checksum="3249A017CBF5EFEF" modified="2019-05-08" version="1">MEDYFYLEEAAYPSAAYRGTKADFEDVQPGARQDAVGSGGAAAPGDAEGYELTLLESPCVYDVAQYPGYPGGAGDAPYAGSPHFAPHFNQGCDFNAALGKNPAPLPTKDLGLNLLQEPAPHAAPEREKVPPHRTFVRPQRRRRHRPLGKEIVRTRRVAANARERRRMHGLNDAFDRLREVIPCLGSDRKLSKFETLQMAQTYIAALQELLKTSGAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TU93</accession>
    <name>A0A423TU93_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_001233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001162">
        <property type="protein sequence ID" value="ROT80038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TU93"/>
    <dbReference type="STRING" id="6689.A0A423TU93"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT80038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="386" mass="42006" checksum="BADB95DF66AE119E" modified="2019-05-08" version="1">MAFGNRCFWRLLAFEEGVSVERDPSVSEFSPLRQRKEEFGVMKCALLFITQVVTGVSGGGRGWGIGGRPRGQRLAAATHCADVCPGTAGSDCLVGAPRLRFGCCSLSNRTAVSDGGGDGRRWMLRARGGPWRLCFLSSPPHFNLHPPLHPLPYSTHTIASPPTPLLLPHSPSPLDFALRSSLLYPCHSLPYPLDSVPISPRSLPSLYPYCLTPPHPYPLLLLPLYTHSPCFFYSPLPLPTLYSLSPFLPHIILLPPLPNTPLFSSPFNTPFPPFMHPLPLPFYTPLLLILPTACSPPFNPPVSLPHPSYSPLSHPRPSYSPLSHSHPTHHPLPSPSPLQYLSSPYNTLSPPLYPPLLPPTLTPLPHPLYSPSPSLPPPSSVAASAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY49</accession>
    <name>A0A423TY49_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme E2 O</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">C7M84_025536</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="7">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000992">
        <property type="protein sequence ID" value="ROT81302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY49"/>
    <dbReference type="STRING" id="6689.A0A423TY49"/>
    <dbReference type="OrthoDB" id="47801at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057733">
        <property type="entry name" value="UBE2O-like_SH3-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057734">
        <property type="entry name" value="UBE2O-like_SH3-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057735">
        <property type="entry name" value="UBE2O-like_tSH3-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23043">
        <property type="entry name" value="SH3-B_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23044">
        <property type="entry name" value="SH3-C_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23046">
        <property type="entry name" value="tSH3-B_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBE2O-like tandem tSH3-B" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="UBE2O-like SH3-B" evidence="4">
        <location>
            <begin position="265"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="UBE2O-like SH3-C" evidence="5">
        <location>
            <begin position="333"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROT81302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="528" mass="59258" checksum="1CEFE926F0F895E4" modified="2019-05-08" version="1" fragment="single">VTVEQVQVVQLGVRWQCRAFSNDPNVDKEQPKYLVQGEDLKRVKMLNVFEPCTLQLGDRNYYVSKEGDVIMTRDQWRKLMAAQLTADHTNPCPLRPRPAKNKSKRKHRSGLTGEVEQNADAPGAPTSVGGIKDTDGSPVEGALGAEGGLPADDDTKDYNADSDGYIDVDTDEFSDTASISSGASTGSVGRRNKKGPALMTKMMKKRKLKRAKRKTTNEGPAIKTGDQLVVETLMTTSKADVVWQDGSLEKRILSTVLYPIHHLDDQEFFPGDFVVEQDSVDPHEYGVVQRVDHAGRTSIVKWFRTYTAGNEPQPEMLREQEVSVYDLRDHPDFRYRPGSVVIRVANFEECQTCSTGQVLDNFPSGEVSVWWVDGRTSVCYPQDLYKVGEYDSDDGELWDDTASDESWETESEHSVIAEESESESEGVLKTRLVANIEKARIAMSRLEEIFTQNPALQTTAVMKQLLDCYKECRYMDKLMGTSFFHESNFQGLIEKVRERGRASTTQRMTEQINRLFSASDSEGPSLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TY99</accession>
    <name>A0A423TY99_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative nephrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_025407</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000974">
        <property type="protein sequence ID" value="ROT81429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TY99"/>
    <dbReference type="STRING" id="6689.A0A423TY99"/>
    <dbReference type="OrthoDB" id="6347235at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005911">
        <property type="term" value="C:cell-cell junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050839">
        <property type="term" value="F:cell adhesion molecule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00096">
        <property type="entry name" value="Ig"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000405">
        <property type="entry name" value="nephrin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013162">
        <property type="entry name" value="CD80_C2-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051275">
        <property type="entry name" value="Cell_adhesion_signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003006">
        <property type="entry name" value="Ig/MHC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003597">
        <property type="entry name" value="Ig_C1-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013098">
        <property type="entry name" value="Ig_I-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003599">
        <property type="entry name" value="Ig_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003598">
        <property type="entry name" value="Ig_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11640">
        <property type="entry name" value="NEPHRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11640:SF136">
        <property type="entry name" value="NEPHRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08205">
        <property type="entry name" value="C2-set_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07679">
        <property type="entry name" value="I-set"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13895">
        <property type="entry name" value="Ig_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13927">
        <property type="entry name" value="Ig_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00409">
        <property type="entry name" value="IG"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00407">
        <property type="entry name" value="IGc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00408">
        <property type="entry name" value="IGc2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00290">
        <property type="entry name" value="IG_MHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0393">Immunoglobulin domain</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="84"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="195"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="289"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="388"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="486"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="587"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="699"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="Ig-like" evidence="7">
        <location>
            <begin position="792"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="8">
        <location>
            <begin position="897"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT81429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="970" mass="106829" checksum="F19F5BB06AA7DF42" modified="2019-05-08" version="1">MAAIFRRWLAECNLENICRVVKLQPHDPGLPRYEMVGDGINGEHHLKIHNTTLHDDADYQCQVGPADGHDPLRATGHLTVLLAPTSIELLGRGREEVIEVNEGEEITLECQVEDAKPVAMVRWYKNNEEIHLDSRVDVEKESSQRRRHTLVSKVTLRLTPADDGSHYACHAEHPALSQPIAASVKISVLYPPGPPMITGYTAGETIRAGEERTLSCRSRGGNPRPRVVWYRNNEIIDTTDRPIGAESVNEYKFIVDSADNGAVFTCEVRNKLTEKPLLASVKLEVQFPPDKVVVSGPTQSRVGENVTLTCVVENSNPPAEVSWVVDGQPRPEATTRRERAGPGGWHTVSRLELSVPAVDRDMMFTCHATNQALGETKVDTYMLSVLRPPLPPVLHGYSEGSGIRVGSQQRITCVSRGGNPPAHLQWYRDGQKIPSRKHSIDDVSSAEIEIVAEPQDNGAQYRCEAHNSAASSPVSVSTTLVVFFPPETVKISQSPRRLSAGSQAILTCESGPSNPAATITWFRGDYRMAGRLQETSSSLNGGTRVTNVLALNLTAADDGLTYSCQAKNTALQKDVTQSVTLHVNYAPTFLSEPPDVVDVVVGESEELNLTARANPGPVIYTWTRHGLPLPDPVIDDSWRDTYAQHPDMGGAGGSRVSAEGPLLYIRGVTVDDAGDYELEATNQEGATVAKVYLNVQYPPTIKYTSEMVTVSEGQDAHLECAADGNPLTEAMMAWRRDDYDFTKTEQIFGGKKATLTVLRANRNDTGVFTCEVNNSIGKVATANITLVVKTKPVVERSQLLDRAAAEKGKRGELRCLAEGAPDVSFSWKRDGLLLSNGARPDKYENETVRTGLVSWASTFYIRNVHEDDYGRYECIAENELGASTFTVRFIKPTRPDPPLSLKVVNTTHDTVTLAWKPGFDGGKTQYFRLRYRTKDSTSYQYLDVYEAGVSIYTVTDLSLNTEYYFSIMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TYT3</accession>
    <name>A0A423TYT3_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_025205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000944">
        <property type="protein sequence ID" value="ROT81625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TYT3"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042302">
        <property type="term" value="F:structural constituent of cuticle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000618">
        <property type="entry name" value="Insect_cuticle"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00379">
        <property type="entry name" value="Chitin_bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51155">
        <property type="entry name" value="CHIT_BIND_RR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0193">Cuticle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="787"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="866"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="623"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="811"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="874"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="894"/>
            <end position="904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT81625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1098" mass="118239" checksum="62978692D12F1861" modified="2019-05-08" version="1">MGNGTYEFGYDTRGGRTGARFFRHEEKGVDGRVRGQYGFVDANDDLHVILYVTDALGHRIRTETHKIEGYGRELSRMLEQASSSADVKDQINILLEKRKSNPTVTTSSTSSTSTSTSTVASTDPPATTTQTFRTTRGTNLFSDFEPYFSDEDPPATTIRPTLRSLLRSTAFTSSSIRHSTPRPFDRDLSSASVLTRPPTSRDSLRESLDYDDVDRLVSLLDNARSRTTTHPRLRDFSTPATFSGRDDFTSAPSSRPSTLEELRELARSTQSPRRERPDDAGTARPSEASLLPLALGIPVPLRKSLSEDQSDKLRNYLSRILRGDGGESGAIVLGRLNANAFRGSKMSDVLRSLGLIQSDFDDVIRGSNGDPLAVYFDPTAGRETQGQKISNNRANSKPVNEGIIDGGIIDGGIIDGGIVDGGIIGDGGRGFLRGSITSRPLNGDTGGKNLGGEIIDGGIVDGGIIGGSRDDGFIDGGIIDGGIIGGRISTRGKSGRGFNSGDIIDGGIIDGGIIDDRRVDNFNNGRRGKTIDQPSARDFASQPRGSTSQQYGNAKSLLTPPPTRPSSRRPSSRRPSSAGGSSKTSLLDQASLIDQLIAFHKPEYPEGFKEREAFNNPSEASRQRGLSQGSGQNGNQINSRTQTTQPAQGKQIAETQSQVEGPVRMPEVLHYIPSPDLSTGRPSDYQVPAAPRPSENLGKSSESVEVTPPNTEQKSNDNRNPSAVNLVSPADDNFGVRPVSVSSLSPNRSPVFINSTVYFTTTAIPDILHSNLIRPRLRQSGQSLFAKELRQESDSSSDESGEQKTDRDLGRTNNRISQPVNSLDIETSNARERPREGQGIGTASLGSSGHIPSKIDTIVLPAFFDTTPQPLPSTPKTTRPTTTAPTLKRPPPTTQQTTRQLVPTAPSGPPSASLRGTNRGRLSHFPVNSREQGAFRRIVPTNAPPTQFPTTTLRGTTLSRFQSLRKPPRVTTLPPIHLPTTAVHPTTTAITQVFSRPIIGTPDSFFPTASAEVSSNGRALNSKPPPIVVNNPPIHLTTVLPPSVALLRSPQGLPRVRPEDVVPILHHGPPLIPTLRGPTFPHSRVRSYRLGSGSIHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZT5</accession>
    <name>A0A423TZT5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Putative basement membrane-specific heparan sulfate proteoglycan core protein-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">C7M84_024879</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="18 19" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="18">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Extracellular space</location>
            <location evidence="2">Extracellular matrix</location>
            <location evidence="2">Basement membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000901">
        <property type="protein sequence ID" value="ROT81969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZT5"/>
    <dbReference type="STRING" id="6689.A0A423TZT5"/>
    <dbReference type="OrthoDB" id="10055367at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005604">
        <property type="term" value="C:basement membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000033">
        <property type="entry name" value="Laminin subunit alpha 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000034">
        <property type="entry name" value="Laminin_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050685">
        <property type="entry name" value="LDLR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023415">
        <property type="entry name" value="LDLR_class-A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002049">
        <property type="entry name" value="LE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270:SF61">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24270">
        <property type="entry name" value="LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00052">
        <property type="entry name" value="Laminin_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00261">
        <property type="entry name" value="LDLRECEPTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01248">
        <property type="entry name" value="EGF_LAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51115">
        <property type="entry name" value="LAMININ_IVA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01209">
        <property type="entry name" value="LDLRA_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0084">Basement membrane</keyword>
    <keyword evidence="12 15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0272">Extracellular matrix</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="14" id="KW-0424">Laminin EGF-like domain</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Laminin IV type A" evidence="17">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="669"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="16">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="522"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="15">
        <location>
            <begin position="580"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ROT81969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="690" mass="77511" checksum="9657CD88A597CE62" modified="2019-05-08" version="1">MHVHDGDFKPDFENQVDVRFEIGQWFKRVVGRGQIVQSQEPANREEIMMVLENIELLLIRALYTDAYYVVSTLSEVQMDTAVIHDNTQGRAVLVEECRCPTGYVGLSCQDCAPNYKRVSDGPWLGRCVPDVECRPGEYGDPANGIPCLPCPCPLTTPTNQFSSTCFLDSDGQVTCNCLQGYQGRRCEVCASGYEGNPNVPGDSCRPETVCMTTFTCPDGTVHPWSRRCDGIKDCFNYEDERECDVCFNSGHKCSDRHCIHFERICDGHQDCYDGSDEFPENCLDYLPCDHISKWTCDDRTCIDRRDHCNGVFDCPDGSDELYCNCSCTSPNQFKCQDGTCLSARVRCNGQADCKDGSDEWGCCNEATEHACGDGTCIDRRRVCDGQYDCSDYSDEPSYCARNCDPNTMHQCGDGTCIDRRRVCDGQYDCSDYSDEPSYCREICDPNKMHQCGDGTCIDRRRVCDGQYDCTDYSDEPSTCQTYCDDQYEFTCRNGDCIDRRRYCDGYSDCRDGSDEYNCPQKCSEYEFQCGDGTCIDQRQLCDGRADCRDSSDESQQAGCCVGPYYFQCRNGDCIDASLVCDYRENCYDGSDEYGCSVDCNPSGSYSVQADPVTGLCQCKRPHSEPRFLPLPVQPSSVPTPCATFQRPHSEPRFSPLPEQFSIIPTPCATMEPRRQGRSFGPFPPPPPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2024-01-24" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423TZW7</accession>
    <name>A0A423TZW7_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mutator-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_024854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000898">
        <property type="protein sequence ID" value="ROT82000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423TZW7"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049012">
        <property type="entry name" value="Mutator_transp_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20700">
        <property type="entry name" value="Mutator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mutator-like transposase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT82000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="47094" checksum="B226BDA5F1072089" modified="2019-05-08" version="1">MCGEVSHTSPETFPLTDTTRGVFTAMLVYCSLVNDDGYASYCRAERFFNSKIQLAHERVKEFYRTDQNVAPDADGISDIIVSFDCAWETRGHQSHIGLAFIVEANTGAILDKQVLCNLCSVCERKRQSLPANDYANWFLSHTHCSKNFDGPAGRMEAEEAQRMFLRSTDFGLWYAYFVGDGDSSAYRSVRFIYGPDREVVKYVSVNHVGKRMGTRLRKLKGTLTTPVTTRTGRVMRRSLLACTLINKNIDLSSRLSTLALKRSIKPAWRTCGRTQRAFLLSFFQRFLGAAPVLSRCADSWCFYNTARAAGRVPRSHSQENLFLRTVPPAVLQEIRAVYEDLTKDDLLSRCLPEYTQNPNESLQSKVWRKCSKSKFAGKLSAVLPMEDTPTLISNCRSRGGSESELQPELSDASAAAVTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U0X5</accession>
    <name>A0A423U0X5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000840">
        <property type="protein sequence ID" value="ROT82339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U0X5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="434" mass="47902" checksum="3ECCC2DA9017757E" modified="2019-05-08" version="1">MPSRSPSAESYQAFLPSAACSPLRTLKQVLSAISPRVDSQSDTAPTCPDVHGKVPAKAPDGRRRRRAWALAEQSDADSVCQSHLPEEALGILQNRSISRRAFRRHLHPSLFSPSCLSPSPSFFTSSTSPVTLGPSSSFFFTPPSPLSSLLVLLLFHNRYFSLFYFFSSSSFTAVHLSILHLSRPLLLLHHIYRFLPCLLHRPLLSLLLFLHHLLPILLLFLHILSPPTFSLSTLSVFLLFLHHLLAILLLFLLSLPIFPPSPINYSPPLPPSPINYSPPLPPSPINYSPPLPPSPITILLLSNIPPHILSSTSLCPPPPIYSILLLFSLYSPIPFKLFSSSSSITYSLFSSSPSTFFHHHHSFYPLPLSSSSSPAPLPQHVARPAPLATHDTCALGTRLGEAVTSHAEECHKICTLSFFTFSLSLYLIENMIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U243</accession>
    <name>A0A423U243_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_024062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000776">
        <property type="protein sequence ID" value="ROT82776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U243"/>
    <dbReference type="OrthoDB" id="6371339at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="139"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT82776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="420" mass="47135" checksum="7DE66BF3D5F99566" modified="2019-05-08" version="1">MFFRERGTPLISRGNLVERHQRDDPLWQQLIEYLEEGRLPPRRIPLPLDQFELRDRVLYHVKSNNERALLQLVIPRSLRGAALDAVHAVPSAGHQGVHRTYQRLRDHFYFPGMLAASRRYVASCTACQRRKGAIARTPLQSMPDVAEPFERVSVDILTLTPSARGNKYVLVLIDHLTRFVELFPLATKDAQTVADVFLAEFVTRYGPPRTLLSDNGLEFRNRLLSDICHHLQLGWPLVRPPERLVSVGPPITIEGGGLDRGSITKGIWSLCIAALSCTPVTEPDPWVPDEPQRDACCPLLITSPSCNITLYDLGPNTLAACSFSEPSLHPARGVGNTLDDHLQMDGSRAQQPASVLRNDPVLSYSQPPLIYAGFLAFCLRFWQGRAFVLDVCRNPVQLLFLLSLAKLWLVFTPRSTVTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2D5</accession>
    <name>A0A423U2D5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_024046</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000775">
        <property type="protein sequence ID" value="ROT82802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2D5"/>
    <dbReference type="STRING" id="6689.A0A423U2D5"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF38">
        <property type="entry name" value="SODIUM-DEPENDENT DOPAMINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0769">Symport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5019419825" evidence="10">
        <location>
            <begin position="21"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600175-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT82802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="159" mass="17349" checksum="000591823658C8B0" modified="2019-05-08" version="1">MPYVIMTVLLIRGALLPGAADGLLYYIKPSISALSKPQVWYEAAQQVFFSVGAGFGVHLSYASYNNFNNNCYRDCLITSLVNAFTSFYSGLVIFTYLGYMAFKQKTDIGTVATDGPGLVFQVYPEAVATLPGSQFWSCLFFLMLISLGAKNTLTAPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U2K2</accession>
    <name>A0A423U2K2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_023914</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="1"/>
    <dbReference type="EMBL" id="QCYY01000759">
        <property type="protein sequence ID" value="ROT82929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U2K2"/>
    <dbReference type="STRING" id="6689.A0A423U2K2"/>
    <dbReference type="OrthoDB" id="422540at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042575">
        <property type="term" value="C:DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="8">
        <location>
            <begin position="322"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="496"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT82929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="578" mass="66438" checksum="D4E66E865A059FCE" modified="2019-05-08" version="1">MEKQLRKFLGMFNFYRRFIPGCAQLLKPLHALITPNRASRNTRIEWTSSTNETFQACKEALAAATLLNHPLPEAPLSIAIDASDTAIGAVLQQRQGKQWQPLAFFSQTLLPRQSRYSAFGRELLAAYSAVRHFQPSVEAKEFHILTDHKPHTFALHSRTRRQSPREERHLDFITQFTTDIRHIRGSDNEATDALSRVSISAATLADDAVDYHLVSREQRQDTSLTPLLKGQTSLYLERVKIPNSCDDLLCHVSLGYPRPYIPPSLRRRFFDAYHQHRGIRATQHLIRSKVVWPAINKDVRQWCRSCIECQRNKIHRHTKSPLQTFPIPDSRLQHVHIDIVGPLPMDDGYSYILTMIDRFTRGPEATPIRDITAAIVAKTFLNTWISRFGTPETVTTDRGAQFESELWRHLLILLGSKRIRTTAYHPCTNGMVERLHRHMKQALTSSSPNRRWVDQLPHVLLNIRTSFKEDLRRNGLRDNAHPPCRVTCHSQQLRTRDLRQTTLRTNGLGTQPTDETHPTAVHIHASRTSGLLSRLREKTSQTSSLSSVRGSIPGHPKRRQDDHHPPPKGRRHRDHRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3C6</accession>
    <name>A0A423U3C6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023613</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000718">
        <property type="protein sequence ID" value="ROT83208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3C6"/>
    <dbReference type="OrthoDB" id="10022757at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="313" mass="33527" checksum="AA74DEC49F33D1DA" modified="2019-05-08" version="1">MFSSFQTASLSSSPTGFPPISRPNIVSMWGIGGFTSPALPTPPAVTPNTIASTLGNPQMPSVTFFNSRAPMGFNFRMAGSHLGTPYVYKRKPEDELEEVKPVVKQHITEEKMSAHLNALHLSESYCNHKLGKKGLPSEVELSEDSDEGLGHFGEDQDGMLMDAKGPMRLIISDERGETSASSSPDSGISVSSPPPSLSFLGQQSSRVSPFSAGSVSAEAGDDLLSLPSTSSGSRGGGYLPPLRRPASPLPDPMADDDFSERMEFNNNNGNAPNFMWLEENNNSALIDLNAVEPQRAPLLDDLPDLPDSDDMDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3D6</accession>
    <name>A0A423U3D6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_023604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000716">
        <property type="protein sequence ID" value="ROT83221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3D6"/>
    <dbReference type="OrthoDB" id="10012075at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036179">
        <property type="entry name" value="Ig-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48726">
        <property type="entry name" value="Immunoglobulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT83221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="14006" checksum="E33D26DF9A8FF3F7" modified="2019-05-08" version="1">MANTVKGDAASGYIRSRLYVREASPADSGVYSCWYGNYTSDTVTVHVIAGENSAAMQHDALPDATPSRGSSLSRPAGLAIYLHLCLLMALYSLASGSSVGARLLGQNGDAPRIPTGDPTSLPACETLLCSGGLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U3P9</accession>
    <name>A0A423U3P9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative Ras GTPase-activating protein isoform X1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">C7M84_023502</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="6">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000700">
        <property type="protein sequence ID" value="ROT83334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U3P9"/>
    <dbReference type="STRING" id="6689.A0A423U3P9"/>
    <dbReference type="OrthoDB" id="5572587at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04013">
        <property type="entry name" value="C2_SynGAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05136">
        <property type="entry name" value="RasGAP_DAB2IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021887">
        <property type="entry name" value="DAB2P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF60">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN RASKOL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12004">
        <property type="entry name" value="DAB2P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="4">
        <location>
            <begin position="82"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="5">
        <location>
            <begin position="254"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="823"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="886"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="983"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1128"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="823"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="906"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="933"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="948"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="983"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1132"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1146"/>
            <end position="1163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROT83334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1163" mass="130046" checksum="4AD59EB6FCB5398F" modified="2019-05-08" version="1">MRVGQPSRTWVLRQWSEIEGRDAHSGQRPPPDNAGLLYEATVLARVTSTLESADDTLRSARSHESLQSASYPHDHESTPSPLHERSRIPANRDEVRRTENTLKIWVMEAKGIPNKKKYFCNLILNNELYRRTFSKMKSNMCFWGEYFELNALPQVSTICIELMREADKKPGYKKIGTVEIDLKPSSPGRAALVEQWYPVKVDKPDREIPTLRIKHRFQSLDILPLPQYGAFRQYLKDNATSLCQLLEPVVSVKSKEDIATTLINIMQKEERAITFLVSLILTDIQRIGEKKTENEHLLFRGNSVATKAIEAYMRLVGEHYLQETLSDSIQAVIATSEDLEVDPLRITNIQYLPRQREVLKERVCSIWEKIIQSGRSFPVELRKVFHTIRERLSRQDKCELTDNLISACVFLRFLCPAVLSPSLFNITQEYPDERAGRNLTLVAKTLQTLANFTHFQGKESFMEFLNDFIDKEQEKCRTFLRTISSPPNRDETELEFDGEIDLGKHLAQLHLHLTEAIAKIDTQGYESEASKVLALVEDINILLGSDQKDLSSAASRQMFTPPLVPSSSSLPSATHPNNNYIRDGCGEGLNVVDAQMGIVMAGGEVDVGLSVPTTNTPRSQSLPRAATPIYTHHQMQASISPSINSPYRDKTAANDLSTSDDYVLITAFDHQAEPQNFMYPSIEANNNNSPLTDMRLSNSNTYYMAEVAPPSSPMRQTSSPGPHVAGGMHQPLRGHVHHRLHPRATAMSSRSHSLTGVSNAIERRAVYQDECSELYRYMDSCSHKIHALCMDSENNIQGSQTSISQLSNVASSGYQSFAYSQSSSPVDSLLHTDNSSLLSRENGNSGPPGGLRQVLHGSPVASPMHQPHSAKHRAVAVHPAYLGHAGHVSLHGTPRHIPRVPQPKGSPNSSLSSSQSVEDLSSLRRGRTRQRRSASSSSDSSPDTRPASHSHSHSRRPHAHPPRTNPHCSPRLAASQALRHELRARSRYDRSASGRRGKNFRSCEREDYPRGSSHCFDDSEDEMSIVTRASTGGGVGMGSWAKDGRRLSQDEHIVPSTIASQQILDQQEDQMRAIVERLMTMEQEFRHEQELMRREMHDKDARIDAQAKKIAALDSANTELIRTIASLSTRPSDMKATDHELPGDTTIDSCNASDTSDYKSSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U561</accession>
    <name>A0A423U561_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_023043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000632">
        <property type="protein sequence ID" value="ROT83860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U561"/>
    <dbReference type="STRING" id="6689.A0A423U561"/>
    <dbReference type="OrthoDB" id="6363663at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049352">
        <property type="entry name" value="Rost"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF49">
        <property type="entry name" value="HEADBUTT, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21534">
        <property type="entry name" value="Rost"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT83860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="122" mass="13866" checksum="E32170683D5B6024" modified="2019-05-08" version="1">MPGMYTLLDIAVSATPRRLLHAYQPSAFLTIYTLFNLIYYLCGGVDYQGRPALYPVLDWTRPGTTISIMATVLLGLIPFLHAIICGLYAARVKAWRILRISRYVREEDETDQVEQAAQEQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U638</accession>
    <name>A0A423U638_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative glycine receptor subunit alpha-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">C7M84_022627</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="9">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000585">
        <property type="protein sequence ID" value="ROT84177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U638"/>
    <dbReference type="OrthoDB" id="6351594at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005230">
        <property type="term" value="F:extracellular ligand-gated monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00112">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.400.10">
        <property type="entry name" value="Low-density Lipoprotein Receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.170.10">
        <property type="entry name" value="Neurotransmitter-gated ion-channel ligand-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.390">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036055">
        <property type="entry name" value="LDL_receptor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002172">
        <property type="entry name" value="LDrepeatLR_classA_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006202">
        <property type="entry name" value="Neur_chan_lig-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036734">
        <property type="entry name" value="Neur_chan_lig-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006201">
        <property type="entry name" value="Neur_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036719">
        <property type="entry name" value="Neuro-gated_channel_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038050">
        <property type="entry name" value="Neuro_actylchol_rec"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18945">
        <property type="entry name" value="NEUROTRANSMITTER GATED ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00057">
        <property type="entry name" value="Ldl_recept_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02931">
        <property type="entry name" value="Neur_chan_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00192">
        <property type="entry name" value="LDLa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57424">
        <property type="entry name" value="LDL receptor-like module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90112">
        <property type="entry name" value="Neurotransmitter-gated ion-channel transmembrane pore"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63712">
        <property type="entry name" value="Nicotinic receptor ligand binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50068">
        <property type="entry name" value="LDLRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="585"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="720"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="Neurotransmitter-gated ion-channel ligand-binding" evidence="8">
        <location>
            <begin position="364"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROT84177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="756" mass="85667" checksum="1ECD7A262478141F" modified="2019-05-08" version="1">MVNHSAPFPFGTPPLEAHMWYHLCLTVNDSVVKLDIGNEEYEVSHQNVAKLPRMGEGDVEHAYVMLGNNHTSFEFFGQIADISLYQDPLSQEEIQSFIECGSDISLGLEYSLDNDVQEHSQKQARSGLCRPRPDYFAVLFSGLRDQRTSKEFCEHLGARLASTKDDYSYILSDIFFSMNAQSMATVWTEDQVDQVADHHVMLFLMKMGNESSYMNMSISSTTDAANTLCMVPFGKKIYMLRDKREEYTFFSRKGRLVLQGLGSSLIFISKCPGDMEGSCIFYSKKNSRKMYHVYDDNSFLLGRREWRSLTSKGTQERAISVTLTACDESQFTCNNSQCVDLENRCTGMAECEDLSDEGDTCRAMDHLPLTYWSNMCPHVSGRPPLIGLFVQLVSINEISLENNEFKATLTVSTQWKDARLTFSNLGNCTNKLLPEIYESIWVPAIAFENANYDDNRHIQQGTEILQSYTVEADGTNYTDVLESFEATKNNGTEALLRRTIKYLFKFSCDYEYQLFPFDIQECEIVINLPSQTYSCPLAWDPARIAVFGNSSTISTYHVDPVRYVFDPEKGGTVKLKLLFTRKFDAYLLTTFLPCVLLCVLSELTLFYFDLDAFTDRIAITLSLLIVLASLFAQVATSMPASPSPKLVDIFFFYCILRVSLVFLLHSAIDRKKRDLERKEKEGSSDDVVVLKDLDIKMNIAWSQPSKSEEKAKTTSFINNMGLVVLMVLDAAAVVGFVVWILVARATTLALYDTYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-05-08" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A423U7C5</accession>
    <name>A0A423U7C5_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_022185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01000520">
        <property type="protein sequence ID" value="ROT84594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A423U7C5"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT84594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="524" mass="58316" checksum="59278D801BCC7FBE" modified="2019-05-08" version="1" fragment="single">DGGGDQGPPQDLLSRPEETRTSSATRRPRTCDRRRPKPQRTGGDKASADQTKDAPQRRKRPTDPQRTGRRPRTSQRTEGDQGPPQRTGGDQGLLSGPEETRTSSATRGDADDLLSGPKETKDLKAQRTKETTDLLSGRRRPGPPPDHGLLSGPERRPRTSSADRRRHKDLLSGRRRIHRTSSADRGRPWTSSGRPEETKDLLSGPKETTDLSSGPKETRTSSGGREGARTSSAGRRRKRTSSDRTRKGDKNSSADRRRQGEEGGKASSADRRRTRTSLVDRRRPRTPQRPEETKTPQRTGETKDLLGGSEETTTSSADRRRPGGLLSGPDLLSDREETKDLLSGPEETKDLLSDRRRPRTLSGRGETKDLLSDRRRPRTSSGRSRRRPRTSSADRRRPRTSSADRKRHGQPKEPLLRDRRDQGPPQRRGGDKDLLSQPEETKRPSSATEETKDLLGGPKETTDLLSGPEETKDLLSRPEETRTSSQDGGDQRPPQRTGGDPRTSSADRRRPRTSSADRRTPRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LRU7</accession>
    <name>A0A3R7LRU7_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Prophenoloxidase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">C7M84_021009</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="8">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004270">
        <property type="protein sequence ID" value="ROT61249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LRU7"/>
    <dbReference type="STRING" id="6689.A0A3R7LRU7"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1520">
        <property type="entry name" value="Hemocyanin, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.10">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013788">
        <property type="entry name" value="Hemocyanin/hexamerin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000896">
        <property type="entry name" value="Hemocyanin/hexamerin_mid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005203">
        <property type="entry name" value="Hemocyanin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037020">
        <property type="entry name" value="Hemocyanin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005204">
        <property type="entry name" value="Hemocyanin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036697">
        <property type="entry name" value="Hemocyanin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511">
        <property type="entry name" value="LARVAL STORAGE PROTEIN/PHENOLOXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11511:SF4">
        <property type="entry name" value="PHENOLOXIDASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03723">
        <property type="entry name" value="Hemocyanin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00372">
        <property type="entry name" value="Hemocyanin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03722">
        <property type="entry name" value="Hemocyanin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00187">
        <property type="entry name" value="HAEMOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48050">
        <property type="entry name" value="Hemocyanin, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00210">
        <property type="entry name" value="HEMOCYANIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="7">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROT61249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="727" mass="82943" checksum="43EE714ED0660A92" modified="2019-04-10" version="1">MSQRDLRQPHSFPRLRRGRSSLLSSSRSDTSFRLSSMNQRTMANDQQRLLYLFELPQEPIQTPRGGGSVQFKLENDDTPPSVATRVGLSPSVSVPVPERKDVALQDLGTATSIPMGSAFSFFLASHRRAARDLCNVFMKTNGAEDLMQVAARVHGKVNETLFIYAISFVILRKKELHSVRLPTMVEVFPSRFVPQEALSRAQLQVNRMDPNQSEAVIIEHGPEFSGSPVKPEHRVSYWREDYGINVHHWHWHLIYPPGMGVDRDRKGELFYYMHQQIIARYDMERLSLGLPRVQKLDNWRVPIEDGYFPKLTVNNSGRAWGSRQDNTLPKDFRRTEIGDPVDITDLEIWRARLLGAIHQGYMVDRNGDKVPLRDDVTSGKRGIDILADALEADADHSVNFPYYGDLHNIGHDILAFSHDPDNAHKEEMGVVGDLGTSLRDPVFFRLHKLVDDLFQEYKLTQPPYKEEELFLPGVRIERAGVVRDDEADVLLTGWNTREFEASRGIDFNGRPVILRLTHLDHKPFDYHIQINNDLREPKEVTVRIYLAPKFNGREQEMNFMEQRILWCELDKFTVHLKPGKNHVVRSSKESSITNLEELTFKDLENSGPGNSSEQSAFNFCGCGWPQHMLLPRGRPEGMAFQLFFMLTDYAKDKVSNPGGVRRCANGVSFCGMQDAKYPDARPMGFPFDRRPAPTLQGLPVNTTADYARLGNAFMHDVTIKFLGDKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSG9</accession>
    <name>A0A3R7LSG9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018904</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003472">
        <property type="protein sequence ID" value="ROT63222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSG9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="382" mass="41545" checksum="696E46DD3C2A1722" modified="2019-04-10" version="1">MRSDQTVLHPEEATAREASDVCLLDSPPPTLTPTLPHSLFSLPILFLVPSFSYSSFSILFLFLSFSYFPSPYSFLSFFLLSPSPILFFSLLSPILLLLYFLSLLSSLLALIPSPYSLPFLSFLFSFFLSLSLLSSSSLSFFSFPLFPPLLFSLYSLIPLSFSFHNPVHLFPSPYSLSFSLIPILSFHPSPSRSPFPPFPSHPRFLIPFSYSFSLSSPSPPSPLSLSSSSPSPSSLPSPLLNPIPSPFLSLLLPPPSYHQPLPSPPPPLPPLQTLPTFSYPLPLPSPPLPSPSPTLPGLLYTLLPPLPFPLSNSPSLPLTPSPPSPPPSLFLPPSPSLLTPPSSPSPFPPSCAELHLPCQKQRGMLPTAGMNVKITLKLLMNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LSS9</accession>
    <name>A0A3R7LSS9_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_018621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003434">
        <property type="protein sequence ID" value="ROT63483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LSS9"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="700"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT63483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="727" mass="79332" checksum="44AE270A0726FCC1" modified="2019-04-10" version="1">MSPTPPPVPVPPPVGTYSRRRSWCHPAADNAQTIAFQGGTAFHAAVCCLPLFKPPAAKGPQLAGGGGSQRAPGPRPIKHRRQLEQAEADSSVMQHIERDAISDALRPPPPFRPLNNISLCSARERTHAAGTKSTRARCYVPAARTPAVRRYATHAHDDEPDDGRKKCMRASAWQTNAVSESPIASVHEGIACRGREEGRPWWGGTQDKTAKDEKEQKARRHNGMKINPRSASDPRASPRPRPPRQPFRNPVRPRPCADRGHLRSRRTHPFPSNCEKKPDEKRTSPLGAASCSSRARMHAFGDGRYARPVNGFRPKPFRRTRHRRLRIPSPSAAGNPWRRLPAQSFRCRSLSLICRPGFGADRSERRRRQSVKKRAPRPRPPEASAISPPRARPPASSRAVRSAESCTLPSGAPALAASRRQESAAVLRTDPVRASLGSPRTKGPAAVSRQRRQRSGVAVITVLRAARRSGQRGGSRPRCLSAQEYVTAESASLRRTTASTWPVAGAEGRAPEFLPRGGLALGRGGHRGHRGGPGTQDLGDVALLPRGLGARLGPAAAPVRLGPLDAPPPLRLSCLRWVSPPLFPCSCCSFSSFSLTLHSPRDSPVPRARPGTKGIPRDCLRVFRQIEVFLLLFTSLFFLLYPPFFSSSSSLSTSILLRFSPFLLRFLFFFPLSTSPFSVFSPLPPLSPALPSPFSPSSSLHFLLILSVYLPPPIPFSCFIPATKNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LTD2</accession>
    <name>A0A3R7LTD2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Penicillin-binding protein 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003705">
        <property type="protein sequence ID" value="ROT62372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LTD2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="432" mass="47862" checksum="89A635DBA7E77B6A" modified="2019-04-10" version="1">MTSLPRFRRSIASPIQLEEVEDDAHSGVRFPSRTGSLPRFRRSRTTPPSLPRFRRFASPIQEVEDDATSLPRFRRSRTTPRFPDSGGRGRRHPRFPDSGGRGRSHPRFPDSGGRGRRPRPPESGKRGWRPSRPPGRQEVENPTLASPIQEVEDDATLASPIQEVEDDATLASQIQRSMTTPPSLPRFRRSRTTPPSLHSGGRGRRHPRFPDSGGRGRRHPRFPDSGGRGRRHPRFPDSGGRGRRHPRFPDSGGRGRSHPRFPDSGGRGRRPRPPESGKRGWRPSRPPGRREVENYPTLASPIHEVEDDATLASPIQEVEDDATLVSPIQEVDDDATFASPIQEVEDDATLASPIQEVEDDATLASPIQEVEEDATLASPIQEVEDDTTLASPIQEVEDEATLASPFQEVEDDALDLLNRGSEGGVLLVLRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LX21</accession>
    <name>A0A3R7LX21_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transportin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_020634</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01004102">
        <property type="protein sequence ID" value="ROT61561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="599"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="937"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1076"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="853"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="812"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="867"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT61561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="1403" mass="148353" checksum="79DD33941620D439" modified="2019-04-10" version="1" fragment="single">DGPRTVLILCLRRLSFFAPRFHSRALGPRPLVSSRPLGVFSGPWVSLSGPSVSPRASVPLGPLGVPLGPLGVPLGPLGVPLGPLGVLPRALVSSRAPGVLLGPSCPSLTLVPLGPLGVLLGPPRCPLSGPSCPSRPLGCPSRAPRSLSSPLGVLLGPSVLGPLPSSGPWVSFSGPWVSLLGAPGCPSRAPRCPSQALGVLPWALGVLLGPLYVLFGPLGVLGLFGVLLGPLDVLLRPLGVLFGPLGFLLGPPVSFSDLPGVHFSDPRCPSRTPGVLLRLLGVLLGPLGVLLGPLGVDPSCSFTDPSGVHLSSDPLGGPSVSSRTPLSLLGPLGVLLGPLGFLLGPPGFFLGPPGVLLGLLSVPFSTTHCPRCTFSNTSLSFLEPLAFSSRPRAVLSRALRCPSRTPFGVLRTRTTLVSFSDPLVSFSDPWFPPRTPRCPSRTPRCPRTPSLSFLDPSGVLSHHLAPHWCPSRTPRCPSRTPRCPSRTPRCPSRTPRCPSRAPRCPSRTPRVPLGPSVSSRAPRPSRPSLPSVSLLRAPGVLLGPSCPSRAPRVLLRAPRCPSRAPRCPSRAPRCPSRAPRCPSWAPRCPSRSPRCPRPLGVLLGPLVVLLGPLSVILGPLGILLGPLGPFSGPRCPSRAPRCPFSAPRWSFSGPSVSFSGPRCPSRAPRCPSRAPRCPSRAPRCPSRAPRCPRAPRCPFRAPRCHSRAPRCPSRTTHCPRCTSRTPLCPSWAPRLPSRAPRCPSRTLWCPSRTLWCPLDSLFGVFSTLWCPDLSFSDPRCPSRTPRCPSRTPLFPSRTPRCPSRTPRCPSRTPRCPSRTPRCPSRAPRCPSSGPPCPSRAPRVSLFGPIGVPSRPLGRPSRPPRCPLGPLVSPSGPRGVSLSGPSVSLSSPSALVLLVRSGCPSRPRCPSRAPRCLSRGPSCPSRPLGVLLRPFRVLLGPLGVLLGPLGVLLGPLGVHLRALGVPRRLVLLRPLGVLLRPLGVLSRPLFLGLFVSFSGPSVSSALVSFSDPSMPPGPSCPSSGPSVSSRAPRVAPLGAPRCPSSGAPRCLLGPRCLLGPRCPSRPSLSSVVLLEQLFVLSWCPFAFLLGLSFSTLWCLSLRLFGFFSGRLFGFPSQTLWCPYSGLLWVNPSLRLLNPWCPSRTSAVLLGPSLSFSDPSVSFSDPHCVLTSDPFVNIFSRPLGVPFSGPSVFLLRALGESILGPTQLSSVYFSNPSLSFWAPRLPSSGPFAVPSRLFGVSFSDSLGVLLGPSCPSRTPRCPSRTPLFPSPTNSVSFSDPGCPLRNPTLSFSGPSCHFLGSRCHSRAPRCLLGPLVSPARASRVPLRCPNYGNPPTRGPTVSLSEPHRWLPLGPLSVVPLLCPLGAVLLGPWCPYRPLGCPSQRSSLRWYHLHIDASLGGRVLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LXL8</accession>
    <name>A0A3R7LXL8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_014699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002830">
        <property type="protein sequence ID" value="ROT67233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LXL8"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT67233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="379" mass="39483" checksum="26FA1E10E37AB138" modified="2019-04-10" version="1">MNFLYLPISSTSFGLLHCFLHFLFPPPLHCPPSLFIPSTPSIALPPFLFPPSSSPPPPPIPSHQAHLLHTSTTTTTVSTPFPPSPSSPPTPSLPSPLSHPLHPSTSSTPSPFPTPPSLPPPPPPPSPPLLPSPSPSTPSTPTPFPTPSTPSPFPTNPPPPPLPSTPPLPSPSTLPLPPPFPPLPPPPPPLPSLPPFPPPPPLPLPPSFPFPTSTPSPSLHLLLPSPSHLHSLPSLSFHPSLHSLLPSLLSTPSTPSPFPLLPPHLLHPFHPSTPSTPVPPSFPPPPLLLSPSHLHPSTPPLQSLPPSLPLSSLHPFLPFPPLPLLPSLPPSTPSTPPPPSTPPLQSLPLSPLPPLPPHPSTPLRHPPAVFGISCEAVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7LYC6</accession>
    <name>A0A3R7LYC6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_019775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003703">
        <property type="protein sequence ID" value="ROT62383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7LYC6"/>
    <dbReference type="STRING" id="6689.A0A3R7LYC6"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000043">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF53">
        <property type="entry name" value="GH23275P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT62383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="172" mass="18855" checksum="30203BDB18AECEA5" modified="2019-04-10" version="1">MDDIWGFPGIAVIHGEQKTNEDEQADGRNSPPLVEHSRIMDVGVGVPALAAKEKPPINVVGDVGGRIAIMVDDMIDDVASFVAAAEVLKDRGAYKIYVMATHGLLSSDAPRLIDDSPIDEVVVTNTVPHEIQKMQCHKIKTVDISILLAESIRRIHNNESMSYLFRNVTLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M1X8</accession>
    <name>A0A3R7M1X8_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Zonadhesin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">C7M84_012248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="1 2" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="1">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002554">
        <property type="protein sequence ID" value="ROT69554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M1X8"/>
    <dbReference type="STRING" id="6689.A0A3R7M1X8"/>
    <dbReference type="OrthoDB" id="6360232at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ROT69554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="731" mass="82539" checksum="613CFFECCF33A5AC" modified="2019-04-10" version="1">MTAIRACRSPVSSDFQEYSSPSLRLLRFLSDVALDGDVAAAGSGSAEPQGYNYEEPDNQYLPPAKCKLAPVTSVVYNTQLQTSVRLQTVCHQTVPSPPVVQTRFVTSTRVVPQVNYVTRTQVQTQVVPVEVTSTQVRTIIQPLTNYQTQERQATRVVTVPGRDVVQTRVQTVVQTSIVRSQQPAITRFVTSTRVQQLLKTSVVRGQDVVRTTVAQRQQVIPFTSVNTRYENVVATRQQVVTRTNIATQTRILTQVVPQEVVRTQVVPTTIYTTLFETRVQPFTRVQTVVRTQYVTPVPVVQTRQEVRTSVVQVPGQDRVVNREVVQTQQRQQVVMRTLLLSLLVGCAFGASVERPRRQVFGARINLESSYLPPKEEADCKPSVVYRTQVQYSTVVVPSTVYKTNVQYITQTSVRTQQVLTTLYSQIVRTQQVPSVRYQTITVTRTQENLRTQVVTLPPQVNYVTRTQQSVRTQVQYQTRYETRIQQVPTTIVRNVVSTMVPKQVVSTVYRTQTVIRTQQLPDQTRIVPTTQYSTRYSTVVIPAQNVVRTTQLVRTNVVTQTITQPGQTRVITSTQLVPVTTTVISQVVRTNTQIQYVTRTQVEQRVSTVVRTQQVPQYNTRIVTVPQQVVRTQVSTRVVPTTIYAQRTASSYINLPAQTRYVTVTQTSVRTQQLAGQTRTQYNTRIVYNTNYVTSTVYREQYNTVTATQTVKGDCGYSYAAPARAFNPFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M2F6</accession>
    <name>A0A3R7M2F6_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BtpA domain containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_016577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BtpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01003084">
        <property type="protein sequence ID" value="ROT65436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M2F6"/>
    <dbReference type="STRING" id="6689.A0A3R7M2F6"/>
    <dbReference type="OrthoDB" id="10045006at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005137">
        <property type="entry name" value="BtpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00259">
        <property type="entry name" value="thylakoid_BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21381:SF3">
        <property type="entry name" value="SGC REGION PROTEIN SGCQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21381">
        <property type="entry name" value="ZGC:162297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03437">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005956">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT65436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="27444" checksum="575C783913F5B9C8" modified="2019-04-10" version="1">MALSRFKDLFQCSRAAVIGMIHVKALPGTPLNRHGINELVEMARQEAFAYKEAGVDGVLVENMFDIPYLMGASLGPEVVATMTRVCQEVRSIIPKRIPCGIQILAGGNKEALAVGKACGLQFIRAECFVFSHVADEGLMNACAGPLLRYRRSIGAEDVLVFTDIKKKHSWDCAHSITSDVGIADTAEAAKFFLADGVILTGSATGQEADHRQLENVISKVDLPVLIGSGVTSDNVHKYMDAHGFIVGSHFKTGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M3X6</accession>
    <name>A0A3R7M3X6_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_015439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002920">
        <property type="protein sequence ID" value="ROT66535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M3X6"/>
    <dbReference type="STRING" id="6689.A0A3R7M3X6"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="604"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="651"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT66535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="780" mass="89547" checksum="C90F194E56893103" modified="2019-04-10" version="1">MYKIRGKRQIKTTLIRTRRKGKHKTEKDKEGGRVNHEGARDGEGQRRARPAPKLWRERCRPRGGPTGFREGRGLTRCLCRTRREPNQEVAETEGPDRRGRTEGPRQKGQTEGGRDRRARQKGRDRRGRDRNETEGPRQKGPRPEGAETEGARDRKAETESRAEDRRGETEEGAETEGPNETEGPERAETEGAETEGAETEQTEGAETEWADRRGRDREGRTEGAETEGQRQKGRDRAEGQNRRAEGAETEGPRQKGGRRQKGPRQKGPRQKGRDKKGPRQKGPRRTRQKGRDRRAETEGAETERGETEGAETEAETAETEGAETEGAETEGAETEGAETEGAETEGRDRKGRENRRSRDRRPSRRSRDRRAETEDRRGRDRRGRDRRAETEGAETERPRQKGRDRRGRDRAETEGERGPDRKGPRQKGPRQKGETEGRDRRGRDRRGRDRTRQKGPRQKEPRQKGPRQKGQRQKEKKGETEGRDRRARRAETEQRQKGPRQKGRTESGRDRRADKAETEGAETEGPRQKGQRQRGETEGAETEGAETEGAEQKETEGAETERRDRRGRDRREGRQKAEQRGPRQKGPRQKGPRQKGPRQEGRDRKRQKGQRQKGPRQKEPRQKGPRQKGPRQKGPRQKGQRQKGPRRSRDRRGDRRAETEGAETEGRDRRGREGAETEGAETEDRRGRERAEKGQRPETEGRGAETEGRDRRARQKGRDRRENRRGRDRTEGAETEGAETADSKSRKRRRRRGRGRRANGNGRKIGSVKRVENSSLLRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M4B2</accession>
    <name>A0A3R7M4B2_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">C7M84_009064</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="3">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002138">
        <property type="protein sequence ID" value="ROT72532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M4B2"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROT72532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="506" mass="56207" checksum="9948CFB147018A1E" modified="2019-04-10" version="1">METVKKTPPTGKNFSPSRTRIFAGPDPNRKTPSPVRAILHGEADQSFPTTSSDCTLTSAHQGTAISAVISMTSTAAGDSNALKVCSSDIASITQSLLYGENAAEIKVALNDFTSRSDDMNKDSLGSRSTSTETTFDCENGTCEGKEMKCRRCGKTVPKVLKTAGNAVGEPLTQGTLNEYQSLNKQCNKSRKSKENERDISSSNPAAHQPKKYTRPRCYSALLSTCTRNVKKKGSRRSSVDVLYAREPTEPNIEKIKSKRRLSRQTDVSSFELMTLAEGNENDDNLLQDSSKVAQKPREPKIIKRTFENRNPPKATLIPKSPNFGKCPQFTASISTDSCPPAPWNSLETNYSSSQDIEDRYTNYPEHFSDDHRRDSSRSVNTTSLQQNVLEEEEPEVLEEKLNDLENECGDDGEVVLEPSDDEPLNLDNLEDVIRNMTSRGAKKKKKKKSTDSLGSKRSRKKSDQEFLEGTWAPESIIIIALLVYLACKAIRFLVLLLPSCRKRRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M515</accession>
    <name>A0A3R7M515_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acrosomal protein SP-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_008505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002070">
        <property type="protein sequence ID" value="ROT73082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M515"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT73082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="808" mass="81462" checksum="3D8A36188D408C3A" modified="2019-04-10" version="1">MQWGLSNGCDSEWSSGPESRSSRCGADSHRFICAADLQVCSGRAFKGTSFGRGAAAPSGDEALAAAPVWTRRQRRPSGDCSGARCTRPFSGDEALATAPVGDEALAAAPFGDESLAAAPFGEGPRSGRPSGTSPRSGALRGTRPSQRRPSGDEALSDEPLQRRPSGGRGPCSGVRGGRGPCSGARRGEALAAAPVGGRGPPAAPFGSAPVGTRPSAAPFGDESLSGTSAPFARPSAAPGDEALAAAPVGGRGPRSGALRGTRPSQRRPRGRGPRSGARRGTRQASFGGRGPARLGRGPCSGGLRGRGPCSGARRGTRPLQAAPVGDAQRRPSGTRPSQRPFGDEALAAAPTRPLQRRPSGDEALAAAPFGGRGPCSGVLRGTRPLQRRPSGDEALAAAPVGGRGPRSGARRGRGPRSGALRGTRPLQRRPSGDEALAAAAFGGRGPCSGAHRGTKQRRPSGTRPSQRRPSGDEALAAAPFGGRRPFAARGDEASGALRGRGPCSGAFGDRALAAGEAPCSGALGDEASQRPSLRGRRPSQRAPVGGRGPRSGVLRGRPSAGALRGTRPLQRRPSGDEALAAAAFGATSRLQNERPHRTSPRTAPSGPPQRQALRHEPCSAPSGDAGPCSGAPLQGDAGSSGPAARPPSRGNEALAARDEALFGRTAALASGVLRASPRSRRPSGDEPSSGALRGEALAAAPSGAHEPLVALRGRALAAPPVDEPPARPSGTSPPRAPSGDEALQRALRDEPLPAGRGPFCSMESPFLAGRGPRSGGLRARALAAAPFGDEPCSAALGTRPCSGARRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M8S8</accession>
    <name>A0A3R7M8S8_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative proclotting enzyme isoform X4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">C7M84_011561</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="11">Muscle</tissue>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S1 family. CLIP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01002458">
        <property type="protein sequence ID" value="ROT70169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M8S8"/>
    <dbReference type="OrthoDB" id="6348928at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00190">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000006">
        <property type="entry name" value="Serine proteinase stubble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022700">
        <property type="entry name" value="CLIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001314">
        <property type="entry name" value="Peptidase_S1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252">
        <property type="entry name" value="ACROSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24252:SF7">
        <property type="entry name" value="HYALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00722">
        <property type="entry name" value="CHYMOTRYPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00680">
        <property type="entry name" value="CLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00020">
        <property type="entry name" value="Tryp_SPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51888">
        <property type="entry name" value="CLIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50240">
        <property type="entry name" value="TRYPSIN_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Clip" evidence="10">
        <location>
            <begin position="363"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="9">
        <location>
            <begin position="481"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="414"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="414"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="429"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROT70169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="729" mass="79484" checksum="7BDA61931B7241A4" modified="2019-04-10" version="1">MSEDLNTPGECDSQPGQFPPQHTSAYCKVSRFPGNNSSPCESHSAPPPRFARRRAFRRSRRAGLAAAVNSMLRHMGHSFQNGWYTLGKTLDRHVVPHVRYAAERITEDVAPSIGHALMRAGNQVALRTAEGLQAGAQVIKTKIVPAIEERLVQASNAAVPVINHGLDVLEATIQKSADAVSKSTAKGIDRLSSKVLGEQRHTRVKTIANNIHGGINNGLNSLAGAINNLNSRNTNSDAFTDQDYHDYVLSQYTSDSSRGPQYVPEYPDAHYPPDYPTDYSQYSYQLQTPPQTVGGALSQVVTNGAYTLSRHVLGHNLTDALAPIAKSVSNVVGQTIPAVSLGDGRIVIDLPNTDVERDDSARSCTTPVGEAGLCKDLSDCPDLILDLTNLRKSVCFKSLFVPGVCCPIKDLDPNSVHSPSSVTSRPRPTSRPRPVTLPPQPPRPLPPVPGTSPRPVPIQPVAEVARPNFECGQPKIPTFRVVGGDESRRGQWPWIAAVWLHGPKKTVFWCGGSLISKQYVLTAAHCTKDTRGKTFDAQQFSVRLGDHNIFSESDDFISNPQTYRVLSIRPHPEFISHGFYNDVALLKLDRPVDFTEYILPVCLPPADMARQPLDHMVGQTPSVIGWGSTVYGGHESAVLREVQVPVWKNSDCDEAYTQPITSAFICAGFTEGGRDACQGDSGGPLQLYINGNWIQIGIVSFAIRCAEPGHPGVYTRLTEFLPWIHSNMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7M9D3</accession>
    <name>A0A3R7M9D3_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">C7M84_005805</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="10">Muscle</tissue>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001749">
        <property type="protein sequence ID" value="ROT75627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7M9D3"/>
    <dbReference type="STRING" id="6689.A0A3R7M9D3"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000113">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF16">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="241"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="35"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="98"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="337"/>
            <end position="344"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROT75627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="605" mass="67335" checksum="8180F9759ED5C7D1" modified="2019-04-10" version="1">MHYSARETTRRAHALTISPSSPALDVASKIHDPAATFQVNKDPPVSLKENGSLKENGNLKENGNAKSKTSTDDPDVVKVLRKATYKVSGDTQKLRQLCTEFDAKEEDYKKRIHDLETELRNHQNESTKTHDRDIREMENRMELVAQKLEAAERYMAGKEEECNMLKLDLDTLNEENKRLKENLNDMMLKLQDYEEILAQKKTLNEQYSRILEEHRVLSEDFNRERVLRKKYYNQVEEMKGKIRVFCRVRPITESERRRGSSGSSGSSGGGGAGDASIVVSAEDEYSVSLNTQRGGQRSFLFDRVFQEHEDQEAVFRDTHALVQSALDGYNVTIMAYGQTGSGKTYTMLGTPEEPGIAPRAFTRLFQLLDEGRARQEAAVSTYMLELYNDKLIDLLKPAVGADTDRLDIKRDKKGAVHVQGAAVRSVSSASELNRAFNEGLANRHTAATKMNVESSRSHLLIAVCLSITSKQTGSVLRGKLTLVDLAGSERVSKSGASSDQLKEANSINKSLSALGDVISALSSESSFVPYRNSKLTMLLQDSLGGTAKTLVFVNASPAAYNADETLISLMYATRIKQITNNVCKNADNKEITRLKSVISKKKGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MD23</accession>
    <name>A0A3R7MD23_PENVA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">C7M84_001876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="2">Muscle</tissue>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="QCYY01001251">
        <property type="protein sequence ID" value="ROT79393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A3R7MD23"/>
    <dbReference type="OrthoDB" id="6349642at2759"/>
    <dbReference type="Proteomes" id="UP000283509">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018576769" evidence="1">
        <location>
            <begin position="17"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ROT79393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000283509"/>
        </source>
    </evidence>
    <sequence length="178" mass="18619" checksum="C4C7AA9D6C37402A" modified="2019-04-10" version="1">MKFMVILAVAGIAAAAAPFRTSYSAPGGGKYIVTQDNSFEYGVRDTSLEYVRNVGELANVGAAGGPVSVKSATDNQLQTFPYAIGLDSSEEVMVHAGKLGDLGARTRSARVKTLSHMLNSGYVDASDEFRFRSNLARATALGGKNYYINDSGELFYREGAGAHRGGPSAAAGQGVQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-04-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A3R7MHS2</accession>
    <name>A0A3R7MHS2_PENVA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">C7M84_023930</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Penaeus vannamei</name>
        <name type="common">Whiteleg shrimp</name>
        <name type="synonym">Litopenaeus vannamei</name>
        <dbReference type="NCBI Taxonomy" id="6689"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Metazoa</taxon>
            <taxon>Ecdysozoa</taxon>
            <taxon>Arthropoda</taxon>
            <taxon>Crustacea</taxon>
            <taxon>Multicrustacea</taxon>
            <taxon>Malacostraca</taxon>
            <taxon>Eumalacostraca</taxon>
            <taxon>Eucarida</taxon>
            <taxon>Decapoda</taxon>
            <taxon>Dendrobranchiata</taxon>
            <taxon>Penaeoidea</taxon>
            <taxon>Penaeidae</taxon>
            <taxon>Penaeus</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2018-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Zhang X."/>
                <person name="Yuan J."/>
                <person name="Li F."/>
                <person name="Xiang J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2019-01" db="EMBL/GenBank/DDBJ databases">
            <title>The decoding of complex shrimp genome reveals the adaptation for benthos swimmer, frequently molting mechanism and breeding impact on genome.</title>
            <authorList>
                <person name="Sun Y."/>
                <person name="Gao Y."/>
                <person name="Yu Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <tissue evidence="16">Muscle</tissue>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReferenc
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